LOCUS       DARPZF010000001       182818 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.001, whole genome shotgun sequence.
ACCESSION   DARPZF010000001 DARPZF010000000
VERSION     DARPZF010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 182818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 182818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..182818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.001"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..2327)
                     /gene="esp"
                     /locus_tag="SLE65_000001"
     CDS             complement(<1..2327)
                     /gene="esp"
                     /locus_tag="SLE65_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HEI8447333.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
     gene            complement(2944..3378)
                     /locus_tag="SLE65_000002"
     CDS             complement(2944..3378)
                     /locus_tag="SLE65_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447334.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3395..4600)
                     /locus_tag="SLE65_000003"
     CDS             complement(3395..4600)
                     /locus_tag="SLE65_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEI8447335.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            5294..5680
                     /locus_tag="SLE65_000004"
     CDS             5294..5680
                     /locus_tag="SLE65_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEI8447336.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            5774..5965
                     /locus_tag="SLE65_000005"
     CDS             5774..5965
                     /locus_tag="SLE65_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8447337.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            6479..6811
                     /locus_tag="SLE65_000006"
     CDS             6479..6811
                     /locus_tag="SLE65_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8447338.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            6721..6915
                     /locus_tag="SLE65_000007"
     CDS             6721..6915
                     /locus_tag="SLE65_000007"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEI8447339.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKC"
     gene            7107..7262
                     /locus_tag="SLE65_000008"
     CDS             7107..7262
                     /locus_tag="SLE65_000008"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HEI8447340.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            7538..8878
                     /locus_tag="SLE65_000009"
                     /pseudo
     CDS             7538..8878
                     /locus_tag="SLE65_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9119..10735)
                     /locus_tag="SLE65_000010"
     CDS             complement(9119..10735)
                     /locus_tag="SLE65_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HEI8447341.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            10853..11071
                     /locus_tag="SLE65_000011"
     CDS             10853..11071
                     /locus_tag="SLE65_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8447342.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            11266..11727
                     /locus_tag="SLE65_000012"
     CDS             11266..11727
                     /locus_tag="SLE65_000012"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEI8447343.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(11920..12159)
                     /locus_tag="SLE65_000013"
     CDS             complement(11920..12159)
                     /locus_tag="SLE65_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8447344.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(12183..13706)
                     /locus_tag="SLE65_000014"
     CDS             complement(12183..13706)
                     /locus_tag="SLE65_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEI8447345.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(13724..13846)
                     /locus_tag="SLE65_000015"
     CDS             complement(13724..13846)
                     /locus_tag="SLE65_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEI8447346.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(13876..14859)
                     /locus_tag="SLE65_000016"
     CDS             complement(13876..14859)
                     /locus_tag="SLE65_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HEI8447347.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(14883..15032)
                     /gene="rpmG"
                     /locus_tag="SLE65_000017"
     CDS             complement(14883..15032)
                     /gene="rpmG"
                     /locus_tag="SLE65_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEI8447348.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(15053..15430)
                     /locus_tag="SLE65_000018"
     CDS             complement(15053..15430)
                     /locus_tag="SLE65_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447349.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(15462..15641)
                     /gene="rpmF"
                     /locus_tag="SLE65_000019"
     CDS             complement(15462..15641)
                     /gene="rpmF"
                     /locus_tag="SLE65_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEI8447350.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(15656..15925)
                     /gene="rpsN"
                     /locus_tag="SLE65_000020"
     CDS             complement(15656..15925)
                     /gene="rpsN"
                     /locus_tag="SLE65_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEI8447351.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(16448..18214)
                     /locus_tag="SLE65_000021"
     CDS             complement(16448..18214)
                     /locus_tag="SLE65_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8447352.1"
                     /translation="MQMIGGLTMKNFYKKKFALTDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENAKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(18174..19928)
                     /locus_tag="SLE65_000022"
     CDS             complement(18174..19928)
                     /locus_tag="SLE65_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8447353.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQYLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHRVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(20038..20607)
                     /locus_tag="SLE65_000023"
     CDS             complement(20038..20607)
                     /locus_tag="SLE65_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEI8447354.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVVSWVLMQLGSAAGQWIPIWFFTDRFRQDWIDRGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(20625..22040)
                     /locus_tag="SLE65_000024"
     CDS             complement(20625..22040)
                     /locus_tag="SLE65_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HEI8447355.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQNPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(22051..22718)
                     /locus_tag="SLE65_000025"
                     /pseudo
     CDS             complement(22051..22718)
                     /locus_tag="SLE65_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
     gene            complement(22849..23433)
                     /locus_tag="SLE65_000026"
     CDS             complement(22849..23433)
                     /locus_tag="SLE65_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEI8447356.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(23764..23997)
                     /locus_tag="SLE65_000027"
     CDS             complement(23764..23997)
                     /locus_tag="SLE65_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HEI8447357.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(24012..24959)
                     /locus_tag="SLE65_000028"
     CDS             complement(24012..24959)
                     /locus_tag="SLE65_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEI8447358.1"
                     /translation="MRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVVT
                     NSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGG
                     NAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKNI
                     EKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYFS
                     KAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDTN
                     IPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(24959..25801)
                     /locus_tag="SLE65_000029"
     CDS             complement(24959..25801)
                     /locus_tag="SLE65_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEI8447359.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            26123..27310
                     /locus_tag="SLE65_000030"
     CDS             26123..27310
                     /locus_tag="SLE65_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEI8447360.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
     gene            complement(27442..29628)
                     /locus_tag="SLE65_000031"
     CDS             complement(27442..29628)
                     /locus_tag="SLE65_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HEI8447361.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNISVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            29846..30529
                     /locus_tag="SLE65_000032"
     CDS             29846..30529
                     /locus_tag="SLE65_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEI8447362.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            complement(30610..31329)
                     /locus_tag="SLE65_000033"
     CDS             complement(30610..31329)
                     /locus_tag="SLE65_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEI8447363.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(31641..31847)
                     /locus_tag="SLE65_000034"
     CDS             complement(31641..31847)
                     /locus_tag="SLE65_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447364.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            32092..32694
                     /locus_tag="SLE65_000035"
     CDS             32092..32694
                     /locus_tag="SLE65_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HEI8447365.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            32835..34115
                     /locus_tag="SLE65_000036"
     CDS             32835..34115
                     /locus_tag="SLE65_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEI8447366.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            34128..34856
                     /locus_tag="SLE65_000037"
     CDS             34128..34856
                     /locus_tag="SLE65_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8447367.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(34925..36448)
                     /locus_tag="SLE65_000038"
     CDS             complement(34925..36448)
                     /locus_tag="SLE65_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEI8447368.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            36700..37881
                     /locus_tag="SLE65_000039"
     CDS             36700..37881
                     /locus_tag="SLE65_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEI8447369.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(37941..39569)
                     /gene="treC"
                     /locus_tag="SLE65_000040"
     CDS             complement(37941..39569)
                     /gene="treC"
                     /locus_tag="SLE65_000040"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEI8447370.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(40020..42731)
                     /locus_tag="SLE65_000041"
     CDS             complement(40020..42731)
                     /locus_tag="SLE65_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8447371.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGTIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(42741..43442)
                     /locus_tag="SLE65_000042"
     CDS             complement(42741..43442)
                     /locus_tag="SLE65_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8447372.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            43628..44227
                     /locus_tag="SLE65_000043"
     CDS             43628..44227
                     /locus_tag="SLE65_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEI8447373.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            44308..45321
                     /locus_tag="SLE65_000044"
     CDS             44308..45321
                     /locus_tag="SLE65_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEI8447374.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            45429..46346
                     /gene="rbsK"
                     /locus_tag="SLE65_000045"
     CDS             45429..46346
                     /gene="rbsK"
                     /locus_tag="SLE65_000045"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HEI8447375.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            46374..46769
                     /gene="rbsD"
                     /locus_tag="SLE65_000046"
     CDS             46374..46769
                     /gene="rbsD"
                     /locus_tag="SLE65_000046"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HEI8447376.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            46769..48142
                     /locus_tag="SLE65_000047"
     CDS             46769..48142
                     /locus_tag="SLE65_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEI8447377.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            48499..50643
                     /locus_tag="SLE65_000048"
     CDS             48499..50643
                     /locus_tag="SLE65_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HEI8447378.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(50695..51735)
                     /locus_tag="SLE65_000049"
     CDS             complement(50695..51735)
                     /locus_tag="SLE65_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEI8447379.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(52012..53814)
                     /locus_tag="SLE65_000050"
     CDS             complement(52012..53814)
                     /locus_tag="SLE65_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8447380.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(53828..54580)
                     /locus_tag="SLE65_000051"
     CDS             complement(53828..54580)
                     /locus_tag="SLE65_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8447381.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(54589..54951)
                     /locus_tag="SLE65_000052"
     CDS             complement(54589..54951)
                     /locus_tag="SLE65_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEI8447382.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(55127..55999)
                     /locus_tag="SLE65_000053"
     CDS             complement(55127..55999)
                     /locus_tag="SLE65_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEI8447383.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(56050..56538)
                     /locus_tag="SLE65_000054"
     CDS             complement(56050..56538)
                     /locus_tag="SLE65_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HEI8447384.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(56676..57467)
                     /locus_tag="SLE65_000055"
     CDS             complement(56676..57467)
                     /locus_tag="SLE65_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEI8447385.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(57522..58130)
                     /locus_tag="SLE65_000056"
     CDS             complement(57522..58130)
                     /locus_tag="SLE65_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEI8447386.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLVWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(58123..58440)
                     /locus_tag="SLE65_000057"
     CDS             complement(58123..58440)
                     /locus_tag="SLE65_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEI8447387.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(58596..59324)
                     /locus_tag="SLE65_000058"
     CDS             complement(58596..59324)
                     /locus_tag="SLE65_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HEI8447388.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            59483..60364
                     /locus_tag="SLE65_000059"
     CDS             59483..60364
                     /locus_tag="SLE65_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEI8447389.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(60601..61644)
                     /locus_tag="SLE65_000060"
     CDS             complement(60601..61644)
                     /locus_tag="SLE65_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEI8447390.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(61647..62315)
                     /locus_tag="SLE65_000061"
     CDS             complement(61647..62315)
                     /locus_tag="SLE65_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8447391.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            62457..64793
                     /locus_tag="SLE65_000062"
     CDS             62457..64793
                     /locus_tag="SLE65_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8447392.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(64908..65219)
                     /locus_tag="SLE65_000063"
     CDS             complement(64908..65219)
                     /locus_tag="SLE65_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447393.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            65400..66875
                     /locus_tag="SLE65_000064"
     CDS             65400..66875
                     /locus_tag="SLE65_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HEI8447394.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPTMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            66922..67506
                     /locus_tag="SLE65_000065"
     CDS             66922..67506
                     /locus_tag="SLE65_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HEI8447395.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            67508..67927
                     /locus_tag="SLE65_000066"
     CDS             67508..67927
                     /locus_tag="SLE65_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HEI8447396.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(68208..68492)
                     /locus_tag="SLE65_000067"
     CDS             complement(68208..68492)
                     /locus_tag="SLE65_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HEI8447397.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(68844..69554)
                     /locus_tag="SLE65_000068"
     CDS             complement(68844..69554)
                     /locus_tag="SLE65_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HEI8447398.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(69551..71023)
                     /locus_tag="SLE65_000069"
     CDS             complement(69551..71023)
                     /locus_tag="SLE65_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEI8447399.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            71161..71634
                     /locus_tag="SLE65_000070"
     CDS             71161..71634
                     /locus_tag="SLE65_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEI8447400.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(71787..72338)
                     /locus_tag="SLE65_000071"
     CDS             complement(71787..72338)
                     /locus_tag="SLE65_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEI8447401.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            72443..72973
                     /locus_tag="SLE65_000072"
     CDS             72443..72973
                     /locus_tag="SLE65_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HEI8447402.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(73456..73899)
                     /locus_tag="SLE65_000073"
     CDS             complement(73456..73899)
                     /locus_tag="SLE65_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8447403.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(73915..75075)
                     /locus_tag="SLE65_000074"
     CDS             complement(73915..75075)
                     /locus_tag="SLE65_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEI8447404.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            75582..77282
                     /locus_tag="SLE65_000075"
     CDS             75582..77282
                     /locus_tag="SLE65_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447405.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(77384..78217)
                     /locus_tag="SLE65_000076"
     CDS             complement(77384..78217)
                     /locus_tag="SLE65_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEI8447406.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(78521..80686)
                     /locus_tag="SLE65_000077"
     CDS             complement(78521..80686)
                     /locus_tag="SLE65_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEI8447407.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            80946..83240
                     /locus_tag="SLE65_000078"
     CDS             80946..83240
                     /locus_tag="SLE65_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HEI8447408.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFKLLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            83233..83898
                     /gene="pgmB"
                     /locus_tag="SLE65_000079"
     CDS             83233..83898
                     /gene="pgmB"
                     /locus_tag="SLE65_000079"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HEI8447409.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFTKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            83891..84898
                     /locus_tag="SLE65_000080"
     CDS             83891..84898
                     /locus_tag="SLE65_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEI8447410.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            84920..85939
                     /locus_tag="SLE65_000081"
     CDS             84920..85939
                     /locus_tag="SLE65_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8447411.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(86220..87588)
                     /gene="nhaC"
                     /locus_tag="SLE65_000082"
                     /pseudo
     CDS             complement(86220..87588)
                     /gene="nhaC"
                     /locus_tag="SLE65_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
     gene            complement(87697..89118)
                     /locus_tag="SLE65_000083"
     CDS             complement(87697..89118)
                     /locus_tag="SLE65_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8447412.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(89361..91238)
                     /gene="tdc"
                     /locus_tag="SLE65_000084"
     CDS             complement(89361..91238)
                     /gene="tdc"
                     /locus_tag="SLE65_000084"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HEI8447413.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(91529..92785)
                     /locus_tag="SLE65_000085"
     CDS             complement(91529..92785)
                     /locus_tag="SLE65_000085"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEI8447414.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(92897..93102)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            93365..94666
                     /locus_tag="SLE65_000086"
     CDS             93365..94666
                     /locus_tag="SLE65_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEI8447415.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(94735..95334)
                     /locus_tag="SLE65_000087"
     CDS             complement(94735..95334)
                     /locus_tag="SLE65_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEI8447416.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            95588..96469
                     /locus_tag="SLE65_000088"
     CDS             95588..96469
                     /locus_tag="SLE65_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8447417.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            96482..98092
                     /locus_tag="SLE65_000089"
     CDS             96482..98092
                     /locus_tag="SLE65_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HEI8447418.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(98169..98828)
                     /locus_tag="SLE65_000090"
     CDS             complement(98169..98828)
                     /locus_tag="SLE65_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEI8447419.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(99111..99776)
                     /locus_tag="SLE65_000091"
     CDS             complement(99111..99776)
                     /locus_tag="SLE65_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HEI8447420.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(99923..100528)
                     /gene="dhaL"
                     /locus_tag="SLE65_000092"
     CDS             complement(99923..100528)
                     /gene="dhaL"
                     /locus_tag="SLE65_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HEI8447421.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(100556..101566)
                     /gene="dhaK"
                     /locus_tag="SLE65_000093"
     CDS             complement(100556..101566)
                     /gene="dhaK"
                     /locus_tag="SLE65_000093"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HEI8447422.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(101541..101987)
                     /gene="dhaM"
                     /locus_tag="SLE65_000094"
     CDS             complement(101541..101987)
                     /gene="dhaM"
                     /locus_tag="SLE65_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEI8447423.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            102090..102410
                     /locus_tag="SLE65_000095"
     CDS             102090..102410
                     /locus_tag="SLE65_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HEI8447424.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(102522..103391)
                     /locus_tag="SLE65_000096"
     CDS             complement(102522..103391)
                     /locus_tag="SLE65_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEI8447425.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(103487..104791)
                     /locus_tag="SLE65_000097"
     CDS             complement(103487..104791)
                     /locus_tag="SLE65_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEI8447426.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(104788..105297)
                     /locus_tag="SLE65_000098"
     CDS             complement(104788..105297)
                     /locus_tag="SLE65_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447427.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(105472..107607)
                     /locus_tag="SLE65_000099"
     CDS             complement(105472..107607)
                     /locus_tag="SLE65_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEI8447428.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(107690..109345)
                     /locus_tag="SLE65_000100"
     CDS             complement(107690..109345)
                     /locus_tag="SLE65_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEI8447429.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(109347..109661)
                     /locus_tag="SLE65_000101"
     CDS             complement(109347..109661)
                     /locus_tag="SLE65_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEI8447430.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            109831..110091
                     /locus_tag="SLE65_000102"
     CDS             109831..110091
                     /locus_tag="SLE65_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEI8447431.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            110105..110419
                     /locus_tag="SLE65_000103"
     CDS             110105..110419
                     /locus_tag="SLE65_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HEI8447432.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(111149..111703)
                     /locus_tag="SLE65_000104"
     CDS             complement(111149..111703)
                     /locus_tag="SLE65_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HEI8447433.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(111829..113758)
                     /locus_tag="SLE65_000105"
                     /pseudo
     CDS             complement(111829..113758)
                     /locus_tag="SLE65_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(114064..114780)
                     /locus_tag="SLE65_000106"
     CDS             complement(114064..114780)
                     /locus_tag="SLE65_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEI8447434.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(114781..116604)
                     /gene="glpO"
                     /locus_tag="SLE65_000107"
     CDS             complement(114781..116604)
                     /gene="glpO"
                     /locus_tag="SLE65_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEI8447435.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(116618..118114)
                     /gene="glpK"
                     /locus_tag="SLE65_000108"
     CDS             complement(116618..118114)
                     /gene="glpK"
                     /locus_tag="SLE65_000108"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEI8447436.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(118250..119710)
                     /locus_tag="SLE65_000109"
     CDS             complement(118250..119710)
                     /locus_tag="SLE65_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8447437.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(119700..120995)
                     /locus_tag="SLE65_000110"
     CDS             complement(119700..120995)
                     /locus_tag="SLE65_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEI8447438.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(121327..122004)
                     /locus_tag="SLE65_000111"
     CDS             complement(121327..122004)
                     /locus_tag="SLE65_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HEI8447439.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(122034..123125)
                     /locus_tag="SLE65_000112"
     CDS             complement(122034..123125)
                     /locus_tag="SLE65_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HEI8447440.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(123226..123660)
                     /locus_tag="SLE65_000113"
     CDS             complement(123226..123660)
                     /locus_tag="SLE65_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEI8447441.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(124244..125701)
                     /gene="ascB"
                     /locus_tag="SLE65_000114"
     CDS             complement(124244..125701)
                     /gene="ascB"
                     /locus_tag="SLE65_000114"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEI8447442.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(125698..127593)
                     /locus_tag="SLE65_000115"
     CDS             complement(125698..127593)
                     /locus_tag="SLE65_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEI8447443.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(127651..129426)
                     /locus_tag="SLE65_000116"
     CDS             complement(127651..129426)
                     /locus_tag="SLE65_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HEI8447444.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(129476..130972)
                     /locus_tag="SLE65_000117"
     CDS             complement(129476..130972)
                     /locus_tag="SLE65_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEI8447445.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(131166..132788)
                     /locus_tag="SLE65_000118"
     CDS             complement(131166..132788)
                     /locus_tag="SLE65_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEI8447446.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(133116..134429)
                     /locus_tag="SLE65_000119"
     CDS             complement(133116..134429)
                     /locus_tag="SLE65_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEI8447447.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(134674..134898)
                     /locus_tag="SLE65_000120"
     CDS             complement(134674..134898)
                     /locus_tag="SLE65_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447448.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(134918..135340)
                     /locus_tag="SLE65_000121"
     CDS             complement(134918..135340)
                     /locus_tag="SLE65_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEI8447449.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(135483..136193)
                     /locus_tag="SLE65_000122"
     CDS             complement(135483..136193)
                     /locus_tag="SLE65_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447450.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(136211..136708)
                     /locus_tag="SLE65_000123"
     CDS             complement(136211..136708)
                     /locus_tag="SLE65_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8447451.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(136745..137197)
                     /locus_tag="SLE65_000124"
     CDS             complement(136745..137197)
                     /locus_tag="SLE65_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEI8447452.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(137332..137937)
                     /locus_tag="SLE65_000125"
     CDS             complement(137332..137937)
                     /locus_tag="SLE65_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEI8447453.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(138387..139007)
                     /locus_tag="SLE65_000126"
     CDS             complement(138387..139007)
                     /locus_tag="SLE65_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEI8447454.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(139009..139878)
                     /locus_tag="SLE65_000127"
     CDS             complement(139009..139878)
                     /locus_tag="SLE65_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HEI8447455.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(139901..140308)
                     /locus_tag="SLE65_000128"
     CDS             complement(139901..140308)
                     /locus_tag="SLE65_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEI8447456.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(140327..141616)
                     /locus_tag="SLE65_000129"
     CDS             complement(140327..141616)
                     /locus_tag="SLE65_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8447457.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGDFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(141643..141945)
                     /locus_tag="SLE65_000130"
     CDS             complement(141643..141945)
                     /locus_tag="SLE65_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8447458.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(141970..144063)
                     /locus_tag="SLE65_000131"
     CDS             complement(141970..144063)
                     /locus_tag="SLE65_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEI8447459.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(144552..145316)
                     /locus_tag="SLE65_000132"
     CDS             complement(144552..145316)
                     /locus_tag="SLE65_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HEI8447460.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(145427..146296)
                     /gene="mdcB"
                     /locus_tag="SLE65_000133"
     CDS             complement(145427..146296)
                     /gene="mdcB"
                     /locus_tag="SLE65_000133"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HEI8447461.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(146321..147397)
                     /locus_tag="SLE65_000134"
     CDS             complement(146321..147397)
                     /locus_tag="SLE65_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HEI8447462.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(147421..148014)
                     /locus_tag="SLE65_000135"
     CDS             complement(147421..148014)
                     /locus_tag="SLE65_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HEI8447463.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(148018..149694)
                     /gene="mdcD"
                     /locus_tag="SLE65_000136"
     CDS             complement(148018..149694)
                     /gene="mdcD"
                     /locus_tag="SLE65_000136"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HEI8447464.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(149684..149983)
                     /locus_tag="SLE65_000137"
     CDS             complement(149684..149983)
                     /locus_tag="SLE65_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HEI8447465.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(150085..151731)
                     /gene="mdcA"
                     /locus_tag="SLE65_000138"
     CDS             complement(150085..151731)
                     /gene="mdcA"
                     /locus_tag="SLE65_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HEI8447466.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(151738..152649)
                     /locus_tag="SLE65_000139"
     CDS             complement(151738..152649)
                     /locus_tag="SLE65_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEI8447467.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            152769..153626
                     /locus_tag="SLE65_000140"
     CDS             152769..153626
                     /locus_tag="SLE65_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEI8447468.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(153813..154175)
                     /locus_tag="SLE65_000141"
     CDS             complement(153813..154175)
                     /locus_tag="SLE65_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEI8447469.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            154521..155960
                     /locus_tag="SLE65_000142"
     CDS             154521..155960
                     /locus_tag="SLE65_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8447470.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(155967..158519)
                     /locus_tag="SLE65_000143"
     CDS             complement(155967..158519)
                     /locus_tag="SLE65_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEI8447471.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(158633..159964)
                     /locus_tag="SLE65_000144"
     CDS             complement(158633..159964)
                     /locus_tag="SLE65_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8447472.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(159930..161408)
                     /locus_tag="SLE65_000145"
     CDS             complement(159930..161408)
                     /locus_tag="SLE65_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8447473.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(161713..163548)
                     /gene="tdc"
                     /locus_tag="SLE65_000146"
     CDS             complement(161713..163548)
                     /gene="tdc"
                     /locus_tag="SLE65_000146"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HEI8447474.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            164018..165445
                     /locus_tag="SLE65_000147"
     CDS             164018..165445
                     /locus_tag="SLE65_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8447475.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(165537..165902)
                     /locus_tag="SLE65_000148"
     CDS             complement(165537..165902)
                     /locus_tag="SLE65_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HEI8447476.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(165899..166264)
                     /locus_tag="SLE65_000149"
     CDS             complement(165899..166264)
                     /locus_tag="SLE65_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HEI8447477.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(166456..166704)
                     /locus_tag="SLE65_000150"
     CDS             complement(166456..166704)
                     /locus_tag="SLE65_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447478.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            166703..166831
                     /locus_tag="SLE65_000151"
     CDS             166703..166831
                     /locus_tag="SLE65_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HEI8447479.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            166888..168582
                     /locus_tag="SLE65_000152"
     CDS             166888..168582
                     /locus_tag="SLE65_000152"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HEI8447480.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            168586..168705
                     /locus_tag="SLE65_000153"
                     /pseudo
     CDS             168586..168705
                     /locus_tag="SLE65_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            169356..170489
                     /locus_tag="SLE65_000154"
     CDS             169356..170489
                     /locus_tag="SLE65_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEI8447481.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            170520..170840
                     /locus_tag="SLE65_000155"
     CDS             170520..170840
                     /locus_tag="SLE65_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HEI8447482.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(170869..171333)
                     /locus_tag="SLE65_000156"
     CDS             complement(170869..171333)
                     /locus_tag="SLE65_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8447483.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(171465..172719)
                     /locus_tag="SLE65_000157"
                     /pseudo
     CDS             complement(171465..172719)
                     /locus_tag="SLE65_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(172748..173065)
                     /locus_tag="SLE65_000158"
     CDS             complement(172748..173065)
                     /locus_tag="SLE65_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEI8447484.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(173091..173411)
                     /locus_tag="SLE65_000159"
     CDS             complement(173091..173411)
                     /locus_tag="SLE65_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8447485.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(173875..175290)
                     /locus_tag="SLE65_000160"
     CDS             complement(173875..175290)
                     /locus_tag="SLE65_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEI8447486.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(175307..176623)
                     /locus_tag="SLE65_000161"
     CDS             complement(175307..176623)
                     /locus_tag="SLE65_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8447487.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(176773..177471)
                     /locus_tag="SLE65_000162"
     CDS             complement(176773..177471)
                     /locus_tag="SLE65_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEI8447488.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(177760..178716)
                     /locus_tag="SLE65_000163"
     CDS             complement(177760..178716)
                     /locus_tag="SLE65_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEI8447489.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(178829..179662)
                     /gene="msrA"
                     /locus_tag="SLE65_000164"
     CDS             complement(178829..179662)
                     /gene="msrA"
                     /locus_tag="SLE65_000164"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEI8447490.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(179837..181465)
                     /locus_tag="SLE65_000165"
     CDS             complement(179837..181465)
                     /locus_tag="SLE65_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447491.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIRLVSKGFKNADFIAI
                     FKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNNDL
                     TTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAKLL
                     QFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFNQK
                     IISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNLPY
                     KTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGVAD
                     IKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(181452..182786)
                     /locus_tag="SLE65_000166"
     CDS             complement(181452..182786)
                     /locus_tag="SLE65_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447492.1"
                     /translation="MDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
BASE COUNT        54731 a        37237 c        30992 g        59858 t
ORIGIN      
        1 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
       61 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      121 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      181 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtcctt attatagaca
      241 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      301 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      361 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      421 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      481 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      541 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      601 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      661 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      721 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      781 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      841 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      901 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
      961 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1021 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1081 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1141 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1201 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1261 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1321 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1381 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1441 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1501 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1561 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1621 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1681 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1741 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1801 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1861 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1921 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     1981 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2041 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2101 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2161 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2221 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2281 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2341 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2401 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2461 caacaaaaaa agtacatttc ttcatgtttt tttcggatat ttgtgctttt taaccattca
     2521 gcagctgaaa acatataaaa agatatgtat gtattctttc tgaaattaag ttcatttcta
     2581 tgcgatgaag catgttttca aaatattacc ctttcttaga ttaaacttca gagtattcaa
     2641 ataacggaat aaggagcctt atcccgcatt actgaatgag actgtgacat aagtaaaaag
     2701 gtgacttcaa attccttctt cggaatttga aatcaccttc tttataatta taaagtatcg
     2761 gtttcacagc atttctgaat gattcctaga atcttaaacg aatgattgga gttatcaaca
     2821 ttttttcact cgtttttagc gaaacaaaaa atgacatttg tcacagcctc attaaattat
     2881 tgattctttt tctttataat tgaattgtcc atatttaaag tgtctagtac tctacatgaa
     2941 taattaattg ctttcactca aatacttata atctattaac ttgtagttgt ttaacttttc
     3001 tgaaaaagtt agacccacgt aataatcttc ccagctttct ctttcaatta actgatccaa
     3061 tttttgataa tccataaatt catcatgtat caaaaagaat aaataacttg atattttagc
     3121 atctagctta atcagattaa ataatgtttg tttaaaattg ctaccattaa tatgactgat
     3181 agattctcta gcttcttcac ataaactttt tactttatta attactactt tgtcatattc
     3241 atttaacaca ctattattac cattacttag acgctcagat tctacgaaac aactcaaatc
     3301 agaaatttcc caaaaaaatt ttttgttaaa atccaatttc ctcaactcct ccaaactacg
     3361 taaatgatat agtctcataa taaaataaaa cctctcagct aatgttgttg aaattgtcca
     3421 ctaaacctaa ttgatattgc ttaggagata cacctgcgta ctttttgaat actctcgaaa
     3481 agtgtgaaga atctgaaaat cctaaaccta aagaaacttc actgatagta tggtttgatt
     3541 tcaacattat tttagccgta gaaatttttc gcttagagat ataattataa atcgtaatat
     3601 gcatttcatt cttaaagctt tctcttaatt tagtttcact tacagaaaaa taattagcta
     3661 tttcctttac agtaattctt ttatagatat ttaagccgat gaattgaacg acagaagaaa
     3721 ttaagggaga aagatgctct atcttagttt ttccgatttc cttagtataa taaacaatcc
     3781 cagaatccct cacttttaag acctcaggta acgatacagc taattcgttt tcttgtatca
     3841 aagcatctct actttgatac gcttctatta tatccattcc taatgttata gacgtttgtg
     3901 ctaacttttc aaaaacaatg atagaataat ttttttcaga ccgaatcgta tctccactaa
     3961 cacttggaat tattccatta ctcagattaa aaaccatgtt ttctaaattt cgaatatctc
     4021 catttttaac atattccagt attttatttt cataaagaaa cagatatatt tctggatcgt
     4081 aattttgtga taacagatta tctattttga tttgctcgat agttttactt agattttctg
     4141 tatattcaat taacggttca tggaatagat cttctatttt tccagtaaaa aaataatgaa
     4201 ctaaaatcag aatatctcga atgtctccta aagaatacaa agtcaaattt tgcaatgaat
     4261 tatagagtcg ttctctatca gccattgcaa cattcaaatt gttcattttt agtttaaaaa
     4321 aaactttatc aatattattt gctctaaatg gaccaaataa gtaatatctg gttttaaaca
     4381 tgtatagaag aaacatctca ttaaaatcac cagtaaagaa atggaaatct ttagtttttt
     4441 taatattatc agttagtaac tttttataat cataaaaaaa ataagtagtt ctatctgagc
     4501 gatactcttt tataatactg aattcggaat taaaaaccac gataggtaac tttaaacaaa
     4561 catgaagaga ctttaataag acttctttat ctgaaaacac ttttgtttct ctctttcctt
     4621 tctacatcat taaatagtat tttatacgtt atctaaaata ctattcctct gtcaaaataa
     4681 gctaacttac ttcattataa aatatccact tatcgctttc atgtatattc caccgtaaaa
     4741 agtacatttt atcaccgaga actcatcatt tttcatcatg atgaatacta tttacatata
     4801 tctagttcaa agacaataat tattatgatc cgttattatc taagcactat acagataata
     4861 ggaatttttc gtttctaaat attccaattt gggaatccaa taaaaatttt cgttcaaata
     4921 cgtgtctatt cgaactcttt tctagttgtt aattatgaag ggggaagaaa taaaaaatac
     4981 aatctataca cgaataagaa tattatccaa aaggaggttt tagaaaagat ttattatacg
     5041 taaaaagctc aagacatttt cttagccata aggacatgtt tgatatttaa gaagatatat
     5101 gaattttctt ttctaagtat aaagataact atccattatc aactaaaaaa acatttttga
     5161 aaataaacat cagcagtcct atcaatgcat gtgagcttat agaagttatt cgcagcgcag
     5221 cataattgca ttagcttctt ttcgtgtttt ttgcctcttt tccctttaaa tcttaatgga
     5281 ggaggtgtgc aatatgtcag ataacgacga acgcgtaaat gcccagttga ttcgattctt
     5341 tgaaaaggtc attttgaaca ccgctaatac ttattataaa aaacaagaag aaattcaaaa
     5401 acatgaacaa cttgatcaac tcccaccata tttgtttact aaagatacta taaaatttaa
     5461 acaaccgatt aatgttttaa atgtgactct ccttgttgaa gatataaaat tagcaaaaat
     5521 ccttcctttg ttgaaagaac ctgaacaaat ttttcttatc gaaaaattta tctttgataa
     5581 aactgataaa gaaattggaa aggttctggg gattacaaga cagggtgcga caaatttaaa
     5641 acatcgactt tacaaaaaaa ttcaaaaaat gctggtttaa tatctgcata ataactaatt
     5701 ttgtatgctt ctttgctcgt tctcctcctt cccaaagaaa tagattataa gtccatggga
     5761 agaaggtaga tttatgaatt ctttaaaaga agatttcatt ttagcaaagg ctggaaatga
     5821 agaagctgtt gaggcaattc tcaaaagatt tagctctttg attcataagc aatcctggag
     5881 aactggaaaa tatgatcaag attgttatca agaatgtatg cttgcaatat atctagctat
     5941 ctcgaaattc gaaattaaag aataactcaa ctaagggagt ctgtgacata agtaaaaaga
     6001 tagtttcaaa tttcgaacaa taaatttgaa actatcttct ttataattat aaagtatcga
     6061 ttttacagcg ttctataatg attcatagaa tctaaaacga atgattttaa ttatcaacgt
     6121 tttttaattc gtttttagct taaaaataac ttttgtcaca gtctcactcc taaaattact
     6181 ttatttacgt atgaagtggg caggaggtcg aatccagaac tgggctatgg tacttcaacg
     6241 aggacttctc ctctagaatt gaaaagcatg cgatttacct tccgtaacga cggtagattt
     6301 attcaactat gtgtccaatc aaaatttgtc tgatttcaaa aatagtcaag agaattttgg
     6361 ttgttaaaaa ctcttatcta tcaacttcca cagtttagtt gacaaaccct gatactaagt
     6421 tgggctatga tacacttttc ttgactatca gttacgttac cggaaggaat gaactctatt
     6481 gagaaaaaca tatgatcgta aatttaaact aaagatttca caggatatcc ttgagaaaaa
     6541 agtaactacc aagaaaattg ctgaagaata caatatctct cgtccaacaa tttcccgatg
     6601 ggtttcagaa tatcgtcgat acgggaaaaa tgcttttgct ggacaaggaa aaagattacc
     6661 tgataaagca gatttctaca ttcttgaaca ggaaaataaa cgactaaaag aggaagacga
     6721 gtgttctacg aacacaaaga tcgatacgga tctccaggga tcactcaaaa actttacgat
     6781 gaaggaatcg aaatcaataa acgtgttgta gctgttctta tgcgtgaaat gaatttatgc
     6841 acaagaggat ttcatcgacg caaatcttct catggtagag aaaaaacaat caaagaaatg
     6901 gtaaaaaaat gttgaatcga taatttgaac agaaccaaat tgatgctgtt tgggtgatgg
     6961 atattactta cattccatgt aatgacggtc gcctctattt gtccacctat attgacttag
     7021 caactcgtat tctacgttac tatatggtag attcacacat aaaaaaagag attgtcgtcc
     7081 gtccattaca aatttattaa ggagaattgc ctacggtaat tcattccgat agaggtagcc
     7141 agcatcggtc ttttatttat caagagctgt tgaacgacca ccacatcaca cattcagtga
     7201 gccaaactgg gactcctgtt gacaatgcag taattgaagc gtttcatcga tcaatcaaat
     7261 gagaattaat cgactccaac aaatataaaa gtaaaataga gatgaaggtg ttaatccaag
     7321 attatttaga agactactac ccaaacaaaa gaatccatac aaaatttatg atgactcctt
     7381 gacaatttga agcgaagaaa ataagggatc tataatatct agtgttggtg acgccttctg
     7441 ttgccaatac tttttctttt ttctaataaa cgcaaacaga caccttaaaa tcctttagaa
     7501 taaagtcgac aaaaaccatt caaagtagtg tttcaagatg tcctattcag agtttaccaa
     7561 agagttacta gatattctag acctaaatct tacctttcat gaggatgcct ttcgcaaaga
     7621 gcgcatcaat gacgaaacat gttttgcttt tgatggcaca ttgacctatc aaccggagga
     7681 atgctttcat cgccactatc aaaatgaaca aacgatcatt aaatagggct ggaaaaaagt
     7741 atccatctta ttgaatgatg tcagtaacta caagaccatt ctgcggatta acaaacagcg
     7801 cttcaaatgt aaacactgtg gaaagacttt tttagcagaa gattcagtta gtgatcgtcg
     7861 ctgctccatt gctcgcagag tcaaacaagc cattcttgag ctattaagcg aacctctttc
     7921 tatgtctttg atcgcacgta tgaagcacat ttctccgacc actgtcattc gaatacttcg
     7981 cagccttcgg cctaaaacca tttctttgag ccagctgtta ccagaagtgg tgtgtttcga
     8041 tgaattcaaa tcagtgaaaa atgtctcggg agccatgagc tttgtcatga tggacggcaa
     8101 gacccatcaa ctgattgata ttgtggaaaa tcggcaactc aatcctttac gcgactattt
     8161 cttgcgctac cctataaaag tccgtgaaca agtgcgtcta gtggtttcag atttctatac
     8221 accctatcgc acattggtga aagagtgttt tccgaatgcc cgaatcgtcg ccgatcgctt
     8281 tcatattagc caacacattg gtcgggcttt taccaaccac cgaattcaag taatgaagac
     8341 ctttaaaaaa ggggatcgtc ggtcgaagca cttaaagaaa tactggaaac tacttcaaaa
     8401 gaatgcgtgg gaattgaaag gtcagcatcg ctactggcgt ccgtcatttc gagatcatct
     8461 gacagaagca gagatagtcg atcggctatt atcttatgat gattccttaa agcgaggcta
     8521 cgaagtctac caggattttc tttccgttat cagaagacaa gatgttcctg aattcgtcgc
     8581 gctcctaaaa gaagactaca aggagttgcc agagcactac caaccagtgt tcacgacctt
     8641 caagaaatac caaacagaaa tcaaacgagc gttgcgcgtt ccctattcca acggccctat
     8701 agaatgtttg aataaccata tcaaagtact aaaacgaatt gcctatggct atagaaactt
     8761 tcaaaactac cgagaacgaa tctttttata tcgaggaaaa tattttaaga aaactaagaa
     8821 tactacccaa ctgactaaag ccagaacaac aacacggcta gacaagatag ctgtctagcc
     8881 gtgtgagtat ctcgattatt ctattgaatt tcttcaccaa cactcattga cgaagagcca
     8941 aaataagtaa tctaaccgac tgttaactaa accattgcag gtcccgttaa agatacttgt
     9001 gcctgttgtc accgcttctt tttcttgtcc acaagcgctt aacacactta ataaagcccc
     9061 tgctattatt aataataata tctttttctt attaaaaacc tcctcatcta tttccagatt
     9121 agtaaatgta gtaatctgtg ctttcttttt tctcaatact aataactaac ttatggggta
     9181 aacaaatact cgtttgaccg ggttttgaga tccatccagt tctaaccgcg atttgatcag
     9241 gactattatc ttctttaact cgaattcttc catctttaat ctcaacaata ttatattgtc
     9301 ccttcgcagg atgataattc acgagtttat gattgatctt atccaaatcg aagcgatcca
     9361 tttccttgcc atcaattcga acgatggcat atttgatagc atcttcagtt gtttcattct
     9421 ccttttctat agagaataca aataagggaa taaaagaggt aataatcaaa atgccaataa
     9481 ttatgacatc gcctatcttg acaccagctt ttcttaaaaa tttcattaac gatatctggc
     9541 taaacatatt agactttttc catggaaatg gtgaaatttt tcggaaatta tctgcattaa
     9601 gagaatcagt taaacaaccc tcaagttgtt ccttaataca ttgttgatcc atcttcatac
     9661 caataaaaac tagtttatta atgcgttcac caaacaacgg atgccaggct tccttcaatt
     9721 cgggattttt ttgtataatc atttgacact caattttagg taaactagct acccaataat
     9781 ttaatgattc aatactttta tagctacccg atgtttcaaa gatcgtcgaa aaatcactat
     9841 gttgggcaaa ccaaagaaac ccttttgctc ttgtaatatt gccaggaaaa tttttatccg
     9901 taagatgggc aaatttttgt gcgtcaagga gtaaccgatt tcgatagata aaacttgaga
     9961 taccatattc ttctgtttca ggaatatgat tttgatagcc aagctctaac tctttgaacc
    10021 agcccactga ataggaagtc tcatctatat taaaaagatt tgtatttaga attttcgata
    10081 agtctacttc acctttaatt gtcctaatta ttttggcatt ggactgtaac ttagcaatta
    10141 gaccgttaat tttgtaaatc gtcttggttg acactaagtc actattattt aaaagtaata
    10201 tgttacaaca ctcgaattga tcaattaaca agccacgaat atcctgttct tcttcaacta
    10261 cattaccttc agcttttctt tcctgaatct tttcacccgt ttcgaaatta tcccaaaaac
    10321 gttttacatc cactactata ataatggcac caatctctaa tcgttgggtc aaatcaatgt
    10381 ctaaagggtt tttagctaat ataattgctt gaataattgg aattggtttg ctgattcctg
    10441 aagcttcaat aacaatttga ttcaagtcag aaaattgcac taattgatct agttcaacaa
    10501 tcaaatcttc gcgtaatgta caacaaatgc atccattcgg catcgaaaca agtttttctc
    10561 cagttctttt aaaacctttc ttgtcgacta ataccccatc aacatttact tcccctatgt
    10621 catttacaat gacagcaatt tcctttccgt gatcaccgta cagaatatga tttagaagta
    10681 tcgtttttcc tgaaccaaga tagccagtta agattgtaat aggtattttt ttcataggga
    10741 acctctttct ataccttgaa tttacacttt aagtgcaaca cataaaaatg agtcataatc
    10801 gatatccaac tagtataagt ttgtcgagaa cactcctaga aggaaaataa ttatgagcca
    10861 gtatcgtcat cttactatac tcgaacgaga aagaatcttt ctgcttcacg aagaaggatt
    10921 ttctattagt ataattggca acgacattca gcatagcccg tttactattt tacatgaact
    10981 gagaagaaac aagaaaaaaa ctattcacct tccaaagcgg aaaaaaatta tgcttatcga
    11041 agaaaaaaat gcggacgtta tcacattcta aatgatccgt gagtttggtc aattgttcgt
    11101 catttatttg tcgattttca gtggtcgcca gaggaaatct cgaatcgttt gaagcatgaa
    11161 catatggact tttcaattag ttttatcacg atctaacgtg caatttgcaa tgatcttttc
    11221 gatacagaac ccctctcaca cggcaataaa ggcctgatcc gttcattgca ccatcgagga
    11281 aaaacaagac atacaaaaaa tcatgtcgag tctcgtggaa agatttgcct tactcattcg
    11341 atccatggcc gtccaaaatc cgcagatgat agaagtgatt ttggtcattg gaaagccgat
    11401 attgtagctg gcaaaactgg tggtacttgt ttagtgactt tgacagacag aaaatcatgc
    11461 ttccttttag caggaaagaa ggtccccaga aagaaagccg cttatgtgag cgagaaaatg
    11521 attgaacttt taagcagtat tccaaatgag gcggtcaaaa cgatcactcc agatagagga
    11581 aaagaattct ccaatcattt cgcagttaca gaagcattga ataatatgcc cttttatttt
    11641 ccagatcctc atgcccttgg caacaatgaa caaattaaaa tacgaataga ctcattcgag
    11701 aatacttgcc aaaatcgaaa gagatagcta cggtagataa ctcaacgata aatcagatga
    11761 ttgaaaaact gaataacaga cctagaaagt gtttagattg gagaacacct tatgaagtct
    11821 tctttgataa agtgttgcgc ttgatttgac aattcaagac ataataaaaa gcagatcaaa
    11881 tccaaataag ggaaaaatga tctactctgg tattatcaat taattggcca agctattatg
    11941 ccgttttgct aaacgtctac ttcttccagt attgaccttg ataaaacaac aatcaggatc
    12001 ccgttttaat actctatgaa ctgtgtcaat actaacatgt aaagttgcag caatatcagc
    12061 taatgtactc ccatttaatc tcatttgctt tgcaaatcga taacgccgat aagcatcaat
    12121 attcttggaa tccatagaca ataatacttt tcttaccatg tatttcctcc aaaaattgaa
    12181 ttttaatgag ccatcatttc ttgagcaatt tcatgtttag acaatgaagc tggatagaaa
    12241 gtaggccaat tatgcaattc attatagagt ttttcttgac tttctccacc aaagaaaata
    12301 tggaaatgct ctgccttact tggtgcaatt ccatgatcac taaattgaat atatttaaaa
    12361 cgaccagcac ctgcatcatc agtttcaaaa ttaaaacgaa caccacggtt tcctttttca
    12421 taattcaaaa ttttgtatcc aacatatttg tatgtgtatt gatgatgttc accgttgact
    12481 acaaaatcaa tggtgttgtc tttaatgttg atagtatcaa tatctgtctt atagccagta
    12541 gtataataat ctttgtactc ggcagctgtc atgtctttat tgatttttgc tttgtaatcg
    12601 aaaacttcat ccaaaattcc atcttttaac aacggataaa cagattgcca ttcgcctgta
    12661 taatcactca attcgcgatc cttcacatcg gcatctttaa agtacccatt agcaactgtc
    12721 ttttcatcct tcgcttcttt ttctggaact acctcttcac cagcaaccat agttgttttt
    12781 tctaacgctt ttagattgtc ttccattact gaaacataat cttcaccatt atccatttgt
    12841 tcttttgtaa gactttcaag aggattcagt acttccaatt ttatcccagc ttcgttggcc
    12901 aaagtttttg caattttatc attagcattc ttttcaaagt aaatataatt gatcttattt
    12961 tttttaacat actcttttaa ttcagctaat cgaccagaag atggctcttc ttcaggactt
    13021 agtccagcaa taggaacttg tttcaatcca taatccaaag ctaaatatcc aaaggctgcg
    13081 tgttgcgtca caaaactttt ttgtttcgct tctttaagac tagtggtata gtcagcatcc
    13141 aaccgtttca gtttagtcaa atacttttca gcatttgtct caaatacttt tgcttttttc
    13201 ggatacaatt taactaactg atccttgata tttgaaactt ccttaattgc cattttgggt
    13261 gaaacccacg tatgaggatc tagttcatga tggtgatctt cttctccgtg atcatgatct
    13321 tcttcttcac tacctggcaa taaaatcatg tcttttgttc cttctactac attaggccca
    13381 gctttcttcc aactttcttt agcttttggt acccatgatt ccatgttttc gttatgatat
    13441 acaaaaacat cagcatcatg agcttttgcc atatccttag ctgagggctc atagtcatga
    13501 ggttctgatc ccgctggaac cattaaatcc acgttcgctt catcgccgac gatgtttttg
    13561 gtgaaatcat acattggata gaatgttgtt acaatttcta attttccatc tttatcattc
    13621 gatacttttg catcattagt gctggagcaa gctcccaata atcctagagc tgctatccca
    13681 ataagtccta cactgatttt cttcattctt tttccttcct taattatgct aatttcttca
    13741 ttttatttcg tttatgttct ttgataattt ttaatgccct ttttctagtt ttaatattcg
    13801 ggcttttaag tcgtcgatat gcactagata tatccgtttt ctccattaga aattaccccc
    13861 aatcactact tatcattatt tgctttccgc cagtaattta tcaaaactct gtttgatcct
    13921 ttcttcatcc aacatttttc cgattagaat aatagtggtt tggtcttttt gtcgagtggt
    13981 gtattgaaaa ttaacctgtt cgtttacctc ttgcatggca actataaaat cctgctcttg
    14041 taaagcaatc aatcctttaa aacgatacag gctcccttgg ttggttaaaa tcagccagtc
    14101 aatccattgg agtaaaaaat ctttttttat gtcttgatct gaagttaaga gaattgattt
    14161 aaactcatgt acttgatggt gttgatgata gtatttgcca ttatagtgat tttctgatga
    14221 atcactttca aaaactaagg gatgattaaa ttttttcaaa ttataaaaat cctttttttg
    14281 aatcgtttca ctatgtgtga acattcgaat atcggataaa gggttaatac ttttgatttc
    14341 tctctgtaat ttttttagtg cagataaatt caagttttgt tttctagaca caaaaatgcg
    14401 atctgccatg acaagttgct taagggcttg tggttctctt tcaataagtt caaaactgtc
    14461 actatcaata acagtcaata aactatcgat atatactctt cctcttagtt gaggcgctgt
    14521 taaaagtgtt tgaatgattg gttggggatc tgctatacct gtagtttcaa tgatgatttg
    14581 tgaaattggt tgttgatgtt cttctattgt ttccagtaaa gaaatcaata ttgctaataa
    14641 atcactgcga agactgcaac acatacatcc attatttagt tgtaacaccc gttcctcgct
    14701 atgaactaat aatttgtgat caatcccaac ttcaccaaac tcattttcaa ttataataat
    14761 ttcttccctg gggtagggtg agacttgcaa ggcttgattg attagcgttg tttttccagc
    14821 ccctaaaaac ccagaaacga ttgtaactgg tatgcccatt ttgtcacctt tttaccactt
    14881 agctatttca cttctttaaa aattgcccgt ctgcgcaatt ttggcgaata cttttttaat
    14941 tctaaccgtt cagggttatt ccgtttattt ttgctggtga gatacagacg ttctccagtt
    15001 tcgacacatt ccaaaataat attttgacgc ataaatcttc ctccttcaat acttatcgat
    15061 cttcaagata tgcttgaatt tgttgtgcat cttcaaaagt taactcgcca gattccaatt
    15121 gtgaaactaa attttctttc atatcaacag gtatctccca ataaccatcg atacattgaa
    15181 ataactcctc gtcatactct tcaaaaattg gatagattct taaaaaatca tcaaatgata
    15241 agccttggtc ctcatagtaa tctttgacta atccattttc aattgcctgt tgggtcggta
    15301 aacccgtttc agtaataatt cctctctcta ccatcgaacg ataaaaagtg catttatcta
    15361 gcgattgctg ggtcgtttca agataatact ttaatccttc ttcaactaaa ggtgggtaaa
    15421 taatttccat tttgattccc tcctaaaagt tatatattaa actattttga agctccttta
    15481 attactttct ttccattata gtaccctttt aaagatacat gatggctacg tctataatca
    15541 ccattcgctt cgtcaaatga aatttctggt tttactacag tttgatgagt tcttcttaac
    15601 cgtttcttcg ccttagatgt ttttcttgct ggtactgcca tgatatttcc tccttttacc
    15661 aacttgcttt ttttactcca ggaatcaacc cttgatgggc aagttctcta aacttaatac
    15721 gggacatacc gaactttcgc atataccctc ttggacgacc atccgtctga tcacgaagcc
    15781 tcagacgatt cggatttgaa tctcttggca atttagcgag agcggtgcga tctcctgcgg
    15841 cttttaattc ctgacgttta tctgcatact tttcaatcat cgccatttgt ttctttgctt
    15901 tagcaatttt cgactttttt gccatatacc tttatactcc ttttattttg atttagacac
    15961 ctcaaatcgt aatcgttacg ttttgacact gatactttac caacaagagt tgctcttgtc
    16021 aacaataaat aacatgaaat aaaactcata tgaatagata actatttgaa aacgaattta
    16081 tcggtacata gagataatca aatcatttaa aagaatatgc agtttaggct ctgaaaaata
    16141 agaattcact tttattagtc caatcaaaca caaataccgt tttaagtagc ttttcctcta
    16201 cttaaaacgg caatatgaaa gaaactataa ctttttattc aatcttttat gtttaactgg
    16261 tttatcgcca attttttaaa actttgatta ttccttatat tataagaata gacattaagt
    16321 gaactaattc aatcatactg attctttcgt gtattcaaaa ttagatgctg tttaataaaa
    16381 ttattctttt tgaaaaagaa ttataactat atcccaaaaa ttgtaggtta atttaaagcc
    16441 tatttcatca tcgtgattga gcttcttttt catagacgaa tttctcagat agtttagttt
    16501 tctttatgag atttttgtat atttctgacc ttcgatacaa ctcattatga gtaccttgat
    16561 caactagttt tccttgatcc atcactacaa ttttatttac cttttcaata gacttcaagc
    16621 gatgcgatat aattagtact gtcttatctt gtattaaacg atttaaactt tcctgaatac
    16681 gtttttcatt ttccgcatct aaactggcag taatttcatc taaaattaaa attggcgcat
    16741 ttttcaaaaa agcccgtgct atggataggc gttgtcgctc tcctccagaa agtgaacttc
    16801 cgttttctcc gaccaatgta tgataaccgt caggtagttt ttcaataaag tcttcgcagt
    16861 tagctaaacg agctgctttt ttcacttcct catctgacgc ttgactattt ccaatacgta
    16921 tattttccaa aatacttgta ttaaacaaag ttacctcttg aaaaacaata gcgattttgc
    16981 taaacaaaga agctggagat acacgtttaa tatcataccc atcaattaaa atacagcctt
    17041 catcataatc atacagtcta gacactaatt tcaagatact agttttcccg gaaccactag
    17101 cacctactaa cgcagtcact tctccttgtt tagccgtaaa agagatatga tctaaaattg
    17161 gggtattgtt atcatatgag aaagagacat ctcgcaactc aatgtcaaaa gatttcagag
    17221 gactatctga tccctcttgg atactggttt ccttcatagc tctaattcgc tgtattttag
    17281 gagctaaata aaatatttca agcactgctt ctttcataga atcgaaggaa tcctttattt
    17341 ttattgcggc tagtaagtaa ccaacgacgt agagtatagt cacttcaccc gttaacagta
    17401 agtgaacacc tactagaatg actactgcta aactaacata tgagaaaata gaggataagg
    17461 ccatgactga aaaagtactt aattctacct ttaaatgaat cctttcactc tcttccattt
    17521 ttttgaaaag tctgtcttga acttttttag atagattaaa gctattaatc tcttgctgca
    17581 attcaatagt ttcttgaaat tcttccgagt tttctctcaa agtatcgtaa tatttagtat
    17641 tggctttcgt ttgggatttc tttgataaca agattaagac aaaactaaat aacgttggca
    17701 aaataacagc taatcccatt ttgacattac caaccaaaag catcactgaa ataaaaggga
    17761 aaaacagagc cataccgccg gctttaggta ttgcatgact catcgcatgc tcaatacctt
    17821 caacgtcaga catgatagtt tgagataaat ctgataaatt atgttttgaa aaataggata
    17881 atggtaaatt tgacaaatcg tctgcaattt gcactcttaa atgcgcactt tctttataag
    17941 tactattata taagttttca tactccctat ctaacaacca atacatgaaa agcaaagtaa
    18001 caaacgatac tgcaaaataa agccaacggg gctttgcatt ttctaaaact aattcgtcta
    18061 tcagcatcat tataatgaat gctggtacca tattaatgca gtatacaaaa aaactagaaa
    18121 tagaagcttt agttaaagct tctgcgccct gatcagttaa agcaaatttt tttttataaa
    18181 aatttttcat tgtcaagcct ccaatcattt gcattctcat aattagtgac caattgttta
    18241 tacactcgat gtttagccat taattcatta tgatttccac gttctactat ttttccttct
    18301 gacaagacaa gaatttcatc tacagattta atgctggata atcgatgagc tatcataata
    18361 actgtttttt ctttcatcaa atattgaaaa gccttttgta gttcatactc attatctgga
    18421 tcaatagatg cactggcttc atccataata acaatctttg catcttttaa aattgctctg
    18481 gcaatagcta tacgttgttt ttctcctcct gacagataaa ctcctttact accaattaag
    18541 gtatgctctc tttcgggaaa tttttctaaa atcgattcgc aaccggctaa tcttagcgcg
    18601 tcaaatactt tacttgctgg cgcttgagga tttgctatag aaacgttatc gtaaatactc
    18661 tgattgaata gtttcgtatc ttgaaagaca aaagcaattg tgttaataat tgtgtctttt
    18721 gaatagtgat ttaaaggctt accaccaatt ttaatctgtc ccttatccac attgtagaaa
    18781 cctgaaatta gtttagctat cgtactcttt ccgcttcctg attttcctac taatgcataa
    18841 attctttttt gttctaaaac taagttgaaa ttttctaaaa cacactcttc tttgtatgaa
    18901 aagctgacat tttcaaatgc aatgtcacaa tttttaatct gtgtctcgtt cccatatttt
    18961 agttggtctt gcttcatttc taaataaagg gagtctagtg tttcgactgc atatcttgct
    19021 tcaaacaagt gcatacttac atacattatt ctcatgaaag aaacaaaaat aattccactt
    19081 aaaaaaaaca acatcaacaa gtcaacagct aagatcttgg gagtggtaag agaagttata
    19141 aaaaaggtta taggaactat caaaatgcaa actatgccaa aaaatagcca ttgaaaaaga
    19201 acaaaaggtg ttttcccact caaagaatac ttatatgcaa acttagcata atcgttaatt
    19261 gctttattca aggctttaaa tgatgttact ttagcaccaa atatctttat aacttgaatt
    19321 ccgcggatat attctaccgt ttcagagctt aacacatcta acgattcttg atatttttga
    19381 ataaaatttg tattctctgt cattttcttt aacaagaata caccaattac taacatggcg
    19441 attagaacca atccaatttt aaagttaatg aaaaagccta aggcaactga taaaacaggt
    19501 gttactatgg cttgagcact atctggaatc aagtgagcaa ttgccatatg tgttttagcc
    19561 gcgttgtcat caattgtctt tcgaatatat cccgaagaat ttaaatcaaa aaaacgaaaa
    19621 cttgcttctg ttaaaccgct aattcccttt tttctcaaat tagtctctaa gcgaaaccca
    19681 aggatatgag aaaataagcc agaaaaaata taaaataaag ctcctaaagt taaccaagca
    19741 acagtttgaa ccgcataact cttagctaaa tattcatctc ctacaataat tagagactga
    19801 agaaatttgt aaatactgta atatccatag actgttaata cgacagaaaa atcagaaaat
    19861 aaagtggcta accatccgta gtatttcatt ttagggacat aactaaataa ttttttgtat
    19921 actttcattt tttcctcccc cgcattcaat ttcttctctt attcgtttac aactgttaat
    19981 gctttccgta atagcgtaaa ttagagatgt acaaacagat agaaggtaaa ctacgttcta
    20041 ttttttgtat ttttttaaga cttttcttcc aatcaataca ccaatcatag ataaacttgc
    20101 tacaactaac actgaaataa ttccccatat acccaccgcg tagtggatca ttgcatccat
    20161 tgttgcagca gattgtcctc tatctatcca gtcttgacga aaacgatctg taaagaacca
    20221 tatgggaatc cactgtccgg cagcactgcc tagttgcatt agaacccaag acacaacttg
    20281 aggaattgct cgatcatatc caaatacaga tagaataata tcagctaaga tcgccatact
    20341 aatcgaactg ataaaccaag gtaagtacgc cccgcccatt aacgtaaaaa ataacaataa
    20401 aacaattgtg taaatagtaa aaattccttt tctagggtag ttatagctaa tataaacaaa
    20461 tatgattcca gataataatc caaaaatccc tggggatatg ctgtgaccaa acgccccacc
    20521 aatactacta accattattg aaaaaaagta aattactagg gaaataactg tagctaaacc
    20581 aataaaaata taatcttttg ttttcatata tattctcctc aattctattt cgttatgtca
    20641 ttaaaaatct gttctatcaa agttgaatct tctactctaa gttttatatc tttttttatt
    20701 ccaccatttt ttaaataaat aattctattg catgttttat aaagaaattc cggatcatga
    20761 gtggctataa ctactgcacc cttttctttt aagtctttaa taaggtcagc aatcctttcc
    20821 atattgatat aatccaaccc acttgtaggt tcatcaaata gaaataaatt agtttttgac
    20881 aatgaagcta tagaaaccaa taatctttgt ttttctccac cggataaatc aaacggtaat
    20941 tgatctttca ttttataaag ttccattttt tttaaaattt tttcttgctg atctttacta
    21001 actatttcat tccccagggc taactcgctc ctcactgatt ctgtgaaaaa ttggtaatcc
    21061 atttcttgca ttactaaaaa cggcgatgac aaattttttt tattttcgat tatctttcct
    21121 ttggtagggc gaataatctt catgagtatt cttagtaagg ttgttttccc cacaccgttt
    21181 ttccctacca aaccaataac atctccaact ttgacatcaa aatttatgtc ttttagaata
    21241 ttttcataag taatttcttc aacttttaat acatctgcac ttaccttttc gatataggga
    21301 acttcaatcg aactattaaa aatgtcaaat ttccttaatg cgttattgtt ttcagttttt
    21361 aacaactgaa tagttgtagt ttttacagtt ctatttttaa caaatagaac ttgatcaatt
    21421 aattctttca aatagtaaaa acgatgttca gctataacaa tagtaaatcc tttatttttt
    21481 aaatcacaaa gtaagtcagc aagtttctta gtcgctttga agtccaaatt tgaagacggt
    21541 tcatccaata taattaattt agagtttagc gataaactac atccaataga aattttctgc
    21601 cgttcaccac ttgatagcga aaaaatgttt ttatctaata tatttgaaag atctaataat
    21661 tcagctaatt cattgattct tttatccata tgctcttttg taaatccaaa gttttccatc
    21721 gaaaatacta actcactcgt tgtatttgtt gtaaagaatt gtcctctagg attttgactt
    21781 acgtagccaa tattttttga tatactttct tgtgttaagg attgtagcga gttattttca
    21841 aataaaattt ccccaaccaa ttttccgtca taaagtcttg gaataagtcc attcattaac
    21901 tttaatagtg tggatttccc actcccagaa gaaccagtaa tcaatgtaag actgcctttt
    21961 tttattgaaa aattaaggtc aacaagcgct tgttccttaa catccttata tgaaaaagaa
    22021 acattgttaa attcaaacaa ttctttcacc tcaaatcaaa atacttaaga aaaaaatagt
    22081 aacggaaaac aggatgatat agtctaataa gctcatgttt gttttatagt aagaacttct
    22141 tttcacagga gattctatcc cctttgttat tgcattagcg gtcatttctt cagcaatcat
    22201 agttgcacgt ataagaacgg gaactaacag aaattccaaa tattgcagag gctgaaaaaa
    22261 agacaagcga atgtttctca tttttaaaga ttctttaatc attcttattt cagaacgata
    22321 agtcggaaag aatctgatca ctactgtaat acttaacatt atttttttcg gtaaatgtat
    22381 tttttctaaa gaggataata attcattgct agtatagaca ctaaccaaca accatgagat
    22441 cattacgacc ggcaacattc gaaatacaat atataaggat gtcccaaaaa atatagtaaa
    22501 aaactctatc ttgatagcat caataatttt cattactaaa aacagaactg aataaatcaa
    22561 gatgaaataa atacatgtct ttattttacg aaacatcaat actaaaactg tagcaataat
    22621 gaaacacccc acttgaaata tatttccctt tcctaaaaaa ataatgaccg gaaaaaaata
    22681 tttaaagtaa tcaaggttaa cggattgatt tttgacactc tttcacctcc aaaaaataag
    22741 atcgcactgt tatcttaagc tgacaaaaat gcaccgttat tcagataaca gtgcgatctt
    22801 atcaaaaagc ataactgaga acaattctca atgcaagctt ttttttaatt aactcagtaa
    22861 ttcaatccac ccaggaacag aaaattgata caatcttctg gttaatagca tagtcttttc
    22921 ttttgaatag ctatgcttca atatatcata gaatgtagcg tagaatgagt aaatgtagaa
    22981 gtggatttct tcttcattaa agactaaatt ttgattgatc attccgatag tctttaactt
    23041 atctagacaa cagactgtct tttttgtcac aaatgatgta attttttcaa caatatcttg
    23101 atatttggtt ccagctgatt ggaataaaac caaatcgaat atacgtttat tctcaaaaat
    23161 ataattaata aatggatcta attcattgaa gttctctctc caacttttct ctatatctat
    23221 attttctaag tttaagaggt atttggtaaa ctcttcatta tacatattaa taagcgcatt
    23281 aatatgcggc tgaataattt cttcaaataa cgcttcctta gaagtaaaat gtttataaaa
    23341 agcacccgta gttacgcctg cggtcaagca cagttgcctt atcttagttt gctgaaatcc
    23401 ttctttttca aaatggctta gtccactttc tattaatttt tggtgagttg taatataatc
    23461 tctggtttct atgggtactt cctcctaata agatgaatta actatattat cttacacagg
    23521 acttgaagtt tcaatcgtta acgtctatta ctgaactcat tccttagagc taaactaatg
    23581 agaaagagca aaataactga tacaaaaagc aatcctacaa gaattaatag actcatctaa
    23641 atcattcacc ttttctaaaa taatccgaga aagatttaaa aaaattatat ccagctatta
    23701 gggtaagtcc tatcataatc actccaatag ccattttctt atcctcccta aaaataaagt
    23761 cttttactta aaaccttttt tgtaatcgtc aataaatttt ttccctttat cagttaattg
    23821 aaatcctata tctaaatagt cctcatatct aagtttagcc agcatctcac ttacagatgc
    23881 tggactaaca cttagaactt ttgctaaatc attatttttt aatttctttt ttctttttga
    23941 taattcctga attgctagta aataaattag tatagtagtc gttttaattt gtaccatacc
    24001 taccctccaa attatttcga aaggccttca gcaattttat ccaggttcca tttcatcatc
    24061 gcatagtaac tatcaccatc ttgtcctttt tctgcaattg aatcagtaaa aatcgttgaa
    24121 tagataggaa tattggtatc ttttgatact gttttcattg gtctatcgtc cacactgctt
    24181 tctacgaata aggagggaac ttttgttgtg cgtaattttt caactaagtg ttttatttga
    24241 tctggtgttc cttcttcttc agtgttgatt tcccaaatgt aagcagaagg cacattatac
    24301 gctttcgaga aatatttaaa gcatccttca cttgtaacaa tcattttttt atcattcgga
    24361 attgaagcaa atttagattt agcttctttg tctagagaat ccaatttttc aatatactta
    24421 tctagatttt ctttatagaa ttttttatta tcaggatctt tttccgctaa ctgtttttca
    24481 atatttttag cgtaaataat accgttttct aaatttaacc aagcatgggg atcttccttc
    24541 cctttctcac tctgaccctc taagtaaata acatctatgc catcacttgc tgcaaaatag
    24601 tctttgtttt cctctttgtt cgcatttttt actaattttg taaaccaagc atttcctcca
    24661 gtttccaagt taacaccgtt ataaaaaatc aaatctgctt ttgaagtttt ttgaacatct
    24721 tcaggcaaag gttcatattc gtggggatct ttcccaatag gtacgatact gtgtaaatca
    24781 attttatctt ttgctatatt ttcagtaata tctgctaaaa tcgaattagt aactactacc
    24841 tttaattttt cgttcgaagc cactgtatct ttgtctttac tatttgttga acatgccccg
    24901 aatataaaaa gagcaatcaa aatccccaga cttcccagta ctgctttcca ttttctcatc
    24961 ataactttct ctccttcttt cttaaaaatt tttgttttgg tgagattaga aaactaatta
    25021 caaataagaa tgccgctgtt aaaacaatac ttgatcctgc tgctatgtta aaactataac
    25081 caatgaacaa acctagcaat gatgagcacg ctccgactgt cgccgaaata aatatcatag
    25141 tttttaagct gtttgcatat aaatatgctg tagcagctgg tgtaattaac attgcaacaa
    25201 ttaatatagt tcccacactt tgcatagctg ttactgctac taaagttaat agaatcatta
    25261 atagataatg ataaaaactg acattcatcc ccattgcttt tgccattaat ggatcaaaag
    25321 aagtgattaa taattcttta aaaaatagaa caactgtaac caacactaaa acagaaacgc
    25381 caattgtaat ccacttatca atatcttgta cagctaaaat atttccaaat aagatatgaa
    25441 ataaatccgt tgagctattt gcaactccta taaggataac tcctaatgct aaaaaagaac
    25501 tgaaagtaat accaattgct gtatctcctt ttattacact attgcttttt ataaaagtaa
    25561 taatgataga agctaataga ccaaatacaa tcgcaccaat aaaaaaatta atacctaaaa
    25621 tataagaaat tgctactcct ggcaaaacag catgagaaat agcatcaccc ataagagaca
    25681 ttcctcttaa aataataaaa caacctactg ttccagaaac aatccctata actacagatg
    25741 taattagagc attctgtaaa aagtgaaagt catacagacc attaataaaa ttttgaagca
    25801 tattattccc ccttgtatat tagagttagg gttttaacct tccggttttg attggataac
    25861 cctatgaacc atcgttattt taatttggta ttaactcatt tcttttgaga taatatattt
    25921 attggattga gaggctaagc cgttcccccc ttgggccatt gaacccgcac tcgagagact
    25981 ggctcctctc tctgataagt ggattgcgta tgagttagat gttgaaagtc cttactttac
    26041 tccgtatctc gtacaaggta gtgacgcttt tcagttgagt ggatttcaat ccaaaattct
    26101 ttttttgaaa ggtcagatat acatgtactt tttaggcatt gatatcggta aacgcactca
    26161 cgttgcttct atcatgaacg aggaaggaaa ggtattacta aaaggttttt catttcctaa
    26221 caccactgaa ggagcagagt cattaattga gcgaatggtc gactattccg gagcacccag
    26281 tgactttgtt atagggatgg aagccacggg gcactattgg ctgtccatct tttcatacct
    26341 tcacgaatca gattatttga ttcacgttgt gaatcccctt caaacagacg gatggcgtaa
    26401 aggtacagaa atacggaaac gaaaaaacga tattattgat tctgttttga ttgctgactt
    26461 aatgcgctat ggctcatttg tcgaaacggt cttatccgat gaaaatgttt tttctttgaa
    26521 acaactttct cgttaccgaa cttatttagt aggtacagcg agcgacttca aaagaaaaat
    26581 tatagccgta ttggatcaag tctttccaga atacgcgacg atttttacca agcagggcgt
    26641 tttcggaaaa gcttctaaag agttattgct ggcgtttagt gccccgatcg acttagaaaa
    26701 catttcctca gaaactttgg cccaatactt agctgagtta agcaggaacc gaatcaaggc
    26761 agaaaaagcg gaccaattga agcaagcagc ttctaactcc tttggagtaa aatttgctca
    26821 agaagcgttc accttccaac tacgttcaat gattgaacaa ttaaaattca ttgaaagcca
    26881 aataaaggaa acggaaagag aaatcaagca cataatggac actttaaatt ctgttattct
    26941 cacaattcct ggaattggtc ctataaacgg tgcgactatt cttggtgaga tcggagatat
    27001 tcaaaaattt tctaacccga aaaaactcgt tgcttacgct gggatagacg cttccgtgac
    27061 acaatcaggg caatatgagg caacgcataa tgttatgagt aaacgagggt ctccatattt
    27121 gcgaaaagcc ttgttttcgg cggctttagt agcttctcaa tgtgatcctg tttttagtgc
    27181 gttttaccag aaaaaagttt ccgaaggaaa acatcatcta actgccttag gtgcggtttc
    27241 tcgtaagctt tgttacgtga ttcatgctat tttgactaaa aacgagcctt atataattgt
    27301 ttctgattag ctattgaaca ttcaaaaaaa ctaatggtaa gaagcttatt tgttgtaccc
    27361 ttttttcgga attatctgtt ataaaatatt ttttgatttg gctaattttt acttgactct
    27421 atatagttag tctctcttct atcactttcc ttttttcaca cgactcccgg tttctttgat
    27481 aaatctcgat actttcaatt ttcttgaatt tttcatttga ggtacacata gatacagacg
    27541 atttcttgct ctagtcatcg caacataaaa tagtcttcgt tcttcttcta tcgtcgttac
    27601 tggttctgct tttatttcat taaagtcgat tactttcttt tctgtcgctc cgttataagg
    27661 caaacttcct tcgttacaac caatcaaaaa gacatttcgg taactaagac ctttactttt
    27721 gtgaatgctc tggatacata gtgcatcaag ttttccttgt ctgtaagcaa tcaagcgggt
    27781 ttttaattct ttagctgtcg cttgggtttc ttgcgataag gcttggagtc ttctgaaagt
    27841 agcatgctgc tttacttctt ctcgtatcca ttcttgatca ctctggtcga tttccttagc
    27901 tatacgtggc agatgaagat agctttgaac aagcgaatag atttcttgat gctggtctgt
    27961 tttacgcaac gcttcctcaa actctcggat ttctgcagat ttcgatttta aattggggct
    28021 tatcgacaaa atataatctg caacggatat attttgatat ttaggagaaa agtattgatc
    28081 gcattcactt tttttcaggt agcagtctgc catcagctgc cggagcaatt gctggtaggc
    28141 ctgatttttc ttttgcagat tcagtgctgt ttgccaatga acaatttttt gatagaaatg
    28201 ttggaaagac ttgataccaa agataccttc atatggacta tctgcttcca gtacaaaagg
    28261 aatattcgtt ttcagcagag attggacaag ctgctgcgtt tgtgaagctg atcggtataa
    28321 tatgattgat tccttatatt tcccattttt ttgaataaat gtctgaattt gtttgattag
    28381 ccactgactt tctgctttag tatcagaaaa caaataggct tccataacac ctgcttcttt
    28441 ttgtgctgga atcatcgcct ttggtatccg atcattttta ttatagctga tcaatctatt
    28501 tgctccttgg acaatagctg cccgagaacg ataattagtt aataagaaaa gagttttggt
    28561 aggatattct ttttcaaagt tcttgatgta tgctggctct gatcctctga atccatagat
    28621 actctgatca tcatctccaa caacaatcaa cttgatcctg ttttcctttg tcatccgttt
    28681 cacgatttcc cattgaagtg gattagtatc ttgaaattca tcaatgaata gataatcata
    28741 tttttggccg atataatgct ggatctcctc attctccaaa gcgcttttca gattttggag
    28801 tacatcattg aactctagca attgctggct tcttttttgt tcttggagtt ccgtgagcaa
    28861 tccatacagt cgttctgata tcggctgtcg tgcattctta tcaatggaat catatttttc
    28921 tttaactaac tgaaccattt cttctactga aaggttcata ttctgccaat agtctaaccg
    28981 agaagcaatc gttttttctc catattgatc aaatatataa agattatatt tacgtatcag
    29041 ctgttgcaaa acagcattca ctttttgtgc agtatccttt gaaaagtctc cttgtattcc
    29101 ttgcattgct acttcaggaa attttcgaca aatttcattg tatatcctaa aaaagatact
    29161 atggaatgtt ccgatatgga cagcggtttt tctctggctg aaattatcta ctcgtttttt
    29221 tagttcattt gcagcgttcc ttgtaaaagt gatcattagt atgcgttctt cgtctacttg
    29281 tttttgcgtc atcagataaa cagcttttgc acagattgtt tgcgttttgc cgctcccagc
    29341 tcctgctatg attcgaagat gtttcttcat atcatatgtg atagctgctt tttgttcttg
    29401 attgaagcga ttataggaac gtttctccat cattttaaag aaagagctgt ttccttcact
    29461 ttcttttact tgtacttctt cctcaataag tccgggtgct tcgccataag ccgcttcata
    29521 ggtagcaatg atttcttctt gtagccgaaa gacttgttga agctttttat acttgttctc
    29581 ccagcgtttc aattcttttt gtaatcggag aatttctttt tcattcaact gattgatttc
    29641 cttcccatct ttcttctttg aatttgttta tttcaagttg gttatttaaa gtttcgttgt
    29701 ctattttttc tttatactaa cagacctttc taaaaatgaa aatgggaagc gatatgattt
    29761 tagttttctg aaaatttttc ctttttttca atcgtttatg ctaagataag gaagacaaaa
    29821 atattcataa aaggtgatga aaaaaatgca gacttccttt cacgaggggc gtacaatagg
    29881 acttttgctg acatttatcg gaggagccat ggacagttat acttatatcc aatatggtgc
    29941 ttttgcctct gctcaaactg gcaatatcat tctatcgatc atccaagcat ttgacggaga
    30001 atggctaagt gttggtaaaa aagtattgtc tacccttttc tttttcttag ggattcttct
    30061 aacaaagtat ctaattgatt attttagaaa aaaagaaaaa catttctggc gcttgtttgt
    30121 tctatattat gaagcagtga tttttttctt tgttagtttg acacccgtcc atgagcatcc
    30181 cgcattagta acgattttga ttgcttttac tgcatcgatc cagtgggtag cttttgataa
    30241 aatcaacggg cgtgcctaca ctaatttatt tacaactgga aatttaaaag gggtagcaac
    30301 gaacttatat gattattgta tttctaaaga aaaagcagat tttgatcgat ttttccacta
    30361 tctaagtgtc gttcttgcct ttatcgcagg agctattgtc cttgttttct gtcatcatct
    30421 gtttggcgcc cattcgattt tgatcgtttc cattttattt ttgatcatgg ccctcactca
    30481 gacatttcat ttatggcaat tttatcatac gaatcggttc actatttgat ctcaatgaat
    30541 caaaaaaact aagcaagatg ctgctcacag agaaatatct gcgagtgagc aatttgctta
    30601 gtttttatat tatttagttg taaagattcc ctttgctttc gggttatttg tagtgtagcg
    30661 gatcgactgg gcatctgcct cttctgtcat tttctttgcc cgcatcttga tttcttgtac
    30721 gatttgttct ccacatgccg gatcggctac gaaatcatat ttgtccccat cgatcactat
    30781 tttgggacat atatcaaact gttcatacca ctcttcgtat cgtcgattga gttctttata
    30841 gtaggaatag agttcaggat cttgttctag ctgttcatat tcccggcctc tttttttgat
    30901 tctcgctaac atagtttcaa aggatacacg aatataaacc agtagatctg gtttcttttg
    30961 tggcgaaatt tcttctaact ccttcagcat cgtttctaaa agaccttcat actgctttac
    31021 ttctacttca gaaacacgcc ctaaatctgc attcaaatga aacagcatac tatcttcgta
    31081 gatggagcgg tctagtacgt tgtcatcatg gctgaaagca tctttgattg ccaaaaagcg
    31141 tttgttcaaa aagaaaatct gtaataaaaa agtatacttt tctggattag aataaaatag
    31201 cggcaatact tcattatctt ccacgttctc ataaaaaggt tttgtttcta aatcttgggc
    31261 aagcatttca gttagtgtgc ttttccctgc accgatcgtt cctgcaacaa tgatcacaat
    31321 tatcggcatc cttcctgtaa taaaatctgt tcttcatttt actacttcat ttatagaaat
    31381 aaaagccttg actttatctg ctccttaaaa gctacttctc taaaagtagc caaaagtaac
    31441 tcctattcat gaaaataaag gctgtgacaa aagtcttgtc gcagcccttt tttcaaataa
    31501 acagtattct cctgccaaca cctcggtcac aaggcaatat tcataaaaca tgaaaagctg
    31561 ttttttaaca ttattccttg taactcagag ctaaacggga gactcacaac ctctttatgc
    31621 tctcaacatt ttatctgttt ttattcttct attgtacttg atttgcgtac aactaactgc
    31681 cagtgcagat tatgagcggt atcattgtct tctactgcgc atttcatgac acgtatcatc
    31741 acactatttt catagatttt ttctattttt ccttttattg gtgattcaaa taaatcagat
    31801 ttaaatgcat atgtttcgcc gacttcaaac aattgttcat tttccataag aatccctcca
    31861 tcacctttta taaggtcagt aattttttaa cataaatcac tcgaaaaagc acaaacttgt
    31921 cataaaaagt acttttcgta tcaaaactgt cacttttttt ggtaaggttc ttggaaaacg
    31981 aagatttttt taggagatca tgacggtttt gatgtcaaaa ccacttttta tgaaacaaaa
    32041 gacgtttttt atttttttta gcataaaatt tgtggtggag gtacgtatga gatgaaagat
    32101 aaagttgtga acaaattatt agaagcctta ttcagcggag acaaatcgga agaagatatg
    32161 gtgtatgtcc aagtaaaatt tgtcttagaa gttttattga ataatcttgg aaaactagcg
    32221 gtcgttctag tcttttctct ggtgacaggc tcatgggcgg aaacaggaat cacctttctt
    32281 tcttatatct gcatccgcag atatgcttat ggattgcatt ccgactctga attcgtttgt
    32341 ctgctgtgga cactacttta tttatggggc gttcccttgg tgatgaaaca tctgcaattg
    32401 actatctcct tcccaatgat ggtctttttg ttaatcagct gctttttgtt actgcttcgc
    32461 tatggatcaa gaggtacagc aatcaatccc attgaacccg agaaacgtcc cccattatta
    32521 aagaaggcga tcagcatgtt tctaattttt tctctcatta cgttattttt ctcagcttct
    32581 tacttttcta cctatttgct acttgggatt gttttagaaa tagctacgtt gcttcctatt
    32641 acaaactact tgatgaattt tggaggaatc tttcatgaaa aaaacaatca ttaaacaatt
    32701 aactaactta tctgactttt ttgtatctgg ctgctgcttt ggtatgagtt ctgaattcaa
    32761 aatccctgaa aaattaaaaa aataatacgc caattgtgct ataatttggt aaaaatcaat
    32821 gggagctgta ctttatgttt ttatggtcca tagcgttgca atatttgatt tacacaattt
    32881 gtatcttatt gattgaccat cacatccgat acaaatatct gtttgcggga gtcattctga
    32941 tttcttgtat tttgattgga tgggtctatt cgattttagg gatttttact gctctaattg
    33001 ctataggaat gctgatgctt acttttttct tcttttcgac ttcgcgtcaa caattggttt
    33061 acgcgcttcc ttttgggtta ttgacgtcgc ttttaggaga tcacttaaca agcatcggcg
    33121 atttttttgt tttgaaatct tcggttattg aaccaggaga ttcattgcag tattttcaca
    33181 ttgtcttatc cgctttttta tctgctttat tagctttttg tttaaaaaaa tcgttagaga
    33241 cttggtttca cactgtggac cgccgtatga tcggtacgat cgggacattg atattattta
    33301 catactatat cattattttt tatacccgtt tttctggtga aacacctgat gtcttagctt
    33361 tgaatacgag ttttttcatt ctatatctgt gtgttggcct gatcatcttg gtttattatt
    33421 ggaaaatctc taataagaaa ttagctgatc agttattaga gcaacaagtc aggatgcaac
    33481 aggattatat caaagatcta gaaaaaaact atcaagactt gagagaattc aaacatgatt
    33541 accaaaatct gcttttttct cttcacagct atatttcaga aggcgactta gaaggattac
    33601 ggtcttatta tgatcaaacg atattaccta cacgccagat gatgaacctt tttccggcca
    33661 atctaagtat gttggataat atgaaagttc ctgagatccg tagtttactg tcattaaaac
    33721 tcatgatggc acaggaaaaa gggttgatcg tccagcttca ttttcctgag ccaatcgaac
    33781 tggatacgaa acatacggta aaccttgtac gtatgcttgg tattatcttg gacaatgcga
    33841 ttgaaggagc tagtgctgca aagaagaaaa aaatcgaatt gaccatactc aagaagaatc
    33901 attccgtgat gattcgtgtg atcaatacaa caacaaatac attaccgtta aaccagttga
    33961 aacaaaaagg gttctcaaca aaaacaaatc caaaaaacga aggccttggc ttgtttatct
    34021 tggatgaatt gacaaagacc aatccttatc ttttccttga aacatcaatt gaaaaccagc
    34081 gtttttctca aacgatttat atacaaataa aataaaggag taatgatatg attcccattt
    34141 atatttgtga agacgatcca aaacaattag aagttttatc aacggtgatc aaaaatagaa
    34201 tcatgattga aaacttagac agttatgtcc atatttctac ctctgatccg gaagaacttc
    34261 tcaatgcagc caagatcaga acttcttctt ttggtattta ctttttagat atcgaactag
    34321 aagacagtga aatggatggt gtagcgatcg gtaaattgat ccgtgaatta gatcctttag
    34381 gaaaaataat ctatgtgact tcccatacgg aaatgtcgat gaaaatctta aaaagcaaca
    34441 tcgaaccgac tgattatatc gtcaaagaag atctttatga tttaaaagaa aatgtcgagc
    34501 atatcctgag caaaattttc gaagattttc aaatgtccca aatccaaaaa gatatcttca
    34561 aaatagagtt taatgatgag atcaaatttt taccgatcaa agacatccaa tatttttcta
    34621 cttcgctagg agcgccacat aaactggaag tccatttgac tcatgcccaa ttacaattct
    34681 atgagaagat caaagaaatc gagaaaatgc atcggaattt tatccgttgt cataaatcct
    34741 atgttatcaa tacacaaaat gtgcggtcga ttaataaaaa aaccagagaa gtcacgttgg
    34801 caaacggcga gaccatccca gcctctatcc gtggattaaa gaaattgatt tcataaaaag
    34861 aaccgaatag tttggaccga ctaaatgacc agccgatcca aacccttcgg ttcttttttg
    34921 cctatcagtg caaaagcatt tcctgtgcaa tttcacgtcc atccattgta tctggataaa
    34981 atgttggcca attctccatt tctttcagca atacttcttg actttcattt cctgcatata
    35041 aatgaaaatg ttcggagtca gccggtgcaa tcgtgtgatc actgaattga atatatctaa
    35101 aagcgccact ttccttatct tctgcttcga atagatacct tacgccacgg tttcctgcct
    35161 cgtaggtcaa gatttctttc cctacataac gataatttga acgtttcgtt gttccattct
    35221 taaacgtaaa tgccatctct ttctcactga tcttgattga agcaatatct gtttgatagc
    35281 ccttcgtata atattcttta tattcttgtg ctgtcttatc ctgattcaat ttttctttat
    35341 attcaaaaac aggatcaaaa gtcccatctt ctacatacgt atctactgtt tgccaagttc
    35401 ctgcccaatc tgaaagagag cgatcttgta catcctcgtc ttcaaaataa ccgttgtaga
    35461 cgctcttttc ttttttgggg gtcaaagtat cttctagcgg gttttctgtc tctgtcgttt
    35521 ttttcaacgc ttcgaggttt gcttccatga tagaaagata gttttctcca ttttctattt
    35581 gttcattcgt caatccttcc aaaggattca atacttctaa agatacacct gcttcgtttg
    35641 ctaacgttct ggcaatacta tctttggcgt tttcttcaaa ataaatatag ttgattccat
    35701 gttctttaac aaagtgtttc agttcagcaa ttctcgccgc agacggttct tcactagaag
    35761 aaagaccagc aatcgatact tgattcaatc catattctaa cgctagatag ttgaatgcag
    35821 catgttgcgt gacaaaagat ctttgttttg cttgcttaaa ggtttcttga taaagctgat
    35881 ggagtgcttg aagtttctcg gtataggctg ctgcattttt tgtccatact tcctgttttt
    35941 ctgggtaagc ttcaatcagc tgatcacgta tgtttgctac ctgcttgatt gctaaacttg
    36001 gagctagcca tacatgtggg tctagctcat gtgtatggcc ttcttccccg tgttcatggt
    36061 catgatcatg tccttcttca cttcccggaa gtaaaagcat accttctgtc gcttttatcg
    36121 tatggacatt gccttcttgt aatgtttttt ggattgcggg gacccatgtt tccatgtttt
    36181 catcattata aacaaagata tctgtatctt ggatctttgc catgtcttta gcagaaggtt
    36241 cataatcgtg ggaatcagtc cctgctggaa tcaataactc tacttctcct tcatccccga
    36301 cgattgcttt tgtaaaatca tacatgggat aaaaggtcgt catcacgctc aatttttctt
    36361 tactgtcctc ggctttccca cttgccccgc aagcagttaa catacctgct aaaaccagca
    36421 tggccaatat acctatcaat cgtttcattt atgacactcc tcttctcatc ttctttcatt
    36481 tgaatgttcc gattcgcttt tcgcaaaccg taatagttac gttttagcaa caggatttaa
    36541 tttatcatat ggttaaaaga actgtcaagc gttttcttat tttaattgat gagaaagttt
    36601 atatgaatga ttgacgatat ttttgcaatc aacctctatc attttccttt tatacccgct
    36661 tttgtctata atgaagttat agataaagga ggaaaaagag tgaaaaaaga aacagataca
    36721 acgaatcgtt tgatccgctt tttaggagga aaaacctctt actatgtttt aggaatagtt
    36781 atcttacttg cgctgatcat ttattttttc catcagatct cgtttatatt caagcctgtc
    36841 ggaatcatta tcgctactat cttgccccca ttattgtttg cactgatctt gtattatctt
    36901 ttggaaccag tcatcaaacg tttgagcaag cacctttcga ggaacttgtc agtcattatc
    36961 gtttatgtga ttattttatt tttattgggg cttggaagca tatggcttat tccttttctt
    37021 gaagaacagg caaagacatt gatcagtagt ttgccagatt tgtttcaaga ttttcaagag
    37081 agtctccgac aatttttgga gaaaacacct tttgccgatt catttaatca atttttcgct
    37141 tctattgacg acgtgacgtc tgatatagct ggatttattg gaaattattg ggaaagtggc
    37201 gcacaacgga tcagcaacat tttttcaact gttacagcta tttttattac tttatttact
    37261 ggtccaattg tcgctttttt ccttttgaga gatcctcaaa aattttatca gtcagtttta
    37321 gcgattgtcc caccagcatt tcgtacagat tttaaaaatt tgacaaagat tgctaatcaa
    37381 caattgggtt catttctaaa ggggcaaatc attgcttcat ttatccttgg agcagtctac
    37441 tgggtttgtt tcttactgat cggattagaa tttgctagtg ttttagctat ttctgctggg
    37501 ttgttatgta tcattccata tattgggccg tttatcgcct tctttccagg tttgatcatt
    37561 gcattccaag actctacttt tatggctgtc aaatttgtca ttgtctggtt tgccgtacaa
    37621 cttctccacg gtgacttggt gattcctcga gtaatgggtg atcgtttaca gatccatccg
    37681 attacgatct taatcgtttt acttgtcatg ggtgatctaa tgggaattgt gggcgttatt
    37741 tttggtattc ctatctatac gttagtcaaa ttactcgtta cttttatttt ccgtaaattc
    37801 aaacaacgct acaataaatt ttatggcgat aaaggagagt atgaaaactc ttcattttct
    37861 gaagaagatt attttaaata aaacacaaaa cgtcgatctt acgagaatag ctcgtaggaa
    37921 cgacgttttg tgtttttgtt ttaatttttc agcaaagcaa ttgcctggta tggttttagc
    37981 tccagacttt gatgaagaac agtatcggaa taattatcga taagaatatt ggcttctgtg
    38041 aatccttctg ggatggcgat ccttgtatct ttatcataga aatttgttaa tacaagcagc
    38101 tgctgtcctt caaattggcg aagaaagcca taaacttccg gatgatttgc ttcataagca
    38161 tgataatctc cttgtgcaac gattggatat gtttttctca gccgaatcaa tttcttgtaa
    38221 taggacaaaa tagaatcttc agaagatagt tctttttcta cattaatctc ttctagcttg
    38281 cctccaactt ttaaccaagg tttccctgta gtaaatcctg cttgttctgt gtctgaccat
    38341 tgcatgggtg ttcgagagtt atcgcgagat tttgctttga tccgacgaaa cgcttctttt
    38401 tctgtgaatc cttgttcaag gagtaactta taagcattca aactttctac gtcaatatag
    38461 tcggaaatcg atgaatagtc tgggtcgatc atgccgattt cttctcccat ataaatatag
    38521 ggcgtcccac ggttcaaatg gatcatggtt gctagcatct ctgctccttg ttttcgatac
    38581 tgatcgatag ctacaaatcg attgagcgca cgtggctgat catgattatt aaaaaataga
    38641 gcattccagc cgttaccctc actcatcttt tctccccatg tatgaaatag tcgctttaat
    38701 tctgcaaaat caaatggagg agtagaccat ttattcccat tttcataatc gactttcaaa
    38761 tgatggaaat taaagaccat tgataattct tctctactag gttctgtata caagatacaa
    38821 ttttcgatcg tcgtagagct catttcaccg actgtgatga tagtggaatc cgtcccaaac
    38881 gttgcttggt tcaattcttt tagatacgta tgggtgattg gtttgtccgt atattcaggt
    38941 ttgccatcat tttctttatt atttttcaat tgttcgtctt taccgataac attgataaca
    39001 tcgaaacgga atccttttac ccctttttcc atccaaaaac gaacaacttt gaatagttcc
    39061 tctcttactg cttggttccg ccagttcaag tcagcttgtg tccgatcata taagtgcaaa
    39121 taatatttcc ccgtatctcc aaatggcgac caagcacttc caccaaattt tgatacccaa
    39181 tccgttggct cttctcttaa aatgaagaag tcctgataat gctggtcccc tgctagtgct
    39241 tttttgaacc attcatgttc tgtcgaaacg tgattcagca ccatatcgag catgatttct
    39301 atccggtatt tctttgcttc ggctattagc tgttcgaatt cctccatcgt accaaagata
    39361 ggatcgatgg ctgtgtaatc agagatatca taaccgttgt ctttttgagg gcttggataa
    39421 atagggttta gccaaatcat gtcgatgcct agatcattca gatacgggag tttttctttg
    39481 attcctttta aatctccaat tccatcacca ttactgtctt tgtaagattt gggatagatt
    39541 tggtaaatga ctttgtcttt aaatgtcatg gatatttacc tccattcaac tgatttatta
    39601 cctaccacaa cttatatata caagttatca tttattatta taactgaacc gaaagcgttt
    39661 gtaaaattta tctttataca ttctaagagg tctgttgccc aataaaaaac aagagatcag
    39721 acatgtattt gtctatcctc ttgtttaaaa tagcaaaata ttcttgtttc ttctataaat
    39781 ggtgttcaaa agcttttatc tacggcaatc agtcttctca aatgtaaaac atgaggagct
    39841 aattttattt gagtattctt tttgctcgat gcaggacggc ttttttacaa cctctgattc
    39901 atggtgttca atcagctgtc cttcggtatt agctcaaaaa acggcaaaat atgaaaaact
    39961 attttgccgt ttgtttctct aatactcagg tcaaaccgct gatttcacaa cctctgtttt
    40021 tattcattcg atttcaacgc atcaatcata tcgatatgct ttaatttgaa atgggtaaca
    40081 atcatcacaa taaccgtaaa tacgatagtt aatcctgctg ataagacata agcccaccat
    40141 gtgatcacta atggaaagat gacattctcc atagacgctt gttgcaagat gaagtcagtc
    40201 aatatatatc ctacaccaaa tcctccgatg attcctaaaa gagtaaagat gatattttct
    40261 cgaacaatgt acatcgtgac ttctttatca aaaaatccaa ggacttttat tgtagataat
    40321 tcgcgtacac gctcggaaat attgatatta gttagattat acaagacgat aaaagccagc
    40381 agtcctgata atacgacaaa gattaagaca accgagtcta agttcgccat tgattcttct
    40441 tgcgtttcga tttgtttgga catgaaagac gtatttgtca cagcgtctgt ggcaagcagt
    40501 ttctcggaaa gcatttcttc ttcttttgtt gtcatcttat ctgtacgcag caaaaatgca
    40561 ttatccatca tcgattgatc agtaactgaa gcataatatt caggggacat ataaataaag
    40621 ctacctagat agtttttcac gatttctttt acttcgactt tccattcttt ttgatcttca
    40681 tcataaagcg aaatatgatc tcctgtagat aagtcaaata gttctgctac tttttgcgta
    40741 atagcgattc ctgttttagg caaggagcgt gggttctctt caagatcagt taaatggata
    40801 aaacgatcca aatcagctgt tttacttggt acgatcactg tcagactttg cgaagcatgt
    40861 cctttttttc tcaattctac ggtttgagta tgaatagcta ggatctcatt tactttttct
    40921 tgcttctgca gcatatccgc tgctttttga cgactatctt ccgtggatga atccaatgta
    40981 acgattgctt gatagtcaat gatcgttcca aattgtttgg ctgaaacaga acttagagaa
    41041 tctttcaatc ccacgcctgc aaccatcagc ccggcacatc cagcaattcc gataatcgcc
    41101 ataagcattc ttgacttata tcggaagaga tttcggtaac tgattttttg attaaagcta
    41161 aggcgtgacc acagcggagt gatgtattca agaaaaatgc gtttccctgg cttcggtgct
    41221 ttcggttgaa gcaatgcagc aggccgttct cttaaatctt tgaataaaac gatcattgca
    41281 gcgccaaatg cggcaatgaa gaatgcggca gctgcttgta aaatcggcgg ccagtcataa
    41341 aaaataagcg cactcccaat atcataccgc tcgttagaca gctcaaaaat gatccttggc
    41401 aaaagattcg ttcctaatat cgttcctaaa acaataccta tccctgaggc tagacttgca
    41461 tagattgcat atttttttgc gatttcaact ttcgtataac ctaacgcctt taatgtcccg
    41521 atttccctgc ggttttcttc taccatacgt gtcattgtcg taaaggtgat caatgcggca
    41581 ataaagaaaa agaaaacagg aaaaacattg gcaatcgcag cgatacgatc agacagatca
    41641 ccaaattctt gaaaaccgac attttctgaa cgttcattgt ataggtatga tggtttagtt
    41701 aaattttcaa ttttttctgc atttcgattc aattcttcct ctgcagaggc cagttcacgt
    41761 tctttctcaa ctaattgcct ttcttgttca gcaagttgag cttcttgttg agataatgtt
    41821 tgaacagcga ttgttcgttg cgcttcagga agctgctgga tagttgctga ctgttgcgct
    41881 aactgttttt tagcatcttc taaccgtgtt cttgcttgcg ttgtttgtgc tttgccatcc
    41941 gctatttttt gctgtgccgg ttctaattct tcgttggccg attttttcag ctcttctaag
    42001 cgttcttcgg gtcgatcttg taaatacttt tctgcctttt cttgattttg ctccatttta
    42061 tctttgtaag ctttgctgta cgtattcaaa ttctttacgt ttgtaaaatc aagatataag
    42121 acagaataaa tatctgtttt aaaaacggat tcaggtaaat agacaaaata atcgacgcta
    42181 ccatttccga cgttcgcgta tcctctctcc aaattgttga tgaacaatgg agaacggaca
    42241 aagcccgtga tggtatactc tttttctttc aattcatctg aatcaatctg ataaatatca
    42301 ccgattttat acccttcatc ttccgctttt tcatccaata caagctggtt tggtttttcc
    42361 gggagttttc catcagttaa ttgtagcttg ttctgcttgt tatttttgtt ataagaaaat
    42421 atttgaatca cttcgttttt gccagtattg gaataataga tctgttttcc tgtttctact
    42481 tttgcatctg ggatcttttc tgcttgagca atatcttttt gtgtcaagcc accagtagaa
    42541 acgatttgca aatcagaaag tcctgctgta ccaacatagt gatccatcgt tttttgcatg
    42601 acaggtccag cagttttgac acctacaaat aaaagtgttc ctagcatgac aataaggatg
    42661 attgcaatga atcgtccttt agattgccga atttcgcgaa aacctgcttt aagatatgtt
    42721 cttgttttca taaaatcccc ctaccataca atctcatcaa tggatgaagg atgatcattt
    42781 aattcaacag accttacttt agcatcatta atgtgaatga ctctatcagc gatgggcgct
    42841 aaagcagaat tatgtgtaat gatcaaaacg gtattgccgt gttgtctgct agcgttttgc
    42901 aataatttca atacttgctt gcccgtttca aaatccagcg cgcctgtcgg ttcatcacat
    42961 aaaagaagtt tgggattttt agctagtgca cgagcaattg aaaccctctg ctgttcgcct
    43021 cctgataatt gggacggaaa gttattcaat cgatgagcta ggcccacttg cctcaatacc
    43081 tctacaggat caagcgcatc aggagaaact tccgttgcca attccacatt ttcttttgct
    43141 gttagattag gaacgagatt gtagaattgg aaaacgaacc ctacatctgt tcgtcggtaa
    43201 gcagtaagct gtttatctga aaattgcgca atatctgtgt catcaataat gatctgacct
    43261 tcatcaggtg tatccatccc acctaaaata ttaagaatcg ttgactttcc tgctccactt
    43321 ggaccaagta taatcactaa ttcgcctttt tcaattgaaa aagaaatatc gtcatttgct
    43381 gtaatggtcg tttctcccat tttgtatcgt ttgtattcat tttttacttc gacatacttc
    43441 actctgattc ctccattttc acgatatttc tcgctatatc tatgcatcga atgcgttttc
    43501 tcacacttat ttattttacc actgaatttc tctagactaa agaaaggaat cctttaattt
    43561 agttgacaaa taaacgattt atgatttact tacataaaaa acattgttat ttgaaagaag
    43621 gaacatcatg aatgatttaa aggaaaatat gatttttgat ttatcaaaaa ctgcttttgt
    43681 cgcgatcgac atgcaaaaag agatcgtaaa taacggtaca ctctctccac acactgcagc
    43741 atctattctg acaaacaatg atttgttagt aagaacattg aaacgtaccg ctgccttgaa
    43801 agttttagtg aacgtagaca tctccacttt cccttatttg agtcaacaaa ctgatatggg
    43861 tggaatgact gcttctgtac ctccagaatt cactgattta cttttgaagg attctttgaa
    43921 agatacagat aatatgttga ctatcacaaa atacaatcca agtgcttttt ttggtacttc
    43981 tcttgatctt caacttcgcc ggcgtggaat cgaaactatc attttaagcg gtgtagcgac
    44041 aacaaacggt gtatatgcta ctgcattaga tgcctttcaa cacgggtacc atatcgtgct
    44101 tgctgaagat gcttgcagtg atcgtgacaa agaatcccat caattgttca taaaaaagat
    44161 atttccgaaa actgcacgag tacgctcaac gaaacaaata atcgaagcta tccaacaaag
    44221 caaataagta ctggcacacg tgattttcat ttacttcttt ttgatttcat gggaaaataa
    44281 ccacaggatt tagataggag tatgaacatg gtgaaaaaaa agatcacaat caaagaagtc
    44341 gctaaacttt ccggcgtttc aatcacaact gtctccttga tattaaatgg aaatacggag
    44401 aaattcagtc cgaaaactgt tcagaaagtt ttagctgcca aagaagaatt aggctatcag
    44461 cctgactatt ttgctagaca aatgattacc aaggaaacga aaacaattgg tgtactcgtt
    44521 cctgatatca cgaatccatt cttcagtaca ctgatgcgag gaattgagga tatcttgtat
    44581 aagcagaatt tcgtcacgat attatgtaat gctgattctg atcatcaaaa agaaatcgaa
    44641 tatctagccg agctcacacg tcgaggtgtg gatggattca ttatcgcgac ttctgctgtc
    44701 tctacagatg caatcaacga aaatttgaaa aaacaaggcc ggcccttcat tgttttggat
    44761 cagaaaaaat ctgaaggatt tagtgatgcc gtacgaacag acgattttcg cggtggttac
    44821 ctagcgggca tgcacttgct tagtctagga catcaaacga tcgcccttgt ctatcctgaa
    44881 aatccaccgg aaaatgtcca cgctcggatt gaggggttta aatctgctct tgatgtttac
    44941 caaatccctc acgaccaact gatcctctta cctacacagt tctcaaaaca aggtggctac
    45001 cagatcacag cagaacttct tgattctgct gcaactggtg tgtttgcttt aaatgatgaa
    45061 ttagcttttg gattatatcg cggattagag gaagctggaa aaagcatccc tgaagactac
    45121 agcattattg gctatgataa tatagatatg tgcgagtata tcaagccgaa actgacaacg
    45181 atcgcacaac caatcttcga attgggacaa acatctgcca agttattgtt agatcggatc
    45241 caattcccag aaaaagaatg ggaagaaaaa agattacctg tacgattaga aaaaagattt
    45301 tcaactgcac ccttgaaata gctttcaagg tgtgctatat ttttatcgaa ctattaaaac
    45361 gttttactaa aacgttttaa aaaataattt tcccatcaaa ataaatgaga tagttggagg
    45421 tttgtaaaat gaacacggtt acagtaattg gaagtattaa tatggacact acccttcgtt
    45481 taaccaacat gcccaagcca ggcgaaacga tgcatgcgca tgagattttt cacgctggcg
    45541 gaggtaaagg tgccaaccaa gcagtggcag ccaaacgttc aggcgcacgg acatctttta
    45601 ttggaggcgt tggggctgac agcgaaggac aacagttatt agatctactg acaaaagaaa
    45661 acatcgatac atctgggata gctgaaatcc aaggcgccac aaccggacaa gcaatgatta
    45721 tggtagacgc agcaggagaa aatagtatct tgatccatgc aggggcaaat aatgctttcc
    45781 atgaacaaga agtcctaaaa aacaagcaac tgattacaaa cagtgacttt attattgctc
    45841 agtttgaaag tagcttagat gcgacgatcc tagctttttc tattgcaaaa gacgcaggaa
    45901 aaacaacgat cctgaatcct gcaccagctc gtgaaacgat tcctactgaa ctacttgaaa
    45961 agacagatat cattatacca aatgaaacag aaacagaaat cattacagga atcagagtga
    46021 cagatcataa cagtttggtc gcagcagccg aaaaactcca tgaattaggt attggaacag
    46081 taatcattac actaggcagt gccggcgctt tctatcatac agaaaaagaa cacggtatcg
    46141 tccctgcttt taaagtggat gccgttgaca caacagccgc aggtgataca tttattggcg
    46201 cattaagcag cacacttcag ccagacctta gtaacttgaa agaagcgatc ctttatggaa
    46261 atctagcctc ttctgttgct gtgcagtctt atggtgcgca accttctatc ccttaccgcg
    46321 aagctttaga acaatcagca gtctaaaatt aacaatgaga ggaagaaaca aacatgaaaa
    46381 aaggaaaagt aatcaattca gatatttcac gagtaatcgc acaaatgggg cactttgata
    46441 aattaagtat cggggatgca ggcatgcctg tcccctttgg tactgaaaaa atagatttgg
    46501 ctgtctcaaa cggtcttcca agttttttat ctgttttaga aaacgtttta gaagaacttg
    46561 aggtacaatc gattgaattg gcggaagaaa taaagacaat gaacccggaa atattggaaa
    46621 aaatcaaatt attgttacca gatacaccga ttagctttat cccacatgaa gaaatgaaaa
    46681 aagagttgaa taactgtcat gcatttattc gtacaggcga aatgacacct tacgccaata
    46741 ttatattagt gagtggagtg gtcttctaat ggaaacgaca atgaatcctg aacagatggt
    46801 actgtccgag cagattcata tgctgattga acagttggga ggaaaagaca atattgattc
    46861 tgtccttcca tgtgcgactc ggcttcgtat caaattgaaa aaacagccag tagccaatgc
    46921 agaaaaatta aaacagcaaa tcccttccat taagtatttc attttactcg atagatatgc
    46981 agaaataatc atggatcagg gattggctcc tgcttacaag gaattgacgc gtcaaatcga
    47041 tcattcagct ccgaaagaaa agctaaatcc gatcgaaaaa ctatttggtt tgatatcgga
    47101 aatctttacg ccgatcattc cgctgtttgc cggttctggt atattaaaag gtctggttgt
    47161 tttagcgact acgattggct ggcttagtga aacaagcgga acttatcata ttttgtctgc
    47221 tgcgtcgaat gccgtctttt attttctgcc aatctttctt gctttttctg ctgccaaaac
    47281 gtttaaagtg aatggatata ttgcggctgt cattgctgca gcactgattg aaccgaatct
    47341 gacctcttta ctttcagaca gtggcaaagc agctactgat tttctgggga ttcctgtagt
    47401 actgatgcag tatacgtcta ctgtcatgcc ggcgatttta ggtattttct tttattcttt
    47461 tgttgaaaaa ttcctcaaaa aatatattcg cgaaaatatg caattagtat ttgtaccttt
    47521 actttcatta gttatcacgg ttcctttgac gttaatggta ttcgggcctg cgggtgttta
    47581 ccttggcgaa ggtttagctg ccgcaattac ttggatgatg gatattaacg gaccgatcag
    47641 tggcgcaatc atcgctggtg gttggaatat tttggtaata tttggtatcc aatgggctgt
    47701 aaaccctgtc atgatcagta atatctctgc ttatgggttc gaccgaatcg ttccgttgac
    47761 aggagcagcc aattttggaa tggctggtgc agctttaggt gtatttctgc gaagtaaacg
    47821 ttcaaaaacc cgttcgatct ccggttctgc ttttgcttcg attttacttg cgggagtgac
    47881 cgaaccaact gtttacggaa ttgcgatccc attgaaaaaa ccatttgttg ctgcttgcat
    47941 tggtgcagct gctggtggag ctgtaatggg atttgcccaa gtgaaagcga tcgcttttgt
    48001 atttggtagt ctgaccacat tgcctgcatt catttccggt acttttttct ggtacttagc
    48061 aggactggct gttagtctag tcgtagcaat gatcactact ctcgttagcg ggtttgatga
    48121 agacctaatg tcttatgaat agttaatgaa aaagactgaa gtatgagatg tttatcacat
    48181 atttcagtct ttttcttttt aggatcatta tttttataaa tttttgtgat actttccaaa
    48241 ctttggtata atttacatat gcataaccat ttttatcccc acttgtttat ccccaaacaa
    48301 aggtggtcta tgcaataaaa tgaacgtcaa agaaaaacga atgaatgctc gttgcttatt
    48361 tacaaattgt tttatttaga atacacagac agatttatga aaagaaaaag cttttcgaca
    48421 cgattatctg ttccaaaaaa tgtctaatga atgctgaata agacagaaaa tcaatgaaag
    48481 gaaaaggact agtttattat gaaaaataaa aaaacgatac gtttgctagc tgctacttgg
    48541 ctgattgctc cgtctgtttt gtcgaccaat accgtatttg ccgtagataa tcaaatagct
    48601 gatcaaacag tcacaacaga tacgactaca tccagctcag ctactagtga aacaacggat
    48661 tcttttacag aagacccaac tggaacaact aactcaacaa caggatcgac cgagccaact
    48721 gaaattgatc cggctgatcc atcagaaaat gaaaagccag ccgagacata ttcccttaca
    48781 attgctcctt ctttgattgg taagatccaa ctgactgctt cgacagcgga ttcccctgaa
    48841 cagcaacctt tggatattac ggaaagtgga acggtagaag gtttattagc ggaaacgaag
    48901 gtaacttaca ctattacgcc agctgaaggt gaacaaattg cttcagtcgc tgttaatggt
    48961 gccaaagaag taaattatga tgcaaagacc tttacagtag gtacgaacaa tttatctatt
    49021 actgcagaat ttaaagctgg accggatact tcaacagaga aaccaactga tcctagtgaa
    49081 gaagtcccta gtacaccaga tccggaaacg ccaaacaaac cagatgtggg taataacaac
    49141 aataataatg gttcaaataa ttcaaacaat aataacaata attcgaacag cgggaattct
    49201 tcgaatcaaa caaacccatc tggatcgaat aacaatggaa atactcagag agaaccaaac
    49261 catccaaaca atggttcatc gaatggcgga acgaacaatg cttcatctcg tccaaataca
    49321 gcaaatcaaa gcggtataga gaatccatct tctgcttctt ctgattttgt tgtaaaatca
    49381 ccaattgatg ctgtattgcc tacaaataca acgaatgtcc aacaagcaat cgttcgagaa
    49441 gcattcaagc atcttggaaa accatatgta tggggagcaa aaggtccaaa tacttttgac
    49501 tgttctggtt tgacttatta cgtatatatg aaagcaaccg gtcattatat cggtggctgg
    49561 acaggcgaac agcaatatgc aggtacgcag attccagtaa gtcaggccca acctggcgac
    49621 ctcgtcttct ggggaccttc ttccggtgtt actcaccatg taggtatcta tattgggaac
    49681 ggacaattta tccatgcgcc tcaaccagga gataaagttc gagtaacttc tatttcagat
    49741 ttcacgcctg attttgctgt ccgagtaaac ttagcaggtt tacctgctgc ttcaggttcg
    49801 ctgacaggcg gctcatctat tttagatgga ttagatggct cgttccattt cagtcaaaac
    49861 caaacaactg atcagttctt gaaaaagatt gcagatgatg cacaggaaat cgggcaaaaa
    49921 gaaggaatct acgcatcagt catgatggct caagctatcc ttgaaagtgg atctggaaac
    49981 agcttattat caagcgaacc aaatcataac ctttttggta tcaaaggatc atataaagga
    50041 agcagcgtga ccttcaatac acttgaacaa gatagttccg gacaaagcta ccaaatccgc
    50101 gcacaattcc gtaaatatcc ttcttacaag gaaagtttgg aagactatgc cgacttgatc
    50161 aaaaatggac tgactggcaa tcctgatttc tacaaaccaa cttggaagtc ggaaacaaaa
    50221 gactacaaag aagcaaccaa atatttggaa ggacgttatg ctacagatcg ccaatattca
    50281 caaaaattga acgcgatcat cgaagcgtac gacctgacaa aatatgatga accgaaaaaa
    50341 gaagcagcaa caactgaaga agcaaacgct gaaatcctca atatgtctaa gcgattcgat
    50401 gtgccaatca aatggacaac agatggcgtg ccaatcacag gattagaatt ttcaacgata
    50461 aaacgcgtca acaacgcttc ttccatcttc cgtgtcgctt caatctggga tttgtggaac
    50521 aattttacgg caagacagat accagaaaca actactcgta cagttaaagc tgcaactgtt
    50581 cctgtactaa ccttgttaag tttagacaaa tcattctggc ttgatctgcc tttaaagaaa
    50641 tagaataaat taaaaagggg atgtgacact gtcacactcc ctttttaatt tattctattt
    50701 ctttatattt attttgtatt ccgttacaaa ctcgcgtact tggttaggtt ccagagtgac
    50761 atctccaaaa ctttcaagtc gctccgctcc tggcagttct tgagtctcaa atgtgatacc
    50821 gccatgattt actaatttat tcccgcgcat ttccggtcca tcttctccaa aatttgctgt
    50881 aaaaatcacg attcctgaag catctgtttt tacttggatc gatacttttt catctgggct
    50941 tgtcaattcc gcagcattta gtaaaccaga ttgttttttc aacaaaaatg gatgatcgat
    51001 gccgcccact atcattgatt ggcgaaaatc actggcaaag acctcaccta attttttagg
    51061 acgttggaag tcaaatgctg tgccacttac tgaaactact tctcctgtag gcgttgtatc
    51121 tttattgagc gtagcaaata atcggctatt caaccaaagt atatgttcgt cgattgactg
    51181 tgctggatca ccggttaaat tgaaatagac atgatttgta ggattgaata ctgttttgcg
    51241 gtcactgatc ccttggaccg tcactcgcca tgtatcatcg ttcgtcagcg tataccgtac
    51301 ttctacatct aaagttccag gaaatccgtt ttccatatct gggctagtct gatagaaaat
    51361 gaccgatgct tcgttttcac cattgatgac tgtataatgc cactgcttgg cttcaaagct
    51421 aggtgcacca ccatgtaaac aatgaccagt gtccgggtct gtttttactt cgaacgtttc
    51481 atcatctaat ttgaatgtgc cattcgtaat ccgtccagcc atacgtccga ttgaagcacc
    51541 gatataaggg tctttttcta gatattcttt tgcttcatca aaacctaaga tcaactctcg
    51601 tttttcatta tcgattattg tttgaaaatg aacaacccgt gccccaagat cactgacaga
    51661 caaagatgtc ccattttgat tcgtgatcgt aatcaagtga tagttttcgc caaaattttg
    51721 ttcattgatt tccatgttcc ttgcaccctc ttttctttca tttgcactga ttccagcata
    51781 catggaaacc gttttcttaa cagcttattc cgtgagtaac gagaaaaaat ttactatatt
    51841 ctaataaaag accgtgaaaa aaaggttgtg acaaaaatat tgtcacaacc tctttttccg
    51901 aacaaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaaccaaac gaaaaatatg
    51961 aggagctatt tttgcttggc tgttcttatt acttgatgca ggacagcttt ttcacaatct
    52021 ctttttcaat acgattccag tatataacca tgtcgtcagt acatagtaga tgaaatacaa
    52081 tacgaagaat atcgtaaacg gaacccaaat atctttgtat ggattttgca tgaatagacc
    52141 aaacatttgt aatccgaata agacatggac tacacctaag attcctggtg ctaagaataa
    52201 cacgcctact tctctacgga tcgattgttt aagcaacccg cgtcgtgttc ctatcttttc
    52261 aagcatttca taacgagcaa tgtcactctt gcttcctgac aagatcttga acatcaaaca
    52321 gctagcaagc atggtcaaga aagctaaacc taggaagaat cccataaatt caaaaccaga
    52381 gaatagacca ttatacactt catacatttc atatttctgg ttgctgtact ctactttttg
    52441 caaagatgga ttgttcattt tattttgagc aacaagtgtt tcgattggtt tcaggtttgc
    52501 ttggaagtct tttacctgaa ctagctgtaa agtggattgt ggcaagttca gttgatcaaa
    52561 ttctgattga ctgactacct tgatttcttt ttcttgctgt tccggcaatt catagcttcg
    52621 aagttcctct tgtacagtca gttcattcat ttttttagca ggaacttttt ctttcgtgat
    52681 cttcggcggt gttccatctt catgttttat catgatcaat ggttgagccg caaattcact
    52741 tgcattatag taaatcgttc ccgcatcttc tttttgagta taagaagcag aaagtgttgg
    52801 tgaaagttct ttgatttttt gctgatcttc tgcccgagga ttattcatca ctagatcata
    52861 tccagaattg ttttctgtca agtctgcaat ttcattttta aaacctaatc ctaccgtcaa
    52921 agcgcccagt gccaaggcaa acagcatagc gaccattgag agcatttgtg tatattcacg
    52981 aatacgaaag tttaactgtg acaatgtgaa attgttcaat tttttcaatg aaatctgttc
    53041 tgatttcttt agtaatgata aaaagaaaat gatcacagaa tggaaaatga aataagttcc
    53101 taatacgatc gtaactaagg ctacccctat accaaagact tgataggtcc ccacgtgttt
    53161 catcatatag taaccgcagc ctagaaaagc aattcccagt actacttcaa ggaaaaacaa
    53221 gaatttatgc tgcttgattc ttgttggtgt ctgatccgca cgaatcaatg ctaaaatcgg
    53281 ttttttgaca atcgaaaaag cattgacaac agcagctaat aaaaacaaaa cagcaaaaaa
    53341 caaaacagtg atcaacaacc cgtgaatact aaaaggtgta aaatgcgaaa tattgagatc
    53401 taactgatcc actaataatc ggtggacgat acttgtcaat cctacaccga cagctgaacc
    53461 cactaaagta gctgcgatcc ctactaagaa tgtttcagaa aaaatcatct gtgcgatttt
    53521 tctgcctttt gctcccagca tcataaacat tgcatagtct ttttgccgca tcgtcatcaa
    53581 aaaggaattt gcatataaaa tataaacgaa tgtgatgatc cctagtaaaa cagaaccgaa
    53641 tcggaaaatg ataactgtag ccgcaacgat cgtattactt ttcaaaaaag cttcgttgct
    53701 tgccattgat tcaaacatgt aaaaaatagc agatgccata actaatcctg agaataacac
    53761 caagtagtct cttaaacggc tcttgatccc agtaagtgat aatttccaaa gcatagtcaa
    53821 tctcccccta ctgttccaag tttccaagaa tagatagtat ttctcgatag aaggaatcac
    53881 ggctttgatc tccacgtttc acttcttgat ggataccgcc atccttgatg aataaaatac
    53941 gttggcaata acttgcagaa aacggatcat gcgtcacaag aagaatcgat acatgatctt
    54001 ttgtattcaa ttcgtccatc gtatctaaaa gatcccgggc acttttggaa tccagcgcac
    54061 ctgtaggctc atcccctaat agaatcgttg gttgtgtgat caatgcacgt gcggcggcga
    54121 cccgttgttt ttgtccaccg gaaatctcag aaggatagct ttccaaaata tgagagatgg
    54181 ataaacgttc tgcaattttt tggacacgtt gcttgatttc ttttggtctg acgccttgta
    54241 aagaaagagg aacagcgata ttttcttgtg ctgtcaagct ttctaataaa ttgaaatctt
    54301 ggaaaataaa gccaatctca ttcgcacgaa aatctgctag ttgatttcct tttaatgtgg
    54361 tcacatcttt ttgattgatt cggatatgcc catctgttgg tttatctaat gtggataaaa
    54421 tattcaaaag tgtcgactta ccagaaccag aagcgcccat gatcccaata aattcgcctt
    54481 tttctacatc gaagctgatg ccgcttaatg cttgcgtctt tttctcattg ttttttccgt
    54541 atacttttgt tacattctgt acttcgacta ttttgttcat ttctttccct accctttaat
    54601 tagtttttcc agtgctgttt tcggcacgtc ttttttttcg acttcttcat acgaagtgac
    54661 acctttattt ttgttccagg tgatttttaa atatgctcct ttacgaagcg gtcgagtcaa
    54721 ttgtcccttg aagtccagtt ctttttcctt accctctttc gtatagccag gcaggatata
    54781 tctatagttg actgtttctt gtccagagtc tgattttgaa actgtttttg taccatctgt
    54841 cgtaatttgt acatagtatt cttctccacc cataactacg taatctgcga ttttcacccc
    54901 tgcaagtacc acaacgatga aaacaagtag accgatcaga agttttttca ctttttcccc
    54961 ttctctctta ctttatatac tgattataga aaaaagcgaa caattctgcc ttcgaatcaa
    55021 ctatcattct tctttcaatt ttgtcatttt ctttaaaaca actaaaaaaa gagttcaaga
    55081 caataatccg tcctaaactc cttcttccta tcttacaaaa agtatgtcac ttacggtctt
    55141 tcatgtcgcc tgtattgata acaggttgcg ttcctttgtc tgtaatgatt gagacaagta
    55201 aattattgat caattggact ttccgatcat cggtgaaatt gatttcttgt ccatcttcga
    55261 tttgctctaa ggccatttga gtgattgtga cagctccttc aacaatggtt tgtcgagcag
    55321 acaaaatggc ttttgcttgt tgacgttgga gcatggcact agcgatttct gttgcatagg
    55381 ctaaatggtt caagcgtgtt tcgattactt cgacacctgc tactgctaaa cgctcttgca
    55441 gctctttttg caactcgtca gacactgccg tcgtgtttcc tcgaagcgtc aaatcattct
    55501 cattgaatgt atcatacggg tattggctag cgatatgccg aatggctgtc tcactttgga
    55561 tttctacaaa atcttgataa tacgctacat cgaataatgc ctttgctgta tcaacgactt
    55621 taaagactac tactgctgag atttcgatgg ggtttccatc caaatcattg acttttaaaa
    55681 cagaactatt gaaattccga actttcaacg aaacagtcat tttttgtgcc aaaggtatcg
    55741 taaggaaaaa gccattttct cgaatcgtgc ctaaatattg tccaaaaaac aaaattactt
    55801 ttgcttgatt aggactgact acagttgccg aacttaacaa caataacgtg atcaaccaaa
    55861 gaaaaatact taaaaaaagt gcccaaactt tcgcttgcca catacctaaa tagaagaaaa
    55921 acaatccaac taaagctaat acgaccaatc cgacaatccc tgcataacca ttgatataaa
    55981 atgctctttt ttctctcatg ctacttcctg cgctccttta tccttcaata aatatctaat
    56041 gttacttttt taattttttt ttcgaatacg cgccattaca ccttctagtt ctaactcttt
    56101 gtcttcagtg atgtaccaac cgcttgcctg tgtccctccg gctgcctgcg gtaaataatc
    56161 caattttgtt cgaacccagt gcttttcttc tgtaaaatag tcttctacca agacctctag
    56221 atccatccct gctgaaagag gcaaatcttc ccgaacagat ttaaagataa atcgttcctt
    56281 cttcccatca tacttcaata ttcctgtatc gataatcggt aaagaataat aatccagctc
    56341 tttcttcacc gtcaataaat gtttgaaaac ttcatggtac acttgctcta attggcgacc
    56401 ttctgaattg ttcgggtaat taaccatcac tttttctttg tctggatcat agaaggtttg
    56461 gcttagttga gtgatataag tatgtaatct ttccatttct gtttttaact tttctctttg
    56521 accttcttct accttcatat actctttcac cctgttttct ttttagatat tttctttctt
    56581 attttactat agttatgtgc gttaagcgat gaaaaacagc aaagattgga aggatctttg
    56641 ctgttttttc ttaaaatatc cagttgagta caggatcaat ctgtttcatt gtcctcttga
    56701 tccgtcgtaa tattgatcga tgtgtcttta gcagtgatct ttagcttttt ctgtccttgt
    56761 tctaacaaag tatttgttat tggctggtag tctttttcaa tataagattc accagacgtt
    56821 tggatagtat agccactgtt ttccatctca tgcaaagata aattgccacc gtttaggatg
    56881 acttttcctt ctttgctgat caaactgtct tctagatgga agttgctgtt ttcacctgtg
    56941 acgatcaagt tatccacatt ggcctcatct aatcgaagtg agcctaattc atctttcgca
    57001 gttattgttc ctcctgtaaa ttcattgaac gatacccagc catcatgtgt cttagtattc
    57061 acttttttga ttgatacttc gttgatatca attgcactat tattcccttc gattgtcaat
    57121 tcagataatt catgatctgc agggacaaca atagtgattt gtgcacttgt gtcttctaaa
    57181 ctaatgattg cacctgttga ttttttgact gcattcacag tcaacacgcc atttttctcc
    57241 tttatttctg gcttttctgt cttatcataa gtcgttttta tctcaaaatc caatccgcgt
    57301 atgaccgaaa ctgtttgatt ttctgcatgg atgacgattt tgtttgcatc cttgattttt
    57361 tttgtctcag taaccatatc gatcaaccga ggaccattat cccaagtcag actcttttga
    57421 gcgcctaatg tataagttgc acctgctagg aggccaccag taagcatcag accaataccg
    57481 gtaatcaaaa aatgtttcaa tctcaattta tgtgtcctcc ttcaaacgcc cgctgaatgc
    57541 agatctcttt ttgtaataaa acgtcgtccc atccatttaa caaagttcat catgacataa
    57601 aaaagccctt ttgttccttt cagcaacagt ggcgaaataa atactgcgct tcctgtggcg
    57661 aacagaccga caccgataaa gaataatcca ctcagaatcg attgtccaaa cacactgatt
    57721 cctgagatga tcatgaatag gccaacacct aagatactga tacataaaac atagatacta
    57781 aaaatgagcg ctagtaaagc aaccaatagt cccccaataa ccaatataaa ccccagtgct
    57841 agtggaatga ggacaggaga agcaaataaa ccgataatga ttaaccaaac caggcgaatt
    57901 tgtctttttg gatttttcac taactcgttt tctgcttgtt cttcttctga aaagtaactg
    57961 atttttaatt ttaaggcaaa ctgctttggt gtaccatatt catcaatgat ctgatctaat
    58021 gtttttccag aatctaaaaa atattcctca taatactgga tcaaatcaaa acgatcgtct
    58081 tcaggaattt cttgaagatg atccacaact tcattcaaat attcattcat ttgtgctctc
    58141 ctccaataac cggtctaaag aatctcgaaa aacaatccat tcatcaataa tttcttctaa
    58201 atgacgactt cccattggtg tcaacgagta atatcgacgg tttctgcctt caaaaggttc
    58261 atcataggtc tcaagatatc cttctttttt caatcttctc aaaaccggat atagtgtaga
    58321 ttcactgaca gagagacttt cttgtacgat ttttgttaag gcatacccat acatatcttc
    58381 cttgcttaat gctgctagca cagtaccatc aagaagaaca gttggaatct ggatgtgcat
    58441 tacgtcacct tctattctca agtgtaatat tttatttcaa tctatattat acaacatata
    58501 atatagtttc aaaatcagtt tgtcaaatac aaaaaaactg actaaaagat ttgatccttt
    58561 ttagtcagca aaaaatggct tctctttgat ttttattata acagtggcat aatccaattt
    58621 gtccacatcc agctcagtgg catgataacg atcattgcag gtatcatgtc agctactggg
    58681 aacattttca cgttgatcat tctaaaaccg gtagcgacca tcaagaatcc gccgcaagct
    58741 ttaaaatcta agatcatgtc tggtgtagtc aatggataaa taaattttgc caataagaac
    58801 aaaatataaa aaataatgaa ttggggaatt gctatcacag aaacgacata ccctaaatta
    58861 cacgcaaaaa tagctgctgt gaaaaaatca aggacagatt tagaaatcaa aatcgtactg
    58921 tctcctgtca tcccagaatc taaacttcca tagatccccg taccacttgc acaaaataga
    58981 acaatgaccg tcactaatgt gctgataaat tcatcgtggg tcataccaag cttttcacta
    59041 gggaagattt tagaaatagg tacttgcatc agcgcagccc ccttatttat cccattacct
    59101 aaatgaacaa tcaaaccaat cgctgttcct atcactaaag caaaaataac agccggcata
    59161 tttttcatcg gcgcaatgga atagattccc atccccatcg aacacacacc aaaaaccatc
    59221 gtcagctgtg ctttaaaatg ttcacttaat ttatttccta ctaatccgcc aattagtccg
    59281 ccaaacaaaa cggaacctac attgatcaaa actccagttg gcatcaaaaa actcctctct
    59341 ttttctacga agcgaaaaaa atcagaaaaa tttctgtaat tattgctttc gctgcaagaa
    59401 agattgtaac agacagagaa gattacacca attcattttt tgtgttaaag tattctttat
    59461 tggaataagt aggaggaata tgatggatat ccataaattc gaagtttttc ttgatttagc
    59521 cgaaacaatg aatttcacca aaactgctga tcgacaattc accacccaag gaaatatttc
    59581 taaacagatt ctttcgttag aaacagaatt agacgtcaaa ttattcgaac gcgcccatag
    59641 aaaaatcgaa ttgaccgaag ctggaagctt attgctccca tatgtaaaaa atgtcgtaga
    59701 acaataccat gctatgcaag aagtgcttga aacctatacg aaagacaaca atctttcatt
    59761 aaatatctta acgataccga caatgatcaa ttataaaggt ttttccaaaa tcaccgagtt
    59821 tttgaaacgc catcctgaat ttacagtcca gttgaaagaa gtggaaagtg tcgaattaac
    59881 ttacaatgac gccaatgaac atagtgacac gatccacttt gctagaagtt tccaggcccc
    59941 accaagttcg attgagtggt tgcctactga aacagacgat tttgtagcag ttctacctaa
    60001 aaatcatcct ttagctagta aaaagaaatt ggatctaagc gaactgaaaa aggagaactt
    60061 tttgctcctt ggccccacta cgaacttgta tcaacctgta ctagatctgt gtcgcgaagc
    60121 tggatttgaa ccaaaaatct cttataaagg agcaagaatc gacttgatca tcaatatgat
    60181 tgcaaatgac atggggattg ctattgttat ggaaaaaaca gtcaagaatc tattaaaaga
    60241 aaatactgtg attctcccta tttctccaac aacagagagt tatcttgcat ttactcgtaa
    60301 agtcggtgag cattctttgg cttcagatac attttgggag tatttaaatc aagaagaaaa
    60361 ctaagcccta cattttctgt ccatctatcc acccaaaaaa agagagcgac gcatgacttt
    60421 cgctctcttt cttgcatcat gtccttgttt caatgacacc tctaacattt ctcgtagttc
    60481 aataagaaag cagcgatttt tatgccaaaa gaaccgtaag aacatttccc taatcacaaa
    60541 aaaacgacta aaaaccccta aaaaccttca atagaatttt taggggtttt attctttttc
    60601 ctattgttta cttaaccgta tcattgctgt cgttcctact ccttcgatac tgctataatc
    60661 aatacgtcca tcatgcagtt ctagaatttt tttaaccagt gaaagtccta gcccattccc
    60721 agaaatttga cgacttgtat ctccttgata aaatttttca aacattcgat ctctggtctc
    60781 ttcattcatt cctacacctg aatcggtcac ttccagtaca atctctgtgg ctgtctcaaa
    60841 tagtttgata tgaatctgtc cattgatttg attgtacttt atggcgttat ccatgatatt
    60901 cagccacact tggtacaaaa actcttcatt gcctgtgtaa tttactgcag caagttcgat
    60961 atccaattct agctgttctt tctcccattt aggctgaaaa aaaacgatta cttctctgat
    61021 ttgttcatct aatcgatact ctttcttttc cagttggata cgctggtttt ccagtttgtt
    61081 caattttaag atgttctctg ttaattgtga aagctgcgtg atactttcga taatccgata
    61141 taaaaatatt tggcgttctt cgtcagagag atttggggct tgtaacaatt gaacatatcc
    61201 ttggattgtt gctagtggtg ttttgaattc atgggataca ctggacacaa agtcattcct
    61261 cagtgtctcg atactattga gttcttggac cataacgttg aaatctttat acagttgctg
    61321 tacttctgct actttctgct gttcatccat tcgaatcgaa aaatctcccg ttgctaccag
    61381 actcatattt gtccctagcg cactgattgg atgcaggata cgccgcccaa caaaaatcga
    61441 tattcctgta cccacgacca tactgaaccc cgcaaagacg aataacgggt ataacgttgg
    61501 ttttccagcc gattcagcag gcgagataga atgtcgagac aataagaaaa taaaaccgag
    61561 aaaacacagc agtgtcacta agatcgaaat gaagacaata ctagcaaaat agatccataa
    61621 ttgtgaaaat agcttttttt tcatctttaa ataaccgcct tatagcctag tccccgtact
    61681 gtgatgattt gaaaatcttc cgtcttttca aaacgggtcc ttaaacgttt gatatgtaca
    61741 tcgatcgttc gttcttctgt attcgtatct aatccccaaa tatcatccat caactgttgg
    61801 cgagtgaaga tcttgttggg ataagacagt aatttataca gaagcagaaa ttctttttga
    61861 ggcagaatca acgaatgctg atcttgtaac actgtataag catctagctc taattttgtt
    61921 tgtccgatta tcaagctact gctgtaattg atctttgaac gtcgaagcaa tgcttccaca
    61981 cgtaggatca tctcattgac atcgatgggt tttgtcatat aatcatctgc tcctaatttg
    62041 aacccgcgtt tcttatcctc aaaatcggcc tttgccgtaa tcattagaac aggtgtgtca
    62101 aatctggtgc tacgtaatga gtctagcaag tcatagccat ccattttcgg catcatgata
    62161 tctgtaatga ttaattctat acgtgtcgct tctagttttt tcagcgcatc ctctccattc
    62221 aatgcggtga tgactgaaaa gcccgctcgt tccaacacag aacggtaaag caactgtaat
    62281 tgcggatcat cttctactac taaaatacga ttcattgatc tccctctgtt ttttgaaaaa
    62341 tttctagatt ttttcttgta gttcatcttc agttaacatt tatttcgtat actacgatca
    62401 ttgttctgat atacttatta gtataccgaa tatttcaata cgggagaagg gtgattatgc
    62461 ttcaattaaa agatataaaa aaatattata aagtcggcga aaccaccacc aaagcattgg
    62521 atggtgtgtc tgtcgctttc agacaaaaag aattcgtagc gattttaggt cctagtggtt
    62581 ctggtaaaac gactatgctg aatgtgattg gtggactaga taattatgat tccggtgata
    62641 tggtaatcaa cggaaagtct actaaagact ttaaggacag tgactgggat gcctaccgaa
    62701 acaactctat cggtttcatt tttcaaagtt acaacttgat tggtcatcta ggcattattg
    62761 aaaacgttga acttgggatg acattaagtg gtgtttctaa agacgaaaaa cgaaaacggg
    62821 cagaagatgc attgcaccga gtcggcttga caaatcatat gcataaaaag ccaaatcagt
    62881 tatctggtgg acaaatgcag cgagtggcca tcgctcgagc actagccaat gacccagata
    62941 tccttttgtg cgatgaacca accggagcgt tagatacaga aacaagtatc cagatcatgg
    63001 aattgatcca agagttatcg aaagaaaaat tagtgatcat ggtcacacat aatcctgaac
    63061 tggcccatca atacgcagat cgaatcattg aattttctga tggtaagatc ttaacagatt
    63121 cccatcctca catcgaacga ccaaaagatg atcaatttaa cttacgcaga acaaagatga
    63181 gtttttggac agcgttaaag ctttccttca acaatatccg aacaaaaaaa ggacgtactt
    63241 tcttgacctc ctttgcttcc agtattggga tcatcggaat cgcgatcgtt ctgtcccttt
    63301 cttctggatt ccaaaaacaa atcgataaca cgcaagctga aacgatggcg aaatttccga
    63361 ttactatttc taaggtaacg actaaccaga ctcgtgacga tgccggattg ggtgcaagca
    63421 aagcggatta tccagacagc aaaacgatta ctgcaaaagt cagcgaagaa gataaagcac
    63481 agcacacgaa taagattgat caaacatacg tcgattacgt aacagacatc gatcctaact
    63541 taagtaataa tatcggattt acccgtacta caggaatcaa tcttttacgt gatgtaaatg
    63601 gcaaagtaca gcctgtcagc ttctcgaatc aaaatcctga tacggaatct ctttctttat
    63661 ctagtacgat gtcagcaatg acaggtgtgg gagtgtcaag tttccctaca cagcttgaca
    63721 ctagcaaaga aaacttttta aaagacaatt attctttact tgccggaagt tatccagcct
    63781 cagcaacaga tgtcgtgctg atcgtagacg gcaataataa tactaatatc aacgcattga
    63841 agaatcttgg atttgatgtg aaagaagacg aaaaacttga ttttgatgat atcgttggta
    63901 caacattcaa attagtaaac aacaatactt actatacaaa acttccaact gggaatttta
    63961 tccctaatac agattatgat gcgatgtatc agaatgcttc tgatgaattg aagatctcgg
    64021 ggatcctacg cgtgaaatct tcttctacaa tgaatctctt atctccagga atcgcttata
    64081 gcgatcaatt aacgactcaa atcgtcaacg aaaacaaaga atcagaaatc gtcaaagctc
    64141 aaagagacag tggtgtaaat gtcttaacta ctgaaaaagt tgacgaaaat gccaaacaaa
    64201 cattgcttag ttatttaggt ggagacagct tgccttcaag tatcatgatt tatccgaaca
    64261 attttgaaga caaagaaaag atcttggatt atctagatga ttacaataaa ggcaaatcag
    64321 atgaagataa aatcatttat actgatttag ctggaacgat gactgaactg actggcggat
    64381 tgatggatgc tatcacttat gtccttattg cttttgcagg gatctcttta gtaacaagta
    64441 tgatcatgat cagtatcatt acttatacat ctgtgattga acggacaaaa gaaatcggtg
    64501 tactaaaagc tttaggtgca cgtaaaaaag acatcactcg cgtatttgac gcagaaacgt
    64561 gtattttagg tatttcttct gggatattag gtgtgtttat tgcatggcta gctacgttcc
    64621 ctatcaatag catcttatac aacatgacgg atctaaaaaa tgttgctcaa ctaaatcctg
    64681 tccatgcgat tattctagtg atcgtctcta ctatattgac gatgcttggc ggtcatcttc
    64741 ctgcacgaat ggcagcgaaa aaagacgccg ctatcgcttt gcgtgcagaa taaggttgtg
    64801 acaaccacat ttagatttga gtcataagag cgctgaaata gtagaaaaca gcaagaaacg
    64861 aggaagtaat atgttccttg tttcgcgctg ttttttttaa ttatttttta taattctggt
    64921 atacttttct ttcctttgta ccacaactct tctggcgtat acctgtcttt tccatttatg
    64981 aatactgttc catctgcttc aatcgttact tcagtcccaa tccacatatt acgagaaagt
    65041 gcgagaagat tttttctttt tcctcttcct ttttttccaa attgcaaggc atcggttatc
    65101 tcttctgtcc aatgagattt cacgtatttt acttctccgt tttcaaatgt aactttcaaa
    65161 atattcgcta tattttccac ttttactgct ttaggaaatg actcctccat ttttttcact
    65221 ttccttcctc caacactaag tatgcgcttt cttttagtga taagtatatc atagtttatt
    65281 ctattatcaa aaaaacgcat ccattccatt gtagaatact ttaccgaaca agttgaattg
    65341 ttttcctctt tttcaccttt tactatagat aggtaaagac aactaaggag gaatctctca
    65401 tgacagatca accgtatgat ttaagaaaag tcatcgaaga actaaaaaca cttccaggtc
    65461 aatatcacga aacagatatt gaaatcgatc ctgaagcaga attatctggt gtttaccgtt
    65521 atatcggtgc tggcggtaca gtaaaacgtc cgactcaaga aggaccaact atgactttca
    65581 acaatatcaa aggtttcccc ggcacacgtg tgaacatcgg aacaatggct agtcgtaaac
    65641 gtgtaggtga aattttgcac catgattatc gaacacttgg tcgtttcttg aaagacgctg
    65701 tagaaaatcc aatcaaacct gtgaaagtag acaaagcaga cgctccagca caagaagtcg
    65761 ttcatctagc taccgatgca gacttcgata ttcgcaacat tttgcctgca cctacaaata
    65821 ctcctgaaga tgctggtcca tacatcacaa tgggtgtagt cttaggatca gatccagaaa
    65881 aaacaatgag cgatgtaacg atccatcgta tggttctaga agataaagat acgatcggta
    65941 tgtacatcat gcctggcgga cgccacattg gtcacttcca aaaacaattc gaagccttga
    66001 ataaaccaat gcctatcact atcaatattg gtttagatcc agcaattgcc attggcacga
    66061 ctttcgaacc acctaccact ccacttggct acaatgaact atggtgtgca ggagctttgc
    66121 gtaacgaacc tattcaaatc gttgatggta tagcagtcga tgaagtgggt attgctcgtg
    66181 ctgaattcat cattgaagca gaaatcatgc caaatgaaac aatgcaagaa gatatcaaca
    66241 cgaactcagg aaaagcaatg ccagaatttc ctggctatac tggggatgct aatccagctg
    66301 tacaagtagt gaaagtcaaa gcagttactc accgaaaaga caatccaatc atgcaaacaa
    66361 cgattggtcc cagtgaagaa cacgtatcta tggccggtat tcctacagaa gcaagtattc
    66421 ttgccttggt cgataaagct attccaggaa aagtagtaaa tgtctacaat cctcctgcag
    66481 gtggtggtaa attgatgacc atcatgcaaa tccgtaaaga aaacgaagcg gatgaaggta
    66541 ttcagcgtca agcagctatt cttgctttat cagccttcaa agaattgaag acagtcattt
    66601 tagtcgatga agatgttgat attttcgaca tgaacgatgt agtttggact ttcaacactc
    66661 gtttccaagg agataaagat atcatcgtga tcccaggaat gaggaaccat ccattggacc
    66721 catcagaatt accagaatat aatcctggct ctattcgttt ccgtgggata agtgcaaaaa
    66781 ctatctttga cggtacagtt cctttcgata tgaaagaaca ttttgtacgt gcaaaattcc
    66841 aagaagtaga agattgggaa aaatatttga aataatgaat gatctgcaac tgttttgaca
    66901 tcataaaaag gagtgcggaa aatggaacaa ttggcacaac ggaagaaaaa aatcgtgatt
    66961 ggtgtaagtg gcgcttcagg caccatttat gccatcaacc tagtgaagaa actaaaagaa
    67021 tatccgatga tagaaacaca cggaatcatc agtccatggg caaaacagaa cttaaagctg
    67081 gaatccgact tatcactaac tgaattcgaa agcctgtttg attaccatta ttcaaacaaa
    67141 gatttaggtg ctgctgtcgc cagcggatca tttttgaccg atggaatgat catcgtaccg
    67201 gcaagcatga aaacagtcgc aggtatctct gttggtttag gcgacaacct gattgcacgt
    67261 gctgctgatg taacaatgaa ggagcaacga aagttagtca ttgttcctcg tgaaacgcca
    67321 ttaaatgcca ttcacttgga aaacttgact aaattagcac gactaggtgt gcaaatcata
    67381 ccaccaattc ctgcttttta taatcagcct caaacgatcc aagatcttgt taatcaccat
    67441 acaatgaaac ttttggatca atttgaaatt gtaaatgagc attcaaaacg ttggcagggt
    67501 gattaatatg gaaaaagaaa cgatagttga agtaaccaaa ctaggtttca cgatccaagc
    67561 tgctgttaaa gtaatcggta aagacttatt gatcacttta acaggcggag atacaccaca
    67621 tatcggaaca gtcactacat tttctcgtga tacagagatg caaactgtac gtttccctag
    67681 ccacgatggt cggttccata aagacgatgt cttagccgaa aaaatagctg tgatcatcaa
    67741 aactgccgtt ccgggaagtt gtacgatcac ttccggtatc catgttgacc atatctccaa
    67801 tgcacaaatc aacgcctctt ttccgatgtc agaagagtta ggttacaaga ttttagattg
    67861 gttggaaaaa atagatttcc atatcaaaga accagtttat tataaagatg gtgaaaaacc
    67921 attatgaaag aagaggttgt gaaatcagcg ttatgacctg agtatgagag aaaaaaatgg
    67981 aaaaatagct tctcatattt tgccgttttt gagctaatac cgagggacag ctgattgaac
    68041 gccgtttatc aagaggttgt gataaagccg cttcgtttcg agtagtaaga aaaattttgt
    68101 aaacatgggt ttccacattt ttgcataaat ttgacttact accgagaaac tggcttttga
    68161 acaccgttta tcaagaggtt gtgacacgtc ttttgtcaca acctctttta tttttgcttc
    68221 actgtaactg ctacaatatc accgatttct tttccgatgt ttttacgaat atcttttcgt
    68281 agtccaagga tgtagcagac tgaaccatct ggatttttca cgcccatatt cacgatactg
    68341 ccttcatatg gcacattgtc aaaagttgct tggactttaa ctcttccagc accgaattct
    68401 tttcttatat catacggaaa aataatatat gccccgccct tgccgacttc ggaagcatag
    68461 atttttgatt caaaagaata aatttccctc attttatttc tcctattttt tacatctagt
    68521 atagcatagc aaaaaaaaga aggaactgtg acaaaagtct tgtcgcagtt ccttttttcg
    68581 aataaacggt gttctcctgc caactcctcg gtcacaagtc acaatagtca acaaacatga
    68641 gaagctgttt tttgaaattg ctccttgtga ctcagagtta aacggcaggc tcacaacctc
    68701 ttccttaaac ggtgttcaaa agcttgcatc tacggcacta agcccaatca gatgaaaaat
    68761 atggagtgct atttttatct gattgttctt actgcttgat gcagagcagc tttttcacaa
    68821 cctcctacat ggtgttcaaa atattattcg ccttttgctt ctttcactaa ttttgcgaat
    68881 gcttgttgtt ggaattcagc agctaaggct ttcgtacgtt gttcttgctc tgctttgctc
    68941 atttttggat tttcagtcat tgcttttacc ataccgtctt gaacataagc ttttgcttca
    69001 ctttccatcg tactttgctg tttcttcact aattcagcta acttggctgc ttggtccgta
    69061 cttaattcta cccatgtctc tgggattttg aatgtattca ctcggctgtc atattcgtga
    69121 ttgttatcag caatattgaa ccagaattta tacatgtcgt ttttgtattc ccaataagta
    69181 gttttcgtca ctttttcagc atcgccgtct gtcttttcta ctttatttgt ttcgttatcc
    69241 gtaccagttg cttttggttt ttcttgtttt tcatttgttc ggtaaagata cactttttct
    69301 tttccattcc ctaaagcttt atacaaaagc atatctgctc cttgggaatc agcactggaa
    69361 acaatttttt ctgtttttgt ttccgttact ttttccattc caaagtgatt ggacaaatta
    69421 gcgacgatca aacttagtga agcgacgaag attagtccga aaatcaaaga taaaaaggtt
    69481 tgccatgttt ttttagcgaa cacgttcgtt aaagcaaaag caagcaagct gacaatcaaa
    69541 actccaataa tcatgcatta tcccccgctt tcattagaac aggttctttt ttcttcaata
    69601 aaaaggcaat aataaagcca agaatcccaa agatgatcgc tacgataaac gcggcatggt
    69661 aacctgacag tgtggcattg attgcctgat ctttataagc taatggcgta ttatccaata
    69721 cagatttgct tgggatattt gcttttgtca cattcgtcaa cacactgatc aaaatagctg
    69781 taccaatcga gcttgcgatt tgacggaatg tattatttac cgctgtccca tgactgatca
    69841 agttatttgg caatgcattc ataccagaag tcgttaccgg catcatgacc atggagatcc
    69901 caaacatacg gatcgcataa aggatcacga tatataaaac tggagtcgtt tttgtcaaga
    69961 aagcaaatgg tgcagttgcc gctgtcaaaa tgaacatccc tgtgatggct aaacgtttcg
    70021 cgccgtattt atcgaaaatc gcacccgtca caggcatcat agcccccatg atcaatgcac
    70081 ccggcaacaa catcaagcca gaatggaatg ctgattctcc acgaatattt tgaatataca
    70141 atggtacgac catttctgcc cctaccatcg ccatatttgt tacaccagct aaaacagctg
    70201 caatcgtgaa tgtagatgat ttgaatacac gaagttccaa gaatggatgt tccaaatgta
    70261 attgacgcca tgagaacaag gcgatgaaaa tcacaccaac aactaagaaa ccaattactt
    70321 tcaagcttcc ccagccgtca tctcctacac tagaaaatcc gtaaagtaaa ctaccgaatc
    70381 caatcgttga taaaatagcg gataaaatat caatgctagg atttgacaat ggaataacac
    70441 ttttcattag gaagaatgct aaaaccaaga caagaacaac gattggcagt accataccaa
    70501 acaagtcacg ccaatggtag ttatcaatga tataaccaga taatgtaggg cctaaagcag
    70561 gagcaagtcc aataacgatc cctgacatcc ccattgctga tcctcttttt tctggcggga
    70621 aaatagatag catgatattt tgcaataatg gcatcgatac tcccacaccg caagcttgga
    70681 tcaaacgacc gattagtaat gtactaaaat taggtgctgt aaagcaagta atcgttccga
    70741 tcaaaaagat cgtcatggca gaaagatata aatttcttga actgaattta ttgatcagcc
    70801 atgctgttat tgggatcatg atcccgttga ctagcaagaa accagtcgtt aaccattgca
    70861 catcagacgc tgaaatatcg aaagctttca tcaatgtagg aaaagctgtc gtcaataagg
    70921 tctgattcaa aacggtacaa aatgtaccaa ttaataagac aacaactaaa agtgtccgat
    70981 tatatggttt tccgtaaata tctacgggtt ggttgttact catatttctc cttctttctg
    71041 aattttttct gaaactacta gaatacttta gtcctaaatt cgctatttgt caacctactt
    71101 gacacataag ttaatacgga tataattaag ggaagcaaga ggacaaaagg agtgacaaaa
    71161 atggttgggg cttcccttaa acgtttgttg gaaaatgatc aattggttgt tggcatcagt
    71221 gaattaagtg atatcgtagg tgtgtctcca cgtcaattaa ggtattggga acaaaaggga
    71281 ttcattcgtt cgatcgaagc tgatgcgaat tgtcctagaa aatatcgttt acctacagtc
    71341 ataaaagtag aactgatcaa aaaatattta gatgacggat ttactttgtc aaaagctgca
    71401 gaaaaggcag aaatccgcca aaagaaaatg caccatgtcc gtaaagtttt ttcaaaagca
    71461 atcaaagata tcgaattgat cgacgaacgc tatacgattt tacaaatcgg taacttcaaa
    71521 gaagagaatg ctaagatgta catcattcat gacaacgaga cagacgaatt aacttacaag
    71581 ctccttcctg tcgatgaaaa agctgactac gaacagttgt taaaagaact ctaaacgcca
    71641 ctaatctcct aagtaccaag ctttttaata agtagatgct acataaatac ttgaaaaaag
    71701 gcctgtttga acataagaat atccgaacgg tgatctgcgt ttctttcata tagaaaggaa
    71761 ttctccatca ctgttcggat atttttttat ttttttcggt tactttcttc taatacatct
    71821 gttagccaat ttgcatattc tgtttcccga ttgatcgcat gcgctaaaat caggtagtgt
    71881 ccgtaatttt catgtttttc tttttcagta ggaaagatcg ttttttttcg ctctaataga
    71941 tgaagtcgtt tttcttcatg aaggtcacgc tgctgctgaa taatttctac taatgccgga
    72001 tcattcacgt ctttgacgaa atacaatttc agaacaaatt cgtctcgatt aaccggtagt
    72061 tcattggtgg gtgtatgaat ccactctgcc aattgttcct tcccttcttc tgttaattca
    72121 taaactttct tttccaattt ttcacctgtg atctctactt gatgctgaat gattccttgc
    72181 tcttccattt ttgcaagttc aggataaatc tgactatgtt ttgcttgcca aaattctcct
    72241 atttcatttt tgaacgattg attcaattca tatcctgtca tcttcttctt acttaataac
    72301 cctaacaaaa tatatcgaag tgtatttttt cttgccatca gttttccctc cttgacaaat
    72361 ctttaaatcc attctatcat aaatgagtaa tcgaaaacat gtagtttatt acatgtttta
    72421 atttataagg agatgcttaa acatgaaaga atttaaagaa ttggaagatt ttattggaac
    72481 tcactttatc tatacgtatg acaatggttg ggaatatgaa tggtatgcca aaaatgacca
    72541 tactgttgat taccgtatcc atggcggaat ggtcaaaggc cgttgggtaa aagaccaaga
    72601 agctgatatc gttaaattga cggacggcgt attcaaaatc acttggacag agccaacagg
    72661 gacagacgtg gcattggact ttatgccaaa tgaaaagaaa cttcacggaa tgatcttttt
    72721 ccctaaatgg gttgaagaac atccagaaat cactgttact ttccaaaacg aacatatcgc
    72781 agaaatggaa gcagctcgtg aaaaatatga aacttatcca aaattacttg ttcctgaatt
    72841 tgctacgatc acttatatgg gtgatgcagg tatagacaat gaagatgtta ttagcgaaga
    72901 accatacgat ggaatgccag atgatatccg tagcggaaaa tacttcgatg aaaattataa
    72961 acgagtaaaa taaggttgtg aaagagaggt tgtgaaatca gcgttctgac ctgagtatta
    73021 gagaaagaaa cggaaaaata gttcctcatg ttttgccgtt ttttgagcta ataccgaggg
    73081 tcagctgatt gaacaccgtt tatcaagagg ttgtgaaatc agcgttatgc tttgagtaat
    73141 aagaacgcta gttagaaaat agcttttcat attttctagg ctagtgggct tattaccgag
    73201 aagcagccgt ttgaacaccg tttatcaaga ggttgtgaaa tcagcgtttt gacctgagta
    73261 ttagagaaac aaatggaaaa atagttcctc atattttgcc gttttttgag ctaataccga
    73321 gggtcagctg attgaacacc gtttatcaaa gattgtaaca actgcatatt cacacagtta
    73381 aattagtgac ttcaaaatga aataatgctc ccagcaaaaa attaggctgg gagcattatt
    73441 tcgttattct gttcatcaaa aatcagcgtt ttgattccat ttcatcacaa gttcctcctc
    73501 atttactgct tcatcttttt gctgtgtttg aattgtaaaa ccttgtgaaa gatagaaatg
    73561 aatagctgat tgattttttt gatagactgt caaagtcagt gttttattgg tttcttttat
    73621 ttttttcatt agttgcgtac cgattctttg ttgccggtat tcccttttca caaagattcc
    73681 tgcgataaac tgatcaatca ccccagcaaa accaataatt tcttgatcta tttctgctaa
    73741 gtaaatcact gcatctggta aagctttcct aacagattct acttgattct cccaataagt
    73801 tgatggaatg aattcatgag aatccaagtt agcatgcagc caaatcgata gaacagattc
    73861 cagttctttg gcagacaatt ttgttgttgt gcggatcatt ttttctctcc ttacttattc
    73921 attgatttta aaataaaaac catttttttg aagctctttt acaagttttc gcccctcaaa
    73981 aaagtatatc ttctcttgtt ttacttttct aataccaaaa gaaacagcaa ctttaggatc
    74041 atcagctgaa acgattcgat aagttccacc aggcaattga tccagcttga ctttcccatg
    74101 atggtcgctt tgtactgaaa acggcacacc atttctagta agtgtttttt tcttatgttt
    74161 caaaatgaat gaactaccat ttaccggttt ccctgacgaa tcactaataa taaatgaaaa
    74221 atcaagcact tttttactta atctatactg atagattagt cgtccgataa acactaacag
    74281 tatgactaca gctattatcg ttcctgcaag aataaaccat tgccgcatgg ttctttcctg
    74341 atttcctttt ccttcttctt tttttaccga ttcgttataa ggaatccgat gtcctgtcac
    74401 tagcaaacga tgcgtgttga tcatatacgg cgtacatgta agcaaggtaa ctaagtcttc
    74461 tccttctgaa atcgttagaa cagacgtgtc atctggcagt accacttgta tatttttaac
    74521 ttgataagcc aatttctccc ccaaaacagt caaaataaac gtgtctccgt tttctaaacg
    74581 atctaattcg gtaaataacc gtcgattagg taaaccgctg tgagcagaga tcactgaatg
    74641 cgtcgaattt ccaccaagcg ggaaagaggt tccttgcaag acgcctgctc cattttcaag
    74701 gatcctacca ttgagccgat cataaagtga aatatttaat tggatcttag gtatattgat
    74761 acttccgatc agccattcct ctaattggct ggatgttgta ctttcatttc tgttcttttc
    74821 attgaaagga tcagtaccag gattgaatcc ttggtcagtt aatcgttggt ttttctcctc
    74881 cattttcttt cgctgcactt caatttcagc tgcggtccgt ttttgtactt gttcgatacg
    74941 tttttgatca ataaaactat ttaaagaatc cacataaaat ggatataaag cgatcagtaa
    75001 ccctacgacg atacatatta ataaaaacaa acgaaacaaa agtcgacgag actgtttttg
    75061 cttactctgc ttcacatgtg tcctcccttg caagtttttt tgttctttct tttattatat
    75121 gggttcagga aaaaaataga aaatgaaagc cgatgaggtt gtgaaaaagc tgtcctgcat
    75181 caagtaataa gtacagccca aaaaaatagc tactcatatt ttttgttggg ttgggcttat
    75241 taccgcagat gcaagctttt gaacaccgtt taaggaagag gttgtgaaaa ctgcgttatg
    75301 ctttgagtaa taagagcgct agtcagaaaa tagcttctca tattttctag gctagtgagc
    75361 ttattaccga gaagcagctg attgaacacc gtttaccgag aggtcatgaa aaagctactt
    75421 tgtttcgagt attaagaaaa attctgtttc aaaacaagga gatgcaacaa aacttatgtc
    75481 gcatcctctc tccttagaac tttcacttat gtttttcttg taaaattcat aaatattttc
    75541 atgaattttc taatttcttg cctacctctc gcataggata tatgatgaat ttatctaaag
    75601 tttgcaaagg agttcgacaa ttgaaaaaat atggcccatt tttagcaatt tttttcattg
    75661 ctttggcatt tctcatgcct catttattca cacataaact aattttgggt gctgatgccc
    75721 cattccatta caatcggttc tatgatgccg cgcaacaaat taaatatggg gatttccatt
    75781 attttccttc cctttatgga ttccagcaaa gtggcaggat cgtgaatgcc gtttacggcc
    75841 catttttcgc ttatttacaa ggattgatcg tgttgcttgc aggtagctgg tttcattatc
    75901 agattctttc aaatttcatt ctttatctta tttcaggatt ttctatgctg attttactga
    75961 gatatgtcaa tgttcgaaat tgggtaagtg taccagtagc cgttttattc atgagtacgt
    76021 attctattca atactggtct atcaaccaag gattcactag ctgggggact tgtttttatc
    76081 ctttatgtat gatccctatt gctgatttcg tccttcataa aaagttccct gttatcaaag
    76141 tcgctgtctc agtgggactt atgacacaga tccatttact gtcttcgatc atgttagctt
    76201 tgatgtatat ccctttttat ctttattact tttttaacca gactgaaaaa ggaaaagcac
    76261 tgcttcaact gattaagtcg gtcttgcttt attttgttct gacagcaaat atttgggcag
    76321 gattagctat tgtttacagt gggaataaga ttcttcctcc ctttgttaac agagaaatga
    76381 gtcaaaaggc gatagatctg gatggcagtt attggctcca ttaccctaag gcctttccta
    76441 tattgatatt atcaggtttt ttgcttttta ttttctttca acaaaagaac accttattcc
    76501 aaaaaatcgt gttgtacaca agtcttgttt tcttttttct ttctactagc ttgattccat
    76561 ggacgacatt gatcgaaaaa aatgtgcctt ttattagttt gatccagttt ccatttcgat
    76621 ttttcgtgcc atttacgcta ttgcttctac tttaccttgc cctttcactg aaccagtggt
    76681 ctgaacaaaa gtggttccgt cttttaagta tatttggcat tcttattttt tcagcacaga
    76741 cgatccagaa cttataccag catctggaaa agtgggaaaa tgaaacattt gtcagtcgac
    76801 atacttatct attcgatacg ccggaagaag caaggaaaac attcttcagc aaagatatgt
    76861 ctaccagctt gttcgttttc caaaaaacca cacctgacta tctgccaatc tataaggaga
    76921 caaaagacaa taaatacgac cggtataacg aagaaatact agaaaacgaa acaactttta
    76981 taaaaacaca tccaggcggt cttttgacaa tcaagtggaa aaacactggg gacaaaactg
    77041 ttcatatccc tgttatcgtc tacgatcgga ctgtgctaca gcaaaatgga aaaacattga
    77101 ctgattatga agtaacagat atcgggaccc caatcgtgaa gcagcaaaaa ggaatcaacg
    77161 agctcacgct tcattatcaa acgccaatct atttctattt cattctttct cttactttga
    77221 ttggctggtt taccttgcta tgtttattta tttatcatag atacaagctt ttacgtgctt
    77281 aggcaaaagg gataaataca tccgatcaaa aaactctcca aacggtataa tcgtttggag
    77341 agttttattt taatcagttt ttttatgtta tatgttatat tttttattcg ttcacatcta
    77401 attcgatttc caccccgtag tgatcactga tgattggact atcgatccca tcaaaaatcc
    77461 gttgatattt tttaacctgc attccttcag ggacgaaaat aaaatctata cgcaattttt
    77521 ctgtattttg ttcccaacca tctattttct tttccacagt agctgctttt cctttttcat
    77581 tcgcgacaac atacgaatct tgaagaagaa ggcaactttc tcttacagta taataacctt
    77641 gagagtctac tggattattg aaatcaccta ggaaaaaaag tggtacgcga gtttccaaaa
    77701 agtagttttc caagtttttc cactcaaaat aaaagccact ttttttatct gtccaccaag
    77761 aaaagtggca gctcgagaca aaaatgtcct gatcatctat ctttgttttc ccaatcaaga
    77821 tcttgcgtgt ctgataatct tctttctttt gaaattggga gacggtaagg acctgacttt
    77881 ccaatgtttt tttcgtaagc agtgcatttc cttcttcata tttatcataa ccgatgtggc
    77941 tcatttccca actccaaaaa tactcttttc cgtgttcctt taaaagctga actaaacggt
    78001 aggcaaaatt atctttacgg ataggtactt gattctttac cggacagaac ttcattagct
    78061 tcgcaggttc tacttcttca gattccagta attggttgat ttcttgtaaa gcaatcactt
    78121 cataatcttc taacaggatc ttatctgcta attcttgcaa ttttttctct ggttctggct
    78181 caagccagct atgcgtgttg agtgtcatga atttcattgg ttttctcctt gtcttcattt
    78241 cgaaacaaaa gggttgtgac aaaatttttg tcacaacctc tccagcaaat agtgttctcc
    78301 tgctaactcc tcagtaataa gctcaatgga ccaggagcta ttttttgttt ggctgttttt
    78361 atcacttggt gcagggcagc tttttcacga cctctccact aaacagtatt caaactgctg
    78421 cttctcggta ataagcccaa ccaaacgaaa aataggagga gctatttttg tttggctgtt
    78481 cttatgactt gatgcaggac agctttttca caacctctcc ttacatttta atggagccga
    78541 tcactttacc agctgtcact gtacctaatt gcttgatcac tacttcttct actttatcgt
    78601 ttgtaaatac gatcatgatc gttggatctt tttcttcgtt ttggatcaca tcaagatcca
    78661 tctcagctaa tttcgttcct gttcctactt cttggccttc tttgacagca atctcaaaag
    78721 ctggctgatt catttggact gtatcgattc ccatatggat caaaacttcg ataccatctt
    78781 tcgtttccag cccaattgca tgtttgctag ggaaaatact tgtcactttt ccagcgatcg
    78841 gcgcaacaac ttctcttgat gttggaataa cagcaaagcc gtcacccatc attttttgtg
    78901 agaataccgg atcttttact tcagataaag gaatcacttc tccagaagct gcggaaacta
    78961 gttcttgttc tatacctaag tattgcttac tacctgcttg tccatttcct gtagaaacca
    79021 tttctggctc tggaatctct gctcctgatt gcagcagatc ttcgatatct gatttcaaga
    79081 catctgcttt tggtccataa actgcttgga ctccattgtc tttgacgatc aatcccatcg
    79141 cccctgctcg tttccaggct tcttcagtcc ctactttttc tcgatcattt acacttacgc
    79201 gtaaccgagt catacaagca tcgacatctt tgatattttc ttttcctccc agcaaatgaa
    79261 tgatctggac cacttgctga tctgctgttc ctgttccgct gttagataca acggtttctt
    79321 cactgtcatt gtcgtaattt ccgttacgtc ccggtgtagc aaagttgaat tttttgatca
    79381 agaaatttgc taagaaatac gtaacaacac caaaagcgat cacacacaac acgaagttga
    79441 taagatctcc acctagaccc gctttgatag ctaacggtgt ccgagtcagc aattcgatat
    79501 tcccaaatga atggacccgc aatggcaaga tatctgccat cgcaaatgca gccccttgga
    79561 tcactgaata aatgacatat aatggcacag cagcaaacat aaacatgaac tccaatggtt
    79621 ctgttacacc tgttagaaag acagccaacg ctgctgaaaa atacattgat ttatatcttg
    79681 ctttcttatc aggatcgaca ttacgataca tcgcaaaagc cattcccatc aagatacctg
    79741 aagaaccaat catttgtcct actttgaaac gagccggcgt ccagttatgc aacacaaact
    79801 catattgcga catatcccct gcacctttaa gattcactaa atcagtggcc caagccaacc
    79861 ataacggatc ttgcccaaat acttgtgtcc ccgcctgtgc gcctgataaa atctcatacg
    79921 atccgccaag ctgtgtatag ttgataggaa tcgtcagcat atgatgcaat ccaaatggca
    79981 atagtaaacg ttctaatgtt ccaaataaaa acggtgctag aatcggtgcg ctttcttgtg
    80041 attctgcaat ccataaacca aaattattga ttccagcctg tacgtttggc cacaccacag
    80101 caagaatcaa tgccacgatt gttgaccata agataacaac aaacggaaca aagcgctttc
    80161 cattgaaaaa tgacaaagca tccggcaatt ttctataatt atagtactta ttataagcca
    80221 ttgccccgac aaatccagcg atgatcccta cgaatactcc catattcaaa gctggtgctt
    80281 ccaatacact tgtaaaaaat cctttaacca tgatcttcgt accgaacaga gtgtgggtaa
    80341 atgcatcttc attcgcaagc atgtcacttg tgacaccaaa gatagcccca gtgatccgat
    80401 tgattaaaat aaatgagatc ccagctgcaa atgctccgcc tgctctttct tttgcccaac
    80461 ttcctcctat tgctaaagca aataaaatat gaagattacc aataattgcc caaccaatat
    80521 tttcaattac tccgcccgtt gtgacaagcg gcgtccaatc aggattgatc aagggaattg
    80581 atttccctat actgatcatc aacccagctg ccggcataac tgctaccaca accattaaag
    80641 cctttccaaa tttttgccaa aactcaaaac taaatatctt tttcattccg tttagctcct
    80701 ttacgcaatc ggtttcgtta aacgtattat agcgtgcgtt ttcttttttg taaatgcttt
    80761 attttttatt tttctgtcta taccattcta taaaacctat aatacgtgtg ttcccttcta
    80821 taattttctc ctaaaaattt atttttttaa gcttttttct atgaaatatt ttcttttgtc
    80881 tattgacttg tgcaatcggt tgcgtttatt atgaacgtat aaaacagctc attaggagga
    80941 gaaaaatgaa acagatcaaa cgactatttg ctattgatcc atggaaaatc agcacgacac
    81001 aattagataa aaaaaatctt cgactgcaag aatctttaac aagtattgga aacggttata
    81061 tggggatgcg cgggaacttt gaagaaactt actcagggga ccaccatcaa ggtacttatt
    81121 tggcgggtgt ctggtatccc gataagacac gtgtcggctg gtggaaaaat ggttatccag
    81181 aatactttgg aaaagtgatc aacgccttga actttatcgc gatagatatt tcgatcaacg
    81241 atcagctgat cgacttggct tctttggaac cagaagactt ttactgggaa ttagatatga
    81301 aaaatggtgt attatctcgt acattcacaa tcactacttc tactaataaa gtacgcattt
    81361 ccttcgaacg ttttctgagc attgtcaaaa aagaatcagc ttatatctat ttaactatag
    81421 aaatgcttga aggtagcgga acagtcaaac tcgtatcaaa attggatgga aatgttcaaa
    81481 acgaagacag caactatgat gaacattttt ggaatgagat tgatcgtgga actatagaag
    81541 aaatcggcta tttgacgact aaaactattc caaacaactt tgggattgaa caatttactg
    81601 ttactgcagc aatgcgccat ttcgttaatg gaaaatcagt catccctgac tatcacgaag
    81661 atactttagc attacatggt tgcttgtctg cagaattatc tcaaggtgag acatggtcag
    81721 tggaaaaaga aattatcgtt cttactagta gagatattcc agaagcgcag caagcagaaa
    81781 aagctgtctc agaattaacg aaccagacaa acaattatat ccaagcaaaa gaagagcaaa
    81841 cagcggcttg ggcagaacga tggaagcttg ccgatgtggt catcgaagga gacgaagaag
    81901 cacaacaagg tattcgattc aatttgttcc aactattctc tacttactac ggcgaagatg
    81961 aacgattgaa tatcggcccc aaaggattca caggagaaaa atacggcgga gccacttact
    82021 gggatacaga agcgtatgct gtccctcttt atcttgcttt agccaaacct gaagtaacta
    82081 agaatctgct gaaatatcgg cataatcaac tgccgcaagc aatccacaac gctcagcaac
    82141 aaggattaaa aggcgcgctt tatcctatgg tcaccttcac tggtgtcgaa tgccataacg
    82201 agtgggaaat cacattcgag gagattcacc gaaatggcgc gattgcctat gcaatctaca
    82261 attatacgaa ttacaccggc gatacggaat atttgaaaaa tgaaggactg gaagttttag
    82321 cagaaatcgc acgcttctgg gcagaccgtg tccatttttc aaaacgagca aataaataca
    82381 tgatccacgg tgtgaccggc ccaaacgaat atgagaacaa tatcaataac aattggtata
    82441 caaatacgat cgcagcttgg gtcttgcgtt acacgcgaga aaattattta acttatcaaa
    82501 aagaagctgc tatcactatc agcgaagaag aactagccaa atggaaagat atcgcagaga
    82561 acatgtactt cccagttgac gaagaattag gaatctttgt ccagcatgac acattcttag
    82621 ataaagatct catgcctgta tccgatattc ccacaagcga tcttcctctg aatcagcatt
    82681 ggtcttggga caaaatcctt agatcttgct tcatcaagca ggcagatgta ctacagggga
    82741 tttatttctt caatgatact tttacaaaag aagaaaagca aaaaaacttt gatttctatg
    82801 aaccaatgac tgtccatgag tcttcccttt cgccaagtat ccattcgatt ttagcagcag
    82861 aattaggaat ggaaagcaaa gctgtagaaa tgtaccagcg aacagctcgc ttggatttgg
    82921 ataattacaa taacgacaca gaagacggct tgcacatcac ttccatgact ggtagctggt
    82981 tgtcgattgt ccaaggattt gctcaaatga aaactgccca tgatcagttg agattcgcac
    83041 catttctgcc aaaaacttgg aaagcttatt ctttccatat caattatcgc ggacgtttat
    83101 tgttcatctc agtcacagat gaacaagtta ctttcaagtt attagaaggt tctcctctag
    83161 aaatttacgt ctatgaacag tcttattctt tagcggatcg tctagaaata acgctaagaa
    83221 aggaggaagc aaatgtttaa aggggtattg tttgatttag acggtgtcat taccgatact
    83281 gctgaattcc attatcgtgc ttggcgaaag cttggtcagg aaatcggcat tacgatcgac
    83341 cacacattca acgaacagct aaaaggcgtc agccgagaag actcactctc tttgctttta
    83401 gcttatggcg gaaaagaaca ctcttttaca aaggaagaat ttgcagaatt agcgaaaaga
    83461 aaaaacgatt attatttaga gatgatccag acgatcgaac caaaagatgt cttccccggg
    83521 gtcgtgcctt tactggattc tttaaaagaa gaaaaaatca agattgctct tgcttctgca
    83581 agtaaaaacg ggccattcct acttgaaaaa atgggtctta caccttactt tgatgctatt
    83641 gccgacccgg cagaagcaac aaacggaaaa cctgcgccag atatcttcct ccttgcagca
    83701 aaagctgtcg gactaaaagc agaagaatgt atcgggatcg aagacgcgca agccggtatc
    83761 caagccatcc tctcaagtgg cgctcaacca attggcgtgg gacgtgctga agaccttgga
    83821 gaggagatcc cgcttgtccc tgatacgact tttcttacga tcgattactt gaaagaaaag
    83881 tggcatgacc atggataatc cagagatctc cgtcgtacca gttccagaga ctgaaataaa
    83941 gaaaatcaca ttgaagaacg actacttaga agtcgttctt ctcaattacg gtgcccgcct
    84001 gcaccaaatc ttcgcaccag acaaagaagg aaaatcagaa aatgttttat tgtcttacga
    84061 tcgtttcgaa gatgttctaa cagacaaaag cttttttgga gcaactgtcg gacctgtagc
    84121 cggaaggatc cgggatgctt cttggggtga gcatagattg gagaaaaact gcggatcaca
    84181 ccatatccac ggtggcacga aaggctggtc tttccaattt tgggaagtag aagttttcaa
    84241 aactccatca tcaataggtg tggtctttta cttaaaagat gaattttcta cctatccagg
    84301 accaatcact gctacgatca cttaccgttt aacaaaaaac gaattagaga tgacaacctc
    84361 tgctagtagc cttgttgaaa ccatctgcaa tccgaccaac catgcctact tcaacctttc
    84421 aggaaatgga acaagagaca tctatgaaca tcagttaacg gtctttttag atggtgtgct
    84481 tgaattagat caagaaaaac tgcctactgg aaattggaca aaaaaagaaa aactgccaat
    84541 cgactttaga aaatccccaa cactgcaaga gatccttgca tgttatccag atggactaga
    84601 tgatgtattt cttttgcatc atcctaggct ttccaaaact tccttacaat tattcgagaa
    84661 gcattctggt cgccaaatga ctatagcaac ttctaataaa agtatggtat tattttctac
    84721 gactggattc gaagctgatt tctctgtcaa tggaaaacag atgcattcaa actacggatt
    84781 agcaatcgaa ccgcaagaaa tccctgatat cgttcatttc cccaaatttg gatcgatcaa
    84841 cctccatcct ggtcaagaac ggatcagtca gacgatttat cggttctctg cacaataaca
    84901 agagaaaggt gtttttatca tggctattac cgtaaaagat gtggcgaaaa aagccggtgt
    84961 tgccacctcg accgtctctc gtgtcatcaa cgatcatcct agtatttccg agacaacaaa
    85021 gaagaaagtc cgaaaaatta tggatgaact aggttatgtt cctaacatga ctgcccgcaa
    85081 tctaggaaaa cgcatttcca gtgccatcgg cgtaatctta ccccctcttg attcaaaaga
    85141 gcggatcggt aacccatttt atcttgagat catggaagca atcaacgaag aagcgcggaa
    85201 ttatgatatg actacagcaa tcgctactgc taaaaatttt gaattgctgt tagagaacgt
    85261 ccagcgtatg catttacaaa aacaagtaga tggttttatt ctagtgtatt cagatagtca
    85321 agatactgtc attgattatt tataccaaaa ccacatccct ttcactttga tcggacagcc
    85381 ttatcatcat gagaacgaaa tcgtttatgt agataatgat aaccagcttc taggtaaaca
    85441 agcaacagaa tttttgatcc agaatggaca taagaatatc ctgtttgtga caaacacgac
    85501 tcatgaaagt ttgtatttcg aacgatattt cggttatcaa aaagcaatga tgatggctgg
    85561 tcttcctgcg ttatccagtg tagtactaga gcatccggag gattatctgt cctttgagaa
    85621 aacgttgaaa gaaaacgaag ccacagcatt ggtggtcatt gacgatatct tcgcccttcg
    85681 cacgatgcag ttggcgcaaa tgtatggcta tgtcattcca gagacactct ccgtcattag
    85741 cttcaacaac tcgatcttct caacattaac acacccttac cttacaagta tcgatatcga
    85801 tatctccgaa ttaggacgtg tcgctatgca aaagctgcgc gaattgatcc atgaagaatt
    85861 gagcagtggc gtacgtttgg tcatccctca tcgcttgatc aaaagagaga cagtcgttcc
    85921 tttagaaaac ccatactaaa tagctgactc actaaatacg ctgaccattt atcctatggt
    85981 cagcttttta tgtaaaagaa gatactactt ctaacacatt gtttatctgt aaaaaagagc
    86041 gtgggacaaa agtaaagaac acttttgtct cacgctctaa acacgtataa acggcggaag
    86101 cagaagcaac tccttcggaa ataagctgaa attcacaaaa atttaaaaag caattttctt
    86161 gagtttcttc ttatttcttg gagttaaacg cttctgtccc agcctctttt ttccttcctt
    86221 caatttttta cacgtcgacg attcaataaa aaaccgccta atattgtaaa gacaggtgca
    86281 agaatcgaga aaaaggcgaa tggcaagtaa tgcaacgcgc taactttcat cgttcccata
    86341 atgaatgtgc cgctgactcc ccacggtacg agagaattga cggtcgcacc tgaatccgct
    86401 agtgttcgtg tcaaataggt ttttgataag ccaacgtcat caaaagaacg cttgaatgtt
    86461 tctcctggaa gaatgatgga cagatactgt tctccaacga tcagattgat tccgatacag
    86521 ctcaaggcag taaacccgac taaacgagaa ggtcggtcca tcttttcttt taattcttga
    86581 acgatggtat caacgatcag atatttgatc agtaacccac ctaatgccaa tgcaagtaaa
    86641 atcaaactag cagaacctaa catactcatg atcccgcctc gagaaagcag ttcatctagc
    86701 tttggatcag gtgtatttgc gacataacca ttcatcaaga tgtctgctgc ttttccgacc
    86761 gtcaaacttt tctcatggat aaaagaaaga acgagagcag ctgtcgatcc cgctagtaat
    86821 gtagggatag ccggaatttt tttgattgcc ccccccaaat aaaataacta gtggaatcaa
    86881 tgtccaagga gagatccaaa agctcgcttt catgttttgg atcatttcat tgatactagc
    86941 tagatcggct gaatgactgt tatgtcctaa tatcgtataa aaaatcaacg aaaggacgaa
    87001 tgctgggaaa tccgtataac gcataccagc gatatgttcg aatagattaa ctcctccaat
    87061 acccgctgcc aagttggtcg tatctgataa aggcgagcag ttattcccta aaaaggcacc
    87121 ggaaacgact gcgcctgtag tcattgcatc attgaatcca agtaaatgac cgatccccaa
    87181 aaaagcaatt ccaatcgtcg aaatcgttgt aaatgaactg ccgacagtca ctccgacaat
    87241 tgcacaaaca agaaatgctg tcggtaaaaa gaaacgcaca gaaacaagtt taaatccata
    87301 aaccataatc gtagggatgg ttccagataa aatccatgaa gcaactaaga caccaatcaa
    87361 aagaaaaatc aggattggaa tgatccctgg agtgattcct ttgatgatcc cgtcatggat
    87421 ctcatcccat gtgaactttt taaatctgcc ataaaacaac aaacacatga aagctgcaag
    87481 gatcgggata tgtggcgaga gctggaatcc gatgatcagt actcctagga gtgccaacaa
    87541 cacgatcaat acagcgatac tttcttttaa agaaatattt ttattcatcg tcgatctcct
    87601 atttcaaatg aaaaggccct gccatgaaaa aactattcac ttggcaggac ctcctactaa
    87661 atcagcgaca aaacgtcggc tgaaagactt atttttttat ttttcttcta aacttttttc
    87721 tacctcaatc ccccaagaat ctttcttgaa gtgattgatg atcaatggaa taacgaacat
    87781 gaccactgtg atagctgcta ctaataatgc atcactcaat gtcgctgtac ctaatgtagc
    87841 aaatacgaca acgatgatag agaagatcag catgcagctg actacccaag ctaatccgtt
    87901 tccgttttta ccaattcggt aaggacgttc gaattctgga tgtttcttac gcattttaag
    87961 caatgaaaca gcaatcaaaa tgtacacgat acaataaata acagttgtag catttgtaag
    88021 tgtcaagaat acagcactta cgtcatccat tacaccataa agcaaagcaa ataatgaaat
    88081 aacgattgat tgtgttagaa cgacatttct agatacgccg tatttgtttt ctttatggaa
    88141 tccgaatttt ggtggaagga atccttcacg agctacttgg atgattgttt ttgatggtcc
    88201 agtaacccaa gctgataatt gtaaaagcac accaataaat accatgaagc tgaagatatt
    88261 tccgatcact tctggtaagc ctaggatttg acagtcaatc aagataggct gcgtgatatt
    88321 tgctaattcc atttttccat ctggtacgac atttgctaca agcatcgcat tgatgacatt
    88381 caataaaact aatccgatca aagcgataaa tacgcctttt gtataatttt ttgttgcgtc
    88441 tttcaaacga ggcatgtaaa cagaactcat ttcgatccca acaaaaataa atgtgatacc
    88501 agctaagtat ttcaatgaat caatatgttc caagtcaggg aaagcttttg accatgaaaa
    88561 gtcacctaga tagccgtttg agactagtcc gactttgaag gctgccaaaa cacctaaaac
    88621 gaacatgatg actactggga tatatacccc tagccataca ccgatgttcc cgccgacttt
    88681 tgccatatcg aatttcaagt tcaagatcgt gatgatccag tagataacta aaatacaacc
    88741 taaaacgaac cagtgattat tgccaagttc tacattacca aatgtgtttc ctaacaatgg
    88801 tcctaaagta gaagcgacca ttaccatacc tgggaacatt tgcacccata atagccatgc
    88861 aacgacaaat ccccatttgc tgcccagtgc tgtttttacc cataactgag gaccgccttc
    88921 ttgaggaagc atcgtggaaa gctcaccgga aaccattgat atcggaccgg caaaaaacaa
    88981 aactgcaaaa attgaataaa aaatcaatgt ccaaccgact gcggctaacg taggaatact
    89041 ccgaaccgtt gcacacagtg ccattgtcag accgataaag gtcccaagac ccattttact
    89101 tacttcagat ttactcaccg ttgacactct ccttgatttt ttggataaaa taacggtgtc
    89161 tttgaagtag tttcagcaat aaacgaaaca attcagcgaa tatttgaggg gattctttga
    89221 gtttattgct tgaagggttt cttcaaagac aacctcaaaa caaagggatc gaagagctta
    89281 ggtctcccct tgctcttcag atccaaacat gcgtcagaaa cagttagtat tcaagctgtt
    89341 ttctaacatg attaccttgc ttattttgct tcgcttgcca ataattggtc tgcgtagatt
    89401 ttttccaatt tttcttgaag agctgctttg attttttcag catattcttc aaagtgttct
    89461 tctttgttca tgtatggtgt cattacgctg gcacgcaata cagttacttt tccggcacgg
    89521 ttccattctt catctgagaa tcctagttgg ttcacaaatt gtaatgggct gttgccatag
    89581 tctgggatag caaagtcagt atgtgaagtt aagaactcat taccgtaaat gcttcctttc
    89641 acgtatgaag aataatcata tacgtcatgg ttcaatttat tcattgcaac taagtcatcg
    89701 ttgccttttt ctttgaatac atagtctacc atattgaaat ctggataagt taatggatga
    89761 acttcgattt ctttgtctcc tactttaaat gacaagtcat tcaagaagtt gtagaaacga
    89821 tgtgcacctt cgattgatgc acccattaat ttaccatatc ctgtgacatt caaaggtaag
    89881 acatggtgtg ctgcccaaac gctggctgct gttgcccctg cttttgaacc ttccaagata
    89941 taagccccaa gtaatgctgg gatatctgcg cctttttcaa atacatatgt cgcaaagtaa
    90001 gagataacgt ctctcatgcg gatatctttg atgacgatac caccggcaga atatggaaca
    90061 tagcccattt tatgtgggtc aatcgttaca gattctgctt cttcgattgc tttatatgca
    90121 ctgtgtactt cttctaagat ataatctttg ttttctgtaa agacattgta tttgtaatga
    90181 acatctttta aatcttcaaa tggaatgaag ttgttgtctt cgtctaagaa aatcgcacgg
    90241 ccgtatccgc cataagcagc atctacgtgt aagtagaagt aaataccgtc tttttctaat
    90301 acgcgacgca atgcaacgat tttatcgata ccgtcgattg ctccttcttc tgttgatcct
    90361 acaacaccga ctacacctag gattggtgtt ttttcagctg ctagaccacg aacgattttt
    90421 tcaagttcgt tgatgtccat gcgatagttg tggtcaactg gcactggaat cacttggtct
    90481 aaaccgatac cgatgatgtc ggcagctttt agccatgaat agtgtttagt ttgtggaacc
    90541 aaccattttc ctaatttttc taaatgtttt ccgctacgtg ctgagtgagc tttgatttcg
    90601 tcgatttttt ctgggacgct gtctaacaga ttcatgattt cttctgttga caagttcatt
    90661 aattcccaat cgctttttcc agcaactagt tcaggtgtca cttctttcat tgcaagcggc
    90721 aatgatttga tgttgcgggc ataccaaagt ccttctaagt ttgctaaaga accatcagca
    90781 acgatgtggc cccagccatc tttatagctc attaattttg caaattccat tcctacttct
    90841 tcttccattt ggcttgttgc aggagaagat tcataggcaa cgttattacc attccatagc
    90901 atagcaaaat tgtacgctag taaagatggc atcaatgttt cagagttcat atgaccccag
    90961 taacgtccgg cattatgcca aggaacggaa tgggtacgca tccgcgctga aatttctgat
    91021 agaacatcct ttgttttatt cacagtgtgt tcaaaactag cactgctttt ttcttctggc
    91081 gtaataatag gcatgtcttg aggcatgtag ttttgacgcc agcctaaatg ttcatccacc
    91141 aattcattca acaaagcttt atagatttgg ccgttctcag ctttgtcccc aatgaatagg
    91201 gcatttaggt ttagatcttt cgacaatgat tcactcatag tgaaaccctc ctaaaaaaat
    91261 atttaaattt tgtcgagccc tacattacac ctgttcttct attctgtaaa ctaagttttg
    91321 gcctgatttt taatcatatt ttaatatgta tcaattatcc gaattgttca cacttttgaa
    91381 ataattaaaa aaaacgaggg aatttacaaa tgtaaactcc ctcgcaaaga ttgtattaac
    91441 gacaaccagc gttctatttt aggatgggtt tcaaaattgg aatgttgtaa tagtatttcc
    91501 ctttttcaag gtaaaaactt actaaattct aatcaattac tttggccaaa aagtaatttt
    91561 tcttaccttt tcgaataacc acaaacttac catcgaattc atcggatgga tttatgacaa
    91621 aatttaaatc ggtaacgcgg tcaccgttaa tacttatagc tccgtttgaa acatcttcac
    91681 gtgcttgacg tttagatggt tcaatttttg tggaaacaag cagttccacg atattttcag
    91741 gtgtgcttga aatttcaacg ttcggcattt taccgaatcc ttgcgcgatt tcttccgcat
    91801 ttagttcttt aatatttcca gagaacaatg cttgcgttat tttttgcgct tctttcaagt
    91861 cttcttcact atgcacaaat cttgtaactt cttctgccaa acggcgttgt gcttcacgtt
    91921 tctcaggttc tgtctctact tttttcgcta agtcttcgat ttcttcttga gacaagaaag
    91981 taaagaattt caagtatttc actacatcgc gatcatcttg attcaaccag aattggtaga
    92041 actcaaatgg tgaagttttc ttcggatcaa gccaaacggc accgcctgca gtttttccga
    92101 atttcgttcc gtcagccttc agcatcaatg ggatcgttaa accgaacgct tctgcttctg
    92161 gtccttctaa ttttcggatt aggtctaatc cagctgtgat atttccccat tggtctgctc
    92221 caccgatttg caattgcaca tcgtatgttt tatgcagatg caaaaagtcg atagattgca
    92281 ggatttggta agtaaactct gtaaatgaga ttcctacttc caaacggctg gcaacgatat
    92341 cttttgctaa catcgtgttg atgttgaagt ttttaccgta gtctctcaaa aattcaagta
    92401 aagagatttt tgacaaccag tcgtagttgt tcacaaatgt gatatttgca tctttaccaa
    92461 acaattttct catttgattg gaaagtgcgt ccacgttatg ttgcacttgt tccatcgttt
    92521 gcaacacacg ttctgttttg cggccgcttg ggtcgccgat cgttcctgtt ccgccgccaa
    92581 tcagaatata tggatgatgg cctgccaatt ggaatctttt catcatcata aatggaatca
    92641 aatgtccgat atgcatcgaa tcaccagttg gatcaacgcc gcaataaagt gaaatgctct
    92701 tttcttcaac gagctcgcga agtctttctt cgtttgtttg ctgattaatg gcgtcgcgcc
    92761 aagttaattc atcaataata ttcattttac tgacctccgt gtagtttttt tatgaaagca
    92821 ggaacctgct agcatgtgta attaattatt tcttcaggat aggataggaa ataaaaaaag
    92881 tcccttggca tataagccaa gggacgaaat ctcgcggtac cacccaattt gtatgtctag
    92941 atatccaaca tacctctcga acatttaacg ctgtcgcgtg gcaatcactg ccaaagactc
    93001 ctgaaatgta attcgcttta aagcatgtac tggtttgcag cgaccaccag ctttctgaaa
    93061 cattggcttt aacaactact tcgtttcgat cttcgtcttg ttattattaa tatgtgtcta
    93121 tcatagagcg caactttttc tttgtcaaca gaaaaaggat atttttttta aattcctcat
    93181 tttttctttt ttgaatccgc tctaattccg aacattttat tttcaattat tgttaaaaga
    93241 aataactttt tctgtatttt ttctgcaatt tatcgagaag tcactttact ttgcctctta
    93301 ttctttcttc gttacaataa ggaatgggac aagtaaaaaa atgaaaaagc aagggacgag
    93361 gtatatggaa aaaaagcaaa aaattatttt aggagccact tctgctttaa ctatcgttat
    93421 tttaattcta agtttgtttt ttgtcatccg atcatctaca aaaaaagaac caatcattcc
    93481 tgaaaaaaaa ataacagaaa aagcaaaaga accgacagat gataagcaac aactagttac
    93541 tcaagcaaaa aatctggctc aaagctacga ttatgaccaa gcgattgcgt tattggaaaa
    93601 agatagtaag aacggatcta ctgaaacaca acagcttctt caaacactaa aaaaggagaa
    93661 agaacaactg atcgactggt ctgatcctac tcagatctct catgtctttt tccacagctt
    93721 gatcgtggac ccgcaaaaag ccttccactc tcaacaggca caaggataca aagattatat
    93781 ggtgactgtt gaagaattca accgttcgat cgaacaactt tatcaaaatg attttgtttt
    93841 agttaatttg aatgatttga tccaaaaaga cgaacaagga aatctttcct ttaacgggct
    93901 tgcgctacct gaaggaaaaa aaccattggt tctttcacaa gatgatgtca gctattatga
    93961 atatatggat aattccggtt ttcctagccg attggtcgta tcaaataaca atgaaatcaa
    94021 aaatgtctat aaagagaaag ataaagaaga aatcggtgac tttgacatgg ttcctctgat
    94081 cgatgccttt gtcaagaaac atcctgattt ttcttatcga ggcgcaaaag gtaccttggc
    94141 cctgacaggt tacaacggag ttttaggtta tcgaacatca aaatctcaat atggagacaa
    94201 tgaaaaaaca aaaaaagaga ttaaagaagc taaaaaagtg gcggaacagt tgaagaaaga
    94261 cggctggagc tttgcttccc atacatgggg tcacttgaat atgactcaag cttcactaga
    94321 agatgtaaaa aaagacaatg aattgtggca gcaagaagtt gcacctatcc taggaaaaac
    94381 aaatattctg atttatccat ttggtgcaga catcagcgac tggcagcctt attcagcaga
    94441 aaatcaaaaa tttgcttact tgaagagtca aggtttcgat attttctgta atgtcgatgc
    94501 ttctacacca gcttggggac aattaggtac ggatttctat cgaaatgctc ggatcaatat
    94561 cgatggcatt cgttttcaat ctgatttaga cggaaaaaat cctattcttg atccattcat
    94621 caatgtccat gatgtctatg acaaagaagc acgcgaatct gcttgatttt acgtcattta
    94681 tgaaccaaaa aagccgaact gacattttat cgtcagtttc ggctttttta tgctttattt
    94741 cttcttcggt gcgattccct tgatcaggac ttctgtccat tctgctgtat atggaagcag
    94801 ttttgcgtat atctccggct tagaaattcc ttctaccatt gcttgaaaat agaggatcaa
    94861 gaactcatcc gaatatttca aatccacttt tccttctttc cgccctcgat ggaaaagatc
    94921 aagcatgata ctgaaacttt cttgcgtata cgcatccatc gcgtcagaaa attctttttt
    94981 ttcttttttt gtatagtatg tcatcaaatc gatataaaat tgtttgttca ctcgattgag
    95041 ataacggatt ttgttttcac tcatggcaat cagtgtttct tcaaatggaa gattttccgc
    95101 aatcaacgct ttcgcttctt gccctaaatc attcataaat gcaaaaaata cttcataaat
    95161 cagcccttcc ttgctgccaa aatatttaaa aatcgtcgct ttacttacct gagcgttctc
    95221 agctacctta tccattgtca ctccagcggt tcctatgtct gtgttcatca agtcaaaagc
    95281 tgcttgtaaa atctctttct ttttctcttg tgctctcttt tcaaaaccgt tcatttgtag
    95341 agcctcccgt aattttaaac ttttataata tatatagttc aaatttattc tgaggtttat
    95401 tataactatc tattgagaaa gtatcaagct agcaattcct tgtttatgaa ttcattgaca
    95461 gaaatttata aaaagaatat tatgtactaa aataataaaa aaagttttat aaaaaggtat
    95521 aaaacctttt tattaaacta tttaatcttg tttagtatat atttttagaa aaaggagtgg
    95581 ggtttttatg gcagaaatcg tcaaagtcac acatttgaaa aagagctttg gtcgtttcga
    95641 agctttaaaa gatgtctctt tcaccgtaca ttcaggtgaa gtcgttggat ttatcggacc
    95701 aaatggttct ggaaaatcca cgacgattcg gacactttta gggattataa aaaaagacgg
    95761 cggaacggca acgatttttg ggcaagatgt atgggaagat agtttatcta tccatgaacg
    95821 tctttcttat gttccaggcg atatctcttt gtggggaaat ttgactggag gagcgatcat
    95881 cgatctcttc atgaagcttc atggaaaagg gagtgctcaa aaaaaagatg aactgattca
    95941 acgtttctct cttgatccta agaaaaaagc aaaaaactat tcaaaaggaa atcgccaaaa
    96001 agtgggcttg attgctgctt tggctgttga ttcggatctc tatttatttg atgagcctac
    96061 ttctggttta gatcctttga tggaaacgat tttccaagaa gaagttgaaa aattgaaaga
    96121 acagggcaaa tccatcctac tttcttctca tattctcagt gaagtcgagc gactagcgga
    96181 taaagttgtg atcatacgcg aaggaacact cgatgaagaa ggaacactcg atgaattgcg
    96241 tcatttgact cgttcgacca tcactataga aacagaagca gagaatagtc acttagcaca
    96301 attgaacggt gtccatgact ttgtgcaaaa aggtcacctc gctcaatttg ctgctgataa
    96361 cgaagctttc gatgtgattt tagctgaagc gtccaaatta ggtgtgaaaa aatttgaatc
    96421 tattccaccg actcttgagg atttattcat gagacattat gaaggatgag gaggaagcga
    96481 aatgactgat aaattttcac gctggtccac ccttttttct caaaacctta gccgtgactg
    96541 gaaaaagatc ctgatatggc tagtcggtgt cactgctttt tctggtggtt ttgtccctgc
    96601 gtttgaagaa ttgacttccg gacaaggatt agctggatta tacgaaacct tgcaaaaccc
    96661 ggcaatgatt gcaatggtcg gaccaactcc agcttcgaat gctgctgagt atactttagg
    96721 agcgatgtat gcaaatgaaa tgttgctttt ttgcagtttg tttgctgctg tgatctctgt
    96781 tttacacgtg gtgagccaaa cgagaaaaaa agaagaactt ggtctgattg aacttattcg
    96841 ttcctttcga gtcggacgtc aagcaaactc tttagctgtc atcgctgaaa gtattctgat
    96901 caatttgctt ttagcaatat cgatcagttg tacgatgatt tttttccaag cggattcgat
    96961 cactgcagaa ggtgcttggc tttttgggct atctgtaggt agtatgggga ttttggggag
    97021 tgccgttgca ctgtttgctg cacaactgat gccaagttca gccagttcga atggtctgtc
    97081 tttagcgttt ttaggtggac tttaccttct acgagcaata acagatgtag ctgattcctc
    97141 cctttcgatg tggaatcctt taggctggtc ttatttgacc tatccattta caactaacaa
    97201 ctggattcct ttgctttatt tgtttttgtt cagtctaatc ttgataatca gttcatttgt
    97261 tttagaggaa catcgagatt tgaacaccgg ctatatcccc gaacgtgaag gaaaaccgta
    97321 tgctaaacgt tctcttttat ccttgcgtgg tttattattc tatctaaata aagggatgac
    97381 aatcagttgg cttatcactt ttggtttgat gggggcggca tacggctcta tctacgggaa
    97441 tatgcaacag tttttagaaa gtaacgactt aatgaaacag atgtttatcc aatctggcgt
    97501 ctcaattgaa aaaaacttta caagcacgat catggtcgtc ttgatttgtc tagctgctat
    97561 tttaccaatt gctagcatca atcgtttatt tacagaagaa acccacggac gtatgaatca
    97621 gctgttcgca acaaaaattt ctaggaacca actttattgg accaatatgt tactagctat
    97681 tctatttgct atattggcaa tcctgattag ttctggtgca ctagggcttt ctgctttggc
    97741 ttcgatgaag gatgcgaaag acatggatct attgatgttt cttaaagccg ggttcaattt
    97801 cctgcctgcc gttttagtgt ttatcggaat tagtggcttt ctattcggat ggcttcctcg
    97861 aatcggtaaa cttgcttata tctacttagc ttactccttt gcactcaatt actttggcgg
    97921 aattttggat ttaccagaat ggttttccaa aacagctgtc cctagctggg ttccacggat
    97981 gccaaacgat tcttttgatc tttccgtgtt ccttacgtta tcatgtatca gccttgcact
    98041 gttcgtcctt ggttctattg gttataggcg aagagactta ctagaaggat aataaaaaag
    98101 catgtacaat ttcatgctag cctccaaatc tgggtcaaaa atccaacatt tggaggtcat
    98161 ttttttattt acaagtcttc taactgctct ttatcaatga tccagacttc tcgattcttt
    98221 ctttttacat aaccattctc ctctaataat ttaaattttc tagataaagt ttcgggggtc
    98281 gtaccgataa atgcagcaag ttctttcatt ttcattggca ggaaaaagtg atccttccct
    98341 gtcgctttag ctaagtcaag cagatagaca gcgactcgtt cttctacttt ttccatcatc
    98401 aaaaaagttg tctgctgctg tacttttgtt aatttctcaa cgttgattgc taaaagtttc
    98461 agactaaggg cgggataatg cagtaagagt tccgagaaat ctttttgtct caatatgcaa
    98521 atttccgttt tttctagtgc ttcgccaaat aaagactcat ttggaacgcc tagcaactgg
    98581 ctctctccct catatccgcc cggctctatt actcgtaaaa gctgttcctt tccgctagca
    98641 gataattgat acactttcat actgccggag gccacgatca ctaattgagg ttctccattc
    98701 ggcgcaagaa tctgttctcc tttttccaca tagtgatgtt tgacaagtgc gtgtactttt
    98761 tcttgatctt gctgtactaa gtgattgaac aaaggaacaa atgaaacaca taaatgatca
    98821 tgactcataa tctctcctcc ttctaaacag ctatttctaa taaagaaaca taacttccct
    98881 tattccaact gataattttc ttttatcata gcataaacgt caagcgaacc agataccagc
    98941 aaatagagtg gatttctttt tgtcccttgc tttattttcc ttcttttgag accttaagta
    99001 attgattcct atcaattttt taaatattta ctttttgaat aatcaaaaac aaaccttcac
    99061 tcgcaagccg agagtaaggt ttgtttttcg cattgcttat ttcgtgttgt ctattgaaat
    99121 ttttccgcac ctagcttttg atatagtggt gctagttctt gtaaggtttc agcggttatt
    99181 tgctcaacgt gttcgatttc ttgcggatag aagaatagtt tacccatttg aaaggttcgg
    99241 tctctcatcg cttttttcaa ctcttcttgt ttctttgtat cggacaaata gtcagacaaa
    99301 gctaagtggt cgtcaagttc atgttctggt tgcggccata tgtaataatc cttgatatcg
    99361 actgttttgc tccactcttt cagtatcgca agcaactggt tatacgctgc aatgctacca
    99421 tatcgttctt cgcttttata atgttggtac atcaaataga tttggtattg tttttgattc
    99481 aacaaaactg ctagacaggc attctcgtct tgacgagatt cgcttcggta cgcgctccaa
    99541 aaatgactgc gtaaattcca gccattcgtc cagctttcga ttttaggttt gctcatgccg
    99601 tacatatcag gcaaaagtgc agctgtctgg agctgaatct ctttccattt ttgccagtgt
    99661 tctttatatt ctttcttgat ttgttcaatc ttatctgttg gatggctctc tttgagctgt
    99721 ttgaatgcgt agattggtcg atcaaacaac tgataatctg attttccaag ttccattgtt
    99781 tcgcctcttt ccgttatctt ttgtattcta cctgaatttt gcgatatgga caaatagagg
    99841 ttgtgaaaaa gctgttctgc atcaagtcat aagaacagcc aaacaaaaaa ctgcgatgag
    99901 catcaccgca gttttattga acttaaggtt gattgatcac atctaaaagc gttgaaaata
    99961 aaatggcact agaagcagct cctgggtcga tatgtccgat tgcacgctct cctagatagg
   100021 aagctcgtcc ttttttagct accaagactt tggtgtgttc ttttgcctgg tcaatgattt
   100081 cttttgttaa attccctgcc ttcaatgcct ctgtgactgg cagccaaaca tctaacatcg
   100141 ttttatcgtc agcttctgcc tttcctcggc tttgaatacc cgctgttccc tgctcgatca
   100201 cttcgcctaa tttttcttga gaatcaatag aatcgacctc ttttgtcgct ttcatcatgt
   100261 tcatgaatgc agatccgtat aacggaccag aagccccacc gactttcgat atcatcgcca
   100321 tagagaatac tttgaatgta tcgctgattg tttcaggatg atcggcttga aaagcttctt
   100381 cataagctga aacccctctt cccatgttat ttccatggtc tccatcgcca atcggggtat
   100441 ctagatcact gagatattgt ttgttctgat tgattgcctc tgcaaattgc gtgagccatt
   100501 cttggatttc ttgaacggtt agtttcatat tatcaccctt ttatcttgag attttttacc
   100561 atgaaatcgt ctgtacattg ctttctaaag aatctttcca ttgtgtctcc gtcaagtcga
   100621 tcagtgttag agaaagacct tgcatatcta gtgaggtcat aaaattaccg acttttcgga
   100681 aaactacatt gacgcctctt tcttccaaca gagctaaaac atcattcatg aacacgaact
   100741 gttccatcaa aggcgtcccg cccattccgt tgactagtac acctgcttct tttggtaaat
   100801 tcgagtaatc atctaaaatc ttagtaacaa gttcctttgc cagtacttta gaaggctgca
   100861 tcttttctcg acgatagcct ggctcaccgt ggataccaac accatactcg atctcatctt
   100921 ctcctagttc gaatcctggt ttccctactt ctggtacagt tgctgctcga agcgctagac
   100981 cgatcgtctt agttgcctgt acgacctttt ctcccagttc tttcaactca gctagggaag
   101041 caccgtttct tgctgcatcg cccacgattt tgtgtacaag gacagtacct gcaactccgc
   101101 gttttccagc agtatacgta ctattttcaa cggcgatatc atcatctacg atcacacttt
   101161 ctacttcaat atcgtccata gcagctaatt cctttgccat atcgaagttc aatgcatccc
   101221 ctgtataatt cttaacgatc agcaaaactc cttttccact atcggcttcc ttaatagccg
   101281 tctgaatctg atctggagtt ggagaagtaa acacatcacc aagcaccgct gcacttaaca
   101341 tcccttcccc tacaaacccg gcatgggatg gttcatgtcc gcttcctcca ccagaaacca
   101401 aaccaacttg ttccgctttc tgattcttgg ctacaacacg ggaagattct acacgatgaa
   101461 caagttctgg atagcttttt actaatcctt ccagcatttc ttcgacaata ttgcttggat
   101521 cattcatgat ttttttcaat ttattcccat cctttctttc cggcattttg tgcttctgtt
   101581 aagatttgct gagtatcatc tgttataccg gcagtgatgg ctgctgcaaa agctccttcc
   101641 actaaaggcg catccaccag atgataacgt tgctgctgct cttcttccaa catgtctttt
   101701 gccagttccg agttcaatac cgcgctaccg atatccgcaa aaacaaaata actagctgca
   101761 tcgcttgatt cattgactgc ttctacgatt ttcatcgggt ctgatccgat ctcgccattt
   101821 attccgccga gagaaaaaat ttgcacctct tcggattttt gcatctgctc aatcatttct
   101881 ttaataccat ctgttacttt ttgactatga gaaataagca aaatactttt tttcacaaga
   101941 atcttccttt cttttacata gttgctaacg attggtttcg ctttcattaa tgaacaattc
   102001 aagtatataa taaatttcta attttgggaa aatatgtgta gtgcttcttg aagtttgtta
   102061 tactttaatt aaaagagagg agtgatcgaa tgattacaac aacaacgaac agtgtagagg
   102121 gaaaagccgt agtagcttat aaagggatcg tttttggtga ggtcattact gggatccatg
   102181 catttaaaga cttggaggcg gggttgcgaa atatctttgg cggccgctca aaaagctatg
   102241 aaaacgaact aatgggtgca agagaagaag cacttgccga aatggccgaa cgtgcaaaag
   102301 cattaggagc tgatgcgatc attggcgtaa aaatggacta tgaagtatta ggcagcgaca
   102361 atggcatgct gatggtcaca tgtagtggaa cagctgtctc cacgagataa gtaggggaca
   102421 tctgttttaa taactaaaga gagatgggac atgtagtggc actcaagaat tagatttttc
   102481 agtctaactt cgaggtactc taccttccca tcctctcttt tttatttctt tttgcggatg
   102541 attccgtaag ctgctgcgac taacacaccc gcccctgcta aggaataact gacagaagct
   102601 gttttttcat ttgtttttgg caaagtctga cttgttgatt tggatggctc tgtcgtttgc
   102661 tgaactgttt ctgtcgtgct tccagaggtc actgattttt ctcctgccga atgcaaaata
   102721 tcttttattc gttggaaact agctgctaag tcagcttttt ttgcttcaaa atcattagca
   102781 actgtttgtg cttcgctgat ctttccgtgg attgcttgac tggccgctgt gatatccgct
   102841 tgagtttgac ttagctttcc agaagctgtt tgagcaacct gatttaattg ctgattgaat
   102901 tcttttgctt gttggatctt cccgtcaaga tctgtttgga cagcttccgc ttttgctttc
   102961 gcttcggcaa gctttttctc aagttgtgca cggtcatttc ccactttatt tttaagatca
   103021 gctaaatctt gatcgattgc tgcttggtct tctttcaatt tgttttttgc agcttctaat
   103081 gcttcttcga gttcttttct tttattttcc aagtcttgca aatgatcgat ttggtcagaa
   103141 gaggtagaac tatttattga tgtatcttct gaagatgaaa tcgtttctcc tgaattatct
   103201 gtcggtacat tggaagtcat ttctgtttcc gaggcaccgt tttcagcacc agaagagctt
   103261 atggttgttg aaggttctgt ttgagcaggt tcagaagttt ccgcaaaagc tgtctgtccc
   103321 aataagaaaa tactggaaac agcaattggc cagattaacg gcttcattct ttttttcatc
   103381 acttttccca tccttactac tttttaacta atttcttatt ataagcaaaa atgtttggaa
   103441 gaaccataaa cacaacaggc tgtttgtcta aaaaacggtg catcttttat ttttttgtac
   103501 gttccgggct tttccatgtc ccgcttccat aacctaaaat cgttttgact gctggaatga
   103561 aagtcgtcac gatcgttatc gcgttcacta tccagaacaa aagcatatat agtggtgcga
   103621 aaagaaggta tttcaatttt cttcgtcgat catctacaat cagcgaagct agcaactgga
   103681 aaaatcctgc gaccatttca aagcagatga acacaaaact gaatgtaaaa gtaatataaa
   103741 tctgttcgta gtttccttga tatacataat gcccgattaa tccagcaaaa agaactacgg
   103801 aaatacaaaa gaatattgac cagacaatac tcaatgtttg atcaatgaag atgatcgttc
   103861 ttccaatatg tttaaaagga tggagcatca cttttttgaa attcgtcagc cagacttctg
   103921 ttccaccttt tgcccaacgt tttctgtgtc gatatagcat cttcaacgtc acaggtactt
   103981 ccatgaaaaa gataatctca ggagcaaaaa cagataacca gtcatttaac tgatgatccc
   104041 aagcaatact gatgtcttct gtcgctcgat cttgtctgaa tccgcccaca tcgatcaagg
   104101 cttcttttcg atacatcgta tttgctccac tgtacgcata aagaccaccg aaaacagctg
   104161 actgtgttcg tttaatgatg cccacgatac ttgagaattc aaccgtttga gattttgcaa
   104221 tcaatttggt acgattttgg acatccatat ttgcagtgac cgcagcaata tgtcttgcac
   104281 cagggcgaat gaaataattc acatacctaa tcagtgcatc tggctccggt accgtgtctg
   104341 catcattgct taaaatcaat ttcccttttg caaaggcaag tccgatatta aacgcgtggg
   104401 cttttccttt atttttttcg atccgaacca cacgaagatt agcgtatttt ttcatcagtc
   104461 tagctaatat ttctggtgtt tggtccgttg aaccatcgtc tgtcactaat acctcatagt
   104521 tgtgataatt caatttcgtc atcaaatact cgattgtata ttcgatcaca atttcttcat
   104581 tatgggctgg caccatgatc gtgatgaacg gttcgacact caagggaaca tctacccatt
   104641 ctttttgctt atgtttgtat aaaaacacat aacaccagac accaataaac catacaaatc
   104701 cgcctaaaat cggataagaa acgagaaaaa aatacataat agacaaacaa gtatctaaga
   104761 ataaattacc tgtatgggtg attgagatca tttcagttcc accccatttt ctttatacaa
   104821 atctgcaatg aatgtcgtat ctagattttt ctcttcggag acagaataaa aacggaccgt
   104881 ttctctctct tcttttgttc caaaacgttc cgtatacact tcttcaagta attcttgtct
   104941 ttttttcaat ttttcatctt catattcaaa agatttattt acttttttgt atagatttcg
   105001 attgttccac ctagtcaata caaatgaggt aatcaggaaa ctgaaaaaaa tcaatacaaa
   105061 aaagccgatt aagaaataca gcattttctt ttctgataaa aaagcgtaca aggaaaaatc
   105121 cttggctctt tctggtctcg ttaatgggaa aaagacccat ataaaaggaa gaacaacgat
   105181 catccatcct aaaagagcca ctaacgtttg ccaaatcttt aaccagtaat taccttttga
   105241 aaaatactta tctttcacca aaattgatgc aacttcttct cttgttactt ttttcatatc
   105301 ctcacctcac gtttttttgt tacgacgtag gagtttacca tacatttcat ttcttttcac
   105361 ataaagtgtt cctaaatttt tcctaagaaa aagaacaaaa catttctcat cagcaaatga
   105421 aaaatatttt gttcttttta tcagttgttc tttttatttt ttatctctta attatgttgc
   105481 tctttccaat acgacaatgc ttttcattcc tctagatatc gccgtgtaca tttgtctgcg
   105541 tcttctttgc tcatctccat cgttttcaaa tggatataag attacatgat caaattccag
   105601 tccttttgct agactcaaag gaatgatttg gcagttttct aatccatatg aatttttttt
   105661 aatcgattct tgtagcgttt gggtttcctc ttctgtttgg gtgataactg ccgctttttc
   105721 tccttttaga gaaaccaaaa tctcagctag tattttcaac aattcttcag aggatcgaaa
   105781 agagcggtat tcgggttctt ttccttgcgg tcggatcgat acgatgtcga tcttctcttg
   105841 atccacagca taggttttga aaagctctgt gattgctccg ctagaacggt aactatttct
   105901 aagatcatac cgatggatcg gcagatggta gtcgtcgaaa caacgcataa tatcagcaaa
   105961 agtagtggaa gaattaaaga ttgcctgatt ctcgtcacct actaaagtaa agtgagtttt
   106021 tggaaataat tcgatcaata gacctaattg tgccagggta taatcttgta cttcatcaat
   106081 caatagatag cgaaatgctg gtacatttac cttttcaaca agtaaatgac gaatagctaa
   106141 tataatgact gcttcatcaa cagtacgtgt gggttgccaa gcataagctg agccatatcg
   106201 tttttcataa attctttcaa acaactgatg ctcatccacc catgccattt cttcgatttg
   106261 tctggttatt tttcgatatt ttttttgtaa aagtttcctt gcataagcta caatactttg
   106321 ttccgaatca tcagaaatca atttaccgaa taattccaac tgcctatctt ctgtcaacga
   106381 gagtacctga ttctgcacag caggactttt tgcttgtttc aaaagatgat tcttccattc
   106441 gctcatcagt gcctttttcg ttgcttgaag cctatcgatc aatttaggat gagcaggaac
   106501 tttctcatat attttttcga tcgttttttt agaaaggact gtttttccat ttttagtaag
   106561 tccacggata aaattcggat gatctaaaaa caaaggatct gattgtttta gattatcgat
   106621 aaactttttg ctacgcaaac gttctgtctg ctccgataca ttttctcccg tgatacgttt
   106681 gaaataagcc tcttcacctt ctatttcctc tgctgaaagc tgtgaaacca gctgtatgat
   106741 ggttagattc agtggatttc tttcacctaa tgatggtagg acattcgaaa tatagtcgat
   106801 aaaccgatga ttaggtgata gaatcagcaa gtcatcggat gtcatcgtat ctcgatataa
   106861 atagagcaga tacgcaatac gctgcatgat agcagaggtt ttaccacttc ctgctacgcc
   106921 atttaccaag atattttgac ttttcacatc ccgaatgatt gtgttttgtt ccgattggat
   106981 cgtagcagtg atagccttca tttcattggt ctcatcttgg cctaagactt ctaataatac
   107041 gtcatcttga atagctacag acgtatcaaa aaacttgacc aaacgatctc tttccaaaag
   107101 aaattgtcgt ctttctttaa taaccgtatc gattttattt tgacgaaccg tataagaaga
   107161 tggaccaatc atgttattgt aaaaaagttc ggcaattggt gaacgccaat cataaacaag
   107221 attttcatct gcatcatctg tgaaatttgc tgtaccgata taaaaggatt cttttggctc
   107281 attatccaga aagtctacaa cgacttttcc aaagtaggga cttttcaata aacgttcgat
   107341 ctttgctagc tgattttctg cgtttttctg tttgatattc atctgatcga tttctctatt
   107401 tttcatttca atcatcgaaa aagtatccag gttatctaag taactgtcaa aattcaatcg
   107461 aagctcgcca gccatttctt tcaacgactg gtttccttct atttttgccg tatccatcga
   107521 ttcccgcagt tcgttttttt tatcaattag cttttgatac acgttcttca gatatgcttc
   107581 ttctaactgt ttttgtgtgt tgaccataca cattctcctc tttttttaaa gtggtggaac
   107641 cgattagttt acctctttta agagtcgaat gcaagctttt taacgagtat catttgttag
   107701 gatatatcag ttcttcaggt cggacagttt gatataaaga aaatgcacca tcaaggtttt
   107761 ttacgtggta gccagactgc ttcaagattc tttccgctag atagctacgt aatccgctat
   107821 gacagctgac gatatattct tgttggctgt ctaattcatt taatcggtcc cgaagttcat
   107881 tcaaagggat atgtttggct tccttgaatt tgcccttttc caattcttct gctgttcgca
   107941 catctaataa aatttttcct tttgctagtt ctgtcggcaa ttcatgccat tgtacggttt
   108001 cactaagccc ttctgcaatg ttcattgctg catatcctag catgtttact ggatctttgg
   108061 ctgagccaaa tggcggtgca tacgtcaatt ctaattccgg taaatcgaag atcgtcaaat
   108121 gccctttgat tgctgttgct aaaatatcga tccgtttatc cacacctttt gccccaacac
   108181 cttgtgcacc ataaatctcg ccagtctctg gatggaagat caacttcagt aaaatatctg
   108241 ttgcttctgg ataatagctt gcatgatctt ttcctgatac atgaatgact tcaaaagaca
   108301 gttcgttttc tttggctgtt ctttcactta aaccggtgga tgcggcagtc attccaaacg
   108361 ttcgtataat tgctgttcca ataccgcctt gatttcttcg agaaattccg gaaatcgtgt
   108421 ccgcaacttg tctaccttga cgattggctg gtgaagcaag agaaataagt gcatcttttc
   108481 cagtgatttg ctgttttaca acgatagcat cccccaccgc ataaatatca ggaatattcg
   108541 tttgataacg ttcgtctact aggatacccc cgcgtatgcc taattcgatt ccagcggtca
   108601 ctgctagctg gttatcagga cgaacaccaa tggataaaat aactaaatca gcagggatgg
   108661 tacgcccatc atccagtcgc aatcgtttcc cgtggtcttc aaatccagcg acagcatgag
   108721 aagtaatcac ttctactcct tgatgagaca attctttttc tataaaagct gccatttctt
   108781 catccagtgt tggaagaata tgtggtgctt gttcgatcac catgacttct aaacctcttc
   108841 tttttaggtt ttctgccatt tccaatccga tgaatcctgc accaacgatc acggcacgct
   108901 ttggctgttt ttctaatgca tgcatcactt tatcgatatc tggtacattt ctaatagaaa
   108961 aaacattgtc ggcttctgtt atccctggaa tcgatggaac aactggtttt gcaccaggag
   109021 ataaaaccaa tgcatcgtac tgttcaatgt gtttttgacc ctcatgtacg acttctaccg
   109081 ttttgttttc gggaaagatg gctgtcactt catgatttgg acgcacatct aaacaaaaac
   109141 gagcggataa tgattctggc gtttggacaa gaagattttc ccgttcactg atttctcccg
   109201 aaagataata aggcaagccg caatttgcaa aagaaacata cggtcctttt tcaaaaacaa
   109261 cgatttctgc atcttccatt aatcggcgaa gccgtgtagc agcagacatt ccacctgcta
   109321 cacctccgac aataacgatt ttcatcttat ttccctccta ctgttcgatc aaaccattga
   109381 ttcatgccac cacgtacatt cactacatca taaccagatt tctttaattc tttagctgct
   109441 tgtttactcc tcatccctga ttgacaaatc acatagacgg tcttttcttt gtctccatca
   109501 tatctgttta tactttgtaa tggaacattt ttagctcctt ttatatgccc gccccggtat
   109561 tctgcaggtg ttctaacatc aagtaacgct ggattttcca aaagcttttc ctttaattct
   109621 gggactgtta tcgattttat tgattgaaat agcaaattca ttttctgcac ctcatttaca
   109681 tttttataaa tacctcatgg ggtatattaa acaggagctt tattaatatg tcaaccagaa
   109741 tgactcttca tttttttcac tactttttat atttgcataa aataccgata aggggtatta
   109801 tctaattata aaaatagagg agaatgtgtt atggagattg ataataaaaa tatcctgaac
   109861 cgtttgaaac gtacagaggg acaaattcgt ggtatccaaa aaatgatcga agacgaaaaa
   109921 gaatgtatgg atgtcatcac tcaattaagc gctgttcgtt ctagtattga tcgcgtaatg
   109981 ggcatgatcg ttgcagataa tctgaaaaat tgctttgaga aacctgatag taatccagaa
   110041 gaacaagcgg ctaaactaga acaagcgatc aagatgatta ttaaaaagta aaggaatgat
   110101 ttcaatgaaa gtcgttttcc atattgatga attagaaaaa tggtcagaaa cagggaaaaa
   110161 cgtaaaaaac ctgataaaag cttctccaga aacgacgatt gtcgtatctg taaatggcat
   110221 cgcgattacc ggttatctag actctgccaa tgcagaattc ttagatttgc aaggagtcgt
   110281 ttttcacgct tgcgccaatg ctatgcgtgc taatcatatt tcagaaagtt ctttacctga
   110341 acaagtaatc gttgtaccag caggtgtcct tgatttagtt gaactgcaat cccaaggtta
   110401 tgcttatatc aagccttagt cagtagaggt tgcgacagaa gtgatcagct tcaagaaatt
   110461 tcggcttatt tttcgaagaa gctacttctg gaaaaccgtg aatcaaaggt tgtgaaaacg
   110521 ctgtcctgca tcaagtaata agaacagcca aacaaaaata gcttctcata tttttcgttt
   110581 ggttgggctt attaccgcag atgcaagctt ttgaacaccg tttaaggaag aggttgtgaa
   110641 atcagcggtt tgacctaagt attagagaaa aaaacgggaa aatagctcct catattttgc
   110701 cgttttttga gctaataccg aaggtcagct gattgaacac cgtttaagga agagattgtg
   110761 aaaaagtcgc ttagtttcga gtattaagaa aaattttgta aaaatggatt tctacatttt
   110821 tgcataaatt tggcttaata ccgagaaact ggcttttgaa taccgtttaa ggaagaggtt
   110881 gtaaaatcag cggtttgacc tgagtattag agaaacaaac ggaaaaatag ctgctcatat
   110941 tttgccgttt tttgagctaa taccgaaggt cagctgattg aacaccgttt accaagaggt
   111001 tgtgagccta ccatttaact ccgaatcaca agaaataatt tcaaaaacaa cttctcctgt
   111061 ttttggttcg gttggcttat tatcgagaag tagctactgg gagtctattt atcaaaaaaa
   111121 ggaatgcgac ataggtcaca cccctttttt attttctttg aaacatcttt cggtactcga
   111181 cagcatacaa gacaaaagat tgtaaaagac cgtaagtgat gacggcaaaa atgactctca
   111241 cccacagcgt tggtaattct gggaaaagca gcaaaaggat catgccaaca tagatgacag
   111301 cagtcgctac tttgccatac cacttcgctc cacttaattt gatattttta gatagcccga
   111361 ttaatccagc tacaaacata aagccttctt ttatcaagaa tagaccaaac aacagccaaa
   111421 gccacggtcg ataccatgcc atagacaaaa tcagaaaaag ttgtgtcaat ttatctgcaa
   111481 acggatcaag caccttccct aagtctgtta cctgattata tctccgagca atgaccccgt
   111541 ctagataatc agacaaacct gagacaacaa tgaccgctcc tgctatataa aatgactgtc
   111601 tcagcacaaa ataaagataa atcggcagca aaaaaatacg gaatatcgat aaaagattcg
   111661 gaatcgtttg tatttcttta cgccagtctg tgcttaattt cattttatcg ccctacctcc
   111721 tcagcactct tttcttttta ttttagctta cacggggaat aaaaccaatg atttcactgt
   111781 ttttattttt ctttacagac actgatatta tgagctaatt tgagataatc acttgctgtt
   111841 ttcatcgttt actcttcttt cttcctgtcg tttgcgcatt tcttttacta gtactttatg
   111901 agcttttttt gatcctcgct ctaggtcacg ctgccgttta cgtgttttat aatcgataaa
   111961 cagactgtct aaatcgtaac ctgtcgggta cagatcttct gctgaacgca ccagacgaac
   112021 acgctgacga ggcacgtgga ttattttttt gtctaaatat acatcaatcg tatcttcacc
   112081 tatatcttca taaactaacg cttctttttg gtattcattg acaaatatcc gatcaccttt
   112141 tgcaaagagc tgacgttctt ttttattctc cttcctattt gtaactgctg tcttaggaag
   112201 aaattctttt ttctgtgtcc gataggcttt ttccgccaag taacgctttg cttgatggat
   112261 caatttcatc gacatatcca ttttatgagc aatccacaaa gcttggcttt ctcctgtttc
   112321 ttccaacccg caactgatat ttaggacgaa gtgcttcccg atcgaaagcc atagcagccg
   112381 gcacaaaatc ttcatgatct ccggcgaatt tcttgatttc tccataatgg gtcgtggcaa
   112441 tgatcaatgc cccttgctca tacatagatt ccatgattgc gatcgctagt gcagcccctt
   112501 catttggctc tgttccactg ccaatctcat ctaaaagtac caacgtattc ctttttatct
   112561 ttttcaaaat agcagcgatg ttttgcatat gaccagaaaa tgtactcaac gcattttcta
   112621 aattttggtg gtcaccgaca tcgacgaaaa tctcatcaaa gacagcaagc tctgtccctt
   112681 cttttgccgg aacttgcata ccgaacatcg ccatcaaagt caataaaccg actgtcttca
   112741 acacgactgt tttgcctccg gcatttgctc cggtgataat caagcctcga tagtctttac
   112801 cgatttcaac atccaatggt accgcatgct caggtaaaaa tggatgtctg ccttgcttga
   112861 taatgatatg ttccgattta ttgattctag gtgtgcttcc attgatttct cggctaaatt
   112921 ttgcccgagc aaagatgata tctaacaccg tgatcgtttc gatcaataaa tcgatcactt
   112981 cttcgttttc tgcgatagca ccagtcaatg ccgccaggac ttgatattct tcactgattt
   113041 cttcagcttt taacaactga tagtgttcat tcaatttaga aatcacagtt ggttcaataa
   113101 aaaccgtcgt tcttttattt gattcatcga taatcgttcc atctatttta tttttatagc
   113161 tggctttgat aggaatcgta tagtattcgc ctttttgaac aatcattgct tcttggatca
   113221 tttctttgtt tttcggatga cgcaagaatt tcagtaattt tgactggatt tctttttcga
   113281 ttagttgtaa ttgtttgcgt actttacgca aattacgtga cgcgtcgtca ctgactttat
   113341 tattttttat tttctggtca atcaactctt ctacatttat caaatcagga agatgtttgc
   113401 tataagcaaa caacaagggt gtctggtatt gattcttatc aaaaaacttt gtgatcatcc
   113461 gactgcttct aagaaaatcc gcatattcga tcaaatcggt tggctgcaga atcaaccctt
   113521 ttttgacttg ttctgtcagt gcatcgatcc tcggcaaccc cataaatgga acatgctgac
   113581 tgctttctaa gatcaagcgt gcttctcttg tttcttcttg acgatccaag acagtttgta
   113641 ggtttgtcga gaccgtcata tcgctgattc gttttttgct atagtttcca attgctcttg
   113701 cttggatttc ctttttgatc cgatcaaatt gtaattgact aatcatttcg ttgtccatat
   113761 tctctccttt tcttgaagag atacctgtcc caaaataaat aagggcctag agataaataa
   113821 aaggatagaa cacagcttaa aaaagtcatg tcctatcctt attagaatac aaagatattg
   113881 ttttcctgac aggtaccgtt tcataagcac accaaataaa ctttgtttat tggctattcg
   113941 acttactgat tagataccag ctacactcac aaaacatacc ccattcttct aggtcttatt
   114001 tattttccac ttaactatag caagacacat tttggttgtc aaactttagt atgttttata
   114061 gatttacacc attaatgaat agacacctac cgcgataatt gctccgatca ttggacctgc
   114121 gattggtacc catgaatatg cccaatctga agttccttta ttagctattg gcaataccgc
   114181 atgtgctaat cgaggaccaa agtcccgagc agggttgatt gcatatcctg ttggccctcc
   114241 taatgaaaga ccgatggcta agatcaatcc acctacagcg aatacgttcg ttccaggtgc
   114301 aaattcgttt tgtccaaaag ctagcaaccc aagaactaat acaaatgtac caattaattc
   114361 tgtgatcaca tttgctggat aattccgtat agcaggacct gttgcaaacg ttcctaaaat
   114421 cgcgctttca tctttcgttg cattccaatg tggcaaataa gaaagccaaa caagaatggc
   114481 ccctgcaaaa gctcctaaaa cttgcgcaat gatgaaagga acgacaagat tccaactaat
   114541 tgcccctgtc atcgccatag ctagagagac tgcaggattc aaatgagctg ggcccatgaa
   114601 tccagaaata tagacagcca ttgttacagc gagtccccaa ccaaatgcga tgacaatcca
   114661 gccagaagcc tgtgctttac ttttgtttaa attcacagcc gcacacacac catctccaag
   114721 caaaactagg atcagtgtcc caataaactc ccccatgatt tgagtcatat cactgttcat
   114781 ttatttctcc ccctttagtt cccgcagatc tgattctgca atcaatgctt ctaaacgttt
   114841 agtctgttgc gccttctcct cttctgtcca ttcaaaatat ccagcaattg catcgatcac
   114901 aggttgcttg atctcatcaa gctgatctcg ttcaaacaac agatgatttg tacgacgaat
   114961 gagataatcg cctggggcca aaaccatttc ttcttctaaa ccataacgta accgagctga
   115021 ctcagcgaga ctcaaaccag gataaggtgc catttctttt gctaattcaa agatacgtcg
   115081 ggcattagtc ccgtaaaaat cagcgatata agtagcatct tcttcctcta aaccggctgc
   115141 tactccttct tttgctaatt ctgtcactgt ttcttctaat ttagttggat cgaagtttcc
   115201 acctgaaatc tgatattttt tagagtcgat ttctttcgtc tctattccgt attcttcttt
   115261 taataattgg cgtatcaatc gcaaagctcc ttctgccatc ttacggtaat cggtgatttt
   115321 cccaccagat aaagtcagca aaccatctgg ttctctttct aaagaactac ctctggaaat
   115381 cgtagaaggt gctttttcat cacggctgtt ttccaaatgg ttcaacacgt cttctacttc
   115441 agcacgagaa actttgtttt ccttatattc acttactgta tcgacaactt tattgaagct
   115501 cttgtctgaa atcgatccat tatctccacc attgtaatca gaaccagaat taccaatcaa
   115561 cagtggacga agtcctgccc agcttgcttc gatatcattc aatgtgatat ttgcttctgg
   115621 atagcgatga ttgatcacat ccaatagata atctacatct tcttgtgtga ctttcggatc
   115681 cgtaaaatct ccttggtaat ccgtatctgt cgtaccaaag taagtcttgt tttctcttgg
   115741 aatagcaaaa accatccgcc catcttgctt tcctgtatcg aagtatgtgg gttgcggtac
   115801 aggcagtttt ttcgcatcta caactaaatg gatcccttta gttggacgca ttttaggaga
   115861 gactggacgc gtaaaattca agtttcgtac tttatctacc caaggaccac tcgtattgat
   115921 cactaatttt gctttgattt cgatcacttc atctgtcagc aggtcacgag ctttgacgcc
   115981 aacgatttga tcgccatcat ataaaaagcc aaccgctttc attttactta ctagataagc
   116041 cccatcttcg gcagcctttt tgatattatc aatcactaaa cgggcatcat tgttgcggaa
   116101 atctagatag acacccgcgc cttttagccc ttcttttttc aaaaacggtt ctctttccaa
   116161 tacttcttct ggtgtcagcg tataattctc atatttggtt cctgtcacat ttgccagttt
   116221 gtcataaagg tccattgcta ctttgaccga gaacatattg aaggttgttg ctccttcgcc
   116281 ctcatagatt ggcaaaagca ttggatctgg ttttgggatg tgtggggcaa tactttgtac
   116341 gactgcacgt tcaccaactg tgtcagctac tacttccaca tcaaatgtct tcagataacg
   116401 aataccgcca tgaacaagtt tggtcgagcg agaggaagtc ccttctgcaa aatcctgcat
   116461 ttcgatcaat cctgttttga ttcctgatgc tgctgactgg actgccacac cggcaccagt
   116521 gattccgcca ccgatgatca acagatccaa ttcttcttgc tgcatttttt gaatgctatc
   116581 ttgtcttgtc ttgtttgaaa acatatggat ttcctcctta ttcaaatgct tgggtagctt
   116641 ttactgcttt tttccaaccg ttgtaaagtt tttctcggcg ctcttcctcc atttgaactt
   116701 caaatagctt gccagcttca taaaattcgc ggatctcgtc tgtatctttc caataaccga
   116761 cagctaatcc tgctaaaaat gctgccccta gcgccgttgt ttccaagttt tctgctcgtt
   116821 ggatcggtac attcaagata tctgtttgga attgcatcag atattcattg tttgctgcac
   116881 cgccatctac tttcaataca ggaatcttga ttccagtgtc atcttgcatc gtatcgatga
   116941 tatctctcac ttgataagca atcgactgta aagtagcttt aatgatatct tcttttgtcg
   117001 taccacgtgt caagccaaac atagcccctc gtgctgcctg atcccaataa ggagcaccta
   117061 gcccaacgaa tgcaggaaca acataaacct catcttcgct tgtagagcgt ttcgctgcgt
   117121 cttctgaatc gctagctttt tgcaacattt gaagtccatc tctcagccat tgaatcgaag
   117181 aaccagccac aaaaatactt ccttctaaag catagtaaac ctttccattt atgccgtaac
   117241 caattgtcgt caataaatta tttttggata attgcggttt ttcaccggta ttcatgacaa
   117301 taaatgaacc tgtaccataa gtattcttga ccatgcctgg ttcgaatgcc atttgtccga
   117361 ataatgcggc ttgctggtct cctgccatcc ctgaaattgg tgcttcgctt ccataaaaat
   117421 gataaccttg cgtataacca taaacttctg agttagaagt gacttttggt aacatcactc
   117481 gaggaatatt tagtaaatct aaaatctcct gatcccaatc tagctgatgg atattgaaca
   117541 acatcgtccg actggcattc gagtaatcag taacatgtgc ttgtccatcg gtcagtttcc
   117601 atactaacca agaatcgatc gttccaaaca tcaattcgcc tttttcagct cgttcttgcg
   117661 cgccttctac atgatcaaga atccagcgta tcttcgttgc tgagaaatag gcatcgatca
   117721 ctaaccctgt tttttcgtgg aaaaattctt gatagccttc attttttaag ttatctgcaa
   117781 ttccagctga ctgtctggat tgccaaacaa ctgcatgata gattggacgt cctgtatctt
   117841 tttcccatat tactgttgtt tcacgctggt tcgttatgcc aatcccagca atctgatttg
   117901 gtttgatccc tgattcgatg aacgctccgg caataactga ctgtacagaa ttccagattt
   117961 catttgcatc atgttccacc caactttctt gcgggaaata ttgcgtgaac tctttttgag
   118021 aactgccgat gtgtcttcct ttcttgtcaa agataattgc tcgtgagcta gttgtacctt
   118081 ggtcaatcgc catgatatac gttgattctg tcattgtgat tccctccatt atatgcaaac
   118141 gctttcttta actactctta tcatactact gttttaaaaa aagaaactgt caaaatttta
   118201 ttcttttttt ctttttttga cagtttttta ttatgaagct attttttaat caattctttt
   118261 cttttttcag cgtctctatt cttcttttca atcgaataat gtcgtaaggt gacgcaaatt
   118321 ctgacagata atattcacac tgttttttgt ttctctggca aaatgtgatc accaaatcat
   118381 attctttacc ttcttcataa cttccaatct caataccgcc gattcccctc agttctctga
   118441 tcagatattg ttgaaaagca atacgataaa tcggcagact ttctaaatcg attccaatca
   118501 ctactggttt tgcaatataa aaatcgatca tcaaaagaac attggcatac tggatcatca
   118561 ggtaactaag ctcactatct tcagctcttt tcctcggcaa ttgctgcacc gctgtttcct
   118621 gtaatttcgc cagtaactgt gttaaggaat gcccgagcat tttctgctgc tgttccaaaa
   118681 gccgatcacg ctcatagact tcgatctttc caacaaagaa aaaccattca ttgttgatct
   118741 gggaaatttg gtagcctact gccttttctt ctttgatttt caaacgacga ggacgataat
   118801 gccataacat cgtttcccga atgtaagtat ctaaaacagc ggttggtaac tttttgctcc
   118861 gtgtcaaatc atactgataa aatatttctt cgtctactat cgaaaaagaa acaaaaaagc
   118921 tgtaaaacat cattgtttcg tatacattca gttctgctgc tgttcgacta agatgcatca
   118981 cgatgattgg atcgattgct tgataaagcc ggtccgactg atagagtaat ttcttttctt
   119041 tcaaagttgc gtacgtactt ttttcattca atagtctttt tttcgtaatc ccgagccagc
   119101 aagcaatctg tgcttctgct gatgccgtaa acgttgtttc taatacacgg tccaatccta
   119161 gaatgaacgg tcttttttct ggtgtatttt gcaaaaaaag cggtcgctga tcttccggga
   119221 tatattggaa tagttcataa taaaaatatc gtatctgtag ctcttctccg tataattgac
   119281 cgtttttgat ttgtaatcca aattcctcta agagctggtt caattctttg atctttcgaa
   119341 aaacagaaga ctcactgata ttaaacgctg tcgctaatcg aacgatggat acttgctgat
   119401 gttctaataa atagacgagc atcttaaact tcaagctttc ctgcaataaa aacaatagaa
   119461 ttttttccaa acttacatct tcgtccaaca caagcagcgc ctgatactca tttcgctgta
   119521 cttctacttt tttttccatc attcggccaa tcaattcaat atcttccaaa tattgatcaa
   119581 acgaggcttt tgacagttgg acatgctctc tcaaaccatt gatagaggct gttccccctt
   119641 gcagaacaag gtttcgcaaa atcaggatct gtaactgctc ttttctttct aataatgctt
   119701 caatcttcat aggcagtatt cgccaccttt gaccacacca tatctggcac acggtattct
   119761 ggctggaaaa atagctcatg ttcttctaac tgttcaaacg tccatccttc ttctactgca
   119821 attgtcagtt ggtcaagaag gtggaacatc tcttttttgc tttggagctg tgctccaaga
   119881 atcttttttt cagaatcaaa tagaaatttg agtttaactt tgctttgatt tattgctgta
   119941 agcttgtagt ctacgtatcc tgtttcaatt ttttggggat aaaaaatgct ctcttcttct
   120001 gtcaaaccta cgcttcctaa gaaatagcca aaccactgat tgccgactgg acgataggtt
   120061 ccctgatcct ttgtctgtga gccactaatt gtcttgctga catttcgtgc tgtacggaca
   120121 gcgttattta ctagagaaac atacattttt tcatttgttg gacgaaaagt tacttggatc
   120181 gcatcgccaa tcgcataaac gtctttttga gacgtttgca agtagtcatc tacccagatc
   120241 gttccatcat cattcaatgt taattgttct tcccacatct gattgtcggg acgagaatga
   120301 ttagccagca aaacaagatc atagttctcc tttctttttt ccgtctctac aatagcggtt
   120361 tcattttcgg tcaaagacac aacttgttct tctaaaaaaa gtgaaagccc ttgatttttc
   120421 atttccttta ctaacggttc tgtcatttca ggatctagat aacgaaaaag aattgacttt
   120481 cggctttcgt aaagatggat ttgttttttt cttgatgcca acccttcagc tatttcgatt
   120541 cctgcttgtc ctgcaccaat aattgcaatt ttctttgcat tcatgatctt ttgctgaaga
   120601 gccgttacgt tttgtatctt tttaactggg tgaataagcg ttgattctgc agaaatattt
   120661 cgaaactttt gatttgaacc agtcgctaga atcaaacgat caaaatccaa tttttttcct
   120721 cctgctaaaa cgactttttt ttctttcaat cctattactg tcttttctgt gtaaacatgg
   120781 attcgatagc ggtcagtcag ttcttctttc gtgatccaag aaagttgttt ttcactggta
   120841 acctttcctt ttaatatcaa attgaacccg ctgggaatcc atcctaactt cgattgcttt
   120901 tcaatcaaat atatttcact tgttggcatc aattggcgaa gataaatagc cgcatgaatc
   120961 cctgcaaacg acccgccgac aattacaatg ttcatctgca ttcctctttc ttataaggtg
   121021 ttctactgct aacttctcaa tcagaaaaca cagtattcat aactcgcttt caaccttatg
   121081 atacatagcg atgcagcaga atcaaccctc tccatcatac cgtgttctag gtctgcttct
   121141 caataatgta ctagtggacc taattgaaga gtatcatttc tgaagagatg tttcaaaaaa
   121201 tgtactctta taaaagaaaa aaactcgcct tttacgtacc tctgtccaaa taggaaacag
   121261 aaaagaacga aaagacgagt tttagcgtgt gtaatgtaat agttagaata gacacatcat
   121321 ttatttttaa ttctttaatg cttcaacaac tgcttcgcct aattgatgag cagattgagg
   121381 attttgccct gtaagaagcc gcccatcaat ttgaaccact tctgaaaaag ctgctccaga
   121441 ctgatagttt gctccttttt ctttcaaagc atcttctgct aagaatggta cttcattcgt
   121501 tgtaccattt gcttcctctt cttcattact gaacccagtc actgtacgtc cagctaaaat
   121561 agattttcca gactcatctg taactggcaa caatcctaca acaccgtgac aaacagctga
   121621 gaccagccct tcatttcgat agatttgtga agcgactttc ccaagatcta ttgcttctgg
   121681 aaaatcccac attgttccgt ggccaccagc ataataaacc gctgcataat catttgcatc
   121741 cacatcatca ggacgtaagg tatttcccaa ggcccgattt ctgaaatctt catcttcata
   121801 ataggcccaa tcgatttcat ccatattcaa aacactttgc ggttctaaag gtacatatcc
   121861 gcctttagga ctgacaaaat ctgcatcgat cccatttttt actaatacat cataaaaatg
   121921 agtcagttca cttaaccaca aacctgtagg acgctcgatc ttttcgtact tttctacatt
   121981 tgttaatacg atcaatactt tcattttccc atcctctttc tataaaaatt gcgttattga
   122041 taacgtgctt tcaagaaatt atataatggg cttggcaaat aaagctcttt atatgcttct
   122101 tcaaaaggtt tcgttacaaa ttcatcctca cggttttcca ataatttctc tgcccagtca
   122161 ggatcgacga tcatttgctg tccaattgct gcaagttctg catatttcaa tacctgctct
   122221 acatcttcgc gattgcggat cccaccgaca ccaactaaag ggatctttcc ttgaatcgtg
   122281 ttatggacca cttcaagaat cgatttatcg ttgtatttat cagaacgagc tattcgatca
   122341 tacatattta atgaaacatg cagataatct agttttgact cacgtaatcg ttcaagaagc
   122401 cagatcgtgt cttcaaaacg gatacctggt gtttcatatt cttctggtga gaaacgatac
   122461 cctacgatga atggtttttt agcatattgt tcaaccgctg agaaaaccgt tgttaataat
   122521 tcttcaataa aacgataacg attttccaag ctaccgcccc attgatcctc tcgtctattc
   122581 gaatgcggag agaaaaattg ttggatcaaa tacgtatttg ctccatgcaa ctcgattcca
   122641 tcaaatcctg attcaatcgc tctacgtgtg gctttgccaa atgcttggat tgtttcaacg
   122701 atttcttctt cactcattgc tcgtggtgtt tccgcatcag gacgttttgc tgcaactgca
   122761 cttgcagata caggctgttc tccagataaa gttgctcgac ttgtcattcg tccaccgtgg
   122821 aaaatctgaa taatcgcttt tgcgccttct ccttggattg ctttcgctag ctcacttaat
   122881 cgaggaatca tttcatcatg agcgatgctg agttcacctg gccagccttt tccgatatct
   122941 tggacatttg cagcaccagt aataacagca ccaagacctt tagaacgttg tttataataa
   123001 gtgatctcat cttcggtgat cactccattg aaaaagctga gttgtgtcgt cataggcgac
   123061 agcatcaatc ggttcttcaa ttgaactcct gaaggtaaag taattgattg atcaaattgt
   123121 gacattgtca ttcctcccat aattcgctct gattaaccta tcgagaatca tctatcatta
   123181 aaccactcga ttagttgtac atgcaactaa tttgcttaaa aaattttatt ttttttgtaa
   123241 cttatctgtt gcatcattca ttgtctgggc taattcttta cttgcttcat ttcccaaaac
   123301 tgctttgtat gactgatgaa gttcttccca gctaccatcg acttccttag caaattggcg
   123361 tccttgttct gtaagataaa ctaatgacaa gcgaccttcg ctaactgttt tgacgtatcc
   123421 tttatattct aatttttcaa caaaacgagc aatcgttgat ggggcggaat agagcatttg
   123481 tgcaatatct ttttgtggta ttccatcttt ttcttttaat atcaataaaa taaaaccata
   123541 agttggtgcc agacctgtcc ttctaaacgc ttcatcagct aatttattca acatgcgatc
   123601 tagctttttc acgctaaaga aaagacattc atctaacgct ttttcaattg gcttttccat
   123661 ttcatcccct ccattggcgt acatatcata gtatgatttt tattttttgt caaaaaacac
   123721 ggaataatgt ccgcctcctc tgtctagatt tgaaaaaaag aagtagccat cttcaaagaa
   123781 tttcggcttg ttttcgacaa aactccttct ggaacaccgt gaatcagagg ttgtgaaaaa
   123841 gtcgtttagt tttgagtatg aagaaaaatt ttgtgaaaat ggctttccac atttttgcat
   123901 aaatttggct taataccgaa aaactggctt ttgaacaccg tttatatcag aggttgtgaa
   123961 aaagccgtcc tgcatcaagt aataagaaca gccaaacaaa aatagttcct catattttgt
   124021 cgttttttga gctaatgccg atggtcagct gattgtacac cgtttattga gaggtcgtga
   124081 gcctgccgtt gaactccgag tcacaaggag caatttcaaa aaacagcttc tcatgtttta
   124141 tgactatggt gacttgtgat cgaggagttg gcaggagaat actgtttatt cgtaaagaag
   124201 gggctgtgac aagacttttg tcacagtccc ttatttcctt ttattatagg atttcgccat
   124261 ttgattggat gacttgtctg taccaatcaa atgatttttt ctttaaccgt ttctttgtgc
   124321 cattcccttc gtcatcttga tcaacataga tatatccata acgttttgac atttgtgaag
   124381 tagaagcgct gacgatatca atgcagcccc acgacgtata accaaataaa tctactccat
   124441 ctttgatagc ttccttcatc tgctcaatat gctgcttcaa atagtcaatg cggtaatcgt
   124501 cttgaacggt tccatcttct tctactttgt ctatagctcc gagtccgttt tcagctatga
   124561 acagtggttt ttgataccta tcatataatt gattcaaagc aattctcaaa cccttaggat
   124621 caatctgcca gccccattca cttgatggaa gatacggatt tttaattcct ccagttatta
   124681 agtttccttg gaccccttcc caattttctg gatgagcact gactgcacta gacatgtagt
   124741 agctaaaaga aacaaaatca acagggtagg ctgctaagat ttcttcatca cctacttcta
   124801 tttttaagtt gacacctttt tcttcaaaca ttcgttgcgt atacgctgga taatatcctc
   124861 ttgcttgaac atcactaaag aacaaagaag ttctttgctg ctcaattgtt ttttgaatat
   124921 catccggatc acaagaatac ggaacaagaa gctgatagct gatcatacaa ccgacttgtg
   124981 aacctttgat aatttcatga caagcttttg tagctaaagc acttgctata aactgatggt
   125041 gtgcaccttg gtatttcgct tgttccaaat ggggatggtt ttcttcaatt actcctacgc
   125101 taacaaaagg gtgatgtttt acacagttga tctcattgaa agtcatccaa tattttactt
   125161 tatttttata gcgtttgaat actgtttcag cgaaacgaac gtaaaactga ataagctttc
   125221 gattaggcca tccaccatat tctgtaacca aatataacgg catttcataa tgggaaagag
   125281 aaacgactgg ctcaatccca tattttagac attcgtcaaa cacttgatca taaaaaaata
   125341 atcccgcttc attgggtgtt tcttcatcac catgaggaaa aattcttgtc catgcgatag
   125401 acatccgata gcatttaaaa cccatttcag caaataaacg gatgtcttct ttaaagtgat
   125461 gatagaaatc atttccgtgt cttttaggat aataatactt gctgttggga tcctgcgccg
   125521 cttttacttg ctgatgcgtc atcatatgcc attgatctgt ccatttttct ttaggtaaat
   125581 cgctgtcgaa tgtatacaca tcagacacag ataatccttt ttcatctaca tcccatgcac
   125641 cttcacattg attggccgct gtcgctccgc cccataaaaa tccttctgga aattttttca
   125701 tatcgatccc cctaaacttg ctagttttct tgtttgatta tttttcttat gactagtaat
   125761 gatatttttg aatctactac tatttgtaac aataaccatt gtggtcggat catatccctc
   125821 tttgattaat tcttgcaaat ctacttccat caataaatcg cctttacgta ctttttttcc
   125881 atcagatact gcactttgaa agtatttgcc atttaaattc actgtatcaa taccgatatg
   125941 gatcagtatc tctgctcctt cttcactgac taccccaatt gcatgtttcg ttggaaaaac
   126001 tgttgaaact tccccgttta cagaactgta gatttttccg tccgttggaa tgatcgcaaa
   126061 cccttctcct aaagatccac tagcaaatgt tggatcgttt acttcagata aatcaattat
   126121 ttcacctgct gcaggagtac ttaacactat atcctttgag gattcttctt cgatttcatc
   126181 cttgtagccg aaaagaaaag ttagcataca ggaactgatc atcgctaaga aataactagc
   126241 aactagccaa acaaatcctt caccaatata aatcgggaaa gacaaaatac ttcttgtagc
   126301 aactgccaaa gcaccggctc ctgcggcacc agctactcca ccaaatatag ctccacatat
   126361 acaagcaatg taaaatggtc gtttatattt aagagtcaca ccataaacag caggttcagt
   126421 gattccaaat aatgctgtga taaatgcaga taaagataaa ctttttactt tcttattttt
   126481 cgttttcaaa aataccccaa gtactgctcc tgcttgcgca gctacggcag tcatacatgc
   126541 tggacctagc gtatcacgac cgtagaaaga aagattgttg gtcattactg gtacaagtcc
   126601 ccaatgtaac ccaaaaatca ctaacacttg ccaaaatccg ccgataacag caccagataa
   126661 aacagggcta aagttataaa cagctaaata tccagctgca atcagctgac ttgcataatc
   126721 tgcaattgga cctacaacta ataaaataat tgggaccatc acgatgatac aaatgaatgg
   126781 tgtcaataaa tttcgaatac tttcgtgcaa gcttttgcga atcttaggct caatataaga
   126841 aagaacccat acagctaaaa ttgctggaat aaccgtactt gtataccttg ctagaatcac
   126901 gggcatccct agaaatcgca aggttatgct atcactatat gcactgacaa tcgtaggata
   126961 aacgagagct gctgcaataa ccatagcgat gaaacgatct gtattgaact tttttgcagc
   127021 agtatatgcc aaaaatatag gcaagaaata gaaaaatgca tcagctgctg cattcaaaat
   127081 gatataagtt cctgattcag tagttaataa attcaaactc gtacataagg cgagtactcc
   127141 tttgatcaaa ccacttcctg ccaagacgcc taaagtcggg gcaaaaacag cggcgatcat
   127201 gtctataaaa gagtttaaaa tgcctttttt ctcagttcct ctctttccac tagatgcatc
   127261 atcttctagt ttcatttgtt tggataatac gtcatacact tcatttactg catttcctac
   127321 tacgacttga aacattcctc cagcttcgac tacagtgatc acaccttcta gttgctctac
   127381 cttctcctta tctgccttct tattatcttt tagggtaaag cgtaaccttg ttgcacaatg
   127441 gtaaacattg ctgacatttt cttcgcctcc gacaaatcgg acaatatctt tcgctaattg
   127501 tgaatagtcc atttttactt cccccttgtt aattaatgcc gtagcaatcc ttcttacaag
   127561 ataagtatag ttcttagaaa acggtttctc cattcaatta gtaccccttc taatagcgaa
   127621 cgaaactgta caatagtgtg tatggtttac ttagccgagc aaatcactca ctgcttgaaa
   127681 gaaaacaagt atatcgtttc tcttatagtc aaaggagaca aaaaaaacac gcttgatctt
   127741 cctttgctga tgtataagtg gtatctcaag ctgatactct gtgatttttg tttctacttg
   127801 gcttttgata agacagcaca acaaagtctc ggcatttaac ggaagcataa ctaggtcaga
   127861 actaggagag attagttgct gaatggaatc tatcttttta tggattttta tttgattttc
   127921 ttctttgtag taatgatcaa gcagttttgt tttctttttt tcttcaacta tggtcagctt
   127981 ttcacgcaaa atctgataaa tctcccaaga ttcaaactca tctagaacac taggtagata
   128041 aatcaaatca tcccactcaa aaataagctc ttgctcagta gtcaaaattg catcatattc
   128101 cgttattttg tttgattgat ttttgaaaag atacactggt tctatccggc attctttgat
   128161 ccacatgttc atactttgtt gaatctgttt ttttagtgta ttcaaaatac taattggctg
   128221 gttactaaca atcagtatct ccccttgttt tcgaaaagga ttcaacgctt cggcaagata
   128281 caaaacaaaa taagcgcttt cagctaaatt gggacgtaat tgaaaatgta ttgggaagaa
   128341 acgccgaatt aaataaattt ctaaaggata acgggagatg atcttttgta caaaatgatt
   128401 catggtatta tgtccggcat ccatcctcgt tttcatttgt ttgatatggg ttagcaaaaa
   128461 ttctgtttca tggaacaata acgaaacagg aagatctaaa aaacgaataa tcgtttgctc
   128521 aaatgctctt agattcttct ctatttcttt gtttttttca tcattaatca tcaaataatt
   128581 taactctaat agtcgatttt caattgcttg tttttcttga ttggaaaaag aatagggtag
   128641 ttctgatgat aacttttttg tgagggtctc taccatcgga ataaataatg tatacctgtt
   128701 tgttttttct aaaagttctt ctcttcgaag aatggtcaaa acgagatacc gagaaaatcg
   128761 tatgaagtcc tctcctgaaa caatataatt atatgatata agaacctctt ttaatgtctt
   128821 ttggacagtc ggcatgatat tggaaaaaat tgtactgatt tgttgaggca accttgcgtg
   128881 ttggatcacc gtttctgttc caacaagaga taagaaaatt ctttttgaat tttcttcagc
   128941 aatgattttt agtccttttg tcgacgaaac ttccagttct aatttaggat tgcgctcgat
   129001 ccaacgcaaa atcgttttta tttgtaatga tacggctgtt tttgaaagaa agaaaatgtc
   129061 tgctatcttt tgcatactga catacccttt ttgaaacaat aagtacgtca caatagttga
   129121 agctcggaaa tccatgctgg aatagatttt atgtttcgtc acctcttgta tgatttgctg
   129181 tttagtttca gattcaattg attctaaaaa ataacctgaa cgtttatttg actggataat
   129241 gattttcttc tcgtagatag caagcatatt tttgatttca gtttggatcg ttttcttgtt
   129301 ggtacctaaa gcttcagcta attcttcgct tgttatccaa tgattcttat ttcttaatac
   129361 tacaagaatt tggagttgtc gtttatttaa gtccatttgc ttacacctcc tctttgttat
   129421 aaacatacag gaaaaacctc tcaaatgaca atagtcactt gcagaggttt aaaaatcatt
   129481 tgaagaaaga tctatattca aggtttttac cattagactg gataatttgt ttataatatt
   129541 caaaactatc ttttttcaat ctcctaaagc ttccgctccc atcattttgt ctatccacat
   129601 aaataaagcc atatcgcttc ctcatttccc ctgttcctgc cgatacgata tcgattggtc
   129661 cccaccataa gtaaccaatg atttggcaac catcttttat tgcctcagca atttcctgaa
   129721 gatgtatttt tagatactca caacgttttg gatcgtggat tcgattcaat tcatctggtg
   129781 cttcatctag tccaatgcca ttttcaacta tgaataatgg taattcataa cggtctgtca
   129841 attcattcat gacataacga aaccctagag gatcaattgg ccaactccaa ggttcgggag
   129901 atttttcctt caaaaaggga ttatcgaaac catttgctcc gccagtatct acgcgcattt
   129961 ctgcttcttt tttatagaca gcgctacgat aataactaaa tgcaatataa tctgccgtgt
   130021 tagcttgcaa gcactgttcg tctccatcta acattactgg tgcacagtct tcttccttcc
   130081 atgtcctgta aatataagct ggataatgcc ctcggcacat gacatcggag aaaaaccatg
   130141 aattgcgttt aaattgcagt gaaccaaata cattctctgg atcacagtca tatgcataag
   130201 tcgctaatgc agaaaagcta cacataatac ccatcttagc atttggatcg attttcttta
   130261 ataattgagt agcacgggcg ttcgctagaa acatatgatg acaggcttga taaatcactt
   130321 tttttgttag tgtagcaatg ggttcaagtt tatctctagc agggaatgta accaatccag
   130381 cagctgcata aggcatacga aaagcattat tgatctcatt aaaggtcatc caatatttca
   130441 ctttcccttg gtagcgttca aagacggtct gcgcataaaa ttcaaaaaag tcgattaatt
   130501 ttcgattttg ccacccccca tactctccta ccaatgctaa gggggtttca taatgactaa
   130561 gagtaattac tggctcgata tcatatcgat ttaatgtatt gattagtctg tcataaaata
   130621 cgagaccagc ctcatttggc ttctgttcgt ctcctcttgg aaatattcgt gcccatgaga
   130681 tgcttgttcg aaaagctttt aaacctaact ccttcagtaa acgaatatcc tcttcaaatc
   130741 gatgataaaa atcaatcgct tcatgagaaa gataatggag tgattcgtct aaagcaatct
   130801 cccaaatctt tttttcttca ttccactgaa tactaggatg ctggttcatg atcccgataa
   130861 gcgtatctgt cacattaggt aatttgccgt cttccaacca tgcaccttca cattgattag
   130921 cagctactgc tccgccccat aaaaaatttt ctggaaatat ttcctgatcc ataactatct
   130981 ctcctcgcta tcaacaattt cttacttgaa gtatagctcg attcatcaaa acaagatatt
   131041 ctaactattt cggcagaaga gaagaaaaaa attgaatgct actcttcatt tttaatattt
   131101 atatataaca aatacataag acgatccccg aaagaaaaca ctcgttaacc atctaagcaa
   131161 acgatttatt ttacttccaa cacaaatgct tcataaggtc gtaaatcaac tttgccgtct
   131221 ggtaactgtt tcagaggata atttgacaca ataaccctta aagcttcacg tggaatagtg
   131281 aacgtctgct tttcactgga catattacaa ataacgagcc attgctggtc ttcatatatg
   131341 cgagaatagg caaagacatg ctcaggcgtc ttttccacta attcatagtc tccccagacg
   131401 atgatgtcat gttttctacg caaatcgatc aatttcttgt acatataaaa aacagaatct
   131461 tgatctgcta acgcttcttc tgcattgatt tctttataat ttggattgac tcgaagccat
   131521 ggaattccag tagtaaaccc agcatgttca cgggcgttcc attgcatagg cgtcctagca
   131581 ttgtctcttc ctttcgcctt gattgattcc aagatttcct cttttgtaaa tccagaagaa
   131641 atcctttcgt tatacatatt gattgtctca atatcttttg cttccgcgat atcatcgatt
   131701 gggcaattcg tcatgcctaa ctcttctcct tgatagatat aaggggtgcc tttcatcata
   131761 tggagcaaga tagcaaacat cttggcactt tcttttcgat acacatcgtc atttccccaa
   131821 cgagaaacaa ttcgcggaag atcgtgatta ttccaaaata aactattcca tccttcatca
   131881 cctaaagatg tttgccattt ggataatact tttttcagtt cagagatact caagggtttc
   131941 aaatcccatt tgtctttgcc ttcttgctga tctaatccta tgtgttcgaa ttggaagacc
   132001 atggataatt catttctttt aggattggaa taaagtttag cgatttcggt agttgctccc
   132061 catgtttcgc caacagtcat cagatttttg tcaccaaaag ttgcttgatt catttcctga
   132121 agatactcat gcagtttagg tccattactt gtgatttctt tatccggttc tttgccaatc
   132181 atatcgatca cgtccatacg aaagccccca atacctttat cgatccagaa attcatcatt
   132241 tgataaatct cttggcgaac ctgtttattt ttccaattca aatcaggttg acgcttgcta
   132301 tacaagtgca gaaaatattg ccccgttttt tcatccaact gccaagcaga accactgaat
   132361 attgagcgca atctattagg ctcttttcca ttgaccggat cacgccaaat ataatagtcc
   132421 cgataaggat tttctttatt tttacgggcc tcaatgaacc acggatgttc atcagaagta
   132481 tgattcacca ccagatccat gatgatacgg atatttcttt tctttgcttc ttcaatcagt
   132541 tcttccattt cttccatcgt accgaattct gccatgattg cttgataatt actgatatca
   132601 tacccattgt catcattcgg agactcgtat actggagaaa gccaaattgc atcaatacct
   132661 aaatacgcca gataatccaa cctggaaata atcccccgca aatctccaat accatcttga
   132721 tttgaatctt gaaaacttct tggatagatt tgataaacaa ctgaatggtg ccaccatttt
   132781 tgttccatga ttttcctcct ataaatggat gtttctattt tttgcttaat catttatttt
   132841 agtctctctc actaaaaatt gtaacgcttt caaatagcta ttgcaccttg ttatcggtaa
   132901 cagaataaaa caaaaaaaca gctgaggaaa ttccctcaac tgttttttga aaggattgat
   132961 ttatgcaggg aagaatgctg atttcacaac ttctttataa acggtgttca ctcagctgtc
   133021 ccttggtatt agctcaaaaa acggcaaaat ataagaaact attttttcgt ttttttctct
   133081 aatactcagg ccagaacgct gatttcacaa cctctttatt tcacattcaa tatccacatg
   133141 aatcccacaa atacaaagaa cagaccatac atgattggag atacttcttt tcctctttta
   133201 gctgctaaca tggtaattgg atagaagata aaacctaatg caatcccatc tgaaatacta
   133261 taagtcaaag gcatgccgat caagatcaag aatgaaggga tcgcaatctc taagtttccc
   133321 cattcgattt gtcgcaaaga ttgtgccatc aatactccta ccataatcaa tgctggtgca
   133381 gttacttgtg aagtaacaac tgatagtaat ggagaaaaga acaagcctaa caagaagaaa
   133441 atccctgtag taatagctgt gatacctgaa cgtcctccaa cggcgatacc agctgatgat
   133501 tctacaaatg caccaacagg agaagtacca aataaggaac ccgcaagcat agctgttgaa
   133561 tcagaagcta aagctttccc tacacgaggc atcttgttgt ctttcatgaa acctgcttgg
   133621 tttgctaatc caactaaagt tcctgctgta tcaaagaaag tcacaagcaa gaatgtcagc
   133681 actacgaccc acatttgaag agaattgatg tcccctacat gttttaatgc aactaaaaat
   133741 gttggtttca aacttggtgc tgcggcaaca atttcagaag gcattggaat caaacctgtg
   133801 accagaccta aaatcgttgt agctgccatc ccgatgaaga tgccacctgg tacacgccga
   133861 acaagcaaga tagcagttac gactaatcca aaaatcgtca accaagtaga accaacgttg
   133921 agtgatccta atcctactaa tgtagattca ttcgaaacga tgatcccacc ttcgctcaga
   133981 ccaaggaaag cgataaatag accgataccg ccagaaatcg catatttcaa atctgctggg
   134041 atcgcatcaa tgatcatttc ccgcagcttg aagattgtga tcaaaataaa aatcaaagaa
   134101 gcaacgaata cgccggctaa tgctgtttcc catggaatcc ccattcctaa acaaacagaa
   134161 taagcaaaaa aagcattgat cccaagagca ggtgccgttc caattggata acgggctaat
   134221 acccccatta aaacacagcc gatcgcactg gctaatgcag tcgcagtaaa cactgctcct
   134281 tcatccattc cagaagcacc taatacagtt ggatttacaa ataagatata agccattgag
   134341 ataaatgttg taaatcctgc cagtacctca cgttttaccg tggtgttcaa tttttctatt
   134401 tcgaagtagg aaagtatttt ttccttcatc ttccatcccc ctaaatccga acattataaa
   134461 taaagtccgt taaaatttcg atttattaat aaaacaacgt gttttatcat atactaaaac
   134521 aaaacataag taaacaaaaa attcggattt taagcaaaat ccgaacgttc catctgatta
   134581 aatcccttta tctcaaagtt catgaacatt cactttggat tacaagaatt tctttattgt
   134641 gttaataaag tttcttcatt ctagtctcaa aaatcaatag tgtgatttga ttttaccatt
   134701 tcgtttctgt tcttctttga tgaattcttt tgtatcgaca ggattcagat tatttagtcc
   134761 gccaaaacct gtatcgacca tttttcccca gccttttgtc ttcttttttc ctgatttgag
   134821 attctttgct cgaagcttct cactatgttt tgctcgccga tacttcaaat aaccttctaa
   134881 tcttcccatt agatccactg tttttcctcc tttttattca atcagacgac tcagcttttc
   134941 ctataacaaa ataattgcct tcagggtcag aaaaattgaa agtcaagatg ccattgttat
   135001 ctgtgatttc tcctggttct tccatgttct cgtagatagt ttcaaattca tccgtaaaaa
   135061 atactaaaga aggcggtggt cctaatacct ctggtgaaaa cttctgcaca aatacttttg
   135121 ggaatacgcc taattctaat tcttttgaga tgctgagtac aatactctta aattcttctg
   135181 gcaattcgat tgtttcagaa atttctgcac caattttttc tacaaagaat cggcaaatca
   135241 tctctacgtc attgacataa agcatcacac gtgttttttg tatcatcatt tgacccttct
   135301 ttctatttga ttttctttcc tgtctataaa ctgattccat tatatcacga aagcgcaaac
   135361 accttgtgtt tgatactatt caagaaaaat aaagcaatag tttctaggat tgctttcctc
   135421 cacaaacttt ttttacaaaa aaaaaaacgg caatgaatgc cgctcttctt atttcgattc
   135481 ttttataatt ctgcttctga ttcatctttg gttagtgtgt gtctaacact agttacgcca
   135541 aatgtttgat cgattttttc cttcaacgct tcgattgcct gtgcgccacg tgccgcttgt
   135601 tcagcattga tggattcaat gaccagcacc gctgcttgtg tttcttccgt cagcatcgtt
   135661 ctttgggctt cacgccagtt gagacagcga cagatcgctc cttgttcatc atagtagatg
   135721 atttcttccg gaagtgccgg agcatcggaa tctgcaccta aaggcaggaa tgattcgcca
   135781 ccttgggctt ttcctaaatg cagatttcct gcgatctttt cgatatcttc tccgccgcaa
   135841 ggtacgccaa aagacaagga aatactatta tagatatcta caagcggatt gattgggaaa
   135901 aattcccgtt cttgatttgc acgtttcagt aaagcttcaa tagaagaacg tgcacctttt
   135961 ttagtcttga atgtggtaaa tgcctgacgc cactgagcaa tgacttcgtt ttggctgaat
   136021 gtttcttctg taaggtaatt tcttgcttct tttgctgcct cattcaataa ttgatgatac
   136081 gtttcttcac tttcttttgt tacgtggtta tcgataccat ttacggataa gatttcgatg
   136141 gttgcttcag gaaatacttc ccagaaattg gtatccacta ttactttttt catctgttca
   136201 cacctcttga ttagaataat tgcttgatga atagatagtc tgtttgggga tcatctccca
   136261 tataaaaaac atgttcgctg tatttgataa atcctttttt acgataaaaa gcgagcgcaa
   136321 catcgttgtg ttcccaaaca ccgagccaaa tggctgtttt ttgcttttct tttgcttttt
   136381 caatagctgt atctagtaaa aatgtaccga taccttgatg tttaaatttt tttcgtacat
   136441 agattcgctc gatttctaaa aaatgatcag ccatttcctc agattgactc gttcctgtat
   136501 ttagtttcag gtaacccgca ggctcttgat cgatactcac taggaaaaaa tcggtttctt
   136561 tatcttttag ctcttctgta agtttttcta gtgcataagc ttgtgtcaag taatcagcta
   136621 aatgctccgg tgaattatct tttccaaatg tatctgtaaa tgtttcgata ctaatttgtt
   136681 gtagtaagtc tacatctgaa ggcgtcattt ttcgaatttc gtatttattc acggcttctt
   136741 cctttcaata gatcctttta ttgccttttt tgacaaaatt ccaatcttcg ctaacattct
   136801 tgcatacttt atttaaaaga tattccaatt gttttgcttc ttcgtcagaa agaccattta
   136861 atgcgactgc attggagtag ttgttttctc gaatgatgaa aggatagatt tctgctcctt
   136921 ttttagtcgg atagagtttc ttgatttttt tattttcttt atcttccaaa cgttcgatca
   136981 tcccattgga ttctaatttc ttgattgctc gggcagtcgt tgtacgatct actttgatca
   137041 tttctgctag tttttcttgg atgattccag gattttcgca aatacgtact aaataaagat
   137101 actgtcctct tgttaaatcg acttctttga attcgatatt gctaatagaa tctagcgctc
   137161 gggcaatcat tccgatgtct cgaaggattt cagccatttc atcccacctt tattttgttt
   137221 gtaagactag ttcacctctt tttgttgcaa atgcaactat tttcaataaa aaaatcaagt
   137281 tcttttttaa taactagtaa agtatattct tttcttcttt tacgaaaaag ctcaatcaca
   137341 atagatctgg tttttgtttt ctaaaataag taactgtttc ttcgttgttc gcttttctga
   137401 tagctttggc aactcttcta tactaaaaaa tcccatgttg gaagtttcat tattctcaat
   137461 aaacttggcc tcttcaccgt ggatcgcaca agcaaaaaca agtttataat actgaaaaag
   137521 ctgtggaata tctttttgtt tattcgtatc aaaaactgct cgcaactgag tagtttctac
   137581 tgttaatcct gtttcttcat agacttcttt acgcacattt tcttcaggag acaatcctat
   137641 ttcagcaaat ccaccaggaa gtgaccattc tttcgtccgt ttatcttcga ttagtaggac
   137701 cttgccatct tttttgatat aggcacgaac atctactttt ggtgttggat gtccttctcc
   137761 aatcgttgtg agcgctttta tttcttcgaa agtttctttt cctatttcac tgattagttc
   137821 caatgaaatc gtccggatct cctcaaaacg ctctttatca aatacatctt ttccataata
   137881 tagaccagct tgagaaagtg cgagtagtct tttgtattga gccaacttct tgttcattct
   137941 cttcccttct tttttagcaa atgtatgact atgtaatcaa gtatagaaga ctggtttaat
   138001 tacggcaaat aaatataatg aaatctgcaa taaataaaag aatgttaaaa aactcgagaa
   138061 caaaagacat tcgacttctc tggggctgtg aataaatggc gttcaaaagc ttgcatctgc
   138121 ggtaataagc cccaccaaac gaaaaatatg acgagctatt cttgtctggc tgttcttatt
   138181 aattgaggca ggacagcttt ttcacaacct ccccactaaa cggtgttctc ctaccaactc
   138241 ctcggtcaca agtcacaata ttcatcaaac atgagaagct gtttttttga aattgctcct
   138301 tgtgactcgg agctgaacga caggctcacg acctctcggt aaacagcgtt caaaagccaa
   138361 tttttcgata ttaagccatt tctttgttac ttattgtcat tgatttcttt ttctaattta
   138421 tccaatagtg gagtgtaatc cacttgagta tagtctgtta catcaaattc atatagtgtt
   138481 cctaactgga atttgtcata ttttcggtcg gcgatgatct ttttgaatgc ttctttcgta
   138541 atatgattgg tccctttcgt tcgatcttcc aatacgtcac catagtgata atgatccatg
   138601 atatagctca aatgacgatc tgattcacga tcacgtttgt accgacgttg ccataacact
   138661 tcaaagtctg ctgttaggcg aatcgtgatc acctgatatc cgtatctatc tgctaattct
   138721 tggagtcgtg ctttttgctt atcactaaaa ggatactcgg acacaatcac tttctttcct
   138781 gcttccatat acaaatcaag tgctttgtaa tagaaaggat aaactttcgt cctttcttgt
   138841 tccgcccgtt cttccaaatt gttaaacccg atggattctg catagtattc cttgatttca
   138901 tcgagcgtga tggcatacat atctggaaat cgttcccgta gtttattcat aagatatgtt
   138961 tttcctgtac caggactacc agccagaaga atgaaatact ttttcatctc atttatttcc
   139021 taagttaatt ggactttcca agttcataaa cagtccaatc ttatgcttga caatttcttt
   139081 tactgcttca tttgctggaa tcacattatg gcgaagagac ttgttgattt ctgtttcact
   139141 aaaggtttct ttagctactt tcgtccagtt gactaaaagc tccgttccaa cattgaattt
   139201 gcggatcccg ttattgatca attcaggata atcttcttct ttcacacctg ttcctccatg
   139261 gataactagg gggacatcaa ctactgcatc gatttctttc agcaagggaa tgtttacttc
   139321 tgtttttgat ttgaattgtc catgattcgt accgatagca atagctaatg catccacgcc
   139381 tgtagcttct acaaatttca ctgcgtcttc cggtcttgta tataccttgt cattttcagc
   139441 gacatggatt ccttcttctg taccgccgat tgttccaagt tctccttcta cggaaacacc
   139501 gtgcgcatgg gcatattcta ctactgcttt tgtcttcagg atattttctt tgaaaggcag
   139561 atgggaccca tcatacatga cagaagtata tccgctgtcg attgcttctt tgatatcatc
   139621 aaagtctcgg gcgtggtcta agtgcaagac tgcatcaacc atttcttctt ctgcaatagc
   139681 tgtcattaca ttgactaaca catgcatgcc gatatattta gcggtatcga cacttgtttg
   139741 aataatgatc ggcgaaccca tttcttttgc tgcgcctagc atagcaggaa gcatttctag
   139801 gttatgcgta ttaaaagctc caactgtaaa attcaactct tctgctgttt ttgttacttc
   139861 tttcaatgtt gtatacatct tttattgcca ccttatcttt ttatttgttt cctttgatcg
   139921 ttacttgttt tgcaatttgt cgcatctcat ccattttgcc catgtagtaa tcgatccctt
   139981 gatcatcacc agcacgagca gcatctgcac gcttctggtt atagaggctc atcagttttt
   140041 tatacccatc tccgatcgtc tgtttatttt ccaaactctt ttctaaatat tggatggctt
   140101 gatcgttcac atacaattca gaaaatttaa gtccaacttg ttcataaagt ttcgctaatt
   140161 tatgcttatc ttgggtagtg gaaatctctt gtttcaattg tgtaatctct gattgaatct
   140221 tttcggtcgc ttctggcgat agggcttttt cttcttttgc cagaactttt ttcggttctt
   140281 tttctttttt cttaaaaaat ccaaacatca ttttccctac tttcaattaa aatgctttca
   140341 aaactgggct taagatccag gcatataaga gtgctgcggc tactgtatct acatcggttg
   140401 ctgtagcatt gatgaatccc atcgaattaa agatcgttac tagcaaagcg ggcaataatg
   140461 taataaagaa accatgagca ataccgccaa tgatcgctcc tcggcgtccg ccaactgcgt
   140521 tgccaaatat ccctgctgtc cctccggcaa agaaattggt tagcatacca ggtaaaatca
   140581 tcgctaagcc gaacatgggc aaagtaaaca tggcaataat cgtaccaatc gttgtcgtaa
   140641 tgaaacctaa aatgacagca tttgggctat aaggaaagaa aactggacaa tctaaggcag
   140701 ggatcgcatc aggaactaat ttcatagcta tccctcgaaa tgccggcacg atttcaccta
   140761 acagtagacg tacaccagct agcaatacat acacacccac tacgaattgg atggcttgta
   140821 aaaaggcaaa catgatatag ttttgatctc ctgataattc agaagcgaat ggttcgcctg
   140881 caaataaaac agtgatgata tatagcggga ccatcacgac catgacagac aaataagtat
   140941 cttgcagaaa ttcgaaatgt gtcggcaact tgatatcttc gatcgacttt ttattttcgc
   141001 ctttctcacc aaaaagctta gcaacaccgg cttcaaataa gtacccgatc gtacaaaaat
   141061 gacctaaagc aatatcattt gatccagtga ttttacgaat gatcggttgc gctactgccg
   141121 gcatagcaat ggcgaaacaa gctccgataa aatcaccgac caagatcaat acgatccctc
   141181 gcagaccggc aaaatagcca aagactgtcg tcatcgttgc catccataaa attgcttgac
   141241 cagttaaaaa aatgtacttc cattttgtga aacgagccaa aataatattg aatacaaaaa
   141301 tggctaagaa cgtcagtgca atatctctac ctaaacccaa atcattcatt gcttgaccat
   141361 tgatagattc aatagaaggg atgatccctt gcatatgaaa tccttcagta aagattttcc
   141421 cgaaataagt taaacttcca acgatgatgc tcgaaccggc actcaacact tgaaatccta
   141481 ggagtgtctt taacgtgcca gagatgactt gtcctgctga tttcttctgc agtagtagac
   141541 ccaacatagc aatcaatgca atggtgatcg atgcctgagt caaaatattt tcgatgataa
   141601 aattgataac gcccatgttt ttcccctctt ttctttttgt atttagataa ctcccttatc
   141661 ttgcagaact ggggtgattt tttcttcaat ttcatttttt gaaacaatat ttttcaaata
   141721 gatcatcgcc gttttaggat caactgcgaa cttttcgaac tgcgaacgaa aattttctgc
   141781 tgtgatgatc acatctggtt tcatggaaac tgcggaagaa atatcacaat ggtccagttt
   141841 ggcttctact cctaatttgt tcaaaacatc ctcagcagac atctgtgctg caaaactact
   141901 tcctaaacct gcaccgcata cgaataaaat gttcaatttg ttcatctttg ttctcccccg
   141961 tatcatttat tatttctcaa ctactgaaaa aagcagttgt ttgaaatctt cgatatttgt
   142021 gcattcaatc aatcgatcca acttctcttc gttgttgatc aattcaatta gttctttcat
   142081 gatgttcaga tgcgagtagg agtctactgc tgccaaacaa aaaataatct ttactggatc
   142141 catttcagga ttaccgaaat cgattggttg ctcaatcgta gctacgctga ctcctaattt
   142201 attgacccca tcttctggtc gggcatgggc tagtgccatg tgtttgccaa tcacgatata
   142261 cggtccgtaa tcattcactg cacgaatcat cgcttcgaca tagcgctctt cgacaatgtt
   142321 ttctttaacc aatggtctag cagctagttc aatcgattcc tcccaagtag tggctttttc
   142381 tttgatcatg atattgctgt ccgtcaaaat atcttttaac ataggctgga tctccctttt
   142441 gttgatttct aaattgtttg tttcgaataa tttttctaac ttgccataga tgattcgatc
   142501 tactcggcca ccactttctt tcatgacatc tattatttga gtgaataact ccgtcgattc
   142561 atgactgtta ggctctaacc gctgtagttc ttcatttctt ttcaaaaagt cttctataac
   142621 caagatattc gtctcagtta aaatcggatc gacaactaaa agcggcttat ttcgataatt
   142681 caattgaaag gtgctgaaaa ccagattgac atccaattta tctactaatt cgatttcttt
   142741 tgaacttaaa actgcagtaa tctcgatctg aggaaacttt tctttcagat tctctgctaa
   142801 cagatttcca gtagccatcc catggttaca gacaacgact gatttataaa cataattcaa
   142861 gtctcgcttg attacactgg cgatcgtcga aaagtggatg acaagaaaag ctatctcgtc
   142921 ctccagtatc ttgccaccaa ttacttcttc gatcgtagga acaaaatgag tgactgcgcg
   142981 gtagattggg aaataatttg ttcggatgtt ttctttcaat ggattcatga cttggatatg
   143041 attcttgatt cttacaatca gtgcagccat gtgcttatag agattttcga ataaagcttc
   143101 ttcctttaga tggaaaggta cgtgtgtctc gttctctaca aattggatca attggatcgt
   143161 tagtaattga gcttgtaccc actcgattga attggagata tctctagcat tgaacgtctc
   143221 aatagtgaaa cgaagataat ttctttctac ttgcgggaca ttgtccaatt gaaattcctc
   143281 gatcatgtgg tcaataaatg cagaaaagct actgtctttt atttctgtat ttttccaatt
   143341 aatggcagag ataaattcat gtttcctgat tcgctggatc cagatcaatg taaaaagcag
   143401 gatttgtttt ttataaatat catcttcttg tttcaacaac ttattggaat agatctcctg
   143461 tatttttttg atttccacca aaggaaaata atggagaaag attttttgag ccggtgttaa
   143521 ttgtgcatct tgattcataa agaagtcggt cattcccaga ttctgattga taaaatcata
   143581 gatcatcgta cggatagatc gttctgaacc tttataaacc agtccttgct ttccataact
   143641 gacgatctct atcccataac tgaccagtgt tgctcgtaac cgtctcatat cttcatctaa
   143701 tgtactttta gagatttgaa attcttcttc ttttttgttt agatggatcg ggattcggct
   143761 gtaagcaacg gctaaaacta gatcaaaaat acgttcgcgc cgattcaaaa agccgtcttt
   143821 cacatctttt atttcagttt ctaatcgagc ttgcttttcc ttttccagct tcaacaaaaa
   143881 acctttgttg cgaattgtac ggatctccgg aagcttttta ctgctcaacc agatattcgc
   143941 ttcaagaact tcctgacgga tcgtccgctg actgacattg aactcacttg ctagatgttt
   144001 tgcttttact ggatattggg ctgtcatgat tctgtgaagt atttcaattg ttcttgtttt
   144061 catagaaatg atctccttct gatttcaagt atatggttcc gcttacataa taaaaagtag
   144121 atatttctgc cacttgaagt ggaaagaaag taagcaaagc aaacaaaaaa taagccatat
   144181 gctttttcat ctcctcaacg aaaaagacat acgcctatta ttacaaaaat tttgcccatc
   144241 tatacaaaaa agaggttgtg aaaaagctgt cctgcatcaa gtaataagaa caactaaact
   144301 aaaatagtgc ttcctatttt tcgtttggtt gttcttatta tcgcagatgc aagcttttaa
   144361 acaccattta gtggagaggt tgtgacagag atgttcagcc ttgagcgata agaagcgatt
   144421 ttgaaaaatc gcttcccata ttttacaaaa tcgtgcctta ttgccgatag gctatctctg
   144481 gcacaccgtt tattcagaaa aaggagctgc gacaaggctt ttgtcacaac tccgttcata
   144541 aatatttcct gtcaatccag cataatcggc tgaataaaat cggcttgcca tcttttttct
   144601 ttctcagaaa aatcaaaata ccatatctga gaaaaatact gtcgttgtgt cttacttcct
   144661 gagatcaatc gcccatcttt tcgatcgact gaataatcac agcatctgaa atcaattcgg
   144721 atggcaaaac tattttcgtg gatctgtcga taatttccta cttcctgaat agttattttt
   144781 ttagtatgat ttcttacacc gtctgctttg tttttttgca gaactttctg atgttcggca
   144841 aacagcttgt ctgtataaca gcttctggct ttttcaggag tttcttcttc ccaagcggat
   144901 tggatcttca tgaatatctt ttggatttcc agaaactgtg ctttcttttc tttagccgtt
   144961 cctgacatgc gggacaatat ctccgctttc agccttttct tttgtctttt attcttgacg
   145021 atagaaaaag cagaaacccc tcctactgac aaaacagcta atgcaagaaa tcccgtttgc
   145081 tcataactag aaggacctgt acctggacca taatacccat aagaatctct gccgtaagaa
   145141 cgactgccaa aataactgcc cccatatgaa cgaccaccaa atgaacctct gcccgaactt
   145201 cgaccgctag atgtacctcc accatgacca cccgcgacag cgaatccttg ggtcggcaga
   145261 gcaaacaaac ataggcccac taacaaaatg attgctaaat aattgatttt tttcattgtc
   145321 ttcctcgtta tcttttatta caaaaaacta tttttatgat agccttgcta aaaggaagag
   145381 tcaataacca gatgcataaa ctgttttttt agcaattttg tcttatttag tcattgagta
   145441 acatcggaca aatgtatgtg tcggcagtcc ataattcctc tatcttcagc atgaacaagc
   145501 ttgcagacaa gagatctgcg cttcctccag gagagatttg gttttcctga caaaagtgca
   145561 acagtgctgt aaatggacga tttggtaaag cactttgact agcagcatga gcaagttttt
   145621 gcatttccac taacgttttc tgatcactgc gatgcaatac gcatgtgtca tctagcgaac
   145681 tcatcaaaac taacaacata tgcatttgtt tctgtacata tgaatcatta tctagctcct
   145741 tagctgcttg aattgcaagc ctgatatgcg gataccctaa tatcgcttct tcatatgcac
   145801 catttacgcc atatttttgc ttcaccctat gaccatgagt ggttttttta tgacgatatt
   145861 ttgtatcagg aaaagcagca agcttgctga catcatcaag tattttcgat aaagaaaaag
   145921 gctgttccat actgattttt tgtgcaatga cactgatcaa tagccccatt gcccaaatcg
   145981 ctcctttatg ggtattgatg ccatttgtag caatcagcat tgccttttcc gcttttcgcc
   146041 caatctcagc aattctttct cttaactcct gatcaatagc atgatgccat gctatttgag
   146101 ccatttcttc aaaaaaagga gttagcgtct tagcagactt aagaaataaa gcatagtcca
   146161 tatcggaatg tgcacccgca tccagtgcat ccactaatcc aggttttgga cttaatgtta
   146221 cttctgcgat caatgcttcc tctaccaacg cagcgagttg ctgagtcact gctttttttc
   146281 gttcgtcatt tatcatgaca ctcactcctt cttcctacta ttacttgctg aaaccttttt
   146341 tgatagctac ccaaatgata tgaagtaacc agcttaaagc aaatgcacaa cttgccgtca
   146401 ttagataagc tacaagaatc atgactcctg aaggtaactg cagccaacta tctttaaaca
   146461 ataataacag tacttggaaa acaaatacat tggctaaata cgtacgataa gcataaacag
   146521 acaaccattt gaacaatggc aattttggcg aatcgtttac aatcattttg gaagcgccta
   146581 tgaagacagc aaagatgatg actaaactgt ataaactttg gatcgtattc aagtaaggtg
   146641 cattcgcaaa gctcaagtct cctggatgtg cgagcaatga acggacagaa aagaacgcga
   146701 taactaaggc aacaggtaag aaaagataac gtactctgtc caaatattga tagacttttt
   146761 cgtgataaac aaatgcggct accccataaa tcatgaaact agcaacaaac cgatctaata
   146821 agtaccagct gtcatgataa ggcccagtca atacttgtgt ttgatagaac agataccatg
   146881 cgacatataa aatcgttgaa ccaatcaata ctggccatac atatttttta ttagcaaata
   146941 ctttgtaacc gagccaaaca aaaaacggca tgaacaattg gatctgcagc atcataacgg
   147001 tataccataa atgaggcgct ccatcacctg tgacatattt cagtaaaaag cttgcagtat
   147061 ccgtatacgg agtttgttgt tggactgctg gaaatagcca aagataagcc gtcgtccata
   147121 gaagatacgg aacgactagt tcaaaaaact tttctttcaa aaattcccaa taagacaaat
   147181 gctgacttgt ttttaccata ttataaacaa ttgcaaaaat aaacattggt gctgtgtatt
   147241 taacgatgac gtaaaaggta ccaagaaaag ctgtatttgt tgcgctgtgg ctgtttgcca
   147301 aagcaaagct caatatcgtt tgcatcataa cagccgttac agctgatact ttctggaagt
   147361 cacttacgtt gattttgatt tttttgtttt caaacatctc tttctctctc tttttcttta
   147421 ttaccaaagt tctttggtta atttaggtcc ttcgactgtt ttcaatagaa tttttttctc
   147481 tggctctctc aaatactctt ttagtgaaaa accgccttgc cgagtcacta cttgggtatc
   147541 gaattgctca aaaaaagcag gatgcgattg aattacctga attggcaatt caatcggtga
   147601 atttgcgtac agcagcaaat caaaatcact ggtttctttt actgccggaa tcccagtcga
   147661 taattcaaat cctaagctgc cgccgattcc ccatttacat cctgataata tgtttctagc
   147721 agcatgaaat tgctgataaa caggataatc catgattttc tcttgtctat acgattcttg
   147781 ttcgatgatg tcccacggat gaatgacttg tttgacggca tgttttgaga tttctgttga
   147841 ccatctctga ttgcgggcag gtccacgtaa accaatcggt agtatttctg cgtgatccgt
   147901 cgacgcacga cgaactgttc cgaacatctt ttcagttaga acgacccatt caggcaaggt
   147961 gaacccttct atttcatgtt tatcaaaaag gacaatatca tgtgcttgaa tcatttttta
   148021 tgcatcccat tcttcgtcca ttttggcacg gactttattt gtttcgacac gtccgaatgt
   148081 tttggctgtt tcgtttgtgt atcgatttgt cagcatcgtg tcatttgtat tgcggacatc
   148141 ttgaatggct tcattgattg cttcgatgac tttgctgaca ttttgttctg aagcagcttg
   148201 gtcggtgata tcttctagga aatgatagat cgctcctagt tttgtataat tattgatatc
   148261 gtaagcgata gctggaactt tttcagcagc tgcttcgatt tcagcaaccg aacgttttgt
   148321 cacacgtgca gcactttctt tagacatcgc ttggacggta atttctttat tgtttaaagc
   148381 aatcaagcgg cttgattgta atccatgtgc taaaaatgca cctgaaatag catttcctgc
   148441 aatcaatcca ataactggat gtccagcttg acggagtttt gcataagcag cagcactatt
   148501 agccaaagcc acatggatac cgatcaattc ttcgttatag ccgtatgctt ggcttggtac
   148561 atcgatcaca acgatgattg gccgtttcac ttttttgtct ttatcttctt cgtaaacgtg
   148621 atccaaaatt tgtcccatgc ggaaaccttc aactaaacca acttcaccgt ttcgtacacg
   148681 gtacatcggg tttttaggat caggtacgat tgatgtcacg atggcttctt ctatgaattt
   148741 acttgattta ccataataca cagtactaat agaagaagtt ggatttttca tgccagttag
   148801 tgccgcaaac caatcgtaac caacacttgc tgcagctggt tcatttcctt ctgctacttc
   148861 tggtaagtca attgattttg cttgatggtt agcaattgct tcattgtaat cgtcaatggc
   148921 cattggtttt gaaagatcta aagaatcaag taatgataaa taaaatgctg agctttcact
   148981 gcgatgcgtg tcttttcgtt cgtccattgc tgcgatgaca gcagctttga ttgcttctac
   149041 actatcagtc actaattcat caatgatttt tgattctacc cgttgacgag atcctaatgt
   149101 attccaaatc aagtctttgt cactagaatc aaattctcga acgcctgctt cttgttcaat
   149161 aacttctggt ccattcaaac cgactctcgc tttttttgtt gcgattaaat aactcattaa
   149221 tgctgaagta atcgacatac cgccaaatga tcctacacgt cctggaatca aaccgatgac
   149281 tggtacatat tgttttagag caatgattac atttccgatt tctgaaatag ataacagtcc
   149341 gtagtttgct tcttgcaaac gaacaccacc tgtatctagt acaatgactg gaaagatctc
   149401 atttcctttt ttattttctt ctaacacatg ttcaagtgca gcaacgattt ttgcaccgga
   149461 aacttcaccg ataccgccac cttggaattt tccttccata gcgattacta ctgcttgttt
   149521 gccattgatc gtgccacggc tgacaacgat cccgtcatca ctttcaggga cgattccttg
   149581 tgctggtaaa cttggcgcga tgatttgatc gaatggatca atcaattcac gtccattgtc
   149641 aagtagagcg ttcactcgtt ctctggcgtt taattctaca aaactatttt tcatctgaaa
   149701 gttcctccat tgcttgcgtc aatcgtaggt acacaactcc tggtgtagca ccgaagtcat
   149761 tgatcacgat atctgctgaa attggataac gatcaaaaaa tctcgttaat acattgttcc
   149821 atacttcgcc gaagccatcg cttcctgtac aaatttttac agtagattct gttttttctg
   149881 ttggaaacat caagatttcc aaatctcctg aaccgaccac tcctacatgg attttcttat
   149941 tgatcggctg tttcgttgga tatttataag ctaattgttc catggatctc tccccttttt
   150001 gtaaaacaga gcatacacgt tctgcttatt cgtctttctt cttccatctg ggtaaatggc
   150061 gacaaaaggt ttttctcgcc aattttatga ccaagttctg aatttcattg gtggttcata
   150121 caggccatct gaccattcga tcaaatcatc gatggtttgt gcagctaata atgaacgttt
   150181 cgcttcacta cgtttgatgc ctagatcttc tggtaatttc acgatgccgg ctgcacgcaa
   150241 gctatctagt gattctttcg tgctagtcat tccaagaggt gtaacaccgc caattgctgc
   150301 aattgctgct tgtcgttctt cttttgtttt tgctttgtac aaataagcaa ttccttcttc
   150361 tgtcacgata tgtgtagtat cttcgctata aatcatcact ggtgcattgg ctaagcctgc
   150421 ttgtttttga acagctagtg catctaattc ttcgacaaag actggttttt tatttgaacc
   150481 atatgtttca accatttgaa caactaattt ttggcctttc cctaatggat catcattgtc
   150541 gcgaagtgat tgccatgctg gtgtagaatg acgacgaccg ccaggattat gtcccatgtt
   150601 aggcgcaccg ccaaaaccag ataaacgtcc ttttgttacg gtagaagagt ttccttcgta
   150661 atctaattgc aaggttgaac cgataaacat atcgatggca tattgtcctg cagcttgtga
   150721 taatgttcgg ttactgcgca tcgtgccgtc tttaccgaca aaaaagacat ctgggcgagc
   150781 agcaatatat ttttccatac caacttcgcc accaaaacta tggatgcttt caacccaacc
   150841 tgattcgatg gctggaatca tcgttggatg tgggttcaat acccagttct tcgcgatttt
   150901 cccttttaac cctagtgatt caccataagt tggcagtaac aattcgatag ctgctgtatt
   150961 gaatccaata ccgtgattca aagattgtac gccgtgttct gcgtagattc ctttgattgc
   151021 catcattgcc attagaattt gcaattctgt gatgttttga ggatctcgtg tgaataaagc
   151081 ttctaattga taaggtttat ctgctttcac gacaacgtct acccagtcac cagggatatc
   151141 tacacgtggt aaagaatcga caacttcgtt gacttgaacg atcacgatac catctttgaa
   151201 agctgcagct tcgatgattg ttggtgtttc ttccgtattg aaacctgtgt acaagttgcc
   151261 gtctttatct gctttatctg cagctactaa aacaacattt ggaatcaaat cgatgaataa
   151321 gcgtccataa agttccaaat aagtatggat atcacctaat ttcattgtgc cgtcttcaat
   151381 catttgggcg acacgcaagc tttgtgcacc agcataagag aaatcgatct tgcttgcgat
   151441 tcctttttca aaaatattca aatgttctgg tcgtgagata ctagacatga tcaaatgcag
   151501 atcattcact ttttctgcat ctactttttc aagactttct gaaagaaaac ttgcttgttt
   151561 ttgattgtcg ccttctaata caactttgtc gccgggagca atcagttttt ccattacttc
   151621 tacgattttt tcagtttcta catacttgcc attgagcaag ttgctgattt tttccaatcg
   151681 ctgcgctttt ttttcgcgtt tagaagccca gttgcggttt ggtttttcca taattagtca
   151741 tctccatttt tgatatagaa acgtggcgtc atcaatacca tgttggtcta gattgatcgt
   151801 acggatccct ttatctacac caaattttgt atgaatcagc tttgtcaaag tattgccggg
   151861 gggaaattca atcgtcagat ccattcctaa ttcttttgcc aagtccatca tttggttcca
   151921 ctgcacaggg aaagctaggt tttccaacaa atctttacga atctcttctg cgtcctgagt
   151981 ggctcttcca tccgtatttt ttatatacaa acatctagca tcagatagat ggacagactg
   152041 catatacggc ttgaatttct tgaccgtatc attcatcaag agacagtgag atggcacagg
   152101 gactttcagc agcttcgctg tttgcgcttg gtgccgtttg gcttctgcca acgtaacgga
   152161 taaaccttcg atactcccag ataacgtatg ttgcatcgga caattttcat ttgacagata
   152221 aactggatgg tcaggatcaa atgtttttgc tacaatttcc tcagcttcgc ttctcgtcac
   152281 acctactact acgcccattg cataaccgct tggataagct tctttcatta agactgcgcg
   152341 gtgatagact agttccgctg cattctcaaa tctcaaagat cgacaagcaa cagctgcaca
   152401 aaaagcacca atcgaatgtc ctgctgcaat atcaggctga ataccgtttt tttccatttc
   152461 atctaaataa aatactgctt ttgtcagtaa tgctagctgg ataaaaaccg tatcttgata
   152521 gttttcttct ttatcaacta accgataccc cgtcacattt tctaaacgtt ccatgtacat
   152581 ttcagggata tccgctaaca tccctaactt ctgactgcct tgtccaggaa ataagaaacc
   152641 tgtactcatg agcctcgcct cctcagcact tactttttcc actgctatct tagtcaattt
   152701 ctgctataat aaaaaatgcc aaaaaaagaa aaaaccataa caaaaaggta tggatgggat
   152761 ggataattat gaaattgctt catctgcagt attttaaaaa agtattcgaa acaaaaaatg
   152821 ttacccaagc agccaaagaa ttatttattt ctcaacctgc cttgagccgt gcgatcaaac
   152881 atttggaaaa cgaattaggt gtccctttgt tttaccatag cggcagaaac attgagacga
   152941 ccgtttatgc agaagaattt tatccatatg cagtcaagac attagacaca ttagaagaag
   153001 gaatcaaatt attgtcttcg gtcaatgaga agatcgttac ttccgtcata ttgtatttag
   153061 aggtagcctc tgtttctatt ccgaacttgg tccgaatttt tatggaaaag catcctgata
   153121 tccaattaac gatcatgcaa catcatttac cagatgatat taccgatcct gtactgtaca
   153181 tcacttcgga gatgaagcct ggcatgacca atattcctat catgaaagaa cctgtttatg
   153241 tcgccattcc taagaaacat cctcttgcta aaaaagaaca tctgcaatta gaagatatcc
   153301 aacgcacccc catcttgatg ctgtcaaaga gcaacgcctt ccgtcataca ctggatgcag
   153361 cacttgaagc gaaaagtatc gaattgacga tcagttcgac gacagatgat cctgcgacat
   153421 tacgttctat tgtcaagcaa ggattagctg ttagcttttt cccaaaagtt tcttggtctt
   153481 acgataaaaa tgatcctttc gtcttgcggg aaatcaaaga tttgcccttg acacgaacaa
   153541 tttatttatc ttctagcttc acagaagatc atcctttgat caaaatgatt gcaaaaacga
   153601 tgcgggaatt ttatttagga aaataaaaaa aaaagagctg ggacaaaatt cttgtcgcag
   153661 ctcttttttc gaacaaacgg tgttccagaa gtaatttctt agaaaataag ccgaaatttc
   153721 ccaaaaattt gagaagcaat tttcgtaaat tccttcttat ttcttgaagc taaacatttc
   153781 tgtcacaacc tcttctctat tgtcctagac attcattgcg ttgatttaaa acttccatca
   153841 atcaaatctg ctagttcatc tagcttttct attttacgta gatcaataga gatccaatgt
   153901 tctttattca tgtgataggc tggaaaatac ccctcttttc ctcgcaaaat tccgccaagt
   153961 tcaggatcga ccttcaaatc aagaatattg atgatcctat ggtcacttgc atcatcatag
   154021 attttttctt ctggaacaga catcaggacc ccaaaccatt ttttgctttt ttgatgtctg
   154081 aatacgcaat aatcaggaaa ttttttaaaa atatattctg gagacaaatt gtatgtttca
   154141 ttgatgtgat cgattagttc ttttttcgtt agcatctgct tccatctctt tcttattgat
   154201 tcgctttatt caaagatacc acgtaagaat agaaaaatga atacaagtag ttgctaatca
   154261 aatacttcga tatttttctt ttttatcaac tcttaaatgt tcaatccgcc tgtgttggtc
   154321 ttgctaccat ctactattaa aatgtttatt attgtttgcc cacctatttt ttgattttag
   154381 tggtatcatt tttcaagttc atgatgaaat tcttatcatc agtaaatgct ccagaaaaat
   154441 aaacaatgat tgaaaaatca gttgaaactt gaccaccgtt tattttctcc gtattcttag
   154501 aatagaaggg agtctgattg atgtattcac taatgaaaaa aatcattacc gaaaaagata
   154561 ttcgacgtca tgtttcttta gtagaacaat tgctgaatca tacaaagata accgtaaatg
   154621 aattagctga aatcataggg acaaccgaac gaacgatttt ttctgacctt caatctattc
   154681 gctctcagct gcccgaaggc tgggacatca tcagcgatca agcaggaatc agtttgcaaa
   154741 accagcaaaa tttattaaca aatgaccttt gggagatttt tttcaaacaa tcagtcagtg
   154801 tcgaactgct gaaaaatctg ctttttacaa aaaaagttgc tgtccctgat tttctagccg
   154861 accatgggct ttcttatggg acattgaaaa gacatgtgac taaaatcaat cagcgtttag
   154921 caagttacga cttgcagatc gatttgacga aatatacagc ttgtattctt ggaaaagagc
   154981 gtgcgattcg tactttttat catcgattgc tgattccttt cactcataac aactattttt
   155041 tcgaggatta ttcgatccat gaatcccatt attttcaatt tttaagaaac ctcagtcaaa
   155101 ctgaactagc ggttgaaaca gaagagattt tcggaacatg ttggttcttt atcaatacga
   155161 tccgtataaa agcgaattgc cgattagatt cttctatcca taccaacagc acactctcct
   155221 ccctgtatga ctctgcattg aaaaaattgt atttaacgga aggtatttat cttaaagaca
   155281 ctgagctttc ttttgcttct ttctgctttc tggaaagttg gaattacaac aataactatg
   155341 gacaagaaac cgctcgctgc ctgcatcatt ctccattttt agaggtcctc gaaacgtttg
   155401 tagaggaact agcttcagag ctgtctcttg atcaactaaa aaaaacatct ctgactgata
   155461 acttggctct cctcatatta aaatatcatg aatcgccgat attgattgaa gcattggacc
   155521 gtcaatacca tcgtttttta gaaacatatg atcagcaata tgcacacttg tatcaacaga
   155581 aagagaattt actgaacgat ctaaaaaaag aaatagaaat caatgaacca aattactttc
   155641 tccaactctt gtctctactg atccaacaaa cgattttttc tatcaaaccg aatttgttca
   155701 atgtctattt tattttccaa ggagaacctt catggaaggc gttcttgcag caggaattaa
   155761 aagattactt aggaaaacgt gtctgcttct tacctatcga actaaccgat ctttccacta
   155821 tttcttttga aaaaacagat atcttgattt ccaatttccc tctagattct ctagatatcc
   155881 ctattgtata catttcttct attccaacga aaaatgagct caatcgtttg actgaactca
   155941 ctttcaaaac ttttttatag taacggctag cgactgtatt ctctagctgt tttttctttt
   156001 ttgcgaaaca gtttgttcat gatccctttt tctatttcta caactaagaa tagaagaatc
   156061 acatttgctc caatcaataa ctgttgtgtc atcgttaaac ttactgtacc gatcagctgc
   156121 tggccgactg gtagaaaaat aaccatccct tgcaataaag caaggatacc taatgaaaga
   156181 aaaagcgctt tgttttgcaa aagaccttgg ttcaatgacg gcttggacaa ctctctgcaa
   156241 ttgatcatgt aaacagcttg agctaagacg atattttgca gaagaatggt ttgctgtaag
   156301 ctttgccctt caaactgcat agccaataaa taggcaggaa ccatgatcag tagggagaca
   156361 tagatgatcc gaaacaaatg ataaccagat aggattcctt gctttggatc tcttggtggg
   156421 cgcttcatga tttctggatc tggcgactcg aaccctagtg cataagataa agtgattgtc
   156481 gttaccatat tgacccataa aatctgtact ggggacaaag gtagcgggcg attcagcata
   156541 agtgcccaaa tcaagatcaa tccttgagct aatgcagttg gcaagaagaa attgatggtt
   156601 ttttgcaaat tatccaaaat ccgccggccc tcttttacgg cttttgcaat cgtatggaaa
   156661 ttatcatctc ctaaaaccat atcagctgcc tgtttgctta cttcactacc tttgattccc
   156721 atagcaattc ctacatcgga tcttttcaaa gcaggtgcat catttacgcc gtctccggtc
   156781 attccgacga tttctccatt tttctgcaaa gctttaacaa ttcgcagttt atgttctggt
   156841 gtcgttcgag caaagacatc gactattggc acttgctgaa tcaactcttc atcagacata
   156901 agatccaaat cgatcccttc taaaactttg gcagtatgtt ttaagccaat ttgttccgca
   156961 atcgcttttg ctgtgtcttt gtgatcccct gtaatcattt tcactgagat ccctgcttgt
   157021 tggcattcct ttacagcttt gactgcactt tcttttggcg gatcgatcaa tccggcgatc
   157081 cctgcaaaag ttaattgggt taaagtctca tgcgtgagtt cctgtttcga atctactttt
   157141 ttataagcaa atcctaaaac acgctgacct tttctcgcaa attctgcagc tgtctgactc
   157201 catgcttctt gttctgcaga agaaagagtt gatttagcaa ataatacttc tggtgcacct
   157261 ttgacgtaaa tcaccgctcc tttttcctcc gcatgcatcg ttgccatata tttgtattca
   157321 gaactgaacg gaatctttgc ttctattttt ttcaaaggta gattggctgt ttctgtgtgt
   157381 cgaatcagcg caacttctgt cggattgcca cttaaatttt ctgttttctg ttcttctttt
   157441 gtttttaatt cctgacagtt tttcataatg gacaacacgc aggcttcttc ttttgcagct
   157501 acatccacaa ctgtcatttc attttttgtc aatgttcctg tcttatctga acagatcact
   157561 gtcatagaac ctaatgtttc taccgaagga agtcctttga tgatcgcctt ttcttttgcc
   157621 atttcatgta ctccaacgga tagaatcatg gtcaaaacag ctggcaatcc ttcgggtacc
   157681 attgacacca ccaaagcaat cgtagccgaa agaaggatat gccaatccat accatatcga
   157741 aatgtcgtaa aaataactaa gaataggctc aaacaaagaa tgccttgaaa aatttgtttg
   157801 tttaatcggt tgattttttt aatcagaggc gtcgtttgtt gttcgaccga ttgcaatgct
   157861 tgattgattt taccgatttc tgtcgtgttt cctgtttcta caacgacacc gactgcagaa
   157921 ccagattgta caagcgttcc tgaaaaaccc atatttttct ggtcgccgat cgattcttct
   157981 tctgtcaaaa cggcatgact tttttcagat gcttctgatt ctcccgtcaa aatcgattct
   158041 tccactaata aatcatgtgc ttcgattaat cggatatctg ctggaacgac atctccggca
   158101 cgtaagacaa tgacatctcc ttttaccagt tctttcgcag ggattttttc ttgcatcccg
   158161 tttgatagta ctatcgcttc ttgtcccatc agctgcttca aaccattcaa tgattcttcc
   158221 gcttttcttt cttgccagta actaacgagt ccattgacga tcactacgaa taaaataata
   158281 cttccttcaa tatattcact agaagcaaat ttcaaaaaag aggcaatgat caacacgatc
   158341 atcagcagat cagtaaaatg ctttgctatt tttttccatc gttttgtctg ctgccttgct
   158401 tttatttcat tatatccttg atcagtcagg cgtttctgtc gttcttcttg cgacaagcct
   158461 tctgttgatg tttgatagtt tttcaataca tcttctaccg tcaatctgta ccagttcatc
   158521 ctatcccctc ctgtttaatt gatactgtta ttatacgcag ggaagttttt tcaggcgtat
   158581 cgattatttc aggggggtct gaaataattc gttttgcaaa atgtatctgg gcctaactga
   158641 tatttctatt gcttattctt ttatatacaa aatttaagaa tacaaaccag ataaccaata
   158701 aaaaaggaat aaagcgtgtc gtgctttcga ataacaagct gaaagcaatt gaagtaaaaa
   158761 acaccaacaa agcaagatct ttatatcttt gtgtagtgtt ccgtttcttt tctttaataa
   158821 attgaacatg tgcacacaag atcgaagacc acacaaatag aaaacaactc gttgtcatgc
   158881 ctgccaaaag ctgaaaaaac aatcgactat cagctacaaa aaaatgtaga caaagaccgg
   158941 caaaaaataa cattcctgta attaaaatac cgtgtaaagg tacgcctttc ttagaaagcg
   159001 cacaaaacca atggggcaaa cttttttctt ttgctgtttg atataaaatc ctgctagtac
   159061 tgtagactgc actatttgct gaggacaaag aagcaaccaa aatcattaga ttgacaattg
   159121 ctgctccgcc ttggcaatgg atcacttgca gcatagtcac taaaggactt tcttttaaat
   159181 ctaaacaatg ccatggaaca acaaataaaa tcgacaaaat cgttcctata tagaaaaaga
   159241 gaatacgcca aggcagacag ttgattgctt ttttcaaatt cttttgcgga tcacttgtct
   159301 cgccaacggt taagccgatc atttcaattc cagcaaaact gaataaaacc ataggaaatg
   159361 agactaccat tccagcaaag ccaaacggta gtaattcatc gatctgtcca aaattttctt
   159421 tgattccgat agactgggta tgaaaatctg agacactcaa tcctataccc aataagataa
   159481 aaaggaaaat ccccaagatc ttgatgattg agaaaaaaga ttccaattca ccaaaccact
   159541 tgactgcaac aaggttgact gccattaaga tcattagtgc gctacctccg cttatcaaag
   159601 ctggtacatg tacaaaccag aaatggatat acaatcctat tgctgttaat tccgcaagtc
   159661 cagctccaag ccagcaaagc caataagtcc aattgacaaa aaatgcccac tttttgccta
   159721 aataatagtc aacgaaatca ctgatagagt taaatgtact atttgctaaa aataaatcac
   159781 ccatggcccg catcaaacca taaatagcca aaccgcatat caaataaacg agaataacag
   159841 ctggccctgc tgatgcaatt gcctttgctg aacctaaaaa taatcctgtt ccaattgcgc
   159901 cacctaatgc gattaactgg atatttcgat tagttagagt ccgtttcatt gccggttttt
   159961 ccatcaagtt cacctttttc tttttcaagc agcatggcga cttcctgttc ccaagaaggt
   160021 ttctttattt tttcaataca gagtggtact acaaacaaaa tgacactgat ggctgtgact
   160081 gcaattagat tgatccatgt tccagctttc atcgtcagtc cgacagaaaa tccgattgcc
   160141 gcaaataaaa caataacgac agtccaaact ccaagattgc tctttttctc tttttttcca
   160201 attctaaatg gtcgattcaa ctttgcatgt gtataacgca atctcaaaac tgcgatcccc
   160261 atgatgacat agacgataca gtagataaca gtagttgaat ttacgagcat caaaaatgct
   160321 tgattgacgc caggaatcag caaataaaaa agtgcaaaga ttgagataat gacagactga
   160381 gtcaaaataa cggatttgga tacgtcaaat tgattcgtct tccaaaaatt gaattttggt
   160441 ggatacgcac cttttctagc actttctgtc actgtctttg ctggtcctga ggcccaagca
   160501 gataattgga ctgctacacc aatgaagaca agtaaactaa acagattcac aataagatgt
   160561 ggcaaaccaa gaatttggca ataaatcgaa atagattgcg cgatattatt caattccatt
   160621 tgtccttttg gtacgacatt tgctacaact aaagcattca aaatattgac gaaaaatata
   160681 aaaattaacg cggcaaatac tccgcgaata tacgttttaa ctggattttc caatcgagtg
   160741 atatacacag aggacatttc gataccagta aaaataaaca tgatcggcgc aaaataaaca
   160801 aatgaggatg cagtcgtagt atctggtatt aatttgtccc atgaaaaact gcctaatgtt
   160861 ccggttggta cgatcccaac tttgatccac gcagcaaacc ctaataagag catcatcgtc
   160921 aaaggcacgt acaatcctaa ccaaacaccg acttttccgc cgatttttgc catatcaaat
   160981 ttcaaattca aaaaagtgat gatccaataa acgactaaaa tgacaactaa tgtaaatttg
   161041 ctgttcaaac caagcggcac attatcgata atattaccaa acaacggagc gagtgctgaa
   161101 gcgaccatca ccatcccagg aaacatttgg acccataaca gccatgagac aacgaacccc
   161161 catttttttc ctagagcatt cgatacccaa agttctggac cacctttttg gggaaacatt
   161221 ccagcaaatt caccagagat caatgagatt ggaaaagcgt acaataatac tgcaaccagc
   161281 atgtaaaaaa tcatcgtcca gctcgttgct gctacatctg gaatatttcg tacacttgct
   161341 acaagggcgc aggtcattcc gataaaggtc atggtcgtga tttgctttga tgaaccagta
   161401 tctttcatct ttattccttc tttcaatagc gacatatgtt tttgttttct tttatttttg
   161461 ttcaagaaca gaaatgacaa ggtttcatcg attcagtaca aaacccagta tcaccgaaac
   161521 atccattgaa cgatcttagt gaactgggtt tgatacatga aacgaacgat ccaacttata
   161581 gaacgtttta taaaaaagaa tatcttggcg aggaatatat gaaaaacagg gggaaataca
   161641 attgttttga tgaagcaaat aattgtctgt tctccatatg tctcttgtta ttctttcaca
   161701 caaaaatcag ttctattgga tgatttcgtt tagtttcttt tccattgctt tggcgatttt
   161761 ttttgtataa aaattgaaaa ttcgatcatc attcaaataa ggagtcatga tagccgcacg
   161821 tagcagagtg attttctgtt cttttttcca ttcttctttc gttagaccca ttctttcaac
   161881 aaaacgaatc ggagaatcac cgtaatcttc ttgtgtaaat gtagtatgag aagtaataaa
   161941 ccgttcacca taaacatcgc catccatata agaagaccga tcgaacattt tttcatttaa
   162001 ttcattgata gcgttcaaat ctgtacagcc ttgttctttg aatacccaat tgaccatatt
   162061 aaaatcagga tgattcaatg gatagacttc gattgttttt cctttaacag taaaagtcag
   162121 atgatcgaga aattctctga atctttgagc tgcctcgatt gaagccccaa tcaattgacc
   162181 atatccggtc acattcaatg gcaatacacg atgtgctgtc cagactgcgg cggcggttgc
   162241 tccagctttt gatccttcca aaatataagc tcctaacata tctggagcct ttactgattt
   162301 ttcaaacaca tatggcgcga aataagaaat gatatttctc atatttttat gtttgattac
   162361 gattcctcca gcagcataag ggacatagcc catcttatga ggatctatcg tgacagaatc
   162421 cgcttctgaa atagctctga acccttcata tacctctttg tcaatcgtta cgcagtggtg
   162481 gaaaacatga tgttcttcaa agaattcagc taaggaagca tacggcacaa attctcctgc
   162541 ttcgtttaga aacagtgaac gcgcatagcc gccatatgcg gcatcaacat gtaaatagaa
   162601 atagatccct tcatctttta acctttctct taattggacg attttatcta cactgtctac
   162661 ttgaccttct tctgtcgttc ctacgacagc aaccacacct agaattggga ttttttgtcc
   162721 agctaattca cgaattgttt tttccaaagc attaatatcc attcgataat cctcttgaac
   162781 tgggatagca accatctgat ctaagccgac tccgcaaata tctaacgcct tcatccaaga
   162841 atagtgtttt gtttgaggga ccagccattt ccctaatctt tggatatttt ttccgctacg
   162901 ggaagaagct gctttgacct catccatttc ttcgtccgta aagctttcgg tcatttccaa
   162961 aatttcttca acagataaat tcaaaagttc ccactcagac atttttttca ctttttcagg
   163021 cagcacttcc ttgacagcta aaggaatcga tttgatgcaa cgggcgtacc ataatccttc
   163081 aagattagca atagaaccat ctgctgcaat gtgtccccat ccgtctgtca tattgaataa
   163141 tgaagcaaaa tcctgtccta cttctgcttc catttgcgaa gttgccatag aagattccaa
   163201 tgcaacatta tttgggttcc acagcatcgc atagttgtaa gctaataaag caggcatcaa
   163261 tgtttcagca ttcatttgtc cccagtaacg gcctgctgaa tgccatggga tcgatcctgc
   163321 gcgtaatcgc tgactgactt catccaagac ctctatcata tggtcgcggg tggctagata
   163381 atctggagtg agcttatctc cttcgctaat tgcaggcata tctgaaggaa tataattttc
   163441 tctccatcca agatgttcat ctaccatctt gttcaacaac attttataaa ctggtccatt
   163501 ttcagctttg tcgcctataa agacggcctt gatatccata tctttcattt ttcttccctc
   163561 catattttgt tggtcaatgt cttgcagata catgtgttta tctgtaacac ctcttcacta
   163621 tagcgccaaa aatgagaatt ttttttttat aacatcaaat ccacgtagat ttttacaaac
   163681 aaaaataaat aaagtcggat ttttctgata attcaacgca aaaaagcgaa caatttttca
   163741 ataaatcagt cttctaaaat agataaccta aaaaaagcga acaaacaaat aaaatgactg
   163801 tccttcattc actaaacata tttttatttt tttatattgt taaaaattcg caatttattt
   163861 tttaatagaa ttatctgttt tccaaatttt ataacataaa aaaccttttt taacggcatt
   163921 tatatgcttt ttcagaaatt aactgatgat ttcaaaaaga aaacatgtca taatatttcc
   163981 catattgtgc aaaaaaatac aaggcggagg ctctactatg attgaagaat atattgagaa
   164041 aaatatttta agacagctgt ttttatgtgg gcaattctat gtaaataaag aagtcaatct
   164101 agaaaagctc tccaatctcc tgcatgtttg caaaaccact ttactcaatg atatcaataa
   164161 cataaaaaaa gaatttgaag aacagatcgc ttatacacat cgggaaaagg accgttacac
   164221 tttatatttt tcagaacata tacctcgatg caagatcatg cagcaattgt ctcaaaattc
   164281 gttgttttta aaaacttgtc tgctttattt ggaagaagat gaacctgatt atcttcaatt
   164341 aactgaatgt gaattcatct ctgtcagcaa agcttattca ttaaaaaaac aagtattagc
   164401 ttattttaat gactgcggga tcgaaatcga ccgctactcc cctcgattca ctgaaatgga
   164461 aagacgtctg ctgcttctta atgtgtcgta tcgtttaggc ggttttaatt cttgggagct
   164521 acctgaatcg ttttttgaac gtgccgatcg tttcattgaa tccgtaacgg aaaatagtgg
   164581 cagattttat gataaagaaa ataaagaaat cttatcgatt ggttttgcta tcagtttcct
   164641 acgccagcaa gtgtgtgctg tgacaataga ttcaaaattt atcgaagaaa tcaaaaaacg
   164701 tcctatttac aattatgtcg aatcagcatg ggaaaacact gatttccaaa cctattataa
   164761 aaaagaagaa ttcgccttta ttttgacact attcaatctt tgtaattatg gtttccattc
   164821 ttatcagttg attgcggaag actttcaaca gctacaccaa gtgtttattg acaatactcc
   164881 cgaaataaaa gaactagttg ctacctttga atctcacttc aatcaagaat tattcggaaa
   164941 ccaaccgttc gaacgtgcgc tgattcatct gatgcgttcg gcttgggata actatcaatt
   165001 attcatgcca gaaaaatttt atcttttaaa tgaggaacag acaaatttat ataaagaagt
   165061 ccagacaatt ttttccagct ggtccagcca gttaccttat gatctacggt tgaatcctaa
   165121 ttgcatgcgg gcttttgtga tcgaattgag cggaattctc cgtctgacaa aagaacatct
   165181 gactatctat atcgtcacaa attcggatgt tcattatctg atttatcggg aagccttgga
   165241 agctgtaact actttcgatt ttcaagttgc accaacaatt tattcaagta tatctgatat
   165301 aaagaagtat gcgcagcagt cctcaaaccg ggtattatgt gaacgtacat tatatacacc
   165361 agatgcggtc caatatgaaa atattattcc tatttcgatc aatacgatcg atcgagctat
   165421 catttcagct gtgcaaaaca aataaggggc tgtgacaaaa atcatgtcac agcctcttat
   165481 ttgttgaaga tgcccatttc tgtaacaatc tcttgataca cgtcaggctc acaacctcac
   165541 ttattttgga catctacggg tccgatctct ttatttaaaa aataagaaat gatggttcgg
   165601 ataactacca acgccgctag ttggaaaata tcctgcaagg taggtttgat aatcgattcg
   165661 atgatcccag ctgaaacaag aatttccaaa cttagaagta tatagcctcc caacatcttt
   165721 ttaatagcat tgttctcgct gactcggtcg ctttgcactt ttgtatggac aaataaatat
   165781 ttcaaaaaat ccttgattga tagacaaaca ccccaaacca ataaacagat agcaaagata
   165841 tcaagtccca gtacaagttt ttcgaaatat ggaagaagaa actgcatcaa ctctgtcgtc
   165901 atcctacctc tcctcttctt tgtttttctt tgtcttctat ttcctgattc aagaaataag
   165961 aaatgactgt tcgaatgata ataataagtg caagcttcaa aatatctgtc caagtcggct
   166021 tgataactga ctcgatgata tcagcaacga ctagtacttc caagcttaac aaaatataac
   166081 ttgctagcag ttttcttgta tctgcattac gagtattacg ttctgcatag tttttcttga
   166141 catgagacca atcaaaaagt ttgaatagaa caagaacgat cccgacaatt aagataccga
   166201 tagaacaaat atttaaaata gcaatgatcc attctagaaa ttcaattaaa tttgagcgaa
   166261 acatatacgc tacctacttt cttttaattt gttcctattc ttttattgta aaagaaagtt
   166321 accttgttcg tctatttaaa agttgttcta atgataacgg ttcgcttaaa tttttctttt
   166381 tcactctccc atttttctcc ctccatccat aaatcgtgga agtatccaaa acaacgtagc
   166441 aagttaaaat aaggcttagt ccgtcatcag cttttcaaag aagcactgtc tcggtgcttt
   166501 ttttgtaccc aaatttctaa aaatagaacc atacacctcc tcaaatcttt tcttcttacc
   166561 taccctattt ttatttacag gaaaatcaga cacttcttct tttttgtcaa aatttccttt
   166621 ttcttctcgt cctatcattt ggcattctaa taaaaacgaa ctatccttgg atatagaaag
   166681 agaaaacaag gaggcgtttt tcatgagtaa aaaattaatc aaagtcggca tcggtttagg
   166741 tttgcttgcc cttggcgctg catatctagg aaaaaagaca ggactattcg aagatgacag
   166801 tcatttatat gatgaattcg aatcaatcta gcatcctatt tagttgaatc actacggaca
   166861 tacttggaag acattggagg aatcacaatg agaaaaagta aagcaataat gattggtgcc
   166921 ggtattgcca atatggcagc ggctgtttat ttgattcaag aaggcaaatg gaaaggggat
   166981 cagatcacct tttattcatt ggatgatcac ggttcaaatg atggtgcacc gaccgacact
   167041 gtagtggatg aatattggaa taaaaaccat ccattagaaa accaaaaagg ctatattgct
   167101 cgaggcggtc gcatgcttaa ttaccgtacc tatgtagatt tgatggatct gttaagtcga
   167161 ataccttctg ttactgagcc agggatgact gctgaagaag atacgagaga ttttgatgca
   167221 aaacaccgaa cctttgacaa agcacgtttg atggaaggtg gcaaaggaat cattgatggc
   167281 ggaaaactgg gattcaataa taaagaccgt attcttctga ctaaactgat tgctatgcct
   167341 gattcagaag aagaaaaact agacaatatc actatcgaag aatatttcaa agatgatcca
   167401 cacttttttg aaacaaactt ctggtttatg tgggaaacaa catttgcttt cagaacacgt
   167461 agttctgctc aagaattgcg tcgctatatg catcaaatga tttatgaatt cactcaaatc
   167521 gaacatctag tgggcgtcaa tcgaacacgt tacaatcaat acgaaagtat tatgcttcct
   167581 ttgatcgagt acttgaaaga acaaggatgc aaaatcattt tgaaccgccg tgtcactgac
   167641 tgggaattca aagaaacacc gatgcaagat gaaatcactg tgactggttt gaaaattacc
   167701 aatacactga ctcaagaaga agaatacgtt gtggtcgatg aagatacagc agttattttc
   167761 actaatgggt ccattacaga ttcagctact ttaggagatt acgaaacacc agctgtagaa
   167821 aatatggatt atggtgcagc ttctagtctc tggaaaaaag ccagtgaacg tttctacaac
   167881 ttgggaaatc ctgacaaatt ctttgctgat cgagatgcaa gcgaatgggt cagctttacc
   167941 ctgacgacga aaaaccattt gttgttgaat gaaatcaccc gtatcacgac tcaagaacca
   168001 ggaaatgcct tgaattcatt tatttcaacc acaccgatca cgccgttagg ccaaaaagat
   168061 gtcaatatgt ctatcgtcgt gcatcatcaa ccgcatttta cgtctcagaa accaaatgaa
   168121 acagttattt ggggttattt cctttatcca agacgacgtg gcgaatttgt ggataaacag
   168181 tatattaaaa tgaatggaaa agaaatgcta gaagaactga ttggacaact ttcaaaagta
   168241 gatcctggac cagtgaatat tcgtgaaaaa gaaacagaaa ttttcgacag cgtaataaat
   168301 aatatccctg tctatatgcc ttatgcttcc gcgttgttca ataatcgtgc caaaagcgat
   168361 cgaccaaaag tcattcctaa acattcgacc aatctggcct ttacaggaga atttgtcgag
   168421 cagccttatc agatgatctt tactgaacaa agtgctgtac gttctggaga aatcgctgct
   168481 ttccattttg cgggtattcc tatgtcccgt cttgtcaaaa caccgcgtta cgacaaagat
   168541 attcctactc tagctcgtgc cgcaaaaaaa atgtttgaat aatcaagagg ttgtgaaaaa
   168601 gctgccctgc atcaagtaat aagaacaacc aggctaaaac agcttcttat gtttttgatt
   168661 tggttggact tattaccgca gatgcaagct tttgaacacc gtttaccaag aggttgtgaa
   168721 aaagctgccc tgcatcaagt aataagaaca cccaagctaa aactgcttct tatgtttttg
   168781 acttggttgg acttattacc gcagatgcaa gcttttgaac accatttacc aagaggttat
   168841 gaaaaagctg ccctgcatca agtaataaga gcagccaagc taaaacagct tcttatgttt
   168901 ttgacttggt tagacttatt accgcagatg caagcttttg aacaccgttt accaagaggt
   168961 tatgaaaaag gcgtttagtt tcgagtatga agaaaaattt tgtgaaaatg gttcctcacg
   169021 tttttgcata aatttgactt aataccgaga aactgatccc ttctgtcata acctcttttt
   169081 atttatgtct gtttcttttt gaaaacaact attttttcaa cgtttactct cttgccaatc
   169141 caacatcatc taacggatac aactatttca atgattacca ttacactaaa aaatcggaaa
   169201 cacacctctc cgaacacaaa tacataagac tatagaatgt ttcatttaag aaaaaaagcg
   169261 tttcattatc aaaaaggtaa gatctccttt aaaatgaaat tatctgtagt actaataatg
   169321 cagacaattt tatgaatctg aaaggagcat ctccaatgaa agcagtcact tggcaaggaa
   169381 aacagaaaat ggaaatcaga aacgtagatg atccaaaaat attagaacca acagatgcaa
   169441 tcatccgtat cacagcaaca gccatttgcg gctccgatct gcatctttac catcatggtg
   169501 aagcagtttt ggaaaaaggg tatgttgtag gacacgaacc aatgggaatc gttgaagaag
   169561 tgggatctca agttcaaaca ttgaaaaaag ggcaacgtgt ggttatccct tttaatatta
   169621 gttgtggtca ttgtcatttc tgcctgaatc acatggaaag ccaatgtgat gaatcaaatc
   169681 cagatcagtt atatggcggg cttttcggat ttggcaagtt gaacggtaat cattggggtg
   169741 gtcaagcgga atatctaaga gttccttatg cagactctac ttcatttgtt gtaccagata
   169801 atgatcttcc tgatgaaaaa gttttatttc tatcagatat tttgcccaca gcttattgga
   169861 gcgttgaaaa cgcaggagta aaaaaaggcg atacagttgt gattctaggt tctggtccag
   169921 tcggtctatt cgctcaaaaa ttcgctgtta tggctggagc agagcgcgta atcgcagtag
   169981 atccagtaca gcaccgtcta gataaagcgg ctaattacaa tggggttgaa acttatttct
   170041 tagaagacac ggcacaagct ggaacagaat tgtatgaact ggctaaaggt ggcgcagatg
   170101 tcattatcga ttgtgtagga atggacggat tagagcctgt caaagaaaaa gcgaaaaatt
   170161 tagtaagctt acaaagcggc acaatctctc cattacagat ggcatcgcaa gctgtcaaaa
   170221 aatttggaac agtccaagta actggtgttt atatgactcc agcttcttct tacccgctgc
   170281 aagaattttt tatgcgggat atcgctgtca agcatggaca ggcaccaatt atccatctaa
   170341 tgccaaaaat ttacgcaatg attgcagaag gactattcga tcctacacaa atcattactc
   170401 attcgctgcc actatcagaa gcagcacaag catatgagat ctttgacaaa aaagaagata
   170461 aaaatataaa agttgttttg aaaccttgaa ttcagtaaaa aatacaggtg attttcttta
   170521 tgcccaaaat caaacgaaat acccatgaga tcgaaatagg aaaagaagaa gatatcgaaa
   170581 tacgaggacg tcgcttccgc ttctatttcc aaaatcgtta cacattgatc tcactggctg
   170641 tcgatttatt aaccgggatt ttctatattt ttggaagcct tgcttcctta actaaaatcc
   170701 ccgatcgata tggcacctat ttttatttgg ctggtgctat tttcttgacg attcgtccta
   170761 ttctcagaat cgtaaggaac atttttattt acgacgaaaa aaaagcaatg aagagaacaa
   170821 gcaaaaaaaa agaggcatga gaatttttca aatctcatgc ctcttttttc accctatcgt
   170881 atcactttga tacagacgag cggtcgtccc actttcttcc ttgaccattg tcaaaaatgt
   170941 ccactcgtat cgttcataaa acgtggtatg atctgtaatt aagtaaagtt tttcgtaccc
   171001 aagttgatgc atttcttttc tgatttccgc taatatccgc ttggctatcc cctgcttacg
   171061 cttttccggt tcaacaaaca gggcacaaag atttggtgtc agatcagggc ggttatggaa
   171121 gtcgttttca atgacgcccg ctcctccgac gatggtttct ttttcatcta agaccacata
   171181 ccattgagga atactttcct tattagcgat tccagtacga atactttcct catacacaac
   171241 agcaggaact ccccattttg atgaaaacca attcgcgctt tgttttacta attctgggtg
   171301 ttctcttaat ttgatccagt tatatgtaac caatgtttaa acctccgact aaaataaaac
   171361 gtttacaaaa attatacaag tctttatgaa aattagcaat gacaacaata gtgatgtaaa
   171421 aaaaaaaacg gaaaacaatc acttgttctc cgttttttga ttgatcaagc atctaaagct
   171481 tcttttcttc tttcttggat cgtagctacc ttgacgaacg gtagatagat caaaatagaa
   171541 agaaccaaat tgacagcggc tagtacacca cctgcaatac tttttgttgc caatacaccg
   171601 ccaataattg gtggagttac ccatggaggc ataacggtag ctgctggcac taaacctgta
   171661 gaagtcgcaa agtaagcaac actaactaag accattggtg tcaaaataaa tggaatgaac
   171721 atgatcgggt tcaacacgat aggtaaccca aacatcgttg gttcattaat attgaaggac
   171781 acctggcgca atcgacaagt ttgttacaac catatatggt ttgtttttac gtcctactaa
   171841 ataaatagct aacagtaaac ctaaagttgc acctgttcct cctaagttga caaagctgtc
   171901 aaagaaaggt ttgttcacga taaacggtgc gctatgccca gctgcgattg cattaacgtt
   171961 tgcttcaatg gctggcgcat tgattgtttg catcaaagga tcgaccatat tcgctccgtg
   172021 taaaccaaag aaccataaga atggtgtgat aaatgcaagc agtaaggcag atggataaga
   172081 gtttgcaagt cccataaatg gttcttggac cactgtatag aaagaaccta cgatatcatc
   172141 aacaccgaat gcagcaaaaa ttgcagcaac taaagcaaac gcagagatag tgatcattgc
   172201 tggtagtaat gaagcaaatg cttttgcaac tgccggtggc acaccatcag gcattttgat
   172261 gatcaatttt tcatttccgc ttaaacgtac aaagatttct gttgaaataa tcccaacaat
   172321 aatagcaata aacaaaccgt ttgagctcat acctaatgct ccgcctaaag cgaagaaaga
   172381 gcctaaagaa atcacacctg cggaaacacc gtcttttcgg tagccgttag ctaaatgata
   172441 agcaagcaag aaagcaatca agacagaaag aatggcaaat gtaccgttcc aagcagcagc
   172501 cccgaatcct ttccatgatt caccaccaaa aattgagttc atcaattctt ggaacccggg
   172561 aatcggtaag ttattgatca ttactgctaa tgctcctaag atcattaacg gcatactcac
   172621 cataaatgag tcccgaatcg caactaaatg ccgttgtgca ccaatttttg atgctacagg
   172681 tataaaatgt ttctccataa atgcaacaaa tttatccata aatcttccct cttttcttta
   172741 ctgtagatta cgcgttcaat cgacgataca gatcaatgat ctcttttgct aaatctgtaa
   172801 aagctataga tgtcatcaga tgatcttgac tgtggaccgt caaaagcgtg acttcaacgt
   172861 gatttccttg tgcttcttgt gtcagcatct ctgtttgaga gtgatgtgct tggactaaag
   172921 attcctctgc atctttgatt ttttcatctg ctaaagtgaa atcacctttt ttcgcagcag
   172981 caatcgcttc cattgcatcg ctttttgcat ttccgccaaa catgatcaga cccatgatgg
   173041 cttctagatt tttttgatct tccatttatt gtatcctccg ataattttta ttatttgttt
   173101 attagttttt ctgcttggtc gagtactttt tcaccattca tcatgccata gtcagccata
   173161 ttgattacat ctaaaggaat gcctttaggt gctagctttt cagcaaattg attttgcata
   173221 aagcgtactt gcggtcctaa aagtaaaacg tctacatttt tagattctag ttgattatcc
   173281 gcatctgaag cagatacagc aaagatgtct gcttccattc cttttgcttc tgctgccttt
   173341 tgcatttttg tgactaggag acttgtactc attccagctg aacatacaag catgattgtt
   173401 ttcttttcca ttttaaacac gttcctttct atacttacac ttgtatataa gcaagtagcg
   173461 tgccaacttt aaaagcgctt taaaaagttg atatcatcac atttaaggtc tataccaagt
   173521 tgcatacaca ctaaaaaaga aagcgcacac taaacacaca aattaatttt tattaccttt
   173581 tttcttttaa cgtgcacaaa aaaagttgtg acacaaaact tgtcacaact tttttcaaat
   173641 aaacggtatt caaaagcttg catctgcggt aataagtcca accaagttaa aaacataaga
   173701 tgttgttttt actttgctat tcttattact tgatgcagga cagctttttc acaacctctc
   173761 aataaacggt gttcaatcag ctgaccctgg gtattagctc aaaacgctgg attcacaacc
   173821 tcttttattt caaataacca gtaaatacaa tgaacatcta caaaaaactt ctatttattt
   173881 atagatttcg tcaggcaaat ccaattctct cttatcaatc aaagtctgat accacgaagc
   173941 agattttttc aatgttctgc ttcgttcatc gttcaattcg attcgaacta atccatatcg
   174001 attcttaaat gcattcattg gtgacacaca gtcagtgaat gcccataaca tatagccttc
   174061 gcaatttgcg ccttcttctg ttgctttgat caagtaatgc aaatgctgtc cgataaattc
   174121 gatacggtaa tcatcttgca cgattccttt ctcatccata tactgttctt catattctct
   174181 tcccataccg ttttctgtta tcagccaagg gatattatga taattttctt ttagatacat
   174241 ggctatatca tacatgattt tcggatagat ttcccatccc ctggaattat tcattttctt
   174301 cccaggtaaa tcaaagactt cataatatcg ttcaggatgg aaaggtgtct cttcattcca
   174361 ttgataacga ggggcgcgaa cgcgtttagg ataatattga ttgattccaa ggaaatctac
   174421 tgtatgatgc tgaatcgttt ctaaatcctc tgttgcagga tcgaaataaa tcgattgttt
   174481 ttgacacaac tccaggaact cttctgtgta gtatcctttt accatcggat caaaaaatac
   174541 tcgattataa aacaaatcat acatataagc agctttttgg tcttctggag aattggatcg
   174601 agcatagacc atttcaggat ttaaaataca gccaatcctt ccaccataat ttccgctgcg
   174661 gtaaatctct actgctttag ccgttgctaa aactttatga taattccaca tcatccactt
   174721 ttttgtgttt tgttcatgcg gccagcgaac agcatccaaa tagcaacgcg tttggggaac
   174781 gattggttcg ttgaatgtaa accagttttt taccctatca ccgtaacgat caaaggcaat
   174841 ttgagcatac ttagcataaa aatcaactac ttttcttgaa gaccagccat catatttttc
   174901 caaaagaaaa gctgggactt cataatgttc caaacaaatc atcggttcta cgtctgcttc
   174961 gatcaaagag tcgatcattt cacttatatg ctgagcatat tcttcatcta ctatacagtt
   175021 ctcataatca gtaaaaaaac gagcccaatt gatagaagtc cgataatgtg tcagatggat
   175081 ggatttcatc agatccacat cctgctggta ttgttccata aaattagttg ctacggctgg
   175141 gccataccca ttatgccaaa caaaatgttc atttttatac cagctatcta taaacgaatc
   175201 ctgtccttct ttttttcctt tccaaccttc cgtttgccaa gcagaagatg cagcaccaag
   175261 aataaaattt tttggaatag taattttcat gatttcctcc tgttttttag atcccatcat
   175321 tttccacacg atttgctact tttacaaatg gcagatagat caaaatagaa acaataatac
   175381 aaacaagttg cgtaataact gcaccgatat ttcctgctgt tgccagataa gcattgacga
   175441 tcggcggcat tggccaaggg accattacaa ctgctttcgc cgcaaatcct aaagcggttg
   175501 caaaataacc aatcgttcca gtgataagag gcgttaagat aaacggaata gctaaaattg
   175561 gattcagcat gatcggcata ccaaaaataa ctggttcatt gatgttgaag atcccaggag
   175621 caagggataa cttggtgatt tgtttcatat cttcccgttt tccaactaac aatactgcaa
   175681 tcagtaaacc gatcgtgact ccagacccgc ccatactcat atacatatcc caaaatggca
   175741 tagtaataat gttcggtact tcttttccag cttcaaaagc ttccgtattt acagcaattg
   175801 ccgctaaaag caacggttcc cgtatcggct tcaccatttg atttccatgg ataccaatca
   175861 cccaaaagac ttgcgcaata aacatcaata gcaaaatacc cggtaaccct tgtacgacac
   175921 cttctaatgg gcgttgtacg acattgtaaa tgatatcata aaggtacatt cctgtaagtt
   175981 ctttgatgat aaatcccgca gccgcgatac ccgatacagt cagaatcgtc gggaataaag
   176041 cagaaaaact agcagaaaca ttcgttggca cggtatcagg cattctcagc tgtagtttct
   176101 tctgtttcct caaccagcaa taaagttcaa tagaaaggat ggagaccaac attcccaaaa
   176161 ataacccttt cgtatctgta tattgtttag ccaatacgtt ttctactata acagtctgat
   176221 tttcattcac taattcataa acagttggat taacagataa ataagacatc actgcgatga
   176281 taccagggaa tacaccatcc actttattca gcttggctaa ttcgatccct atcagaaaaa
   176341 cagcatagat ggtcaagaaa cttagtgtga catagctgat ggcagatgcg ataggcttta
   176401 attcttctaa aaaacgcaag aaacttatct gtgctaagcc attttccgag tcaaagacca
   176461 ttgctgaaaa caatgtgcca aaagcacccg taataattac cggaatcaat gcagcaaatg
   176521 cgttttttat caccatgata taccttaaat tattgattct cgttgccacg ttccctaaaa
   176581 cattggctaa tttatccata aaactcattc cagatcccct cattcctgct tcttctcctt
   176641 gacgtcatct ctttttgtct attagtcagc gcttacattt cgatgaacag aaactattta
   176701 ctcctctttt ttaccaaata taaaacaaaa attcatctga tgtatttatc ataaaataca
   176761 tcagatgaac tgtcaattag tttctttttc tcctattatt ttctgtaatt ctctccgatt
   176821 tattgccata tggacagtca ttgcatcaaa cgcagcaagt gcattccgcc tttcgatggc
   176881 ctgaacgatc tctgtatgaa tatcgatcgt ctcgattttc agatgctgga tatcataatt
   176941 tttattaaac aaagcaattg attcattaat gattgggata atatgcagca aggctacgtt
   177001 tccgctagct tctgcaatca tcgtatgaaa atcgatgtct aattgaacat gttcttgtgt
   177061 gccttctcga aaagaagttt caatcttttg cgttaatttt ttcatttgga cgatttgatt
   177121 cttcgttgca tattccgctg ccaaacctgc catcttaggc tccaataaat atctcagttc
   177181 aaataagtct cgtatcatcc gatcctgatc ttcaatcaaa gaaaaaccga gtgggtcatt
   177241 ggcaatccct cgcttatcac tgacaaatgt ccccgctcct tgccgaactt caaggatatt
   177301 cctggaagct agagcccgca cagcttctcg caccgtgctt cgccccacct ctaaataatc
   177361 ggacaattca tattcattcg gcagtttatc tcctacttgc aactgcattt cctttaaata
   177421 tctaaggatc ttgtcagtag ttacttctac tagggtttta ttttcttcca aaccacatac
   177481 ctccttttca tctgatgtat tttttcgtaa ttattataac acgtttgaat catctgatga
   177541 ttttttgtat acaaaattga ttaatccgtt catagacata caaacgaaga agatatttac
   177601 cataaaaaag actaggataa aattcactcc tagccttcga tcatttttat tttgaacgac
   177661 aaaaaatatg atgttcaata acagacgatc ttcattcgat tcttgatgtc atcttttgtt
   177721 ttttttaata tatggataaa aagtttgatt acatcgtttc tattctagaa tttggtcgat
   177781 tctcaattct tcttctggtg agaaatctaa attatccatc attcgaacac tttcttgtaa
   177841 ctgacttaac cgacttgctc cgaccagtac acttgtaaca gatttttgtc gcaaattcca
   177901 tgcaagggcc atttgcgcta atgattgtcc tcgtgatacg gcgattgttt gcagtgcttt
   177961 gattttttcc agagttgatc caacttgttc ttctgaaagg aatggtattt ccttacgatg
   178021 tgctctagaa tcttcaggaa taccatgtag ataacgattt gtcagcaacc cttgagcaag
   178081 cggactgaac gtgattgccc ctagcccttc ttcttctaat actggagata gatcgtcttc
   178141 tagtagtgca cgagaaaaca tattgtagcg catctgatga ataatgaacg gtgcttcctt
   178201 tctttttaaa atttcagtca ttttttttgt atcttctcca ttatagttgg atataccaat
   178261 atataatgct tttccttgtc ttacaagttg catcaaagct tctgctgttt cttccaaagg
   178321 tgtatcaggg tctgggcgat gatgatagaa gatgtcaaca taatctagcc ccattctttg
   178381 gagactttgg tcacaacttg aaatgatgga tttacgagag ccccattccc catatggccc
   178441 ttcccacata tgataacctg ctttgctaga aataatcagt tcatcacggt aggcttgaaa
   178501 atcttctcta aaaatacgcc caaagttttt ctctgcagct ccagcagggc ctccataatt
   178561 attcgcaagg tcgaaatggg taattcccat gtcgaatgcg cctcttaaaa tctctctttg
   178621 attatggata ggatcataat caccaaaatt ttgccataat ccgagagata aaatcggtaa
   178681 tttcaaacct gaatgaccgg atttacgata ttccattttt tcataacgtg cactatctgc
   178741 aatatacaat ttttctcctc ctcatcaaat ctttttaaaa cgctttcttt tttctatttt
   178801 tagtttacta cattttaaag aaaaggagtt aatcaaaatg attttttcgt atattttttt
   178861 gccatttgtt ttttactcgt tgatagatca gaaattgatt acgtgcttgc tggatttttt
   178921 tataacgttt cggttgtttt ttgtaaaatt gctgatgata gttttctgct ggccaaaacg
   178981 taccggctgg ttcgattttt gtgacgattg gttggtggaa agttcctgaa ctgtctagtt
   179041 tctgttttga ttgttccgct aattcttttt gtcgttcgcc ttgataaaaa atcactggac
   179101 gatattgctt ccctctatct tgaaattgtc caaatgtatc tgtgggatca gtaatttgcc
   179161 aatagattgt cagcaactcg ctataactta tttctcttgt gtcataaatg atctccacag
   179221 cttccacatg acctgtgtaa ccaccactta cttgatcata atttggtttt tcaacatgtc
   179281 cgcccgtgta tcctgacaaa acagatagga tccctttttt cgattcaaac ggctcgacca
   179341 tacaccagaa acatccccct gcaaatactg cacgttcttg atagtcagca tcttgcatgg
   179401 catgcttgga aaagtcatat ttttgctcct tatcaaatcc ttccgtaatc aataaataaa
   179461 agtccattac atcaggcgtc agattcattc ggatagctaa tggacgtagt gttgcttcta
   179521 gttttgataa ctgttcttta acggatatat tttctcttat gtcattcttt gtctgaatca
   179581 atacttttcg ttcccaatct cgtgtattcg gattcaaaat cagattataa agtgtttgaa
   179641 tgaatatttg ttcctcatcc atagattctc ctcctttccg aagaagacaa gctagtgact
   179701 ttagctgtaa tttatcataa agtgaggaaa taagcgatta cttcatcccc ctacagattt
   179761 ttcgtataaa aaagagagaa tccttatcga cagattctcc tttttaatca atttatttta
   179821 taaatgaaaa gttaatttac cttttatgga aaactatttt aaaaaataaa cataaatatg
   179881 cagttaatgt aacaagataa gaaataatag tcgttactgt ataacttgtg cttactttaa
   179941 tatcagcaac tcctttgact ccgcttattt gtaccaatcc attagcattc acctgctcct
   180001 ttacaggttg atgatttatt tctacattcg ttcctaaata agcatataca ggaagtgtga
   180061 ttacttggct cttctcatta gttactctat atatgataga actaccagtt gttttataag
   180121 gaaggtttac ccattgactg ccaatctttg cttcgtgttt tattatatgc tccttattct
   180181 ccaatgaagc gataggagaa taatcatata aaaaataatc cattccttta gtggtatacg
   180241 cctctactgt ttctttgttt acaacaatat gtcccggctg agaaattatt ttttgattga
   180301 aatttttttt actagaaaca gttaaagtga ttaataacaa aacagtcata aataaataaa
   180361 atagttctct tgtcttattg tatcttctat ttttgaaaaa tatcatcgtt aatatcagag
   180421 aagagaatat tatttgcaag cttaagatcc gccaaggaaa ttgtaacaat ttggctggcg
   180481 tattttgcag aagataccat ggcaccaaac tagttgtagc tagccaagtc aaacacgtac
   180541 cataataaat ctttttttct atgtttgtta attttttaaa taaaatcagg ggaatacata
   180601 aagataacag accaactagt cccattgagt aagtagttaa gtcgttgttc atagcttcag
   180661 tcagactatc gaacacatta gatgcatgag catataaatt tgtcacgcta ggtttgttga
   180721 ttttttggta gagcatttgt tcaaacatcg gataccaaaa agcactcgtc agaaccaatg
   180781 tcattcctgc cgcactaaat aattttttaa atatagcaat aaaatctgca ttcttgaaac
   180841 ctttagaaac caaacgaata aaaatgataa ttaatgctgt actcattaat gttgatagta
   180901 catggctgta cactagcaaa ctcatactca atgctagctt tacagacgga tacttttctt
   180961 cttttccaga gatgatttga taagcataaa ataatacagg gataacaagt gttattgcga
   181021 tagcttcggc aattgcggaa cgatagtaga tgtctactgt ccgataagca gagaaaatat
   181081 agagacaact aaataaaaat gccgcttttt tttgttttaa aaaccgctcg ccataatgat
   181141 aagctacgag tgttgtacac aagttcaata accaaacgta aataatatag cttacaatca
   181201 aattttttgt catccaatat aacattacag ctggaaaaaa agtcagaaag ggataaaaat
   181261 aatttacacc atatccagta taattgaatg tctcataatt aatcggactg gtaaaaatag
   181321 tcgataaccc cttgattcga gataagtgaa aagaaagatc tccagtggta taaatactct
   181381 gtgtattttt gaaaaagatg aaagaatata tactactaac tataattaat ccactcaata
   181441 ttactacttt tttatttatt ttcattcttc ttgtttatct cctttttagt cacatatcga
   181501 gaatctttca acttattagg tgcaaatcgt ttaaaacttg aatacaccac taaacaataa
   181561 gtcagaatac tgatccataa agccatgaga gcagttggag tatattttgt tgtaatttct
   181621 atcttatttt ctccagcatt tacatccaca ttcactaagc catgtttttt ataagagtca
   181681 tttacgactt taccgtttac ttttacctgt gtacctaaat aagcatatac tggtactgtc
   181741 actttttgct ttttgttgct tgccactgtg taagtaatgt tattatctgc agctttatac
   181801 ttcccttttt cccacgattc tcctactttt acttcatgtt tttctaagtg aggcctttct
   181861 tttatcgctt ctgttggggc gtaatcgtat aatcctccca tatctgatgt tgtataacgt
   181921 gggagtgttt cttcattgat aacaatatga ccgtgttttg attggataac ttttgcgtaa
   181981 ttttcttttg ctgctataga cgtgacgagt agaaacacca cagtagcgcc aatgattaac
   182041 catgaatatt ttttattcat agtctttttc ataaaaacaa gcgttatgat cattgaagaa
   182101 aaaaagattt ggatacctaa gatacgccaa ggaaactgga gcaagcttat cggtgttttt
   182161 tgaaacaaaa accatggaaa taaattagtt acgcataccc atgtagaaac tacgccaaca
   182221 tagatgattt tttctttttt ctccatttct ttcagtatga ataaaggaaa aatcaacgca
   182281 accaatccta ataaccccat agtgtatgtt gtaatatcgt tatttaacgc ttgaatgata
   182341 ctatctgaaa tagaaagtgc ttctagctgc aaatctgttt tgaagggact gtgtatttct
   182401 tgataattca tctgctgcaa cataggatac caaaaatagc tagttaatgc acaagtcaaa
   182461 aaaacagcct ttactaaatt cacgaccaca aattttatat cgttttttat ttgcttgctt
   182521 aaaaacaaac gaactataat catacaagca atcaatgcac tacacaatag tgtagttaag
   182581 acatgagtat acacaagtag acttatactg acagataaag cgatgacttt tttttctcta
   182641 ttgaatatca atccataagc ataatataaa acagctggga taatcgtaag agcgattgct
   182701 tctgcaattg cggatcgata atagatatca actgttcgat aagttgcaaa agtatataaa
   182761 caactaaata aaaaagcagc atctatcttt ttaaaaaact tttctccata ataaaaac
//
LOCUS       DARPZF010000002       133088 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.002, whole genome shotgun sequence.
ACCESSION   DARPZF010000002 DARPZF010000000
VERSION     DARPZF010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 133088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 133088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..133088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.002"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            598..1287
                     /locus_tag="SLE65_000167"
     CDS             598..1287
                     /locus_tag="SLE65_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8447493.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1274..2482
                     /locus_tag="SLE65_000168"
     CDS             1274..2482
                     /locus_tag="SLE65_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEI8447494.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2776..4047
                     /gene="serS"
                     /locus_tag="SLE65_000169"
     CDS             2776..4047
                     /gene="serS"
                     /locus_tag="SLE65_000169"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEI8447495.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="SLE65_000170"
     CDS             complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="SLE65_000170"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEI8447496.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6585..7280)
                     /locus_tag="SLE65_000171"
     CDS             complement(6585..7280)
                     /locus_tag="SLE65_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEI8447497.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="SLE65_000172"
     CDS             complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="SLE65_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEI8447498.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8479..8670)
                     /locus_tag="SLE65_000173"
     CDS             complement(8479..8670)
                     /locus_tag="SLE65_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HEI8447499.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8691..9581)
                     /locus_tag="SLE65_000174"
     CDS             complement(8691..9581)
                     /locus_tag="SLE65_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEI8447500.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9568..10335)
                     /locus_tag="SLE65_000175"
     CDS             complement(9568..10335)
                     /locus_tag="SLE65_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEI8447501.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="SLE65_000176"
     CDS             complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="SLE65_000176"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEI8447502.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="SLE65_000177"
     CDS             complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="SLE65_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEI8447503.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="SLE65_000178"
     CDS             complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="SLE65_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEI8447504.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14906..15289
                     /locus_tag="SLE65_000179"
     CDS             14906..15289
                     /locus_tag="SLE65_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447505.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15457..16215)
                     /locus_tag="SLE65_000180"
     CDS             complement(15457..16215)
                     /locus_tag="SLE65_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HEI8447506.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16233..17051)
                     /locus_tag="SLE65_000181"
     CDS             complement(16233..17051)
                     /locus_tag="SLE65_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEI8447507.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="SLE65_000182"
     CDS             complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="SLE65_000182"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEI8447508.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="SLE65_000183"
     CDS             complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="SLE65_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEI8447509.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18179..19513
                     /gene="dnaA"
                     /locus_tag="SLE65_000184"
     CDS             18179..19513
                     /gene="dnaA"
                     /locus_tag="SLE65_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEI8447510.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19711..20841
                     /gene="dnaN"
                     /locus_tag="SLE65_000185"
     CDS             19711..20841
                     /gene="dnaN"
                     /locus_tag="SLE65_000185"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEI8447511.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21070..21312
                     /gene="yaaA"
                     /locus_tag="SLE65_000186"
     CDS             21070..21312
                     /gene="yaaA"
                     /locus_tag="SLE65_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEI8447512.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21299..22423
                     /gene="recF"
                     /locus_tag="SLE65_000187"
     CDS             21299..22423
                     /gene="recF"
                     /locus_tag="SLE65_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEI8447513.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22420..24366
                     /gene="gyrB"
                     /locus_tag="SLE65_000188"
     CDS             22420..24366
                     /gene="gyrB"
                     /locus_tag="SLE65_000188"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEI8447514.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24386..26857
                     /gene="gyrA"
                     /locus_tag="SLE65_000189"
     CDS             24386..26857
                     /gene="gyrA"
                     /locus_tag="SLE65_000189"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEI8447515.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27093..27392
                     /locus_tag="SLE65_000190"
     CDS             27093..27392
                     /locus_tag="SLE65_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEI8447516.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27442..27954
                     /gene="ssb"
                     /locus_tag="SLE65_000191"
     CDS             27442..27954
                     /gene="ssb"
                     /locus_tag="SLE65_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEI8447517.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27980..28216
                     /locus_tag="SLE65_000192"
     CDS             27980..28216
                     /locus_tag="SLE65_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEI8447518.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28359..30332
                     /locus_tag="SLE65_000193"
     CDS             28359..30332
                     /locus_tag="SLE65_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEI8447519.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30338..30790
                     /gene="rplI"
                     /locus_tag="SLE65_000194"
     CDS             30338..30790
                     /gene="rplI"
                     /locus_tag="SLE65_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEI8447520.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31064..32431
                     /gene="dnaB"
                     /locus_tag="SLE65_000195"
     CDS             31064..32431
                     /gene="dnaB"
                     /locus_tag="SLE65_000195"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEI8447521.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33211..34503
                     /locus_tag="SLE65_000196"
     CDS             33211..34503
                     /locus_tag="SLE65_000196"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEI8447522.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35239..36102
                     /locus_tag="SLE65_000197"
     CDS             35239..36102
                     /locus_tag="SLE65_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEI8447523.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36231..37853)
                     /locus_tag="SLE65_000198"
     CDS             complement(36231..37853)
                     /locus_tag="SLE65_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8447524.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38102..38623
                     /locus_tag="SLE65_000199"
     CDS             38102..38623
                     /locus_tag="SLE65_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HEI8447525.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38809..40539)
                     /gene="spxB"
                     /locus_tag="SLE65_000200"
     CDS             complement(38809..40539)
                     /gene="spxB"
                     /locus_tag="SLE65_000200"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEI8447526.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40704..41522
                     /locus_tag="SLE65_000201"
     CDS             40704..41522
                     /locus_tag="SLE65_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HEI8447527.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41625..41822)
                     /locus_tag="SLE65_000202"
     CDS             complement(41625..41822)
                     /locus_tag="SLE65_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447528.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            41991..42569
                     /locus_tag="SLE65_000203"
     CDS             41991..42569
                     /locus_tag="SLE65_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HEI8447529.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42664..42801
                     /locus_tag="SLE65_000204"
     CDS             42664..42801
                     /locus_tag="SLE65_000204"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447530.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(43614..44117)
                     /locus_tag="SLE65_000205"
     CDS             complement(43614..44117)
                     /locus_tag="SLE65_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEI8447531.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44476..45501
                     /locus_tag="SLE65_000206"
     CDS             44476..45501
                     /locus_tag="SLE65_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEI8447532.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            45848..46726
                     /locus_tag="SLE65_000207"
     CDS             45848..46726
                     /locus_tag="SLE65_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HEI8447533.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            47202..47318
                     /locus_tag="SLE65_000208"
     CDS             47202..47318
                     /locus_tag="SLE65_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEI8447534.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            48246..48584
                     /locus_tag="SLE65_000209"
     CDS             48246..48584
                     /locus_tag="SLE65_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447535.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            48678..48908
                     /locus_tag="SLE65_000210"
     CDS             48678..48908
                     /locus_tag="SLE65_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447536.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            49308..49679
                     /locus_tag="SLE65_000211"
     CDS             49308..49679
                     /locus_tag="SLE65_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HEI8447537.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(49953..50645)
                     /locus_tag="SLE65_000212"
     CDS             complement(49953..50645)
                     /locus_tag="SLE65_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEI8447538.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(50648..51433)
                     /locus_tag="SLE65_000213"
     CDS             complement(50648..51433)
                     /locus_tag="SLE65_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEI8447539.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            51670..53070
                     /gene="lacG"
                     /locus_tag="SLE65_000214"
     CDS             51670..53070
                     /gene="lacG"
                     /locus_tag="SLE65_000214"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEI8447540.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            53095..53412
                     /locus_tag="SLE65_000215"
     CDS             53095..53412
                     /locus_tag="SLE65_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEI8447541.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            53425..55098
                     /locus_tag="SLE65_000216"
     CDS             53425..55098
                     /locus_tag="SLE65_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HEI8447542.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            55112..56743
                     /locus_tag="SLE65_000217"
     CDS             55112..56743
                     /locus_tag="SLE65_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HEI8447543.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            57615..58805
                     /locus_tag="SLE65_000218"
     CDS             57615..58805
                     /locus_tag="SLE65_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HEI8447544.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            58939..61128
                     /locus_tag="SLE65_000219"
     CDS             58939..61128
                     /locus_tag="SLE65_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEI8447545.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            61125..62918
                     /locus_tag="SLE65_000220"
     CDS             61125..62918
                     /locus_tag="SLE65_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HEI8447546.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            63118..63432
                     /locus_tag="SLE65_000221"
     CDS             63118..63432
                     /locus_tag="SLE65_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEI8447547.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            63453..63830
                     /locus_tag="SLE65_000222"
     CDS             63453..63830
                     /locus_tag="SLE65_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEI8447548.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            63840..64613
                     /locus_tag="SLE65_000223"
     CDS             63840..64613
                     /locus_tag="SLE65_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447549.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            64635..66038
                     /locus_tag="SLE65_000224"
     CDS             64635..66038
                     /locus_tag="SLE65_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEI8447550.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            66220..67404
                     /locus_tag="SLE65_000225"
     CDS             66220..67404
                     /locus_tag="SLE65_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEI8447551.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            67401..67691
                     /locus_tag="SLE65_000226"
     CDS             67401..67691
                     /locus_tag="SLE65_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447552.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            67688..67909
                     /locus_tag="SLE65_000227"
     CDS             67688..67909
                     /locus_tag="SLE65_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447553.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            67951..68730
                     /locus_tag="SLE65_000228"
     CDS             67951..68730
                     /locus_tag="SLE65_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HEI8447554.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            68797..69291
                     /locus_tag="SLE65_000229"
     CDS             68797..69291
                     /locus_tag="SLE65_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEI8447555.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            69347..69985
                     /locus_tag="SLE65_000230"
     CDS             69347..69985
                     /locus_tag="SLE65_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447556.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            70057..70452
                     /locus_tag="SLE65_000231"
     CDS             70057..70452
                     /locus_tag="SLE65_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEI8447557.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            70436..72889
                     /locus_tag="SLE65_000232"
     CDS             70436..72889
                     /locus_tag="SLE65_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEI8447558.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            72886..74913
                     /locus_tag="SLE65_000233"
     CDS             72886..74913
                     /locus_tag="SLE65_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447559.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            74910..75932
                     /locus_tag="SLE65_000234"
     CDS             74910..75932
                     /locus_tag="SLE65_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEI8447560.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDGETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            75949..76878
                     /locus_tag="SLE65_000235"
     CDS             75949..76878
                     /locus_tag="SLE65_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEI8447561.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            77123..77239
                     /locus_tag="SLE65_000236"
     CDS             77123..77239
                     /locus_tag="SLE65_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEI8447562.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            77255..79174
                     /gene="tet(M)"
                     /locus_tag="SLE65_000237"
     CDS             77255..79174
                     /gene="tet(M)"
                     /locus_tag="SLE65_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEI8447563.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIV
                     NTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRL
                     NSRIDKVRYMFNKIT"
     gene            79272..79460
                     /locus_tag="SLE65_000238"
     CDS             79272..79460
                     /locus_tag="SLE65_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEI8447564.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(79518..79871)
                     /locus_tag="SLE65_000239"
     CDS             complement(79518..79871)
                     /locus_tag="SLE65_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8447565.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            80402..80824
                     /locus_tag="SLE65_000240"
     CDS             80402..80824
                     /locus_tag="SLE65_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEI8447566.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            80821..81051
                     /locus_tag="SLE65_000241"
     CDS             80821..81051
                     /locus_tag="SLE65_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8447567.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            81549..81749
                     /locus_tag="SLE65_000242"
     CDS             81549..81749
                     /locus_tag="SLE65_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEI8447568.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            81776..82969
                     /locus_tag="SLE65_000243"
     CDS             81776..82969
                     /locus_tag="SLE65_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEI8447569.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(83037..84602)
                     /gene="guaA"
                     /locus_tag="SLE65_000244"
     CDS             complement(83037..84602)
                     /gene="guaA"
                     /locus_tag="SLE65_000244"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEI8447570.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(84661..85584)
                     /locus_tag="SLE65_000245"
     CDS             complement(84661..85584)
                     /locus_tag="SLE65_000245"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEI8447571.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            85780..86385
                     /locus_tag="SLE65_000246"
     CDS             85780..86385
                     /locus_tag="SLE65_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEI8447572.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            86693..87709
                     /locus_tag="SLE65_000247"
     CDS             86693..87709
                     /locus_tag="SLE65_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEI8447573.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            87850..89151
                     /locus_tag="SLE65_000248"
     CDS             87850..89151
                     /locus_tag="SLE65_000248"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEI8447574.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            89197..89859
                     /gene="deoC"
                     /locus_tag="SLE65_000249"
     CDS             89197..89859
                     /gene="deoC"
                     /locus_tag="SLE65_000249"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEI8447575.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            89880..90278
                     /locus_tag="SLE65_000250"
     CDS             89880..90278
                     /locus_tag="SLE65_000250"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEI8447576.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            90344..91426
                     /locus_tag="SLE65_000251"
     CDS             90344..91426
                     /locus_tag="SLE65_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HEI8447577.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            91638..93200
                     /locus_tag="SLE65_000252"
     CDS             91638..93200
                     /locus_tag="SLE65_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8447578.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            93193..94326
                     /locus_tag="SLE65_000253"
     CDS             93193..94326
                     /locus_tag="SLE65_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8447579.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            94326..95282
                     /locus_tag="SLE65_000254"
     CDS             94326..95282
                     /locus_tag="SLE65_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8447580.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            95381..96547
                     /gene="deoB"
                     /locus_tag="SLE65_000255"
     CDS             95381..96547
                     /gene="deoB"
                     /locus_tag="SLE65_000255"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEI8447581.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            96571..97389
                     /locus_tag="SLE65_000256"
     CDS             96571..97389
                     /locus_tag="SLE65_000256"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEI8447582.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            97406..98113
                     /gene="deoD"
                     /locus_tag="SLE65_000257"
     CDS             97406..98113
                     /gene="deoD"
                     /locus_tag="SLE65_000257"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEI8447583.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(98411..99097)
                     /gene="gpmA"
                     /locus_tag="SLE65_000258"
     CDS             complement(98411..99097)
                     /gene="gpmA"
                     /locus_tag="SLE65_000258"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HEI8447584.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(99269..99850)
                     /locus_tag="SLE65_000259"
     CDS             complement(99269..99850)
                     /locus_tag="SLE65_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8447585.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(99983..100666)
                     /gene="rpiA"
                     /locus_tag="SLE65_000260"
     CDS             complement(99983..100666)
                     /gene="rpiA"
                     /locus_tag="SLE65_000260"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEI8447586.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            100985..101398
                     /gene="rpsL"
                     /locus_tag="SLE65_000261"
     CDS             100985..101398
                     /gene="rpsL"
                     /locus_tag="SLE65_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEI8447587.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            101482..101952
                     /gene="rpsG"
                     /locus_tag="SLE65_000262"
     CDS             101482..101952
                     /gene="rpsG"
                     /locus_tag="SLE65_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEI8447588.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            102046..104133
                     /gene="fusA"
                     /locus_tag="SLE65_000263"
     CDS             102046..104133
                     /gene="fusA"
                     /locus_tag="SLE65_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEI8447589.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            104305..105492
                     /gene="tuf"
                     /locus_tag="SLE65_000264"
     CDS             104305..105492
                     /gene="tuf"
                     /locus_tag="SLE65_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEI8447590.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            105899..106207
                     /gene="rpsJ"
                     /locus_tag="SLE65_000265"
     CDS             105899..106207
                     /gene="rpsJ"
                     /locus_tag="SLE65_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEI8447591.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            106238..106867
                     /gene="rplC"
                     /locus_tag="SLE65_000266"
     CDS             106238..106867
                     /gene="rplC"
                     /locus_tag="SLE65_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEI8447592.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            106895..107518
                     /gene="rplD"
                     /locus_tag="SLE65_000267"
     CDS             106895..107518
                     /gene="rplD"
                     /locus_tag="SLE65_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEI8447593.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            107518..107808
                     /gene="rplW"
                     /locus_tag="SLE65_000268"
     CDS             107518..107808
                     /gene="rplW"
                     /locus_tag="SLE65_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEI8447594.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            107847..108680
                     /gene="rplB"
                     /locus_tag="SLE65_000269"
     CDS             107847..108680
                     /gene="rplB"
                     /locus_tag="SLE65_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEI8447595.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            108723..109001
                     /gene="rpsS"
                     /locus_tag="SLE65_000270"
     CDS             108723..109001
                     /gene="rpsS"
                     /locus_tag="SLE65_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEI8447596.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            109024..109371
                     /gene="rplV"
                     /locus_tag="SLE65_000271"
     CDS             109024..109371
                     /gene="rplV"
                     /locus_tag="SLE65_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEI8447597.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            109385..110041
                     /gene="rpsC"
                     /locus_tag="SLE65_000272"
     CDS             109385..110041
                     /gene="rpsC"
                     /locus_tag="SLE65_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEI8447598.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            110044..110478
                     /gene="rplP"
                     /locus_tag="SLE65_000273"
     CDS             110044..110478
                     /gene="rplP"
                     /locus_tag="SLE65_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEI8447599.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            110468..110656
                     /gene="rpmC"
                     /locus_tag="SLE65_000274"
     CDS             110468..110656
                     /gene="rpmC"
                     /locus_tag="SLE65_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEI8447600.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            110681..110947
                     /gene="rpsQ"
                     /locus_tag="SLE65_000275"
     CDS             110681..110947
                     /gene="rpsQ"
                     /locus_tag="SLE65_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEI8447601.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            111005..111373
                     /gene="rplN"
                     /locus_tag="SLE65_000276"
     CDS             111005..111373
                     /gene="rplN"
                     /locus_tag="SLE65_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEI8447602.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            111410..111718
                     /gene="rplX"
                     /locus_tag="SLE65_000277"
     CDS             111410..111718
                     /gene="rplX"
                     /locus_tag="SLE65_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEI8447603.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            111746..112285
                     /gene="rplE"
                     /locus_tag="SLE65_000278"
     CDS             111746..112285
                     /gene="rplE"
                     /locus_tag="SLE65_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEI8447604.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            112304..112489
                     /locus_tag="SLE65_000279"
     CDS             112304..112489
                     /locus_tag="SLE65_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEI8447605.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            112525..112923
                     /gene="rpsH"
                     /locus_tag="SLE65_000280"
     CDS             112525..112923
                     /gene="rpsH"
                     /locus_tag="SLE65_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEI8447606.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            112955..113491
                     /gene="rplF"
                     /locus_tag="SLE65_000281"
     CDS             112955..113491
                     /gene="rplF"
                     /locus_tag="SLE65_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEI8447607.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            113652..114008
                     /gene="rplR"
                     /locus_tag="SLE65_000282"
     CDS             113652..114008
                     /gene="rplR"
                     /locus_tag="SLE65_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEI8447608.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            114029..114529
                     /gene="rpsE"
                     /locus_tag="SLE65_000283"
     CDS             114029..114529
                     /gene="rpsE"
                     /locus_tag="SLE65_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEI8447609.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            114544..114723
                     /gene="rpmD"
                     /locus_tag="SLE65_000284"
     CDS             114544..114723
                     /gene="rpmD"
                     /locus_tag="SLE65_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEI8447610.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            114767..115207
                     /gene="rplO"
                     /locus_tag="SLE65_000285"
     CDS             114767..115207
                     /gene="rplO"
                     /locus_tag="SLE65_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEI8447611.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            115207..116502
                     /gene="secY"
                     /locus_tag="SLE65_000286"
     CDS             115207..116502
                     /gene="secY"
                     /locus_tag="SLE65_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEI8447612.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            116564..117211
                     /locus_tag="SLE65_000287"
     CDS             116564..117211
                     /locus_tag="SLE65_000287"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEI8447613.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            117402..117620
                     /gene="infA"
                     /locus_tag="SLE65_000288"
     CDS             117402..117620
                     /gene="infA"
                     /locus_tag="SLE65_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEI8447614.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            117653..117769
                     /gene="rpmJ"
                     /locus_tag="SLE65_000289"
     CDS             117653..117769
                     /gene="rpmJ"
                     /locus_tag="SLE65_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEI8447615.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            117787..118152
                     /gene="rpsM"
                     /locus_tag="SLE65_000290"
     CDS             117787..118152
                     /gene="rpsM"
                     /locus_tag="SLE65_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEI8447616.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            118180..118569
                     /gene="rpsK"
                     /locus_tag="SLE65_000291"
     CDS             118180..118569
                     /gene="rpsK"
                     /locus_tag="SLE65_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEI8447617.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            118649..119587
                     /locus_tag="SLE65_000292"
     CDS             118649..119587
                     /locus_tag="SLE65_000292"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEI8447618.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            119615..119995
                     /gene="rplQ"
                     /locus_tag="SLE65_000293"
     CDS             119615..119995
                     /gene="rplQ"
                     /locus_tag="SLE65_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEI8447619.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            120267..121106
                     /locus_tag="SLE65_000294"
     CDS             120267..121106
                     /locus_tag="SLE65_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HEI8447620.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            121082..121951
                     /locus_tag="SLE65_000295"
     CDS             121082..121951
                     /locus_tag="SLE65_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HEI8447621.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            121941..122738
                     /locus_tag="SLE65_000296"
     CDS             121941..122738
                     /locus_tag="SLE65_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEI8447622.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            122941..123687
                     /gene="truA"
                     /locus_tag="SLE65_000297"
     CDS             122941..123687
                     /gene="truA"
                     /locus_tag="SLE65_000297"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEI8447623.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(124020..126689)
                     /locus_tag="SLE65_000298"
     CDS             complement(124020..126689)
                     /locus_tag="SLE65_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEI8447624.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(126927..127115)
                     /locus_tag="SLE65_000299"
     CDS             complement(126927..127115)
                     /locus_tag="SLE65_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEI8447625.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            127385..127747
                     /locus_tag="SLE65_000300"
     CDS             127385..127747
                     /locus_tag="SLE65_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEI8447626.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            127799..129481
                     /locus_tag="SLE65_000301"
     CDS             127799..129481
                     /locus_tag="SLE65_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEI8447627.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            129598..131634
                     /gene="recG"
                     /locus_tag="SLE65_000302"
     CDS             129598..131634
                     /gene="recG"
                     /locus_tag="SLE65_000302"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEI8447628.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            131683..132684
                     /gene="plsX"
                     /locus_tag="SLE65_000303"
     CDS             131683..132684
                     /gene="plsX"
                     /locus_tag="SLE65_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEI8447629.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            132806..133048
                     /gene="acpP"
                     /locus_tag="SLE65_000304"
     CDS             132806..133048
                     /gene="acpP"
                     /locus_tag="SLE65_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEI8447630.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
BASE COUNT        42632 a        23949 c        27250 g        39257 t
ORIGIN      
        1 ttcatcagga gtgtttcccg attcgttttt ggctgccgta gcaactttta tatcatatca
       61 gagagacaag taattgtcaa ctctttttta aaagtttttt cgatttcgtt tttcgaaatc
      121 ttccagcaac tcatttatca taacttatcg tttgttattt gtcaagaact tttttgaagt
      181 ttttttcgat agaatcaagc ttcgcaagtg gttctttttt aacgactcag ttatcttatc
      241 atgtcatttc caacatgtca acaacttatt ttttattatt taataagtta ttggtgttct
      301 tttgaacaaa taataatata tcaacatcac atgtgaaagt caataagaaa atgcttattt
      361 atcaacattt ctagcttaca tgatcattgg ttagttctgg tcctttttcg ttcgtcttta
      421 taactccgag agacgtaaaa tccttttgtt ttcagtttaa tgttcatgtt cttgtcttat
      481 tcacaccaac tagatgtctc accttctaaa attttcctta acaaagtgct gcttttatct
      541 atttctgctt ttttttgcta gaataatagt aacaatatga ctctggagga tttatttatg
      601 aaaattttga ttgctgacga tgataaagaa atcgttgaat tattaagtat ctatgttcac
      661 aatgaggggt atgaagcagt aaaggcttat gatgggaaag aagcattatc taaaatcaga
      721 acaatccctg atattgaatt acttatttta gatatcatga tgcctgagat ggatgggatg
      781 caagtagtga aagagctacg aaaagaatcc caaataccaa tcattatgct gacagcaaaa
      841 actactgata tggataagat caaaggactg gtcgctggtg cagatgatta tgtgaccaag
      901 ccatttaatc cgttagaagt aatggctaga gtaaagtctt tattacggcg tacaaaaatg
      961 cagattgccc cagatcagcc tgatgtatta gaagtaaatg cattaatcat caataaagac
     1021 tctcatgaag ttaaaacaat cgatgggaaa gaaatccagt taacagcttt ggaattcggt
     1081 atcctctact tgcttgctag tcatcctaat cgagtattta gcgcggatga aatttttgag
     1141 cgtgtttgga aacaagaaag tattgtctct gctaaaactg tcatggttca cgttagtcat
     1201 ttaagagata agattgaaga agcaactggt ggtgaaaaag tcattcaaac cgtttgggga
     1261 gtgggctata aaattgacgc aagatagtaa acgagcaact gaaaaacgcc gtcggatcaa
     1321 tttgacttca aaagaaatca gcgaattgtt agcggaagga atcatcacga ttatcctttt
     1381 gcttctatta aatgtttcta ttctggttgt tatcagttcg gtgatcaaca gttcaccttc
     1441 tttgacgaat gcgatttggg attcaaagaa tatttttgca gaacgattga acactgattt
     1501 gttctggaac ggccggaatt ttattattcc ctttttcttt ctattagata ttggtgtttt
     1561 gtattggcgc ttgattcgaa gatatcgcca aatgcaattg cggcatatca tcagcgaact
     1621 tcactacatc gcaaacggaa attatgatca tcgtatccct tttgaactga gtggtgactt
     1681 aagccgagtg gtaacaagta tcaatggatt ggtggatagt accgtagcag cgattgaaga
     1741 cgaacgtaaa atcgaaaaat caaaagatga attgatcacg aatgtcagtc atgatatccg
     1801 taccccactc acgtccatca ttggatacct aggactgata gaagatggcc agtatcactc
     1861 agaagaagat cttttaaagt atacgcatac tgcttatatc aaagcaaagc agatgaaatc
     1921 tttagtggac gacttatttg aatacactaa ggtacgccag cctgctgtcc cggtgaattt
     1981 ttctgccttt gacatgatcc agttgatcga acagttagca gctgattttg agttggaagc
     2041 ttctaaaaaa aatatccaaa tacttgttca atcaaaagta gactccctta tcatggatgg
     2101 cgataccgaa aaacttgtac gtgtcttcaa taatcttttg acgaatgcgt tgaaatacgg
     2161 aaaaggagca acgaagatcg taatcgaagt agaacgtatc ggttcagaag ttgttgcaac
     2221 agtcaaaaat aacggagcaa tgatcccaca acaggcaatc gataatctat tcgaccgttt
     2281 ttatcgtgta gaagaatctc gttcacaagc aactggagga actggacttg gtttagcaat
     2341 cgctcaaagc attgtggctt tgcacggcgg atacatttat gcaaaatcag ataagcaatg
     2401 gacttctttc atcatgcacc ttccaatcaa gaaaaatgaa aaattaccta ttgatacaca
     2461 ggaagttatt gacgaaagct gaaatattcg ctattcttat tacaattatt agaataaatg
     2521 aaaaacacag aacccagtac actttattct ttttcagaga gctgatggca ggtgtaaatc
     2581 agcaaaggat aatttggaag ttccagttcg tttacgtgcc ctttcgaaat aagaaaggtc
     2641 ggttcaacag ccgttatgtg ttcaacaagt gcagctgacg ctgaacttgg gtggtaccgc
     2701 gaatttcaga ctgattcgtc ccaagaataa tgggatggat cagtcttttt ttattttcaa
     2761 aaaggaggaa atcatatgtt agatgtaaaa atgatgcgac aaaatattga agaagtacaa
     2821 gaaaaattga tgactcgggg cgtaaaaaaa gaaacattag ctgaattcat ggaactagat
     2881 gaaaatcgtc gtaagctact agtcaaaagt gaagaattaa aaaaatatcg aaatgatgtt
     2941 tctgctgaga tcgcccaatt gaagcgtgca aaagaagatg cttctgctaa aatcgctgaa
     3001 atgaaagaag tcggtggcaa catcaaagca ttggatactg aaattgctga agtggatgaa
     3061 aaattgaaac aaattgcaac tactttgcca aaccttcccc atgattctgt gccagttgga
     3121 acagatgaag aggacaatgt agaaatccgt cgttggagcg aaccacgtac atttgctttt
     3181 gaaccaaaac cacactggga aattgcagaa aatcttgata ttttagattt tgaacgtggc
     3241 gcaaaagtag ccggtagccg ttttgtctat tacaaaggat taggtgctcg attagaacgt
     3301 gctgtctaca acttcatgct tgatcagcat atttacgaac acggctatac tgaaatgatc
     3361 actccttata tcgtcaacag taaagcgatg tttggtacgg gacaatttcc aaaattcaaa
     3421 gaagatgttt tccaattgga gaatactgat ctaacattaa tcccaacagc tgaagtacca
     3481 ttaactaact attataatga tgaaatttta gatggtgcag atttacctat ttatttcact
     3541 gcactaagcc ctgcttttcg ttctgaagcc ggaagtgctg gtcgggatac acgaggactg
     3601 attcgtcttc accaattcaa taaagtagaa atggtcaaat tttcggatgt agagcattct
     3661 tacgaagaat tggaaaaaat gacagctgat gcagaagata tcttgaaaaa attgcatttg
     3721 ccttatcgtg tgatggcctt atcaactgga gacatgggct tttctgcagc taaaacttat
     3781 gacttagaag tatggatacc tgcacaagat acttatcgtg aaatcagttc ttgttctaac
     3841 tgtgaagatt tccaagcacg ccgcgcaatg atccgttatc gcgataatga tggaaaaatc
     3901 cactatactc atactctgaa tggttcagga cttgcagttg gccgtacagt agctgccatt
     3961 ttggaaaact accaaaatga agatggttct gtcacagttc cagaagcgct cgttccttat
     4021 atggggaatc tgaaagttat taaataaaga ggctgtgaaa aagccgctta gtttcgagta
     4081 ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaattgga cttaataccg
     4141 agaaactggc ttttgaacac catttatcga gaggttgtga aatcagcgaa ttaacctgag
     4201 tattagagaa aaaaatggaa aaatagtccc tcatatttta ccgtttgttg aactaatacc
     4261 gagggtcagc tgattgaaca ccgtttagtg gagaggtcgt aagcctaccc cccagctcct
     4321 agttacaagg acaaattcaa aaaacagctc ttcatatttt atgaatgttg tacttgtgat
     4381 tcggaggtgg caagggaaca ctgtttattc aaaaagaggc tgggacagaa gcgtttaact
     4441 ccaagaaata agaagaaatt cacgaaaatt gcttttcaaa tttttgtgaa tttcttctta
     4501 tttccgaagg agttgcttct acttccgccg tttatacgtg tttagagcgt gagacaaaag
     4561 tgttctttac ttttgtccca cgctctttaa tgtttttaag attcaactga atagtttggt
     4621 gcttcttttg tgatttgtac atcatgaggg tgtgattctt ttaatccact gccgctcatt
     4681 tggataaatt gcgcttcatc acgtaattgc tgtagattgg ctgccccaac ataacccatt
     4741 cctgaacgca aaccgccgat catttggaaa ataatatctg caacacttcc tttataagca
     4801 acccgacctt cgattccttc tggtactaat ttatttgctt cattgacact accttggaag
     4861 taacggtctt ttgaaccttt ttccatcgcg cctaatgagc ccatacctcg gtatgttttg
     4921 aatcgacgtc cttggaagat ttcgaattca cctggtgatt catctgtccc tgccaacata
     4981 cttcctagca tcactgcatg tccgccggca gctaatgctt tgacgatgtc accagaatat
     5041 ttgatccctc cgtctgcaat aatcgctttg ccatattgac gagcaactga tgctgcatca
     5101 taaatagctg tgagctgagg tacacctaca ccggctacca cacgtgtcgt acaaatcgat
     5161 cctggtccga taccaacttt tacgacatct acacctgcat catataaagc ttttgtcgct
     5221 tcagccgtcg caacgtttcc tgcaatcaat gttgcatctg caaaagttga acggatttct
     5281 tgaatttttc ggatcacacc tgcactatgt ccatgagctg tatcgatgat gattgcatct
     5341 gcccctgctt ctaataaagc attcgcacgc tcaaatgtat cgcttgttac accaacggct
     5401 gctgctacaa gcaatcgacc atgttcatct tttgctgcat ttggaaattc gatcactttc
     5461 tcgatgtctt tgatcgtgat caatccgctt aaacgacctt cgttatctac gattggtaat
     5521 ttttcgattt tatgtttttg caaaatcttt tctgcatctt ttagagaggt acctactggg
     5581 gcagtcacta agttgtcttt tgtcatcaca tcagcaatcg gcatgtgata atctgttaca
     5641 aaacgcatgt cgcggtttgt aattatccct accaattttc tgttttcaag tgtttcaacg
     5701 attggcacac cactgatacg atatttgctc atcaattctt ctgcgtctgc tacaagatgc
     5761 tgtggcgtta agaagaacgg atcaatgatt acgccacttt cagaacgttt gacttttctt
     5821 acttcatccg cttgctggct gatcgtcatg tttttatgga tcacacctag tccgccttgt
     5881 cttgccatag caatggccat cttgctgtcg gtaacagtat ccatacttgc actgatgatt
     5941 ggaatattca acttaatatt tttagctaat tgtacgctca tatccacttc gtttggtaac
     6001 acgtgacttt ctgctggtat caataagaca tcatcaaaag taaatccttt tttcgtgaac
     6061 tttgtttccc agttggacat ttttagtacc actcctctaa tttagtttat ctattaaaat
     6121 aattgatttt ttcatttaag tcaatgatct acttggaatc aagttagctt tctcatagaa
     6181 taccaatata aagcgtttac atctgtgtat attaaaagag attgtaaaaa agctgtcctg
     6241 catcaagtaa taagaacagc caatcaaaaa cagcttctca tgtttttgaa ttggttgggt
     6301 ttattaccgc agatgcaaac ttttgaacac cgtttagtgg agaggctgtg aaaaagctgc
     6361 ttagtttcga gtagtaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt
     6421 ggacttaata ccgagaaact ggcttttgaa caccgtttat cgtaaaaagg gactgtgaca
     6481 agacttttgt cacagtccct tactattatt taactatgga taaacaaaat gaggttcttt
     6541 actaccccta gatatctagc aaaatagctg atctttttgc tagtttatct tcttgggacg
     6601 gataaacttc caataatccc gtattttttc ttcaagtagt aacggattgc taaagcagtt
     6661 gccccgataa tgataactac tactggatct aatactggat tgataactgg tggcaatagt
     6721 gttgtcgcag aaaacagtac gacccaaaga agtgtcgttc cacctaggat aagcaatgtc
     6781 ttacccattc ctggtttctt gcttcgatct gctccgggat attcatattg atagatgtat
     6841 ttgtacatca tataaaagac ccagccaccg attgcagaac ctagaacgag tgtagaaaag
     6901 ccataagctg gcgttgttcc acgtgaaaac aatccggtaa tcgcaatcat gatacttaat
     6961 agaccaagca acagcaacgt attatctaac cacatcaata aaggggtgga tgaatttttt
     7021 acttctgctg gcttattgat gattgcttcc gttctttcag agactgtccc aaacaattga
     7081 cgggctgttc ttccgccttt ttgttctgca actaaagtag gcagaatgtc atgaagggct
     7141 tttacttttt cttcttcaga caaattcgct gcttctaaag attttttcaa atcaaaaatg
     7201 tactgttgat ttcttttggt taattttgtt tctaaactat tgttttcttt tacgattgct
     7261 cgtaattgtt ctggttccat tatctaatag tcctccttag ccgttccttt tctcaacggt
     7321 cgtcacaaaa gacattctac catattctac agctagtttg atagcccttt tacacattaa
     7381 agcggaataa cattacgtcg ccgtcttgta cgacataatc ttttccttct aatcgaacac
     7441 gtccagcttc ttttgctgca tgcatgtttc cgtaatgatc caagtcttca aaagagacag
     7501 tttctgcacg gataaatccg cgttcgaaat ctgaatggat gattcctgct gcttgtggtg
     7561 ctttgattcc ttttttgaat gtccaagcac gtacttcttg ttccccagca gtaaagtaag
     7621 tagctaagcc taacaaatca taagcagcac ggatcaactg atccaaacct gattcttcga
     7681 ttcctaaagc ttctaaaaat tccgctttgt cttcttcatc taattctgcg atttcttctt
     7741 ctgcacgagc actgaccacg atcacttctg cattttcttc tgcagcaaag ttgcgcactt
     7801 cttgtacata atgattcgcg tctgcatctg ctacgtcatc ttctgagaca ttggctacat
     7861 aaagaattgg ttttgtcgtc aataaaaata gtgatttaac gattttttgt tcttcttcag
     7921 taaattcgat cgttcgggca gattttcctt cttccagtac aggtttgatt ttatccagta
     7981 cagctagttc tgccactgca tctttatctt tggttttagc aacttttgct acacgagtat
     8041 agcgtttgtt gatagattct aagtctgcta acactagttc caagttgatc gtatcaatat
     8101 cttctagtgg atcaacacgt ccttctacgt gagtaatatt atcatcatca aaacagcgaa
     8161 caacgtgaca aatagcgtct acttggcgga tatggcttaa gaattgattt cccaaacctt
     8221 ctcctttact tgcgcctttt acgattccag caatatctgt aaattcaaaa gtcgtcggaa
     8281 cagttttttt cggatgtaca agttctgtta agcgttgcaa acgccagtca ggtacttcta
     8341 ccatccctac gttggggtcg atcgtcgcaa agggatagtt tgctgcttct gctcctgctt
     8401 ttgtgatcgc attaaacaaa gttgattttc ctacgttggg caacccaaca attccagcag
     8461 tcaatgccat aaatttattc actctttctc tgcatttttt tcaattactt tttttaattt
     8521 cttttcaaaa tctcgacggg tcatcatgac gatatgtccg caattcatac atctgatttt
     8581 gatatctgcg cccattcgaa tgacttccca gcgattcgtc tggcaagcgt gaggtttttt
     8641 catttcaacg atatcgtgca agtcgtacat aaaaatagcc tcctttttgt ttattcttca
     8701 tcaaattgaa tattcaagat atcaagaatt cgagtcaaat ctttttgaga aagatattca
     8761 atctcgatct tacctttccc atttttttct tggatagcta cacttgtacc aaatttatcc
     8821 atcaaacgat cttcgctttc tcggatataa tatggttttt cctttgctag ccttgggatt
     8881 tttttctttt cttttccatc attttgattt aactcagaaa caagctgttc cagttggcgg
     8941 acagttaaat tttcagttac tgcacgattg gctaatttca agatcaatgt tttatttttt
     9001 aaacctaaca gcgtacgggc ttgtcccata gataaacgct gatcttgtac catttccttg
     9061 acaagatccg gtaaagaaag caagcgcaaa taattggcga tataaggtct gctctttcct
     9121 aaacgactag ctacttctgc ttgtgttagt ttcaggtttt tcatcagcat ctcatatgct
     9181 tctgcttctt ctaacggatt cagatcttct cgctgcaagt tttccagcac tgctacttgc
     9241 atcatcgctt cttcgtcaaa gtctctaacg atagcaggga tcgtttcttt ttcagctagt
     9301 ttggacgctc gaaaacgtcg ctcccctgca ataatctcat atccttttac tgcggaacgg
     9361 cgtacgatga tgggttgaaa gacacctgat tgttcaatag aattagctag ttcctgcaaa
     9421 gatacttctt caaatgtttt acggggctga tacggatttg gtcgcagctc attcaatggt
     9481 agctggacaa cggtatcatc ttttacatcc accgtctcta agttttctaa atcttgaaac
     9541 agtgcatcga ttcctcggcc taatccttta cttttcttca cgacttacca cttcctttgc
     9601 caatgcttgg tagacttcag ctcctcgaga acgtggatcg tagtcgatga tcggttttcc
     9661 atgactaggt gcttctgata aacgaatatt tcttggaatg atcgtttcgt aaactttttc
     9721 gcggaagtat ttacgtactt cttctacgac ttcatttccc agatttgttc gtgcatcata
     9781 cattgtcagt aagactccct cgatctctaa ttctggatta aagtgttttt ggactaaacg
     9841 aaccgtattc agtaattggc ttaatccttc caatgcgtaa tactcacact gaacaggtat
     9901 caaaatcgaa tcacttgctg taaatgaatt gattgtcaga tggccaagag aaggcgggca
     9961 atcgatcaaa atataatcat actgactgct tacttctgct aaagatcctt ttaatcttga
    10021 ttctcttgcc atcattgacg tcaattcgat ctctgctcct gctaattgga gagtcgcagg
    10081 cacaatactc aaattttcgt gttcagtgat caaagttgcc tcatcaattg gcaattcatt
    10141 gactagaaca tcatagatgt ctcttgtcac atcaggtttt ctgatcccga caccactggt
    10201 agcatttcct tgtgcatcca tatccactag caatactttt ttgccaaggc tagcaagaca
    10261 agcacctaga ttcaccgtcg tcgttgtttt gccgacgcca cctttttggt tcgcaacaga
    10321 tattatttgt gccatctctt ctcctcctat ttgattggct gcttattagg cagtccgggc
    10381 tttcttgggt atttctttgg ggttggtttc tttttttgaa taacgatgat atgccgttga
    10441 tcagagacat tcggcaaggt aaccgcctct tctttgagga atttaccacc taataaagca
    10501 atcgcttgtt ttgcttctgt caattcctct tcactttttg ctgctttcaa tgcataaaaa
    10561 tagccttctt gtttagccaa gggcaaacac aattccgcta acacattcaa acgagcaacc
    10621 gcacgagcag tgacaaggtc aaatgatgca cgaaagtgag gattttgccc aaatgtttct
    10681 gcccggtcat gatataagga agcatcgatt cctaataatc gggttaactc agataagaag
    10741 gttattcgtt tattcagaga atcaacgatc gttatctgca gttctggaaa ggcaattttt
    10801 aaaggtatgc taggaaaccc tgcccccgaa ccaacatcgc ataaagataa aggttgcgta
    10861 aagtctactt caaatgctaa tgtaagtgaa tcgtaaaaat gcttcagata tacgtctttt
    10921 tcatccgtaa tagctgtaag gttcatcttt tcgttccatt cgactaatgt ccgataataa
    10981 atagcgaatt gattcatttg atgatcggta agctctatcc ctttttctgc caaggattgg
    11041 cgaaattctt ctggtatcat aaatattcct ttcattgtga aacagcaatt gtttcacaga
    11101 ttctctccct actttaacgc aaaatctcta gacatgcaat ccttccatat ggattcttaa
    11161 aaatttgaaa agtaagaaaa gccgatagac tttttctttc tagtatgact cataaaatat
    11221 acacagaaga gagaactagc tttgagcaat ttctgcaaaa actagttctc tcttctattt
    11281 attattacgt attacgctgg ttcactgact ttcgcaatct tcccttgttc gatatagacc
    11341 attaggatac ttaggtctgc agggtttacg ccactgattc ggctagcttg ggcaattgtt
    11401 tctggttgga ttttctgcaa tttttgtttt gcttctgttg ctaatccgtt gattgctgcg
    11461 tagtcgatgt tttctggaat ctttttcgct tccatgcgtt ttaatttttc tactttttcc
    11521 atggcttttt tgatgtagcc ttcatatttg atttggattt ctacttgttc gatttctttt
    11581 cgtgtcaatt cttcattttc tggaataaac cgtagaagtt ctgcataagt aatctcagga
    11641 cgtcttaaaa agtcgcttgc tagtacacca tcttttaatg gtgccgcatt aatcgttgct
    11701 aaaaagtctt ggacttcttc tgttggtttg attcgtacat tcatcaaacg tttgatttct
    11761 tgttcaactg cttctttttt cttcaaataa ttcttgtatt gatcttcttt tactaagcct
    11821 acacggtgac ccatttctgt taatcgcaaa tctgcattat catgacgtaa aagcagacgg
    11881 tattcagcac gtgaagtcag caaacgataa ggttcgttcg ttccttttgt taccaaatca
    11941 tcgatcatga caccgatgta accgtcactt cgtttgatca ctaaaggttc ttttccctga
    12001 actttcaaag ctgcattgat accggcaatc agcccttgtc cagccgcttc ttcataaccg
    12061 cttgtaccat ttgtttgtcc agctgtataa agattttcaa cgactttagt ttctaatgtc
    12121 ggacggagct ggtgtggctc tactacgtca tattcgatag catatcctgt acgcatcatt
    12181 tctacttttt ctaatccagc aatagaatga agcatgttga cttgaacatc ctctggtaaa
    12241 gaagtagata aaccttgaac atagacttct tccgtattta agccttctgg ttccaaaaat
    12301 aattgatgac gtggtttgtc tgcaaaacgc acgatcttat cttcgatgga tggacaatag
    12361 cgagcgccta ccccttcaac gatccctgta aacattgggg cacgatgtaa gttgtctcga
    12421 ataatttggt gagtcgtctc acctgtatag gtcagccagc aagattcctg atctagttta
    12481 taggcactat ctggtgtgct gaagctaaaa tgattcggct ctttgtcacc aggctgctct
    12541 tctgtaacag aatagtcgat cgtacttgat tttactcgag gcggtgttcc tgttttgaac
    12601 cgttcgatag caaagccaag ttcttttaga tgattcgcta gtccaataga aggttgagag
    12661 ttattcggac ctgatgaata tttcaattca ccgataatga tttctccgcg aagtgctgtt
    12721 ccggctgtaa taacaactgc tttggcccgg tagctcgctc ctgtggacgt cactactcca
    12781 tgacaaacac catcttcgac gatcagttct tcgacgattc cttgtcttag cgtcaaattt
    12841 ggttcttttt cgatcgtatg tttcatttct gttgaataag catgtttgtc tgcttgtgct
    12901 cgcaatgctc ggacagctgg gccttttcct gtgttcaaca tacgcatttg gatataggtt
    12961 ttatcgatat tcttacccat ttctccgcct aacgcatcga tttctcgaac gacaacgcct
    13021 ttagctggtc cgcctacaga aggattacat ggcatgaatg ctaccatgtc caaatttatt
    13081 gtcagtaata atgtttttga tcccatacgt gcagcagcaa gtgcagcttc tgaaccggcg
    13141 tgtcctgcgc caacaacgat cacgtcatac gcatctgctt cataatgttc caatcgtttg
    13201 ttcctccttt tattttccta aacaaaattg actgaataat tgagtgatta gctcatcttg
    13261 tacactgtcg ccgacaactt ctcctagata gtcccagcaa cgcgtcatat ctatttgaac
    13321 gagatccaca ggcattcctg aatcaatacc tgcaatgact tcttcaagtg agagggaagc
    13381 tttttctaac aacgcgatat ggcgggtatt agaaacataa gtagcgtctc tttctcctgt
    13441 ttctccgctg aagaataaat cagaaatagc tgattccaaa cgatctagtc cgtcgttttt
    13501 agctacggaa attgaaaaaa ctggttcatt ttcgatcaat ttcttcaatt tttcttgttc
    13561 cagctgtgct ggcaaatctg ttttatttag aagaatgatc cgtttcaatc cacttgtcgc
    13621 ttccaataat tgttcatctt ctgctgtcag tggttcgctt tggtttagaa caagtaagat
    13681 caagtctgct tctgctaatg cttttcggct tctttcgacc ccgatccgtt ccaccacatc
    13741 ttctgtttcc cgaattccag ctgtatcgat tagcttgagc ggtacccccc gaacattgac
    13801 atactcttcg attacatctc gagtcgttcc tgcaatatcc gtaacgattg ctttttcttc
    13861 tcttaacaaa tggtttaaca aacttgattt gccgacattt ggccggccga tgattgccgt
    13921 acttaaccct tcccgcagaa ccttcccttg cttggatgta gcaagtagcg cttggattct
    13981 ttgttggatc atctgcgctt tttcaagcaa taacttcgta gtcaattctt cgacatcatc
    14041 atattctgga taatcaatat ttacttctac ttgtgctaat gtctctaaaa tctcttgtct
    14101 caatgagcgg atcaaagcag acagattgcc gtctaactga ttaagagcta gtcccattgc
    14161 tttgtctgtt tttgcccgaa tcaaatccat cacagcttct gcctgtgaaa ggtcaacacg
    14221 accattcaag aatgctcgtt ttgtgaattc gcctggctca gctaatcttg caccttctct
    14281 taacaatagc tgcaaaattt gattgactac aacgatccca ccgtgacaat tgatttctac
    14341 tacatcttcc cgcgtaaatg tctttggtgc tctcatcacg gagaccatga cttcatcgac
    14401 aagctgattg ctcttgggat caacgatatg tccataatgg atcgtatgac ttggtacttc
    14461 tgataatcgt ttgtttccag attgataaac tttatctgct agttgcacag cttgatcgcc
    14521 acttaaacga acgatactga ttgcaccttc tccaggtggg gtagaaattg ccgcaatcgt
    14581 atcaaattct aaagtaattt cagccatttt ttcacttcct ttttcatttt gcgcacaaaa
    14641 aaagtgccca ctccaccctt tatgcacaat aaacggtgaa cttcgcactt tgactgcttg
    14701 ttcttgatta aattctggtc atagattatc acacttgcta taaggaatca agtgtttaaa
    14761 acaattagat gaagttgagc ctgttctgct tccattacct tatatttaat tgtccttgga
    14821 tgtctctttg cgttctttgg tttattcgaa gagaagatac tgtataaaca aggctttatc
    14881 tttcttaaaa aaaacggtac actaaatggt agcgctatct aaactataca cttttgaaag
    14941 gagaaaatat gtgagcccgt tcagatctgc tgcattggaa gaagaaagtg accctcggat
    15001 caacgatgtc gttttatcta cagggaatat caaccagaaa tatatcgtcc gcgatatcgt
    15061 ttttgttgtg gaatgcttag aagctgattt gtttgaccca tcttttccca aagatgacct
    15121 tttcttaaca acgaagagga aattaaagac gaaggtactt gaatatggtg cgaatgcagt
    15181 aatcaactgt cattttgagt atcagcaaaa aaaacgcgac ggaaagtatt ttctggaact
    15241 ttttgcttat ggaacagtga tccaatttat ccaaacaacg attggttaaa tgaaacagac
    15301 aaaaaaagcg gatcaaaact gaagacagtt tcgatccgct tttttctatc aaagttagtg
    15361 actacttcat cgtatactct gataagaatg atttctagta aaatatactt ggtttgaaaa
    15421 actttgtcaa cgtgatttat tcaaaaagta atggaatcaa taatattttt tagcaggttc
    15481 tactactaaa taacgataag gttcctcacc ttccgaatgt gtttttacat gttcatcttt
    15541 gcttaatgca gcatggattt gtttacgttc aaatgcaggc attggttcta agaaaacagg
    15601 ctgccctgtc cgttttactt tttcagccgt gcgatcagct aaacgctgaa tgatctcttg
    15661 gcgcttttca cggtaattgc ctacattgac tactacagac agcttatttc ttgctaaacg
    15721 atggatgaag acttgtgcca gatattgcaa tgcattcagt gtttttccat gtttcccaat
    15781 cagtatgcct tgcttttgtg tttctaaatg gaaaacaacc atattatttg attctctttc
    15841 cattttgaca agagctggag catcaagctg ttttgaaatt tcagtaagat aaactgccaa
    15901 ttccgttaaa gctgcttcat cacctagctc acttacttct tctgtttttt cttcaagaat
    15961 cgtttcgttg actacctcga tctcagctgt tggttcttct tccaaaattt cttctacagt
    16021 ctgttctact gtttcagaaa ctttttcgct gatacttggc tggatcgaaa gccgtgcatt
    16081 ctttcgaccc attcctagga aacctttttt tccttcttcc agtatttcga tttcgacttg
    16141 gtctttggcc aaacccaaat cagccagacc tagttggaca gcttcgtcta ttgttgcagc
    16201 ttcataaatc ggcattagca ttacctcccc tattatttcc gttttttctt aggattcatt
    16261 gctttcttaa gagcacgttc tctttcgcgg attctccgtg cttcttcttc acgctctttt
    16321 cgaattttga aagggttgtt gatcagcagc gtttgtacaa cttggaaggc attggaaact
    16381 acccagtata atgaaagacc gctggctaaa ttgacaccca tcactaaaat cattacaggc
    16441 atcacgaaat tcatgatctt cattgatgca ttcgattcaa tttgactcat gctagataaa
    16501 tacgtacttg caaaagtaaa gattgctgct aaaatcggca aaataaatgt tggatccgcg
    16561 ttccctaagt tcaaccataa gaaatgccct tgtttcaact ctggtacacg tgaaatagat
    16621 tgccataacg ccatcaagat tggcatttgt actaataaag gaagacaacc agcatatgga
    16681 ttgacgccat tttctgcata taaacgctgc tgctcttctc ttaacttact ttgtgtttcc
    16741 ggatctcttg aactatattg ttgctgcagt gcttttaatt tcggttgtaa ttcttgcgtt
    16801 ttacgcatgc tctttgtttg gaaatgcatc aacggcaata ggatcacgcg gatgatcagt
    16861 gtaaataaaa tgatccctat ccctgcatta ccaaatgaca acgccttgat cgcctcagca
    16921 aagtaataaa caatataacg atcccaaatt cctgtactct gtgcgctgac ttccccagtt
    16981 ccgcaaccgg ataagacgat gaccaaacta acgataccgg ccatcaaaag taaacgtttg
    17041 tatttcttca cttactcttt tcctctctgt cgattatttt tgcaagtttt aagacgtgga
    17101 ctaaattgga gcgaacctca tcataagtca accccttcac acttggtcta gcaatcacaa
    17161 taaaatccaa ctccggatca atttcttctt ttatagaata aactgctgct cggatttttc
    17221 gtttgacttc attgcggttt accgcgttgc cgaccttttt tcctacagat aaaccaactc
    17281 gaaaatgagg ctgtcccggt ttttccaaac ggtaaacgac gaatttgcgg ttagcaaaag
    17341 aatctcccgt atggaacacg gcttgaaact ctcgttcttt ttttactcga tacgcttttc
    17401 tcattagttt tctttccttt tctatctctc acttacgctc ataatcatac cataattacg
    17461 attgtccttt catcatttcc ctaaaaaaga gtataaaaaa aaccactgaa accccagtgg
    17521 cctaagctga aagaactttt cttcctttgc gacgacggct agctaacaca cgacgtccat
    17581 ttttagtact catacgttta cggaatccgt gaactttttg acgtttacgt ttatttggtt
    17641 ggtatgttct tttcatatat tccacctcca aaatgttctt atctatttta taaacacaga
    17701 catactttga tagtataacg acaaagtagt gattttgtca atataaaata gaagatcgat
    17761 tgttaaaact tatccacaag attatttttt tctatgggaa tcctatgtgg aaaaagttat
    17821 gcacagggat tatccacaga taataaaagg ctggttttac acagaaaaca cacgtgtaaa
    17881 aaaagtaatc cacaatcagg cgatttcctg tgtattccgt ctcctaacta ttggtatatc
    17941 tgtatttttt atccacagac gcaagaggaa atctattggt ttttacgagt tttccacctg
    18001 tgcattagtg gtgtggaaaa ctttttttga caactgtgtt tttctctttt ttctttttgt
    18061 cgattgtgtg gataattgta attaaaaaat ttttttcttc ggtttctgtg gaaaactatt
    18121 gaaaaaaatg ctaaattagt actagttatt cactttttaa tgaaggagga ggccttatat
    18181 ggtatccctc gatgctttat ggaatgaatt aaaagcaaca taccaaaagg atttatcgcc
    18241 tgctagctat aatacatgga tcgaaacagc gaaccctcga acccttgatc aaaaccagct
    18301 cgttgttgag gttcctagca agattcataa agaatattgg gaaaaaaacc tggcgacaaa
    18361 aatcgttgaa gtcggttata tgttatcagg aaatgagatt atccctcgct ttattactgg
    18421 cgaagaagca gagcaagaag aagttataga agaaaaaaat ccaaaagttg tggcacctag
    18481 tccgctaaaa aaagccatgc tgaaccctaa atataccttt gatacgtttg tcattggtaa
    18541 aggaaaccag atggctcatg cagcagcgct cgttgtagca gaagatccag gttctattta
    18601 taacccgctc ttcttttatg gaggcgtggg acttggtaag actcacttga tgcatgcaat
    18661 tggtcatcaa atgctgcaaa gtcagcctaa tgccaaagta aaatatgtaa gcagtgaaac
    18721 ttttgctaat gatttcatca attcgatcca aaacaaaaca gcagaagagt tccgtcaaga
    18781 atatcgaaat gttgatttac tgctagtgga tgacattcaa ttttttgcag aaaaagaagc
    18841 tacgcaagaa gagtttttcc atactttcaa tgccttgtac aatgaaggga aacaaatcgt
    18901 actaaccagt gatcggttgc caaacgagat tccgaaactg caagaacgcc ttgtttctcg
    18961 ctttgcatgg gggctgtctg ttgatattac accgccggat cttgaaacaa gaacagcgat
    19021 tttacgtaaa aaagcggcgg ctgaacgtct agagatccca gatgacacac taagctacat
    19081 cgcaggacaa attgattcta acattcgtga attagaaggt gcgcttgttc gagtgcaagc
    19141 ttttgctgcg atgaatagtg aagatatttc gactagtcta gctgcagacg cactgaaaac
    19201 gttaaaatca ggaaaaggac atcctcaatt gtcaatcctg cagatccaag aagaagtggc
    19261 aaagtattat cacatccaat tgaaagatct caaaggaaag aaacgcgtca aatctattgt
    19321 tgttcctaga caaatcgcta tgtatttggc acgtgagctc acagataatt ctttaccgaa
    19381 aatcggagct gaattcggtg gcaaggatca tacaacggtt atccatgctc atgaaaaaat
    19441 ccagcagctg atggattcta gtgtcagtat gcaaaatgaa gtatcagaaa tcaaaaactt
    19501 tttactaaat taatttgtcg attctatcaa ctgaaaatag catgtggata aaagaaaaaa
    19561 acgttcaaaa gttatacaca ctttttccac agctgttttt tcgtttctct cttacgtttt
    19621 ttgagttttc cacagaatca acatgcccta ttacttttat tattcttttt aactaataat
    19681 aaataaacaa acattcaaag gagatacatc atgaaagtta ctttaaaccg agctagcttt
    19741 atgcaggaat tgcaaactgt tcaacgagct atttcaagca aaaccacgat ccctattttg
    19801 acaggtgtaa aaatcacact gacacaagaa ggtttgactt tgacggggag caacgctgat
    19861 atatcaattg aaactttttt gtctgttgaa aacgaaaaag caaatatgca aatcgaatct
    19921 actggttcca ttgttttaca agcacgtttc tttagcgaaa tcattcggag acttcctgaa
    19981 gaaacattta ctttagaagt tttagaaaat aaacaagtag cgatcacttc tggaaaagcg
    20041 aattttatcg taaatggatt agatgcagat aactatcctc atcttcctgt tgtcgaaagc
    20101 cataaccaga tgaaattacc tgtacacgta ttgactaaac taatcaacga aacagttttt
    20161 gctgtctcac aacatgagag tcgtccaatc ttgacaggtg tgcatttcat tttatctgat
    20221 aattctttat tagctgtagc tactgattct caccgtctaa gtcaacgcgt gattccagta
    20281 gaacaagcgg ctgatcattt tgatattgtt attcctggaa aaagtttgat cgaattatct
    20341 cgctcattaa caaatgaaga agaaatcgtc gaaatcagca ttatggaaaa ccaagtgttg
    20401 ttcaaaacag aaacgatgta tttctattcc cgtttgctag aaggaaacta tccagatacc
    20461 aatcgtttga ttccttcaag ttttaataca gaggttgaat tttctgttcc tagcttttta
    20521 gcggcgatcg aacgggcttc tttactttct catgaaggcc gtaacaacat cgttcgttta
    20581 tctattcgtc cagatgcggt tgttttatac ggaaattcgc cagaaatcgg gaaagtagaa
    20641 gaaagcttga gttatacagc aagcagtggc gatccattag atatttcttt caatccggat
    20701 tatatgaaag cagcgttgcg tgcatttgga gatatgagca tcaaagtgaa atttatctct
    20761 gctattcgtc catttacatt ggaaccaacg gaagatggcg ttcaatttat tcagctgatt
    20821 actcctgtac gtacaaatta acaatgattt tcaatgttct tgaaaattta attgaaaaga
    20881 aatagaaaaa ataaaatttt aaacagaagg ccctaaaatc tcttttaagg ctttctgttt
    20941 atttttgttt aaatcacctt ttttagatta aatcgtctta tatggaaaaa tatatggata
    21001 aatttgtttt attgcgaaaa aaaaggtata atagagtata cttttaataa tgaaaatgag
    21061 ggatgggcat tgaaacaaca agtcattcta aatacggaat tcatgacgtt gggccaaatg
    21121 ttgaaagaag tcacagttat cggtagtggc ggacaagcaa aatggtattt ggcagaaaac
    21181 actgtgttag tcgatggcga accagaaaat cgtcgtggac gcaaacttta tcccggcatg
    21241 atggttgaag ttccagaagt aggaactttt tttatggtaa aaaaaggaaa cgacgataat
    21301 gaggctgaat aagctgtatt taaaaaatta tcgaaattac gaagagctga acatcgaatt
    21361 ttccaagaac ctcgtcatct ttttaggaga aaatgcgcaa ggaaaaacga atcttttgga
    21421 aagtatctac gtattagcta tgacgcgaag tcatcggaca agtagtgagc aggaattgat
    21481 tggctggact gacgatcagg cgatgattca aggagagatc acaaaaggtt catccactct
    21541 tccattagaa atcttattat ctaaaaaagg ccgaaaaacc aagatcaacc atatcgaaca
    21601 gaaaaagtta agtacttacg tgggacaaat gaatgtcatt ttatttgcac cagaagatct
    21661 ttctttagta aaaggcagcc cgcagaccag gcggaagttt ttagatatgg aattaggcca
    21721 gatcaatcca atctatcttt atgatcttgt ccaataccaa gcaattttga aacaaagaaa
    21781 ccagtacttg aagcaattga atgaaaaaaa acaaactgat ttgctttatt tggatatttt
    21841 gtccgaacaa ctagcagcgt ttggcagcaa agtattgaaa gcaagagcac agttcgtcaa
    21901 gcgattggag ttttgggcta attctttgca tcagcaaatc acccatcaaa aagagcagct
    21961 ggaaatcgag tatctcaccg cagtcgattc tttagaaaca catacgcaag agcaaatcca
    22021 agaacaattt ctcgcacttt tgaaccaaaa taaaaagaaa gacctttttc ggggaacaac
    22081 gacagttggt cctcatcgtg acgatctttc cttttttatt aatcagaaaa atgtgcagac
    22141 ttatggatcg caaggacagc aaagaacaac tgcactaagt gtcaaattag cagaaatcga
    22201 tttgattaaa gaagagacag gggaatatcc aatccttttg ttagatgatg tgatgagcga
    22261 gctggatgat aatcgtcaac tccatctgct agaaacaatc gaaggaaaag ttcaaacgtt
    22321 cttaacaaca acgacacttg accatgtaaa aaataaaatg actgttgaac ctgagatttt
    22381 ttatgttcaa caagggaaac taaaaggaga agaaactgaa tgacagaaga aagaagttta
    22441 gtagaacgcg ctaaagagta tgatgccagt cagattcaag tacttgaagg acttgaagcc
    22501 gttcgtaaac gacctggcat gtatatcggt tcgactagtt ctgagggtct gcatcacctt
    22561 gtttgggaaa ttgtcgataa ttcgatcgat gaagtattag caggttttgc aacgaaaatc
    22621 catgtgatta ttgaaaaaga caacagtatc accgttattg acgacggtcg ggggatacct
    22681 gtagatatcc aggcaaaaac tggacgtcct gcagttgaaa cggtctttac tgttttacat
    22741 gctggaggaa aattcggcgg tggtgggtac aaagtttctg gtggacttca cggagtagga
    22801 tcttctgttg ttaacgcgct ttctacacag cttgatgtca aagtatacaa agaaggaaat
    22861 gtgtactatc aagaatatcg tcgtggagct gtagtggacg acttaaagat tatcgaacaa
    22921 acggatcgcc atggaacaac ggttcacttt acgccagacc ctgaaatttt tacagagaca
    22981 actgagtttg atttttcaaa attggctacc cggatccgtg aacttgcttt cttgaaccgc
    23041 gggatgcgta tatcgattga agacaaacga gaagaagaac cagtcatcaa tgaataccat
    23101 tatgacggcg ggattaaaag ttatgtcgaa tacttgaatg caaacaaaac cgtgattttt
    23161 ccagaacctg tatatttgga aggtgaacag caagatatcg cagttgaagt ctctatgcaa
    23221 tatacagacg gctaccattc caatatcatg agttttgcca acaatatcca tacgtatgaa
    23281 ggcggaacac atgaatcagg attcaagact gctttaactc gtgtgataaa tgattatgcc
    23341 cgaaaacaaa agctgatgaa agaaaatgac gacaacttga ccggtgaaga cgtgcgagaa
    23401 ggattgacag ctgttatttc tatcaagcat cctgaccctc aattcgaagg acaaacaaaa
    23461 acaaaattgg gcaattccga agtacggaca gtcactgatc ggttatttag cgaacatttc
    23521 atgaaattct tgctggaaaa cccaagtgtg ggccgtcaaa ttgttgaaaa aggattacta
    23581 gcttccagag ctcgtctagc agcgaaacgt gcgcgtgaag taacgagacg taaaggtgct
    23641 ttagagatta gtaatctgcc aggaaaatta gcggactgct ctagcaacga tcctgaaaaa
    23701 tgcgaattgt tcatcgtcga aggagattcg gccggcggat cagctaagca aggtcgtaat
    23761 cgagagtttc aagccatctt gcctattcgt gggaaaatct tgaatgttga aaaagcaagc
    23821 atggacaaga tcttggcaaa tgaagagatc cggtctttat ttactgctat gggtacaggg
    23881 tttggagaag attttgatgt atcgaaagct cgctaccaca aattagttat catgactgat
    23941 gccgatgtcg acggcgcgca tatccgtaca ttgctgctga ctctttttta tcgttacatg
    24001 cgtcctattg ttgaagctgg atacgtctat attgctcagc cacctttata cggggtaaaa
    24061 caagggaaga atattacgta tgtacaacca ggaaaaaatg cagaagaaga gttgaaacaa
    24121 gtcgttgctt cacttcctgc ctcaccaaaa ccaagcgttc agcgttataa aggacttgga
    24181 gaaatggatg atcatcaact atgggaaaca actatggacc caagcaatcg gatgatggcc
    24241 cgcgtcagtg tggacgatgc tattgcagca gatcagatat ttgaaatgtt gatgggggat
    24301 cgagtagaac cccgtcgtgc attcatcgag gaaaatgcac actatgtgaa gaacttagat
    24361 atttaatcat gaaggaggaa aaagaatgag tgaagaaatc agagaaaaca tccatgatgt
    24421 caatctaacc agcgaaatga aagactcctt catcgattat gcgatgagtg ttattgtcgc
    24481 acgtgcactt cctgatgtca gagatggtct gaaacccgtt catcgccgta ttttatacgg
    24541 catgaacgaa ttaggtgtaa caccggataa agcccataaa aaatctgcca gaatcgtcgg
    24601 agatgtcatg ggtaaatacc atcctcatgg agactatgcg atctatgagt caatggtacg
    24661 gatggcacag ccattcagct accgttatat gctagtggat ggtcatggaa actttggttc
    24721 tgttgacggt gacggtgccg ccgctatgcg ttataccgaa gcacggatga gcaaaatcgc
    24781 tacagaaatg ctgcgtgata tcaataagaa cactgttgat ttccaaagca actatgatga
    24841 tacagaaaaa gaaccagttg tactacctgc tcgcttcccg aatcttttag tgaacggaac
    24901 aacggggatc gccgtaggta tggccacgaa tatcccacct cataacttgt ctgaggtagt
    24961 agcggctatc gatttgctga tggataatcc tgatgtgacg accaatgaat tgatggaagt
    25021 attacctgga ccagattttc caacaggtgg tttggttatg ggaaaatcag gaatccgaag
    25081 agcgtatgaa acaggtaagg gttctattac cgtacgtgca aaagttgaga ttactgagat
    25141 gccaaatggt aaagaacgga tcatcgtgac agaattgcct tatatggtca ataaagcaaa
    25201 attgatcgaa cggatttctg aactgcacag agacaagcgt atcgaaggga tcacagattt
    25261 gcgggacgaa tcttcccgtg aaggtatgcg gatcgtcatt gacatccgtc gtgacgccag
    25321 cgcatctgtt atcttgaata acttatataa attgacatcc ttgcaaaatt catttggatt
    25381 caatatgttg gcgatcgaaa aaggtgtgcc gaaagttttg agcttgaaac aaattcttga
    25441 aaactatatc gaacatcagc gcgaagtcat cacaagacgg acagtctttg aaaaagaaaa
    25501 agcagaagca agggcacaca ttttagaagg tttgcgtatt gctttggatc atatcgatga
    25561 aatcattgcg attatccgcg ggtctaaatc agatgacgaa gcaaaagcga cgatgatcga
    25621 acggttcgat ttatccgatc gccagtctca agctatttta gatatgcgtt tacgccgatt
    25681 gaccggtttg gaacgggaaa aaatcgaaaa tgaataccaa gaactcttaa aactgattga
    25741 agatttaact gacattctgg caagaccaga acgtgttaca gaaatcatca agaatgaatt
    25801 agcagacttg aatcaacgat ttggtgataa acgacgcaca gaattactag tcggtgaggt
    25861 cttaagtctg gaagatgaag atttaatcga agaagaagaa atcgttatta cattgacaaa
    25921 caatggttac atcaaacgtt tggcaaataa tgaattcaga gctcaacgaa ggggtggacg
    25981 tggtgtccaa ggaatgggta tccacaatga cgacttcgtc aaaaatctgg tttcttgttc
    26041 tacccatgat acattgttat tctttacgaa taacggaaaa gtgtatcggg caaaaggata
    26101 cgaaattcca gaatacgggc gcacagccaa aggaatacca attatcaatt tactaggtat
    26161 cgattcgagt gaaagcatcc aggcaatcat tgcggtgacg ggagaagcag aagaaggcca
    26221 ctatctcttc tttacgacgc gtcaaggtac agtaaaacgt acttctgtca ctgcttttgc
    26281 taacatccga agtaatggtc tgatcgcaat tggtttgaaa gaagacgatg agctcgtcaa
    26341 tgtgctactg acagatggtc aatctaatat cattattgga acacataacg gctactctgt
    26401 cactttcaaa gaagaagcag tccgcgatat gggacgtaca gcttccgggg ttagaggaat
    26461 acgcctgcgt gaggaagatt atgtcgttgg ggcagcctta atgaaggaag atcaagaagt
    26521 attagtgatc acagaaaaag gttacggaaa acggacaaaa gtatcggaat atccagtgaa
    26581 aggccgcgga ggtaaaggga tcaaaacggc gaacatcact gaaaaaaatg gtccactagc
    26641 tggattgacc actgtttctg gagatgaaga catcatgctg attacagata aaggtgtcat
    26701 tatccgtttc aacgtatcga ctgtttctca aactggacgt tcaacattag gcgtacgttt
    26761 gatgaagatg gaagctgata cgaaagttgt cacgatggca gcagtcgaac cagaagctgc
    26821 agaacaaaca gttgaagaac aaggatcaga agaatagcca tcaagactaa ttgtgtaagc
    26881 tagcaagaat gaccgattaa aaaatctggt tattcctgct ggcttttttg attagttgaa
    26941 tttctcttaa aatattcgaa actgttcatt ctgtattgct tttgaccaaa atagagtgta
    27001 taatcagagc ttgtgagtag tctaattaat tagataactc tccttgctct taggaaccta
    27061 agagccgaaa gtccacaggg aggtgaatat caatggaaaa cacgaaatat gaaatcatgt
    27121 acattattcg tccaaacatt gatgaagaag caaaaactgc tttaatcgaa cgtttcgatg
    27181 caatcttgaa agataacgga gcagaagtta tcgaatcaaa agattgggaa aaacgccgtt
    27241 tcgcttatga aatgaacggt taccgtgaag gtatctatca catcgttaaa gtatcttctc
    27301 catcatcagc aaatgctgtc aatgaatttg accgtcttgc taaaatcaac gacgatatca
    27361 ttcgtcacat gattgttaaa gaagaagctt aattgttgtt tcatgtgaaa caatagaaaa
    27421 cgatgagagg agatgactat tttgattaat aatgttgtat tagttggacg tctgacgaaa
    27481 gatccagatt tgcgttacac agcaagtggt acggcagtcg caacatttac tttggctgtg
    27541 aatcgtaatt ttacaaacca aagcggcaat cgcgaggctg attttatcaa ctgtgtgatt
    27601 tggcgcaaat cagcagaaac tttagcaaac tatgctcgta aaggaacact tttaggtgtt
    27661 actggacgta tccaaactcg ttcttatgat aatcagcaag gacaacgtgt atacgtgaca
    27721 gaagtagtag ctgacaactt ccaattgctg gaaagtcgtt ctgcatctga aaatcgccaa
    27781 caaagcggcg gattccaaag ttctggtcaa tcagctggcg gatttggcgg aaacaataac
    27841 tctaatcaaa catctcaatc atccaacggt atgcctgatt tcgaccgtga tacttctgac
    27901 ccattcggct caagttcaac gatcgacatt tcagacgatg atttaccatt ctaaacgaat
    27961 ttgataggag ggaaatagaa tggcacaaca aagaagaggc ggacgtaaac gtcgtaaagt
    28021 agactacatt gctgctaacc atattgaata tatcgattat aaagatatcg aattactaaa
    28081 aagatttatt tcagaacgcg gtaaaatctt gccacgtcgt gtaactggta caggcgctaa
    28141 aaaccaacgt aaaattactg ttgcaatcaa acgcgctcgt atcatgggct tgctaccttt
    28201 cgttagcgaa gactaataaa tcctaggaat tgaatgactg atccttttga tcagctattc
    28261 aattcctttt tttctgtaaa aataacctct attcgtttag tcgctcgaat gacgaaagtt
    28321 atggtaaaat caaattagtc atatatggga ggaaaattat ggaaaataaa aacaatcatt
    28381 tatccccgaa acctctcttc cttatcctgt ttatattaat cgaagtattg gtagtcttaa
    28441 ttttaccatt tcgttttgtt agcgcttcgg tcattctatt gatgaattta tggggtgttc
    28501 gctattggtt gaaaatgaaa cgttggctta ttttaaataa acgtgaaaaa atccagcagg
    28561 cttcgactgt agctgaaacc aatctagctt atgtctcaga agtcatgcct gtaggagtga
    28621 ttgcttatca gccatcaagc caaaaaatcg aatggctcaa tccattagca ttgaaaatca
    28681 aagatcaaag tggattaaca gaggaagaat tgctagatac tttttttact gcaaaagaaa
    28741 aaaagaaaaa ccaagtctat ctagcagata aaacatttca gtttgatatg gatacagtaa
    28801 agggtgttgt ttattttaat gatattaccc aaaaccagtt gttaaaactc catcagacga
    28861 acagtcagcc ggtgattggt attttatcta ttgataacta tgcagatgcc attgataaat
    28921 tggatgacaa agagatttct tatttgaact ctttcgtcac tacactagtt tctgactgga
    28981 tgaatgaata ccatgtcttt ttcaaaagaa tcaacgcaga acggtttttc ttcgtagcac
    29041 agatgatcga tctgaaaaag atgatggata aaaaatttga tttgctggat cgctttcgag
    29101 cagaagctga aaaacagagc tcgcctatca cccttagtat ggggattgct tatggctcaa
    29161 gaaccctcga tgaaatcggt ggagaagctc agaataattt agatgttgct ttagtccgtg
    29221 gaggcgacca agttgtcgtg aaagaggtaa aagaaggagc aaaacctgtt tattatgggg
    29281 ggaaatctgc taagaatgtc aaacgcacgc gtgttcgttc tcgagcgatg agtaccgctt
    29341 tgcgtcggat ttttgatgaa acaggcgatg tgtttatcat ggggcacaag tttccggata
    29401 tggatgcttt aggctctgct tttggtgtca gttgtctggc acgcttcaac cagaaaaaag
    29461 cttacatcgt tatcaacgag aacgagatca ttccagatgt agaacggtgt cttgaagaaa
    29521 tccataagca tcctgaatta gaaatgcaac taatctctcc agaacgtgcc atagagctga
    29581 aaaaagaaga ggacctcctc gtgatggtgg attaccataa accttctcta tcgatctctc
    29641 agggcctata tgagcaattt gataagattg tgatcattga tcaccatcgt cgtggggaag
    29701 agtttccaag taaacctctg ctgacttata tcgaatcttc agcttcttca gcttcagagc
    29761 tagtttctga gctgatccaa taccaaagca gcaaaacaaa tcgcttagat cgttttgagg
    29821 ccacattatt gcttgcaggg atggttgtag atacaaatag tttcaatgtc cgtacaactg
    29881 cacgaacttt tgacgttgcc agctatttaa ggtcttgtgg agcagacgca tccttagtac
    29941 aatatttatt gagctcggat ttagcgacat acttggagat cagcaatttg attgctggaa
    30001 gcgactatgt gacttctgat attgttgtgg cggcagggac agacgaaaaa gagtataata
    30061 gtgttatagc agcaaaaaca gcagatacat tgctttcgat gatcaatatc aatgcagctt
    30121 tcgtcattac aaagcggaca gacggcttga ttgggatcag tgccagaagt accggcacga
    30181 tcaacgtcca aatcatcatg gaatccttag gtggcggagg acacttcaca aacgcagcta
    30241 ctcaactgga aaatacgaca gttgaggaaa caaaacagaa gctatttgct gcaatcaaag
    30301 aaaatatgaa tcaaatatat gataaggagt aatccaaatg aaagtaattt ttttacaaga
    30361 tgtaaaagga aaaggtaaaa aaggggacat caaagaagtt ccagcaggtt atgcacaaaa
    30421 ttatctaatc aaaaataact tggcaaaaga agcaacgaaa agcagtatca gtcagttagc
    30481 aggacaaaag aaagcacaag aaaaacacga agctgaaatc ttggaagaag ctaaaaagtt
    30541 aaaagaattc ttggaaaaag aagatactgt agtcgaattg aaggcgaaag caggggaaga
    30601 cagccgtttg tttggttcga tcccttcaaa acaaattgct gaagggttaa acaaacaata
    30661 caaaatcaaa ttagataaac gaaaaatcga attagaaaat ccgatccgtt cactaggcta
    30721 cacaaacgta cctgttaagc ttcatcatga ggtgacggct acgatcaaag ttcatgtcgt
    30781 acaagaataa caaatcttga tagcgatgtt cagctggtaa gtataaccag aaggaaaaaa
    30841 gacaaaccga aatttatctg agaaaacagc tgcagcaatg aaagcaaaag ctgcaaatcg
    30901 atttcagatt gatttcggtt tcttttttgg gaacagcaaa atagcataaa gaaaacgagt
    30961 ataataaaag agaactattt ttttattaca ctttcggtac gaatgatgac ttttctctca
    31021 ttttcttgta aaatgaagca attgaagaca aggagcgata cgtatgaatg aagtgtggca
    31081 ggatcgaatc ccaccgcaaa atattgaagc tgaacaagcg gttttaggct ctgtttttct
    31141 tgacgcagaa acgatcattg atgccatgga gtacatagag ccaaaagact tttatcgtcg
    31201 tggccatcaa attatttttg agacaatgat cgagttaaat gatcgtaatg aagcgattga
    31261 cgtggttact gtcaaagacc ggctggaaca agccaatttg ttagaagatg ccggtggttt
    31321 aagttatctc tcagacttgg cattagcagt tccgacagca gcaaatatcg tctactatgc
    31381 gaaaatcgtt gaagaaaaat cattgctgcg tacattgatc cagacagcaa caggaatcgt
    31441 tacgaaagga ttcgagcaag gagaagaagt tcaaacaatt ttagatgatg ccgaacgcag
    31501 tatcttggag gtttcggaaa aaagaaatcg aagcggcttt ttatctattg ctgaagtact
    31561 gaactccacg attgaaaata tcgatcgact agctcaaaac aatgaagaaa tcacaggtct
    31621 accaactggc tatcaaggtc tggataaaat gacagcaggt ttccagcccg aagaactaat
    31681 cattcttgct gcacgtccag cggtaggtaa aacagcgttt gcattgaata ttgctcaaaa
    31741 tgtaggaaca aaaacagatc gttctgttgc gatatttagt ttggaaatgg gggcagaatc
    31801 tcttgtaaat cggatgcttt gtgcagaagg ttcgattgag gccagccatt tacgtacagg
    31861 tcagctttcg gaagaagaat ggtcgaatct gatcgttgcg atggggagtc tttctcgagc
    31921 aaatattttt atcgatgata caccagggat caaaatctct gaaatccgtg cgaaatgtcg
    31981 gaaactagcg caagaaaaag gcaatctagg cttgatattg atcgattatt tgcagttgat
    32041 tgaaggtaac ggtaaagaga accgtcaaca agaagtatca gatatctctc gccaactgaa
    32101 aaaactggcg aaagagctga aagtacctgt cattgctctt tcacagttat ctcgtggagt
    32161 agaacagcga caagacaaac gaccagtgct aagtgatatt cgtgaatccg gatcaattga
    32221 acaagatgcg gacatcgtag ccttcttgta tcgagatgat tattatgaaa gagaaggcgg
    32281 agatgacgat gatggaaacg agccaaaaaa tgacaacgtc atcgaagtca tcatcgagaa
    32341 gaaccgaagc ggtgcacgag gaacagttga actactgttt atcaaagaat acaataagtt
    32401 ttcgtcgctt tcgccaagag aagaatttta aagaagaggt tgtgagcctt gagcaatccc
    32461 gagagctctc gtaagaagat gcaaggagta accgcaggaa cgactagagt acttaattta
    32521 aacagatctc caaagggatt gtgacaaaag tcttgtcaca gtcccttttt ccgaataaac
    32581 ggtgttcaat cagctgaccc ttggtattag ctcagcaaac gtcaaaatat gaggaactat
    32641 tttgacgttt gtttctctaa tactcaggtc aaaacgctga tcttacgacc tcttttcctt
    32701 aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca atatcatcaa acatgagaag
    32761 cagttttttg aaattgctcc ttgtgactca gagttaaacg gcaggctcac aacctctttc
    32821 ttaaacggtg ttcaaaagct tgcatctgcg gtaatacgcc caatcaaacg aaaaatatga
    32881 gaagctattt ttgtttggct gttcttatta cttgatgcag gacagctttt tcacaacctc
    32941 tgattcacgg tgttccaaaa gtagcttctt cgaaaaataa gtcgaaattt cacaaaaatt
    33001 tgagaagcaa ttttcgtaca ttccttctta tttcttgaag ctgaccactt ctgttacaac
    33061 ctctttttta ataaccattc taaaaagata aagttcgttt tttaagcgtt tttataaaat
    33121 aaaaataaaa atcattcgat tttatttgaa atatgtatct attattgata caatggttca
    33181 ggattaaata atatagaacg aggtgttcac atgtcatctg tagtagtagt aggtacgcaa
    33241 tggggcgatg aagggaaagg aaaaatcaca gactttctca gtgaaaatgc tgaagtgatt
    33301 gcacggtacc aaggtggcga caatgcaggg cacacaatta agtttaacgg tgtgacttat
    33361 aaactgcatt tgattccttc tgggattttt tataaagaca agatcagtgt gatcggaaac
    33421 ggcgttgtag tcaatcctaa atcattggtt aaagaattag cttatttaca tgaaaaaggt
    33481 gtagaaacaa gtaatttgcg tatttctgac cgcgcgcacg taatcttgcc ttatcatatc
    33541 aaattggacc aattacaaga agatgctaag ggcgaaaata agattggtac aacgattaaa
    33601 ggaatcggac ctgcctatat ggataaagca gctcgtgtag gtatccgtat tgcagactta
    33661 ttagataaag aaatttttga agaacgtctt cgtttgaatc tagatgacaa aaaccgtcaa
    33721 tttgtaaaaa tgtttgattc agaaccactt gattttgacg atatttttga agaatattat
    33781 gaatacggac aacaaatcaa acaatacgtc acagatactt ccgttatctt gaatgatgct
    33841 ttggatgcag gcaaacgcgt gttgtttgaa ggcgcacaag gtgtaatgct ggatatcgac
    33901 cagggaactt atccttttgt tacttcttct aacccagtag ccggtggggt aacaatcgga
    33961 agcggtgtag ggccttcaaa aatcaataaa gttgtcggcg tctgcaaagc ctatacgtca
    34021 cgtgtcggtg atggaccatt tccaactgaa ttatttgatg aaacaggaga acaaatccgc
    34081 gaagtaggac gagaatacgg tacgacaact ggtcgtccgc gtcgtgtagg ctggtttgat
    34141 tctgtagtta tgcgccattc taaacgagtt tcaggtatta ccaacctatc tttaaactcg
    34201 atcgatgtat taagtggatt ggaaacagta aaaatttgta cggcttatga attagatggc
    34261 gaactaatct accactatcc agcaagcttg aaagagttga accgctgcaa accaatctat
    34321 gaagaattgc caggctggtc agaagacatt acaggatgca aaacacttgc agaactgcca
    34381 gaaaacgcac gtaactatgt acgtcgtatc tcagagcttg ttggtgtacg tatctcaaca
    34441 ttttctgtcg gacctgatag aacacaaaca aacatcttag aaagcgtctg ggcgcaaatc
    34501 taaggataaa aacgacgact gaatcaggac gttcttacca gagcgagtcg aagtgtttat
    34561 ctatacgata ataataactt gaacactgtt tattcagaat aagggactgt gacaaaaacc
    34621 gtgtcacagt ccctttttcc gaacaaacgg tgttcaaaag cttgcatcta cggcactaag
    34681 cccaatcaga tgaaaaatat ggagtgctat ttttatctga ttgttcttac tgcttgatgc
    34741 agagcagctt tttcacaacc tctccactaa acggtgttct cctgccaact cctcggtcac
    34801 aagtcacaat attcaacaaa catgagaagc tgttttttga aattgttcct tgtgactcgg
    34861 agctaaacgg caggctcaca acctcttggt aaacggtgtt caatcagctg accctcggta
    34921 ttagctcaaa aaacggcaaa atatgaggaa ctattttttc cgtttttttc tctaatactc
    34981 aggtcaaaac gctgatttca caacctctga ttcacggtgt tccagaagta gcttctacgg
    35041 aaataagccg aaatttcaca aaaatttgag aagcaatttt cgtaaattcc ttcttatttc
    35101 ttgaagctga ccacttctgt cacaacctct tattttgatt agaacttgcg aaaataaacc
    35161 ggttaaagtg tgtctagcgc aagagatttg ctataataga cgataagggt aaaatgtaac
    35221 gagaaggggt tgaaaaatgt gtatcaaatt gtaacagatt cttgttgtga tctgccatac
    35281 catgtattag caaaagaaaa agttgatttt ttatcaatga atctccaatt gaatgatcaa
    35341 gagttagtag atgacctcgg aaagacattc aattatgacc gctacatgaa tcagctgaaa
    35401 aatggtgcga tgcctacgac atcacaaatc aatgttggcc gatatttaga atttttccgt
    35461 tcttatgcgg aaaaacagat tcctgtttta tatgtggctt tttccagtgg attaagcggc
    35521 tcttacagta gtgcgcttca agcggttgaa ttgctgaagg aagaatatga agaccctgag
    35581 atctatgttt ttgatacaaa agctgcaagt attggggaag ggcttttagt attggaagct
    35641 gtaagattga aaaaagaagg taaaagcatc gaagaaaccc tagagtggct ggaaagtaat
    35701 tatttgaaag tccattcatg ggtaacagta gacgatctga aatatctaga acgaggcggt
    35761 aggatttcca aagcaagtgc tactcttggc agtctattga gtgtaaagcc tattattacg
    35821 gtggataaag aaggaaggct gacgaatgtt gacaaagttc gaggaagaaa caagtcgatc
    35881 cagacaatcg tcaatgagac ggtaaaaaca atcgttgcac cacttgatca aatcgtttat
    35941 gtggcttacg ctggggatct agagagcgcg gagaaggcaa aacggctttt ggaagagcag
    36001 ataaagatga aagatgtgaa gctttatccc ttaggaccaa cgatcgccag tcacacaggc
    36061 tatggctgta tcgcgatttt ttcgatggga atcagtcgat aaaagcagta actcattctg
    36121 taaaaaagcc cagaaattga ttgtaacaaa aacagcgact cttaaaagat agatgagcat
    36181 cctatctctt agaggtcgct gtttttttat tttttaagct aaataggcca ttatgcccat
    36241 aactcgttca attgtttttg aatatctgca ttttccaaaa attcatcata tgtcgtatca
    36301 gctcgatcga tcacaccttt atccgaaacg gcaatgatgc ggtttgccaa tgtttggata
    36361 aattgatggt catgtgacgc aaataagatt gagccagtaa atgccatcaa gccgtcattc
    36421 aatgctgtga ttgattctaa gtctaaatgg ttcgttggat catctaatac aagtacgtta
    36481 gctttcgaaa gcatcatttt tgaaagcatg caacggactt tctctccacc agataaaaca
    36541 ttcactggtt tcaatacttc ttcaccagaa aacaacattc ttcctaagaa gcttcttaag
    36601 aaggtgttat catcttcttc tttacttgca tattgacgca accagtctaa aatcgttaga
    36661 tcagtatcga attctttcgt tgtatccttt ggtaaataag aattacttgt tgtcacaccc
    36721 caacgtactg ttccagtatc tggcgtaatt tcacccatga taactttgaa tagcgttgtt
    36781 gttgttatat cattttctgc gacgaaagcg accttgtctt ctttgctcaa attaaaagat
    36841 atatcatcta aaattttctt tccatcaatc gttacactta cattttctac ctgcaataag
    36901 tcgtttccaa tctcacgttc aggtttgaat ccaacgaatg gataacgtct agaagaaggt
    36961 tggatatcgt ctaaagtaat tttttcaagc atttttttac gtgaagttgc ttgttttgat
    37021 tttgatgcat tcgcactaaa gcgggcaata aattcttgga gttctttgat ttgttcttct
    37081 tttttggcat ttgcgtttgc ttgaagttta gccgctagtt gactagattc caaccaaaaa
    37141 tcataatttc ctacataaag tttgatttta ccaaaatcta gatccgccat atgtgtacat
    37201 actttgttca aaaagtgacg gtcatgggat acaacgatca cagtattttc aaaattgatc
    37261 aaaaattctt ccagccaatt gatcgattgg atatccagac cgtttgttgg ttcgtctagc
    37321 aaaagaacat caggtttacc aaatagtgtt tgtgctaata acacttttac cttttgtcca
    37381 ccagttaatt cactcatttg ctgatggtgc aattcttcag ggatgttcag accttgcagt
    37441 aaaacagctg cttctggttc agcttcccat ccattaagct cagcaaattc tccttctaat
    37501 tcagctgctc gaataccatc ttcgtcagtg aaatcctctt tcatgtaaat cgcatctttt
    37561 tctttcagca cttcatacag acgcttgtgt cccatgatga ctgtttcaag tacagtatag
    37621 tcttcatagt cgtaatggtt ctgtttcaat acggccatcc gttcatctgg tcccatagta
    37681 acggaacctg tggaaggctg cagatcccct gataacactt taaggaacgt tgatttacct
    37741 gcaccatttg caccaatcaa gccatagcag tttccggggg taaatttaat attcacatca
    37801 tcaaatagtt tgcggtctga aaagtgcaaa ctcacatcat ttacagtaat caattttttt
    37861 cctcactttt atcattatta gttttgacaa gtcttataga attatatagg ggaaaggtaa
    37921 aagattcaag gcaatcgaac attctttgtg tttcacgtga aacagaatga aaaaaataaa
    37981 aataaaagcg gagcgaaaat agctactata ggatttatta gtttgcaaca gcataatttt
    38041 tgacgttatt tataagaggg agtactataa aactgtaaaa gaaatgaaag aaggattgaa
    38101 aatggatgaa aaaagaacca tcgactgggg ctcattgatt ttgggaattt tatttgtact
    38161 tgtctcattg ttatcatttc aagaccctgt cggaaattta gttgcaattg tagtagtctt
    38221 tgcgattttt gcctttatta aagggatatt tgaactgttt gtacggaaca gattaaaaga
    38281 gctaacagga tataaaggaa agatgccctt aataatcggg atcatcgata ttctagttgg
    38341 cgtctttttc ttattcaata ttggtgcagg agtcgcagca ttgccttttg tttttgcagt
    38401 atggtttatt gctgattcag ttttagcgtt atttactgct gacttggcaa gaggagtaag
    38461 tgaaggatat tattggttta cgatcatcgt caatatttta ggaattttat taggaatttt
    38521 cttattgttt aatccaattt cttctgcgtt gacattaagc tttttagttg gattctattt
    38581 tatgttattt ggtatcacac atatcgtcta tgcatttaga taagtaaaat caaacaaata
    38641 aaaaagccgg cttccgatta cagttttact gttgtaattg gaagccggct tttttatcat
    38701 ggacaaatat gcacgaggtg atttttaggt gtcgagacaa atttatgcaa aaatgtgaga
    38761 agctatatac acaaatttta tcttaatact cgaagcatag cgcagttgtc acaacctctt
    38821 ttcatataat tcattcaata ctggcaaatc atggacttca tatttttctt tgaatgcttg
    38881 gatttcttct tcagaatatt ttcttggatc taaatgcaga tcttctactg gcaatgggcg
    38941 cttgttattg atcttcacat cgattactac aggacgatct gattttgcag ctgcatcaaa
    39001 ggcaaatcga agttgcgagt attctgtgac tgtaaagcta tttgccccga gcgcttctcc
    39061 aactttaccg aaatctgcat cttctaaaaa tacaccaaat ttcttttgtt ccgtatcttc
    39121 ttgttctgct tcgatgaaac caaaagaatc attcgaaaag acaacattaa taattggaag
    39181 ctgatatttg acttgtgtaa tgatatcttg catgaccata gcaaacccgc catcaccact
    39241 taaggtaaat acttgttttt ctgggtagct tagttgtgcg gcaattcctc ctggcacacc
    39301 attacccata gttgcgaacc atccagatgt cgtatgtttt tgtttaccgt tcatattcaa
    39361 taaacgaata gaatggatag tcgtgttacc gacatctgtg acgaaaatcg catcgtcttc
    39421 agcaatacga ttgatttctt tatagacagc ctctggacga atcggttctt cctctcgatc
    39481 ttcaaaagat ttcaaccaat ttacccattt ttctttattt tcttgatttg ctaggtacca
    39541 gctatcagca gggcgagcat cccctaactc gacaagtctt tgcaaagctg tgtttgcatc
    39601 accgaggatc gacaaagatg tttcatggcg tcgtccaaat tttgacgcat cgatatcgat
    39661 ttggataaat tcagcagttg gattaaaaaa tgcacgtcca aatgggaagt cgctaccgac
    39721 aaataagatc agatcggctt ctgccaatgc ttcatttccg ggtttagtag cgacacgtcc
    39781 agcaaaacca agaaagtttt cataatcatc aggaataatt ccttttgcta gaacggaagc
    39841 gacaacagga actgaaaaat gttctgagaa ttctttgatt tgcggaaatc cgtttcgcgt
    39901 tccttgacca acataaagaa ctggtttttt tgctttttca agataaggca aagcagctag
    39961 caaatctttt tcttctggta atatcacact tgttttgtga gtgtgagcgg tggagaaagg
    40021 ttgttcgtca atttcttcaa aaccaagatc aacagggata gtcacgatag ccacgccttt
    40081 atgctcatag gcggctttaa tggcttcatc tactacatgc ggaagacttt gtggtgtcat
    40141 gactgtacga ttgtatacgc taacatctgc gaaaatagga ttttcattta gttcctggaa
    40201 agagttatag ttcatggatg tagaagcaac ttgtcctaag aacgctacta gaggcacatg
    40261 gtccatctgt gcatcataca aaccattgat caaatgtgtc gcaccaggtc ctgcagagcc
    40321 gaagacagcg ccgactttcc ccgttaattt tgcatctgca gcggctgcga gtgcgccgac
    40381 ttcttcatga cgaacttgaa tgtagttgat ttcggttttt tcttgatata gcgcatccat
    40441 aattgaattg aaagatcctc cgggaatgcc gtaaatatgg tcgatacccc agctttcaag
    40501 aacttttacc attgcgattc ctgcattgat ttttgacatg gtgtttcact cctttagcaa
    40561 tgatgataca taaatttttt gtatctagag tatagaactt tttatcgaaa atcccaacta
    40621 attcgtcttt tcacaaaaat gtagtcatgt ttttgggaat atgctagagt agtacataga
    40681 tagattcaag agaggggaat ggcatggttg aatggctatt gagacttgaa ccttggcagc
    40741 aagcacttgc tgggacagct tttacttatt ttatgacagc tcttggtgcc gggttggttt
    40801 ttttctttaa agaaatcaaa aaagaagtgc taaacttgat gttaggattt gcttctggtg
    40861 tcatgattgc tgcaagtttt tggtctttgt tagatccggc tattacaaaa gcagaagaaa
    40921 atggagatat tgcttggcta gttgtaagta ttgggtttgg tttaggcggt gtgtttttat
    40981 atatggcaga taaaacactg ccccatatgc attttggacc acaacatgaa gcagaaggat
    41041 tgcctaccca tttaaaacgg acgatcttgc ttgttttttc tattacattg cataacattc
    41101 ctgaaggttt agccgtgggg gtagcattcg gtgcagcagc aactgcggat aatccgacag
    41161 ccgctatatt agccgctgtt tcggtggcgc taggtattgg tatccaaaac ttcccagaag
    41221 gagcagctgt atcaatcccg ttgcgacaag aaggtctgag tcgtaaaaag gcctttgttt
    41281 acggacaagc ttctggaatc gttgaaccaa ttgctggagt gattggagcg ctactagtaa
    41341 cgaaagtgga gctgctgctt ccttatgcac ttgcttttgc cgcaggagca atgatttatg
    41401 tcgtggtgga agaattgatc cctgaagcac agcagacatt gtccagcaaa cgtcattttg
    41461 cagtttttgg cgtcatgagt ggatttatca ttatgatgat tttggatgtg gcattaggat
    41521 aaataaaaaa aatatatatg atatatcaaa tagggccgcg aacttatatc gcgaccctat
    41581 ttttttagta agttatatca taatgaagtg aatggtatca tacattaata atagtttttt
    41641 ctatgtgtat ttcctttgat ccagcgaaca agccagatga taagtgcgat tgggattaga
    41701 actttgaccg caaaccataa aagcccgctt aggacactga caaaaagact gatgacgaag
    41761 ctagctgcaa ttagcactaa aagaaccatg aagatattta agaacatatt tttttgacgc
    41821 atacaaaacc ctcctcttgt tcattcttta ctatagaaaa agtataacag ggattgttta
    41881 aaaacacctc caactgaaga ctgattttta cttcatctac ttaaatgatc aaacaattgc
    41941 tttttctctg gtttatcatc taaaatagag cggaaaagga ggagaatatc atgcctaaaa
    42001 atcgtcttga agcatttaca gatgctgtaa tcgcgattat catgactatt ttagttttag
    42061 aacttcatga acctaacgga gacacgtggg aggcgctcgc tgcattaggt taccgatttt
    42121 ttatctatat tgtcagtttt atcattttag cgatttattg gaacaatcat catcatttat
    42181 ttcaagttgt acataagata aatggacggg tcttatgggc gaacagtttc tttgtttttg
    42241 cgctttcgct ttttccgttt gcaacttcat ggatcagtga gtacatcaat agcctggctc
    42301 cagaaatgac ttatggtttt gttaccttga ccgctaatat tgcgtattat atcttggcaa
    42361 aagaacttgt caaagcaaat aaaggccacg agaaagcatt gaaggcgatg ttgaataatt
    42421 acaagaaatc gtatctatcg attggtttga atgtgttagg aattgtctta gggtatttag
    42481 tagcgccagt agccgtgctg atcgcaaaca tcgtgattct agctgcttgg atcatcccaa
    42541 gtcgtaccat cgaatcacaa tatcggtaaa atgatccgtg tttaaaattt aagagaaaaa
    42601 tatagaaaaa ataaataaac gatcaaatat ccgagtgata ctagtattca aagagggatg
    42661 cagatggatc aaaaaagaat tcatgtagga ctgattacta gttttgtcac gatgcttatt
    42721 tatttggatc aaggtcattt gacttggaca gtagttggtg tcgtaggatt tttgacatta
    42781 ttcacagcaa taaaaaaata aacatcttta tgtaatctga tgttctatct atttaagaaa
    42841 agcatgttta cagcagtatg attctgttgt aaacgtgttt ttatttgtgg aaaatttaat
    42901 ttttagaaaa gtgtatcgaa aaatagatag ttagtttttc cacagtggat aacttcgtaa
    42961 gagataaaaa taaaaaatta gtcaaagaag ggcgtataga tttcttttga taggagatat
    43021 acaacagaaa tgaataaata ttaacgtgtt ttcaaacagt ataaaacggt gtggtttttg
    43081 gaataaaaaa ataacatatc tcattttacg cttttgttat tttatactta aaaaataacg
    43141 acacagaaaa taccgtgtct cagatttctc tactacttct aaaaactact gtttttttcc
    43201 tttgaaatgc cttcaaaaag taggatcagg cagaatatac tggcagaatc aaggagaagg
    43261 gagcctaaat aaggagaaaa accatagaaa atataaagta attacttata aaacaagctt
    43321 tttatagaaa aataatatac ctgagtaggg tataaattaa gacggaattc ctttctagat
    43381 tgagatattg actaggaaga atgttaagat tttaagcctt taagctaaaa aaaaaccctt
    43441 tttgttaaat aaggggaata tagcctgtca gtttcaaact gcaagtcgtc ctgctgcaat
    43501 aatatagtag attagagatg aaaatagatt tttttaaacc aatgactgaa taaaaagacc
    43561 gtcatagata cacattggaa tgtgtctatt acggtctttt tttacgaacg attttattga
    43621 agacggacag ttcgggtcaa aaataaaaaa gctacgatca gaaataagaa taaaatgtat
    43681 cccaaaataa tggctagacg gtctaactta tttgtcgata gatgtttgtt tagaagttga
    43741 taggcccata aacctatcag tcctcctgtt gtattagtta tcaaatcagt gatgtccgct
    43801 acgccaatac cgaataggaa ttgaatcaat tctgccaaga agcttacaag gaaaataatc
    43861 cctaattttt tagaaaaaga aagtctcttg aaattgacat tcaaaagcac cccaaaagga
    43921 aaaaagacaa tcaagttata agtggtctca cgtaataccg tcgtattttc aaaagaaaaa
    43981 gtagaaaaag ggacgagatt gacattgctg taagaataag tgagaaattg tggaagatta
    44041 aatgatagct tgaataaaat caaccataat agaaagaata aataaatccc taataaaaat
    44101 tttgatacat accgcataga catctcctcc atttaaaaag tataccatcg aaaaccgctg
    44161 aaaaatcata aaaaagtatg aagtttaagg accaacgtag ttatcgtacg aaaattagaa
    44221 gctttttttt gttgggaatc cggtttcttt aacaaagcta agatagcgag ttgcttggaa
    44281 aagttgctat cttttttctg tcaaaacgac tcggaatgtt cgttttttgt tctaatttct
    44341 ccaagttgtt tactttttga tactaagttt atgaaaaatc aagaaatagt tgttatacta
    44401 ggtaatgctg acaaacggga ttggcatttc atcttggttc agcttttttt ccaattacta
    44461 ggaaggaggg atagattgtt caagacttat tttcgtttca ataaaataca agataatcct
    44521 tttcgtatca tgaatctgat gctacttatc tttattgtat tatggttagg ttacataaat
    44581 catgattttt tgatttcaag tttttcatca ttagggatct ttactttttt ctattatcaa
    44641 aacataccga tgaaatattt gctgaaacgt atgtttctga tcggttgcgg actgttggtt
    44701 gctttcgttt tggggatctt atcgacttat gttttatggc ttgaaccatt tgccgtagct
    44761 ttggttgctt tttccagcag attcgtgttg cgattattcc atatttctaa accaggtggc
    44821 ttgttttttg cgatgctttc tgccatggga acgagcatgc agctgccaat cgctcaatta
    44881 ccgatcgtct cactttattt ttttatgggt gtcgtttttg ccctgattgc ggcagtgatt
    44941 acaaaattac tggattcacg gcctgagcag acaattgaaa aagcaacttt aaaagaaaga
    45001 tttcacgaag agcctttagt gatcattgat tctgttttct acagcgctgc cttatttctt
    45061 tccgtttatg tcagtcacgg cttgaatctg cataatcctt attggttgac cttgtcatgt
    45121 gcatcgattt tgctagcaga aaacttggat gcgatgaagc atcgacaagt ccaatatctg
    45181 attggatcga tgggtgggtt atgtgtgtcg gcattcttgt catttgtgcc gtttacgcag
    45241 ttgcagacca tttttctgat cacttttcta tatggaatcg cacaatttct agttgctaga
    45301 aattatgcag ttgctaatat ttttcttaat ccgatggcgt tgatgctatc tacacttatt
    45361 cgtggagcat acttgatttc tttgatcgaa tatcgttttt tagggatcgt cataggaagt
    45421 ttcatcggtt taggtgttgc gtgggtaatg acggttggtt tgcaacatta tttaacggtt
    45481 gttcgtcaaa aattagaata gaaggacaaa tatatgtgcc aaaagaggtt atgacaagat
    45541 ttttgtcaca acctctaatt caaggtgttc aaaagccaga ttctcagcat taagtcaaat
    45601 tcacacaaaa atgtggaaag gaactttcaa aaaaatttta tatttattct atcaaaaaat
    45661 tttatattta ttctatcaaa aaattttgtt tatgatggta actgaataaa ctttcctgag
    45721 atggtcaatg ctttccttga aagtcttaca gatattcttt cttcatagaa agtttaagtt
    45781 ttatagttag tgtacaataa aagtatgttt ataccatatg gtgtccggat aatcagtcat
    45841 ttaaacaatg aggttcaaag atatgaaaag gggaaatttg atgaagaaaa taagcaatga
    45901 aatccaaatt ctggcagaaa ctttaactct tcccaaagtc gttatagagc aaatgattgt
    45961 acaagcaaaa aacatccttg atgaggtgtt tgagcaatat agtcatgaac taatggatcc
    46021 taataaagca aaggcgactg caaagaaaat agacaaagtc tatgaagagg aaccttttgc
    46081 agcattagct atttatctat atgcagcttc tcaaagttgg aaaaaaattt atcaaccatt
    46141 gaagattcca agaactatct atttggcaac aatgaatgct tttactagat ttattcatga
    46201 acatttccaa gtaacaggaa gctatcgctt tgaccgtggt ttttggattt ggcattacac
    46261 tagtggcttg atctttcgga ttggtgaatt ggagtacgaa atgacatatt ttccgaaagg
    46321 gtacacggat ctaagattag aaggaaagca gtgcctttct cttcatattc cttccgatgc
    46381 agatttatct cagaataaga taagagatag ttacgaaagt gccattcgtt tttttgaact
    46441 ttattttcct gattaccatt accaagtgat gtacacagat acttggttac tatcacccaa
    46501 tcttactaaa tggttgaaaa aagagtcaaa aatctgtctt tttgcagccg attatcgatt
    46561 attatcagtt gatgaacagg acgatagtgg agtcccttgg atctttggac gagtagatgc
    46621 ccaaatacat gattatccag aaagtacgag tttacagcga caagcaaaag agcaattgct
    46681 tgcaggcgag cacattggct ctggcttagg tattcttact tcataagttt agtacttcga
    46741 aatagtttaa aagagcgtga gacaaaagta aagaacactt ttgtctcacg ctctaaacac
    46801 gtataaacgg cggaagcaga agcaactcct tcggaaataa gctgaaattc acaaaaattt
    46861 gaaaagcaat tttcgtgaat ttcttcttat ttcttggagt taaacgcttc tgtcccagcc
    46921 tcttttttag tgttctatcg aacacacagt acgttcaata ggtaaactag ctataacaat
    46981 agatattaaa gttaacggac aagagggcct tttttaggta gctaaaacgt aataatgaaa
    47041 atttatttcc agagatagga gtcaatcagc tagtctgatc gactgtttta acaagttgac
    47101 tttcatttta acttttgata ccatttaaaa cacaaatcgt aattgtttcg atttgtgttt
    47161 tttagcatga ctacaatcaa agaagaaagt gggtcgtcca tatggaaaaa acagatatct
    47221 caagtgcata ccgccgcttg aaaagcccaa atatcaaaac acgaaaacgt gcgctgaaga
    47281 tcatcaaaga tgtgaaacgg aatagtggga aaaggtaaga agaaggaaac ttaattaaaa
    47341 aaatagccga aaaacgtttt tcggctattt tcaataatcg gtttttgtgt aaggtttccg
    47401 aaagaactgc tgttgatttt ccatttttaa catatgataa attggtagaa tctttctttt
    47461 caaattgata ccattcccta attccagtta tatagttaac tacagaacca caaagcacgt
    47521 acgtttataa aagtattatc tgtagttatt tttcaattcc ctttcaacct cttattttga
    47581 ccagtagtat tgatcacttt accttttaac acctttgttc gtttttgaaa catttttagt
    47641 caagaatgga aacgtaacta cataatcaaa ggttttgcga aatatttcat gaaatatttc
    47701 atgtagaagc gagcaatacg gttgcaaata accattatcg tttaataagc agttacgaaa
    47761 gctcccaata tctctaacgt tcagctcact ccatttcttt tcttcaaaaa aatcagtgat
    47821 tcgtatctct ttctatttgt cgaaaaagtt aactttaaaa agtaacgccg aaaaaatatg
    47881 caaaaaaata aaaaagcagt tactattgct agaataacat caaggaataa taagttttgg
    47941 ttttcagata atagtcgata agttgtgtat tggaatttta gatacagtaa taaagtattt
    48001 ttcatgaaat tttgtgagaa tcactattac aagtatcttt aataaaatta atggttaagg
    48061 aggaacttaa agtagaatgt aaatgaatag ttgtagtcag tcgattgtga tactagactc
    48121 aaagttgcag gaataagttt ttcaatttgt gattggaaga taaaaaatga aaaagaaggg
    48181 ctttttttta tactttgttg attgtagtgt ttattttccc tctgtttagc caagtaacat
    48241 tttctatgac tcaaccagtt tcaagtgagg aacatgataa cctttttcgt gctacagaag
    48301 agtttaagaa atatcaggaa aatattgttc cggagactcc attagctagt gagccaatta
    48361 ctgatattga tggaaaccaa ataggatggt atatacagta cgaagttatg gtggtaaata
    48421 atgactcaat agtaaaaaat acagtaggct tagagctaac accgattgaa aaggtgagtt
    48481 cattgttaac gtatatttat actgatgaaa gtgacgagac tgagatcatt ttaacggatt
    48541 actcaaaaat tgctactgat aaaaagtata tattgtggat gtagacacta gtgaaatact
    48601 ttatgatata gaaattgatg aaaatttact agatgtagca caagaaatcg atcatcaaaa
    48661 gcaggaagct attcgatatg ctggtagaaa agggaaaaga aaatatttat tacgtgaatg
    48721 tagcaaaagt tagagaagat gaaaatgagt ggaaagaatt caagagtcgc tactcaatta
    48781 actcgactcc gacatttaca gtttacagag aaggatcgat agaaaaaact gttttttgga
    48841 ctaaagaaag tggaatgtct ttagctgaag tagaagagtt tttggattat gttagtatgc
    48901 aacagtaagg gagttcttat tatgaaaaat tttgacacat attatgttat tgttttttcg
    48961 atatctttgc tgttaatatt actaacttta atgcagtata aagagtatcc agagtatttt
    49021 attttaactt ttgtatattt agtaagtagc tacacacttc tatataaatt cagaagttct
    49081 tctagagttt ctaaagtttg tttcttaatt agcttattga ttctataata tttttgattt
    49141 atataggaaa ttaaaaatat tatagaatca acactcagag aacgggttgg tttttaatag
    49201 atttaataag tactgataat gaaatttctc ctggttggga aaacgaagtt ggttaccctg
    49261 tagaagaatt ttttcaagat tactttgcgg agtatgccga taggataatg agagattacg
    49321 taacagataa aactcaagaa gtcatcaatc aatcccagtc attaaatgaa ttatctgata
    49381 aggcgaaaga agaagcagtt gccattattt cttcagggat tagtgactat attgatatga
    49441 gtggtgaaat caattatggc gataaagaca aaattgtacg catgataaaa gcttttatca
    49501 aaacttttga tgtgaaggca gatcttaagt ttaatgatac ttacctagta ggaaaattaa
    49561 ttaatatcct tgggacagag aaagatacgg aaacgtttat ttcctctttg tctatgttgt
    49621 ttacagataa gcatttttca actcagcttg gtggagagga actagtggaa atcttttaac
    49681 cattacgccc agcattaata aaagtatatc aaaaaagtac tcctgatgat ttttaagatt
    49741 ggtttgagaa ataatgtgaa aacactattt ttaatgttaa ttatagatag agatgaacgc
    49801 gtcatatggt taaaagaatg aaaaagtcaa agatacactg ctatatttca ctaaggatat
    49861 agcagtgtat ctttcatgtc gtttcactgg cagtttttta taaaaggagg tgtgcatttc
    49921 agttgctttt ctttggtagt tagttgaatc gtttaagaat taacggatgt ggcagacagg
    49981 tgctctgtcc aaaaaccagt aaaatctttg atggttccat ctttatttag ctgtgcctgt
    50041 tcaaatactg ttttgttttt accgaatgga tcaattgcaa taattgttcc gatccccgca
    50101 cgtttggcag caagtaatcc tgagtaagca tcttcgataa caagacaatc agccggagct
    50161 aagctcagtt tgtctgccgc tttaagaaaa atatccggtt gcggtttccc agggaaagag
    50221 ccgtcgtcat agacaatctt gtcccagtca aaccagcggg ctaaatcgaa aatatcaaaa
    50281 taaaaagcaa cattctcttt gacagtagcc gtggcaatcg ttaatggaat ctgttggtca
    50341 gtcagctggt caagagtcgc ttcaagccct tttgtcaact gaagctcgtt ttcattttgc
    50401 aagcaaagca tacgataata gctttctttt tcttctgaca atacggcgat ctcagaggcg
    50461 gtcaaatgct ctgaaatgaa atgtttcaaa atctccgtat tcgtccgacc atgaatattt
    50521 tttaaaatat cctcgtctga taaaccatct tttgtatgat catgtatcat atgcagccaa
    50581 gcagcttcat gcagatgaga gtccaaaaac attgttccgt tgaaatcaaa tataatccct
    50641 ttcatagtta cgctcctata gtggtatttt cggttgaatc agcaatttgc agatcgacat
    50701 attgtgcata gtgctcttga acctcccgcg agatctggcg atccgtaatg agcagatcga
    50761 aatcatgcaa attataaaac acataaaaat catctcgatt gaatttttta ttatcaacga
    50821 gtagatattt cttacgggaa ttatttagag cgatctgctg tgcttctcct tcttcggtac
    50881 tgtaagtaga gatcgcttcg ttgtgaacgc catttgaact gataaatgct tttgtaaact
    50941 ttagtcttct taaattgtcg ttggtgatcg gtccgacaaa tgcgccggta tttttccgga
    51001 aatcaccgcc aatcagtaga atttctggtc catctgcttg agcaagaata tcaaaaactg
    51061 gataattatt tgtaatgatc cgaattttct tgttcagtaa atgcgtcgcc aatagttcga
    51121 ttgttgtacc tggtcctaag aaaatcgttt ctccctcgtg aatcaaggag gctgctgtgg
    51181 cagcaatttc ttttttttct tgaatctgca gagtggcttt ttcagtgtga gaaagttctt
    51241 gatctaaagt gtaggaaaga ctttgagccc ctccatggac acgcagcagc ttgcccgatt
    51301 tttctaattc atctaaatct ctgcgaacgg tcatatcaga aacatctaat tgattgatga
    51361 tttcattaac ggtaaggatt ccttttttat tgaccatttc tacgatagta agcaatcttt
    51421 cttttttcaa cattgtcttc acctctaatt taaggataat ctatcatata aacggacaac
    51481 agtcaatcta attcgaacaa aagtaaacat ttagggtggt ttttatgttt gttacaatag
    51541 attttattgc tgttttctgg tttttatgat tatttgtgtt tgtttttgtt gacaaatgtt
    51601 ttggatgcgt ttacaatgca atcagttaga aagagcgaaa actgattata gatttgagga
    51661 gagatgtaca tgcttaaatt accagaagat tttatttttg gcggagccac agcagcctat
    51721 caggttgaag gagccactaa ggaaggtggc aaaggcgctg ttgcttggga tgacttttta
    51781 gaggaacaag ggcgattcag tcccgatccg gcaagtgatt tttatcatca atatgcaaag
    51841 gacattgaat tgtgtgaacg ttttggtgta aatggtctaa gattatccat tgcttggagc
    51901 cgcatttttc ctgatggagc tgggaaacca aatccagaag gaatcgcttt ttatcatcgt
    51961 gtgttcgaag aatgtaagaa aagaaacgta acgccgtttg tgacgttgca tcattttgat
    52021 acccctaaac gtttgtttga ccatggagat tttttgaatc gagaaacaat agaagcattt
    52081 gtttcctatg ccattttttg ttttcatgaa ttcaaagaag tcaaggtgtg gagtaccttt
    52141 aatgaaatct atccagttgc aaccaatcaa tatttgttag gtgttttccc accaggaatc
    52201 aaatatgatt ttacaaagat cgtcgcctgt cttcataata tgatggttgc tcatgcccgt
    52261 gtagtgaact atttcaaaga aaacgaactt ccgggtgaaa ttggtgtagt tcactcatta
    52321 gagacgaaat atgcggcaac agacgcgccg gaagataagc atgctgcctt tttagacgat
    52381 gcattgtcga tccgtttctt attagatgct acctatttag gctattattc aactgaaacc
    52441 ttgactgctc ttgatgagat atgtgaagca aatcaggcca gctatcattt tcctgaagaa
    52501 gatttcgttg aattgaaaaa agcatccacg cgtaatgact acttagggat caatcactac
    52561 caatgccatt ttgtcaaagc ttacgatgga gaaaatgcaa tccatcataa cggtacgggt
    52621 gaaaaaggga cctctgttta taaagtgaag ggaatcggag aacgtattta taaagaagga
    52681 attcctcgaa ctgattggga ctggctgatt tatccagaag gtctatatga cttgttgctg
    52741 cgaattaaaa gcgattaccc acattacaac aaaatctata tcactgagaa cgggatgggg
    52801 tataaagatc agtttgaaga tggcattatt atggatcagc cgagaatcga ctatttgaga
    52861 gtctatttgg aatccttaag caaggcgata acagccgggg taaatgtgaa ggggtatttt
    52921 ttgtggtcgc ttatggatct tttctcatgg acaaatgggt ataacaaaag gtatggcttg
    52981 ttttatgttg attttgaaac ccagaagcgt tacccaaaag aatcagctta ctggtacaag
    53041 ttggtcagtg aaaccaaaac gattatttaa taagtgataa tggaggaaga aaagatgaat
    53101 aaagaggaat tacaaatgct tggttttgag atcgttgcat attcaggcga cgctcgcagt
    53161 acattattga aattattgaa agaagtaaga caaggaaact ttgaacatgt tgattcggcg
    53221 ttgaaagaag ccgacgaaaa tttaaccctt gcacataatt cgcaaacaaa aattttagcg
    53281 gaagaagcat ctgggaaaga gatggagatg ggattcattt ttatccatgg gcaggatcat
    53341 ttaatgacca ctttattgct gagagatctg attcaagact ttattgtact gtacagacag
    53401 aatcaaggat aggagaagaa cgctatggat ggaatcatta aacaaatcga aaaagggaaa
    53461 ccattttttg aaaaaatctc acgtaatagt tatttaggag ccgttcgtga cggattttta
    53521 acagcgatgc cagctatttt attttcaagc attttcattt tgattgctgc ggttcctgag
    53581 atttttggtt accaatggcc tgaatctgtc tccacatggc tatggaaagt ctataattat
    53641 tcgatgggtg ttgtagggtt actcgtttca gcaaccactg ctcgctgctt ggctgattcg
    53701 atgaatcgtc gcttaccgaa aaacaaagta atcaacacca cctctgtgat gctggcctct
    53761 gtggtaagtt tcctgttgtt aagcgtctct ccgattgaag gtggattttc aacggaatat
    53821 atggggacaa agggactact ggcttccttt gtcgctgcat ttttaacagt taatttatat
    53881 aagttttgtg tgctgaaaga tattaccatt aaaatgccta aagaagttcc tggaacgatt
    53941 tcgcaaacct tccgagatat ttttcctttc tctttttcag tatttgcggc cgttttaatt
    54001 gatttaggca ttcgacaaat cttccaaatc tcatttgcag aagcaatcat tacggtgctg
    54061 cagccgctat ttacagcagc tgacgggtac ttaggaatcg ctattatctg gggagcgatg
    54121 gcgctgtttt ggtttgtcgg tgttcatgga ccgtcgatcg tggagccggc aattgcggca
    54181 attatctatg ccaatgtgga aaccaatctg caattgttca attccggtga acaagcttct
    54241 aaagtactga cggtgggttt agggaatttt gtaggaacta tgggaggaac tggggcaaca
    54301 ttggttgttc cttttatctt cctactcttt gctaagtcta agcagttgaa ggcagttggg
    54361 aaagcttcct ttattccagt aagtttcgct gtcaacgaac cattgctatt tgcggcaccc
    54421 atgattttga acccttattt ttttattcca tttttgttaa cacctgttgt aaacgtttgc
    54481 ctgttcaagt tttttgtcga tgtattgggc atgaacagct ttatgtacgt tttgccttgg
    54541 gcaactccag caccgatcgg tttggttcta ggaacgggca tgggtatctt agcttttgtt
    54601 ctagcagcgg ttctaatcgt cgttgacttc ctgatctatc taccattttg caaagcatac
    54661 gatgctgtct tagtagagaa agaagcacaa aaagcagagg tgatcgcaac cgaggaaggt
    54721 gcttctgccg atgtacgtga ggaagtacct gtggcagcga gtcaagttat cagcgatgca
    54781 aataaagaaa tcaatgtgtt ggtactttgt gctggcgcag ggacaagtgc gatgttagct
    54841 aatgctttaa aaaaaggtgc atctgaatcg aaagcaccga tcagtgcaat ggcgggtgct
    54901 tatggttctc attacgaaat gctgcaggat tttgatatgg tggtcttagc accgcaagtc
    54961 aattcttact atgatgatat caaagaagac accgatcgct taggaatcaa gctggttgcg
    55021 acaaaaggag cagaatatat cggattaacg agagatcctg aaaaagctgt tcagtttatt
    55081 ctgaaccaat ttcaataaag gaggagccat aatgaaaatg ggaatttggt tgcgtaaagc
    55141 tgttttattt gcagctgtgt taggggcttt gggggctgtt tcaaaaactg ttgaagcatc
    55201 tgccagcgaa tttattcgcg gagcagatat ttcgatcctg tcagatatgg aaaaatctgg
    55261 tgcaaaatat tatgaagacg atatttcaaa agatgcctta gagattttaa aaaataatgg
    55321 tgtcaactat gttcgactgc gtttgtggca ggatccttat aatagtaatg gagaaagtta
    55381 tggagcaggg acaaatgatc tggaaacgac gattgacctt gcaaaacgag caaaaaatct
    55441 gggacttaag gtgctgctgg attttcacta cagtgatttt tgggttgatc ctgggaaaca
    55501 gaatcttcct aaagcatggc aaggtctgac ctttgaagaa atgaatacgg cattgtacga
    55561 ctatacaaag aacgttctgt cggaaatgaa gcagctggac gtttatcctg atatggttca
    55621 gatcggcaat gaactgaata gcggaatgct ctggccttat ggcaagtctt ggggagaagg
    55681 cgggggagaa tttgatcgat tggctgcttt tttgaagtct ggtatccaag ctgttcgaga
    55741 cactcaacct aaaacaactc cagtaatgct ccacttagct gatggtggcg atacaggagc
    55801 atttacttgg tggtttgatg aaatcacgag tcgaggtgtg tcatttgatt taattggagt
    55861 gtcgtattat ccgtattggc acggttcaat gaatgaactt caaaccaata tgaatgcgat
    55921 cagccaacgg tatggtaaag aagtgatcgt agttgaaaca gcttatgggc atacaacagc
    55981 gaatgccgat actatgccaa atgcttttgg tgaagccgaa gcagctgcgg ggggatatga
    56041 accaacaccg acaggacaag cagagtattt gctggatctt gccgatcgga ttcaggcagt
    56101 accgaataat cgcggggcgg gcttcttcta ttgggaacct ctttggtaca acggaaatgt
    56161 gagttgggca acacaagcag gtatgaatta tctcagtgtt caatccacta tgggaaacga
    56221 atgggacaac caagcgatgt ttgattttgc tggaaacgcc ttgccaagct tgcgtgcgtt
    56281 taaacaagca ggggcgcaaa taaatctagt taaaaatgca agtttcgaaa gcgatggacc
    56341 aacgaccagt ccttccaatt ggcaaacctg gtttcaacaa ggaaccgcta agggtacgat
    56401 caaaacggaa gcgggcactt tttttgggga ctacaaacta actttttggc aggatcaagc
    56461 atacgaggca tcagcttatc aaaatgttag tggcataagc aaaggaactt acacattgag
    56521 tgcctatgta atgtctgggg gagagtttga tactaatcag ttatatatca aaaattatgg
    56581 tggagcggaa ctaaatactg cggttgttaa aacaagtgaa tggacaaaaa ttacaatcaa
    56641 agacattcca attacaacag gtgtttgtga aattggggtt tatagcaagg cttcaggaaa
    56701 tgcttggacg aacgttgatt ttgtttcatt ggtgaaacaa tagactgcgg atcgtttcga
    56761 ttcaagatcg gaggttccct tcagccacat cgttagcgta gaaggcagga atcgaacctg
    56821 cacctcgcct ttgccaaaaa taaccagaaa cgatttccag tcatttttac caaaacgagt
    56881 aaagcaccag acttcatcta cactttgtat tatgctaaag agagttcaac gatttcgtaa
    56941 gaagcaatga aaaaattgca aaaagttgtg cagataacat aaagtttgtt taagaaaggg
    57001 taaccttaga attccgtcgt gaatatgatt tgagcactta gatggataga aaaaagttct
    57061 cggaaaacag ttcgtttttc gagaacttct ttttatgata agaatgaaac aaattaactt
    57121 atattatagt ctcttttggt agggaaccat cttattttta atgaaaatca agcattttag
    57181 ctattgaaga atgttgattt atagggattc cccctccata ttatgttggc tctttattcc
    57241 cactctgttt tcaacgtaaa gtgtataaaa cagaatgcga tactatcaag ggagttaaaa
    57301 caatatacag aacagtaaaa cactataaat aaaaataaaa gtgcaataaa agtgcaattt
    57361 ttgcacctaa tcatactctg tttatatatg aaaactagat tctgaatcca atatttggtt
    57421 aacgagaggc gttcgaattt gaacgtcttt tatatattac tttcaaataa atatgaggta
    57481 gaatactatc tattttcttt ttaacccaat tgttataatg gagagtgtaa aatattttgt
    57541 gtaaatagaa aaaaggaagt cccttctgta gaatagagtt accacaacac attcacagaa
    57601 gagaggactt ccctatgaac gattttacta cagaaattct aaagactcta gcgaacaaag
    57661 gcgatttgaa tgaattattc cgtgtccatt tggagaaagc agtcaatacg cttctcaaaa
    57721 cggagttaac ggctttccta gattacgaaa agtatgatcg cattggtttt aacacgggta
    57781 attctcgtaa cggctcctat gaccgtacgg tcaagaccga gtatggggaa cttcatctcc
    57841 agattccgcg cgaccgcaat ggtgagttca agcaacagac tgttcctgct tatagacgga
    57901 cgaatgacac gttagaggag accgtcattc acctcttccg aaaaggtatt accatgtcgg
    57961 aaatcgcaga cttgattgag aaaatgtatg ggcattacta cacgccccaa accatgtcca
    58021 atataacaaa atcatttaca gaagaggtaa cggcgtttaa tgggcgggag cttcatgacc
    58081 gttatgctgc tatttatatg gacgcaacgt atattccgtt aaagcggaaa accgtcgcca
    58141 aggaagctat tcatatcgca gttggcattc gcccggacgg atcaaaggaa gtattgagct
    58201 atgcgattgc accgactgaa tccatcacga tttgggagga aattttattg gaccttcaag
    58261 agcgcggttt gaaaaatgtc ctcctgttca tcacggatgg cttaaagggg atggtaggag
    58321 cgattagtcg gttctatccc aaagctcgtt ttcaacattg ttgtgtacac gtttcccgta
    58381 atatcagtca taaagtgcgt gtcgatgatc gtaaggaagt ctgtgatgat tttaaaatgg
    58441 tgtatcaagc ctcatctaaa gaggtggcgt tggaagcacg tggtactttt gcggaaaaat
    58501 ggaaaaccag ctatccaaaa gtggttgaat cgattctttc gaacgatcac ttgctcactt
    58561 tctatgattt ccccttggcc atacgcaaga gtatttattc tacgaacttg attgaatcct
    58621 ttaataaaca aatcaagaaa tacagccacc gcaaggaaca gttccaaaat gaagagtcga
    58681 tggaacgttt cttagtctcg tcttttgata cttacaacca aaaattccta ggtcgcagtc
    58741 ataaaggttt ccaacaggcc gaaggcgagc tcgaacaaat gctaagccaa ctgattgaga
    58801 attagaaaca atctgcagta gggaagaatc atttacacaa aattattgac gctcccttat
    58861 aatgagaact tttactaaca taatttatga taaacttact atataatcat attaattaaa
    58921 tagttaggag atctgcttat gtttatatct actcttcaaa ttcgaaattt tagaaattat
    58981 gaatccgaaa tctttcgatt cgataatgag acaaatacta ttataggtga gaatgattca
    59041 gggaaaacca atgctcttac tgcattgaga atcttattag atgatagtta ttactatagt
    59101 agtaaaacac taaaagaatc agattttttt catggaattc aaaatgggtg gcaagggcat
    59161 tggattatta tctctgcgac atttgaagga atcagcgaag aagaatttga caatgagatt
    59221 tgtgcttcca tttctttaaa ttctgaaagt caaacaatct tagaagaatt gatttcaaat
    59281 gcagataaag gtgtaggtag tatttctcta tttattagac ctaacaaagc tattagaaag
    59341 caattatttg atatttccac tgaattagac tctcatcaat ttaacgaatt tagaaattct
    59401 attcgtctat ccgactatga attttactac acatctaaat caaatctaaa tttctgtatc
    59461 aatgaaaatt atgataaatt ggtaggaaga ctcaatgaca atatagctag taatcctgaa
    59521 gaagacgatg aagctctgtt gggctcaaga attgacatgt cagatatttt caagcatatt
    59581 tcggttgttt atgttgacgc tcttcgagat gttcttagag aaatgaaaaa caatcgaaac
    59641 ccagtcaaaa gaatcatgga aacaattgaa tcaaaaatat catcagataa tgttgagtca
    59701 ttaaaaacaa ttatacagca attaaatgag actattacca gtgttcctga aattaggaaa
    59761 attggcgaaa atattaatcg gcaactaaat agcataattg gttcagtgta ttctcctaat
    59821 cttcttcttt cctcaactat gtcagatgat atgggttctt tagcaaaatt tctttcaatg
    59881 aagccagaac aaaatatcga cttagactta ctagggttag gacatctaaa tatgatttat
    59941 ttagctttga aaatagtcga atttgaagcg tgtcgttcaa gagaactact taatattatg
    60001 ttgattgaag aaccagaagc tcatattcat catcatattc aaaaaactct gttcgaagga
    60061 ttaaatcttc aaaaaaacta tactcagatt ctcatgacca cacattctgt acatttagct
    60121 gaagtgtctg aaatatctcg gatgaatgta ttaaaatcgt ttaatggcaa atctatcgtt
    60181 atgaatccag caaataatct gaactcattt gctaaagaaa agttaaaaaa gaacaatcta
    60241 aatctaataa acgcagtaga gagatattta gatgttaaaa gaaatggatt gcttttttct
    60301 aaaggtgtta tcttagttga aggagatgct gaagaaatac ttattcctca aatagtaaaa
    60361 aaattatttg gtataaactt agacgaactt ggaataggtt tgattaatgt tggtagtact
    60421 tcgtttgaat atatcgctag cttgtttgac gatgatagaa tacagagaaa gtgtgctatt
    60481 gtaactgatt tagatgaaca ggcaatccca tcagaacatc gattgtataa aagcactgca
    60541 caagagaaag gtcaagcaag aaaagaaaaa ttatcctccc tttttaatga aaacaattgg
    60601 gttaattgtt tttatgctaa tacaacattt gaaattgagt ttttagatgt gaataaagaa
    60661 aatattctaa cttatgtcag tccaattata gatgacgcat tcaaagataa aaaaacaata
    60721 actgcttata aagaagaaat acaaagtgaa caatatttag aaagaaattt agcgatgtta
    60781 aaactagcca atcatgttgg taaggggtgg tttgcaattg agttaggtga aaaaattgac
    60841 tttttaatca aaattcctaa gtatattctt aatgctattg cttttgcatg tcaggaaata
    60901 gtagatctct caatttataa aaaaattcta ctccatacaa tcgacttgta cgaggaaact
    60961 acagaattgt cagctttatc agctagttta aaaacaagtg atacagctga tttgaatata
    61021 gcaataattt ctttattaga gtactttggt aaagatgagg atgttgtgta tctaatcaat
    61081 cagatagaaa attacacaaa aatactttat gctgaggttt caaaatgaca aatatcttcg
    61141 aaaaaatcgt aaatgattta aatttagaac aaaaagatgt tgtggaaagt gaagataacc
    61201 tttatgtaaa tgcatgtcct gggagtggga aaacaagggt acttacaagg aaaattgctt
    61261 accaagcaat taaacacgat ggatcactaa aaagaataat tgctatcaca tacactaata
    61321 gagctgctga agaaattaag gaacgcctaa gtttacttag tatagatgat gatattaata
    61381 tttgggtggg gacaatacat cagttttgtc ttgaatttat tatttatcct tttaaaatga
    61441 atctctcaag agtatcaaaa ggatttacaa ttattgatga ttatactcaa agagcttacg
    61501 tcagccaaat taataatatg ctgaatttaa atctcaaaac gtatgaactg aacaaaattg
    61561 atttgtcact ttctcatgat tttaaaatta atgaagttca gtatactcaa gtttctgaaa
    61621 tgtatcacac tatgttggaa aaaaataaag aaattgattt tgatatgatt ttactagtag
    61681 cgtataaaat tttaactgta aacagtaacg ttgcacgtaa tattgctagt aatataaggg
    61741 cgatttatgt ggatgaattt caagatacta gagaattaca atacaatgta atagctaaat
    61801 tacttcaaaa caaccctcaa attcagtcaa tgtttgttgg agatattgac caagcaattt
    61861 atggatcatt agatggtata gctaaatcag ttgaagaact agaaatgcta actagtcaca
    61921 cttttcaatc aaagacgcta catggctgtt acaggtctaa tcagagatta gtagacttct
    61981 actctaattt tcagagttgt ccttacgaga ttgaaagcag agggaataat aaaaacgacc
    62041 gtggttttat aagttatgat tgcaaagtta ctaaggagga tttacccaac ataataaaaa
    62101 atataataaa ggaaaagatt gaaagcggca ttcatgaaaa agatatttgt gtacttgctc
    62161 ctcaacacta tcctctgttt tcactgggtg agtatttaaa gaaagaatta ccgtattgca
    62221 attttgatgc tataaatata tcaccaatta aggtaaataa tcatagttta tttttcaagt
    62281 tagcaatttt gtactttact gaatcaggtg aaaaggttcg aagaagaaag ctaattgcaa
    62341 acgatatttt aattatatta aaaaatgaat ttggaataga agttaaagat tattttattg
    62401 acttagattt attacagcta ataaacagtg tgaaaagaat gtatagtgga gacgacaacg
    62461 gtgttgattt atacaaattt gttaccaaac atatatttgt taatcttaat attgacgaga
    62521 aaaattaccc gtctattttt aagcactatc tattttttat taacgaagta gaagatcgga
    62581 taaaaaataa ttcattatct agtagtgtat ctagttttaa gaagatgttt aaatctcgag
    62641 atggtatcac acttactaca gcacataaag ttaaaggaaa tgagtatgat actgttatcg
    62701 ctattaatct tctaaacggg aaaattcctc attggaatga aatttttaat gtttctgata
    62761 aaggaattag ttcagcgaga aaactactat acgtaatttg ttcaagagca aaaaataatt
    62821 tatttctttt ctcagaggtg ggttatttta cgagtaaagg agacttgctt tatcccactc
    62881 aattattaga taaaatagaa tttgattata atatttaaaa tacctaggta gtcgttgttt
    62941 taaatatagt aggaatcgga cgctcagtac ggagcgtcta tttttttacc caattttgaa
    63001 aggaagtgaa cttatgaaaa taaaaaatca agaatcaaaa ggtcgctctc ccccctttaa
    63061 aaccatcaca caaataagat tcattcaaac ataaaaacag aaaggatagg taaaaatatg
    63121 gaacttaaat atgtcattcc caatatggaa aaaacatttg gacaattaga atatgctggt
    63181 gaagggaaca ttgaacaacg tcgaataaat ggcagaccaa ccattctctc tcgtagttac
    63241 aatttatact caacgattca acgagcagat gatattgttg tcattcttcc ctccgaagct
    63301 ggcgagaaac attttgaatc cgacgaaaaa gtcaaactca tcaacccaca tattaccgca
    63361 gaaggttata aaattggcaa tcgaggattt accaattaca ttatgcacgc agacgatatg
    63421 gtgaaagcat aagaaaggaa aggtgaaaaa atatgagatt agcagaaggt attgtgattg
    63481 aaaaagacca gacatttggc acattgaaat tttccgcctt gcgtcgtgag gttcgtatcc
    63541 agaatgaaga tggtacggtt tccgaagaaa ttaaagaacg tacctatgac ttaaaatcaa
    63601 aaggacaagg acgcatgata caagtcagta tccccgcttc tgttcctttg aaagaatttg
    63661 actacaacgc agaagtggaa ttaatcaatc ctgtggcaga taccgtagcg acggctactt
    63721 ttcgaggggc agacgttgat tggtacgtga aagcagacga tcttgtatta aaaggacaga
    63781 caaaacctca tcagaaatat aaaaaagaag cgtccgaaag tgaaaaatag gtgttgctta
    63841 tgacaaacac accattgatt ttgaaagaaa ttccgaagga tgaagccatt tcttttattc
    63901 ggcaatacca ttattcaaag atactcccta gattgtgtaa atactttcta gggatttttt
    63961 cagaagaaaa attattaggc gttgtggaat taggctgggg tacgcaaccc ctacaaacca
    64021 tacgcaaact ctttcccgac agttcccttc aaaccacaga ttatttagaa attggaaaga
    64081 tgtgttttct tccagaaatg aatcaaacca attattttgg cagtcaagct ctttcagctc
    64141 taattaagtg gttgaaagaa catacggact gtcatttttt atatacactg gcagatggaa
    64201 ttgagggaaa atgtggctat gtctatcaag cgtccaactt cttttactgc gggtatttca
    64261 agacaagtgt ctatcgtgat aagcagtcat gggaaaagat acaccctcga agtgctcgcc
    64321 ttttattaga ggaaaatgct cgctttgaac aggtagagaa aaagcattgg ctttcccagg
    64381 cattttgcga atacaaaggg attgagaaaa tcaatggacg catgtttcgc tatctctatc
    64441 cgttgacaaa agaagcgaaa aaactgttag gacacactct ctatcgacgt cattattatc
    64501 cgaaagaaaa aaatttacgc tttgaaaagc gaatcgctta tcagaaatat gaagccattt
    64561 ctcaaccaac ttttgataaa caggctcgta tctacaatac acaattattt tgataggtgg
    64621 aaaggaggat ttttatgcca ttgcttcatg acagaggaga gcgaatcaaa gccaacgata
    64681 agcacttggt ctatcatttt gtactaattt cattgctggt agtttttcta gtcgtcctac
    64741 tcccttttca ttggagagcg ttacaatcgg tgaactggca agcagttcag ttagatacat
    64801 ttttctatca acttcatacg ccatactttt ggagcagtat tctcactgct ctttttgtat
    64861 gcggacttat cagctggctt tattatcact atcgtataga ttctataaaa cagttagagc
    64921 accgtcaaaa gttagctcgt atgattttag aaaatcattg gtatgaagcc gaagaaactc
    64981 aatcagaggg attctttaaa gatttaccca gcaagaaaac caaacaacga atccgccatt
    65041 ttcctaaaat atattatcga atgaaagatg gactaatcca tattcatgta gaaatcacct
    65101 tagggaaata tcaagatcag cttttgcacc tagaaaacaa actagaaaca ggattgtatt
    65161 gtgaattagt ggaaaaaacg ttgaaagatt cttatgtaga gtatgtccta ctttatgata
    65221 ctattggcaa tcgaattggc attgaagacg tggtagctca agatggacgt gtcaaattga
    65281 tggaatcggt ctattgggag ttcgattctc tccctcacat gttaattgct gggggcactg
    65341 gtagtggaaa atcctatttt attctcacat tgattgaatc tctcctgcat acaaatgcaa
    65401 agctttatat tcttgaccct aaaaatgctg atttggcaga cttaggggcg gtcatgaata
    65461 atgtctatta ccgtaaagaa gatatgttgg catgtatcaa tcaattttac gaagatatga
    65521 ttgatcgcag tgaaaccatg aaacaacacc ctaactataa aacaggagaa aattatgctt
    65581 atcttggttt gtctgccaat tttcttattt ttgatgaata tgtggcaatg atggatatgc
    65641 taggtcgtga aagtaccacc gttattcata aactcaaaca aattgtaatg ttaggacgac
    65701 aagcaggctt ctttttaatt cttgcctgtc aacgtccaga cgcaaaatat tttagtgatg
    65761 ggattcggga caactttaac ttccgtgtgg ctttgggtcg tatgtctgaa atgggctttg
    65821 gtatgatgtt cggaagcgat acacaaaaac aatttttctt aaaacccatc aagggaagag
    65881 gttacgtgga tacaggaaaa agtgtgatta gtgagtttta tacacccctt gtaccaaaaa
    65941 ggtacgattt cttaggagaa ataggaaaag tcattcaaaa aaagcaatct gagcctgtac
    66001 cgcacgaagt gaaaggtaca ggttcagact tgctttgatt ggtgtggcgt tagccacgcc
    66061 aatcctttag ccccctctat ctaacagggg ggcacaaata caactgaaaa caggcaattc
    66121 tcatcaacca atgttgatgg tacaaaggat tgcggaaaat atgaaaggtg taaactcaag
    66181 ggtcatagtt tacatctttt ttagattgga ggtttgcgaa tggaaaacga aaaaatttgg
    66241 attaaggaat tgaaagaaaa gcgactggct tatggcgttt ctcaaaataa actggcggtt
    66301 gcttctcata ttaccagacc ttacctatcg gatattgaaa caggcaaggc agtccctact
    66361 caacaggtga aagaagattt actgaacgct ttggaacgct tcaatcccga taacccattg
    66421 gagatgttat tcgactatgt acggattcga ttccctacca atgatgtggc tcaaattatc
    66481 ggtgaggttt tacgtttgaa tatggattat atgctacacg aagactttgg ctattattct
    66541 tatcccgaac actatcgttt cggtgatatt gttgtcctag tctctcatga tgtaagtaaa
    66601 ggtgttttat tagaactgaa aggaaaaggc tgtcggcaat ttgaaaactt tctattggct
    66661 caacatcgga gctggtatga tttctttcaa gattgcatgg aacataaagg tattttcaaa
    66721 cgcttggatt tagctatcaa cgataaaaca gggattttga atattccaga tttggcaaag
    66781 aaatgtaaac aggaagaatg catttccgtc tttcgaagct ttaaaaatta tcgcagtggt
    66841 gaattggttc accgtgatga aaaaccatac atgggaaaca cactttatat tggctcatta
    66901 aaaagtgaag tctatttctg tatatatgag aaagattatg agcaatacgt gaaaaatgat
    66961 gttcccttag aagacgcaga agtaaagaat cggtttgaaa ttcggttaaa aaatgaccga
    67021 gccacccaag ccatgaaaga tttattggca catcaacagg cggaaaaaac agcctttgaa
    67081 attatcaatc gctatatccg ctttgcagat aaagacgaca ctaaacgtcg gagtgattgg
    67141 aaaactaatg aacgttggga atggtttatc ggtaaaaatc gtggagcatt acgcctaacc
    67201 acacagccag agccttattc ttttgaacga acattgaact ggttacatca tcaagtcgcc
    67261 cctacattaa aaatcgcaag cattttagat gttctcaacg gtacaaccat tatctccacc
    67321 atgattcagg aagccaaact gacagaaaaa catgagaaat taattgaaca acaacatcta
    67381 gccatggagg atttgattac atgagccttt taacaaaaga attaaagaag ttagggtttc
    67441 agtgtggcat tgagtttcaa gcgtatatac aaaatacagg gaaatatacg tctctcatta
    67501 ttgagggaaa acggcaagct ggtgatacca tctataccta tgatttttac aaggtgagat
    67561 tttataataa ttataccaat cgagtaaccg tctatggaga gcatttaacc ccttttcaat
    67621 tattaaggcg tgtaaaaagc tatatctatt atcgagaaaa atatcttaag gaaaggagga
    67681 caatcacatg aattttgggc agaatttgta caactggttc ttggataatg cacagtcatt
    67741 ggtattgtta gcgattgttg tcattggact gtttttaggt tttaaacgag aattttcaaa
    67801 actcattggc ttcttgatta ttgctctaat cgccgtcgga cttgtgttca atgcagctgg
    67861 cgtgaaagat gtgttattaa acttatttaa ccgaatcatt ggtgcttaac agatattttt
    67921 catgataaaa taggaagtat atattttgtt atgaaaggat ttatgaatat gtttacaaat
    67981 gatcaattta aatctctttt aattaaaaca ttagaaagaa agagctcttc aaattattat
    68041 gaaggaggta acgagattgt ttctaaaatg aaaatatcag aggtaacttt agatgagact
    68101 gacgatttta cttattataa aggatataaa aagggctgga atacgctttg cacatatctt
    68161 aaaataagag ttccttttga tgatttagac ttttttgaaa gtcataaaga tttgattacc
    68221 cagacagcaa gctccatata tgataaacaa ggtgataatg tattagtgga tactatttta
    68281 gtaccacttc cagagaatta cgaagtaatt aactttagtc agttgaaaat tagtgatgtg
    68341 gtttcacaag ctattgaaga cgctgagtct tttatgagta atggtgaata tcaacgtgcc
    68401 tttgacagag ttcacactgc ttttcatgga tatttaattg aaatactaaa aaaatatgaa
    68461 attacagttc ctagagacga aaatctatct aaattatata gtaggataca acaattaatt
    68521 gaaaaagaaa ttcaacctac tgaacttgct gatatagtga agacaacgat aaggtcatca
    68581 aatggaatga ttagctctct taatgaagca agaaataggc attcacttgc acaccctaat
    68641 acaaatatta ttggaaagag agaagcaaaa ctaataatag gtatttcaag tacagttaca
    68701 gattatatta gcggatacct tgataagtag cgtcattaac tgattgctac tttttttatg
    68761 actattttta taaaaaggat gtgataagaa ttggaaatga aagtctatgt ggcaaattta
    68821 ggacggtata atgaaggtga attagtcgga gcatggttta ctccaccaat tgatgaggaa
    68881 gaaatggcag aaagaatcgg tttaaatgag gactacgaag aatatgcaat acatgatttt
    68941 gagcttcctt ttgatgtgga cgaatacacg ccgattagtg aaatcaaccg tctatgtgaa
    69001 gccattcaag aaatcgaagg tacacctatt tataatgaac tcaaagaaat tcaaggcatg
    69061 tggtttagta gcttggaaga attactggaa aacaaagagg atattcattg ttatagtgat
    69121 tgtgattcga tggaagatgt cgcccgttat tacgtggaag aaacaggaca gcttggtgaa
    69181 gtcccttcca atttacaaaa ttatattgac taccaatctt tgggacgtga tatggaaata
    69241 gagggtaatt acctagttac ctctcatggg gtatttgaat attgtcagta agtttaacaa
    69301 tccgtgttat aattaaatta ataaatagca cggagaggta taaattatgg taaatgtatt
    69361 tgaaaatctt aaactattaa aactagacat gaaagataaa ggctgggtga tagattcctt
    69421 ttactttcgt tacaaacagc aaaattatat tgtacttgtt aagctatttg aaaaagagga
    69481 aaaagttcca gaatatgctc tgttaaaact agaattttta aaggaaaacg atttttcaga
    69541 tatgctagct gtctatgcta attcggtaaa attatataca gacacgaaaa caataagaga
    69601 atattttggt atcgaataca gtagtaactt gggagatgtt ttatttcaat ttagccaaac
    69661 tcttgctcga tttattccga cagaagttag tgagaagaaa aatgaagacc aaaaagaagc
    69721 catgtgtttc tcattaagtc aaagtgattc agaagatccc agaaaaaaat attgtttttc
    69781 agttagaaga aatcctttaa agggaaatgg tgagctggga aaacgaagtc cttttaatga
    69841 caataaaacg agattgtata gacccagctt atatgaacga ttagggtcag ataccaattt
    69901 aagtttcaga tattcaatga atccagatga tgaagaaact gatgaaggta ttattgcaaa
    69961 atggacaaaa aataaaattg aatagttaaa gcattgaaag agcaatcacc tattttgatt
    70021 gttctttttc tatttttacg gaaaggacgt gaagacatga aaaaaataag aagttacacc
    70081 agtatttggt cagtagaaaa agtgatttat gcgattaatg atttacaact ccctttccca
    70141 attaccttta cgcaaatgac atggtttatc gtttctttgt ttgtcgtcat actctttggc
    70201 agtttaccac cactttctct gattgacgga gcactactca aatacttagg gattcccatt
    70261 gttctcactg ggttcatgtg ccaaaagacc tttgacggaa agaaacccta tggatttcta
    70321 aagtctatca ttacctatgc tctacgccct aaagtaacct acgctggcaa acaaatacga
    70381 ttaaaaaaag aaacaatgaa tgaatcgatt acgattgtaa ggagtgaaca actagatggc
    70441 atatccgatt aaatatatgg aagataatct cgtatttaat catgatggcg aagtattcgc
    70501 ttattatgaa ttaattccct ataattacag ttttttaagt tccgatgaaa aaattcaagt
    70561 tcatgataat ttctgtcaat tgattgccca aaatcgtgat ggcaagattc atgctctgca
    70621 actagcaacc gaatcaagta ttcgagccac acaggaacaa tcgaaaaaag aaatcactgg
    70681 acgattaaaa gagatagctt acgaaaaaat agatgaacag accgaagcgt taatttctat
    70741 gattggtgac aatcaagtag actatcgctt ttttattggt tttaaactct acctcaatga
    70801 acaggaagta tccgtaaaaa atgttgggaa agaaattcaa aaagcatttg cggaattctt
    70861 tcatggtgtg aatcacaaat taatgggcga ttttgtttct atgcctatgg cggaaatcga
    70921 acgcttttct aagatggaac agttgttaga aagtaaatta tccagacgct ttcagattcg
    70981 taaattggag aaagatgatt ttggttatat tattgaacat ctttacgggc aaacaggtgt
    71041 cccttttgat gactacgact accatttacc gaaacgatac gaagataaaa aagtgttggt
    71101 aaagaaatac gatattctca aacccactcg ctgtttaatc gaagaaaatc aacgctattt
    71161 acggattgaa caggaagata ccactactta tgtggcgtat tttacaatta atagtattgt
    71221 tggtgaattg gatttcccta atagtgaaat tttttattac cagcaacagc agtttacttt
    71281 ccccgttgat accagtatga atgttgaaat tgtcgccaat aaaaaagcct tatctaccgt
    71341 tcgcaataaa aagaaagaac tgaaagattt agatagccac gcatgggaaa gcgacaacga
    71401 aaccagtact aatgtggtgg acgctttaga atctgtcgat gaattagaaa gtaatttaga
    71461 ccaaaccaaa gaatctatgt acaaactaag ctatgtggta cgggtatcag caaagaattt
    71521 ggacgagctg aaacaacgtt gtgatgaagt aaaagatttt tatgatgatc tgtctatcaa
    71581 attagtacga ccttttggcg atatgctagg cttgcataat gaatttattc cctcaagcaa
    71641 gcgatatatc aatgactata ttcaatatgt cacgtcggat tttttggctg gtcttggttt
    71701 cggtgctaca caaatgattg gtgaaaattc tggtatttac gtcggttaca atctcgatac
    71761 aggcagaaat atttatctcc aacctagcct tgcaagtcaa ggaattaaag gctctgtaac
    71821 aaatgcatta gcgtccgctt ttattggttc attaggtggc ggaaaatcat tctctaacaa
    71881 tatgctggtc tattattcag tactctttgg cggacaggca accattgttg acccaaaagc
    71941 tgaacgtggt gaatggaaag aaaccttacc tgatattgcc catgaaatca atattgttaa
    72001 tctcacgagt gagaacgaca ataaagggtt acttgaccct tatgtgattt taaaactccc
    72061 gaaagattca gaaagccttg ccattgatat tctcacgttc ttaacaggta tttccagccg
    72121 agatagcgag aagtttcctg tcctgcgtaa agctattcgg agtgtaactc aaagcaaaca
    72181 acgagggttg ttattggtga ttgatgaatt gcgaaaagaa gatacgccca tcagcaatag
    72241 tattgctgac catatcgaaa gctttgtcga ttatgatttt gcccatctgt tattcagtga
    72301 tggcagtgtc acccaatcca ttagcttgga aaaacaactc aatattattc aagtggcaga
    72361 tttggtctta cccgattcca atagctcttt tgaagaatac actaccatgg aattattaag
    72421 tgtggcaatg ctgattgtca ttagtacctt tgctttagac tttatccact ctgaccgttc
    72481 catttttaaa attgttgacc ttgatgaggc ttggagtttt ttacaagtgg cacaaggaaa
    72541 agctctatct atgcgattgg ttcgagcagg acgtgccatg aatgcagggg tctatttcgt
    72601 tactcaaaac gcggacgatt tactagatga aaagatgaag aataatattg gcttgaaatt
    72661 tgcctttcgt tccactgacc tagtggaaat caaaaagacc ttagaatttt ttggtgtgga
    72721 caaggaagat gaaaacaatc agaaacgctt acgtgaatta gaaaatggac aatgtttagt
    72781 ttcagacatc tatggtcgtg taggggttat gcagtttcac ccgatttttg aagagttgct
    72841 tcatgccttt gataccagac cgcctgtgcg aaatgaggtg gaagaatgac acaaaaacaa
    72901 aagaaatttc ttcactatag ttggataacg ctcctttgtg tgggcgttat tttactttta
    72961 ttaggcacgc tgggcaatgc agtacaagcg acaggcttag ttgatgaaac cattgataca
    73021 agcaatgaat actccaagta tggtttgaat caatatcagc ttgattatta tgtggacaat
    73081 agctggggct ggcttccatg gaattggagt gatggcatag gacaatcggt gatgtatgga
    73141 ttgtatgcca ttactaattt tatttggaca atttctcttt atctatcgaa cgccacaggt
    73201 tatttggtga aagaagccta tgccttagat ttcattagtc aaacatccca agcaattggc
    73261 gaaaacatgc agacgattgc aggcattaca ccgaatggct tttccagttc agggttttat
    73321 gtcggtttcc tccttctttt tattctcatt gttggaatct atgttgccta tacaggattg
    73381 gttaagcgag aaacgacgaa agtgatacga gctgttttaa actttgtcgt ggtgtttatt
    73441 ctatcggctt cctttattgc gtatgcaccc gattatattg cgaaaatcaa tgatttttcc
    73501 aaagatgtca gtaccgccag tctgaatatt gggacaaaaa ttgttcttcc taacacggat
    73561 agtcaaggga aagacagtgt ggacatgata cgtgacagct tattctctgt tcaagtaaag
    73621 caaccatggc tattgcttca atatggctcc actgatgtag aagcgttagg ggaagaacgt
    73681 gtggaaagtt tattgtctac cagtccagat acaaacaatg gtgaagatag agaaaatgta
    73741 gtgattgaag aaattgaaga tcatgacaat acctatttaa ccctaccgaa gacgatttcc
    73801 agattaggaa cagtcttctt tttgtttgta ttcaatattg gtatctcgat ttttgttttc
    73861 cttctaacag gaatcatgat tttttcgcaa gtgctattta ttattttcgc tatgtttttg
    73921 ccaatcagtt tcctattaag tatgttgccg agttttgatg gcatgggcag gcatgccatt
    73981 accaagttat ttaatgtgat tatgacaagg gctggtatta ccttgattat taccgttgcc
    74041 tttagtattt ccactatgct ttattcgctg tcagcaagtt ctcccttttt catgattatg
    74101 tttttacaaa ttgtgacctt tgcagggatt tattttaaac tgggcgattt aatgagccta
    74161 ttcactttac aaagcaacga ctctcaaaac atgggcagac aagtgtttcg cagacctcgt
    74221 caaatgatga atcgacaaac cagaagattt caacgcagta tgagtaagat ttttcgtgga
    74281 aaagcagggt caacgaagca aaagacaatg acaacaaagc agaatcaaac caataaagct
    74341 aaccatactc gtcaaaatga acggactaca ccaaagaaag aaacagcact ttccaatgtg
    74401 aaaaagcaac aaggcggtat cgggcaacga ttaggtgaaa agacagccca tgtattggac
    74461 acgaaaaatc gtctagtcaa taaaagaaag caggcaaaac aacagataca ggcgacacca
    74521 acccatgtca aatatgccct tcatcaagga aaagagaatg tcactcataa tgtaacagac
    74581 tttaaacaat ctatggcaga taccaaagct caacgcaaac aacagcgtat gaaccagcag
    74641 gagcaaaaac gaaagaacat tgctcaaaag cgtttggagc tggataaagc aaaagaaaaa
    74701 agacgaaaag aaaacccatc atctcctgtt cagaataacc agcagcatgt tcgcaagcgt
    74761 cagcaaaccg tcacgcctgt tttgtcacaa aacactaaac gtgaaaatca tcagcgacca
    74821 ttgaaaaaag agcaaaaaca aaagacacca ccgaagcaat tcaatcagag gaagctaaat
    74881 aaaagaacgg ataagcgagg acaacaaaca tgaagctaaa aataacagtg atttgtagtg
    74941 tggtcttctc tctcttcttt tttctcttat tattcctagt cattttcttt gcagatgata
    75001 cggacagtgg cgaaaacaac aaggattctt ctattccaca aggcggtgtg accgtttcac
    75061 cagaagtgtt ggcacaccgt ccgttgattg aaaaatatgg taaggaatat gggattgaag
    75121 actatgtttc ttatatctta gccattatgc aagtggaatc gggcggtaca gcagaagatg
    75181 ttatgcaaag ttccgaatct ttgggtttac cgcccaacag tttgagtacc gaagagtcca
    75241 tcaaacaagg ggttaaatat ttcagtgaat tattaaccag tgcagaacaa caaggagtgg
    75301 atatagattc tgttatccaa tcttataatt atggcggtgg ctttttaaat tatgtgagga
    75361 gtcatgggaa aaaatatacc tatgaattag ccgaacagtt ttctaaagag aagtcgggtg
    75421 gtcaaaaagc agactatccc aatcctatag ccatacctgt gaatggtggt tggcgatata
    75481 actatggaaa tcagttttat gttcagttgg tttcacaata cctaaccgac acttccccaa
    75541 cagaatttga tggtgaaacc gtgcaagtca ttatggacga agccttgaaa tacgaagggt
    75601 ttccctatgt ctttggaggg gcgtcgccta ccacctcttt tgattgtagt ggcttaatac
    75661 aatgggtgta tgacaaagct ggcatttctc tccctcgtgt cgcccaagat cagtatgacg
    75721 ctacgcaaga aatctctatg gaagaagccc aagcaggcga ccttatcttc tttcattcaa
    75781 cctataatgc aggcacatat gtgactcatg tggcgatata tttagaggga aatcgctttt
    75841 atcatgcagg cgacccaatc ggttatggcg acttaagcag tcgttattgg caagaccatc
    75901 tgattggggc tagacgtgtt attcataact aagaaaggaa tgaatcaaat gattataaaa
    75961 atcgagcgaa aagaaaagaa ggagaaacca aagaaatcta aaaaaccgag caagcaaaga
    76021 aaagttccga tgattaaagt tggcacgcat aagaaattaa cctttgtttt atgggtttta
    76081 ttgattggta gtgtcggatt tggaatctat aaaaatttta ctgccattga cactcatact
    76141 gtccgtgaaa cagaaatcat taaacagcag attgtcgata ccaaccaagt agaaagtttt
    76201 gtgaaatcct ttgcgaaaga ctacttttcg tggcaacaat cccaagaagc cattgataaa
    76261 cgaaatgaaa aattgaccca ttatttgacg gaagaattgc aggtattaaa tgaagaaatg
    76321 attcgtaagg atattcctac tagttctagt gtgaacgata tacaggtgtg gcaggtttct
    76381 caagtgaatg agaacacctt tgaggtactg ttttctgttg aacaagttat taccgaagac
    76441 aaagacaagg aaactatatc gtctagcttt catgtggttg tccatataga tgaatcagat
    76501 aatatggtta ttatcaaaaa tccgacaatg agtaagaaac ctcaaaaatc ggactaccaa
    76561 cccaaacagc tagaaagtga ccatacagta gatacagaaa cgatggacga aatcactagc
    76621 tttttagaaa cgttcttcca gctctatcct accgccacag aaaaagaatt gacttactat
    76681 gtaagtaatc atgtgttacc tatgattaac aaggaatatg ttttcgagga attggtgaat
    76741 cctatcttta ccagaaaaga taaccaagta atcgtgaatg tcgctgtgaa atatttagat
    76801 caagaaacaa aggcaaccca aatctcgcaa tttgagttga tattagaaaa acaagataat
    76861 tggaagattg taaaataaca aatattggta catgattaca gatactttgt aatcatgtac
    76921 tctttttgat aaaaaattgg agattccttt acaaatatgc tcttacgtgc tattatttaa
    76981 gtgactattt aaaaggagtt aataaatatg cggcaaggta ttcttaaata aactgtcaat
    77041 ttgatagcgg gaacaaataa ttagatgtcc ttttttagga gggcttagtt ttttgtaccc
    77101 agtttaagaa tacctttatc atgtgattct aaagtatcca gagaatatct gtatgctttg
    77161 tatacctatg gttatgcata aaaatcccag tgataaaagt atttatcact gggattttta
    77221 tgcccttttg ggtttttgaa tggaggaaaa tcacatgaaa attattaata ttggagtttt
    77281 agctcatgtt gatgcaggaa aaactacctt aacagaaagc ttattatata acagtggagc
    77341 gattacagaa ttaggaagcg tggacaaagg tacaacgagg acggataata cgcttttaga
    77401 acgtcagaga ggaattacaa ttcagacagg aataacctct tttcagtggg aaaatacgaa
    77461 ggtgaacatc atagacacgc caggacatat ggatttctta gcagaagtat atcgttcatt
    77521 atcagtttta gatggggcaa ttctactgat ttctgcaaaa gatggcgtac aagcacaaac
    77581 tcgtatatta tttcatgcac ttaggaaaat ggggattccc acaatctttt ttatcaataa
    77641 gattgaccaa aatggaattg atttatcaac ggtttatcag gatattaaag agaaactttc
    77701 tgccgaaatt gtaatcaaac agaaggtaga actgtatcct aatatgtgtg tgacgaactt
    77761 taccgaatct gaacaatggg atacggtaat agagggaaac gatgaccttt tagagaaata
    77821 tatgtccggt aaatcattag aagcattgga actcgaacaa gaggaaagca taagatttca
    77881 gaattgttct ctgttccctc tttatcatgg aagtgcaaaa agtaatatag ggattgataa
    77941 ccttatagaa gttattacta ataaatttta ttcatcaaca catcgaggtc cgtctgaact
    78001 ttgcggaaat gttttcaaaa ttgaatatac aaaaaaaaga caacgtcttg catatatacg
    78061 cctttatagt ggagtactac atttacgaga ttcggttaga gtatcagaaa aagaaaaaat
    78121 aaaagttaca gaaatgtata cttcaataaa tggtgaatta tgtaagattg atagagctta
    78181 ttctggagaa attgttattt tgcaaaatga gtttttgaag ttaaatagtg ttcttggaga
    78241 tacaaaacta ttgccacaga gaaaaaagat tgaaaatccg caccctctac tacaaacaac
    78301 tgttgaaccg agtaaacctg aacagagaga aatgttgctt gatgcccttt tggaaatctc
    78361 agatagtgat ccgcttctac gatattacgt ggattctacg acacatgaaa ttatactttc
    78421 tttcttaggg aaagtacaaa tggaagtgat tagtgcactg ttgcaagaaa agtatcatgt
    78481 ggagatagaa ctaaaagagc ctacagtcat ttatatggag agaccgttaa aaaatgcaga
    78541 atataccatt cacatcgaag tgccgccaaa tcctttctgg gcttccattg gtttatctgt
    78601 atcaccgctt ccgttgggaa gtggaatgca gtatgagagc tcggtttctc ttggatactt
    78661 aaatcaatca tttcaaaatg cagttatgga agggatacgc tatggttgcg aacaaggatt
    78721 atatggttgg aatgtgacgg attgtaaaat ctgttttaag tacggtttat actatagccc
    78781 tgttagtact ccagcagatt ttcggatgct tactcctatt gtactggagc aagcctttag
    78841 aaaagctgga acagaattgt tagagccata tcttagtttt aaagtttatg caccacagga
    78901 atatctttca cgggcatata acgatgctcc caaatattgt gcaaatatcg taaatactca
    78961 actgaaaaat aatgaggtca ttattattgg agaaattcct gctcgatgta ttcaagatta
    79021 tcgcaatgat ttaacttttt ttacaaatgg gcttagtgtt tgtttagcag agctaaaagg
    79081 atatcaggtt accactggcg aacctgtttg ccagacccgt cgtctaaata gtcggataga
    79141 taaagtaaga tatatgttca ataaaataac ttagtgcgtt ttatgttgtt atataaatat
    79201 ggtttcttat taaataagat gaaatattct ttaatataga tttgaattaa agtggaaagg
    79261 aggagattgt tattataaac tacaagtgga tattgtgtcc tatttgtgga aataaaacaa
    79321 gactacgaat acgagtggat actatactta aaaatttccc tttatactgc cccaaatgta
    79381 agaacgaaac tttaattaat gttcaaaaaa tgaatataat aacaatcaaa gagccagacg
    79441 ccaagacgca gagccgataa tttgagaaat gaaactctca tcttatcggc tctttttgtt
    79501 tatctgaatt ttactgacta gccttcaata tttcttgctt cattgatacc ttttgctagt
    79561 gcttccatta aggatagttc tttgtctgta aagctatcca tgtatttttc tacctgtaac
    79621 cttcgagtgc ttttaatcaa attatctgta ggtaagaaaa attcatcaat agatacatgg
    79681 agtaatgata caagatcata cagcacttgt gtacttgggt gttgtccttt gttttctata
    79741 tttgttaaat aacgtgggtc aatttcaatc attgttccca cttgttcacg agtgagaccc
    79801 cgtttcattc gagcctcttt aatcgctaaa ccaacggctc taaaatcgta tttatcttct
    79861 tttttacgca tactaaatca cctctataca ttttactgtt cctatataac cataaacagg
    79921 tatagaaaaa catgttatat agtttatgag ttcctataga acactgtgga atttattaat
    79981 gcgatgaatc caatttcaaa tagaaaggtc gctgatttta tttacctata caactttata
    80041 aaatttagtc atactcctag aaagtagata aaattggtga cttaatggag ggaaaagtcg
    80101 ccatgagaaa gataatctgt catctagttc tcttaattaa gttcttatca aaaaaactta
    80161 tccacctgta ctggatagat atgaccatca atgtggtttt gcagattaca tagatagaaa
    80221 aatcaaagca tatgaacaga gaaaacaatc tgtttatgtg cttttttggt cacttaataa
    80281 atatctttta ggatttctct tcatttatgc aacaaatccc cctttcgtgt cggggtttag
    80341 tatgaaggga gataaagaag cacatgccac tccctttcac gacagaaagg gggtgaaaag
    80401 catgaaacca tcttcttttc aagaaaccat agaaaatcag tttgactata tctgcaaaca
    80461 agttattgaa gatgaacgaa aagattactt caaacatcta gacagactat cagcaaaaga
    80521 agtctcgttt tctgatatag ataactacct tgtcaactct ttttctactg ttgatacgta
    80581 cgtcactgat ttccaactat ttaaattatt tggattaaga atcaatgttg aaagtgattt
    80641 attaagtgaa gccctgcgtc atctttcaga gaaaaaacgg aacattattt tacttcatta
    80701 ctttatggat atgagtgatg tggagattgc ggagttacta aatttgaatc gttcgactgt
    80761 ttatcgtcat cgaataagtg gactagccat gattaaagaa ttcatgaagg agtgtaaaga
    80821 atgaaaacag cttatccaag ggttcccttc cccctcattg taaaggcgac agatggcgac
    80881 gtggaagcaa ttaatcagat tgttaaacat tatcgagggt atacctcaaa acgttcatta
    80941 cgtcgcatga cagacgaata tggaaattct catatggtta ttgatgaaac cctacgtggc
    81001 agaatggaaa cgaaactcat ctctaagatt ttatcgttcg aaattaaata gtcccatttt
    81061 ttcgtggaag cgtgtcgaat cgtatccacg cttcccgatt tgggaggttt gttattccat
    81121 caaagcatat tgtgtgttca gtaggttttg ataggctaac aagccaaacg ttctttgaca
    81181 accaaataaa ggcaatcgaa tacgtttcgg taagaaaaga gctgatgaac taacacgcca
    81241 tgacctacaa aattagtgag cgattcatgt tagtaattcg aaagtaatct ttagcaggat
    81301 tgctgccatg actttcttat cgtgataatg atactcccgt atagccatag tccgagcgtt
    81361 agaagcgtca caggcaatgg gtacggctac atgagaacca tgcagaagtg aaattcctgt
    81421 gagctttgct agagctgttc gattgctaag atattcttct cttgtcagtg tattattata
    81481 aaactatttg atataattat aggtgaatat tggagttttc ctagcctata attgggaaag
    81541 gagtaataat gataacggtc acaaaaaagg atttagttga gctaggatat ggaacttctt
    81601 tttcagcaga catcataaaa aaagcaaaag aattgatgat tacaaaaggg catatctact
    81661 atcaatctcg aaagctagat agagtccctc gtgaagctgt tgaagaaatt ctaggaattc
    81721 ggttttcaaa tgaaaacagg tctgagtagt ttttgcacag taaggagtaa aaactatggt
    81781 taaagaccca ataaaaaaag caaagaatgg aacctattat tttcgtgcaa atctaggtta
    81841 tgattctaaa gggaaaaaaa ttcaaaaata tcgtagtgga ttcactacta aaaaagaagc
    81901 aagagaagaa tattcgaaac tgctattgat gaaaccagaa gaattaagtg agaataagga
    81961 taaaatgacg tttaaacatt atatctttga aattttcctt ccatggtata agacacaggt
    82021 aaagctcaga acatatgaaa atcgcttacc aactattaag aagcatttct cttattttga
    82081 taaaatggct gtttccgata ttgagcctat tgatgtgcaa aattggcaac taaaattatc
    82141 aaagaagtgt aagtcttctt atgtaagagc tgttcaagga ctattttcag ttgctatgga
    82201 tcgagcaatt gtccttggga taaccaccac aaatccatct aagattattg gcaatgtgaa
    82261 aaagcaaaag tctaaaattg aattttggac aaaagaagaa tttgaaaaag taatctctct
    82321 aatttacaaa gaagattact atcaacactt tttatttatc tctctgtggt ttttatttat
    82381 gactggaatg cgaattggtg aagctactgc cattcaatgg gaagatattg attttgactc
    82441 aggagtacta accatcaaca aaacactcta ttacaagaat caatcgaatt atagatttgt
    82501 tgaaccaaaa acaaaggcga gcgttcgtca tattgtatta gataaatgca cattaactta
    82561 tttatccgaa tggaaggaag tacaacaaaa tctaattcag acagactttg taatgagcta
    82621 taacggtatt cctacccaaa aacatacact atcatatgct attgaacgct atgctaagct
    82681 ggctggtatc catcgaatca gaatccatgg gttacggcat tctcatgctt ccttgttaat
    82741 cagtatggga gaaaatccac ttatcattaa agatcgtcta ggacacgaag atattgagac
    82801 gactttagga acgtatggac atctttatcc taacagtaat ttcgaggtag ctaacaaatt
    82861 aaatggagcc atttccttta aagaagcaaa acaaaattat gatacttcac caaagaatca
    82921 atttactgta gactacttgc gaaacaaaga aatgaaaaaa gtgcaataaa agtgcagtaa
    82981 aaagataaga agagccagaa acccttggta taagaggatt tctagctctc ctacaactat
    83041 tcccactcca ctgttgctgg tggtttagaa gtgatgtcat acacgatacg gttgacgtgg
    83101 gctacttcgt ttacgatacg tacagagatt ttttgcaaga cttcccatgg gatacgggca
    83161 aagtcagcgg tcattccgtc gattgaagtt acagcacgga taccgactgt gtagtcgtaa
    83221 gtacgtccgt cacccataac accgacagag cggatccctg gaagaacagt gaaatattgc
    83281 cagatatcac ggtcaagtcc agcagctgcg atttcttcac gcaagatagc atcagattcg
    83341 cgtacgattt ctagcttgtc ttcagtgatt tcgccaagaa cacgaatacc aagaccagga
    83401 ccagggaatg gctgacgcca aacgattgaa tcaggcatgc ctaactgagt ccctaattca
    83461 cggacttcgt ctttgaataa tgtgtttaat ggttcgatca attcaaattg catatcttct
    83521 ggcagtccac ctacattatg gtgagatttg atcgtctgtg ctgtttctgt accagattcg
    83581 ataacgtcag tatacaacgt tccttgtgct aggaaagaga cgccttcttc accagcaagt
    83641 tttgttgctt cgtcatcaaa aacatatacg aattcattcc caatgatttt acgtttttgt
    83701 tctgggtcag atacaccttt caacttgtct aagaagcgat ctcttgcatc gactttgatg
    83761 atgttcaagc cgaattttcc gcctagactt tccattactt gttccgcttc gcctttgcgt
    83821 agcagaccgt ggtcaacaaa gatagatgtc aattggtcac cgatcgcttt ttgtaaaaga
    83881 accccaacga cactagaatc aacgccacct gaaagaccaa gcaagacttt tttgtcacca
    83941 acttgttcac ggattttttc tacttgcata tcgataaagt tatccattgt ccagttacct
    84001 tcacagtgac aaacatcaaa ggcaaagtgg cgcagcaatt cgattccgta ttcggaatga
    84061 cgtacttctg catggaattg gataccataa aaattacgtg ttgtgtcttg gatagaagca
    84121 atcggacaat ctttgcttgt tccgactgtt tcaaagcctt caggaacttt agttaccaag
    84181 tcaccatggc tcatccatac tgtttgttgt tttggtgttt ctttaaacaa gacagcttga
    84241 tcgcttgtta cttctaacaa ggctttccca tattcgcggt ttttagcagg ctctacggaa
    84301 ccgccaagtt tgtacgtgat caattgcata ccatagcaaa tccctaatac aggaatacct
    84361 aaattgaaga tctcaggatc gatcccaaat gcattctcat catatacact gtttggtccg
    84421 ccagaaagaa tgattccctt tggattcatc gcttttactt cttctgcagt aatgcggtgg
    84481 ctcaataatt cggaaaagac tccaagatca cgaatacgtc ttgtgatcaa ttggttatac
    84541 tgactaccgt agtctaatac gataatcttt tcaacgttcg tcatatcggc aacgtttgtc
    84601 aaatttatta cccctatccc tttaaatttt atctcaaaat agtcaaacta ttttaaaatg
    84661 ctaatatttt cgcatgaaaa tcgaatcgat gatatgattt tcagttttat ggagaattat
    84721 atcggctctt cctcgtgtag gcaagatata ttcctgtaaa tttttcaaat tcacattttt
    84781 ccatacatct tttgccattt taaaggcttc ttcacgatct ccgatagcaa aacgataata
    84841 ataattctct ggattttgga aagccgtatc cagtaacgca ccaaaacgat ccaaatacca
    84901 tttttcgatc agcacgggat cggcatcgac atagacagaa aaatcaaaaa agtcgctgac
    84961 gtagatttgc tgattcgcag gtaattgaag cgtattgatc ccctcaacga tcaagatatc
    85021 aggctgctgg atcaattcgt acttgtctgg aatgatatca tacacatcat gtgagtaaac
    85081 aggtactttt atctcttcct gaccagattt tacacggttc aagaaatcga tcagcatctc
    85141 catatcataa ctttcaggaa atcctttacg gtccatgatt ccacgctctt ttaatatacg
    85201 atttggataa agaaatccgt cagtcgtgat cagctgaacg tttcttcgtt tgaaggtacg
    85261 agacaaaatc gtctgcagca gtctggctgt tgtacttttt ccaacggcta cacttccggc
    85321 gatcccgata ataaaaggcg gtacttctac gtatttatga agaaataaac ctttactcaa
    85381 gaacaaagat tcaaattctt tcatataaag ataaatcaga tgagcaagag gtacatagat
    85441 atctcgaaca tcctgcatgg aaatgcggtc attcaaactt ttgatattat ctagttcatc
    85501 ttgtgtcaaa ggtgcttgcc cattacgata aaattctcgc cattcttctc ttgccacacg
    85561 gtagtagttc attggatcat tcatattagc ctcctgcgtt ctcccatcaa tggaactatt
    85621 ttaacacaaa ataaacgcaa accccaccac ttaagagaga ttgccgatct ttttgtataa
    85681 tctttataat agaaagaaac ggagtcttat tcttgacttg cgcacggata cataaaagga
    85741 tagactgttg tcatgaaaga aatgagaagg atggaagaca tgacaaatca ttactattct
    85801 gaacgcccag atacggcgca cgattttgaa caatgggctt ttgagttaaa aggcagaacc
    85861 tttcaatttg taacagattc tggtgtattt tcacgtgaaa cagtggatta tggttcacgt
    85921 gtcctgattg atgctttcga ttgggaagag ttacctgatg aaggaaagat cttagatgtg
    85981 ggatgcgggt atggaccgat tgggttagct ttggcatttg cgacacagcg gtttgttgaa
    86041 atggtcgaca ttaatgaacg agcggtaagt ctagcgcaag gaaacgcaaa gcgtaaccaa
    86101 atcgaacatg ttgatatcca tcaatcgaat atctatgaag cagttcatga agaaacctat
    86161 gcagctatcg taagcaatcc gccgatccgt gctggaaaaa aagttgtaca tgaaattttg
    86221 acaggcgcat atcctcggtt gaagaagggc ggtacactga caattgtgat ccagaagaaa
    86281 caaggagcgc cgagtgcgca aaagaaaatg gaagaaacat ttggtaatgc agaaatcgtc
    86341 acaaaagata aaggatatta tatcatcaaa agtgtgaaag aataactagc tgaaaaatag
    86401 tggagcgacg aaagagtgga actgggcgtg catgtacggg tacgtatcag ttcttttttt
    86461 gttgagaagt ttttaaaaac aaagaactat tttttcttca aaaagaaata gtaggaacag
    86521 agtcgttgtt ttttacgata aaataaataa gatacagaac ttgtatagaa ggctgccaag
    86581 tcggtagata aaggaggttt ttatcaaaaa acatactttc cttttttctc tattcttttc
    86641 ttgggggttt tggtacactg atagggaatt tagatagaag ggagccaata ggatgaagct
    86701 gaccatcaga gatatcgcag aaatggcagg cgtatcagta acaactgtct cacagatttt
    86761 gaataacaaa ggaagcagat ttagtgataa gacaagaaaa aaagtgttgt cgatcgtgaa
    86821 tgaacatcat tataagcccg attatttcgc ttcaaatgtg atcaatcgac attcaaagac
    86881 catcggaatg atcgtccctg atgtcactga tttcttcttc tccaaactga tcgaaggtgt
    86941 agagagctat ttgaatcctt tgggctatgt gatcatgtta tgcaattctc gtcatagcca
    87001 agaaaatgag atcaagtatt tacaagagct ttcccaccgc tcagtggacg gaatcttgct
    87061 ggccacacca aatattttac ctgagaaata tgcattagac agcggttttt atcaaaaaat
    87121 gccaatcatt ttaatcgatc gcggattgaa tcgtcgggat aacggacggc ttatcgtaaa
    87181 ggaatatgag ggcgcctatc aagctgtttc gctgtttatt gaaaatggcc atacgaagat
    87241 cggcatgctg aaggaaacca ctggatacta tcaattagaa gaacgtttca acggatatcg
    87301 tcatgcgctg aaagatcatg gcctgccttt taatgggaaa tttgttgaac atggagagtt
    87361 gactgtccaa ggtggatata ctgcatcaaa aaaattactc aaacataaag atatcacggc
    87421 tattttttgc gggaatgatg ccatggcgat cggatgctat caggcgatcg atgaattggg
    87481 caaaaaaatc ccagaagata tctcagtcat aggattcgat ggattaaagc tgtcagaata
    87541 catgattccg caattgacga cagtgcagca gccaagtttt gatattggat tttatgctgc
    87601 acgtttcctg atcgatacga tcgaatttcc tcaaagaaaa gttccgaaca aagtgttcga
    87661 aacaaaatta attattcgtg agagcgtaaa agtattgaca aagggctaac tcggcggtat
    87721 attgcttatg taagcattta caaaggctag ttagtgcttt ttttattttt agtaaaccag
    87781 tttactaaag tggtttacct ttcctaaaaa taatgtataa taccgaatga agacaaggag
    87841 gatcaggcaa tgcgaatggt ggatctgatt gaaaaaaaga gggatggaaa cgagctgtcg
    87901 aaagaggaaa tcgagtacat cgtcacgaac tatacgaatg gaaagattcc agattatcaa
    87961 gtcagtgcat tattgatggc aattttttat caagacatga caaatgaaga aatcacgaac
    88021 ttaacattgg cgattgctaa ttctggtgat gtcatcgatt tgagttctct tgaaggaata
    88081 aaggtagata agcattcgac aggtggcgtt ggtgacacga ccacattgat tttagccccc
    88141 ctagtagcta gtgtcggagt gacagtggct aaaatgtctg gacgcggtct aggttacaca
    88201 ggtggtacac tagacaagct agaagcaatt cccggatttc agatcgagct ttcggatgaa
    88261 gaatttgtac gcattgttaa tgaaagtaaa gtagcggtaa ttggtcaatc aggaaacttg
    88321 gcaccggcgg acaaaaaatt gtatgccttg cgtgacgtca cagcgaccgt tgattctctt
    88381 ccgctgattg ccagttcgat tatgagtaaa aaaatcgcgg caggagcaga tgcaatcgtt
    88441 ttggatgtga ccactggaga cggtgctttc atgaagaaca tcgaagatgc aagacgtctg
    88501 gcaaagacca tgacgagcat tgggaaactg gctaaccgag aaacagtggc ggttatctca
    88561 gatatgtcag aacctcttgg cgaagctatc ggaaatagtc tagaagttgt cgaggcaatc
    88621 gaaacattac aaggaaatgg tccagaagat ctagtagaaa tgtgctacgc cttaggaagc
    88681 caaatggttg ttcttgctgg caaagctaag acaaccgatg aagcaagaac gttgcttcaa
    88741 gaagctctgg aatcaggtaa agcgttagca aaattcaaag aaatgatcca aaatcaaggg
    88801 ggagacccag cgatcgtgga acatccagaa cgaattttga ctgcacgcta cacaatggag
    88861 cttcctgcta aacaaagcgg agttgtgtca aaaatcgtgg caaatgaatt aggaattgct
    88921 gcaatgatgc taggtgctgg gcgtaaaacc aaagaagaag atattgatca cgctgttgga
    88981 ttgaaactgc ataaaaaaat tggtgacact gtgacaaaag gtgagtcact attgacgatc
    89041 tatagtaacg acgaagaaat cacttctgtc attgaattat tatataaaaa tattgaaatt
    89101 ggtgaatcgg caatgaagcc aacgttgatt catgacatca tcacagaata aaggaaaaaa
    89161 gcggacttta ccgttttaaa gaaaagggga aaagaaatgg aactaaaccg aatgatcgac
    89221 catactattt tgaaagcaga cgcatctaaa gaagctgtga tgcaaattat cgaagaagca
    89281 aaaaaatacc atttttattc tgtctgcatc aatccagcat gggttgcgct agcgaaagaa
    89341 caattacaag gtgagccagt agccgtatgt acagtaatcg ggtttcctct aggagcaaac
    89401 acacccgaga caaaagcatt tgaaacaaca gatgccatca ataacggtgc agatgaagtc
    89461 gatatggtca tcaatatcgg tgctttgaaa tcaaaggatg atcaacaagt ccaaaaagat
    89521 atcgaagcag ttgttgaagc agcaaaagat cgtgcgcttg tcaaagttat tattgaaaca
    89581 tcgttattag atagagaaga aatcatccga gcttgcgaaa tagcaaaagc tgcaggcgct
    89641 gattttgtca aaacatcaac tggtttctca acaggcggag caaaggtaga ggatgtccgt
    89701 ttgatgcgtg aaactgtagg accagaaatg ggtgtcaaag cttccggcgg tatccataac
    89761 gaagaagaag caatggcaat gatcgaagct ggtgctacaa gaatcggaac aagcgcagga
    89821 gtagcaatcg tatctggttc aactggtgaa ggctattaat tttttcaaag gagaagctca
    89881 tggcagaact caaacaagaa tggatcaaca cagctattga agcgttagat aaagcctatg
    89941 ttccttattc ccattttccg gtaggcgctt gtctcgtaac ggaatcaggc aagatttatc
    90001 aaggcatcaa cattgagaat gcatcatttg gattaacgaa ttgtgccgag cgcacagctt
    90061 ttttcaaagc agtatctgaa ggagaaaaaa catttacgca tctagtcgta gcggggcaca
    90121 cccccgatcc tatctctcct tgtggtgcat gtcgacaagt aatggcagaa ttctgttccc
    90181 ctgatatgcc ggttacgcta gtaggagaca atggtgtgac gaaggcaacg accgttcgtg
    90241 cactgctgcc ttatgcattt actgaaaaag atctataact catgttcatt cagtcagctg
    90301 actgttgaaa aataaaacaa ttattttagg aggctttaca gaaatgaaaa aagcaaaatt
    90361 atttggttta ggtgctgtcg cactagcagc agggttattt ttaggtgcat gcggcaacaa
    90421 cggctctact gattcatccg gtggcaaaag ctcatcagac acaacaactg cagcattgat
    90481 cacagacaca ggtggtgtag acgaccgttc attcaaccag tcagcttggg aaggactaga
    90541 aaaatggggg aaagatcaag gactttcacg aggaaatgat ggcttccaat atttccaatc
    90601 ttcaaatgaa tcagattaca tcccaaatat tgaccaagca ttgaatgctg gattcaaaac
    90661 gatttttggt attggttata aactaaaacc agcgatccaa gaacaagcaa caaacaatac
    90721 aggtacgaac tttgttatta tcgatgatgt catcgatgga ttagataacg ttgtatctgc
    90781 aactttcaaa gacaacgaag cttcttatct tgcaggtgtt gcagcagctt atacgactga
    90841 aacaaacgta gtcggcttta tcggcggtgt aaaaggtgaa gtaatcgatc gttttgatgc
    90901 tggattcaaa gccggtgttg atgcaggtgc gaaagaatta ggaaaagaaa tcaaagtatt
    90961 gaatcaatat gctggtgact tctctgctcc agataaagga cgttcaattg ctcaaggtat
    91021 gtatgcacaa aacgcagata tcatcttcca tgcttcaggc ggtacaggta acggtgtatt
    91081 ccaagaagca aaatcattga acgaatcagg cgacaaaaaa gtttgggtta tcggtgttga
    91141 ccgcgaccaa tcagacgaag gcgaatacac attaaacggc gaaaagaaaa acttcacatt
    91201 gacatctaca ctgaaagcag ttggaacagt agtagaagat ttggcacaaa aatcagcgga
    91261 cggtaaattc cctggcggcg aacacactgt ttatggattg aaagaagacg gtgttggtct
    91321 aacagaagga caactttctg acgaagcgaa aaaagcagtt gatgaagcaa aagaaaaaat
    91381 catttcaggt gacgtaaaag ttccagaaac tcctgaagaa aactaaaacc atttctatag
    91441 ccttgttaga cacatgtttg acaaggctat ggtttgatta gaacaagaat tgttcattta
    91501 tccaagctgc cttgtgacag tttggataag ggaacaactc cctgaagtaa tgtttgtttc
    91561 aaaagaagaa cgctcactaa gcgtgaatct tagtcaatcg ttgccctaga tagaaatcgt
    91621 taggatgtga aaaaaaggtg gttcaagaaa atattgtcat agaaatgcag aatattacca
    91681 aagaatttgg aacattcaag gcaaatgaca acatcaattt acaagtaaag gcaggagaaa
    91741 ttcatgcgtt gcttggagaa aacggtgctg gcaaatctac attgatgaac gtgctttccg
    91801 gattattaga gccgacatca gggaaaattt tgatgcgtgg gaaagaagta aagatcacaa
    91861 gtccgaccaa agccaaccaa ttagggattg ggatggtcca tcagcacttt atgcttgttg
    91921 atgcctttac tgtaacagaa aacatcgtgt tgggaagcga gcctagtcgc gcagggatgc
    91981 ttgaccataa aaaagcacga aaagagatcc aaaaagtttc tgaacagtat ggattgtcag
    92041 tcaacccaga tgcttacgtt cgtgatattt cagttggaat ggaacaacgg gtagaaattt
    92101 taaaaacact ttaccgagga gcagatgtac tgatttttga tgagccgaca gctgtattga
    92161 cccctcaaga aattgatgaa ttaatcgtga tcatgaagga attagtcaaa gaaggcaagt
    92221 cgatcatttt gattacgcat aagttagatg aaatcaaagc agtagctgac cgctgtacag
    92281 ttatccgccg tggaaaagga atcggtacag tcaacgttaa agacgtaacc tcacaacaat
    92341 tagccgatat gatggttgga agaacggttt cattcaaaac gatgaaaaaa gaagcgaagc
    92401 ctcaagaagt cgttttgtct attgaaaatc tagtggtgaa agaaaatcgt ggattagaag
    92461 ccgtgaaaaa cttgaactta gaggttcgtg ctggcgaagt acttggtatc gctggaatcg
    92521 atggaaacgg gcagtcggag ttgatccaag ctttgactgg tttgcgaaag gcagaaagcg
    92581 gacatatcaa gctaaaaggg gaagacatca ctaataaaaa accccgaaaa atcactgaac
    92641 atggtgtagg acacgtgcca gaagaccgtc ataaatacgg gttagtccta gatatgacat
    92701 tatctgaaaa tatcgcacta caaacctatc atcaaaaacc ttacagtaaa aacggcatgc
    92761 tgaattattc agtaatgaat gaacatgcca gagaattgat cgaagaatat gatgttcgaa
    92821 caacgaatga acttgttccc gcaaaagctt tatcaggcgg aaatcagcaa aaagcaatta
    92881 tcgctcgtga agtcgaccga gatcctgatc tgttgattgt tgcaaatcca actcgtggac
    92941 tggatgtagg tgcgatcgaa tttattcata aacgtctgat cgaacaaagg gacaaataca
    93001 aagcagtgtt actgatcagt ttcgaattag aagaaatttt aaatgtttcg gatcgtattg
    93061 ctgttatcca tgaaggagaa attgtcggta tcgttgatcc gaaagaaaca tctgaaaatg
    93121 aattaggtct attgatggcg ggctatacct tagaagaagc acgaaaagag ttagaaaagg
    93181 gggctggcgc acatgaatga tcgcagcgaa aaattccgta atttattagt gcctgtactt
    93241 tcagttgttt taggattgat cttaggcgcg atattgatgg ctgcttttgg ttttcagccc
    93301 atccaaggtt attcttctat gctagatgca gcccttggtt cgcaaagagg gataggtgaa
    93361 acgttaaggc aagcaacgcc gttgattttt acagcattag gtttttctgt agctaactca
    93421 gctgggtttt tcaatattgg gctttctgga caagcacttt gcgggtggat cgtcagtgtc
    93481 tgggtggcac ttgcgtttcc agatctgcca aaagttgttt tgcttccgtt atgcgtgatc
    93541 ttaggtgcct tagctggtgc gatggcagcg gctgttccag gtttacttcg agcatttttt
    93601 ggaacaagtg aagtgatcgt aacaatcatg atgaactata tcttattata cgtaagcaca
    93661 tttgctttac atgaagtgat gcctgaaagc tatcgctcaa gtttggactc ttccaatatg
    93721 atcagtcaaa atgcctcact gcggttacca tggttaacac aagcttttgg cggctctcgc
    93781 gtaaactcag gattattttt agcaatcatc gcgcttattt tcgtttggct gctgatgaag
    93841 aaaacgactt taggatttga aatccgttct gttggattga atccttttgc ttctgagtat
    93901 gcaggaatga gtagtaaacg tacgatcgtt ttgtcgatgg tcatttctgg cgctttggca
    93961 gggcttggcg gtgtggttga aggattagga acgtatcaaa acttctttgt tcaaacgact
    94021 tcgctatcta ttggatttga cggaatggct gtttccttgc ttggttctgg atcagcaatc
    94081 ggtattcttt tatcagcgat cttgttcagt attttgaaga tcggtggact tggcatgcag
    94141 acaggagcag gtgttccgtt tgagatcgtc aatgtatcga ttgctttgat tatcttcttt
    94201 gtcgggatca acttcctgat tcgtttcgtc atggctaaag tcttccaagg gaaaaaacaa
    94261 gaagagatcg ttgcgacaat agaatcgaaa ccaacgaatc aaaaccatga agggggcgaa
    94321 ctataatgtc gactatcgaa ttaattgcct tgatccttac ttctacactg gtttattcaa
    94381 caccgctaat tctaacgtca ctaggcggaa ctttttctga acgaagcggg atcgtaaacg
    94441 tagggctaga gggaatcatg gtcatgggtg cttttagttc catcgttttc aacttgacga
    94501 tgagtccatc acttggttct atgacaccat ggatcgctat tttagtgggt ggcgtcgtag
    94561 gtatcctatt ttctctgatt cacgcagtag caacagtcag tttgcgtgct gaccatatta
    94621 tcagcgggac agtaattaat ctgatggcac ctgctttagg tgttttcttg atcaaagcat
    94681 ggtatggtaa aggtcaaact gataacatca cgcagaatct ggggtatttt tctttcccag
    94741 gattagcaga tattccggtc attggaccaa ttttctttaa aaatacattc ttacctgctt
    94801 attgtgctat tttgattgct gtcctagctt gggtgatcat cttcaagacg aaattcggct
    94861 tgcgcctccg ttcagttggt gaaaatcctc aagctgccga cacattaggt atcaatgtat
    94921 atgctatgcg ttattcaggc gtactgattt ctggcttgtt aggcggtatg ggcggtgctg
    94981 tttttgctca gtcgatttcc ggtaactttt cagctggtac gatcgttgga caagggttca
    95041 tctccatggc tgctatgatc tttggtaagt ggaatccttt aggggcaatg ggtgcctcat
    95101 tgttctttgg ttttgctcaa agcttgagta tcattggcgc acaattacca gttatttctt
    95161 cgattccgcc agtattgctg caaattgctc catatttgct gacaatcatt gtgctggttg
    95221 ttttcttagg gaaagcttct ggtccaaaag caaacgggaa gaactatatc aaatcaaaat
    95281 aatcttttag cgaataaaaa gggtgggtta cgggaagtgt ttttcgtctc gccctttttg
    95341 ttttaaaggc aataaaaata aaaagaaaga aggaataatc atgtttaaac gcgtacatct
    95401 gatcgtcatg gattcagtag gaattggaga agcaccagat gccgataagt tcggtgatgt
    95461 tggttctgat acattaggac acattgcgaa agaagcagga ttgaacgttc cacatttaga
    95521 gcagcttggt ttaggaacga tccgtcctct tgaaggtgtg gaatcagtga aagatcatca
    95581 aggctatgcg acgaaattag aagaagtttc tgtagggaaa gatacgatga caggccactg
    95641 ggaaatcatg ggattgaata tcaaaactcc atttcgtgtg tttcctaatg gattccctga
    95701 tgatctgatc aaacaaatcg aagaattttc tggccgtaaa gtcgtatgta acaaacctta
    95761 tagcggaaca gctgttattg acgattacgg tgaacaccaa atgaaaacag gcgatttaat
    95821 tgtatatact tctgccgatc ctgtccttca gatcgcggca catgaagaaa tcattccttt
    95881 agaagaatta tatcggattt gccaattcgt tcgtgatata acaaaagatg atccgtatat
    95941 gattggccga atcattgcac gtccgtacgt gggtgaacca ggagacttca cacgaacaag
    96001 caatcgccat gattatgcgt tgaatccatt cggacacaca gtccttgatt ctttgaaaga
    96061 agcaggaaag gacgtgattg ctgttggaaa gatcaacgat attttcaacg gacaaggaat
    96121 cactgaatct gtccgcacga aaagcaatat ggatggcgtt gaccagctgc tgaaagttat
    96181 gaaaaacgat ttttcaggaa tcagctttac caatttagta gattttgatg cattatacgg
    96241 tcatcgtcgg gatgtagtcg gctatgcgca tgcgattgaa gaatttgact tacgaattcc
    96301 agaattgctt gaagcgatgg aagaagacga cttgctaatg attacagccg atcacggaaa
    96361 cgatccgacg tttactggta ccgatcatac gcgagaatat gtaccgttat tggtttacag
    96421 taaaaaaatg aaagaacaag gggcattgcc tcaaggatat tattcagata tttcagcaac
    96481 gattgctgag aactttagtg tttcttcgac tgaaaatggc gaaagcttct tgaaattatt
    96541 aaaataatct ttttaaatag gagaaagcaa atgaccaagt taagcgagat gttacaagaa
    96601 acgacccagt ttatccttga taaaggagta aaagaaattg attttggttt gattctaggt
    96661 tcaggattag gtgaattagc agatgaaatc gaagatgctg taatgatttc ttatgatgag
    96721 atcccgttct ttcctgtttc gacagtagtt gggcatgcag gaaagctagt ttatgggtct
    96781 ctggcaggca agaaagtgtt agccatgcaa gggagattcc actactatga aggtcattcc
    96841 atgcaaacag tgacctatcc agtacgtgtg atggccggac taggggccca ttcagtcatt
    96901 gtgactaatg catgtggtgg tgtcaacgaa tcatttgtac caggagattt gatgctgatt
    96961 accgatcata tcaattttac tggtgaaaat cctttgatcg gtccgaatga agatgcaatg
    97021 ggccctagat ttccagatat gagtcaagct tatacgcctg actatcaagc aacagcaaaa
    97081 gcagcagcag aaaaactagg tttggatctt aaagaaggcg tatatatggg ctattctgga
    97141 ccaacttatg aaacgcctgc ggagatccga atgtctcgga caataggagc cgatgcagta
    97201 gggatgtcga ctgttccaga agtcatcgta gcagctcaca gcggattaaa agtgttagga
    97261 atctcttgta ttaccaactt agcagcaggt atgcaagcga atctgagcca tgaagaagtt
    97321 gtagaaacaa ctcagagagt caaacaatct tttaaagcat tggttaaaga aacattgaca
    97381 ttattgtaat aggaggaaca ataaaatgag tgtgcatatt gaagcgaaag aaggcgagat
    97441 cgccgataag attttacttc cgggagatcc tttgcgagct aaatatattg cggagacttt
    97501 tttggaagat ccagtttgtt acaatcaggt acgcggtatg ttaggcttta ccggcaaata
    97561 taaaggagaa cgtatttctg ttcaaggaac aggaatggga atgccatcag ccaccatcta
    97621 tgcccatgaa ttgatccagt cgtatggtgt aaagaaattg attcgagtag gtacatgcgg
    97681 tgcattgtca aaagacgtcc atgttcgtga tttagtacta gcacaaggtg cagcgaccag
    97741 ttcttcgatg atcgaaaaaa atttccaagc ctttcatttt cctccaatca gtgatttcaa
    97801 tctattactg aaagcatatg agatagctaa agaaaagggc tatacggttc atgtaggaaa
    97861 tgttctttcg gaagattctt tctacaaaga tgatttgaca gagacgttcc aattagctga
    97921 acttggcgtt ttaggagtgg aaatggaagc agcggctctt tattacttag gcgcgaaata
    97981 ccatgtgcag acattaagtt tgatgaccgt tagcgaccat ttgatcaccg gtgaagaaac
    98041 aacagctgca gaacgtcaat ctacgttcaa tgaaatgatc gaagtaggat tggaaacagc
    98101 gatagcagaa taagaaggaa atgaaaaagc tgccctgcat taagtaataa gaacatccaa
    98161 gcaaaaatag ctcctcatgt ttttgacttg gctggactta ttattgcaaa tgtaagcttt
    98221 tgaacaccgt ttaccaagag gttgtgaatc tgccgtttaa ctctgagtca caaggaacaa
    98281 tttcaaaaaa cagcttttca tgtttgatga atattgtgac ttgtgaccga gaagttggca
    98341 ggagaaaacc gtttatacga aaaaagggac tgtgacaaat cgtgtcacag tccctttttt
    98401 atagtgtttt ttataggtag tattttttag caactgttaa gtcatcattt aattcataaa
    98461 caagtggttg acctgttgga atttcaagat ccatgatgtc ttcgtcagag ataccttcga
    98521 tatgtttagc tagggcgcgt aatgagttac catgtgcagc tactaaaaca gttttgttgt
    98581 ctagtaatgc tggagcaatt tcatcttgcc agaatggcaa agcgcgttct aatgtcactt
    98641 tcaagttttc tccaccagga atatcgcgtt tgtctaacat tgcgtaacga cggtcatttg
    98701 ctgcagaacc ttcgtcagtt tcttccatta atggaggaag agtatcgtaa gaacgacgcc
    98761 agatgtgcac ttgttcgtcg ccgtattttt cagctgtttc ttttttgttc aaaccttgta
    98821 atttaccata gtgacgttcg tttaagcgcc atgatttgat ttgtggtacc caaagttgat
    98881 ctgaatattc taagatcaag ttacatgttt tgattgcacg agttaaaaca gaagtgtaag
    98941 caacatcaaa ttcgattcca gcttctttga ttttgcgtcc gccttctttt gcttcttcga
    99001 ttccttctgg tgctagattt acatcagccc aaccagtaaa ttggttcaat gcattccatt
    99061 cactaagacc gtgacgagaa aaaactaatt ttggcatgtt tagctctcct tttaagatag
    99121 gtttatattt ctgaaatttt cagttctgtt ttattgtaca attttttgga agagatttcc
    99181 atcgaaaaat tagataagat tctatgagaa aacaagtaga gaatataaaa aaacgaacag
    99241 tgcccacgca actgttcgtt tttaggtatt agatgcataa ttgctcgatt tctttttcag
    99301 gtaaattgat atatttataa catgttccaa ctgaaacacc gcattttgaa gaaataaatt
    99361 ggatcgtttc ttttttttca taatagagac gtcggatttt tttgatcgtt tttgcatcga
    99421 tttttggtct tccgccgatt tttccttttt tacgagcttc atctaatcca actaatgtac
    99481 gttctttgat caatgcgcac tccatgtttg ctaggttttc cattaattgg aaatagattt
    99541 ttcccatttc gcgcgtatcg attccttcat caagactaat caagtgcagc ccgcgatctt
    99601 tgaataattg cgtgagttct gttaattgcc gcgtagattt gcctaatcga tgaagttggc
    99661 aaatgactag tgcatcgcct tgttgcatgt cagcgatcac tgactccaaa tgaacagcag
    99721 tagaatcatt ttgttccact tcatatgtct catggaaaat ttcttgacaa ccaaagtcag
    99781 ataattgatc aacctgagtt gttaaatcaa cgtcatttat ggttgtgcgt gcataaccaa
    99841 taattttcat ggtgattcct ttctagcagt gattttctaa ctggatataa cagtaaaaat
    99901 gtagcataaa gtacgtcaaa aagatagttt tttcgcaaat tttccgctgt ctttttttat
    99961 tggatgatca agcagttttt ctttatttac gacggattgc gtcaagaatc tcaacgcctt
   100021 tttctgagcc gacaactact ttagaaacca tgtttaggaa aagcccatgt tctactaccc
   100081 caacaagttc atctaaatag gtagctaagc tttctggctg ttcgatgact tctagatgca
   100141 gatcaatgat gtaatgacca ccatctgtgg ttaagacttc tccgttttcg tctgtacgca
   100201 agacgggttg gaatcttttt tcttcaaaaa tatgaagtag ctgttgggag ccataaggga
   100261 tcacttcaac tgggagtggg aacttcccaa gtttatcgac taatttagaa gaatcaacga
   100321 tccaaatcgt ttcttttgag tacgtagcga ctattttctc gaaaagcaaa gcagcgccgc
   100381 cgcctttgat cccttgaaaa tcagcactga tttcatcagc accgtctatt gtcaaatcga
   100441 ctacggggac ttcatcaata ctctttaacg gtattcctaa tttttccgct tgttcttttg
   100501 tcgcatttga agtagtaact cctgtgatac gtaaaccttc ttcacgcata cggcgaccaa
   100561 tctcttctac catataatag gcggttgaac cggtcccgag acctacgatc atcccgtcct
   100621 ttacgaattt cgcggcttca atgccagcta attgttttaa attcatcttt gcgtccacct
   100681 ttttttagtt tgagcatcgt gctttcctca ctattttagc gtgatttacg gtaaaaagat
   100741 accattcttt tttattccaa taaagctttt tcaaaaaaaa ttgcatctct tgttgacatg
   100801 ttttttcatt cgtgatattc taacaaaggt gctttatcta caggtttctg tgaagaaacg
   100861 tgctgactgt ttatcaaagc atatttgata aggatgcaga cattgcattt attttttatc
   100921 acaaaaaaag aaccacctgg atgtgtggaa ctagacgcaa atcgtgggaa ggaggaaaca
   100981 aggaatgcct acaattaacc aattagtacg taaacctcgt aaatcaaagg tggaaaaatc
   101041 taattcacct gctttgaaca aaggatataa cagctttaag aaaactcaaa ctaacgtaaa
   101101 ctcacctcaa aaacgtgggg tagcaactcg tgtgggtaca atgacaccta aaaaaccgaa
   101161 ctcagcttta cgtaaatatg cacgtgttcg tttgtcaaac ttaattgaag ttactgctta
   101221 tatcccaggg attggtcata acttacaaga acacagtgtt gtattattac gcggtggtcg
   101281 tgtaaaagac ttaccagggg tacgttacca tatcgttcgc ggtgctttag atactgctgg
   101341 tgttaacgac cgtaaacaaa gccgttctaa atacggaact aaaaaaccta aagcttaatt
   101401 ttaattatta aacaaatgaa acttgcttct actatataga agtaattact atgaacaata
   101461 tttcggaagg aggagttacg gatgccacgt aaaggtcctg ttgcaaaacg tgatgtttta
   101521 ccagatccta tttataactc aaaattagta actcgcttga tcaaccgtgt aatggttgac
   101581 ggaaaacgcg ggattgcagc taacattatc tataatgcct ttgacttgat caaagaatct
   101641 acaggtaacg atccattaga agtgtttgaa caagcaatga aaaacgttca acctgttctt
   101701 gaagttaaag cacgtcgtgt tgggggttca aactaccaag taccagttga agttcgccct
   101761 gaacgccgcg ttactctagg tcttcgttgg gtagtaaact acgctcgctt gcgcggtgaa
   101821 cacacaatgg aagaacgctt agcaaaagaa atcatggatg ctgcaaacaa cacaggtgct
   101881 tctgttaaaa aacgtgaaga cactcataaa atggctgatg ccaaccgtgc gtttgctcac
   101941 tatcgctggt aagattctct ctgtttggtc ggcttttata agtcgacctc agatagtgtc
   102001 cttattttta gcaactagat agtaaagaga ggagaaacaa ggagaatgac cagagaattt
   102061 tctttacaaa acactcgtaa tatcggtatc atggcccaca tcgatgctgg taaaacgact
   102121 gctactgaac gtatcttgta ctatactggt aaaatccata aaattggtga aactcatgaa
   102181 ggagcttcac aaatggactg gatggaacaa gaacaagaac gtggtattac gatcacttct
   102241 gctgctacta cagcacaatg gaagggtcac cgaatcaaca tcatcgacac accaggacac
   102301 gtagacttca cagttgaagt tgaacgttca ttgcgtgtac ttgatggtgc tgtaactgtt
   102361 cttgatgcac aatcaggtgt tgaacctcaa actgaaacag tttggcgtca agcaacaact
   102421 tatggtgtac ctcgtatcgt atttgcaaac aaaatggaca agatcggtgc tgacttctta
   102481 tattcagtat caactttaca tgaccgtttg caagcaaacg ctcacccaat ccaattacca
   102541 attggtgcgg aagacgactt cacaggaatt atcgaccttg taacaatgaa ggctgaaatg
   102601 tatacaaacg atcttggaac agagatcgaa gaaacagaaa ttcctgaaga ataccgcgaa
   102661 ttagctgaag aatggcgcga aaaattggtt gaagctgtag ctgaaactga tgaagaactt
   102721 actttgaaat acttagaagg tgaagaaatc actgaagctg agttaaaaga aggtatccgc
   102781 cgcgcaacag ttaacgtaga attctaccca gtactatgtg gttcagcatt taagaacaaa
   102841 ggggttcaat tactattgga cgctgttctt gattacttgc catcaccgtt agatatccca
   102901 gctatcaaag ggattgaccc taaaactgat gaagaagtag aacgtcctgc agacgacagc
   102961 gctcctttct cagctttagc atttaaagtt atgactgacc cattcgtagg tcgtttaact
   103021 ttcttccgtg tgtactctgg tgttttacaa tcaggttcat acgtacaaaa cgcaacaaaa
   103081 ggcaaacgtg aacgtgttgg tcgtatccta cagatgcatg ccaactctcg ttcagaaatc
   103141 tctgaagttt acgctggaga tatcgctgct gctgttggtt tgaaagacac aactactggg
   103201 gacacactat gtgatgaaaa gagtctagtt attcttgaat ccatggaatt cccagaacca
   103261 gttatccaag tcgctattga acctaaatca aaagctgacc aagataaaat gggtgtggct
   103321 ttacaaaaac tatctgaaga agatcctact ttccgtgctg aaacaaacgt ggaaacaggc
   103381 gaaacaatca tcgctggtat gggtgaactt cacttagata tcatcgttga ccgtatgcgt
   103441 cgtgaattca aagttgaagc taacgtaggt gcgcctcaag tatcttaccg tgaaactttc
   103501 cgtgctggca ctcaagccga aggtaagttt gtacgtcagt ctggtggtaa aggtcaatac
   103561 ggtcacgtat ggattgaatt tacaccaaat gaagaaggtg ctggtttcga atttgaaaat
   103621 gcgatcgtcg gtggggttgt tcctcgtgaa tacattccag ctgttgaaac tggtttgaaa
   103681 gatgctatgg aaaatggtgt cttagctggc tatccattag tagatatcaa agctaaactt
   103741 tacgatggtt cataccatga tgtcgattca aatgaaactg ccttccgtgt tgctgcttct
   103801 atggcattac gtgcagcagc taagaaagct aatccagtaa tccttgaacc aatcatggct
   103861 gtagaagttg ttatccctga agattattta ggtgatgtta tgggtcacgt aactgctcgt
   103921 cgtggacgtg ttgaaggtat ggaagctcgc gctggcggcc aacaagttgt tcgtgcgatg
   103981 gttccacttg ctgaaatgtt tggttatgct acaactcttc gttctgctac tcaaggtcgt
   104041 ggtacattta caatgacatt tgaccactac gaagatgtac caaaatcagt acaagaagaa
   104101 atcattaaga aaaacggcgg aaaagctgaa taatttctta aaaccggata gtcctgcaaa
   104161 gagattatcc aaagagacta tatttttaat atagtttcgt gtaaaataat tatcgatgat
   104221 atgggcatgt ggtgtacctt gtgtacatca tatacctatc agacaaataa aaaatatatt
   104281 gtatttttag gaggacattt taaaatggca aaagaaaaat ttgaccgttc taaaccacac
   104341 gttaacattg gtactatcgg acacgttgac catggtaaaa ctacattaac agctgcaatc
   104401 acaactgtac tatctaagaa aaacggcggc caagctatgg cttacgatca aatcgatggt
   104461 gctccagaag aacgcgaacg cggaatcaca atctcaacag ctcacgttga gtatgaaaca
   104521 gatacacgcc actacgctca cgttgactgc ccaggacacg cggattacgt taaaaacatg
   104581 atcactggtg ctgctcaaat ggacggagct atcttggtag tttctgctgc tgacggccca
   104641 atgcctcaaa ctcgtgaaca catcctattg tctcgtcaag ttggtgttcc ttacatcgtt
   104701 gtattcttga acaaagtaga catggttgat gacgaagaat tactagaatt agttgaaatg
   104761 gaagttcgtg acctattaac agaatacgaa ttccctggtg acgatgttcc tgtagttgct
   104821 ggatcagctt tgaaagctct agaaggcgac gcttcatacg aagaaaaaat tcttgaatta
   104881 atggctgcag ttgacgaata catcccaact ccagaacgtg acaacgacaa accattcatg
   104941 atgccagttg aagacgtgtt ctcaattact ggacgtggta ctgttgctac aggtcgtgtt
   105001 gaacgtggac aagttcgcgt tggtgacgaa gttgaagttg ttggtattgc tgaagaaact
   105061 tcaaaaacaa cagttactgg tgttgaaatg ttccgtaaat tgttagacta cgctgaagct
   105121 ggagacaaca ttggtgcttt actacgtggt gttgcacgtg aagacatcca acgtggacaa
   105181 gttttagcta aaccaggtac aatcacacct catacaaaat tctctgcaga agtatacgtg
   105241 ttgacaaaag aagaaggtgg acgtcatact ccattcttca ctaactaccg tccacaattc
   105301 tacttccgta caactgacgt aacaggtgtt gttgaattac cagaaggaac tgaaatggtt
   105361 atgcctggcg acaacgtaac aatggaagtt gaattaatcc acccaatcgc tatcgaaaac
   105421 ggtactaaat tctcaatccg tgaaggcgga cgtacagttg gtgccggtgt cgttacagaa
   105481 atcaaagctt aattcactta agttttaaag taaagcaaca tttattcgga cgtaatcgct
   105541 cggaacgaag gtcttaggat ctttgttccg agctttttta tttattgcag gatcaggaaa
   105601 aaagacagga gtattataaa tagaagaaac acgaaataaa agagtcagta ttttctaaat
   105661 gaaactttat gaaaacaaaa tgttttttac aagaaaaagc cttgctttgt gagtttatat
   105721 atattataat gacaaaggtg cgtttacttt agtgaattgc acagacgtaa tcagaatgat
   105781 ttcgtcggct aagaaacgag aggttgcgac acgcccggac gctttgccac gaacgagcgt
   105841 gacggaaatt ttcgtggagc tatgtctact tttcaaaata ggcgaaggag ggaacaagat
   105901 ggcaaaacaa aaaattcgta tccgtttaaa agcgtatgaa caccgtattt tagatcaatc
   105961 agcggataaa atcgtggaaa ctgcaaaaag aactggagct agcgtgtctg gtccaattcc
   106021 attaccaact gaacgcagtc tttacacaat catccgtgcg actcataaat acaaagattc
   106081 acgcgaacaa ttcgaaatgc gtacacacaa acgtcttatc gacattgtga acccaacacc
   106141 aaaaactgtt gatgctttga tgaagctaga cttaccatct ggtgtaaaca tcgaaatcaa
   106201 attataaaac taaaacaaaa ataatggagg tgtactcatg accaaaggaa tcttagggaa
   106261 aaaagtggga atgacacaaa tcttcactga atctggtgaa ttaattccag taactgttgt
   106321 agaagctact ccaaacgtag tactacaagt gaaaacaatg gaaacggatg gctacgaagc
   106381 tattcaagtt ggttaccaag atatgcgtga agttttatca aacaaacctg cgaaaggtca
   106441 tgttgcaaaa gcaaacacgg ctcctaagcg cttcattcgt gaattcaaaa atgttgagct
   106501 aggagaatat gaagtaggaa aagaaattac agtagatgtt ttccaagcag gagacattat
   106561 tgatgtaaca ggtactacga aaggtaaagg attccaaggg gttatcaaac gccacggaca
   106621 aagccgcgga ccaatggctc acggttctcg ttaccatcgt cgtcctgggt caatgggtcc
   106681 agttgcacct aaccgtgtat ttaaaaacaa acgtcttgct ggccgtatgg gtggcaaccg
   106741 cgtaactatc caaaacttgg aagttgtacg tgtcgatgca gaaagaaatg ttatcttgat
   106801 caaaggtaat gttcctggag ctaaaaaatc tttaattact atcaaatcag ctgtgaaagc
   106861 taaataattg taggaagaaa ggaggaacta aggaatgccg aatgtagcat tattcaaaca
   106921 agatggaagc caaaacggtg aaatcacact taacgaagaa atcttcggaa ttgaacctaa
   106981 tgaaagtgtt gtttacgatg caatcgtaat gcaacgtgcg tcattaagac aaggaacaca
   107041 cgcggttaaa aaccgtagcg ctgttcgcgg cggcggacgt aaaccatggc gtcaaaaagg
   107101 aacaggtcgt gcacgtcaag gatctatccg ctcaccacaa tggcgtggag gtggcgtagt
   107161 ctttggacca acaccacgtt cttacagcta caaacttcct aaaaaagttc gtcgtttagc
   107221 aatgaaatct gtattgtcag aaaaagttgc tgaaaacaac ttggtagcaa tcgaaggctt
   107281 gaacttcgac gcaccaaaaa caaaagaatt caaacaagtt cttgctaact tatctatcga
   107341 ctctaaagta ttggttgttc tagaaaaagg taacgacttt gctgctttat cagcacgtaa
   107401 cttaccaaac gtttctgtag taacttctga taatgtgagt gtgctagacg ttgtatcaaa
   107461 tacaaaagtg ttagcaacac aaactgctct tactcaaatt gaggaggtgc ttgcataatg
   107521 aacttactag acgtaatcaa acgcccagtg atcactgaaa aatcaatgct tgccatggat
   107581 gacaagaaat acacttttga agtggacact cgcgcaaaca aaactttagt aaaacaagcg
   107641 gtagaagctg cttttgacgt taaagtcaaa aacgtgaaca tcgtgaacgt acgtgcgaaa
   107701 ttcaaacgta tgggcaaata tgcaggatat acaaaaaaac gtcgcaaagc gatcgttaca
   107761 ttgactgaag attcaaaaga aatccaatta ttcgaagctg ctgaataagc actaatagat
   107821 aactcattaa attaggaggg aaaaacgtgg cgattaaaaa gtacaaacct acctcaaatg
   107881 gtcgtcgtaa catgacaggt tctgattttg ctgaaatcac aacatcaaca cctgaaaaat
   107941 cattgttaca accattgaaa aaccatgctg gacgtaacaa caacggccgc atcactgtac
   108001 gtcatcaagg tggcggacac aaacgccaat atcgcgtgat cgacttcaaa cgtaacaaag
   108061 ataacgttgt tgcaactgtt caaacgatcg aatatgatcc aaaccgttca gctaacatcg
   108121 cgttagtaca ctatgaagat ggagtgaaag cttacatctt agcacctaaa ggactagaag
   108181 tgggtatgaa acttgtttca ggtccagaag cagatatcaa agtcggaaat gctcttccat
   108241 tagaaaacat tccagttggt actgttatcc acaacattga aatgaaacct ggtaaaggtg
   108301 gacaattgat ccgttctgct ggtacaagtg ctcaagtact tggtaaagaa ggcaaatacg
   108361 tattgatccg cttgaactct ggtgaagttc gtatgatctt agctgcatgc cgtgctacaa
   108421 tcggttctgt aggtaacgaa caacacgaat taatcaacat cggtaaagct ggacgctctc
   108481 gttggatgcg taaacgccca actgtacgtg gtagcgtaat gaaccctaat gatcacccac
   108541 acggtggtgg tgaaggtaaa gctcctatcg gacgtaaagc accagtttct ccttggggtc
   108601 aaccagctct tggttacaaa actcgtaaca aaaaagctaa atcagacaaa cttattgttc
   108661 gtcgtcgcaa aaataaataa ttactttgac catgtgtcgc acattttgag aggaggttca
   108721 ccatgggtcg tagtttaaag aaaggacctt ttgtcgatga gcatttaatg aaaaaagttg
   108781 aagctcaagc aggggttgaa aagaaaaaag ttatcaaaac ttggtcacgc cgttcaacag
   108841 ttttcccaag ttttgttgga tataccatcg cagtttatga tggacgtaaa catgtaccag
   108901 tttacatcca agaagacatg gtaggacaca aattaggtga atttgcacct acaagaactt
   108961 atcgtggaca tgctgctgac gataagaaaa cgaaacgcta atttgagggg aggataaatc
   109021 caaatggcag aacaaatcac atcagctaaa gcaactgcaa aaacagttcg cacttcacct
   109081 cgaaaagccc gtttagtaat tgaccttatc agaggtaaaa gtgtcgcaga tgcaatttca
   109141 atcttgaaat tcacaccaaa caaatctgct ggaatcattg aaaaagtatt gatgtcagca
   109201 gttgcgaatg cagaaaataa ctttgactta gatgttgaaa acttggtagt aagcgaagct
   109261 tttgttaacg aaggacctac aatgaaacgt ttccgtcctc gtgcaaaagg atcagcttct
   109321 ccaatcaaca aacgtacaag tcatatcacg gtagtcgtat cagaaaaata aggagggata
   109381 atcagtgggt caaaaagtac atccaattgg aatgcgtgta ggcatcatcc gcgactggga
   109441 tgctaaatgg tatgctgaaa aagagtatgc tgagttctta cacgaagatt taagaatccg
   109501 taaatttatt tcaactaaac ttgctgatgc tgctgtatca acagttgaaa tcgaacgcgc
   109561 aacaggtcgc gtaaacattt caattcacac agctaaacca ggtatggtta ttggtaaagg
   109621 cggttctgaa gtcgaaagcc taagaaaaga attaaacaaa ttaactggta aaagaatcca
   109681 tatcaatatc gtggaaatca aaaaaccaga tctagatgca aaattagtag gtgaaggaat
   109741 cgcacgtcaa ttagaaaacc gtgttgcttt ccgtcgcgct caaaaacaag ccatccaacg
   109801 ctcaatgcgt gctggcgctc aagggatcaa aactcaagta tctggtcgtc taaacggagc
   109861 agatatcgct cgttcagaag gatactcaga aggaactgtt cctcttcata ctttacgtgc
   109921 ggacattgat tacgcatggg aagaagcaga tacaacatac ggaaaactag gagttaaagt
   109981 gtggatctat cgtggagaaa ttcttccaac taaaaaaaac actgagaaag gagggaaata
   110041 atcatgttag tacctaaacg tgtaaaacac cgtcgtgaat tccgcggaaa aatgcgcggg
   110101 gaagctaaag gcggaaaaga agtagcattc ggtgaatacg gtttgcaagc tgttgattca
   110161 cattggatca caaaccgcca aatcgaagct gctcgtatcg caatgactcg ttacatgaaa
   110221 cgtggtggga aagtatggat taaaattttc cctcacaaat cttatactgc caaagcaatt
   110281 ggggtacgta tgggttctgg taaaggggca cctgaaggat gggttgcacc agtaaaacgt
   110341 ggtaaaatca tgtttgaaat cgcaggcgtt cctgaagaag tagctcgtga agcgttacgt
   110401 ctagcttctc acaaattacc aatgaaaact aagatcgtaa aacgtgagga aatgggtggt
   110461 gaatcgaatg aaggttaaag aaatcagaga attaaccact gccgaaatgc ttgatcaaga
   110521 aaaacaatta aaagaagaat tgtttaatct tagattccaa ttagcaacag gtcaattaga
   110581 aaacactgca cgtattaaag aagtacgtaa atcgattgca cgcatcaaaa ctgtgttgcg
   110641 tgaacaagct aagtaattat ggaaggaggc cattaagcgt atgactgaag gaagaaatca
   110701 acgcaaagtt tatcaaggtc gcgtggtttc agacaaaatg gataaaacaa ttaccgttgc
   110761 tgtcgaaaca aagaaaaacc accctatcta tggcaaacgc atgaactatt ctaagaaata
   110821 caaagtgcat gatgaaaaca acacagcaaa agttggcgac atcgtgagaa ttatggaaac
   110881 tcgtccatta tcagctacaa aacgtttccg tttgttggaa gtagtcgaag aagcagttat
   110941 tatctaataa cacgagattt tcctatatag attgaatgca aaatctgaaa ggaggataca
   111001 caacgtgatc caagcagaaa gtcgtttaaa agtcgctgat aactcaggcg cacgtgaaat
   111061 tttgacgatc aaagtccttg gtggatctgg tcgtaaaact gctaacatcg gtgatgtgat
   111121 cgttgctacg gttaaacaag caacgccagg tggggttgtc aaaaaaggtg acgtcgttaa
   111181 agccgttatc gttcgaacaa aatcaggagc tcgtcgtaca gacggttcat atattaaatt
   111241 tgatgaaaat gctgcagtga ttattcgtga tgataaaagc cctcgtggaa cacgtatctt
   111301 tgggccagtt gcacgtgaac tacgtgaaaa caacttcatg aagatcgttt cactagcacc
   111361 agaagtttta taatcttgag acacttatca aaggaggtgc gaaacagtta tgtttgttaa
   111421 aaaaggcgat aaagttaaag ttatcactgg aaaagacaaa aacaaagaag gcgttgtact
   111481 agcagcgttc ccgaaaaaag ataaagttat tgtcgaaggt gtaaatgtcg ttaaaaaaca
   111541 ccaaaaacct tctcaagctg ctcctcaagg tggaattgtt gagatggaag cgccaattca
   111601 tgtttctaac gtgatggtgg ttgactctac tggtgtagct ggccgagttg gctacaaaga
   111661 agtagacggc aaaaaagtcc gtgtttctaa aaaaaccggt gaagttttag ataaataaaa
   111721 gtttaaggaa ggagggtctt actgaatgaa ccgcctaaaa gaaaaatatc ttaaagaagt
   111781 aactccatca ttgatggaaa aatttaacta tagctctgtt atgcaaacac ctaaagttga
   111841 aaaaatcgtc atcaacatgg gtgttggtga tgcggtatca aacgctaaaa acttagataa
   111901 agcagttgaa gaattaactt tgatcactgg tcaaaaacca atgattacaa aagctaaaaa
   111961 atcaatcgct ggattccgtt tacgtgaagg aatgccaatt ggtgcaaaag ttacattgcg
   112021 cggagaaaga atgtacgaat tcttagacaa attggtttct gtttcactac cacgtgtacg
   112081 tgacttccat ggtgtaagta aaaaagcctt tgacggtcgt ggaaactata ctttaggtat
   112141 taaagaacaa ttgatcttcc cagaagtaga ttatgattta gtagataaag tacgtggtat
   112201 ggacatcgtt attgtaacaa cagcaaactc tgatgaagaa tctcgtgagt tgttgacaca
   112261 attaggcatg ccattccaaa aataattaaa ggaggcgaac tacgtggcta aaaaatcaat
   112321 gattgctaaa aacaaacgtc ctgcaaaatt ttcaacacaa gcttatactc gttgcgaacg
   112381 ttgcggacgt ccacattcag tttatcgtaa gttccatctt tgccgtattt gcttccgcga
   112441 acttgcctat aaaggtcaaa ttcccggcgt gaagaaagct agctggtaaa aagtaaattc
   112501 gcataagaag gaggtaaaag atcaatggtc atgacagatc caattgcaga ttttctaact
   112561 cgtatccgta acgcaaacat ggttaaacat gagtctttag aagtacctgc atcaaaaatt
   112621 aaacgtgaca tcgctgaaat cttgaaacgt gaaggtttcg ttcgtgatgt tgaatacatc
   112681 gaagatgaca aacaaggcgt gatccgtgtt ttcctaaaat ttggtaaaaa cggcgaacgt
   112741 gttatcacaa acttaaaacg tatctctaaa ccaggtttgc gtgcttatgt caaagctgac
   112801 gaagtaccaa aagtattgaa cggtttaggt atcgcaatca tttcgacttc tgaaggtgtt
   112861 gtcactgata aagaagctcg tgaaaaaaat atcggcggcg aagttatcgc ttacgtatgg
   112921 taatcaagta gaatctacaa ggaggtgtct ttaagtgagc cgtatcggaa ataaagtcgt
   112981 tgttatccct gaaggagtaa cagttactca agacggaaac aacgttacag ttaaaggacc
   113041 aaaaggtgaa ttgactcgta ctttttcagc agatatcaaa atgaatatcg aaggaaacga
   113101 agtaactttc actcgtccaa acgacagtaa agaaatgaaa acaattcatg gaacaactcg
   113161 tgcgaacttc aacaacatgg ttgtaggtgt cagcgaaggt ttccaaaaag cgttagaact
   113221 aatcggggtt gggtaccgtg cacaattaca aggatcaaaa cttgtattga acgttggtta
   113281 ctcacatcca gtagaaatca caccaccagc tggagtaact gttgaagtac cagctaacac
   113341 acaagtaatt gttaaaggtg cgaacaaaga agaagttggc gaattagctg caaacattcg
   113401 tggaactcgt cctccagaac cttataaagg taaaggtatt cgttatgttg gcgaatatgt
   113461 acgccgtaaa gaaggtaaaa ctggtaaata atcgtttaga aaaattgcat agaagccagc
   113521 agcaggaaaa aggcatttgg ctgaagttta ccttcaaaaa aatacatttt tacttgtgcc
   113581 gcagcttcta tttttcgaaa cgtatttact gcttgaaata gtagtacaat aaaaataaag
   113641 aggtgacaat tgtgattaca aaaccagata agaacaaaac acgtcaaaag agacatcgtc
   113701 gtgtacgtaa caatatctct ggtactgctg agcgcccacg cttgaacgtt tttcgttcta
   113761 acaaaaacat ctacgctcaa attattgatg acgtagcggg tgtaacgcta gcaagtgcct
   113821 ctaccttgga taaagaaatt tcaggtggaa caaaaacaga agcagcacaa gctgtcggta
   113881 aactagttgc tgaacgtgca gctgaaaaag gcattaaagt agtagtcttt gaccgtggtg
   113941 gataccttta ccatggccgt gtgcaagctt tagctgaagc tgctcgcgaa aatggactag
   114001 aattttagaa gaaggaggaa taccattcat ggtttatatc gatccaaaac atttggaatt
   114061 agaagaccgc gttgttgcaa ttaaccgtgt aacaaaagtt gttaaaggtg gacgtcgtct
   114121 acgttttgct gctttagttg ttgtcggtga caaaaacgga cacgtagggt ttggtacagg
   114181 taaagctcaa gaagttcctg aagcaatccg taaagcaatt gaagatgcga agaaaaactt
   114241 agttgaagta cctatggttg gttcaacaat cccacacgaa gtaatcggtg cttttagtgg
   114301 tggtagaatc ctaatgaaac ctgctgtaga aggttctggg gttgctgctg gtggaccagt
   114361 tcgtgccgta ttagaattag ctggggtagc agatatcact tctaaatctt taggctcaaa
   114421 tacaccaatc aacgttgttc gcgcaacagt tgaaggtttg aaacaattga aacgtgcaga
   114481 agaagttgca gaacttcgcg gcaaatcagt tgaagaatta atcggataag gaggacaaca
   114541 ataatggctg aattaaaagt tactttaaaa cgcagtatta tcggacgtcc tcaaaaccaa
   114601 cgcgatacag ttaaagcgtt aggtcttaca aagattaaca gttcagtggt taagccttct
   114661 aatgaagcaa ttaaaggcat gatcaatact gtttctcacc tagtggacgt tgaagaaatt
   114721 taatttagaa aaatcataac tagaacatta aggaggtgcc aaacctatga aacttcatga
   114781 attaaaacct gctgaaggtt cacgccaagt acgtaaccgt gttggtcgtg gtacttcatc
   114841 tggtaacgga aaaactgccg gacgcggaca aaaaggacaa aaagctcgtt caggcggcgg
   114901 tgtgcgttta ggatttgaag ggggacaaac accattgttc cgtcgtttac caaaacgagg
   114961 attcacaaac gtgaaccgta aagactatgc agtcattaat cttgatgtat tgaaccgctt
   115021 tgaagacgga gctgaagtaa ctcctgttgc tttagttgaa gctggaatcg tgaaaaacga
   115081 aaaagctgga atcaaagtat tagctaatgg ggaactaaac aagaaattaa ctgtgaaagc
   115141 agcaaaattc tctaaagcag ctcaagaagc aattgaagcg gctggtggat caatcgaggt
   115201 gatctaatgt ttagactatt aaaagatgct tttaaagtaa aagacattag atcgaaaatc
   115261 ctatttactg tatttgtgtt gtttgtattt cgcctaggtg cacatattac tgtaccaggc
   115321 gtaaatgctg cttcattgca aaacctttct tctttgccat ttttcaacat gttgaacttg
   115381 gtaagtggta gtgcgatgca aaacttttcc attttctcaa tgggggtttc accatacatt
   115441 actgcttcta tcgtcattca gcttcttcaa atggacatcg tgcctcgatt tgttgaatgg
   115501 tcgaaacaag gggaagttgg tcgtaaaaaa ctgaatcaag cgactcgata tctgacatta
   115561 gtattggcat ttatccaatc tgtcggtatc actgctggat tcaatcaata cgctcaatta
   115621 ggtttcgtga ataatcctaa cgtagcaact tacgtaacga tcggtttgat tctaacagcc
   115681 ggtacgatgt ttgttacttg gctaggagaa cagatcacag aaaaaggtat cggaaatggc
   115741 gtatcaatga tcatttttgc aggtatcatt tctagattgc ctgaaagtat cagagaaatt
   115801 tatgaagatt actttataaa tattgatcct tcagacatat ggaaatctgc tatttttgtg
   115861 gccattttac tagtagcggt cttgttgatc gtgacattcg taacattttt ccaacaagct
   115921 gaacgcaaga tcccgatcca atatacgaaa cgcgtagctg gcgcgcctac aagcagctat
   115981 ctgccgttga aagtaaatgc agctggagtt attccagtta tctttgctag ttcgtttatt
   116041 gctacgccaa atgctgtttt acaagcattg agcggtagat tcggttctga aaactggtac
   116101 aaagtgatga tggagatctt taactataat acagcacctg gtgctacgat ttatacgatt
   116161 ctgatcgttg ccttcacttt cttctacgcc tttgttcaag taaaccctga gaaattagcg
   116221 gaaaacttgc aaaagcaagg aagttatata ccaagcgtac gccctggtaa ggggactgaa
   116281 gagtatgtct caagattact gatgcgttta agtacagttg gtgcagtctt ccttggttta
   116341 gtggcattgc ttccaatcat tgctcaaatg gtttgggatc ttccacaatc aatcggatta
   116401 ggcggtacaa gcttactgat cgttatcggt gtagctttag aaactgcgaa acagttagaa
   116461 ggcttaatgc tgaaacgtaa atatgttgga ttcattgagt aagaaagcgt gttgaggttt
   116521 cccctcaaca cacgttctca cacatttatt aggagggaaa acaatgaacc tcattttaat
   116581 ggggctgcca ggcgcaggta aaggaacaca agctgaaaaa atcattgatg cttatggtat
   116641 tccgcacatc tcaacaggag atatgttccg cgcagcgatg caaaacgaaa cagctcttgg
   116701 cctggaagca aagtcttata tggataaagg tgcattagtt cctgatgaag taacaaatgg
   116761 aatcgtgaaa gagcgactag ctgaaccaga tacagagaaa ggcttcttat tagatggctt
   116821 tccacgtacg ctagatcaag caaaagctct ggacgcaatg ctaaaagatt tgaataaaaa
   116881 aattgatgct gtcatcgata tccatgttgg tgaagaaatc ttggtcgaac gtctagccgg
   116941 ccgatttatc tgcagcaatt gtggagcaac ttaccataaa attttcaacc ctacaaaagt
   117001 tgaagacaca tgtgatcgtt gcggtgggca tgaattctat caaagagaag atgataaacc
   117061 tgagacggtt aaaaatcgtc tggctatcaa catcaaaaat agtgaaccaa tcttggctta
   117121 ttataaagaa caaggtttgc taaacactat tgatggtgct cgtgaaatcg atgctgtatt
   117181 tgcagatgta caaaaaatca ttgaaaaata gcacgattgc ccgtagccga cttgcattat
   117241 gcagttactc ttgtcaagtt caataaatta tgatagaata tgtcagtccg acttctagag
   117301 aatcctctag atgatccatt ttgagaattt tgaggtggga actgcagttt ccgccatttt
   117361 atcgtgtgaa aatgcgaaac aagtacaagg aggtactgtg cgtggcaaaa gaagatatga
   117421 ttgaagtcga aggtacagtc gtcgaaactt tgccgaatgc aatgtttaaa gttgaactag
   117481 aaaacggaca ccaagttctt gctactgttt caggtaaaat tcgtatgcat tacatccgta
   117541 tcttacctgg tgacaaagta acggttgaat tgtctccata cgatcttaac cgtggccgta
   117601 ttacttatcg ctttaaataa ttgtactccg taaaactaca ggaggtatta tcatgaaagt
   117661 aagaccatca gtaaaaccaa tgtgcgaaca ttgtaaagta attcgtcgta aaggacgcgt
   117721 tatggtgatt tgcccagcaa atccaaaaca taaacaacgt caaggataat tggaggtgct
   117781 ataaatatgg ctcgtattgc aggagtagat attcctcgtg ataaacgtgt agtagtttca
   117841 cttacttata tctatggtat tggtaacact actgctaaaa agatcttagc tgatgctggt
   117901 gtatctgaag atgttcgcgt tcgtgaatta acgaatgaac aaacagatgc tatccgtgca
   117961 gaagtagata aattaaaagt tgaaggggat cttcgtcgtg aagtgaactt gaacatcaaa
   118021 cgtttgatgg aaatcggttc ttaccgtgga atccgtcatc gccgtggatt gcctgttcgt
   118081 ggacaaaaca cgaaaaacaa tgcacgtact cgtaaaggcc cagctcgcgc tatcgctggc
   118141 aagaaaaaat aattcttaag tgaaggaggt taaaacttca tggcagcaaa aaaagtgaat
   118201 cgtaaacgcc gtgtgaagaa gaatatagaa gcaggtattg cacatatcca ttctacattc
   118261 aataacacta tcatcatgat cactgatact cacggaaatg cattagcgtg gtcatcagct
   118321 ggttcattag gtttcaaagg aagcaaaaaa tcaactcctt ttgccgctca aatggcagca
   118381 gaaactgcta caaaagcagc aatggaacac ggattaaaga ctgttgaagt aacagttaaa
   118441 ggacctggtt ctggacgtga agcagcaatt cgttcattac aagctacagg tttagaagtg
   118501 actgcaattc gtgacgtgac tccagttcct cataatggtg cccgccctcc aaaacgccgt
   118561 cgtgtttaat gagtgccgct cattttgagt tttatcagta acgtcattga acaagacact
   118621 tttcgttttg aaaggggtaa agataagaat gattgagttc gaaaaaccaa gaatcgcaaa
   118681 aattgatgaa gaaaaagatt atggcaagtt catcgttgaa cctcttgaaa gagggtatgg
   118741 gactacttta gggaattccc tacgtcgtat tttattatct tctttgccag gtgctgccat
   118801 cactaatatt caaatcgatg gtgtactgca tgaattctct accatcaaag gtgttagaga
   118861 agacgtcact caaatcatct tgaacattaa aggcttagcg ctgaaaatgt atggccaaga
   118921 agaaaaaacc cttgaaatcg atattaccgg acctgctaca gtaactgctg gcgatattat
   118981 cgttgatagt gatgtagaaa ttcttaacaa agatatgtac atctgtagtg tctctgaagg
   119041 agctacgttc catgctcgct taacagtgaa acctggacgt ggttatgttc aagcagatga
   119101 aaataaaaaa gaagatatgc caattggcgt tcttccagtc gattcaatct acacacctgt
   119161 tcgtcgtgtg aactatcaag ttgagaacac acgtgttgga caccgtgaag attttgataa
   119221 attgacgatg gagatttgga cagatggttc aattgaaccg ttggaagcaa tgagtttgtc
   119281 tgcgaaaatc atgactgaac atttggatat ttttgtgaac ttaactgatg aagcaaaaaa
   119341 tgctgaaatc atggtcgaaa aagaagaaac acaaaaagaa aaaatgttgg aaatgacgat
   119401 cgaagagtta gacttgtctg ttcgctctta caattgtttg aaacgtgcag gaatcaatac
   119461 tgtacaagaa cttacaaata aatctgagcc tgaaatgatc aaagtccgta acttaggacg
   119521 taaatcatta gaagaagtta aagcaaaatt gcacgactta ggtttaggtt tacgtaaaga
   119581 agattaaaac cttttacgaa ggagggaaac caacgtgagt tatcgtaaac taggacgcac
   119641 atctagccaa cgtaaagcga tgttgcgtga tttaacaact gatttattaa tcaacgaacg
   119701 tattgtgact actgaagctc gtgcgaaaga agttcgctca actgcagaaa aaatgatcac
   119761 tttaggtaaa cgcggagatt tgcatgcacg tcgtcaagct gcggctttcg tacgtaatga
   119821 agttgccagc gtgcgtgaag aaaatgagga catcgtcatt gaatcagctt tacaaaaact
   119881 gttcaacgat attgcacctc gttacgcaga acgtcaaggc ggatacacac gcattttgaa
   119941 gacagaacca agacgcggtg atggtgcacc aatggttgtc ttagaacttg tctaaaatca
   120001 cactaataac atcactttat agatgattct tttagagtgt tatgatgttg gaagatattt
   120061 ttccgagtct agctcagcgc tgctcctcaa gcgaatatcg cttggggagt aagcactcat
   120121 cataaagtgt ttttttatac cttcaattac ctgtcatgac agatatgttt gaaggcataa
   120181 aaaaacattt taagcgagaa ataattgaaa attttgtctt tttttgatag tgttagtagg
   120241 aactttagga tgaagaagga gtaatcatgg agccaattat tgaattagaa aagataaatt
   120301 ataaatacca gccagatgat cttcgccccg cattgaaaga tgtctccttt acaattgata
   120361 aaggtgagtg gatcgctatt attggacaca atggttcagg aaaatcgaca cttgccaaaa
   120421 cgatcaatgg attgcttctg ccagaatcag ggatcgtgaa agtgggaaat caaatattgg
   120481 atgaagaaaa tatttggacg atccgacaga tggttggaat ggtttttcaa aatccagaca
   120541 atcagtttgt tggttcgaca gtagaagatg acgttgcttt tggtcttgaa aatcaaggga
   120601 ttcccagaga agaaatgcta gtgcgtgtga aagatgcact tgagaaagtt agaatggctg
   120661 agtttgcttc acgcgagcct gctcgtttat caggagggca aaaacaacgt gttgccattg
   120721 ccggcgtggt tgccttacga cctgatatca ttattttaga tgaagcaacc agtatgctag
   120781 atccagaagg tcgtgaagaa gtgatctcta cgatcaagaa gatcaaagaa gaaagtcaat
   120841 tgaccgttat atctatcact catgatattg atgaagcagc taatgccaat cggatactag
   120901 tgatgagaca aggcgaactt gtccgtgaag gtacaccaaa agaaattttt tctgctggtc
   120961 ctgaactgat cgacttaggt ctagatctac catttcctga aaaactgaag agcgcactga
   121021 aagaacgtgg ggttgatgtg cccagtgaat atatgacaga agaaaggatg gtggattggt
   121081 tatggacatc cgttttgaac aagtagactt cacttatcag ccgaatacac catttgaaca
   121141 aagagcctta tttgacatca atatgacgat caaagaaaac agttatactg cattagtagg
   121201 gcataccgga agcgggaaat caaccttact tcagcatttg aatgcgcttg ttaagccaac
   121261 aagcggtaca gtccatattg gagaacgaga tattcagccg gatacggata ataagaattt
   121321 aaagcccatc cgaaaaaaag ttggcatcgt ctttcagttt ccagaagcac agctattcga
   121381 agaaacggta gcaaaagaca ttgctttcgg tcctaaaaac tttggtgtca gcgaagaaga
   121441 agcactagtc ctagcaaaag aaacattaga acaagttggg ctggatgaaa gctatttgga
   121501 acgttcgcca tttgaacttt caggagggca aatgcgtaga gtagcaatcg ctggtgtgct
   121561 tgccatgagg ccggaagtac ttgtattgga tgaaccaacg gcaggacttg atccccaggg
   121621 cagaaaagaa atgatggaga tgttttggcg tcttcataag gaacagcaga tcactattgt
   121681 attagttacg catttaatgg atgatgtagc caattttgca gattatgtct atgtgttgga
   121741 aaagggacga atcgttaata gcggggagcc gcaagaggtc tttcaaaaca ttgaatggct
   121801 aaaagaaaaa caactaggcg tacctactgc caccgagttt gcagaagaat taatggctaa
   121861 agggatgaac tttgctacct tgcctttgac agctgaagaa ttagcagacg ctatcgtcca
   121921 ttatgctgga ggaaatgccc atgatgaata aattgatatt tggtcgttat atgcctggag
   121981 attccttgat ccatcgattg gatccccgag ctaaattatt agccagtttt tattttatcg
   122041 gaatcatttt tttagcaaat aattgggaaa cgtacctttt gttggcattt ttcacattac
   122101 tttctgtctt cttgtcaaaa gtagatttga aattttttat ccgaggcatt cgcccattga
   122161 tctggctaat cctcttcact gtagctttgc aggtcttgtt tacaagtggc ggagaaactt
   122221 attggagttg gggtgttttc catatcactg aatttggtgt gatgaacggc ctctttattt
   122281 tctgtcgatt cgtgttgatc atttttatgt cgactctact cacgcttact acaccgcctt
   122341 tggaattatc ggatgcgatt gagtacttgc ttcgtccatt gaaagccgta cggttcccag
   122401 tccacgaaat ttcattgatg ctgtcgattg ctcttcgttt tgtgcctaca ttgatggacg
   122461 aaacagaaaa gatcatgaac gctcagcgcg ctcgcggtgt tgattttggt gaaggaaacc
   122521 tagttcagaa aatgaaagca gtcattcctt tgctgattcc tttatttgtc agcagcttca
   122581 accgtgcgga agatcttgcg actgctatgg aagcaagagg ctacaaaggt ggggaaggaa
   122641 gaacgaaata tcgtgtattg cattggcata atagagacac gatggttatc attgcttttg
   122701 tattattaac tgtgctactg atctttttaa gaggataaac gttcagtggg ccgctatcta
   122761 ttcttttctt gctgatctgt ttgcaagaaa ggatgcaagc agtgtatgac aagaaatatt
   122821 agggtctgtg gcagactaag gtcacaggcc tctttctttt atctgaaaag aaagaacgaa
   122881 aaaattttat agaaaaatca ttattccaga taacctttta ggaacaaagg agagaaaaac
   122941 atggtacgtt acaaagcaat cattgcgtac gacggaacaa attttaatgg attccaaaaa
   123001 cagccaaatg ggcgtactgt tcaagaagaa gtagaaaaaa cattacaaaa aatggcaaat
   123061 ggaaaagaaa tcacggtctt tggttcggga aggacagatg ccggagtaca tgcgatcggg
   123121 caagtaatcc attttgatta tccagaggag cgtccgttag aacgaatgcg tttcgcgcta
   123181 gatacccagt caccagagga tattgctgta agacaagtag aaattgtttc agaagacttc
   123241 cacgcaagat atttggtcaa agaaaagacg tatcaatttc gagtggatat agggaaacca
   123301 cgcagtcctt ttcgacgcca ttatgcaagt tattttcctt acccacttga tttggaaaaa
   123361 attcagcggg cgcttcctga tttattaggg actcacgatt tcacctcttt ttgtgcatca
   123421 ggaagctcga tagaggataa aatacgtacg atctacgagg ctaagatgga ggtaaatgaa
   123481 acaaaagacg aattgttgtt tacatttagg ggaaatggct tcttgtataa gatgatacgg
   123541 atcttagtag gaacgctttt gaaaattggc aatggccgat tgcctgaaga tagtatccca
   123601 gatattattg cgaaaaaaga tcgtaatgca gcaggaccta cagcacaccc tgaaggactt
   123661 tatttgtatg aagtgaaata tgaataagag gttatgatag aagtggtcag cttcaagaaa
   123721 taagaaggta tttacgaaaa ttacttctca aaattttgca aaatttcggc ttattttcga
   123781 agaagctact tctggaacac cgtttaagaa agaggtcgtg agcctgtcat ttaactctga
   123841 gtcacaaaga gcaatttcaa aaaacagctt ctcatctttg atgaatatcg tgacttgtgg
   123901 acgaggcgtt gataagtgaa tcatcttttt gttacctatt ttttctgtaa ccaaaaaacg
   123961 atggaacgtt gttttgattg cccttggtgc ggacagtctg aacaggttcc atcgtttctt
   124021 tattttctac gtcttcttct gtgtgtgttt cgtggttgtt cttctattgc tggatcaatc
   124081 gtgccataaa aggggcgatt gcggtcaagg taccagacat aaagaataaa caatgcaata
   124141 cataggacaa aaaggattgc acctatcgta aatccttcag gcaagtaact gaaagtgaca
   124201 gtatgtttac ctgctggaac ttttatcatc aagaatgcgt ctttgaaatt gctgaccttg
   124261 actggtttcc catcaatttt agctttccat cctttgtcat aaggaatagt tgtcaccaac
   124321 atggaatctt cagcggtatt tacagtccca gaagcttttc tgccagtggc ttccatttcg
   124381 acaccttttt ctttgatctg attcattgcg gcttgatagg ctacaacatc tagaccaacg
   124441 actttaggct ccatgaaact tatttctttc gtcccataaa aacttgcagt aaatgtcact
   124501 gttgtctctt gaggataata gccaagatca tagtattgac cagaaatgtt gatttgcgtt
   124561 tttcgcgatg taccattgac agtgatcgtc gcactagaac tttctaattg cgcaaaattg
   124621 gttgggaaca aacttaagta agcttgtgta tttgcaggca catggacttc ccaagtgagc
   124681 tcttttggct ggttatctgc tgtttctgag taagtgacgc cagtcgttgt ctttgtgatc
   124741 gtcgtattca actgattctt caaagtaggt gtatagaatg taaaatactg ttcatttaga
   124801 ccagacaatg tattgatcaa gtttgtctga ctggtcaaat tatctgtcac tggctgctca
   124861 acatcattaa cggacaacgg tgcagtaaat gctagtggca atgcattgac attctgatac
   124921 agtgtatagt cgccgctttg accagcttgg cggaagccat atttactgaa cgtgctttcg
   124981 tttttagaaa tgttatattt gattcctgta aacccatcca tcagcaaagt attattgtta
   125041 taacggatat tcaaatttgt ccctcttgaa cggaaaccta atttatccag gtaagaggaa
   125101 gaattacgat ttcttataga agaaaacaaa ctgataccac tgtaaccata gttgatcgaa
   125161 tcgtttgcag atactggatc cagattttcc aagcggtaaa acgagtcgga atcttttttt
   125221 gtttcattta caagagcttt caagtcagga taaggatcag tatataaact gcgggaagca
   125281 taattccaat catcaagaat gccatggatc atactgttcg tattgaccag tgcttcagca
   125341 gacatgatca ataataacaa tatactcaga tgattgaatg aaagtttttt atgctgataa
   125401 aatcccacag caaaagcata aatccctaag aaaaccactg tcaatacaaa ggaagtcatc
   125461 gtcacatagg tgtagcttcc ttcaggtttg atgccccatg ccaccgcaaa gagagcagct
   125521 acgaccaaaa tgattcctaa caacagccca cgatcgtctt gttctatctt ttcccatcct
   125581 tttcctgcaa gcaggagcac taagaaagag aacagatagg cataacggaa taaaaacata
   125641 ttcggtgcat gcataccatg ccagaacaaa ttcaatggaa caagataaaa acttgcgata
   125701 agtatggcga aaagactgcc gtacaaaaat ttatttttca acggtacttt ccgactggca
   125761 aaataaaaca gacagaggac taatggtagc agacctgcgt aaacgaacgg aatcgatccg
   125821 tattttgtcg tgtcataaac accaatcata tttttcatga ttagatccag ataagaagtc
   125881 gcttctgttt tcaacgtagt gatctgactc agtgcctcgc catttgaccg aagatccagc
   125941 actgctggca atacaatgat cattgaagcg ccgcctgcca gtaaagaagt gataccataa
   126001 ggaacaatcg tttttttata ttctgaccag tttgtcaata gacgggcgat aaaatataag
   126061 aaagaaaata cgccaatcat aaaacccata taaaaactgg ataaaaacaa gagtaaataa
   126121 ctgataaata aaagtttcgg ccgtttaaga tccataacac gatgaatccc caaaatcact
   126181 aatggaagat aaacaaatgc atccagccac atgatgatct ccgaatgtgc agtgataaat
   126241 gagatcaatg cgtaactgac gctaagtgca acatgccccc agcgaggaat cttgaacgta
   126301 cgtgcaagaa accaaaaagc caatccggca cagccgacct taagcaaagt cagaacatac
   126361 agtgcatctg gcatcatctg gtttggaaaa aagaacacca gtggcgtgaa gatcccgcct
   126421 agatagtaag aaattaaaga taaataattc aatcctagag aagcattcca tgtataaaaa
   126481 atactttgct ttccaagaag aacatttcgg aagctggcat gaaaattaga aaactgtgaa
   126541 aaggcatcac ttgccaaaat acttctgctg cttccaggat agattccgat acttagataa
   126601 acaagtgcta aaatcaaaaa cggaatcagg aaactagctg ctgcgtagcg tccgttttct
   126661 ctaaagaatg actttaaatt ttttttcata tttattttcc accaaatttc tatgaagttg
   126721 tattcagttt atcatatcct tgtttttctc tgcttaaaaa gagtctagtt ttcacaaaaa
   126781 aataaaattt agaataaata acttcataat ttgttcgtat aacaaaaata aacgcaaaaa
   126841 aagggtagga atcaaaagtc ccacccttaa aaatttttat taaataaaaa accgttcact
   126901 atctgaacgg tccaagtatc attcaattaa acgcgttcaa cttttcctga tttcaaagca
   126961 cgagttgaca cccaaacttt tttaggtttt ccgtcgacca taacgcgaac tttttgtaag
   127021 ttaggtttaa cagtacgttt tgttgagttc atagcgtgtg aacggttgtt tccacttttt
   127081 gtcttgcgac ctgtaaagta acaaactttt gccatggtaa tttcctcctt tgccttgatt
   127141 tggagcaata gaataattca gctcatacca gactaacata tcatatagaa tgggaatttg
   127201 caagtacatt ttcatagata caattgacaa ttgagaagaa taattgtaaa ttaaacaagg
   127261 ttatacctga aattttgcaa ggtttttgag tactttgggt aactgccttt tatttcaagt
   127321 tgcgctatga taaaatatga tagaagaaaa atgggagttt tttacccgtt aaggaggctc
   127381 attcatggct gtaaaaattc aaacgtcagc tggaaccatt gaaattacca atgatgtaat
   127441 tgcaacagtt gttggtggcg ccgcgacaga tgtgttcggt gttgtaggaa tggccagcaa
   127501 aaatcaaatt aaagataata ttactgagat tttgcgtaaa gaaaattact caagaggagt
   127561 agttgtccgc caagaagata atggtattgc tgtagatgtt tatacgatta tcagctatgg
   127621 tacgaaaatc tctgaagttt cccgcaacgt ccaagaaaaa gtgaaataca atctagaggc
   127681 attattaggc gtaactgcca attcagttaa tgtctttgta caaggtgttc gtgtactgcc
   127741 agactaggca ggagactggc tggtaactca gcagtcgatc tgaaggagga ttatctaggt
   127801 gagtgtaaca gaaataagtg caagccagtt ccaggaaatg gtccaggcag gtgcgaatcg
   127861 tctgcaagta aatgcagaat acgtcaattc attaaatgta ttccctgtgc cagatggcga
   127921 tacgggaaca aatatgaatc tatctatgac tagtggagct aaggcagtag tagattcaac
   127981 ctcagaaaaa gtaggagaat tagcagcaat gctttcaaaa ggattgctga tgggtgcgcg
   128041 cggaaattcc ggcgttattt tgtctcaatt gtttcgtgga ttttctaagc aaattccaga
   128101 tgttgtctca ttaaatgctt ctgatcttgc tgcagccttc actcatggag ttgaaactgc
   128161 gtataaagca gtaatgaaac cagtagaagg aacgattttg acagtagcta gagaagcagc
   128221 gaaagctgga gaaaagaaag caaaaagtac tgatgatgtc gttgaagtaa tgacagctgt
   128281 tgtaaaagga gcaaagcgtg ctttagctaa aactccagac ttgcttccag tcctaaaaga
   128341 agtcggtgtc gtagacagtg gagggcaagg actgctgttt gtttatgagg gctttttaag
   128401 tgcattgaat ggagaattcc aagcggatga aacatatgaa ccttctccag cagaaatgga
   128461 tgatatggtc aatgcagaac atcatcgcag tgtccaaggt caaatggcga cagaagatat
   128521 ccattttggt tactgtacag aaatcatggt aaaaatcgga gaaggaccta cagtcgatag
   128581 tacattcgat tacgaagaat tccgtaacta tttagatggt ataggagatt ctttacttgt
   128641 ggtcaatgat gacgagatca tcaaagtcca cgtccataca gaaaacccag gagaagtctt
   128701 gaattatgga caaaaattcg gttcattagt caaaatcaaa gtcgacaaca tgcgcttgca
   128761 gcatgagacg attttggaac acgatgaaga agtgaacgag tttgcgaaaa aagaaatacc
   128821 acgtatcccg tatggtatcg tagcgatcgc tgctggtaaa ggcgtccaag agctgtttga
   128881 aagtttaggc gctaattatg ttatcagtgg tggacaaaca atgaatccaa gtacggaaga
   128941 cattgttaaa gcgattcaag aagtaaacgc agataaagtg attgtcttgc caaacaataa
   129001 gaacatcttc atggcagctg atcaagcagc agaagtagca gatatcccag tagcagttgt
   129061 tccttcaaga acgatttccc aaggattgac agctatgctt tcattcaatg atcaagcttc
   129121 tttagaagaa aacaaagaaa cgatgacaga aatgttgtct agcgttgtga gcggtcaagt
   129181 cactcacgcg atcagagata cctcaattga cggtgtagag atcaaagaag gagacttttt
   129241 gggcatgatc gatggaaaaa tcctgatctc taacccagat atcacagcaa cagcgttaag
   129301 tacactagaa caaatgatca atgaggacac agagatcgta acgatcttgg caggtgatga
   129361 aggaacagtt gaacaagcaa atgaatttgc tgagaaacta acagaaaaac atcctgattt
   129421 ggaaatcgag atccaccaag gagatcagcc tgtctatcct tatctatttt ctgctgaata
   129481 atttctgtgt cagaatatct ttctaacaca gtattcattc ataaaaggcc ttcggttagt
   129541 gatcaggtat gatcgctgac caagtccttt ttttgttaaa ggagggagga aaaatttatg
   129601 cgttctttag atgatccaat cactatgctg gcaggagtcg gagaaaaaag agcagctagt
   129661 cttgccagct tgggcatcca aacgattgaa gacttactga cttattatcc ttttcgctac
   129721 gaagatattc aggaaagaaa tctaaacgag atccaggatc aagaaaaggt tactttgaaa
   129781 ggaatcgtag tctcgcctcc tgtgatgaat cgatttggtt ataaaaaaag ccgattgcaa
   129841 tttcgtatga tgcaagaaca tgatgtgttc aacgtttctt tttttaatca accttatcta
   129901 aaagaaaaag tcattttatc ggaggaaatc gccgtatacg gtaaatggga tgcaaagcgt
   129961 aaagccttga acgggatgaa gattttaggt tctcaaacaa tggatgactt ttcgccgata
   130021 tatcacgtca acaaatcaat tcgtcaaacg acattagttg atctaatcaa aaaagggttt
   130081 caagaatacg gcacattgat tgaagaaaat ctgccaaaca accttgtgga gaaatatcga
   130141 ctgcttgacc gagcttctgc tgtaagaagt atgcattttc caaaagacca cgaagaaaac
   130201 catcaagcca aacgacgtgt cgtttttgaa gagttctttt tatttcaaat gcgtcttcaa
   130261 ggattgaaaa aagcagaaaa agcagaaacg aatggtttgg agatccttta tgatgtccaa
   130321 aaattgaaac aatttactca aaagctacct tttgaactga caaatgcaca aaaacgtgta
   130381 acgaatgaaa tctgtcggga tcttcgcagt ccgcagcata tgcagcgact tttgcaggga
   130441 gatgtaggta gcggaaaaac agtggttgcc gcgattgcgt tatacgctac cgttacagca
   130501 ggtttccaag gtgcgttgat ggtgcctaca gaaatcttgg cacaacaaca tatggaaagc
   130561 ttgcaacagc tgtttgatcc caatgaagta accatcgcat tgattacggg gtcaacgaaa
   130621 gcaaaagaac gacgtgagct ccttgaaaaa ctagagcaag gggaaattaa cgtcgtgatc
   130681 ggcacacatg cattgatcca agatggagtc gaatttcaga atttaggtct agttattacg
   130741 gatgagcagc accgttttgg cgtgaaccag cggaaagtac ttcgtgaaaa aggctggcga
   130801 ccagatgtct tatttatgac agcgactccg attcctagaa cattagctat tacagcatat
   130861 ggtgagatgg atgtatctat cattgatgaa cttccagctg gacgtatccc gatcgaaaca
   130921 cgctgggtaa gaacacctca attggacagt gtactggatt ggacgaaaaa agaactggca
   130981 agaggacatc aaatgtatgt catctgtccg ctgattgaag aatcagaagc attagatgta
   131041 aaaaatgcag tggaaatcta tgaaaaactt cgtgaactat ttgcaccaaa atatgaagtt
   131101 ggcttgttac atggtaaaat gaagaatcag gaaaaagaag taatcatgga agccttcaaa
   131161 gacaaccaga tgcagatatt agtttcgact actgtaattg aagtaggggt aaacgtgccg
   131221 aacgcgaccg tcatgctgat catggatgcg gatcgatttg gattggcaca gctgcaccaa
   131281 cttcgtggac gtgttggacg cggaagtgat gcttcctact gtatcttagt tgctaatcct
   131341 aaaaatgaac taggtgtgga acggatgaaa atcatgacag agaccaccaa tggttttgta
   131401 ctaagcgaaa aagatctgga attacgtggt cctggtgaag tatttggctt ccgtcaatct
   131461 ggtctgcctc aatttgcgat tgctgacttg gtgacggatg gaaatgtttt ggaggtagcc
   131521 agagaagagg ctgcagccct ttggcaaata aaggattggc agatgcttcc tgagtatcag
   131581 cctttagcgc aaagcctcca aatagaaaat caggataatc gttatttcga ttagcagact
   131641 gtgctatact ttatactgat gacggaaaaa ggagtggaaa caatgaaaat tgccgtagat
   131701 gcaatgggcg gagatcacgc acctcaagca attgtagaag gcgtggcttt agcgcagcaa
   131761 gattttccag aagtagaatt cttactttac ggaaaagaag cagaaatcaa gaaatactta
   131821 acaaatgaaa aaaacatcac gattatccat acagacgaaa aaatcaatag tgatgatgag
   131881 ccagtaaaag caattcgacg aaaaaagact gcatcaatgg tccttgctgc acaagcagtg
   131941 aaaaacggtg aagcagatgc tgtattttca gcagggaata caggcgcgct actagcagca
   132001 gggttgttca tcgtaggacg tatcaaaaat atcgaacgcc ctggcttgat gtctaccttg
   132061 ccagtagtag ggaaagaagg tgccggtttc gatatgctgg atcttggcgc taacgcagaa
   132121 aacaaaccag aacatttgtt gcaatacggt attttaggtt ctttttatgc acgtaaagtc
   132181 cgaggtatcg gacgtcctcg tgtcgcactc ttaaacaacg gaacagaagc aacaaaaggt
   132241 agtgaagtga cgaaaaaagc ctatgaactc cttcagaatg aaacaagctt gaattttatt
   132301 ggaaacgtag aagctcgtga gctactcaat ggtgtggctg atgtagtggt cacagatgga
   132361 tttacaggca acgctgtttt gaaatctatt gaaggaacag caatgaatat gatgaatcta
   132421 ttaaaatctg ctattctaaa tgaagggatc aaaggaaaaa tgggcgctat gcttttaaaa
   132481 gacggcttac gttctttgaa agcagaaatg gattattcca aacatggcgg tgccgttttg
   132541 tttggcttga aagcaccagt cattaaaact catggagcaa caggccccga tgctgttcgc
   132601 tatacgatcc gccaaatcca cacaatgctt gagacagatg tagttggaca attagtcgaa
   132661 caatttgaaa aaagcgaaga atagtatttg gatatctgaa gcgatccgtt ccattgaaaa
   132721 aaaggtggac attcctgaaa aatgccagta aaattagcca tggtgtaggt aattgacaag
   132781 tgtatgattc ttggaggtga aaaagttgac tcgcgaagaa gtatttaaca aagtagcgaa
   132841 aattatttca aatcattttg agatagatac cgataaagtg acggatgaat tgaacatcaa
   132901 agatgattta aaagctgatt caattagtat tatggaattc gttttagagc ttgaagatga
   132961 attcggtacg gaaatttcag atgaagacgc tgaacaaatt gaaacagtcg gtggcgcagt
   133021 agattatatc agcagccatc ttaaataatt tcaaataaaa gcaaagaagg ataaaaagct
   133081 gcatgcag
//
LOCUS       DARPZF010000003       106749 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.003, whole genome shotgun sequence.
ACCESSION   DARPZF010000003 DARPZF010000000
VERSION     DARPZF010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 106749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 106749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..106749
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.003"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(715..3864)
                     /locus_tag="SLE65_000305"
     CDS             complement(715..3864)
                     /locus_tag="SLE65_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEI8447631.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYNTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3878..5122)
                     /locus_tag="SLE65_000306"
     CDS             complement(3878..5122)
                     /locus_tag="SLE65_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEI8447632.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELIKFKLEPGDFIMSGAGTIGRIS
                     RVPKQIKPGVFNQALIRLRINKEITDSEYFIQFIRADFMQRKLTGANPGSAITNLVPM
                     SEVKKWIVQFPILEEQKKIGNFFKQLDDTIALQQRKLDLLKETKKGFLQKMFPKNGAK
                     VPEIRFPGFTEDWEQRKFKEFSKKTGKKNTKDLDFPAYSVSNKAGLISQTEQFDGSRL
                     DDLEKTNYKFVEPNEFAYNPARVNVGSIAFNNLGMTVIVSSLYVVVKMSEDLDNEFIL
                     QFIKSPTFIKEVKRNTEGSVREYLFYENFANIKFPFTRNKEEQQKIGAFFKQLDDTIA
                     LHQRKLDLLKETKKGFLQKMFV"
     gene            complement(5115..6707)
                     /locus_tag="SLE65_000307"
     CDS             complement(5115..6707)
                     /locus_tag="SLE65_000307"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEI8447633.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(7216..7941)
                     /locus_tag="SLE65_000308"
     CDS             complement(7216..7941)
                     /locus_tag="SLE65_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447634.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(8095..8421)
                     /locus_tag="SLE65_000309"
     CDS             complement(8095..8421)
                     /locus_tag="SLE65_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447635.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(8458..8823)
                     /locus_tag="SLE65_000310"
     CDS             complement(8458..8823)
                     /locus_tag="SLE65_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HEI8447636.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(8860..9075)
                     /locus_tag="SLE65_000311"
     CDS             complement(8860..9075)
                     /locus_tag="SLE65_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8447637.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            9204..9539
                     /locus_tag="SLE65_000312"
     CDS             9204..9539
                     /locus_tag="SLE65_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8447638.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(9615..11612)
                     /locus_tag="SLE65_000313"
     CDS             complement(9615..11612)
                     /locus_tag="SLE65_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447639.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(11710..11985)
                     /locus_tag="SLE65_000314"
     CDS             complement(11710..11985)
                     /locus_tag="SLE65_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8447640.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            12217..12951
                     /locus_tag="SLE65_000315"
     CDS             12217..12951
                     /locus_tag="SLE65_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8447641.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            12990..14132
                     /locus_tag="SLE65_000316"
     CDS             12990..14132
                     /locus_tag="SLE65_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEI8447642.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(14227..15618)
                     /gene="sufB"
                     /locus_tag="SLE65_000317"
     CDS             complement(14227..15618)
                     /gene="sufB"
                     /locus_tag="SLE65_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEI8447643.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(15623..16093)
                     /locus_tag="SLE65_000318"
     CDS             complement(15623..16093)
                     /locus_tag="SLE65_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEI8447644.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(16080..17315)
                     /locus_tag="SLE65_000319"
     CDS             complement(16080..17315)
                     /locus_tag="SLE65_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEI8447645.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(17312..18598)
                     /gene="sufD"
                     /locus_tag="SLE65_000320"
     CDS             complement(17312..18598)
                     /gene="sufD"
                     /locus_tag="SLE65_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEI8447646.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(18611..19384)
                     /gene="sufC"
                     /locus_tag="SLE65_000321"
     CDS             complement(18611..19384)
                     /gene="sufC"
                     /locus_tag="SLE65_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEI8447647.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(19581..20429)
                     /locus_tag="SLE65_000322"
     CDS             complement(19581..20429)
                     /locus_tag="SLE65_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEI8447648.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(20453..21139)
                     /locus_tag="SLE65_000323"
     CDS             complement(20453..21139)
                     /locus_tag="SLE65_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8447649.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(21132..22166)
                     /locus_tag="SLE65_000324"
     CDS             complement(21132..22166)
                     /locus_tag="SLE65_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8447650.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(22229..22485)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(22561..22899)
                     /locus_tag="SLE65_000325"
     CDS             complement(22561..22899)
                     /locus_tag="SLE65_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HEI8447651.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(22901..23257)
                     /locus_tag="SLE65_000326"
     CDS             complement(22901..23257)
                     /locus_tag="SLE65_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEI8447652.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(23263..24450)
                     /locus_tag="SLE65_000327"
     CDS             complement(23263..24450)
                     /locus_tag="SLE65_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEI8447653.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(24641..25486)
                     /locus_tag="SLE65_000328"
     CDS             complement(24641..25486)
                     /locus_tag="SLE65_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEI8447654.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            25720..26685
                     /locus_tag="SLE65_000329"
     CDS             25720..26685
                     /locus_tag="SLE65_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEI8447655.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            27062..28105
                     /locus_tag="SLE65_000330"
     CDS             27062..28105
                     /locus_tag="SLE65_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HEI8447656.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(28167..28631)
                     /locus_tag="SLE65_000331"
     CDS             complement(28167..28631)
                     /locus_tag="SLE65_000331"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEI8447657.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            28877..29824
                     /locus_tag="SLE65_000332"
     CDS             28877..29824
                     /locus_tag="SLE65_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEI8447658.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(30035..32107)
                     /locus_tag="SLE65_000333"
     CDS             complement(30035..32107)
                     /locus_tag="SLE65_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEI8447659.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(32040..32417)
                     /locus_tag="SLE65_000334"
     CDS             complement(32040..32417)
                     /locus_tag="SLE65_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEI8447660.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(32546..33124)
                     /locus_tag="SLE65_000335"
     CDS             complement(32546..33124)
                     /locus_tag="SLE65_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEI8447661.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            33256..34548
                     /locus_tag="SLE65_000336"
     CDS             33256..34548
                     /locus_tag="SLE65_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEI8447662.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(34608..35726)
                     /locus_tag="SLE65_000337"
     CDS             complement(34608..35726)
                     /locus_tag="SLE65_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEI8447663.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(35740..37161)
                     /gene="arcD"
                     /locus_tag="SLE65_000338"
     CDS             complement(35740..37161)
                     /gene="arcD"
                     /locus_tag="SLE65_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HEI8447664.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(37407..38528)
                     /gene="mnmA"
                     /locus_tag="SLE65_000339"
     CDS             complement(37407..38528)
                     /gene="mnmA"
                     /locus_tag="SLE65_000339"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEI8447665.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            38932..39531
                     /locus_tag="SLE65_000340"
     CDS             38932..39531
                     /locus_tag="SLE65_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEI8447666.1"
                     /translation="MNYFISDMHFFHEHLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(39669..40955)
                     /gene="efmA"
                     /locus_tag="SLE65_000341"
     CDS             complement(39669..40955)
                     /gene="efmA"
                     /locus_tag="SLE65_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HEI8447667.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(41226..41570)
                     /locus_tag="SLE65_000342"
     CDS             complement(41226..41570)
                     /locus_tag="SLE65_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEI8447668.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(41707..42852)
                     /locus_tag="SLE65_000343"
     CDS             complement(41707..42852)
                     /locus_tag="SLE65_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEI8447669.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(43032..44006)
                     /locus_tag="SLE65_000344"
     CDS             complement(43032..44006)
                     /locus_tag="SLE65_000344"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEI8447670.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(44086..44961)
                     /locus_tag="SLE65_000345"
     CDS             complement(44086..44961)
                     /locus_tag="SLE65_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HEI8447671.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            45091..46998
                     /locus_tag="SLE65_000346"
     CDS             45091..46998
                     /locus_tag="SLE65_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HEI8447672.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(47539..50817)
                     /locus_tag="SLE65_000347"
     CDS             complement(47539..50817)
                     /locus_tag="SLE65_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HEI8447673.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(51088..51633)
                     /locus_tag="SLE65_000348"
     CDS             complement(51088..51633)
                     /locus_tag="SLE65_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEI8447674.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(51645..52337)
                     /locus_tag="SLE65_000349"
     CDS             complement(51645..52337)
                     /locus_tag="SLE65_000349"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEI8447675.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(52356..52640)
                     /locus_tag="SLE65_000350"
     CDS             complement(52356..52640)
                     /locus_tag="SLE65_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447676.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(52653..53216)
                     /locus_tag="SLE65_000351"
     CDS             complement(52653..53216)
                     /locus_tag="SLE65_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEI8447677.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            53444..54106
                     /locus_tag="SLE65_000352"
     CDS             53444..54106
                     /locus_tag="SLE65_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HEI8447678.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            54230..55426
                     /locus_tag="SLE65_000353"
     CDS             54230..55426
                     /locus_tag="SLE65_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEI8447679.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(55527..56903)
                     /locus_tag="SLE65_000354"
     CDS             complement(55527..56903)
                     /locus_tag="SLE65_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8447680.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(56940..57806)
                     /locus_tag="SLE65_000355"
     CDS             complement(56940..57806)
                     /locus_tag="SLE65_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HEI8447681.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(57895..58920)
                     /locus_tag="SLE65_000356"
     CDS             complement(57895..58920)
                     /locus_tag="SLE65_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEI8447682.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(58938..59612)
                     /locus_tag="SLE65_000357"
     CDS             complement(58938..59612)
                     /locus_tag="SLE65_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8447683.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(59796..60689)
                     /locus_tag="SLE65_000358"
     CDS             complement(59796..60689)
                     /locus_tag="SLE65_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEI8447684.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(60763..62460)
                     /locus_tag="SLE65_000359"
     CDS             complement(60763..62460)
                     /locus_tag="SLE65_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEI8447685.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(62453..63766)
                     /locus_tag="SLE65_000360"
     CDS             complement(62453..63766)
                     /locus_tag="SLE65_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HEI8447686.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(63766..67284)
                     /locus_tag="SLE65_000361"
     CDS             complement(63766..67284)
                     /locus_tag="SLE65_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HEI8447687.1"
                     /translation="MDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEK
                     KEISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMV
                     NFYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETL
                     YKDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDV
                     LFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGS
                     SNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAI
                     GRNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVS
                     PFGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYK
                     FSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSS
                     SIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFET
                     KMPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEY
                     TSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNI
                     NKLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDG
                     KYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRL
                     YDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTL
                     DGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQP
                     LHLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIID
                     GVLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPND
                     SSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTL
                     KVEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYIL
                     LAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(67577..68035)
                     /locus_tag="SLE65_000362"
     CDS             complement(67577..68035)
                     /locus_tag="SLE65_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEI8447688.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(68333..68851)
                     /locus_tag="SLE65_000363"
     CDS             complement(68333..68851)
                     /locus_tag="SLE65_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEI8447689.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(68853..69470)
                     /locus_tag="SLE65_000364"
     CDS             complement(68853..69470)
                     /locus_tag="SLE65_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEI8447690.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSFYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(69467..70321)
                     /locus_tag="SLE65_000365"
     CDS             complement(69467..70321)
                     /locus_tag="SLE65_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEI8447691.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(70318..71229)
                     /locus_tag="SLE65_000366"
     CDS             complement(70318..71229)
                     /locus_tag="SLE65_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8447692.1"
                     /translation="MKRLSIRKKKEARWAYLFISTFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(71270..72604)
                     /locus_tag="SLE65_000367"
     CDS             complement(71270..72604)
                     /locus_tag="SLE65_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEI8447693.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            72812..73642
                     /locus_tag="SLE65_000368"
     CDS             72812..73642
                     /locus_tag="SLE65_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HEI8447694.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(73886..74204)
                     /locus_tag="SLE65_000369"
                     /pseudo
     CDS             complement(73886..74204)
                     /locus_tag="SLE65_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(74326..74520)
                     /locus_tag="SLE65_000370"
     CDS             complement(74326..74520)
                     /locus_tag="SLE65_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447695.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(75025..75210)
                     /locus_tag="SLE65_000371"
     CDS             complement(75025..75210)
                     /locus_tag="SLE65_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447696.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(76060..76401)
                     /locus_tag="SLE65_000372"
     CDS             complement(76060..76401)
                     /locus_tag="SLE65_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HEI8447697.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(76401..76631)
                     /locus_tag="SLE65_000373"
     CDS             complement(76401..76631)
                     /locus_tag="SLE65_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEI8447698.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            76918..77256
                     /locus_tag="SLE65_000374"
     CDS             76918..77256
                     /locus_tag="SLE65_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447699.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(77461..77700)
                     /locus_tag="SLE65_000375"
     CDS             complement(77461..77700)
                     /locus_tag="SLE65_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HEI8447700.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(77676..78023)
                     /locus_tag="SLE65_000376"
     CDS             complement(77676..78023)
                     /locus_tag="SLE65_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HEI8447701.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(78755..79336)
                     /locus_tag="SLE65_000377"
     CDS             complement(78755..79336)
                     /locus_tag="SLE65_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEI8447702.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLVKERLLTSQKVL"
     gene            complement(79519..80145)
                     /locus_tag="SLE65_000378"
     CDS             complement(79519..80145)
                     /locus_tag="SLE65_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEI8447703.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(80167..81498)
                     /locus_tag="SLE65_000379"
     CDS             complement(80167..81498)
                     /locus_tag="SLE65_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEI8447704.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(81653..82054)
                     /locus_tag="SLE65_000380"
     CDS             complement(81653..82054)
                     /locus_tag="SLE65_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HEI8447705.1"
                     /translation="MKKAYETAMINHGGRNGEVEEPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVFEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(82140..82346)
                     /locus_tag="SLE65_000381"
     CDS             complement(82140..82346)
                     /locus_tag="SLE65_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447706.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(82441..83943)
                     /locus_tag="SLE65_000382"
     CDS             complement(82441..83943)
                     /locus_tag="SLE65_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HEI8447707.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(83961..84416)
                     /gene="argR"
                     /locus_tag="SLE65_000383"
     CDS             complement(83961..84416)
                     /gene="argR"
                     /locus_tag="SLE65_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEI8447708.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(84514..85131)
                     /locus_tag="SLE65_000384"
     CDS             complement(84514..85131)
                     /locus_tag="SLE65_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HEI8447709.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            85352..86725
                     /locus_tag="SLE65_000385"
     CDS             85352..86725
                     /locus_tag="SLE65_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8447710.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            86800..87912
                     /locus_tag="SLE65_000386"
     CDS             86800..87912
                     /locus_tag="SLE65_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEI8447711.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(87984..89621)
                     /locus_tag="SLE65_000387"
     CDS             complement(87984..89621)
                     /locus_tag="SLE65_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HEI8447712.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAVVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(89789..90397)
                     /locus_tag="SLE65_000388"
     CDS             complement(89789..90397)
                     /locus_tag="SLE65_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEI8447713.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(90782..91933)
                     /gene="queG"
                     /locus_tag="SLE65_000389"
     CDS             complement(90782..91933)
                     /gene="queG"
                     /locus_tag="SLE65_000389"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HEI8447714.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(91952..92704)
                     /locus_tag="SLE65_000390"
     CDS             complement(91952..92704)
                     /locus_tag="SLE65_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447715.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKNADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(92845..93794)
                     /locus_tag="SLE65_000391"
                     /pseudo
     CDS             complement(92845..93794)
                     /locus_tag="SLE65_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
     gene            complement(93795..94634)
                     /locus_tag="SLE65_000392"
     CDS             complement(93795..94634)
                     /locus_tag="SLE65_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEI8447716.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(94631..95377)
                     /locus_tag="SLE65_000393"
     CDS             complement(94631..95377)
                     /locus_tag="SLE65_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEI8447717.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            95615..96985
                     /locus_tag="SLE65_000394"
     CDS             95615..96985
                     /locus_tag="SLE65_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8447718.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(97040..97936)
                     /locus_tag="SLE65_000395"
     CDS             complement(97040..97936)
                     /locus_tag="SLE65_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEI8447719.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(98050..98220)
                     /locus_tag="SLE65_000396"
     CDS             complement(98050..98220)
                     /locus_tag="SLE65_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447720.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(98217..98894)
                     /locus_tag="SLE65_000397"
     CDS             complement(98217..98894)
                     /locus_tag="SLE65_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEI8447721.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(98985..99890)
                     /locus_tag="SLE65_000398"
     CDS             complement(98985..99890)
                     /locus_tag="SLE65_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEI8447722.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     KNFKNIALDTLKKQLEKQTTVSWTT"
     gene            100065..101519
                     /locus_tag="SLE65_000399"
     CDS             100065..101519
                     /locus_tag="SLE65_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8447723.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVDPSH"
     gene            101535..102566
                     /locus_tag="SLE65_000400"
     CDS             101535..102566
                     /locus_tag="SLE65_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEI8447724.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGHFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            102573..103760
                     /locus_tag="SLE65_000401"
     CDS             102573..103760
                     /locus_tag="SLE65_000401"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEI8447725.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            103916..105298
                     /locus_tag="SLE65_000402"
     CDS             103916..105298
                     /locus_tag="SLE65_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HEI8447726.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            105270..105656
                     /locus_tag="SLE65_000403"
     CDS             105270..105656
                     /locus_tag="SLE65_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447727.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(105856..106524)
                     /locus_tag="SLE65_000404"
     CDS             complement(105856..106524)
                     /locus_tag="SLE65_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEI8447728.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT        30578 a        22269 c        18797 g        35105 t
ORIGIN      
        1 ctaatacagg tagtcctctt ttttgttatt ttgatattct aaatcatttt ttattggatt
       61 attcccttgt tcgatataga cccaaattga tctatcaata attatcaaac tgagtcatat
      121 agagacaaaa atttcaaaaa tgacctgtta aatggtcatc gaatatcatt taaaatcaat
      181 acgacggagt cagacacgga gtcaaaacaa gcccgctgag agtaaaaaat atatacagtc
      241 ccataggtaa agtgccacag gactgtatat ttttttattt gagattacct gaaatgattc
      301 catttacttt ttatctcatt ttttcctact agttagtatc aaatactctc ctattttctc
      361 aataaactat tttgggttac atggtatctg aaacagctaa aaccttgtca ttacagcaaa
      421 aaatcacttt atctccgttt catttcagat acatttcact taagcggatt ccaaaaaaac
      481 aaaagaaaaa ggaaccccta gttagcctat gctttttatt ggttcctctc aaaacacggt
      541 catataacaa cggggtgggg taaatgaatg aaaaaggtgg aggaaacatt attcaatagc
      601 tgtcttaaat acttcgttat aaaatgtgaa caaataaaag acatctatcc ctattttcta
      661 cacttccact ttactaccat ctttgaatcg tacaattttc ttaactcttc tcgtttacct
      721 caattcattt tcaagtggaa tcagctcatc atctaacatt ttacgccatg ctcgcttcat
      781 ttcttgtggg tatttaaatg gcttcgcttc tggatggttg gctttatatc cttcgtaatc
      841 cttactgttg ataattgctt tcatattagg aattggatct tcacctggca tatattgcag
      901 attagaagca tgtaattctt tctcagaaac aaaccactca ttggaaaaga catgaatcaa
      961 atcatcactc gcttgtgtaa aatagcgacg tttaatgaca aagatatctt cattactatc
     1021 taaagtcccc acatcaaacg catttaaaat ttgtcggtaa acttctttga ctccttctgt
     1081 tttattcaat ttagccaaag ctttttcaat ttcttctcgt gcatctgaac tattcgccgc
     1141 ataagttcct agtaattgat caatataagt agaatcaata tcatacaact tcgtggtatt
     1201 ttcactataa aattcgatcg tggaaaaatc ttctccctct ttttctggtt cttcctctat
     1261 taatgaaccc ttcacggtct cgtacacgcc aatttgttct tccaaaagtt gaatttgatt
     1321 gttcaaggtt gaagatttca ccatgtcatc attgtaatcg tcataagtca ctaacgattc
     1381 ataagcacga ttcaattctt ggaatgcttt gacgtactcg atacggattt caagtggcgt
     1441 atgttcatca atggattcca tggatgaaac ctcttttaac ttaccatatg cttgcttgaa
     1501 tctttttttg gattcctgat aacttggata aatcaaaccc gattcttctt ttgcttctga
     1561 atacagtttt gtcgcatcct cgacattctt ctccattgtg gctggctttc ggaaagtaac
     1621 aattagtcct tttgtttttt ctggatacgt acggttcgta cgtgaaaaag cttggatcaa
     1681 tcctgcatac tctagattac gatccacaaa tagggtttga atcgtaggtg cgtcaaaacc
     1741 tgtcaataga cgatccacta cgatcactaa atcaatttgt ttcccaaatt gtttgaattc
     1801 cgctcttttt cgtgccaaac gattattgat gtctccgtta taacgctcaa tgtctgctaa
     1861 tgaccaggaa gtattataat actgattata ttcctcaata attttttgca tttcttcttg
     1921 ttggacactt gaatctcggc tgttttcttc taatgaatag gtaatagcga ttcgtggaaa
     1981 atcaggatcc tccatcgttc ttccttcacg aatgggctga ttaggaaact cttttgttaa
     2041 ccagtcaggt tctttcgtca tttctttgat cgctcgataa tactttttgg ccatgtcaat
     2101 ggaactcgtg gttaagatcg cagacttcgt tggacggcca tttcgaaaat caaattttgt
     2161 ataggcattg tctggacgga acattttatg aatgactttt tggatatgtt catctgcttc
     2221 aaaaacagta gggtccaaat aactttcttt tttgacaggc tccatttgat caatcatacg
     2281 attgatctgt tccggtgaat actctgcata tgtttctact tcttttaatt tccgatagat
     2341 tttattctct aatgaagtcg gctccacggt gttttcatgc tctacttgaa atcctaaaac
     2401 cgagccatct tctaatgcat tcttgatggt ataggtatgc aagacctctc catactgatc
     2461 atgggtcgta cgtgccaatt gccctttggc ttgtttccga ttctcaggga aaatcggtgt
     2521 acctgtaaag ccaaaccaag tggatttcgg aaacattttt ttgatttctt ccatattttc
     2581 agcacttaac gctcgatgac actcatctac tacaaacacg atatgttgcc ccattaattt
     2641 ttggaagcga ttggttcctt ttttctcttc ttgttttttt gcatatttca acgccgcatc
     2701 tagcttttga cgggttgtaa taatcacaac atttgcattg gcatctgcca acagagtttc
     2761 acttaactct ttggcacttc ctgttcccac gatcaagcta ttcgctttgg cgttcccgga
     2821 agaaatccca gtattaaatt ccgaagcaaa tttcgtaaac tctgtggtgg tttgattatc
     2881 taaatctttg cggtccacta acatgatcgt ccgatcgatc cccgattttc gtgctaaaag
     2941 cttagtagat acaaaactag tcaacgtttt tcctgaacca gtcgcatgcc acacatatcc
     3001 tgattgatgt ttatttgcag caataaacaa ggcttgaatc gcatgtactt gataaggatg
     3061 taacaccatg aggattttat tgtcttgatc ttcactgaca atcgtataat ccgcaatcaa
     3121 gcgatgagca tccgggatat ttagcacttg tttgcaaaac tcatataagt tttctacctt
     3181 tttattatct ttcgttcgcc aactaaataa aaacttagga tgcaaatcct ttggtaaggc
     3241 atttgcaaaa taccgagtgg tttgttcatt ggaaaccaca aacaactgta aggtcgaaaa
     3301 gatattgttc cgaaacatac cttcttctgc atattttttg atttggttaa acgcctgata
     3361 aaaactatct tttgcggtta cttgtttcag ctcgatttgg acaatcggta atccattgat
     3421 cagtaaggtg acgtcaaaac gtcgatcccg tgcttctatg ttacttccac gttttgcaat
     3481 ttgatggacc acttcatagg tagagattcc tccaccaatg tcttgattag aataaagaat
     3541 gagcgagaca gaacccagtt gcggatcttc ccgttcaatc gtgatccgag ccattccatt
     3601 ttcacctttt aaccatttcg cagcatcaaa gggggttttc gttcgtagta acaattctgt
     3661 tttgatcgtt tcaaattctt tatcggtcaa aggaaaatca ttcagttctg cttgattatt
     3721 tgagatgatt ttttggcgta aattgaccca aagatcttct tctgatttta gatcgggacg
     3781 atacgtccac tgattatgcc cttcccccaa tacacggatc aactgttctt cgacttccgc
     3841 ttcctcacgg tgactaattt tcatttatct tccctcccta aacaaacatc ttttgtaaga
     3901 agcctttttt cgtttccttc agcaaatcta acttacgttg atgaagagcg atcgtgtcgt
     3961 cgagttgttt gaagaaagcg ccgatttttt gttgttcctc tttattccta gtaaaaggaa
     4021 acttgatatt agcgaaattc tcatagaata agtattctcg tacgcttcct tcagtgttgc
     4081 gcttgacctc tttgataaat gttggtgact tgataaactg aagtatgaac tcattatcta
     4141 agtcctcgct cattttcaca actacataaa gagagctaac aatgaccgtc ataccaagat
     4201 tgttaaatgc aattgatcct acgtttactc ttgctggatt ataggcgaat tcatttggtt
     4261 caacgaattt ataatttgtt ttttctaaat catccaacct actaccatca aactgttctg
     4321 tttgagaaat taaacctgct ttattactta ccgaataggc agggaagtct aaatctttcg
     4381 tgttcttttt tccagtcttc ttactaaact ctttgaactt acgctgttcc caatcttccg
     4441 taaatccagg aaaccgaatt tctggcactt ttgctccgtt tttagggaac attttttgta
     4501 agaatccttt tttcgtttcc tttaataaat ctagcttacg ttgttgaaga gcgatagtgt
     4561 cgtccagttg tttgaagaag ttcccaattt tcttttgttc ttctaatatt ggaaattgta
     4621 ctatccattt tttcacttct gacattggta cgagatttgt aattgctgaa cctggattag
     4681 ctcctgtgag ttttctttgc ataaaatctg cacgaataaa ttgaataaaa tattctgaat
     4741 ctgtgatttc tttatttatt ctaagtctaa tcaaagcctg attgaataca cccggtttta
     4801 tttgctttgg tactcttgaa attctcccaa ttgttccagc gccactcatg ataaaatcgc
     4861 ctggttctaa tttaaatttg attaattcat tatatttttt ttcagtaatt ttatatcttg
     4921 tttcgtaatt atcataaata gcattttgtt gttcatagac aacaaaattg ctattagata
     4981 caaagaattc tttctttaag gcactcccaa atggtcccct ccttactcca tcttttttat
     5041 caagtaagca ttcaaactta cgctgttccc aagcttccgt aaatcctggg aaacgaattt
     5101 ctggttgtat atcattactc atgtttgaac acctccagcg caccttgtaa ccacgcttca
     5161 ttttcaggtg ttgtttgcag ggaagagata gcttctaaaa gttctttttc tagcacttgc
     5221 tgttcttgtc gtatcttctt gatgtcattt ccgacatgaa ccatatcaat tggttcttct
     5281 tcttcaaacg tatctacata gcgtggaata tttaagttat agtcattttc tttgatttca
     5341 tcaaagtttg ccaaatgagc gtatttctcg acatcttttc tttcagcata ggtttcgagg
     5401 attttttgaa tgttttcttc cgataattta ttctgatttt ttcctttgac aaattctcga
     5461 ctagcgtcaa tgaataatac gtctcgagtt tggcggttct ttttcaatac aatcaccgtc
     5521 gttggaatcg atgtcccgaa gaacaagttc gcaggcatac cgatcacagc ataaatactg
     5581 ccgtcttcta gtaatttttg acgaatgacc ccttctgcag cgccacggaa taaaactccg
     5641 tgtggcaaga cgatggccat agtccctgtt tccttcaaat gatagaaacc atgaagaaga
     5701 aacgcaaaat ctgctttgga ttttggcgct aattttccat aacgattaaa ccgagaatcg
     5761 tctaagaagg tcgtatctgc tgaccaatta gccgaataag gtgggttcat tactactgca
     5821 tcaaatgtgt aaggttcatc tgttggccaa tccttattca acgtatcccc attgcggaga
     5881 ttcatttctt cggcatctac cccatgtaaa atcaagttca tttttgctag attgtatgtc
     5941 gttgtattta attcttgccc atgatattta acgttatctg ggtgagttaa gtagttacgc
     6001 acatttaaca tcaatgaacc tgaacccatg gttggatcaa aaacactaaa gaatcgtcgt
     6061 tctttttgat ccaacgtcac gatttgtgcc atcatatcag aaaccatatg aggcgtgtaa
     6121 aattctccgg ctttcttccc tgcttctgaa gcaaattgac tgatcagaaa ttcataagca
     6181 tccccgatca cgtccccatc gtgacctaaa acttccacgt cattcaattt cttaatgact
     6241 tcggtaatcg tcacatttcg ttgttgctca tctgttccta gtttttttga ttggagatcc
     6301 acatcatcaa ataacccatt aaattgattg taggtagatg ccaattgcac aaaggctttg
     6361 tttagatcat tcaattggaa cgttgcttgt tttgcttgat ccgctaagac gttgaaaaga
     6421 tactctggcg aaatcgcata ccccaaaata tcaacgattg ttgcaatcag atcttctttt
     6481 gattcttcat ctgaaagtaa ttcgcgatac aacatcgttt gtttgcttac cgtatcatat
     6541 tcctctaagg attcatctgc taaaagaacc acttgttcca acaaacggtc ggataaatat
     6601 ttatagaaaa tcagtcccaa taaataattt ttatattctg acgcatccat tttgctacgg
     6661 agattatctg ccgcactaaa taatttttga tttaattctg cacccaaaaa gatacactcc
     6721 tatctcttat ttaaagttgc tatataccct cttattttag catactccct tttagaaaaa
     6781 gcaaaaaaaa aagaaagaaa cttattcttg ctaataaact acgcgaaagg agtctaacgt
     6841 tgtttgatat aacttagact gatcgttaac ttatttttta tatttctaca tagttatctt
     6901 tagaaccatt tcagatacat atgaaacaat tacatatgat tttttcataa aaaaacagta
     6961 ctgtctagta gtataaaata tacaaatttc ttaaaaattt tttcactaaa atcactacct
     7021 gaaacagtct aaaacactta tatatcaacg tttaatgaaa ctatctccgt ttcatttcag
     7081 atacaaataa atatagtcgg gctccaaatc cgaaaaaaaa tacccccagt agcttatcct
     7141 aagctactgg agatgtataa gtacggtcat ataacaacgg ggtagggtaa ataaatgaaa
     7201 aagatggaag aatcattatt caataacttt tttaaatact tcgttgtaat cagttacctg
     7261 tccgttctta aataccacag aataatcttt tttcccattt tcaagtaacc gaagtggaat
     7321 atctttacca actttctctg tcactgcatt actgatacct gttagattag ctaataaatc
     7381 tgataaagat tgagcatctg tagaaatctc tgtatcagta tttatcgtga ttcctttatc
     7441 ttcatttaca agtttccaag taggtggtat agctgtgtat gtttctacaa atgaattaag
     7501 tttttcatta agtgacttct cttttatatt tccatctaaa aactctgtat atatggcttg
     7561 agctatacta aaacaaagct ggccttgttc taataatttt acatcattag ttagtaaagc
     7621 tgtgttcacg ttatcaatcg cttcaagaag agtatctttg gtgtccctaa cagctttagg
     7681 tgtgccttct ggaatttccc tacttgatac ctcgtccatt ttatcttcca taaacccctt
     7741 aaaatcatat ctttctccca aatccataga agtttttgag aaagctttca tttctgagtc
     7801 tatttcttca ataatattta acatgtctga tacatattgt ttaggctgat tcgtttttaa
     7861 tctatatgtg gtaaatatct caattcctcc aattatcaat aaaattgcca aacaaatcca
     7921 taataatttt ttctttttca tttttcctcc tatacactgc tgttataaca gtgactaatg
     7981 taaagatttt cccagcaatc atcagactat tatttacagg gaatcaaaaa aactccttag
     8041 taagcttaca cctttaggag ttcctgtttg aacggtatgc ataatacatt taaatcaatt
     8101 taacattaac acctcagtat atggtatctc tacatataca cggtcttttt ttggatagta
     8161 ctcgacattt atattgatag cacttccatt gtctaacgta gctttagccc ggtacgtgtt
     8221 atcaccatta tcatgagtga tcgtcacatc atcacatgtc cgatttaagt tatactgttc
     8281 ttgtaaaatc tgagttacca atggtacaga tgacttctct agtccagatg aacccgtcat
     8341 tcttgaaaaa attataccta taatagccaa tacaacgata cctataatga caaacttctt
     8401 attcatattt actttattca actttttatc tcctatctcc aaaatgattt tctctcatca
     8461 gtaactcatt gacatcccca atagtacacc aaagatggct ccagctaccc ctgctatcat
     8521 caaaatcgta cccatttgtt catctttctc tcgatataag taacccataa taacagcaac
     8581 agcaccaaat accacaggaa taaatgctaa tgatactacc atagaaatcc aaccaataat
     8641 caaatacagc ttccctgtct cttgtccatg tacgatttgt tccttcattt cattaattgt
     8701 ctgctcagta cttttcttta ctgtgtctgt tccggttgtc tcatctgttt cttgtaatgc
     8761 tccgcaaaac tggcaatact tactttcatt tgttatttct ttaccacatt ttctacaata
     8821 catgtcttct cctcctaaaa tcattcaatt gcttattagc taactgttta ctttattaaa
     8881 tacatcagaa aacagctcat ttattggtac acttaatatc tcagaaagca ttttcatttg
     8941 atagggttta ggaatcgttc tccctgtttg ccacgaactt acacattgct gtgtaacatt
     9001 catttttttg gctaactcag tttgggaaag tcctttttct tttctgtatc ggctgagatt
     9061 acttactttt ttcatgattc tcccctcctg ttttattata tacaacaata tgatgtattt
     9121 caactcataa aatatataaa tacttcaaat gtcattacaa atacaacaac ttgttgtact
     9181 ctactgagaa ggggggtgta ttaatgaaac agaagcaata tgcaaaggtc attagagaaa
     9241 agcgaaaagc actcgggtgg acacaaaaag aattagctaa aaaaatcttc tctacacaac
     9301 aggcagtagc aagatgggaa aattctgtaa cagaacctaa cctcgatagc ttaacagctc
     9361 tttctagagc cctaggaacc cctgtaagcc attttctaga caatgttgac atagattatg
     9421 aggaagagtt tttggctctc tatcgctctc ttagtactga agatgcaatt cgaacaattg
     9481 actatatgaa gctattaaaa aggcaagaaa atgaacgcaa tcagctattg aaagattgaa
     9541 aaataaataa cccaccgaac tttaacggtg ggtgtattga gatgaaataa gattaagagc
     9601 tatggataac ctgtctagtt taatataatt gggtctcttc tattccttac tctccgtcca
     9661 tcatctcttg ttacacttgt aaattgataa ataggaacta attcaactcc tgataatatc
     9721 aattctttta ttacttcatc tatccctgcc cctttcgcta gatatactaa aaaactactg
     9781 cttgctttca cattgtatag tttcttaata tccttagaag ctcgttcaag agtgaatcct
     9841 tgtttaacaa agtagcctct gttttctatt aaagcatttt tcacgctgtt atccctgaca
     9901 tttcgtaggc gttcacaaac agtgttaata agttcttttt ctgtcattag atatgtccct
     9961 tgccacgata agccctgtaa aacttcatgt gcttcatcta aaatcaattg tttttccttg
    10021 ctaagttctg atcgggaatt ttgaggaaat actcttttag cctctttttc gttaaaacat
    10081 atcttaaccc attcataaga aaaatattga tatgtaaaat gaaatttttc cagaagtgga
    10141 aggatatctt cattcaattt ttgaatcaca gaagttgcat taaaaacgtc taatcgatag
    10201 acattgcttc tcttatgttt aaagtttcct aacgctttct cttcctttaa cctatttagg
    10261 tattcgagca tcttcaaagg aacatcttca tcatctaatt tttttatcaa tcctataaaa
    10321 gtcataagtg atagtaactt attacattta tctatgtcat aagttttacc atagtaagaa
    10381 ctcatttttt tagctaattg ttcccccgac aaaatacaag tcacactttc cttactatca
    10441 tcaaaaaaat taacatcaga aagcaagaca tcatagacac gtcgcatttc ctctagataa
    10501 ttccttattg tcctgaaaag tttgtctttc attgattcaa gagtgtcaaa aagtactttt
    10561 gattcctctt tcaattttcg aaaatgtgta ggatacaagt ctaggttctc taatagccaa
    10621 ttaaatgttt ctacccgact gtctttcttt aaaattagca tcacaactcc aataaaattt
    10681 tcactgatat cacaattact ggaatgacaa taaaaaatgg aatgcccagt tttactggta
    10741 aaaatactag cagagggatt atgatcgttg tgaaacagac atcttaagtt tttacttgac
    10801 ttaagtaatt tattcatatc aatggttaac aatctttcat aaatctcatt aaaagacatg
    10861 tcggaggaat caaacaggca gtctttaaac cactgtttca tttcttcttt gtcgtcattt
    10921 tttatcaact taacaaaatc ggtttcattg actagttcat actctctccc tgaatcactt
    10981 tgacaatttt tagaacatgt catggtaaaa tcaatcggaa gctcagtaat atctaacatg
    11041 ttgtcttcat taattattat cactgcatct gacttatatc ctccaaaaaa cattctattc
    11101 gaagcattta cattgtcatc acacccgggg atgttctttt tcaagtattc gtaaacagca
    11161 accattttac catagtcagt aattgcttct tttaatagaa agacaatctt gtatttttct
    11221 agattttcag agtaccgaat acttttttgt atcgcaaacg cagaattatg aactaaattg
    11281 atagataaaa ccttttctat gcttaagtat ctactatcat ctttactcaa atctactacc
    11341 ttccccttct catctttaac agtgttatcg acatccagaa taattactct ggtttccaca
    11401 aaactctcct tgtcattgcc tttattcttt gtcttgcttg gaataaatga ttgtgatgaa
    11461 tttagtatct ctacaaactc atctcttgta acttctctat agttatctaa acacctatct
    11521 cttacatcag ttttttcttt ttttgtaact ggcttctcta ataatttttc ttgatctaca
    11581 taaattggaa tattaatcat tgatgtttcc atttgtgttt cctccttata aaattctgtt
    11641 aaagactaaa acatacagat aataaaaaca aactctttat tactatatgt tttagtctta
    11701 tttgtttact caacctttat accgttccat gaaactatca atatcagatt ttttaaatct
    11761 aatgaccgta tcaattttta taacaggtaa cccgtattga gaaacatatt ttctaatcgt
    11821 tcctactgat acacctagat attcacttgc ctgctgatag tccatatact ctagagtgac
    11881 tccagaaata atgtcttcta gcataggctt tagcactgta attatctctt tcacttgttg
    11941 ttcaacttgt atagaaacaa tgctatcaat gatttgtaga gacatatttc cccctccttt
    12001 cgtgattgct tgaacaaatt ttctaagaat tatcttcgta ttttttgctc aaaataaaag
    12061 tattttgtta ttaaccgatt aatcaaacaa aaaatgatta ccagttcatc gacatacaca
    12121 taatacctcg ataaaaaagg ggtgtcaaca gctttgtaaa atttatttac aacacccctt
    12181 ttttgaggta tactaatttt aggaggtgtg gtcaatatga taaaacgtcc accaataaat
    12241 tatttagaac gaaaaaagat actcggaaca aaaataaaag ctataagaaa gagtaaaaaa
    12301 ttaacacaac cagcatttgg tcttatgatt aacaacggtc aattaattga caaaaaaact
    12361 atctacgaat gggagaaggg aacctattta ccaataccag agcgattatc ccgaattgct
    12421 gatttgggaa atatgagtat agaggagtta gtttgtggca atgtagaaga atatattttg
    12481 ggaattattc tttatagaga tagcattgta ctagatggta taacatttcc agataaaaac
    12541 ctgttccagc atcttcgtca acagttccca ccagtacact ctaatttaga tacatggctg
    12601 gatagatatt ccaaattaga accagagatg caagaattta ttgctaacaa gacttgtaat
    12661 aaagttaaaa atgaaaaaat tagtcttttc aatatcttaa aaatagaaga attattcatc
    12721 aatgctattg tagaagaatt tgacaataac attcttttcc tcactagcag tatagaagaa
    12781 ctactagaaa gaatggtaga tgaatggcta cctattcaat tgaaagacat gtcttatccc
    12841 gaagaagctg tgagagaaat tactgataat ataaacaagc tagaacaaac gatttcatca
    12901 attgggaaaa aatacactaa gaaaaaaatg aagggaggtg ataccatcta gtggtaagta
    12961 ctccttgtaa actaagagga gatgatttaa tggcaaaaat atcaaagtac aaaaagaaaa
    13021 acggtcaagt ggcgtggatg tataaaggac acattgccac cgatccacga actggtgaaa
    13081 aaataaatac tacgagaaga ggttttagta gcaaacaaga agctcaaaaa gattatgacg
    13141 agtacagaca tcaaatatta tacggtgtta aaaagaaagc acctgatatg acatttgaag
    13201 acctgtataa tgaatggata actcatcagc gtaccagtgt taaagcttca acaatcgcaa
    13261 tctcagtaag atacgcaaat aatcaaatac ttccagcatt tggtaagctt aaactatcga
    13321 atatctctgt cccatattgt caaaaagtgg tagatgaatg gcacagtaaa tatgaaagtt
    13381 acgattatat gagaaaacag actgcacaaa ttttacgcta cggggttgca atgcaatata
    13441 ttgacaataa tcctatggaa aaaacacttc ttccacgaaa aaaagagtat gagaaaaatc
    13501 gtaaatttta ctcaaaagag gagcttaata atttactgga tgcttttaaa gattttggta
    13561 acatgaaaca atacgccttc ttcagattat tggcatacac aggtatgaga aagagtgaag
    13621 tactcgcttt acagtggaaa gacatagaca cgtttaataa agaactacat gtcaataaaa
    13681 ctcttgctgt agatgaattt ggtaaagtta taattcaatc tccgaaaaca agagcttcta
    13741 gacgagttat ctctttagat actgagactc tttctatcct caacaactgg aaattacagc
    13801 aaaaagaaga gtatttaaaa cttggataca atactagctc taaagagcaa catgttttta
    13861 caacagttaa aaacactcta tacattccaa acactgttaa tgattggtta agatatattt
    13921 tgaaaaaata taacttgcct cgtattacac ctcatgggtt tagacataca catgctagtt
    13981 tattattaga agcaggagaa tctgtcaagg tagttcaaca acgattaggg catgaaaata
    14041 gtaaagtgac attagacatc tatgcacata ttacaaataa tgcacctaag aaaacaggtc
    14101 aagactttgc tgatatgatg gctcatcagt aaaagagctg gtcaaaatct ggtcatttct
    14161 agtatacagg caaaacaaaa aagctagaac ccttatatat caagggttct agctcctata
    14221 acaggtttac ccaacactgc cttccatctc ataactgatc aatcgattga gttcgactgc
    14281 atattccatt ggaagttctt tggtgaatgg ttcaacaaag cccatgacga tcatttcagt
    14341 tgcttcagat tcggtcaggc ctcggctcat cagatagtag agttgttctt ctgagatttt
    14401 tgagactttg gcttcgtgtt ctaaagagac ttggctgttg tggatctcat tgaatgggat
    14461 cgtatcggat ttcgaccatt cgtccatgat gatcgtgtca cattcgatat gagagatcga
    14521 acccgcactg tttttggcaa aggttacttg tcctcgatag tttacttctc cgccgtcttt
    14581 tgaaattgat ttagagacga tagagctaga tgtatttggt gcattgtgga tcatttttgc
    14641 acccgtatct tggatttggt ttgctcctgc aaaggcgatg gagagcatgg tgcctcgtgc
    14701 accttttcca tctaagtaaa cacttgggta tttcatcgtt gtttttgcac ctaggtttcc
    14761 gtcgatccat tcaacggttg cgccttcgta tgcttttgct cgtttggtta ctaagttgta
    14821 cacattgtct gaccagtttt ggatcgttgt gtaacggcaa tacgcatctt ttcttgtaaa
    14881 gatttctacg atggcggcat gcaggctgtt acttgaataa gtaggtgccg tacaaccttc
    14941 gacatagtgg atgcttgctc cttcgtcaac aatgatcagc gtacgttcga attgccccgt
    15001 gttttccgca ttgatccgga agtacgtttg taatggaaca tcgactttga cgccttttgg
    15061 cacgtaaata aaggtcccac ctgaccatac ggctgaattc agcgctgcta atttgttgtc
    15121 ggttggcggt acaagttttg aaaagtactc tttgaataat tcagggtatt ctttcaaagc
    15181 agagtcagtg tcagtaaaga cgattcctaa cttttcgaat tcatctttca tattatggta
    15241 cacgacttct gattcatatt gtgcggaagc accggctaga taagctcgtt cagcttctgg
    15301 tataccaatc ttttcaaatg tatctttgat tttttctggt acgtcttccc agtcacgagc
    15361 gggtttgtca cttggttttt ggtaatattt gatggcatcg aaatcgatgt ctgaaaggtc
    15421 ggggccccat gtttgcattg gcattttgtt aaatgtttct agagatttca gacggaattc
    15481 aagcatccat tctggttcgc ctttgattct tgacatctca cggatcactt cttctgtcaa
    15541 gccttctcct gtactgaaaa ccggttcgac atcatcgtga aacccgaatt tatattcttc
    15601 taattctggt acgcccatgt tctcactcct cttccttgtg gtaatgatgg aaagctgcgg
    15661 taccatcgtt ttccattgct tttcctagtg ctttccaggc aagtgtcgca catttgatcc
    15721 gagcgggaaa tttagctaca ccaccaagca tagcagcatc gcctaattgg tcgggatctt
    15781 tgacttcttt tccttggaca agctgtagaa agtctacagt taaatgttct gcttcttcta
    15841 ttgattttcc gatgacggcg tctgtcatca tcgaggcact tgccgtactg atggagcagc
    15901 cactgccgtc aaaggcgata tttttgatga ttccgtcttt tacatcgact tgcaattcga
    15961 tcacatctcc acatgtgggg ttgttcaatt cgatcttgct tgtcgagtca gtcaagcttc
    16021 cacgatgatg cggatgggaa gaatgatcca agatcacttg acggtataaa ttgtctaatt
    16081 tagatagtcc catgttggaa aaactccttt gttgccatga ttgcttcaac taaacggtcg
    16141 gcgtcttgcg ttgtgttgta gaaataaaag ctcgcgcgag cagtcgctga tacttcaagg
    16201 tacttcaata gcggttgcgc acaatgatga cctgctctga cggctacccc ttccatgtct
    16261 aaagctgtcg cgacatcatg gggatgtaac ccatccaaat tgaatgcaac gactcctgtc
    16321 cgaaaattcg ggtcttgtgg accataaaca gtcaatccat caattgcttg taattttggc
    16381 aacacataag cggctagttc ttcttcatat cgatggatat tgtccatacc gagtttttgc
    16441 aaataatcga ttgcatggcc taatgcgata gcgccggcga tatttggtgt ccctgcttcg
    16501 aatttccaag gtagttcttt ccatgtactg tcgtataatt cgacaaaatc gatcatttcg
    16561 ccaccaaatt caacaggttc catttcttct aaccattttc gtttaccata taaaacacca
    16621 atacctgttg gtccgcacat tttgtgtccg ctgaaagcaa agaaatcaca gtctagtgct
    16681 tggacatcaa tggccatgtg cggggcagat tgagcaccat ctactacgat gaccccgccg
    16741 ttttcatgga caagttcagc taattcttga acaggattga agacacctaa gacattggat
    16801 acatgagcaa tggagacgat tttggttttg tccgtaatct ttttcgctgc atcctccata
    16861 tccaggaagc cttcttctgt tagttcgata tatttcaaga cagcacctgt tcgttttgcc
    16921 aactgctgcc acgggataac attagaatga tgttccatgt aagagagcac tatctcgtct
    16981 cctgctttga tatagcggtc gccgaaggtt ctggctaccc aattcaagct tgtcgtcgta
    17041 ccacgagtaa acagcacttc tgctgtttct tttgcatgga tgaacgcccg tactttttct
    17101 cttgcttgtt cataatcatg ggtcgcgcgt tctgctaacg tatggacacc gcgatgaaca
    17161 ttggcgttat cgtgttcgta atagtacgct aatgcctgga gtacttgttt tggcttttgg
    17221 gtcgtcgctg cattatccag ataaactaaa ggttcatcat tgacgtcttg aaataagata
    17281 ggaaaatcat tgcgtagctt tttagcatcg atcatccatt caacttccct tcgattactt
    17341 cgactaattc tttccgaact tgttctacag ggattgctgt taagacagaa ccgaggaatc
    17401 ctcgaatcac taagcgctct gcttcttctt tatgcaatcc tctactcatc agatagtaca
    17461 tttcttctgg atcaactcgt cctacactgg cagcatgtcc agcagttact tcgttttcat
    17521 cgatcaaaag aataggattc gcatcaccac gtgctttatc agaaagcatc aagacacgac
    17581 tttcttgttg ggcatctgca ccttttgccc ctttcaagat gtggccgata ccattaaagg
    17641 tcaatgttcc tttttctcgg atcactccgt gttgcaaaat atgcccgatc gtatgagggg
    17701 ctttattggt tactcgtgta tcgattcctt ggatttgtct gcccgagctg attgccacga
    17761 ttttgacttc tgcgtgtgca ccttctcctg ctaaatctga gtcaaagtca gcgatcacat
    17821 gaccgtcatt catgacacca attgcccagt cgacagaagc atctcgtaaa atgtgcccac
    17881 ggcgattcat ataagaagta atattttctc ctaattgatc tacggctgaa tatttgattt
    17941 ttgaaccagc tttagcgatg acttccacga tgatattacc tgatgatttt gctacttgtt
    18001 ctttggttgt ctggaaacgt tccagataag aaaattcact atgttcatct gccacgatca
    18061 acacatgctt gaagaagtgc tcatcggatg cgccatcttg aatgaataag gactcgagtg
    18121 gttcatcgat cacgacattt ttaggcacat acaggaaaat accgctgttc ataaaagcta
    18181 catggagtgc agtcaattgg tcttcgttca tgtttactgc ttttttcata taatattctt
    18241 ggactagttc tggatattcg atcattgcag tgaacaagtc ggtaaaaatg actccttttt
    18301 ctgctaattc cacaggcagt tgttcaaaaa tcgtccatga accttgttgg acaagcacag
    18361 gattgtcttt cattgcatca aatgccggaa tcgtgcctgt ttcactgatg gtttgtgttt
    18421 ctttcacatc aaataacgac cagcgatgga atttcacccg atcgatatgc ggcaatggca
    18481 gttcatctgc tttcgctagt gcgtcttgac ggaaggttct catccaatca ggttcgcctt
    18541 tacttaaaga aaaatcattt accgcgtcaa gataatcgag ccagtttttt tctttcattc
    18601 ttgctccccc ttacgcttct tcttctttat agtcgattcc taattcttta ctgataccag
    18661 cgtagccttc tgcttccaga cgtttagcta ggtcagcatt ccctgtcatg actactcggc
    18721 cttccatcat gatgtgaacg acatcaggtg tgatatagtt caataatcgt tgatagtggg
    18781 tgatgatcaa tgcaccgaaa ttgtctccgc gcatttcatt tactccttta gcaacgactt
    18841 tcaaagcatc gatatccaga cctgaatcga tttcgtctaa aattgcaaat gtaggttcta
    18901 acatcaacaa ttgcaggatc tcattccgtt tcttttctcc gccagaaaaa ccttcgttca
    18961 gataacgttc agccatttct tctggcatat ttagtaaagc cattttttca tctaactttt
    19021 tcaaaaatgc cataacagaa attttgtcgt tttcatcacg tttcgcattg atcgctgcac
    19081 gcatgaattc cgcattcgtg atacctggta tctcacttgg atattgcata gctaaaaata
    19141 agccaagtcg cgcacgttca tctacttcca agtctaaaac atttttcccg tcaaacaaaa
    19201 tttcgccttc tgttacttca tagtttggat tgcccatgat agcggcagat aaggtagatt
    19261 ttcctgtgcc gttaggtccc atgatggcat ggatttctcc ggttttcatt gttaggttta
    19321 cgcctttaag gatttctttt tcctcgatcg acacatgtag attttttatt tctaagacag
    19381 acatgcatta tacccccaaa ttctctttcg ttctcactca ttttagacta attgagaatg
    19441 aagcgcaatg accttcctta ctaaaatcaa atatctttta tttattatta aacaattttg
    19501 atttctaaat tagaataggt ataaaaaaga tgagaaataa gccattacag acttatttct
    19561 catctttttt gttccatacc ttattttgca tcagccttta ctggtttaac agagccgccc
    19621 catttgtctg tgatccattc ttggacttct ttgcggtgaa gcacttcaat cagttttttg
    19681 attttgtcac tgtcttcatc acctttacga gtcgcaataa tattcacgta aggagagttg
    19741 tccttttcaa gcaatacggc atcttctaat ggattcaacc ctgcgccgta agcgaagttt
    19801 gcgttgattg caactaggtc accttcatca ttttggtacg tagaagctaa aagtgatggg
    19861 tcgatcgtat ggttgaactt caagttctta gggttttctt caatatcatc gaatgttgct
    19921 gtttccagat ctactccatc tttgactttg actaagccag catcttgtag aattgtgatg
    19981 atgcgtcccc agtctgattc agaatttgaa gtaatgattg ttgcaccatc ttttaattcg
    20041 gaaacatctt tgactttttt agagtacaag cccattggtt cgatgtggac agcaccggca
    20101 ttgacaaagt catatccttt ttctttgatt tctttgttca aataaggaat atgctggaag
    20161 taattggcat caatgtcgcc ttcttccaaa gattggttcg gtaatacata gtcatcgaat
    20221 ttgacgattt caagatcgat tccttcatct ttcaataatg gtttcacatg ttccaaaatc
    20281 tctgcgtgcg gtgtcggtga agcgccgact ttcaatgtcg tgtcgtctgc tttatttgct
    20341 gaatctttgc tgtcgctgtt gttaccgcat gctgctaatc ctacagtcag caaaagcgct
    20401 gctgcaaatc caaaaatttt ctttttcata tcctacatcc ccctatatcc tattatcttt
    20461 tgtctgtttt cttagttaag aaatcaccga ttccttgaac gataaatacg attagtaaaa
    20521 taattaaagt cgcaacgaat gtcactgtta gattaccacg ctggtagcct tcctgccaag
    20581 caagacctcc aagtccacct gcgccgatcg cgccggccat cgcagtaaat ccgatcatcg
    20641 agatcgttgt aactgttaat ccagaaatca atgcgggaat actttcaggt atcaagacct
    20701 tccagatgat ttcccagtaa cttgctccca ttgcatctgc tgcttccagt acaccagggc
    20761 tgacttcacg aaaagcaatc tctactagac gggcataaaa tggtgctgcg gataaaacaa
    20821 gagctggaat ggctgcttgc gcacctagca tagtgcctac gattgcttta gtaaatggaa
    20881 tgatcaaaac catcaggatc ataaatggcg ttgaccggaa aatattactg atgatcgata
    20941 cgattccata aatgattcga gcatacggtt tgtttttgcg tccaatagag taaaggatca
    21001 atcccaaaac taatccgatg atcgtcacta agaccattga gattaatgtc atatatagtg
    21061 tatcaaggat agcctgattc atcgtttccg ggttgatttg tttaaaatct agatatgttt
    21121 ctgaaaagct tttatccacg atggatcacc tcaattccta ctccttgttc tttgatgaac
    21181 acttctgctt gatctaattc tttggtttca ccagtcatca agacagtcaa tgaaccaaag
    21241 gaaccttctt tcacttgttt gatctttcca tacacaacgt tgacatcgat gttatagcgt
    21301 cgaatcgctt gggaaatgac tggctcgttg gcatttcttt cgctaaaggt caaagttgcc
    21361 aaacggccgc ttggattttc tttgatgagt tcagctaata gttctgtcga atcagcttct
    21421 ggttcgatgt cttgttgtac aaagcgtttg gttacttctt ttttcggttg tctgaagaca
    21481 gtcaatacgt ctccttcttc tacgactttc cccaactcca tcacagcgac tttgttgcag
    21541 attttgcgga tcacattcat ttcatgtgtg atcaagacga tggtcaaatt caatttctta
    21601 ttgatcgcta acaataagtc taatacttct tctgttgttt gcgggtccaa tgcgctagta
    21661 gcctcatcac aaagcaggat ctcaggatca tttgccaatg ctcgtgcgat accgacgcgt
    21721 tgtttctgtc cgccggaaag ttgtgaagga tatgcttgtc cgcgtccttc taacccgact
    21781 aaacgcaaca gttcttctgc ccgttcttta cgtttgctct ttggtacgcc agctaattcc
    21841 agcggcagct ggatattttc aagtacagtt cttgaccata acaggttgaa atgctggaag
    21901 atcataccga ttttctttcg gaatgtacgt aattctttgt tttttaattt tgtaatatct
    21961 tgatcgttta cgatcacttc gccgctcgtg ggaagctcaa gtccattcag gagacggact
    22021 aatgtacttt ttcctgcgcc agaatagccg acgattccat aaatatcccc tttttcaacg
    22081 tttagtgaaa cgtcattgac ggcttggatg tttccgtttt tcccattgaa tgtctttttg
    22141 acattcgtta gttggattaa tgacatgcca ttcacatctt tctcttatga tttttcaaac
    22201 aaaaaagcct tcgccctctt gccttaagca aaaggacgaa agcttgaact tccgtgttac
    22261 caccttgatt taccgttact tcgcaataac agcctcttcc agtacttgga cttagcttct
    22321 ttccgtatac tgtcgcgctg taacgggcac tcccgtagta agtttgctta cgctcgctta
    22381 ctctgctcta agaccatctt ccatctcatt ttcgttaccc attttcagca aacagggctc
    22441 tcttcaaacg tccgtgacat gtactcttct tttcaaagct ttctcgtttc atataggatt
    22501 gcttatgatt atagcaactg gaagaatcag tgtcaacttt tttcaagtga ttttctgatt
    22561 ttataattcg tcaaattctt ttggatcaac atctttgaaa cttaagatcc acgcattcat
    22621 ttcatctgaa tcattcaaga tattgatatc ttcaccgatt ttatcattaa cagaagaaac
    22681 tgtacccgtt agcgggctgg caaattcatt gaccgctttt tccgcttcaa cttcgatcag
    22741 aggttcatct ttttttagcg attgtcctgc ttttggcaga ttggcaaacg tgatgtctcc
    22801 aagttcttct tgcgcttcat ttgtcaaacc aacacagtat tcttttccat taaataagat
    22861 ccaaaggttg tcctttttct tcaaatgctt gcctgccatt ttatatcagt tctccttcat
    22921 aaattttttc attgaatcca attgcaacaa gctggtcctc tcgtaagatc agtggtcgct
    22981 tgatcagcat accatctgtc gataagactt ggctcgcttt tgaagccgta aactcgccta
    23041 cttgatcttt cagtccaagt tcccgatatt tcatcccgct tgtgttgaac aggcgacgga
    23101 ttggtacttg actcgtttct agccaagtct caatcgttga ggccttcggt acttctttga
    23161 tcatatcaac ggtttgataa ctaacgccat gctggtctaa ccacgctttg gcttttttgc
    23221 atgttgaaca tttcgggtac cagtaaaagg tgtacaattt tcttacctcc ttgaagatct
    23281 tgcaggtgct tcattttggt atctcatcga taatatcaac ccgataccga tcatgttccc
    23341 taaaatcgag gatcctccct gactaatgaa aggcaatggg atccctgtta aaggaagtaa
    23401 tccgatattt gctccaatat tctcaaagac atggaacagc agcatcatga tcaaaccgct
    23461 tgcgatatag gcgtaaaatt cattattcgt atcgaaacac acccgaatca tacgatagat
    23521 taaaataaaa tacaagaaaa tgacgaatgc accaccgata aagccgaagt tttcaccgat
    23581 aacggtaaaa atcatatcgg actcacgaac aggcacatag atattgctta cgttgaatcc
    23641 tttaccaaac aagccaccgg taccaattgc caaaagtcct tgggccggct gataactcat
    23701 tcctgacgta tcatggaaag ggtccagcca tgaatcaata cgtgcaaact gataagattt
    23761 gaatccaact ttataaagca agtctcttcc gccttcagtc gtaaccaaga agatcgttcc
    23821 tgctccaacg actactgcca agattactac aggtgcgatg atgcgccaag agattccaga
    23881 catcaggaaa atcccgccaa agatcgcaag aaagacaagc atcgttccaa agtcatcttg
    23941 ggccatgatc aatgctaaaa ccggtattgt cacgatcaag agcttcccaa tcagccaaaa
    24001 gtccgatttc atcgtccgtt cttttacttg cgtattatgt ttagttacga tcagtgccat
    24061 catcaagatg tacgcaatct tcatcaactc tgctggctgg aaagtaaacg caccgaatcg
    24121 aaaccagttt ttagaccctg ttgaagcagc taaattctga tcatagaatt tgagcaagag
    24181 tcccattacc actaacccca aaccataaag gtaaggagtc agtttccaga tccatttgga
    24241 attcaaatgc atgatgacaa cgattgctgc cgctccaact aaataccaga caacttgcat
    24301 ccctacgcct ttcaagactg ctggattgtt cggatcatgg ctaagtgcta catataatga
    24361 gagcagacca atcaaacata acagaaagac tggtaaaatc acgccataat caatacgatt
    24421 atcgttcgaa gcttttaatt ttttttccat gtttcatccc ttttcttaaa aaccatactg
    24481 ctgattatta tagcggtcca gttagataat ggaaagtctt tccatagaca tttgggaaaa
    24541 attaactttc cgtttgtgca gttgcttgag caaatgcagt acaaaagcct actgcttatc
    24601 tttagtgtat catagaactt tttttgatac atgcaattat ctaccagctg agattctcct
    24661 cgctgtgaga agtttctgtg ctttcattgt atcgaaggat ctcttcggca atctctagca
    24721 gctgatcaga aaccagattg gttcgttgga tgaaataaaa atatcgatgg aaattcaacg
    24781 gagtcattgg cacattttct ggaacagagc gcttagacaa aatcgagcga ccgattcctt
    24841 ccttcagcaa cgcaacaatt acatcgttac ttttcacgat catcttctta tcttggatat
    24901 tcatctcttc aaaataacgc tgcgtgtaat gaaaaacacc agagtttgct tctcttacaa
    24961 gccacaattt gctttttggg tccccagcga tgactagctg gtcttccatc aaagagtatc
    25021 tttgtacgcc ggaagtctct aatggctttt cgataaaacc aaaatcggat tcatgtttcg
    25081 ctacttgttc taatgattca tgagaattcg tgatttcgat ctcaaaatgc actttaggaa
    25141 accttttgat cagatgtttc atcaactgag gcaaaagata gacagcaaag gtgtgggaag
    25201 caacgatccg acatacttct tcttcatttt gttcattgag caatttttgc tgagtttctt
    25261 cccattcttc taacaaaacc agtgtccgtt catataataa gtcggcttgc ttagttggaa
    25321 gcatctcttt tcttccgtta cgttgaaaaa gatcgatatt caattcccgc tccaactgtt
    25381 tgatttgatt cgagactgct ggttgagata aaaacagtac ttctgctgct ctggaaaaat
    25441 ttcttgtttc atatactgct cgaaaagtcg ttaataactt aaacatggca ccacttccat
    25501 aactttttat gataattact ataaaaacta tttgatttaa atatacaaaa aaccatctat
    25561 aatagaaatg tacaacaaaa cagttgctga tccaactagt aacttagatg aagacaatca
    25621 gctgtctgct tgctcgtaat catacattcc tattcatttt acaatgtatt cgttcatctt
    25681 ggtactaaaa tctattaaat aaaaaggaga atattatata tgaagaactt tttgaaaatt
    25741 attccgatcc cgatctgcgg gttgatcctt gggttagctt cccttggaaa tctgtttaaa
    25801 gactatcacc atgttgcttt aggcaatcta actggcggta tctctatgat tcttatgata
    25861 ttcatttttg ttaaattgtt tatcttattc gaacacacga aacaaacgtt gcatgatcca
    25921 atcatcgcct ccgtttcacc aacttttacg atgtcactca tggttatttg tacttatttt
    25981 gtttcatatg aaagtattgc accaattgtc aaattcattt ggctgtgcgc tgttatcttc
    26041 caagtgatcc ttgtctttta tttcaattat caccatgtta tcaaagctga tctttcaatt
    26101 gaagcaattt atccaagctg gtttatcatt tacgttggat ttggggtcat cactgtaact
    26161 gccgggaact tcttcccact tattggaaaa attttctttt ggatttcatt gatctgctat
    26221 gcgttcttat tgccgatcat catcaaacgt gtctttttcg taagaaatat ggctcatccg
    26281 acacgtccgc tgattacgat cgttgcagca cctggttctc tttgcctaac aggttatctt
    26341 aaaaactttg ctgaacctaa tttttatctt gtcgtagcat tgttcgcttt atctcaagta
    26401 ttgtatttcg ttgtgctgtc tatgcttcca cgtttgttca agcttcgttt ttatccaagc
    26461 tatgcagcct ttacattccc gcttgttatc tctgcaacag ctatatttac tactgttcat
    26521 tacttcaaca gtttaggtat ctatagtagc gtattggatt tcttaaaagt tgcggaatgt
    26581 ctgtttgcaa gtgtagttgt cttctacgtt cttgctcatt acgtacgttt cttaattaaa
    26641 gaacatagca aacatggaaa atttgtttct aaaaaaatcg cttaataatc gattcaatag
    26701 gttgtgaaaa agctgttctg catcaagtaa taagaacggc caaacaaaaa cagctgttca
    26761 tgtttttgta ctggttgggc ttattaccgc agatgcaagc ttttgaacac cgtttaccaa
    26821 gaggtcgtaa aagaagtggt cagcttcaag aaataagaag gaatttacga aaattgcttc
    26881 tcaaattttt gtgaaatttc ggcttatttc cgtagaagct acttctggaa caccgtttat
    26941 tcgaaacaag aggtcgtaca agacttttgt cacgacctct tgttcttttg tcaaaatact
    27001 ggtttagtgc tactatgttc gagtatgctt ttagtattta ttgacgaaag gaaccgatca
    27061 aatgaaatca ttgtcacatc caataaaatc tgtaaaggat tcagcggtcc gcgaaatctt
    27121 acccggttta ctgctttctt ttgccatcgc tgccttcagc aggcttcttg ctatttatct
    27181 gccacagtta ggtggagcga ctattgctat tttattgggt attttattag gaaatacttt
    27241 ttttaaacag cctgttctag caatcggcac aaaatttgct gaaagcaaac tattagaatt
    27301 ctctgttttt ttactaggtg caactgtcac agctcaaacg attgctcaaa ttggtgtaaa
    27361 aggaattgtt tttgtgttac tgcaaatgtc agtcactatc atcggtgctt acttgattgg
    27421 taaaaaactg caattcagcg atacttcttc tttgatgatg gctggaggaa acgctgtttg
    27481 tggttcttct gctattgctt caatcgcccc ttccatccat gcgaaagagg aagaaaaagg
    27541 acagatcatc acactagtca atctactggg tactgtgatg atgttgactc tcccttttct
    27601 tggattacag ttgtttggtg gaaatctcat tgaaaaaagt gcacttttgg gtggtacact
    27661 ccaatctgtt ggtcaagtag tcgctggggc aagcttactt gacaattctg ttgtcgaatt
    27721 cgccatgcta tttaagattc tacgtattat gatgctcgtt gttgttgtct atctgtttga
    27781 aaaattcatg cacaagaaac aaccagctct gtttgaaacg ccaactgata cgcagaaaaa
    27841 acgaaaatta ccgcttcctt ggtatgtatt agggtttgtg atcttttgtt tggtcaacag
    27901 cttgttttct ttacctgtag ttattgacca atcggcacat tttatcagca gctggtttga
    27961 gatcactgct ttagcggcaa ttggtctgcg tttagacttt gcaaaattca tgaaagaagg
    28021 tacacgcttc ttatcttatg gattagctgt cgggcttctc caaacagtga tggctttact
    28081 atttatttgg ctgatcaaag tttagaatga acatgaaaaa acagttgtga ttctcgcatg
    28141 gaacaatgtc cgaatcacaa ctgtttttaa ttttgcagat atccttctaa caacaacaat
    28201 tggcgtttga tttcaacccc atctattgcg tttcccatat atcctgtcag ttttccattt
    28261 tgcccgatca ctcgatgaca aggaataacg attggcaatg gattggttcg atttgcctgc
    28321 ccaatcgctc gcacagcttt cggactatca acagcaacgg ctacttcttt atacgttcgg
    28381 atttctccat aaggaatggt cgacaaagct ttccagacat tttgctgaaa aggcgtacct
    28441 ctctttatag ataaaggaac atcaaattct tttctttttc ccgcaaaata ttcttcaaac
    28501 tgttcttgtg tgcgcgttaa aattcgctga ttcgctgatt cgctttctga aattggctga
    28561 aaagatacag cagtcaatcc ggattcatct gcatctaacc ataaaaagcc gataggtgtg
    28621 tgtattttca ttttgtttgc tcctagtcaa tagactggaa cttcctcctt tttctctatc
    28681 caaaactact tgccaactaa taaaaattgt tcttaaaagt ttgataaacc gaggaaacat
    28741 ggtaaactaa atacgttagt ttacaaaaag aatacctgtt cttttacgta aaatcaaatt
    28801 ttaaaggtgt tatttaaggt ttattaaatt ttgaatgtaa accatatata aacatacgat
    28861 tgaaaggata gaaacgatga aagtatcaat tgttgtccca tgttttaatg aagaaaaaac
    28921 tgttcctctt ttttttgatg aggttgaaaa attcaaaggt gcccatgagt tcgaatattt
    28981 gtttattgac gacggatcaa aagacggtac gttagcagca atcaagaagc tagcctcagc
    29041 ttatccttat gtccgctttg tctcattttc cagaaatttt gggaaagaag cggctctgta
    29101 cgctggattg caagcttcta caggagattt agtgaccgtg atggatgttg atctgcaaga
    29161 tccgcccgaa ctgcttcctg agatgatcaa ccggatcact acttctgata tcgattgtgt
    29221 cggcacccgg cgttcgactc gtgaaggcga gcctgcgata cgcagtttct ttgcgaaaaa
    29281 attctaccag ttgatcaata aaatcagcga tacagaaatg gtcgatggcg ctcgtgattt
    29341 ccgcttgatg actcgtcaaa tggtggatgc cgtcctagaa ttaacagaat acaaccgatt
    29401 ttcaaaagga ttatttagct gggtcggatt taaaacagaa tatatttctt atgaaaaccg
    29461 cgaacgtgtg gctggcgaaa catcttggtc cttctggaaa ttattcaact actcgattga
    29521 tggtatcgtg aacttctcgg atgcaccgtt aacgattgct tcatttatcg gcgctttgtc
    29581 ttgtgtcggt tctggtattg caattttgtt cattattttg cgggcattgt tgtttggtga
    29641 tcctacatca ggatggcctt ccatggtctc gatcttcctg ttcattggtg gaatccaatt
    29701 gttatgtctt ggaatcatcg ggaaatatat tgggaaaatc ttcttagaaa cgaaacagcg
    29761 tcctgtttat atcataagag aaacagaaaa agtgaagcca aatgaattga agcctcacca
    29821 ataatatacg tcaaatgaag taaacatttt tttaaatgaa aaaggactgt gacaaaagtc
    29881 ttgtcacagt ccttttttcc gaataaatgg tgttccagaa gtagcttctt cggaaataag
    29941 ccgaaatttc acaaaaattt gagaagcaat tttcgtaaat tccttcttat ttcttgaagc
    30001 tgaccacttc tatcacaacc tctttcatat cttattactt cttcattgct gcttttagtg
    30061 ctgctgctaa tgggctttct tctggttctt ctgcttgtgc atattttttc agcaagcgtc
    30121 gttcttcatg tttggtcatt ttcttcttct gctctttttt atcaagcaat ttttctgtcg
    30181 ttccatcgta tttacaacgg aaataagcac cgtttttacc ttcgatgatt tccattttcc
    30241 ggtgacattg cgggcatcga tgattagaga cttttggatc ttttcttctg cggtagttgc
    30301 aatctgaatt ggtgcagaca tagattttgc cgtcacgtgt gtttttctcg cgcagattgg
    30361 ccccacattc tgggcatttc ttttgggtaa tcgagaaatc ttgatattct tgtttgcttg
    30421 atttgatctc attcaccaag cgttttgttt ctttttcgat tccattcaag aaggttcctg
    30481 cttgtttctt tcctgcagca atagcttcaa ggtctttttc ccagctttct gtcaaatctg
    30541 gtgttactaa agagggattt accaatacta ataattgctt acctttagga gatacttgca
    30601 gtccttgagg ggtacgttcc atcagttcag atttgattag tttctcgata atctctgcac
    30661 gcgtagctgg ggttcccaga ctgtattttt ccatttgacc aagcaagctt gcttctgaca
    30721 atggtttagg cggtgcagat agttcttttt tgatggcgaa atcgggattg attctcattc
    30781 ctttttccca tttgactgtt tccgtctcag tttcagtttc gcctttccat cctgcttgga
    30841 cgacacgatt ttgccgaaaa atgaatcgtt ctttaccaaa ttcaaccgta acttttgttt
    30901 ggctgacttt atggggttga gcaaacagtc ctaaaaaacg agagacaatc atttgataga
    30961 tttttcgctc ttcattactt aatttttcat aacgtgctct gttttcagtt ggcaaaagtg
    31021 catggtgatc ggtcacttta ctgtcttgga atacttttgt ctgttggacg atggctccgt
    31081 ttttcaaata ctgcttgacc tcaggagcaa agtcgctgac tgcttgcaat cgttctttca
    31141 tcgtactttt catgtcattt gtcagatatt tgctgtctgt acgcggataa gtaacgatct
    31201 tatgggtctc atacaaactt tgtacaagac ttaatgtttt ctttgcagaa tagccatagc
    31261 gttgattggc ttctctttgg atctctgtta aatcataagg caatggcgca gattccgttt
    31321 ttaatttttc ttggacttct gtgacagttc ctttgcttgt actgatcaat tgaacaagtt
    31381 tttgtgcttc ttcttgtgtt tttaaagcaa attgattttt ttgaagcatt ttggcttgtt
    31441 cttttccagc ttgcaacgtg atcgtgaaat acgtttgtgg acggaactgc tcgattttct
    31501 tttcttggtc tctcactaat gctagtgtcg gtgtctgcac acggcctgct gataaattat
    31561 ccgcgtactt cacagttaag gctctggtca cattcaatcc taccagccag tccgcttttg
    31621 cccgggcaag agcagattca tacaatgcat catattcttt cgcaggtctt agttgcttga
    31681 atccagtttt gattgcttta tctgtttgag aagagatcca taaccgcttc actggtttat
    31741 tgaaatgcac atactctaag atccagcgag caacaagttc cccttctctt ccggcatctg
    31801 tcgcaatgac tgcttctgag acatcttttc gctgagccag ctgcttgatt gcttttaatt
    31861 gatgtcctgt tttaggaagt ggtttgattc ctagtttttt agggatcatt ggcaacgtgt
    31921 ccatttgcca gctctgccat tccttattca gatcttccgg cattttcaat cctaataaat
    31981 gaccaagggc ccaagtaacg atcaccttgg gtccttcata ataatttttg tgcttttgat
    32041 tagcaccaag caccttgctt aggtctttcg caacgcttgg tttttccgct agaattagtt
    32101 gtttcataaa attcctttct gctttctact gtgatgggct gatgattttt caacaacgca
    32161 agtcccttgt attgctgtaa atcatcgtca cactcttcac accagcgctc atctccgtca
    32221 ttccaaaagg cgctgagaaa gttacttttt gcattgatat attcataatt ttgatggatt
    32281 tcgttccatt gtttttcgta cgcttgtcgt gcttcttcga aagactcgaa tgtttcttct
    32341 tcttcaatat cttcttccca gtcttcaaaa aaccaccaag gctcattgtc cccgaacatg
    32401 gtaattactt gatacatact cgtgctcctt ctttcagctt ttctagactc atcttagtca
    32461 cttttcaaga aagttgcaag aattttctct tataaaaggg tcatttaatg aacatcttaa
    32521 aattgttaca aatgaatctg attgtttaag gcaaagtagc gataaagtta ttgatcatcc
    32581 aaaaatagct gtcttctgga tcgattgttg gttcttttgt aaagtatcct aaaaaacgta
    32641 aggaaagata accgtggatc atactacgaa gttccctgct tcgatgaact ttttcttctt
    32701 tcgttaattg aaaagcctca aatatctgca aaatgatctg attcgtttca tggattccat
    32761 ctaataaaac agcttcattg gtatgcggta cactgatcag taactcatac actgcttgat
    32821 ttgaaaaagc aaaggatcga taagtttctg catagatctg cagtgcttcc tgaccacttt
    32881 ttcccacaag agcccgtcgc agctggtcat taagttcctg cagaagtttc gctgttagcg
    32941 ctgttttgac atcacgaata tttttgaaat ggttatacag cgagggagcc ttgatatcca
    33001 agcgtttggc taaatgctga aaggttattt gctgaacatc catctcttct gctagttctc
    33061 gaaagcagtc gatgattttc tcttgagaca gatttctttt tttcatttcc atgtttcctc
    33121 tcataaaata aatccttcac tctttcagtt taccacgaaa aagaaagaga aaaaagagac
    33181 tttcattgat aaactacata ttgtagttta taataaagag ctgtagatga aaattttcag
    33241 aaagaaggag tctaattggc tgcaagaata aaggaaaaat tatttaggaa aagagaaact
    33301 tgggaacaaa acttgtttgt cttatggttt ggaacattta tggctggtat cggatttagt
    33361 ttagtcatgc cttttatgtc actttacata gatacgttag gtaattatag tacgtcacaa
    33421 ttgaactttt ggagcggatt gactttttca tctactttct tggtgactac gcttatctct
    33481 ccttggtggg gaaaattagc cgaccaaaaa ggaagaaaat tgatgctgtt gcgtgcttca
    33541 ttaggaatgg caatcgtcat ttctttgatg ggttgcgtga ctagtgtgta tcaattagtc
    33601 gcattgcgtc tgcttcaagg gattttttct ggttatatca gtaatgccac tgcccttgtc
    33661 gcaactggga cgccaaaaga aaaaagtggt caagttcttg gaaccttagc aactggttct
    33721 gttacaggaa cattacttgg accgcttctt ggcgggatct ctgcttcagc gtttggctat
    33781 cgccctacct ttttcattac agggatcatc ttatttttcg tcttcttgtt gagtctgttt
    33841 ttcgtccatg aaaaatttgt cccagtgaaa aaagaaaaca tggtttctgc caaacagatt
    33901 ttcaaagact tgaaatatcc acacgtcgtc atcggtatgt tcgtcacaac gatgatcatc
    33961 caagcatcca acaattccat tagtccaatc atcagtctgt acattcgcca attgctgcat
    34021 ggacatggga atgttacgtt gatcagcgga atcattgctt cgatacctgg gattgccact
    34081 ttgatagccg ctccaagatt tggtcgctta ggtgacaaga ttgggagtga aagaatactt
    34141 gcgattggtt tgggttttgc gattctggtt tatatcccaa tggcattcgt cacgaatgtt
    34201 tggcaattag ctgccttacg ttttttgatt ggtatctctg atgcttgtct gctccctgct
    34261 gtccaagcat tgatcacaaa atattcgcct catcaagctg ctggacggat cttcagttat
    34321 aaccaatctt tccaagcaac tggtaacgta gtagggccta tgatcggctc cagtgtttcc
    34381 agtgcatttg gttatcgtgg cgtctttctt tcgacttctc ttcttgtttt ggtcaacttc
    34441 ttgcttgtac gacacaatac acaagagatc catcagcaag aaactgcaga agaaaaagct
    34501 tcaggagtct ccatagcttc agggcactct ccttctcata gacaataagc gtaaatgaaa
    34561 aacactgctt gaacagttgt cacagactgt ccttgcagtg tttttgttta ggcctgtttt
    34621 ttcaagaact cagataagag gaataatccc ttttccaagg tttctttttt acaacagtaa
    34681 cctagtcggg catgcttcgg taaatcaaag gcacttcctg gtactaatag tactcctgtt
    34741 tcttctaata aattgataca aaatgtctgg tcatcttctt cgatggctaa tttaatgaaa
    34801 gaagtagaga cgtaattggg agcgacaagt tcaactttcg gttcattggc tacccattgt
    34861 tttaaaatca caaggttctc tgtaatgatc tttttgtttc gcgccaatat tttttcttta
    34921 ttcttcaatg catgtacagc aagatcatct gacaggactc cgccgcaaat catcgtgtag
    34981 tctcgatact ttcgaaaaac ttctgccaac tcaggtccag tagctgtcca gccaatacga
    35041 atacctggaa tggagtaggt tttggatagg gaattggttg ctataccttt ttcatagaca
    35101 tctacgatcg acaagaattc acctttatcc gttaaaggcg catatacttc atctatcaat
    35161 acatatgcat ctactgtacg agcaatttct gcgatttttt ctaaagtttt ccgatctagc
    35221 aatgtgcctg taggattgtt tgcactattc aaacagatga tttttgtttc aggtttgact
    35281 aaggcttcta gctgttctaa atcaaactgc caatcttctt cttccttcaa atgaacaaag
    35341 tcaacagcgg cacctaaaga tttggggatg tcatataatt gctgataagt aggaagcatc
    35401 gaaacaacat ggtctcctgc ttccactaac gcgtatagag ctaaaagatt agcaccagtc
    35461 gctccattcg tttgtaagat gttttccgga tcgacggttt gataaagaga agcgacttct
    35521 tgtttgaaaa catctgatcc ttcgatccag ccatagtcca atggttcgtt tttgcgtttt
    35581 tcgaaaaatt tacttacgct agtcccatct aagccaacga gttcgtctaa tgtcaatgct
    35641 tcgatcgagc tttgtgcaat atcatatacc gctttctttt cccatttatt tagccattct
    35701 tctacaccga aatttgcgat tttcatgttt ctttccccct tatatcttga tccagcctac
    35761 agcaagcaac ccgattgaaa gcagtgcggc cacacaaatc agcccaatca ttactttttc
    35821 ttttcccgta atttgatgtt tggtttcacg acaagcgatc cagtagaagc aaaaaccagg
    35881 aagataggca atactacata aaaggacata agaaaatcct gctaaaatga tgcccatcaa
    35941 ttcaaaaact acagcaatcc caccgatcac tacttgtttt ttgattcctt cttttaaaga
    36001 aaactggact tgatagatcc cgacaagtag ataacaaatc aaaattgccg ctgtacataa
    36061 agaataggca aattgatagg cataatcagt aactaagaaa gtcaataaga atagattagt
    36121 caagattgca gtaacaacta acgaataagt tggggcattt tttttattcg tttttcccca
    36181 acctttcggc aacagaccgt ctcgagccat caacatcgtt gtttctgctg ggagcatcgt
    36241 ccaagacaac caagaaccaa tgatcgaaat aatcaagccg atattgatca gcgctgctcc
    36301 ccaatttccc acgattcctt ttaaaatatt tgccatagca ggttgtgaaa tagttgctaa
    36361 ctcttcttga gataagacgc cgtatggcaa gatcgaagca aggatataga taaacaataa
    36421 acaaagcaga ccaatgatcg atgcttgctg ggcttctgaa cgtttcttcg cgcggttggc
    36481 taaaacactt gcgccttcga tccctacaaa gacccacatc ataaccatca aacaaccttt
    36541 aatctgcaac cagatcgttc cttgctgccc tgttccattc actagattat cagatacgtt
    36601 accccaaaaa tcagcagtga atatattcac tttaaatgcg ataaatacaa atattaaaaa
    36661 taggaataat ggcactaatt tacagatcgt cacgattgta ttgatgacgc tcgctccttc
    36721 aactccattg tttactaata aagtcagacc ccaaataaaa atacttgcaa ataaaataga
    36781 aggaacattt tgtccacctt tgaatatcgg gaaaaattct cccatggcgc tcatcagcat
    36841 cgttgcaaaa gcaacatttc ccagccacgc agacaaccag taaccccaac cactgatgaa
    36901 gccacctaat ttaccaaatg aagcttccgc gtaaccgaaa ataccaccat ctagatctgg
    36961 acgcttttct cctaaatgat tcagcgataa taccaaagct aaaataccaa tcccaacgat
    37021 tatccatgaa aggatcgctg gccctggagc tgcagaacta gccagatcac ttgtgatccc
    37081 aaacacaccg cttccgattg acgaactgac aaccagagca accagtcccc atttgctaat
    37141 acccgtcgat ttcttttcca tttccatcac cctcacttat aaaattgaac aaatcacttg
    37201 caaaagattc ccttctattt tgcaactgct cttgcttaac aaaaagcaac tttattcata
    37261 ttattggata ttatgaactt tttacacaag tatttcaagt ataaaatgaa taaaaattaa
    37321 ttttattgca aaaaaacagc tatgctatcc aaaagaaaag gtgtttcttt tgttagccat
    37381 agctgttttg attcatttaa tatcgcttaa acgtattgta aaacttttgt ttcttgatat
    37441 gcgtggtcga tcaaaccacc acccagacat tccattccat cataaaatac aactgcttgt
    37501 ccaggagtga ttgcacgtac aggttcgtcg aatacgactt ctgcacgatt atcatccaat
    37561 aagcgaactg tcacaggaac gtcttgctga cgataacgga atttcgctgt acacttgaat
    37621 tcttttggca ttggttcatt cgtcgtaaag tggatttcac ttgcatccaa gcttgtggca
    37681 tacaatgcag gatgatggaa cccttgcccc acatataatg tgtttgtcgc tagatctttt
    37741 cctacaacaa accagggttc ttgcgaatct cctccgccac cgatccctag tccttgacgt
    37801 tgaccaatcg tataatacat caagccagca tgttgtcctt tgacttcacc atcaagagtg
    37861 accatatttc ctttttttgc tggcagatag ttgctcaaaa attgtttgaa gttcttttca
    37921 ccaataaagc agattcccgt tgaatctttt ttcttagcag tcgcaaggcc tgcgcgttca
    37981 gcaattgccc gtacttctga tttttccatg ccgcctagag ggaacatcgt ttttgaaagc
    38041 tgttcttgtg ataattggct aaggaagtaa gtttgatctt tattattgtc tactccacga
    38101 agcatgtgga ccacgccgtt ttcatcgcga gtgacttgcg cataatgtcc agtagctaca
    38161 taatcggcgc caagatccat tgcataatcc aagaatgctt tgaatttgat ttctttgttg
    38221 cacatcacgt ctgggttagg tgtacgtcct gcgcggtatt cggctaggaa atattcaaat
    38281 acacgatccc aatattcttt ttcaaaattc acagagtaat aaggaatccc gatttgagca
    38341 gctactttcg ctacatcctt ataatcttcc gtggccgtgc atacaccgtt ttcgtccgtg
    38401 tcatcccaat ttttcatgaa tattccgatc acgtcgtatc cttgttcctt taacaaaagt
    38461 gctgttacag atgagtcgac accgccgctc atccctacga caacgcgtgt tttgctgttg
    38521 tctgtcatga tatcaccatc atttcaatta gattctgaaa catctacgag ttgaaggtcg
    38581 caacttttca gtattttaca ttatacgtca tatttctgaa aatttcatcc cttaattatc
    38641 aagtcgtaaa aatactgttc tactggacct attcagtaca caaacatgat agtcaaccaa
    38701 aaaatcactc atcttttgag cattcgatat aaaaaattgg catactcata aaaagggcca
    38761 gcctttcggc aataaggaat aattttataa attgtgaaaa actatttttc aaaattgctt
    38821 cttatcgctt aaagctgcac gtctcattta caaccttttc tttttagatg ttatgagttg
    38881 ctcagataag tgattttgtt tactctaaga aaaaagggag gcaaaagata catgaattac
    38941 tttatcagtg atatgcactt tttccatgaa cacttattag gaaaaaacga ctttgctccg
    39001 cggctctttg caaatgtgga tgaaatgaac caacagttga tcactagctg gaatgcagta
    39061 ataaaagaaa ccgaccatgt ttatcatcta ggcgaccttg ctatgcatcc gcaatatgaa
    39121 aaagcaaatg cagaaatttt ggaactggtc actcaactgc aaggaacaat ccacttgatc
    39181 aaagggaacc atgacagtcg cgcttttttc cgttatttag aaaaaaatga tcctaggctt
    39241 actgacggaa gtcccaaatt ttatttttat gatgtaggtg ccatcgttaa attcgaccat
    39301 caacaatatt acttgactca ttatccgatg ttgctcgggc ctaacgacac tatccgcaat
    39361 cttcatggac atatccatca ttacagcgta cctatcgaga acgatgtcaa tgtaggcgta
    39421 gacgcaccgg aaagagaact cttaaaggaa aaactaccat ttggcactcc gttatctgag
    39481 caacaaatca aagaaatcta tgaagcaaag aggaagtacg ataggtcgtg aaaaaactgc
    39541 cctatatcaa gtattaaaca aataaagata attactcata tttttcattt gagtaggctt
    39601 attgccacag gaacattagg atcagaaatg gagttgtaac aagacttctg tcacaactcc
    39661 attccatact attcgtcttt ttgctcatgg tgttctttta ccagtttttt ctgtaattct
    39721 ttatcataat ttcgggcagc tgacgttaaa aataaaacga ttccgcataa taaaatcccg
    39781 attccggaaa acaagaacat tttttctacc cctaaacgat cagctaatgg tcctgcaaat
    39841 aataatccaa ttggacctgc caggttcatc aaagagttga agttccctaa gacacgacct
    39901 aaaacattcg attcataact ctgctggatc attgccatca gcagtgtatt gaaatatggc
    39961 gttgcacaac ctgctcctgc attcaagata agaaagtaca agaacccttg actatcgttt
    40021 ggaaccaatc cgcttgcacc gatcgtcagg cccataatga tgtaggctat aataataggt
    40081 ttcattcggt ctttccatgt tcctataaaa ctgatcagtg caccgcctaa gagcattccg
    40141 actgcgtaga ctacttccac tgctcccgcc tgtccaacgg aaccaccaaa gtaatctagc
    40201 gtcatcaatg gatacagact gattgctggc atgaacaaca gcatcacaaa tgcaccattg
    40261 atcgttatgt accataaccc tttattatcc atcaattgct gcagcccaaa ttttgcatct
    40321 ttaaaaatag taagcggaac ttccaatatt tcaggagaaa cttttgggat cttcacaaaa
    40381 atcaataagc cgacaccaaa aactgccccc aatacatcta ataaaataag gtaattgaca
    40441 ggaacgactg aaaacaaagc cgcacctaga gctggcgcaa tgatgaaatt cgctgattgg
    40501 accattccta actgtccatt cgtccttgtt atgtgagaag atggaacgat tgtcggcata
    40561 atcgactgga tcgttggcat ttggaatgtt tgtgcgaccg aacgcataaa caaagacaca
    40621 aaaactagcc aaatcgggaa ggattctgaa atcgttccga ctactgctaa aataagcgcg
    40681 aaaatcgcta caataatatc cgtgacaatc aaaagagctt ttttatccca gcgatccact
    40741 agcggtccta caaatgggct tagtaaaacc atgggaatca ttcctagtaa agtagcaaaa
    40801 ctcaaaattg tcgccgaacc ggtttctctt gtcaaatacc agatgatcgc atattggacg
    40861 accatactag tgattcctga caaaaactgt cccgataaaa agaacaaata atttctcttc
    40921 caattcgtta aaacgaccga ctgttcattt tccataaaca tccctctttt ctttttcatt
    40981 ttgtatagcg tttgcacaac aatcattata cgggattctt ttttcaaaaa ataccttttt
    41041 ccctaaataa caatcgtttc aatttaaatt tctttactta gaaacaataa atcagcaaaa
    41101 tattaaaaat aacaacatgt gttaaattta aaaataaaaa agacaactaa tttgcgtcgt
    41161 ccttacaaag ttagtcatct aacaataggc cgtttcaaaa ctagttgtct ttttatatcc
    41221 acagatcatt cgactttttc gaataaccca cggctaatca tcccatccat cagaaaataa
    41281 aatttatctt ggctcatttt ctgttttgga tctttgaaaa tattgactgc tttcaatcca
    41341 tttgctgtag tgatcgacat tttcaatgtt tgaatatctt ttgatacagt gatttttaat
    41401 ttgaatcctt ctttgctttg cggcgtggca tctaatggtc ggatcaattg ataattgcct
    41461 ccgtttgttt ctgtaaatcc attatcgcgc aatgtatatc tttttgcatc aggatgcaaa
    41521 cgatagctaa ttggtgcgcc cagtaccgtt gctgttgttt caaatgccat gattttcacc
    41581 tcgataaaat tagtttctct ttattataaa agtttatcct gatttttact aggtttttca
    41641 gttaagttcc ctaaaaaatg aaggcgttct ctcagacatc tgttcatata agaatgactt
    41701 cactagttat tttttgacag cacgaactaa ttgatcaagg aaatactgga tgtcgtcttc
    41761 ggtatttccc aaaccaaagc tgatacggat ggattctttt agtatcggtg tatcttctcc
    41821 atacattgct tctaatacgt gtgaaggctc gatatttcct gctgtacaag ctgaaccagt
    41881 agaaatagcg accccattaa gatcaagctt catcagtagc aaatcatttg cttcgccaat
    41941 taagcgaaga ttcaacacat gagggagttt attcgttaaa tcaccattta cttgataagg
    42001 gatttcgttt gcttctaatg tatcaagaat caattgctgg aatcctttat atttgttgtt
    42061 acgtgcttca cgttcttcag gtgacagcag ttcaactgct tttgccatac cccagatccc
    42121 tgctaaattt tctgtacctg cacgccgctt ttcttcctgc tccccgccta aaagcaatgc
    42181 agggatattt actccgtctc gtttatataa gaaaccgacg ccttttggcc cattgatttt
    42241 atgagcagag atacttaata aatcgattcc taattcttct ggatggatcg tttggtttcc
    42301 gtacgcttgt accgcatctg tatggaaata agctggatga tccgctaaaa gttcaccgat
    42361 ttctttgatt ggcatcaaat ttccgatttc attgttcccg tacatcacag agaccaagat
    42421 cgtatcttct cgtaacgctt ttttgacctc ttcgatcgac agattccctt tttcatctac
    42481 aggcagatat gtaacgtcaa acccctttgt ctctaaatat ttcatggtat taagaacagc
    42541 aggatgttcg atagctgtag tgattagatg tctgccttct ttttgacgcg agaacgctgt
    42601 ttctaagata gctgtattat ccccttctgt tcccccactg ttaaagatga tctcgtgagg
    42661 ttttgcttgc agactgtctg caatgatttg tcttgctgtt tccaattttt catgcgcgtg
    42721 gcgaccaaat ccatgtatgc ttgaaggatt tccaaacgtg tcttgcatga ttgccgtcat
    42781 cgcttcaatt acttgtggat gcatgggggt agttgccgca tgatccagat aaatagtttt
    42841 cacttcattc atcccttcca aattattgct aggcacattc tagcataaaa tagcgaacaa
    42901 accaaagaag agctcatttt tgtctagagg acgtttcatg ggcatagaaa aaaggagctg
    42961 tgacaaaagt cttgtcgcag ctccttgaag ctgctcactt ctgtcacaac ttctttccct
    43021 cttttttttg tttattcgaa ttctttttct tccagacgga ataacggact catcggtgta
    43081 ttttcatgga tgcgtttgac cgcttcaccc attaattctg aacatgtaac gattgttaag
    43141 ttttctggat gacgattttc ttctgtgaaa acagaatcag tgatacaaat atctttgatt
    43201 ggtgcattgt ctaaaatact tttcgcatga tcggacaata atccatgtga cgcacaggca
    43261 tatacttctt ttgcgccgtt ttcttttaat acatttgctg ctcgtgcaag cgttgctcct
    43321 gtgttcaaga tatcatctac catgatacat gtctttcctt gaacatcacc gatcacataa
    43381 ccaccctcag ttgaagcatc atctgcatga tctacgatgg ctaatgtgct gttcaaatat
    43441 tctgaaagac tacgtgcacg ctgaacaccg ctgttttttg gcgaaacaac tacgatgtca
    43501 tctcccgtca gacctaattg acggtaataa tgagcaaaca acggcatcgt aaataaatta
    43561 tctacaggaa tatcaaagaa tccttgtact tgaaccgtgt gcagatctaa agtcagtact
    43621 cgagttgccc ctgcttcttc gatcaagtta gcgatcaatt tcgcagtgat cggttcatga
    43681 ggtttcgccg tgcggtcttg cctagcatac ccatagtaag gcaatacgac attgatcgtt
    43741 ttcgcacttg ctcgcttcat tgcatcgatc atgatcagta gttccatata gtaatcattg
    43801 acaggtgcat tcgttgattg aacgatatac acatgatccc ctcgaatact ttcttcgata
    43861 ttgatggaaa tctcgccatc actaaattgc ttcacgacgc ttttacctaa ttctgttccg
    43921 aacactttcg cgattttttc agctaatgga cggttgccat tcaaactaaa aatcttcaac
    43981 gtgtcatcct gatacttatt actcatgtag tcctccccaa aacttctcta ttcttcgata
    44041 gtttaacata tttttccaag attttctgtt aatttcagca aattcttaag gaagtgaaac
    44101 tgttccgtta ctccaactgg caggaatgac tttatgataa tcgccccagt tgtcgtgtac
    44161 tttgtaataa cgttctcctg tttcagtttc aaaataagcg tacgctgtca cccaatgatt
    44221 gccatatgta ctgccaagta ctttcaaaat accaatcatc acaggtttgc cttcacgtat
    44281 acgttttgta gctcgctgcc atgaacctag aagagttgct cgtgcacgct catgattgcc
    44341 attcttcttt aaaaaactag aaatccctgt actaacctga aaaggaatcg taggaagtcc
    44401 tagtggttgg atctggctac gcaatgcctt cgtcaaaacc aacgaatcag ccgtattttt
    44461 cttgcgaatc tcatttggaa gcatccaccc cttacgatag tcttgataat aggcaaggag
    44521 aactgctgcc gcgtaagtac cacaaagata gcctgagggg gtagcccatt tcttatacct
    44581 caaaaaacgt tcttctggca atcccaccca gcaatttgcg agttcctttc ctgacctttt
    44641 ttcttcgatc aaaacgggaa tatcttcttt tctgttgatc catctagata actcgattgg
    44701 ctcttcattg atcagcttcc attttttaca agaaagaccc tcttgataag tatattttgc
    44761 tggagaatat tctaccggat gtcctgattg atcgataatc acataacttt gatcttcaaa
    44821 aaccagagct aaaaaaagca atttactttt tcttgactgc agctgctgag tgctggctaa
    44881 ttttttaatt tttttatcta ctttgaaata taaaggttta tccactactt gattcagttg
    44941 ggatcgcctc ctttttttca ttataagtga aggattgaaa aaaacaaatc agtttgattg
    45001 ttcgaatttt caatttttta tgttctattt gttaattcct tcattttgta agataatggg
    45061 cacacgaaac aaaaaaggag cgatcgatga atgaacaaag aacgattgaa acaagatttc
    45121 tatgaagcag tcaatgaaga atggcaaaaa acagcaaaaa tccctgcaga taaaccagct
    45181 acaggcggtt tccaagattt agttgacggg atcgaccaac ttttgatggg agaaacagac
    45241 gatctgcttg cccatccaga aaaagtgtct tcagaaaaaa tgaaacattt ccttgcatat
    45301 tatcaactgg caaacgatta tgaccgaaga aatgagttgc atgctcaacc gcttcaacct
    45361 ataatcgaaa aagttgaatc attgcagtct ttcgacgaat tgaataagca atttccagaa
    45421 tggctgttgg atacattacc attgccattt aatctggatg tagatgcaga tatgaagaat
    45481 gcgcaaacga acgccttctt tgcttatccg ccttctttat tccttccaga taagacgtat
    45541 tatgcatcag accatcccaa cggtgcacaa ctaataggcg ttttctttga tatggctgtt
    45601 cagttattag agcttgccgg caaagaaaaa agtcaggcag aagcaatcac ggaacaagca
    45661 gtgcaatttg ataaattgat tgctcctcat gtaaaaagtg cagaagaaaa cgcagattac
    45721 agcaaaatgt ataatccgca atcttttgat acatttatta aatacacaga taaactggac
    45781 ttgaaaaaac ttgtcacggg tttgattggg acaactccag ataaagtgat cgtaactgat
    45841 ccagtgtact tcgatcattt gaatgacatc ctgacagaag ctcattttcc gttattcaaa
    45901 agctggatga tcattaaaac agtacgttct cttagtggtt atctatcaga agaattccgc
    45961 caagtcagcg gaatctattc tcgcgtattg tctggaacag acgaagcaat gcctcagaaa
    46021 aaagcagcgt attaccttgc ctctggacaa ttcgatcaag tagttggcga ttactacgga
    46081 aaaaaatatt ttggcgaagc tgctaaaaaa gacgtagaac aaatggtgaa aaaaatgatc
    46141 gccgtttata aaaaacgtct agaagaaaat gactggcttg gggatgcaac aaaagaaaaa
    46201 gccgtcataa aattaaataa cttaggtatc caagtaggct accccgataa gatcccagca
    46261 ttattcgacc agttcaaaac agtacctgca gatcagggtg gtactttgct ttcaaatact
    46321 cttgttttca gcaaactcac attaaaagat cgtttcagca aatggaacaa accagtggat
    46381 cgttcagaat gggaaatgag tgctgacacg gtcaatgctt attatcatcc atttcggaat
    46441 gtgatcgtct ttccggcagc gatccttcaa gcaccatttt acagtctaga acaatcaagc
    46501 tctgctaatt atggtggaat cggagctgtt atcgctcatg agatttccca tgcatttgat
    46561 aataacggcg ctttatttga cgaatatggc aacttgaaca actggtggac agaagaagat
    46621 cttacacaat ttcaaaacaa agcacaagca atgatcgaag aattcgatgg tctgcctttt
    46681 gctgacggaa aagtaaacgg aaaattaacc gtttcggaaa atattgctga tgcaggcggt
    46741 ctaagctgtg cattggaagc agcaaaaacg gaatcagatc tttctatcga ggaattcttt
    46801 gtcaattggg caacgatttg gcgtacaaaa gcaaaaaaag aataccaaca acttttactg
    46861 caaatcgatg tccatgcccc tgctaaactc cgagcaaacg tgcaaccaaa aaaccttgac
    46921 gaattctatg aaacatttgg tatcacggaa caagacgcta tgtatctagc gccagaaaaa
    46981 agagtgcgaa tctggtaaga ggttgtgcca gaagtggtca gcttcaagaa ataagaagga
    47041 atttgggaaa atcgcttctc aaatttttgt gacatttcgg cttatttttc gaagaagtta
    47101 cttctggaat accatgtatt agaggttgtg aaaaagctgc ttagtttcaa gtagtaagaa
    47161 aaattttgtg aaaatggctt tccacatttt tgcataaatt tgacttacta ccgagaaact
    47221 ggcttttgaa caccgtttat cgagaggttg tgaaatcagc gtcctgacct gagtattaga
    47281 gaaaaaaacg gaaaaatagt tcctcatatt ttgccgtttg ttgagctaat accgagggtc
    47341 agctgattga acaccgttta gtggagagat tgtgaaaaag ctgtcctgca tcaagtaata
    47401 agaacagcca atcaaaagca gcaaggagaa cctcatctat aaaaagatag aaggaagtga
    47461 gacatctatt ggtctcattt ccttctattt ttactttcct cagtcaattg ttttacatca
    47521 taaaaggaga aattccactt atttttttcg ctgtttcatg acataaacaa ctacaccgat
    47581 taacaaaatt cctccagcta atgctagcaa cgggttatta aattctcccg tttttgggag
    47641 tccttgagtg ccattttttt cactttcttt tgctgtccta tccggatgag aaggttttcc
    47701 atttggtttt ccatttggtg attcatttcc tggattttct ctttctggtt tgtcatttcc
    47761 cgggggcaca tcggcagttt ctcgcacagt gatcgctttt tgctgggtaa cagattctgt
    47821 atgagcagac catttttccc catcaaatat ttccgaacga taagtgactt ctagcgtata
    47881 ttctcctttt gaaggtgctg aaaaaatagc ggtatgatta gaaaattgag cacttgactg
    47941 tgtttcaacg atttggatct tttctgggaa ataacgcata tcttcaaaga caggcgttcc
    48001 ttgatttggt gtgaaagttg acacaaaaac tgtaaaaggc ttcagttcaa tgatatttcc
    48061 ttctgcattc tccgccacac catttgcttc ttgtataata atcggattat tttgttcatt
    48121 tggttttgtc tgatttggtt cttgtacgat tgcatactct ggatattccg aagacggtga
    48181 ggtttctccg tcaaaaatag cacctacaga taatggaaga ccatccactc tttccttttc
    48241 tgtttgacga ttccccggtt taatctgcat cagtccatga acatggatac ttccattttc
    48301 atagcgcgta acaggctgct gaccttcttt cgaacatgta tttagagact cgatccaatc
    48361 ttttgatatg gtatgtccaa gagtattttc tgattgtttc tctcgttcat tccaatagta
    48421 gttcaacgag tggtagattt gatcttcgtt ttgattcaat gggcggatct gctctctcat
    48481 ctcaagattc tctgttcgga aagataagat accagaagca tggtagtctg tgtttcctgc
    48541 tgaagaggta taaagagcca cattatatga accgttatta aaacttgtac tgctattgac
    48601 gataatatct gttccgctat tggaatcgat tcctttcgca agattttcga aagacaaact
    48661 attgatcaat tcatgagggc ccgttaaaga agaaccgccc attttgaatc cattaccgtt
    48721 accttctccc tcaattcctg gtacccagcc gtttcgataa gcaactgagt ttttgatgat
    48781 tacttttccg atcgaacctg tttcattttt agcaaaaagg tcccaaccgt catctgcatt
    48841 atgatacgcg atacaaccgt caaatacatt tccttctcct attgtcagtt tggccgcaaa
    48901 tccatcggca tcttcaaatc ctggatcggc attttcaaaa gatgtacagt tcttgactaa
    48961 gttatgcgcg ggccatgctt cgaaaggatc atttgagcta ccgctgattt ggattcctgt
    49021 atttccattc cgataagcat gaatctcttc gatcaaatta tgatttccag aaatctgtaa
    49081 tcctttttgc atagctgcac tatttgtaat gtcaaaccct cgtaaacccc agtagtgact
    49141 gaacagtgtc atcccatttc cagttccttt aaaatcaagt acaggacgct tgttttctgg
    49201 atttttctct gcaatcaact gaatcgggtt ttctcttgtc ccgttaacgc cttttggaat
    49261 cgtcaatcct ctttcgaagg aataagttcc aggcgccatg acgattgtct gcccagcata
    49321 tgcgtatctc aatgcttgtg tcagagataa tggattttgt ctgcttccgt ttcctgcatc
    49381 tgacccttct ggtgttacat aaactgtcga atatttaggt ttacggtagt ccactgtatg
    49441 aagaatctct tttgtttcat aactagtcat ctctacgtat tcttctggcg gatagttttt
    49501 atctggcgta aaactgaaag taaattcgtt cgttccttcc atcagttttg tctgataatc
    49561 aaattcccga ttcgcagtga tagccaagtt ttttgcgttc ttaagcacct ctcctgttgc
    49621 tttattttta attgtcaata atccgtcagc atttgctcta aaggacatag tatgatcttg
    49681 gtttcctgaa tgattactag aggtcacagt gtaaatcgga tcaatcaagc gagtaggtct
    49741 ttcttgccca ggaggatctg tcgcaggatc tgagtaagca acttcgattc cttctacctt
    49801 gatcgtcata ttccttgctg cagcaaatcc tgcataaata accgattcat ctgaagcgta
    49861 taatttttcc cagtcataca tgatgtcaga agccatttct tctcctgttt caggatcgta
    49921 ataatatgcc tctaaaccag tattcgtttt tttcatctct acgtccagtt tagtaatcga
    49981 gttcgtggcc ggaaacagat tcccatgacc gtttccgaat atattataag aacctgtttc
    50041 tttttccaag aaccctgctg aagtctctaa aggtgttgtt tccactgaga cactcccagg
    50101 agctggcgca gcttgcggat cttcagatga tattcctgtg attgcccgtg tccccaatcc
    50161 aagtcgcatc gtatatttgc tgccgctcgt gttgaccact tcttgtctat ccgagtccca
    50221 gacatattcg atccgactgc ctagtatggc aaatgaattt gaataaaatg cctgcccaaa
    50281 caaatgattt tttggtactg cgtctcttac cattaaagca aatccttctt gggcattcgt
    50341 ataggtccaa gattctattt cgatcgtcgc ccgcatccta aagttgatgt ctttggggat
    50401 tgcttgataa taataggtca ttccatctga tccgcttgac tggaattttc cgccgttatt
    50461 cgtggaagag agccgcacgc cgtcttctaa tggttcaatg gcatacctac tagcacttgt
    50521 gctttctccg aaaacaaccc ctttccactc ttcatttgct tcttcagatt gcttttttgt
    50581 cttttcattt tctgattctt tcatcatagg atcatttcct tcttccgtat ccatatcttc
    50641 actagttctt ggtatttcct ccattgttga catcccttca atgttcacgt gtgcattttc
    50701 ttcgttcaca gactgttgtt cgttagcagc aacttcaacg acagaaatta aaaccggggt
    50761 actgagcata aggagattca tcattagcgc actgtatttt atacgttttt ttaacaagtg
    50821 tattcctccc gtaacaaatt agaaagcgtt tacttaaagt attacctaat ttatttttac
    50881 tgtcaataaa aaacaaaatt ataataagtg tattttataa aaagaaaaaa tataacttaa
    50941 gttgttgata ataaagagat ttattaacgt aaaaagaata agttttttta aaataacgta
    51001 taaaaaagag cataaaacaa agtcgtttgt tttatgctct tcttttatta ttttgtgctt
    51061 tttattttat caaatcactt tgttttttta taaaatttct gcgcctagtg tggactcaaa
    51121 atgtctcaat gcccattcat gtccaacggg atcgaaactt gccacggcat ctttgaaaat
    51181 atggagtttg tatcctagat tatacgcatc gactgctgta tgcaacacac agatatctgt
    51241 acatacgccg gtcaaataaa tatctgtgat ctggcgttct cgcaaacgga tgtctagatc
    51301 tgttccacta aaagcggaat aatgccgttt gtctatccaa taaacatttt cctcttgctc
    51361 atagtcttgg tataaacttt ttaaagagcc gtacaattcc cgtccacccg ttcctatcac
    51421 attatgcgga ggaaataagc ggttctccgg atgaaaggaa tcttttggat catgcgcatc
    51481 aatggcaaaa acgacaaaat ccttttgatc aataaacttc tttgtatgag cagtcagctt
    51541 tttttcaatt acttgtcctg ctgtcccagt agtcagcttt ccatcctctg caacaaaatc
    51601 atatgtgtag tcaatcgaga tcaatgcgtt catcttagtc ctccttatac gagatgtttg
    51661 acaaattcga tcaccatttc tgctgatcgt ttgcctgcgt cttcgataaa ttcgtcaaag
    51721 ctttgtgtcg ccgagtgatc tgctgtgtcg ctcattgcac gtacgatcaa aaatgggata
    51781 ttgaactgac gagctgtttg tccaacagcg gctccttcca tttcgcaagc taatgcttca
    51841 gggaaattcg ttaagatttc tttgatttta tctggcgagt cgacaaatgt atcacctgta
    51901 acgatcaatc cttcttttgc gttcaaattc gttgcttttg ctgctttaac catttcactg
    51961 cgcaaatatg tgcttgcttc ataatataga ggcattcctg gtaattgtcc tgggttgtag
    52021 ccaaatcctg ttgcatctgc atcaaaataa gctactttgt ctgatataac gatgtcacct
    52081 acttgtaagc cttcaccgat tccgccagct gaacctgtat tgatcaccat gttcacgccg
    52141 tattgttgga tcaacagact tgtggtaata gatgctaaga cttttcctat accggaacgt
    52201 acgacgatca cttcgtggtt acctaatgaa cctgaaataa ataaagcgcc tgcgcgttcc
    52261 catgataatg gttcgcttag gttctctctc aaaattttta cttcttcttc cattgcgccg
    52321 ataataccga ttttcatctt tttaattcct tctttctata taaatgcgat tgctaaaaaa
    52381 accacacata acattaggat aacaataata agagatttca tcaaaaaaga gttccatttg
    52441 gtcgtctttt cccgttcgct gatccttgtt ttcgtgattg gtttattctt tttgctttct
    52501 ttacgataaa agctggcaat ctttttttct tcttgctgat aagctgtttc tgcttttcgc
    52561 tgttttttta atgactcgct tgcttgtgct tgttgtcgct tgcgaagttc gcttcgcgta
    52621 ataagcggtc ctttggccat aagccgatcc ctctactttc ctttggtcaa tagttcccag
    52681 tattgaatcg cataaatcgt ctttgcatca caaatcaact gatctttcat cgcttgttgc
    52741 gcctcttcaa gagttagatg atacaactcc agtacttcgt cttcatcttg tgctaaagga
    52801 ttctcgacct tctctacccc ttgtgcatga taaatatgaa ggacttcatt tgcaaaacct
    52861 ggtgaaagat acatcgaagt aagatggctc agcgacttcg cacgatagcc agtttcttct
    52921 tctaattctc tagctgctgt catttcggga ttttgtcctt ctcctggatc gatttttcca
    52981 gctggaatct ccaaaatcac tttttctaaa ggttttcgaa attgtttgac aagaagcaga
    53041 cgatcttgtt cgtcaaaagc aatgatcccg acaccgccag gatgaaatac cagttctctc
    53101 ttcgaagttc ctccatctgg caaacgaact tcgtctacag caacatcaat aatttttccg
    53161 ctatagattt ctttgcgact gattgttttt tcttcaaatt gctcattgtt cagcatatct
    53221 tctcctgctt tctttgtaat cataactgct tttttttcat ttttcaattt ttctcaaaaa
    53281 ctccttatta gtttaccata gataaacctt agattttctc taaatataga aaatccttct
    53341 ttagtccgat actctttata gtagtccgta tgctaaaata agtatgtaat cgaataacga
    53401 aaagaattca atactcaacg ataaatgaca tggagggttt attatgataa aacgaaattg
    53461 gccgtggctt ctagcattgg tcttgctatt tctctttgtc cgaaacaata gtttttcttt
    53521 tgttctagga cttttattga taggtgtagt tttagttttg tggggactct ttggttcgcg
    53581 caggaaaaag ggaaaacaag aagaaattcc tgcactgact gacgaacttg aaactcacta
    53641 tgaaaaaagc ggtatgacag cgaatgaaat ttcatttttt cgacaaacaa tgaatcaaac
    53701 aaaaaatgag atcaatcaat tgcaaatgaa tatgcagcag acagccaaac ttaaagcaat
    53761 cgatctccgc catgatccag tcaaagcagc gaaagcttta ttcaaagaat tggtgaaaga
    53821 accaaaccga ctgcatgaag caagtcagtt tctttatacg catctgccga atctagttga
    53881 tttgacaaat aagtataatg agatcaatga ccatgagatc aaaaacaaac agacctatga
    53941 aaaactagaa gaaagcgcgc agatcatcga ccagctgtca gctttaatcg cacaagatta
    54001 tcaaaaattc gttgctgagg atctagatga tatcgacgta gagatatctg ttgcgaaaca
    54061 gagcttaaag cgtgataata aatatgaacc agaacaaaag gattaactct tttgttcata
    54121 aaagaagact cggaacattc agatgatgtc tggctgtttc gagtactttt tctaaagtag
    54181 agacattcat gtaagaatcg agaacagatt caacaaggag gaatttttta tggatcataa
    54241 accgactgaa acaaaagatg ttacaccagt taacgataca cttgaagatt tattgaacaa
    54301 cccgttttca actccaacag atacgctgac cacttcacaa caagcggaga ttgatcagct
    54361 ccaagagcaa cagacagctg ctcgtttaat tgacaaacta ccggcggaac gccaagaaca
    54421 agctaaacag ctagcagcaa aaatcgatgc taatgatgca cagtctgtca tcagctacgg
    54481 atcggctgcc caagcaaaat taagtgaatt ctcacaatcg atgttgaatc atgtgcaagc
    54541 acaagatatt ggtcctgtag gagattcctt aactgaactg atgtatcgtc tccaagaagc
    54601 caatcctgac gaactgcgtg ccggagaagg gaacatcttc cagcgtgtct tcgggaaggt
    54661 caaacaatcg atctatgaag tgacagcaaa atatcaaaag attggtgcac aaattgacaa
    54721 gatttcagtg aaattagata aagaaaaaga cggtctgcta aaagataatc tgatgttaga
    54781 acagctttac cagaaaaaca aagactactt tgatgcactg aatatttata tcgctgctgg
    54841 agaattgaaa atggaagaac ttcaaacaac gatcattcca gaagcgatga aaagagcaga
    54901 agaaactggc gatcagatgg atgttcagat tgccaatgat tacacgcaat tcctagatcg
    54961 tctggataaa cgtacgcatg atcttcgctt agctagacag atcacgatcc agcaagcacc
    55021 acaaatccgt ttgatccaaa acacaaatca ggccttggct gaaaagatcc aagcatctat
    55081 cgctacagcc attccgctgt ggaaaaacca agtcgtgatc gcattgacct tgcttcgtca
    55141 aaaagatgca gtaactgctc aacgccaagt ctctgaaaca acaaacgact tattgaagaa
    55201 aaattcagaa atgctgaaaa tctcagccat cgaaacagcg aaagaaaatg aacgtggaat
    55261 cgtggatatc gagacccttc aaaccactca aaatgatttg atcgaaacaa tccaagagac
    55321 attgcgtatc caaaaagaag gaaaagaaaa acgtcgtcat gcagaagtag agcttggaca
    55381 catggaagaa gatctgaaac aaaaactgtt ggatttaacc caatagatca cctttcgctt
    55441 gttactaaaa caaacgccca acaacagttt attacaactg ttgatgggcg tttttcttat
    55501 ctttcttcta acttctccat tggagtctat ttctcattca tcttgctgtg tccatagcca
    55561 tagccaaaat aaatgatcag tccaataacc attacgatac cgaacacgat ccatgtcaca
    55621 gtttgcagac gaagcatcaa tacaatacaa gtcaagatgg agacgattgg caatagcgga
    55681 acgaatggca ctttgaattc tccagctttt ggtttgccaa acatttttct caacttcagt
    55741 aagcctagac taacaagcat caaataggcg agcgccatga tattcgttag ttccgctaat
    55801 acattcaatg ggaaaaatcc ggcaaagaat acagctgcca caccagcggc ataagtcgct
    55861 tttttcggtg tacgatgctt ttgatcgatt tctgtcataa acttaggaag taagccatcc
    55921 ttgctgacag caaacagtaa acgagcaagt gaatacatca tcgagatcgt taccgtcagt
    55981 agcgttaaaa ttgcccctac agcgatcacc gcgcccactg ttccatgtcc tacatacctc
    56041 attgcaaaag ccactgggtc attgactcct agttcagtat acggaacgat tcctgtcaag
    56101 atcagcgtca cgatgatgta aaggacagta gcaatcagta tcgaaccaat gattcctctt
    56161 ggcacatctt tttgcgggtt tttgacttcc tcggctgcca ttgcaacggc atcaaatccc
    56221 aagaaagcaa aaaacacaag agctgcacca tctagcacac cggaaaaacc aaaaggcatg
    56281 aatggctgcc agttatcagg tttaacgaaa aatattccta caatgataaa caacgcgatg
    56341 ataccaaatt tgacatatac catggcatta ttcaaacgta atgctttctt ggcttcaagc
    56401 gacacgatgt aagtgacgaa tatcactacg agcaccgcaa tcaagtcaat gtatgtacca
    56461 ttttccggat tgtacccgcc agttaatgct tgtggaagtt cggcccctaa acttttcaaa
    56521 aaaccttgca tatagccaga ccatccggaa gcaacagagg aaaccgctag taaaaattcc
    56581 ccgatcaaca accaccctgt cagccaggca gcaaattcac caaatacaac atacagatag
    56641 gcatatggcc caccaatcac tggcactcgc gaagcaaatt ctgcgaaact tagtccagac
    56701 aaaatgacaa cgattgcagc taagacaaat gaaagtgaca gtgctggacc agcattttga
    56761 ttggccgcaa cccctgtcac cacaaatatt cccgtaccga tgatcgcacc aattccaagc
    56821 atgatcaaat cagacgtttt tagttctttt ttcatctcac tcgtatgatt gagattgatc
    56881 tctttcttac gaaacaaatc cattgaagtt cctccccatt ttaggttgga aaacagcgat
    56941 taaactgttt tcatataccc taaaaggata ccacctaaaa tgactaaaag gcaaccaaca
    57001 ataacataaa tgagctcttt tttcgttttt ctttcgccaa ggatgaaaat cccacctaaa
    57061 gtagagataa tgatccccat ttgtgaaagt gagaagccaa cagctaaacc aagtgatttg
    57121 actgttagaa gcatgcagat gtttcctaag ccccataata atccacagat catgtttttc
    57181 cacacaaact gatcgacttt aactttacgg aaagcaaaga agcttgcgcc taagatcatt
    57241 ccgatacttt gaggtaagat aattgacatc gcatccaaat tcgcccagtt gacgatgatg
    57301 gtatatacac cataaccaat cgtagagaag atcaatgctc taaaaccctt accaaaatca
    57361 agcattttat tatctgtatc tatttttcct tcgtcatctt gtcgggcagt caaatacgca
    57421 ccgcttacaa gaagagctaa agcaataata ccgtatacat aatctttcgt ttgtgtccat
    57481 tcatggaaga aaacggctcc cgcaatcgta ttcaaaatta attgaaaacc agtagacaat
    57541 ggtagcccta cagaaacacc catgtacttc attccatgga actgtccatt ttgtccaaca
    57601 ctccaagcta agccggataa aaatccgatc aagaaaatcc aaggggtgat tacaggacta
    57661 acaacgaaaa agacaactaa agaaaacaga aatgcaccga tcgtcattcc tagtgtttgt
    57721 tgattggcat cgccaccaat tttaccactt actaaaccaa tactacccca tgccaacata
    57781 gggactaatg ctattaaaat ttccataacc aatctccttt tatttcacat gataagaaac
    57841 ttatcagcga aaacgttaac aacacaagca ctttttttcg tttctaacga ttttctaacg
    57901 tttttcatta taaaaattta agattgggaa aaataaagtc attgttgtcc cttttccttc
    57961 agttgattca gccgtcaaat ggatacctaa tttttcggcc agattttttg ctaaataaag
    58021 tcctaatcct gttgaatgtg ttttgctaag tcgaccattt ctcccagtaa atcccttatc
    58081 aaagatccgt ttcaagtctt ccgctgggat accgatccct gaatctttaa ctgaaaggct
    58141 gactccttgc gcttcctttt ctatgctcac aatgatgttt ccgtgatccg gcgtatattt
    58201 gatggcatta ctaagcaatt ggttgaagat aaaagcgatc catttagcat cggtcaaaac
    58261 agtatgatcc tcaccaacga tctcgtagcg aatatttttt tggataaaat aatttgcctg
    58321 actgcgtatc acaggctgaa tgattccttt tagtccatat tcttggatga ggtagtcccg
    58381 cgagaaactg tcgagtcttg cataatacaa aacttgttct acgtattcat cgatttttga
    58441 taattcattt tctagtaatg tatacttttg atcgtcaata tcgaactcga tcgaacgaac
    58501 tagcaattta gaagcggaaa gtggcacttt gatttcatgg acccatgagt caatataatc
    58561 tttttggtct tgttgattac tgattgctga ttgcattact tcttggtgtt cacggatcag
    58621 ctgattgata tattcttcta ccagtttttc ttcttctgtc ctcccaccac tcaaataatt
    58681 ttgcaaaggg gaagtttttt gtatgtcggc taattttccc caccatcttc tcttgctcaa
    58741 gtaaccaccc agcagataaa aaatcagaaa gacgccctca atcaaagcta aataagcaat
    58801 tgtgctcaaa tcaactttga tgtttggcgc cagccacatc acaaagatcg tcaatgcaat
    58861 aaaaaacagc catcccaaga tcaatgtcca ctgatctttc aaatatttaa aaaaattcat
    58921 cttaaccgct catcctttca gggaacgata tatccctgtc ctacttttgt ttcgatatat
    58981 ccttggatac ctgcctgttc gatttttcgg cgtaaccgat tgatgttgac tgtcaatgta
    59041 ttgtcatcta caaatcgttc gtcatcccac agtgctcgca gcaatttttc ccgacttaag
    59101 atctttccat tgtgcttcat caaaataaat aatagacgat attcattttt gctcaaatca
    59161 atgatctctc cgttgatttc catacttccg ttgtcaacat tcaacgtaat gccattgtgg
    59221 ctcatcattt cactagataa ttctgtgtag ttgtaagaac ggcgaagtaa tgcattgatt
    59281 tttgcaatca gtacatcgat ttggaaatgt tttgtcacaa aatcatctgc ccccatgttc
    59341 atagccatga tcatatccat attcgtattc ctgctggaga taaaaatgat cggtactttc
    59401 gatacttcac gtattttttg acaccaataa tagccatcca aaacgggaag attaatatct
    59461 agtaatacaa gctgtggttc ttctctttca aagtctgaga acacttgatt gaaatcggtc
    59521 gttccaaagg tttcaaattg ccatttctca agttcctcca tgatcaattg tcgaatgatc
    59581 tcttcgtctt cgactaccat gatttttgcc ataaaaaatc cctccatctt tcttcttgct
    59641 actacaatat caaagaagcc cttgtgaaac aagttggctt acctggaaaa tgtcatttta
    59701 gcaaacgtta aaaaaaactg gaaatatgcg atttaatcgc gtttgtctct tccaagcagc
    59761 ttaaatttat tatgttattc ttaataattg gtctattatc tgttattttt ctttcgttgt
    59821 ttttgtcttt taaattttcg ataacaccaa taaccgaaaa gcgttagcac tagcaatata
    59881 cctagaagga gtataagtaa tcgataaaga tggtattttt ttgtctgttc tatctttgaa
    59941 gagacttctt ctgtaaaggg aactcgtctt cctgtcacta gtaatcggtg agtgttcacg
    60001 gtgtaaggtg tacaagtgat aagtgtgact agatcctgct tttctctaat tgctaatgta
    60061 tttgtttttg ttggaaggac aacaattttc tcaacgactt cataagcgag catccgacca
    60121 tacacttcaa gatagaatcg gtcatcttgc tccatttctt caagatccgt aaagagtttt
    60181 ttctcagcaa taccgctatg ggcggtaatc acggaatgtg tactctctcc tccagttgga
    60241 aaagaggtgc cttgcaggac tgtcgctcct ctatctaaca aaagatcatt cgtttcatca
    60301 aataaaggca agctaacatt gattttcgga atatagatgg ctccgatcat atgttgttcg
    60361 taatattctt ttcctggatt ttggacattt ctaaccgctt gctcaaaagg atctttgact
    60421 tgtcccattc ctgggattac tgatgtatga gcaagcgtct gatttttctt ttcatgcact
    60481 gctaattgtt gctcatgttt ttcttcttta tcgcgttcaa gctgcttttg ataattctcg
    60541 atccttcttt gatccaaata attgctgaga gcatctgcta aaaatggata tgtaaaaact
    60601 gcagctccgg caagaaacat cactgccata aataattgta ataaaagact gatttgggtt
    60661 tgaggtctat tacctatttt ctttttcatt ttcttcacct tcttatttaa aaaaactgca
    60721 gcaaccttta taaaaccgat tgctgcagct tatttttgtt gcttatactt cagacttcat
    60781 tttagattta cggtaccagc tgtacgctcc aatcatcaaa cttattccga ttagtaagaa
    60841 tgccaagagc ccgttcccac cagtagcagg aagtgacccg cgtttcatat tcggtactct
    60901 ttctggccct ggattttcta ctcctacgat ctgaatttct tcattatagc ttccataaga
    60961 gatgataaat tcagtaaagg ctgcctcacc tgttggaagt acataacctt ctggcgccat
    61021 ggtctctttc atttgatagg ttccataatc taacccttga acctcaaagt atccatttcc
    61081 atctgcgaca aattctgttg cttgtccgct tgttgcccac tcaattctat ctgctcctga
    61141 ttcataaaca gctaaaggcg actccccttt ataaaatatt gcgtattcag aacggtcttc
    61201 attccacaat tcgaatcttg catctttaag caattcactg cttgatgcat catatttttc
    61261 aaactttctt ccacctgttg tgactttctc tggcggctct actccttctt cataatcaaa
    61321 ttcatcattt cgtccgattt caataaccgc tgtgttgtta tggaaatcat ccgcttctag
    61381 ttctgtggaa accttcaaat tatacgtgat cgttaaatct cctccacgtg catctgctaa
    61441 tctacctaaa gtatctactt tggctactcc attttcttct gtcaaaatcg tcacgacaaa
    61501 cccgttgctt actacttcta ctatataatc ttgtcctttt gttaaaatcg tctcgccggc
    61561 tcgcacttct atttcctgat cataataagt tagaccaact gtaggcgtat ctgtgatttt
    61621 gtaatttttg ataacagcgc ttccgttttc aaggacagaa tcgatgaaat aaggaatagg
    61681 tgctgtgatc gtgtaagaag ccgtttttcc tctttctaga tcaatataag aaatcgtttc
    61741 ttgttctcca gcttcattaa taatcgttac ttgtctaagg tcgctttcct ctacattcat
    61801 ctgtttatct gcttctctga tttcgttttt cggatacaaa tgcacatctg tattgtatgt
    61861 gtctttccat gtagaaccat cccacacgcc atccaccata tcaggcatca tcactggcat
    61921 cataacaacc attggagacg cgattctgga aatatgagct ggcgaataag tttctaagaa
    61981 aagatagact ttatctctag aagaaggtgc ttcttccgtc acttggacgg tagagaatac
    62041 cgcttctcca gcttcattcg ttgtttgttt gtcaatactt gtcagtcgat attttaaaaa
    62101 ccaactttct gtgtgccgtt tttgaatcca ttcaatcgct tcggcagaat taagaccgtc
    62161 ttctcgttcc ggtgttaaag gattatctcg aatcaaatcg taatatactt ccgttacgtc
    62221 aaacaaatca aaatcgactc ctggaatatt ttcttcacca aaatccgtag aaaccaatcc
    62281 gctattcggt cgttcttccg gaacagatga gaaacctttt ttgtgtaatg taatcgtcac
    62341 ttcacttggt ttttgtgcga cttcttcggc tttgactagt tttccgttcc cgaaaatccc
    62401 tattcccgca gtaacgagta acagtacact cattcccgtg acaatcattt ttttattcat
    62461 ttttttctcc ccgttctttt tttattaata aaacagcacc taacaataaa agaattccta
    62521 gtaaagaaat caacgttctt gcttcattcg tttgcgggaa tacggaccat tttcctgatt
    62581 gacctggatt gcttggacca ctcggctctt tcggtttgtc cgttgtttct tttacggtct
    62641 cgttataaac acgtggtgtt gcggattcat aggcagagac tggaactttc ccggattcta
    62701 attcagccat ctcctgtccg ttaactacta catattgtgg ttggcctttt gcatccaccc
    62761 aaaattcagg gatgatgacc tcgattctct tacttgcttc atccatctcg taaccttcca
    62821 caccttttaa ttcttcaaaa taataggtgc cagaaggcaa gaaacgttgt cctgtcgtaa
    62881 caaggccctc tttatccgaa atgaatttgc ttacattttt gtcattcaaa ggatcattgt
    62941 ctgctggttt gatccattga tttttcaagt cattagcagg agccatatct aaataatatt
    63001 tccccccttc tatcatctga tatagagcaa aaacagcacc ttctaatggt tttccttttt
    63061 cagttgttcc tctttgacgt ccatacttga agaagtatgg atctcttaga taaccgacat
    63121 ttttaggata gatatgaatc tcttgcagtt cctcggttga ttctgtcggg tgataaattg
    63181 gcaaaatagc agcaattggg atagctgtct gatcgatatc aacatccaat ccaacttctg
    63241 gatcaatcga ttcttcgaaa atcaaataaa ctgcatcccg atcttggttt ttcttaggtg
    63301 ctttgatacg tgcaatcccg tctcctaatc cgccaaccgt atctttccca gttgttaccg
    63361 aagtccctat ttggacaagc ctttcttctg tgattagctg acggatattg tttctgttcg
    63421 tttcagcgat ttgctggacg aattctttag gagtcatgtt ttcagcagct tttttttcat
    63481 gataataatc ggtcatgtcg taaatggcaa atgtcgctcc atttagtggc accgtctgtg
    63541 aaatgatatc tgctgtttcc cctgcttcct cagagatagc caagccatca ttttcatggt
    63601 attcaaattg atcgttataa tcgatatctc gaatcatccg tttatgcaac acgaattcca
    63661 cgacatcttc ccctgattct tctgccgaca tcgcatgtgg aagaaggact gctgcaagcg
    63721 gtagtaaaac aagtaattga agcatcaaac acaacagctt tttcattacc ttgctccctc
    63781 ctttttagat tgtctgacaa acaaaccata ggctgctcct gcaagcgcca tgaagaatgc
    63841 agcaagcagg atatagaata atcgtccgga tcctcctgta gcaggcaacg gattttcagg
    63901 atcgttcccg acactaagct gtaatctgat tcgatttgtc tccaaaagtt catattctaa
    63961 ctcttgctgt agatcaggcg tctctgcttc ttcgtttgga taatacgaaa tctcaacttt
    64021 tagtgtaccc gcttcttttc ctggaactac ccgatcattt tctatgtcag gttcttctcg
    64081 ataactaatt tctaaaataa agtaacctgg aagttttcta tagctgtcag gtgacttcac
    64141 ttccttgatc cgatagaccc cttccaacaa gtctgaagca ttgaataggg aagaatcgtt
    64201 tggatctggt gccaagcctc cctcgatgat ttcatactct cctgcactat tttgtttctc
    64261 aattgaaaat tctgcgcctt caagacgtcg gctattcata ctgtcaattt tcaaaagttc
    64321 caaatcgatt ggcgctagtt catcttctaa ggttacttgt agtacaccat cgatgatttc
    64381 atagccttcc ggcaagggag cagtttcgtc ttcgatgacc gtatcttcaa tgataaactt
    64441 accttcttca ttcagtgcaa actggaacac ttgatcagat agccgatacc catttggtgc
    64501 gacagattcc gagacctcat attcaccaat agacagatgc agaggttggt cgtaatttaa
    64561 atcgacatac ttttctactc ctacggcacg agaatagaag tatccgatcc caggcaaacg
    64621 tttcgattct tctggttcta acggattacc agtgtatgct cgatacagcg ggaaggaaga
    64681 atcccccact ttcctgatat cgaaacctgc accatctaat gtatggcctt catggtctaa
    64741 ttttctaact cggatctccc gataatcaaa cgtattgtaa gcagtgaatg ctacccataa
    64801 acgatcctct tcatctgttg tatacgtgag atattgccaa ttttcttcac ctgtttgctt
    64861 gagttggata gtccctatag cattatcgta aagtcgcaag atccatgtgt cattttcatc
    64921 aggttctttg aaaccttctg ggttctggct ctcaatgatt ttgtattctg catagttggt
    64981 agtttcttca ctatccttat aaacaaatga atctggctct ccgattggat gaataacttt
    65041 ctcaccatcc acgattacat atttcccgtc ttcatctact gaatagaacg tgagtctccc
    65101 tttctcttcc tctacttcgt tcacaccaga aagccctttc gctactggat atccgatttc
    65161 cagtccgtta ccatctgttt cataaagttc aaactctgcg ccattgattg gcatattact
    65221 gccttcaatt agtttattga tattcatgtg gattggcttg aattcatttc gcatttccag
    65281 tttgacatac aactcatcat actctgtgcc ttctatgtta ggctcttgta caacagaaag
    65341 cttgtgatat tctccttcat aataggaatt cggatcttta ccttccggtc cgccgactct
    65401 cgaaccagat gtatattcat ctacaagctc gtagtgacct aacatctcat cttcgttggc
    65461 tgcatatttt ttgatttgga attgatacgt ctcatctact aactgataac gtggtggtcc
    65521 agcgatctct ctgatccaaa atatgtcgct gactgctcca gtttcatctc ctaaaatcgg
    65581 catcttcgtt tcaaagatcg ctattccgtc cgtggtagtt ttacttgttt cgattggttc
    65641 ggcttcccca ctctctggat tttggtcata taatgcaaat tcgactccag ccaacggctc
    65701 gccattttga cccttcttgc tgacttggaa attacggcct ttatgttcgt aacgaatgga
    65761 agaagatggg aaatacatcc gtccagtagt gatatcattc tcataatcct ccaggttctg
    65821 aatataggcc atattgttca ctgtgcaaaa atttccgtct tgagctcccg catcaagttt
    65881 tacttggtac ttgatcctga ccatttcccc ttcacctaaa gaaatcggag aaaatttata
    65941 agcttggttt tcccgtccga catacgttgt cggagtcgcc actacttctg gtggggcttg
    66001 tccatgacgt tcttcatccc atatttctgg ctcttggtac ttcatgccgt tttctcctgg
    66061 atctagatgg taaaactgaa tatctgccga tctgccagct ccaaatggtg agacattaaa
    66121 accagtttca tcataaagtg tggcttgctg gatcgttctc ttgaaggtag aagagatatc
    66181 ctccaaggct gtaacaatgt cattcttgtt gttcgcattg taatatcgcg gtgttacgcc
    66241 atcttcttct aaatcagcaa tatttttcaa tacatttcgt ccaatagcat ctagtcgttg
    66301 tctcccgcta acgtttccat cgattcctaa accaatggag aagatacttg gcgggttctc
    66361 ttgatacttg tttttcagcc aatgatgata agcaactgtg ttgatcgcag atgacttttc
    66421 ttgcgaagta ggactgccat tcgtattgtt attagaagaa ccatcaccaa cccagtgagt
    66481 cgctttatta tctccttctt ttacctctcc ataacgatag tgtacattta cttcatcttc
    66541 tggacggtta aagtcagatg cataggtaac tggatgagta aaccctgcat tagaagtatt
    66601 cccagaaaac tcctcaaaat ttctgaacaa aacgtcatta tcttcagcaa tcttatcttc
    66661 catcacagtc cagttgctcc aagctccatt agtgctcgta cgataacttg actgaatcgg
    66721 tgcataactg aaggtcggtg tcccatctcc cacaacgatt aggatttttt ctggatttct
    66781 attttctccg ccattgtctt tatacaatgt ttcatagcca tttttaagcc ctagtgtaag
    66841 cggagttcct ccgattggtg tacgatttaa tgctgtattc tcacttcccg tcaaacgatt
    66901 gatatcattt gtcaatggaa agatgtccga actgatttgc tcatggttat tgatagctgt
    66961 actattatgg taaaaattca ccataccgat tcgaatatcc agactcgggt cagagagcag
    67021 atctttactc atttcgttta ctgcctcaat caacgcagca tttttagttt gactattggt
    67081 cccagcggtt aattcactca tactcgctga cttatctaga acaaaaacga tatcgattgg
    67141 actgatttcc tttttctcgc ccccgatgac atctagatag acattgtaaa gggttgttgc
    67201 atcttcagga tgtagatcag atgctgtgct gcttggcaga acaggttcta cccatttttt
    67261 gatgtacgcc ccgttataat ccaagtaact gttttcaaaa ttccgttcat ttccccaaag
    67321 ctgaacggtt tgagctggaa cgtttctatc ttcttcgcct gcagttgatc cattattagt
    67381 agcatagtcg taatttcgcc agttcgctcc cccgtttgta taatcactat catcgatcaa
    67441 gttctctccg tcatatggcg agcctttgtc tccttgatag cgttcattgc tttgtgtcca
    67501 atttcctaac acttttgtat agtcattcgt tgtaaacttc atctattctt tcatcaacca
    67561 ccacttgaag aggtagttac ccttcgttca catcggggat cttttctgtt tcaaaaatca
    67621 atgtgccggt ttctgcttct tttgaataaa cttttccgac ataccattct tgaccatcga
    67681 tcgtctcgac ttttaggtct tctccatctt catcatagga ggatagacct gttccacgaa
    67741 cgttttttac ggtaccaatc ccggcggctg ccgcatcgat tgctaaacgt attctacctt
    67801 cattggcact ttcctttttt tcaaaagcca gatgccattc aagggtttct tctttttcaa
    67861 tatacttccc ttcaattttt gcatagtcct catctaagaa tacctcatcc tcctttgttt
    67921 ctgttgactc agcagctaca tccagggtcg tcatatgata gactgactgg aaatatggtc
    67981 caaatagcaa actgacagtt actaactgca aaagcttcaa ttttaaccct ttcacatcct
    68041 tatactcctt tcaaaaatat ttgtcttctt tcacaacaat caacaaaaca atgcccatct
    68101 aattataatt taatttaatt ttaattttaa atcaaatgat atccttttta gttaaaaaac
    68161 accaattata caacatttat tattaaaatt aaattataaa attttataac gttctcattt
    68221 aacaaaactt aagttattaa gacaaatgaa taaacaacta cgctttcctc gaaacaaaaa
    68281 aataaagcac aaatgcgcat ttacgcactc atgctttatt cgtacaatta attcagataa
    68341 cggcagcgca taggatgcca ataacacttc ctaaaatagc tcctcctaaa atgtcagtag
    68401 gataatgtaa aagtaaaaaa atcctcgaat aagcgatcaa acaagcaaat aaaaaggcta
    68461 atattcctgc aactggactt aattcgaaca acgcagctac tgataaaaag gctagcgctg
    68521 tatgtcctga aggaaaagaa gaagtcttcg gtttacttgt gtaaaggaca agccgacgat
    68581 ttttttcata aggtcttttc cgtcttgtcg tttttttgat aaaaagcaaa ccaacaaaaa
    68641 aatagatcaa actgccgata agaatggcta gaccatattc tctagtatca ggtatcaaga
    68701 ctaaaacagc agcaaggagc aaccaaataa aaccaccatt agagatatta ctgataaatt
    68761 tcaaaaaatt gatttttcga ctatccgttt tccgttgctt ggcgaacttg ttgataatac
    68821 tatcatcgat tttagcaatc aaacgcaaca tgttattcct cctttttaag aaccttttct
    68881 tgcgtacgat ggataaaaag caggacttga aaataaaaca agaaactgaa acctaataaa
    68941 gcaaaataga ttggtcctgc aaaccagaat gcgacaagaa ggatcaacgt gcctgccaaa
    69001 tagaaaagcg cgcttttgaa atcattaaaa aacaagaaaa atgcagtaat ccaagaagct
    69061 tctttttgtt ccagttgaag caagattttg taactaaaga gaagcgcgct taatagaagc
    69121 aaaaacaacg tagtatacat caatgtatag ccaattcccc caccccaata gcggaaaatc
    69181 tgataatcga tcaatagaag aagaaaataa acacttgcta aactatcttg ctttccataa
    69241 aaagagaagt tctcacgaaa ctttttccag aatagtgaac cgagcttttt ctcttcattt
    69301 tttttgtaat gataaatcat atacagaact gttcgacttg cagttcctaa tgtgaaaaca
    69361 ggcaagacgc acaggaacca tagtagctgt aaatggataa gacgtggaat ccattcaatg
    69421 atttctaaga aataatcatt ggctttttta ccaatcgatc gattcatcat ccttttgaac
    69481 ctcctgtcaa atccatccct tcaatgaaat aacgttgtgc aaaaaagaac agcaaaatcg
    69541 tcgggatcaa gacaagtgtt gctcctgcca tcagataatt ccattgtgtc gttgcttggt
    69601 tctgaaaaac ttgcaagcca atctgtaacg tgtatttttc ttgatcttgg atatataaca
    69661 gaggacctaa gaaatcattc caagctgcgt tgaaggaatt gatcgcaatg gtaatcaagg
    69721 caggtttcgt caatggaagc atcaaatgac tccaaatata caaatgattc gctccgtcga
    69781 tttcagcagc ttcgatcaat tcattattga tcgataagta aaattgacgc atcagaaata
    69841 tattgaacgc attgccgaag aacgatggaa cgatcagggg caaataagta cctacccagc
    69901 cgatcttgga gaataataca tattgaggga tcatcgttac aaaccccggg atcatcatcg
    69961 tagaaagaac caaagcaaac atcagctttt tcccaggaaa atcaagcttc gcaaatccat
    70021 aagcaataaa agaatttgaa aggacattac cgatcactac tagcacagtg atgaataatg
    70081 tatttcttgc atagcgccaa aaaggaaagg cggcaatcgt atccagatag ttttcccata
    70141 cgattttttc tgggaaaaag gtcggaggat aacgaacgat ttcttccatt ggtttcaatg
    70201 aagtaaacac catccaaagc aatggaatga tcaaaatgat tcctattact gtcatgagga
    70261 cataacttag tatttttttt gtttgccgat tcacactggt ctttttgaaa taatccatca
    70321 tttgccgtca cctccagaat aatagaccca cttaggtgca agcttcaaat tgacaaacgt
    70381 cagaaccaac acgatcagaa acaggatcat tgacatagcc atcgcataac ccatatcaaa
    70441 agctacgaac gccttgttcc acatatgcag attataaaaa agcaaagaat ttgcaggtcc
    70501 gcctgttcca tttttcgtca tgacataagc ttcttgaaaa atttggaaag aaccgatcgt
    70561 agaggtgatc acatcgtaaa aaataatagg agtgattaat ggcaaagtaa tacttttgaa
    70621 ctttccccaa acgcctgctc catcgatttc tgctgattca tataaagatc taggaacatt
    70681 ttgtaatgta gctaagtaaa gtagcattgc tcctccagaa ctccatattt tcatcaaaat
    70741 caacgcaggt ttcgtccatt gtggatcaaa cagccaagct ggtccaggga tatggaacca
    70801 gcccagaaat gtgttgatca atcctgcaga tggagaaagc agctgcatcc ataagatgta
    70861 gactgctact cctgataaga ctgccggtaa atagaaagct gtacggaata cactgattcc
    70921 tttgattttt tgattgagta ctgtggctaa aaacacactg aaaatcgtcg tcagcggtac
    70981 attgaagatg acgaaataaa cggtgttgta taacgatttc caaaataaat catcgtgaac
    71041 gaacattctt ttgaaatttg ctagaccaat gaaattcatc ttggatgtca aattataatc
    71101 ggtgaaacta ccaataactg aaaaaagcat aggccctagc ataaatacca agaacccgat
    71161 aataaaagtc gagataaata aataggccca tcttgcttct tttttctttc ggatagataa
    71221 acgcttcaaa ttttcttgcc tcctctgtac ctagacagtc aaaaatggat tattgatttt
    71281 gcttgactaa gttttctact gctttttgtg catctgccaa tccttctttt ggtgattttg
    71341 ttcctaaaag aatctggtca atctgttcat tcactaatgt cgtgtaatcc ggagcatcta
    71401 aaggaactgg tgtgatcacc gtatttttaa agttttcgtc cgccatttga tagatcattt
    71461 ttcctttatc cgttaggttg tcattattca ctaaattctc attggctgtc ttgctcgcca
    71521 tgatatcaaa acttttttcg ccgaattttt cttgtacttc tggagaagaa agatatttga
    71581 tgaattcata agaggcctca ggatcttttg ctccgtatgg tacttccaag acgaatccgc
    71641 caccccacga ccaatggcct gaaccttctt ctttttctgg gagctgcatc acgccaaaat
    71701 caaaatcatc cggtgcattt tccatcaaac tagagtaata attgatattt tgggcacgca
    71761 tggctactaa tccggaaata aatggatcag atacaccaga cccaaattcg gcttctaatt
    71821 tattgatcgt atttttccca taataatctt gccagtcttg gatccactcc aaggcttcca
    71881 ctttattttt agtatcaatc ttgacttttt catctttgtc aaaccaacta gtcccgttat
    71941 ctgcgtttag cgcccataca tcagccccta aattccataa tggataaaaa ccgatgcgtg
    72001 taaattcttt tccttctttt ttatctagtt tacgtgctgt ttcttctaat tcatcccaag
    72061 ttgtcggtag atcttgttca ctgattccag cttctttaaa taacttttta ttataaaaaa
    72121 tgacttgtgt atctgtattg aatgggatcg cataaggatc accttcatat tctactgtat
    72181 cccaaagctg cggataaaaa tccttagaag tgtctttttc tacatatttg gagagattag
    72241 ttgcttgctg tgcttctgct ctttgggcaa cggaatttat gtcctgtaca ataacatcgg
    72301 gtgcatttcc agctgttatt gcagataaag atttagtcca gatgtcaccc catggctgat
    72361 acttataatt tacatggatc tcgttttgtg attgattgaa atcctcaatg atttcttcga
    72421 tagcttcttt tcgtgcaccg gatccccaaa aggaccagaa atcaatattt tttcttccat
    72481 cacttgtttt ttcagaagaa tttgctgcac ttgaactggc atcgcttgca ttacttgatc
    72541 cgcatcctcc taataaaaac aatgctgaac ttgccagcaa ccctgtaaac aataattttt
    72601 tcatatttta cctccaaatt ttaatgtaac cgatgccggt tttaatataa cgatatcatt
    72661 ttgttctgaa aataacaatt tataaggtat gattctaaaa aaattattaa tgataccaat
    72721 actttatata attcgcgagc gctttctttg aattttttaa tctttcgtag cagaatgaga
    72781 atgtattaaa aatagattag gaggaatttt gatgtttaga caccagaaag aattgcagtt
    72841 tgaagcaaaa ccagatcgtc cgaatccatt aatcgcgaaa tatctgcagg agctgatcgg
    72901 cggccaatat ggcgagatga gtgtagctat gcagtacctg ttccaaggct ggagctgccg
    72961 aggagaagaa aaatataaag atatgctgat ggacattgca acagaagaaa tcggccacgt
    73021 ggaaatgttg gcgacaatgg ttgctcgttt attagagggt gcgcctgttg aagatcaaga
    73081 agcagcgatg caaaaagatc caacaatcgg tgccattatc tctggaatga atccacagca
    73141 cgcgatcgta gctggcttag gacctcgtcc tgctgacagc gtgggcaatc catggagcgg
    73201 tgcctatatc attgcgagtg gcaacttgtt agcagacttt agagctaatt taaatgccga
    73261 atcacaagga agacttcaag tagcacgtat ttacgaaatg atcgatgatc gtggcgtaaa
    73321 agatatgctg tctgttctcc ttgcaagaga tagctatcat caaaatctat gggaatgtgc
    73381 agtgaaagaa ttagaagaaa aagaaggttc aatcttagtc ccaagtactt tcccgcgtga
    73441 caaagaacga aaagacattg cttatgactt ctataacttc tcagagggag accaaagtag
    73501 tgaaggttct tgggctagtg gcaaagcact ggatggcgaa ggcgaatatc aatggttgaa
    73561 agaacctaag atcgaaggcg ctgcaccaaa attagaacca gtaacaccaa aaatgtatgg
    73621 gacacctcca ttcaagaaat aaatatctac ccgtagaaac acccgttttt tgttccacac
    73681 gctttgtgag caaaactgac taaagtcatt aatcataacc acccttcaaa agggtggttt
    73741 tctctagagc tataagctca aatcaccggc cagcgcctaa agacgctggc tttcatattt
    73801 tatgttcaag ccatattgcc tttgccagtt ttgcccacct cttaaaaggt ttatgtacta
    73861 ctccttagcc cttaaaagga tcgtcttact ctcgtacact cagcttatct aacgcactat
    73921 catgtttttc ttgttcttga atgtactttt tgatggtcgc ttcattttgt cctacttttg
    73981 tcacatagta tccttccacc caaaagtgtc gatacccaaa tttatatttt agatttgcac
    74041 aatctcttga tgatctcctg aatattggct cgatattgat tataaattat ttttcttcta
    74101 tactttggtg tgaatacaat gtggtattta cacatctact ttgtacgggc taaactattt
    74161 ccctttattg ctccacccgc atagcaagtg gttttgtatt tcaatcgctc ggcgcgctca
    74221 attaggtcta aagacaataa atctaaaaac ccgctgcttc actgacagaa acaacgggtt
    74281 ttcagaaaaa aatgaaatga aaaagatctc ttacggcaat ctattttatt tttttgattt
    74341 tttataaatg gaaaatgctt caagaagtcc aagaaataaa gccgtataaa aacaagaacc
    74401 tatgaaatct ttatttatta gatattcaac agaaatcccg ataacactag ccaacaatat
    74461 atttatcaga agtgtaaaat aaggatgctt tttatagaat agaactagtg ttgttttcat
    74521 agactctcct ttcttcatat ttccaattaa tcacaaattc acggcattac tagaaaaatt
    74581 aaaggggcgc agaagtggaa aaatactctt cgactttccc tacaaaccag gccatcttgt
    74641 gtttaataac tataccaaat ctaaggtacc tctaaatcta aattccattt gtggcggtga
    74701 cctccaattt ttaactcttc tatctcccat ccagtataca taaccttgat acttcgacca
    74761 cttatatatc gaacacacaa atacctatcc attgcaggag tactacctaa cttagttgct
    74821 acttgcatct aaataacagc tgaaaagata ggacttactc ttagtaaagt atctgaacta
    74881 ttaattttta aactatcatt tttatcctca actacatgca catctgttgc aacttcactt
    74941 tctgtctcat ccagataaat gattaaggaa tcgggaattg caatatcttc agctgacgct
    75001 ggaatagttg agctaaatta gtcatcatat ctttattata aaataaccaa cagcaaaaaa
    75061 tacaatgaaa aacaaacttg gaactaatgt atcattaata aatgttgaaa aattcagcaa
    75121 ctcattactg tatgatttta gcagcccaac caacatatac cctataaaag ctaataagat
    75181 ggttaggaat cctttagaat ttttactcat tcatagacac ttccttaaat aacttttatt
    75241 atagaaggta ttgtaaataa taatattgac aaaaagtgac tcaaaataaa aaaaaactta
    75301 cattatactg gaatgaactg tattgatagt gtacctaaaa gctctactga cataagatcg
    75361 tgtaatcggt aaagtaattt tattaattat acgggatgta atcaattaga gaataaacta
    75421 atcataaaag gtacttttac attcataatt gtcgctttga gattctactt tggttcacta
    75481 tctgacccaa ttgcacattt tcgatcatta caagtattgg tgtcgttaga acaactaaat
    75541 aaaaactagc ggtagatttt tcagaatcta tgctaatttc tgtatggatg ttccagtgat
    75601 ggcaaatttc tcttttcatt gtttttcttg tcgcatgata tgcctttttg tgttattcag
    75661 ttaaactata gaaattcttt cctagacaga tcttgatccc aaattttacg tttttgagca
    75721 tcgatatagt ttaaaatgac attactcata tctaaagagt ttagattttt taggactaaa
    75781 actgtcagtt gttctttttc ttctttctgt taaagtattg tcgcgacttt tcgtatacgt
    75841 taagatatgt cgtgaaaaaa caagttttgt gacacaaaaa aacgaatgac ttgaggaaat
    75901 cacctcaatc attcgtttaa aatgctatat attctttagt ttaagatacg gaaattaatg
    75961 ccatcgacca cactagtaga atgaacgaca tttacttggc ctttttttaa tttcgttatg
    76021 tttagcatat aaaaatatta tagagtttac ttacaatgct taaaacatat actgtataat
    76081 ctgatcaatt ttagccatgt cttgcaatgg taagttttct atttttttga gttttcgttc
    76141 cttaaaatca agagatttta attgtgtaat aattacttgt ccttttatat ctagctcttc
    76201 aggtaatgag taacgtgtcg gtaaattctt tatagtggaa gtaattggac atatgaccga
    76261 aaacattgtt ttacggttaa attcataacg agagacgact agtcctggtc gtcttttttg
    76321 aatttctttt cctacggagg gatcaaaatc aatccataca atatcacctt ttttaggaat
    76381 ataaattctt tcttctgaca ctataaaatt tctctccctt caggagttaa atcttcccat
    76441 tcgtctttct cataatactc ggcctcttcc ccaccactaa atggatcttc aatttttgga
    76501 actaacgtaa ttgttccatc atcagaatac acaacgatat attcttggtt ttctgaaggt
    76561 ttctttccgt tatcagaagg taaagttacc actacagaac ttccttgtaa tctagatttt
    76621 gtaacaagca ttatcatcac tcccttaata aaagtatact atataacact aagtaacgca
    76681 aaattcccct ttgtaaacta tctagaaaat tgttttgttt aaagtatatc ttattggata
    76741 taaatagaaa taaattgtag ccagttcatt ttttctttaa ctaaaaaaat aatccaagaa
    76801 acattgaacc tatggatcca aaagctaccc aaatactata gctaaccccc cgctaccttc
    76861 aattttgcag ataaaacgct ttgggagaaa atttcaaaga caacaggcca tcctatcatg
    76921 cccgattata aacaaaaagc tggctattcc ttttgctctg acaaatttca attgggaaag
    76981 ttcacgaaac tagcaggtga agaagtttca actgttcgga tcaaagaatg cccgcttcaa
    77041 atagaaacat tggttcaacg aatttcaact agacaagact ttgctattgt agaacgtgag
    77101 atcgtagcta tttttgtaga agaagggatt ttacatgatc caactcatat caatgtggat
    77161 aaatggcaac ctcttatcta taaattcaga gaatatacaa ctgccaacca gtcgttaact
    77221 ttgaatttta gattccaaga attcaaagag tcataatgat aaacatcgtt aggtataaat
    77281 aaaaaagact cgcagcacga gtaaaaaaca aatagaagct atacattaga aaggtcgact
    77341 gtgaccctat agatgcagta tatgcagctt atgagcattt cttctgttct ctttgttttt
    77401 gggatctgtg ctgaagtctt tttcgttttt tgccgctctt tctttgaaaa atcgattatg
    77461 ttataccttc tccattacta attcaggcat ctgctgagta atgatttttc gcgcaaaaga
    77521 aatatctgtt acccaaggtt cgatttgttc ttcagtcaag acaagcggca ttcggtcatg
    77581 gattggtgcg actgtgcggt taggttcagt agtcattatg attgattctg ccattttttc
    77641 atcctgatgg ctacgataaa aaccgccaat atacactatt ttttccttat ttgaaaacat
    77701 aaatttgtct ttttcttcat tccactcatt gggaaaacac aacgattttg caaaaatggt
    77761 tgatgaaagg tctttttttc ttctactgtc tctgcacggg cattaatcat caattgtcct
    77821 tttttaaatc cggtaaatcc ccacttcatg atttccggag tgaggatgtt ttcttcctct
    77881 tttcttaacg tcacaacaag atttgacgga aaaacttctc cagctgctaa ttctgctgcc
    77941 tgcttcggtt gtttcgtctg ggcttctcga taataattct gaaggagctc tgactctaga
    78001 tcaaaaaaat aacgaccaca catcctaatc cctcccaatc tttttttcta tcatacactg
    78061 caacaagaag ttcgcaccaa caaaacactt tcaatttttg tagaactaaa aaagttgtga
    78121 caagtgacaa actctccagt gaatggtatt ctcctgccaa ctcctcggtc acaagtcaca
    78181 atattcaaca aacatgagaa gctgcttttt gaaattgttc cttgtgactc ggagtgaaac
    78241 ggcaggctta cgacctctgg gtaaacggtg ttcaaaagcc agtttctcgg tattaagcca
    78301 aatttatgca aaaatgtaga aagctatttt cacaaaattt ttcttaatac tcgaaactaa
    78361 gcgacttttt cacaacctct tccttaaacg gtgttcaaaa gcttgcatct gcggtaataa
    78421 gcccaaccaa acgaaaaata tgagcagcta tttttatttg gctgttctta ttacttgatg
    78481 cagggcagct ttttcacaac ctctccacta aacgatgttc aatcagctaa ccttcggtat
    78541 tagctcaaaa aacggcaaaa tatgaggaac tattttgccg tttgtttctc taatactcag
    78601 gtcaaagcgc tgatttcaca acctctaata cacggtgttc cagaagtagc ttcttcgaaa
    78661 aataagccga aatttcacaa aaatttgaga agcaattttc gtaaattcct tcttatttct
    78721 tgaagctgac cacttctgtc acaacctcta attattaaag aaccttttgc gaagttaaca
    78781 atctttcttt gaccaattga aaattctgcc taagtagtga tagatcctgt gtgactttca
    78841 acaataagat acttccctgg atttcagcaa tcaacgcttt ggcttgacgg tctgcttctt
    78901 catcggacag tttttcttca gaaagtgcca ggatattttg tttcgtatac ttgacccatt
    78961 gattgactaa ttctagtagc aacagacggt attcttcatc cactgtactc aactcaataa
    79021 tcaaattacc tacaggacag ccatgataag tgatctgtgt ctcatgatca gcgaaaatcc
    79081 agtccaacat ttcttctaat gcttcttctg gctgttttcc agcatttaag atgtcttcga
    79141 acaattctgt ctgccatacg tccatatgcg catggatcac cgctagacaa acttcttttt
    79201 ttgaagaaaa gtaataataa aattgacctt ttcctgtatc agaagctgct agaatatctc
    79261 ggattgacgt ttcatgatag ccttttttat aaataagatc tttggtcgct tccaagatct
    79321 tttcctttgt tttcaatgat attctccttt ttcatttctc atagtcctat attatacagt
    79381 aaattcatca ttttttcttc ttaatcgttt aaaaaagact gtgccaaatt atctgacaca
    79441 gccctcacta taaaactgtt ctcatatagc tagatgttca ttgattcaag aactgcgagg
    79501 acaaaagcaa ttcctatctt atgatagttg ctctaatact tcctctgttg tcatcacttg
    79561 atctgcaata aagccaaagt tcgtcaacgc tgcatccatt gcttcttggc caggagcacc
    79621 aattgcatct gtcgctacca caacattgaa tccactctct accaattcac gcatatggga
    79681 atcgctacac aagtttccgt tcattccacc aagaattact gtgtcgattc cattttttct
    79741 caattggagc gccaaatcat tgctttctgg tccaaagatt ttatgaggag agctgatgat
    79801 cgtattttca tccaaataag gtttcaattc ttcgataaaa tcggctcctg aaccttcttc
    79861 cactgattca tattgacttt ttctagcaaa catctgctgc tcaagcatca tatgttctcc
    79921 tgcaccgcca aattgccatt tatggtcatg tgggtaaaaa taatgaggag aaataaagag
    79981 tttgtatcct ttttcttttg cttgttttac catttcaatc atattttcga tcgtattgta
    80041 tttttctaag atatcttttg tcaaaccaaa gccaccgcct gctggtttca agaactcgac
    80101 ttgcgggtca gtgagaacta ctgctgtatt tttattattg aacatggtgg attctccatt
    80161 cgttatttat tttaatacat catttagagc ttcactcatt gtcggatgag aatagatttg
    80221 atctctcaat aacgtataag gaagttttcc attcatagct agcgaaatca agttgatgac
    80281 ttcatgagaa tcttccgcat agatacttgc ccctagaatc aagtcagttt cagggtcgac
    80341 taaaactttg aatacacctt taggatcttc taatacttgt gctttaggga caccgcttgt
    80401 catatacttg aataatttgt aattgacgcc ttgtgctttg gcttgttttt ctgttaaacc
    80461 tacattggat aaagtcggag tgataaatac actgtaaggc acagctttcc ggttattcgt
    80521 tgttcgttta ttctcgccct tcaactgatc cataatgatt cgataatcat ctagagagat
    80581 ataagtgaac tgcaatccgc ctttgacgtc tccaatcgcc caaatgttgt ctgcatctgt
    80641 acgaaggtat tcatccacag cgattgctcc gcgatctgtt agtttaacat ctgtattttc
    80701 taatccaagt gatgctgtac ttggttttct tccagttgca gccaaaactt ttgacgcttg
    80761 gattgttact tcttggccat cttctgtaaa ggtgacggca gctgttgatt cttggtctgc
    80821 tacttgatct acagatacac ctagatggaa ttcgattccc gcatttgtca tgtcttctaa
    80881 aatcatttgc gcgatatctt catcttcacg tggaagaaat tcagaatggg catcaagaac
    80941 gacaacttta gatccgtatt cattgaacat tgatgcaaat tccaagccaa tatatccagc
    81001 cccgatgatc actaattttt ccggtaattg ttcctgatcc atcgcttgcg tagaatcaat
    81061 caagtagcga cttgtattca atcctttgat tggtaaaatg attggttcag aaccagtatt
    81121 gatgaaaatc cgttcgcctt caacaatcac tttttcacca ttattcgtca cttcgatttg
    81181 atggttagaa agaaaacgtg ctgtaccgtc catcactgtc ccagttgcct catcgctgat
    81241 catatgataa tttttggcgc gaagcatgcc cgtcaatttt tctttccgag caacagcctc
    81301 tgtaaagtcg attcctcttt ctccattgaa aatcaatgat ttagaaggaa tacagccgat
    81361 gttgatacat gttccgccat acatacgtgt tgacttttca acgactaaaa ccgattcacc
    81421 ttttgaagct aacgccttcg ctaaagtctt accgcccttt ccaaaaccga tcacaatatt
    81481 ttgatatttt tccatcattt ttccctcgct tcttttttac ctaccgattg gtacaaaaat
    81541 atgataaccg ataattgtct attctccaaa tcatctgctt tatttgtcaa aaaaaaccag
    81601 acaaaaagcg gtcctttcac gtttttagtc tggttcgatt tcctttattc ttctaaacaa
    81661 tcgttacttc tacatcgata tttcctctag ttgctttgga gtaagggcag aattcatgcg
    81721 catcttctgc aattttttgg gcttcttctt cgctgatgcc atcgatatgc acttcgaata
    81781 ctacaccgat ctgatagccg ccatcatcta aattataaag agagacacgt gcttttactg
    81841 tggactctgc tgtcattcct gcttctttga tcatatgttg taccgcccca ttgaaacaag
    81901 aagcataacc tgctgcaaat aattgttctg gatttgttcc ttctgcatgg attcctggag
    81961 gagtgatttt catatgcatc gagccatttg gttcctcgac ttctccattg cgcccgccat
    82021 ggttgatcat tgctgtttcg tatgcttttt tcattgtact gctcctttcg attgaccatt
    82081 tgctacttgg ctataattat agtgtatgac aagtaaggcg ctttctacaa aaattctgct
    82141 tattcgaata ccagaatgcc gtcttctact atttttccaa aaaacaaaaa aatactactc
    82201 gtgaacaaca gcgtcatatt tgttccaaaa taaatagcaa tcttttctac ataatctttt
    82261 atatgattga ttttaagata catatatacc agaaagttga ccccataaac caatactgtt
    82321 aaaaaaataa ccatattcgt taccattttt tcctcctttt gctggtctcc ctaccagcac
    82381 tcgatttaac cataccactt tttttgccgt ccaagcaact agcctttcaa aaagactggt
    82441 ttattctgct gttaatgatt caagatcaga aaaatgtccg aataattttg ctaattttac
    82501 taacgccaac ttgttctttc cgaattcatc attttctatc tgtaatacta gtaacggctc
    82561 atgtaagctt aaacggatca aaaaccagcc gtttccgtat ggctcttcta gatcatatcg
    82621 aataccttct tcattttccg ggtcgaagtt catccctttt tcttcttcca acagtcgctt
    82681 catttcttct aatatcttgt ttccttgttc gcgtggttca tcgctgaaca attttaatcg
    82741 gatttcttgt acttctacgg gctgtttcaa ctctttgatt tgttcatcta atgtgatacc
    82801 ttttcttttt aattctggca aaagcatcag gatctttgcg atgacatatg caccatcatc
    82861 cagaaaatag ttttccttga atgcagcgtg tccgcttgtt tcgatggcta gctgtgtatc
    82921 tttcccaaga cggttaagtt ctaatgcttt attgattaca tttcgatagc cggaaatata
    82981 acgaacttgg atgcctcctt tttcttcaat gaatctttgt agatgagaag aagtagggga
    83041 attcgtcacg attcttgttc ctggatgctc ttttaatacg attgtactta atactgcgat
    83101 caaattattt cgattgatca ctgttccaga agcactgaca actgcagaac gatccacatc
    83161 tgtatcgaaa atgatcccaa gatctgcttc atttgctaaa acagcctgct tgatactttc
    83221 catcgcttct ttattatcag gatttgggat atgattagga aatcggccat ctggttccaa
    83281 aaattgggaa cctgttgaat ccgcacctaa gctattcaat actttttcag caaagaatcc
    83341 accagcacca tttccggcat caacaatgat tttccaacca tttagtggtt tgctttctag
    83401 tgttccaatc ccctttttaa tttttgtgac taaatcttgc gcataaggtg tcaaaaggtc
    83461 tgctttttct acgcttccag tttgttcgct ttttattttt tgctgctgtg ataggataaa
    83521 agcaatatct tctttttctg ctcctccttc tgaggtaaag aattttattc cattataata
    83581 atagggaaga tggctagcag tcagcataac cgcagcatcg cacgagaact gttcaaattg
    83641 agtggacata aacatagcag gcgtagtagc taattcgaaa tcgatgacat gtatcccttg
    83701 ttctttcaga ctttggatca acgcctcttt cagtgctggt ccgcttatcc tactgtcatg
    83761 accaatccca atcgtccatt ttttatttgg atcggttgat ttcttctttt tctttatcca
    83821 gtttgctagt ccccagccga tcttttttac catgtctgtc gtcaagttta cttcatatcc
    83881 ttcaactggt aatgcgattc ctcgaatatc cgatccattt tgcagcgctt tcatatcttt
    83941 catataaaag tcctcctcat ttattccctc attttttcca gcttttctgc aaatcgctgt
    84001 gcttcttctt ctgagcggca aataataatg aatgtatcta caccggccat cgttccgaca
    84061 acttcagggt aagccacttc atctagccaa ttcgttacca catcggcacc atttcgttca
    84121 gtcaatacga taaccatgaa ctgaacagac tggatacgca aaacctcgcg tctaattgct
    84181 gtacgcaaac gttcttcatt taaagaaaca gatggctggt taaataatgt atagcgtact
    84241 attttgtttt cattttgact ttttactaac ttcatttctc gaatgtctcg agaaatcgtt
    84301 gcttgagtca catcggcgcc tgcttcatgc agccgcgcaa gcagctcttc ctgtgtccca
    84361 ataggttgtt ctgtaatgat ctggcggatc agtgcttgtc gctgtttctt tttcatatta
    84421 gacacctctc aatgttgatt atagcaaaag ataagtaata tttcttcata ttttggtatt
    84481 ttttactttt attttttgtt ttcattcagg ttgctaacct ttttctattt taacacgcaa
    84541 aatcgtcttc attttttcag gtgctgattt tcttggatcg ctgatgtaaa tctctttgtg
    84601 ttctttagaa gctctttcat agccttcttt tgcgatgaat gcttctaatt tctcaaacgt
    84661 tgctggttct tcggcatagg gcccgacgtg taagatttgg gcacaaagac cttcttccat
    84721 ctttttgaat actacttgtt ctttcaagtc ttccggaagt ttgctagaac gctgaatggc
    84781 ttcttgtgct atcgcttctg taacaaagtc aggctgtcgg atcatcaatt gataagaaaa
    84841 atgttctttt ttcatcactg gttcatgcaa atacttttct tgcagtcccc attgtccttc
    84901 cagtggatag acagtataca tctgataatc aggaatcagc caattttttt taggcgacat
    84961 gcgtattgca tagctgactg catatagaca ggctactctt cgtttaaagt cttcctgatt
    85021 cgggtcgccg atccctctga tgctaaagaa tgatttttta ggaacctcta gtatttgcgg
    85081 gctttttttc atactatagc tcttgtcttt acgccattca attttttcca tttttcttcc
    85141 tccgcgaaat tccatttagt tatttattat catacctctt tttgagtgac ttggctaatc
    85201 gtgttgacac tatttttcag tttgtgctag aataagtgaa gtaaataaat cgtacagata
    85261 acacgtttcg gcgtgtcgag agagaggcgg tttctatttt tataatagaa atcactctct
    85321 ttttttacga aattttttag aggtgatgta aatgacaaaa caaaaacagc tgcttttagt
    85381 acctgcagta attgcaacag ggatgatgtc ttttgcgggc gtattgatcg agacggccat
    85441 gaatgtaact ttcccaactc ttatcagaca gtttgattta acgactgcac aagtccaatg
    85501 ggtaacaacg atttatcttt tgatgatttc gatcattgtt ccgctgtcta cttatttgaa
    85561 tcgcaatttt agtctcaaaa aactcttttt agcttcaaat ctgcttttct tggcaggtat
    85621 aatgatcgat ttcttctctc ctaccttcat ggtcctattg tttggtcgat tgctccaagg
    85681 tgcagcgaca ggtatcgctc ttccgttgat gttccatatt atcttgacat ttgcccccct
    85741 caatcgacga ggcgcgatga tgggtgtcgg tactttgaca acggccattg ctccagcaat
    85801 tggccccact tatggaggca ttatgacttc acattttaca tggaatcata tcttcctgtt
    85861 tcttgtgccc gttttgattc tttctttgat tatcggctgg tttgctattc ccgagatggc
    85921 agtacaaaaa agtggttatt tggattggat aagcgtttta ggaatttgtc ttttgtttag
    85981 tggaagtcta acatttttga gtacgttggg aacagtttcc agctggattg ctttaatcat
    86041 cggcggtatt ggctggttcc ttttttacta tcgaagtaaa aaagtggagc atccactgat
    86101 ccgactgtct attctttcaa ataaaacatt ccgcttgttt ttgattggct tcttagttta
    86161 tcagttttta ttacttggtg tatcttttgt cttgccgaat ttccttcaga tcgttcaagg
    86221 aagtagtcct tttgtcgctg gattagcgat gcttcccggc gcagcggttg gtgctttgct
    86281 ttctcctttt tccgggaaaa tgctggatca atatggtccg aagaagccaa tttttgctgg
    86341 gctgattctt tctttgattg gttggctagc attattccta ctcataggac acgcttcagt
    86401 gggtgtattg attgcttgtc atgtgtttta tatgatcggt atcggattat cttacagcaa
    86461 tatgatgacc accggaatga atgcactgaa tgaagaacta caaggagacg ggaacgcaat
    86521 gttcaatacc ttgcagcagt tttctggcgc tgtggctact tcattagtag cggtcattat
    86581 caattacgtc cagcatcata cttcccataa ctatgaagtg tctactacat taggatcaaa
    86641 agcagcatta ggcgtcttgt tgctgttgct tctcgtaagc tttgctcgat tcgcctatta
    86701 tctgttcttt gctaaaaaag cgtagattcc atatacggca ggtgttgcat ctgccgtttt
    86761 tttgtgtgaa aatggttgtt tgtaaaagga ggctttttta tggaaaaaat tgccattatc
    86821 ggtggcggga tcattggtat gaccctagcc agttacttag atacatcaaa attcaatgtt
    86881 gctttatttg atgaagggac aggacaggca actaaagcta gcgctgggat tatctcccct
    86941 tggttgtcga aacgcagaaa caaacaatgg tatcgtctgg ctaaagacgg cgctgctttt
    87001 ttccctaaac ttataaaaga tttccaactt gatcaaacga tttacgcaca atcagggaca
    87061 cttttgcttc gacctgaaaa agatttagct gaattggctg ttcttgccga gaaacgaaaa
    87121 gaagaagcgc cagaaattgg aaacatcgaa tggctttcac ctgaacagac atctcaagca
    87181 cttccgttat tgaaaccagc agtttcactg cgtatcagtg gtggtggtcg tctggatgga
    87241 aaagcatatt tagaacatct tggtcagcgt ttagcacaaa aacaaatgga gcagatccag
    87301 gcaaaagtca ctttgcataa gaagagcgat tcttggctca tcaagggacc gtttggagaa
    87361 tacacagctg atcgtgtaat tttgacacct ggcccggcac ttaagccttt attacaagaa
    87421 ttaggctatg ctgcagatat acgtccgcaa aaagggcagc tcttagcatt tcagacatct
    87481 tataagatga gtcaagactg gcctgttgct atgcttgacg gagaagctga tttcattcct
    87541 ttcatggatg gaaagatcct tttaggtgct acccatgaaa acgatcaagg ctgggatttg
    87601 gctcctacta gcgaagctta taagggattg actaagagta cagaacagtt cttgactgat
    87661 ccagatcaga taaaaaactg gccatacgag ttccgtgtag gtacccgtgc ttatacgtca
    87721 gatttttccc catttttcgg cgtactgcca gatgatccaa gcttactggc tgctagcggt
    87781 ctaggctctt ctggcttgac cacaggtcct tatatcggct atctattagc caacttctta
    87841 aatactggtc attggcctac ggaagattat caaaaggaca tctccaccta tattacgaaa
    87901 aatccatcat agaaaaacag ctttttcaag taaggatccc gagcgatatt gcgcatggat
    87961 tacttcttga aaaagctgtt attttagttc aatttctgaa tcaaattctc caaactttct
    88021 tttgcttcat ctggcaagag atcttttcct atctgagctt caatgaatcg taaacgaata
    88081 tcaagtcgtt gtttcaccag atttttatag gacgtatcct caaaagaaac aggaaaatct
    88141 ggtataggta aatagtggat gtcttcaaat ggaccaaacg acttgaattc tgccgtttgt
    88201 tgcacgattc tttcaacgat tgacaatgtc gtttcaggtt tgattttttt atcatcgaaa
    88261 tatccagtat tcaggacata gcaggctgtt tgctgtttca aaaacaactc tcgaaaagct
    88321 tgatagtctt ccctaagagg atagacacgg aaaggattag caaatggttc aatgactagc
    88381 tcatctagct gtctttttgt agtgatattt tccgcgtctg atcgttttgt tgctaatgtt
    88441 gcaccaaaag acgctgctaa aactgggtca ttgatcttga taattggcgg aagcgaatca
    88501 tctttcatga tccaaaaaac agcatcgatc ttttcgctaa gatgatcgac tcggtcgggt
    88561 gtcgcataac gtgatttgac tgtccgccca tttccgtttc gtatatctcc tgttactagg
    88621 actttttctc ctttacttgt acatgtcacg cccacattct gacaagtaag gaaagaagaa
    88681 atggccggat catcagacgg atagtcttgt gttttatcaa agtaagaagg ttccaaggca
    88741 gtagcaaaac cattttttcg agaaataacg aaagcatcgt catgcaagat cgaaacagag
    88801 tgaccttccg tatgttttgc taaggtaatc gttgattttc cagaaccgga caacccaaat
    88861 acagccatcg tataggtctg gtcattacta gcatattgtt tcatcccacc gtggcaggca
    88921 ataaagccat tgcgatttcc caatgcccaa gcaagcgtca aagtcgcttt ttttaattct
    88981 ccaaagtaac gtaatcctag cacaaccgct gtattatgga gagcatcaaa caaaatgagt
    89041 ccatttggaa atgtttcatg tgtccattcg ggatcacaaa agatataaag atctccctca
    89101 tcaaaggaaa cagacttttg ataagtctct aagatcttcg aattcgctgg ctgaaaattc
    89161 agcaaataag aatacaaatt gttctcaaat ccttctggaa tcagcaaatg actttgcaca
    89221 gaaaattctt cagataggcc aacgattact tttgtatggt aaaactggcg cttgcgactt
    89281 tgatacacag cttctcttaa aattttctcg tatttgcttt gttccttgtc taagtcctca
    89341 aagatccgcc gagcacttgc tgttcttccc acaatgcttc catcattgaa tactagtgtc
    89401 ctaacatcag ctggtaaatc tagttcttca gcatgtgaga ttgttaaatc tgtgatgatc
    89461 gttcctggac tcccttttgc tagttgataa gctgtcttcc tatcaaaaac ttcatgaaca
    89521 ttattaccgt aaaatgtcgt ttctacaatc gatcgaatac tggataacag tggatttcca
    89581 cttgtgattt cgtttaattc gagactctct tttgtactca tggctcctcc tcattcccta
    89641 aacaaaaaaa cgttttcttt attatacatt attcgagttt ttatttgtac tgctgcgctg
    89701 tgggaagcaa acgagttatt tttcacacaa aaaaaccgag aacttgaata aacaagtttc
    89761 tcggtttcat cattttcctt ttatcggctt agtaccagcc gtttgctaac cagaatgttt
    89821 tagcagcatc ccatgaacca taacgagatg ttacatattg ttctgctaca cgttcttgat
    89881 tggcagctga atagtcgccg tttaagtatg aagcatctaa ttgataacgg ccgatgtaac
    89941 gtccgttagt agctgtgtat gaaccgcctg attctttttg tgcgatccat tcttttgcag
    90001 agcttgaagt tggcgctgtt gcagcagctg gggcagcagg agctacttca actgtttcaa
    90061 caggtgcaac gtatgtatgt tcttgcgttg ctgtttcagt tgtagatgct gtattttctg
    90121 ttgttttgtt ttctgttgtt gctgaagaat catttgaagt tgggattgtt aattgttcac
    90181 caacataaat gcggttgatg tttgcgatcg aatttttttc agcaattgca tcgatcattg
    90241 agttgtctcc tgcaaatttt tgtgagatct tagataatga atcacctgat tttactgtat
    90301 aaacttcatc agcgtgagca tttgtagttc ctacaaacat tgcagtagca ccagcagcaa
    90361 aagttgtacc taaaacaatt ttcttaaatg aattcatatt aaactccttt ttttctccgt
    90421 tttttattct ttcgacgcta ttaactttat catttagaaa tatttcatag gtaaaagaaa
    90481 catgacattt aatgacaaaa taacgaatta tttaatattt gtaacattta aacaaatatt
    90541 tttttgatac aaaaccataa aagccttgtt gtataagcaa agtaatcgtt tttctatgtt
    90601 ttttttattt ttgaatgaaa aacgcagatt ctgtaacatt cactgcaata atccataaaa
    90661 aaaagcaaaa aaatttttga tttttatcaa attctcttaa aaaaatgtaa aaaatacaaa
    90721 aaaaccagta attgttacaa caattactgg acaaaaactt tgaataatgt taactatttt
    90781 tttattttaa ctttctccgc aataatttct gggcatgttc caattcgttt ataacgactt
    90841 cttctgtttc tttagctaat atttcatcta atacatcaag ccatttttcc ggttcttttg
    90901 ttcctagacg tccaatagcc caagctgctg ttcctctgat gacagggcgg acatctgtta
    90961 aacattctga aatctcaggc aatgccgttc gatcacctag attagctaaa gcaatcaatg
    91021 cgtttctctg caaaggtttc ttcccacgcc atgaaccagc taaatgccca aattgctgtt
    91081 tgaagtcttt attagacatc gaaagcattg gctttaattt tggatatatt tcgtctactt
    91141 ttggttccat ctcttcatga aaatgaaaat cttttccttg attgtaaggg cagactaact
    91201 ggcagatatc acatccataa atgacatttc gcattttttt acgatattct tccggcatca
    91261 tcccttttgt ctgagtttga taagacaaac atcgctgggc attcattctt ccgtcaccaa
    91321 gcaatgcttt tgtcggacaa gcagtcacgc agcgcataca gtcaccgcaa ccaaattctc
    91381 ctggtttatc aggctcaaat acaatattag taacgatctc accaagatag acaaatgaac
    91441 cgaactcttc agtgatcaac aatccgtttc gtccaataaa tcctaaacca gctcgctgtg
    91501 ctacagcgac atcgatcagt tctccagtat ctacttgcgg agctagacgc cattcctctt
    91561 ctttttgcca tttttctgct cttgtttgga tgaattcgat caatcggttc aaacggtctc
    91621 tgagtatatc atggtaatcg atcccccaag aagcacgagc aaactgcccg cgtttttcat
    91681 ccctaggcac ttcttcatgg atcctagtag gatacgcaag tgcaatggaa atgatcgatt
    91741 tcggctgatc aaatgtcatt tctggataaa gacgctcatc gatatttgga tgttcaaagc
    91801 cagaagtatg gccagctgct ttttgttctt ccaacgattc ttttaatgaa tcaaaaggtt
    91861 ccgccgtggt gaacccgatt ttgtcaattc ctaatcgttt gctttcttgt atgatttctt
    91921 cttttaatgt catggtcttc ctcgcttgct gttaacggct gtataaccca taatatagtt
    91981 tttctttttt cagctggaca aactggatct gctgatcggc attcttcttt tcttccatcc
    92041 atttttttct tgcagcaaat acttcccaat aatttgttga aattaatttt cttttgttat
    92101 ctaatgcatt aaaaaaattc aatgaaactg gttttgtact taacagttca tggagcctta
    92161 cctcttccca tggcgaaaac tcagacagat cgcgggaata caatacttct tcatagagat
    92221 ttttttgctg tgtgtacgtg aatgtttgcg ggattttccc aggcctagca atttctacta
    92281 gacgattata aaacatattc attaatttgc tgttggcaat aaattgactt ttataatagg
    92341 ccgactggat ctttttgatt actccttctg ctttgatgac tgaaaataat gcaggccatg
    92401 ctttgacggt tatttcgtcg ttttgtttaa ctaatacgcc aggtgtgaag ccgactggag
    92461 aaaggaacac aaaataaccg ataccggtat tttcatctaa aggctgaaat tcatcaaaca
    92521 accatttgcc tatgtacagc tcttcatctg gttctgttgt ctcattttga tttgctatga
    92581 ataatttagc taattctgct tcaagaaatt gaaggtcttg atccttgtcg gtattttcct
    92641 gctggctgat caatcgaaag acttcttctt taatcgtata tttatcttta cgtgtaaaat
    92701 tcatagccac accttccttc cttactctaa ctataacgga atttcttcaa aaaaggtatc
    92761 tgtacgacga aaaacagcat aatttttttt catatctctt ataaaaaatg caaggtctgc
    92821 tcctcaagct agaccttgca cttttcagct ttcttttgtt tgtgacaaac cttcatggat
    92881 cgtttcaata ttccatttca tcatctgata gtaagaatct ccttgttctc cttcttttgc
    92941 tatggaatca gtgaacagtt tatcatagat tttcaaaccc gtttcttttg ctacccgttc
    93001 catgcttctt gagtctacac tggtttccac gaataaaacc ggtacttctt ttgctcttat
    93061 ctgatcaatg atcgctttca tttgatcagg cgtaccttga ctttctgtat tgatctccca
    93121 tatataagct gctggcaaat catatgctcg tgaaaaatac ttgaatgccc cttcacttgt
    93181 tactaataat tttttgttct cttcgataga agcaaaactt tccttcgctt gtgtatctaa
    93241 ttcttttagt ttttccacat atgcttctgc atttttttat agagtgtcgc attttctgca
    93301 tctttttcag agaatatacg tgcgatttcc tccacatatt ttattccgtt agataggtct
    93361 agccaagcat ggggatctgc ttttgtatgt tcttcaccgc tagttaaata aagaggttct
    93421 acatttttgc taactgcaaa ataatctttt ccttcttctt ttttagccgt ttccatcaag
    93481 ttatcgaacc agctgttacc tgtttcaaga ttcaaaccgt tgtataaaat aacatctgca
    93541 tcgcttgcct ttttgatgtc ttctggtagt acttcatatt catgcggatc tgttccgact
    93601 ggtacgatac tgtggatatc tatttgatct gttccgacct cttttgccat gtccgccaag
    93661 atcgaattgg tagccacgac tgacaacttt tctttacttc cttcatccgc ttggtcagaa
    93721 gcctgctttc cgcaaccggc taataccaag aaactaactg ccaagattaa aaagagtgat
    93781 ttttttgttt tcatctatct gcttcctttc tgaaataaaa ttccttttgt tggagaaaat
    93841 aaaaaagcaa ggataaaaaa tgcggtacat gctaacacga tcgtagctcc tgatggccaa
    93901 ttgtaactat aactgaaaaa cacaccgaca actgcactta gcataccgat tcctgcagct
    93961 gtaatgatca ttttcagtaa atggttcgtt agcaagtaag ccgtggcggc tggtgtgatc
    94021 aacatggcaa tcaccaagat tgttcctact gtctgtaaac tgactacagc cactaatgtc
    94081 aaaaagaaca tcaaaagata atggatcagc gatgtgttca gcccataagc ttttgccatt
    94141 gtcggatcga atgatgtgat cttcaattct ttataaaaga aaaagacaaa tatcaagacg
    94201 attccactaa cgagtgctgt cagcaacaaa tcgctttccc taacagctaa gacattccca
    94261 aataaaatat gatacaaatc tgtcgcactc tgggcatatg aaatcaagat aatccctaat
    94321 gcaaaaaagg agctaaagac aattccaatc gctgtatcat ttttcaatcg gctccgctga
    94381 gtcacgaaac caatcactgc tgctgttagc atcccaaaag cagtggctcc aaagatgtaa
    94441 ctaaaaccaa acatataaga aatggctaca cctggaagaa ctgcgtgaga gatagcgtct
    94501 cccatcaaag acatccctcg taaaataata aaagaaccga tgactccaga agcaagtcct
    94561 acaagcatgg aagtgaccaa agcgtattgc aggaattgat aattcattaa tccatcaata
    94621 aaggattgga tcattttttc tctcctcctt ttactaaatg tctgatgatc tcaccatagg
    94681 ccaattgaag gttcttcgat gtaaagactt cttgtactgg accggaagcg atcagctgtt
    94741 tatttaaaag aataacctca tcgaaatatt cttctacttt atgaagatca tgatggacga
    94801 tcaaaatcgt ttttcctgaa ttcttcaatt cctgcaagat gtcaaagatc tttcgttcac
    94861 ttaacgcatc aatccctacg aatggttcat ctaaaaagat ccattctgct ccttgggcta
    94921 gagctcttgc aataaaaact ctctgaagct gtccacccga tagttcgctg atctgtcttt
    94981 tggcatattc ttccatccct acttttttca aagcttgtct tgcacgttct ttttcttttt
    95041 tcccaggtct ttgtccaatt cgtaaagatg gatatgttcc taaaagtaca acgcctaata
    95101 catcaattgg aaaggaaaga tccaattcac ttcgctgttc cacgtaggct atttttttac
    95161 ggactgagtt taccgactgt ccagaaaagg tgactttacc agtagtagct ggtatcaact
    95221 ctagcaaaga tttcataaat gttgattttc ctgcaccgtt tggtccgata ataccggtaa
    95281 ttttttgtgg atttatcgtc aagttgatag ttttcaaaac agttttccct tgataagcgg
    95341 ctgaaaggtc ttgaattaca atggccgtac gttccaaatc ttacactcct ttttaggttt
    95401 acctaacttt ttatttaaat atagtttaac taaaatggaa agcattttca agtagaatga
    95461 tgaaaaagtt tttttcgaat tttcctcgca ttttatgaaa attttctgta gaatcacatc
    95521 aagagttcaa taaggctaac ctaataatga aaaacatgtg ttgaaacgtt tgattatttt
    95581 ttcttgttga ctcaacaacg aaaggagttt ttgtatggaa gaagaaaagt taactcgaag
    95641 tcttagtgcc cgtcatatcc aaatgatcgc actaggtgga acgatcggtg tcggtctgtt
    95701 tatgggtgcc tcctcaacca tacgttggac agggccctca gtgatgggag cctatgcgat
    95761 tgcaggattc tttttgtatt tgattatgcg tgctttaggc gaaatgcttt acgttgatcc
    95821 ttcgactggt tcttttgcaa attacgcgag cgagtacatc catcctgtgg ctggctactt
    95881 gaccgcttgg agtaatattt ttcaatatat tgtcgtagga ataagtgaag tgattgctgt
    95941 aggatcttat atgaattatt ggtggcctga tttgccggca attattcccg gaatcattgt
    96001 cgtcttgttt cttatgctgg caaatcttat ttctgtcaag gcgtttggcg aattagaatt
    96061 ttggttttcg atcatcaaag tcataacgat cattttgatg atcattgcag gtcttggggt
    96121 aatcttattt ggatttggta atcatggtca ggcagtaggg atttcaaatc tttggaaaaa
    96181 tggtggattc ttcactggag gcgtcaaagg atttttcttt gcattatcga tcgttgttgc
    96241 ttcctatcaa ggaatcgaac tgatcggaat gactgctggt gaagcagaga atcctaaaaa
    96301 gacgatcatt gaagctgtcc agtccactat cggtcgaatc ttgatttttt atattggtgc
    96361 tatttttatc attgtgagta tctatccgtg gaatcaattg agtgagattg gttcaccttt
    96421 tgtacaaact ttttctaaag tcggcattac atttgctgca ggactgatta attttgtcgt
    96481 gattacagcg gcattatcag gttgcaattc agggattttc agcgcaagtc gtatggtcta
    96541 tacacttgcc ataaatggaa agatgtctaa aaaatttctg aaactatctc gtcacggtgc
    96601 gcctttttat cctgtcgtag caatctcagg tggaatctta attggtctga tcttaaatta
    96661 tcttctacca atgttcatca accagtcaga aaatattttc gttttcgtat acagctcaag
    96721 tattttgcct ggtatggttc cttgggtagt gattttgatc agcgagattc gcttcaaaaa
    96781 gaagcacgca gataaaatgc atgatcatcc ttttaaaatg ccactatctc cttatacgaa
    96841 ttatgtgaca cttgcttttt tagctatcgt attgattttc atgtttatca atcctgaaac
    96901 gagaatctca ttgattattg gactcgtttt cttgctttac atgacgatcc attactttgt
    96961 acgcgaaaaa agaaccggaa aataaaaaaa gaacgaagct tcaccttagt ggaagcttcg
    97021 ttctttttta ttgcttttat caattcaatt ttagcgtctc accgggagtc aggaaataat
    97081 tctccatgct catcccattc agcgacaaga tcgtttctac tggtacgcca gttcgttcgg
    97141 ctatttgatt tggaccttct ccttccaaaa ctacggttgt cgcagcctgt gaagtcgcgc
    97201 tgttggtatt agtttcagag gaatctgttg tgtcttgtgt tgttcgagct tgcatttcag
    97261 aagcttctac cgactctgct gtctcagaat cagaagatgt tgtgtcttgt gtgcttgttg
    97321 actctgcttg aagagaggcg ctagtctgca aataaatatc ggaaatctta gcgacatgat
    97381 tcgtataatt agccgataat tgattgatca aagtatctaa gtctacaccg tctttatttt
    97441 ctgctgcctg atacgctgca cgtaattttc tgatcccttc gtcggagatt gcttgaagct
    97501 cacgtgcttt ttggttagca actgctgata aaccagctat tccctcttga tttccctgaa
    97561 tttctgtctg gtattcttca atcaatgcag gcgtcttttc ttcgatcttt ttcgaataat
    97621 catttacgat tgcttgaagt tgctctggca aaccatttgc tgttttttct tcagaagttt
    97681 gtgtctcttt tgttttagtt gatgactcac ttgtttgttt cgtctctgtt ttctttgtcg
    97741 ttgtttccgt tatggtcgta cttttcgctt ctgacgaatt ttttccatga aaatatagac
    97801 ccgcaactcc tcctgctatg atcaaaaaca cggcaactgc tgccccaatc atgatcatcc
    97861 gcttacgagc tgcctgtttt tgctgtcttc ttcgggtcat ccgaacattt tctccccact
    97921 cattttcatc atacattttt ttcaccacca atttttatgt ataatagcgt tatcaaacgc
    97981 ttcatattct tattgtagca aataattgtc gctgtgcaca tttttatctt tgttatttat
    98041 aagaaaattt caccagttga gatgattcca agattgtccg tcgatttctc cttgcagctg
    98101 cattgttcgt tcgtctatct cagccatcag tttctttatt tcatataaga gcgcacggtc
    98161 ttgatattct gatttttcgc ttaattcatc taattgttgg atcagccaat catttgtcat
    98221 aatgaagttc ctttcatttc ttgcagtgta aaggtcaagt cttcgatctg ctcttttgcc
    98281 tcagtcagtg cttctacgat atatgcttgt ttttcagatt cttcttcctg cattttctga
    98341 ttttcctgta ctctttgaat aaaccagtca atccgctgag tcagcgatgg tttgccttcc
    98401 aatgagagat actgctgata agcaattagc ttctcccaac gtttttcctg ggataaatac
    98461 ataaattgtg ctaaaacgaa tggcggaaga taggtcatat ggaatttatt tgcgattcgc
    98521 tgatacggcc tcaaaaattc ggaaatcgta tattcttctt ttcctccagc ttggtattct
    98581 ttttccgcca cacctgttgt caatacgatt cctagttctt tcccttttaa tacatgtgct
    98641 gctcgttcca agacattatc ttgccaaatt tttaaatgag caggagaact ataccagtaa
    98701 aacggaaact ggaaaatgat ccgatcatgc tgggccaaga gctgtagttc agtctctata
    98761 tctatttttc cgtctggata acttgattcc aaatgatgcc aagtagctgg taaaccagca
    98821 gaagcttctt tgaaaaattg ctgatttaaa gattcttcga tcgttggatg gctaatgatg
    98881 ataagtgtac gcatcccttt tcctcctttt tagtcttcgc tttacagtgt agcataaccg
    98941 ccacaagttt cttttgccga tgcttgtcat tttaaccaga ctaatcaggt tgtccaagaa
    99001 actgtggttt gtttttccaa ctgttttttc aaggtatcca aagcaatatt cttaaaattt
    99061 ttgtttttca tacgtttacg atagttcgta gccgtttctc cggtactctt tttgaacatt
    99121 cggctaaata cgactagact attgaaccct acttgatagg caatactttc cacggattca
    99181 tccgtcagag aaagaagaaa cgcccctcga ttgatccgta ccccgatcaa atattccttg
    99241 atactggtac ccatatgatt tttgaatact cgcgacaaat ggctccgatt gaccgctaaa
    99301 tgctgggcga tttcctcaac agacaatttt tcagcataat gtgcctcgat gtatttgact
    99361 gtttcaacag ctaaagagga atgaaccttt tgtacaccac cgctgacctt tccgccatct
    99421 tttaaaagga ctgataaaaa acggtaggtt aatgctgtta actgtaattc attttccaag
    99481 gtttcttccg tatctttcat gcattctaaa ataatgtcga tatatttttg tatgtcagaa
    99541 gagaccatcg tgtattggtc ttctctgaaa agcgactgcc gaatgatttc ttctgcagca
    99601 ctcccaccaa atgaaagcca gcaatacatc cacggatctt ctccatctga taagtaaaac
    99661 gtcgagtctc ctggacgaat caagaacaga tcaccttttt tcaattggaa ttgttgattt
    99721 ttcacatgat aagatccttt gccttccatc acgacatgca ggatgtaatc attgcgaata
    99781 gcaggaccaa aagaatgaaa cggcatcgtt ttagagaaac cacaaaaatc aaaatacaat
    99841 tctttttcta cttgttgatg ttcctttttt aaaaaaatcg attgctccac gtctatccct
    99901 ccttactcct ttagtataat gcaacaaaaa gttaaataaa agtcacagaa atatattaaa
    99961 aaggaagcga tttcttgtta agtttaagtc attaaaagat ctttgttatt cgttgtaacc
   100021 ggtttactta gtattatata ttgaacagga gaggaataca gattatgaaa agcaaaatga
   100081 tccaacgtgt gtcctacgct ttaggcgctt ttggacacga cacattctat gttacattaa
   100141 gcacttattt tatggtattc gtgacaagcc agatgttcgc aggaacagat aaggcaacga
   100201 atgcaaaaat gattgctaca gttacaagct tagttgtagg tatccgctta gttgaaatta
   100261 tttttgatcc tttgattggt ggcatcatcg ataatactcg tacaaaatac ggtaaattca
   100321 aaccatggtt agttatcggc ggcgttgtta gttccgtact cttggtagca atctttacca
   100381 atttctttgg cttagctact cataatacga ctttatttat catattattt gcaatcgttt
   100441 tcatcttatt ggatagtttt tattcattta aggatatcgc tttttggtca atgattccag
   100501 ctttgagtac ggaaacaaag gaacgtgaaa aatttgctac gtttgctcgt ttcggctctt
   100561 ctctaggtgc aaatggtact actctagtcg ttgtccctat cgttactttc tttacctatc
   100621 ttgttactca taaacatatt gaaggcgctt caggctggtt ctggttcggt gtgattgctg
   100681 ctgttatttc aggcggtact gcgattatca ctgccttggg cacaaaagaa gtcgatactg
   100741 cgatccgtca gcaaaatgaa aaagctggga tcaaagatgt gttcaaagca gttgctcaaa
   100801 atgatcagtt gatgtggctt gcccttgctt atatcgctta tgcgattgcc aatgcagcaa
   100861 caactgccgt attattctac ttcttcaaat atgtacttgg ccaaccaact gaattttgga
   100921 tcgttggtct agttgctgcc ttacttggtt tagtagctgt tccactattc ccaatgctta
   100981 cacgcgtcat ctctcgtcgc tacgtttacc ttggagggat cgcaatgatg atttcttctt
   101041 actttttctt tacgatcgca ggttcaagtt tgccaatcgt tatcatcggg ctagtattgt
   101101 tctacttccc tcaacaattg attttcttat ccgctttgat gacgatcaca gactctgttg
   101161 aatatggtca atggaaaaat ggtatccgta acgaagctgt tactctatca attcgccctt
   101221 tactagataa aatcgctggt gctttgtcta acgggatcgt agggtttgtc gctatcgctt
   101281 ctgggatgac tggtaatgct actgctgctg atatcactgc tcatggcgta acgactttca
   101341 aagcttatgc attctatgct cctgctgctt tgatgatttt ctccgctatt atttttgctt
   101401 ggaagattac attgacagag aaaaaacatg cacaaatcgt tgagaaattg gaaaacaaat
   101461 tggctccagc tgatacaatg gaagatgaac ttcacgatgc agtagatcct tcccattaag
   101521 aaaggatctt gaaaatgaag attacagaaa aagattttgg ccaaggttat cacttgataa
   101581 ccttggagaa caaaaacaag ctagcacttt ctatctctga tttaggtgct agaatcgtca
   101641 gtttaaaatc aaatgatcga gaattagttt tgggatttga caccgctgaa gaatatatcg
   101701 aaaaagatcc gtatatcggt gcttctatcg gtcgcaccgc agggagaatc gaaaatggcc
   101761 acttttctct caatggaaaa acttaccaat tagccacaga tccaaaaact ggacataatc
   101821 tgcatggtgg tgctcctgga tttgaattaa aaaaatggtc ttatgtcatt ttgaatggcg
   101881 aaaatgaagc ttctgtcatt tttactacta caagtcccga cggagaacat ggttttccag
   101941 gtacaatgga tgtggaaatc cgctatactt tgacaaaaga taatatctgg cgagtgacct
   102001 ctcgcggcac cagtgaccaa gatactttat tcaatccgac aaatcatgtt tacttcaact
   102061 tgacgggaga tgcttctcag tcaatcgatc aacatgagct ttggctcaat agcgaagctt
   102121 atgctccttt gcgaacagat agtattccta taggggtaaa agaaaatgct gcaggaagtg
   102181 ctttcgattt tcaaatacct aaaaaattag cgtccgtttt tgctagtgat ttggatcaaa
   102241 aaaatcttgt tgacggaatc gatcatccat ttttcttaaa agaaaccggc ttgggtaaag
   102301 aagccgctcg cttgactagc cccgataaaa gaatccaagt agatattgct acagatgctt
   102361 ctagtgtggt tattttcact gcaaatttcg gcacagaaac accagaaatg cgcaaccgaa
   102421 aactggcaca tcacggtggc atcacatttg agactcaaac agctccaggt gcagagcgct
   102481 tctcagcatt tggttcgatt catttaaaag ccggatcagt atttgaaaca gtgacagaat
   102541 tcaaaatcaa aacaagaaag gaataactca tcatggaaat caaaagaagc ttaaacacaa
   102601 aatttgccga aacattcgga cctaaaaaaa ctacacaata cttctcacca ggacgcatca
   102661 atttgattgg tgaacacaca gattacaatg gaggccatgt cttccccgct tccatcactt
   102721 atggaacgca aggtgtagca gcacctcgag acgataataa aatattagtt tattccacaa
   102781 actttgacga tatcggtgtc attagtttta ctttagatga gctagaatat gataaaaaag
   102841 caaactgggc aaattacgta aaaggaatgg tccttaaatt aaaagaagct ggacactcaa
   102901 tcgatcatgg gtttgagtta ttagtggaag gaacaatccc taatggtgca ggactttcca
   102961 gtagcgcttc attagaatta ttagtaggtg ttgtattaga agatctgttt gatttaaaaa
   103021 cagatcgctt ggaactagtc caaacaggta aaaaagtaga aaatgaattc atcggtgtca
   103081 attcaggtat catggatcag tttgccatcg gcttcggtga gctagatcat gcaatcttat
   103141 tagatacaaa tacgctgaaa tacgaaatgg ttccagtgaa actagatggt tatgcaatcg
   103201 tcatcatgaa tacgaataag cggcgggaat tggcagattc aaaatacaat gaacgccgta
   103261 gcgaatgcga agaagccttg gcacgtttgc aaaaaacttt gcctatctct tctttaggag
   103321 acttagatga agaagaattt gaatcaacta ttgaccaaat cggcgatgat acattgatac
   103381 gcagagctcg ccatgccgtt tctgaaaatc agcggacttt gaaggcaaaa gctgaattag
   103441 aagctgggaa cttagaagca tttggtcaac tgttaaatga ttctcaccac tctcttcgct
   103501 atgattatga agtaactggg atcgaattag atacactagt agatgctgct caaaaacaag
   103561 aaggtgtctt aggtgcacga atgacaggag ctggatttgg tggctgtgcg attgctcttg
   103621 tcaaagaaga aaatatacct gccttcaaaa acaatgtcta tgatgaatac atgaaagttg
   103681 tcggctatgc tccggaattt tatgttgcac acattggaaa tgggacaaca aagatcgatc
   103741 cagaagctgt tcatgtttga taaaaaaatc aacgatctca gctaaaaaca aatagataaa
   103801 aataacctct cagcaatttc caaatgtgag ccttttgctc gtatttgaaa attgctgttt
   103861 tttattgaca cggaaagaga acgtgtgttc taattgtgtt gaagaggtga ttgttatgtg
   103921 ggcgaatcaa aatccggtat ttgtttatga aaaagaacct tcaagagata ttttatgtat
   103981 tgactgcaaa tctttttacg cctccgtaga gtgcgttgaa aaggatcttg atccccttac
   104041 aactaaatta gtagtcatgt cctatccgtc cgattcgaca gaaacacggg gtagcggatt
   104101 aatcttggct tccagtcctg cagcaaaaaa agcttacggc atcaccaata tcagccgtgc
   104161 cagagatctt cccttcccct atccaagtga tttatatatt gttgccccaa ggatggccta
   104221 ttatatggaa aagaacagag aaatcaattc tatctataaa aaatatgcag acgaagcgaa
   104281 ccatcatgtc tattccgtcg atgaaagctt ccttgatgta acaaatagca tggcactctt
   104341 tggtaaaaca aatgcgtacg acatggctaa actgatccat aaagatgtgt ttgagcagac
   104401 cggaatctac acgactatag gaattggcga taacccgcta cttgctaaac tagccttaga
   104461 caatggctca aaagacggaa agcaaatgtt tgctgaatgg cgttatgaag atgtaccaga
   104521 aaagttatgg aaaatctcag atatcactga cttttgggga atcggcaaac gaacagcaaa
   104581 acgtctgaaa caaatgggta tacattctgt ttatgattta gctcacgcgg attattatca
   104641 cttgaaaagc aagctagggg tcatcggtac tcagctttat gcccatgctt ggggcatcga
   104701 tcgaagtttt ttgggacaag aatatacacc aaaatcaaaa agtatcggaa atagtcaaat
   104761 cctagataga gattatacaa gacgagaaga aatcgagatc gttatcaaag aaatggccga
   104821 ccaagtcggc actcgcttga gacgatctgc agcaaaaaca caagtagtca gcttatgggt
   104881 aggatactct ttaggctatc ttgatccaaa tggcaagacc gggtttcacc agcaaatgaa
   104941 aatcgaagcg acaaatgcta gcagagatct agcagatgct ttattgacca ttttccacca
   105001 gcattaccac taccaggata ttcggcgtgt aggcgtgaac tgttccgacc tcgtatacgc
   105061 gacaggttta cagcttaacc tttttgaaga tcctgaaaag cagataaatg aagcgaaagt
   105121 tgattttgtt gtcgatacga ttagaaaaaa atacggcttt caatcaatca tccatgcgca
   105181 tagtctcttg caaggaggac gcgccatcgc acgtagttct ctcgttggcg ggcatgcagg
   105241 tggtatgagt ggattagaag gtggaaaaga tgagacggac agcaaaaaaa ttcattgact
   105301 ataacgagta tcgagatcgg ccatttggat taaaatgggg gactgctttt gcgatggaag
   105361 aactagtcaa cggtatcaaa aaaaatgaag aagaagcacg caaacagcct cttcctaaac
   105421 aacaaatgac attgcaagaa atcgatagta tactgacaga agccttttta tctcgtaaag
   105481 cagtaatcat tcagctcaat ttaaaagatg aatttggaag actcttggat gaggtcgaag
   105541 ggcacttcat tggtgaagcc tatgaagatt actttatgat tgaccatcag ccgatattgt
   105601 gggaagacgt acggtatatt gagttaaagg aaacaaaaaa atggtttgtg acatgagagg
   105661 ttgtgacaga agtgatcaac ttcaaaaaat aagaaaggat ttttcgaaaa ttgcttctta
   105721 aatttttgtg gaattttggc ttatttttcg aagaagcaac ttctggaaca acgtatatta
   105781 gatatcagag gttgtgaaaa agtcgcttag ttttgagtaa caagccaagg cgctgatttc
   105841 acaacctctg tctatctatc catctattcg gtaagattca tgcatgacgt cttctttatt
   105901 tagtatgtag agcccttttt cttctgacca ttcaacataa atcagctgtt ttacatctgc
   105961 atagccttct ttcttcaagt tctccataag ccatgcttca gtcaattgat tggactgaag
   106021 cactttatgc tgaatttgcc cttcatctac aagcaggatc gataaagctt tgtcttcatc
   106081 tgattttttc aatacactca tttgaccggc attctctagg ataacatgtt tggcattttc
   106141 aagaaaaaag cattcttgct gtcttaagat tgctcgcaac tgctccatct cgatatggtt
   106201 atttgtcaac tctgtcatgt tgatgacgcc gtctttgatt agaacagatg gctcgccttt
   106261 gacccaacga ttgacctttt catttttttg gacgatacgt tcgataccat aaatcattac
   106321 tgcccaaagc gcaatggcaa ataggacatg ccctacatgg acattgtcat cataggttga
   106381 ttcttctaag atcccaccta aaacaagcgt atagactaaa tcaaacggtg tgatttctga
   106441 catggatttc ttcccaagca aacgtaccac taataataaa ccgatcaacc cgaacaccag
   106501 tttcattgta attgaaaaaa tcattttttc tccccctaac tatctgttaa ttaaattata
   106561 tatgctttct cacgaacacg catggaatat acaaggaaga aatgtatcct tttactaaaa
   106621 aaaggactgt gacactgtag tgacccccaa aagttagact tttttggagt ggagaaatcc
   106681 actccttttt tttatgctct aaaatgatat ttttacacaa ccgttacggt tgttttacga
   106741 aattggacg
//
LOCUS       DARPZF010000004        99407 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.004, whole genome shotgun sequence.
ACCESSION   DARPZF010000004 DARPZF010000000
VERSION     DARPZF010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 99407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 99407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..99407
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.004"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            9..587
                     /locus_tag="SLE65_000405"
     CDS             9..587
                     /locus_tag="SLE65_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447729.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(827..910)
                     /locus_tag="SLE65_000406"
     tRNA            complement(827..910)
                     /locus_tag="SLE65_000406"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(874..876),aa:Leu,seq:gag)
     gene            965..1144
                     /locus_tag="SLE65_000407"
     CDS             965..1144
                     /locus_tag="SLE65_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447730.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            1293..2510
                     /locus_tag="SLE65_000408"
     CDS             1293..2510
                     /locus_tag="SLE65_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEI8447731.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            2694..3530
                     /locus_tag="SLE65_000409"
     CDS             2694..3530
                     /locus_tag="SLE65_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8447732.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            3606..4754
                     /gene="nagA"
                     /locus_tag="SLE65_000410"
     CDS             3606..4754
                     /gene="nagA"
                     /locus_tag="SLE65_000410"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEI8447733.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            4975..6033
                     /locus_tag="SLE65_000411"
     CDS             4975..6033
                     /locus_tag="SLE65_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HEI8447734.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            6037..7071
                     /locus_tag="SLE65_000412"
     CDS             6037..7071
                     /locus_tag="SLE65_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HEI8447735.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(7173..7889)
                     /locus_tag="SLE65_000413"
     CDS             complement(7173..7889)
                     /locus_tag="SLE65_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEI8447736.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(7858..8643)
                     /locus_tag="SLE65_000414"
     CDS             complement(7858..8643)
                     /locus_tag="SLE65_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HEI8447737.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(8634..9383)
                     /locus_tag="SLE65_000415"
     CDS             complement(8634..9383)
                     /locus_tag="SLE65_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEI8447738.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            9681..10205
                     /locus_tag="SLE65_000416"
     CDS             9681..10205
                     /locus_tag="SLE65_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HEI8447739.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            10221..11720
                     /locus_tag="SLE65_000417"
     CDS             10221..11720
                     /locus_tag="SLE65_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HEI8447740.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(11808..12410)
                     /locus_tag="SLE65_000418"
     CDS             complement(11808..12410)
                     /locus_tag="SLE65_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEI8447741.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            12514..13470
                     /locus_tag="SLE65_000419"
     CDS             12514..13470
                     /locus_tag="SLE65_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEI8447742.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(13775..14731)
                     /locus_tag="SLE65_000420"
     CDS             complement(13775..14731)
                     /locus_tag="SLE65_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEI8447743.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            14905..15465
                     /locus_tag="SLE65_000421"
     CDS             14905..15465
                     /locus_tag="SLE65_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447744.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            15458..16282
                     /locus_tag="SLE65_000422"
     CDS             15458..16282
                     /locus_tag="SLE65_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEI8447745.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            16292..16909
                     /locus_tag="SLE65_000423"
     CDS             16292..16909
                     /locus_tag="SLE65_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEI8447746.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            16927..17610
                     /locus_tag="SLE65_000424"
     CDS             16927..17610
                     /locus_tag="SLE65_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HEI8447747.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            18293..19576
                     /locus_tag="SLE65_000425"
     CDS             18293..19576
                     /locus_tag="SLE65_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEI8447748.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            19592..20479
                     /locus_tag="SLE65_000426"
     CDS             19592..20479
                     /locus_tag="SLE65_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8447749.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            20496..21332
                     /locus_tag="SLE65_000427"
     CDS             20496..21332
                     /locus_tag="SLE65_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEI8447750.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            21335..21958
                     /locus_tag="SLE65_000428"
     CDS             21335..21958
                     /locus_tag="SLE65_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447751.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            21955..23247
                     /locus_tag="SLE65_000429"
     CDS             21955..23247
                     /locus_tag="SLE65_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEI8447752.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      23606..23703
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            23819..24400
                     /locus_tag="SLE65_000430"
     CDS             23819..24400
                     /locus_tag="SLE65_000430"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEI8447753.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            24403..25710
                     /locus_tag="SLE65_000431"
     CDS             24403..25710
                     /locus_tag="SLE65_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEI8447754.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            26126..26614
                     /gene="purE"
                     /locus_tag="SLE65_000432"
     CDS             26126..26614
                     /gene="purE"
                     /locus_tag="SLE65_000432"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEI8447755.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            26607..27731
                     /gene="purK"
                     /locus_tag="SLE65_000433"
     CDS             26607..27731
                     /gene="purK"
                     /locus_tag="SLE65_000433"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEI8447756.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            27744..29039
                     /gene="purB"
                     /locus_tag="SLE65_000434"
     CDS             27744..29039
                     /gene="purB"
                     /locus_tag="SLE65_000434"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEI8447757.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(29219..29596)
                     /locus_tag="SLE65_000435"
     CDS             complement(29219..29596)
                     /locus_tag="SLE65_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447758.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            29852..30580
                     /locus_tag="SLE65_000436"
     CDS             29852..30580
                     /locus_tag="SLE65_000436"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEI8447759.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            30580..30834
                     /gene="purS"
                     /locus_tag="SLE65_000437"
     CDS             30580..30834
                     /gene="purS"
                     /locus_tag="SLE65_000437"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HEI8447760.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            30836..31507
                     /gene="purQ"
                     /locus_tag="SLE65_000438"
     CDS             30836..31507
                     /gene="purQ"
                     /locus_tag="SLE65_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HEI8447761.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            31508..33730
                     /gene="purL"
                     /locus_tag="SLE65_000439"
     CDS             31508..33730
                     /gene="purL"
                     /locus_tag="SLE65_000439"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HEI8447762.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            33715..35154
                     /locus_tag="SLE65_000440"
     CDS             33715..35154
                     /locus_tag="SLE65_000440"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEI8447763.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            35177..36229
                     /locus_tag="SLE65_000441"
     CDS             35177..36229
                     /locus_tag="SLE65_000441"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEI8447764.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            36226..36804
                     /gene="purN"
                     /locus_tag="SLE65_000442"
     CDS             36226..36804
                     /gene="purN"
                     /locus_tag="SLE65_000442"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEI8447765.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            36801..38336
                     /gene="purH"
                     /locus_tag="SLE65_000443"
     CDS             36801..38336
                     /gene="purH"
                     /locus_tag="SLE65_000443"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEI8447766.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            38352..39626
                     /gene="purD"
                     /locus_tag="SLE65_000444"
     CDS             38352..39626
                     /gene="purD"
                     /locus_tag="SLE65_000444"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEI8447767.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            39748..40662
                     /locus_tag="SLE65_000445"
     CDS             39748..40662
                     /locus_tag="SLE65_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEI8447768.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(40795..42360)
                     /locus_tag="SLE65_000446"
     CDS             complement(40795..42360)
                     /locus_tag="SLE65_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEI8447769.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(42353..43804)
                     /locus_tag="SLE65_000447"
     CDS             complement(42353..43804)
                     /locus_tag="SLE65_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEI8447770.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(43818..44834)
                     /locus_tag="SLE65_000448"
     CDS             complement(43818..44834)
                     /locus_tag="SLE65_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEI8447771.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            45054..46142
                     /locus_tag="SLE65_000449"
     CDS             45054..46142
                     /locus_tag="SLE65_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HEI8447772.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            46196..47722
                     /locus_tag="SLE65_000450"
     CDS             46196..47722
                     /locus_tag="SLE65_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HEI8447773.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            47724..48929
                     /locus_tag="SLE65_000451"
     CDS             47724..48929
                     /locus_tag="SLE65_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8447774.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            49186..50163
                     /gene="guaC"
                     /locus_tag="SLE65_000452"
     CDS             49186..50163
                     /gene="guaC"
                     /locus_tag="SLE65_000452"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEI8447775.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            50427..51851
                     /locus_tag="SLE65_000453"
     CDS             50427..51851
                     /locus_tag="SLE65_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEI8447776.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            52312..53421
                     /gene="pdhA"
                     /locus_tag="SLE65_000454"
     CDS             52312..53421
                     /gene="pdhA"
                     /locus_tag="SLE65_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HEI8447777.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            53424..54401
                     /locus_tag="SLE65_000455"
     CDS             53424..54401
                     /locus_tag="SLE65_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEI8447778.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            54426..56069
                     /locus_tag="SLE65_000456"
     CDS             54426..56069
                     /locus_tag="SLE65_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HEI8447779.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            56077..57483
                     /gene="lpdA"
                     /locus_tag="SLE65_000457"
     CDS             56077..57483
                     /gene="lpdA"
                     /locus_tag="SLE65_000457"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEI8447780.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            57645..57920
                     /locus_tag="SLE65_000458"
     CDS             57645..57920
                     /locus_tag="SLE65_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEI8447781.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            57926..58693
                     /locus_tag="SLE65_000459"
     CDS             57926..58693
                     /locus_tag="SLE65_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEI8447782.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            58861..60690
                     /gene="typA"
                     /locus_tag="SLE65_000460"
     CDS             58861..60690
                     /gene="typA"
                     /locus_tag="SLE65_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEI8447783.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            60951..62723
                     /gene="recQ"
                     /locus_tag="SLE65_000461"
     CDS             60951..62723
                     /gene="recQ"
                     /locus_tag="SLE65_000461"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HEI8447784.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGRNKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            62837..63139
                     /locus_tag="SLE65_000462"
     CDS             62837..63139
                     /locus_tag="SLE65_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HEI8447785.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            63142..64305
                     /locus_tag="SLE65_000463"
     CDS             63142..64305
                     /locus_tag="SLE65_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEI8447786.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            64331..67759
                     /locus_tag="SLE65_000464"
     CDS             64331..67759
                     /locus_tag="SLE65_000464"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HEI8447787.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            67780..68904
                     /locus_tag="SLE65_000465"
     CDS             67780..68904
                     /locus_tag="SLE65_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447788.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            68894..69331
                     /locus_tag="SLE65_000466"
     CDS             68894..69331
                     /locus_tag="SLE65_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEI8447789.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            69315..69653
                     /locus_tag="SLE65_000467"
     CDS             69315..69653
                     /locus_tag="SLE65_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEI8447790.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            69772..70332
                     /gene="rsmD"
                     /locus_tag="SLE65_000468"
     CDS             69772..70332
                     /gene="rsmD"
                     /locus_tag="SLE65_000468"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEI8447791.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            70329..70820
                     /gene="coaD"
                     /locus_tag="SLE65_000469"
     CDS             70329..70820
                     /gene="coaD"
                     /locus_tag="SLE65_000469"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEI8447792.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            70810..71853
                     /locus_tag="SLE65_000470"
     CDS             70810..71853
                     /locus_tag="SLE65_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEI8447793.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            72012..72740
                     /locus_tag="SLE65_000471"
     CDS             72012..72740
                     /locus_tag="SLE65_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEI8447794.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            72856..73101
                     /locus_tag="SLE65_000472"
     CDS             72856..73101
                     /locus_tag="SLE65_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEI8447795.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            73098..73316
                     /locus_tag="SLE65_000473"
     CDS             73098..73316
                     /locus_tag="SLE65_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HEI8447796.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            73452..73991
                     /locus_tag="SLE65_000474"
     CDS             73452..73991
                     /locus_tag="SLE65_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HEI8447797.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            73984..76257
                     /locus_tag="SLE65_000475"
     CDS             73984..76257
                     /locus_tag="SLE65_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEI8447798.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            76295..77341
                     /gene="holA"
                     /locus_tag="SLE65_000476"
     CDS             76295..77341
                     /gene="holA"
                     /locus_tag="SLE65_000476"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEI8447799.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(77430..77684)
                     /locus_tag="SLE65_000477"
     CDS             complement(77430..77684)
                     /locus_tag="SLE65_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEI8447800.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(78084..78353)
                     /locus_tag="SLE65_000478"
     CDS             complement(78084..78353)
                     /locus_tag="SLE65_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447801.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(78823..79278)
                     /locus_tag="SLE65_000479"
     CDS             complement(78823..79278)
                     /locus_tag="SLE65_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HEI8447802.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(79416..81344)
                     /locus_tag="SLE65_000480"
     CDS             complement(79416..81344)
                     /locus_tag="SLE65_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEI8447803.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(81541..82374)
                     /locus_tag="SLE65_000481"
     CDS             complement(81541..82374)
                     /locus_tag="SLE65_000481"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEI8447804.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(82566..83270)
                     /locus_tag="SLE65_000482"
     CDS             complement(82566..83270)
                     /locus_tag="SLE65_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEI8447805.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(83293..83919)
                     /locus_tag="SLE65_000483"
     CDS             complement(83293..83919)
                     /locus_tag="SLE65_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEI8447806.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            84245..86620
                     /locus_tag="SLE65_000484"
     CDS             84245..86620
                     /locus_tag="SLE65_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HEI8447807.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(86644..87135)
                     /locus_tag="SLE65_000485"
     CDS             complement(86644..87135)
                     /locus_tag="SLE65_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HEI8447808.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            87322..88242
                     /locus_tag="SLE65_000486"
     CDS             87322..88242
                     /locus_tag="SLE65_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEI8447809.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            88396..88740
                     /locus_tag="SLE65_000487"
     CDS             88396..88740
                     /locus_tag="SLE65_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEI8447810.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(88930..89430)
                     /locus_tag="SLE65_000488"
     CDS             complement(88930..89430)
                     /locus_tag="SLE65_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8447811.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            89958..90041
                     /locus_tag="SLE65_000489"
     tRNA            89958..90041
                     /locus_tag="SLE65_000489"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:89992..89994,aa:Leu,seq:cag)
     gene            complement(90365..91003)
                     /locus_tag="SLE65_000490"
     CDS             complement(90365..91003)
                     /locus_tag="SLE65_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEI8447812.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            91338..91772
                     /locus_tag="SLE65_000491"
     CDS             91338..91772
                     /locus_tag="SLE65_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEI8447813.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            91795..92115
                     /locus_tag="SLE65_000492"
     CDS             91795..92115
                     /locus_tag="SLE65_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447814.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            92256..92447
                     /locus_tag="SLE65_000493"
     CDS             92256..92447
                     /locus_tag="SLE65_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447815.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(92518..92775)
                     /locus_tag="SLE65_000494"
     CDS             complement(92518..92775)
                     /locus_tag="SLE65_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HEI8447816.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            92933..93196
                     /locus_tag="SLE65_000495"
     CDS             92933..93196
                     /locus_tag="SLE65_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447817.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            93220..93408
                     /locus_tag="SLE65_000496"
     CDS             93220..93408
                     /locus_tag="SLE65_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447818.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(93491..93676)
                     /locus_tag="SLE65_000497"
     CDS             complement(93491..93676)
                     /locus_tag="SLE65_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447819.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            93891..94262
                     /locus_tag="SLE65_000498"
     CDS             93891..94262
                     /locus_tag="SLE65_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEI8447820.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(94412..94484)
                     /locus_tag="SLE65_000499"
     tRNA            complement(94412..94484)
                     /locus_tag="SLE65_000499"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(94449..94451),aa:Gln,seq:ctg)
     gene            complement(94530..94958)
                     /locus_tag="SLE65_000500"
     CDS             complement(94530..94958)
                     /locus_tag="SLE65_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447821.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(95018..95776)
                     /locus_tag="SLE65_000501"
     CDS             complement(95018..95776)
                     /locus_tag="SLE65_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HEI8447822.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            96071..96268
                     /locus_tag="SLE65_000502"
     CDS             96071..96268
                     /locus_tag="SLE65_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447823.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            96374..96856
                     /locus_tag="SLE65_000503"
     CDS             96374..96856
                     /locus_tag="SLE65_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447824.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(96914..97510)
                     /locus_tag="SLE65_000504"
     CDS             complement(96914..97510)
                     /locus_tag="SLE65_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEI8447825.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            97897..99363
                     /locus_tag="SLE65_000505"
     CDS             97897..99363
                     /locus_tag="SLE65_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HEI8447826.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT        32262 a        17026 c        21141 g        28978 t
ORIGIN      
        1 ttttagacat gaatatctta tttttattgc tatttttctt aattttcctt ctaacatata
       61 ggaaatgtca aaactattat gtgcgtatat tgactgcatt accgtttttc ttaaacctga
      121 ttatttattt tggtaataca atgggtcaaa gctttactta cgtcaatgga aataaaaggg
      181 caatgatttg gagtagtagt aacctgaata atctctttac agagttagga acgaaactgt
      241 cactttttta tccaggtact tggatagcta ctttagtagt cttggcatta ttactatgtt
      301 taattgttgg aatttattta agttttgaca ataagaaaac ttctattttt ttagttattt
      361 tgatgataat gggattttgt tcaaggttaa ttatgggatt ttctcccaca gtatgggctt
      421 ccggaatgcg gacgtactat atactttatg ttgttatcgc catcttagta ctaatggcag
      481 ttaaagagct aatgaaaagc atgagtgtac aaaaaaatga atttatgcaa tttggattaa
      541 ccgtgcttgg tatttgtacc tttataataa cggtgataaa cagataatat acaaaaaatc
      601 cctcgcttta gtattaggtg agggatttta ctcgtttttc gattaattgt tttaacactt
      661 gcaagtttct acgagtagct tgtttccgac cttcatatac tcacctcagg ctgtttacat
      721 gattgtacgt tctttttgta aaggatacag tgatatgtat ataatggcat aaagaaacgt
      781 tcaaacaaaa aaactcgtga agcaaaatta acttcacgag ttgtagtgca gatgatggga
      841 ctcgaaccca cacgagctaa cgctcacatg accctcaatc atgcttgtct gccaattcca
      901 acacatctgc gtaataataa cacactaatg atagcgaggt tttacatagt tgtcaagctc
      961 aaaaatggga ggacttatta agatggagaa atatgacgga gaattttcag gactgggaat
     1021 gatcttaggt gtattgattg gacttgcatt cggacgtttt ttgcttggtt ttatgctagg
     1081 aatcatttgt ggaatcgcaa tggattgggc agcgaatcta tggaatgact atcatgacaa
     1141 ttaagttctc aacgcttgtt tgtgtttttt taatacttac gtttttccta aataagtggc
     1201 aaaattttct aggatggagt atgatattga aatagtaaat aacaaaaaat ttggaaagtt
     1261 ctaacttttt gaaatgaggg attggctaag tgatgagaga atttgaaaaa tccaacaaat
     1321 tagaaggtgt cagttacgat gttcgcggtc ccgttctaga agaagcggag cggatgcaag
     1381 aagagggcat tagtatttta aaattgaaca cgggaaatcc cgcacctttt ggatttgaag
     1441 caccaaacga agtcattcgt gatttgatca tgaatgcccg tgactcagaa ggctactcag
     1501 attccaaggg gatcttttct gctagaaaag caattgagca atattgccaa ctgaaacatt
     1561 ttccgaatgt gacgatcaat gatatctaca ccggcaacgg agtgagcgaa ttgatcacga
     1621 tgtgtatgca ggggttgctg gacaatggag atgaagtact ggttccaatg ccggactatc
     1681 cgttgtggac ggcttctatt gcattagctg gaggcacacc tgttcattat atttgcgatg
     1741 aagaggcaga atggtatcct gatattgatg atatcaaatc aaaaataacg agtcggacaa
     1801 aagctattgt tatcattaat cctaataatc ctactggggc actttatcca aaagaattat
     1861 tagaagaaat cgttgaagta gctcgacaaa ataacctgat tatttattcc gacgaaatct
     1921 atgatcgctt agtgatggat ggtctagaac atattccgat tgctacatta gcgcctgatt
     1981 tgttcgttgt tacgctgaac ggtctatcca aatctcatcg tgtagcagga tttcgagtag
     2041 gctggatggt cctaagtgga gataagtcac acgtcaaagg ctatatagaa gggctgaata
     2101 tgttgtcctc catgcgtttg tgttccaatg tattgtctca gcaaattatc caaaccgcgc
     2161 taggcggtta tcaaagtgtc gatgagctgc tcctgccagg cggaaggatc tatgaacaaa
     2221 gagaatatat ctataatgca atcaatgata ttcctggtct ttcagccgta aaaccaaaag
     2281 ctgcttttta tatattccca aaaattgata caaagcgatt caatattttg gatgatgaaa
     2341 aattcgtttt ggacttttta catgaacatc atattctact tgtacatggt ggtggattta
     2401 attggaacca gccagatcat tttcgaatcg tttatcttcc taaaatggat gatttgaaac
     2461 aaacagctaa gaaaatgaga gaattcctag caacctatcg ccaaaaatga ttttaaaaac
     2521 caaatttttc agtaggaggg ccacagacaa acacactgag gctctctttc tagtggagtt
     2581 ttcttaaata actaaagtat attatttagt tgcaagtctt ttcttgaagt ttgcgacttc
     2641 ctaaagtaaa atacgaatag aatgcgaata cgcatatttt ggggaggata cttatggaaa
     2701 cgttaatcga gtcctttgga acgatcatta aagagattcg aaaagaacaa aaaatgacgc
     2761 aaaaaatgct ttcgcatgat atttgttcac aaagtgtatt aagtcggatc gaaaataatg
     2821 aggaactgcc gaatgtattg gtgatgatgc agatttgtca acggctaggg gtaacgattg
     2881 atcatgtgat gaatctctct cgaaaaacta ctcggacaaa cgataaatta tttgaactgt
     2941 tggatagttg tttccaaaaa cgtgattatc ggaagttaga acaagtacta aaatcttctg
     3001 atatttctga aaatctgtat caagcaactg actttcaacg ctattattat tatctcggtg
     3061 tttgcgaatt cacgttgcgt caaaatatct ctcagtccct ttattatttg aaagaagcat
     3121 taagctactc tagccaaaaa gaaagaatcc atgtttctga cacagaaata caactgatta
     3181 gttgtatcgg aaaaatatat ggtgtggcag gaaaaacggc tgaagcacgc tactatttga
     3241 gtcgaagcat ccaactgctg catcaatcag ctgatgaacg atcaaaaagt gaattttcgc
     3301 aaatttttta taattatgga aatttcttat tccatcaaaa tgaaatcgac gaagcgttag
     3361 aacaggtgaa tcaaggaatc tattgggctc aagagaagaa tagctactat tacctcaatg
     3421 atttatttgt gcttaaaagc ttaatataca agcgtaaaga agaaccagaa agagcagcat
     3481 tctatgaagg cttagcacaa gctgtgaaac aaatttcaaa aaatttgtaa atggtgtaga
     3541 ccattcttga cttcttctct aaataagagt actttagagg tagaaaaaca aagggagaga
     3601 atagaatgag aacttttatc tatgctgaca aattcttttt agcgtcaggt gtcaaacatg
     3661 caggctatct tgaaattacc gatggacttt ttggtgaata caccaaagaa ctacctgagg
     3721 gagaagtcaa catcattgac caaagcggca aatggattgc tcctggtttg gtagatacac
     3781 atattcacgg ctatatgaat catgatgtaa tggataatga tgcagaaggc atcaaagtga
     3841 tgtctgaagg tctgttatct tgtggagtga cttcattttt accaacaaca ttgacgtcaa
     3901 gcaaagaacg tttaaaagat gtagctgaga caatcggcaa aatgtatcag gaagcaccag
     3961 gagctaaaat caaaggaatc tattttgaag gtcctttctt cacagaagaa cacaaagggg
     4021 cacaaaaccc aagttatttc ggggatcctg atttggatac tttccatgaa tggcaagaag
     4081 cttcaggtgg tttaatcaaa aaaattgctt tagcaccgga acgtcaaggt gtagaagagt
     4141 ttgtcaaaca agtgactgaa gaaggagtag ttgtttctct aggacacagt aatgctacac
     4201 tagaagaagc gcaaaaagct gttgaagcag gcgcaagtgt atttgtccat gctttcaatg
     4261 gtatgcgtgg attgaatcat cgcgaaccag gtatggtggg tgcgttatta tctttagaac
     4321 atgtcttttc tgaattgatt tgtgatggcc atcatgtaca tccaaatgct gcgggaatcc
     4381 taatggaaaa agcaggacat gatcatgtcg cattaattac agactgtatg atggccggtg
     4441 ggatgcctga tggaaattac aatttaggcg aatttccagt agtagtaaaa gaaggaacag
     4501 cacgtctaga atctggcaac ttagctggaa gtatattgaa attgaaagaa gcaattaaaa
     4561 atgttgtaga ctggggatta gcaacaccag aacaagcagt catgatggct agtctgattc
     4621 cagcaatcag ctgtaaaatc gatgatacat gtggaaaaat cgctcaagga cgcgatgcag
     4681 actttatcgt attgaaccct gatatgacat tggaagcaac ttatctagat ggcgtggaac
     4741 gtttccacgc ataatataat ttaagttaac cttaaaacta aacttcttaa gtttggtttt
     4801 aaggtttttt ttgtgttcta gtaaaaatca ctttacataa gtttcaaaag tttctttaat
     4861 ttcctattgt tcaataagta acaatgtaaa gataaaatta aaaatgttaa tacgtattag
     4921 caaaataaaa gcttttttta ttgtgaataa atgaacataa ttaggaggag aaagatgaac
     4981 ttatttgaca tttttcgatc gactttgaca gatatgtcga ttgtcagtgc aatcacttca
     5041 acagttttta ttatattatt agggtttgtt tgtagaaaaa aggggatttt ttctgaatct
     5101 gttggaaaaa ttctatcgaa agtcgtctta acagtggctt tgccagcact ggcatttcga
     5161 gctttcatgc aagatatcaa tacagaatta ctgatgcaag gaatcaatgt cttgatttgg
     5221 ggattagtta tttatattat tcttattcta gtttcaaaac cttttttctt aagctataaa
     5281 ggggataagc aaacaacgtt gcgtgtcctg acgatctttg gttctacgac ctttttcgga
     5341 acgcctatcg tcagtgcgat ttatggtcct gtcggcgtga tgtattcctc aattttcaat
     5401 attggctacc gaatcttttt gtattcttat ggatacataa aaatgagtgg cttgaagatg
     5461 gaagctaaaa atatcaaagc gatgttcgtc aatccaatca ttatcgctac ttttgccggc
     5521 cttttcattt ggctgttcca agggtatctg ccacaagtgt cagttacagg tgcagaagga
     5581 gagataagcc aagtagcgtt tttgcgaatt gaccagactg caccgtggct atttcagccg
     5641 atggattatt tagctggttt aagttcacca ttggcgtggc tagcaatcgg cgcaacatta
     5701 ggtgaagtaa gcttcaaaaa agctgcatct gaaaaaactt catggtatta cagtctagtc
     5761 aaagtggtat ttgtacctgc attgaatatc gtgattctag cagttttgac ggcaacgaat
     5821 attctaccag tcaattttga agcactggca acaatcgtta tcatgatggc tacaccagct
     5881 gcaacagtgg cagcagccta tgctatcagt tttgataggg aggcactttt agcctccaat
     5941 gcatccttac tgtcaactat ttttgctgtg gtactgacac ctgtatggat cgttgtatta
     6001 caaatgattc atggcatagg tttattttca taagaaatgg aggaagaaag tatgagaatc
     6061 gcatgttacg gtgttcgtcc gaacgagata gatttttttg aaaaattgaa tatttaccat
     6121 tatgatctca gtctttatga agaactgttg acacatgaca atatcgtgtc agcaaaggac
     6181 catgatgctg tattgttgag gggaaattgt atagcagatg agaccaatct tgcaaaaatg
     6241 caggaatatg ggattcgtta tgtttttaca cggactgtgg gagtcaatca tatcgatcta
     6301 caagcggcag ctgattttgg tatgacagta gcccgtgtac catcgtattc gccaaatgcg
     6361 atagcagagt tatctttgac ttttgccatg atgcttttga gaaatactgc gtatacgacg
     6421 atccgaacat ctttcaaaga ttttcgagtg gatgagcaaa tgtttagtcg tgaaatcaga
     6481 aattgcacag tagggatcat aggaacaggc aggatagggt tgacggaagc tgttttgttt
     6541 aagggactag gagccaaagt gatcggctac gatattcatc agacagaagc tgctaaaaaa
     6601 gtattgacgt tccactcgct tgaagagtta ttagccaaaa gcgatattgt cagtattcat
     6661 gtacctcata tcccaggtga aaacgatcaa atgatcaatg aaggattttt agctcaaatg
     6721 aaaaaaggta gcatcttgat taatacagcc cgtggagagc ttcaagataa tgaagctatt
     6781 ttaagagctt tgaaaagcaa tcatttagct ggttttgcaa ccgatgtttt tgcaaatgaa
     6841 acagaggttt ttttccgatc cttcaagcca tgggagacga ttccagaccc tgctatccag
     6901 caattagtag aaatgtaccc tagagttctt gtaaccccgc atgtaggttc aaatacagat
     6961 gaggcattat caaatatgat ttcgacaagt ttcgagaact ttcgtgaaat aatagaaact
     7021 ggaaaaacga aaaatgaggt atctcttcct aaagcccgtc aattaagata agaaaacatg
     7081 gatattcgtc aataaaatgt ttaaaaatag tccaagtaaa cagttgttac ttctgtatac
     7141 ttggactatt ttgtatggga taattcgatg actcaacagt aatctgtgag ctttttccgc
     7201 ccattctttg tcaattcata acaggttagc ggccggccga tttccaaata tttgattctt
     7261 tcgttcaata tatcttgttc tactaaaaaa ttcaaatatt tcttgacgga tatacgtgac
     7321 agtgagcttt tttgagccag ttcttttgtt gaaaaaatag tatcttcttt tagaataaat
     7381 gcacttattt tttttaaagt cagttttgac agacctttag gcaaatcgat gaatgatggt
     7441 atttcgtgaa tgggagtggt gtggttgaat acttgatcga tcaatttctg atcggctttt
     7501 tcagtcgttt ggattgtctg agagaaagca agatactttt cgatcgccag ctgaaaacgt
     7561 tgcaaagtga acggtttgat caaataatct aaggcaccgt agcggatcac attctttatg
     7621 gtttcgatat catctgcagc agtgatcaaa atcactggga tatcatttcc ttgctgtcta
     7681 agccaagata aaaaatggat accactttcg ccaggcatgt atacatcaag cagcagcaga
     7741 tctgcgtttt tttgtctgaa atattttttt ccttcttcta catttctgaa actttcgatt
     7801 acgttcatat tagggatgct ttccacaaaa gtacgattca attctgcaac cattggatca
     7861 tcttcgatta tcaggacatt tgtcatcatt ttgatcttcc ttttttggta attctagata
     7921 gacgattgta ccgccatttg tttgtttgga aaattctaaa aatccaccgt ggcgtttgac
     7981 gattgaatgg atgagattca atccaaaccc acgattgatt cccttcgtcg aaaaacctag
     8041 cgtaaatatt ttttctgaga tttcttctga tatcccgaca ccgtcatcgc agacggtcac
     8101 gatgaatact tcagcttctg tgtcatagtt taaatgaatc cggacctgtc cgtttctttc
     8161 atgtttttgt agcacggctt cttttgcatt atcaagtaag ttccctaaca cttgcaaaag
     8221 tgaatggatg gagtcatcca tctccatttt agggataaaa gaatcgcttt ctaacagcat
     8281 ttcaacagat tgttctttgg cttcgtttat tttgcctaat aaaaaaccgg caattgcagg
     8341 tactttgatc agacttgaga cttggccaat ctctttttta taattttgat ttagctgctg
     8401 gataaaatgg gtgacttctt catacttctt caaatcaatc aaaccagaaa tgacatgaag
     8461 tttattcatg aattcatggg tttgagctct catggagttt atatattgtt tcgtcccccc
     8521 aagctcctcc attaatttca ttacttctga tcgatttcgt aaagttgcga ctgctcctaa
     8581 aaaacggtca ttgctaaaaa gaggtgtaac gctagaaata gtttctatcc catttaaata
     8641 catggattga gtccgaacgg tcgtttgatg ctcaatcgtc tctttaaaca aaacgtcata
     8701 tagattatca ctgatttttt tcctacttcg aaatccaata gctgctctgt ttggtagaaa
     8761 atgttttttg caggtgtatt gatcaagagg atagttttat cagaagagat ggctaagatt
     8821 ccttcatcta cttcattttc gataatcgtt ttttcactta actgttctgc tatttcttgt
     8881 ggttcaagtc caagcagtac ttttttcatt ttttgggcaa gaaaaacggc gcctatgatg
     8941 cctacgctaa gtccaataat caatgaaaaa acaatcattt tttgtccatc tttgacttga
     9001 ttgtcaatcg tgttgtttgt taagccaaca caaactgcac caataatctc ttgatcataa
     9061 taaataggga cgaaatagcg gaagccgaac cctaacattc cttctttttc agagaaaaat
     9121 tcttgtcctc caatcacttt tttcacatct tcatgacttg agaaaggaag accgatgtaa
     9181 cttgggtctg cgtgagaata tcgaatgcct tcagggtcca tgacaacgat aaaatctaaa
     9241 ttcgatgcaa tcatgatttc atttgttatt ccttgaatcg catgtgtcgg gtcaccagtc
     9301 tgcagctttt tttggatgag tttatcattg gcaacgattt tagcaatgct agagatttta
     9361 tctgacacac tagatcggtt catcgaaaga ataaaattcc tgatcaatat ggcagaaaca
     9421 atcaaagaaa cgaatgtgga gaaacaaacg acaaggatga tcgtgttctg gagctttaat
     9481 ggttttttct taaaaaaagg aaacataggc tacctcgaaa gaatttattg tgaaaatttt
     9541 aacatgaaaa caaaaattta acaaattgtc aacgataaac acaaccttcc tataaaaaac
     9601 accactgagt cggtaaaaga agctatacag aattttcaaa cattggtatg atagacgtag
     9661 aaatggaagg aggcgtgtat atgatagggg gaatcgcact tgagacgatt tattggtata
     9721 cattgctgat ttgtgcagga ttggcagtcc tattgattat ttttggagat gtattcgatt
     9781 ttgatggccc gcttgatccg atgcttatta tcccttggtt aactttcaca agcttatttg
     9841 gttttctagg tgagcgttta acagatcaat catctttatt tttatttatt gctagtggag
     9901 gcatatcgat agtgttggta tttttgctta atttctatat attgatgccg atgaaacatg
     9961 ccgaatcaac gatgtcgtct tctgaaaaaa ctctggaagg acaagtagct gttgtgatca
    10021 caccgatccc tgtacgaggt atgggagaaa ttcagttgaa aagtgttacc ggttccatta
    10081 gtcgtccagc ttgtttttac agcccccaag aacagacagc tgagcgggga acgaaagtat
    10141 tgatcattga gatcaaggaa agaatctgtt atgtcatgcc ttatgaaagc atgataaaag
    10201 cttaaaggag cgtgtgttaa atggaaatac cagttgtttt tatcgcgatc gcaatcgcag
    10261 ctttgatttt actgatgttg ctgatcgtct ttgtagcgaa gtaccagaca gcaaaaccgg
    10321 atgaagcgtt gatcatcagt ggaagttatt taggaagcaa aaatgtgcac attgatgaaa
    10381 gcaataacaa aatcaaaatt gtgcgtggag gtggcgcatt cgtcttgcca gtttttcaac
    10441 gttcgaatcg gatcagtcta ttatcgagta aattggacgt ctccacccct gaagtgtata
    10501 cggaacaagg cgtaccggtg atgtgtgatg gtacttcgat catcaaaatc ggttcatctg
    10561 tagaagagat tgctacagca gcagaacagt ttttaggcaa gacaagagaa gaactggaaa
    10621 atgaagcaag agaagtatta gaaggacact tgcgctcgat tcttggttct atgactgtag
    10681 aagaaatcta tcaaaatcgc gataagttca gtcaaagcgt acaagaagtc gcttctgtag
    10741 accttgcaaa aatggggttg atcatcgttt ctttcactat caaagaggtc agagacaaaa
    10801 acggttatct tgactcttta gggaaaccaa gaatcgccca agtcaaaaga gatgcagata
    10861 tagcagaagc ggaagctcta aaagaaacgc gtatcaaaaa agctcaagca gaaaaagaat
    10921 cacaagcagc tgaattacag cgacaaacag agatcgcaga atcattaaaa gaaaaagaac
    10981 tgaaattagc aacctacaaa caagaacaag atgttgctaa agcaaaagca gaccaagcct
    11041 acaatttaga aagtgcccga gcacaacaac aagtaatcga acaggaaatg cagattaaaa
    11101 tcgtagaacg tcaaaaacaa atcgaactgg aagaaaaaga aatcacacgt cgtgaaaagc
    11161 aatatgattc ggaagtgaag aaaaaagcag atgccgatcg gtacgctaaa gaacaagaag
    11221 cacaagctca aaaagtcaaa gaagttactg aagccgaagc agaacgattc cgtgtggaag
    11281 cactggcaga agcggaagcc aataagacac gtttagctgg acaagcagaa gccgaagcag
    11341 cactagcaaa aggaaaagca gaagccgaag caaaacaaaa gatcgccaat gccttcaagg
    11401 aatatggcga agcagctgtc ttgagtatgg ttatcgatat gctaccgcaa ttgatgcgcg
    11461 aagcagcaca gccgctagga aatatcgaaa aaatctctgt tgtcgataca ggaagcagtt
    11521 caggagaaac cagtggagcg aaccgagtga caaattatgc cacaaatttg ctttcttcta
    11581 ctcaagaaac actaaaagcg acaacaggac ttgacttgaa ggaaatcgta gagaatttgt
    11641 cgacacgtgg gactactagc caagtaaata tgtatgaagc gccaaaagag gcagaacaaa
    11701 actcgatgaa ggaagaataa agtagtacac ttcaccgttc aatcaaaaat ggaggaagac
    11761 tttttaaagt tcttctctcc atttttttat tttattgcaa aagaaaatta gtcctcgcta
    11821 tttttctttt gtttttggat cttagcttct atctcttgta aatttgttct tagcaatcgt
    11881 tctttctttt ggagttcgac caaatcttct gatagttctt ccttcttttc tgtttcagga
    11941 ggacgaagaa agaaattgat accgattgca atgaatgtcc ctataaaagt atctagtaca
    12001 cgttggatag catacaaagc ggattcgcct tgagggatgc tcaacgcaat cagcaacaac
    12061 gtagctattg cggaaatgat accggaatta ttgttaatac catctgacac gacgatcaca
    12121 ataataacta gaataggaag caagatcaat tctaccaaaa aatcattgtg aaaatagctt
    12181 ttgacaaaaa aataaatgat agctaatgta ccacctaatg tattgccgat gatcctagac
    12241 tttccaaaag aaacggttgt agtcaagtcc tgacgcaaag aaaaaacagc agataatgca
    12301 gcaatcatcg ggattcctcg ttgagtcaaa tgaaaaaaca agatacataa aaaaacagct
    12361 aaggcacttt tgatcgtacg catacctagt cgaaaacggc caaattgcat agagattctc
    12421 ctttttggtc tttttactat catacctaaa cttttgtctg atagctagtt tttcattatt
    12481 caagtataat taaaataaaa aagggggaag taaatgcgta taggaatgcg aacagtcaaa
    12541 acagtgatca gtgtcttctt ttcgatggtc acagcgggta gcttatcgct gttgtattgg
    12601 ccagctgcag ggatcattgc attattaagt gtaggaaata ccaagcgctc tacattgcgt
    12661 acgggcatga atcgaatcgc agcctttata ttagctacgg caacagcact gttcagtttt
    12721 tttgctgttg ggtatactat ttttggcttc agtctttttt tattcctgtt catcccgctt
    12781 gcctctcgct tcaaattaac cgaagggata gtagtaaatt cggttttggt cactcattat
    12841 ttagtggagg aaaacatgtc ttggcagctg atcggcaatg aagcgggatt aatggcgatt
    12901 ggattagtat ttgctttgct tgcaaatgtt tacatgccag atcgtacgaa gcagctgaag
    12961 gaaaaccaaa tacagatcga aaaagaattt cgaaatattt tgagacaaat ggcagaattt
    13021 cttttatcag aaaataaaga agatgtgcag atcaaatgcg aacatttact gacattcatt
    13081 cgcgaaagcc aagaagatgc cagagaacat caagaaaact actggctcag acagccgcta
    13141 tactacgaaa cttacttctc tatgagaaga gcacaggcca atgtgattaa agacatgctg
    13201 gaaaatctag agagaatcca gcaaccagct tattatggaa aacatatcta tggtttattg
    13261 atttatactg cagaaacatt ttcagagtca aatgatggca gacaaatttt aacacgtatt
    13321 gaagaagttt atgtattgta tcggcaaatg cctctgccga ctagtcgccc tgaattcgag
    13381 gatcgagcag aattgttcca gtttttgcag tcttttaaaa gttttattga aatcaaggca
    13441 gaattctccc aacaaaaaat ccaaaaatag aggttgtgaa ttcagctaat attcaggtca
    13501 aaaagctgat ttcacaacct cttctttaaa cggtgttctc ctgtcaactc ctcggtcaca
    13561 agtcacaata ttcaacaaac atgagaagct gttttttgaa attgctcctt gtgactcgga
    13621 gctgaacggt aggctcacaa cctctttctt aaacggtgtt caaaagcttt cctctgcggt
    13681 aataagtcca gccaaacgaa aaataggagg agctattttt gtttggctgt tcttattact
    13741 tgatgcagaa cagctttttc acaacctttt aaaattacat atttttccat agaacttgca
    13801 tttgatccaa gatttcgatg acatcttttg tcaagaagag agagcgattg ggcaagtcac
    13861 cttcaatcat gtgtaccata ttctttattt cgtaattcat tgcttcagat gtattcccgc
    13921 tttcgatgaa ttcctttgta ccatctgtaa ataagatctc cgcacgatca gcacgcgggt
    13981 aatcagcaat cgtcacataa ccgttctcaa aggcaacgat accgactttt ggcatttttg
    14041 cctgaaaagt caagctgaca gcagcaagtt cattttcttt gttacgcaag atagtgacgg
    14101 attgttcgtc cacgcctgtt tcaaaaggaa ccattgtaga ggcaactact tcaggttgag
    14161 agctcaaaaa gaaacgagcg aaagatacag catacgtacc gatatccaac agagctcctc
    14221 cagctaattc tggattgaag aaccggtttt tagggtctgg ttctttgtaa ctgccgaaag
    14281 gtgcttggat catttttaaa gcccccagtt ttcctgtatc cattattgag cgtaactgct
    14341 gataaagtgg catgttgaag attgtcatcg cttctgctaa gatcaaattc ttttcttctg
    14401 ctaagcgcat agcgtcagcc agttcttttt tattcatcgt gatggctttt tcacatagaa
    14461 cgtgtttgcc tgcttccaat gctgccaaga tatggtcgat atgctgtcta tttggtacag
    14521 caatgtacac gatgtcgatt tcagcatcgt ctaacatttc ttgatagctt ccgtaagctt
    14581 ttggaatatt gtaacggtga gcgaagtttt ccgctttttc tgaagttctg gaagcaactg
    14641 ctgttagttc gctcgtctct tgattgaagc tttcggcaaa ctcatgtgcg atggtaccaa
    14701 gaccaacgat tccccattga tattttttca tctgaaaacg ctccttcata gttggattga
    14761 gtttcttgtc tgtctattat tataacaaaa atcacgaaga ataaagagga gaggacttga
    14821 aacattaaaa aaaatgaaag cagcgattta agaggtgctt tttgatcaaa acttaagtag
    14881 aatagttaaa aggaggggat aaacgtgcat caagtatata ttgatcttat tatgagtgta
    14941 ttattagaac agtttgaaac tgaaaaaaat tttttagatg aatacttgct gatcagtcca
    15001 gaacaatggc aaaaatggaa agatggcgag aaaaatctgc catctgaagc gatgcagaaa
    15061 gtaaaaaatc ttttcactga ttatgaatgg atgctaacgc aaaagatttt gcgtcaaacg
    15121 attatttttc ccgaaaaacg aaacgttgcc gttgcagagt acaagcaaat caaaacacgc
    15181 atcgcgcaaa aatggcttag cagcaaagca gcaaaagtcg agctgatccc tttgaaaaat
    15241 aatcagcagg ctggtagata ccttgacttg aaagtaagta ttcaatatga tgaatggggc
    15301 tatgatgata ttttgaattt tcgtctgcca gcagatgttc aaaaacagat cgaaggagaa
    15361 aaaatcgaac ttctcgattg ggtgaatgaa aatctggaag aaacttacgt tcatgaggcg
    15421 aatggggaac gtgaagaaca acgaaaggat ttttcaagtg aataaatttt taggatttgg
    15481 agcagttgtg attatgatcg cagcaatggg ctatgttatt tttagcgatg atgattcgca
    15541 tgttcaagcc ggcaatcaag cagtcgaacg aacaagcacc aaaacaactg ctagtaaaga
    15601 aaagaacagt caaacaacca gcagcaaggt aaaggacaaa gaaacaaaag atcgtacgtc
    15661 caaacaattg ccagatgtta aaacagacga ttggaagcta gttttggttg gtccagatca
    15721 caaattagaa aaagaaattg atgagtctac tcaattggca tcattaagta acggatactt
    15781 gatcgacaaa cgcattgctc cagaatatga agcatttgcc aaggctgctg aagcagctgg
    15841 atttccatta gtgatggtct cagcttaccg gtctgtatca tcccaacaac aagttttcga
    15901 acaaaatgtc caagatgtga tgagtcgtca aggtgtatca gaagaggagg cgacaaagat
    15961 tactaaagaa acgattacgg agccaggata cagcgaacac cacacaggtc tggcagtcga
    16021 tgtcgtcgat caaaactggt acaacagtta tccttctact gtattggatg caagttacgg
    16081 agatcagcct ggagctaaat ggatcgcaga taatgctgcg cagtatggat ttatcgttcg
    16141 ttatccaaaa ggacacgaag atataactaa gatcacatat gaaccttggc acttacgtta
    16201 tgtcggtaaa gaaaacgctg agtatatcac caaacaccaa ttgacgctag aagaatatct
    16261 gaatgaatta aatgaaaagt aggaattgat catggcgaaa aaaaagtgga aaaagcaaaa
    16321 gcgcaagaat atccgttggc cagcagtggt tgccggtgta gcagtgatac tcttagcctt
    16381 tgttttttcc ttgaagaatc tgtcttctcc ttttactgat aatcagcaag aaaatgaagc
    16441 gcaatcccat cagcaattta ttgaacggct tgttccgcat gcccaagaac tacaagatgg
    16501 ttatggagtg cttcctagta tcattttagg acaagctata ttagaatcaa attggggaaa
    16561 aagtaccttg gctagcaaat acaataatct tttcgggatc aaggcttatg gggatcagaa
    16621 gaaagtaagc ctggaaacaa aggaatttgt taacgaagaa tggataacta tccaaggaga
    16681 cttcaaagtg tatgattcat gggaacagtc catggatgac catacacaac tgttcgtcca
    16741 aggagtagat tggaatcctg cgctgtatga aaaagtgatt acggccacca actatcagga
    16801 agccgcacaa gcattgcaag atgcaggtta tgcgacagac cccggttatg cgcaaaaaat
    16861 catccaggtc atcgagacgt atcaattgaa tcagtatgac cggagatagc aaaggagaag
    16921 tggctgatgg cagaacaatt tacgccagaa atcatgacgg aattgagaaa agatatcgta
    16981 agagtaccgg aaatcatttt agaagcaagc gggatcaaga tatttggaaa attgatccgt
    17041 tcgatcatct ttactacgga tattgcgatc atacgtaata caaatgcgaa tgcagtaatt
    17101 gctgtgtatc cttttacacc tcatccagcg attactaaaa gcattattga ggcagctgac
    17161 attccagttt tctccggtgt aggtggtggt ttgacacaag gtgctcgttc ttcctacatg
    17221 agcatgttcg cagaagcgca aggttcgtta ggggtcgttt tgaacggtcc tacgccttta
    17281 gagacagtaa aagaagtttg tcgagtagtt gatattccag ttatcagtac ggtaacgtcg
    17341 aaatatacag aaatagatga aaagttagca gctggtattt cgattatcaa tatcagtgca
    17401 ggtaaagaaa ctgcagaagc agtacgccat tttcgtaaaa aatatcctga acttcctatc
    17461 attgcgacag gtggtccaac ggaagaaagt attgctgaga ccattcaagc aggagcaaat
    17521 gccatcacat atacgccacc aagtagcgga gagcttttta gtcgtaaaat ggaaaaatat
    17581 cgggaaactg agaaaaagaa tcatgaataa caggtgagaa tcaaaagacg aggaagagca
    17641 gatagtggct cttcctcgtc ttttgtactc cagtactatt tgttcagaat tcaaaaaaaa
    17701 gagaaatttt tttgtttttt tacctgtaat gtacataaga agagttaaaa ccttttgtta
    17761 ttattagcat tctaacaaaa aaatgtcttg atttattgaa gcgctttcta tagaatgaaa
    17821 aacgaataaa aactaaaaaa ggcacccgac aatttagtag cagctaaatt gtcggggctt
    17881 gaaaagtcag cgggaactga ccaatcaagt tgccatagtc aatgcttgtg catcgacgtg
    17941 tatattgtac ctaatttcat acagaattac tagttatttt tctgtttttt agggaagagc
    18001 gcacacgaag aagcatgctt atttagctat gtcaaggata ttgggcagtt gtctgatatc
    18061 cttttttctt tgcgtaatta tcctcccatc attgaagcaa gaagtgtttt tagcgatgaa
    18121 agaagaatca gcactatcta atttttcttg aaagtattga gttgttcatc ctaggcagaa
    18181 cgataaggca agtcttggtt tttattcccc ttgaaaaaga tcgtttaata aatatgttct
    18241 gtataaaaat acagtatatt gaaaaataac aatggaagta gaggtgcaga gaatgaagaa
    18301 aagaatgaga atcatcttag ctttaagtgt tatgttattc ttcttgacgg cttgtgggca
    18361 agaagatgac aaaaaaatca cgctgaacat ggcttggtgg ggttcgcaag tccgacacga
    18421 tgcaacagta aaagtaatcg agctttatga agaaaaaaat ccccatgtga cgatcgatta
    18481 tgaattttat gattatgaag gatattacac aaaattaggt acactagcag catcagatga
    18541 tatctgggac attttccaac tgaacaatca atttcctcaa tacatcaatc agattgaacc
    18601 attagatgaa tatgtggagc aagggataat tgatatttct aatgcagatg aatcctattt
    18661 agcaacgacg acttacgacg ggcaattagt tggactgtct aacggggtga attcgtttgc
    18721 gattgcttac aataaaaata tatttgaaca attaaatatc cctgaaccag cttcaaattg
    18781 gacatgggat gaatttgaac aaatcagcta tcaaatcact gaagaattag gaatctatgc
    18841 tatttcaaga ttcgaagatt ttatagctgg ctgtattatt caaataccac aagttgagaa
    18901 aggattgaat ttttataatc gggaagatct atctaacagc ttgggatttg aaaatccaga
    18961 ctatctaaca gattttttcc agctgcgtaa aaatctggta gacaaagggg cccatccaga
    19021 accaggtggt ggagctgcaa gtacgacgga tctgtctttt caggcggtta gggatagaga
    19081 agcggcaatg gtgtttctat caagtaacca gttgacagaa atattgtcag gggctcctga
    19141 agatatggag attcagttga ttaatccacc tcgcagaaaa gcagatggag aatctggtat
    19201 ccctttacgt tcttcgcaaa tgctgagtat ggcaaaaagc tcagcccata aagaagaagc
    19261 tgctaagttt attgatttct ttcaaaacag tgaagaagcc aatgaaattt taaaaggaga
    19321 acgtggtgta ccaatcatgt cgaatattcg agaacagctc gctcgtgcag atgatgcaac
    19381 tttgcaagcg acatttgatt atttagaaat gatttccgat atggacaacg gcgaagtgaa
    19441 tgtctttgat agtgctttga atccggaaat tcaagaccaa tacaatcttt tagttgaaaa
    19501 agtcatttat gaagaagtaa cagcagaaga agcagcagag agtctttatg agtttgcgtc
    19561 aaacattcta ggatagcagc aggaggaagg catgaaaaaa gaaaaactaa aacggttctt
    19621 ggatcaagac aatgtggtcg gttacgtatt tgcttctcca ttcatcctag gatttctatt
    19681 gataacagtg ataccgatga tcttgtcact ttattattcg ttcaccgatt atcgtttggg
    19741 aaatccagtc tcatggatcg gcttggataa ttatataaag atgctgagtg atgcccgttt
    19801 tttgaactcc atccgagtca cttttctcta tgtatttgca tctgtacctg tgaaactgat
    19861 ctttggtcta ttgattgctt atcttttaac gaggaatatc aaaggaacga ctttctttcg
    19921 ttctttgtat tatgtgccta gtttgatcgg tggcagtatt tctatcgctc tagtttggcg
    19981 ggagttgttt tctaaaaacg ggttagtgaa tattttcctg gaacgattag gcgcacctgc
    20041 gctttcctgg tttagcgatc aaaaactggt catgatccct cttgttttga tgtctgcttg
    20101 gcaattcggt tcggcaatga tcatctttgc tgcaggtatc aaagagatcc caggctcgta
    20161 ttatgaagcg gcagagatcg atggagcgaa caaatggcag acgttttaca agatcacgtt
    20221 acctcttctt tcgccgatca ttttgtataa cttggttatg cagacaatcg cggcgtttat
    20281 gacttttacg caggcattta tcattaccca aggtggtccg aatgatgcca cgaactttta
    20341 tgctctttat gtgtataacc aagctttttc ttttaattct atggggtatg ctagtgctat
    20401 ttcgtggatc atgctgttga ttatgggagc tgtcaccttt ctgattttca aatcatcaaa
    20461 aaaatgggtc gttgtgtgaa tgagaggagg aagaaatgaa taatacagta acgaaatggt
    20521 ttcaatacgg ttttattttg ctattaggtc tagtcatgat ttatccggtc ttatggatga
    20581 tcgcaggttc ttttaaaacg gatcaagaga ttatgagtgg ttcgctgaat ttgattccag
    20641 agacttttca atgggaaaat tacgcaaaag gatgggcggg gtttgctgga atttcatttt
    20701 ttactttctt taggaattcg tttgtcatct ctgcagtttc gacgataggg acagttctga
    20761 gctcgacttg tattgcttac gcattatcga gaatcgattt caaaggaaaa agattctggt
    20821 tcgtcgtcat gttagtaacg atgatgattc ctgcacaagt gattttgatt ccgcagttta
    20881 ttatttacaa tcggctgaat ttggttggga cgtatgtgcc gctgatttta ccacattttt
    20941 ttggacaagc atttttcatt taccagatca tgcaattcat ggtcagcatc cccaaagagt
    21001 tagatgaatc agcgattatt gacggatgca gcaagtatag tgtctttacc aaaattattt
    21061 ttcctttgct gaaaccttcg atcatcacga cgatcatcat ccagttttat tggaaatggg
    21121 acgacttcat gggaccattg atttatttaa acaagccgag atcttacacg gtatcgattg
    21181 ccatcaaatt atttgcagac gctggatcta gtacgactta cgcgagtatg tttgcgatgt
    21241 ctacgttgtc gctgctaccg gtttttctga ttttcttatt cttcaataaa tatcttgtcc
    21301 aggggatcag tacaagcggt ctgaagggct gaatatgaaa aagccaatag aagagatgtt
    21361 tctttacaag ctcaactact atgtctgtcg gattttttta accagtctta tcagtaatgc
    21421 tcttttcgct ttagttctag gatgtttgtt cactttagga ttagtgctgt ctgctcgtgt
    21481 tgtctatctg atttattttt tgatgatgta tccttcttat tatctatctg tccattactt
    21541 ggcagaaaaa aaggtatgtt ggaggaaagg aaaaatcaaa cggatgtgtt tcatcattac
    21601 gttgtttcag ctgtttgtca ttatttttgc agttgattgg tatttattag tgggaaagat
    21661 tggagcttgg tatctgattc cttttctatt gtgtctgttg ctttttgtat cccatagttt
    21721 ttttagtacg ctaattgata tctgcaaaga agataaagca gatagtcttg tttatttgat
    21781 caaaaggaat atctggctgt tgtcaaaaaa cgtcaagggg tttctgtggt atttatgcct
    21841 tttgtatgga ctgttctggt gtatacagca tgatttttta ctcactgcat tactgtatcc
    21901 agggctgcca tttgtcacag tattttgctt aaaagaaaag gagaatgact ttaaatgaag
    21961 aaaaaatatg tacaagtcgg acttggtggg agagcgcgtt ttttttatga ggcaattgcc
    22021 tctacgtatc atcaaacttg tgaactagtc ggtttttgtg atgtatctca aacaaggatg
    22081 gattatgcaa atcggatact tgtgaacaag tatggacaga aaaaagtaaa gacatgtatg
    22141 ccatcacaat ttgagcaact actggatgac gtacggccgg ctgaagtcat tattacgtca
    22201 gtagatcgaa cgcatcatga ttatatcatt cgtgcaatga aaaaaggata tgatgttatt
    22261 tgcgaaaaac ctctgactat cgatgaggaa aaagctcaag aaataataac ggtccaaaaa
    22321 cagacgggaa gaagcctgcg agtcactttt aattatcgtt atgcaccgta tcacacgaag
    22381 ataaaggaac tgatagaaag tgatgtgatt ggtgatgtgt tttctatcca cttcgaatgg
    22441 ctgttaaata cgcaacacgg ggcagattat ttcagaagat ggcatcgaaa taagcacaat
    22501 agcggcgggc ttcttgttca taaatctacc catcattttg atctagtgaa tttttggttg
    22561 aacagccgtc cccaaaaggt atttgcattc ggtggattaa acttttatgg gatgcataat
    22621 gcggagaaac gcggagtaga aatattttac agtcgatgct atggaagcga actagctaaa
    22681 gctgatccat ttgctataga cctgtcagcc aatgaggaat tgcgagaaat gtatttagaa
    22741 gcagaaaaag acagtggata tattcgtgac cgcagtgtat tttccgatga tatctctatt
    22801 gaagatacac taggcgtaac ggtcaaatat gaaactggtg cgattttgac gtattcgcta
    22861 aacgcgtata tgccgtggga aggattcaat gtttctttca atggcagcaa aggacggatc
    22921 gaaatgaaag tgatcgaaaa gtcttacatc aatgcaggtg gagataaaaa ggatgaagga
    22981 gcagccgttc ttcagtccat ccatgtctat ccgatgttcg gtgagccata tgaggtaatc
    23041 gtcgaacaag aagcgggcgg acatggcgga ggagatccgc gtttattaga tgatctattt
    23101 ggtgaagaaa aagaagaaga tccgtggaat cgggcagcaa ctcacgtaga tggtattttg
    23161 tcgattttga caggaatcgc agcaaatcat tctattgctt caggaaaagc agtagtgatt
    23221 gacgagcttg tcagcttaaa agaataagaa tagatttacg gaaattactt cccgtagttt
    23281 ataaaatctt gccttattgc cgataggctg tcttttgaac actatttatt cggaaaaagg
    23341 ggctatgaca tgctttttgt catgccttct ttttatgtgg gctgcttttt tagataggag
    23401 aaaataaaaa taactattta aacccgaaca aaaaggaata atgcattaaa aatcattaga
    23461 ttttacaaaa aaataagtaa accacgttgt cagtttcaga aagtagtgtt agactgtttt
    23521 caatatttga aacaacattt tttattcaaa tatggcaaac tgccttcacg tgcaaaacag
    23581 ttgcaagaaa atgaatttac actattatta gttttacata cctacttata tatcgtcata
    23641 atatggatga cagtttctag ccagtaccgt aaatgctgga ctataagtaa aagattggct
    23701 atttcaccct tcttttctta tgataaagtg gagggtgttt ttctttaaca gaaacatagt
    23761 aggtttttgc acaaaagcgg ttatttcggt attaataaat gataaaggag caaataaagt
    23821 gaaagaatta gttgaacgta ttcaaaaaga cggacgtata ttaggcgagg gcgtattaaa
    23881 agtcgacagc ttcgtcactc accaagtaga ccctgtattg atggaacaaa tgggaaaacg
    23941 gtttgcagaa gtatttaaag aacaaggaat cacgaaagtt gtgaccattg aagcttctgg
    24001 gatcgcacca gctttatttg ctgcaagaga attagatgtt ccaatgatct tcgctagaaa
    24061 agcaaaaagt ttgacgatgg atgaagaatt attgacagct tctgtttatt cttttacgaa
    24121 acaagtgaca agtacgattt ctatttctcg taaattttta tcttcagaag acaaagtatt
    24181 gattatcgac gatttcttgg caaacggaca agcggcaaaa ggattgatcg aattatgcca
    24241 gcaagctgga gcgcaagtag aaggaatcgg gatcgtcatc gaaaagtctt tccaagatgg
    24301 acgtcagtta cttgaagaaa tgggattgag agtcgtttct cttgcgcgta ttgcttcctt
    24361 gacgaatgga caagttgagt ttcttgagga ggacgcataa tcgtggaaaa agaaacacaa
    24421 aatggaaaag ctgcggtttt agggctgcag catctgctag cgatgtatgc aggagcagta
    24481 gcggtgcctc ttttgatcgg tacaggacta ggctttaatc aagaacagat gacttatttg
    24541 atttcaattg atatctttat gtgtggatta gcgacattat tgcaattgac agttaaccga
    24601 tttttcggaa ttggcttgcc tgtcgtttta ggatgtgcga tccaagcagt agctccactg
    24661 atcttgatcg gaaccaatga aggagtagga gctatctacg gatctattat cgcttctggg
    24721 atctttgttg tgttagtttc tggtgtcttt tctaaaatta aaaaactatt ccctcctata
    24781 gtaacaggaa cggttatcac cgttattggt ttgactttga ttcctgtagc aatcgagaaa
    24841 atgggtggag gtaatgcaac agcagctgat tttggtgaca aaacaaatct gctacttgca
    24901 tttgtgacga ttctcctaat tgtaggcgtg caaatgctgg caaaagggtt cattcgttca
    24961 atcgcggtat tgattggttt agtcggagga agcatcttag ctgctttcat gggaatgatt
    25021 gatctgagcg cgattggaga tgcgccgttg ttccatgttc cacaaccctt ttattttggt
    25081 aaaccaactt tcgacgtatg gtcgatttta ctaatgatca tcatttccat ggtcagcatg
    25141 gtagaatcaa caggtgtata ttttgcactt ggtgacatta ctgggaaaaa tgttggagaa
    25201 gaagaattga aaaagggata tcgtgcagaa ggacttgccg ttatcttagg cggtattttc
    25261 aatacattcc cttatactgg cttttctcaa aatgtcggat tggttcaact ttcgggaatc
    25321 aaaacaagaa aacccatcta tttctctgca ttcttcttga ttgttttagg attattccct
    25381 aaaatcggtg cgttagcaca aatcatccct gagccggtac ttggtggagg aatgttagtc
    25441 atgttcggga tggtggcagt ccaaggaatc cgtatgctgt tggaagttga tttcagcaat
    25501 gataaaaatc tattgattgt tgctgtttct gttggatttg ggctgggttt caatgttacg
    25561 ccgacattat tcagtcaaat gccgcaaaca ttgcaaatgt tcactggaaa tggcatcgta
    25621 atgagtagca ttacggctat catattgaat ttgatcttta atggattgaa aaaagatgaa
    25681 gaaatattgg aagaagcctt caagaagtaa tagagcaaaa gaaaggttgt gaaatcagcg
    25741 ttttgacctg attgttagag aaacaaacgg aaaaatagtt cctcgtattt tgccgtttgt
    25801 ttgagctaat accgagggtc agctgattga acaccgttga aggaagaggt cgtgagcctg
    25861 ccgttcatct ccgagtcaca aggaacaatt tcaaaaaaaa gcttctcatg tttgttgaat
    25921 attgttcctt gtgaccgagg agttggcagg agaacaccgt ttatccataa aaaggaatgt
    25981 gacctaactt ttgtcacatt cctttttttt atctttaata aacacgaaca ataaaatgtt
    26041 tttctttgtt aacattcgaa atttctttga catcaaaaaa agtgattgtt aaaatatgaa
    26101 tgtagaaaaa ctgggaggaa aaacaatgac agcaaaaatc tctgtgatta tggggagtac
    26161 ttcagattgg gaaacaatga aagaagcatg tcaaatattg gatgaattcg gtgtgtctta
    26221 tgaaaaaaag gtcgtttctg ctcatcgaac cccagatttg atgtttgaat atgcacaaaa
    26281 cgctcgaaaa aaaggaatca aaatcattat tgcaggagca gggggagccg cgcatctgcc
    26341 gggtatggtc gcatcaaaaa caactttgcc ggttatcggt gtaccggtcc aatcacgaac
    26401 attaaatggt ttggattcgc ttctttcgat tgtccaaatg cctggaggag tacctgtagc
    26461 tactacagca atcggaaaag cgggagcaat taatgctgga ctacttgcga tacagatgct
    26521 ttccatgtat gatttagaat tggaggctaa attggctgaa agacgttcaa tgttggctaa
    26581 aactgttata gaaagtagtg atcaacttgg ttaaaccttt gttgcctggt tcaacgatcg
    26641 ggatcgtcgg tggcggtcaa ttaggtcgta tgatggcgat tagtgcaaaa gaaatgggct
    26701 ttaaagtagg tgtgctggat cctgtgagcg attgtccagc cgcacaagtt gcagattggc
    26761 acattgaaag tgtctatgat gacacctttg cgctgaaaga gcttgccaga agaacagatg
    26821 tcattaccta tgaattcgaa aacgtcagtg tagaggcgtt aaatgcgatt ttacccatgt
    26881 catttattcc tcaagggaca gacttgcttg cgattacgca agaccgcctg ttagaaaaat
    26941 cttttttgga aacgaataac atcgtgattg ctccttatgc aacgatcgtc agtccgacgg
    27001 atatccaaga tgcgattgac gggatcggct atccttgtgt tttgaaaacc actcgaggcg
    27061 gctatgatgg caaggggcag tatgttttga aaagtcgggc ggatctagct cctgccatgg
    27121 accttttaag agaaggaacc tgtgttttag aagcatggat cccgtttgaa aaagagattt
    27181 cgatcatggt ggcaggaaat ggtcaaggag atttcacgac ttttccggtc gtggaaaaca
    27241 tccaccacaa caatattctt catgaaacga ttgctccagc cgcgattgat caggatgtga
    27301 tcgaggaggc tgagcgtatt gcccgtgtga ttgcagaagc agtgagcctt tcaggtgttt
    27361 taggggtaga aatgttttta acaaaaacag gcgggctata tgtgaatgaa ttagctcctc
    27421 gtcctcacaa ttctggacat tattctattg aagcttgttc tatgagtcag ttcgatgccc
    27481 atattcgagg tatttgtggt tggccattag gagaaaaagt acgtttgata agcaatgcag
    27541 taatggtcaa tgttttggga gaacaactgc tggaaagcta tcgcttgatt gagaataagc
    27601 cagactggca attccatttc tatggaaaaa aacaagcaaa aaaaggtcgc aagatgggac
    27661 atatcactat cttgacagaa gacatccagc aaacgctgga agaaatcaaa caaacgaata
    27721 tttgggatta gaggagaaaa aacatgttag aacgttatac acgccctgaa atggggaata
    27781 tctggacgga agagaacaaa taccgtgcgt ggctcgaagt cgagatttta gcagatgaag
    27841 cttgggcaga acttggtgaa atcccgcaag aagatgtgaa aaaaattcgt gagcatgcat
    27901 catttgatat cgatcggatc ttggaaatcg aaaaattaac acgccatgat gtcgttgcgt
    27961 ttacacgagc ggtttctgaa acattgggag aagaaagaaa atgggtccat tatggtctaa
    28021 caagtacgga tgtcgtagat actgcttatg gctatctcat caagcaagca aatgatattt
    28081 tacgggaaga cttgaaacgt tttacggaaa tcattggcga aaaagcaaaa gaacacaaat
    28141 atacagtgat gatgggtcgg acacacggtg tccatgctga accaactact tttggattga
    28201 aacttgccac atggtattca gaaatgaaac ggaacatcga acgatttgaa catgcggcaa
    28261 aaggagtaga agcaggaaaa atctcaggag cagtgggaac gttcgcaaat atcccgccat
    28321 ttattgaaga gtatgtatgt aaacaattgg ggatccgtcc acaagaaatt tctactcaag
    28381 ttctccctcg ggatctacat gctgaatatt tctcagcgat ggcgcttatt gctacaagta
    28441 ttgaacgttt tgcaacagag atacgcggat tgcaaaaatc cgaaacacgt gaagtagaag
    28501 aattttttgc gaaaggtcaa aaaggttctt ctgctatgcc gcacaaaagg aatccgatcg
    28561 gttcagaaaa tatggctggt ctagccagag tggtgcgcgg acacatggtc actgcctatg
    28621 aaaatgtcac attatggcat gaaagagata tttctcattc ttcagcagaa cgaatcatct
    28681 tgcctgatac cacgatttta ttgaattaca tgttaaatcg ttttggcaat atcgttaaaa
    28741 atctaacggt ctttcctgaa aacatgaagc ggaatatgtc tgcaacattt ggtttgattt
    28801 atagccagcg cgttatgctg aaattgatcg ataagggaat gacaagagaa gaagcttatg
    28861 atcttgttca gccaaaaact gcgtacgctt gggacaacca agtgcagttc cgcccgctgt
    28921 tagaagaaga tccaaccatc acatcggtat tatctaaaga agaaatagac gatgcctttg
    28981 attatcatca tcatttgaaa aacgttgacg tgatattcaa acgagtaggt ttggaataaa
    29041 gaagagtgag ttgcaaaatt caattaaaat agaatagcaa aaataaccaa aaaagaagca
    29101 gatccgttag cggttctgct tcttttagtt tattatattt tcttatcaat aataggaacc
    29161 tgattttaaa agcggctacc tctttaccgt gcctctttac atacaaaaaa tagaggaatt
    29221 aagcgtaaat ggcttggcta ttataactaa aatgctggtt atggagatgt tgcagcaagt
    29281 tttcgagaaa agcgtattcc atctcttgtc cattgaataa gatctggata cgataatgat
    29341 ttttgaaacg cttctgttca tgaatctgac tgattgaaag ttcgcctttg tgttctgtct
    29401 gataaagaaa agtcctttta cggcattcag cacagcgctt ggttgctcgg cggatttttc
    29461 ggaatgtata aaaactagta tctttattgc ataaataaac gtctttgatc gacagcaaat
    29521 cattatatag acaggaacgt tcttcagctg ttaattctga taaaaaaagc tgaccttgtt
    29581 ttattgcatc ttccatcggc aagtgcctcc tcgaacccat tatccaaatt tttagttaat
    29641 tctaatatac catcattaag tataaatgta aacgcttgtt gatggtataa gattttcgtt
    29701 tctgataaaa cacgaacatt aaaagaatct aatgccttaa atgtacatat ttttgttgat
    29761 ttataaaaag atgattgcta aaatttaaag tgaaaaaacg aacaaaaaac gatgtatttg
    29821 cttttaatgt aaataaaaag gagagacgta catggagaag aaagaacttt tgtatgaagg
    29881 aaaagccaaa aaaatatatc ttacttctga tgagaacttg atttggatag aatatttaga
    29941 tcaagcaact gcgttgaatg gcgcgaggaa agaccagata agtggaaaag gagaattgaa
    30001 taatcaaatc acaagtgcaa ttttccgtta tctgactcaa agaggaataa aaaatcattt
    30061 tattgaacaa ttgtctaaaa ccgaacaatt agcaaaaaaa gtacaaatta tccctctgga
    30121 agtggttatc cgaaatattg cagcaggaag tttctcaaaa cgtctaggtg ttcccgaagg
    30181 taaagaattc atcaaaccaa tcattgaatt ctactataag gatgaccagt tggatgatcc
    30241 atttatcaat gaagagcata tctatttctt acaacttgca aagccggaag aaatcagtga
    30301 gctgaaagcc caagcgttgg ctattaatga aattttgacc gaattatttg ctaaggtcgg
    30361 tttggtttta gtagatttca agctagaatt tggccggtcg aatggacaaa ttttgcttgc
    30421 ggatgaagta acaccggata cttgccgatt atgggatgaa cgtacgaatg aacatatgga
    30481 caaagacgtt taccgcagag atctaggtga tttgatccca gtctatcaag aagtatataa
    30541 ccgtctatcg gaactaactg aagaaaagga gcgagtatga tgtatttcgt aaaagtatat
    30601 gtaacctata aagattcagt gttagatcct caaggggagg cagtaaaaaa agcagtccat
    30661 cgtatgggat atgaaacaat cgaagatatc cgaataggaa aatactttga gatacaactt
    30721 gctgatgcag aagaaccaat cgatacagtg attgaaacga tttgtgacaa gctgcttgca
    30781 aatgtaaata tggaaacata ccgatatgaa atcaaaaaaa tggaggaagt ataacatgaa
    30841 atttgcggtc atcgtttttc caggttcaaa ttgtgacgca gatatgttat gggcagttcg
    30901 cgagatcatg ggcgctgatg ccgaatttgt acggcatgat gagtcctctt tagaaggatt
    30961 tgatggggtt ttactgccgg gaggattctc ctatggtgac tatttgagat gcggtgcgat
    31021 tgctcggttt tctacaatca tggaagaagt gattcgtttt gctgaagaag ggaaaccagt
    31081 attcggtaca tgcaatggat tccagatatt gacagaagca ggacttttgc caggtgtact
    31141 gagacgaaat gagtctttgc attttatttg caaaactgta ccattgaaag tcaaccccaa
    31201 gacggccttt acttcagagt atgaagccga cgaaataatc tatcttccag ttgctcatgg
    31261 ggaaggaaat tatttctgtg acgaagaaac acttcaagaa ctaaaaaaaa ataatcagat
    31321 tgcctttact tataatgaca acatcaacgg cagcgtggaa aacattgcag ggattacgaa
    31381 caaagcaggg aatgtgttag gaatgatgcc tcatccagaa cgtgcagtag aagacttgct
    31441 aggatcagaa gatgggaaac ggttctttgc ttccatttta aaaaacttcg gaaaggtgac
    31501 cgtatagatg aaaacattga aagaaccgac agctgaagag atcaagaaaa aaagaatcta
    31561 tgccgaatgg ggattgactg atgaagaata tcgaatgatc gaagaagata tcttaggaag
    31621 aatgcctaat tatacggaaa ctggactgtt ttctgttatg tggagcgaac attgttccta
    31681 taaaaattct aaaccggttc tacgcaaatt tcctactagt ggacctcatg tgttgcaagg
    31741 ccctggagaa ggcgcaggca tcgtcgacat cggtgatgga ctagcagttg tcttcaaagc
    31801 agaaagtcac aatcatcctt cagccgtgga gccttatgaa ggagctgcga caggagttgg
    31861 cggaatcatc agagatattt tcagcatggg ggctcgtcca attgcgttgc tagattcatt
    31921 gaggttcggc gaattagata atccaagaac gaaatattta ctagaagaag tagttgcagg
    31981 tatcggcgga tacggcaatt gtatcggcat accgactgta ggcggcgaaa ttgcatttga
    32041 tccttgttat gaaggaaacc cattagtcaa tgcaatgtgc gtaggtttga ttgaacacaa
    32101 acatatccag aaagggcaag ccgctggcgt cggtaattcg atcatgtatg taggtgcaaa
    32161 aacaggtcgc gacggtatcc acggagcaac ttttgcctca gaagaattta atcaagaaga
    32221 agaacagcaa cgttctgctg tacaagtagg cgatcctttt atggaaaagc tgctgcttga
    32281 agcgtgtttg gaattaatct tgcatcattc ggattctcta ataggtatac aggatatggg
    32341 agcagcagga cttgtttcat ctagtgcgga aatggcttca aaagctggct caggacttat
    32401 attgacatta gatgaagtcc cacaaagaga aactgggatg acaccttatg aaatgatgtt
    32461 atcggaatca caagaacgga tgttgatttg tgttaaatca ggagaggaag aaaaaatcca
    32521 agaactattt cagaagtatg atctagatgc agtcactatc ggtaaagtaa cagacgacgg
    32581 gcaatatcgg ctatatcatc aaggagaaga agtagcaaat ctgccagtcg atgcattagc
    32641 tgaagatgca ccagtttatc ataaagaaat gaaagaacca gctcgaatcg tagaatttca
    32701 gcagttagct ccttatcagc cagttatcga agaacctgga caagtattgc ttgatctgct
    32761 gcagcaaccg acgattgctt caaaacgttc aatctacgaa acttatgatt cacaagtaca
    32821 aaccaataca gttgtccgtc caggaagcga tgctgctgtg atgagggtta gagggacgaa
    32881 taaagcgtta gctatgacca cagactgcaa cgcgcgctat ctgtatttgg atccaaaaat
    32941 cggaggacaa atagcagtgg cagaagctgc tagaaatatt attgctagcg gtggtaagcc
    33001 cttggcgatc accgactgcc tgaactatgg ttctcctgat aaaccagaag ttttttggga
    33061 attatcgact tcagctgacg gaattgctgc tgcgtgtgaa acgttaggaa ctcctgttat
    33121 ttcaggaaat gtctctttat ataatgaaac ggatggtcaa gcaatctatc caacaccaat
    33181 gattggtatg gtcggattga ttgaggatca taaacatatc actactcagg aattcaaaaa
    33241 atcaggggat ctaatctata tattaggtaa gacgtttgca gattttgatg gcagtgaatt
    33301 acaaaagatg cagcttggaa gaatcgaagg tgtgatccga aactttgatc tatccattga
    33361 aaagagaaac caagagttag tattgacagc catccaaaac ggattgattg aaagtgctca
    33421 tgactgttca gaaggtggct tggcaattgc actggcagaa tcagctttca aacatcagct
    33481 agggatatct gtacagtttg aattgtcctc tgctcaatta tttgcagaaa ctcaatcaag
    33541 atttgtgttg acagtcgcac cggaaaataa gacacgattc gaagaaatga tgggagatgc
    33601 tgctgtttta gcaggtaagg tgacggatga agcgataatc gaaatttcag caactgacgg
    33661 tcagatcaaa atagaaactg cagtagcaag aaagtgctgg gaggatgcaa tcgtatgtct
    33721 tatgaagtga agagtttaaa tgaagaatgc gggatcttcg gtgtttgggg tcatccagac
    33781 gccgctagtg tggcatactt cgggctccat agtcttcagc atcgaggaca agaaggtgca
    33841 ggtatcgtgt ccaatgatcg aggaaagctt aaggggcatc gagatttggg gctgctttct
    33901 gaggtattca aagatcaaag aaaattgcag cagttaacag gagaagctgc aatcggacat
    33961 gtacgttatg caacagcagg caatggaagt gtggacaata ttcagccttt tctattcaaa
    34021 tttcatgatc agtcgatcgg cttagcgcat aatggtaact tgatcaatgc tcgttccctt
    34081 agaaaagagt tagaggaaaa tggggcgatc ttccattcta actccgatac ggagatattg
    34141 atgcatttga tccgacgaag tgaagaaaca gattttttaa ataaattaaa aagtgctttg
    34201 aatgaagtca aaggtggctt tgcctattta ttaatgacag aaacggcaat gattgccgct
    34261 ttggacccaa atggttttcg tccattagca atcggacaaa tgaaaaacgg agcatacgtg
    34321 attgcctcgg aaacttgtgc attagaagtt attggggcac gttttataag agatgtccag
    34381 cctggtgaga tagtgatcat caatgacgaa ggaatccaga ttgattgctt tacgaaggac
    34441 acgcagcttt ctatttgttc gatggaatat atctattttg ccagaccaga ttcaaacatc
    34501 gcagggatca atgtgcatac tgcacggaaa aatatgggac ggaatttagc gaaagaatcg
    34561 ccagtaaaag cagatatggt cgttggcgta cctaattctt ctttgtcagc cgcaagcggt
    34621 tatgcggaag ctagtggaat cccttatgaa atcggattag taaaaaatca atacattgcc
    34681 cgaacattta tccagccaac gcctgagcta agagagcaag gtgttcgaat gaaattatct
    34741 gctgtacgag gagtagtgga aggtaaaaag gtgattatgg tcgatgattc aattgttcgg
    34801 ggtacgacaa gcagacggat cgtccatctt ttgaaagaag caggggcaaa agaagtccat
    34861 gtgaggattg cttctcctcc tttgaaatat ccatgttttt acgggattga tattcaaacg
    34921 cgtaaagaac tcattgcggc aaatcacacg attgatgaaa tcaaagaatg tatcggtgca
    34981 gattctttag gttttttaag tgaagagggt ctgatcgaat cgatcggtct ggaaaaagat
    35041 gctccgtatt caggattgtg tatggcttat ttcaacggag attatccgac gccgttatat
    35101 gactatgaag aaaaatatca ggaatcacta aaagaaaaag tatcgttctt ttaaaagcag
    35161 accaagaagg gagtatatga attcaatggc aaatgcatac gcaaaagctg gcgtagatgt
    35221 cgaagctgga tatgaagtag tagaacggat caagaagcat gtcaaaaaaa cggaacgttt
    35281 aggtatgatg ggcgctatag gaggattcgg cggttgtttt gatttatcgg tctttcaatt
    35341 aaaagagcca gtccttgtct cggggaccga tggcgtgggg acgaaattag cagtggcaat
    35401 cgaagcagac aaacacgata caatcgggat cgactgcgta gcgatgtgtg tcaatgatat
    35461 cttagcacaa ggcgcagagc cgttatattt cttagactac ttagcaacgg ggaaaaatga
    35521 tccgttacgt ttggaaaatg tagtaaaagg tgtagcagat ggatgtgttc aaggaaatat
    35581 ggcgctgatt ggcggagaaa cagctgaaat gcctggtatg tactcaggta atgattatga
    35641 tctagccgga tttgctgtag ggatagctga aaaatctcaa ttattgacag gagaaacgat
    35701 caacccagga gatgtgttgc ttggaatagc atctagcggg attcattcaa atgggtactc
    35761 tcttgttcgc aaaattttct ttgagcagca gcagttttct ttatcatcaa aactgccaga
    35821 attgaaaaaa acacttggcg aagaattgct tgagccaacg aaaatctatg tttcttcctt
    35881 gcttccgctg atcaaagaaa agaaaataaa aggagctgca catatcactg gtggagggtt
    35941 tgtagaaaat atcccgcgaa tgttaccaga atctatggct gcacaaatca aacttggctc
    36001 atggccgatt cttccaatat tcggctgttt acaaaaatat ggtgaaattc ctgagatgga
    36061 gatgtatgaa atcttcaata tgggcatcgg tatggtcctg gcagtcgaag aatcgaaagt
    36121 aaaagaaata gtacacgaaa ttgagcaagc tggcgaaaaa gtttatgaaa tcgggaaagt
    36181 gatcgccaaa gaaaaacatc gtgtggtgtt tataggagaa gaacgatgag aatcgctgtt
    36241 tttgcttctg gaaacggaag caactttcaa gcgctagccg attatctatc gaaaaaagga
    36301 ttggaatctt cgattgactg gttgttttgt gatcagcctg aagcatatgt tttgaaacgt
    36361 gcaactgcgt tgagtgtacc ggcagattgt ttttcaccta aagaatttga ttcaaaaaaa
    36421 gagtatgaag aagcaatttt gcataaattg aaagaaaaaa agatcgattt gatcgtatta
    36481 gctggatata tgcgaatcat tggaccggta ttgctgaaaa attatgataa aagaatcatc
    36541 aatatccatc cgtctctttt acctgccttc cctggtttgc atggcatacg tgatgccttt
    36601 gaagctggag taaaagaaac gggtgtcaca attcattata tcgaccaagg tgtagatact
    36661 ggaccaatca tccggcagga aaaagtgaga attgaacagg aggacacgtt cgattcttta
    36721 gaagaaaaaa tccatagagt agagcatcga atctatccag aagtgattag tgaaattatt
    36781 gaaaatggag gctatctgaa atgacaagag cattgatcag tgtatcagat aaaactggga
    36841 ttgtagcatt cgcccaaggt ttgattgaac aaggagtaga aatcatttca acaggaggaa
    36901 caaagcatgc gttggataaa gctgggatca aaacgctttc gatcgaagaa gtgacagggt
    36961 ttcctgaaat gatggatggc cgtgtcaaaa cacttcatcc taaaatccat ggtggtcttt
    37021 taggaagacg cgatctccct agccatatgg aggcaatgga aacggaaaat atccaaccaa
    37081 tcgactttgt ttgtgtcaat ttatatcctt tcaaagaaac gattatgaaa ccagatgtcg
    37141 aaatagcaga agctattgaa aacattgata tcggtggtcc tagtatgctc cgtagtgcag
    37201 caaaaaacca tgaatttgtc acctctgttg ttgatccatc tgactatgaa gaagtacttt
    37261 cagaattacg tcagtatggg catacttcac tttctttcag acaaaaacta gcggcaaaag
    37321 tctttcgtca tactgcggca tatgatgcac tgatcgctca atacttaacg gattgggtgg
    37381 aagaaaaaga accggaaaaa ttgacactta cgtatgaacg aaaacaaacg cttcgttacg
    37441 gtgaaaatag ccatcaagcc gctgcctttt atcagtccgc tcttctggaa aaatattcga
    37501 tcgcagcagc aaaacaactc catgggaaag aactttctta taataatatc cgagatgcag
    37561 atgctgcgct acggatcatg aaggaatatg acgagccaac ggtagtcgcc ttgaaacaca
    37621 tgaatccttg tggtattggg acagcatcta cgattttaga agcgtgggaa gcagcgtatg
    37681 aagcagatcc tgtttcaatc tttggtggga tcatcgtttt gaatcgagaa gtagatctgc
    37741 caacagcaga acagatgcat aagctgtttc tagaaatcat cattgcccct tcttatacac
    37801 aagaagcttt ggaattactg caaaaaaaga aaaacatccg attactgaca gtagactttg
    37861 cgcaggaaga aaatcaaaat cgagaagaaa cggtctcagt cttaggtgga cttcttgtac
    37921 aagatcaaga tctggcaata gaaaatgaag aagagtggaa agtcgtgaca aaacgtaagc
    37981 cgactccagc agaagcaaaa gcattagtgt ttgcttggag agctgtcaaa catgtgaaat
    38041 ctaatgcgat cgtactggca aacgaacgtc agacagtagg aatcggagcc gggcagatga
    38101 atcgagtcgg ttcagtaaaa attgcgattg aacaagcgca agagaaaatg gaaggtgcag
    38161 ttttagctag cgatgcttat tttccaatgg atgattcggt tgaatatgca gccaaacatg
    38221 gtataaaagc aatcattcag ccaggaggaa gcatcaaaga ccaagattct attgatatgg
    38281 cgaataaata cgatctagca atggtcttta ctgatgttcg gcattttaga cattagagag
    38341 gagtcggata aatgaacatt ttggtgatcg gtgcaggtgg tcgtgaacat gcaataagta
    38401 aaaaactttt agccagtccg aaggtggata cggtgtattg tgcgccagga aatccgggga
    38461 tgacaaaaga tggtatcaat tgtgtcgcta tcagtgagcg agatcattca gcgttaatcc
    38521 attttgttaa gaaagaggct attgattgga gtatcgttgg tcctgaagtt cctttgttaa
    38581 atgggatcgt cgatgatttt atggcggaag gattgaaaat cttcggtccg acaaaagcag
    38641 cagctctgat cgaaggttcg aaaagttttg ctaaacaatt aatggatact tatcaaatcc
    38701 cgacagctaa atccagaagt tttgaatgtt acgaaaaagc agcagcgtat atcaaagaaa
    38761 atggtgcgcc aatcgtagtg aaagcggacg gcttagcagc tgggaaaggt gtagtcgtgg
    38821 ctaccacagt gaaggaagcg ctggatgcgg cagaacaaat gttgaaccag catcgatttg
    38881 gggatagtag caaaaaaatc gtcgtagaag agtttttggc aggagaagaa ttctcccttt
    38941 tggcgtttgt ccgtaatacc aaggtgtatc cgatggtcat ttcgcaagat cataagcggg
    39001 catttgataa cgataaaggg ccaaatacag gcggaatggg tgcttattca ccagtaccgc
    39061 aaatttcaaa aaagatgatt gaaaaagctg tggaagaagt tttaaaacca gcggctttgg
    39121 gaatgaaaga actaggacgc tctttcacgg gtgttttata tgcgggtttg attgctacga
    39181 aggaaggacc aaaagtgatc gaattcaatg cgcgtttcgg tgatcctgaa acgcaagtcg
    39241 ttctttctcg gttgaagagt gactttgcgc aagtaatcga tgatttatta gagaatcgta
    39301 cagtagagtt aaagtggcag caagaaggat acaatgtagg cgttgtggtt gcagctgccg
    39361 gttaccccga agaatatgag acaggaatgg ttctaccaga ttttctggaa gaagagcttt
    39421 ctgtttacta tgctggagtt tcctcaaata acggcaaact agttggagca ggaggacgtc
    39481 tttatttagt agaagcatac ggtgagacga tcaaagaagc acagaaaaaa atttacaccg
    39541 cgttaatgga taaaacgaca gatggaacat tttatcgtac agatattgga gaaaaagctg
    39601 ccaatagcga actgatcgtg aagtaaatca gctgcttcca tttataaaaa atacaacaaa
    39661 cataatcgga agcgccgatt ttagtgaagc cttttcataa agagtgtggt acacttttgt
    39721 tgtgtatata aataaggagg agttcagatg aaaaaaattc aattaggtac ttctgatcag
    39781 aaagcagctg cagtgatctt aggctgtatg cgtatcaaca atgcggaaga tccagtaaaa
    39841 gtgattgaga cagcttatga aaacggcatt gatttttttg accatgcaga tatttatgga
    39901 aacggtgaat gtgaagaaat ctttgcagat gctctagcaa aaacatcaat caaacgagaa
    39961 gatcttttta ttcaaacaaa atgtggaatc gttccaggtg tgatgtttga tttttctaaa
    40021 aaacatatca ttgaatctgt agaaaaaagt ttgacccgtc tgaaaatgga ttatgtggat
    40081 gctttacttc ttcatcgtcc agatacattg gtagaaccag aggaagtagc tgaagcgttt
    40141 gatgaattgg aacggtcagg aaaagttcgt tattttggcg tcagcaatca aaaaccaatg
    40201 caaatcgaat tgctgaaaaa atatgttcgt caaccattag tagctaatca gctgcaattt
    40261 ggcttgaaac atactggaat gatcgatcaa gggattcatg tcaatatgac agatgaagca
    40321 agtatcgatc atgacggtag tgtacttgat tattcccgat tgcatgatat gacgatccaa
    40381 gcatggtcac cataccagta tggatttttt gaaggtgtat ttatcgggaa cgaaaaattc
    40441 cctgaattaa accaaacatt agaagaacta gcagctaaat atcaaacgac accaactggc
    40501 ttggcttctg cttggatttt acgccatcca gccaatatgc aagtgatcgc cggtacgatg
    40561 aacgtagggc gaatcaagga aatcgctcaa gcttcagaaa ttaatatgtc tcgggaagat
    40621 tggtacgaat tgtaccgtgc tgctggaaac attttacctt aaagattgtc ataagcaggt
    40681 caaaagggct ataaattaaa aagacagaat aacttgaaag ctgttttcag cttcgagata
    40741 ttctgtcttt ttttattgca aatggaaaga gtatcattgt acggatttcg tttattagtt
    40801 atttttgttt ttaaggaaaa gctgtgtccg atattctttt ggagaaatcc cttgtttttt
    40861 cttaaataaa taactgaaat agttagggtc attataacca atttcaaaag caatatctga
    40921 aatacgatag tctgattgct gcaataattt ttttgctaat tcgattcttt gttctgtcag
    40981 ataatcgatg aatgtttggt taaacgattg agaaaaaatc gtactgaaat gagagggact
    41041 taatgcaact tgttgagcga cccaagttaa ggacatatct ggatcggtaa aattttcttt
    41101 gataaaatcc aatgcatggt tcaaaattgg ctgatatttg ttccttgaag gctgtgaggg
    41161 cagagcagtt aagaaagaaa tgaacatata aactgtcgaa cggtaaagcg agtcgtcggc
    41221 gctgattgct aagcgttgac tggtggatgt gcaatgaacc atttcttgcg ggattttctt
    41281 ttctttcagg cagacatgct ggagtagctt agtcaagaca aataaacgat ataatcgtgt
    41341 tcgagttggt gtgccttgtg gtttcgtcaa gtgttcgatg tacttagata cttcgttttt
    41401 cgataatgaa gacaaatcaa gtgagaggtc aaagtaaaag acagaatcaa ctggaagttt
    41461 cgcttcttga atcaaatcct catagctgat aatttgttct ttaagggaac tggcggtttc
    41521 aagtatcatc tgcgtgatct caaaagatgc aggtaattcg ctgattcttt ctgcgacagg
    41581 accaatggcg acagaaaaat tatttttttg tcccttttct aattcatgga ccaacgtttg
    41641 ggctacctga taactggtct cgatcacatt ttcttcaaga gaatcaacta ttaaaaattt
    41701 gatgaatcga gaggaaacag cagagaagat cacttgttga ttctccctaa ataaaaactt
    41761 caaataatca ctgagatgag cgtaatcttc aaagtctgta ctgacttggt ttgctgctaa
    41821 taatacggtc atttttttcc ctgctaaaga gcgattgaaa gattcagcaa gtttcaatgt
    41881 ttcactgatc gtaagtgagc ctttgaacaa accgttcaag aaatgatttt ttttcaattc
    41941 gaaaacaaga tcagaagaag tgtgcgtttc tttttgctgc aaatctaaag cagttactgc
    42001 tttttctatt gcttgtttca attcgctact tttaatcggt ttaagcagat aatcatctgc
    42061 ctgtacctgg attgctcctt tcatataatc gaaatcgtcg aatccactaa taaatatgag
    42121 acgagtccaa ggaagtagtt tccttgcttc ttttgaaaaa gtcaacccgt ccatgaaagg
    42181 catttggata tcagtcagaa tgatgtcggg ctgtaagtcg ataattgaag acagtgccat
    42241 ctcaccatct ccagcttcgc cgacataagt gattggataa taagaaccaa ggacagttat
    42301 ttgttcccgc aagttattgc gaatgaggta ttcgtcttcg atgataaaaa ctttatacat
    42361 gtttgtttcc tccaattgtt ttgggagata gagggatcat cagtgtgaca gttgttcctt
    42421 ctcggtattt gctgtcaatc gtgataggtt tttgatcatt tccgtaataa agaaggagac
    42481 gcttgtttac gttgtaaagt ccgtagccga tactgaaatc tgaatcgatc cctttggcta
    42541 actctttacg tatttctgcc agtttttctg cagggatgcc aatcccgttg tctataactt
    42601 tgaattggat catctcatca attttgcatg tggtaatacg aataaatcct ttgtgacgga
    42661 cgtacttcgt tccatggtat acagcatttt caatcaatgg ctgcaagatc atttttaaaa
    42721 tagaaacagg aaaaagtgtt tctggtatat cgatcttata gtcaagcata tggccgtatc
    42781 ttatttttaa gatgactaga taatcattga tatggctaat ttctttttca agaggaatcc
    42841 agtcttgtcc tttgcttaaa gacgtacgaa aaaagccgga aagtgcatgg gtcatagtca
    42901 gagcttcttc aaagcagtct tgttcgatca aagaaataat ggcatccaaa ctgttataaa
    42961 taaaatgggg agtaatctga gcttgcaata cacgaacttc actttgtgct aaatggtatt
    43021 gtttcaaagc gttctcccgt aaagactggt ttagatcttc cgccatttta ttcatgctag
    43081 cggtaagtgt ttgtaattcc agtgtttccg gcagggttaa acgaaagcca aggttccctg
    43141 aagaaagttg ttctgacatc tcgatcagct gattgatcgg ttcttggacc tttctctcta
    43201 aaaagcgacg attctttttc gcatagaaaa aaatggtact aagaactcca agttccacta
    43261 ttgttaatag aatgagcgag cggacaagtg tcgtattttt tttgcttgct aagtcgatct
    43321 ccacacgaac aaaatcttgt aagatatctg acagcagttg agtgacagaa tctacctgat
    43381 tgatgatctc ttcattggta tccataaaat cttttgccaa gatattattg atcagctcgt
    43441 tttgataatc ttccagtgta tcgatcgtac gtagcgatac atctaacgta ctaatttctt
    43501 taagtgtatt tgtattattt ttgatctctc gaatatcatt cctaagttct tctaggatat
    43561 tttcctcatt gaactcatct acggttactt ggccagaaat caagtcccac atactttcca
    43621 aaactttttg atcaaccttc aaagcaattg catctgcttt ttggatattt gcgatcgtct
    43681 gttgataaat caaaagctgt tgcgaatata acagtatgct cagtagcaaa gggataacag
    43741 caaatagaag catggctttg tttgcttggg caaaaatctg ttttatgctt aaattttttg
    43801 tcatgatact tctccagtca ataatttctg gttgggatgt tagctatatt ctgctgggaa
    43861 aagacagtct cggaaataaa aatatcttta ggtaatgttt ttcctgtttg aatatttcca
    43921 aaataacgag taacggtatt ggctacatac cagccgacat caggtttaca ctcgactaca
    43981 caattgacga ttcctgagcg tagcttctcg atcatatctt cttgtccatc aatagttaca
    44041 atgatcaaat cttctccagg tttgattgat gtttctttta tcgcagctaa agcaccgtga
    44101 gtcatttcat cactatggct gtataataca tcgatttcgg ataaatcatt tgtttctaaa
    44161 tatcgtttca tctggtcttt tcctttcatc cgaataaaat caccgacaat tcggtgaaca
    44221 atagtcatcg gaggtttatg gtcgatggtt ccatcttttt ttagggttgg tttacgattg
    44281 attgattcca aaaatccttc ggagcgtagc ttggtcggtg tggagttctc tgaaccagca
    44341 agttctagga ttctgatttc ctgtttcttt gaatttgtga agtgattgct gacaaataaa
    44401 cccgcccgat ttccttctgc tttgaaactg gggccaatgt gggtgacgaa aagctcggga
    44461 tcattcgttt gaatatgtct gtcgacaagt atgacaggga tccctgctcg ctttgcttct
    44521 tttaatacag agtcccaccc ggattcttgc aaaggagtaa aaatgatcat atccacttta
    44581 taggcaatga acgtccgtat atcttggatt tgccgttcct gattcatgta gccatttcgg
    44641 tagagaactt ggtaatcttc tttttcaagc gcagtgataa ttgattcagt atgctttttc
    44701 cgccagctac tctccgttcc tgattgcgaa aaaccaacga ctagtgggtc aggtgcttcc
    44761 tttgtattag gtgtacaccc catcatttgg taagcgatta caacaagggc taaaaaaaat
    44821 aaaacacgtt tcactttaaa tcactccatc tggatttgtt agtactatct tatcagataa
    44881 aagggaaaat caaagtcaaa aggaatcaat cgaaaaaaat ccaagaaact taaaaaaatc
    44941 caagacaaaa aaagtacacc taaaaaattt aaagtaaatc ccataaaaaa atcaatgtta
    45001 acgctttctt tattagctat actcggtgta tcaattgaaa tgggggataa aaaatgaaaa
    45061 acaaatttag aaagattgtt gggactatcg ctattttgac cgcaagcatt ctattaagtg
    45121 cgtgtggcaa ttcaggatct gcagatgata gtacggggta tgtaggaatc gctatgccga
    45181 ccaaatcagc agaaagatgg atcgctgatg ggaacaacat ggtctcggaa ttagaaaaac
    45241 tgggttataa aacagatctt caatatggag aagataaagt agaaaatcaa gtagcacaaa
    45301 tagaaaatat gattacaaaa ggggtagata cacttgtgat tgcttctatc gatggttcgg
    45361 ctttaactga tgtgttagct aaagcaaaag aagcagatat caaggtgatc gcctatgatc
    45421 gtttactgat gaattcagaa aatgtcgatt attacgcgac ttttgataat tttggagtag
    45481 gtgtatcgca agcagcttat attgaagagc acttaggatt gaaagaagga aaaggaccat
    45541 tcacgattga attatttggt ggctcgcctg acgacaacaa cgcactaatc aattacaacg
    45601 gagtgatgtc tgttttacaa ccatatatgg acaacggtca gttggtcgtg ccatctggac
    45661 agacgagttt cagtcaaatc gctacgcttc gctgggatgg ttctacggcg caagcaagga
    45721 tggataatct gttaagcgca aattatactg accaaacatt ggatgctgtt ttgtcgccat
    45781 atgatccaat aagtttagga atcatttcgt cattaaaagg cgtggggtat gggagtgaaa
    45841 gtaaaccttt acctgtgatt actggacaag atgcgacagt tgctggcgtt aaatcgatca
    45901 ttgccgggga acaaacacaa acgatcttta aagacacacg tatcttagca aaaaatacga
    45961 ttgaaatgat caaagcaatc agtgatggag aagaggttcc ggtcaatgat actgaaactt
    46021 atgataatgg ggtgaaaact gtccctacgt atttagcaaa tacagtatct gtcgataaag
    46081 ataattatca agcagagctg atcgacaccg attattataa agaatccgat ctgaaaaatt
    46141 aagaggaacc aaacaaggaa ctaaagagat ctaagtcaga gagaggataa gaattatggc
    46201 ggattgtatt ttaaaaatgg cagatatcac caaaaaattt tctggaatcc gagcgttaga
    46261 ttgcgtgaat ctgatgattg aacgtgggga aatccatgca ttgtgcggag aaaacggagc
    46321 gggaaaatca acattgatga atgtcttgag cggcttgtat ccatatggct cctatgacgg
    46381 ggaaatcttt tatgatggaa agctgtgtca atttaaagat ttgaaagata gtgaagaaaa
    46441 aggcatcgtc atcattcatc aagaattagc actaagtcct tatctttcaa taaaagagaa
    46501 tatttttctc ggaaatgaac aagcagaaag aggcgtgatt gattgggaac tgacagaaaa
    46561 gaaaacatat gaactgctga ataaagtcgg tttgtctatc gacccgaatc ttctagtatc
    46621 ccagattggc gtagggcaac agcaactagt tgaaatagct aaagcattat caaaatccgt
    46681 ccgtctgttg attttggatg agcctaccgc tgcattgaat gaagaagaaa gcgcgaattt
    46741 gctgagattg atccgagagt tgaaagagca aggtgtaacc tccatcatta tttcacataa
    46801 gctgaatgaa atcgtggata tcgcagatcg aatcaccatt ttacgggatg gacagacgat
    46861 tgagacacta gaaaatgaaa tgatcagcga agagcatatt attcgcggaa tggtgggcag
    46921 agatttagtt gatcgttatc ctgaaagaaa accggatatt ggagaagttt attttaaagt
    46981 agaagactgg acggtctatc accctcttga tcacgagcga atcataaacg accacatcaa
    47041 cttgcatttg aaaaaaggag agattgtagg aatagctgga ctgatgggag cgggcagaac
    47101 tgaattcgct atgagtctat ttggacattc ttatggaagc aagatatccg gacgtatatt
    47161 aaaggaaggg gcagagatat cagttaagac cgttccttca gccattgcaa acggactcgc
    47221 ttatgtctcg gaggaccgaa aatctttagg actgaatctg ctgatggata ttcgggaaaa
    47281 cgtgacgctg agcagtttgg ataaaataag tcaaaaagga gtattagata aagaaaaaga
    47341 agtaactgag gcagaaaatt tccggaaaaa gatgcgtata aaaacaaact ccatccatca
    47401 aattgtcagt agtcttagtg gtgggaatca acaaaaagtc gttttatcca agtggctgat
    47461 gacacaaccc gatattcttt ttttggatga gccaacccgt gggatagatg ttggggcaaa
    47521 atatgagatc tacacgatta tcgaagaaat ggcagcaaat ggcaaagctg tctgtcttat
    47581 ctcttctgaa cttcctgaaa tattagggat gtgtgatcga atctatacga tgaacgaagg
    47641 acgtattaca ggagaagtct cgcgagaaga tgcagatcag gaagtcttga tgaaattaat
    47701 gacgaaagaa gaggtgggtt aagttggaac aggcaaaaaa tcttacggat aaaaaagaga
    47761 aaaaactaaa tttgaaaagt agagcagctg atctttttgg tcgctacagc atggtgatca
    47821 ttttagcggg actacttatt gcgtttcaat tgatgacgga tggtattttc tggcgtccat
    47881 tgaatataac taaccttgtt ctgcaaaata gccatatatt agtactagct gcagggatgt
    47941 tattagttgt gctcttaggt catgtggatt tgtcggtagg gtcagtgatg gcgtttgttg
    48001 gtgcaattgc gggcatgatg atggtcaatc gccaaatgaa cccgtggatg acagttatcg
    48061 catgtcttgc agtaggcggg ctgatcggcg catggcaagg tttttgggta gcttatgcag
    48121 ggataccggc gtttatcgtg actttagcag gattgctgat gtttcgtgga ctgacacaag
    48181 ttgttctagg aggccaatct ctagcacctt ttccagctgt tttccaaaaa atgtctacgg
    48241 gttatttacc agacttaagc gaaggaagca gccttcactt cttgacattg attttaggaa
    48301 tgatcatcac gatcgtgtta gttgttggtc aatggcgaac aagaaatcgt cggaaaaatc
    48361 atttatttga agtggaatct ccaacagctt tcttggtaaa ggcggtattt acagcagtcg
    48421 ttgtactagg aataacttat atctttgcct cttatcaagg gtatccgatt attttgatca
    48481 ttcttggttt gatcgttgca gcatatgggt ttttgacaaa taaaacagta gcaggtcgac
    48541 agatttatgc gacgggcgga aatcgaaaag cggctgaact atcagggatc aaaacaaagc
    48601 gaatcacgtt ctgggtattc gtcaacatgg gagtcatggc agctttagct ggattagttt
    48661 tagctgctcg attgaatgcg gcaacacctc aagcaggtac atcgatggaa ctggatgcaa
    48721 tggcggcagt atattttggt ggtgcttcga cttccggcgg cattggaaca atcatgggtg
    48781 cgattgtcgg tggcttggtc atgggtgtat tgaacaatgg catgtcgatt ttaggcgtcg
    48841 gggtagactg gcagcaggca atcaaaggat tgatcttgct tttagccgtt gtgctagact
    48901 tgtataataa gaaaaaacga acaacgtagg agaacgccgg ttattcagaa aaaagactgt
    48961 gacaagacat ttgtcacagt ctttttttcg ctaaaagcga acattcattg tttcgtttgt
    49021 atagactaaa aataatatat gtttttttac cattcgtata aattctcttt ttgctcttga
    49081 tttttttgct taattgagtt aaattacata gggcgctaaa aaaagccttg attaaattaa
    49141 taatgttcgt gttttgctgg atgtgaacat caggaggata atgtaatgaa agtatttgat
    49201 tacgaagata ttcaattaat tcctaataaa tgtatcgtaa atagccgttc tgaatgtgat
    49261 acaacggtca cattaggtaa acatacattc aaaatgccag tagtgcctgc caacatgcag
    49321 acgattattg atgaaacaat cgcagaattc ttagcggaaa atggttattt ctatatcatg
    49381 catcggtttg atgaagcagc tcgaattccg tttatcaaaa aaatgaaaaa gcgtggattg
    49441 attacctcga tcagtgttgg cgtcaagaaa gaggaatatt cctttataga gaagttggca
    49501 gaagaatcgc taaatcctga ttatatcact atcgacatcg cgcatggaca tgctaactca
    49561 gttattgata tgattcagca tattaaaaaa tatttgcctg aaacttttgt gattgccggt
    49621 aatgttggta caccggaagc cgtccgtgaa ttggaaaatg cgggcgcaga tgcaacaaaa
    49681 gtcgggattg gtccaggaaa agtatgtatt acaaaaatca agacaggctt tgggactgga
    49741 ggctggcaac tggcagctct tagatggtgt gcgaaagcag ctcgcaagcc gatcatcgct
    49801 gacggtggga tcagaacaca tggcgatatt gcaaaatctg tccgttttgg tgcgacaatg
    49861 gtcatgattg gttcattgtt tgccggtcac gaggaatctc ctggcgaaac aaaagtcgaa
    49921 aatggaatcg tgtataaaga atactttggt tctgcttcag aattccaaaa aggcgaaaaa
    49981 cgaaatgttg aaggaaagaa aatctggatc caacacaaag gatctttgaa agatacacta
    50041 gtggaaatgc aacaagacct tcaatcatct atttcttatg ctggaggaag agatctggaa
    50101 gccattcgaa aagttgacta tgtcatcgtg aaaaattcga tttttaatgg agacacaatc
    50161 taaaaaataa ataaaatatt aggatgttgt gaaaaagttg tcctgcatta agtaataaga
    50221 acagccaaac aaaaatagtt ctttatatgt tttgtttggc tggaattatt atcgcagata
    50281 caagcttttg aacatcatta ttcagaataa gggactgtga taagattttt gtcacagtcc
    50341 cttatgtttt gcaaaaaaag tttttctttt ttctcgtaaa ttcggtaaaa tcaaaagaaa
    50401 aaatagacaa tagaaaagag aagcttatgt gggaaaaagt agagaaaaaa caaggaccga
    50461 tttatcgtca aattatggaa cagattatga gagaaatcga aaacggaagg atcaatcctg
    50521 gaagtcaact tgaatcagaa cgaaaactag ggcaactttt tggtgtgaat cgttccaccg
    50581 ttgtccatgc attggaagag cttagggagc ttggggtact aacgagcaaa cgtggcagcg
    50641 gatggtttgt taatcagact gaatggggga aattcgctgt tccaagaatc gattggcggc
    50701 aaatgatctc tcctcgttat gagcagacgg actggtatga gcaaaaaata agagaagcaa
    50761 agcagatcca aaaaacatcg tttcttgatt tatacgctag cgagatgcca gatgagcttt
    50821 tgccgaattt tgagtttcct tcttattctc ttgaagaaat cttagcggaa gaaaaagaaa
    50881 tggatctttt aggctatact ccgttacgta acaaaatcaa acggtatttg gaaagtaaat
    50941 ttgaattggc attttccccc aaccagcttc ttgtgactgg tggcggtcag caagcaatct
    51001 ttttgatttt acaaacgatt ctttcagctg gagaggggat agctgtagag tcaccttctt
    51061 ttttttaccg attacctctt ttcaaagctt caggaacgcg tttatttggg ataccgatgg
    51121 atgaagaagg gatcgactta gaaaaactga aagaatcgat ccataaaaat aaattgaaag
    51181 cagtgcttat caacccgaat tttcaaaacc ctacaggaaa agtgatgagt caaaaacgac
    51241 gagaaaagct agtagaattg tgtcgacagt atcggcttcc aattattgaa gacgatgtat
    51301 ttacggatct ttcatttcta aaccaagaag aagtccttcc tatacgaacg attgatccgg
    51361 ataatgtgtt atacgtcggt tcgttatcta gggttttagg aaaaacaacg aaaatcggtt
    51421 gggtgatagg acctgagact tttatctcgc aactagctca agcgcaagaa atgatggagt
    51481 tttcgatgaa tatccttaca caaatcacag tggctaatgt atttaatgaa gcaattgatt
    51541 tgaaaatgca agatgtaaga aaaaagttga aagaaaaaag ccgactgata agcgcttggg
    51601 gagattcaca atcgtttttc aagcttcatt caattttagg tggttactat gcctggatta
    51661 cttgggatgg gaaaaaacta gaccccgaac tagcagaaaa agtagtagat atgggtcttg
    51721 gaattgcacc aagtctactt tttgggcaag atataaatgg aatcagaatc aattacagta
    51781 ggctggatga aaaccaaata ccgttgtttt attcaaagat gaaaattcta gaaaagtggt
    51841 taacagaata atttcacaaa gtaaatagat taaagaatat aacagcttgg atttaaattt
    51901 caagctgttt cttttttttc ggaaaaagaa tacgatataa agaaactaag aaaaaaccat
    51961 tatttgtacg tccgttcacg atgtgtaaat aaaataaatg tttgcaacaa aactgtataa
    52021 caccaacgtt tttaaataga aacagatggt tgtaagtttg attagaaaat agaaaaaatg
    52081 cagatgaaat ataaaacgct ttccttattg tgattttatt cactaatgct gttaatatgc
    52141 ggattggcat aatttccttt catcgtgaaa atttgtgctt ttagcttgta tttctcataa
    52201 atccatgata atttattaat gaagacggtt aaatagtgat acagttttat tcactgtttc
    52261 aatcgcagaa tgaagagatt ttcttataga tgagagagga atgtgtgaca aatggcaaac
    52321 aaaaaagcac cgatcgactt ccaagcactg ctagatgaag tcaatgcaga tttcccagta
    52381 tatcaagcac ttgatcaaga tggaaacgta gttaacaaag atttagtacc tgatttatcc
    52441 gatgatgaac tcgttgaatt aatgactcat atggtatggt ctcgtgtatt agaccaacgt
    52501 tcaacagcgc tgaaccgcca aggacgccta ggcttttttg caccaactgc tggacaagag
    52561 gcaagtcagc tggctagtgc ttacgcattt gataaagaag atgttcttct tccaggttat
    52621 cgggatgtac ctcaactagt aaaacatggt ttacctttat ctcaagcttt tttatggtct
    52681 cgaggacatg ctgcaggtaa ttcttatccg gaagaattga aagctctacc accacaaatt
    52741 atcatcggtg cacaatatgt acaagcagcc ggtgttgcat taggtttgaa gaaacgaaac
    52801 aagaaaaatg tcgtcttcac ttatactggt gatggcggtt catcacaagg tgatttttac
    52861 gaagcaatca atttcgctgg cgcttaccat gcaaatgccg tattttatat ccaaaacaac
    52921 gggtatgcga tctctacacc tcgtgaaaaa caaactgcag caaaaacact tgcacaaaaa
    52981 gctgtcgcag ctgggattcc tggtattcaa gtcgatggaa tggatccgct tgcagtatat
    53041 actgtatcta aaatggcacg ggaatgggcg atcagtggaa atggaccagt cctaatcgaa
    53101 acactgactt atcgttatgg accacataca ctatctggtg acgatccaac ccgctaccgt
    53161 acaaaagaca cagatgacga ttggcagaaa aaagatccat tgatccgctt ccgtaaatat
    53221 ttgacggaaa aaggactttg gtctgaagaa aaagaagaac aagtcatcga agcaactaaa
    53281 gaagaaatca aagcagctat tgctgaagcc gacaaagtac caaaacaaaa ggtttcagat
    53341 ttcttgaaaa acatgttcga agtatctcca caatcaatca aagaacaaat tgcaatttat
    53401 gaagcgaagg agtcgaaata atcatggcac aaaaaacaat gatccaagca atcacagatg
    53461 ccttagcact tgaactagaa aatgacgaga atgtcgttgt ttttggtgaa gatgttggga
    53521 aaaacggagg agttttccgg gcaactgaag gattgcagga aaagttcgga gaagaccgag
    53581 tattcgatac tcctttagct gaatctggaa tcgcaggatt gagtttcggt cttgcgttag
    53641 aaggatttcg tccagttcct gaaatccaat tctttggttt tattttcgaa gcaatggacg
    53701 aagtagtagc tcaaatggct cgtacaagat atcgaatgag cggcactaga aatctaccca
    53761 tcacaattcg ttcgccattt ggtggcggtg ttcatacacc agaattgcat tcggataatt
    53821 tagaaggttt gatcgctcag tctcctggta ttcgagtagt gattccttcc aacccttatg
    53881 atgcaaaagg actattgatt tcttctatta gaagtaacga tccggttgtt ttcctagaac
    53941 acatgaaact atatcgctca ttccgagaag aagtgccgga tgaagcttac gaagttcctt
    54001 tggataaagc agcagttact cgtgagggaa cagatgtatc tattatcaca tacggagcaa
    54061 tggtgcgtga agcaatcaaa gcagcagaca atcttgcaaa agaaaatata tctgttgaaa
    54121 tcattgatct tcgtacagtt gcgccattag atgtagaaac gatcattcaa tccgtggaaa
    54181 aaactggtcg cgtagttgtt gtccaagaag cacaacgaca agcgggcgtt gccgcgcaag
    54241 tagtttctga gatctcagaa cgcgctatcc tttcattaga agccccaatc ggacgagttt
    54301 ctgcacctga tacagtcttc ccatttggac aagcagaaaa tgtctggttg ccaaatgcaa
    54361 aagatatcga agacaaagta aaagaaatcg cggaatttta agaaaagaag ggacgaaaca
    54421 aagtcatggc ttatcaattt aaattgccgg atatcggtga aggaatcgca gaaggtgaaa
    54481 tcgtcaaatg gttcgtcaaa ccaggagata cgatcaatga agatgataca ttactagaag
    54541 ttcaaaatga caaatcagta gaagaaatcc cgtcacctgt tacaggaacg gttaaaaatg
    54601 tgattgttcc agaaggtacc gtagcaaatg ttggggatgt attagtagaa atcgatgcac
    54661 caggacacga agacaatgaa ggggacagtg gtgtagccgc agaatcccaa actccagcta
    54721 aaccggctgc tgaacccact gttgatacag aatcagctgg atcgtcaagc gaaggagtct
    54781 tccaatttaa gttaccggat atcggtgaag gaatcgcaga aggtgaaatc gtcaaatggt
    54841 tcgtcaaacc aggagatacg atcaatgaag atgatacatt actagaagtt caaaatgaca
    54901 aatcagtaga agaaattccg tcacctgtca cagggacagt taaaaacgtg attgttccag
    54961 aaggcactgt agcaaatgtt ggggatgtat tagtagaaat cgatgctcct ggacacaata
    55021 gtgcaccgtc aactagtgcg ccatcagctg aagcaccaaa agaaaaagtg gaaacatcag
    55081 gttcagcaag tgtcgttgaa gctgccgatc caaataaacg tgtattggct atgccatctg
    55141 ttcgtcaatt tgcccgtgaa aaagatgtag atatctcaca agtaactgca actggaaaag
    55201 gtggcagagt aacaaaagag gacatcgaaa acttcttggc aggtggtcca agcagtgcac
    55261 cagcgaaatc agaagcgcca gaagcggcag caccgaaaga agcagctcct gcagcagaaa
    55321 gcaaaccagc tgcaccagca aaaccattca agtccaactt aggagacttg gaagaacgtg
    55381 tagcaatgac gccaacacgt aaagctatcg ctaaagcaat ggtcaacagt aagcatacag
    55441 ctccacacgt gacattgcat gatgaagtag aagtgtctaa actatgggat aatcggaaac
    55501 gatttaaaga agttgctgct gcaaatggta cgaaacttac tttcttgcca tatgtcgtga
    55561 aagctttaac agcgactgtt aagaaatacc cagtattgaa tgcatctatc gacgatgcaa
    55621 accaagaaat cgtttataaa cattactaca atatcggtat tgcaactgat acggatcacg
    55681 gactatatgt accaaatgtg aaagatgcag accgcaaagg aatgtttgct attgcagacg
    55741 aaatcaatga gaaagcaaaa ttagctcatg acggcaaact atctgcagaa gatatgcgca
    55801 atggaacaat tacgatcagc aatatcggat ctgtaggtgg cggttggttt acaccagtca
    55861 tcaactatcc agaagtagct attttaggtg taggaacgat tgcacaacaa ccaatcgtaa
    55921 atgctgaagg cgaaatcgtt gtcggtcgtg tgatgaaact gtcattaagt ttcgatcacc
    55981 gtatcgtaga tggagcaact gcgcaacaag caatgaataa tatcaaacgt cttttagctg
    56041 atccagagct attaatgatg gaaggatgat aaacaaatgg tagttggaga ttttgctgta
    56101 gaattagata cagttgtaat tggtgcggga cctggtggct atgtagctgc catccgcgct
    56161 gctgaaatgg gacaaaaagt agcaatcatt gaaagagagt atattggcgg tgtttgtttg
    56221 aatgtcggct gtattccttc aaaagcactg atagctgcag gacaccatta tcaagagtca
    56281 ctagattctg aaatgtttgg agtaactagt gaaaacgtca aactagattt tgcaaaaaca
    56341 caagaatgga aagaaaacaa agttgtccat acgttgactt ctggtgttgg tttcctatta
    56401 aaaaaacata aggttgaaac aatcgaagga gaagcgttct tcgtagatga tcacacacta
    56461 cgcgtcattc atccagattc agctcaaact tattcgttca ataacgcaat catcgcaaca
    56521 ggttcccgtc caatcgagat tccaggattt aaattcggag gacgtgtgtt agattctact
    56581 ggcggattag cattgaaaga agtacctaag aaatttgtga tcatcggtgg cggtgtgatt
    56641 ggtgccgaat tgggcggagc gtacgcaaac ttaggagcag aagtaacgat tcttgaaggc
    56701 tcaccacaaa ttttaccaac ttacgaaaaa gatctagtaa aattagtaga agatgatttc
    56761 aagaaaaaag gcgtaacagt cgtaacgaat gcaatggcga aagaagcagt cgataacggt
    56821 gacagcgtga cagtgaaata tgcagtggac gggaaagaag aatccgttac tgctgattat
    56881 gtgatggtca ctgtaggtcg tcgtccgaat acagatgata tgggcttaga acaagcgggt
    56941 gtcgaagtag gagaacgagg attgatcacg gtggataaac aaggacgtac gaacgtacct
    57001 aacatctatg ccatcggtga tatcgttcca ggggcggcat tagcacacaa agccagttat
    57061 gaagcaaaaa tcgctgctga agcaatctct ggcaaaaaag tagctgtaga ttataaagca
    57121 atgccggcag tagccttcac tgatcctgaa ttggcttctg taggtatgac gatcaaagaa
    57181 gcaaaagatg ctggtatcga agcaaaagca tataaattcc cattttcagg gaacggtcgg
    57241 gcattatcgc ttggtaaaac agaaggattc atccgtctag ttacgacgat cgaagataac
    57301 gtgcttattg gcgcgcaaat cggtggagtc ggcgcaagtg atatggtctc tgaattagct
    57361 ttagcaatcg aatcaggaat gaatgctgaa gatatcgcct tgacgattca tcctcatcca
    57421 tctcttggcg aaatcgtcat ggatgcttcg gaattagcat taggtttacc aatccatatt
    57481 tgatttgaat aatacaggcg aaacgcaact gaaaaatcag ttgcgttttg ttttttagaa
    57541 ttatcaataa tattattatg taaacttaaa aatatgacaa cttcttggtt tattaccact
    57601 tcctatgcta cactgaagag gaatatgaaa taggagagtt gaagatgcaa gaatatcagt
    57661 atccacttga tttagattgg acaacagacg aaatggtcat tgtaatgaag atgtgggaag
    57721 atctggaacg tgcgaatgaa aaagggataa acaatgaagc ttttttgaag acttatcagc
    57781 agtttaaaac tgttgtcaaa tccattggtg aggaaaaacg attgggacgg gaatttgaaa
    57841 aagcttccgg ttattcttta tatcgtacag tgcagcaagc aaaaaaaaat ccaaacaaaa
    57901 ctttgagaat gaacgggtga gataaatgga acagatgatt gatcatatca agtcctggct
    57961 tgaagaagct ggtgagaaaa tcaaatcttc tcaacaaaca ttaacaatct cgcaaaaatc
    58021 aaatcgaacg gatctagtaa caaatgtcga tcgaaacatc cagaattttc taatcgaaaa
    58081 aatccattcc tttgatccag aggcgaaaat attggcagaa gaagaagggt gtaatcaatt
    58141 atcggatctc gatggaagag tctttatcat cgatcctatt gatggcacct tgaattttgt
    58201 gattgaaggg gaaaattttt gtattatgct cgctgtttat gaatccggcg ttggaaagct
    58261 tggtttcatt tatgacgtga tgagaaatga acttttttgg ggtggaaaag gaataggcgt
    58321 gtataaaaat gatgagccat tgcctagacc agcaaataaa tccttatcgg aaggcttact
    58381 tggtgtgaat agttatcttt tcggtcataa taaatatgga atccgagaaa ttgcggaaag
    58441 cagcatgggg acacgtatgt acggatgcgc tggtcttgaa ctagtggcaa tcttgaaagg
    58501 aaaccacatt gcttatattt caaaccttag cccttgggat tatgcagcgg gaaatgtctt
    58561 attggaagag tttggtatgg taacaagcgg tctttttggt actcctttga catttgaaaa
    58621 aagggaatac tatttagcag ggacttcttg tgcatatgca gaaatcgcag accttttgaa
    58681 aaaagaaggc tgaaaaaaag gtagaaatca ttcacaaaaa tgataaaaac gagcaaaaga
    58741 ttaattttct cgaaaaaatg aaaacatttt actatatttc atgaaaaaag tctgctataa
    58801 ttagcagtcg agtaaaattt gccctgtcat aaagaaccaa taaaaaagga gttagttaca
    58861 ttgaattata gaaacgatat ccgtaacgtc gcaattattg cccacgttga ccacggaaaa
    58921 acaacattag ttgatgaact attaaaacaa tcagatacat tagacgcaca tacgcaattg
    58981 caagaacgtg cgatggactc aaatgcgcta gaaaaagaac gtggtatcac gattttagcc
    59041 aaaaacacag ctgtagacta taaaggtatt cgcgtaaaca tcatggatac tccaggacac
    59101 gcggacttcg gtggcgaagt agaacggatc atgaaaatgg ttgacggcgt tgtgttggtc
    59161 gtagatgcgt atgaaggaac aatgcctcaa acacgttttg tattgaaaaa agcactggaa
    59221 caacatatca caccaatcgt tgtcgtaaac aagattgaca aaccttctgc tcgtcctgag
    59281 catgtcgtag atgaagttct tgaactattc atcgaattag gagcagatga tgatcagtta
    59341 gactttcctg tgatttatgc atctgcacta aatggtacgt caagcttgtc agatgatcca
    59401 gcagatcaag aaccaaccat ggcacctatt tttgatacaa ttattgaaaa aatccctgct
    59461 cctgtcgata acagcgacga accattacaa ttccaagttt cattacttga ctacaacgat
    59521 tatgtaggtc gtatcggaat cggacgtgta tttagaggaa caatcaaagt aggagaccaa
    59581 gtagcattaa ttaaattaga cggaacagtt aagaaattcc gtgtaacgaa attatttggt
    59641 ttctttggac taaaacgtct agagattcaa gaagcaaaag ctggagactt gattgctgtc
    59701 tcaggtatgg aagatatctt tgtcggtgaa acagttactc ctgtggatca tcaagatgcg
    59761 ttacctatcc ttcacattga cgaaccaaca ttgcaaatga ctttcttagt taataattca
    59821 ccatttgccg gtcgagaagg taaattcgta accgctcgta agattgaaga acgtttgatg
    59881 gcagaacttc aaacagatgt atccttacga gttgaaccaa caaactctcc agatgcatgg
    59941 acagtttctg gtcgtggaga attgcatttg tctatcttga ttgaaaacat gcgccgtgag
    60001 ggatacgaat tgcaagtatc tcgtccagaa gttattgaaa aagaaatcga cggtgtaaaa
    60061 tgcgaaccgt ttgaacgcgt gcaaatcgat acaccagaag aatatatggg tagtgttatc
    60121 gagtccttga gcttacgtaa aggtgaaatg caagatatgg tccatacagg aaacggacaa
    60181 atccgtttga cattcttaac acctgcccgc ggtttgattg gttattcaac tgaattcctt
    60241 tcaatgacac gtggttacgg aatcatgaac catacttttg accaatatct gccaatgctt
    60301 cctggtcaaa ttggcggacg tcaccaaggg gcgcttgttt cgatcgatac aggaaaagca
    60361 acgacttatt ctatcatgag tatcgaagaa cgcggtacag tcttcgtaga accaggtaca
    60421 gaagtatatg aaggaatgat tatcggggaa aacagccgtg ataatgattt gactgtcaac
    60481 atcacgaaag caaaacaaat gacaaacgta cggtctgcta ctaaagacca aacatctgtc
    60541 atcaaaaaac caaaacaatt gacgttggaa gaatctttgg aattcttgaa tgatgatgaa
    60601 tattgcgaag taacaccaga aagcattcgc ttgagaaaac aaattttaga gaaaaatgct
    60661 cgtgaaaaag catctaaaaa gaaaaaataa tctgtaaaag gatgaagaga gaaaccagct
    60721 tgttataaaa aatagctggt ttcttttttt gtccaactct tttctgtgga gaagtcatct
    60781 ttgtcaatgg acataaattc agaaaatacg ccgaaagacg tttaaaagac ttttaaaaaa
    60841 cttatttcta gagagttttt gtttcataat aagataatgt ttcacgaaag gagatcaact
    60901 tgtccttcga agaaaatcga agtaaaatgg caagagaaag gagcgggaag atgaacgact
    60961 tattaaaaca atactttggc tatgatgagt ttagacctgg tcaaaaagaa attatccaga
    61021 aagtcattga tcaggaaaat gtattaggaa tcatgcctac cggaagtggg aaatcaatct
    61081 gttaccagct tccagcttta ctattagatg ggcttactgt ggttgtgtcc cctttaatct
    61141 ctttgatgaa ggatcaggtg gacgcggcga atcaattagg tatacccgcc acttttatca
    61201 atagctcgtt agatggttac gaaacagcta gacgcttcca agaaatcgat agacagcagt
    61261 accgtttact ttatatcgct cctgaacgtt ttatcatgcc ggattttatc caagcaatga
    61321 agcgatggaa cgtccgtatg atcgctattg acgaggcaca ttgtatctct cagtgggggc
    61381 atgatttccg cccaagttat ttacagatgg cgaaccagct agatcaactg ccaaatcgtc
    61441 ctgtaattgt tgctttgaca gctacagcga ctgtgcaagt agctgctgac ataaaaagac
    61501 ttttaaaaat tccagaaaac aaccatattc agactggttt tgaacgagaa aatctacgat
    61561 ttcaagtaat taaagatcaa aaaaaagaac aatatctaat cgaatattta aagatcaaca
    61621 aaaatcaatc tggtatcatt tatgcagcaa cgagaaaaga agtagaccgt ctctatcatt
    61681 tgcttaaaaa attcgatttt tccgtgggta gatatcatgg tggtctaaat gagaatgagc
    61741 gaacagaaat gcaagaagcc tttttatacg atcgcttgca gctgattgta gcgacaaatg
    61801 catttggtat gggtagaaat aaaagcaatg tccgttttgt tatccattat caaattcctg
    61861 gctctctaga agcatactat caggaagctg gtcgggcggg aagagatggt ctttccagtg
    61921 aagccatcct gcttttctct cctcaagata tccaagtcca aaagtttttt atccagcagt
    61981 cccaaagaga agaagggcaa aagcaaaaag aatatgaaaa attaaaagcg atgacagaat
    62041 acgtgtatat tgagtcctgt cttcagcaat acatcctaaa ctattttggc gagacaagca
    62101 gtccgtgcaa ccgttgtggt aactgtttag atgacagaga aatagtagaa gtaacgacag
    62161 aagcacagat ggttctttct tgcttaaaac gtatgggtga gaactatggt aaacaaatgc
    62221 tgatgaaagt cttagcagga tcgaaagaac aaaagctgca agctttaggt tttggacatt
    62281 tatctaccta tggactgatg aaaaaccaat cgcaaaaaga aacgatgcag ttaattgaat
    62341 atttgatatc gaatggctat cttctgacca tcaatggtga gtatcctgtt ttgaaagtaa
    62401 cagaaagagg gatacaagta ttgaaaggac aagaatctgt ttatcgaaag gaacccaaga
    62461 aagtccagca gctatcggat gaagaaaccg atacactatt tgaagtgctg cgggaactgc
    62521 gaacggatct agcatcagaa gcaggcgttc ccccgtatgt cgtattttca gattccacat
    62581 tgaaagaaat gagccgaata cgtccatcaa gcagattgga gatgcttcag ataaaaggag
    62641 ttggccaaag caagcttgat aaatatggcg aagccttttt atctcggata aaaaatgcgg
    62701 actctaacgt tctggataag tagaaagaac gaatacgtaa aaatgaataa aaacaactgg
    62761 ttaaatctgt tttttttgct ccttatgaaa atcaaatatg ttataattaa ggaattagaa
    62821 tgggaggtaa gcacagatgg attctttgtc gaaaaaactt gcgatccaag tattaaatga
    62881 tgaagcagaa cggatcaaac gattaatccg aaatcaaaac aacagtctct gtatctcaca
    62941 atgcaaagcc ttcgaagaag tggtagatac acagatgtac ggcttttccc ggcaagtcgg
    63001 ttttgctgtc cgtataggag taatcggaaa gaacgagggc cagctgatgt taagtgagct
    63061 agaacgagaa ttgaatcagt tatatagtga ggtttaccaa gaaatttatg ataaaaaaga
    63121 agttggcaag gaggaataga cttgcctaag aaagtgaaaa aaaggcatct attagactat
    63181 agcatcttga ttccctattt aattttatgt gtattgggat tgatcatggt atatagttct
    63241 acgtcgtatc tattattaga aaacggacaa aatccgtccg catcagtcat taaccagagt
    63301 attttttggg tgcttagctt gattgctatc gcactacttt ataaaatgaa aacagatgtt
    63361 ttgaaaaacc agcgtttgat catggcagcc atcgcagttt tgacgatttt gctgctgatt
    63421 gttgtgtttt ttggtaagga gatcaatggg gcgaaaggtt ggctgcaaat tgcaggattc
    63481 tcgatccaac ctgccgaata cctaaaaatc atttctatct ggtacctgtc tctgacttta
    63541 tctaaaagac aaaacagtgt acaaaaagat tttcttggga ctgtgaaacg tccacttgca
    63601 atggttatcg gacttactgc attagtcgct attcttcccg attttggtaa tgcggcagtt
    63661 atctttttga ttattttggt tctgctttta gccagcggag tcaattatgt gtatactttg
    63721 attgtaggag taggaggctt ttgtctaagt acttttacga tctggctgat caatatcaca
    63781 aacggaaaga tcttacccgg acgtttacag tatatctata atcgatttgc tatttaccaa
    63841 aatcctttct cagacgaatt aaataaaggg catcaactag tcaacggcta ctatgccatg
    63901 ttcaacggag gactatttgg caggggatta ggtaacagta tccagaaaaa aggattttta
    63961 caagaagcac aaaccgattt tatttatgca atcgtagtgg aagaactggg agtgattatg
    64021 gggattttga tattagcgtt gctattcttt atgattgtgc gcattgtcct tgtaggtatc
    64081 cgttcaaaag atccgttcaa ttcgcttttg tgcattggga tcggcgcaat gtttttgatc
    64141 caagtatttg tcaatcttgg aggaattact ggcgttattc ctttgacagg gatcacgttc
    64201 ccatttttaa gtcaaggagg ctccagtttg ctgatgcttt cgatttgtgt cggctttgtc
    64261 ctcaacatca gtgcggatga aaaacgcaag agcttaggtt tataataaaa aaagatgtag
    64321 gagtggttcg atgaaaaaag ttttagttgc taacaggggt gaaatcgctg tacgtgtatt
    64381 tcgtgcttgt acagaattag gaattaaaac tgttggaatc tatgcagaag aagatgaata
    64441 ttccgtacac cgtttcaaag cggatgaagc atatttagta ggacaaggaa aaaaaccgat
    64501 tgatgcgtat ctagatattg aagggatcat ttctatcgcg aaagaatgcg gagctgacgc
    64561 tattcatccg ggttacggtc ttttgtcgga aaacttgaat tttgcgcaac ggtgcgaaga
    64621 agaaggcatc atttttgttg gacccaaact gcatcattta gatatttttg gagataaaat
    64681 caaagcaaaa gctgcagcta tcgaagcggg gattgcttcg attccaggca cagatggacc
    64741 aatcgcttct atagacgatg ccttggagtt tgcgaaacaa tacggttatc cgattatgat
    64801 caaggcagct ctaggcggcg gcggacgcgg catgcgtgta gctcacgatg aaaagagtgc
    64861 aagagagggc tacgaacgtg cgaaaagcga agcaaaagca gcctttggta gtgatgaagt
    64921 gtatgttgaa aaatacatcg ctaatcctaa gcatatcgaa gtacagattc tcggggatac
    64981 gcatggaaac gtcatccatc tttttgaaag agattgttct gttcagcgcc gtcaccaaaa
    65041 agtagtagaa gtagcgcctt gtgtctctat gaatgaacag caacgtcaaa aaatctgcca
    65101 ggcagctgtc caattgatga aatatgtcgg gtatgtcaac gcaggtacag tagaatttct
    65161 tgttgaagga gatgattttt actttatcga agtcaaccct cgcgtccaag tggaacatac
    65221 gatcacagaa atgattacag atattgatat cgtaacaacg caactgttga ttgctcaagg
    65281 tttggatctg cataaagaaa tcggattgcc tcagcaagaa ggaattaaat taaatggttc
    65341 agccattcaa tgccgaatca ctacagaaga cccgttgaat aactttttac cagacacagg
    65401 gaaaatcgat acgtatcgtt cacctggtgg ttttggcgta cgtctggatg tcggaaatgc
    65461 ttacgcgggc tatgtagtga caccgtattt tgattcattg ctagtaaaag tatgtacgca
    65521 tggtgctacc tttgaaacag ccattcagaa aatggaacgt tgcttgaaag aatttagaat
    65581 ccgtggagtg aaaacaaaca ttccatttat gctcaatgtc atcacacatc ctgaattcca
    65641 atcaggaaat gcaaaaacaa ccttcattga tagtacagca acattatttg aatttcctcg
    65701 actacgagac cgcggaaaca aaacgatgaa atatatcggt gaaattactg tgaatggttt
    65761 tccaggtatc gaaagtggcg aaaaaccatt ttatgaagaa ccacgtatgc ctaaagatct
    65821 aatcacaaga actgattacg taacggctaa gaatgtatta gatgcgaagg gtgccgatgc
    65881 tttggtcgaa tggatcaaag gacaggaaaa tttgttgttg acggatacga catttagaga
    65941 cgcccatcaa agtctgctag caactcgtgt tcggacaaag gatttcaagc agattgcacg
    66001 tttgactgga gaaggtcttc ctgaactctt ttcaagtgag atgtgggggg gagcaacatt
    66061 tgatgtggct taccgctttt tgaatgaaga tccttggcaa cggttgagaa aaattcgttc
    66121 tttaatgcct aatacgttgc tgcaaatgct tttcagaggt tcaaatgccg ttgggtattc
    66181 taattatcct gacaatgtat tggtggaatt tgtcaaagaa gcagcagcgc aaggaatcga
    66241 tgtatttcga atctttgata gtttgaactg gactccacaa atggaaaaaa gtatccaagc
    66301 tgtacgggat actggtaaaa tcgcagaggc agctatttgc tatactggcg atatcaacga
    66361 tccaagtcgg gcaaaataca atgttcagta ttataaagac atggcaaagg aactagaaca
    66421 actgggtgcg catatcattg caatcaaaga tatggctggg ctgcttaaac cgcaggcagc
    66481 ttatcgtttg attagtgaat tgaaagaaac gacagatctg ccaatccatc tgcatactca
    66541 tgataccagc gggaatggaa tcatcactta ttctgctgct tcaaaagcag gagtagacat
    66601 cgttgacgtg gcaatgagtg caatgagtgg gaatactagt cagcctagca tgagcagctt
    66661 gtattatgca ctggtcaatg gtccacggct gccagaaatc acgattgaaa atgcacagaa
    66721 attaaaccat tattgggaag atgtgcgcat gtattacaaa ccgtttgaaa acggcttgaa
    66781 tgctcctgaa acagaagtat atatgcatga aatgccagga ggacagtatt cgaatctaca
    66841 gcaacaggca aaagctgtcg gattaggtca tcgctgggat gaaatcaaac aaatgtatca
    66901 tactgtcaac ttgatgtttg gcgatatcgt taaagtaact ccatcatcta aagtagttgg
    66961 agatatggca ctatttatgg tccaaaatga tcttacagaa gaagatattt atgaaaaagg
    67021 cgaaacacta agtttccctg aatctgttgt gactttcttc caaggagaac tagggcaacc
    67081 cgttggcgga tttcctaaaa aattgcaaaa gattattctt aaaggcagac ctgcattgaa
    67141 tgaacgtcca ggtcttttgg ctgaatcagt cgacttcaac gaagtaaaaa aagaattggc
    67201 agaaaaaatt ggctatgaac caaaacaaga cgaagtatta agctatttga tgtatccgca
    67261 agtctttttg gactatcaaa aagcatataa tcaatttggc gatgttacat tactggacac
    67321 accaacattt ttccaaggta tacgtttggg tgaaacaatc aatgtacaaa tcgaacgcgg
    67381 aaaaacgctt atcattcgtt tagatgaaat cggagaaccc gatatcgaag ggaatcgcgt
    67441 actgttcttc aatttgaatg gacaaagacg tgaaatcact atcaaagata attcgatcat
    67501 cagtacggtc caaacccgat tgaaagctga accgacaaac cgagaacaaa ttggagcaac
    67561 gatgtctggt tctgttttgg atgtattagt gaaaaaaggc gataacgtta aaaaaggtga
    67621 tacgttgatg attactgaag cgatgaaaat ggaaacggcc atcgaagcac gttttgacgg
    67681 agaagtcgca catgtatatg tgtcttcagg agacactatt tcgtctggtg accttttgat
    67741 tgaagtgact gagaaataat aagcgaaagg tggggaaaca tgaaaagact gggtttgttt
    67801 tggctgattc tgctattagt tattgtggca ttctacatgg aaccagtctt gtttccgcca
    67861 aaacttgaag tgaaggaaaa ctctgatcaa caaatatcaa accaaatgac aacgtggaaa
    67921 taccaggagc ttaaagcaac tggtttttct acttatatcg gaaaaccgat cgatcagctg
    67981 gaaaaggatt ttggccaagc ctatgatcga ttaactagcg gatttggttt tgaaacaaga
    68041 tattatgaaa ataaagctag tcatctcaca tttgaagcga acatccaaga cagcagagtc
    68101 acaactgtta aagtactgca aacagggcct gctgatatcg cgccgtttta tttagggatg
    68161 acgatgcaag atcttacgaa aatcactact atctatacta atttcacttt tgagtaccat
    68221 gatacagaag ttggaatcga actaatggaa gaggatatga attatcgtcc gctaattgct
    68281 tttgataacg acacttttgc tattttattt tttgatcaaa caacaaacgg cctattttca
    68341 gttgtgtatt tagataaaga tagtcttttg aaactattgc catatcaagt gtttggtgaa
    68401 ggccttccac attatcaagc agataaatcg gctgattggg aatcaatcaa tcgcgttaaa
    68461 gaacgaaaaa gtacgacttt attaaatatg cttagaagag aagacgaact tcccatatac
    68521 aatcaaacac ttgcctttca aaaccacagt cagctgctac tacatgattt tttgacaagg
    68581 cctgaggaaa tattgtcaga ggaacgtatg gctgattggc aaaaatcgct aggcagtgct
    68641 caaacgacag tgaaattctc actgacgaat gatgaattgg agaagttaat cagtaaacaa
    68701 aaattagaaa atactagtgg gctatttatt catccggcga ttgacgctac tttttcgttt
    68761 ttatattggt acagcgatcc ttacaaccat gaccgtttca tggacccggg aacggattct
    68821 gtaggcattg ctttttctaa agaaaatatg ttagtcttat tgcaagaaga aaacggagaa
    68881 agtagtgata gcagtgatcg ttaacgaaga gctgtttcaa ctggaggatc aatgcctcca
    68941 agtcgctgaa atgataaaaa agagtaaaac gatggcttct tatcttgaac ataaacagtc
    69001 aatggaagaa tctgcaaaag tttgccagtt gaaagaagcg ttcttgtcta agaaagaagc
    69061 atttgaaaat gtagcggcat atggtgagta tgcacctgat tatcgtgaaa aaaaacgagc
    69121 tgttcgaaaa gcaaaaagac agcttgatat ggatgagcat gttgcagctt tccgatatag
    69181 tgaaacacag ctgcaaagtc tgttggatca aattgtccaa gtacttgccg aagaagtttc
    69241 taatgaaatc aaagtagatg caggtagccc gttttttgaa acgaaaaaac actttggatg
    69301 cggaggtaat tgtcatgcaa ttagacaata gtgaatttga aataacaaaa cgacgcgggc
    69361 tgatcgtatg ggtctacagc ttaaaacaat taaagaatct gaaaaagttc ggcttgttgc
    69421 attatgtctc aagaagaatg aaatatgtcg tgctttactt aaatgaagag acattggaag
    69481 aaacagaaga acgaatccgt aaattacatt ttgttcgaaa cgtagaacgt tcttaccgac
    69541 cggatatcga aatgaatttt gccgaaaaaa taggaaacaa aacagtatta aaagacgaag
    69601 gtttcgaaat tgaagagcta aatacagaaa tccgattagc tgaacatctt taaaaatctc
    69661 ttatgagcag tttttaaata aaaaataact tggataacga tcgatttttg atcattgtcc
    69721 aagtattttt ttggtatact agtaccagta ccatttctaa ggagtgagta gatgcggata
    69781 atatcaggaa attatggcgg gcgccgttta aaaagtttag caggggcgaa caccagacca
    69841 actacagata aagtaaaaga atccatattc aatatgattg gaccatattt tgatggagag
    69901 acagtattgg atctgtttgc aggaagcggt ggtttagcta tcgaagcagt atctagaggc
    69961 tgcagtcatg cggtatgcgt agacaaaaat taccaagcgc taaaaatcat caaagaaaac
    70021 atcgaaatta cgaaagaacc agagaaattt accacaataa aacttgatgc ggacaaagca
    70081 atcgaacggc tagcagcgga gaaacaacaa ttcgactact tgtttcttga tccgccatat
    70141 gcaaaacaaa aaataatcga tcaaatccat aaaatggaag aactgggact tttttctaaa
    70201 accgcagtta tcgtatgcga aacggataaa acagtcgaat tgccagaaac tgtggctgga
    70261 ttccatcaaa taagaaaaca gatttatggc ataacggccg taactatcta tagaaaagag
    70321 ggaaatcaat gaaacgtgca ttattcccag gaagttttga tccttttaca aaaggtcact
    70381 tagatacggt ggaacgtgcg gctaaattat tcgatgaggt agtaattggt gtttttatca
    70441 atacttcaaa gaaaagtttg tttcccccag aagaaagaat gacattgatc acaaaagctg
    70501 tttctcatct tcctaatgta aaagtcatgc atcaagaaaa tcaattgacg gtagaaacag
    70561 caaaagagat tggtgcagat gcgttgatca gaggcatacg aagtatcaaa gactttgaat
    70621 atgaacgaga gattgctcag atgaatcatc atctatatga tgaattggaa actgtcttct
    70681 tattagcaaa accagaatat agtcacgtga gttccagtat tttaaaagaa gtactgcact
    70741 ttggcggaga tgtgagcagc tacttaccgc cagtgatcaa cgaagcttta gctggaaagc
    70801 gtgaatcaaa tgaaagctaa acaatggttg aaaacagtac tgattatcat atttggaatg
    70861 ttgatcattg gatttgtagt agttcccttg ccgtattatg tagaatcacc gggagccacg
    70921 atcgatctga aagaactaat tacggtcaat gataaggaag ataaaggttc tgggtctttc
    70981 tctcttacct ctgttggtat caggcaagct acaggtttct tagctttaaa agctaaaatg
    71041 accccttttg aagaattgat cagtgaagaa gaattgactg gtggggcgac aaatgaagaa
    71101 tataatcaaa tgcaacagta ttatatggat tcttcccaaa atgcagcaat cgaacaagcg
    71161 ttaaaacttg cagacaagcc ttataaaatg gaattcaaag gcgtatatgt catgagtgta
    71221 gagaaaacat cgaatttctt tggcaagctt tcagttggag atacagtaac aaaagtagac
    71281 gggaaaagct ttcaaagtac agaagcattt atggattatg taaaaagcca aaaagttgga
    71341 caaacaatcg aaatcagtta tttgcataat ggtgaagaaa aaacagcttc tggtgatctg
    71401 atcgagttac caacagataa aaaggcagga ataggtatca cgcttactga ccataccgag
    71461 atcgaatcag atacagatgt tcgtattaat tctggctcta tcggtgggcc atcagcggga
    71521 ttgatgttca ctttagaaat ctatgaacaa gtcactggta aaaacttgcg acatggtaag
    71581 caaattgcag gaactggaac gatcaacagt gaaggagaag ttggccgaat cggaggaatc
    71641 gataaaaaag tggcaagtgc ggataaagct ggcgtagaga ttttctttgc accagatgat
    71701 acgatttcag acgatgttaa gaaagaatat cctgaaataa aaaccaacta cgaagaagca
    71761 aaagctgccg ctaaaaaatt gaattcctca atgaaaatcg taccagtaaa aacagtacaa
    71821 gaagcgcttg actatctaga gaaaatgaaa tgaaactaaa taattaaaga ggggttgtga
    71881 cacgagttct gtcacaaccc ctctttttcg tcaaaaatct tcacgataaa aataaaaaca
    71941 aaagaaaaaa ttgacgtaat tagatgttga agggacgatt ttgccagagc tcactgtttc
    72001 ttcaatttta aatgaaagga gtaatgaatg atttttactg gtcattcttt gaaaaaagaa
    72061 caatgataga aaaaatcagc aagaaaatac tagcttcacc caaattgatc atttggatgt
    72121 ctatgatagt tcttatcttt tgtatcgcaa gtggtttttt attatcaaat ttgctatttt
    72181 atagagaaac agaagagact gctgcaaaag aaatactttc ttcgtttagt tccagtggag
    72241 aagatccatc agctgaagga aacgatgtag aagaggatgc tcgtccaaag gtcatgtaca
    72301 ccgatatcaa aggaagtgtg aaggagcctg gtatctattc cttttcttca gaagaacggg
    72361 tctatgatgt actaaagcgt gcaggtggat tattagaaga agcggatagc gatcgaatca
    72421 acttttctgc gaagatagaa gatcagcaag tcctatatat ccctgctgta ggtgaagagc
    72481 tgccagaaca tcttgatcag ttggcatcct cggaaggaaa acagcctaca gcagattccg
    72541 agcctcccaa aataaatatc aatacagcca ctccatcaga acttcagcag attcctggga
    72601 tcggatcagt caaagcgcaa gaaatcattc gatttagaga agaaaacgga tccttccaga
    72661 aagtggaaga cctgcaggag atttctggta tcggtgaaaa gacagttgaa aaactaaaaa
    72721 acttcgttac aattaaatag aatgattcaa aatcgactgg cacgagcaat aaatggacgc
    72781 taatggatac taagaataat ccaattctaa gagcttggca ggacgaggag gtagtatttt
    72841 tggataggaa atagcttgat tgttcgcaaa gaaacattaa aaaaaccaat gctgaatgtc
    72901 tatctccaaa ataaaatatc tgggattcat attatgaata cggctgtcag cggcaataac
    72961 agtcaagctc tacgagaacg ctttgccaaa gatgtactta gctatacagc agataaagta
    73021 tttattctca ttgggacgaa tgatctagca gagcataaac aactttctaa agaaacgtac
    73081 caaaaaatct gcagtggatg atagttcagc tgaaaaaaga ctatagttct gatcatgctt
    73141 tctttatcac gccaccagca gtcgatgaga caaaacaaaa atatcggaat aacaagttga
    73201 tcaaagaata tatctctgtt ctcacagaag tagcaaaacg ccatgattgt gaagtatcga
    73261 tttttatacg gaatttcttg aacaaatgga ttcgaagaat ttttataatg ggctaatgga
    73321 tgacggactt catttcggca gtgaagggta ggatcttttg tcagacagga tgattcgtta
    73381 tatttaaaga atattttgtt taagcaatga gtacttttta atcaacttga aaaaacggag
    73441 gaatataaaa catgttagaa aaatcttcaa aagcatgcga tacgaataaa gaaaaagtta
    73501 ctgataagtc acataatgaa cgcattcctt gggaccagta ctttatggct caggcagtac
    73561 tgttatcttt acgtagtacg tgtacacgtt tagaagtagg agcgacactc gttcgagaaa
    73621 aaaggatcat tgctggcggc tataatggag cagtcagtgg agatgtccac tgcatagatg
    73681 aagggtgtta cgtcgtggat ggacactgct tgcgaacgat ccatgcagag atgaatgcac
    73741 tcctacagtg tgcaaaactt ggtatcccga cggaaggttc agaaatctat gtcacacatt
    73801 ttccatgttt ggcctgtaca aaggctttgt tgcaagctgg tgtgaaaggg atcaattatc
    73861 tccatgacta tcgaaatgat ccttatgccc aagcgttgat cgaacaatta ggtgtatctg
    73921 tacaccaagt tgctttagac tcacagcatt tttcaaaact tcaaaatgaa ttaacaggaa
    73981 aacatgtcta gcgttttaga aaggcatgtt cgaaatcggt tgatttttcc ggcaattacg
    74041 tcgatgatta tctgtttgtt gtattacact gacaattggg gttatcgttt gcttcttgcc
    74101 ggaatttttt tatggttttc gctaaaagaa ggacgtttta tcgcgtactt gtgtattttg
    74161 tgtagcataa cggtatccat ttcttatagg ctacaagagt attcattttt agaggaaaaa
    74221 acaacatctg cgcaaattac tgtatttaca gatacgattc gtgcaaatgg taattttttg
    74281 acaatggaag gaaggttatc agagaataaa caaaagctcc agctttctta tcaagtaaac
    74341 acagaagcag aattgaaaac atggcttaac ttccgaggaa agggaataga attgactgct
    74401 gaaggcgagt tcatctctcc agcaaaaaag cggaatcttt ataattttga ccaagaagct
    74461 tacttcagga accatagaat ttctggacgg ttccaaattc aaaagattga acagatcacc
    74521 atgcaaaatc actggcgaaa ctggcttcag agaaaaagag gatcttttat ctcctttgtc
    74581 caatctgaat ttccgcaaaa aacaagtgta tatattaatt ctttattatg gggctataaa
    74641 gatgcaggat tcagagaacc agaagaaatt tttagggaga gtggtttgct gcatctgttc
    74701 agtctatcgg gtctacacat ccaattttat ttagggtggc tgtattattt atttcgacgt
    74761 atcggatggc cactacacgt cagtattatt ccgttgagtc tactaactat ctgttatgtt
    74821 tctattgcag gaagttctat ttctgttttg cgtgctagtt tgctgttttt attgcgattg
    74881 ctagtcaaat tgctgaataa gcattattcc accatggact tatttgcagt tgtcttttgg
    74941 cttcttttac tatttgatcc tcgatttctt tttcatgcgg gtggacagct tagttttttc
    75001 atgagttttt tgtttatcct gatttctttt gatggagatt ggttgaaaaa aacggcctct
    75061 cacgtcctgt ttactatgat cacgatgccg ttgattgtat ggcattttta tgagtggcct
    75121 attttaggta gtctttttac attactgatt gcaccggtat tcaagtttct ttttcttcct
    75181 ggtgtgttat ttctcacact cttcaatcgc tggctgccgg aaactttact tttgttgata
    75241 gaagagggat taatcttatt tgagcgaata atcgattttt cttcagggtc gtctctcatt
    75301 ataggacgtt tgccccttgt gctatctggg atgtatattt tcggattact gatttgtatg
    75361 gataggttga aagaacaacc tgtgaaacac ttgttttatg ttggtctttt ttcttttatt
    75421 tttttgactt tgccattttt acgcttttct tcaacgatcg cttttatcga tgtcggtcaa
    75481 ggagacagta tctttttgca aagtcctttt cgaaaagaaa cgattttgat cgatactgga
    75541 ggtcagttac actttgaaag agaaaagtgg gcgcaaggta tgatacgtcc tcctgctgaa
    75601 agaaatatcg ttccatatct aaaaggtcag gggataagtg taatcgataa actcatcttg
    75661 acacacgacg atacggatca tgtgggagaa ttacccacgt tatctcagca ttttactatc
    75721 aaaaaaattt atatcggttg gggcgctgga cgaaatgagc cattacaaag gcatttatct
    75781 gaagctcaaa aaaatggtac tgagatcatt gaaatcaaac atggggacag gatcagcggt
    75841 tattatgatc tttatgtatt gactcctttt gaaaagggag agggaagaaa tgaagattcg
    75901 attggtctat ggatggaata taacaatagg cgctttttat ttttaggaga tttgaatcaa
    75961 gcaatggaaa aacaattgct tttgatttat cctaatctga aagccgatgt agtcaaatta
    76021 ggtcatcacg gtagccgtac gtcaagtaac acagattttc tttcccatat tgaagcaaaa
    76081 catgggatta tatcctgcgg cgtaaataat cgttatggtc acccgcacag cgaagtattg
    76141 gagacactag aagaaaatca gataaaaaca tggcgaacgg atcaacaagg aatgatcacc
    76201 tatcgctggc atccagtttt tcatcctcat gggctagtgg aaacaatgat agactagtaa
    76261 ttctcatctg ctcatggtag gataattttt gaaagtggtg agtaatttga gtatacaagc
    76321 agagttacaa aaaatacgta aagaaaaact tgcatcttgt tacttgattt taggaacaga
    76381 aaagtttctc caagatcaag ttcggacaga aattgtcaaa aaaatccaat tagagggcga
    76441 agatgactta aattttttaa gttttgacat ggaaaatgca agtttagatg aggtagtagc
    76501 tgaagcagag acgttgccgt ttttcggaga tcaacggtta gtattcgtag agaatcctta
    76561 ttttttaaca ggtgaaaaag taaacaatgg aatcgaacaa aatactgatt tattgacggc
    76621 ttatttgaaa gaaccattag aatcgactgt attagtattc tttgcgccat atgaaaagtt
    76681 ggatgaacgg aaaaaagtaa cgaaacaatt gaaaaaaaca gcaattatca tcaatgtcca
    76741 acagttgaat gaaaaagaag tacgtcaata tctgatgaat accttagaga attcctcaat
    76801 caaaatggaa cgaagtgcaa ttgatttatt cttgaggttg accgacttag atttatccaa
    76861 aatgatgaga gagttacaga aattggtcct ttatggacaa aatcaacagc aaatcacggt
    76921 aagagaagta gaagaattag ttcctaaaac gttagaacat aatatttttg acatgaccca
    76981 atatatttta aaagggaaga cggaacaagc tttgcgttta tacgaagatt tagttatgca
    77041 aggggaagaa acaatcaaaa ttaatgcgat tttgctttct caattacgtt tatttttaca
    77101 gacaaaattt cttgtaaaga ttggttatca gcaggcaaat attgctgaaa cattgaaaat
    77161 ccatccatat cgtgtaaaac ttgccatgca ggaagtaaaa aaattcgatg aacatttgct
    77221 ggtacagttg tttgatcaat tagttgagat ggattatcaa atcaaaacgg gacaaatcga
    77281 aaaagaatta agttttcaac tattcgtttt gcgcacaggg cagttgttaa gaaatcgata
    77341 agaagaaaga cgagggcaaa gcatgcggga aggtcgtttg tttttgtcct ttttttgaca
    77401 aataaaaaaa tcggccgaag ccgattcttt tatttagcga tttttttgct taaacgagat
    77461 ttgtcgcggt tagctttgtt tttgtggatt agaccttttg attcagccat atcaatagct
    77521 ttaacagctt ctttatataa cgcatctacg ttgtcagcac ctgaagctac agcatcttca
    77581 aattttttga ttgcagtacg catagcgctt gtttgagatg aatttttcac attagcgttt
    77641 tcgcttgtac gaacacgttt gattgcagat tcaatgtttg gcattagttt cacctccgat
    77701 aacttaagtt cttacgcgtg ttaccgcata attcaacatt cattattata cctaaaggca
    77761 gcgtgctttg caatatgaac atgacaagtt tttttcctta acagtctttt attaggattt
    77821 tttttcagta aaaacggata gtacaagctg aaaaaaatca aaaagacgct attgtgggag
    77881 gcaatagcgt caaaccaaac tagattttta tttatctatt taaacaaagt ttgaatggga
    77941 atgtttggta ctaagttatt atataacaaa gagaaccgtt tgcaaagttt tttttgaaaa
    78001 gggatacgat tccctgttgt tctttgtttt tctattaaga aactgcagtt attttataac
    78061 cagtatcctt tgatcagtaa aggctattct ggtgtaccga ttattttaat gtattcatcg
    78121 atatttttta tcaacatttt ttttatgacc aactggttcc gacggttcca tttgccactt
    78181 acttccagca catatttatt taggggcaaa cgtaagatat attttgccaa atagcgatct
    78241 ttaagcaggc cattgatcac acggtcctca agctgcaagt tgatcccagt cagcatcatt
    78301 ggctgttctt gtaaaacgta cgtatcaatt aaaagacctt caaaagtttc cacaagcgtc
    78361 ttcctttctt ttcaaagtaa cctgaaaaca ggcactaatt cttccatttt gatattcgtt
    78421 gaagtggatg cgatcattct ttcttttgtc cactgtaatc tagtataaca aaaaagagca
    78481 gaagagccaa aaagaaaaaa gagcatcgaa ttctatagga agtctcattg gcacggccta
    78541 aattattaca aaacattgat taaaaaaagc ccctgcatcg caggagcatc ccctatatcg
    78601 ttttaatagg tcaatcaaaa agcagtatca aacacatttt gtatcaaatc aggaaataat
    78661 agataagcta agcccagaat caaaagtacc gctagaagaa accagccgat tgttcctatg
    78721 aaatacttta atttttcgaa cattgtatca cctcgttgtc agtatatcac ggatcagtaa
    78781 attgggggtg ttaagaatct cctaaaatag acaaaatttg ttctattttc ctaaagcaaa
    78841 tacttgtaag atacagtaag tgataccaga agcaatgacc ggtccggcgg cgattcctct
    78901 taagaagaca acacctaaaa tcgtgccgaa aacaagtgca acagtgattt gtggatcaga
    78961 agcaatcaat cctacaccct tggaagataa gacagccact agcccaccgc aaaaaacagc
    79021 tacccagcca ataggggatt taaaggcttc taatagatca cgtagaccga tttctcctgt
    79081 tgcgataggg attagaatag ccgctgtgat gatcgtcacc ccaatattga ttcctttgcc
    79141 ttgaagccaa gggaaaaagg aacgggaggc tggtatgagc ttcataatca aaacaaaagc
    79201 tgccgctatc atcagacttt gatttttagc taaaattgct acaagtaaaa taattcctaa
    79261 aaaaagccaa ctttccatga aatatattcc tcactttctt cgaaacaatc ataacatgtt
    79321 tttagaaagt tacaaaagta ggaattcatc cttcaagacc tattcataag ctgttttttt
    79381 cataaaataa acaaaatcat aaaaaaacac tttgcttatt tgacagaaga cagccgcgct
    79441 ttgtatagtg gacaagactt acattttttt gaagaatcag aaagatcagg taaaggtctt
    79501 agtaaacgca agccattcag aataaccaat attgtgcttc cttcgtgtcc tacaactcca
    79561 agaggtagat ttaaaaattg caggaagtta gaagcaatca acaagagaat aacaagaatc
    79621 gaaaaaataa tattttgttt gatgatccgc cgcattttta aagatagccg atgactgtag
    79681 acaaatttat ttaagtcgct tttcattaag acgatgtctg cgatatccat agcggcatct
    79741 gtcccttgcc ccatagcgac acctaaagaa gcggctgcta aagcaggcgc atcattgact
    79801 ccatcaccaa ccatcgcatt tacttggtaa agttcattct cttttttgac tagttgtgtt
    79861 ttttcttccg gagtacagct tgcatagtaa tgttcaatcc ctacttgttc agcaatggcc
    79921 tttgctgtgc cagaatggtc gccggttatc atacttgtat ggatgttttg ggatttaaag
    79981 taggaaatta cttgttgggt atttgctttt ggaatatcta gcagacctaa aacagcaatt
    80041 aactgctgat ctttagaaag ataaatcacg gttttgcctt gattttccaa acgttcgatc
    80101 atttccgcaa tctctttgct gattatcatc gtctcaggat catatgcgtg cttgccaact
    80161 ttccattgcg cacctaaata ggtagtttgt aatccaaaac cagtaatttc ttctattggt
    80221 aagtattgga tttcttcagg tattgtgcaa tcgaaatatt gcaaaatcgc atgagcaagt
    80281 ggatgcgtcg ttttttgttc catagcaaca agaagttgtt gtgccaaatc cttttcatca
    80341 aagaaaaagc tgtcagttac aactggtttt cctttagtga gcgttcctgt tttatcaaag
    80401 gcaatcgctt ttaattcaga aagcttttct aaatggatac cgcctttgat taaaatccca
    80461 ttttttgcag aatttgaaag agcagctaga gaagctggtg tagcagatgc gacaagcgca
    80521 caaggagaag ccacaactaa taataccatt cctcgataaa agctttcatc ccaactccaa
    80581 cctaggaaaa agtgggggag aaggatcatt agaggaacag caagcaaaat caattttaca
    80641 taattatttt cgattcgttc gataaatgaa gctgtttgag ttggcgtatt ctgcgcttct
    80701 tctactaatt ggataatctt agcaaagaca gtttcggaac tcgtttttgt tactcgaatc
    80761 gtgatgggat ttccttgatt cagcgttcct gcatacatct catcgcctaa atatttttct
    80821 acaggcacag attcaccgct taatgcagac tcatcgatcg ttgcctgtgt gctttctaaa
    80881 aagccatcta tcggaacagc tgctccttta gcgacaaata ccaagttatc cacctttagt
    80941 tgagaaacat ctacttcttg catttgtcca ttttctttta ataattgggc tttttgtggt
    81001 tgaagattca tcaaagcagt aatttctttt tgacttttat tagttgtgta ttcctctaat
    81061 gcaccgctta aacaaaagat gaatgtcaac attgctcctt caaagtaatt accgatcaaa
    81121 caggcaccaa tagcagctaa agccatcaat aaatccacat tcagtgtccg atcattccac
    81181 aattctttca agccttccga tgtttgttta tatccaccga tgataatggc actgatataa
    81241 aaaagtgggg tgatggtaag agagaatcgg tcgaagataa aaccgaagat cataaataaa
    81301 aggcagccga ttgttgctgc aaaagctttt ttctgattag tcatcgttat tagacctcct
    81361 tgtcaaaaca aggatagcat aataaaaatg taattgataa taataacagc taaatgagaa
    81421 cgataatggt tatcatttgg tgattaagct tgatgttgtt tttattattt ataatgatta
    81481 ttattaaaga aaataaaaaa ccagaacatt tctcaaataa gagaagtgtt ctggtttttt
    81541 ctacattgca ataaaccaat aaccaatcaa aatgatacca aggataatac gataccagcc
    81601 aaaagcggta aagtcgtttt tcttcaaata gcttagtaag aatttgatag ctaagacgga
    81661 aaccacaaaa gatacgaatg ttcctacaag aagaacaaca gtttcttcca ttttgaatga
    81721 attcccttca gctaaatatt tgacgatctt caagccgctt gcgccaaaca tgacaggaat
    81781 ccctaagaaa aatgaaaact ctgtagcgac aaaacgcgaa gcaccaatca agatagatcc
    81841 taggatcgtt gcgccagaac gggatgttcc gggaacaagt gccaagactt ggaataaccc
    81901 aacaagaaga gctgcttggt acgtaaagtc attcagagaa gtccaacgag gtgttttgtt
    81961 tttgttgcgt ttttcgacaa taataaaggc aataccgtaa acgatcaaaa caatggcaac
    82021 tggtaagaac ttgtggaaat ttgcttctaa ccaatcatcc aaaggcaaac caatgatgat
    82081 ggctggtatg caagcaacga tcactttaaa ccaaagtgtc cacgtatctt ttttttctac
    82141 cgttgattta cttggagaaa atgggtttaa cttgtgaaaa taaagaacga cgacagccaa
    82201 gatcgcccct aattggataa cgacattgaa catcgacata aattgtgaac tggcatccag
    82261 tttgatgaat tcatctgcta ggatcaaatg accagtacta ctgatgggca gccattccgt
    82321 tattccttca ataataccga gaatcactgc tttgataata tttgcaaaaa acataaattc
    82381 cttccttccc aattaagata catcttatag tataccgtta ttttttgaga aacccaatct
    82441 gttttttaat attaagaaaa acttgagaaa taaagcagat aagtacacga agagaaaaaa
    82501 gaagacaaag ccctcgttca gactttgcct tttatgattc tctggtaaaa attaaaatat
    82561 ccccattata gaaacgagtc gcgactatgt gttttcccgt tatcgatata agacgtatca
    82621 ttgatgccgt ggatagaaaa tcgaccgttt gcataagtga cctttgttac gctgccattt
    82681 aaaagcccag cacgaacagg ctgtttagga tcgatcagat taagcaaaaa ggcgatcgtc
    82741 aaaccatgag atacgactaa aacatttcca ccaccatttt tttcgcagtg atgggcgata
    82801 tcttcaaatc ctgtccatac acggtctcgc aatgtttcat aagtttccgc ccacccagcg
    82861 gtatctaagt tgtatacagc attagcaatt tgttcaaaag aaacttctgt ggtaaacatt
    82921 tcatcatatg ttttaaaatt caatacacga gggatcacac cccacatttc catgtcatat
    82981 ccaccttcaa gagacccgaa acaccattct ctaatccttt tttcaataaa ataaggaatt
    83041 tcttttccct tagaatgttc tcctagaata atacgggcag tttcgattgc acgaccactg
    83101 tcactagaat aagcaaatga aaagtcgaca ttttttaacc cgcgacctaa ataatgaatg
    83161 ccttcttgtc cttgctttgt gaggggtgta tcacaccagc cttgtactcg ttcaattgta
    83221 ttgaacatcg tttttccgtg tcgtacgata taaagtgtag tttctgtcat tttattctcc
    83281 tcctaagtcg ttttaacgat tgaaaaaagg atttgtcctt ttttcctgtt caatcgtcgt
    83341 tgcatcgcca tgtcctggat agactgcaaa ttcatcaggt aatacaaaca gctgggtccg
    83401 aatactatga agtaattgtt ctaaattccc tgtatacaga tcggttctac cgatacttcc
    83461 tctaaacagg gcgtcgccag aaacgacaaa atcatcaaaa ataaagctga cgcttcctat
    83521 agaatgccct ggggtaggga cgacgcgaaa agacatgttt cctaaagtat aagttttcat
    83581 ttcaaattca tattctgcag gcgagacaat aacatcagca atatcatcat gtctaccgag
    83641 tccagaaaga ttcaaaatcg gatcacctag ccatttttgc tctagtgggc tgacataaac
    83701 tgggatttga taatacgcgc gtaaaggttc cactgcaccg atatgatcgt agtgagtatg
    83761 ggtaagcaaa atcgctaccg gctgttggtt tgtttttttg atttcttgtt tgattcgttc
    83821 cgcatcttct ccagggtcaa tgatcaaaag tgcttcttcg ttgtagacca aataacagtt
    83881 ttcttcaatc attcctgttt ttaatctttc gatatgcatg tgcattcctc cttgatagcc
    83941 aaaacttctt tcatccatta gtataacgca ttcattgcta ggaaacaaaa acaggtactt
    84001 atttctcttt acttatctga attatcagac tatatgaaaa gtatttggat attctaaaga
    84061 gaaggaaagt aagttttcat agcattttaa tatgtccttg ttacattaga ttcatccaaa
    84121 aatccaaatt ctatatccta tatccctgcc taatcagcag ggtgtttttt tatgtttgga
    84181 aagagagctc tttttgctaa actaggtttt ttcaggtaat cttagagaga aagaggtggt
    84241 ggaaatgatc aaacagtcaa aaatatctgt gcggcactta gtagaattta ttttgcgacg
    84301 tggaagtatc gacaatcgta aaaaaagtaa ccatactgca ttagaaggag cgagaatcca
    84361 ccgcaagctc caaaaagatg cgggagaaaa ctatgaaaaa gaagtctttt taaaaacaac
    84421 agttcaatta gatgaatatt acctgatcgt tgaaggccgt gcagacggta ttttcaaaag
    84481 agacggtatt tattatatag atgaaatcaa aacctccgaa ccacgatttg aagatttaga
    84541 accagaacaa gtggaacttt tctttcatca agcaagggtg tatgcctata tctatagtca
    84601 agaacatgat ttacaagaaa taaatctgca attgacttac ttccagacgg cagaagaagt
    84661 gatcacgaga aaggttgaac atcagacaag agagcagtta gaaacttttt ttaaaaagct
    84721 gactgaagat tataaagaat ggcttgtttt tcaagaaaac tggcgcactg tacgcaatgc
    84781 ctctttgatg gctttgaaat tcccccatga tgagtatagg aaaggtcagc gtgaactagc
    84841 ggtagctgct tataaaacga tccgtacgaa acagaaattg tttgtagaag cacctaccgg
    84901 aacaggaaaa acaatctcta cgttattccc cgctttgaaa gctgtagggg aagaagaggg
    84961 agaaaagatc ttttatctaa cggctaaaac aataactaga caagtagctg aagatgctat
    85021 gacagcatta aaagatacag gagctgaagt aaaaagtgtc actttgacgg cgaaagacaa
    85081 gatctgcttt ttagatgaga cgacctgtaa tccagatcag tgcccatatg ccaatggtta
    85141 ttacaatcgg attaatgaag gtttatggga tcttttgaat catgagaatc agatcactcg
    85201 tgaagtcatc gaaacttatg caagaaagca tacactttgt cctttcgaac tatcattaga
    85261 tgtcagtatc tggtgtgacg taatcattgg ggattacaat tatttatttg atccaactgt
    85321 ttatttaaga cgtttttttg aagatgaaaa aaacgaggac tatctgtttt tgattgacga
    85381 agcacataat ttggtgaatc gttcccgaga gatgtattcg gcagaactat cttatgaaaa
    85441 aacgaaacga agtaaggaag ctataccaaa ggaattcaaa aaacttcatc gccgtttcaa
    85501 caaactatta aaagaatttg attcgatccg agaaatagca aaagaagatc attgggatta
    85561 tcatcatcaa aaagcaccgg ctgaatcttt agtaaaggca ggttatcaat taagcgaaaa
    85621 aattaaagaa tggctggcag aatttcctga gcacccatca caagaacaat tgcttcctta
    85681 ttattttgat ttgcttcatt ttttgaaggt cagtgaattt tatgatgatc actacgaaac
    85741 aacagtcgaa aaaacgtatc gcgatctgat agtaaaagag ttttgtattg atccaagctt
    85801 gtttcttgag cagtcgttgg ataaaggaaa aagcagtatt cttttttctg ctagtttttc
    85861 accactctct tattatcagg aaacactggg gggacaaaaa agtctggctt acaaactgcc
    85921 gagtcctttc ccagaaggaa accagcaagt tttcatcgca aattacctag agacgactta
    85981 tcgaaaaagg gaacacagtc tggcaaaatt agtagagacg attcatgctt ttgctgatgg
    86041 aaaggtcggg aattatttcg ttttctttcc ttcttatcaa tatttagatc ttgcggtgga
    86101 agcattcaga cagcaatatc ccgacagcaa tgtgctaatc caagaaacgg acatgaatga
    86161 ggaagaacgc gaacgatttt taacaaaatt tcaaacaaat cccgctgaaa cattgattgg
    86221 attttgcgta cttggcggga ttttttcaga aggaatcgat ttgagagggg accgattgat
    86281 cggcagtatg atcgtaggtg taggtttgcc gcagatgaat catgagcagg aactgatcaa
    86341 atcatattat gatgagaagg aacaccttgg atttgcttac gcttatcagc ttcctggaat
    86401 gaacaaagtc ttgcaagctg gtggtcgagt gattcgtggc atggcggatc aaggaatcgt
    86461 tgtattggca gatcaacgat tttctagttt ttcttatcga cgtttattcc cacaacattg
    86521 gcaaacagca agagaagtac gaagtgttgg ggaattggaa gaaggaatac agcgtttttg
    86581 gttatcaaaa gaagcagtaa atcaaaaaaa cgaggaatga cagacgtcag cctcgttttt
    86641 tgattaacga tagttagtga attgcaactc gattggtaag tcaagtttac gtaataaagc
    86701 aatcacagct tgtagatcat cacggttctt acctgtcact ctaatctgat cttcttggat
    86761 ttgtgctttt actttcagtt tttcattttt gatagctgta gtgattttct tcgcgttttc
    86821 acgatcgatt ccgttgacca aatcggcagt ttgtcgagct ttgccaccta gagcgtgttc
    86881 tgattcggaa aaatggatat ttttgattgg cacatttctt ttgatcagct taccaaataa
    86941 tacatctttg atctgttcga ttttgaaatc atcatcgctc aatacaacta gattgctgtt
    87001 ctctaatttg atttctactg tagaatcctt gaagtcaaag cgattggaca attcttttgt
    87061 tgtttgctga atcgcatttt ttacttcttc tgtattgact tctgatacaa tgtcgaagct
    87121 agcatctttt gccataggaa ccctcctgat atacatataa atatttacca tacatctatc
    87181 ttatcatagg attagggcag attcttacct gtttgctaaa attcttctca tttgagttcg
    87241 aagtatttta ttttaataga taaactgtta ttcttacatt tggaatacca aagtagggga
    87301 gaggtgcttg tgagtaaaat tatgactgcg tatcataaaa atgaaagatt aaagaaaata
    87361 gtggttattt tgataaccgg attgaccgct gcggtcgctt taaattattt tttgattcca
    87421 gccaatgtct tttctgcagg gatgaatggg atcgctcaaa tcatttcctc gcttttatat
    87481 gaatggtttc atatcaagat agacacagga acatttattt ttcttttgaa tatccctgtg
    87541 tttgtattag ggtttctcaa agtaggaaaa cgagcaacga tccttagttt tgtgaatgtt
    87601 gtatgtgtat cggtgatgac gatgctgctt ccagtcggac agatcactga taatattttg
    87661 atgaatgccc tagtaggcgg tgttttatta ggtcttggcg taggattatc tttaaaaatg
    87721 ggctttacaa ctggtgggat ggatatcatc tctcttgtac tttcacaaac aactggaaaa
    87781 acagtcggaa actacatgct gattctaaat ggtatcattg tagtcatcgc aggcttcttc
    87841 tttaactggg aaagtgcctt gtatacgatt atttccattt atgcaatgac tcaagtaatt
    87901 gatgccatcc acacgagtca tcaaaaagta acagcaatga tcgttaccgt caagccagaa
    87961 gaggtaacag aagaactagc aaaacggatg gtacgtggaa tgacattact gccgtctgtc
    88021 ggtggctatt caaaaaaaca agggaacatg atcatgatgg tcatcacccg ctacgaaatg
    88081 tatgatcttg atcagatcgt tcatgaaatc gacgacgatg catttatcaa tattttacca
    88141 actcattcag tatttggccg gtttgcaaat gaaaacgaac aaaaaatgta tcgaacaact
    88201 ggcgtattgc cagaaataaa aaatcgttca caaaaaaaat gaggaatcag gtttatttta
    88261 gaataaattt aatctattac atctaataag aacattttta taaatttaaa cgagaatctt
    88321 acttctaaat tctcatttac aagcagctaa aaaaagagta tgataaataa aaatcgtgtt
    88381 aaggagtgtc gtacgatgag cgaagcaaac caagaacggt ctggacaaga aatagaacta
    88441 atcaaagaac gtattcttgc tgccttggaa atggtgattg atcctgaatt aggaatcgac
    88501 atcgtcaatt taggcttgat ttatgatata gaattcaatc ctgaaaatgg agaaacagtc
    88561 attaagatga ctctaacaac tatgggctgt ccattagcag atattttaac agaatctatc
    88621 catgacgcat taaaagaagt gccagaagta acgaaagcag aagtcaaact agtctggtat
    88681 ccagcatgga cgacagataa gatgagccgt tatgcacgga ttgcgttggg gatacgatag
    88741 aaatcttggc tgactagcta tgagaagcaa ataggaaaaa caaaaaagcc ttttatcctt
    88801 tctagaagaa aagagataaa aggtttcttt gtttataaaa ttttgtctgc tatattataa
    88861 gttaattaaa taaatgtgtt ctattgataa aggacattca aatccctttc cttttggaat
    88921 ccttcttttt tacatcagtt tgattttcgt atagtattct ttctcatctt cacgataaat
    88981 cgcagcccca tttttttgtt gtgctttaag actgccaaga ttttttttat ttacagacaa
    89041 aagtgcctca tcaatgccga ttttttttgc ctcttgtagt actaatgcta atccttgtgt
    89101 ggcatatcct tttttacgat aattagggga gatgccgtaa ccaatatggc cagcgccgtt
    89161 tcttaatgtt tcgttcagtt tatggcgcaa attaaaaatt cctacatact catgttcatc
    89221 actttctaaa ataaagacgg ttgcgggaac gtaactctca ggaagatcga ttcctaaaga
    89281 cgttttttcg cattttttta cataatctaa aaattcagca aatgtatagc cataagcatt
    89341 gttgataaat ccactctcat ttggtccaaa gctagtttgt agctgataag ctttctttaa
    89401 atctgcttcc catagtttga tcagtttcat cgtattcacc tctttaagta accttattca
    89461 tttgttttct actatagcac tattgttgta aatagccatg cctattttta tttattgtgt
    89521 catatcgtat taagaatcat cgaacaatac aaatatgaat tacaataaaa aaattatttg
    89581 aagttcgttc attcgttact tatgatctct agaagaaaga aaacgtgaat tacttcagcg
    89641 tctagaattc cagaaggata gtaatcaaca gaagaaataa tcaatatcca aatgaaagaa
    89701 gatagctgaa tcgagaaaaa gaggaaaaaa gaaatgaaga aaaaaataaa atagttacta
    89761 atcccagagt cgttcgttta acattgaaat cgatcatatg gataaaacag attttttcac
    89821 caaccctcaa tagatgatgg agttgctcgg atgaattatt tgtgtagatg gcataaggga
    89881 gggcgtacag aaatgaaaaa gaacaaaaat atgttcttga caaaaaacac atgtaatcct
    89941 aaactaaaag atgtgatgcg gctatggcgg aattggcaga cgcgctagct tcaggcgcta
    90001 gtgagggtga cctcgtggaa gttcgagtct tcttagccgc ataatttgtt tttttataaa
    90061 gagaaggtac acctggagcg atgagaaaga aaataacata ttatctaaaa gaatatagga
    90121 aaaattttaa acaacggaac cagattcaaa taaatcaaaa aaaatttgtg tgaaggtggg
    90181 acagtttaaa acctaataga ttgattcaaa tagtagattt atagattctg atacaagaaa
    90241 tactggcaaa cgatagttaa ggaataaaga ctaaacttaa actcaaaaag aggtcatgcg
    90301 aaagaataaa tcgcatgacc tcttactata ttttgaatgt gtttaaacgt tcaaataatg
    90361 aatcttagta ccaaccgttt gcttcccaga atgctttcgc cgcttcccaa gaaccataac
    90421 gtgaagtaac atattgttct gctactcttt cttggtttgc agcagagtag tcaccattta
    90481 agtaagaaga atctaattgg taacggccga tgtaacgtcc gttcgttgct gtgtaagaac
    90541 cgcttgattc tttttgtgcg atccattctt ttgcagagct tgtacttgct ggagtagcag
    90601 cagtttctgt tacagcagga gcaggttgtg tttcagcaac aggcgctgct tgtgtttccg
    90661 tttgaaccgt ttcttgtaca acaggttgtt cagcttgaac aggttcagct tggactggtg
    90721 cttcttgaac ggctgcttga ggttcagcag ctgcttgtgc agagccttct gttgggattg
    90781 ttaattgttg tcctgagtag atcaggttaa tatcagaaat tgaatttgat tctgcaatgg
    90841 cattgatcaa ggagttatca ccaacgtatt tttgagaaat cgttgataga gtatcacctg
    90901 attgaacggt ataagcttcg tccgcatgag cagtcgttcc catgaagaat gcagcgccgg
    90961 cagccaaagt tgttccaaaa agtaaagttt taagtgatgt catgaaaaat ctcctttatt
    91021 cgttaaaaag ttttatttgt tgtgttcaac gaggaatact ttaacacgtg aaaatatttc
    91081 ataggtaaaa gaagcatgac aatttatgac aaatccacgt tttttgtaac agaatgatgt
    91141 tcgctcgatg tgaaaaatga tgaggaattt cacataatgc agaaataatg ggattagaac
    91201 aggtgttctg atgagaaaag aaatgtataa ataacttgaa agaaattgct tttgttcatc
    91261 attttattta catattgcgt atattttttg tatttttgct tgagatgtta caataaaaga
    91321 aaaaggaggc ggttccaatg agtaaaagat accagaacat catggtagca gttgacggat
    91381 caagacaatc gatcaaagcg ttcgctgaag cccttgactt agcaaaggac aatgaagccc
    91441 acttatttat cgtgtcaatc atcaacaaag ttgagctgac ccatagtgcc tatgcctttt
    91501 caaaaatcta tgcagatgaa aaacaaagaa cagaagtagc catgctgaaa aaaatcaatg
    91561 atgccaaaga gtacggcatt gctgagatcc acgcaatagt tgaaactgga gatccaagaa
    91621 atttgattgc caatgtcatc cctggacaag aaaatattga tttgatcgtt atgggagcga
    91681 caggaaaagg tgctatacaa caagcattag ttggatcgac cgcttcttat gtcgtatcac
    91741 atgccccttg cagtgtgttg gtcgtgaagt aatgagataa gggaggaata gaaaatggtt
    91801 cgtcctcaag aagtccgtgc gccaaaagaa aaaatagaaa ttttagcaat tattgaagac
    91861 ggcacacaaa caaagaaggg atactcgatc gctttagtaa agtggaaagg aaaaaaaggt
    91921 gttgctctga gatgggatgg agataaccaa caagataaag gattccctgt cacagctaac
    91981 ggttatcatc cagcgtggtt tgttctgcct gataaattta tggaattata cagctatgat
    92041 tatgcaagag ccgcagcatc aatcaaagca ttagataaat taacagaaga gcagaatgaa
    92101 atggaggaaa aataaaaaag acgaaccaat cagcctttag aaaactgatt agttcgagga
    92161 gtaaaaatga aaaaaggtta tttgggatga aactagaata atgcgtataa cttaaataaa
    92221 acttaaagca ataaaatggc aagagggtga ggcaaatgga agcaggaaaa gtattacagg
    92281 aagtaaaagc actatgtgca gataaaaaat atgaagaagc gaaaagcctg atcgaaaaga
    92341 acaaagaaaa tttggaagaa aagtacccga tcgcacaaga atttatagaa ttaaaacaag
    92401 gaacgatcct tcaccgattc aaacattttt ttggtataac agaatagaaa aaacgattaa
    92461 agatcggcag aaatttgctg catctttaat cgttttcttt ttaaacatgc gagggattca
    92521 attctgattc ttatataaaa aatagatcca aataataaga aaaattactg aaagcgtcaa
    92581 ttcgatgatg tgtgttatta atacagacgt tgtttcccaa tgcctaaaag aaaaaatttg
    92641 ataagtaaaa tatacagcag gtaaagaggc cagtaaaact gaaaacttct tttttgtcca
    92701 ttttatgtaa tagaaaagaa tgcttatcat aataaaaaaa ggaatataaa aaacaaattg
    92761 accgatcgcg atcatactat tgcctccgat aaataaagtc catgatacaa aataacactt
    92821 tgtgcgaaat ggcgcaagca gttttgtgga tttatccggt aaaatctgta tcgattttga
    92881 aattagagga gaaacttgct ataatcaaag tgaaagaagg agtgggattt tcatggatca
    92941 tgtagtgtta gaaatcgatt tgcatttgat caataatatt cgggtgattt actatgttgt
    93001 aagtaacagt gtcgaacaac gtgtactgac gaataaaata aatggtattt tagcaaagaa
    93061 agacgttcac cgattcaata atggtgaagg aagttattat agtatcccag tagaaaaaat
    93121 tatttatacg acagtcaaag tcagagaaga tctagatacc aaaaaagcat atgaacctat
    93181 ttttacaact tattgattga cagcagatgg aggaaaaaaa tgaatccata tgaacaactt
    93241 attcaagatt tgatcgatgg aaaaatcgaa aagattgatg taaaaagaga agaattaatg
    93301 gcttttcgag aagcgtggct gaagttggag aatcgtaaat atgtggtggg aaaagcctca
    93361 ctgaacggca atgtgactta tcattacgat ccgacacgtt tattttagta tgaagtattc
    93421 agaaaagaac caaaggagga cgatgcagca gcattgtcct cctttgattt tacaaaagtg
    93481 aaagttttac ttatttgaat agatttttaa atttgttttt gacactgtcg atatttacat
    93541 cttttaaaag attttgggct ttctctttat aaggtcctaa ttgttcttta tgttcttcga
    93601 taaatcgttt tgcgccatcg aaattgccgt tcttaatcat ttccttgact ttttgaaata
    93661 attcttcttg attcattttg aacacatcct ttgctatcaa catgattttt tacatggaca
    93721 aaacgagaaa aactgattta tccacacgtc aataatatca aataacgatc atttttacta
    93781 aaaaaacact cgattctcgc ttctaaagta ggagaaaaat ctccaacttg ggacggatgg
    93841 aatttcttta actgacccat atactgaata tataacaagg aggtagaaag atgaaagtga
    93901 ttaaatattt gattggactg gcggcgatta gtggtatttt gctatttgga ctgaaatatt
    93961 atactgaagg aagttatgga gaaatccctg gtatacttga tcagctaaat ccattagttg
    94021 aaaaaggaga ggtctatgta aagacacaaa aaccagagga agtaaatgaa tatggtacag
    94081 caaggtatgt gcagaaagct gctgatgcca atgggaaaga acgaacggtt gaatttaatg
    94141 gtctttctgt gttaaaagaa aatcattatt tgaaaattag caataaagga gcacacatag
    94201 aaacgtatga ggaagttcct agagaaaaag ttccggagaa agcattagca attattgggt
    94261 aaatcagttt ttgtattaag aatacgcccg attttattat tcataattta attatgtaaa
    94321 ctaaatacaa gtagtaaaaa taatacaata atccccctgc aaaaagattg ttcttttaca
    94381 gggggttcat tttttcagca agcacatcaa attgggatgg cagggttcga acctacaatt
    94441 gcttgattca gagtcaagtg ccttaccagt ttggctacat cccatttatt caacaaaata
    94501 atcatagcac tttcctaaaa aaacgcaagt tatttttctt gatcggatag ttgttgcttt
    94561 actcgtaaaa ggcggcgtac tagtttcttt tctaatccag caggaagggc aatcagttct
    94621 gctactgaca agacggtgtc caataactga tattctttga caggttcatt cataatatga
    94681 tagatgtttg ctaaacgttc aatatattca aagcgagtat actctgttcg agcaattaga
    94741 aatttcaata aatcggtggc tttctcgtac tcttgatctg cgtaataaac aagagattga
    94801 cgatacaatt tgatttccag ttcattgagg gtagcaggtc tgcgacgctc gttccactca
    94861 ttaatagaga ctttaccttg aacatttccc ttgcagtcac ggacaaaaat aatcggaatt
    94921 tcatttggat ccattttttt atgtgtgaat ttttccatta tctacgctcc cttcaaaggt
    94981 ttggtatctt gagtataagg gatttttgtt tgaattacta gcttttctcc aaagttagca
    95041 tctgtccacc cattgcagtg aaaatcgccg aaaaatcgtt gatcggtact gctcgatttt
    95101 ttacaccata gggatcgttg acataaatat tttctttgtc atatccagtg actacacaag
    95161 catgaacaag aggagtgact cttacttctc cattatttgt ggtccaagtc ataaaatcag
    95221 tttcatctgg gacttcaaaa ttgatagtca cagaagtcca gacaggattt cctttagata
    95281 gtgctttttt gatatcatcg agttgagcat cggtttttgg aaaagtgtga taatccgttt
    95341 ggacgatttg ctgagcaagg gaggcaactg ggggaacata gacgaccata gcccagtctc
    95401 cgccactgat atcaccaaca aatccttcat taggatcgcc atgagtccca tctgcattga
    95461 aaacagggac gtaatccaat tgctcagcta actggttttt agttgtttca taaccataaa
    95521 aagataaaag catagaaagc gaagtgactt cacagccatt ttctaaagaa ggagaatcaa
    95581 actggctctc taatggaaca tctagtaaaa cttctgcttt ctcttttgtc tttttcgttt
    95641 tttgtgttga acttttttgt gcagtgttca ttgtatgttc tggagaatgg atatgtaggt
    95701 aataacttgt accgcttaat aaaagagcag ctgtgccccc tagaaacaat agttttttga
    95761 acgttttttt cttcatttga aatctccctt ttcagctgtt tatctttcct attataaatg
    95821 tatttttatt ggaaatggaa gtattatatt ttaatatgta ggaaataatt agtttttaag
    95881 gaatatgttt taattttttg aaaaaaattc ttctaaatac aacagctgtt ttaattgtga
    95941 aaacgaaaac agtacgctat aatgcctgta aggttgattt ttaactgtaa ataaaaatca
    96001 atgagttaaa tctccaaaga aatagcagtg gtaatgtgga gaaaagttcc agcagtttag
    96061 gaggattttg atgacggaag aaatgattaa tttaggagaa caatatgcat gcaaaccaat
    96121 tggttttaca aaaacggtca ttggtgaagt tgtatcaaaa atgacaaact gcgccgtggt
    96181 caaagttgcc caatgtgctg cagaggacca agaattatta gatgaaaaag caagcatggt
    96241 tgttgcaaaa tatgatacat ttgaataaag aaaacaattg gacgtgcggc gtgctgcaag
    96301 tccaatttct ttgagaaggt aaatcagtat tcttttccta ttttctggag aagaaaaagc
    96361 gaggcgagtt gtcatggtaa cattctttac ggttctattg tttttattcg ttgttgtgat
    96421 gtttttattt ctttggctgg ttcgaaaaga aattatttat cggactgtgc gaaatcgatg
    96481 ggtctacttg gtgataccct tcttagtgtc actagtcatt tggtatacac tcatcagtca
    96541 tcctacagca gatgaattgg caaaagggat cttgtcagca atgattttta ttagtttttt
    96601 gttggacagt agaggaatca cagaagaagg acttgttttg aatagctttg acaaaaaagg
    96661 tgttcctttt tctgagatca ataaaattgt attatatcag ccaaaaggtt ctaaaatcgt
    96721 aaaaatgaat tttttccgaa acggatggcg aggaccgatg ctgaaatttt ctgcatcatt
    96781 agaagaatta gttccatttt tgtcccaacg cttaaacgat gaggcagaga ttgatattat
    96841 gattgatcca gaataaaaac agaggttgcg acaagatgtt tgtcacaacc tctgtttttt
    96901 atttcaaata aaattatcca aatacgcgga agcgatcggc atcgttcatg tattcttttt
    96961 ccccagccgg tgtttctggt gaaccgaata ctaattgcga acgtagtttc cagtttgaag
    97021 ggatattcca ttcttttgca actgcttcgt caataactgg gttgtaatgt tgcaagtttg
    97081 cgcccaatcc tttatcaact aatgctaccc aagtattagc tgttgcgatt ccgtttgatt
    97141 gttctgacca atctgggaag ttgtctgcat ataattcaaa ttgttcttgt agacctttta
    97201 ccacgtcagt atctttgaag aataatactg taccataacc atttttgaaa ccagctaatt
    97261 tgttttgtgt atttgggaaa gcttctgctg gagtcaatgg gcgaagtgct tcttcagtga
    97321 tttcccaaag tttttcatgt gcatctccga aaaggataac tgcgcgtgtt gattgagcat
    97381 tgaaagcagt tgggctttct ttaattgctt ctttgatcaa agttgttaat tcttcattag
    97441 aaagtgaaac attacgtcct agatgataga ttgaacggcg gtttttcaaa gtgtcagtaa
    97501 aagttgtcat aataaaattt ctcctttgat ttgcgttttg cattttttta attgattacg
    97561 aaatgaagta tagcacctta caaaaagtaa gtaaacagat atgctcacaa aaaataagcg
    97621 aagttcaaaa aacaatttta ataagaaaaa tcgttatgta aggattttct tagttatcgc
    97681 tttcattgtt gtgttttagg aatttttgct tatttgaaaa aaacagctga tatataatta
    97741 ttaaatctct atcttctttt ttttatgata ttgccattaa aaattacttg cttttataga
    97801 aaattagttt atatttctta aataagtttt ttagttaaat ttttcggtaa agatgtataa
    97861 tattttctga aaatttaaag aattggggta tagattatgg aaaaacagca agacaagggc
    97921 ttcttcgggc agccgaaggg attgtcaact ttgttcttca ctgagatgtg ggaacgattt
    97981 agttattacg gtatgcgtgc attacttatc tattatatgt acgatacagt tgccaacggg
    98041 ggacttggat taccacgagc aacagcatta gctatcatgt cgatctacgg atctttgatc
    98101 tacatgtcta gtatcgtcgg cggatgggta tctgaccgag tgttaggagc aaaacgcact
    98161 gtattcttcg gtggagtttt cattatgctt ggccacatcg tcttggcttt accatttggt
    98221 gtaagtacat tgtttgtttc gatggcattg attattatcg gaaccgcctt tttgaaacca
    98281 aatgtttctg gcatggtcgg acatctttat tcaaagactg acttgcgaag agatgcagga
    98341 ttttcgattt tttacatggg tgtcaactta ggggcattat tagcaccact aatcgttggt
    98401 acaatcggtc aagaatataa ctatcattta gggttctctt tagctgctat tgggatgttc
    98461 tttggattat tacaatacat catccaagga cgcaagacat tagacggagt gggtacaaca
    98521 ccgccgaatc ctttgacaac tgaagaacgt aaaggattca tccgtaactt gatcatcgca
    98581 cttgttgtta tcgctgcagt attcggcggg gcacaactaa ctggtcatct gacaattgac
    98641 ttttttgtca atacaatcag tgtattgggg attatcttac cgttgtatta ctttatcaaa
    98701 atgctgactt caaaagatgt aactgctgaa gaaaaaccaa gagtatgggc ttatatccca
    98761 ttattccttg cagcaatcat tttctggtca ttacaagaac aaggttcatc tatcttagct
    98821 ttatttgcta gtgaacgtac acaatctacg ctatttggtg taacgatcca agcaagctgg
    98881 tatcaatcat tgaatccaat tttcatcttt attctgacac cagtattcgt aacgatgtgg
    98941 acgaaacttg gtgaacgtca accatctaca gtagtgaaat tctctcttgg acttttattt
    99001 gcaggattat cgtacttgct attgatgttg ccgggtatgc tttatggtac aagtggaaaa
    99061 gtaagtccat tgtggttgtt gggaagtttc ttcatcgtgg ttattgctga attgtgtctt
    99121 tcaccagttg gtttgtctgt gacaacaaaa ttagcaccac gagcatttga atcacaaaca
    99181 atcgctattt ggttcttagc tgatgcttct tcacaagcaa tcaatgcaca aattgcacgc
    99241 ttctacacac cgggaacaga atctgcttac ttcggtatta tcggtgcagt agcaatcgtc
    99301 ggtggtatct tgctatttac tgtgaaagaa ccaatcaaaa aactaatggg ctctattcat
    99361 taatcaatga acataaaaac aggaattgct tatttgcagc agttcct
//
LOCUS       DARPZF010000005        92225 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.005, whole genome shotgun sequence.
ACCESSION   DARPZF010000005 DARPZF010000000
VERSION     DARPZF010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 92225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..92225
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.005"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(554..2167)
                     /locus_tag="SLE65_000506"
     CDS             complement(554..2167)
                     /locus_tag="SLE65_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEI8447827.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2307..3215)
                     /locus_tag="SLE65_000507"
     CDS             complement(2307..3215)
                     /locus_tag="SLE65_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8447828.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3398..4522
                     /locus_tag="SLE65_000508"
     CDS             3398..4522
                     /locus_tag="SLE65_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEI8447829.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4749..5666
                     /locus_tag="SLE65_000509"
     CDS             4749..5666
                     /locus_tag="SLE65_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8447830.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5659..6492
                     /locus_tag="SLE65_000510"
     CDS             5659..6492
                     /locus_tag="SLE65_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEI8447831.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6575..7693
                     /locus_tag="SLE65_000511"
     CDS             6575..7693
                     /locus_tag="SLE65_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEI8447832.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7687..9585
                     /locus_tag="SLE65_000512"
     CDS             7687..9585
                     /locus_tag="SLE65_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HEI8447833.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            9579..10802
                     /locus_tag="SLE65_000513"
     CDS             9579..10802
                     /locus_tag="SLE65_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEI8447834.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10888..12822)
                     /locus_tag="SLE65_000514"
     CDS             complement(10888..12822)
                     /locus_tag="SLE65_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEI8447835.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13048..13704
                     /locus_tag="SLE65_000515"
     CDS             13048..13704
                     /locus_tag="SLE65_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEI8447836.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13778..14131)
                     /locus_tag="SLE65_000516"
     CDS             complement(13778..14131)
                     /locus_tag="SLE65_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEI8447837.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            14323..15252
                     /locus_tag="SLE65_000517"
     CDS             14323..15252
                     /locus_tag="SLE65_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEI8447838.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15263..16099
                     /locus_tag="SLE65_000518"
     CDS             15263..16099
                     /locus_tag="SLE65_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEI8447839.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16347..17123
                     /locus_tag="SLE65_000519"
     CDS             16347..17123
                     /locus_tag="SLE65_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8447840.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17299..18042
                     /locus_tag="SLE65_000520"
     CDS             17299..18042
                     /locus_tag="SLE65_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8447841.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18035..19615
                     /locus_tag="SLE65_000521"
     CDS             18035..19615
                     /locus_tag="SLE65_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEI8447842.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19866..20345)
                     /locus_tag="SLE65_000522"
     CDS             complement(19866..20345)
                     /locus_tag="SLE65_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEI8447843.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20361..21113)
                     /locus_tag="SLE65_000523"
     CDS             complement(20361..21113)
                     /locus_tag="SLE65_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEI8447844.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21230..21300
                     /locus_tag="SLE65_000524"
     tRNA            21230..21300
                     /locus_tag="SLE65_000524"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21262..21264,aa:Gly,seq:ccc)
     gene            21661..22386
                     /locus_tag="SLE65_000525"
     CDS             21661..22386
                     /locus_tag="SLE65_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEI8447845.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22641..22907
                     /locus_tag="SLE65_000526"
     CDS             22641..22907
                     /locus_tag="SLE65_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEI8447846.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22904..23335
                     /gene="ruvX"
                     /locus_tag="SLE65_000527"
     CDS             22904..23335
                     /gene="ruvX"
                     /locus_tag="SLE65_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEI8447847.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23360..23665
                     /locus_tag="SLE65_000528"
     CDS             23360..23665
                     /locus_tag="SLE65_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEI8447848.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(23746..24891)
                     /locus_tag="SLE65_000529"
     CDS             complement(23746..24891)
                     /locus_tag="SLE65_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEI8447849.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(24952..25599)
                     /locus_tag="SLE65_000530"
     CDS             complement(24952..25599)
                     /locus_tag="SLE65_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8447850.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            25793..26086
                     /locus_tag="SLE65_000531"
     CDS             25793..26086
                     /locus_tag="SLE65_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447851.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            26130..26441
                     /locus_tag="SLE65_000532"
     CDS             26130..26441
                     /locus_tag="SLE65_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447852.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            26438..27062
                     /locus_tag="SLE65_000533"
                     /pseudo
     CDS             26438..27062
                     /locus_tag="SLE65_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            27203..27361
                     /locus_tag="SLE65_000534"
     CDS             27203..27361
                     /locus_tag="SLE65_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447853.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            27362..27724
                     /locus_tag="SLE65_000535"
     CDS             27362..27724
                     /locus_tag="SLE65_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447854.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            27761..28609
                     /locus_tag="SLE65_000536"
     CDS             27761..28609
                     /locus_tag="SLE65_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEI8447855.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            28599..30074
                     /locus_tag="SLE65_000537"
     CDS             28599..30074
                     /locus_tag="SLE65_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEI8447856.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            30340..30747
                     /locus_tag="SLE65_000538"
     CDS             30340..30747
                     /locus_tag="SLE65_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HEI8447857.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            30750..30965
                     /locus_tag="SLE65_000539"
     CDS             30750..30965
                     /locus_tag="SLE65_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447858.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            30969..31349
                     /locus_tag="SLE65_000540"
     CDS             30969..31349
                     /locus_tag="SLE65_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEI8447859.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            31483..31638
                     /locus_tag="SLE65_000541"
     CDS             31483..31638
                     /locus_tag="SLE65_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HEI8447860.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            31707..32180
                     /locus_tag="SLE65_000542"
     CDS             31707..32180
                     /locus_tag="SLE65_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HEI8447861.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            32177..33871
                     /locus_tag="SLE65_000543"
     CDS             32177..33871
                     /locus_tag="SLE65_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEI8447862.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            33837..34022
                     /locus_tag="SLE65_000544"
     CDS             33837..34022
                     /locus_tag="SLE65_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447863.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            34026..35201
                     /locus_tag="SLE65_000545"
     CDS             34026..35201
                     /locus_tag="SLE65_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEI8447864.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            35194..36717
                     /locus_tag="SLE65_000546"
     CDS             35194..36717
                     /locus_tag="SLE65_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEI8447865.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            36773..37057
                     /locus_tag="SLE65_000547"
     CDS             36773..37057
                     /locus_tag="SLE65_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HEI8447866.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            37044..37379
                     /locus_tag="SLE65_000548"
     CDS             37044..37379
                     /locus_tag="SLE65_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEI8447867.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            37674..38300
                     /locus_tag="SLE65_000549"
     CDS             37674..38300
                     /locus_tag="SLE65_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447868.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            39042..39878
                     /locus_tag="SLE65_000550"
     CDS             39042..39878
                     /locus_tag="SLE65_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEI8447869.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            39943..40377
                     /locus_tag="SLE65_000551"
     CDS             39943..40377
                     /locus_tag="SLE65_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8447870.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(40445..41767)
                     /locus_tag="SLE65_000552"
     CDS             complement(40445..41767)
                     /locus_tag="SLE65_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HEI8447871.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(41921..43561)
                     /locus_tag="SLE65_000553"
     CDS             complement(41921..43561)
                     /locus_tag="SLE65_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HEI8447872.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43891..44361
                     /locus_tag="SLE65_000554"
     CDS             43891..44361
                     /locus_tag="SLE65_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HEI8447873.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            44990..46093
                     /locus_tag="SLE65_000555"
     CDS             44990..46093
                     /locus_tag="SLE65_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HEI8447874.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            46377..47057
                     /locus_tag="SLE65_000556"
     CDS             46377..47057
                     /locus_tag="SLE65_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HEI8447875.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            47147..48181
                     /locus_tag="SLE65_000557"
     CDS             47147..48181
                     /locus_tag="SLE65_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HEI8447876.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            48195..48530
                     /locus_tag="SLE65_000558"
     CDS             48195..48530
                     /locus_tag="SLE65_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447877.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            48514..50976
                     /locus_tag="SLE65_000559"
     CDS             48514..50976
                     /locus_tag="SLE65_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447878.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGIPLQFDVTANVAKMTENGDKYDTSPN
                     KILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGGNLNPGA
                     YAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLTMGLTEG
                     RFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQGGLLSP
                     VALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIHYRLYSK
                     GTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTNMYPSFA
                     YKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQENVTFT
                     LTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLSKIGDTI
                     HLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTILVPKQEL
                     TLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLTSLFKND
                     QGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLLEVNSST
                     NAQPGATYQGMVTWELTAGPTS"
     gene            51032..52591
                     /locus_tag="SLE65_000560"
     CDS             51032..52591
                     /locus_tag="SLE65_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8447879.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            52588..53952
                     /locus_tag="SLE65_000561"
     CDS             52588..53952
                     /locus_tag="SLE65_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEI8447880.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            54123..55193
                     /locus_tag="SLE65_000562"
     CDS             54123..55193
                     /locus_tag="SLE65_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8447881.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            55208..55876
                     /locus_tag="SLE65_000563"
     CDS             55208..55876
                     /locus_tag="SLE65_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8447882.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            55896..56474
                     /locus_tag="SLE65_000564"
     CDS             55896..56474
                     /locus_tag="SLE65_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEI8447883.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            56877..57788
                     /locus_tag="SLE65_000565"
     CDS             56877..57788
                     /locus_tag="SLE65_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEI8447884.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(58044..58961)
                     /locus_tag="SLE65_000566"
     CDS             complement(58044..58961)
                     /locus_tag="SLE65_000566"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEI8447885.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            59163..59600
                     /gene="zapA"
                     /locus_tag="SLE65_000567"
     CDS             59163..59600
                     /gene="zapA"
                     /locus_tag="SLE65_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEI8447886.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            59658..60206
                     /locus_tag="SLE65_000568"
     CDS             59658..60206
                     /locus_tag="SLE65_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEI8447887.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            60321..62681
                     /locus_tag="SLE65_000569"
     CDS             60321..62681
                     /locus_tag="SLE65_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEI8447888.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            62768..63082
                     /gene="trxA"
                     /locus_tag="SLE65_000570"
     CDS             62768..63082
                     /gene="trxA"
                     /locus_tag="SLE65_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEI8447889.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            63264..65042
                     /gene="uvrC"
                     /locus_tag="SLE65_000571"
     CDS             63264..65042
                     /gene="uvrC"
                     /locus_tag="SLE65_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEI8447890.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            65187..66086
                     /locus_tag="SLE65_000572"
     CDS             65187..66086
                     /locus_tag="SLE65_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8447891.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            66079..67341
                     /locus_tag="SLE65_000573"
     CDS             66079..67341
                     /locus_tag="SLE65_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8447892.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            67502..69400
                     /locus_tag="SLE65_000574"
     CDS             67502..69400
                     /locus_tag="SLE65_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HEI8447893.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(69699..70418)
                     /locus_tag="SLE65_000575"
     CDS             complement(69699..70418)
                     /locus_tag="SLE65_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEI8447894.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            70755..71087
                     /locus_tag="SLE65_000576"
     CDS             70755..71087
                     /locus_tag="SLE65_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447895.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            71074..73077
                     /locus_tag="SLE65_000577"
     CDS             71074..73077
                     /locus_tag="SLE65_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEI8447896.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            73096..73566
                     /locus_tag="SLE65_000578"
     CDS             73096..73566
                     /locus_tag="SLE65_000578"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEI8447897.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            73587..74171
                     /locus_tag="SLE65_000579"
     CDS             73587..74171
                     /locus_tag="SLE65_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HEI8447898.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            74186..75172
                     /locus_tag="SLE65_000580"
     CDS             74186..75172
                     /locus_tag="SLE65_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEI8447899.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            75162..75473
                     /locus_tag="SLE65_000581"
     CDS             75162..75473
                     /locus_tag="SLE65_000581"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEI8447900.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            75495..77276
                     /locus_tag="SLE65_000582"
     CDS             75495..77276
                     /locus_tag="SLE65_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEI8447901.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            77269..78645
                     /locus_tag="SLE65_000583"
     CDS             77269..78645
                     /locus_tag="SLE65_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEI8447902.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            78652..79287
                     /locus_tag="SLE65_000584"
     CDS             78652..79287
                     /locus_tag="SLE65_000584"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEI8447903.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            79317..80672
                     /locus_tag="SLE65_000585"
     CDS             79317..80672
                     /locus_tag="SLE65_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEI8447904.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKFAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKITIHSKIALTVTGTLLLGGFVVFFFTERNGETLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(80864..82258)
                     /locus_tag="SLE65_000586"
     CDS             complement(80864..82258)
                     /locus_tag="SLE65_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEI8447905.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQKLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQNKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            82350..83321
                     /locus_tag="SLE65_000587"
     CDS             82350..83321
                     /locus_tag="SLE65_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HEI8447906.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKDKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSATLTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            83318..84099
                     /locus_tag="SLE65_000588"
                     /pseudo
     CDS             83318..84099
                     /locus_tag="SLE65_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
     gene            complement(84268..84639)
                     /locus_tag="SLE65_000589"
     CDS             complement(84268..84639)
                     /locus_tag="SLE65_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEI8447907.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TTPSYYFVIDPDGYKIEVIRG"
     gene            84773..85216
                     /locus_tag="SLE65_000590"
     CDS             84773..85216
                     /locus_tag="SLE65_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEI8447908.1"
                     /translation="MDKPIFGEKKQSANYQTRYAAYIVIERDKRIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(85259..86068)
                     /gene="yidA"
                     /locus_tag="SLE65_000591"
     CDS             complement(85259..86068)
                     /gene="yidA"
                     /locus_tag="SLE65_000591"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEI8447909.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(86087..87454)
                     /locus_tag="SLE65_000592"
     CDS             complement(86087..87454)
                     /locus_tag="SLE65_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEI8447910.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHKVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(87438..88268)
                     /locus_tag="SLE65_000593"
     CDS             complement(87438..88268)
                     /locus_tag="SLE65_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HEI8447911.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            88431..88868
                     /locus_tag="SLE65_000594"
     CDS             88431..88868
                     /locus_tag="SLE65_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEI8447912.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            88944..89564
                     /locus_tag="SLE65_000595"
     CDS             88944..89564
                     /locus_tag="SLE65_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEI8447913.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     EKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            89753..90259
                     /locus_tag="SLE65_000596"
     CDS             89753..90259
                     /locus_tag="SLE65_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HEI8447914.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            90276..91175
                     /locus_tag="SLE65_000597"
     CDS             90276..91175
                     /locus_tag="SLE65_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HEI8447915.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKARR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            91262..92147
                     /locus_tag="SLE65_000598"
                     /pseudo
     CDS             91262..92147
                     /locus_tag="SLE65_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
BASE COUNT        30494 a        15647 c        18972 g        27112 t
ORIGIN      
        1 tgttaaataa ataggaacaa aaaaattaaa ttatttaata cacacattag ggatcattca
       61 ttgaaggatt agaagacaac gaggatggcg aaaaatatga ttacaataga aaagtcgttc
      121 taaaccaatc agttcctagt atcacacaac gcaagccagt cgatttggtg agattagagg
      181 agtgaaagca aactttatta tataagaaaa aatattcgaa agggatgcta gtttaggtac
      241 tagtgctgat agattaatat gatgcctcgt aatattaggc gtagttactc tagagacatc
      301 actatggact atgatttgtc tcagagtcac aacatgtttt tttatgaaaa gaaacagcta
      361 aaataattaa attgcgcaat gtttaaactt tcttaaacta taacctaata aatgtgaaga
      421 aataatgcac aatttcttca catttatctt ctattctata tacataccaa ccaacaaccc
      481 tatatacttt ttcattttta ctcctcaagt aaaaataact cctagaccgc ggctacccac
      541 cgcggtcgtt tttttattct tcaatcaaaa tcgctttgat acccaaacct gccaagattc
      601 gggcagaagt ataagtattc aatcctcttc tgaaagtaat gtaaactttt ttatcttttg
      661 ggatttcatt gattcgatct cgtaactcat tcattggaat attttttgtt gccgagatac
      721 tgccagaagg tgctttatta ggttcacgta tatctaaaaa gaacgcttct ttcaaatcgt
      781 tttcgggtat atcacttgct ttgatcgttt ctacgatatt cgtcatttga ttgattgcga
      841 cataaccagc tatattcaac gggtcacggg tagtagaata cggtggagag taaggcaact
      901 ccaaatcagg caaatcaaag actgtcaagt ttccggtgat tgctacagaa agttctccca
      961 tccgtttatc gacacctttt tctccaaatg cttgtccacc taaaatacga ccgctatctg
     1021 catcaaaaat cagctttaga tttaatcttg tagcttctgg atagaaatag gcatggtcaa
     1081 agggagtgat aaaaacagtt ttataatttg ttatgcctga tgcttttaat tcatgttctg
     1141 tcattcccgc ataacttgct gtatgatcaa agatttttgc gacacctgca ccaatatatc
     1201 cgcgatagcg cataggcgta ccatttaaaa tatctgccag catatgtcct tgacgattgg
     1261 ccgcactgga aagcatactt tggatcggct gaccagtcac tacactagtc gtttcgataa
     1321 tatcgccaat cgcatagatg tccggcagat tggtttgtaa ctggtcatca acaatgatct
     1381 gacctgtatc tgataattgt atgccggttg ctttcaccac ttcattcttc ggagaaacac
     1441 caacagcaaa aattagcata tcagcagaaa ggacggagcc atctgataat actatttctc
     1501 gacctttatc acggatctca gtaactcttg tttctaaatg aacggctaat ccttctttca
     1561 gcaatttgtc ataaactaaa ttagcaattt ctggatcata agggaaagcg acttgtggca
     1621 attgatcgat taaagtcacg tctaagccgc gatgcttgaa attctcagct aattccagac
     1681 ccataacacc tgcaccaaga atgacgacat gttgtggatt tttttcttca aggaacgatt
     1741 tgattcgatc cgcatccgtc acactacgga ggacaaagcc gttttctgct tcaaaaactc
     1801 cgggaatatc cggataatct ggtctagcac cagaagagat gatcaactta tcgtaatctg
     1861 tttttatttc ttcatttgtg gataggtctt taactgttaa tcgcttagta gaaggatcga
     1921 ttgctgttac ttcgtgttta gtaaagacat cgatgttgtt ttttgttttc aatatttctg
     1981 gtgtacgttc gatcagcgag tcacggtcag tgatcacacc tcctaaataa taaggcaaag
     2041 cacaacttgc ataagaaata ttttctccgc gttcatagat aatgatttcg tgcgcttcat
     2101 tcaatcgacg gaaacgagtg gcaaatgaag gaccgccagc tacaccgcca atgacaacaa
     2161 ctttcataaa aacatctcct tttctacgtt gatcgtacta tgttatggta aaaaacaaca
     2221 aataattgtg ccggaaaatt attgtttatt ttgaatagac agaaaatata gagaaataat
     2281 ttgtggataa aacctaaaaa atttttctat tttaaggata gataatactt tgaaggggat
     2341 aaccctgtat attttttaaa agctgaagaa aaatgatgga tcgaatgaaa tcctaatata
     2401 tctgcaattt ctgtataggt taattcattt tctagcacga gacgttttgc tttttccatt
     2461 tttagttctt taaaatagct aataacactt tttccattca cttttctaaa atgttttttt
     2521 aagctggctg gactgataaa aaaaatttgg gctaattgtt caagcaaaaa attttctgaa
     2581 agatgttctt ctaaatatcg tatgattgga tcaactaatt catctgaata aagaatatgc
     2641 ttttttttag gaatgacttt ctcatttgaa ggtattgtca ataaagcaag ttcctgttga
     2701 taatgccttg gtaaggaaga caattgaatt ttttgcagac aataagtaac taataaggaa
     2761 agcaaatgaa tgctcatctg ttggcatagt atgaaaaaag aattgatttc ctgatcatag
     2821 gaaatagctg gcttactatg ttttagataa tcaattttga actgttcatt tttcagaaaa
     2881 gtaatgatag atgttatttc ttgatctata gaaaaagatt gtcccgtaat atgtgctaat
     2941 aattgctcat caaaataaaa ctggataatg ataaaagttt gtgtttcctt ttgagtagaa
     3001 aagatttgga cttcttgctg tttatcaatg aataaaaggg aaggattatc tagttctata
     3061 gatttatgtg caaattcagc atataaatta gcgctttcat ttattagtag tcgaaaatag
     3121 ggagcagcag ataaatgaag atgggtatct atggaatagg ttagtgtttt tttgacaaga
     3181 ttggaggatt ggttgtttgt taacaaaaga accactttcc tttctctttt tatataaaaa
     3241 gctttctatt tataattaat gactattata acaaaaatga aaagccaaaa cgacaagtaa
     3301 aatatttttt tatataaata tttgtgttac taattccgtt aatatacata agtgaaagcg
     3361 ttttatataa gaacttgaaa agaaagaagg gatagacatg aaaaaaagat acaaattggt
     3421 gatagctttg ctaaacatta ccctattatt cagcttaagt gcatgtggaa aaactaacga
     3481 agaagtaaca gcaaacatcg cagatccaat gataaaaaaa gccactacat tagaagtata
     3541 tgtcgcaaac ggcaaactga caaactatgt tgaaaatgct gcaaaaatct ataaccgcaa
     3601 aactggagca aatattgact taaaaattgt gaatgtagct tcgggaacag caacagtaca
     3661 aatgatcacc ccaaaattgg taacacacga agatatgccg gatattatct ccatggcaga
     3721 cacttcagca gcaggtgtgc tggaaaaatt tcaagatgct ttttatagtg ctgatgaata
     3781 tggattttat gacaaatatg gcgatcagtt ttatgatcaa aaattgaata ttttgcgtca
     3841 acaaacgagt aatgaaacga ttattccttg ggctagtgat tttaccccag cactttgtta
     3901 ttatcaacca aaaaaatttg ctgaaatagg tgtagatttt gaagaaatca gttcttggga
     3961 agaatatatc caggtggcaa aagcattaaa agaaaaaact ggtagttttg gaattgcctt
     4021 gccagaatct ggggaccaag aattgtttat caacatgcta gcccagcaga atcaatcttt
     4081 gcttgatgaa gaaggaaata tccgtctgaa tactaaagaa gcgaaacatg ctgcaaagtt
     4141 aatcaaagaa atgatcgact cagatattgt acatttctac ggtgcacaag atgctgagaa
     4201 agcatttcaa gaatctgcaa tgtttgttgc tggcggctgg tatgctacga atatgtcttt
     4261 gaattttcct gatgcatctg acaaatggcg catggctcca ctgattcctt tttcaaaaga
     4321 aaatccagga aaaggtgcag tatcaggagg atcaagtttt tatgtcccta aagatgccaa
     4381 aaatccacaa gtggcacaac aatttcttac atttatgctg acagatgaag aatgcttagc
     4441 caacgcactg gagctgggcg tggctacatc taactcattg gcctatcaaa cagaagcagc
     4501 tgagaaaaag tttgactact aaggaggaca aaaatactat gaactattga ataaaatcaa
     4561 tgaaaataca tcaaatactg ttttaccagc cacttattca gatgctacgt cttatttgac
     4621 taccgctgca tataactatt ggcaaacagg tgattttgaa aattcatatc taaaagaagc
     4681 agaaaatttt gctcataagt acggcgtaaa attaactggt gattaaaaaa tattaggagg
     4741 acttaacgat gatgcaatct tcgttaccaa gcaagacaat aaagaacagc aagaaaaaag
     4801 caacagatac gtctcataaa aaaagtgctt atggattggt cacacctttt gttattttct
     4861 ttattgtgac gattttgatt cccatcatta tctcgtttgc ttttagtttt atgaaaattg
     4921 gctactcatt tgaatttgtt ggatttgaca attatctagc tatcttccga gatccattgt
     4981 ttattaaatc ttacacgaat gttttgatta tcatggcagg atcaattcca ataacgatgc
     5041 tattagctat ttactttgct gttttattga attcagcaca gttaaaagga aaaggatttt
     5101 ttagaactgt ctattatatt ccaaccatta catcaacggt ggctgtagct tccgtattca
     5161 tgactttttt caatccgact gggttattca atggattttt gaatgcgcta ggaattaacg
     5221 gtgtacagtg gttaacaaat cctttttgga tacgaatatc aatgatcatc acgatgattt
     5281 ggcttagtgt aggatataac actattttat ttttagctgg tcttcaaggg atttctaaag
     5341 agatatacga aagtgctgaa atagatggag catcgaaatt tcggcaattc tttttattaa
     5401 cgatccccat gctaaagcca atcattttaa tggccacagt tttagccact atcaatggct
     5461 tgggtaattt caatatccca aatatattct ttgggacttc caatggacca gaaaattcag
     5521 ctttggtcgt aggagtcaat ttatataaaa caagttttga aatggttgat tttggaaaag
     5581 cctctgctat tgcctggacg atggtgtttg tatctgttat attatcggct attcaattta
     5641 aattcggagg tgataaaaat gactaaacaa aagatacaaa gcagaatttt tacgtacgtc
     5701 attattgtgt ttggtgcctt aatatttttg atgccatatt tatatatgat tgtagcttca
     5761 acgcaaagta atcaagaaat tttaagtggc ggaatcaatt tcaagtttgg ggatatgcta
     5821 ttaaaaaact ggcaagccat catggcgaga tataattatc ccttgattat ttggaattcg
     5881 attgttattg ctgtaatcag tacagtttta gctacagcca gttctacaat ggcgggttat
     5941 gcattagcaa agtatcgttt tatggggaat aaactgttgt tcaatacagt tatgctatct
     6001 aggatggtgc ctttttttac cacattgatt cctttatttt acattatgag tcgtttagga
     6061 ttatcgaata cttatgcagg tgtgatcatc ccttcgattg ccagtacaac ttcagtgttt
     6121 atgatgcgac aatatagcag tcaatttcct acagcactga tggaggctgc cagaatcgat
     6181 ggtgccaatg agtgggtgat ttttacgaaa atcgctgtac cgattttatc acctacgatt
     6241 attactagtg gtttacttat ctttatggga agttggaatc aatatctatt tccattagtc
     6301 atgctttcag ataaagataa atatacggtt cccttaatta tcaaaaatat gacggtttct
     6361 agtacaggtg agccaattaa ttatggcgca attatgctaa ttttagcaac ttcagtgatc
     6421 ccaatggtct tgatttatgt gtgggcgcag tctaaattta aggagaatga cattggagct
     6481 gcaaataagt aaaaaaaata acgaatgtta accatctagt tcgttctagg agcaactcca
     6541 cattcataaa aattaaaaga atggcgggat atccatgaat gaacagacga aggaatggtc
     6601 aagaaaaatt ttgaatgtag cttctgaaaa gatagatgcg gaattagaca gaatggggaa
     6661 taaaattcca tatatttctt acaacggaaa atatacagac gtaataaagg acagaggaat
     6721 cgactggtgg accaatggtt tttggagtgg tattttatgg cagctctttc acaagacaaa
     6781 acgagaaaag ttcaaagagg cagcaataca acaagaacaa ttattagaat ctgccctgta
     6841 ccatttttca gacgttcatc atgatgtagg ttttttattc ttaccatcgg ctattgcaca
     6901 ttatcaacag tctcaaaaca aacatagtcg acaactaggg ttacatgcag ctacggtact
     6961 tgctggacgc tataatattt cagggaacta tttagtagca tggaatgacc ataaacctgg
     7021 ttggatgatt attgatagta tgatgaattt accattactg tattgggctt cgagggaaac
     7081 tggtgatccg aggttctcta aaattgctcg gcagcatgca gatacaacag ctaagtatct
     7141 agtgaggaaa gatggatcaa ccgggcatat cgcagaattt gatgcagaat cagggaaata
     7201 tattcggtta cttggcgggc aaggatacaa tgagaattct tgttggagca gaggaaatgc
     7261 atgggcttta tatggattcg cgttaagtta tcgttacaca aaaaatccgt actatctagc
     7321 tatagcagaa aagatagcag taaattttat tcagaaaatc gaaaaaactg gttatattcc
     7381 tctcattgat tttgctgtaa aagattcgaa tattgatacc agtgctggag tatgcgctgc
     7441 atgcggtctt ctggaattag caggatatgt ttcctctgta cgatcaaaaa tgtatcatga
     7501 agctgctatc aatatactcc aaaagacaga aaagcactat gcaaattgga atatggatga
     7561 agatgggatc attggaggcg gagcagaagc ataccataga gaactgactt ataatgtgcc
     7621 actgatctat tctgattatt tttttattga aggcttactt cgattagaac agtcggaatt
     7681 agctatttgg tagtaaaaag aggagaaaat acaatgaaac atccagtacc actattaagg
     7741 accagacagg attactttga cttatttaaa aagataaatc aaccactcca gccgttttat
     7801 cgagcaagtg gcgcacaaat tgattatata catcaagggg taggatatgg aaataaaatt
     7861 gcaggaatgg aaggattctc tcgggtttta tggggagcgg ggcccgcaat tgaccaatta
     7921 gatgaacgat ggttgaaatt aattctatca ggaataaaag ctggaacaga tccttcccat
     7981 cccgattatt ggggagaaat acatgaaaga gaccagcgta tggtagaaat gcccgcaatg
     8041 ttattagcgt tatatcatca tgaacaatta ttatggaaaa aattagatac aggagaaaaa
     8101 agccagatta ttcattggtt ctcgcaaatt tttgaatatg aatgtgcaga tggtaattgg
     8161 caatttttta agataattgt cggaacaatt atccaaaaat ttggttatcc agttaaagaa
     8221 tcagcactga aagaagcatt tgataatata gaaaattgtt atcttcaaaa tggctggtat
     8281 cgagacagtt caagaggtcg ccaagattat tataatcctt ttgcatttca ttattatggt
     8341 ttgatttata gcgtactaga accagaaaag cccattagcc agatatataa gaaccgagct
     8401 attgattttt ctagagacta tattcatttt tttgcggaag atggtgcaaa tgtgcctttt
     8461 ggtcgaagca tgatttatcg ttttgcagtt tcaagctttt ggtcagctat gttgtgggcc
     8521 gatcttttgc cttttaaatt aggtgaaatc aaggggttag tcaatcggaa tataagatgg
     8581 tggatgcaaa aagaaatatt tgatgaaaaa ggtatcctga atattggtta tacctaccct
     8641 caattgacat tgactgaacc ctataatagt acgttatctc cattatggct gaataagatt
     8701 tttttattgt tggcgctacc tgaagaccat gagtattgga cggctaaaga aatgcctatg
     8761 cctattcgtg aaggaactaa acttctttca gaagccaatt tgctcataca acatgataat
     8821 ggacatacat tttttttgaa tgcgggacaa ttagggccaa atttccatac attgaccaat
     8881 gaaaaatatt taaaatttgc ttattctagt caatttggtt tttcgatacc gcgagcgaat
     8941 caattgaaag cagaaatggc aatggattca atgctaggga ttcagcgagc ggacacatat
     9001 atcacgacca gttttaagaa tgagagcatc aaaacctatg gacagttcat cgttcgaaat
     9061 aatgtacgag acattgtatg taagaaagag gtacttgcct ctacatggga acctacttta
     9121 caggcaaaaa tcagaacttg gcttattcct tttgaaggct ggcagattcg cgtacacaaa
     9181 gtagaattag atacagaata tgttctatat gagacagggt ttgctattga atgttctcct
     9241 gagaaagaag gaataatcat agaagaagac aaggaaaact atagggtgag tgaagctggc
     9301 ttttcaggta ttatctgttt aagtgacgat actattaaac gaaaatccac agctattatg
     9361 ggtttgccca atacaaactt gatgacatgg gaaaacactt ttattcctgg attagagggt
     9421 acatttggaa aaggaaccca ttggctcgga acaggagtgg ttgctcatca agatcgggat
     9481 tatagtttag aagtatggaa caatcgtccc aaaattgatt ttgatgggac aaccgggcta
     9541 actatccaaa ataaaaacaa taaaaaaaga ctaaaattat gctaaaggct ggtggggaaa
     9601 tgcttgataa agtgatgttt gaagagataa tacatccaga aaaatggata aatgaatgtt
     9661 ataaagaatt aatggaaaaa gaatggaata atgagatcga gcgttgtcgc agacacacgg
     9721 agaggttaat caaacgtatc agtaacagtc agtatcaatt cccaagcgag tgtcctataa
     9781 aaggacgtta tccattaaga gacaatattg gttggacaga aggattttgg acaggaatta
     9841 attggttgtt atttgagaag acgggtgatc ctttatttca acaaacagct gaaaaagcag
     9901 atatagattt tatccacagg attgactgtc aaattatcac taatcatcac gatcttggtt
     9961 ttttgtattc tttatcaacc gtagcagatt ataaaataac gggaaatcga aaaatgaagg
    10021 aagcttcaat tgatgctgca gaaacattac ttcagcgttt ttgggagaag gcaggagtta
    10081 tacaagcttg gggagatcct agtgatcctt cacaacaagg tagaatgatc atggattgtt
    10141 gcatgaatct tccattattg tattgggcga gtgaagaaac tggaaatcaa aaatataaaa
    10201 aagctgctca ggctcatatt caaaatgcag cagattattt agtaagagaa gatggttcaa
    10261 cttatcatac attttatatg gatgtcaaag atggaaaacc aagatatgga agtacgcatc
    10321 aaggttatag tgataattcc tgttgggcta gaggccaagc atgggggatt tacggttttg
    10381 cattaagtta tcgttatttg aaagaacaaa aatattttga tttaagcaaa atattagcca
    10441 attattttat gaatcggttg ccagaagata ccatttgtta ttgggatttg atctttgatg
    10501 attctagcag agaagaaaaa gatacatcta gtatggtgat catggtttgt ggattattag
    10561 aattaataga atcaggtcta ttagacaaaa cagaaaagaa cttataccag tctgctgttt
    10621 ggaaaattat gcgacaattg aaagaaagat atgctacaac ggaagaagaa gatggctttt
    10681 taacacagtc tgtttataat aagcccaaaa ataatggggt aaatacacct tgtatttggg
    10741 gtgattacta ttatttagaa gctttagtga gaatgactag taattggtct tcttattggt
    10801 gaaaaaggta aatatggaat ttttgtttga taaaataaaa aaagaaaaac caaaacagca
    10861 tgaatggttt ctgttttggt tttttcgtta attttcatat tcttctaatt ccaagcttag
    10921 ttcttcccat tccgtcaatt ttgtttcttg atcttgtcta gcagcttcta aatcttggtt
    10981 cagctcattg agttttacgt gatcttccag gttttctggc gcgaccattt cttgttccaa
    11041 ctgatcgatc cattcatcga tccgcgccat ttcttcttca acctgagtaa tttttcgttg
    11101 aaggctacgg ataagctttt gctgttcttt gctttggtaa taatcagatt tgttcgtggg
    11161 agcaggagca gattctggct catcttgtgc caacaattcg gcgatttctt cttcttcctg
    11221 ctttttctct aaataataat catagtctcc tagatagact ttgctgccat tttcagagag
    11281 ttcgacgact tttgtcgcga tccgattgat gaaatatcgg tcatgggaaa caaaaagcag
    11341 tgtgccgtca taatcgatca atgcattttc taatacttct ttgttgtcaa tatctaaatg
    11401 gtttgttggt tcatccaaaa tcaaaaaatt ttctttgttc atcgctaact tggctaaagc
    11461 aacccgtgct ttttcaccgc cacttagcag agggattggt ttttctacat cttcgccaga
    11521 aaataagaaa gcacctaaag cacttcggat ctctttttct ggagtggtag gatgctcatc
    11581 ccacaattct gctaggatcg tcttgtttgt atgcagatca gcttgacctt gatcgtaata
    11641 gccgatggtg acatttgtcc ctagcgtttc ttttccacgg ataaaaggga tctggtgaat
    11701 gattgatttc agcaacgtcg atttcccgat accattcgga cctactagag caatcgcttc
    11761 ttgacgacgg atatctagat tgattggttc agataaggtg acattatcat atccgatagc
    11821 ggcatcttcg atttgcaaga ctacatttcc agaaggcttt tctatactga atagaaagtt
    11881 tgcttgtttt tcatcccctt gaggacgatc cagccggtcc attttttcta atgtctttct
    11941 gcggctttgc gctcgttttg tggtagaggc gcgaacaagg ttccgagcaa cgaagtcttc
    12001 taatttatgg atttctgttt gctgcttttc ataagccttc cattcacttg ctaactgttc
    12061 tgctttcaaa tctagatatt tcgaatagtt acctttgtaa tggcgcattt ttcttctgct
    12121 taattcatag acttcattga ctactttatc taaaaaataa cggtcatggg aaacaatcaa
    12181 taatgcacca gtatagcttt gcagataatt ctcaagccag gaaagtgtct cgatatctaa
    12241 atggttcgtt ggttcatcta gaatcaaaat gtcagggtgt tgcaaaagca tgcgagctaa
    12301 agctaaacgt gtgcgctgtc cgcctgataa agtatcgatt ttctgatcat aaaatgaaga
    12361 atcgaattta aacccatgca atacggaacg aatttcattt tcataaccat agccgtttcg
    12421 atctgaaaaa tcgtgttgca gccggtcgta ttcttttaaa taagaactat aagcaggtgt
    12481 gtctggcgta ccttcgctaa tgaaaatctc tagctcgcgc atccgctctt ccatttgtct
    12541 aacttgttca aaagctttca gcatctcgtt ccaaactgtt tcattggaat caagtcctgt
    12601 gtcctgagcg aggtatccga gagtcgctgt tttattttta gcgatctttc cttcatcagg
    12661 tgcttcaatt ccagcaatga tctttaataa agtcgatttt ccagcgccat ttctgccaac
    12721 taaagcgaca cgagcgcctg tactgatttc taaatgtatg ttttcaaata agacttctgc
    12781 accaaaatgg cgagcaatct gattggcttg taataatatc atggaatcct cttttctact
    12841 ttgtgaattc tcctcaaata aaaaactatt tttcaattag tagtctacca taaattccat
    12901 tatactgcga gatttgcaga aatgataaat aaatgaataa agaataaaat ttcacaatat
    12961 ctgagcaatg gaattgattt tttcctataa atactgctat gatggagaaa tcaaagatgt
    13021 aattagacaa tacgtggagg tcatttcgtg aaagatcata ttattccaaa ggcgacagct
    13081 aaaagactgc ctttgtatta tcgctattta aggattttaa ataatgctgg aaagaaaaaa
    13141 gtgtcttcaa ctgaattaag tgaagccgtt caagtagata gtgcaacgat ccgtcgagat
    13201 ttttcttatt ttggcgaatt aggaaaacgt gggtatggtt atgatgtaga agatcttatg
    13261 cacttttttg caaagacatt aaacgacgat caattgacaa atgttgcgct gatcggtgta
    13321 gggaacttgg gaagtgcttt actaaaatac aaattccatc aaagtaatag catacgtatc
    13381 agttgtgctt ttgatgtgaa tgaggaaatc gttgggcgca tcgtagacgg tatccccgtt
    13441 tatccaatgg aagatatgtc agaacaaatc aagatccaac aaatcgaagt agcaatttta
    13501 acgatacccg ctgaaagagc acaagaagta gtcaatcagt taacggaagc aggaatcaaa
    13561 ggaatcttga actttaccgc tgctcgattg aatgctccgt cagatgtatt gatccaaaat
    13621 gttgatttga cgaatgaatt gcaaaccttg atctatttct tgcattctga cgcaaatgcg
    13681 cattccgaaa atacagcaga ataaaaataa aaagcgattg aacaaatgaa ggcaaaactt
    13741 tcacttgttc aatcgctttt ttctgtttgg acaacgatta ttttgttcgg aagatttctt
    13801 cataagaaag ggaatcatct tctgctgtca gttcatctag tagataacgg atttttttaa
    13861 agtcgatgaa ccgtgcttgc cgaaagactt cttttccttg atgaaaaatc aggacaactg
    13921 gcgcagtcag cacttcaaat ttactagcta cttctggtgt ttcaaatgca tccaaatgaa
    13981 gtgccggaat atcataatgt gtgagaagtt cctctagtcg tggacgaaca gcgtgacaaa
    14041 cactgcaatt aggcatcgaa agataaatga cggcaacgga tgactgttgc agtatgtctt
    14101 gaacttcagt caagttagtg gtttgtttca tttttattct cccttttatg atagaagtga
    14161 tatgtatgag accttaattt aatgggaata acagaaaaag tcaattgaag tgctttggta
    14221 aaaaataaga gttgtgtaaa aatttacaga gcaacttgtt ttttttgaat aaaagcgtat
    14281 atttgcaaag cgaatgaact agaaataaaa aggaggaaac tcatgttttc ttttattcca
    14341 aattcggttt tgcagatgag tacgattttc ttatcgatcg ttattgaagc attacctttc
    14401 gtattattag gctgtcttat ctcaggcgcc ttacaagtat ttttgacccc agaacgtgtg
    14461 aagagatggc ttcctgaaaa tcgtatcttc tctattttta ctggttcgat cttaggattt
    14521 ttctttcctt catgtgaatg cggcatcgta ccgatcgttc atcaatttgt taaaaaaggc
    14581 gtaccagttc acacagcgtt tgcttttatg ctgactgctc cgatcatcaa tccaatcgtg
    14641 attttttcca cttttatcgc atttggcaat tcttggcaga tggcaagctg gcgggtgata
    14701 ggcagctttt ttgttgccct tgtgattggt gtctggcttg cctattttca aaaagacgct
    14761 gtattgaaag aaaaaatcac gtctaaagta gcagaaaatc accatcatca tgtccatgaa
    14821 gaagaacaaa gtgagaagaa tgaaccaaaa aatcagctga tccatcaaac tgggcatgtg
    14881 ttgacacatt caatcgacga attttttgat acaggtcgtt atttgatcat tggcggatta
    14941 atcgcagctg cgatgcagac ttatttacca actagaatta tgctaacgct cggctcaaca
    15001 aagattttag ccattatcat catgctgtta ttggccttta cgatgtctct ttgctcagaa
    15061 gcagatgcgt ttataggatc ttctttgtta agtctgttcg gcacagcacc tgtagctgcc
    15121 tttttggtct ttggcccaat ggtcgatatc aaaaatctac tgatgatgaa acgatatttt
    15181 acaggacgct ttattttatc gctgatcgga ctgattgccc ttagcgttat tggattcaca
    15241 ttatttattt aggagggaaa atatgctgcg gtttttgatt ttatctgggt atttcgaatt
    15301 gatgatgtac ttgcaagttt ctggcaaact cgatcaatat atcaatgtcc attatcgcta
    15361 cttagctatt ctttcaatga ttttatctgc tcttttggct ttagttcagc tgtatttgtg
    15421 ggtcaaaaac ggaaaagcag aagaaaaggc acacgagcac gatcatgacc atgggttgtc
    15481 aaaaccttat caacgtggaa tcgcttatgt actgctagct ttgccagtaa tcgtggggac
    15541 gttgtttcca acagttagtc tcgacactac gatcgtagaa gccaaaggat ttaatttccc
    15601 agtaagtaaa gaatcagtag gggatccgga gatgcagaca caatacttaa agccggatac
    15661 cagtatttat ttcaacaaat cagactactt agaccaaatg aatgagttga aagaaaagta
    15721 tggggataag caaactatca agatcacaga tgaaaactat ttagaagtta tggagctaat
    15781 ttataattac cctagcgaat tcattggcaa aaaaatcagc tatgaaggat ttgtttacca
    15841 aacaccgaac gatagcaata cagatatctt cttgttccga ttcggcatta tccattgtgt
    15901 ggcagattca ggagtctttg gtttgttgac gcatatgccg gaaggagtaa cggttaaaaa
    15961 tgatgaatgg tataaaatag aaggaaccat ccaatcagac tattatcaac cattcaagcg
    16021 tgaaatccca tctgtagttg ttacaaacgc tgagaaagtc tctgctccga aaaatcagta
    16081 tgtgtatcgt tctttttaaa agaacaaaat aaataaacat agctcagaca gctgacacgc
    16141 aaggacgtcg gttgtctggc tttttttgca tgatgtattc atttgtttga tatttatttt
    16201 agaagcagca tcctgaaagt atttgatatc ggtttcaaag gtgttggaaa agattgtgaa
    16261 gagaattaca atttattcct aacatgtatg ttgaaaagtt gtatgaaatg attttgatag
    16321 taaaatatcg agtggaggta ctttttatgg taacgcgtat atttattttg gatgatagtt
    16381 tggtttttga aaaaatgcta gtagaaattt tggaagaatc cagaatttta ttaagtcctt
    16441 ggaaatttga gatcgttcag ggattgaacg ttatacaatt tgttgaattc attaaaaata
    16501 atgaaatcta ttcctcagat atttttttcc tagacatcga tttgaacgcc tattatagcg
    16561 gtatcgaact aggcgaaatg cttagagaaa agaatgaaaa gtgtaaaatt gtttatctaa
    16621 cgtctcatcc gaataaagca ataactgtta ttaatcgaaa gattacgcct agtggttatt
    16681 tgataaaaga attcacttat gaaaaaaata aaaaaagcat ccaaagttac ttattgaaag
    16741 aaaaagaaaa ctatcctgtt caacatgcta cgaaaaaaag gtggacaact gtccgttatg
    16801 gtaatagcga tcactatatc cattacgatg aaatccttta tctaatgagc atgccaggtt
    16861 ataaaaataa aataggccta gtattgaaag atgaagagat tctcgtaaac ggcacaatta
    16921 aaaaatataa aaaatcactc gaatatgagt atttatgtaa agatttaaaa gcttatatca
    16981 ttaatactga aaacattaca tctattagca gagtaaacga aatagtaaca tttgcaaatg
    17041 gagaacaact agagatggga aagagaagta ttgataaact aaagaatttt atgcaagaaa
    17101 agatagaaaa tgaatcattt taaagaaaac aaagactcat atcttacctg ttagaagagt
    17161 gttttcctgt agaagagaac aacccaagta gcagcctagt cgtttctatc cttttttgtt
    17221 atgcactctt tttgacattt actccaccaa taacgaaggg tacaataaaa agtaataaca
    17281 aacaaaagga gtacagaaat gattgaattc atcaatgtaa gtaaaagtta cgggaaaaaa
    17341 caagcattaa aagacttgtc tctctcgata agacaagggg aaatttttgg atttttagga
    17401 cataatggtg ccggaaaatc aactacgatt aaaagtttag ttagtattat tgaaccatca
    17461 tcgggaacga ttttagtaga tggaatgaaa ttgacggaaa atcgattgag tatcaaacaa
    17521 aaaatcggtt atgtgcctga ttccccagat atttttttac aattgacggc tggagaatat
    17581 tgggacttga tttcagctgc ctatgaatta gacacacaaa aaaaagaaaa gcgtttagca
    17641 gaattgacag cgctttttga tatgtatagt catcaaaatg aaacaatcgc aagtttttca
    17701 catggaatgc gtcaaaaaac gattttgatc ggcacgttgc tgccagatcc agatatttgg
    17761 gtattggatg aacctttgca aggacttgat cctcaagcag catttgattt gaaagaaatg
    17821 atgaaggctc atgccgcaaa aggaaaaaca gtcatttttt ctacacatgt attggatacc
    17881 gcacaacagt tatgcgataa actggctatt ttgaagaaag gtgaattgat ttatcagggg
    17941 gcagttagtg aattattgaa tggctcacct gatgaaacgc tagaaaagat ttatttgaaa
    18001 atggctggaa ggcaagcgac aggagatgga ccgtatgtat aagcgacaat tattagaatt
    18061 aattcgagtt aatcttttat atgttaatcc acagctcacg aataaagcaa gagagaaagg
    18121 aaaaaaggga aagcgattaa ctatctatct tttgtctcaa aatctttttt cagggctgat
    18181 ttttttactg atttacggat ttgctatgtt tgctatgaac tttgttaaat tgccaggttt
    18241 ctttacttat tacgtggcac tttttggtat gttaggttta actcaaagta tatcagtcat
    18301 ttataatatc ttttttgaag gaaatgacct gcaagtattt ttgcctctgc cttttggaca
    18361 agaacaggtt ttttcagcaa agattttggt agttgctttg accatcattc cttttgtttt
    18421 tccgcttcta gtcatgttta ttttaaccgg atggcgagct gatctaggga ttttgcttac
    18481 tatcattatc tcaatccttt tgttttctct atttttgatt attctttttt gtctggctag
    18541 tttgattgtt tttggtttgg ctcgaacagc agtgtttaaa aaacatagaa aaacagtttc
    18601 tagtatcttg cttggcagct cgatgctgat cgcatttgct ggaatcatgt ggatgaatca
    18661 tcaaacgggg actattgaaa atgagttaac agatcggcat ccgatttcga tattattgcc
    18721 attctatgat gctgccagtc agccactttc tcaacaaggt ttattgggtt ggggaatact
    18781 agctatcacg gctctgggat ttttccttgc tgtaaaacag ctgatagtac caaagcttac
    18841 agagcaactg actgattcaa acagtgagtt caaaataaaa agaacccata aaaagaacca
    18901 aaatgtgcat cagcttttat ttagttacaa tgctcaatta gtaaaagaac ctaatttgat
    18961 tatgcaagtt ctttcttctt ccttgttaac tccaatcatt tttattcttg cttttgccct
    19021 aggaggcgaa ataaaattaa ctgatttaga taataagtta atcggtgttg ttttcctggt
    19081 agggatcgca ttggctttct taacagttaa tcagacttct tttatcagca atcttatttc
    19141 tttggatcaa gaaaattttc tgtttatccg ttctttgcca atctctatga accaatattt
    19201 aaaagaaaag ttcagattcg gatggatatt gcagagtttt ttaactggtg ggatcgcatt
    19261 attaagcgga ctgtcttttc agctgccttt gttttttatc cctagcttgc tatttggttc
    19321 tttattcggc tgctacttat tgtcactacg ttatttcgct agagattatc ggttgctgct
    19381 gctgaactgg accaatatta accaattatt taacagaggt tcaggaagtt tgggtttagt
    19441 cgcaactatg atgggttcat tgatcatcag tattattctt atcgtcttat acggaatgtt
    19501 ggctttgttt tatccatttt ggttagtgaa tattcctgtg atcggtttag ttctaatact
    19561 ttccgctcta tggatcgttt attatcaacg aacgttttgg aaaaaatttg aataaagaag
    19621 aggggccgtg acaaaaatca tgtcgcagcc ccttttttac agatagaggg tgttcaaaag
    19681 tcagtttctc agtattaagt caattttatg taaaaatgtg agaagctatt tttacaaaac
    19741 tttttttaat actcataatt acttcttatt gctcctgcgg ttacttgtcg caatgtttgt
    19801 gagatatttt gtcatcgctc aaggctgaac gtctctttca caaccttttc tttgttacac
    19861 ttcgtttatt taaaaagccg tttttttcgt ttcatcatga ttgcgtcacg ctttactttg
    19921 aaattacgga tgttatggtt aaagacttct gataatacaa gacctaaagc gattgctcca
    19981 gcaatcataa ttgcttggac cgcataatga gccgcttctc gataggattc agtaacgaga
    20041 tttcgaaccg cttgataagc taaaccacca gggactagag gaaccatccc gggaatattg
    20101 aaaatcgtta cgggcatttt caaacgttta gagaaaagat cgctgatgaa tgctactcct
    20161 aaagaaccaa gcaatgaacc aaaagcagca gatccgccta tttgaacaca gatccagtag
    20221 atcatccagc caaaagcacc agaaagacca caacaaatca atgaacgcct aggtacattt
    20281 gtaataacgg caaatgccgc agtcgctaaa aaactaaaag aaaactgaat aaatatcgtc
    20341 cccatacttg tgttcctttc ctaataaaaa agctggaaaa taaaagcaat cgcaaaaccg
    20401 atcatcgtag cagtcatcat cgcttctgtt ccgcgagaaa ctcctgagac ataatgtcca
    20461 gctagcaaat cacggatagc gttcgtaatt tgaactccag gaactaaagg catcacacat
    20521 ccgataatga ttagatcctg attgcttcct aagccaaaac gtacgctgta gatagcggct
    20581 atgccaatca ataaagaaga taaaaattcc gataaaaatt tgattctaaa aaatttcaaa
    20641 ctatatagat aagctgcgta tcccaatcct ccaatgacta aagtcacagg taaatcggtc
    20701 atctttccgc caaataacac cataattgtt ccactgatca ctgccgcgct aacgatttgc
    20761 aaccagacag gaaagaaaga acggtctcgg tcgattgctt gcagttcgca gtaaagttct
    20821 tctaatgtta gctctgaagc aacatattta cgtgaaagat catttacttt tactactttt
    20881 tctaaattaa tcgaacggtt ggtaatttgt tccattcgga tggtcgaggt acgatcaaga
    20941 ccaataaaga gaccggtttg agtgacatag ctgaccaaac ggaaatttcc agaagctaaa
    21001 gcaattcgac tcatcgtatc ttctacccga tacatctccg cattgctttc catcatgatt
    21061 ttcccagcga gtaaacaagt gtccagcaac agatctaatt cttttcccgt catagcatct
    21121 tctccaataa ttgattgatt agttttattt tactacaaaa cataccagaa gcgtaaagaa
    21181 taaaaaaact tgaggaagga ataaaagagg cgtatactgt ttttgtattg cgggtgtagt
    21241 ttagtggtaa aatcccagct tcccaagctg atgtcgcggg ttcgattccc gtcacccgct
    21301 taaaataggt tgtgaaaaag ctgctctgca acaagtaata agaacagcca agcaaaaaca
    21361 acttcttatg tttttaactt ggatggactt attaccgcag atgcaagctt ttgcgcaccg
    21421 tttaccaagc ggttgtgaaa tcagtgtatt gtcttgagta tgaagaaaat ttttgaataa
    21481 taataaatac cttacagata gagtggtgac tgattagaga cgaggaatcc gtctcttttt
    21541 tgtattttta agccatctta aaacaggttt tattttttgc tgtttctatt tctttctagt
    21601 atttatttat aggggaacat atgttaagat ttagggagct gttagtaaag gagtaaagaa
    21661 atgagcaaaa aaacaaccaa ggcgatcgtg gggatcgtcg ctgctgtgat tgcaggggca
    21721 ttcggtgttt ccaccacaca aaaagattca gatatctttc agcagattac aactattttt
    21781 gattccacac cacaagcttc tcaagtagcg gatgtgccag aatatgatgg aaaacatcaa
    21841 gaaatagaaa tcaatgggaa tcagccggaa tttacaaaag aggatcttag cctttccaaa
    21901 ggaacatggg aaagctattc aaatattgat aaattgaaca gagtaggaca agccaatgct
    21961 atgcttggaa aagatttgtt ccctactgaa aagagagagc ctttgtatat tgacccgaca
    22021 ggttggaaac aaaagaaatt aagtgacggg caatggttat ataatcgcag ccatttaatt
    22081 ggtttccagc tgactggtca aaataacaac attaaaaact tgatgacagg gacacgttcg
    22141 ttgaatgctc catacatgct tgctcacgaa aatgatattg cggcatatat caaagaaaca
    22201 aatcatcatg tacgctaccg tgtcactcct cattttgagg ggaatgaact ggtagccagg
    22261 ggagtgcaat tggaagcaga aagcattgaa gacaaaaaaa ttgaattcaa tgtctttatc
    22321 tacaatgttc aagatggcta cacgatcaat tatgagacag gacaagcaac aaaaacaaaa
    22381 aattagtagc agctattcga attttttatg aatattatga aaaaattgtg taaaaacata
    22441 cattcaaaga aatatagcgt atactttatg aaaagagtac ttttgataaa gctacagaaa
    22501 aaaggaaaaa aacatacaaa tagtgtttct taatttattc ggaagtttgg aatatttgtt
    22561 tgtagttttc cctttcttcg agtaaaataa ggttgtagaa ggtaagctgg aattaccttg
    22621 cgggaaagag gtgtagaatc atgggtttta cagatgaaac cgtacgtttt ggttttgacg
    22681 atagtcgcaa aaaagaagtg agcgaaacat tagcgattgt ttatcgggct ttggaagaaa
    22741 aaggctacaa tccaatcaat cagattgtcg gctacttgct ttctggagac ccggcctaca
    22801 ttcctcgtta tcgtgatgct cgaaatttga ttcgccgtca cgaacgcgat gagatcatgg
    22861 aagtaattgt caaggactac ctctcaaatc atggagtgaa tttatgagag taatgggctt
    22921 ggatgtcggt tctaagacag taggtgttgc tatcagtgac ccctttggct ggacagctca
    22981 aggagtagag atcattcgga tcaatgaagc agaagaagag tttggctttg atcggttgaa
    23041 ggaattagta gcacaatatg aagtagaccg gtttgtagtt ggattaccta aaaatatgaa
    23101 caattccatc ggaccaaggg cagaagcttc catgtcatac ggagaaaaga tcaaagaact
    23161 attctccttg ccagttgatt atcaagatga acgattaacc actgttcagg cagaacgtat
    23221 gctagtagag caggcaaata cttcaagagc caaacgaaaa aaagtcatcg ataaattagc
    23281 agctgtgatg atcttacaaa attatttaga cggctcaggt aagcaattat tttaataata
    23341 aaagaaaaga ggtaatctta tgacagaaca taaccattcc cacgaccatg aaggacacga
    23401 acacatcaca ttggtggatg accaaggaaa tgaaacatta tatgaaatcc tactaacagt
    23461 tgacggacaa gaagaatttg gacgtaacta tgttctttta tatcctgctg gtgtttcaga
    23521 agatgaagat gtagaattac aagcttatgc atacatcgaa aacgaagatg gaacagaagg
    23581 cgagttagaa caaatcgaaa cagacgcaga atgggacatg attgaagaag tattcaatac
    23641 attcatggcg gaagaagaag aatagactat aaagctagga gaaaccttga tatgataggg
    23701 tttctccttt ttttattttt tactgtatgc catattgtat gccatctagt caatatttaa
    23761 gtgttgtact aatttttcaa cagtcttttc tttcgtttct tttgccaagt gaccgtaaca
    23821 atcgatcgtc tgactaattt ttgtatgccg taatctagtt tgaacttcta ccatagtagc
    23881 tccagcgtcc aagagcattg aagcatgagt gtgtcttgct acatgcacac cgagaaatgg
    23941 aaccatagct ttttcacaaa tagtaatcaa tcttgcataa atagcgtggt gtgtgattag
    24001 ttctttatag ataccacaaa aaatcatagt cggatcagtt acaccaagtg tcagcatata
    24061 tttccgctga ttaatctgcc atttttttaa tatagaaatt gttctttcat ctagtggaag
    24121 aaccccagca ctacaatcag ttttaggatc actgatttta tagccatttt tggattggct
    24181 tagtgtttta ttgatggtga ccgtattttc ttgaaaatca atgtctgacc aattcaatgc
    24241 aagggcttca ctgatcctaa ccccgctata aaagagaaag cgtagtaacg ttttatcaaa
    24301 gtcgtttcga taagtttcag gtttgctgtt taggtaatca aacaaggtga tcagttgttc
    24361 tttactgtaa actttgacct tttctttatg cttagtggtg gttcttttag gcattaatac
    24421 gttgtctagt ggattagtct caataatccc aagattgata gcgtagctaa aaatacgctt
    24481 agaagttgaa tgaagtacct tgtattggtc agtagtttca gcccagctat ttacaatttg
    24541 ttgggctttt tttaccgtga cttcattcac acgaagattt ccatattttg gaagaatcca
    24601 ctttctaaac ttgatttcag ttttcatgaa ggtggcttct cggacagtgg ttttatatgt
    24661 ttctagccac aagtcataaa cttctttaaa cgtttcgttg ttcgcttttt taataccgtt
    24721 tttatcgtag tccacttgca agcgtgacaa ggcaagctgg gcttcttttt ttgttttgta
    24781 acctcgtcta cgaaccttat caggtttgcc agtcattttg ttcattccaa gataggcttc
    24841 atagagccaa aatttacctt ttttagtttc atattgcttg aatgttgcca taatagtttt
    24901 ccctccatag tgtagcaagc cgtgggggcg gttggaggag gcagtttatt attattttga
    24961 atagtgttta tttagctcag taacaagagc tgtgaactct tttagaagat cattttcata
    25021 aaattcttga tactcttttt tctcatctgt atttttttct gaatcattaa ttaatgagtc
    25081 atatcgtaaa agcgtattta gaagagctgc gagataagca attggggtac tcccgtcagg
    25141 aaattcaatt cgagatcctg ttttaagata ttttattgcg tttgttaaat aaatcttctg
    25201 tgagacagtc aggttatctt cttcgatgtt attgatagca ttagaaagat tagaatcaat
    25261 tatagagtta tttttttcaa tagttttttt caattgcttt tcaagcacat ttcgcttaat
    25321 ttcgggcatc atatgcatat ctcttaatgt ataagatccg tttaatagat aggtagtgga
    25381 tacatctaat acctttgaaa gttgtttaag cctggtgtta ttgggaagat tatagccatt
    25441 ttcccaatta ctaacggcac ctttactggc cggtggggat aatttacctc caagttgttc
    25501 cattgagagt cccttttcaa ttctagccag tctaattctt tgtcctgtct ccactgcttc
    25561 ggggtatttt tttctagcca cattttcacc accattcata tattttctct actatatcac
    25621 gatttaaata tgtgtgaaac ataaaagttc aaaaaagtat gttaaaattc ttgcaaatga
    25681 aaaggtatga tggtatattg agtttataag aggtatagaa atgtattcaa gagcctcttg
    25741 cattttttta aaatctttgt atagaaatgt atgctaacga ggggggataa atatggaatt
    25801 aaaaattgac aaactcacgc ttgatgatcc agcttttaaa attattgacg atcgagttgt
    25861 tcaacaagta gagcaaactc aaggaacgtt actttcatta ttagaaaaaa agtaccagtt
    25921 tccaaaatat atgaacaagg cacaagctgc taagtatatg aacgtttcat acaatactat
    25981 gatgcagaaa tatgttccta acggtttaaa gttgattata gttgatggag tcgtaagaat
    26041 ttcacaagat gaatgtgatc gctttatgga agaataccaa aaataaacgc aagccgtggg
    26101 ggcaaaggga ttaataggag gaaataataa tggaatcgac acaaaataaa gcaatcgaaa
    26161 aagtattatc aacaattctt acagaagaca cagcggcaga attagcaaac ttggaaggca
    26221 aagcgctaga agaaacgttt gaatgtttgt acgaacaaat ggactatcaa aaattgctac
    26281 cacaagaacc aacggtaagc ggagtattgc gtggcttgaa cgatttagta caagcagagt
    26341 ttaaagaacg actttctatt gaagagtatc aagaaatttt gtatcagcaa gttgagttgt
    26401 tagcgagctt gctagggctt gaactggagg acgttgaatg aaaactgaaa tttggaacgg
    26461 acacattata agatttgtcg atattaatga tgaatggtgg gcagtggcga aagatgttgc
    26521 ggaagcgtta ggtcttaaac aggttactag agccattcac tctttgccta aagatggggt
    26581 tactactagt aaggtcatcg attcattggg cagaacacaa gatgtaaaca tcatcaacga
    26641 aaaaaaatat ttaccgcatg gcattcaaaa gccgtaaaaa agaagccgag gcatttcaag
    26701 actggatttt cgacatcatc aaagaactac gccagtccac aggacttgaa ggctttcaag
    26761 tattccgcat gctagacaaa gaacaccaaa aagaagcaat gactaaatta agccacgcta
    26821 ttactgaacc aaaaccagta gactacatta aagcgaatgt gatagccaat aaagctgtat
    26881 caactattta tggtcattcc aaaatggtaa aaaagaaaga tatgactcct gaaatgttgg
    26941 ttgatcgtga acctatttta gatgagacag tagaattaat gactgttaaa gaaaaatatg
    27001 ggttgcagtt ttcagtgagt gagaaaattt ataatcgttc tgctgaattg cagacaactt
    27061 aggagcatta acatgatcga gaacaaagaa aaagccttat ccataacagt cttggcggac
    27121 aggataaagg caacttaatt gggataaaac ccgatattct ttgttccgat tataccatat
    27181 taaaaaatcg gagggaacca ttatgaaacg aaacttaatt ataggaagca ttttaatcgg
    27241 cggaattttc ggcttattac cattaattgc aaaaatagct atctttgcag gattagcgtt
    27301 atatctcttc actgcttatg acgagtacga ctatcaatta agaactggag ggcataagta
    27361 gatgtacaaa acaaaactat taaaccaact cgatagcctt gaattagagg aaattaatca
    27421 agggatcgct gaactagaaa ataatatcgg gaaaacctac tttggaaatt cattcaatga
    27481 aaaactaaca gttttgtatg tactcaaaaa acatgcagaa cacaaaataa tttgtcgaga
    27541 aatcaacgag ctaaaaaatc agattttaac cgcatggtta aacattactg atatgcaaga
    27601 agcaagggtg aaaacattta atacatgggt aaagtatcag aatcaattaa aaggtgctga
    27661 atttgttcgg gatgggttga aatacgaact tgagcagttg aagctcatgg aggtgtctga
    27721 atgatttata ccagtatttt gaaaaaggag gagaggttta ttggcaaata attatcaagc
    27781 agcaacggaa ttacaaaagt cgggatggtc aatttatccc ttatctcctg gaactaaaat
    27841 tccaataaaa ggctctagtg gttggaatga tgcaactaac gattctaatc aaattaatga
    27901 atggtggacg gaagatgcaa ctagaaatat tgggttaatg cttgaagatc atcaaatggt
    27961 ggtagttgac ctagatcaac attctgaaac acgaaacggc gttgagaatt ataaaaaact
    28021 tgcttcaatg tatgatccat ttccttctac ttatacggaa atcacaccag gtaaaggaat
    28081 ccatttcttc tttaaaattc ctgatggtgt aattatccaa caagaaacag gtgcatttgc
    28141 tgatatcttc gggcgtgatg ataaaggtaa aagtttaagc gggattgata ttatcactaa
    28201 aggagttcca atagcgccaa ctatgattat ttcaagaagt gttgggagag catatgaacc
    28261 tattgaaaac gtatctctaa ataatattgc accagctccc gattggctag tgaacctact
    28321 gctaaaaaaa ccgcaagaaa taaagactca ataccgaccc gtagcaaaaa cagggacagc
    28381 aaaaaaatta gatatgattg ttcaaggcgc tggcgaaggt agtagaaacg atcatttaac
    28441 taagttatgc ggttggttac tatggcacgg tgtagataat caaactttag cagaattgat
    28501 ttatacagca aatgcgtaca atgaaccacc gctaaaagat aaagaagtga atcaaattat
    28561 tcgatcgatg attaaaaaag atttgagggg gaaagctcat ggctcataag cataaattag
    28621 atagtatttt agactttccc gaagccagcg agcgtgaaga caatatcatt gaattgaaaa
    28681 cctggatgtc acgattaaga tgcaataaag acgatcagat taaaagtaac agtgttgtga
    28741 atgcagaatt gattttaacc aatgatagca atttagctgg aacaattgct tataacgaat
    28801 ttagcggata cattcaccta ttaaaagatt ctccttggat caatcgtacc gctggagaat
    28861 gggaagacag ttttgaggat gccttaacgg catatattga agaaaactac aatgtagttt
    28921 ttgatgacaa caaaatacac aaagcagtag taaatgtggc tagaaagaat gttttcaacc
    28981 cagtaaaaga acgtatcgaa aaagttaaat gggatcaaca gcctagactg gaaacactgt
    29041 ttattgacct tttaggggta gacgacaacc tttacacacg agaagtaaca aaacgttgga
    29101 tagtcggatc agtcgcacgt atctataaac caggaataaa gtttgagatc gttccagttt
    29161 tggatggacc gcaagggatt ggtaagagta ccgttccagc attactttac acggatgatt
    29221 ttttcaccga ttcattagat tcgctaggtg aaaagaaaga tgattatatg cagcttcaag
    29281 gcaatgtaat tattgaactt ggagaattat cttcaatgaa caaaactaaa attgaacaga
    29341 taaaaaactt catcagtgcc aagatcgata aaattagacc tccttatggt cggaatgtca
    29401 tagcttgggc aaggcaatgt gtatttattg gaacgtcgaa tgatgggcag tatttgaaag
    29461 atgatacagg aaaccgccgt ttttatcctt tgccttgtaa gaataagcca aagatgaatc
    29521 cgtttaaaac aaaggatgaa tattttcttc aagtgttagc tgaagcaaag gtgctttttg
    29581 ataaaggaca acgaatctat tttagtcccg atgaagataa agaagtctta gaaattgcaa
    29641 aagactatca agaggatgcc aagatggaga atccaattaa agaagcaatc actaaatatt
    29701 tggaaatgga aatcccgtat aaatgggaag aagctccagc gtgggcgaga cgttcttatt
    29761 atcagaacta tcctgacagt aaatgtaatg agaaaaattt acagcatttc tataatggag
    29821 ctactatgca acaagagttt tatttagttg atagcgtact caccgctgat attttggaag
    29881 ctgtttttga taaacaagca aaggatttat tgaatggtcg atcagatgca gaaactaaaa
    29941 agattgcctt gattattagc agtattcctg gttgggaacg gaagcaactg ccaaaaagaa
    30001 ataaacgacg aggattttac aataagtcaa atgcctatga aaataaaaat cgagctggaa
    30061 agtacaaaaa gtaacgggta gtaacgggtc agtaacacct agcccgttac tagtttaccc
    30121 ttactgcccc aagggataca gcaatttggt aacggggtaa caccttattt ccttaaaact
    30181 tttgaaatag ttagctaata tgctggggaa taatgttact ggattttacc cgttacctgt
    30241 taccaaaacg ctagaaccct tgtccccgtt gggattgagt ggtaacgggt acctgttacg
    30301 taggtgttac cacgtgttac gaatcaagga ggaaagtaaa tgctcaatat tatttcaaca
    30361 aacaaagcac cgaactttca atatacagat gaaatggatc ggtttctaat gaacacgctg
    30421 gcatttagtg tgggattggt aacagaagat tattccacat ttgatccaga agtattaaag
    30481 ataatggaag aagaacctga ttggctgcag gagtcagtag cgtggtgtca atcgctagta
    30541 gtgggatcat tggtagatag tggcaactat gatgatacag gtgagctaat ggatgaattt
    30601 aattgtctgc ttaacctata tgatcgagcg agacaacgag agcttacatc gaatgaggat
    30661 aatttgtttt taaacatcca tgataagttc ttggctttgc tactaacaga tgatgaattg
    30721 ataactaatt tattggaggt agaataatta tgcatatgga aagtattaga tacttcgatg
    30781 gtgagaaaca cattgagtat tcaaacactc aagaagatgt agactttatt agttttgagg
    30841 aagataaaat cactaaagtt aattttaaag acggaacgtg cttgaagata gtttcgcctt
    30901 atattgaata caaatcaaaa tgggaacaag atgattctga cgaacgagat cgctttggtt
    30961 ggtaatctat ggcagttaaa aaacaatgta atcatgctgg atgtaaaaca ttgattgatt
    31021 ataggcagaa gtattgtggg aagcataaag caaagcaaac ggcaattaag cgtgaagaaa
    31081 gaaagcaaag cgaaggtaaa tattttcaat tctatcaaag tagaacatgg cgaaaggctt
    31141 catacttgta tcggttaaat catccagtat gtgaggattg cctagaagaa ggcttgataa
    31201 ggaaagctga tgttgtagat cacaaaattg aactaaaaga tgattggaat agacggttag
    31261 atgaaactaa ttttcgttct ttatgccatg cacaccataa ttccaagaca gccaatgaaa
    31321 gacaaagacg agaaaagagt accctttgag ttaagggggc atagtgtgaa acttactgac
    31381 aatcgatgcc tactcatttt ggtacaaata accgttgtga aaaggcataa gggtaattac
    31441 aaataacgat tacacttgta atcacaagtg aaaaagtata taatgaaagt aggagattta
    31501 ttgaaaaata caattgttat tactgataaa acagggaaac agcgcaccat tgagttacct
    31561 cattttggtc aagtgaccat tcaaatgcag aacggaaaaa tcatttatat agataaatta
    31621 gataaagaaa aattctgatc gaaaaacgaa ggaatgtgag cttaattgct tacgttcctt
    31681 tttcttttgt ctgaaaggag gacaacatgg gacaccctaa aatattacac gatacaaaag
    31741 gcaatatatc aagtgaagaa aaagcaatcc gtgtggacgc tagagaagaa ttgttcaagc
    31801 agcaaccatt aataaatatc acgccccctg actggatggc agcgagcgct agaagtgaat
    31861 ggaatcgtat cgtaccaaca ttaaaaaaag attatccatt gagtgaagca gattatggtt
    31921 cattggtagc ctattgttta gcctttgctc gaatgaaaac agccgaagcc gagataagaa
    31981 aatcaggtac gtttatcaca tgcgaaaacg gagtaaagaa agccaatcca gcggttcggg
    32041 ttcaatcaca agctatgagt gatttgaaaa aacaagccac ctcactaggt atgaccttag
    32101 aatcacgatc aaaactagct ttgaacaagg ttaaaaatga tgaacccgaa gacccgttca
    32161 aagagttgat gaattcatga atgattacat tgagaaagtc ctatcaggta agctgattgc
    32221 acccaagaaa attatccaag cgtgtgagcg tcatataagc gatttggagc gttctaagtc
    32281 agatagcttc ccttatgtgt tcgatgaaga acaagccacc aaagcgatta aattcattga
    32341 gttgctacca tctacggacg gtaaagcaat caagatgtta ggatttcaaa aattcattct
    32401 aggcagtctt tatggctggc gtactaaaga agggaattac aggcgattca atcgagcgtt
    32461 taccagtatg agccgtaaga atgggaaaac gtatatcgca agtggcatgg ctgccaatgc
    32521 gttgattatg gaacaagaac cagcagaagc aaggcaagta ttgtttgtaa gtaacgcttt
    32581 gaaacaagct aaattgggct atgatatgct gtctaattca cttagaaacg tggtcaagtc
    32641 tagtaagttt ttaagaccac aactgaaaat tatgaactct aagattcagc acttgccctc
    32701 taattcgttc gctatggcac tggctagtga aaccagcacg ctagatgggt ttgcaccaac
    32761 aaccgcaatt cttgacgagt ggcacgaagc aaaaactcgt aaaacgtaca acgtcattaa
    32821 gtcaggaatg acccaacaaa agaacggctt attgtgtgtt attagtaccg ctgggcttga
    32881 tttaaacgtt cctatgtacg aggaatactt attgttagat cgtgtgctaa aaggcgaaga
    32941 acaagccgac aggtacttta tagcgatatg ggaattggac gatcccgaag aaattcacga
    33001 tcaagagaaa tggatcaaag ccaatccgat ttttgaaagt gaagaaatca aaaaagtaat
    33061 gattccaacc attcaagatg atgtgaacct tgctttgaaa caaaataacc ttaattctgt
    33121 attggtgaaa aacttcaatt tatggagaca agcgagtgag gacagctata tgattgctga
    33181 agactggcag gcaaccgaag tagaaccaca agatattaca ggcaagcccg tttatatcgg
    33241 agtggattta tctaaaacag atgatttaac tagcgtttca tggatcgtac cgctagataa
    33301 cggcgaactt tattgtgatt cacatagctt tgtagccacc aaatatgggc ttcaagacaa
    33361 agaaaagcgc gacggtttgc cttatcgaga actagaaaaa gctggtgagt gttccattac
    33421 tcaattagaa agtggaatcg tggactatga ccaagtattt cagtttattc aagatttgat
    33481 tcaagaaaat gatttggaat gtatggggat ttgttatgac ccgtataacg ctaattcgct
    33541 tatcagtaaa gctgaaaaag ccaactaccc aatgttagaa gtaagacaag gaacgattac
    33601 tctaaacgtt ccgacccgaa cttttagaga acaagtttat gaaggcaacg ttattcacaa
    33661 taaaaatacg attctcaccc atgcagtgaa caacgctatt ttaaaaacgg ataacaacgg
    33721 cattcagatt aataaatcaa agaacagtaa caaaattgat ccaatagctg cattaatcaa
    33781 tgcctatgtg tttgcaatgg attacttcac cacaacggaa ggagcgaaag cagacaatga
    33841 attttataca agtgaagaat tttctttcta attacattca taccgttctt ttacttcttg
    33901 gattggtgtg tgtgttggtt gctatcacct tactaacaaa tgtctactat ggcttgttag
    33961 cgctgggcat agtgcttatt ggggtagcgg tcatgctaaa tacagaacag aagggaggtt
    34021 aaaagatggc attttttaaa gcgagacaaa atacaacggg agatcctttc ctacaacatg
    34081 tggtatcaat ccaatcggat gattacacca ccagctttac aagcgttcgt gcattaagaa
    34141 atagtgatgt gtttgcagcc gttcgaatta ttgctagtga tattgcttca agtccgattc
    34201 aattggtcaa aaacaatatg ccacaagctg ataatgaact ggtgaagtta ctaaacgaga
    34261 aacctaattc agaaatggat ggttggcatt taaagtttgc tttggcggtc aatatgttgc
    34321 taaacggtaa tagctttgca gagattaaac gcaacggtga aaaggtagaa gaaattcact
    34381 tattacctaa ctcaagtgta acggttactc aattagataa tggtacgttg tcttatcaga
    34441 ttggtgataa aaaaagacgt gtgaagtcta gcgatatttt gcacttcaaa tatttcaccc
    34501 aagatggttt aacaggatta ccaccacttt atgcgttacg tgatgaactg aaaattcaac
    34561 aagctggcaa ccgcacattg cacaatttct ttactcgtgg tgtcagtggg tcaggtattt
    34621 tgaaggttca taagtcagat ttagacggat cagcaaagaa cgcaattcgt gaaaagtttg
    34681 aagaagccaa cggttcaagt agtggagata atgctcttag aacgatcatt cttgatgaaa
    34741 caatggacta caaaacatta gaaataaaca ccgatgtttt gaagcttatc aattccaatg
    34801 attggaacac aaaacaaatt gccaaggcgt ttggtgtacc gattgagcgt ttaggcgttg
    34861 aaaatgaaca ttctagcacc gttcaaagta atctccagta tatccaaagt acgctgattc
    34921 attactttaa tgtgtttgtg agtgaattag atacgaaact tgaaaccaat atccgcttta
    34981 attccgatca gttactagag actgatcctg aaacaaaagt aaaaaatgta ttggatcagg
    35041 tcaaagggtc acttctcacg attaatgagg ggcggtcgaa aatggggcta ccccccatgg
    35101 atggtggcga tcgtttacta gcaagtttga actttacgta tttagatacg ttggagaaat
    35161 atcaattaaa agaacaggaa ggagttacac cagttgaata atgaagaaga aaaggaaaaa
    35221 cggctgacag aagaagctga gctaacagcc gattctccca aagtagagaa agaaaatgaa
    35281 aaacaaccaa cagacggcaa aactatttca ggctatgcgt tgaaattcgg gcaaccgtca
    35341 aaagatttag gcggctttgt agaagtgatt acacccgaag cattaaaaga ggtggattta
    35401 tcaaatgtgt tcttattata tggacacgat tattcaaagc cactagctag tgtcaaagca
    35461 ggtacgttga aattgaatgt cgatgataca ggattacatt ttgaagcaga gctaaccgac
    35521 acgacctatt caaatgatgt gtatgagaat atctcaaaag gggttgttga ttctatgtcc
    35581 tttgggttcg tgcttggatt agattcattc gacaaaaaag aagatggcac aattgaacga
    35641 tcaatagata aaatcaaagc acttaatgaa attagtgtcg tgaccgttcc cgcttatgat
    35701 tcatcaaatg tccaagtaaa taagcgttct tacgaatcgt ttatgagtaa caaccaagca
    35761 aaacaaacaa acaatagctt agaatccact tctaaagcac aaaaggagag taataacatg
    35821 gaaaaaactt taatcgataa cgaaaaaaca gaattgcgtg ggtatgaaga atatatccgt
    35881 tcacaaggcg aagtgcgtga tggagtcact actgtaaatg cagcggcagt tgttcccgaa
    35941 gaagtaatcg gtgaagtctt tgatttgaaa cgttcaaatt ataacttagc tcaatatgca
    36001 acagtaaaaa cagtatcaaa tggacaaggt aaatatccag tagcaactaa ccaacaagca
    36061 gtgttagcaa caaaagctga acttgctgaa attggtgata ttgacgctga aatgtttact
    36121 tcagttgatt ataaagtaga aactcgtgct ggtaagattg ccttatcaaa tgaggttgtg
    36181 gaagattcag cagtgaatat tgtacaagag gtcaaagatc agttagcgaa attggtagaa
    36241 aacactgaca ataagcatat catggattta ttaaaaacat tcactaagaa aacggctgct
    36301 acgttggacg atttgaaaca actatacaat gtggcattag acccagcatt aaataaaatg
    36361 gtaattctaa accaaagcgg atattaccac ctagatacat tgaaagattc agatggacgt
    36421 tacattttac aacccgatgt gacagcacct agtggtaaat cattattcgg tatgccagta
    36481 gtattgattg cagatacatt gtttgccaat cctaaagctg gaacattccc tatgattatg
    36541 ggggatattg cacaatctat ctttgttgct cgtagaaatc aagtaacgac tcaatgggaa
    36601 aaattcgatt actactcaca aggacttgca gtgatcgttc gcaacgatta taagaaaatt
    36661 gatcaaaatg cttcagtgta tattgagttt acgccagttg taacaccaaa agtatagaaa
    36721 aatattgggc ggcggtttat cccactgcct ttttttcatt aggagagata aaatggtaat
    36781 tttggatagc ataaaaaaaa gtatgcggat cgatcacact attgatgatg actttattca
    36841 acaattgatt gatacagcag gcgaatatat aaaaagtgct attgatagta gcgcaacgga
    36901 taaagatatg gataattatc agcaatttga tttggcggtg tcattactta ctcaacattg
    36961 gtatttgaac cgtcaagaag ccagcagcga acggatacca gtaacggtac aagcattagt
    37021 acaacaaatg agaggtgctt attatgccaa tcattaagaa tgtaaatgaa ttgactgaga
    37081 gagtcaagtt taaaaagaca aaacgggtaa aagatgaaga tgggcagatg gtggatagtg
    37141 aagaaactgt atttgaatgt tgggctaatg tgcgttcaca aatgctaaaa gacgtgcttg
    37201 ctagtgtagg taccattctt gaaggaacgt tgacgtttat tattcgatac gatcaagatt
    37261 atgaactaac aaacgatatg aaagtagctt ggaaaaacaa gagttataaa attatttcaa
    37321 tcaatgaagg aacggcgttt aaagattata caacgatcat agctaaacag atttcttaga
    37381 atgattacac ttgtaaacgt tgtgggtatt tagtataatt aaggtagtaa atgaagggtt
    37441 agctgcctga attttgcaag acttagctag tcgaaatcta ttgttggact gaaaattgta
    37501 ggtgtggttg caaacatgct ggactaagaa agatgataga tgatgaacgt tcaattttaa
    37561 tacaggcatg ctaggactga ttggatggtt ttggcaagct gattgtgtag aaatcaaaga
    37621 acacgtctgt tgtggacgtg ttttttttgt tataattcaa aagaggtgat ttaatggaca
    37681 aagcagagtt tacaaatttt tattggaagt attatctaca tttagaaaat gagtttatta
    37741 ataccacaga ttttgtgatg ctcgatgaga ataatttcaa aacattctct attgaatatc
    37801 aaaaactact actagcgatt ggttcggagt gtgagattat tttcaaagaa ctttgcggat
    37861 ttgatagcag tagcaataaa agcataactg attttaaagc tgttattaaa tctagcgaat
    37921 taatgtgttt ggataatggt gttagggtta tgaattcttt aacattgact tcactaaaac
    37981 cttttggaga tgggtggcct gaagatacac cagattggtg gaaaatatat aacagagtaa
    38041 aacatggtcg ttcttcaaat tataaggaag caaatttgga aaatgtgttg tatgctttag
    38101 caagtctata tttattagag gaatatttgc ataagaaagt aatactagaa ggtgaagtag
    38161 actttataag tccagagtca aatctattta cgttatcttg ggaaagaaaa cattcgtcga
    38221 tgcaaaaagt gacgtttgaa aaagtggatt caaattatgt agctccactc attgatttta
    38281 aagaacaaga agaaatttaa aaacccccac ggcttattga agtttttgta tgccatattg
    38341 tatgccattt ggtttaaatc gcttgaaaaa tagtgataga taactctaat tcatttagtc
    38401 ataaacgctg ttttgataac ctttatagtt ctttgatatg ggtttctcat tcatggcgga
    38461 agaagaagaa tagaacaaaa gaatgaatta ataagatata aaaaaaggga ttgtgacaaa
    38521 cgtcttgtca caatcccttt ttccaaataa acgatgttca atcagctgcc cctcggcatt
    38581 cgctcgaaaa acggcgaaat atgaagaact attttgccat ttgtttctct aataatcagg
    38641 tcaaaacgtt gacttcacag tctcttcctt aaacggtgtt ctcctgccaa ctcctcggtc
    38701 acaagtcaca atattcaaca aacatgagaa gctgtttttt gaaattgttc cttgtgactc
    38761 ggagctgaac ggcaggctca cgacctcttt cttaaacggt gttcaaaagc ttgcatctgc
    38821 ggtaataagt tcaaccaaac gaaaattatg aggagctatt tttgtttggc tgttcttatt
    38881 acttgatgca ggacagcttt ttcacaacct cttttcgttt agcactaaat ttccttaaaa
    38941 agtagaaaag ctttcgaagc ctcgtttgtt tcttttactg tataataaaa gaaaagagta
    39001 acaatcgcta aaagatataa acaagagaaa ggaaatacaa gatgattggt ctgatttatt
    39061 ttgtggtgat cgttctggcg aacacagttg gcgctatttc cgggatgggt ggaggcgtgt
    39121 tgatcaaacc gattcttgat cttatcggcg cccattctgt tgcagggatt tctttttact
    39181 caacagttgc ggtattcacg atgtccattg tttcgactgt gcgacaagta tcaagcggga
    39241 aatcactgaa ttggcagatt gtcggttggg tatctagtgg agctgttgtt ggaggagtag
    39301 tcggcaacat tgtattcgaa gtttttttac agttatttga aaacgagaag catgtgcagc
    39361 tgatccaaat ttttttgacg gtattgacct tggtttttgc gttcttctac accaagcatc
    39421 atcagccaaa atttcatttg acgtcatgga cttggtacct tatatgtggg ggggttctgg
    39481 gctttttagc tagtttttta ggtattggtg gtggaccagt caatgtttct ttgttgatgc
    39541 tgatgtttgc attgccaata aaagaagcaa cactatattc tctatctacg attttctttt
    39601 ctcaactggc aaaattggta acgattgctt taacaagtag ctttatgcgc tttgatttat
    39661 ctatgttgtt ttatgttatc cccgctgctg ttattggagg tttgtgggga gcaagattta
    39721 gcagggtttt gtctccaaaa aaagtgacct ttatttttca agtaattgtc ctcgtggttc
    39781 ttttggtcaa ttgttacaat gcctttgtca tcttacaaac attaggagaa tctagactaa
    39841 cgcaagtcaa aatcactgaa acatattgtt ctaaatgaaa aaaagagtat actatgataa
    39901 aaaaattcat tttaaaaaat cagaaattgg ctggtgattt ggatgttacg ggaaatgcgt
    39961 ttagaagatg cagaagcact acgtgaaatc aatgcggatc aattagggta tgatatacca
    40021 ttaaccgtta cggtgagaca aatgaagaaa ctgctgaagg agccagagaa aaattttttc
    40081 ttggtttatg aagatcctac ttctaaaaaa gcagctggct atgtacaagc ggagtcctat
    40141 gaatcgattt ttagcgatcc aatgttcaat attatggcac ttgctgtgtc taaatatgct
    40201 gaaaaaagag gcatcggaaa ggctttgatg actggcgtag aagaagaagc gaaaaaacga
    40261 ggaataacga caataaggct taattctgca gaatacagag tagaagcaca ccaattttat
    40321 gaacacatcg gttatcattc cgataaaatg caaaaaagat ttttgaaaat cctgtaaatc
    40381 tttatcaaaa aaatacccga tcaccaagcc gatacttgat gatcaggtat ttttgttttt
    40441 ttgactaaga aagtaattgc atcaagaaac cagagatgat caaaacgatg gcaccaccaa
    40501 gtcgattgcc catttgagca aaagcaataa gttccatccg attagctgca gataagacgg
    40561 ctacatttcc tgttccgccc atcgagttgt tgcataagcc agcagtaata gttgattcaa
    40621 ttggatataa accaaacaaa cgaccgacaa atcctgaaac aactgaaatc gcgataacac
    40681 ttgtcagaca taagacaaca aattgccatg tcaaagcaga agctaataca ttcagattca
    40741 gcaacgcaat accgataccg gcaagaacag ctgctgtcaa gtttttgaca atcaagttat
    40801 tgaacatgat agctgcatct tcataatact ctggtaatag gttggcgatt ttacagatga
    40861 caacgataat aatcataaat gcgtaagcat ggactttagg aacaaaatag ttaccaattt
    40921 gtcctaagat gaagaaagtc aatgatacca tcaaaccaac acctaactgt ggaatggaag
    40981 gtttcacagt tcgaggtttt ccatcgccaa gatcgccttt ttccattaat ttaccattgc
    41041 cgttgaattt tggcattgat tgtccagcac gagcaactaa tgctgcaccg atgatagcta
    41101 agacatttgt cattgctgtc gcaggaatca ggcgggaaat gatagaagaa gcatccgtac
    41161 ctaaaacatt tgcataaatc gttgataaag gaacggctcc ggctccaaca ccaccagcca
    41221 tcgcaggtaa tgagatgtat aaaacggaat ttgcaaaacc atttccgata agcatgccca
    41281 cgagtcctac ggcaaaaaag gagacgacca ttgaaataag tgcaacggga ataaaacgaa
    41341 cagaagcttt catcaataga ttacggttca taccaaggat gctaccagta atcaaggcag
    41401 caatataaaa gtcccaaaag cccatattgc tgacaaagtt ttctgtggat ttcactacat
    41461 attcaggtaa gatcccaaat gtagcaatcg cagcagaagc gaagatcgca aaaacggaac
    41521 caccacccaa ataacttttg acgataggga tttttgtccc gataaaatga aataaattac
    41581 cgaaaataac caaaactgcg attggtccaa tcatattcgt cggtaatttc cctaaagcca
    41641 ttgcaatgat caggacaagg accatgatca aataaagtgg caaacttacg ccggtgattt
    41701 ttgtggacca aaaaccttct tttttctttt cctcaactgc agttgcagtt gttgtttttt
    41761 gtgccatttt tacagatcct ttcttattct gtatcatatg aaaaaagcca aagaaaagcg
    41821 acaaaagagc aggagttggc tggccgctgt tttgccgcag tcgctttttt ctttttagac
    41881 gtcatacaaa gtttctgtat gttcttttac tataacgatc ttaatcttct aaagatttat
    41941 attcaggaac ccatttagca gattcaactg cttctttgat atccgtgatt tcttcacgat
    42001 tcaagttttg tgcgacaact gattttgcga cagtttcagc aatcgtttga gaaaattcag
    42061 tgatttttgc tactggaggc aagatagctg ctcctggttt tgttacatca acgattccgc
    42121 ctaatgctcg actagcttga gaaatgattt cagcatttac tcgtgtagct gttgaagcaa
    42181 tcaaaccaag tcctaaacct gggtacatca aagcattatt tgcttgaccg atttggtaag
    42241 ttacaccatt atattcaaca tcagcagcag ggatacctgt tccaactaat gcttttccgt
    42301 ccgtccattc tattaaatct tttgcttttg cttctgccaa ttttgttgga ttagacaaag
    42361 gcatgatgat cggacgtggt gtatgagcag ccatttcttt cacgatttct tcagtgaatg
    42421 ctccaggttg ggtagaagta ccaatcatga ttgtcggatg gatcgctttt acaactgctt
    42481 ctaagtttgt caattcatca gcattagtga aatctgagcg tttgcgagcg aatgggattt
    42541 gaccaggagt caatccttct gtatcttcaa acaataaacc ttgtttatct acttgataga
    42601 aatgttggcg tgcttcttct tcaggtacac cttgacggat catctcatct aaaaggatgt
    42661 ttgcgatacc cacaccagca gtaccagcac caaatgtcaa aattatttga tctttcaatt
    42721 gttcaccgga tatattcaat ccgcctaata cacctgctag gacaacaatt cctgtacctt
    42781 ggatatcgtc gttgaaagta gtgatttgat cttcgtattt ttctaagatc gctgcagcat
    42841 ttcctcgtcc aaaatcttcc caatgcaata acaattctgg gaataattcg gtagctgatt
    42901 gaacgaattg atcgatgaat tcatagtaag tttcgccttc tacacgagca tgacgattgc
    42961 ctaagtataa gggattattc aataattctt cattattagt accagcgtcg atcgatacag
    43021 gcaaaacttg tgctggatta ataccagcag cagcagtata gaccatcaat ttgccgatag
    43081 cgatgtcaac accgttcaca ccccagtcgc ccatacctaa gattccttct gcatcagtca
    43141 caacaatcaa acgaatgtct cgtccatctg ccgcgttctt caaacttgct ttgatgtttt
    43201 ctggttcgtc gattgaaaga aatgcagcat cttgcggttt caagaaaatt tcgttgtatt
    43261 gttcgattga atccgcaacg acaggatcat aaacgacagg catgaattca actaaatgtt
    43321 cgcccatcaa tttataaaac aatgtccgat tcgtattgaa tagattcatt aagaagatac
    43381 gtttttccaa atctgtttgt ttgcttaagt attgaccata agcttgaaca gattgttgtt
    43441 ccagtgtttg gacagtactt ggaagcatac cagtgattcc atattttgcc cgttcttctt
    43501 ttgtaaaagc tgttccttta tttagaaaag gattatttaa taagtttaac cctgtaagca
    43561 tgaatgattc ctcctaagtt ttaatacaaa cgaagtatag aagtcagatg atgatatagt
    43621 caaaaagagc aggtatgata aattttattt atatgtaata tagccaaaag aaatcaaaat
    43681 agcagtattt gttcttttta tatcgacaat ccttgcttga atactatgcg tatctcttat
    43741 atgctagaga aagaaaagta gaagaataag ggatagatgg aatggataaa taggatttct
    43801 gaggaaaaaa gcacatgata gcgttgatag gagtcaccta tgtcaggtga taaaaataca
    43861 taagtagaaa attaagagga ggaagagaaa atgaaagaag ttcaattgat tagaaaaagc
    43921 gaactatcag aaggcggttg caatgcatgt ggcgtagtag aagcgacaag ctatacatta
    43981 aaattagatt ccaatcaagc aataatctct gaactgacag taggcggtct tgtggacagt
    44041 ctggcgcttg ctgaaggttt tactggagaa gatatttatg agatgttttc agaagtccgt
    44101 cagttaaaaa aaggagaaaa atgcatagag gttcatcatg agagcccgaa tgtgaggttc
    44161 aaacgtggtg ataatgagat gatcttcaag aatcatgtgt ctgatcacac tgaactatat
    44221 gaaatcgtga atcaaatact gtctgggatt tttgaattag gaccttatga gttcaaggaa
    44281 gaaaacggta atccaaaatt aaatgaagaa tggcaagaaa cgattgaaac acaaagaaac
    44341 aatccacact tatttcaata gtcttccaca gtatttcgta aaaatgttga tgaaaaagaa
    44401 acaccgtgaa tcagaggtcg tgaaaaacct gccctgcatc aagtaataag aacagccaaa
    44461 caaaaatagc tcctcctatt tttcgtttgg ttgggcttat taccgcagat gcaagttttt
    44521 gaacaccgtt taaggaagag actgtgaagt caacgttctg acctgagtat tagagagaca
    44581 aatggcaaaa tagttcctca tattttgcca ttttttgagc taataccgag ggtcagctga
    44641 ttgaacaccg ttttatcgag aggttgtgaa aaagtcgctt agtttcgagt agtaagaaaa
    44701 attttgtgaa aatggctttc cacatttttg cataaatttg acttaatacc gagaaaatgg
    44761 cttttgaaca ccgtttattc aaaaaaaggg actttgacac tacttttgtc aaagtcccat
    44821 cggtttttta tctattttta ttacaatcat ttcttccaga gtagtgacat ctggaatggc
    44881 tgaaatgtaa acagattatt tgcctgtatc aatgtcgaag agtaatataa aaagtgtaaa
    44941 cgctatcata ttgttcatca ttcaaatttt atagagagaa ggcattgaga tggaaaaaac
    45001 atatcaagca ggtacaaatg aaggaatagt agattttatc aatatggaag atttagaaat
    45061 cgcggcttca caagtgattc cagctggtgg ttatggttac atcagcagtg gtgctggcga
    45121 cttatttact tatcaagaaa atgaacgggc attcaatcat cgtttgatta ttcctcatgt
    45181 attaagagat gtagaattac ccgatacaac tacacatttt gacgaagaaa tgctgactgc
    45241 accaatcatc atggcaccag ttgctgctca tggattagct catgtgaagg cggagaaagc
    45301 ttctgcaaaa ggtgtagcag attttgggac gatctataca gcaagttctt acgcttcttg
    45361 tactttagaa gagataagag aagcaggcgg ggagaaagca ccgcaatggt ttcaatttta
    45421 tatgagcaaa gataatggaa tcaatttgga tattcttgaa gtggccaagc gtaatggagc
    45481 aaaagcaatc gtattgacag cggatgcaac agttggcgga aaccgtgaaa cagaccgcag
    45541 aaacgggttt accttcccgc tgccaatgcc gatcgttcag gcttatcaat caggagtagg
    45601 ccaaacgatg gatgctgtat ataaatcttc caaacaaaaa cttagtccaa aagatgtaga
    45661 atttatcgct gctcattctg atttgccagt ctacgtgaaa ggtgttcaat cagaagaaga
    45721 tgtctatcga tcattagaat ctggtgctgg tggaatttgg gtatctaacc atggtggccg
    45781 tcaattagat ggggggcctg ctgcgtttga ttcgttgcaa tatgtggcag aagcagtaga
    45841 taaacgtgta ccaatcgtgt ttgacagcgg tgtacgacgt ggacaacatg ttttcaaagc
    45901 aatcgcatca ggtgccgatc ttgttgctat tggcagaccc gttatttatg gattgtcttt
    45961 aggaggaagt acaggagtcc atcaagtgtt tgatttcttt aaaacagaat tggaaatggt
    46021 catgcaatta gctggaacac aaacagtaga agatatcaaa aaaataaaat tgcgtgagaa
    46081 tcgttttatt taagaaataa atgacgaaaa aaataggagt gcggcagatg atgccgtact
    46141 cctattttta tagttcaagg atgtcactaa tagaataatt tgaaacgaaa aaataaaatt
    46201 gaaatattgt ttcatactta ataaaaaagg aagaatattc atgtaaacga ttttattgtt
    46261 tttttctctt ttatacaaaa agggtcataa tttcaagtaa gcggatgaat tcatgaggat
    46321 tttttgcata ctgtctctac tatacttagg tcactaagaa aaaggagtga tttattatga
    46381 aaaagaacat gattgggaca ttattacttt caacacttct tctaggcggc ttggcaacac
    46441 cagcttttgc tgagggtcaa gcgacttcaa aaggagatat tacctttact gaaccaacaa
    46501 ataccgttga gcctcttaac cctactgatc cttcaaaacc agtagagcca gcagatccgg
    46561 aaaatccagc aactggccag acaggttctt taacattgga tgtagttcct gaattgccat
    46621 ttggtacaca cgagattgaa agcggaacaa aaacgtatca agtagacgct tcaaaaaacg
    46681 atacacctta tctccaagta tcagatcgtc gaggtgtagg tgcagatggc caagcacaag
    46741 ggtggaacgt gacagtttcg gtttcagatt ttgtaaacgg ttcacaagtt ttgcaaggcg
    46801 ctgaattaga ttttggaaca tccactgtta aaagtacgtc agataacgaa tccactggac
    46861 caactagtca aactgtaact gggttgagta aagcaagtgc agcgacacca atatttacag
    46921 cagcaaaaga tcaaggtctg ggaacatggc tttctgttta tgatccagca aatatcacac
    46981 tgaaagtgcc gaaagcagca gctggaacat tcacggctga tttgacttgg aacctcgtgg
    47041 ctggcccagt agcatagagt atgaaataaa ttcaacaaac tgcggtgaaa atactatagg
    47101 tgaaggattt tttaccgcag ttgttgttga aaggatgtgg tggacaatga atcaaagtaa
    47161 acgactgttt gtttcgtttt tttctatttt aagtctattt ttcatttttc cgtcaatcag
    47221 ccaagcaaag gattcagcag gagactttgg aatcaaaccg gtatttccag agaaccaaat
    47281 agataaagca atcggttatt ttgatttatt agtggcaccg gaacaaaatc agacactaga
    47341 agtaattatc agcaattctt cagatgaaga acgaacattt gaggtctctg tcaatccggc
    47401 ggtaacgagt gatggtggaa cgatcgatta tagtcaaaaa aacccaacgt tagatgagac
    47461 attgccgttt gatgtccgtg acgttttgct cattgcgaaa aaggaaatca atgtatcagc
    47521 acatgcagaa acaactatac ctatagaagt gaaaatccca gcaaaaagct ttaagggacg
    47581 tgtattagcg ggtattcatg tttcacctaa agaagaagct gaaacagaaa atgctacaga
    47641 aggagcacaa atcaaaaatc gtattgctta taatctcgca gtcgttttac aagaaagtca
    47701 agagacgata gaaccggatc tgaaactttt atcaggagat ttggacgagg tcaacgcaaa
    47761 gccaactgtt cagcttcgtt tccaaaatcc tcagcctagg attatcagca atttgatatt
    47821 tacgagcaag atcttttatg aaaatcagct ttatattgaa aatacgtcta atgaattttt
    47881 agttgcacca aattcgaatt ttcacttgaa tcttgattta gctggtgata aagcaaaagc
    47941 cggcgattac cgcgcagaaa tcatagcaaa atcaggcgac agtaatgaat ggcgatttac
    48001 acaaaacttt acgatcaaaa aagaaaaagc acaaaaagta aatgaaaatt ccgtttttgc
    48061 agtacaagaa caatctttcc catggcttta tgcaggattg gttgctgcag ttctagtgtt
    48121 atggttgatt ttgctgtttt tgtgggtcca caagaaaaag aaaaaaggag aaacaacatg
    48181 atgaggtgat ttcgttgaaa acatcgatct tattgggagg gattattgca agtttgctgt
    48241 tcttcagctg gcaagagcca gtccaagcag ataccaaaag ttcaggtacg attacatttt
    48301 atgatctaag tccagttccg catccaagtg gttcagtcaa tggcgcatca aaacagcaga
    48361 cacagctacc gatttataaa gaatctaatc aacatggcgt attcccggag acgaatgaag
    48421 aaaagatccg ttttctttat ttgatcattg gtatagaatt atggcttctt gcgtggttgt
    48481 tgttatggag aagaaaggaa aaggaggatg aacatgttgc tacaaaataa attttcattt
    48541 tttcgctcct tcttttttac ttcgcttttt gttttaagta tatttatctt ttcaccttcg
    48601 gcagaagctg ttggagcaac gcctcctgcc atttcttatg atccatacac gtatgaaaat
    48661 atcgtacctc caaatggtgg acgtagtgca gtcaatggcg ggaagcttgt ccaactaact
    48721 ggggctaacc aattgcctaa attgactgct acttatttga acgatggttc aaatgatcct
    48781 tggaaaggtg gcacggtccg ttttcattgg gaaagccatg tgaaactaac aaatgtactt
    48841 gatttggtga atatcactgc acaaggattt gcatttgtgg cgatcatcaa tttgccggaa
    48901 catgtatcaa gcagtgatgt attaaaagca attgactgga acaacgccta cttgtatatt
    48961 gccggtgccc ccatcaaggt tactagcggt agtttattat cagcaggaag ccataccttg
    49021 cgttttggga tggggtcgtg ggatacaaat actctattgg cagatattat tgctattatt
    49081 acgcgaggta tcccgcttca atttgatgtt acagctaatg tcgcgaagat gacagaaaac
    49141 ggagataaat atgatacgag tccaaacaaa attttgacca agggtaaatt acaaccttct
    49201 atgtctaaaa aggccgtttt ttctgttgat ttttatgatt cgaataatat tatccaagat
    49261 cgtatgttca attcgatttt agctccagct gcaggtagat tttatcctaa attaactggc
    49321 ggaaacttga atccaggagc atatgcattt tctgcaagtg cagagataaa tacgtggaat
    49381 agttacatct caacaagtga ttcaacagga aaatataata catttgctga taccacagaa
    49441 tacgtggatg gaaataacca gaaccttcca ggctctacca atagtcggac attgacgatg
    49501 gggctgactg aaggacgttt tgatcagttg ccatttagtc gctttgatcg cgtagtcaac
    49561 tattttacag gaaaaaacgt tacacaagga gcaatactga ctcatactcc agcaagcaca
    49621 agtggattga atcagacagc caatatcgtg tacagtggga aagatgcgca aggcggattg
    49681 ctttctcctg ttgctttaaa ggtattggag cagtacaagc tagacggaac ggttttacca
    49741 acaaacttaa cagccgatag tcagtgggga aagctccttt cttctgcatc gtaccaagtc
    49801 acggccaatt ggtcagcaac tgaactaaaa aagggttcga tccattacag gctttattcg
    49861 aaaggaaccc aaaaattagc gacaggatgg acagatcaac ttttccaaac gatccaatca
    49921 aataacgggg gtgtaaatac agctacttct acactacctg cattggcttc agggcaatat
    49981 tattttgatt atcgcttggt ggacgatgta cttactaaca tgtatccgtc ttttgcgtac
    50041 aaatggcagt ctgaacaagc tggaatcacc actcttcctc aaataacagt ggctaatttt
    50101 ccatctgtga gtgcagatag tcagctaaaa aaccttagca gacaacctga gacaggagat
    50161 cccctgtctg ctctatcagg agatacgatt caagaaaatg tgacattcac gttaacaaaa
    50221 tctggggatg cgataaccga caaaaaaatc acgatctcac ttcctgaaaa tactacttat
    50281 atcaatggtt ccttaaaatt aaatggtaca actatcgcag ataccggcat tcaacaagga
    50341 gtttctgtcc cagcagatct attgagcaaa ataggagata ccattcatct tacttacaac
    50401 tatcaattaa atactgtaga tacttctgta caatccgtca gcatactgac aaaggcagct
    50461 gtactttcca gcaatattac attagcagat ggtgctaagc ttcctaaccc agttgtccaa
    50521 acatctgcta aaacaattct tgtccccaaa caagaattaa cattagttaa tgtaccagat
    50581 gattttacat ttggtaacga tctccccaaa ccgttgaaga caagttatta tgaagcaaaa
    50641 ggcgattttt cttttgatgt gcgggatact cggcttccaa gcacgtctcc ttggcaactg
    50701 acagggacat tgacttcttt atttaagaat gatcaaggtc aagaattaag cggaacaaaa
    50761 ttatacttca atcattctgg atcaaaacaa ttgattcagc aaggtcaaaa cacgttgatt
    50821 tatgagagtg atggaacagc taaaggagag gttctcgttg actttcccga taccgatggt
    50881 ttactcttag aggtaaatag cagtacgaat gctcaacctg gcgcaacgta tcaaggcatg
    50941 gtcacatggg aactgacagc tgggccaacc agctaagtga ttagaatttg tatggatctg
    51001 tgataactgt cacagatcct ctttttcaag gatgagaagg aaacttctgc tgttaaaatc
    51061 agaaatgctt ggaggagtgg acttggaact tttcagtttg cttgaaaaaa atgaacaacg
    51121 gcaaatcaaa cttttccaac ttttattaga ggaaaaagga gagatttccg ttaataacgt
    51181 acttacccgc ttatcagttg atcgggctac cttgaaagaa gatctgtttt atttacaagc
    51241 taacttggaa aatatcaaac aattggaaat tgttatccaa gaagggaata ttttattaat
    51301 cagacatgga aatatagcag cagtcgatgt ttattatcat tgctacttgc gctattctac
    51361 aaaatatcag atacttcttt atctgttgga aaatggctca tttgatcggc agaaacttgt
    51421 catggaactt aatatcagtt cggctacttt gtctcgcaga gtgaaggaat taaatgattc
    51481 tttaaatgag tttcatctga aaataaaaag cgggcggctg accggtccag aaagtcaaat
    51541 ttgttatttt tatttccaat tattttggtt tggacgtcct tatcttgaaa acaaaaaaga
    51601 atacagtgat ttatcaggaa acactttttt agatctgctg caaaaagagt ttagttttac
    51661 tattacagaa gaaggacgat tgaaatttga aatatggctt tccattatga agaagcgaat
    51721 gcgctgtacg aaaaaatcca aaccagatta tagcaatctt cctgttggat tgtttcaaac
    51781 gacacaattt ttattggacc tccatacatt tttgacccgt tacttctttc aatatgcctt
    51841 tccttggaat caaaatgaaa cgttggtttt ttatcttttc atgatcagta actttacatt
    51901 agatacacat aactcgcatg tccaggagtt tttgataagc gaaaaataca aagacgacgt
    51961 agtagctcaa ttgaatcgaa cgtttaaaca atcgatagaa gaatatttct ctttttatgt
    52021 ttttccagaa gagatttcgc aaaagattgc gttgacagtg atgcaaaatc acgctcattt
    52081 tgcctatttt agaggatgga tgaatatttt tggccaagaa ggattaaaac agcggttaac
    52141 tgaagtagaa gataaacaat tcctggtttt atgtgaaaga ttggtcagac aaacatttgc
    52201 tattgttgat tttactgaag tagacgagga aaatgcccgc tttgaattat ttgctcgcta
    52261 tgcatctatt ttgcggacgc tgatcaagca gttagaatta cgtctgcaaa ttgcttatga
    52321 tcttccttat gaaaggctaa tggcggatat cgtgaaagaa atcatccagg aacaattgct
    52381 gaatacgatc aaatatgatt tagtcgaata cgagaaagaa aagcagtatg atatcatttt
    52441 gactagccaa ttgaaagagt acccgtcaca gaagtccgct aaagtttttg tattcactag
    52501 caacgaatat aattatgatt tcccctattt gaaccaattt ttaaaagaat gttatttaga
    52561 aaaattgaat ttaaggatga ataaaacatg aaaatcgtga tcattggtgc ttcccatgca
    52621 ggcatcacag ctgccctaaa tctaagaaaa cttcaaccga aagcagaagt tttactgatc
    52681 gatgaagatc ataaagatgg actaggctat gtttcaaatg gaatcaacct ttatttaaaa
    52741 ggaaagatac gtagtttagc tgaagttgcc cataacatgc ggactcttca agaaagtggg
    52801 gcaaaactga tcaccgaatg gagagtaact gaacttgatc cagacaaaca tcagctcatc
    52861 ctcgcatcca aagaaggaaa aaacgagacc ataacctatg ataaattaat cgtagcaaca
    52921 ggttcctctc ctgtcacctt gtataaacaa attgaagctg aaaatgtcta cacctataaa
    52981 aatctagtgc aatctaagca agtacttgcc gctttaaaag aagcaaaaga agtagtgatc
    53041 ttcggtgctg gttatattgg attggaatta gcagatgctt tgagaaataa aggatacatt
    53101 attcatctag ttgattatat gccgaatgtt ttatcaagat atttcgataa ggatatgatc
    53161 aacagttttc aaaatcagct gcaaactaag caaatcaatt tttatccaaa tgaattcttg
    53221 atcgattgga aaaaatcaga agagaaagta gtatccgtac aacttctatc tcaagcaata
    53281 aaggcagata tggtcatttt ttctgcccaa actcgtccta atacgacatt gttaaaagaa
    53341 aaagtggctt tgtatgagga tgagactgtg atagtcaatg aatatctgca gacaagtgat
    53401 ccggacatct atgcgattgg agatatcgtc ccagtcagtt ttgacaaaaa taaacggcat
    53461 ctctttttac ctttagttac tcgagctgta catatggcaa gagcagtagc gctaactttg
    53521 agtggtcagc caaccgctta cgacctcaga caaaagataa cagcagcagt cattatagac
    53581 tactttttag gaactgtagg gctgacagaa gatgaagcgc cattcttgga acaaaatacc
    53641 ggttcgtgtt caggagaatt tgatctattt ccacaatacg atgaagaaaa caaaacagta
    53701 aatgcaaagc tgatctacca tccggataca ttagaaataa ttggcggaca gctgataagc
    53761 caagaattct tattatcaga tttgaacctg cttgcggata tcgtgaaaca caaaactacg
    53821 attccacagc tagcagttga ggattttgga tttctgtctg aacacacctc tcgttttcac
    53881 tacctcaatg agttagcttt taaagtacta gctaagagag caaatagcaa tagagtagat
    53941 aaaagactgt gagaaatatc acggtctttt attgtgtggg gatataataa atattaatca
    54001 atcgagaata aaaaattcat ataatgaaat agcggaagaa ttttttgagc ataatattcg
    54061 ccaaaaattt atcaagtgat aaaattgttg tataaaatga ttatttcagg aggaggagtt
    54121 aaatgttttt agcattaaat gaaattatgc attcaaagtt acgttatgcg ttagttgcag
    54181 gggtgatgtt tttgatcgcc tacctggtat tttttttgac tgggttagct tatggcttag
    54241 ctcaagataa tcgaacagca gtcgacaagt gggaggcaga ttcgattgtg ctttcgaaag
    54301 atgcaaattc aaatctaggg atgtccatga ttactaagaa gatagcagaa gaagtcgaag
    54361 gtgggaaagt ggcgtatctt gcccagacac ctggagtcgt gactagtaaa gacagtacag
    54421 aagaaggaaa aatcaatgtt agcttcttcg gtatcgataa aaatcaattc atcatgccca
    54481 atcttgttga aggaaaagct tttgataacg atgatgaggc agtaggcgat attagtttga
    54541 aagaagaata tggtctagcc gtaggagata cagttaagtt atctggtagt gacaagacgt
    54601 ttaaactaac tggctttacg gatcatgcca aattcaatgt ctcaccagtt ctctatacaa
    54661 ccatcaatgc ttaccaagag atccgcttcg aaaaagaaga tacaagtgaa aatgcacgga
    54721 ttaacgcaat agttgtcaga ggtaaaatca gtaatttacc tgaagattta gaacagatca
    54781 aaatttctaa attcatcaat gaattacctg gatataatgc gcaagtattg acttttggat
    54841 ttatgatcgg atttttgatc gttattgcgg ctattgtgat cgggattttc atttatgtac
    54901 tgacgatgca aaagattaat atctttggtg taatgaaagc acaagggatc acaggaggat
    54961 ttattgcgcg ttctgtagtg gcacaaacat tcattttatc atttgttggt attcttcttg
    55021 gtctattagg aacagtggga acatcccttg ttctacctga tgcggttcca ttccaaagca
    55081 attggctgtt ttttggcgtc attagcttgt tgatgctggt agtagctgtg ttaggcgcac
    55141 tattttctgt tcggacaatc gtaaaaatcg atccgttgaa ggcaattgga taagaaggag
    55201 gaagagcatg aaagcaatag aatttaaaga agtagaaaaa agtttccaag atggcgacca
    55261 agtagttaaa gcattgaaag aaacaaccat gagtatcgat aaaggggaat ttgttgcaat
    55321 catcggtcct tctggttcag gtaaaagtac ttttttgact ttggcaggcg gattgcagac
    55381 gcctagcagt ggctctgtat ttatcaatga tcaagaattc agtaatcaaa aagaaagtga
    55441 acgcgttaaa ctacgtttta aagaaattgg ctttattttg caagcttcca atctggttcc
    55501 ttttctgaca gtaaaaaagc agttattatt agtagataag atcaaacatg aacatcgtca
    55561 aaaagaagca aaagaattat ttgagcagct tggcgtggat aagttgatca acaagtatcc
    55621 agaagaacta tctggtggag aacggcaaag ggtcgcaatc gctcgtgcat tgtacaatga
    55681 tccgtccatt attctagcag atgaaccaac tgctagtttg gattcagaaa aggcacgaga
    55741 agtagtcgat atcttggcaa aagaatcaaa agacaaaaat aaagcaacga tcatggttac
    55801 tcacgataca cggctgattg acaaatgcga tagaatattt atgatggaag atggtgtatt
    55861 gaaagaaaaa gaataaccaa aaagcaggtg gaaaaatggt ccatcgatac aacaaagata
    55921 cacagcaaaa aattttgaaa gaagcgactg acttgtttat gtccaaggga tatctcggca
    55981 cttcaacaag agagatcgca caaaaagttg ggatcaccca acccaatctc tatcattatt
    56041 tcggtgataa agaaaaacta tatacggcag ttttagaaaa ccacttaaaa gatgttggaa
    56101 aagctttgag agaaatcgtt caaacaagcg aaacgggatt tcaagtaacc ttgacaaaaa
    56161 tggcgcagtt tttgattgag acacatctgg tcgatttgtt tctgatgctt cacgatcttg
    56221 aaagcaatct ttcaaaggaa acaagagatc atcttttctt tctatggaag aaaaattatc
    56281 gtgaaccttt tgaagaaatc ttttcagcaa accaatctgt gctaagaaat gggatttcaa
    56341 aagaaatcgc agcaaggcat tttttcttag tgttagcacc ttacatcact cggtcgaaaa
    56401 gacctgtgga agaaccgcta aatgtggcgc aattgatcga tttatatttg aatggtgtat
    56461 taggagaagc gtaaagctgt tatataggga gaaaaatagt taggtgaaga agcaagatat
    56521 gacgaagatc gttatatctt gtttttttta tataggtagt ttttcataaa tacaaatttg
    56581 ttattctctc atgattatca gggtatattt ttatttatta tgtcggtgtt ccaggaagtg
    56641 ttttaattta ataacgaaga aattaattgt ttgtagaatg aaggaaacta tttattgggt
    56701 agatgaatca ccacgaatag tcaaaaggag atttcaggat atgccaaaaa tgaaaaaaat
    56761 cattttagca gtaatgttat tttctacggt tatatctttt acagcccctt ttttgcgtac
    56821 ttaagctgat tttaagtttt gacccttagt ctggatctac gaggtgagag tcaagaatga
    56881 aaaaaataat tggagctttt gtatttgcaa tcattatcat tattatctgt tttcaaatag
    56941 atgtttttgg tcaaaaaaag atagttggac aaacggtcag cagtacgaac agtacggtta
    57001 caaagacaaa ggaatcattt gatgatacag aacaagagac attaatcaaa atcggaaaaa
    57061 atgaccgtac actatataca gatgactcgc taactacccc acttgcaact ataaacggcg
    57121 gagagctggc ggagtttctt tctgaaacaa aaaatgctta tcagatcaag acaaatgatg
    57181 gctatactgg atatttagcc ctcgaagatg gaaccaaagt cacaaagaat atacaaacaa
    57241 aaccggaaga gctatctgat gcagtgattg tattagatcc tgggcatggc ggaaatgata
    57301 ctggggcatt aagcaatgat gaacaaacag aagaaaaaga tataacatta agtacagcca
    57361 taaaagtaaa aaaggcgcta gaggatgctg gagcaacggt ttatttgacc catactacag
    57421 atgaattagt acagcttgga gatatatgcg actacagtga agaaaaaaag gcagatgtct
    57481 ttatcagttt acacgcagac tctacggaat atgcgaatga agcaactgga atcacgacat
    57541 attattacta tggacaagag gaaacattag cacagacaat tgctgactcc ttcactgatc
    57601 tgcctctgga ttcaagagga atctccactg ggaactatca agttcttcga gaaaatcttc
    57661 aaccttctat tttaatcgag atgggttata tgaataatga tagtgattta aaggaattag
    57721 taacagacag ttatcagcag cagattgctg caagtttgac acaagcattg accacttatt
    57781 ttcagtaata aataagccca gccaaacaaa aatagctcct catatttttc gtttggccgg
    57841 gcttattatc gcagatgcaa gcttttgaac accgtttaag gaagaggttg tgagcctgcc
    57901 gtttaactcc gcgtcacaag gagcaatttc aaaaaacagc ttctcatgtt tgatgactat
    57961 tgtgacttgt gaccgaggag ttggcatgag aacaccgttt attcggaaca agggactgtg
    58021 acatgacttt tgtcacagtt ccattatttt tttagcagct tcaaagcttt ttctgtattg
    58081 gcaaaatgaa gtttggcata tttttcaagc ataggcatgc cgcctttctc caatagtttt
    58141 gccgctactt ggtcagattt cgttccagct cctgatggaa gggtgattcc agcttcagct
    58201 gatgctttgt gtaactcttc caaaaagctg gcacgactga tgatagaagc agcagcaaca
    58261 gctaaatgat attgttctcc tttagtaacg aagtacagtt tttcttgtaa ttgatttttt
    58321 tctaaacgcg catatttttt aaaatttgct tccggcgtaa actgatcgat caaaatcgct
    58381 tctggttttt ctggctcgat tttttttagc agcaaatgga tcgcttgatt gtgcaaagcg
    58441 actttcatcc gaacggcatt gtattttggt tggatctcat tgtatttttc tggagataag
    58501 acaagcagtt tataggggat ggtttttttt aagatgtcag caagctggat gatttggcta
    58561 tcttttaact cttttgaatc tctaacacca agtttacgta attctgcaag ctgatcacgt
    58621 ttcacataag cagcacatac tgttagcgga ccaaaatagc tgccatttcc gacctcatca
    58681 ctacctaaaa cggataattg actgatattt tttggcaaag aagaggctgt ttttgctggc
    58741 ttggcttgtt tatcctgtgc ctccccccat ttatcagctt ctattgctgc attcgtacct
    58801 tgaaacatca cttttccgga tgtataagcg gtaatggtcg tcccgtcttt ttttgcagca
    58861 aagctagtat aaggaatctg tttatttaac aaataagagc gatagtatgc tttcatttga
    58921 ctaagttggt cgtttgttgc tttgataatg acgttgctca taaaattctc ctcgttttta
    58981 tacataaaac tataccgcaa ctcacgactt ttcgttttct aagagattgc gagacatagc
    59041 atttttttaa agtttatcat ataatagtta agtatgtgaa aaatatttgt ggagaacggt
    59101 gaaagaacca acttcatggt acactaaata aaactttcat caaataggag gaaatgattc
    59161 gtatggcgca cgaaaaaaca cgctacaaag cagtgattgc caaccaaaca tatactatta
    59221 tcggacggga aaccaagcat catatggata tcgtaacgaa gctgatcaat gaacagttag
    59281 cagaattgaa acaattatca ccacaaatgg ataatgaaca agcagcaatc ttgatggctg
    59341 tcaatgcgct ttcggatcaa ttgaagaaac aagaaagaat cttggagctg gaagaagaaa
    59401 cagcagaatt aaagaaaaaa atgatcaaat ttacagagct tgaaaatcgt gtgaaacgca
    59461 ttgaagcaat cgagaacgaa gctcgggaag tattgaaaga aaatggtcaa gcagatcata
    59521 ccattaaaaa tcatgtggaa gcacaacaga ttttaaacga gaaacgaaaa ggacaaatta
    59581 aacaaaaatc ttctaattaa gatcctttta tcaaaataag aaaaatttaa aaaagttaga
    59641 agagaaagga acgtagcatg ctgagtttgc tgattttatt tttattgcta attgcgtttt
    59701 tttctggagc acgtcgcggg tttgctttgc aaatcatatt cgcgattgga tatgtattgt
    59761 catttattgc tgcccagcat ttttacaaac cattagcaag tcatttggaa ttatacattc
    59821 catacccagc tgtcacccca acatcaaagt tagcattttt tgatcaggta tttgcttttc
    59881 acctagatga agctttttat gcaggaactg cttttctgat tattttgcta attggctggc
    59941 tgcttacccg atttgtgggg gtttttgtcc atggattgac gtatgtgccg atcttgagac
    60001 aggtagactg gattgcagga ggcatcctgt cactaatcat ggcttacgtt actatatttt
    60061 tgattttgca gttacttgcc tttgttccat tagatgtggt ccaaaatcaa ttcggcgagc
    60121 atagtttcgc tcgttttatc gttgagagaa cgccatttct taccaacaag atgtatgagc
    60181 tttgggtaac gaatattttg aattaaggaa aatagtgctg gaaaatattt cgttttttgt
    60241 acagagtagt ttatttaaga aggctgcgta gcgtatgtcc ggcacagctc ttttttcata
    60301 gtgaaagata aggtgataaa atgaataacc gaatccttga aacattggaa tttgaaaaag
    60361 tcaaacagat ggtcagacaa tttgtagtga ctgcacaagg aaaagaagaa ctggcagaat
    60421 tggtaccagt gagtgagaaa caaacgatca caaactggct tcaagaaact gaggatggat
    60481 tgaaagtgca acgtctgcga ggcgggatcc ctatacctaa acttgaaaat atccgtcccc
    60541 atatgaaacg gatcgagatc ggagcagact tgaatggagt ggagcttgca caagtttcca
    60601 gagtattgtc tacgacaagc gaattgaatc gtttcattga tgatctttct gacagtgaaa
    60661 tcgaatttgc acgtttgtat atgtgggcag atcagttagt cacgatccct gttttgagcc
    60721 gccgtttaaa ggaagcaatc gatgaagacg gacgcgtgac tgatgacgct tctcctgagt
    60781 taaagagcat aagacagaac attcggcgaa gtgaacaagc tgttcgtgaa cagttagatg
    60841 ggatcgtccg tgggaaaaat gcaaagtatt taagtgatgc gatcatcacc atgcgaaatg
    60901 accgctacgt tatcccagtc aaacaagaat accgcggtgt atttggcggt gtagtccacg
    60961 atcaaagtgc ttcaggacag actttattta ttgaaccaaa acaagtggtg gatttgaata
    61021 atcgtttgcg tcaataccaa atcgctgaac gaaatgagat tcaacgtatt ttaagtgaac
    61081 tttctgctga acttgttccc catcgtcaag aaatcatcca caatgcttat gtgattggta
    61141 aaatggatct gatgaatgca aaagcacgat ttggtaaaga agtaaaagcc atcgtgccgg
    61201 gaatcagtga agacaatcat gtcgtcttga aacaagcaag acatccactg atcgatcagg
    61261 aaaaagtagt ttctaatgac atcacaatcg gaaaagacta tcaagccatc gtcattacag
    61321 gacctaacac aggtgggaaa acgatcacgt tgaagacttt aggtctgtta caactgatgg
    61381 ggcaagcagg attaccgatt cctgcaggtg aagaaagtca aatcggtatt tttgaggaag
    61441 tatttgcgga tataggagac gaacagtcga ttgagcaaag tctatcgacc ttttcttctc
    61501 atatgacgaa cactgtagat attttatcaa aagtcaatga aaaaagtctg gtattatttg
    61561 acgagctcgg tgcaggaaca gatccgcaag aaggtgctgc tctagcaatc gcaatcttag
    61621 atgatcttgg taaaaagtct gcttatgtga tggcaacaac gcattatcct gaattgaaag
    61681 tttatggata caatcgggca aatacgatta atgccagcat ggagttcgat gtggatacac
    61741 taagtccaac gtatcgtttg ctgattggcg ttcctggacg aagcaatgcg tttgaaatct
    61801 ctagccgatt aggtcttgat acagaagtta ttgatgaagc gaagcagttg atgaatgatg
    61861 agagccaaga tttaaacgaa atgatcacag atttagagaa tcgccggaaa atggcagaga
    61921 ccgaatatct ggaaatgcgt cattttgttt ctgaggcaca agaacttcac gatgatttga
    61981 aagaagctta cagctatttc tttgaagaac gtgaaaaaga aatggaaaaa gcaaagaaaa
    62041 aagcaaacga agtcgtgtca gaggcggaag aaaaagcaga aaaaatcatt gctgatattc
    62101 gtaaaatgca acagcagatt gggcaaggaa atgtgaaaga gcatcagttg atcgatgcaa
    62161 agacccaatt agcaaatcta catcaagaag aaactttgaa gaaaaataaa gtattgaaga
    62221 aggcgaaaga acaaaaaacg ttgaaaccgg gagacgaagt gttggttacg acttacggcc
    62281 aaagagggac gcttttacgt aaaaacggga atcagtggca agtagaaatc ggtatattaa
    62341 aaatgaatgt gtccgaagac gagctgacgc ctgttgctcc tcaaaaagag ccgacacaac
    62401 gagttatcca tgctgtacga tctgaatcta gtagtcacgt gccgaatcaa ttggaccttc
    62461 gaggaaaacg atacgaagaa gcgctaagtg aggtagatca atatttggat tctgccattc
    62521 tagctggtta tcctcaagtg actattgtcc acggaaaagg aacaggcgca cttcgcaagg
    62581 gaattactga ttatcttaaa aaccatcgga gcgtcaaaag ctttgagttt gcaccggcaa
    62641 accaaggcgg aaatggtgcg acaattgtta aatttaagta aagcttacta aaggtaagca
    62701 gatggttcgc tatccaagta tagaaatgct atactaatca tagattttaa aaatggaggt
    62761 ctttgatatg tcacaagtaa ttacagataa gacatttaat gaagaaacag ataaaggact
    62821 tgtattgatt gatttttggg caacttggtg tggtccatgt cgtatgcaag caccgatttt
    62881 ggatcagttg gaacaagaat atgatgaaga agaattcaga attgctaaaa tggatgtgga
    62941 tgaaaatcca gaaactcctc aacaattcgg tatcatgagc attccaacat taatgttgaa
    63001 aaaagatggt caagtagtag aaaaagctgt tggtgttcat tcaaaagaac aactacgtca
    63061 aatgatcgat caatatttat aaaaacttac agcaaaaata agctgagggt gggactgaat
    63121 ccagttccgt cctcggtttt tttgcggttg agttaaggtt attcaaatta atattttttg
    63181 agtataatta cgttgtcagg ctggattgtt tttttgacag acatgctata ataactttaa
    63241 ttgaatatga aggggagtac cagatgaacg aacgaatcaa aaacaaatta gctttacttc
    63301 ctgatcagcc cggctgttac ttgatgaaag ataaaaatgg aacgatcatt tatgtcggca
    63361 aagccaaaat attaaaaaat cgtgtccgct catattttac tggcagccat aatacgaaaa
    63421 cggaacggct tgttagtgaa atcgaagact ttgaatacat cgttacagaa tcgaatatcg
    63481 aagcattgct cttagagatc aatctgataa agaaaaatga tcctaaatac aacattatgt
    63541 taaaggatga taaaacctat cctttcctta agataacgaa tgaaaaatat ccccgtttgg
    63601 tgattactcg taaagtacta aaagacaaag cactgtattt tggaccatat cccgatgtcg
    63661 gtgcggcgaa tgagacaaag aagatcctcg atcgattatt tcctctgaga aaatgcaaac
    63721 ctagtcagac gaaggagcct tgtctttact atcatttggg acaatgtctg tgtccttatt
    63781 atttcgacgt agatccgaaa gtctatacga aaatcgttga tgaagtgaaa aagtttttaa
    63841 acggaggaca cgaaaaaatc gagtcagaga tccatcagaa aatggaaaaa gctgctgaaa
    63901 acatggagtt tgaaaaagct gcagaatacc gagaccagat ccgtgccatt gagacaatca
    63961 tgactcgcca aaaaatgaca aatactgatt tactggatcg agatgtattt ggttatgcga
    64021 ttgacaaagg atggatgtgt gtccaagtgt ttttcgtaag acaaggaaag ctaattgaac
    64081 gagatgtttc aatgtttcct ttctataacg aagcagaaga agatttcttg acttacctcg
    64141 gtcagtttta tcaggaaaat gagcatttca ttcctaaaga agtcttgatt cctgatacga
    64201 tcgacaagcc cagtgtagaa gctttgttag ctacgaaagt gctgcaacca aaacgaggag
    64261 aaaagaaaaa attagttgaa ttggcgaata agaatgcctc agttgctttg aatgaacggt
    64321 ttgatctgat tgccagaaaa caggaacgga cgatcggagc agttgaacgt ttaggaaacg
    64381 cgatgaatat cccgacccca atacgtatcg agtcttttga taactctaat atcatgggga
    64441 cgaatcctgt ggctgcgatg gtcgtattca ttgatggaaa accggcaaga aaagaatatc
    64501 ggaaatataa aataaaaaca gtcaacggac cggatgatta tgcatcaatg agagaagtca
    64561 tctatcgcag atattcacga gtgattcgcg aagggttgcc tttacctgat ttgatcttga
    64621 tcgatggagg aaaaggacaa gtagatgtgg caaaagatgt cttagaaaat caattaggaa
    64681 tcgatattcc tattgctggc atggcaaaaa acgataaaca taaaacaaat gagttgctat
    64741 tcggtataga tttggctgta gtaccgcttg agcgaaattc accagagttt ttcttactcc
    64801 agcgaatcca agatgaagtc catcgattcg caatcacttt ccatcggcag ctacgcagta
    64861 aaaacagttt tgcttcccga ttagatgaaa ttgaagggtt aggaccaaaa cgaaaaaaaa
    64921 tgctgcttaa agagttcaaa tcgttgaaaa atatcacagc agccacgaca gaagaattac
    64981 aagaaatcgg actgccgaaa aatgtcgcac aaaacgtatt tgataaatta catcaggaat
    65041 gaggaaaggg cactttacaa agaaagtaaa gtgtcctatc attttatgta caacaaaaag
    65101 agcgtttacg ttttgttggt aaataataaa tcgcttacgt ctggtgtcta aggatatatg
    65161 tgatttcttg aagaaggagt gaagaaatgt tagaagtcaa ggatcttgtt aaaacttttg
    65221 ggaactacac agctgtcgat catgtctctt tccaaatccc cgatggaaaa atcatggggc
    65281 taattggcca aaacggggct gggaagacaa cgacttttcg tttgatcttg gattttttga
    65341 cacaagacca aggagaagtg ttatggaatg gccatcatct tggggagaaa gattatgatg
    65401 tcatcggtta tcttccggag gaacggggac tttatccgaa agtaacgatt caagaccaac
    65461 tgctttattt tgcagaactt agagggaaat caagaaaaga gattgaacca aaaatcgatt
    65521 tttggatgga aaaatttcag gtaaaaggga aaaagacgga taaagtaaaa tctttgtcta
    65581 aaggaaatca gcaaaaagtc cagctgatcg ccacgttaat ccatgaacct aaattgatca
    65641 ttttggatga gccattcagc gggttagatc cggtaaatgc tgaattgcta aaagatggaa
    65701 tattggaatt gaaaaaacat ggttcatgtg tcattttttc tagccacaat atggataatg
    65761 tagaaaaaat ctgcgatcat ttgatcatgt tgcgaaacgg aaaaatggtt ttgaatggaa
    65821 aagtacatga gattcgtgaa tcatttggcc gtacgaagtt attcttggaa tctggtttaa
    65881 gccaacagga agtagaagaa atcgaaggcg tgaaaaaagt gatccttcat gaagacaata
    65941 cgttagagat taccttagaa gatcctgaag ctgggaaaga aatctttact cgtgcgactc
    66001 agttcggcta cattcctatg tttaaccagc aaccgccaac tttggaagag attttcaaat
    66061 tgaaagcagg tgaaatcgat gcgtaagttt tggattatta ccaaagatgt ctatttaaaa
    66121 aatgttaagt cgatttcttt cttgatcatg atattagtcc cttttatcat gctgggtatc
    66181 atttatgtag caggaaactt tgctcaacaa aatagtgatg tcaataaaat cggcgtattg
    66241 gctgataatg agcaaatcag tcagcaaatg agccaagtca aaacagatga ttttgagttc
    66301 aaagcagttg attctgaaga aaaagcacaa aaagagcttt cggaagaaaa aatcgatgcg
    66361 tatttagtag tctcaactga gaatgataag ataaatggga tgctttatag cgaaaattca
    66421 ttaggacaaa gtacacaact actgatacaa caacaactga ctggcttgca atcgatgctt
    66481 cgagcaagtc aattaggcat ttcaccagaa gaagtagcta gcttgagcca acaagcaagt
    66541 ttgactcgac aaaaagtcaa ttttgattca aaaggaaaaa tgacagttgg agaagataac
    66601 tcgacagtcc aatatgtcgt aagttatgta gcaacgattg tcttgttcat tattattttg
    66661 acgtatgcgc agatcattgc acaagagatc gcttctgaaa aaggcacgcg gatcatggaa
    66721 gtgatcctgt ccagtacgac tgcacaaaag catttttacg gaaaactaac aggtgtttta
    66781 cttgttgcat taacgcaaat ggcattatac ggtattattt ttggtatagg atacagtcaa
    66841 ttcaaagata tggaaatggt caaaaatata ttagacggta tctcattgga taacttgatt
    66901 ggaccattct tgtggtattc tcttctattc atgatctttg gcattttgat tttttctgtt
    66961 ttagcagctt tatgtggctc tttggtcaac aaagcagaag atacagcaaa agcaattttg
    67021 ccagtgactt atctatctct aggcggatat atgcttggat tgatactagg agcttcagat
    67081 ccaaacaata tcgttattcg gatcacttcg tatattccat tcttatcttc atatattatg
    67141 ccggttcgct tagcaaatga gacagtcggt atgggtggag cattgatttc cttgttggta
    67201 cttgtagccg taacattctt attgatgatc ttgtctgcaa acatgtacaa atcgaatgta
    67261 ctcgtgtata gcgaaggcgg attatggagt tcattgaaac aatcgatttc aattatgaga
    67321 aatgaacgaa aaaaagcata aaatatagaa aaatatagaa ggaagctgga catttattgt
    67381 tcccagcttc ttttttgtat agacctattt ctattttttt attatattgg atatatattc
    67441 attgaaaata gagcataaca actttataat gttgagtata ccaatttttg gaggcgtttt
    67501 aatggaccgc tatttagatt tactttcaga gaagttccct acaacggaag atgtcatcac
    67561 ggaaatcatc aatctcgaag caattttgca gcttccaaaa ggaacagagt tatttttgag
    67621 cgatatacat ggcgaatttc ctgcttttga tcatattctg cgtatcggtt caggaaatct
    67681 taaagaaaag atcaaagacc ttttctctga acaaatgacg gaaacggaga tcagccaatt
    67741 cactattttt acggcttatc cagaatatgt gttgacgact gattggtaca aaaaacaaga
    67801 taaatcccag ctgatccatc gtttgatcga tcttttacgg tttacgacag tcaaatacac
    67861 tcgatcaaaa gttcgaaaag gattgccgaa agaatatagc tatatcattg aggaactctt
    67921 gtatatcgat gatcgtatca acgggaaaaa agactatgta aaaaaaatca ttgaacaact
    67981 tgtcttgatg aaggaagaag aaaaattttt aacaaaactt gcgcagacga tccaaaaatc
    68041 tgtcatcgat catttgcata tcgtgggtga tatttttgat cgaggaactc aagcagccaa
    68101 agtaatggat cgaatcatgg atttttcctc tgtagatatc cagtggggga atcatgatat
    68161 tttgtggatt ggtgcgtatt gcggctctga ggcatgttta ttgacgcttt tacggattgc
    68221 cgcacgctac aactatttat ttgaattaga gaaagaatat ggattaaatt tacgtccatt
    68281 attttctttt gcccatcaaa cctatcagaa gaatccagta tttaccccta aaaacaggaa
    68341 agatctatct gaaagagagc aagaagaatt agaaaagatc catcaagcac tttctatcct
    68401 ccaattcaaa tcagaacatc agttgttgaa tcgacgacct gaatttaaaa tggacgatcg
    68461 taaattgttg gaaaaaatca actatgagga atcaacgatc gttttagaag gtcagctcta
    68521 tgagttgaaa gggacttgtt ttcaaacgat ccagccagat gatcctaaaa aattcttgga
    68581 agaggaacaa aaagtgatcg atagtttgat gtattcattc cagcactcgt taagaatgca
    68641 aaaacacatg acgtttttga tcgaaaaagg gggaatgtat ctcacgaaca atcagcatgt
    68701 actgttccat ggctgtatac ctgtagatga aaaggggcag ctcttagcat ttgaattaga
    68761 ccaatcttat cgcggaaaag aactgctggg attttttgaa aaacagataa ctgaaagcgc
    68821 aaaagatttg actgcaaatg aagatttggc gaccgatttg atttggtatg cgtggagcgg
    68881 gccattttcg cctttattcg gcaagagtaa aatggcaact tttgagcgct attttctcac
    68941 agagcctcat acgcacgtcg aaaaaagcaa tccctattat cacttgcgag atgaagagtg
    69001 gttcagtgaa aaaattttgg cagaattcga tgcaaaagaa gaaggttcag caatcatcaa
    69061 tggacacacg ccagtaaaag taaaaaaagg agagtcaccg atcaaagcaa acggaaaagc
    69121 atttgttatt gacggaggtc tatccaaagc ttatcaaaaa acaaccggga ttgctggcta
    69181 ctcattacta tgcaattctt acggtttcca aatcgtgaca cattatccgt tcttgcctat
    69241 tgaacaacaa tttgcaaaaa aatctgatca aacgaatgta aaaaaagtga tcgagcagca
    69301 gctcccacgc aaacttaatc ggaatacgac aaaaggaatg gaattacagc aacagattac
    69361 tcaactccaa aggctgttgg attatcgaaa ggacgattga gaaaaatgct agccaacatt
    69421 gctcaataga ctaaaaagcg actgcaacaa aaggcgtgtc gcagtctcct tcggaattag
    69481 ctcaaaaaac ggtaaaatat tagaagctat ttttctgttt atttctctaa tactcaggtc
    69541 agggcgctga tttcacgacc tcttccttaa acggtgttct cctgccaact cctcggtcac
    69601 aagtcacaat atccaacaaa catgagaagc tgttttttga aattgctcct tgtgactcag
    69661 agttgaacgg caggctcacg acctaatcag aaaaacgatt aaaattcatt cacaaagaaa
    69721 tcgaataaac gctgttcaga tgaatctaca cgatgagaaa gttccggatg ccattggaca
    69781 ccaaggattt tgtgcatatt atctttactt tggactgctt caatgagtcc atcgttggaa
    69841 aaggcgatgg cttttaacaa aggagaaaga tctttgactg cctgatgatg ataggaattc
    69901 acaaagtatg aatcagggag aaggtcactt aataaactgt ccgaaacgat tttgacttcg
    69961 tgagttgcaa actgcggggc agtgggctgt tgttcgtgtt ttacggacca ttttggatat
    70021 aatgaaagat cttgataaag tgttccctcc aacacgacat tcaatagttg aagtcctcgg
    70081 cagactgcaa aaatcggttt tctttgtttc aatgcttcca agatcaatgc ctgttcgaat
    70141 tggtctcgtt gaatatttgt ttccgtcagt tttggatgag ggtcttccat gtaaagttgc
    70201 ggactaacat cctgaccgcc tgcaagaatg agtttgtcga ttttctcaat tagttgaggc
    70261 gctgaatctg gagacatgac tggcagaata agaggtaatc cttgagcatc taaaactgca
    70321 tccacaaatc cctgcggtgt atagcttact tgatttcctt ggaaagtatc tgtcgctcga
    70381 atcagttgat tcccggcaat gccgatgatt ggtttcattt ttattccccc taaagtagac
    70441 taattgtaac aaggatttaa aaaaatttaa actatgtaag acttgcccct atacttatct
    70501 gttcttgctg tgttactatc tgtaaagaga attttcgtgt gaaattcatg acgatagttg
    70561 aaaatattgc ttaatttgtt ataataaaaa gtaagcagaa ataaaaaggt tgggcgtaag
    70621 cttcaaggat ctagttcttc aaggggtgag aaggacattt tattgaaggg gcctgcctat
    70681 actaagttat ctttagaggt acatactttc aatgaaaaaa gaaagcatgt acctcttttt
    70741 taaatcgaaa ggaagtgaag caagtgttag aagctttgga acaaatccga aaagcagaag
    70801 aagaaaatga gaagcgtgct cgaaccctac ggcagcagtt gaagacctat gcagaagaaa
    70861 aagagcaaga attggagata atccaaacga acagtcggca acagctgaaa cagttggtag
    70921 aagaaaaaga acaattcgaa aagcaagaat tagaaaaaga aaaaatgaaa ttgaaagcag
    70981 aagcagacaa ggtgcaagca actttgaaag accaatatca aaagcatcag agtcaagcaa
    71041 tcggtgcaat cattgaaagg gtgaaagaaa cttatggccg tcactaagat ggaaaaagtg
    71101 accctcattt cagataaaag aaatcaggag aggattttac aagcagtaca aggaatccaa
    71161 aatgttgaaa tccgggatct gtatcaaaat agaacaaaca accagtgggt agaaaaatat
    71221 tttccagata ccacgattat tgataaagaa gcaaaattaa gcgctttagg caatcggctg
    71281 aaagacatcc aagaagctat ccaattcata caacaccacg gcgatagccg tcaaaagaaa
    71341 ctccatttga aacgtcaaga actttcctta caagacttgg aagcaaatta ttccgaagaa
    71401 aatttcatga ataaattaga agaggtcctt gatttaaaag aaaagtggga acagctaact
    71461 gaaaaacgtg atcgtttaga agaagaggaa gaatggcttc ttcattggca acagctggat
    71521 attgctccaa gtatgtatgc aagtaagacg accatttttg agatggggac tgtgagtgca
    71581 gcaaattttg aaagtttcaa ggaagaacta agtaagcttg atgacgttta tatggaagaa
    71641 atagattata cgccaaaaca agtttatctt tcgtatgttg ctttaaaaaa atcagttgct
    71701 gctatagaag aaattgctgg gaaatacggg ttcaataaag aaacgtatcc ttatgaacaa
    71761 aatcctaaag aaaaattgca agaaaccaaa cagcaattat ccattgttca cgagcagcaa
    71821 aaaaagataa cgacagcgtt aggtcagtgc agcggctata tccaagaatt tgaatgggta
    71881 gaagaagtca cacttgccgt tgcagaacgg gaaaaagtaa aagaacggtt tatccatgcc
    71941 acttatctga tcgttttgca aggttgggta gatgcagaag aaaaacagaa tttgatgcat
    72001 gtgttaaacg aaactgtatc agaagaagat atatacgtta gtttcgaaac accaaactca
    72061 gaagagattc agcaggaagt ccctactaaa ttgaaaaacc atccgcttat cgaacctttt
    72121 gaattgctga ctgaaatgta cagtctgcca aaatatgaag aagtagatcc aacgccttgg
    72181 atgacaccat tttatcttgt cttcttcggg atgatggtcg cagatgttgg ttacggattg
    72241 ctgatgctca ttgggacaat actagctcaa aaactatttg ttttaccccg cgggatgaaa
    72301 cgtttcgtaa aattctttga gattctctcg gtaccatcga tcatctgggg attgatctac
    72361 agttcatttt tcggacaggc attaccaaaa gaactatttg gtatccgctt gcctttccca
    72421 atcctatcta cgacggatga cgtcaatacg attttgattt tatccgtgat tttcggtctg
    72481 atacagatct tggttggatt attcgtggca gcaaaggaaa atatcaggag gaaagattac
    72541 ttgagtgctg tcagtgatgg ttttgcctgg caagggatcc tgattgggat cgttattgca
    72601 ttgattggtg tcatgttgat aaaaaataca gcatttgttt atcttggcgc ggggctatcg
    72661 atcattgctg ctttatgtat cttaatcgtg ccgattatcc aatcgccgtc taaagtcaag
    72721 ggtgctgcca aaggagcgta taatctttac ggattgactg gttatatcgg tgatttagtc
    72781 agttatacac gtttgatggc actaggtatt tcaggcggaa gtattggcgc ggcattcaat
    72841 atgctagttg ctttcatgcc gccagccgct cgattcagtg tagggatcct tttgatcatc
    72901 gctttacacg cactgaatat gtttttgaca ctgttaagtg cctatgtcca tggtgcacga
    72961 ttgcagtatg tcgaattttt tggaaaattt tatacaggag gcggacgtgc ctttgacccg
    73021 ctgaaaacgg cggaaaaata cgtcaacatc aatcataaga aaaaaaacaa taaataattg
    73081 gaggattttt atacaatgat ggattactta attagtcaaa atggtggaat ggtatttgca
    73141 gtattagcga tggcaacagc gacgattttt tcagggattg gttcagctaa aggtgttgga
    73201 atgacaggtg aggcagcagc agcgttaaca acaagtcaac ccgaaaaatt cggacaggct
    73261 ttgattctgc aattgcttcc aggtacgcaa gggttgtatg gattcgttat cgcctttttg
    73321 atttttatca acttaggaaa tgatatgtca gttgtacaag gattgaactt tctaggcgct
    73381 tctctgccga ttgcttttac aggtttgttt tcaggtatcg cccaagggaa agttgcagca
    73441 gcaggtatcc aaattttagc gaaaaaacct gaacatgcta caaaaggaat catttttgct
    73501 gcgatggttg aaacatatgc gattttaggt ttcgttattt ccttcctatt agtattgaat
    73561 gcctaagcat aaaggaggaa aagcagatga acgccattga aaaaatcatc tctcagatga
    73621 atgaagcagc agagcaagaa agagcggcgt tagagcaaga agagcgaatg aagatcgatc
    73681 aaaactttga acaaaaacgt acgcaaatcg aaacagaaca tcaaaaacaa aaagaaaaac
    73741 aaatcgaatt acttgaaaaa aaataccgtc agcttaggaa tcgccaacaa gtagaagtac
    73801 gacaagaaaa tttgaatgcg aagcaggaat ttttacgacg attgtttgca gatgcaatag
    73861 ctgaaatgga gaattgggat gaatctgaac aaatccagtt tatcaaaaat tcattgtatt
    73921 cattaccttt gacaggcaaa gtaacattca ttgctggaga aaaatcagca gcttatcttt
    73981 ctcagacatt gctggatgaa tggaacaatg aacttccctt tatgatggtt ttaagtgatg
    74041 aaactgttgc tgatcaagcg ggttttctga taaacgatca aggagttcag tataattttc
    74101 ttttcagcag ccttgtacaa gatatccaag gaacgatgag ttttgagatt gccaatcaat
    74161 tattcgaata aggagggatc agtgtatgga ataccacgaa ctaaatccct tgattcgcgg
    74221 aagagagctt gaacttttgt ccaatgagac atttgaacgg atgattcaaa caaattctgt
    74281 cgaagcactt ggtgaaatat tgaaatccac gatttacagt ccatatattt atgacggata
    74341 tgaatatgac ttcgaacaga atcttttaaa ggagcagagc cgtctatttc gctggttaaa
    74401 ggaatcagca ccggagcctg aaatcgtttg gatctatacg atgcgctata ctttccataa
    74461 tctgaaggtt ttgacaaaag ccgagatgac aaatcaaaat ctggaccatt tgtatatcga
    74521 cgatggattt tattcattag aaaccttgaa ggatgccatt catacgcaag tttcaaatga
    74581 actccctgaa agcattatgg acagtatacg agaagtacgt gattattttg aagagtctac
    74641 cattcttcag ggaattgacg tgatttatga tcgacagttt ttgacagagc agcgacggct
    74701 tgccgataag ctaggatatc aagaattgct gacagaagtc attgctttta ttgacttgac
    74761 caatatcaca acgatggctc gaggaatatt gcagaaaaga acatatgggt tcatgacgac
    74821 ggtactttcc agctcgggaa gtatcgaaaa agaagtattt ttgaactttg tagataaaga
    74881 tatggaagat tacacgaatt ttctattaga gacagattat gctgattttc tgcgccctgt
    74941 catccgtgag ggaaatcttg atctcgtaaa gcttgaacag ttgaaagatg attatctaag
    75001 ttcattgtat caagaagcac aaacccaggc tttcggacca ctgccactac tagccttttt
    75061 gaacgcaaaa gaggtagaaa gcaaaaacct tcgtttactg gttatcggca aaagaagcca
    75121 tttcgaacca gaaacaatca gaaagcgggt gagacaagtc tatgacgcat aagatcggtg
    75181 tagttggcga caaagattct gttttgccat tcaaattgtt tggctttgat gttcgttatg
    75241 gtacaaccaa gcaaaccgtt cgtcaggcaa ttgaagaaat ggcaaagaat gagtatggcg
    75301 tgatttatgt cacagagcaa tgtgcagcat tgagcccaga aacgatcgaa cgttacaagg
    75361 aacaaatgat acctgctatc gtattgattc ccaatcatca aggatcatta gggatagggc
    75421 tggaagaaat tcaaaaaaac gtagaaaaag cagtaggtca aaatatctta tagtatgaaa
    75481 aggagataga aattttgcaa attggaaaaa tcataaaagt ctccggacct cttgtaatgg
    75541 ctgagaacat gtctgatgcc agtatccaag acatgtgtct agtgggagat ctaggagtta
    75601 tcggagaaat tatcgagatg cgtggcgatg tggcgtctat tcaagtatat gaagagactt
    75661 ctggaattgg tccaggcgaa ccggttcgct ctactggtga agctttatct gttgaattag
    75721 gaccagggat catttcacaa atgtttgacg gaatccaacg gccattagat acctttatgg
    75781 aaatcacaca aagtaatttc ttagggcgcg gagttcaatt gcccgcattg gaccatgaga
    75841 aaaaatggtg gttcgaacca acagtagaag ccggagaaac ggtgagtgct ggagatgtta
    75901 tcgggatcgt agaagaaaca aaagttataa aacataaaat catggtgcca aatgggataa
    75961 aaggtacgat caaaacaatc gaaaaaggtt cattcactat tgatgaaaca gtatgtgtca
    76021 ttgaaaccga aaatggtgac aaaaatttga cgatgcttca aaaatggcca gtaagacgta
    76081 gtcggccaat caaagaaaaa ttaaacccgg atgcacccat gatcactgga cagcgagtga
    76141 ttgatacatt cttcccagtg acaaaaggag gagcagcagc tgtacctggt ccttttggtg
    76201 cagggaaaac agtcgttcag catcaaattg caaaatgggc cgatgtggac atggttgtct
    76261 atgtgggatg tggcgagcgt ggaaatgaga tgacggatgt tttaaatgaa ttccctgaat
    76321 tgattgaccc taatacagga gaatcgttga tggaacgtac ggtattgatt gctaatacat
    76381 caaacatgcc agtagcagct cgagaagctt ctatctatac gggaatcaca attgcggaat
    76441 atttccgtga catgggttat gacgttgcta tcatggcaga ctccacttca cgatgggcag
    76501 aagcacttcg tgagatgagc ggacgtttgg aagaaatgcc tggtgatgaa ggttatccag
    76561 cttatcttgg ttcacggctt gcggaatact atgaacgatc tggaagagtc attgcattag
    76621 gatcagaagg tcgcgaagga agtataaccg caatcagtgc tgtatcgccg tctggagggg
    76681 atatttcgga accagtcaca caaaatacat tgcgggtcgt aaaagtattc tggggtcttg
    76741 attccagttt agcccaaaaa agacattttc cttcgatcga ttggatacaa agctattctc
    76801 tttattcaac agaagtaggg aagtatatgg atcatatcct tcaagctgac tgggcatcca
    76861 tggtcaccga gggcatgcgt attttgcagg aagaacagca gctgaatgaa atcgtgcgtt
    76921 tggtagggat tgattccctt tcagataatg accgtctgac attagaagtg gcaaaatcca
    76981 ttcgtgaaga ttatttgcag caaaatgctt ttgatgatgt cgatacattc acttcaagag
    77041 agaaacaatt caaaatgttg aagatgatct tgacctttgg tgaagaagga cgccgtgcgt
    77101 tgtcgttagg tgcttattta agtgagatca tggacggtac cgtatcgatt cgtgaaagga
    77161 tcggacgaag caaatatatc ccggaaacag aattagaaaa actagatcaa attattggtg
    77221 aaatcaagca aacgatgcaa acgatcgttt cagaaggagg catgagcaat gattaaagaa
    77281 tatcgtacga tcggtgaagt cgtcggtcca ttgatggcgg ttgaaaaagt tgctggtgtc
    77341 aaatatgaag aattaatcga agtccgtatg caaaatggcg agattcgtcg tggacaagta
    77401 ttggaagtcc aagaagataa agcaatggtc caaatattcg aaggaacaag tggtatcaat
    77461 ttacgtgact cttctgtacg atttttaggc catcctttag aactaggtgt atcggaagac
    77521 atgatcggtc gagtattcga tggtttggga cgaccgaaag ataacggacc agagatcctg
    77581 cctgaaaagc atttggatat taacggagaa gtaatcaatc cagtagctcg ggattatcca
    77641 gatgagttta tccaaacagg tatctctgca atcgatcatt tgaatacatt agttcgtggg
    77701 caaaaattac cagtattttc tggctctggt cttcctcata aagaattagc tgctcagatc
    77761 gcgcgacaag caacggtact cgattcatca gatgatttcg ccgtagtctt tgctgctatt
    77821 ggaatcactt ttgaagaagc agaatttttc atggaagatt ttcgtcaaac gggcgcaatc
    77881 gaccgttctg tcatgtttat gaatttagca aacgaccctg caatcgagcg tatcgctact
    77941 cctcgtatgg ctttgactgc tgcagaatat cttgcttatg aaaagggaat gcatgttttg
    78001 gttatcatga cagacatgac caactatgca gaggcattgc gagagatttc tgcagcacgg
    78061 cgagaagttc caggaagaag aggatatcct gggtatcttt acacgaactt agctacttta
    78121 ttcgaacgag caggaagaat ccgcggacta aaaggatcgg ttactcaaat tccgattcta
    78181 acaatgccag aagacgataa aactcatcca atccctgact tgactggtta tattacagaa
    78241 ggacagatca tcttgactag agagctttac aagagtggga ttcagccacc aattgatgta
    78301 ctcccgtctc tttcgcggtt aaaagataag ggaactggac ccggaaagac aagagaagac
    78361 catgcagcta cgatgaatca gctttttgca gcctatgcac aaggaaaaca ggcaaaagaa
    78421 ttggccgtag ttttaggtga atctgcttta tctgatgtag acaagatcta tgcgaagttt
    78481 gctgagcggt ttgaaaaaga atatgtcaat caaggattct acacgaaccg ttcgattact
    78541 gaaacacttg atctagggtg ggaactgcta tcgatgttgc caagaaccga attaaaacga
    78601 atcaaagacg acatgctgga caaatatctg ccagaaggga agtgagttct gatggcacga
    78661 ttgaatgtga atccgacccg catggaattg actcgattga aaaaacagtt gacaactgcc
    78721 acaagagggc ataaattatt aaaagataag caagatgaac tgatgcgtca attcatcctg
    78781 ttgattcgaa agaacaacca gctgcgtcaa gaaatggaag agtctatgac agaagcaatg
    78841 tctgattttg tattggcaaa tgcttcgatc acggagcctt tcatcgaaga attatttgtt
    78901 ttgccggcgg aaaacgttga tttgtctatc gtagacaaaa atatcatgag tgtaaaagta
    78961 cctgtgatga attttgaata tgatgaacag ctgacagaca cacctttgga atacgggtat
    79021 ttgaattcca gtgccgaact ggatcggtca atcgatcggt ttactaccct gcttccaaaa
    79081 cttttggaac tgacagaaat cgaaaaaact tgtcaactga tggcgagtga aatcgaaaag
    79141 acacgtcggc gagtcaatgc attagaatat atgacgatcc ctcaattaga agaaacgatc
    79201 tattatattc gtatgaagct ggaagaaaac gagcgcgcag aagtaacaag gttgatcaaa
    79261 gtaaaaaata tgggtaccac tgactaagtg gtatcctttt ttaaaagagg aaaacgatga
    79321 ttaaacaaag caaacaaata aagaaacgct tgccggctgt tcagcttctc gcattaggat
    79381 tttttctcct gattttagtt ggcggcggcc tacttaccct accatttttt agtaatagtg
    79441 ggcatgggac aaattttatc gatgcgcttt tcactgcaac ttctgctgtc tgtgtgacgg
    79501 gattgacaac attgaataca gcagagcatt ggaacagtgc tggtcaattt ttgatcatgc
    79561 ttttgattga gatcggcggt cttggtttta tgatggttcc gattctatgc tttgcattga
    79621 taaagaagaa agtcagtctc agcacacgta ttatattaaa agaagcgctg aatctagaag
    79681 aagtatcagg tgtgatgaag ctcatgcttt acatcctgaa atttgccttt gtgatccaac
    79741 tgattggtac ggttgcttta tcttttgtat tcgtgcctga atttggctgg ttgaaaggta
    79801 tctggtacag tttgttccat gcaatctcta gtttttgtaa tgcagggttt gatttgttag
    79861 gagacagttt agccaatcac cagcaaaatg tttatttgat catggtggta tctgctttga
    79921 tcatttctgg tgggttaggc ttcatcgtat ggcgtgattt actggaatat catcagaaaa
    79981 agaagataac gattcattca aaaatcgcat taaccgttac aggtaccctt ttattaggcg
    80041 gattcgttgt gttctttttc acagagcgca atggggaaac gctagtggaa gggaatatgt
    80101 ttcaacgatt ggcaaacacc ttttttatga gtgtgacacc tagaacggct ggatattatt
    80161 cagttgatta cctccatatg agccatgcag gtctgatttt aacgatgttt ttgatgtaca
    80221 tcggtggaac atctgggtcg acggccggcg gattgaaaac aactacgtta ggtgtgttgc
    80281 tgatccagat gcgttcgatg cttaaaggac gtacgagagc ggaagcattt ggccgtacca
    80341 tccgacaagg cgcagtgttg cgggcactta ctttattttt tgttacgttg acgttgtgtg
    80401 tagtcgccat catgatttta tcggtgactg aaacgatacc taaaacttct ggcatcgaat
    80461 atattgcttt tgaggtcttc tctgcgtttg gtacagtagg tcttacgatg ggattgacgc
    80521 cagacttgac tgcaataggg aaattgatca ttatagcgct tatgtacatt ggacgagttg
    80581 gtgtattgac tgtggtcttc tctctgatga caaaagcaca aagaacacaa tcaaaataca
    80641 aatatccaga agaaagtgtc atgattggat aatttcatct tctgacagaa acctagtgat
    80701 ttagtaaaat aagaaaataa aataattttt cttgcttctt ggatacttta agtgcaaaat
    80761 gttcgtttat tttttgaggc actatccgtt gttgaacctc gggtagtgcc tctttcttat
    80821 tgaaaggaat caataagatt tgattccttt atttatcaat aggttataat tcatattttt
    80881 ttattttttc ttttacgata cttagtccag aagctaaaat ttcaaggtta ttagaggata
    80941 gggaaattcg aacgaatgca tctggttgcg cacgtgtagt aaagcgtctg gaatgataaa
    81001 gtcggatacc gttagcaaga aagtcattct caattatctt aggatcaatc tcaggatcaa
    81061 ctggaagaat tcgatagtaa gggacacgat tcgttggttt ttctactttg aaaagagaat
    81121 caaaaagctg attggctctt ttcgtaagac ttaatttagt ttctaagatc ctatttgctt
    81181 catttgaatg gaggatttga gtgatgactt ccacatctaa tccagaagtt ttcacattta
    81241 tattaaaaat tgcttgttct atcttgtttt ggacatgtac tggaactaca agataagcaa
    81301 ctcgcaatcc agaacaaata aattttgtca ttccagctaa gtagattgtt tggttaggta
    81361 ataatttttg gaaaggagga atgatcgtat gttgatagta agttgttaaa aatgaatgga
    81421 tatcatcttc aataacccat agaccttctt tttcaatcac ttcggctaat tgctctcgtc
    81481 ttttgtgaga gatttgaaac cctataggat tattacaaga aggcataaga aagacaccat
    81541 gaatcttctt ttttctacat tcctgaatca atatatcagg tcgcattcct tgctcgtcaa
    81601 aatcaattgg aacgatctct aaatgatata actgagccaa ttcaatgaaa ttagcgtatg
    81661 tatatcggtc tgttgctatt ctatcacctg gagagaaaag tgcagaaagt gtgatagcca
    81721 atccattttg aacaccggaa acaatagata gagattctaa ggacggaatg actccttgag
    81781 tttttaacca atttgctgca gtagtcaatt gaaaatttgt gcctttggga tcttggtaat
    81841 taagcaaacc aacaagattt gggttattac tagttgattg aataaacggg acaacgaatt
    81901 tattacattc ttcaaaagaa ctaaccagac caaaatcaat gatatgttcg gttacttcat
    81961 tggtagagat ggtgatggac tcaaagacat tgggagaaat aaatgtgcca cttccaatat
    82021 tcgtatacag caaacctttc tcaattccat atttataagc cttgccaacg gtagtaaaat
    82081 ttaaatctaa ataatcagct agctctcttt gggagggtaa ctgagtgttt ttctgtaatt
    82141 tattctttaa aatatcttgt tctaattgtt gaatcaacga tcgataataa ggacgcttca
    82201 atttttgttt gtctggtcgc caagttaacg ggtaattgtc ataagaatta ataggcattt
    82261 tctacactcc ttaaaattgt ataccataca attttaccat tgattgtatt gattttagaa
    82321 gttaatcttt tgtgaggagg gaattgtcta tgaaaattat taattttgag gaagtagtag
    82381 cttcttttag ttttgaagaa gcgattcaag taatgaaaaa atgttttttt gattatgaaa
    82441 gtggtaaaat cagccaaaat cctcgattgg tggaaatttt acctgacgga aaagacaaaa
    82501 atatgtttgc gatgatgcct gcttatttgg gggagaacag atattttgga acaaaagtca
    82561 ttaccgcttt tccggataat catcagtatc atttaccttc tcatttagga gagattttct
    82621 tgtttgatgc tcaaaacgga ctacccaaag cattgataaa cgcaaatgca gtcacctgga
    82681 ttcgaacagc tgctgtatct gcgctggcaa cagattactt agcaaatccg catgcagaaa
    82741 cacttgcttt aattggagct ggtcaacaag cattgtcgca tttgactgcg atttctacca
    82801 ttcgtcccat cactacagtg tttgtttacg atattttaga agaaagacga aatactttta
    82861 tcgctaaagc taaaaaacag tatcctaaaa taacgtttat aaatgcaata tcagtagaag
    82921 atgcagtacg tccagcggaa atcatttgta cgttgacctc tagtaaagag gcatttcttc
    82981 aaaaagagtg ggtaagggaa gacgcacata tcaatgctgt gggcacattt actcctgata
    83041 caagagagat aagtacatcg ttgatggaaa cttctcaaat ctatgtagat gattactcag
    83101 ctaccttaac agaaagcggg gacctgctta tagccatggc agaaggagat ttagaggaat
    83161 cttgtattgt tggtacatta ggcgaattag tttctgagaa aaaaacattt tataaaggag
    83221 aatcgaggcc gacgattttc gacgcagttg gtctagctat tgaagatctt tgttgtgcag
    83281 aatatattta taacaaatta gagaaagggg ctttaaaatg aacttagatt attacgtagt
    83341 tgatgcattt gcagatgagg tgttcaaagg aaatccagca gcggtttatg tgctagaaga
    83401 atggctgcca gaaggtacga tgcaaaaaat tgccattgaa aacaatttat ctgaaacagc
    83461 atttacagtg aagaaaaacc aagaatttga gcttagatgg tttacgccag atcgagaaat
    83521 cgatctttgt ggtcacgcga cattagcaac agcatttgtt ttatttaact attacaaaat
    83581 acctgatgaa acgattaaat tttctactca aagcggtaat ctatttgtga caagaattaa
    83641 agattattat tacatggatt ttcctagtat tatgccgaaa aaagtgccga tattgactga
    83701 atatgaagaa gcaattgggg ctaagattaa agaagcctac ttagcacgtg atttattttt
    83761 cgtattagaa gatgaaaaaa cggtggctaa attgcagcca gattttacag ctatcaaaaa
    83821 ttttgaatta ggaatagagt catcgtgaca gcagaaagtg tgcaaaaaga ctttgtttct
    83881 agaaccttct ttccaaaatt aacaatcaat gaagatccag tatgtggatc agcacattct
    83941 aatcttattc cttattgggc agaaagaatg aataaaacaa aattgtcagc ttatcaaatg
    84001 tcatcaaggg gcggggatct agaatgtgaa ttaaaagaag atcgtgtgat aataggagga
    84061 aaagcagttt tgttttctaa aggtacctcg tttatttgat ttctttcaaa tgaattaaaa
    84121 ataaattggt ggagagtggc agccttatag ctacaatggt tgttaaaaaa agacgcaaac
    84181 tttttcaatt taatgaaaag tttgcgtctt tttttaatta ttggtgtttg ttttttattc
    84241 aatcaagagt aaaatgcccc atactaacta tcctcggatg acttcgattt tataaccatc
    84301 agggtcaatg acaaagtagt aagaaggcgt agtgccaggt aatcctttta agtcagtaat
    84361 ctcaagacct gcagctttat gttgctcgtg taatttttct aaatcatcag ctgcaatagc
    84421 gatatgacca tagccgtctc ctagatcata cgcaccatga tcatagttgt aagtcaactc
    84481 taattcatag tcatctccag gaagtgtcaa ataaacaagt gtaaatttgt tttctggaaa
    84541 atcacggcgg cggctttctt caaaaccaaa tgccttttga taaaattcga ttgatgcttc
    84601 aagatctttc acccgaacac atgtgtgagc cattttcata aattcatctc tccttttcct
    84661 tttactcaat cataacaaaa agaagtaaga aaatagttga tttgtgcttg ttcatgagaa
    84721 atttctcatg taaaatggat agaaaataat actgttaagg tggaaacaat tcatggataa
    84781 accaattttt ggtgaaaaaa agcaatctgc taattatcaa acccgttatg cagcatatat
    84841 tgtcatagaa agagacaagc ggattgcggt gatcgaggct ccaaatggtg cttttttcct
    84901 tcctggtggg gaaatcgaag gagaagagac gaaagaagaa gcgattgtcc gtgagctgat
    84961 agaagaaatg ggaattgtgg cagaaatttc ttcttatctg ggagaagctg atgagtattt
    85021 ttactcgaat tatcgtgcaa cttattatta taatccagga tatttctttg ttgctgattc
    85081 ttggaagcgt ataggagaac caactgaaaa gaccaataaa atttggtggg tgagccctca
    85141 agaagcgctt gtgaaattga aacgtggtag ccaccgatgg gcagtcgaga gatggatcga
    85201 aaaaaataaa aactgaaaga aagcgagtag atcagctttc tctcagtttt tttatttatt
    85261 acagtacata ttttttgatt gcttcagcta caccgtgctc gtcgtttgat gaagtgatga
    85321 catttgctgc ttctttgaca agagaaacgg catttcccat tgctactcct agaccagcat
    85381 attcaatcat ggataagtcg ttctcgttat ctccgatagc catgatttca tcttgatcaa
    85441 taccaaggtg ctgtgcgaga ttcgcaactg ccgcaccttt acttgcttct ttatttagta
    85501 cttcgaagta atagggcgca cttttgaccg ttgtgtattt atcacggaaa gtttgcggta
    85561 aacgcgcaat tgctgcatct aaaatttctg gttcgtcgat catcatcatt ttgacgatgt
    85621 tcatgtctgg tgtcatttct tcaggtgttc gatattttag cggcatcttg actaaacttg
    85681 cttcgtggat cgtataagcg ctgatatctc gattaggcgt gtagatcgct ttgtcatcga
    85741 tcgaatggag atgactgccg acacggcgtg ccatcacttc gatctctagg aaatcttcat
    85801 gagtcagtcc gtgacgggcg atgattttac ctgatttcgt ttgttgtacg agtgccccgt
    85861 tataagtaat aacgtaatca ttatcttgaa aaaggttcaa ctcgtttaac tgttcctgga
    85921 cacctggtaa gggacggcca gtgcataaaa cgatcgaaac accttttgca acagcagcgg
    85981 caatcgcttc ttttacttct tttgttactt ctcttttctc atttaataaa gtaccatcga
    86041 tgtcgatagc gactagtttg atagacataa tttcctccaa tatattttaa tttatttcaa
    86101 tcaatgcgcc attacggata tggctggcaa attcttgata agtttcgtca aataaatcat
    86161 aatgatcacg caaggaggga tcaaccattt cttttggaaa gaaaaatcgc tcatctcctt
    86221 gttcttgtcc cgctaatgca gcaacaagct gactaacctg tgataattct atcaaagttc
    86281 cgtcatttcg caaaatctcg atttgtgtgc gatgtctgcc ttgttctggg cgataaaaat
    86341 cataaggcag atcgtagcta gaattcacag cagtgtaata aacagggtta tagccaacct
    86401 tttctactaa caaagtgagt tcttggacta attttgaatc ccggttgcca gaaaaagtag
    86461 cagatttcag tggtttacga ttcaaaaaac gtttagctaa atcatttaaa ataggatcag
    86521 cagattcaga ccattgagta aagtaagtgc ccaagacccc atcatcaagt ttgaggtatt
    86581 cttctaaagt aaagcttccg tcaagaaatg gcagaagtaa ttgagaatgg agttcaaaac
    86641 tgctggcatc ttcttgatac aactcgtgtg cgcgatgaag cagatgctcc aaaatcactt
    86701 ccataccacg ggaaacagga tggaagtaca cttgcacata catttgatat cggctaacga
    86761 tataatcttc cactgcatgc atgccactca tggaaaaagc gatcccgcct tcataaggac
    86821 gaatcacacg taatattcgg gtaagatcaa atgttccata ttctgttcca gtgaaataag
    86881 catcccgaag caaatagtcc attcgatctg catcgatctg actagaaatc atttggacaa
    86941 cttgtgggtt ggggtaagtt ttttggatca cactagctac cttttcagga aaaccttctt
    87001 ctactcggtt aagaatctga tacacttctg tttctggaga agtgatgatc tctacagtga
    87061 tggcttcatg attcgtatgg aagatatgtt caaatgtatg agagtaagga ccatgaccga
    87121 catcatgcaa cagtgccgca cataaagtca ccagccgttc ctgatcatcc cagcctccgt
    87181 tgcctatttt ttcttttgaa aaatttcgag aaaagatatc gcagattcgt cttgaaatct
    87241 cataaacgcc taatgaatgg gtaaaacggc tatgttctgc tccgtgaaaa gtgaaagaag
    87301 aagtgcctaa ttgtttaatg cgtcgtaaac gttggacttc tttcgaattg atcaaatcta
    87361 agattacttt atgctggaca tggatatagt tatggactgg atcacgaaaa actttttcca
    87421 taggcagcat ttgatattta taaggggttg tcataatgta gctcctttat gttattacgt
    87481 tgttccattc tctggatttg gttgttccat tgctccagct ggatttcttt ttttagccag
    87541 tcggtagaat cctgtaaatc acttgcagaa tacagctttt caaaagcttt tgcaaatgct
    87601 tctttgactt cttttacaaa aaggggttgg tcaagcagtt cttcaagtgt tgccattgta
    87661 gcaggatcca ctgcaggata gccatttgta ccaaagtctt cttttaaagc agattgataa
    87721 aatcgcttca tgacttgccc gcgtttttcc tgattaccgt tgacacttaa gtacatcata
    87781 acagaaatcc catttttgat ccgacgctga gcgataccgg caaatttttt gccatggatg
    87841 cttaaatcat aagttccagg acaataagaa tgggtgattt cgaatgcttg tatcggtgcc
    87901 tttggaaaag cgtatttagt caataggagc atttgctcgt aagcgtcatc tatggttatt
    87961 ttttttgtgt cactttgagg gaaaatcaaa gaaatattta aaattccttc atctgatacg
    88021 atccctaatc cacctgaatt tctgatcact ggagcgtaac ctgcatcttt cagtgtttgg
    88081 atcccgtcac ttagaaaagg agttcgaaca tccttcatac ctaagatgac tgtgcagtca
    88141 tattgccaga aatgtaaaaa gatttgctgg tgttctttag aatattccgt taatatatct
    88201 gttaatgcaa aaggggaaaa gtcgtttttt tgataaatgt gctgatctag tcgaatcgca
    88261 gggttcattc aaccggctcc tttgtataaa ttcatatttt ctacaatatt atactctaaa
    88321 atcaaagagt tgttttggaa aaaaggtttt ctgtaaaaat ggacaagttg gttgacaaaa
    88381 caaaagaaac taggaacaat gtagctatga gaagtaaagg agaatgaata atggaattat
    88441 cacaaggaac accgatttca atcaaattgc gtacaaaagt aaaacagcaa ggggaagtgc
    88501 aagattttta ttttgatttg aaagggcaaa tggtgacaat tggcgatacg ctgtacatac
    88561 gttataaaga gattcaggag gagacgggcg atgagattcc tgtaacgatc aaattagttc
    88621 cagatggtca tgtacagctg atccgtgcag gagaaatgcg gatgcgtttg aaatttggct
    88681 ataaagaacg gttagaaaca tcctatcgaa caccatacgg tatgatccag attgctactt
    88741 ttacgaaaga actgcatgtt agtttgaaag accgtcccac agcagggaag gttcgaatcg
    88801 attatgatct gttcatggga ccggaaaaaa tcggcgaata ttatttgacc ttggatttta
    88861 cagcgtaaat ataaaagaaa agtttgattt tttgtgtctg attttgtatg ataaggagta
    88921 gactgtgaaa ggacgtgtcc tgattggaaa ttagtgtatt tgaaggtgca aacaaaagcg
    88981 aattatcaat gatcgaagta gcacacgcga tcttagaaca acgtggcgat gtcatggatt
    89041 tttctgattt agctaaccag atccaaaact atcttgagaa atcagacagt gaaattcgtg
    89101 attcactcgc acaattttat actgacttga atattgacgg cagctttatc tcattagggg
    89161 ataatcgttg gggcttgcgt tcatggtatg ctatcgattc gatcgatgaa gaagtaaacc
    89221 atggaatgga cgaagaggat gaagatactc cacgtcgccg taaacgcaag aaagtcaacg
    89281 cctttatcaa tgatgatgaa gacgcgatcg attacaatga cgatgaccca gaagatacag
    89341 atctgacaga agaagatgac gatgatctgt ttgatgacga tgatgatgaa gatgaagaaa
    89401 tcgctgctta taattctgac ttgcaagaaa tcggagcaga tgacccgaca gatgatgaag
    89461 aagacttgcc aggaaatatc gaagaagatt taagtatcat agacgaagac gatgatgatg
    89521 aagattatga agaggaagaa ttttctgact ctgaaaaaga ataaacatta ttttcttacg
    89581 agaggttgtg acagagacga tcagcctatc agaataagga ggtgtgacac gatttttgtc
    89641 acaccttctt ttttgtatat aaaaatccca agtaaataca taaaaaataa aaaaattgaa
    89701 acttttagcg caccttgtac gtcatattaa gtgaggcaga aaggagtgga gaatgatttt
    89761 tactggatat aagaaaaaac ggcagatcga aaaataccgt cacctgctga atggactcat
    89821 cgaaactgat tatcaaaaaa tgttccgtat cacgatgaat tacgtacatg ataaagaaga
    89881 ggccttagat gtgatgcaag atagttttca taaagccttg aactattttg aaaaagaaaa
    89941 agagatcgag cattttagtg catggtttta tcggatattg atccgcacgg cattagatag
    90001 ttggcgcaga caaaaaagga cgcctgtgga cttatttgaa attcaagata tcccccaaca
    90061 gttaccttta gaaacttccg ttgcagagct ccatatgatt ttagataaaa tagacagtcc
    90121 ggaaaaagag attctgatcc tctacttttt tgaaggattt cgtttgaaag aaattgcaac
    90181 tatcttggat atgaatgaaa acacagttaa aacgaaaatg taccgctcat tgaatgcttt
    90241 acgtcaaatc ctagaatgaa ggagagaaga gtgccatgta ttcccaaaaa gaaaatttaa
    90301 aaaaactaaa gaaaacttat aaagaacaag caattcccaa agggcttaaa gaggagatcc
    90361 gccagcgttt tattatcgaa gagcaatcat ttataaaagc aaggcggaga aagagacgtc
    90421 tccaagggtt cggagtatct ttggctatcg taatgattac aacaagtagc cttcttttta
    90481 atagtcaagt tcgaagcttt gcagaagatt tacccatctt aggatcagtc attgaattga
    90541 tcttaggcga acgctttact gatcgatctg aaaaaatcga tattcaggta ccgaagatca
    90601 atacacaaaa tgagaaagaa aataaaacaa ttcatggatt aaatcaaaaa tactttcgcg
    90661 aaggacaagc agattttgaa aaagctgaaa aagaatatgg aaattttgaa acggatcatt
    90721 accaagtttt gggagattat cagaaaatcg tagacgataa ccggtttctc gtgattgaaa
    90781 ggcagatcac ccaaacagca gcagatagcc atgttgaaaa aagatacgac acaatcgaca
    90841 agaaaaacag tgtccagctc tcacttccac ttttattcaa agatgacact tatctatctg
    90901 ttttgacaaa agaagtcaaa cggcagatgg ccgaacaagt caaggaagat ccatctaagt
    90961 actattggac tgagcaagat attcaagaag ggacgataga aaaaccaaca cttgttacgc
    91021 ctacacgaag tttttatttg aacaaagagc atcaattagt tttgactttt tctcaatacg
    91081 aaattgctcc tggttatatg ggtacaccag aatttgtcat tcctaagtcc gtgacaaaaa
    91141 cgattttggc atcggaagat tatttggatc attagacgag aagtagttgc gactagcagt
    91201 ttcaattttc aagtaagtac aagtaaataa taagaagaga aaaagagaaa gaagagatat
    91261 agtgaaaaga aattatttag tcatcagtat tattgcttta tccgtgcttt tgtttttcga
    91321 aattacttcg gtggcctcct tgatcaccga agtaaaagga caaacacact cttcggagca
    91381 ttcgtcacaa tctttcaaac aatcagaaca atcaaccatt aaaagccaat caactgaaac
    91441 agctaacgtc aaagaagcca ttcaagaatc agcggaaaag gtacaaagtc aatcatcaca
    91501 atcaacacaa gacagtacag aagcaatcca agacccgact gtcaaaagcg tcgcaatcag
    91561 ctttgatgat ggaccaggag cgaccacaac gccgcagctt ctgcgaatct taaaagaaaa
    91621 aaacgtgcat gtcacttttt tcgtcttagg agaaaatacg gcgcagcatc ctgaaatcgt
    91681 gaagcagaca gctgaagcag ggcacgagat tggcaatcac acatacgatc atcagaatct
    91741 ggccactctt tctgcccagt cgatgacgga ggaagtgacg aaagcagaca ctgagatcaa
    91801 aaaaagtcac tggcaaaacc cccgcttttg ttcgtccgcc ctatggttct gtcacgaatg
    91861 taggagcaac gatcatccag cgaccgatca tcgaatggtc tgttgattca gaagattgga
    91921 agacaaggaa tcctgatttg attttgcaga agatccaagc aacagtatac gatgggtcaa
    91981 ttattttatt ccatgatatc tatcctgaaa cgattcgtgc cgttcctcaa gtgatcgatt
    92041 atctgaaaga gcaaggctat cgcatcacga cagttagcga tttattaggg catccaacgg
    92101 ctgtcgagaa ctattatggc agaaacgatc atcggccagt tcagtaagtg agacaagtat
    92161 ctttaataaa taacacattt taataagtag ttgaacacat aactacctta cttgcaaagg
    92221 cttaa
//
LOCUS       DARPZF010000006        91249 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.006, whole genome shotgun sequence.
ACCESSION   DARPZF010000006 DARPZF010000000
VERSION     DARPZF010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 91249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 91249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..91249
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.006"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            85..972
                     /locus_tag="SLE65_000599"
     CDS             85..972
                     /locus_tag="SLE65_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEI8447916.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="SLE65_000600"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="SLE65_000600"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEI8447917.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="SLE65_000601"
     CDS             2274..2720
                     /locus_tag="SLE65_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HEI8447918.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="SLE65_000602"
     CDS             2993..4345
                     /locus_tag="SLE65_000602"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HEI8447919.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="SLE65_000603"
     CDS             4516..4803
                     /locus_tag="SLE65_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447920.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            5029..5472
                     /locus_tag="SLE65_000604"
     CDS             5029..5472
                     /locus_tag="SLE65_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEI8447921.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5478..6662)
                     /locus_tag="SLE65_000605"
     CDS             complement(5478..6662)
                     /locus_tag="SLE65_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8447922.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGCAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6930..7628
                     /locus_tag="SLE65_000606"
     CDS             6930..7628
                     /locus_tag="SLE65_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEI8447923.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7635..8312
                     /gene="nth"
                     /locus_tag="SLE65_000607"
     CDS             7635..8312
                     /gene="nth"
                     /locus_tag="SLE65_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEI8447924.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8438..8971)
                     /locus_tag="SLE65_000608"
     CDS             complement(8438..8971)
                     /locus_tag="SLE65_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447925.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9268..11649)
                     /locus_tag="SLE65_000609"
     CDS             complement(9268..11649)
                     /locus_tag="SLE65_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEI8447926.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11639..12286)
                     /gene="recU"
                     /locus_tag="SLE65_000610"
     CDS             complement(11639..12286)
                     /gene="recU"
                     /locus_tag="SLE65_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEI8447927.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12350..12889
                     /locus_tag="SLE65_000611"
     CDS             12350..12889
                     /locus_tag="SLE65_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEI8447928.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12979..13398
                     /gene="gpsB"
                     /locus_tag="SLE65_000612"
     CDS             12979..13398
                     /gene="gpsB"
                     /locus_tag="SLE65_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEI8447929.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13420..13787
                     /gene="rnpB"
                     /locus_tag="SLE65_000613"
     ncRNA           13420..13787
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="SLE65_000613"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13996..15162
                     /locus_tag="SLE65_000614"
     CDS             13996..15162
                     /locus_tag="SLE65_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEI8447930.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15208..16704
                     /locus_tag="SLE65_000615"
     CDS             15208..16704
                     /locus_tag="SLE65_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HEI8447931.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16785..17468
                     /locus_tag="SLE65_000616"
     CDS             16785..17468
                     /locus_tag="SLE65_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEI8447932.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            18113..19303
                     /locus_tag="SLE65_000617"
     CDS             18113..19303
                     /locus_tag="SLE65_000617"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HEI8447933.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19405..20358
                     /locus_tag="SLE65_000618"
     CDS             19405..20358
                     /locus_tag="SLE65_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HEI8447934.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20427..21776
                     /locus_tag="SLE65_000619"
     CDS             20427..21776
                     /locus_tag="SLE65_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8447935.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21959..22282)
                     /locus_tag="SLE65_000620"
     CDS             complement(21959..22282)
                     /locus_tag="SLE65_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447936.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22411..23574
                     /locus_tag="SLE65_000621"
     CDS             22411..23574
                     /locus_tag="SLE65_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HEI8447937.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23644..24993
                     /locus_tag="SLE65_000622"
     CDS             23644..24993
                     /locus_tag="SLE65_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEI8447938.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(25038..25469)
                     /locus_tag="SLE65_000623"
     CDS             complement(25038..25469)
                     /locus_tag="SLE65_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8447939.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            25857..28499
                     /gene="alaS"
                     /locus_tag="SLE65_000624"
     CDS             25857..28499
                     /gene="alaS"
                     /locus_tag="SLE65_000624"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEI8447940.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28699..29295
                     /locus_tag="SLE65_000625"
     CDS             28699..29295
                     /locus_tag="SLE65_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEI8447941.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29417..30565
                     /locus_tag="SLE65_000626"
     CDS             29417..30565
                     /locus_tag="SLE65_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEI8447942.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30603..31016)
                     /locus_tag="SLE65_000627"
     CDS             complement(30603..31016)
                     /locus_tag="SLE65_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HEI8447943.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            31095..31526
                     /locus_tag="SLE65_000628"
     CDS             31095..31526
                     /locus_tag="SLE65_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEI8447944.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31625..31858)
                     /locus_tag="SLE65_000629"
     CDS             complement(31625..31858)
                     /locus_tag="SLE65_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HEI8447945.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            32041..33711
                     /locus_tag="SLE65_000630"
     CDS             32041..33711
                     /locus_tag="SLE65_000630"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEI8447946.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33858..34244
                     /locus_tag="SLE65_000631"
     CDS             33858..34244
                     /locus_tag="SLE65_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447947.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34231..34929
                     /locus_tag="SLE65_000632"
     CDS             34231..34929
                     /locus_tag="SLE65_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEI8447948.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34934..35398
                     /locus_tag="SLE65_000633"
     CDS             34934..35398
                     /locus_tag="SLE65_000633"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEI8447949.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35395..36306
                     /locus_tag="SLE65_000634"
     CDS             35395..36306
                     /locus_tag="SLE65_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEI8447950.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36541..37080
                     /gene="pyrR"
                     /locus_tag="SLE65_000635"
     CDS             36541..37080
                     /gene="pyrR"
                     /locus_tag="SLE65_000635"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEI8447951.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            37094..38377
                     /locus_tag="SLE65_000636"
     CDS             37094..38377
                     /locus_tag="SLE65_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEI8447952.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38390..39316
                     /locus_tag="SLE65_000637"
     CDS             38390..39316
                     /locus_tag="SLE65_000637"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEI8447953.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39335..40615
                     /locus_tag="SLE65_000638"
     CDS             39335..40615
                     /locus_tag="SLE65_000638"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEI8447954.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40620..41696
                     /gene="carA"
                     /locus_tag="SLE65_000639"
     CDS             40620..41696
                     /gene="carA"
                     /locus_tag="SLE65_000639"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEI8447955.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41701..44886
                     /gene="carB"
                     /locus_tag="SLE65_000640"
     CDS             41701..44886
                     /gene="carB"
                     /locus_tag="SLE65_000640"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEI8447956.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44940..45716
                     /locus_tag="SLE65_000641"
     CDS             44940..45716
                     /locus_tag="SLE65_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEI8447957.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45713..46645
                     /locus_tag="SLE65_000642"
     CDS             45713..46645
                     /locus_tag="SLE65_000642"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEI8447958.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46642..47358
                     /gene="pyrF"
                     /locus_tag="SLE65_000643"
     CDS             46642..47358
                     /gene="pyrF"
                     /locus_tag="SLE65_000643"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEI8447959.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47365..47994
                     /locus_tag="SLE65_000644"
     CDS             47365..47994
                     /locus_tag="SLE65_000644"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEI8447960.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47982..48296
                     /locus_tag="SLE65_000645"
     CDS             47982..48296
                     /locus_tag="SLE65_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447961.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48334..48975
                     /locus_tag="SLE65_000646"
     CDS             48334..48975
                     /locus_tag="SLE65_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEI8447962.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            49018..49710
                     /locus_tag="SLE65_000647"
     CDS             49018..49710
                     /locus_tag="SLE65_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HEI8447963.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            49707..50609
                     /locus_tag="SLE65_000648"
     CDS             49707..50609
                     /locus_tag="SLE65_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEI8447964.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50767..52473)
                     /gene="efbA"
                     /locus_tag="SLE65_000649"
     CDS             complement(50767..52473)
                     /gene="efbA"
                     /locus_tag="SLE65_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HEI8447965.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            52663..53286
                     /locus_tag="SLE65_000650"
     CDS             52663..53286
                     /locus_tag="SLE65_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447966.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            53736..54785
                     /locus_tag="SLE65_000651"
     CDS             53736..54785
                     /locus_tag="SLE65_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEI8447967.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            54782..55663
                     /locus_tag="SLE65_000652"
     CDS             54782..55663
                     /locus_tag="SLE65_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8447968.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            55666..56436
                     /locus_tag="SLE65_000653"
     CDS             55666..56436
                     /locus_tag="SLE65_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8447969.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            56715..57569
                     /gene="aroE"
                     /locus_tag="SLE65_000654"
     CDS             56715..57569
                     /gene="aroE"
                     /locus_tag="SLE65_000654"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEI8447970.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            57747..58910
                     /locus_tag="SLE65_000655"
     CDS             57747..58910
                     /locus_tag="SLE65_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEI8447971.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            59027..59437
                     /locus_tag="SLE65_000656"
     CDS             59027..59437
                     /locus_tag="SLE65_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEI8447972.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            59611..61839
                     /gene="topB"
                     /locus_tag="SLE65_000657"
     CDS             59611..61839
                     /gene="topB"
                     /locus_tag="SLE65_000657"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEI8447973.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGNLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            62010..62294
                     /locus_tag="SLE65_000658"
     CDS             62010..62294
                     /locus_tag="SLE65_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8447974.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            62454..62690
                     /locus_tag="SLE65_000659"
     CDS             62454..62690
                     /locus_tag="SLE65_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEI8447975.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            62687..63085
                     /locus_tag="SLE65_000660"
     CDS             62687..63085
                     /locus_tag="SLE65_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEI8447976.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(63752..64696)
                     /locus_tag="SLE65_000661"
     CDS             complement(63752..64696)
                     /locus_tag="SLE65_000661"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEI8447977.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(64992..65936)
                     /locus_tag="SLE65_000662"
     CDS             complement(64992..65936)
                     /locus_tag="SLE65_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8447978.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            66157..67371
                     /locus_tag="SLE65_000663"
     CDS             66157..67371
                     /locus_tag="SLE65_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8447979.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            67393..69408
                     /locus_tag="SLE65_000664"
     CDS             67393..69408
                     /locus_tag="SLE65_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HEI8447980.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(69491..70864)
                     /locus_tag="SLE65_000665"
     CDS             complement(69491..70864)
                     /locus_tag="SLE65_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEI8447981.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(70890..71174)
                     /locus_tag="SLE65_000666"
     CDS             complement(70890..71174)
                     /locus_tag="SLE65_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8447982.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(71176..73191)
                     /locus_tag="SLE65_000667"
     CDS             complement(71176..73191)
                     /locus_tag="SLE65_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEI8447983.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(73370..73675)
                     /locus_tag="SLE65_000668"
     CDS             complement(73370..73675)
                     /locus_tag="SLE65_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HEI8447984.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(73764..74795)
                     /locus_tag="SLE65_000669"
     CDS             complement(73764..74795)
                     /locus_tag="SLE65_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEI8447985.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            75002..75877
                     /locus_tag="SLE65_000670"
     CDS             75002..75877
                     /locus_tag="SLE65_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEI8447986.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(76029..76871)
                     /locus_tag="SLE65_000671"
     CDS             complement(76029..76871)
                     /locus_tag="SLE65_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEI8447987.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(76963..78840)
                     /locus_tag="SLE65_000672"
     CDS             complement(76963..78840)
                     /locus_tag="SLE65_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEI8447988.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(78837..80258)
                     /locus_tag="SLE65_000673"
     CDS             complement(78837..80258)
                     /locus_tag="SLE65_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEI8447989.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(80261..83650)
                     /locus_tag="SLE65_000674"
     CDS             complement(80261..83650)
                     /locus_tag="SLE65_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HEI8447990.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            complement(83904..84506)
                     /locus_tag="SLE65_000675"
                     /pseudo
     CDS             complement(83904..84506)
                     /locus_tag="SLE65_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(84512..85585)
                     /locus_tag="SLE65_000676"
     CDS             complement(84512..85585)
                     /locus_tag="SLE65_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8447991.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            85807..86481
                     /locus_tag="SLE65_000677"
     CDS             85807..86481
                     /locus_tag="SLE65_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8447992.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            86486..87826
                     /locus_tag="SLE65_000678"
     CDS             86486..87826
                     /locus_tag="SLE65_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEI8447993.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(87975..88961)
                     /locus_tag="SLE65_000679"
     CDS             complement(87975..88961)
                     /locus_tag="SLE65_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HEI8447994.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            89685..90716
                     /locus_tag="SLE65_000680"
     CDS             89685..90716
                     /locus_tag="SLE65_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEI8447995.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            90825..>91249
                     /locus_tag="SLE65_000681"
     CDS             90825..>91249
                     /locus_tag="SLE65_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HEI8447996.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
BASE COUNT        29191 a        16176 c        18593 g        27289 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt tttcttggtt tcagattggg ttttcctaca aaatattttt atctttgttg
     4981 aataggaaac aaaaaaacaa tataatgaaa gaaaaagaag gtgtagaaat ggataaaaga
     5041 caactgctaa tagaagaata tctggattta gctaatgaga ttattcatcg taataaacca
     5101 gaaatggaaa aagaatttgc aggatttact ctaaatgaac tagaagtgat tgaacatatc
     5161 gggaaaatcc ctgatcctaa cgtgacaaaa ttagcgaatg ctagttacat gactagagga
     5221 gccatcagta agctaacaaa aaaactgata gctagaggga tcataaacac ttatcaaagc
     5281 gaagagaata aaaaagaaat ctattttcaa ttgacgccaa tcggacaaaa aataaggaat
     5341 agacacgagc aactccatca aaaatgggta cagcgagatg ctactgtatt tgaaaatatg
     5401 tcaaaagaag aatttgacac agtatttcgt tttatcggtc gatacagaga atttatacga
     5461 agtagcaaat gaagctacta ttttttattg tagtgataat aggcaaaaat cataagcaaa
     5521 aatccgaata ccgtcggaag aaatggtgct gcagcataaa gctgtcctgc gattagcggg
     5581 ccgatgacgc gcgatagaga ttgtatactt tgggtaccgc ccattacaag accttgctgg
     5641 ttatctgaga cagaattgga tagttggcca ttgaatacag gagtaaaaat agaatcaccg
     5701 aaaccataac agataatccc aaataaaaac aaaatcggca gtagaagaat tccagataat
     5761 gtgatgaata gataggcgag gatttcactg aacatcccta ttcttgtgat ctgctgttct
     5821 gaaaattttt tgagcaatcg aggcataatg aacaattgcg agacagtatc caagattcca
     5881 atcaaagaga agcttaaacc aaccaaccca gccttccact gaaaggcgtc aatcgaaaat
     5941 tgagaaaaga tagattgaag agagccagct gccaaccaaa cagcacaacc tgctgtcaat
     6001 aaaggaataa cggatgaaat cttgaataat tgttgtaatt ggtgaaaagg tcttacatgg
     6061 gagaaactta aatctactga acgttttttt attggaaggc tttctagcat aaatgtgtag
     6121 ccataaacgg catttaagaa agtaaagagt gctccaataa atataggaac agaattcccc
     6181 aactcagcta atagaccccc tataatagga cccagcgttg ttcctatacc gactaaagca
     6241 cccatccatc caaaaacttt ggttctttca ttaggttccg tgatgtcggc aaagtaagca
     6301 tataaggtgg agatttctcc tgccgtcaat ccttcaatga tacgaccaag gaacaacatc
     6361 catatcgaat ttcctaaacc aaaaagcaaa tatccgatac ttgatcctaa taaactgata
     6421 ataaggatcg gatgacgccc aaaatgatca cttaagctac cgagaatggg ggcagataag
     6481 aaggcagcta gagcataaac agacatgagc aaagtgatat agaaagcttg ctgatgtatg
     6541 gagtgagaat aaggcagcgt taaaaacgga agtacaggac tgacgatagt aaatcctaat
     6601 ccagtgaata agacagagac gtatccaaaa actttagaat gtttatttgt gaaactgtac
     6661 atgtaaaaac tcctttatgc aataatgtta acttggaaac aaaaatagtg tatagtaatt
     6721 ttgtttcctt gtcaacattc taaggaacag cgaaatctac ttaatttatt tattccgaaa
     6781 agtgaagata cgcatcaaaa acatgaacaa acaaaaatca agtagacgac attgtaaatc
     6841 tgaccgatca gtgaagtaaa tagaaaagaa acctgttctt gcttcccatg ttttttttac
     6901 gtatactgtg attgagcgga ggagaaatca tgttgaattt agaaaattac ttaagcgctg
     6961 gacaaacagt catatctaat cttttactta aaaattatca taggatcggt ctacaatctg
     7021 aagaattttt atttgttcta cagttgcata tggcacagct tgaaggagat actttccctg
     7081 atttgcagat gattgctatg gatatgggaa tcaaacaaga tcagattttt caaatactgg
     7141 atcgtctcgt aacaaatgga tttatcaaga tagaaacgac gattgtcaac ggtaaaaaag
     7201 cagatcgata taatctttac cccatctatg atctattagg tgagtattta aaaacacaag
     7261 aaaaaaaata cgaagaaaaa acacaagaaa aagaaatcca gtcagtgtat caattatttg
     7321 aacaagaatt tggacgcccg ctttcttcga tcgagttcca gcggatcgga caatggctag
     7381 aagaagacca ttatcagccg gaaattttga agctagcact gcgggaagcc gtattaaatc
     7441 aggcttatag ttttaattac gttgaccgca ttttgctatc gtgggaaaga aaaaatctac
     7501 gtacaaaaca acaagtggaa gaagaccaaa aacgaagaaa acagcagctt cttcaaagag
     7561 aagtagaaca gtcagctcaa caagaagaat tgccgaaagt ctcactgaaa aattggttgg
     7621 aggagtagcg gaatatgtta agcaaacaaa aaacaatgga agctctagaa acgatgtatg
     7681 gaatgtttcc cgaagcacat ggagaactca agcacaataa tccatttgag ttattgattg
     7741 cagtgatctt aagtgcccag gcgacagatg tatcagtgaa taaagcaacg ccagatttgt
     7801 ttgcctcttt tccgacaccc gatgcgttag cagaagcttc aatcgatgaa atcattctta
     7861 aaataaaaac gattggtttg tatcgaaata aagcaaaaaa catcaaagcg tgtgcacagc
     7921 agctgattga acgtttcgat gggcaagtgc caacgtcaag agaagaattg atgtctcttc
     7981 ctggtgtagg cagaaagaca gcaaatgtcg tattggggga tgcattcggg ataccagcaa
     8041 tcgcagtaga tacccacgtg gaacgtgtct caaaacgcct gaggatctgc aaactagatg
     8101 ctacggtcat ggaagtagaa gaaacactga tgcggaaagt accacaagaa ttatgggtaa
     8161 agacacatca tacactgatt ttttttggta gatatcattg cacggcaaga aatcccaagt
     8221 gcgaggtatg tcctttgcta tcaatatgtc aagatgggaa aaatcggatg cgtctaaaag
     8281 aaaaggcgct aaaaaagaaa ccacgcctgt agacgtggtt tctttaattg caaataaatg
     8341 tatgaattat cttgttatta tggagaaaag ctgtttcgtt tatctttttt gcatgaaaaa
     8401 gtaaatgtac atactcagta gctaggatgg taacttatta caatttattg cgataaaaat
     8461 aaaagttgtt atttttattg ggaaaatacc cgatgtagaa aataatgcct tccaatatac
     8521 ctataaaata agtccagtat tccaaaggat tatataaata agtgacgtat ctatctaaag
     8581 gtgtaataaa aatgataagt gataataaaa aaataccatt tataactaaa cataaactaa
     8641 tggatttggg cggtttcagg ctcatcagaa aaatatagat tctggtgaac aacaaccata
     8701 aaaaagtgag aatcattgca tgagagcttc tttccataaa ttttccttta agagtagtgc
     8761 ttaaaagtac agaaaaaata ataaatgcaa ggataggagc aattaaagta aatttattta
     8821 ataataaaca aaatttttca gcttttttat tcttggaata acgaggtatt gttttcgata
     8881 aaaaaagatg gtgcagacaa attatgataa ttaagcatac tatcagataa ctcaaaatga
     8941 agccttcttt caaaaaatta ttcaaaacca tatattgtat tttttatttg ataataacaa
     9001 tgggattatt aagaagtggc actaaataaa agactagtgt gtatttagcc gatttaatta
     9061 taaacaagta aatggataaa gtatatgtaa tgataaaaga aaaatggatt ttctaatttt
     9121 taagctaaat gttagatcac acatgtatat gctggatagt cttataaaaa atcatgtaat
     9181 acagcttggt acatgatttt tatttgtagc tgttttttac atagacacaa aaaagaaacc
     9241 acgcttgtag acgtggtttc ttttttacta tctgtttcca gaagctgagg tgctgctgga
     9301 tggtgtatgg tcatttgcag catccgctcc gctagttgct ggctcactgg aagaagcagg
     9361 aggagcagat gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga
     9421 agacgctggc tcgcttgttt ctgctgtcgt gctttctttt gaggactcag cagttgattc
     9481 gctttgacta gtagagctag agctttgagt cgttgtctct gttgttgagc ttccaggagt
     9541 ctggacatag ctggaagatg gaatagttgt tgatggtgta attgcattcg atctagctgt
     9601 atattgatct ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg gcatctccca
     9661 gtctgtattt gtcacgttag ctgaaacata ctgcataagc tcgcgataaa catcagaggc
     9721 tacgtgtgac gattctgaag tgacaggtgt cattttttta ttgtaacctg tccacacgga
     9781 aatcgaataa tttggcgtat agcccgcaaa taggatatct ggatacaccc cagaagaaat
     9841 accaagtttt gcatactcgt catctgtgta attggatgtt ccggtcttac cggcttgata
     9901 taacccagcg atttgcgcat tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc
     9961 tgtgatcata taagctgttt ctggagacat ggctgttttt ccatctggct cataagtttc
    10021 ttctgttccg tcttggaaga cgattttatt aacatattga ggtttgtaat aagtccctcc
    10081 attggcgaaa gccgcatagg ctgctgccat ttttaaggaa gaagctccgt attttgtccc
    10141 atcttgttct tccgtattac tagagatcgc attcgattga tggatcgtac tgtattcgat
    10201 cccaagattt tttaagaaag aagccacttt atctgaaccg acttcattga ataatttgac
    10261 tgctggaaca ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg
    10321 attatcccag tttcctacag gagtcgaagt cccttcatag ttatacggtg cgtcagtaat
    10381 agtttttcca gtagaatatt tcaaatattc aaaagctggt ccgtaatctg tgacaggttt
    10441 catcgtagaa ccaaaatcac gggaagtatt cactgctaag ttgttgccta aagttacgtc
    10501 ttctgcgatg tgacgtccgc caatctgggc ttttactttc ccggtattgg tgtcgataag
    10561 ggtggaggca acttgcatct cgtcgtctgg gtaagagaca tactgatccg tgttgacgat
    10621 atcatatagt ttcttttggg cgtccagatc caaattcgta taaatctcta aaccgtctgt
    10681 gtagacattc ttatctgttt tttcttgtac ttcattgatg acttctttga cataattatc
    10741 gacgatctta gtattgtcat cggattgagt tagttcttgc agaccatccg ttaccggtac
    10801 attaacagct tgatcatatt ctgtttgaga gattttttcg ttttgaagca tcgtatacaa
    10861 aacagtatct cgtcttttct tcgcctgatc tggataaaca taaggatcat aggcggaagg
    10921 ggcttgaggc atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt
    10981 accaaagtac atctcagaag ctgtctccat cccgtacaag ccgtttgaca tatacacttt
    11041 atttacgtag taggtcaaga tctcttgttt cgattttttt tgttccaatc ttacagccat
    11101 ccacgcttct tgggccttgc gtttcagagt ctgatcctcg gcactggtgg agaagaagga
    11161 aagtttgatc aattgctgtg tcaaagtact tccgccttgc agtccgccag aggtaaagtt
    11221 agagagggca gaaccgatga tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg
    11281 atcttctacc gacacgatcg catcttctaa tgttttcggt aattcattcg cagaaatttt
    11341 ttcacgcttt tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat atagtttgga
    11401 agatacggta gcgtctaatt ttttatccgt caattcgggc gcatcttttg cgtaatacca
    11461 gaaaagtcct acacctgcta aaaagaggat acagaaaaat gagagtattc ctaaaaggat
    11521 cttgataaat aatccttttt tatgtgttcc agaggacttt ccagaacctt tgccagaatt
    11581 cttcttcaca ctctttttag gagtaggctg tttctgtcgt ctagagcttc tagtttgttc
    11641 atttgccatt cttgctttct ccttcaatag ataatgttga taaatagaag tcaaccgcgt
    11701 ccaaataagg aatccgcgga gaaataccag ttttgatctc tattcctagt tcttcgatca
    11761 aagataaagg tagtgatttg cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat
    11821 gaacactatt caaataaaaa cagcgcttca aagacgaaaa ccataacaag acaaagcaga
    11881 ccccattttg ttcgaggcat gctttcatat gttcgatttg atgggcatgg aagtttttaa
    11941 agggaaaaga tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat
    12001 agacgccatt atagtctgta gttgaggctt gggtaaagta ggcttccttg atcacagcag
    12061 cacttctctt aggatagtct actttcacga tttggatagg ggtaggcttt ttatggataa
    12121 ccgccaaccc gcgggaaaga taatatttat tactttcatt gattgcttct tcaaagcgca
    12181 tcccccgatt gccgaattca gtgatctgat ttcttttttc ttgaattttt tcgacgggag
    12241 aggcattctt ataataaggt tggccatttg gatagcgcaa taccatcttt aatcacactc
    12301 ctaggccaca ttatagcaaa aaagcggata gaaagaaaag gaatctgaga tggataagtc
    12361 aaaagtaatc tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta aagaaaatga
    12421 tcctaaaatc caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga
    12481 agggctggaa tgggtacttg tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat
    12541 agtagcggaa ttgaaagaag aatatccgga actatctctt ggtattttgt atcctttttc
    12601 tgattttggt aataactgga atgaagggaa ccaagaaaaa aaacaattag cagaacaatt
    12661 agcagattat gtcgaagctg ttagccatca accctaccaa tcacctagtc agctaaagaa
    12721 tcacactcgt tttatacttg agcatacagt gggctgtctg ctgatctatg atgaagaatt
    12781 ccctggaaaa acgaagtatt tttttgaaga tgcacagaat taccaagcag atcatcccta
    12841 cgaaattcgg ctgatcagta tggacgatct tcaaaatttt agtgaataat cgatattgtg
    12901 tttgatttat caactttttt cctatacaat gaaaaaggta gaaatgttat tacgtaaatg
    12961 aaaactagag gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat tttacaacaa
    13021 gaattcaaaa caaaaatgcg cggctatgat cccgttgaag ttgatgaatt cttagacaat
    13081 atcatcaaag attatgaaac ttacagcaaa gaactccttg ctttacaaga agaaaacgat
    13141 cgattgagtg caaaagtagc tcaattatct aaaactcaag gagcagctca aacacgcgtg
    13201 caacaaacag aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg
    13261 tcaaatcttg aacgtgaagt atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa
    13321 ccagcacaac ctaatccaaa taactacaca aatgcagaca caagcttaga tgataatgaa
    13381 aaaacacgtc aattttaatt tttgattaat gaatttgcgg ttttcgggta atcgcggtct
    13441 gacttgatca ggctgaggaa agtccatgct cgcacaggct gtgatgcctg tagtgttcgt
    13501 gcttagcgaa accataagct aaggtactct ttggagtaac ggcaggaaaa caagctaagg
    13561 cttcggctat gcttaagtat ccttgaaagt gccacagtga cgaagcggct ggggaaaccc
    13621 atccggtgga acgcggtaaa cccctcgagc gagcaaccca aacaatggta ggggcgcttt
    13681 ttgtctggaa gaagaacagg acaaaaaggc agtataactg cagatagatg gttaccgctt
    13741 tgttttttct ccctggaaaa gcaaagtaca gaacatggct tatagaaaac cgcaaacatc
    13801 agggaattag gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac atttgaaagc
    13861 tatttttcaa tacttcagat gaatcgttct tattacaaaa caaacttttg tatcaccggt
    13921 tattcggaat ttgagtaaaa gtgtggggta ggactgatgt cccacctcct ttttttataa
    13981 ataaggagat tgtgtatgga aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc
    14041 gggctagaag cactggttgg taaagaatta agagatcttg gaatcgaatg ccaagttgag
    14101 aacggacgtg cacgttttga aggaacaatg gaaacgatcg ctacagctaa tttatggtta
    14161 cgtacagcag atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa
    14221 ttgtttgaaa acgtaaaagc attgccttgg gaagattttc ttccactaga tgcagctttt
    14281 cctgtagctg gaaaatcgat caagtcgaaa ctatatagca cacctgattg ccaagcgatc
    14341 acaaaaaaag caatcgttga acgtctccgt acctattatc accgtccagc ttctgtacca
    14401 ctgacggaaa ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg
    14461 gtaactctgg atacgacagg accaagttta ttcaaacgtg gttatcgctt agaaaaaggt
    14521 ggagcaccat tgaaagaaaa catggcagca gcacttatta tgttgacaaa ttggcgaaaa
    14581 gaccgtccat tttatgatcc tgtatgtggt tcaggtacgc tttgtattga agcagcctta
    14641 ataggccata atatcgcacc aggattcaat cgtgagtttg cttgcgaatc ttgggattgg
    14701 ttcagtcaag aaatcatgga aaatgttcga tcagcagccg aagaaaaagc agattatgat
    14761 attgaattag atattactgg ttcagatatc aatggacgga tgattgaaat tgccaaagcc
    14821 aatgcagaag aaatcggatt aggctcttcg attaccttta agcaacaagc agtcaaagac
    14881 ttcaaaacgg ataaagaata cggggtcatc gtggctaatc cgccttacgg agaacgtcta
    14941 ggagaagaag aaactgttcg gaaattatat aaagaaatgg gcgatgtatt ccgtccatta
    15001 aaaacatgga gtaaatatat cttgactagc gacttagcgt ttgaggaatt ttacggacaa
    15061 aaagcaacca aaaaaagaaa attgtacaat ggtgcattgc gtacggatct attccagtat
    15121 tggggaactc gtccgcctag aaaaaaagag aaagacgaat aatcttacta attgattcat
    15181 tcaattggat gtttggagga atagggaatg aaagaaaaag agtttttaca agaagtaaaa
    15241 gaaatcaatc ttctacaaca agctttagga atcctcgatt gggatacaca aacaggtatg
    15301 cctgaaaaag ctagtgcata ccgaagtgaa gtagacagct atctttacag catttatttt
    15361 tcaaaaaaaa tcggtccaaa aatcaaagaa gccattcgct atttttctga acatccggaa
    15421 gaattgtcgg aagttggaac tgccgttttt gccaaagtaa aagaagagta tgatttggaa
    15481 catcgcgtac cggaagatct tatgagaaaa tatacagctg ccgtttcttc agcacacgga
    15541 caatggcaaa aagctagaga aacacaacaa ttttctgatt ttcaacacgc attgaatcaa
    15601 aatattgaat taacaaaaca gttgatacct tactggagaa aagatgaaaa gacgaattat
    15661 gatgttttgc tgaatcaata cgaacccggg atgactgtcg aaatccttga taaggtattt
    15721 gatcagctta aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa agggactgaa
    15781 cctgaaacag actttttaaa tcggagaatg acgaaaaaac aacagaagag atttgtagtg
    15841 aaagtaatcg aacaacttgg ttatgatttt agtcgtggtc gtttagatga cactgtccac
    15901 ccatttatga ctggaattaa tccgaatgat gcacgaatca cgacacgatg gaacgaaaca
    15961 gatttcaaaa tggctgtttt tggagtgatc cacgaggctg gtcatggtat gtatgaacaa
    16021 gacatcgatg ataaatatgc gtatacaccg gtttatgaag gtacatcaat gggtatccat
    16081 gaatcacaat cgttgtttaa cgagatcatt attggaagta gtcgcagctt ctggaaaaag
    16141 caatatcctt tctttcaaga atgtgcagaa ggaacattcg atgatattcc ttttgacaaa
    16201 ttttatcgtt cattgaacca tacaaaatca agtttggttc gtatcgaggc agacagtttg
    16261 acttaccctc tccatatcat cattcgttat gaaatcgaaa aaatgatttt caatgaaggg
    16321 gtagatgttg ctgaactacc tgaaatatgg aatcaaaaat atgaagagta tctgggaata
    16381 cgaccaacaa atgatgtgga aggcatccta caagacgttc attggtcagg tgcaagcttt
    16441 ggttattttc cctcttatgc attagggtac atgtatgcgg cacaattact tcattctttg
    16501 cagcaagaaa tagatgtgga aaatgttcta gcgtcagacg attattctcc aatcaaaaac
    16561 tggatgtcag agcatatcca tcaatatggt gcatctagaa aaccaaatca attaatcatg
    16621 gatgcaacac atgaaccgct taatccgcaa tacctgatcg actatatgaa agacctgtat
    16681 tttaatgtat atcaggtaaa ataaaataca atttacaaag atagctgaaa ttcatctaat
    16741 ctatagatgt tttcagctat ttacttaaga aagaagtgga acgaatggat aaattacaag
    16801 tgatcgctga ttatagtatg gaccaattag cgcatgatca aacaggacat gggagcgatc
    16861 ataccaaaag agttgtcaag ttagctgaaa aaattttgga gacggaaccg caggcagacc
    16921 gctttgtgac gcttgcagca gcttacctac atgatacgat tgatgataaa gtcgttaaaa
    16981 atgagaacga ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca atagtagagg
    17041 aacagatctc gatgattttt tccattatcg aaaatatgtc cttttctaaa aatctctctg
    17101 aagcggccga actatctctg gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat
    17161 taggagcaat cggcattttg cgtactgctt atttcggcgg tggacatggg cacccgattt
    17221 ttgatcctga actgtatccg caaacattca aggacaaaga aaattaccga aaaggcacga
    17281 cagtgatcaa tcatttttat gaaaaactgt tcttgctgtc tgataaaatg aatactgatt
    17341 acggatatga agaagccaaa cgaagagaaa ccttcatgcg tgaattctta gaagaatttt
    17401 ttctggaatg gtctattgac gatgaaaatt ttactccaga caattggatc aaaaataaca
    17461 aaaaatgatg gaggttgtga cagaagtggt cagctccaag atatttcgga tcattttccg
    17521 taaaagttac ttctggaaca ctgtttacca agaggtcgtg agcctgccgt tcagctccga
    17581 gtcacaagga acaatttcaa aaaatagctt ctcgtgtttg atgaatattg taacttgtga
    17641 ttcggaattg gcaggagaac accgtttatt cggaagaata ggactgtgac aagacttttg
    17701 tcacagtcct tttttcgaat tcaacaagta aaacttttaa gaaatattca gagagtaaaa
    17761 ttaaaaattg ctgataaacg aagatggaaa ttttatgtat ttttattggt ctatgcaata
    17821 aataaattaa atattcagaa tacaattgat tttaacgaaa gggcttctat caatggttgt
    17881 gttgtattta tctgcccagg tagagtaaaa tagatcatta tctaaaaggt aattgttcat
    17941 actatataag tcatttgaaa gtaaaaagat actgtaaata aaaaatgtgg ttaaataatt
    18001 ctcataatca gtgtaagcgt tatcaaaaat atagcatact tgctttgtag atgaatgaca
    18061 cgatatatgt ttggtatgtt ctgcaagaca gatgaatatg gaggtggaga caatgtcttc
    18121 caaagaacta acaatgtatt tagagaaaga attggatcaa ctgaaagaaa aggggttata
    18181 caatacgatc gacatactag aaagtgaaaa tggtgcttgt atcatcgtag acggaaaaaa
    18241 gatgatcaat ctagcatcca acaattatct tggatttgcc aatcgcgaag aattgaaaaa
    18301 agcatgtatt gaagcaaccg aaacttatgg tgtaggagca ggagcagtcc gaacgatcaa
    18361 tggttcgctg aaaatccatc agcaattaga agaaaaaatc gcagaattca aagggacaga
    18421 agcagcaatc gcctttcaat ctggattcaa ctgcaatatg ggcgctatct ctgcagtaat
    18481 gacaaaagaa gatgctatct tatcggatga attaaaccat gcatctatta ttgacggttg
    18541 ccgcttatcc ggagcaaaaa tcatccgaat taaacatcaa gatatgaaag accttgagaa
    18601 aaaagcaaag gaagcgatag aaagtaagaa atataaaaaa atcatgtata tcacagatgg
    18661 tgttttctcc atggatggag acattgcacg attgccggaa attattccga ttgttgaaaa
    18721 atatggactg atcacctacg tcgatgatgc gcacggctca ggcgtaactg gaaaaggtgc
    18781 aggaaccgtc aagcattttg gattaagcga caaaatcgat atgcaaatgg gcacgttatc
    18841 gaaagctata ggtgttgttg ggggttatgt agctggatcg aaaacactaa tcgactggtt
    18901 gaaagctaga agtcggccat tcctattttc tacttcgcta actccaggtg cagctgcagc
    18961 tgcattggct tcgattactt tgatgcaaga acatccggaa cttgtcgaaa aagtttggga
    19021 aaatgctaat tattttaaag aagaattgaa aaaagtaggc tataacatcg gtatgtctga
    19081 aacacctatt actccagtca ttttgggaga cgaaaaagtg actcagactt tctctaagaa
    19141 gctgatcgaa catgggattt atgctaaacc aatcgtttat ccaactgtgc ctcttgggac
    19201 aggcaggatc agaaatatgc cgactgcgga acatacgagg gaaatgcttg atgaagcagt
    19261 agcagtttat caaaaaatag gaaaagaaat ggaaattatt taactaaatt tagttttttc
    19321 gtctatttaa aattagagaa catgttcacg catatattgt taatcatctg aagatagtag
    19381 taaaaaagat cagggaggat catcatgaaa aaagtattgg tgacaggatg tttaggacaa
    19441 attggttcag agttgatcac acggctacgt caagaactag gcagtgaaaa tgtcattgcg
    19501 acagatatac gcatgcctga agtcattgag aaaaacgata tctttgagat cctagatgta
    19561 atggattacg aaaaaatgcg cagcatagca gaacaatatc aagtggacac attgattcat
    19621 ttggctgctc ttttgtcagc tgttgcagaa gcaaaaccac aattagcctg gaatttgaac
    19681 gtgactgggc tggtcaatgc attggaagtc gctagagaat tccagctgaa attttttacg
    19741 ccaagttcaa tcggcgcgtt tggtccaaat actccaaaag atcatacccc acaagatact
    19801 cttcagcgtc ctacaaccat gtatggggta acgaaggtag ctggagaact actatgtgat
    19861 tattattatg tgaaatatgg cgtagatact cgtggtgtcc gtttccctgg attgatttct
    19921 tatgcaacct tgccaggagg cggtacgaca gactacgcag tcgatattta ttattcagca
    19981 atcaaagaag gaaagtacac tagtttcatt gatcaaggta catcaatgga tatgatgtat
    20041 atgccagatg cgatcgatgc cattataaaa ctcatgaatg cagatcctga tcgattggtt
    20101 catcgaaatg ccttcaatat atcggcgatg tcttttgacc cggaagagat caaagcatct
    20161 attcaaaaaa tcataccaga ttttgaaatg gattatgatg tggatcctgt acgtcagtca
    20221 atagcagaat cttggccaaa ttcactagat gtttcttgtg cgcaagagga atggggcttt
    20281 tcgccgaaat acgacttaga tgtgatgaca aaggatatgt tggaaaaact gaaagaaaaa
    20341 ttggtagaga cggtataaaa caagaaccac atccaaaaag ttttttatac ttttgggatt
    20401 ggctatggta tgaaagggga caagggatgg aagaatatca agccacgcca gtaaaagaag
    20461 taaaaataga aaatgaatta aaacgtacga tgggattttt tactgcttta tcgactgtta
    20521 tgggcacagt gatcggtgca ggggtatttt ttaaagccgc aagcgtagca gaagttacag
    20581 gatccgccag tttgcatatg ttttcttggt ttctcggtgg tatgatttct gtctgtgcag
    20641 gactaacagg agctgaactg gcagctgcta ttccagaaac aggagggatg attaaatata
    20701 tcgaacggat ttacggaaat acagcagctt ttttattggg ctgggcgcaa gtcgtgattt
    20761 attttccagc aaatgtagca gccttgtcga tcattttcgg tacacagttc gtcaatctat
    20821 ttggtctttc ccagtcaatg attgttcccg tagctgttac agctgctgta tcgatcctgt
    20881 tgatcaattt tttaggttct aaagctggag gggcttttca gtcgattacg cttgtctgca
    20941 agcttattcc tttgtttgtg atcgtcattt tcggtttgtt ccgacaagaa ggagtagact
    21001 tccaactgtt tccgatccaa gcaggagaaa atctttcatt tttctcagcc ttgggagcgg
    21061 gcttgctagc aacgatgttc gcatacgacg gttggataca cgtaggaaat atttcgggag
    21121 aattgaaaaa gccggcgaaa gatttgccaa aagcaatttc tttaggaatc atcggaatca
    21181 tgatcgttta tttattagta aatgcggtgt tcttaagaac cgcatctatc gacggagtcg
    21241 caggaaacag caatgcggca agtgacgttg caaaaatgat ttttggcggc ttcggtggaa
    21301 gactggtcac agttggtatc ttgatttctg tttatggaac catcaatggc tataccctta
    21361 ctggaatgcg tctcccttat gttatggcaa aagaaaacaa cctgcctttt agcaagctct
    21421 ttgctaaact tcatgataaa actaaagttc ctgtagccgc aggtatctta gagctagtca
    21481 tcgctattgg catgatgatg atcggtggtt ttgatacact aacggatatg ctgatctttg
    21541 tcatttggat tttttatacg atggtctttg ttggtgtcat tcttcttcgt aaaaaagaac
    21601 ctgatttgtt tcgaccatac aaagttccaa tgtatccgtt tattccacta gtagcaatca
    21661 ttggagggac ttttatcgta tcaagcacgc ttatcactca gaccttttta gcttcgatgg
    21721 ggatagtatt gacacttgct ggtatcccga tttatctcta tttaaaacgt agatagctaa
    21781 aacattcgaa ttttattaga actgcacttc tctgccaaac aaaatatttt atttaaatga
    21841 ggagtacgtg gaagaaatgt caaaagtact cgttaatttt gatcacgtaa atgtcgtttt
    21901 gtctacgatg aaatagcaaa gtaaaagaca gaaatcgggc tcaaccgatt tctgtctttt
    21961 actttgattt gcgtaactga actattcggc gtacgccgcg ataaatattt aataaaacca
    22021 agcaaccaga aatgaaaatg ggaagccaaa tcagatagac agggtagcca agcactttag
    22081 acaaagcatg tggagtcatt ttatccattt caagaagtgc ttgctgccaa gtctgaagat
    22141 tgaagactag catgaaaccc gaaataatca ggagaataaa tcctaaataa tgaattgtag
    22201 ttctttttct tacataagcg atcgtagcat aaaggaacag taaaaaaata ggtacgccaa
    22261 aaacaaagta catattcagc atctcgacac cccctttgtg tttatcttac tttactttga
    22321 aagaaatgag aaataatagc ctcgttactt gcttgaaaca gcaaaggact gctaagataa
    22381 gagagataca aagaatcaag gaggagtcat atggcaagtt atatcgaacc gattcgtttt
    22441 gcgctgattg tttttccatt tttagcctta gcgatctcat ctgttttttt tatttatgaa
    22501 tatcgaaagt atggaacatt tctagtaaca agggcagtta ttttgtattc tttcgttttt
    22561 tatttattgt gtgcgtattt tttggtgatc ttaccacttc cggcaaagga gacggttgcc
    22621 caaatgacag ggccaaagat ggagctgcat ttatttgctt catggcaaca tttcagagac
    22681 aacacggtat tggtcttgtc tgaacctagt acctacctgc cggcaatgaa gcagagtgta
    22741 tttttggaac cagcttttaa tgttttatta ctcataccat ttggcattta tttaagatat
    22801 tatttccggc tttcttttat gaaaacgatg attgctagtt tctgcctttc tctatttttt
    22861 gaattgacgc agctaagtgg actttatttt atctacccaa gaccataccg cttatttgat
    22921 gtgaatgatt tagtgacaaa tacattgggt ggaatcattg gttttgtcgt tacgccgtta
    22981 tttacattta tgcttcctac aagaagacga atggatgaac tttcttatga aaaaggaaag
    23041 actgtctcat tgactcgacg cttggtcgct tatttgatcg actggacatt tttatctctt
    23101 attaatttgg tagcggcgat tttctttaaa attgcgttcg attcaggggc agttacttct
    23161 catatctggt ggcttttatt agaagtaggg gtatacttta tgattgtacc gtttataacc
    23221 aatggatgga cacttggcaa aaaaattgtg cgtatccgtt tggtggaaga agaccgcgaa
    23281 cgaatttctt taaaagcatt gatgatccgc tacgggtatc tgtactttct tttttatggt
    23341 ttaagctggt tggggcagtt gcttcagcaa atcatgaatt cgacaacgaa tacggtgttg
    23401 cagatgagtg cagtattcat ttctctcggt gtcttgttac tacaaggtat ttttatttta
    23461 aatatcttgc tatcattttt gagaaaaaaa cggattctgt tttatgaaaa agctagtcac
    23521 acatatactg ttagcacgat tggccaaaca aaggatgatg attctcgaaa ttagctgagc
    23581 aaaaacgctt tgtctgtgtt ataatgccaa agtcgtgata atttaaagag aagaggtgca
    23641 cgaatgaata attttgatat attccgcttc aaaccgttta tcaatgaagc gttaaccgca
    23701 aagggcttca aacagcccac agaggtccag gaacgtttga ttcctttaat tgcaaaagga
    23761 aaaaatatca ttgggcaatc tcaaactggt acaggaaaaa cacatacgtt tttgttgcct
    23821 ttgtttgaaa aaatcaatgc agaaaaagag gaagtacaag ttgttattac agctccaagt
    23881 agggaactag ctgcacagat ctatgaagca gctacacaaa tcgctaaatt ttctacaccg
    23941 gagatccgtg tctcgaattt tgtcggcggt acagacaaac agcgtcaatt aaatcgtctg
    24001 catcaccaac agccacaggt tgtagtaggc acgcctggta gaatattaga catgatgaat
    24061 gaacaagcgc tgaagattca caccgcattt gcatttgttg tcgatgaagc ggatatgaca
    24121 ttggatatgg gttttttaaa tgaagtagac caaattgcaa gtcgattacc agaaaagctg
    24181 cagtttttag ttttttctgc cactattcca gaaaaacttc gtccattctt acgaaaatac
    24241 atggaaaatc caatcattga agaaatcaaa ccaaaagcag ttatttctga agacattgaa
    24301 aattggctga tttcaacaaa aggtaaagat gagaatcaaa tgatttatca actgctgaca
    24361 attggtcatc cttatttagc aatcgtattt gccaatacaa aacagcatgt ggatgaaatt
    24421 gccgattact tgaaaaacca aggcttgaaa gtagcaaaga ttcatggaga catcacccca
    24481 agagagagaa aacgagtgat gcgacaagta cagaatctgg agtatcaata tgttgtagcg
    24541 actgatttag ctgctagagg gatcgatatc gaaggtgtct ctcatgttat taatgcagaa
    24601 attccagaag atctagactt ctttatccat cgtgtcggac gtactggacg taatggctta
    24661 aaaggaacgg ccattacgtt atattcgcca aatgatgagc aagccattga tgcgatagaa
    24721 aaattgggcg tctcatttga accaaaagaa atcaaaaacg gggaaatcgt caaaacatac
    24781 gatcgtaata gacgtgccaa acgagaaaaa tcaaaagatg tattagatcc cacgctgatt
    24841 ggtcttgtga agaagaaaaa gaaaaagatc aagcctggtt ataagaaaaa aatcgattgg
    24901 gcaattgcag aaaaaaataa aaaagaacgc aaaatcgaac gcagacagca aagccgtact
    24961 gctcgtaaaa ataagaaaaa ttcacataaa taaaaaacaa gaggttgtga caaaaggcgt
    25021 gtcacaatct cttgttttta agctagactt tttttcattc cgatacaaag tacttcatct
    25081 tcaataaaag gttctgtgca agtatgatac ccttgttttt cataaaaatc tacagccgtc
    25141 atttcagcta ctacataact agtctgacaa ccttctgaaa ccgcccgttt ttcagcagct
    25201 tcaagcaact gaccgcctaa cccttttcct cggtattctt ttgctacgca aaatcgttcc
    25261 ggcttgaagc aagtaggtgt tttcttttca taacgcaaag tagctactgg tcttttttga
    25321 tcaagaaata gataataggt ttgttgcggg atatcttttc cgtcgaattc tagttctgca
    25381 ggaatccctt gttctaatac aaaaacttga tatctcaaaa agcagctagc tgcgcgtatc
    25441 cattcatccg ctccaactat ttttttcatc atattcctcc ttgtcatgaa tagcagagat
    25501 gtattgattc ctttattctt atcgtaccaa aaatcgtgga gtatgaccaa aaggaaatga
    25561 aaataaaaat tgagatattg acagtgatca atagaatgcg tatactaaat aagtacgaaa
    25621 aggatatgat ttgtttttta agactcacag aaaattcttt cttggctgaa aaaagaatag
    25681 tcactaatca aattgctccc tttttctatt ttggtagaaa taccgacgca gctcagcgtt
    25741 atcgagttta agaggtaatg attacacatc attgcaatca aggtggtacc gcgagttttc
    25801 gtccttggct gtgatggtgt ttttttgtat ttaatttata gaaagcaggt aatgacatga
    25861 aacaattaag tagtgcacaa gttcgacaaa tgtttcttga tttcttccaa tctaaaggac
    25921 atacgattga acctagtgcg tctttgatcc ccgtgaacga tccaacctta ttgtggatca
    25981 actctggtgt tgcaacattg aaaaaatatt ttgatggttc agttgtgcca gaaaatccaa
    26041 gaatcacaaa tgcccaaaaa tctattcgaa caaatgatat cgaaaatgtc ggtaaaacag
    26101 cacggcacca tacgatgttt gagatgctgg gtaatttttc gattggtgac tatttcaaaa
    26161 atgaagccat ccactgggca tgggaatttt tgactgatcc aaaatggatg gcattcgatc
    26221 cagaaaaact ttatgtaaca gtttatccaa aagatacaga agcaaaacgc atctggcatg
    26281 aagaagttgg cctgccacta gatcacatta ttgatgtaga agacaacttc tgggatatcg
    26341 gtgcaggccc atgtggtccg gatacggaaa ttttctatga ccgtggagaa gcttataacg
    26401 atttagcaga agacgatcct gaaaactatc caggaggaga aaatgaacgt tatttagaaa
    26461 tctggaactt agtattttca gaattcaacc ataagcctga taacacattt gaaccacttc
    26521 ctcataaaaa cattgatacg gggatgggat tggaacgcat ggtctcaatc gttcaagatg
    26581 cgtcaacgaa ctttgagaca gacttgttta tgcctattat ccacgccgta gaaaagctaa
    26641 gcaaacaagt aaaatatggt gaaaacccag taacagatat ttcttacaaa gtaatcgcag
    26701 atcatattcg cgccctttca tttgctattg gcgacggtgc attgccatcg aatgaaggga
    26761 gagggtatgt cttacgccgt ttgcttcgtc gtgctgtcat gcatgggaaa aaattaggta
    26821 ttgaacaagc attcttatat cgtttagtcc ctgttgttgg ggaaatcatg gtaagttatt
    26881 atcctgaagt acttcaacaa aaagaattta ttgaaaaagt tatccgtaca gaagaagaac
    26941 gtttcaatga aacaatcaat gaaggtttgg aaatcttaaa tcaagtgatc caagaagtaa
    27001 aaaacgaaaa cgggacgact ctagcaggaa aagacatctt caaactatac gacacatatg
    27061 gcttcccggt agaattaacg gaagaggtgg cagaagatga aggactgaaa gttgatcatg
    27121 ctggttttga aaaagaaatg gatgcacaac gcgaacgtgc tcgctctgcc cgcagtactg
    27181 aaaaatcaat gggggtacaa tctgctttat tgacagatat caaagtagaa agtaaattca
    27241 ttggatacac agaacaagaa tcagatagtc aattattggt catcgttaaa ggtgagtctc
    27301 ttttgaatga agtcgcagaa ggtgaagctc aaatgatctt tgatcaaaca cctttctatg
    27361 cagaaatggg tgggcaagta gcggatcaag gatggatcat gaatgaagta ggcgaaatcg
    27421 tagcagttgt tacagatgtt caaaaagcgc ctaatggtca atttatgcac accgtagaag
    27481 taaaagcacc aatgagtgaa ggacaaacct atcatctatt gatcgatcaa tcgatgcgca
    27541 atcggatcat caaaaaccat acagcaaccc atctactgca caaggcattg aaagaagtac
    27601 ttggcgagca tgcaaatcaa gctggttctt tagtcgctcc tggacattta cgattcgact
    27661 ttacccactt tggtcaaatc acttcagatg aattagctga aatggaaaga atcgtcaacg
    27721 aaaaaatctg ggaagctatc ccagttgaaa caattgaaac agatatcgat acagccaaaa
    27781 acatgggtgc aatggctttg tttggtgaaa aatacggaca tgacgttcga gtagtaaata
    27841 ttggcggctg gtcaatcgaa ctgtgcggag gcacacatgt agcaaataca gaaaacatcg
    27901 gaatcttcaa aatcgtttct gaatcaggaa ttggtgcagg cgtgcgacga atcgaggctg
    27961 taacaagtaa agaagcgtac gaactacttg aagaagaaga aaaacaacta aaacaagtag
    28021 caacaattgt taaatcacct caattgaaag aagttgtttc aaaagcggaa caattgcaac
    28081 agcaagtaag agagctacaa aaggaaaatg aacaattagc tagcaagtta gcgaatcaac
    28141 aagctggtga tgtattcaaa gatccagaaa cgatcaatgg aaaaacaatc attgcagcac
    28201 aagtaaaagt gaaagatatg aatcagctgc gtcaattagc tgaccaatgg aaacaaaaaa
    28261 atatttcaga tattcttgtt ttagcaaacg aacaagaagg aaaagtcagt ctgctagcgg
    28321 caatgacgaa agaatcaaat gaagctggac taaaagctgg cgacttgatt aaagcaatcg
    28381 caccgaaagt aggcggtggc ggtggtggac gtccagacat ggcacaagct ggcgggaaaa
    28441 atcctgctgg tattccagat gcacttaaag ctgcgaaaga atgggttgcg caacaatagg
    28501 gcgtttacgt ttgacagaaa aacaaaagtt caaacattga acgaaacatg attatggggg
    28561 cgaagacaaa caagtcttgc cctcatactt ttttcaattg gatggcgcat ctaatcaaat
    28621 ggtcggattc ggatggtctt tagttgacga aagtgacaga aatttttacg attagtataa
    28681 ataaaaaggg gtgaaaaaat gaatagtaga aataagacct ttcgactagt cttacgtgcg
    28741 atcttgttag caatcatcat cgtacaagcg atggttcctt ggctggggtt tattccatta
    28801 ggattcatta gtttaacaat tatccatatc acagtaatta ttgctgcagt agtattaggc
    28861 ccaaaagatg gcatggtgat tggcttgttt tggggaatcg ctacaattgt tcgtgcctat
    28921 gccatgccaa caacgccatt tgatacatta gtgttcacga atccgattat ctcggtagtt
    28981 cccagagtac ttgttggctt agtagcaggc ttggttttcc actggattta tcaaaaaaat
    29041 aaatcaataa cgatcagctc agcctttgca ggggtactgg gttcattggt caatacagtc
    29101 ttagtgttag gattcatggg attattttat acaggtgcaa cggcagatgc ctatggtgta
    29161 gactctgctc ttttatttaa aaccttagca ggggttgcag caatcaatgg gataccagaa
    29221 gcaataggtg cgggaatcat aacaccatta ctagcaaaag cgttatttgc agcaacaccg
    29281 ttgaaaccag aataatgacc atcttttaat agtaatagga cgcacgatag atagaaaaag
    29341 gaagagagga gaggaaaaca atcgtcctct ccatcttttt acctgagcaa caagcaaact
    29401 agaaggggta aaaaacttgg ctaagaaaca agaagaaaaa aagaaacaaa taccgcaaca
    29461 gcggacaaaa aaaggagtac tagcgggtat cttaggattg gttacgaatc tgatcttgtt
    29521 tgtctctaag ctaatgatcg ggcttttttc aggaagtgtc tccattatgg ctgatgcagt
    29581 gaacagtcta tcagatactg cttcatccat attgactttg atcggattta aaattgctgc
    29641 aaagccagca gatcaggaac atccttatgg acacgaacgc ttcgaatata tcagtgggtt
    29701 atttgtttcg atcatcatta cttatgtagg atttcaattt ttagagtctt ctgctgaaaa
    29761 aatcatccat ccagaaaatg tctctttaac acccatcgtc ttttttgtcc taatcatttc
    29821 catctttttg aaatttgcac aaggcaaaat gtatcaggtt attgcgcaat ccattgattc
    29881 tgaaacattg agagctacag caacagatag ttataatgat gtctttacta cactggctgt
    29941 attgctttca gcagcaatcg aatgggtaac tggatggcgt attgatggat atataggttt
    30001 tgctttagca ttatatatcc tttatagtgg attgacgatg cttcgaaatt ttgtatacga
    30061 actattagga agtcgcccaa cgccagcaga gattgaagaa atggaagagc atttaaatgc
    30121 ttgcgatgat atacttggct atcatgattt attggtgcat aactatggac ccaataaacg
    30181 ctttgcatca gtccacatcg aagtagatga atcaatgaat ttgaatgtgg ctcataagat
    30241 tattgatctg atagaaaaag actttaaaaa gtctttggat gtggaacttg tctgtcactt
    30301 ggatccaatg cctgttgata acgaaaaata ctataatatc ttgcggcagt taaagcaaat
    30361 tcttcttgaa acaggtacag ggcttaatat tcatgatttt agagtaattc atcaaggaaa
    30421 aacgctgcaa tttgatgtag tggtccctga gaaattccag tttgttgata cagaactaga
    30481 aagaatctta cgtagtcaaa tagaagaaaa aatcggagat taccaattgg aaattacgtt
    30541 tgatcacaat tatcttttat attaaatgag aaactataaa aagactcctt aaagttttta
    30601 atttaaagag tctttttttc ttttaattgt ttatggagag cctgacgtgc aagattatct
    30661 gctcctttat ttttgttttc gggcaaccat tgcaggatca ataaagaaaa ttcggataga
    30721 agttcttgga ttctttgaag gtagggaagg aagagctcgt tcttcgttgc gtttttgtcg
    30781 accgtagaaa ctagtgtttt gctgtctgaa aaacagaaaa tcgtttcatt ctgtaagtcg
    30841 tttttcttta gaaattctaa agtttttaaa aagacttcga actctgcttg atggtttgtc
    30901 cctatagaaa gcgggataga tagctgttct tgtttacctt gatagacaat caagattcca
    30961 cctccactag gaccagggtt gccttttgta gaggcatcaa tgtatacttt taacataaaa
    31021 agagattctc ctttttgttc aaactaatgt tatggtaaga ttatatcatt actgaatcgg
    31081 tgagaggtta gagaatgaaa aaaaatattc gatggcagcc tgaactggca catacgatca
    31141 tctattggtc attgaccttg atcattctgt tttttagtct gattctttct ttagaaaaca
    31201 caggtcctta ttggaaaagc aattttgttt taggtatttt tcttgttttt ctatttctag
    31261 gtttgcggcg ttcttttatt ttaaaatcaa actctgtgat tatacgttat gctgcttttt
    31321 ggaaagaccg agaaatatct gtcggacaga ttcgatcttt gacgccaact aatactgggg
    31381 tgcaaatgat gttgcaagat gagaaagccc catctgtttt catgatgcga aaaaaagatc
    31441 aagtagtcct ttttgatcat tttgaaaaaa acggacccaa atcagaatca attccttatc
    31501 cttatacgaa aaaaagaaaa agctaatttt aaaaatcaga acctaaaaaa acgaattttt
    31561 acaggaaaag aaaagagtga gacgtacggt tcatcccgtt tagcgtctca ctctatttgt
    31621 ttatctattc atgcatacta gtatcggtag tctgaacgtt gcctttcttg acatgggcag
    31681 cttgtgttcc tcgattccct tcgatgatct caaattcgac cacttgattt tcttccaaag
    31741 ttttgaatcc ctcttcttca atcgcagtaa aatgtacaaa aatttcttct gtgtcatcat
    31801 aactgataaa gccgtatcct tttttgttgt caaaccattt tacaattcct gtggtcaaag
    31861 cactcacgac ctttctaaag tctgatcata gccttcatta taaagagtat ttataagtac
    31921 gtcaaataaa ttaaaaacct gtaattttat gttttttttc tgaataaaaa aaggtataat
    31981 tggcatatct taacaaagaa gatattttgt tgaataaagt tcgtgaaaag gggtaatcaa
    32041 atgaagaatg atctgcaaat ttcacaagaa acagagctag aaccgattgt tgaagtggct
    32101 agtaaattag atcttaagga agacgatttg gaactgtatg ggaaatataa ggcgaaaatc
    32161 aatttttctg gaatcaatcg atcaaaggat aacgctgagg ggcatttgat cttagttact
    32221 tccatcaatc caacaccagc tggcgaagga aagtcaacga tcactgtagg gttaggagac
    32281 gcgctcaata aaatcaataa aaaatctgtt attgcattgc gagaaccctc acttggtcct
    32341 gtgatgggaa tcaaaggtgg tgctgcaggc ggaggatatg cacaggtatt gcctatggaa
    32401 gatatcaact tgcattttac tggtgacatg catgctatca caacagctaa taatgcatta
    32461 tctgctcttt tagataatca tattcatcaa ggaaatgaat tgaacatcga tgcccgccga
    32521 gtgatttgga aacgggtagt cgatctcaat gatcgtgaac tgcgtaaagt aattgttggc
    32581 ttgggtgggc caatccaagg tgttccaaga gaagatgggt ttgatatcac agttgccagc
    32641 gaaatcatgg ctatcttgtg tcttgcggca gaccttgaag atttaaaggc tcgtcttgca
    32701 aggatcgttg tcggctatac atttgaccgt cagcctgtga ctgctggaga cttgaaagca
    32761 gaaggcgctc tggcattact gctgaaagat gcaatcaagc cgaatcttgt acaaacaatt
    32821 tacggaacac cagcttttgt ccacggggga ccgtttgcca atatcgctca tggctgcaat
    32881 agtattttag ctaccaagac agcattgaga ttagcagatt acgttgtcac agaggcagga
    32941 tttggtgcag atcttggcgg agagaaattt ttagatatca aagtacctaa cttgaaaaaa
    33001 gcgccggatg ctgtggtgat tgtcgccact gtccgtgcat tgaaaatgca tggcggaatg
    33061 aaaaaagatg aacttaaaaa tgagaatctt gatgctttga aagtaggttt tgcaaattta
    33121 aagcgccata tacgtaatat ggaacaatat cagctacctg tgatcgtcgc aatcaatgaa
    33181 ttcgtaacag atacagacaa tgaactcaca ctgttggagc acttgtgtga aaatcagggg
    33241 attcttgcca agagagcgag tgtatgggca gatggagcag aaggcggcgt tgatttagca
    33301 aaagctgtag tacgattgat tgatagaaaa gaagctaatt acaagccatt ataccgccta
    33361 gaagaaacga tacaagaaaa gacagaaaca atcgtcaaga aaatttacgg aggaaatggt
    33421 gttgttttca gcaaaaaagc gcaaaaacaa atagaagagt ttacgaagaa tggatgggac
    33481 aaactgccga tttgtatggc aaaaacacag tattcatttt ctgatgatcc ttcactgcta
    33541 ggtgcaccgg aagatttcac catcacgatc cgcgaaatca tcccaaaatt aggggcagga
    33601 tttttagtag ccttgactgg agatgttatg acgatgcctg gtttgcctaa aaaacctgct
    33661 gcattgaata tggacgtgac aaatgacgga gaagtgttgg gattgtttta agcttgatta
    33721 taatctacca tcgaaggagc tgtattttga ctacagcttc tttttttaga cgatagggaa
    33781 ttaattttgt ttacactagg atcattcttt ttctttattg tattttgagc tatactaaag
    33841 cataatagga gggtatgatg aaaacgacat ttataagaaa aaccggtttt tacggtatgg
    33901 gtagctcgat tcagctaaga atcaacaatg aaaaacgcag tgttctcagt catgaacaaa
    33961 agataacgct tgatctggaa gtgcccttta cgatgcaggt caccttttat tggctaaaaa
    34021 gccccgttta tacagtgaaa gaagcaaagc ctgcttatgt gatcacaatg aattacttga
    34081 ttcttcaaat ctatccgttt ttatttctag caactgggtt gggggccgtt ttcctacaaa
    34141 atttattttt cagttttttt gcagttattg tgttgattgc gttctttttc tatataaaaa
    34201 accgggcata tttgatcaag gaggaaaatt atggcaaact ctgatctttt tttaatcagt
    34261 ttcaatcgaa tcgaaaaatg gatgagagac gagatgggaa atgcacgaaa tatgggattt
    34321 accgaacttg tcagacgcct agctcaaaga aaacaattaa tgatcagaaa atacgaagat
    34381 gatcttttac agcttgctca gttaaggaat gcgatcgtcc atgatcggat cgcagtcgat
    34441 tttgtcattg cagagccaaa tgattggaca gtcaagcgaa tccagctgat cgaacaagaa
    34501 ctgattcagc ctgaaaccgt gctgcctcga tttgcaaaac gtgtaacagg ttttgaacaa
    34561 gatcttccgt tacttgaact gttaaagata gtagcagaaa aaaggtattc acaatttccg
    34621 ttatacaata aaggaaaatt tgtagcattg attactttac gtaatatcgg gttttggcta
    34681 gcaaaagaaa gccaaaaagg tccggttgat ttaacaaata aacgagcgtt ggatttgatc
    34741 atccaaaacg gaaagtacac aaattatcat tttgttccag ctaaaacaca tatttacgag
    34801 gttgaagcga tgtttcgtga gcaagggact ttggaagccg tacttatcac taaagatggg
    34861 aatcccgatg gtaatctgct cgggatcgta cgacctcgtg atatttataa acaaatagaa
    34921 aaggattgat tttttgttaa ttatttattg gatattcagc gctttgctag taggagtgga
    34981 tcagttggtc aaatggtgga tcactgataa tctagcgctt ggagagacga aaaatcttat
    35041 accaggtatt ttgtcactga atcatattcg aaacactgga gccgcatgga gtatgctaga
    35101 agggaagatg tggttcttta ctatagtgac actcattgca gtcgttgtga ttctcacatt
    35161 gatgattaaa aatcgtgaaa aaggtaatcg ctggttcatg attggattga gtttgattct
    35221 agctggtgcg attggcaatt ttatcgaccg tattcgtctt ggctatgtag tagatatgtt
    35281 ccagacagat tttatgagct ttccgatttt taacgtagca gatgtgacac ttgtatgtgg
    35341 agtgatttgt atgttaattt atattatttt agatgaaaag gatcaaagaa aaaaatgaca
    35401 gaacttaaaa cgacgattca ccatgaatct ggtaggatcg ataaagtatt gactaattta
    35461 ttcaccgatt acagtcgttc gcaaattcag ctgtggctga aaaatggagc ggtttctgtc
    35521 aatggacagc cagtcaaagc aaattacaaa gtaaaacaag gagacgagat tactgtcttg
    35581 atccccgaac cagaaacatt agatgtggtc ccagaaaata tcccgttgac gatcgtttac
    35641 gaagatgaag atgtagcggt gataaacaaa cctcaaggaa tggtcgttca tccttcagca
    35701 ggtcatacgc atggcacaat ggtcaatgcg ctgatgtacc atatcaagga tctttctacg
    35761 atcaacggcg ttattcgtcc aggtattgtt caccgaatcg acaaagatac ttccggactg
    35821 ctaatggttg ccaaaaatga ccaggcacac gaatcattag ctcagcaatt aaaagataag
    35881 acctctttgc gcaaatatgt tgctttagtc catggagaga ttcctcacga aaaaggaacc
    35941 atcaatgcgc caatcggccg ttcgaaggaa aaccggaaaa tgcaggcgat aagagaagat
    36001 gggaagtcgg ctgtcacaca ttttactgta ttggaacgtt tcgaaggatt tactctggtt
    36061 gaattaaaac tagaaaccgg aagaacacac cagatccgtg tgcatatgaa gtatatcggt
    36121 tatccgttag ctggagatcc agtatacgga ccgaagaaaa ctttgaaagg caatggtcag
    36181 tttctccatg cgcaaatgtt aggttttacg cacccgacta caaacgaaaa gatgatcttt
    36241 gaagcacctc ttccagaagt ttttgaaaaa actttagaaa aattaagaaa aaacattgca
    36301 ttttaattta gataacggta tagtaattaa caacgaaagc ataaaactta atagaattcc
    36361 tttaagttta gtcccgtgag gctaagaagg gtgggagcaa ggatacgtat ggtgcgccat
    36421 aagtagattg ctcattgaca tagtatagct atcagtgtat cagtatacgc tcagtctaaa
    36481 cattcctcct gtcctcttag ggcaggagtt tttttatgca aaaaagtagg gggaatgaaa
    36541 atgcaagcaa aagaagtagt agatcaggta accatgaagc gagcattgac tcgaattact
    36601 tatgagatta tcgagagaaa ccatagtatc caagatatcg tattggtagg tatcaaaaca
    36661 cgaggaatct acattgcatc aagaattgcc gaacgcctga agcagctaga agatatcgat
    36721 attcctgtag gagaactgga tatcacttta taccgagatg acaaaaaaga aaatccagaa
    36781 gaaccggaac ttcattcttc tgacatccca gtttccttag aaggaaaaga agttattttg
    36841 attgatgatg ttttgtatac aggacgaacg attcgagcag caatggacgc agtaatggat
    36901 tttggcagac caagaaaaat ttcattagca gtcctggtcg atcgtgggca tcgagaattg
    36961 ccaatccgtg cagattatgt tgggaagaac attccaacat ctcgggcgga agagatttta
    37021 gtagagatgc aagagcttga tggacaagat cgcatcatga ttttgaaaga ggaagattag
    37081 aggagagaga aacatgtcgg agaaaaaagg atttcataat gatgacgtgg tgttagatat
    37141 ccacgatcgc ccaaccccag gacattgggt aggattaagt ttacaacact tgttcacgat
    37201 gttcggagca accgtgttag tccccatctt agtaggtatc gatccaggta ttgcgctagt
    37261 cagttcagga ctaggtacat tggtgtactt atttactact aaaggaaaga tacctgcgta
    37321 cttaggaagc agcttcgctt tcattgcagc gatgcagctt ttgatgaaaa cagatggtta
    37381 tccagcgatt gcacaaggag cagtcacaac tggattagtc tatttgattg ttgcgctgat
    37441 catcaaaaag atcggttcag catggctgga taaaatcttg cctccaatcg tcgtcggtcc
    37501 agtcatcatg gttatcgggt tgggacttgc ggcaaatgca gcaacaaatg ctatgtataa
    37561 tcagggcacg tatgatttca agtatattgc tgtagcgctg atcacattag gattaacaat
    37621 tttcttcaac atgtggctaa gaggttttct cggattgatt ccgattttac taggtattat
    37681 tagcggatac atcgtagcct tgctgtttgg aatcgtggat actaagccaa tcgtagacgc
    37741 tgcctggttt gctgttccta actttgagat tccctttgta caatatgaac caaagctata
    37801 tcttggagca atcacaacaa tggcacccat cgcttttgtg acgatgacag agcatatcgg
    37861 ccatcttatg gtattgaata aactaactaa acgtaatttc tttgaagaac cgggtcttca
    37921 taagacgttg acaggtgatg gattagcaca aatcgtggca gcctttgtcg gaggtcctcc
    37981 tgtaacaagt tacggtgaaa acattggtgt tctggctatc acacgtgtcc atagcgtgtt
    38041 tgtgatcggt ggagctgcag tatttgcagt cattttagga ttcgtaggaa aattaagcgc
    38101 tttgatttta agtatccctg gaccagtcat ctcaggaatc agttttatct tatttggagt
    38161 aattgccgca agtggaatga agattttaat cgagaacaaa atcgattttg ataaaaagaa
    38221 aaatctgttg attgcttcag ttatcttagt agtaggaatt ggcggactcg tctttgaagt
    38281 aggcacattt acattgtcgg caatggcatt agcaactgta cttggcatca ttttaaatct
    38341 tatcttacca gaaacttcac gaagcgaaga aaactaagga ggaaacatta tgatcatcaa
    38401 atcagaacgt atcagcttaa agcatttatt gaccgttgag gcacttactg atcaagaagt
    38461 tatgggcttg atccgcagag ggcaggaatt caagcaaggt gctaattgga ctccgcaaaa
    38521 gcgccagtac tttgctacaa acctcttttt cgaaaatagt actcgcacac ataaaagctt
    38581 cgatgtagcg gagaaaaaac tagggctaga agtgattgaa tttgaagcaa gcacaagctc
    38641 tgtccaaaaa ggggaaacac tatacgatac agtactgacg atgtcagcat taggcgtaga
    38701 cgtagcggtt atccgtcatg gtgatgagaa ctattatgac gaactgatac aaagtaaaac
    38761 aatccagtgt tcgattatca atggaggaga cggaagcgga cagcatccaa cccaatgctt
    38821 gcttgatttg atgaccattt atgaagaatt tggtcatttt gaaggtctga aagttgccat
    38881 cgtaggtgat atcactcact ctcgcgtagc taaatccaat atgcagatgt taaaacgtct
    38941 aggcgcacaa gtattcttct caggtcctag agaatggtac gacgatgaat tcgaagtgta
    39001 cggacattat atgccattgg atgaactact agatcaagtt gatgtcatga tgatgcttcg
    39061 ggtgcaacac gaacgccatg atggaaaaga aagtttctca aaagaaggct accatcagga
    39121 acatgggtta acagttgagc gtgcgaagaa gttgcaaaaa catgcaatca ttatgcaccc
    39181 agcaccagtt aaccgtgatg tagaattagc tgattcatta gtggaaggat tacagtcgcg
    39241 gatcgttcag caaatgagca atggagtatt cgtcagaatg gcaatcttag aagcagtgct
    39301 aaatggaaaa gcgtaattat aggaggatga aaaaatgaaa acactcatta aaaacggtca
    39361 gatcaataca cgaaaaaata tgacgacacc agcagaaatt tggatagaag atgggcgaat
    39421 caaagcaatc ggtacaggat tctcagaagc cgaatttgat gaagtgtttg atgcaaaggg
    39481 acaattgatc acacctggtt tagtggacgt ccatgttcat ttgagagagc caggatttac
    39541 atacaaggag acgatcgaag ctgggactcg ctcagctgct cgtggcggtt tcactactgt
    39601 atgcgcgatg ccgaatttaa atcctgtacc tgatacggca gaaaagctga gacaagtata
    39661 tgacatcatt agaaaagatg cagttgtgaa ggtattgcag tatgcgccaa tcacagaaaa
    39721 tctgcgaagt gagaaattag ttgatcaaga agcactgatt gaagaaggtg cttttgcttt
    39781 cacaaatgac ggtgtaggtg tccaaacagc tgggacgatg tatctggcta tgaaagaagc
    39841 tgcaaaaaac aataaagccc tagtagccca tacagaagat gaatctttat tatttggcgg
    39901 cgttatgcac gctggcaaga aggcagaaga acttggtctt cccgggatct taagcgtaac
    39961 cgagtcttct caaattgcta gagatctgtt gctagctgaa gcaactggtg ttcattacca
    40021 tgtttgccat gtttctacta aagaaagtgt ccgtgtaatc agagacgcaa aaaaagcagg
    40081 aatccacgta acagcagaag tttcacccca tcatcttatt ttgatcgacg aagatattcc
    40141 cgaagatttc ggcttttgga aaatgaaccc gccgctaaga ggacgggagg acagagaagc
    40201 tttgatcgaa ggcttgcttg acggtacgat cgattgcatc gctacagacc atgcccccca
    40261 tggattagaa gaaaaaagcc aaagtttcat gaaatcacca tttggtatcg taggaagcga
    40321 aacagcgttt caactgatct atactcattt tgtagaaact ggtcgattca cgttggaaca
    40381 agtgatcaat tggttggcag ttaaaccggc tgagattttt ggtttgaatg caggaacgct
    40441 aacggttggt gcccccgctg atgtagcagt ttttgatatt acacaaactt gcacgatcga
    40501 taaagaagac tttttatcaa aaggggagaa tacacctttt atcggctgga aagtaaaagg
    40561 cgaaacacaa atgacttttg tcaacggaaa acttgtgtgg cagaagggag aataaaagta
    40621 tggaacgttt gcttatatta gaagatggaa cagttttcga aggaaaggct tttggtgcag
    40681 atgctagtgt cttcggagaa atcgttttta caacaagtat gactggttat caagaaacta
    40741 tcactgatca aagttttaac ggtcaaatca ttacatttac ctatcctatg gtgggtaatt
    40801 atggggtaaa tagagatgat tatgaatcga tttctccaac atgcaaagga gtagtagtaa
    40861 aagaacatgc acgtgtagct tcaaactggc gaaaccaaat gacgctagat tcatttttga
    40921 aacaaaaagg aattcctgga atatcaggta tcgatacgcg cgcccttact cgcaaaatcc
    40981 gtgaagtcgg aacgatgaaa gctagtatag ttgatgctgg agattccttc gaacatgcat
    41041 ttgatcagct gaaagcaacc gttctagcaa ccaatcaagt gcagcaagtc tcaactaaca
    41101 aaccttatcc aagtccagga acaggtcgga aagtcattgt cattgacttc ggcttgaaac
    41161 atagtatttt acgagaattg agtaaaagaa actgtaacct cacagtactt ccctataaca
    41221 cagatgccga gacgatttta gcgctatcac cagacggagt catgctgacg aatggacctg
    41281 gtgatccaaa agatgtgcca gaagcaatcg aaatgatcaa aaaaatccaa ggaaaagtac
    41341 cgatttttgg tatttgtctc ggtcaccagt tatttgcttt agccaacggt gcagatacct
    41401 ataaaatgaa attcggacat cgaggattaa atcacccggt acgagaagta gcgaccggaa
    41461 gaattgattt tacttctcaa aatcatggct atgcagtcga tgaagccacg attgatccag
    41521 aaaaactcat cgtaactcat gtagaagtaa atgacggaac agtagaagga gtcaaacaca
    41581 gagattatcc cgctttcagt gtgcagtttc atccagatgc tgcccctggt ccgcatgatg
    41641 cactacattt atttgatgaa tttatggaaa tgatggacgc aggaaaggag cagtaaacag
    41701 atgccgaaac gtacagatat caagaaaatt atggtgattg gatctggtcc gatcatcatt
    41761 ggtcaagccg cagaatttga ctacgcagga acacaagcct gccttgcctt aaaagaagaa
    41821 ggatatgaag tggttttagt aaattctaat cctgcgacga tcatgacgga taaagaagtg
    41881 gcagatcaag tatatatcga accgatcaca cttgaatttg tatcaaggat tcttcgaaaa
    41941 gagcgtccag atgctctcct tccaacttta ggcggacaga caggcctcaa tatggcaatg
    42001 gagctggcag catcaggtat tttagaagaa ttgaacatag aacttctagg aacaaagctt
    42061 tctgcgatcg atcaagcaga agatcgtgat ctattcaaac agttgatgaa agaattgaat
    42121 cagccaatcc ccgagtctga aatcgtcaat acagtagaag aagctgtaga ttttgcaaat
    42181 aaaatcggct atcctgtcat cgttcgtcca gcctttactt taggcggaac tggtggaggt
    42241 atgtgtgaaa atgaagaaga attacgtatc gtatcagaaa atggattaag tctttccccc
    42301 gctacccaat gtttgattga acgaagtatt gcaggtttta aagaaattga atatgaagtg
    42361 atgagagatt cggctgataa tgcaatcgtt gtctgcaata tggaaaattt tgacccggtg
    42421 ggtatccata caggtgattc tatcgtattt gcccctagtc aaacattgtc tgaccatgaa
    42481 tatcaaatgc ttcgtgatgc ttctctttcg attattcgag cacttaagat cgagggaggc
    42541 tgtaatgtcc aactcgctct tgatccacat agttttaatt attatgtgat tgaagtcaat
    42601 ccgcgtgttt ctcgttcatc tgcgttagca agtaaggcga ctggctatcc gatcgctaag
    42661 ctagctgcta aaatagcgct tggattaaca ttagacgaaa tgaaaaatcc tgttacagga
    42721 acgacttttg cagaatttga acctgcatta gattatgttg tagctaaaat tcctcgctgg
    42781 ccgtttgata agtttgaaaa cggagaacgg cttttaggca cgcagatgaa agcaactggt
    42841 gaagtgatgg ctatcggtcg gaatatcgaa gagtctttat tgaaagctgt gcgttcttta
    42901 gaaatcggta cacaccatat cgaacttcct gagttggcag acatcacgga cgatgaccta
    42961 atccaaaaag tggttcgagc acaagatgat cgcctgtttt atgtagctga agctattaga
    43021 agagggtaca ccatagaaga attagcggat ttgacaaaaa tcgatttatt ctttttagat
    43081 aaactgttgc atatcgtaga aatcgaacag cagttgaaac agcagccgtt ggatgacaag
    43141 atattgaaaa cagcgaaaca aaacggtttt acagacaaaa aagtggcgga gctgtgggaa
    43201 ataaacgaag aagccgttcg ccagatgaga aaagaaaatg atttgattcc tgtatataag
    43261 atggttgaca cttgtgcagc ggaattcgaa tcaaaaacac cttattttta tagttcctat
    43321 gaatatgaaa atgaaagttc acgatcagaa aagccctcaa ttctagtact gggatctggt
    43381 cctatccgta tcggacaagg ggttgaattt gactatgcga ctgtgcattc tgtcaaagca
    43441 atccagcagg caggatacga agcaatcatc atgaacagca atcctgaaac agtttcgact
    43501 gacttttcta tttcggataa attatatttt gagccattga ccttcgaaga tgtgatgaat
    43561 gtgatcgagc tagaacagcc gataggagta atcgttcaat ttggtggtca gacagcaatc
    43621 aacttagccg aacctttgac tgctgctggt gtaaaaatct tagggacaac gatcgaagac
    43681 ttggatcgtg cggaaaatcg tgatttattc gagcaagcgc tgaaagagtt ggatattcct
    43741 caacctttag gggatactgc tacaagtaaa gaagaagccg tggttatcgc ttcgagaatt
    43801 ggttatccag ttcttgttcg tccaagctat gtattaggcg gacgtgcgat ggaaatcgtt
    43861 gaaaaccagc gagatttaga agattacatg gaacatgctg tgaaagcatc tccagaacat
    43921 ccagtactag tggaccgtta cttgcttggt ggtgaatgcg aagtggatgc gatttgtgac
    43981 ggtgaaacag tactcatccc agggatcatg gagcatattg agcgtgctgg tgtccattca
    44041 ggggattcaa tggctgtgta tccacctcaa acattatctg aatcgatcaa gaaaacgatc
    44101 gaagattaca cgatccgctt agcattaggt ttgaattgtg tcgggatgat gaatatccag
    44161 tttgtcatcc atgaaaatga ggtttatgtg atcgaagtca atcctcgagc aagtcggact
    44221 gttccattct taagtaaggt gacaggaatt ccaatggcac aaattgcgac gaaagctatt
    44281 ttgggagaga aactaaagac acttggttat gaaaacggac tttatccaga aacaaaagaa
    44341 gttcatgtta aagcacctgt cttttctttt acgaaattgc agaaagttga tacttactta
    44401 gggcctgaaa tgaaatcgac tggagaagta atgggatctg acagacaatt agacaaagct
    44461 ttgtacaagg cattcgaagc ttctggatta cacttgcctg aatatggagc cgtattattt
    44521 acgattgcgg acgaaacaaa agaagaagca ctagaattag ctaaacgttt tacagaaatt
    44581 ggctatagtc tgataggaac gaaacataca gctgcttatt tcgaaaaaaa tggtctggtc
    44641 gttgaaacag tagcgaaaat ttctgaggaa gcagcagaaa aaaatgtagt cgacttaata
    44701 agagatggta aaacacaagt ggttgtcaat acgattgata aagatcgggg aaatgcttct
    44761 aaagacggtt tcatcatccg aagagaagca gttgaacatg gtattccatt gtttacttct
    44821 ttagacacag cagatgcgat cgttcgagtg atggaatccc gtgctttttc aactaaccct
    44881 atttaacggc gagcacatgt taagacaaaa agacgaaaaa ccgttgcagg aggggacaga
    44941 tgaaacaaga aatgatggaa atcgttcagc aaaaacagct ggcaccaaag atttttgaaa
    45001 tgacattgaa aggtgatcta gtaaaagaaa tgcagcaacc aggacagttc ttgcatattc
    45061 tcgtgccgcg tgcagacttg ctattacgcc gaccgattag cttgaatcat atcgaccacg
    45121 aaacaaatac ttgccgtatc atttatcggg tggaaggtga ggggactaga gtcttctcta
    45181 ctctttctgc cggagaccat ttagatgtca tgggtccttt aggcaatggt tttgatttgt
    45241 ccaatcttca tacaggagac gaagtattta taatcggtgg aggaatcggt gtccctcctc
    45301 tatatgagtt atcaaaacag ttagtcgaaa aaggaattaa gccaacgcat tttttaggtt
    45361 ttgccacaca tgaagtcgtt tattatgaaa aagaatttaa tcgtctagga gaaacaagaa
    45421 tcgctactga cgatggaaca tacggtatgc acggaaatgt cggtaattta ttgttaggaa
    45481 cgaagacgga acctacagct gtttttgcat gtggttcaaa cgggttattg aagacagtgg
    45541 aacagctgtt ttcttcgcat caaaatgtcc agttatcatt agaatcccgc atggcatgtg
    45601 ggataggggc ttgctatgct tgcgtttgtc atacgccgga agatgaaaca ggaacaaaaa
    45661 gtgtgaaagt ttgtgacgaa ggaccgattt ttaaaatagg agaggtaatt atatgaatga
    45721 gaatccttta gcggtcaaac ttcctggcct agaattaaaa aatcctatca tgccggcaag
    45781 cggctgtttc ggttttggca aagaatacgg aaaatactat gatttgaatc agcttggatc
    45841 gatcatggtc aaggcaacga ctccaaatgc ccgctttggc aatcccacgc caagagtggc
    45901 ggaaacacca tctggcatgt tgaatgcaat tggtttgcaa aatcctggtc tagacgttgt
    45961 tatgcataaa cttcttccag aattagagga gtacaatgag ttacccatca tcgcaaatgt
    46021 tgctggtgct tgtgaagaag actatgtaga agtttgtagc aaaattggcg aagcaccaaa
    46081 tgtgaaagca atcgagctga acatttcttg cccaaatgtc aaacatggcg gaattgcttt
    46141 tggaacagat tctgatgttg cttttcaatt aacacaagca gtaaagaaag tttcttctgt
    46201 tcctgtctat gtcaaattgt ccccaaatgt aacagacatc gttccaatcg ctcaggcaat
    46261 cgaagctgga ggggcagatg ggtttacgat gatcaatact cttcttggta tgcggattga
    46321 ccttaagaca agaaaaccga ttttagccaa tcaaacaggt ggactctccg gaccagcaat
    46381 caagcctgtc gctattcgtt tgattcacca agtagcaagt atatccagcc ttccaatcat
    46441 tgggatgggc ggcgtgcaga cagtggatga tgttcttgag atgtttatgg ctggagcaag
    46501 tgctgtagct atagggaccg cgaatttcac cgatccgtat atctgtccta aactaattaa
    46561 agagctccct gtgcgaatga gcgaactagg catcgaatcg ctggaaagat taatcaaaga
    46621 agtgagagag gaacgtgaac gatgaatcaa ctagaccaac gaccaattat tgcattagat
    46681 ttttcaacta ggcaagaggt agaagacttt cttcgatttt tcccgaaaga agaaaaattg
    46741 tttgtgaaaa tcggaatgga attgttctac caagaaggac ctgaaatcgt acgttatcta
    46801 aaagaggctg gtcataatgt atttttagat ctgaaacttc acgatattcc gaatacggtc
    46861 gaaaaagcaa tgcggggatt ggcaaagctt ggtgttgatc tcacctgtgt tcatgccgct
    46921 ggcggtattc gtatgatgga ggcggcaatg cgaggattag aagaggggac tccagaaggt
    46981 ggaaaacgtc cgctacttct agctatcact cagcttactt ctacaagtga agaagaaatg
    47041 catgccgatc aactaatcga agtttcttta gaaaaaagtg tgatccatta tgctagctgt
    47101 gccaaaaaag caggattaga tggtgtggtt tcttctgctt gggaagtaga agcgatcaaa
    47161 gaaatggcag gagacgaatt tgtttgctta actccgggta taagaccaga aggaacagtc
    47221 gcaggagatc agacaagagt agtcacacct tctcaggcaa aaaagatcgg ctcaactttt
    47281 atcgttatag gtcgaccaat cactcagtca actaatcctt ataaagcata tcaaacgatt
    47341 caaacagaat ggagctaacc taaaatgaat gttgaacaaa gtatcgcaaa agacttatta
    47401 gaaattgaag cagtattttt aaatccaagt aatcctttta catgggcaag tggaatcaaa
    47461 agcccaattt actgtgataa ccgaatcacg atgagctatc caaaagtccg aaaagagatc
    47521 gcaaaaggat tagcaagcaa aatcaaagaa gcttaccctg aagtacaagt gattgctgga
    47581 actgcaacag caggaatccc tcatgccgca tgggtagcgg aaatactgga tttgccaatg
    47641 gtctatattc gaagtaaggc gaaagatcat gggaaaggta accaaatcga aggacgtata
    47701 tttgaaggtc agaagatggt tgtgatcgag gatttgattt ctacaggcgg aagtgtcttg
    47761 gaagcagctg aagcagcaaa aagagaaggt gcggatatcc ttggtgttgc ggctatcttt
    47821 acgtatgagt tgccaaaagg aaaagcaaat ttcgaaaaag ccgaaatccc tcttatgacg
    47881 ttgaccaatt attctgtatt gattgaagca gctttagaag atcgttatat cgatgagcaa
    47941 gaattaactc tgctaaaaga atggaaaaaa gatcctgaaa attggcagat ttaagcgcgc
    48001 ttgatgaaga tagagaaatc cgatttgtgt ctccagaatc atcaattgga atagcaaaaa
    48061 tccaaaaact gattgcgaga agcatctttt catcaggtat gaaaagaaac ttctatcgtg
    48121 atcagttttt gattttttta aaattcattt ttctaagact ggttagcaga aagaagagaa
    48181 taatctcttc tcttttttct attatatata gattttctct attttttggt aagggagctg
    48241 tttcaaaaat ggtaaagagc ggaaatgttg cgaatatcag ttatttaatg atatgatatt
    48301 cgtaaaaaga aatctcaaag ggaggtaact tttatggggt tgaatgaatt tattttagga
    48361 ttgaacaatt tagagacgat cacaagggca cctggatttt ttaaatatac agagcataca
    48421 gttgcagcac attcgtatcg tgtagcatct attgcgcaag ttctaggaga cattgaagaa
    48481 gcgaatggac aaccgatcga ttggaaactg ctctatgaaa aatcattgaa tcatgactac
    48541 acagagcgtt ttattggtga tatcaaaacg ccggtgaaat acgcaagcaa agagttaaga
    48601 gggatgctgc aaacagttga agaaaagatg acggacgaat tcatcaacca agagattcca
    48661 gctgagttcc aagaagttta tcgccgtcgg ttgttcgaag gaaaagatga aaccgtagaa
    48721 ggagaactat tagccatttc agataaggtt gaccttcttt atgaatcttt tgatgaaatc
    48781 atcaaaaata acccggaaaa agtttataag gagatgttca ttgaggcagt gactacgatt
    48841 aaaagctttg aacatcggcc ttctgttcag tatttcttta aagagatatt tccggaacta
    48901 ttgaaccagg aattttatgg aaaagaggcg tttttagaaa ccgtctcaac gattgtaaag
    48961 aaagaagaaa aataaaaatg atatgagatg cagggggaag tatagttgaa aaagaatatg
    49021 gatgtcgaat ggggctattc tggagacaaa ggtccggaaa attgggcgag tttatgtgat
    49081 tggtttgcga gaggtgcgga atttccattg cagtcgccta ttcatttgac caagggggaa
    49141 gaaaccaaaa tagaaggaga cacgctttcc tttcattatc aaaagcaacg gtttactgac
    49201 aaggaattca aaaacacgat tcatttagta ccttttgacc aactcagtta tgtagagttc
    49261 aagaaagaac gctattattt gacagatatt catttccact tgccttctga acatatcatc
    49321 aacggaaaac aggaagatat tgaatttcat tttgttcata tgaacagcaa aaaagagaat
    49381 ctagttgtgg gtgtcatgta ccagctaatg gtacaggaag gttggctgta taatcaagaa
    49441 aatggggaaa gttggaactt agaaaaacat gagcattggg taaatccgga tgtgttcttt
    49501 ccggagcaaa aaagccattt ccattatatt ggctcattga caactccgcc taccagcggg
    49561 ccaatccaat ggtttgtaat ggatcatgta ggaaaactga accaagagtt tcttctcccc
    49621 ttcgatggtc agtatgctcg accgaacaac cgaccaatcc agcccttgaa tggaagagaa
    49681 atttattatt tcgaggagtt tgagcaatga atattcagca gatgaaatac gtggtcgctg
    49741 tagcaaacaa tggtagtttc agagaagcgg caaagaaaat gtttgtctcc cagccaagtc
    49801 tttcagctgg tatcaaagaa ttagaaaccg agttagggat cacgctgttt actcgaacga
    49861 atcgaggggc atatttaaca gaagaagggc aagacttctt aaatcgtgcc gagaaaatat
    49921 tggtccagct tgatacatta gaaactcact atctaacgag tgaaaagaga gacaattttt
    49981 cgatcgctgc ccagcattat gatttcttag gtcctttgac cgcacagcta ctcgaggaat
    50041 tcaaagacga gatcaaacaa tttcggatca tggagacgac aacagcgaga gtgatcgaag
    50101 aagtcaaaga gcagcacagt gagatcggca ttatttatat gaatgagcat aatcaagctg
    50161 gtatcagaag atatttacaa caaggagagc taagtggccg cagcattgga aaattcaaaa
    50221 cgcatatttt tttaaggcaa ggacatccat tagctgaaca cgcagagatc accaaagaag
    50281 aattgttatc ttatcctcaa gttcgtttta cacaggatgg aaataatttc ccgtattttt
    50341 atgaagacct tatcgagatc cctgatcaag aaacagtgat ttatacgagt gatcgaggta
    50401 ctttgatgaa tatcgttctt gaaactgatg cttacgcttc aggatctggt attgtgattg
    50461 gagggattcg cgagcacttg cggttaatcc ctttggcaga aggcgaacta aatgaatttt
    50521 atatcattta ttcggcgaaa cgtccgctca gtgaaatcgc tcaaagattt atcaaagagc
    50581 ttactcggtt actggaccag cagagctaag aaaagcagat gagaacgctg tttattgaac
    50641 accgttgatc aaaaaagagg ggttgtgaca gaattttgtc acaactcctc tttttgtagc
    50701 aaacaattta taactaattg ctgttgtggg aaagtacgca aatatgattc tagaaacact
    50761 cattgattac ctgttttgtt tcatagctgt aattttttct tcttctggtg tcacgataat
    50821 cgtcttttgg ttttcataaa taacataacc aggcttggcg ccatttggtt ttcggatatg
    50881 ctttacctgt acaagatcaa ccggcacttg ggcagagtat cggtattttg aaaaataggc
    50941 agctaactcg gcagcttctg taattgtttc atctgagggc ttgtcacttt taatgatgac
    51001 gtgcgaaccg ggtatatttt ttgcatgaag ccaatagtcg gtttttttag ctgtcttcat
    51061 tgtcagctgg tcattttgaa gattgttttt accaacaaga atgagcgttc cgtcagaaga
    51121 aaagtattga tcaggctgag atggtttctt acgtttttgt ttttttaagt tcttcttttt
    51181 caggtatcct tctgaagtca attcttcttt aattgcttcg atatccattg ggccggcaat
    51241 ttccagttga gataagacag attcaagata ttggatttca tctttggctt cttggatttg
    51301 ttcgccaatc agcttaacag cgttcttcag cttttggtat cgatggaaat atttctgtgc
    51361 attttgattt ggtgtcaatg ccggatctag tgctattttg attggccgat cttcttcata
    51421 ataattaggt aaaacaactt cttttgcgcc gcgtggtact tgtgtcagaa aagtagtaag
    51481 tagttcgcca tttctacggt aattctcagc gttttcggat tctttgagtg tttgttcacg
    51541 ttttttcaat ttatttttat ttcgttttag ttcattttcg atttttcgaa tcagttctcc
    51601 gccttgttgt tttgcccgat ctttctctgc tttttcgtga taatagctat ctaataattg
    51661 actgagtgtt ggataagctg ttacagcaga tgcctgttcg gacaatacct gataagcaat
    51721 cggtgtgaaa aaatctttat tttccgtttc gtaaaaagta ggaataggct gatggctgat
    51781 ggctgagaaa aattcgtccc atacaaccat cttttcatta ggacgttcca gtaatctttt
    51841 ggtcagctct tgagcgatat cgaaaccgat tccctgaaac tgacgttgga ttgcttttgg
    51901 atctagttca gtttgggaaa gccgctgaaa gattttttct ttctcggagc taaatgggtt
    51961 caagacctct tgttttggcg gagcaacata ttctacacca ggaagcaaag aacgataagt
    52021 gttttgagag cttccaatgt gtttgatcgc atccagtatt tttccagttt ctcgattaac
    52081 taagacgatc gtactatgac gtcccattaa ttcaacgatc aatatgatat tttgtagatc
    52141 acccaactcg tttcgtttag caaagtggaa atggatcact cgatcatttt cgatttgttc
    52201 gatgtcttct aaaatagcgc catccaaata ttttcgaagc atcatcacga agttaggcgg
    52261 attatcagga ttctgataat cgatttgggt aatctgtaca cgagcataac ttgggtgcgc
    52321 agataataat aatcgatggt ttttgccgcg tgaacgaatc accagcacga tttcattttc
    52381 ataaggctga tggattttcg agatccggcc agatagtaac gtttcacgca attcgttgac
    52441 catcgcgtgg gtaaatacac catcaaagga catggttcat tcctcatttc ttttcataag
    52501 tatattcatt ataacgaaaa aaagaagaaa aaccaatttg gccgaatagt aaagcaaaag
    52561 tctagaaaaa tcttggacta attacataaa aaacagtgtt tctatcgttg aaatccaaat
    52621 ttttaggtat aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa
    52681 gtagttaaat cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat
    52741 ccaagtaagt attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt
    52801 gcaatgtttt tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg
    52861 tccataccaa ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa
    52921 caaagccggg cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg
    52981 cttgatgttt ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat
    53041 ccgatcgttt atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg
    53101 acatttattt tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga
    53161 ataactgatt ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc
    53221 aaacaattag aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct
    53281 aattgagaca ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga
    53341 acaagtgatg tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa
    53401 ttcaaaaatt cgatttgact taaatcaatt cttaaggaaa gggtgacctg taatgaactt
    53461 atcaaaacgt atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt
    53521 attaatggtg agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat
    53581 ctatgctaga catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta
    53641 aagacaatga ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata
    53701 ataaataaaa agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag
    53761 ttgtagtaat tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg
    53821 aaaaagaaag tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat
    53881 acgtgagcca tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag
    53941 aaggattaaa agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga
    54001 gcaagctagc cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa
    54061 tcgcaacacc tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag
    54121 gtgctgtaac ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta
    54181 atgtaacagg tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt
    54241 tgttgccaaa tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat
    54301 accaagtagc acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg
    54361 cggtgccttc cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt
    54421 ttatctatgt tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag
    54481 caaacaaagc aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac
    54541 tagcaacaat cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag
    54601 aacttgcgag tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg
    54661 atacagtgat caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga
    54721 aggaaaaagc caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca
    54781 aatgatcgta tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt
    54841 catgacttat cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg
    54901 tgctgctgtc tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt
    54961 aggcgtaggt gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa
    55021 gataccggtt attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt
    55081 tgtgatgcga acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca
    55141 tcgctttggg ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat
    55201 cttgattgct gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac
    55261 aggagacaac gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt
    55321 aggtttaact ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga
    55381 cggatatgca gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat
    55441 catcggtgaa gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt
    55501 cggcagtatc atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac
    55561 ttatctgaag ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa
    55621 gaaagcactg aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg
    55681 acaatcaaaa atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg
    55741 gatgaaatta accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt
    55801 gctggaaaaa gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg
    55861 atctctttta aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt
    55921 tctcgagttt tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat
    55981 ttgctacttg cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat
    56041 caaaaagaag attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg
    56101 gatactccag cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg
    56161 acgatcacag ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa
    56221 acagctaaag cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt
    56281 ctcatgatca cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc
    56341 caaaaaggga aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc
    56401 gaccttttgc agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag
    56461 tagaaggact tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata
    56521 aacaattaaa catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa
    56581 atagaatatt ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc
    56641 tagacgtttc gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac
    56701 aaaggaggaa taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg
    56761 cttctcacag tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg
    56821 cggtgtattt agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc
    56881 gaacttttga tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt
    56941 atctggatga ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg
    57001 aaaagggtcg tttgattggc tataatactg atggtgcggg cttcatgcaa tccgtgcaag
    57061 aagctgggat ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa
    57121 aggcagtcac tgttcaagca gcgttagacg gcgctgagga aatcgtagtt tataaacgaa
    57181 acaaccaaac attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt
    57241 gtaagataaa agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa
    57301 gctgtcttct agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc
    57361 tcttagatat aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta
    57421 gagaaacacg tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg
    57481 gcatgttgat ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga
    57541 tccatgtgat tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct
    57601 cgcataaacg gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt
    57661 tttattaaat tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta
    57721 tcagtaagaa acgaggagga accacaatga gtcggatgga tcgctataag gacatccata
    57781 agaaggcgaa acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac
    57841 gaacgcgtat ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat
    57901 ttgaacattt gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac
    57961 aacaaaaaaa taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa
    58021 gaaagcgatc gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag
    58081 gtatctcatt ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga
    58141 cttcagaaac ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg
    58201 gaagtgatac acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg
    58261 atggtccttc ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc
    58321 caggggtagg acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc
    58381 gtcaaacttt agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca
    58441 aatcgtttga aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa
    58501 aagatctgaa tctggatggt gtagatatta aaaaaggggg ccagaagatg gatggacatg
    58561 ttcttttgca gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac
    58621 gccaacagca agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc
    58681 gtgcacctta tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt
    58741 tcttgacgaa aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg
    58801 tgccagtaga cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa
    58861 ttgataatca aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa
    58921 gatcaagaag aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa
    58981 aaacgctttc ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct
    59041 gaacttcaaa aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga
    59101 agcatcaggt atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga
    59161 agaagcaaaa aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt
    59221 tgcagatacg ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt
    59281 catccagaca agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg
    59341 taagattgag atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga
    59401 tcgatttggc atcaactggc agattaacca agagtgacag ctaaagatga atattttctg
    59461 gaaacatcaa gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg
    59521 actatacggt atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc
    59581 cgcaaaaaat taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct
    59641 tcacaagcaa aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat
    59701 gaaatcagcg atccattgtt tgctggtgaa gtaaccatca cttatggttt tggaaatttg
    59761 gtagatatgg ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat
    59821 ttgcctattt tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt
    59881 tcgatcgtaa aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat
    59941 cgagaaggtg aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa
    60001 aagaactatt tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt
    60061 aagaatctcc aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag
    60121 aacgctgatt ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga
    60181 aaagggattg atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt
    60241 tatcagctgc aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt
    60301 ttaattacga caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa
    60361 acccaagaag agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac
    60421 ggacggattc ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg
    60481 ctatctagtt tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt
    60541 gatgctgctc aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt
    60601 tacattacag aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt
    60661 ttaggaatag aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg
    60721 aaaaaagttc aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc
    60781 tttgcgaagc tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg
    60841 gctatgtttg ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa
    60901 ttaaagctaa aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc
    60961 atcaagtcaa aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca
    61021 gaagtagaac tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga
    61081 acgttgatca cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa
    61141 attctcaaag aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat
    61201 cttaagcaga agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga
    61261 atcactcttt gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg
    61321 cgctgggaag ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta
    61381 gagaatatca aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag
    61441 gtagactttt cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac
    61501 gatcaattag gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc
    61561 gctacatgct tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag
    61621 ctgactaaaa cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa
    61681 ggttttactg gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca
    61741 atcggttttt cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa
    61801 gaaacatcaa gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg
    61861 aatatttatt ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat
    61921 caagcaaaaa cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga
    61981 aaaaagtgca ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc
    62041 aagcatttct aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa
    62101 cagcatattc accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt
    62161 atttttttca taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg
    62221 tggtggtagc ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc
    62281 aatattttgg ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt
    62341 tgtcattttt tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac
    62401 ttggatataa tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa
    62461 aaatgaaaaa gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag
    62521 aagtaaaaga attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg
    62581 atggttctgt acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt
    62641 cgatcatgaa tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc
    62701 gactaaagaa attatcaaaa tcaacgcgaa agttatttta cgtcactcgc caggcgaaat
    62761 gatcggtgta aaagatgcaa atgcattaga tatggccgtc aaacagcctt cacaagcagt
    62821 attcaatcaa gaactctatc ctgaaatcta tgaaaaagcg gcgattttag caattaattt
    62881 agctaaaaaa catccttttc ataatggcaa taaacgaact gctcttgttg ccatgttgtt
    62941 gtttcttcaa ttgaataatt gtccagttgc tttttctcgt caagaagctg ttgattttat
    63001 cataatgatt accactagtt cattggattt cgattcacta aagtccaaga taaccagtta
    63061 tttacgacaa accgcaataa aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc
    63121 atgtcattaa ggaatatgct gattttttta tgtttaatca tacaaaatag ttttttcata
    63181 aaaatatgga aaatatggat taattttgaa ataattgatt taaaaggaat acaaaagagt
    63241 gaatagtagg aaatagtggt ttagaactag tgggctgatt ttttatatat tttagtttac
    63301 ataatatata ttatacaaag tagatttaaa aaatgataaa cctctctcga acggtttttt
    63361 atcaaaaatc gtcatttttc catcaaaatc tgcttatgca aaattataaa aaaattttgc
    63421 agtttttctt actttttttg tcgtttaatt gaatgataaa aaccagtttc tttattcagt
    63481 taatcaaata tgaacgaatt agatatgaat cattgtattt gccgttgcgg aaggattttt
    63541 taattaacca cagataaaca ttgataacga ttcgcttatt gtaatcaaca gattaaattt
    63601 catatgttca tatgtacgga tacattttcg gaccgattaa ttttaaccat tctgtttatt
    63661 tgcttaccta ttagatatca ataaaaaact gcttaacagc tatttcagct gttaagcagt
    63721 tttaggattt ttagttcata ttcattgttt cttataatac agtgttcaat acttctctta
    63781 aagcacttgt tgatttgctg aacattgctt tttcttcttc gttgattgat aattcaacaa
    63841 cttcacgaac accattttcg tcaacgattg atggcacacc tgtaaagata tctttttcgt
    63901 cgtattcacc agttaaataa gcagatacag gcaatacagc ttgttcgtta ttcaagatag
    63961 cttttacgat acgtgcagta ctcataccaa taccatagta agttgctttt ttacgatcaa
    64021 tgatctcata agcagcatta cggactttat cagcaatcac atctaattca tcttgggcaa
    64081 tacgatggtc tttttctaca atttcaaaca ctggtttacc accgacagtt gtatgtgacc
    64141 atgcagcaac ttctgaatca ccatgttcac ctaagatata gccgtggacg ctgcgtgggt
    64201 caacttttaa tttcaatgcg atttctttac ggaaacgagt tgtatccaat gttgttccag
    64261 taccgataac acgtgatgtt ggcagaccag attcgttcca agcgatatat gtcaaaatat
    64321 ctactgggtt tgaagcaaca acgataatac cgtcgaatcc tgatcccatg atttctttta
    64381 cgatttggcg catgattgac gcatttgttt taactaaatc taaacgagat tgaccaggtt
    64441 tttggttgat accagctgtg ataacaacga tatcagcatc tttacattct tcatagccac
    64501 ctgaccatac agccacattt tcatcgcccc aagccatacc atctaaaagg tccaatgctt
    64561 ccccttctgc tttttcttga ttcacatcga tcaatactaa ttcattagag attccttggt
    64621 tgatcattgc ataagcgata cttgttccaa caaaacctgt accgacgatt actactttac
    64681 gacttgtttt tttcatgaat aaacagctcc ttttcataac tatttgttac tttcatgaaa
    64741 agtatagtct tgtttattca ttttatcaac atgttaatta taatagttgt tattataatt
    64801 tttgatggaa acgaattcct gaatacgcat aacagataaa tgacaaatgt ttacacctat
    64861 atcccctgat aatacaacca aaagtttaga actgaaaata aatccaaaaa aattcgctgc
    64921 aacgatataa taagacagca atcgcaccta aaacaatttt ccttcatatg ctttagtgaa
    64981 agattttctt cttaatgttt atttctccat tcattgggag tacatgttga atacttcttg
    65041 aataatttga ataaagaagt cgtttgttta tatccgatac gattagcgat ttcttccaac
    65101 gaaaaactcg tttcttgaat cagttccaac gcaaagtcga attttttctt tagaaccagt
    65161 tcttgaaagg aagcatcaaa atacattttc aatttattac taagatagac cggattgtag
    65221 ccaaaatgag ctgctgtttc ttttaacgta caagaagtaa aatgcttatc gatataatct
    65281 aatactctaa gcatctcatt ttctgcgcat ccatctgctg atgaaaagct ttgttgttct
    65341 aataaatgag tcaattcgat cagtaatagt gatgtataga gatttaacga acggatctta
    65401 tgactgtatg tatcaaaata aatcaacagc atattttcaa tcaaatgcgt caaacgactt
    65461 gtttttccgc cgcgaaaatg aatgaattgt gtatgttccc ctttttcttt tgatgcattt
    65521 atcaaaaaag aagaaagtag attatttgtg cttgccaaat gattcaatat ctctgtagat
    65581 aaggtttctt cttttaataa gatgttgatt aaaatatcct cttgccctgt gtattcgatt
    65641 ctttgagtag cttctttatc aatgatcacc acgtcacttt cttccatctc tatcctttct
    65701 ccattaataa tttgtaaaca tgtaccgcta tacatataat tgatttcaac aaaatcatgt
    65761 gtatgctcgg gaacttccgc atatcgacgg tgtttactga tatgaatatt tccctgttga
    65821 aatagatccc ctcggtggat ttttggcggt gtctgaagat ggtaagctaa gtttaaatca
    65881 ttgatattca ttccttgttc acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa
    65941 aatgtctaat tcagctagtt ccaattgact ccctcctttt tgtaagcggt ttctttcgct
    66001 tattagttca cgctgtactg ctattatatg caaagctatt tttggtttca taaagacttt
    66061 ctatggttgg gacatgaact tcctgtgatt ccgctattga gagaataacc acttcatact
    66121 atatttttga taagcgctta caaaaatgaa aggaacatgc ttatgaataa aaagatgatg
    66181 aaattttctc tgctgtcagt ctctcttatt ttgacttctg ctggtgcagt cacgtctgca
    66241 attcccagta tgtcagctac ttatgccacg cgttctttat ctgctgttga attattaacg
    66301 actgctccct cttttatggt cactattttt gttttgatta gtagttttat tgctaggaaa
    66361 atcggacaaa aacaaactgt gatcatcgga ttagtgattg catcgatttg tggtatcctc
    66421 cccctcttct cacaaagtta cagtattgtc ttagcttcaa gagctggact aggtattggc
    66481 tttggattga tcaattcttt ggcagtcagc atgattgctg ccttttatca cggagatgaa
    66541 cgagcctcta tgattggttt tcaaagtgca tttcaaggat ttggtgcagc tttaatgaca
    66601 tttgttgcag gacagctagt acagttcggt tggcaatata cctttttagt ctacgccatc
    66661 agcttaccta ttcttgtctt gtttgttttg tttgttccta cacctgaaac aactgaactt
    66721 caatcgcatg gcacagcccc aacaagacaa gtaatcaaaa cgaatcctaa aatgattagt
    66781 tatggtattt ttctcttgct ggtcatcgtg gtatataatg ctgtatcgat taaattagcc
    66841 acagtcctga cgacttattc tctaggaaac gaaactaatg cagcgaatat cttaacaatc
    66901 atgcaattgg caagtatggc tgccggagtt tgttttggct ggcttcagac aaaagcacat
    66961 cgctatatgc ttacactttc tttactactg atgggaatcg gctttgtatt gattgccact
    67021 gtgataaacc tgtatgtgat tgggtttggt gcgatcctaa caggaatttc tttttcgtta
    67081 ttcattcctt acttattcaa ccaagtaagt atccaagcgc ccaagtacgc ggagagtttc
    67141 aatacttcaa tcttattggt tggcgctaat ttaggtactt tcattgcacc atatggtttg
    67201 ctctttctct cttttgcttc tcttgggagt aaaacacttg ctgttttcgt caatggcagt
    67261 atcttgctgt tgattagcgc gcttattagc cttctagtag tacacaggac gaatagaaag
    67321 acagtgataa gagtagatga agaaataaaa gaacaattga caacaaaata aatttgatgg
    67381 aggtcgtgta aaatgacaaa tgaaaaacat aaagatagat ggctttggta tcctggagac
    67441 tttgagatcc gccatggact gctacaaaat ttccaacggg aagaacgagg ttttgactgg
    67501 ccagcgtact ggtacatgga tgattgccat cggaacgtca agtttaagag atattacttt
    67561 cttgatcaac cttccatgtt taaagtgacg atccaaggag ttgggtatgt agaaattaat
    67621 ggacaaaaac atccatgtgg aaaatggctg acttgtccag ctggtaaagc aaaaattcgt
    67681 atctttgtag gacatacatc agggctacca gcgatgttta tcgagggaga cgaagtaaaa
    67741 tcagatattg gctggacagc aagtaatttt attgaagaat atccagctgg ctggagtccg
    67801 ctttatgtcg atatcgcaaa agatccaaat caaatctatt atcaaaaaga atgcgtccat
    67861 ccagtcactg aaacggagat tggcggagga atcttattcg attttgggcg agcagtgaat
    67921 ggctgtgtag aactaatatc tctggatgac catatcgaat ctatcactct atgttatgga
    67981 gagtccgatg tagaagctat ggatatcgat tattgctact ataagcaaat aggaatgaca
    68041 agaaaaatga aagctcgtaa acgcgctttt cgctatttgt ttataccaga ggtttctact
    68101 ggaatggttc aacttcaagt ttttcatgaa tttttatctc tttcgaaaca agctgctttt
    68161 tcaagcgatt cttctttact gaatcagatc tggtcagtat cagaagaagc cttcaagtta
    68221 tgtagtgatt tgttttttat cgacggtatc aaacgagatc gctggatttg gtctggagat
    68281 gcgtatcaat cattcatgat caatcaatat cttttttttg acgaggaaat caataaacga
    68341 acgatattag cattaagagg acaaaatgaa atcaagcagc atatgaatac tatcgttgac
    68401 tattcgatct tgtggttgat tggtatcgaa aaccactata tgatgacgaa agactatgaa
    68461 tttttacgca tcgtctaccc taagatgcaa tcattaatga gatacttgat ggagcaaacg
    68521 aatgaattag ggtttattta tgggagagca aaagattgga tatttattga ttggtctgaa
    68581 atggataaag aaggaacgct tgctgcagaa caagtcttat tactgaaagc ctatcattcc
    68641 atgatcactt gcggagatat cttagctgaa acatatggag agaacgaaaa ttatcatact
    68701 catctctatc aagaaaaata tcaactattg aaacaaaacc tatttgacta cttttgggat
    68761 gaagaacttg gcgcttttat cgattgctat gaatctggga gaagaaatgt gacgcgtcat
    68821 gcgaatattt tcgctgtttt attcgatttt gctaacaaag accaacagca atcgatctta
    68881 aagaatgtct tattgaatga cactatcaca cagattacta ctccatattt caaattctat
    68941 gaacaagatg ctttatgcaa actcggacag acgaatatcg tctaccaaac gattcttgat
    69001 tattggggag ggatgttatc tcatgatgcg gtaactttct gggaagaata cgaccctact
    69061 caaacaggaa atgaaaagta cagtatgtat ggagatcctt atggaaaaag cttatgccat
    69121 gcatggggag caagcccaat ctatctttta ggacgctatt ttatcggttt gtatccaaca
    69181 aagccaggtt atgaagaatt tatgatacaa cctaatctag attcatttga aacactgaat
    69241 tgtacgctac ctatcaaaga tggaaagatt tcgcttgaaa aaacaaaaga taagatcgtg
    69301 attacttctg atagaacagg cggaacagtg aaaatgaatg gtaaaagtta tcctcttcta
    69361 gcaaaacagc cacttgtctt aacaagctat tcaaaaataa atgcataaaa caaaaaactg
    69421 cttgcgacat atcagaagac tttaaatctt cttctgatat tgtccaagca atttttattt
    69481 tgaagtttgc ttaattctgt tctttagaaa caatgtttgt tctttttccg gcaaaaagaa
    69541 agctagataa tacgacaagt aaaaagaaag cgatgattcc aactgtcaag gctatttgac
    69601 cgtattctcc tagtttccca agtacaagtc ctggtactag ataatcagta tcggcaaatg
    69661 tagaagaagc gattttaaga tctcctaata ctggaaggat aaataatggc agccaactaa
    69721 tcaataagct attgaaagca gaacctaata ccgcccctct tctaccgcca gtcgagttgc
    69781 cgaagacacc agaagcagct ccgcagaaga aatgtcctac taccccagga atgataactg
    69841 tagtttgcaa gcctatcata gcaaacatgg atagtgttcc tacaaagaag ctaacaaaaa
    69901 agccaattaa tacagcatta ggtgcatatg gaaaaacgat aggaacatct aatgctggtt
    69961 tagaatcggg tacgagtttt ttagcaatcc cttggaatgc tggaacgatt tctgccaaca
    70021 ccattcgaac cccttgaagg acgataacaa acccagctgt gaatgttcca gcttggatca
    70081 gtgcaaagat tacagcgttg tctccattgc ttagttctct ttcaacaaat ccaggaccag
    70141 ctaacaaagc aagtgcgaca tatacgatcg acatcaagag catgatcgat acagtagaat
    70201 ctcgcaaaaa gctgaaactt ttaggaatct ttatgtcctc tgtagaacgg tctttgtttc
    70261 caaaaaactt tccgatccat ccactagaag cataaccgat atttccggta tgccctaacg
    70321 caacttgatt gtttccagtg atgttcttca taaacggttg acaaagagca ggcgtaatag
    70381 ttaatagtgt tccttcgaag accccgccta ataagatcat ccacaaattt gcagtaaacc
    70441 ccgcgcttac taaaatgact gctgttagac aagaaacata aagcattgct tgacctgtaa
    70501 gaaaaatgaa tttatatctt gtgaatctag caagtaaaat attcacgatc atccctacta
    70561 gcatgatcaa agcagtaggt gtaccgtatt gttgcaaagc aatcgccact actgcttcat
    70621 tgctaggaac tactccttga gtatgcagag ctgtttggaa catcgaagca aaaggggtta
    70681 gtgaattact gattaaacca gcaccgccga tcagtactag gaatccgaca aatgttttga
    70741 tagttccttg gatcacttct gaaaatttct tcttctgaag aacgagacca agcagtgcaa
    70801 tcaaagaaac gaggatggag ggctgactga cgattgacac aaacaaattc aacaatttat
    70861 ccattgatag ttcctccctt gaatcatttt tattcttttg acaagatctt cgttactttt
    70921 tcttttactt cttcgctgtc aatgatcgat tgcaaaggta cgagcttttc atcaggtata
    70981 gaagttagcg tatctttcaa agaatgctca atgaagaaat aatcagccat atcgctagat
    71041 acacttccaa catccgtatg acttacttca aactcgtcca catctgctcc aagatctgca
    71101 agtgcttgtt tgatgttcat ctctaccata aaacttgttc ctaatccact ttgacatact
    71161 gcaaaaattt tcatatcatt cgtctccttt tcttatgatc gctaatattt cttcttttgt
    71221 tgatgcgtgt aataaatctt gaagattttg tttattagaa agtagctttg ttaaatttgc
    71281 caaagcccga agatgtgcct cattatcgat agcagctaaa cagatgaaca aactaatggg
    71341 atgggctgga ttatcaagca gatccacagg ttgttgaagt ttcagcaaag acatccctac
    71401 ttcgtttacg ccatcttctg gacgagcatg aggtaatgcg atgtgatcgc caatatggat
    71461 aaacgcacca tactgctcca cgcgctcgat catagctttg atataacttt cttctatttt
    71521 attttctgat aatagcggct gtgcggcaaa tgtgattgct tcttgccagt tttttggttg
    71581 atccgataat tggatcattt cttctgttaa taattcagat agcataggac gttgatcctc
    71641 cttcttttct aaaagtttgt tcattttacg atttaatact tgatagagct tttcttcgtc
    71701 tacgccttct tttaattcga tataaggcag tagcgccgac aacaattctt gggcagaagg
    71761 cattgaaaat cctggtatca gccaatctct ttgtacttga ttgatcagct gatttttttc
    71821 caagtcagtc atgattggat gcagaacata gagagacttt ttcttatcag taagtgtgag
    71881 aggtacagta gaaaaaataa tatcgtaaga agtttcgtca acctcgtgta agcggtcagc
    71941 tgaattagtc tctgtaaaaa agatcatcgg gaataattgc tgaagttcac tttttaagat
    72001 caatgaagag ctaatgccac ttggacagac gatcacggct cttatttttc tatttctttc
    72061 ttctgcgtcc gcttttctga tctctccgcc aaatagtata gtgaaaaaac caatctcttc
    72121 ttcagggatg ctcttcccta ttcgtctttc taacggaagt aatgcttttc ttgtcatttc
    72181 gtagatggaa gcatattgat gcttaatttg atcgatcatc acattaggta aataaaaaga
    72241 ataggaaata cgaaaatagg cagggaccaa gtgataaaag acattcatca ataattcacg
    72301 aaacgaagca aattctacgg ccatcaggaa ttccatgcga tggatgactt ctgaagaaca
    72361 ttccagcaaa aaatcaagtg caggctcctg gacatctcct tcaacgatcg atgctaagca
    72421 aagagagaaa aatataatct ccgaattttg atgttcggaa tagccaaggc cagtcaatac
    72481 ttgtcgacta atgtcagtga ctgcaagaga agccaacagt tcagcatctt ttaccagttc
    72541 catggatgtt tttccaattc gaatggttgt caaactcaaa taataagcta attcatccat
    72601 tcgatttggt gcgaatcgaa gatctgatag tgaaatcgtt ttatctagca aatctctaac
    72661 tttggcgtaa taatcaatgg aaagggttgc ggttaaatac gtgagcccaa atcttccagc
    72721 aagtgactgc atcaaacgag cagtgcgatt ttttgcttct cttcttaata ttgcttctga
    72781 ccctagcagc ctaaaaccag ttttcctagt atacgacagc tgacaatctt ccacttctaa
    72841 ttcatttctt atctttttga tatctgacag gactgtccct ttagaaacct gaagaaaatc
    72901 ttgaaaatga aaaacagaaa cagacgttgc agtcgaataa accatcaaat aaagaagatc
    72961 tcttcgctct tgttcggtat acacagcttc aaatcgagta atatccaaaa atttttctgc
    73021 ccagtcgatt gctcggaatt tctttatacg gatacgggta tcatccacat attcggcaaa
    73081 aggagttaat tgtttgatcg cctcgcttgt atttacttcg atgatctctg ctgctttttc
    73141 tagactgatt tctcttggtg ttttcaggag ataactaatt ttgtagttca cagcgctgtt
    73201 cacctcctac ttatattcta gtatggtagc gcttttaaat cgaggggtgt ttggtacaac
    73261 ttacagttgg atttttttta cgactgtacc gaacgatttc tatcgaatgg atacagaaaa
    73321 aaagcaggtg accaaatgtc tcctgctttt atgaattgat ttcgtccgat caatgatgat
    73381 catgtttatt ttttgaggtc agttcttcaa atttttcttt gacatcttca accgcttttt
    73441 cgatatcttt ttcaaagtga ttgggctcat taggctttgt ttcctcttct acagaatttg
    73501 aaccagataa agctgtttct ttattttctg tttcaccaga gtttgtgcca gctaatgatt
    73561 cttctttgtc ttctgtttca ccagaattag ttcctgctaa agccacttct tcttctgttt
    73621 taggggccat tgaacctctt aatcgtttgt gtttttcacc gtcataattt gtcatgttgg
    73681 ttcctcctag tagttctata ctttttcatc gtacaataag acagtttatg cgtcaaaaaa
    73741 caaacccgat tcttacaaat atgtcatatt tttccttctg attcttgaat gcttttgatt
    73801 ccttcttcca aaattttcat ttgtaagatt gtttcttcat ctttgatgac tttttctgcg
    73861 ccattaacta atgtctcgta aatcccttcg tagacacggc tgtaatcacc aacctcggaa
    73921 attacttttt cttcatgata actcccttgt tcatctatat aggtcaatac accataatgt
    73981 tcgggcaaat cgataccaaa gtcttcatga tcaggcatgt aaaacatttt cagatgttct
    74041 tcttgtcgat cttttgtttg tttcacgaac atcccttttt ttccgtaaac gacgaaactt
    74101 ggacgttctt tgatgcggaa ataactggat tttatcgaaa ttttcatatt tccatagaaa
    74161 aaatccagat cgaagtaatc attcattcgt cctttcccta aaagttgacg tacatcatag
    74221 ctgatatcat ctggttcgcc gaaataagaa agaacttgat ctactgtatg acaagcatgt
    74281 ccatataaat agctgttcgc agtagaaaat tcatgcgtat tttctggtac ttccggtctg
    74341 aaataatcat aatgcatttc tacttctaaa atatccccta attttccgct ttcgattact
    74401 ttttggactg tcaagaagtc agaatcgaac cgtctgtttt ggtaacattg gataaataga
    74461 cctttttctt ttgctaatgc aaataactct tctgcttcct ttgacgtttc tgcaaaaggt
    74521 ttctctacta gtacattctt accatgttcg agtgccattt ttccatattc ataatgaaat
    74581 tgactaggtg tagtgatgac aactaattgg atctcaggat catcccaaag atcagacagc
    74641 tgatcagtat attcgatgtc ttcgaatgtt ttccacactg gttcagatgg ggaaaaaatt
    74701 tttttgatat tgattttgtt cgtaagtttt cttgaaaaag gcaaatgata gcgatttgta
    74761 ctctttccat tgccaagata agcgattgta agcatgagtg gtgcctcctt ttattgatgt
    74821 tttcagtata tcctagaaaa gcgcagaaag tatttataat agctattctg gtaaaaaagt
    74881 tcagaaaaac acttgttatc attcggtttg gtgaaattaa tgttcaaagt aaggataaaa
    74941 atcaaaaaga tagtagcgga accaagtgtt tatcagtaag atagaatttg gaggtcagat
    75001 catgcttatt gaagaaaaac taacaaaaca agagttgttt accacgacag agaaacggat
    75061 tgtcgattac atccgtagga atatcgaagc tgcagtctac atgacgattg aagaattagc
    75121 aaaagctacg tatacttccc attcagctat cattcgttta tgcaaaaaaa tgggattcag
    75181 cggatttaaa gaattccgtt tcgagctggg gcgggaagtt catcaattga ttgctcagtt
    75241 caatcaaacg attgatccta attttccttt ttcaagtgaa gatagcactc agcaaattgc
    75301 aaagaaaatg gcggatttat cgatccagtc aataaaaaaa gcacaattgc agattgaaca
    75361 tgaagattta gatcaaatcg gtaaagtatt gaacaaggca cagcgaatct ttctttttgc
    75421 aaaaggtgat tctcaaatca cggcaaggaa attccagaat aaaatggtca agttgaataa
    75481 gtttttgatc atggctgaag aatacagtga ttcttcttgg aatgcagcca atttgactag
    75541 cgaggattgc gccattttta ttagctacag cggtcgcatc catcattatg aacgaataat
    75601 gacctatttg aagcatgtag aggcccctac cttgctgatt accggaaatc agcattcaga
    75661 aatggccaaa caggctgata tgtgtcttgt tatatcgcag gaggaatatg attttgctaa
    75721 agtagcgact ttctcctctc aaattgcctt cgattacgta ttaaatacgt tattctcagt
    75781 gatatattct caaaattttg aagagaatat ccgcaacttg aaaaacaaac aagaattgat
    75841 gcaaaaaggc cttcttaaag aatatcggaa aacttaagaa aagatcctca tttagtaata
    75901 agaaagatag tgtttgatag gctctctttg atatcatcat aaaaacaggc tgaagttttc
    75961 tttttcaaac ctcagcctgt ttgtttacgg aacgattcga atagatatat tatagaaatg
    76021 aggaatagct aacttctgtt tcttattttg aacgattgac gaaaaagata tataagaagg
    76081 aggaaaatca gtatacatgc agctaacaat ccatacagga aaaatcgttt gttctcggat
    76141 actttctgta cttctttttg aacttctttt gcatgataag gaacccggtg ccctctgaca
    76201 agtaagcgat gactgttgac catataaggt gtacaagtta ggagtgtcac gaaatcctgc
    76261 cctttttcga ttctcagatc ttttgtatca gtcggttcta ccgtcttgat ctgatcgact
    76321 tgataagcga gtgtccgtcc attgatttcg atatagaaag aatcacctaa agtcagtttc
    76381 ggtaagtctg tgaacaactt tgcttgaggc agtcctcgat ggctggaaat aacggcatgt
    76441 gtattttctc cccccgtagg ataagacgtt ccttccaata atgaggcacc tttttctagc
    76501 agcacagtat tcgtttcatc aaaaattggc aaatggacat tgatctcagg gatcgtcaaa
    76561 ataccgatcg tatgtttctc aaaataggtt ctatcctttt tcgcaggttc ttttttctta
    76621 gtaaagggat ctgcacctgg atttccacct tcttttgcta attgctggtt tttctttgtc
    76681 atgttttctt ggattttagc catgacttct tcattttctt tgaccgcttg ttgctgataa
    76741 tgagagatga tctgctgatc cagataatta ttcagcgcgt cgctaacaaa tggataagct
    76801 agtatcccta ttcctgagag aagcaagaaa agcatcagca gatctagaag tttccttttc
    76861 tttggtttca tttgtgttct ccttgtgatg actgtttgat aataaaagaa aaaggagcat
    76921 ttgcgtaatc cgctgctcct ttttccaatt cttgcaaaaa gactaaatct gactgtgctt
    76981 gcgtctagca aagtacagtc cagcaatcag tagaaggact actcctgcac cgatatacac
    77041 atagattccc ttaccgcctg ttgaaggaag tgtacctttg tgtttatttg gtattttttc
    77101 aggagaaatc aactgtcctg ctgttacata agattgttca tcgatagtaa atgctacacg
    77161 gtttgttaat ggaacatatt tttctggcgc tttcgtttct tccagatagt acgtgccata
    77221 ttttagacct gtcacatcga ttaaaccgtt acttgtggtt gtaaaaaccg ttgctgattc
    77281 tttcgccgat acccagctga cggcttttgt ggatgggtcg atcgataaat atttcgctgt
    77341 gtcactatct tgatcacgaa cgacgaattc tgctccagca agtgtttggt ctgatgtaac
    77401 gtcaccatct actttaacaa atcgtttgcc cccagtaacg acatcgactg acggtggtgt
    77461 ttgatcattt gtatgcccgt tatcgacatt tgcttggtta gaaaatcctt tggttggatc
    77521 tgctttttcg ttcaaatgca tatagtaaac gaatttcaat gtaccgccag gagttaatga
    77581 aggaatataa ttcggatcaa ctgaaaccgt gaatccgtct gtttgctcag tgacagaata
    77641 atttactggg tcgatttctt tatttccatc atataaggca taagcatacg ttcctgaaga
    77701 atcattatca aatgttaaag cagcgtcatg agtatcgata agtttgaatg ttgtgtactt
    77761 gttttgcgtt ccttctttat cagcgatacc taatgggata ttgacagaaa tctcatattg
    77821 aattttttca ccgattgcga catcttttcc attcaattga ggtgttgttt tatcaacttt
    77881 agacgtatca tttttgatgg tcttttctac tggtgtttgg ctatttgcca ggatctcaaa
    77941 aggcgtgatt gtttgctttt caatcatttc cgcattatca ggagctttta cttcttctaa
    78001 attatatttt ccaacttcta aatgattaac gatcaactgg cctttttcaa tagatgcctc
    78061 ggcaaagtca ttgttgccga tgtcataaga atgaccagta atgaaatgtt tggctttggt
    78121 ttgatcagtt gtccaagtgt acaatccatc tgtgacactt tggatgtatt ttttgacgct
    78181 tggtgttcct tcttctttag aaataataaa ttctgctcca tttagtgctt cgttttcggc
    78241 agtaccgatt tttgtaactt tcaacgttcc atcattaccg actgtatttt tagggtagag
    78301 atggatagta tctagttctt ctgtcccgta tttataagag ccatctgctt gtttgatcat
    78361 ctcatataca gggaaagcta aaaccatgtt tgcggcagct gacactccgt cttttggttc
    78421 ttctttgatc gtgtagactg catctttccc attttgtttt ttaggtaaag ataaagtgac
    78481 atttccatca gcatctgtcg ttcctgaagc aactggtgta ccaggagtca aagactggac
    78541 tgcttgtttt gctgcatcca cggacgctcc tttatctcgt tgcgcataaa attcttgagt
    78601 gacgttataa actgaaaatg aaatatcggc taatccttgg tattgatcga attcgctcat
    78661 ttctttcccg ctgttttgga ttaaaggatc gggtaaatca gtcattttct ttttatgaag
    78721 gatgacttga gctgctgtct cctctgcaaa cacttttttt gcgccgaagc tgtttgtgag
    78781 taatggtaaa ataaggaaaa ggactcctaa cataacgttt atttttttat gatttttcat
    78841 tttttcactc ctgttctttt tttgataaac aaccagattg caaagcttgc gaataccata
    78901 ccaacaacgc ctaaaagtgt atttttcgtt tcgtttgttt ttggaagaaa tggacggcta
    78961 ttttcttttt tattgactac tttcaatata ctgtccgcct ctttatcctc agaaagaaaa
    79021 gttgaaatgg taaacggaat ttctgtttca cttaaaatat aaccagaagg tgcttcgatc
    79081 tcttttaatc gataacttcc tgttttcaac ccggaaattg aaaaagcgcc atttttatcg
    79141 gaaatcaggt gaagcgcatc tgattcgttc tttgtccact tgtatccgtt ggctgtttgc
    79201 tggaggtaat ttcctgcttt gtttttaata aggaatactg cgccagctaa tcgtttatct
    79261 ggtttatttg tctcgatttt gacaaattgc ttactccctg tatatacaga gactttcttt
    79321 gtactgacac caaaaccaaa atccagtgtt ccgttgttgt tgatttcctt gttcgcctgt
    79381 gctgtactgc ttagctgcat ctgataagaa atggtcagtt tttttccagc atatttttcc
    79441 aacgaaggga tcgaaaataa aacatcaaat ccgtgaggtt tcttgtgtat gacaaagcct
    79501 tctgtcagct tttctccatt cgatgaaatc gttaaactat taggtaaaaa cgttaatgct
    79561 tcatccgcac tatctgacaa ttcgaacttt tgatagtcaa ggatatttac aggaattgtc
    79621 gtatgcaagg aataagtgat tttttcacca atcgtaaaat catttctagg ctcttctaat
    79681 accttctcaa aaggtggatc agggtagtcg ttttcttcat ttttaggata caaatggata
    79741 gttgaaagtt tttgattgtt ttgtccatgt acaggaagaa caactaccat attctctgcc
    79801 ttttctttga cgacttctgg tactttggat tcaatgaaaa gatacgcttt atctcttttt
    79861 tcttgatctt tagcggccag agaaaaagaa gcgataccat cttcgttgtt aagagttgta
    79921 gttgttgctt ctgcggtaaa cataccggaa gacgcaccgt tttttgcgat ctctgcttgt
    79981 gcttcttcta ccgttttgcc cttttcccgt agatggtaaa aagaatctgt gacatcataa
    80041 acttggaatg tgacaccatt taatcctcga tacgtttgta ataaagcttt ttcttgtccg
    80101 tcatttggat gatttttcgg cagttgcccg tttgggaaaa gcaatttgtg taaagtaatc
    80161 tgaaccattt ctgtttctgt ttctgttgct acctgagtaa aagctggttt aaatagtaac
    80221 aagaagagac acatactaag ccaaccaagt tttttcatat ttagctgccc cctctttctt
    80281 ttttcaaaaa aagataccaa atagaaaacg cacaaccaat catccctact agatagattc
    80341 ctaaacggcc aattcctccc gtttcaggta atggtacttt tgcctgattc gtgatgtcta
    80401 aagaaatctg gttgtttttg gctcctggtg acagaacaga ttcatgatct tgtccatcca
    80461 cttgaattga cccatcttcg tgtataacta tagtaactgg ctcttttaga ccttggtatc
    80521 cttctggtgt aaaagtttcg gtcagcgtat aagttccagg ttttaaattt tcgaatagaa
    80581 aggtatctgt ttcttgtcca tcttttggcg attctaagtc catttctggt ccctgcagtc
    80641 tgaattttgc tccttttaat gtctgtccgt tgtcttcttt tttgtgtacc gttagatcaa
    80701 acgcttttag tcgattttga tgagtgagcg tccatacatt atttgtcatc tcggtatttt
    80761 ttcccgtgta aatgattttt ccatatttat cgatttggaa ttcataattt cccggcgaag
    80821 tatcatatcc ggcaggacca gctgtttcaa cgactcgata tttaccaggt gtgagtgaat
    80881 caaaactggc aagacctttt tcattcgttg tttggctgtc aattggctga taagtaccat
    80941 ttgcttcttt tttctgtagg gaaaatgctg ctcctttaag atttatctct ttgtccgtcc
    81001 cttgcatcgc atacttacgt actgctacag gaacttcaac aaaaggattt tcaatagtca
    81061 actggatcgt atcatcggaa gtagtgactg tttttccatc aatggttacc gtaccatcag
    81121 aagcgatctt gatttcccaa gtagtctttt tgcttaatcc atgcccttct ggagcttttg
    81181 tttctgtcag cgtataggtc atttcttttt gcaatttgac attttctgga agagaatagg
    81241 ttccgtcgcc atgatctgtt agtaaagtat caatagaatc tcctgttaat ttgaaaacag
    81301 cgccaataag atccttttca cctgtagagg aatttttcgt tattttcaag tttaacggtg
    81361 tgaattgttt agtatttttc catgtcattg catctatttg ttgagaatcg tatcctggta
    81421 caggtaattc tttgattgtt tggtaactga atgcttgacc ttgattattg tattgaggta
    81481 gtgataatat ctcttgataa ctttctccgc tatttgcaga taatttgtca atgtctgcac
    81541 gttcccacgt atttgttgta tctttagctg gtttaatgat tcgaatatat ccgtttttcc
    81601 aagctgcagc atttgtcgta tgttcccgtt gaatctcaaa agtaacttga tctggacgat
    81661 cagctagatt gttgtcaaat tcttcccata actttttgat gtgaagactg actccgggag
    81721 ctttagcaga tggtataccg aattcagcta attcattggt atcaatgttt ggctggaaag
    81781 ttgtcctgcc gttcatttga taccagaaat ttggatggaa gtcctcattt tctgtttgga
    81841 ttctcacttg gtaatggatt tggatttctt ggtcttttcc taaatagatc tgattgctct
    81901 tgatggtatt tccttctatg gaaatagatg gagtgaccgt tgtaggactt gtccccacac
    81961 tcttgactga aagtgtacca ggctgataaa tgaatggttc tgcgattgga tcatttattt
    82021 gtccattgct tacagttgct gagatctgta cagctttttt ggctaggtat tcagagatat
    82081 ctgttgcatg atcagctgat tcatagtaaa gatcgccttt ttcatctgat gaaaccattt
    82141 gtcgcatacg agactctact tctgcttttg agagaccagc tgccggatcg ctttgaagtt
    82201 ggatgccaag accatgtatt tcgattcctc gttctttgag tgccatcgct tctccgatgg
    82261 ttgcgataaa cgtactgtcg attcttctgg atagattgtt ttggtcaggt gcatcataga
    82321 ttcttgagat tagagaagta tttcccggcc gatcttgcgt attagaaaac tgagttccgt
    82381 aataattgct gcttgattgt gcgtgtaccc gctgtacttt ataggaaaat gttggtacac
    82441 catccgtcag caaaacgatc acttttttat gtccatttgg aacggatagc atgcttcctg
    82501 catctcttag tgctttttgt gtaaaagtac caccatttgt ccgtgaaggt gtaatggatt
    82561 ttacttgatt tttcactgaa tcaaatgaac ccatctgtac tgcaccgtta ctgtagctat
    82621 atccttcgct tgagtagccg acatatccca tattgatttt gtctgtgata ccgctatctg
    82681 ctaaagtatc gacaaaacga tcgacaccaa tctttacttc accgatccga ttattgtcgt
    82741 tcatacttcc tgaccagtct acgaccaata cgagatcaag aggcgtgata tctttttgta
    82801 catttccacg agcattcaaa taaacatcaa acaatccggg tgtacttgtt tcctttgcat
    82861 actttcgtat cgcatagtct gcttgattac cggttcctcc atattcgata tacgaatggg
    82921 tccgatcatt aggatctcca ttccaagaat ttataccatc ccattgattt gttccgtttt
    82981 tattgccttg atgatcaaga acatttgtat ttcctgtagg ttgccaactg gctttaggat
    83041 aagtgccctg atcatctgtt gtatattctg taggaatcgt ttgattagat ggcacactca
    83101 cagctggcaa ggataatgta ggcaatgtaa atgggctgac agaattttcg ttttcttttg
    83161 atgattcttc ttctatttcg tctggctttg gtactgacac atctgtatct ttcttatttt
    83221 ctgtctcatc aataatgtca tattctttat tatcgacgat cagcttgttt gcctggctgt
    83281 ggtaaagtgc tggatcgatt ggaaaactca gatcgatagt ttgtttagtg tttgatgaga
    83341 tttccaacgt aattttcccg ctatttacct gataagcata gccatctcct tcttttcttt
    83401 ccacatcact taagtaattt tcgactagac caatttcttt ttctatcttt tcagcactgg
    83461 tgttattcgc atttagcttg atgttcagtg ctttttttcc agactgatcc gaaatgactt
    83521 cagctgaaat tgtttctaaa actgttggat catctgtagt gtctgctatt gcagataatg
    83581 gcacaaagtt tgataaactc aatattatca gcatgaaaat aactttcagt ttcttccctg
    83641 tggtcgtcat ttttcccctc ctttttcttt ttttctgttt tgacgtgaat agtgaaaatt
    83701 attaaaataa acaggcgtta cataatttta tttattttaa tatgataatt attatacgaa
    83761 gggcgctaaa gggaatcaca ccaattttca taccaattgg tttcatttat gaagttgatt
    83821 ccttcgatta atgagcgttt cattgaaaga aaagggttga gggagaaaaa catatgatca
    83881 ggttgttgga acgaaactat agcatgagta accataatag tcgctttttg tttctcatga
    83941 gcttctttaa ctagtaattt gacgacttca tatgcatgat ctgtatccaa actagctgtt
    84001 ggttcgtctg ctaagatcaa gcttggctca ttatataaag cgcgagcaat tgccactctc
    84061 tgtctttctc caccagaaag gtctttagga taactatttt taagtgactg gatatctaaa
    84121 gattgcagca aggaatcgat ttttgttgaa tcttcttttt ttgaagtaac ttggtcaact
    84181 agttcaaatt gttcctttac cgttaaaaaa ggaatcaaat tagagctttg gagaataaat
    84241 cctatttctt taaagcgtaa atctgctcgt tttttttctg gaagctcagt tagtgagtga
    84301 ccgttgatca ctatttctcc ggaagtcggt gtttgcaatc ctcctgaaat ggtaaggaaa
    84361 gtacttttac ctgaaccaga aggaccaatg atgctgacga attctccttc ctttacataa
    84421 aaatcaattg ctttcaaagc tgagaccttt gtatgaccag aaccaaatgt tttggtaact
    84481 tttttcatcg ttaatatttt tttcattttt attaacctcc tattgctgta attgggtcta
    84541 ctttggttat cgtacgtatc gaaaacaatc cgcctagcat tgcgacaatg atcaaaatcc
    84601 cactatatag caaccattgt gaccaaaaaa cagcaaaagg catcgcgctt ggtaaaatca
    84661 gactagtcaa ataagcaaac aaaagagcaa gcagaacgcc taccacccca acaataaagg
    84721 actgtgctac taaagattta gcgatgaaga aatttttgat cccttgtgct ttcattactc
    84781 caaaaatagc agtcttctga agtgtcatca cgtacatgaa aataccgacc acggcagcaa
    84841 ccactaagaa caaaaagtat atcatcgcat ttaaggtcat attttgggca gaatagccag
    84901 gaatactttc aatgaatgtc ccaatagtta ataactgtag acccttcgat gctttttctt
    84961 tcgaaatttt agctgaatcc tttattacga tcccattgat cggctgttct tcttcagaag
    85021 caaacggctg ttgtccatac ttcaaagcag tccacgtatc tagggacgca tagatgacgg
    85081 gagaaactgt gtaataagtt tcaggaaaga taccgacaat cgtcaaagga tcgtcgtaac
    85141 tgccaatttt gatcgtatct ccaattttat agcctgaatc agccagattt tgagagatga
    85201 tgatttcatt ctttgtttta aattcatgcc ctttcgtgag ttttggtaat aaaaatgctt
    85261 ctttcgttgt gccgaaaact gtaacatttt ctttgttttt tcctttgatt gctccgctgt
    85321 acaatccgat tggtgctttc tctcctcctt caatgtattt cagatctcct cttgttaatt
    85381 gtgaagctgc aaatacttga tttgcatcct ccgacaaaac aatctcttgt gcgtcccaat
    85441 catcgattgc ttttttaaac tcttctgaaa gtccattcgc tagtcctgac aacatgaata
    85501 cgacatacgc aatcaagaac ataataccga cgatcaagcc atatcgtaat ttagaatagc
    85561 gaatttcttt gatagctaga aacatttgtt tttcctccct atgatagatt gatagtgaca
    85621 aaatgtcact tgttgaatag tgtaattcta aagtgacaat ttgtcacttg tgttgttttt
    85681 ttcttatcaa taaattgtct aagacatctt tcgataaaac cttaacatga gtcataaaaa
    85741 atttatttaa gccttattta tgctttccat gataaactaa agtgaccaaa tcaatgaggt
    85801 gggaaaatga ttaaactatt agtagtagaa gacgataaag tattatccaa taatataaaa
    85861 gaaatactcg ctgcaatcgg cgagataaca caagtttatg atggtagtga aggactgttc
    85921 gagttggaaa gtggagttta tgatcttgca atcttggatt tgatgatgcc ggaaatgaat
    85981 ggatatgaag tgttagcaaa aatacggaaa gaaaaaatac agactccagt attgattttg
    86041 actgcaaaag atagtttgga agataagatt gaaggatttg aacgaggtgc agatgattat
    86101 ctaacaaaac ctttctatcg agaagaactg atcatgcgcg tgaaagcatt attgaaacgc
    86161 tcgctaggtc tctttgatga aaatgttctg aagtataagg atatcagttg tgatttaaaa
    86221 agcaatgaag tcttgtataa agaacaagtt ttgcccatac aaggaaaaga gtttgaattg
    86281 ctcgtttatt ttttacaaaa taagggaatc attttgacaa aagagcagat atttgaccgg
    86341 atctggggat ttgattctga tacgacgatt acagttattg aagtttatat gagcaactta
    86401 cgaaaacatc tgcgaagtac tggattggat aaagaaatca aaaccttacg taatgtcggt
    86461 tatatactgc aaagggtgtg atgcaatgaa tggagatatt acacgaaagc aacgtagtcg
    86521 cttttttgcg acaaatgtag cagcatttgc ttttatcttt tttcttttgg gattcattac
    86581 tttacagata ttaaaccaat ctgcatacag agaaacagat ctgtcattag agaaaataaa
    86641 ttttgattct cgaacagtac aattagagat acaaagatat cagcaaggcg atcccttttt
    86701 aaacccgact caaacggaac aaaacagaac aaacatggaa cagccattaa tggaaccatc
    86761 aaatgaccgt tttaacactc aagtgatctt gtggtctaaa aatggtgaga tattgaataa
    86821 agcagctatt ggtgggcgtt tcaaccaaat caaagaatta aaaatggata cgaaaaatct
    86881 gaataccatc caaaatattg aattaaatga agacagtggc tcatctgccc tctctttccg
    86941 ttcgattacg aaaaaagcgg agacgaatca agatggcgtt gcctacatcc aaattttaga
    87001 aaatacaaat caaatcaaga attcattagc gacttttcgc acgattatga ttttgtgtat
    87061 gattgttttt tggattctct ctattggtat cagttattac ttgtctagtc taagcatgcg
    87121 ccctattatt ctttcttgga gaagacaaaa agaatttgtt gagaatgctt ctcatgaatt
    87181 gcgcacaccg ttaacgatta ttcaaaatag tttggaacat ctttttacca agcctaatca
    87241 tactattatt gaagaatccg aaagcatcgc tcaagcattg tcagagacga ggcgcctcac
    87301 tggattgact tcggatttgc tgacaatcgc tcggaatgat tctgatcagc agctgctttc
    87361 aaagcaaatg atcaatacac aagaatatat cgaacaactt gttaaaccat ttcaagagat
    87421 ggccatcata gatggaaaag agtttattct ccataacgat gcaacattag aagtaccaat
    87481 tgatgaaaaa aaaatccatc aagttttggt tattttgctg gataatgcat taaaatatac
    87541 gaatccagaa gataagatca ttttggattc atctgttaac cataaagaat ggctgattca
    87601 cgtaaagaat actggccctt ctatcagtga agaagatcaa gcaaggattt ttgatcgatt
    87661 ttatcgggaa gatcaatctc gggcgaaaga gactggcgga tacgggcttg gcttggcaat
    87721 tgcaaaacag gtaatcgaac agcatcatgg acagatttct gtatccaatt atcttccaca
    87781 aggagtcgat tttaaagtcc aattgccgtt gaagcctaaa aaataatgct tatccctaaa
    87841 aaagggctgt gacaaaaatc ttgtcacagc ccttttttgt tgcgaataaa cggtgttcca
    87901 gaagtagctt cttcggaaat aagccgaaat ttctttaagc tgaccacttc tgtcacaacc
    87961 tctttagctt acgcttacga ttttttattg cggtcttcaa tgtgtacatc accgcttgtg
    88021 tcaatatcca attcttctcg gctaacatct tctgtcactt tttcaacatc ttcatgttct
    88081 tctttatgaa tcccaacttc ttcacgaata actgtatgtt tgcttacatc tacttgctct
    88141 tctttgattg ggatagtaat cgtgtcatct tccaattttt cgtctgttcc ctgtgaagat
    88201 tgatctgtta ctggtttgcg ttcgatgacg atttcttcac gtttgaccgg tacttctacc
    88261 gtttcagtat cgttgaccac atgtttgtgg atgtcgactt ctccagttgt cacatcatgt
    88321 gtatttacat ctaatttttc ttcttttagt tgaattgtat catcatctag atttggtttg
    88381 cgatcgatgt cttcagtctt gcttgtaccc attgtatcag tctcgccagg tacgtccatc
    88441 ggatcagttc ctggtgtcat attcaatgga tccgttgtat tttgaaagcc tgtcgtgcca
    88501 cctacgtcca ttggatctgt tccagtgcca gtttctaatc cagtccccat tgtgcttgct
    88561 gggctaacag tatcttgtgt atccattgta tcttctgttg tttctggctg acgatagcct
    88621 tttactgtga tgacaaattt tccatcagaa atatctcctc tatattgata taaaggatca
    88681 ttttctggtg tagccgtctc agaatcatag gtatcaaaag aaaaagtatc ttttattttt
    88741 tcccataaag aacggtcttc ttcaccatcc atccgatttt catctgtttc aacatctata
    88801 ccagacaatc cgtcaaatcc tagtctagat gctgcttcat cagtagtata aataacgata
    88861 tcatctcgtt catacccttc gttacgcaac cgttcaatta ctgataatgc ttcttccctc
    88921 gtactatagc ttccgatgac cgttaaattt ttctcttcca tgtaaattcc tcctagcaaa
    88981 tagatttatg attggtatat tgttacttat aaatttattc tataggagac gattgttttc
    89041 tacaaatatt tagattggaa tttgattaaa acaatttaat tgaaatttga aaacatttat
    89101 gttaatgaaa gtcatattct aataaaatgt catttgtttc tatatgaatt tttatgaaaa
    89161 atttcatata atttccactc gttgtgatgg tttaatttat ccaatccatc aataagcaaa
    89221 caacttatat aaaaaaggat taattctcaa tataattgct cctaccatag aataaatctt
    89281 catgtaaagt aatgaagtac caactatttc taatacttct ttaagaatta tcccaacaat
    89341 atcgttagac aaaccattat tgaataaatg gagagccaat cgattctgaa aaaatgtttt
    89401 ctaatttttc ggaaataaaa gaaagagcct cctgccatta gaacgaacca aatccatttc
    89461 attgctcatg aagtaaccac atagctaaaa agaggataaa tcaattaaaa gatcaaaaga
    89521 atgactgcac taataaaata actaaaaatg tatcttctta cttcatatct tttagctagt
    89581 acttagttaa aaatttgctt cctaagatca agacaaactg tctatcttca tttgatgaaa
    89641 tgcggtaaaa tatagaaaat gaacactatt ggagggaatt tgtaatggac agcaaaacta
    89701 gaaaacaact gcaagaaaag ttaaagcaac gtacacactt gctcccttcc gtctttcaac
    89761 agtttttaga agaaaatcgt tcttcccttt cattaggcag tcgctatgaa tacgcaaaag
    89821 attttcatct gtttactgat tatttgagaa aagtattttc tgaagaagtg gatgatcagc
    89881 tgattatcca tttagaaaaa caagattatc agaatttctt agctaaaatc tatcgacata
    89941 ctcgttcgtt ccaaactaca gcgaaccaag aaacggagca attgtttgaa aatagctatt
    90001 acgggatttc aaggaagcaa tattcattaa atcatttttt acgatttttg tatcaaaaag
    90061 gactgattga agaagagatt tctcttttgg gtacaagttt accggaaaca accaaagcag
    90121 ctccgcgata tatcgatgca gaacttttca aagattttga gcatttgttt atcccgattg
    90181 aaggctttca aacaagcaga gaagctagct ttgaagaaaa gaatagaccg aggaaccttg
    90241 caattactgc cattcttctg tattgcggat taaagatcca tgaagtagta gaacttaaac
    90301 gtaaagatgt atctttgacc aagcagattc ttaatctgaa tagaaaagaa aacagactga
    90361 ataaagtacc aataccaaaa gaagcgatgc catttctgga gaactatttt aagttaacag
    90421 cacaaaatac ggacgaaaat tcttttgttt ttcgttcctc acatgatcag caaatttctc
    90481 ctcggactat tcgccaaatt ttgagcaaaa ttacagtata taaaaacgta tcgccagaac
    90541 tatgcagaaa aacatatcgt tattatgcag aactatattt agatgatgct gacgcggtaa
    90601 attatttatg tggtaatcga tacctctcat cccattcttt tcaagatatc tgggaaaaga
    90661 tggttgattt ttcttatcac gaattagcgg cattcgttcg ggtttcttcc atataaaaca
    90721 aatgtatgat ctttttttca caataaacta tgttattata taaaggatta tgttacgatt
    90781 atcttgaatt tgtatattac ttaacaaaag ataatggagt gtgaatgatg gagaccataa
    90841 cgtattcccc tttgaactta tttacgaatt ttcaagaagc tgcagctaac ttttccgaga
    90901 ccccgattat ctttgatgag ccactttcag ctttcccaga attaggactt gaaacaactt
    90961 acaaaaaatg ctgcgaaagt gtgttgaaac gggcttatca attggctcat cttggagtga
    91021 aatccggaga caaagttatt atttataaga gttccgcttt tgacacatac cttctagctg
    91081 tttctgtgtc ttaccttggt gcagtgcctg tcatgacttc ttatcatcta ccaacaacaa
    91141 caatggaagt atttatcgat cgtttagaag accctttcat tttatttgat gatgagacaa
    91201 aaaagcgagt gagagaaatt tcaaatggaa caaaatcaaa acagattcc
//
LOCUS       DARPZF010000007        80485 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.007, whole genome shotgun sequence.
ACCESSION   DARPZF010000007 DARPZF010000000
VERSION     DARPZF010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 80485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80485
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.007"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            373..3180
                     /locus_tag="SLE65_000682"
     CDS             373..3180
                     /locus_tag="SLE65_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEI8447997.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            3371..3862
                     /locus_tag="SLE65_000683"
     CDS             3371..3862
                     /locus_tag="SLE65_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8447998.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            3965..4954
                     /gene="manX"
                     /locus_tag="SLE65_000684"
     CDS             3965..4954
                     /gene="manX"
                     /locus_tag="SLE65_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEI8447999.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            4987..5790
                     /locus_tag="SLE65_000685"
     CDS             4987..5790
                     /locus_tag="SLE65_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEI8448000.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            5811..6725
                     /locus_tag="SLE65_000686"
     CDS             5811..6725
                     /locus_tag="SLE65_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEI8448001.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            6808..7182
                     /locus_tag="SLE65_000687"
     CDS             6808..7182
                     /locus_tag="SLE65_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEI8448002.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            7321..7566
                     /locus_tag="SLE65_000688"
     CDS             7321..7566
                     /locus_tag="SLE65_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEI8448003.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            7738..8802
                     /locus_tag="SLE65_000689"
     CDS             7738..8802
                     /locus_tag="SLE65_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEI8448004.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            9048..9473
                     /locus_tag="SLE65_000690"
     CDS             9048..9473
                     /locus_tag="SLE65_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEI8448005.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            9466..9915
                     /gene="nusB"
                     /locus_tag="SLE65_000691"
     CDS             9466..9915
                     /gene="nusB"
                     /locus_tag="SLE65_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEI8448006.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            10012..10866
                     /locus_tag="SLE65_000692"
     CDS             10012..10866
                     /locus_tag="SLE65_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEI8448007.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            10867..12204
                     /locus_tag="SLE65_000693"
     CDS             10867..12204
                     /locus_tag="SLE65_000693"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEI8448008.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            12209..12433
                     /locus_tag="SLE65_000694"
     CDS             12209..12433
                     /locus_tag="SLE65_000694"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEI8448009.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            12435..13325
                     /locus_tag="SLE65_000695"
     CDS             12435..13325
                     /locus_tag="SLE65_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEI8448010.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            13334..14152
                     /locus_tag="SLE65_000696"
     CDS             13334..14152
                     /locus_tag="SLE65_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEI8448011.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            14259..14708
                     /locus_tag="SLE65_000697"
     CDS             14259..14708
                     /locus_tag="SLE65_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEI8448012.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            14726..16408
                     /gene="recN"
                     /locus_tag="SLE65_000698"
     CDS             14726..16408
                     /gene="recN"
                     /locus_tag="SLE65_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEI8448013.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(16463..16579)
                     /locus_tag="SLE65_000699"
     CDS             complement(16463..16579)
                     /locus_tag="SLE65_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEI8448014.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(16652..17608)
                     /locus_tag="SLE65_000700"
     CDS             complement(16652..17608)
                     /locus_tag="SLE65_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEI8448015.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            17779..18147
                     /locus_tag="SLE65_000701"
     CDS             17779..18147
                     /locus_tag="SLE65_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEI8448016.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            18318..18749
                     /gene="mraZ"
                     /locus_tag="SLE65_000702"
     CDS             18318..18749
                     /gene="mraZ"
                     /locus_tag="SLE65_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HEI8448017.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            18770..19729
                     /gene="rsmH"
                     /locus_tag="SLE65_000703"
     CDS             18770..19729
                     /gene="rsmH"
                     /locus_tag="SLE65_000703"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEI8448018.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            19734..20135
                     /gene="ftsL"
                     /locus_tag="SLE65_000704"
     CDS             19734..20135
                     /gene="ftsL"
                     /locus_tag="SLE65_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEI8448019.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            20136..22328
                     /locus_tag="SLE65_000705"
     CDS             20136..22328
                     /locus_tag="SLE65_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEI8448020.1"
                     /translation="MSLKNKIRRFMEKKNLNPINNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            22354..23316
                     /locus_tag="SLE65_000706"
     CDS             22354..23316
                     /locus_tag="SLE65_000706"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEI8448021.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            23330..24691
                     /locus_tag="SLE65_000707"
     CDS             23330..24691
                     /locus_tag="SLE65_000707"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEI8448022.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            24717..25805
                     /gene="murG"
                     /locus_tag="SLE65_000708"
     CDS             24717..25805
                     /gene="murG"
                     /locus_tag="SLE65_000708"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HEI8448023.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            25820..27040
                     /locus_tag="SLE65_000709"
     CDS             25820..27040
                     /locus_tag="SLE65_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HEI8448024.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            27196..28521
                     /gene="ftsA"
                     /locus_tag="SLE65_000710"
     CDS             27196..28521
                     /gene="ftsA"
                     /locus_tag="SLE65_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEI8448025.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            28544..29785
                     /gene="ftsZ"
                     /locus_tag="SLE65_000711"
     CDS             28544..29785
                     /gene="ftsZ"
                     /locus_tag="SLE65_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEI8448026.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            29802..30479
                     /locus_tag="SLE65_000712"
     CDS             29802..30479
                     /locus_tag="SLE65_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEI8448027.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            30493..31092
                     /locus_tag="SLE65_000713"
     CDS             30493..31092
                     /locus_tag="SLE65_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEI8448028.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            31107..31394
                     /locus_tag="SLE65_000714"
     CDS             31107..31394
                     /locus_tag="SLE65_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEI8448029.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            31443..32225
                     /locus_tag="SLE65_000715"
     CDS             31443..32225
                     /locus_tag="SLE65_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEI8448030.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            32246..32953
                     /locus_tag="SLE65_000716"
     CDS             32246..32953
                     /locus_tag="SLE65_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEI8448031.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            33215..36013
                     /gene="ileS"
                     /locus_tag="SLE65_000717"
     CDS             33215..36013
                     /gene="ileS"
                     /locus_tag="SLE65_000717"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEI8448032.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(36062..37588)
                     /locus_tag="SLE65_000718"
     CDS             complement(36062..37588)
                     /locus_tag="SLE65_000718"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEI8448033.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(37603..38250)
                     /locus_tag="SLE65_000719"
     CDS             complement(37603..38250)
                     /locus_tag="SLE65_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEI8448034.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(38434..38763)
                     /locus_tag="SLE65_000720"
     CDS             complement(38434..38763)
                     /locus_tag="SLE65_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HEI8448035.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            38940..39668
                     /gene="sfsA"
                     /locus_tag="SLE65_000721"
     CDS             38940..39668
                     /gene="sfsA"
                     /locus_tag="SLE65_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HEI8448036.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            39684..40697
                     /locus_tag="SLE65_000722"
     CDS             39684..40697
                     /locus_tag="SLE65_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEI8448037.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            40697..41974
                     /locus_tag="SLE65_000723"
     CDS             40697..41974
                     /locus_tag="SLE65_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEI8448038.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            42037..44739
                     /locus_tag="SLE65_000724"
     CDS             42037..44739
                     /locus_tag="SLE65_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEI8448039.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            44891..45208
                     /locus_tag="SLE65_000725"
     CDS             44891..45208
                     /locus_tag="SLE65_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8448040.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            45238..45558
                     /locus_tag="SLE65_000726"
     CDS             45238..45558
                     /locus_tag="SLE65_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEI8448041.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            45666..47126
                     /locus_tag="SLE65_000727"
     CDS             45666..47126
                     /locus_tag="SLE65_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8448042.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            47194..47415
                     /locus_tag="SLE65_000728"
     CDS             47194..47415
                     /locus_tag="SLE65_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448043.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            47446..47628
                     /locus_tag="SLE65_000729"
     CDS             47446..47628
                     /locus_tag="SLE65_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HEI8448044.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            47628..48041
                     /locus_tag="SLE65_000730"
     CDS             47628..48041
                     /locus_tag="SLE65_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEI8448045.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            48164..49345
                     /locus_tag="SLE65_000731"
     CDS             48164..49345
                     /locus_tag="SLE65_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8448046.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(49416..49580)
                     /locus_tag="SLE65_000732"
     CDS             complement(49416..49580)
                     /locus_tag="SLE65_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448047.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            49734..49807
                     /locus_tag="SLE65_000733"
     tRNA            49734..49807
                     /locus_tag="SLE65_000733"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:49768..49770,aa:Arg,seq:cct)
     gene            complement(49876..51015)
                     /locus_tag="SLE65_000734"
     CDS             complement(49876..51015)
                     /locus_tag="SLE65_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEI8448048.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(51314..51949)
                     /locus_tag="SLE65_000735"
     CDS             complement(51314..51949)
                     /locus_tag="SLE65_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448049.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINSASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(52062..52697)
                     /locus_tag="SLE65_000736"
     CDS             complement(52062..52697)
                     /locus_tag="SLE65_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HEI8448050.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(52731..53192)
                     /locus_tag="SLE65_000737"
     CDS             complement(52731..53192)
                     /locus_tag="SLE65_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HEI8448051.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(53322..53753)
                     /locus_tag="SLE65_000738"
     CDS             complement(53322..53753)
                     /locus_tag="SLE65_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEI8448052.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(53771..54091)
                     /locus_tag="SLE65_000739"
     CDS             complement(53771..54091)
                     /locus_tag="SLE65_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8448053.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            54390..55166
                     /locus_tag="SLE65_000740"
     CDS             54390..55166
                     /locus_tag="SLE65_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HEI8448054.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            55181..55384
                     /locus_tag="SLE65_000741"
     CDS             55181..55384
                     /locus_tag="SLE65_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8448055.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            55400..55738
                     /locus_tag="SLE65_000742"
     CDS             55400..55738
                     /locus_tag="SLE65_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HEI8448056.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            55725..55904
                     /locus_tag="SLE65_000743"
     CDS             55725..55904
                     /locus_tag="SLE65_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448057.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(55947..56417)
                     /locus_tag="SLE65_000744"
     CDS             complement(55947..56417)
                     /locus_tag="SLE65_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448058.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            56504..57202
                     /locus_tag="SLE65_000745"
     CDS             56504..57202
                     /locus_tag="SLE65_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HEI8448059.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            57380..57721
                     /locus_tag="SLE65_000746"
     CDS             57380..57721
                     /locus_tag="SLE65_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448060.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            57714..58385
                     /locus_tag="SLE65_000747"
     CDS             57714..58385
                     /locus_tag="SLE65_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HEI8448061.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            58391..59077
                     /locus_tag="SLE65_000748"
     CDS             58391..59077
                     /locus_tag="SLE65_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448062.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            59080..59829
                     /locus_tag="SLE65_000749"
     CDS             59080..59829
                     /locus_tag="SLE65_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8448063.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            59841..60110
                     /locus_tag="SLE65_000750"
     CDS             59841..60110
                     /locus_tag="SLE65_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448064.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            60116..60280
                     /locus_tag="SLE65_000751"
     CDS             60116..60280
                     /locus_tag="SLE65_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448065.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            60273..60572
                     /locus_tag="SLE65_000752"
     CDS             60273..60572
                     /locus_tag="SLE65_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448066.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            60572..60874
                     /locus_tag="SLE65_000753"
     CDS             60572..60874
                     /locus_tag="SLE65_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HEI8448067.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            60914..61279
                     /locus_tag="SLE65_000754"
     CDS             60914..61279
                     /locus_tag="SLE65_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448068.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            61769..61909
                     /locus_tag="SLE65_000755"
     CDS             61769..61909
                     /locus_tag="SLE65_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448069.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            61906..62094
                     /locus_tag="SLE65_000756"
     CDS             61906..62094
                     /locus_tag="SLE65_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448070.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKNLI"
     gene            62102..62296
                     /locus_tag="SLE65_000757"
     CDS             62102..62296
                     /locus_tag="SLE65_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448071.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(62329..62541)
                     /locus_tag="SLE65_000758"
     CDS             complement(62329..62541)
                     /locus_tag="SLE65_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448072.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            62666..62869
                     /locus_tag="SLE65_000759"
     CDS             62666..62869
                     /locus_tag="SLE65_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448073.1"
                     /translation="MVKVREQFKIVSDEDNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            62866..63138
                     /locus_tag="SLE65_000760"
     CDS             62866..63138
                     /locus_tag="SLE65_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HEI8448074.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            63139..63324
                     /locus_tag="SLE65_000761"
     CDS             63139..63324
                     /locus_tag="SLE65_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448075.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            63311..63658
                     /locus_tag="SLE65_000762"
     CDS             63311..63658
                     /locus_tag="SLE65_000762"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448076.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            63618..64094
                     /locus_tag="SLE65_000763"
     CDS             63618..64094
                     /locus_tag="SLE65_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEI8448077.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(64240..64968)
                     /locus_tag="SLE65_000764"
     CDS             complement(64240..64968)
                     /locus_tag="SLE65_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEI8448078.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            65016..65294
                     /locus_tag="SLE65_000765"
     CDS             65016..65294
                     /locus_tag="SLE65_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448079.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            65296..65682
                     /locus_tag="SLE65_000766"
     CDS             65296..65682
                     /locus_tag="SLE65_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448080.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            65679..66059
                     /locus_tag="SLE65_000767"
     CDS             65679..66059
                     /locus_tag="SLE65_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEI8448081.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            66171..66623
                     /locus_tag="SLE65_000768"
     CDS             66171..66623
                     /locus_tag="SLE65_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEI8448082.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            66620..68347
                     /locus_tag="SLE65_000769"
     CDS             66620..68347
                     /locus_tag="SLE65_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEI8448083.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            68411..69598
                     /locus_tag="SLE65_000770"
     CDS             68411..69598
                     /locus_tag="SLE65_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEI8448084.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            69570..70139
                     /locus_tag="SLE65_000771"
     CDS             69570..70139
                     /locus_tag="SLE65_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HEI8448085.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            70152..71516
                     /locus_tag="SLE65_000772"
     CDS             70152..71516
                     /locus_tag="SLE65_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEI8448086.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            71518..71799
                     /locus_tag="SLE65_000773"
     CDS             71518..71799
                     /locus_tag="SLE65_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HEI8448087.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETDQ"
     gene            71777..72103
                     /locus_tag="SLE65_000774"
     CDS             71777..72103
                     /locus_tag="SLE65_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEI8448088.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            72093..72431
                     /locus_tag="SLE65_000775"
     CDS             72093..72431
                     /locus_tag="SLE65_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448089.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            72421..72786
                     /locus_tag="SLE65_000776"
     CDS             72421..72786
                     /locus_tag="SLE65_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEI8448090.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            72793..73419
                     /locus_tag="SLE65_000777"
     CDS             72793..73419
                     /locus_tag="SLE65_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEI8448091.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            73419..73883
                     /locus_tag="SLE65_000778"
     CDS             73419..73883
                     /locus_tag="SLE65_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448092.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            74078..76387
                     /locus_tag="SLE65_000779"
     CDS             74078..76387
                     /locus_tag="SLE65_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEI8448093.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            76399..77103
                     /locus_tag="SLE65_000780"
     CDS             76399..77103
                     /locus_tag="SLE65_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEI8448094.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDDTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            77100..79859
                     /locus_tag="SLE65_000781"
     CDS             77100..79859
                     /locus_tag="SLE65_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEI8448095.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWRIYDILCNNGFTKQ
                     SACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLFN
                     AAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYER
                     PAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSG
                     YLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINW
                     ARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISSI
                     VIPPK"
     gene            79872..>80485
                     /locus_tag="SLE65_000782"
     CDS             79872..>80485
                     /locus_tag="SLE65_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HEI8448096.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETRIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLA"
BASE COUNT        27271 a        13204 c        16928 g        23082 t
ORIGIN      
        1 aaataaaagt tgtagtggag gctacgaagt ttactttgtc tttttacact taatattttt
       61 ttgccaattt ggaatcagga tgttttgata actatcgttt tcaattgatg gaagctatat
      121 tgtttgctat cagtgaaata attatatggt aaacagtgtt ctttttcttg tttccattat
      181 aaaaatcgta tcgggatttt tcgttctttt aaattgaaca tttctatcta tccgcgtgtt
      241 atcaacaaaa caaaatcagg taaatagttg acgaaacaga aataaataca tagtattatg
      301 ttttgaagcc taagtacaat agtctataga aaaggagcga taccattggc aaaacgcatt
      361 gaccgaattt atatgtatgt caaagaaaaa accgctcatt taacaaaggc agaatatgat
      421 caaggagtaa caacacagga aattgctgaa gtgttaggga ttcagcgaac aaatagcagt
      481 aaagatctga atcagctagt gcgcgaagga aaactgataa agacagacgg acgaccagta
      541 cgttacatat atcaaacact cgttacgcac gtaaagccag ttacaaaaca tgtagtcagt
      601 tacaaagaaa cgccggtctc tgaagaaaaa aatacactcc aaatagatac taaggatatc
      661 tttgcaaaaa tcattggagc taacggcagc atgaaaaatt cagtggaaca ggcaaaagct
      721 gcgattttgt atccgccaag aggattaaat tgtttgatta caggacctac cggatcagga
      781 aagacttatt ttgcacacgc gatgtatcat tttgcaaaag cgcatcatgt aatagatgag
      841 gaaacggaac tgattgtttt caattgtgct gattatgcca ataaccctga gcttttgatg
      901 agtcatttat ttgggtacgc aaaaggtgct tttacaggcg cagatgaaga aaaaatgggg
      961 attatcgatc aagcggatgg cggtatgctg tttttggatg agattcaccg gttgccgcct
     1021 gaaggtcaag aaatgatctt ttactttatg gatcatggaa cttacagtcg tcttggggaa
     1081 acaacgaaat cccatgaagc aaatgtacgg atcgtaggtg cgaccacaga agacccaggt
     1141 tcttctctat tagaaacttt tgttcggcgt atcccaatca atatcaaact tccggctttt
     1201 gaaaaacgtc ctgcaaatga gaaagtcgat ttagtaaaaa tcatgattgc ccacgaagca
     1261 aaccgcacgc agcgaaagat ttctttgaca gaagatgtag caaaagcatt gatcggcagt
     1321 gtgacctatg gaaatatagg acaattgaag tcaaatatcc agttagtatg tgcacgagga
     1381 tttctaaatc atatgcaatc acccgaaatc tcgatcacaa tcgatgattt gacagaaggg
     1441 attcgtagcg gattgattca attagcaagc aaccgcagtg caatggcaga gctttctaaa
     1501 atattggagc caaagataac tgtagcacca aatgatacga tcatgaaaat ccaatcggac
     1561 tcctatgagt taccttataa tctatatgat atcatcggag ataaagcagc tttactgaag
     1621 tcggatggtt tggatcaaga agcaatcaat catttcattt ctacagatat caacatccat
     1681 ctgaagtctt tctataaaga ccatggtttt tcttttaatg cagacagcaa attagcagaa
     1741 tttgtagatc cgaaaatcat agaagtgacc aatcagattt atgtaatggt caaaagatct
     1801 ttaccatatg agtttcagca aaactttatt tatgctatga gcttgcatat cagttctttt
     1861 ttgaaaaaaa tcaacttagg agaagaacgg catacgaatg ataacatccg tgagatggct
     1921 tttgattttc cagatgaata tgctgttgcg aaagaagtgc gtagttatat cgaaacgtat
     1981 tttcaagtgg agattccaga aagtgaagac tattacttga ccgttctact cgtctcgtta
     2041 cgggcaaatc aagcaagcgg cagaatcggt gtagtcgttg cagctcacgg aaacagcaca
     2101 gcaagcagta tggtccaagt tgtccaacag ttgttagatg cagagaacgt acgagcagta
     2161 gacatgcctt tggatatgga tccgaaaaca gcattggacc gaattgaacg caatgtacaa
     2221 gaagtagatg aaggaagcgg ggtcatactc ttagtagata tggggtccct tgcgtcgttt
     2281 aattcgcaaa ttcaaagaga cactggaatt ccagtacgta ctgttgatat ggtaacaact
     2341 tctctagttt tggaaactgt acgaaaggtc tcagtattag ggacagatct agatatgttg
     2401 catgaatcat tgaaaaattt tcgaggttac gcagaaatat cttctgtaga atctgttcag
     2461 gaagcaaaac ctattcataa gaaaaaagct gttttggcta tctgcgcatc tggcgaaggt
     2521 acagcacaaa gaatcaaaga attgatcgaa cgagcggtaa acaagcgtca agaaacagaa
     2581 ttagaagttc tagctttgtc gattgtggaa gtgaaagaag aactgccagt tatccaaaaa
     2641 gaatatcaga tcatagctac tactgggatt actgatttga atatccaagc cccatttatt
     2701 cctttagaac gttttattga tcaaaatatc gaagtcattt tggatcagtt gctgatggaa
     2761 tcagaattgg aggaaactga attcatctcc ctagatgaag agtcagctaa aaatacgtgt
     2821 gttgagttta tctctgataa cttcatcttt attaatggta gtaagttaat cgatccaatg
     2881 tggcaatttt ctacacaaat ctctcagacg acgggaatcg gcgatgaaga atatggattc
     2941 aaaatcaacc tagtgatgca cacagcagga atgatcgaac gtattattcg gaatgaacca
     3001 ttgactgtgg aagaaaacga attgacaaat acaacgaatg atcctcttta tagccaattg
     3061 gcagcctcag ttgttctgtt ggaagatcag ataaaagtaa aagtgccgat agaagaaatg
     3121 tattatctgc tacgtctagt ccataatcag ttagataaaa aagaatacac tgtgccatga
     3181 atacacaaaa acgatacact tttatagtgt atcgtttttg tgtattggtt aagaatcctt
     3241 taaattcaat tagtgtatcg taaaaaagtt ggcacgcttt ttgcttatag tagtgtgtgc
     3301 taggaggtgg ttgttcacac agaaatgata ggggtttctg tgaagtagtg aggaagaagg
     3361 agttttgcag atggatattc gattggcacg tatagatgat cgtttaatcc acgggcaagt
     3421 cgcaacagtt tggtcgaagc aaacaggtgt tgaacgtatc attgtgatca gcgatgtagt
     3481 cgctcaagat aaattgagaa agtttctact aaaagaagct gcaccgccgg ggatcacagc
     3541 aaatgtaata accgtgcaga aaatgattca aatctatcat agtggattat tatcacgagc
     3601 aaaagtgatg cttttattca ccaatcccca agatgttgaa gcggttgtcc gctgcggtgt
     3661 acagttgaag tcgttgaata tcggcggtat gagttttact gaaggcaaat caatgattac
     3721 caattttgtt tcagtaaatc aacaagatat tgattccttt cgttacttga acagtcaaga
     3781 agtggagtta gagattcgaa aagtacctgc tgacaggaaa atccttttga tggaactact
     3841 agcgaaaatc aaaaaggtgt agcaagaatg gttgttggaa aaggtcaaat aattctgttg
     3901 taatggttag caattattaa tatttttgaa tttgttacaa caaaagtaaa taggaggtat
     3961 aaatatggta gggattatcc tagcaagtca tggacaattt gctgaaggaa tcttacaatc
     4021 cggttcaatg atctttggcg aacaagaaaa cgtcaaagcc gtgattttga aaccaagtga
     4081 aggtccagat gacttgagag ccaaattgga agaagcggtt gcttcttttg ataatcaaga
     4141 cgaagtgtta ttcttagttg atttatgggg cggaacaccg ttcaatcaat caaacacatt
     4201 attcgaagag cacaaagata aatgggcaat cgtcagcggt ttgaatttac caatgttgat
     4261 tgaagcctac gcatcacgct tttcaatgga atctgctcat gaaattgcag cacacatcat
     4321 tgaaacagca aaagacggtg taaaagtaaa accggaagaa ttagaaccgg cagaagcacc
     4381 gaaagcagca gttgaagacg cacaacctaa aggagcactt ccagaaggaa ctgtggtcgg
     4441 agacggaaaa atcaaatatg tattagcacg tgttgactca cgtctgttac atggacaagt
     4501 tgcgacagct tggacaaaag cagtgcaacc aaaccgtatt atcgttgttt cagatgcagt
     4561 atcaaaggat gatctgcgta agagactaat cgaacaagct gctcctccag gtgtaaaagc
     4621 aaatgttatt cctattagca aaatgatcga agtagcaaaa gaccctcgtt ttggaaatac
     4681 caaagcattg cttttatttg aaaatcctga agacgtattg acagctgttg aaggtggcgt
     4741 agacatcaaa gaattaaatg ttgggtcaat ggcgcattcg gtcggtaaag tcgttgtaag
     4801 taaagtattg tctatgggac aagaagacgt tgaagcgttt gagaagcttg aacaaaaagg
     4861 tgtgaaattc gatgtacgta aagtacctaa tgattcacgc gataacatgg atgatatttt
     4921 gaaaaaagca aaagctgaat tagcaaaagc gtaataaata atattaaaat ttataggagg
     4981 cttatcatgt ctattatttc aataatttta gtcgtattag ttgcctttct agctggtatg
     5041 gaaggtattc ttgatgaatt tcaatttcat caaccactag tggcatgtac attgatcggt
     5101 ttagttaccg gtaacctcga agctggtatc gtacttggcg gtacgcttca gatgatcgct
     5161 ttaggttggg caaatatcgg tgccgctgta gcaccagatg ctgcattagc atcagtagca
     5221 tcagcaatta ttttagtttt aggtggacaa ggtgttaaag gtgttccttc tgcgatcgcg
     5281 attgccgttc ctttggctgt tgcagggttg ttcttaacaa tgatcgtacg tacaatcgct
     5341 gttccaatcg ttcatttgat ggatgcggct gctgaagaag gaaacatccg taaggttgaa
     5401 atgtggcaca tcattgctgt atgtttacaa ggggttcgta tcgcggtccc agcagcagcg
     5461 ttgctattta tcccagcaca aactgtgcaa tcattccttg aatcaatgcc agcatggtta
     5521 acagatggta tggctatcgg tgggggaatg gtcgtagctg taggttacgc tttggtaatc
     5581 aacatgatgg ctacaaaaga agtatggcca ttcttcgtta ttggtttcgt tgtagctgca
     5641 atttctcaat taacattgat tgctctaggt gctttaggtg ttgcattagc tcttatttac
     5701 ttgaaccttt ctaaaatggg tggttcatca aataatggag gcggaagcaa ctctggtgac
     5761 cctttaggcg acattttgaa tgactattaa tcttgaagga ggaaaataaa atggcagaag
     5821 aaaaaatcaa attatcaaaa aaagatcgtt tagctgttgc gtggcgctct accttcattc
     5881 aaggttcatg gaactacgaa cgtatgcaaa acggtggctg ggcattttct atgattccag
     5941 caatcaaaaa attatacaaa acaaaagaag aacgttctgc agcattaaaa cgtcacttgg
     6001 aattctttaa tacacaccca tacattgctt ctccaatttt aggggttaca ttggctctgg
     6061 aagaagaacg tgcgaatggc gcgcctgttg atgatgtagc gattcaaggg gttaaagtag
     6121 gtatgatggg tcctttagct ggtgttggtg acccagtgtt ctggtttaca gtacgtccaa
     6181 tgctaggtgc actaggtgct tcattagcta tgggaggaaa tatccttgga ccaatcatct
     6241 tcttcttagg ttggaacatt attcgttggg cattcatgtg gtatacacaa gaatttggct
     6301 acaaagctgg ttctaaaatt actgatgacc tttctggcgg attgttacaa gacgtaacaa
     6361 aaggtgcttc aattttaggg atgttcgtat tagctgccct tgtacaaaga tgggtatcaa
     6421 tcaaattctt accagttgta tcaactgtaa aattagataa aggtgcttac atcgaatggg
     6481 ataaattgcc ttcaggtggt gaaggaatca agagtgcatt tgaacaagtt aataatggct
     6541 tagccctttc tcctgaaaag gtaacaacat tacaagacaa cttagaccaa ttgattcctg
     6601 gtttagctgc attaggatta acattgttat gtatgtggtt gcttaagaaa aaggtttctc
     6661 caatcgttat catccttggt ttattcgtag tcggtgttgt tggacacgtc atcggacttt
     6721 tataatccat aaaaatatag ctcgggcgtt gtcccgagct ttttttatat agtatactgt
     6781 tcataaacaa atatctggag ggagaaaatg gttcaatcaa tcaatacaaa agtagacttg
     6841 gtaattgatg ctacttcgtt tacgggtctg acagattacg ggcaaatcat gataggtgat
     6901 aatggttttg agttttacca tgcgcgagat agacgcaaat atatccaaat tccatgggaa
     6961 gaagtggatt atgtactagc atcagtcatg ctaaagggaa aatggattcc tcgatatgcc
     7021 attcaaacga aaaaaaatgg tacatacaca ttttcttcca aagaacctaa aaaagtgctt
     7081 cgtgcgatca gagaatatgt agatgaagat agaatggtac aatcattgag tttctttgat
     7141 gtagtgaaac gtggtattcg tagtatgttt aaacgcaagt aaaaaataaa gaaaacttct
     7201 aagaggaggt tttctttatt tttttacttt gcagaagaaa atatgaaata gcaaaaccaa
     7261 ttatttgtcc cctttaaatc ccatatgcta aaattgatta gcaaagaagg aggttatatt
     7321 atgagttggt tatggacatt gattgttgga gccgtgatcg gagcaattgc aggtgcgatc
     7381 accagtaaag gaaattcgat gggctgtgta acgaatatca ttgctggact agtcggttca
     7441 agtattggac aagcgatttt cggcgaatgg ggaccaaaag ctgcaggtat ggcacttatt
     7501 ccatctattt taggcgcagt gattttggta gcagttgtct catttttctt tggaaaacga
     7561 tcataagttt ttacaaaata gtaaactaaa aggagttgca gcgagactgt gactcctttt
     7621 tggctttatt tatttaaaat aaaaagaagt tttccggaaa tttttattta actgtcgtgt
     7681 acgaagaaaa gtttgctata atggaaaaaa gcgtgcaaag aaagagggag tttcattatg
     7741 atgctacgtg tagaaaaatt gcgcaaaaaa atgcaagaag aaaatttgga ttcatttttg
     7801 gttaccagtc cgtacaatct tcgttactta acgaacttta caggtacgac aggattagct
     7861 gttattactt tggaaaaagc attttttatt actgattttc gttataccga gcaggcggca
     7921 gcgcaggctc aagggtttga aattattaaa aatgtcggac ctatttttga tgaggtagca
     7981 aacttagtac gcaaagaaga actgcactca ttagcttttg aggaaacaac agtctcattt
     8041 ttagaatatt cggttttaga agaaatcatc gatgcggaat tagtacctgt ttcacagatg
     8101 atcgaagaac tcagagaagt gaaagatgaa gaagaaatcg ctattatcga aaaagcatgt
     8161 catattgcgg atatggcata tgatcacatc ctgaaaatga tccaaccggg catgactgag
     8221 attgaagtcg caaatcaact agacttttat atgcgttctc ttggcgcttc aggtgtttct
     8281 tttgatacga tcgttgctag cggattgcgt tcggctatgc cgcatggtgt agcaagcaaa
     8341 aaaatcatcg aacaaggtga cttgatcaca ttggactttg gttgctatta cgaagggtac
     8401 gtttccgata tgacacgtac attcgctatt ggtgatcctg gggaaaaatt aaaagaaatt
     8461 tatcaaatag tcttagatgc tcaattagca gttattgatg ctgcaaaacc aggaatgact
     8521 ggtgtccaat tagatgcagt tgctagagat tatatttcaa aacatggtta cggggaagca
     8581 tttggacatt ctacaggaca tgggatcggt ttagagatcc acgaaggacc aaacgtttct
     8641 tctcgtgcag aaaagcaatt tgtaccagga aatgtgatca ctgatgaacc agggatctac
     8701 ttaccaggaa tcggtggagt acgtattgag gatgacttgt tgatcacaga agatggaaat
     8761 cgtgtgttga ctcgttcacc aaaagaattg atcatcttat agtttcatca atagaagaag
     8821 taagcgtaaa aatcagtgtt cacagacttt gttatagaaa atcactcgat ttaatgatac
     8881 actatagaag aacttttaag ctgtaagaga taataaagtt gggtgttttc tccaattcat
     8941 agcagtttgc agctgatcgg cggcagtttt cttaccacgt gatcactatg ccgcatcata
     9001 gagaattcgg atgtatctcg tgcttaggca aagggaggaa taaataaatg gcagatgaaa
     9061 aaaatttgat tttaaacgca aaccaagatt taggagagat cgtgatcgct cctgaagtca
     9121 tcgaagtaat tatcgggatt gcagcttcta aagtagaagg cgtatacgga atgcgcggaa
     9181 cttttgccag caatgtcact gaattattag gacgtgcagc tcacggaaaa ggtgtttact
     9241 tagcaaacga ggaagatggc ttgaaagtag atctttactg ttatctagaa tatggtgttt
     9301 cagttcctaa agtagcaatg gaaatgcagg aacgggtcag ccagcaagtc cttttcatga
     9361 cggatatcga tttatctgaa gtcaatatcc atgtagtagc tgttgttcct gaaaaattag
     9421 aacaaccaac aatcgaagaa ctttttgaag acgaagagga agagaatgaa taaagaatta
     9481 tcaagacacg agattcggga aatggcattg caggctttat ttccattaga cttcaatgca
     9541 gacctaacaa aagaagatgc gattttcaac gcaatcgaat tagaccaccg cgacatgatc
     9601 aacgaagatg aatcagagtt tgttcctgtt tatcttgata cgctagttgg cggtgtctgt
     9661 gcaaaaaaag atgaattgga taaagtgatt gaaaaacatt taaaaaacaa ttggcacatc
     9721 aatcggatct caaaaatgga tttggtgatc ttgcgtatcg cgatttttga aatgacttat
     9781 gtgacagatg taccagcggc tgttgcttta aatgaagcaa tcgagttggc aaaaacattt
     9841 agtgatgacc gttcacgtaa attcgtcaac ggtgttttat ccaatgtatt gaaagaatta
     9901 gaagctgggg cgtaagtcct agcttttttc tatgaatcat cataaacctg ttataaatcg
     9961 ggaaaattct atggtagaat gaaaacacaa aaaatatctg ggagtggtta gatggcagaa
    10021 ttgattaacg gaaaagaatt agctgaaaaa atgcaggcag agattgctga aaaaatccaa
    10081 aaattgaaag ataatggtat ccatcccgga ttagtcgttt tattggtagg ggaaaatcca
    10141 gccagccaaa tctatgtaag aaataaagaa cgtgtagcaa aagaaatcgg aatccattca
    10201 ttggtagagc gttatcctga gacgatttct gaagacgaac tacttgcaga aattgaaaaa
    10261 tacaatcaag atcctagttt tcatggtata ttggtccaat taccattgcc aaagcatata
    10321 gatgaagaaa agatcctgtt agctatccgc cctgaaaaag acgtagacgg ttttcatccg
    10381 atgaatttag gcagactcct tgcgggtaaa ccggacaaga ttccttgtac tccatacggc
    10441 atcatgaaaa tgtttgaagc ttattctatc gatccggcgg gtaaacgagc agtagttatc
    10501 ggacgaagca atatcgtcgg taaaccgatg gctcagctac tcttgatggc agatgcaact
    10561 gttactgttg ctcattctaa aaccgaaaat ctggctgaac tggcacaaga agcagatatt
    10621 ttagtcgtag caataggacg tggacatttt gtcacaaaag aattcgtaaa accaggtgct
    10681 gtagtgatag atgtagggat gaatcgtgat gctaacggta agctgatcgg tgatgtgaaa
    10741 tttgatgaag tggagcctat tgcaggctgg atcactcctg tgccaaaggg tgtagggcca
    10801 atgactatca cgatgctgat gtatcaaacc gtaaaatctg ccgaagcttt tggagcaggt
    10861 gaatagatgg cacaagaata tttaactgtc actacattaa cgaagtattt gaaaagaaaa
    10921 tttgatgccg atccttattt agaacgcgta tatttaacag gcgaaatatc gaatttccgt
    10981 ttacgtgcca atgcccatca atatttcagc ttaaaagatg accatgcaaa aatatctgct
    11041 attatgttca aaggagcatt ccaaaaatta cgattccagc caaaagaagg aatgaaagtc
    11101 cttgtcgttg ggcgtatttc attatatgaa gcgggaggtt cttatcaaat ctatgtagag
    11161 cacatggagc ctgatggaat aggtgcttta tatcaagaat tggaagaacg aaaagaaaag
    11221 ctgatgaagg aaggcctttt tcaagggcct aaaaaaatgc tgccacgttt cccaaagcga
    11281 atcgcggtcc ttaccagtcc aagcggagcg gttatccgcg atatcatcac gacggtgaaa
    11341 agaagatatc caattgtcca attggttttg ttcccaacag ttgtacaagg aaaccaagca
    11401 gcggacaatg ttgtcaggaa tatccagaga gtagaagaga tgggcaattt cgatacaatg
    11461 atcatcggtc gtgggggtgg ttcgattgag gatttatggc cgtttaatga agagcgggtt
    11521 gctcgggcga tttatcaagc taatacgccg gtgatttcat ctgtaggaca tgaaacagat
    11581 accacgatcg ctgatttagt agcagatgtt cgggctgcca ctccaacagc agctgcagaa
    11641 ttagctgttc ctgttttgtc agaagagttg atgcgcattc aagaacggca agctagattg
    11701 cagcaggcgt ttgtacgcca gatccagcgc aaacaagaac ggttcgagcg tgctcgacgt
    11761 tcctatgtat ttcggcagcc tgaaagattg tatgaaggtc agaccatcaa attagaccag
    11821 ttgaaacagc gattatatca agctacacag caaatttatc atgcgaaaga aaaacaaacg
    11881 atcgcattaa gccaccaatt ggaacaagtg gctccgcttt atcgagttaa agcagctcgc
    11941 caagaaactg cttatctaga aaaacgctta gaagagaaaa tccaacaata tatgaaacaa
    12001 cagcagcagc gttttgctca agctgttcaa tctcttgatt tgttgagtcc attgaaaatc
    12061 atgggaagag gctacagcta tacgacgtta aatgatcaag tagtaaaaag tgtcaccgag
    12121 attcatcaag gggatttgct gacgatccat tatcaagatg gaatcgttaa aggacaagta
    12181 caagagatag acaaaggaga ataaaaatat ggaaaatcca acttttgaag agtcactgca
    12241 agaattagaa aaaattgtca tgcagttaga acaaggagac gttccattag aatcagctct
    12301 agattcgttt aaacgaggaa tggaattaag caaacattgc caagatacat tagctaaagc
    12361 agaagagacc ttgacgaaaa tgatgacaga atcaaatgaa gaagttgatt ttgacggaaa
    12421 cgaggaaagc tgagatgaga ttaactgact tttcagctat tcatctacct gctgtagaaa
    12481 aagaaatctt gtctttttta gatgagcata caacggatag aggactctat gatgcgatga
    12541 gttattcagt gaaagcaggc gggaaaagaa tacgtccctt attactttta acggccgttg
    12601 cttcctttga tgagcctatt gatgttcccg tctatcaagt agcagctgct ttagaaatgg
    12661 tgcatacgta ttccttgatc cacgatgatt tgcctgcgat ggacaatgat gatcttcgta
    12721 gaggaaaacc taccaatcat aaagtattcg gcgaagcatt agctatattg gccggagatg
    12781 gtttgcttac aggagcattc cagctaatca gtatggcaca cttaggtaat tctcctaagc
    12841 ttctgctgct tcagcaatta gctgtttgtg cgggatcaca aggtatggtt gctgggcaag
    12901 ctgcagatat cgagggcgaa tcgaaaaagc tttctttaga agaattagca tttattcatg
    12961 aaagaaagac agggcatttg attcgttatg ccttgctggc tggtggcata ttagcgaagc
    13021 aacctgaaga aatcttattg ctacttcaac gattagccga acatttaggt ttagcttttc
    13081 agataagaga tgatctactc gatgtgattg gtacaacgaa aacattaggg aaaacagctg
    13141 gtaaagatga acgtatggaa aaaaatactt acccgcgttt attaggccta gaaaagacac
    13201 gtgaggcgtt ggagattgag ctgttatccg ccaacaagat catagacaaa ttagaagagg
    13261 acgttttttc ttttgatggc gggctgatgc gccagatgat caagcaattt gatgtggaga
    13321 aatgagggaa agaatggaaa aagaacgcgt agatgtatta gcggtcaaac aaggattatt
    13381 tgaaacaaga gaacaagcca aacgttcagt gatggctggt ttgatttaca acgaaaaaaa
    13441 cgagcggttt gataaaccgg gagaaaaaat tccagtgagt agtgaattaa gagtcaaagg
    13501 taaaaaactt ccttatgttt ctcgaggggg attaaaatta gaaaaagcac tcaaagcatt
    13561 tgatctatct gttgaaggaa aaacattgtt agatattggt gcatccactg gcggatttac
    13621 tgatgcagct ttgcaaaatg gcgcaaaaat gagttatgct ttagacgttg gctacaatca
    13681 gctagcttgg aaaataagac aagatcctag agtcgtcgta atggaaagag tgaattttcg
    13741 ttatgcaaaa cccgaagact ttaccttagg aattccagaa gttgctgtta tcgatgtttc
    13801 ttttatttca ctaaaactga tgctgcctcc attacatgct attttaaaag aagagggaga
    13861 agtgattgct ttaatcaaac cccaattcga agcaggcaga gaagctgtag ggaaaaacgg
    13921 aattgttcgt gaccctcaga cccatcaaaa agttttagaa gacattttgt catttgcggc
    13981 acaaggtgga tatgatgtgc tggaattaag ttattctccg atcacggggg gagaaggaaa
    14041 tatcgagttc ttggctcact tgaggaaagt acccgaaagc ggaacaatca attcagctat
    14101 taatatggca gaagtggttt caaatgcaca cgaacagttt gaccataaat aaattgtaac
    14161 tgtgaaaatc aagtgagaag tatgcggatt cttctttatt ataccaagga aataagctat
    14221 cattgattaa gaagaatatg ctaaggagcg aagacgtaat gagaaaaaaa gatcggcatc
    14281 gtttgattac tcgattgttg agtgagcaag atatccgaaa gcaggaagaa tttgttgaaa
    14341 tcctgaaaag caaaggaata tctgttactc aagctacgat ttccagagat ataaaggaac
    14401 tgaaactgat caaggtaccg gcttcagatg gcggctaccg ttatagcata ccagctgaaa
    14461 caaacgaaga tgtaaatact aaattggaaa aactattaaa agacgctttc gtggcagttg
    14521 accaaatgga aaaatttgtt attttgaaaa cattgccggg aaatgcttcg gcagcagcaa
    14581 atttgattga taaacgttac aagaaagaat tattttcgat tatcaatgat gacgataatg
    14641 ttttgatgat tacacgaact gaagaccagg cagttttatt gaagaaagac ttcctgcatt
    14701 acctttaagt tgaggagcga atgtgatgct acaagaaatc agtattacta actttgcgat
    14761 tattccggaa ttgcggcttt cttttcacga aggaatgacc gcgctgaccg gagagactgg
    14821 tgcgggtaaa tccattatta tcgatgcttt aggtctgtta gcaggaggaa gaggttcaag
    14881 cgattatata cgtcaaggag cagaaaaatg tgtgcttgaa gggttgtttg aactaccaaa
    14941 acaagaagga ttctctgaac tgatggttga attagggatc gaaacagatg aggacaatct
    15001 gattgttcga cgggatatgt ccttaactgg aaaaaatgtt tgtcgagtga atggtcatat
    15061 tatcacatta gctaatctga gaagaatcgg cagttattta gtagatatcc aaggacaaaa
    15121 cgaacatcag gaactgctcc agcctgaatc acatcttgct ttattggatc gttttggaga
    15181 tgtagctttc caacagaaga aaaagagtta tcagcaagaa tatatctctt atcgtgagct
    15241 ggaaaaaagg gtacgaaaag tgcagcaaaa tgaaaaatcc tatgttcaga gaatagatat
    15301 gctccatttc cagcaagaag aaatagctgc tgctgatttg caagtcggag aagaagagaa
    15361 attaaaagaa gaaagagaaa aacttagcaa ttatcaaaaa attgctgatg gattagctgc
    15421 aggttacgga gcactgacga ataatgaaca aaacagtgta gatggtgttg gcttggccgt
    15481 ttcagaactg caagggatcg cccatctaga tgtggagtat gaagcaattt atgaaaatat
    15541 ccaaagtgct tactatttgc tgcaagatgc aatcggcgat atgagtcgtc agattgattt
    15601 attggagtta gatgagagtc gtttagaaga agttacgcaa cgtttagaat taatccgaca
    15661 gttgaaacgt aaatacggcg aatccattga gtcaatattg gcttactatg acgaaatcac
    15721 cgaagagcta gcttcttctg atttttcaga aggtcaattg gacaaaatga aagaggaact
    15781 agagcaaaaa gagcttctac ttcagcaaca agccgcagat cttcatgaag cgcgtaaaaa
    15841 aatcgcaaaa gaattggaaa aatccattct gcatgaattg aaaagtctgt atatggaaaa
    15901 cactgagttt gaggtacgtt tcttaaaaga agaaaataga caattgaatc atgatggatt
    15961 tgaccaaatc gaattttaca ttacgaccaa tccaggagag ccactgaagc ctttggtgaa
    16021 agtcgcttct ggtggcgaac tgtctcggat gttgcttgct ttgaaaacta ttttttcttc
    16081 tgagcaaggt gtgacaagta ttatttttga tgaagtggat acaggtgtga gcggaagagt
    16141 tgcacaggcc atcgcagata aaatttctca aatatcgaaa tactctcaag ttttgtgcat
    16201 cactcatctg cctcaagttg ctgcagtcgc cgactatcaa tattatattg tgaaagcagt
    16261 gattgatgga cgtacgcaaa cttctgtttc agagttgaaa acaaaagaaa gagaagaaga
    16321 aattgcacgt atgctggctg gaagtgagat tacaaaactc acactcgaac atgcaaaaga
    16381 actattgaaa ctcgcaaaaa ggacctgagc cacctcgcag tggttcaggt ccttttcagc
    16441 agctgatagc tatattttat ttttacatga cactcattac agcagtcaat acaacagatc
    16501 caatcgttaa aatcagcatt gtccaaatga caaattttgt tactttagca aaagtacttg
    16561 tttgtttttt ttcacgcatt gttttcaacc tcgtcattaa ttagttgatt caagtgtaca
    16621 atcttttttc catttccaca agagggcttt tttataaaaa cttccctttt tttaaataat
    16681 aggtagttac gatacaaata aataatgtta atagaactag ccatataaag gcatcatccc
    16741 tttcagcaat aggtaactta atgttcattc catagatact gccgacgatt gtcggtatag
    16801 ttaaaataat cgttaaagaa gttaaaattt tcataatatt attcagatta ttcgatacga
    16861 ttgctgaaaa agtctgattc atttgttcta ctagttttaa ttgaatgcga gaagtagtca
    16921 ttgcctgctc tgtttccacc aatacatcac gtaaatgatt tttcaaagca tgattttctt
    16981 ggaaaagttt attttgcgct agttctttca atgcatctaa attagcagaa gtcgcttctc
    17041 tgaaataaac gaggcttttt tggatatcca tgatttgata aagttgtttg ttttcagtgg
    17101 atacttgaag tttggcttcc aaagtatcgc attgagattg aagcgtagct aaataactgt
    17161 tgtaagagag tgtgacctgc caaatgaatt gaaagaagat attgagatta ggcgaaatat
    17221 cactttttgg aaaggtctgg ctaaagactt tctttaaaaa cagtggttca tgattcgtaa
    17281 ttgtgataag cttctttttg ggcgtcaaaa taatagagag cgggtatgta tccacttgaa
    17341 aataaccgct aggacttgtt ttagcaaaag gatattgtaa caataataac gctggctttg
    17401 tcaactttga ttgattgaat tcttctgtac gggaattttc tgcatcgtcc aatatggaag
    17461 tgatgtaatc tgacggaatt tcaaattgat gtgtcagctg atgaatctct tcttgattag
    17521 gacgttctac acaataccag atcgtttggt cagtttcctt tccggtatta cgcagtttct
    17581 cattatctaa tgtaaaatat ttgatcatga ttttcctcct gttgcctgtt tcttttatta
    17641 taacggatag ggaattggaa tacatggaat gtgtttgtaa gatatagaat ataactgcat
    17701 aaatttaaat aaaatgaaac agttgtgtaa agtatataca gtatacttga agcaacgata
    17761 aaaaaggagt ttacgttcat gggcacattc acaccactta tcttgttttg gtatatttac
    17821 ccggtaatcg ttttgtttgg ttgccaattt cttgtaaaat tattttcgtt aaatcgtcgt
    17881 tttaaaataa aagcccctga tttggcgatt ccttttttgt ggggcggtat gcatgcattg
    17941 tctagaaata cagggacaat ttctatctta ccgtttttct ttatttctgt tttgctaatg
    18001 ggaatttgta ttgctgtttt ccaagcatat tattatgaag aaattattta tccgcgttat
    18061 ttcaagatga cttggcgttt ggtttttctg ttgacaatcg tcttgtacgc tgtcttgatc
    18121 attgtgaaca tactttctta cctatgaaaa aaatagaaaa gctgtaaaaa gtcttttaaa
    18181 aggctttttg cagcttgatt tttaaaaaaa tgtttatgaa taaaaaaagt tgttcccgga
    18241 tttcccagaa aaggtggtag aaagtggggg attgtggtag actaatttta gttagtggag
    18301 gaatgggggg gctttcaatg ttgatgggtg aattccaaca taatattgat gcaaaaggac
    18361 gtttaatcgt gccctcaaaa cttcgtgaag aacttggcga aaagtttgtt ctgacacgcg
    18421 gattggatgg ctgtcttttc ggctatccga tgagcgaatg ggaaaatctg gaagctaaac
    18481 tgaacgaaat gccgttggct aaaaaagacg cacgtacttt tgtgcgattc ttctattcgg
    18541 ctgccactga atgcgaactt gataaacaag gacgaatcaa tatacccagc acgttaagaa
    18601 attatgcagc tttgacaaaa ggttgcgtag tcatcggtgt atctaaccga attgaaattt
    18661 gggatgagac acgatggcaa gatttttctg cagcagcaga agagaacttt gacgaaattg
    18721 ctgaaagtat gattgatttc ggactataag aataggaaga ggctgactaa tgactgaaac
    18781 atttcaacac tatacagtca tgttgaaaga aacggtagat ggattgaaca tcaaaccgga
    18841 tggcgtttat gtagactgta cactcggcgg tgccggacat agtgaatatt tattaagcca
    18901 actaagttct aaagggcatc tgtatgcgtt tgaccaagat caaaaagcaa tcgatcacgc
    18961 caagctgcgt ttagcttctt atgtcgaaca aggtatggtc acatttatca aagcgaactt
    19021 cagagaatta gaagaacgct tgagtgagca tgtagataag gtagacggca ttttgtatga
    19081 tctaggggtt tcctctcctc agctagatga agcagaacgt ggatttagtt atcatcaaga
    19141 tgcaccgttg gatatgcgca tggatcagtc agctccttta tccgcttatc acgtaattaa
    19201 tgaatattcc taccatgaat tagtaaagat tttcttccgc tatggcgagg agaaattttc
    19261 caaacaaatt gctcgtgaaa tcgaacgagt acgaaaaaca aaaccaatcc aaacaactgg
    19321 tgagcttgtc gaaatcatta aacaagtcat cccagctccc gcaagaagaa aaggcgggca
    19381 tcctgcaaaa agaatttttc aagctgtgcg gattgcagta aatgacgaac tcggtgccga
    19441 agaggcctct ttagaacagg caatccggtt attgaaagtc aatggaagaa tcagcgtaat
    19501 cacattccat tcattggaag acagaattgt caaaagtatg tttaaagaat atagtacggt
    19561 acaagatcta ccaccgggac ttcctgtcat acctgacgaa ttccaaccag aactgaaagt
    19621 cattactcgt aaaccaatcc ttccttcaga ggaagagcta acagaaaaca atcgatcacg
    19681 cagtgcaaag ttacgtattg cagaaaaaat aagaatgaaa gaggagtaga atgatggcag
    19741 aattaaagaa aatgcaagat tacgaatatg atttacctga attggtggat cagccggaac
    19801 aacaaatgcc tgattcttct tcgaatcaag aaatcattct tccacaatca ccggcaaaac
    19861 gattaaagca gatttctgct ttggaaaaaa ttgctgtggc aagcgtggcg attgctattg
    19921 ttgctttatg tgttttaaca gttatgctgc gcacaaatat cagcggagct gaaaaagaaa
    19981 tcacgtcaat acaaacagaa atcaatgata aaaagcaaga aaaaacgagt ttagaacaag
    20041 aaaaaaacga actttctcgt actgaacgga ttaaacaaat cgcagaagaa aaaggattgt
    20101 ctattaatga cgacaattta aggaaagtga agtaaatgag tcttaaaaat aaaattcggc
    20161 ggtttatgga aaagaaaaat ctaaatccga taaacaatcg caaaaaagta ggtatcattt
    20221 tatttgctac gagtattgga ttgttctttt tatttgccgt ccgtttctcg tatatcgtta
    20281 ttggaggtca tgttgctggt acctcattag ctgaaaaaac aaaacagttg taccaaggaa
    20341 gtgaagtagt aaaagcaaaa agaggaacga tttatgatcg taacggtgtg gcgctcgcag
    20401 aagatgcctc ctcttattca attaaagcga tactctcaaa aacatatacc tctggggata
    20461 aaaaactgta tgttgaagaa aagaattttg ataaaatagc agaaatcctg cataagaatc
    20521 tttctataga caaaaaagat gcactgaata ttttagagga cggcgcaaaa aaagagctgt
    20581 atcaagttga atttggtagc tatgggaaaa atatctccca agaaaccaag caaaacatcg
    20641 aagcggacat gaaaaaagaa ggtgtcgctg gtctttattt tgtcgaccat caggctcgga
    20701 tgtatccaaa tggcgtcttt tcttctcatt ttattggata cgcagttcca gacaaagatg
    20761 agaatggctt agttggtaaa ctaggtttgg agtctgctta caatgatatc ttgagcggta
    20821 aagatggtaa gattatttat caaaaagata attttcaaaa tcctctgcca ggtacagtgg
    20881 cagaagaaga aaaagctgtc gacggacaag atatctacac gactttagac agcagactac
    20941 aaagttattt agaaacactg atggatcaag taaatgaaga atatcagcca gaagaattga
    21001 cagcagtcct gatgaaagca aaaaccggag aaatcttggc aatgggacaa cgacctactt
    21061 tcaatcctga aacaatggaa ggattgactg gaaaagatgc tatctggcgt aatttcttgg
    21121 tacaagatag ttatgaacca ggatcaacca tgaaagtttt cactactgca gctgctatcg
    21181 aagaaggaga attcaacgag aatgaaacct tccaatctgg aaaaatccaa gtagaagatg
    21241 ctacgatcaa tgaccatgac tttggtgaaa aaggtgtgct gaccatgcgt caagctcttt
    21301 catggtcaag taacgtcggg atggtcatac tggaacagcg attaggcgga cgatggtata
    21361 actatttaca aaaactggga tttggacaaa gtactcattc tggattagat gatgaagtaa
    21421 acggtgcttt acctacatta aatattgtcg accgagcaat gagtgcttat ggacaagcgg
    21481 taggtgtgac gaatttccaa atgatgaaag ctttcacttc tattgcgaat aacggtacaa
    21541 tgattcaacc tcgatatatc agcaaagtgg tggatcccca aactggagaa gagcgaacaa
    21601 ctcaaacaga agttctaggg caaccttttt caaaagaaac aacagaaaaa gtccgtgaat
    21661 atatgagaga tgttgtcgaa agcgaaaact acggtagtgc ttatggtgta tatagtgtac
    21721 ctggatacaa tgtatcggca aaaaccggaa cagcccaaat cgcttctgat acagggggat
    21781 atcaaacagg agatacagcc tacctgtatt cgattgtgga gatggttcct tctgaagatc
    21841 cagactatgt cttgtatcta acaatgaaac accctaagac atatgatcga atggcattgg
    21901 ctaaaatcgc aaatccattg atgaaacggg caatggattt taaagaaact gaagaagatt
    21961 cagatacaga aacaaaaaca gaaaaagtat ccgtagccga ttatcgtaat cttgaagcgg
    22021 acgttgcagc agctgatgct caaaaaagtg gactgcaacc tgtagtgatc ggtaatggta
    22081 aaaaagtaca aaaacaatct actgccaacg gtgatcagtt gatctctgga gaaaaactga
    22141 tcctatatac tggtggtgat aagctgatgc ctgacgtaac aggatggtca aaagcagata
    22201 tcatgaagct ggggaaaatc ctcggtattg aagttagttt tgatggagat ggttattgtg
    22261 tcaaacaaga acttgctcca tatgaaaaaa tcactgaaga caaacttagt tttactttag
    22321 aagaataaga agagaaatag gagagaaaag agcatggaat ggacacaagc attgattccc
    22381 attgtcagca gttgtgcaat gacaattgcc gcaatgccgc tatttattgg ttattttcaa
    22441 atgaaaaagc aaggtcaggc gattcgtgag gagggaccaa agtggcacaa tagcaaagcc
    22501 ggaactccta caatgggcgg cttagtgttt ctgatcggct ctattttgac aggaatttgg
    22561 gttggagctt ggcaaaaaca gctaactcct actcttttca tcttgctttt tgtattagcg
    22621 ttatacggag taatcggctt tcttgatgat tttataaaaa tattcaagaa aagaaacatg
    22681 ggactgaact cgaagcagaa attgattgga cagattctag ggggaatcat cttttatctt
    22741 gtttaccgtt ctgaaggtta tccaggtgta ttgaatttct tcggactaga tctaccttta
    22801 ggaatcattt atggtatttt cgctctcttc tggcttgttg gattttcaaa tgcagtaaat
    22861 ctgacagatg gcatcgatgg attagttgct ggcttaggaa gtatctcttt tgcagcttac
    22921 ggtctaattg cttggcatca gcatcagtat gatgtattaa tcatttgctt aagtgtttta
    22981 ggaggtttac tgggtttctt cgtctacaac agaaaacctg ccaagatttt tatgggagat
    23041 gtcggttcat tagcgttggg cggactttta gcggcaattt ctataatgct aaaccaagaa
    23101 tggacattgc ttttgattgg tttgatctat gttatggaaa cagcaagtgt gatgcttcaa
    23161 gttacttcct ttaagcttac aggaaaacga atttttaaaa tgtctccaat tcatcatcac
    23221 tttgaaatgt gcggatggtc ggagtggaag attgatacag ttttttggtt gatcagcatt
    23281 gtgacttcgt tgatcacatt atggatcgtt tggtaggaga tgacgggaaa tgaaaaaaat
    23341 atcaacatat gaaaataaga aagtgcttgt cttaggactc gcaaaaagcg gagtaagtgc
    23401 ggccaaatta ttacatgaat tgggcgcact tgtcaccgtt aatgatggaa aaccttttga
    23461 cgaaaatccg gaagcacaag agctgctttc tttagggata aaagtaataa caggtagtca
    23521 tccaatcgaa ttgttggatg aagaattttc attgatggtc aaaaatccag ggattcccta
    23581 cagtcatcct ttagtagcaa aagcccaaga aatgggtatt ccggtaatta cggaagttga
    23641 gctagcttac gaagtagcgg aatgcccaat tattgggatt acaggaacga acggaaaaac
    23701 aacgacaaca acgatgacag gactactact gaatgcagga gcagatcaag gaattgcacg
    23761 tttagcgggt aatattgggt atccagcaag tggtgtagcg caagaagcaa aatcagaaga
    23821 taaaattgtg atggaattgt ctagcttcca actcatggga atcacagatt tccgccctca
    23881 tatagcggtg attaccaata tctatgaagc acatattgat tatcatggta caagaaaaga
    23941 atatgtcaaa gctaaatgga accttcaaaa aaacatgaca gaaaaagatt atctgatcct
    24001 taactggaat cagtcagaac tacaagaatt agcgcaaaga acaaaagcac gcgtactgcc
    24061 tttctcgaca aaagaagtgt tggaagacgg tgtgtatgct gacgattact caatatacta
    24121 taaaaaagaa aaaataatgg aaatatctga acttggcgta ccaggtaagc ataatgtaga
    24181 aaatgcacta gctgctattt ctgtagcaaa attgtatggt atatcaaatg aagctatacg
    24241 agaaacgttg cattttttcc atggcgtacc acatcgtacg caatatgtag gagaaatcca
    24301 aggcagaaaa ttttataatg attcaaaagc aaccaatatt ttagcgacta aaatggctct
    24361 aagtggattt gaaacgtcta aggtcgtgtt attggctggc ggattagaca gaggaaatac
    24421 atttgatgaa ttaattcctt cattaaaagg aatcaaagca atggtcgtat ttggccaaac
    24481 aaaagaaaag ttgatggatg ctggaaaaaa agcaggcatc gagacaatag taacagccga
    24541 ttctgtagaa caagcagttc ctttagcatt agaaaacagt acagatggtg atgtagtttt
    24601 attatcacca gcgaatgcca gctgggatca atacccaaat tttgaaacta gaggaaacag
    24661 attcatggaa gctgtgaacc gattaaaata gaaaaagtag aagcgagcga taaaaaatga
    24721 aaattttggt tacaggcgga ggaacagggg gacatattta tccagctctt gcctttgtca
    24781 attatgtaaa gactcaagaa ccgaatgctg aattcatgta tgtgggagca aaacgaggtc
    24841 tagaaaacaa aatcgtccct gatacaggaa tgcctttcca taccttggag attcaaggat
    24901 ttaaacgaaa aatttccatg cataacatca agacggtccg attgtttctt aagagtatcc
    24961 gtcaagcaaa aaaaatcctc agtgattttc aaccagatat cgttatcggt actggaggat
    25021 atgtttccgg agcggtagtg tacgctgcag ccaaaatggg tattccaaca gttatccatg
    25081 aacaaaacag tgtaccaggt gttaccaata aatttttaag ccgatatgtg gatcggatcg
    25141 ctctttcatt taaagatgcg gcttcctttt ttcctgaaaa caaagcagtt cttgtaggta
    25201 atcctcgagc acaagaagta gcagatacta aaaaatcaga tattttgaaa acatttgatt
    25261 tggatccaga aaagaaaaca gtcttgattt ttggcggtag tcaaggagca cttaaaatca
    25321 atcaagcagt atcagttttt ttaagtgaat atattccttc ttcttaccaa gttttgtatg
    25381 cttcaggaga tagatattat gaagagatcc taaataaaat aaatcctgaa atacaaaata
    25441 ttagtgtcca gccttatatc aaaaatatgg cagaggtcat ggcttccagt gatctgctgg
    25501 tggggcgtgc tggtgcaact tcgatcgcag aattcacagc tctggggtta ccggcagtgt
    25561 tggttcccag cccatatgtt acgaatgatc atcagactaa aaatgcaatg agtcttgttc
    25621 acgcaggagc agcaaaaatg attgcagata atgaactaac aggtgaatca ctaagtcaga
    25681 cagtcaacga aatcatgggt gatgaagaat tgcaaaagca aatgtgccga gcttctaaag
    25741 aacaaggaat ccctgatgct tcaaaacgtc tttatgactt agtaaaacaa ataatcaaaa
    25801 aataaaggcg gtggtcttag tgagtaagaa aaaagaacca aaaaaattgt ctcatccgtc
    25861 ttctgatgaa aacaatttga ctccttggca aaaggctaac cgaaaatatc tggcagaaca
    25921 agagatgaaa aaccaagagc caaaaaaaga agacataaca ttagatacac ccctttcaga
    25981 ttctgaagaa gaaaaaacgg ttcaagagga acagcaagaa gaaagccagt ccgagaaaaa
    26041 aatcgaattt tttgaagaga tcaagcaaaa gaaaaacggt ggaccatata acggttcttt
    26101 tttgaaccgg ctgcccaatt taaaaagtca acggcacaaa gtactatttc gtcggttagc
    26161 tttgatcatc actgtattgg gtataccgct gatttttttg atctattatg tttctcctta
    26221 tagcaaatta caagcagttg cagtatcagg caataagaca gtcaacagcc aagaaatcat
    26281 ctctgataca aaattgtcat taggagaaaa tgtttgggga cagtattttc atcgatctac
    26341 ttatatcgat cgccttaaaa aagcacagcc aagaatcgaa acagcaaata tacatttcaa
    26401 agggatgaat gaattcgatt tggatgtaac agaatataaa gagattgctt tgatcgcaaa
    26461 aaacaatcaa tactacccag tgattgaaaa tggaacagta ttagatgaaa aagtagcaaa
    26521 tcctacaaaa aatctcccta tcttggaaga gttcaaagac tctgcaaaaa tcaaagaatt
    26581 aacaaagcaa tacaatcagt tatcatcaga attacaaaaa gcaatttctg aaatcaagta
    26641 cacgccaaga gcaagcaata aaaatctgat ccaattgaat atgaatgacg gcaatcaagt
    26701 tattgtaaat atcaataatc ttgcgaacca aatgaaatat tattcgcaag tagccaaaga
    26761 tatggatgaa aaaggtgtga tcgacatgga agttggtatc ttctcgcatc cttacggtag
    26821 cactcaagaa acggaagaat cgggccaatc ggaagaaaca actgaaagtg aagaaaatgc
    26881 ggatcaaaca aacgaatcaa gtgaagaggc agaaacgcaa aaagcacaaa cacctggatc
    26941 gtctagcaca aacggatcat ctgattcaaa tgattcaagt gaaacaagtc aaatagaaga
    27001 taatccaagt acaactccgt caagtttaaa tgaaaattga taaaacaact ttaaaaagta
    27061 agaatgtact ttctaaaaac cagtaattta tggtagaatt ggaagcagtg aatatatcta
    27121 ttaataagta tattttaaaa cggacgctag ttgttcgctt gtatatggaa tagtaagtag
    27181 gagggaatcc cattcatggc aaaaacagga atgtatgtag gccttgatat tggaacgaca
    27241 tctgttaaag ttgtcgtggc tgaatatatc gacagccaaa tgaatattat tggagtagga
    27301 aacgcaaaat cagaagggat taaccgaggc attatcgttg atatcgataa aacggtccaa
    27361 gcgatacaac gagcagtacg acaagcagaa gaaaaagcag gtatccagat caaaggcgta
    27421 agtgtcggtt tgccagcaaa catgcttgaa gtagaaaatt gccagggaat gattgcagtt
    27481 aacggagatt caaaggaaat caccgatgaa gatgtcagaa atgtggcttc agctgccctt
    27541 gttcgttcaa tacctcctga acgtcaaatc gtgtcaatat tgccacaaga ttttactgtc
    27601 gatgggttcg agggaatcaa agatcctcgt ggaatgatcg gcgtaagatt agaaatgtac
    27661 ggtctgttgt ttacaggacc taaaacgatc atccataaca tacgtaaatg cgtggaaaat
    27721 gccggattaa tcgtcaacga aatggtgatt actcctttag cgctgactga atcaattctt
    27781 tctgacggag aaaaagattt tggtacgatc gtcattgata tgggtggcgg ccaaacaaca
    27841 acggctgtta tgcatgataa gcaattgaag tttaccaatc ttgaccaaga aggtggcgaa
    27901 tttgtcacta aagatatctc tattgtatta aatacgtcat ttaacaatgc agaagcgttg
    27961 aaaataaact acggggatgc atacccagaa cggacatcac cagatgaaga atttccagta
    28021 gatgtgattg gtcagtcaga accagtgaaa gtcgatgaac gctacttgtc agaaattatt
    28081 tcagctcgaa tggaacagat tttcaacaaa gcaaaagatg cattggacca aatcgaagca
    28141 ttagagttgc caggtggcgt cgtattgaca ggcggagctg ctagtcttcc tggtgttgtg
    28201 gacttggcac aagaaatctt cggcgtaaat gtaaaattgt atgttccaaa tcacatgggg
    28261 ctgagaaacc cggtatttac aaatgtaata agtatcgtgg attattcagc aaacttgagt
    28321 gaagtgtatc aattggcaaa aattgctgtt acgggtgaaa cctcagcagc tcgtcaaatg
    28381 gtagttgaac aagaaacaac aaacacatat gagagctatg aagcacctga agaaacaatc
    28441 tacgatgagc cggaaccaaa agagtccgga gaaaatgtaa aaaataaaat caagggtttc
    28501 tttacaaata tttttgatta attcatcctg ggaggaataa gatatggaat tctcaattga
    28561 taataatatc aatgacggcg cagtaatcaa agtcatcgga gtcggtggtg gcggtggaaa
    28621 tgctgtaaac cgaatgattg aagaaaacgt taaaggtgtt gaattcatta cagccaacac
    28681 agacgtgcaa gcattaaaaa attcaaaagc tgaaacagtt atccaattag gccccaaata
    28741 tactcgtggt ttaggtgctg gttctcagcc agaagttgga caaaaagcgg cagaagaaag
    28801 tgaacaatcc ttacgcgaag ctttagacgg tgcagatatg attttcatca ctgcaggaat
    28861 gggtggagga accggtacag gtgctgcacc aatcgttgca ggtatcgcga aagaattggg
    28921 cgcattgact gttggtgtcg tgacacgtcc attcactttt gaaggaccga aacgtggccg
    28981 ttttgctgca gaaggtatcg ctcgtttgaa agaaaatgtg gatacattat taattatctc
    29041 aaataaccgt ttattagaag ttgtagataa aaagacaccg atgcttgaag ctttccgtga
    29101 agcagataat gttttacgac aaggtgtaca aggtatctct gatttgatca cagcgccagg
    29161 ttacgttaac cttgactttg ctgacgtgaa aacagtgatg gaaaaccaag gtacagcatt
    29221 gatggggatc ggtgtggcta gtggagaaga tcgcgtagta gaagcaacga aaaaagcaat
    29281 ctcctctcca ttgcttgaaa catctattga tggagctgaa caagtacttc ttaacatcac
    29341 aggcggtttg gatatgacat tgttcgaagc acaagatgct tcagatatcg tagcaaatgc
    29401 agcaactggc gatgtaaata tcattctagg tacatctatc aatgaagaaa tgggcgatga
    29461 aatccgtgtg acggtcatcg caacaggtat cgatgaatca aaaaaggaac gcaagtctag
    29521 ccgaccagct agacaagcac aaatgcaatc acctgctcaa aagactgtat tagatatgga
    29581 tcaagctaaa ccaacttctt cagaagaaga aaacagtttt ggcgattggg atatcagacg
    29641 tgaacaaaat gttcgtccta gagttgatga ttccaatttt gacaatatcg aaaaaaaaga
    29701 atttgataca ttcaaccgcg aagaaacaaa atctcatggc gatgatgaat taaatacgcc
    29761 accgtttttc cgtcgtaaaa aataaaggag aggaagagca catgattgct gacaacttgc
    29821 agaaaatcaa gcaagaaatt caggattcgt gtgctcttgt tcatcgtgat ccgaaagaag
    29881 ttacattagt agctgtaaca aaatctgttg aatccgctca agctgaagaa ttggttagag
    29941 ctggcgttat gaattgtgca gaaaaccgag tagataaatt attagaaaag aaacaagatt
    30001 tatttgattt tcctgaaata aagtggcatt taattggtaa tttacagcgc agaaaggtaa
    30061 aattgattgt aaatgaaatt gattactttc atgcgttgga cagtttaaga ttagcagaag
    30121 aaatccagaa gcggttagag aaagaattat cctgttttat tgaagtaaat gtttctggtg
    30181 aggaatcaaa acatggaatt tcaccagatg agcttttacc gtttgtggaa tctttagctg
    30241 cctgcacaaa aatcaaggtt gttgggttga tgactatggc gcctaaagaa gcttctgatg
    30301 agcaaatcca taaagtgttt ggtacgctga aagaattgcg tgatcttgtt caagcaaaag
    30361 gttatgccca tgcaccatgt agtgaattaa gtatggggat gagtcaagac tttcaaattg
    30421 cgattgaaga aggtgcaaca tttatccgtg taggaacagc gctattcaaa gacgaataaa
    30481 ggaggaacaa aaatgccgct tttaaacaga ggagcaattg ctaatttttt cggattagct
    30541 gatgaggaag agtacgaata ccaagattat cctgaaacaa caaaaaaggc tgtacagcca
    30601 actaaaaaaa atacaacaca gaatcaatca actcattctg tatctgctgc gaatactcat
    30661 gaaaaacaaa aaacggcgac ttcacgtcct gtaacgcatg aaagtattca gccggctgaa
    30721 aagaaaaaag taattgaact acatcaatca cctacaaaaa ctgtagcgaa agaaagaaca
    30781 gcttcaagaa cctctacaca acctaaagca aatcttgctg gaaaaatcac tgtaatggaa
    30841 ccaagagctt attctgaagc tatggcgatt gctaaacgaa tcattgctgg agaagcaacc
    30901 ttagtgaatt ttcatttagt agaagaaaaa caagcgagaa gaatcgttga ttttctaaca
    30961 ggaacagttt atgcactaga tggagatatc aaacgtgttg gagatgagat ttttctttgt
    31021 acaccgactg ggatggagat tgacagttca accgctcaat cttttgcaga tgcgaatttg
    31081 tttgatctgt aagaggagga actacgattt atactattgc actattactt catttacttc
    31141 aacgggcagc ctatttctat agcattatct tgatggtata tgcattgctc tcttggtttc
    31201 caggcgggta tcaatcaggg ctaggacgat tattagctaa gatctgcgaa ccgtatatca
    31261 gtttgttcga tcgtctgcct ttgaggattg gacccttgga tttcacaatt ttaggggcaa
    31321 tcctgatctt gaacttagcc gtacaaggtt tagcacagat cgttatatgg ataactgtcc
    31381 atttagttta ttgattgaag caacaaaatc tttattctca gaatagatag gaggggaaaa
    31441 ttttggatgc aaatgtatac cagcactttc gggcagatga acgtacattt atcgattcgg
    31501 taggcgattg gattgaacag gttcaaggac aatatgcacc ctatctgacc gaatttcttg
    31561 acccaagaca atcctatatt ttagaaacac tgattcgaca aagcagtgat ttgcgtttca
    31621 tgttttatgg cggatatgaa caggcagaaa gaaaaagatg tttgattttc cccgattatt
    31681 acgaacctgt agaggaagat tttgaaacag cattgtatga aatccattat cctagcaaat
    31741 ttgccagcct aagtcatggg aaaatccttg gaactttagt gggaacgggg atcaaacgct
    31801 cttactttgg cgatatcatc tcggacggtg atcgctggca agtatttatt gcaaatgagg
    31861 tggatcattt tgttgctgca caagtaacaa agattggaaa ggttgctgta cgcttggaac
    31921 caatcaaata cacagaaatg attatgccga aagatagctg gacacaagaa agaggaacag
    31981 ttagttccat gcgactagac agtgtgatct ctgagattta taatatttcc agacagcggt
    32041 ccaagcagct gatcgaagct ggtaaagtaa aagtgaactg gacagaaaat acaagacctg
    32101 attttgtact tgaactatta gatattattt cagtcagagg ttatggcaga gtccagatcc
    32161 aagaacttga ggggaagacg aaaaaagaaa agtacagggt actgttcggt gtattacgta
    32221 aataaaataa aaaggtggtt tactcatggc tttaactcca ttagatatcc aaaataagac
    32281 attcccgaca aaaatgcggg gatataatca agacgaagta gatgatttct tagatttagt
    32341 tgttcgtgac tatgaggaat tgactcaaag aaatcgagaa ttagaaaaag cagtcaaaca
    32401 ttctgaagaa aaacttgagt acttcaatga attaaaagat gctttgaacc aatcaatcat
    32461 cgtagctcaa gatacggctg ataaagtaaa aacaagtgca agcaaggaat ccgaagtgat
    32521 cgttacttct gcacaaaaca aagcagatga gttagttgcg aacgctgaaa aacgtgcaca
    32581 tcaattaaca actgatgcag aagaaaaagc aagaaaaatc ttgacagatg caacagaaaa
    32641 agcaagacag cttgcgacag aaactgaaga tcttaagaaa aaaacacgag tattccatca
    32701 acgtatcagc ttgatgcttg agtctcaatt agaacaagtg aaaagtccgg aatgggatga
    32761 aattttacaa ccattctcca gctacgtgac tgacagccat gaagtgatca aagaagtttt
    32821 agcaaaacag cttgacaatg aaaatgatac tgatgtaaac tcagacacag gagtcataga
    32881 agcacctatg acggcatttg atacacaggc tattgatatc tcgatcgtgc ctggtgaaaa
    32941 tgaaaacgag tagaacagaa aagcactttg ttattcttaa agcgagccga tgagagtgga
    33001 agttcggtaa gacactgcat ggtgaaagat cctctacttg agacctgctt ttccgaaatt
    33061 agagtaagaa gcagcggctg acctcgttat tggtcacaga gagtttgcac tagatagatg
    33121 caactaaatt tgggtggtac cacggcatgt tcgtcccttg cggctgaaca tgcttttttg
    33181 tgtccggaaa acaaataaag gagtgtatgg ttgaatgaaa atgaaagaaa ccttgcaatt
    33241 aggaaaaaca aaattcccta tgcgtggtaa tttgccaaac cgagaaggcg agtggcaaaa
    33301 agaatgggaa gaaaatcgaa tctaccaaaa aagacaagag ttgaacgaag gaaaacctag
    33361 ctttgttctt catgatggac ctccatatgc caatggtaat atccatttag gacattcatt
    33421 gaataaaatc agtaaagaca ttatcattcg ttcaaaatca atgtctggct atcgtgcacc
    33481 atatgttcca ggatgggata cacatggatt gccgattgaa caagtattgg ctaataaagg
    33541 cgtgaaacgt aaagaaatgt ccatggcaga atacttggaa aaatgtcgtg aatatgcact
    33601 ttcccaagta gataagcaac gagcagattt caaacgccta ggagttgcag gagattggga
    33661 acatccttat gttacattag atccttctta tgaagctgca caagtacgcg tatttggtaa
    33721 aatggctgaa aaaggctata tttacaaagg attgaaacca atttactggt ctccgtcaag
    33781 tgagtcttct ttagcggaag ctgaaattga atataaagat gtaaaatctc catctatttt
    33841 tgtagctttc aatgtcaaag acggcaaaga tattcttgat gaagatacag cttttgtcat
    33901 ttggacgaca acaccatgga cattgccagc aaaccaaggt attgctgtaa atccaaaatt
    33961 tacgtatgta ttggtggaag ccgatggccg taagtttgtc gtagcgaaag atttgctaga
    34021 aacagtccaa tcagaaatcg gttgggaaaa tgtaacagtt ctaaaagaat ttgctggaca
    34081 agaaatggaa tatatgactg caagtcatcc attctatgaa cgtgaatcac ttgtgatttt
    34141 aggcgatcat gttactttag acgctggtac tggattagtc catactgctc caggacatgg
    34201 ggaagatgac tatatcgctg gtagcaaata taaactatct gtagtgtcac ctgtagactc
    34261 aaaaggattg tttacagaag aagcacctgg atttgaaggt atcttttatg acaaagcaaa
    34321 tcctatgatc actgatctat taaaagaaaa aggagctttg ctgaagctag atttctttac
    34381 tcatagttat cctcacgatt ggcggacgaa aaagcctgtg atctatcggg caactccaca
    34441 atggtttgca tctatcgata aattccgtca gaatattttg gatgaagtag aaaaagtaga
    34501 gtgggttatc ccatggggta aaacacgttt gtataatatg atccgtgacc gcggcgattg
    34561 ggtaatttcc cgtcagcgtg catggggagt accacttccg attttctatg ctgaaaatgg
    34621 agaagcaatc atcacaccag aaacaatcga acatgtggca aaattatttg ctgaacatgg
    34681 atcaattatc tggtttgaaa aagaagcgaa agaacttctt cctgaaggat ttacccaccc
    34741 aggttctcct aatggcgaat ttacaaaaga aaaagatatc atggatgtct ggtttgattc
    34801 tggttcttct catgaagctg ttttacgtca gcgaccagaa ttatcattcc cagcagatat
    34861 gtatttagaa ggatcagacc aatatcgtgg ctggttcaac tcaagtatca cgactagtgt
    34921 ggctatcaat ggtgtagcac catacaaatc agttatttct caaggatttg ctttagatgg
    34981 tgaaggccgt aagatgagta aatctttagg aaacatcatt gcaccagaaa aagtgatcaa
    35041 acaatttggt gcagatatcc ttcgcttatg ggtatctagt gtagattatg aagcagatgt
    35101 tcgtgtttct atggatatct taagtcaagt ggcagaagta tatcgtaaaa tcagaaatac
    35161 gatgcgtttc ttattagcga atacagaaga tttcgatcct aaaaaagata ctgtttcgta
    35221 caatgattta cgttctgtag acaaatatat gaccgttcga ttgaaccaag taatcaaaga
    35281 aatccgagaa gaagggtacg acaaatataa cttcatgcat atttaccgta cagttatgaa
    35341 cttcttgacg gttgatctat cgtcattcta cctggatttt gctaaagatg tagtttatat
    35401 tgaagcagaa gatgattatc aacgtcgttg catgcaaact gttttctatc aaacagctgt
    35461 agctttgaca aaattattga ctcctatcat tccgcataca gcagaagaaa tctggtcatt
    35521 cctgaaagaa gaagaggagt acgttcagtt aagcgagttt cctggttatg aagagtttgc
    35581 aaaccaagaa gaattgatgg atacctggac tgctttcatg gacttccgtg ataatgtctt
    35641 aaaagcattg gaagaagcaa gaaacagcaa attgattggt aaatctttgg aagcaaaact
    35701 aactgtttat ccaaaacaac aagttcgtga aatgttaaaa gctttggatg cagatattgc
    35761 acaattattg atcgtttcac cagactactt tgaagttatg gcagcagatg aacaagtgcc
    35821 agataacgct atggtatttg atgatgttgc tattacagtg gaaaaagcag acggggaaac
    35881 ttgcgatcgc tgtcgccaag ttcgtaaaga tgtaggagta gatgaaaaac ttcctcatct
    35941 atgcggtcgt tgtgcaaaaa tcgttgaaga cttctatcct gaagctgtag ctgaaggatt
    36001 cgaagaaaag taaaagggaa aagggggtgt gacatgttct ttgtcacacc cccttttgtt
    36061 atcaatcgtt taattttcca cgttcacgat accagttatc tggttgccag atccattcga
    36121 atccgtcttt ttcaagtagt tcgaaagctg ctttaggtcc cattgatcca gctttgtagt
    36181 tgggaaaatc cggttgtgtt tggtcccaag cttttcgaat gacatccacg atatgccaag
    36241 attgagcgac ttcttcccaa tgagagaagt tcgttccatc accattcaac gcatctaata
    36301 gtaatttttc gtaagcttct gggctatttt caaccatttc tgcactattt ctaaattcca
    36361 atttgattgg ttccgtttca aatccttgcc ctacttcttt cccattcaag gataaagaaa
    36421 atccttcagt tggctgaata tagatcgtta gaacattagg tggaagtgtc gtatcgtcac
    36481 atggttcatc gacagatgtt ttgaatacat taacaggaac ttgtttgaat acgatgttga
    36541 tccgagtccc tttttcagtc aaacgtttgc ctgtacgtac atagaaagga acacctgacc
    36601 aacggaagtt atcgatagtg aatttgcctg cgacgaatgt ttcagtctct gattgagcat
    36661 ccactttgtc ttcttcgcga tagcccttga attgtacacc atccaattca ccttgagcat
    36721 attgcccgcg aacgaagttt tctaacactt cttcttcgtt ataaatgcgg atagctttca
    36781 atgctttgat cttttctgta cggatttctt tttcggaaaa tgctactggc ggttccattg
    36841 caagtaatgc tacaacctgt aaaatatgat tttgcaccat gtctttaagt gcgccactat
    36901 gatcgtagta gcccccgcga tcttctacac cgaggttttc gccaaaagta atttggatat
    36961 tgtcgatata gcgattgttc cattgagcct caaaaatatt attggcaaaa cggatagctg
    37021 agatgttttg gatcatttct tttcctaaat aatgatcaat cctgaaaata tcttgttctg
    37081 ggaatacttc tctgatttgc tggttcaatt caaaagcaga ctggtaatca gaaccgaacg
    37141 gtttttctat gatcaaacga ttgaagccat tttttgtcat aatattttgt gatttcaaat
    37201 gagaaacgat cgttccaaaa aattgaggtg ccatagccaa ataatagaca cggttaccgt
    37261 ttaattgata gtgtccatct aatcggtcag acaattcttt taatgtctga taatgcgttg
    37321 aatcatttac atcatgggat tgatagtaaa aatggcttgc aaaggtagtt gcttcttcat
    37381 ctgaaggatt caatgcacgg attgtttctt tgacaacttc acggtagtgc tcatcgctcc
    37441 agggacggcg agcggttccg attacagcaa aatgctcgcc taaatttcct tttctgtaaa
    37501 ggcggaacaa agacgggtac aatttacgct gggctaggtc acctgtaccg ccgaatatcg
    37561 taaacaatac atttttttca ttagacatgt ggatacactc ctttatattt tatcgacaaa
    37621 aatcgtgctg gccgccttaa agctgacggg gattttcttt ctatcatttt ggatagtgat
    37681 cggtccttca taagctgcga tgtcaacgat ctcatattct tcgttgatat tcaggtcaat
    37741 agtgactaag taatccaaca attctttttc atcaagcact cgtgcgatac gcacttttgt
    37801 accgacagga taggactcca atgtttgtcg gcgttcttca tggacaactt cctctttttt
    37861 aggaatcgat cctccatgag gacaatgttc aggatgattc aaatagtttt ctaaatgatc
    37921 tgcaagatgt tccgaagtca catgttccaa tacttcagca tcatcatgga cttcattcca
    37981 gctatagtct aaatgttcaa ctaaaaaaac ttcccataag cgatgtttgc gaatcagact
    38041 gctagctttt tgcagtccgc ttgcagtcaa ttgtacacct tgataagggg aatgttctac
    38101 aagctcttct ttcacaagtt tagaaatcat ttcactgaca gatgcagctg agacatctag
    38161 actagatacg atttgtttat tgttgacttt cgttgtatct ccacctagtt ctaaaatgat
    38221 tttcaaataa tcttctcgat ttggtgtcat attcgatcat cctttcatgg taaaaaacca
    38281 tcattagtaa gtgtaacaaa aaaaacgtta attgactatt tttctaaata aaaaacaaag
    38341 gatttttaga cgtttttaca acaaaaaacg aaagatgata gagaagactc attctttcgt
    38401 ttataaagga tatatatata cattgggagg gatctatttt tcagataaca acttatatga
    38461 agtgtctgca gattcgtcat aaagagtttg ttcgggataa gaaaagataa gataaaaacc
    38521 atactgatca cgtacgacta aacgatattc atctatttct accacagatg tgccaagaga
    38581 ctgaccgttg atcaaaaacg tgtaatcaga tgtaatctgt aattgttgtt tttgctggct
    38641 atcactaaag aaccatgtac cttgatactt tgagagtcct tctgactttt ccgcttgttt
    38701 tttctttttc aagtaaataa aacttgagag aacggtaatg agtgaaccaa gaaaatagat
    38761 catttttttt atcaccaaat cactccttta tgagaaaata atcgcataga catattcttt
    38821 cttctttatt tcattgtacc gaataaaagc taaaatttct ctaagacttt cgactggttt
    38881 ttttactgtt tttctacaaa ttatgatagg atacatagta ggaagaaagg tgacataatt
    38941 tgaagtatca gcaagtggaa atagcttttt ttattgaccg cccgaatcgg tttatagcac
    39001 attgtatgaa aaaagacgga gaaataatta ttgcgcatgt caaaaataca ggtagaggaa
    39061 aagaggtcct gataccaggc gctgaagtgg ctattgtatt tgctcctgga cctaaacgga
    39121 aaaccgccta tgatctgatt gctgtaaaaa agaagggtga ctggtttaat atcgatagtc
    39181 aattgcctaa tcggctggca attgatggta ttttagacgg cacgatcctt ttaccaggat
    39241 taactggtcc atttacggta tacaagcgtg aagtaactta tcttcactcc aaatttgata
    39301 tttatttaga gacggtggtc ggacaaaaag catttgttga agtcaaaggt atgacacttg
    39361 aaaataaagc gattggtgct tttcctgatg cgcccacact cagaggattg aaacatatag
    39421 gagaattaac gtatgccgca caagatggtt atgccgctta tgtcttgttt attgctcagt
    39481 tcgaacatct tcatctggca acgatccatg aagaaatgca accagcacta gctgatatgg
    39541 ttcgacatgc gcagcaaagc ggagttcaaa tcctcgccta taattgtcaa gtatcggcag
    39601 atgaggtaac tgtcaagcag gccattccat ttgatgtaga tatccctttt gaagatccta
    39661 tacaatagaa agaaggtaaa ataatgatca acttaggtat tatcggaaca aattggatta
    39721 ctcatcaatt tgtccaagca gctttaagca caaaaaaata tgaattgaca gcggtatatt
    39781 ctagacattt ggaaaaagca caggaatttg gttctcatta tgaaggggat atcgaattcg
    39841 caacagattt gaagactttt ttcaatatta ctcatatgga caccatttat attgcttctc
    39901 cgaatagtct tcactttagt caagctaagc aagcaatttt ggcaggaaaa aatgtgatag
    39961 ttgaaaagcc agctttttcg acgccaaaag aaatggatga aatcatccat ttggcaaatg
    40021 aacacaatgt gtattttttt gaagcagcaa gaaatatcca tgaatcaggt tttaaaaaga
    40081 ttgccgatta cttaccatta aaagacgaga taatcggtgc aaatttcagc tatatgaaat
    40141 attcttcgcg ctatgaccaa gtattagatg gagaagaacc gaatatcttc tcgactcatt
    40201 tctcaggtgg tgcattgatg gatttaggtg tttaccttgt atatgcagct gttgcttggt
    40261 ttggaatgcc aaaagaagtc cattatttcc caagaaagat ttctactggt gtagatggtc
    40321 ttggatgggg gatcttacgt tatgagaatt ttgatgtatc gatccagcca ggtaaaatcg
    40381 gtgattctta tttaccgtca gagatttatt ttgactcagg aacgctagtg atgaatggag
    40441 tcaatgcaat tgaacaagca caatttcatg atcgcgcgca taaagaaatc attgatttgg
    40501 cggtaacagc tgcagaaaat ccaatggcag atgaagcaga ggattttgcc aatgtcatgg
    40561 ctcatccgaa agatccagct tggggattgt tgtatgaaga gtggatcgag ctagctagaa
    40621 atgtgaacca agtgatttat gatttaagaa aaaatggcgg catcaaattc gatgcagata
    40681 atgaggaaga tttttaatga acgaatttgt acaagtattt cccgaaaatt ggcagaaaaa
    40741 atatgaggat aaagggttta tctcaccttc tcttattcaa cgagcagttt ttcagccact
    40801 aagtaataaa caaagtatag tagcggtttc tcctacaggt tcaggtaaaa cactggctta
    40861 tctttggcct ctactactaa acgtggaacc aggtgaagca agtgcgttgg tcatttttgc
    40921 ttcttctcaa gaactagcta ttcaagtagc agatgttgca cgtgaatggg gaaaagacaa
    40981 agagttgaaa gtccaatctt tggtgggcgg agccaacgtc aaacgtcaga ttgagggttt
    41041 gaaggaaaaa ccagaaatct tgattggtac accaggaaga atattggaat tgatgaaagc
    41101 aaaaaaaata aaagcacatc aagtgaaaac aatggtattt gatgaagcag accagctatt
    41161 tgacgctggg aacagccaaa tcattgatca aattcttcat caagctccaa cagagtatca
    41221 gctagctttt ttttcagcga cagcagatcg ttcccttgaa agcattgaaa aaatcactgg
    41281 gaaaacgttt gagacaattg acgtgacagc agaggacgat tctcgaaaag gactgagaca
    41341 ttacttttta cgtgtaccga tacgaaagaa agatgactac ttgagacgtc tcacgcatat
    41401 agaagatttt catggtctga ttttctttaa tcaactgact gaattaggcg taatggaaga
    41461 aaaattgctg tatagaggtg taccggtagg aagtctggcc tctgatcaga acaagctact
    41521 ccgaaaagca gcgctagaac aattcaaaaa gaaaatggtc agagcacttt tgaccacaga
    41581 tgtggcggct agaggtttag atattacagg tcttccttat gtagtgaatg cagaagttcc
    41641 gttaagtgaa gaagcttatt tgcatcgttc gggaagaact ggtcgaatgg gtaatgaagg
    41701 aatagtaatt acactcgtac aagataataa tctaagagat ttaaaacggc ttttacgtcc
    41761 atcaaatata acacttgaag agattttttt atacggaggt aagctgcaaa ctgagcagcc
    41821 aaccaaagaa gatgcagctc ctgcagtaaa taaaaagtat gcgaaaactt tttctggaaa
    41881 ggagcagaac ccagaatata acaaagaaaa aataagaaaa aaagttaaaa ataaatcaaa
    41941 aaaagagaga aataaaggag caaggcgcaa ataagcgcct ttttatgcta tgattatgaa
    42001 aacgggaaca aaattggttg ccagaggagg ggttatgtga aagaacgtca agaagagatc
    42061 ttgcagctat tgacagaaaa ccaacaagga ttgacagcaa gtgatgtagc tgagcgctta
    42121 actatcgatc gaagcaatgc aagccgatat ttaagtgaac tatacaaggc ccatcatatt
    42181 gtaaaaaccg ctggccgacc agtcgtttac tctttgccaa cggaaaagtc aaaatctgat
    42241 gaagtgcatg tcgactcttc tacgcaagtg acttttgaaa cactcgttgg agaaaatgat
    42301 tctttaaaag tcagcataca gcaggcaaaa gctgcgattc tttatccacc gcgggggttg
    42361 catacgatta tttttggaga aactggtaca gggaagtcga tgtttgctga atgtatgtat
    42421 cattttgcaa tcgattcaga gatgctttct gcagatgcgc catttgtttc tttcaattgt
    42481 gcggattatg ctcaaaatcc gcaactgctc tttggacaca tctttgggat caaaaaaggg
    42541 gcttacacag gagcagctca agatagtccc ggtctaatag ccaaagcaga cggcggtata
    42601 ttgtttttag atgagatcca ccgtttaccg ccggaagggc aggaaatgct gtttactttc
    42661 attgataaag gtatttaccg tccgcttgga gaaagtgcac aagtacatga agcatctgtt
    42721 cagatcattg gggcgacgac tgaatcttca gaaagtttct tatctacgtt caatcgacgg
    42781 attcctatgg caatcacctt gccgaatctt gcttcacgtt cactggatga gcgttatgaa
    42841 atcatctctc tttttatcaa acaagaagcg aatcgtttga atcaacgtat cgatatcgaa
    42901 aaagaagcga ttcttgcctt catgctttat gatgcggaag gaaatatcgg tcaagtgaaa
    42961 cgagacttga aactagtctg tgcaaaatct tttttacatt accgtactca tcatgagaaa
    43021 aagctaatca ttcgaaaaga agaactttcc cttcaagtac aaaaaggatt actgaaaatc
    43081 aaggaaatac cggaacgtct cgaccgattc atggacagca aaagtcagta tttgacattt
    43141 gaaccaggat ttgctgatgt tgtctggtca caagatccag aacgaaacat gcaggtctat
    43201 aacgatattg aggaaaaagt cacttctctt tccgaaaccg gtgtggagaa cattgatcta
    43261 gagaccctca tttcaaaaga tgtggatgct tatttccaga catatgtcaa agaattgact
    43321 aaaagttcga ttcccaaaga tcttttgcca gatgaaatct ggcggttaac caatcaattg
    43381 tatgatgtgg ctgaaaaacg gttagaccgt atttataatg aaaaagctcg ttttgctttt
    43441 gctttgcatc tgcaaagtac attggatcgt gtgagagaag gtcatatgat cgtccaccca
    43501 gatttgaata acgtacggaa aaattttaag agggaattcc aggtagcaat cgatctttca
    43561 acgatcattg aagaagaaga acaagttgag attccttttg atgaaatcgg ctttattagt
    43621 atgtttcttt ctatcaatct aggagaaagt gagcctgtta aagaaaacaa agtagatgtt
    43681 ctcatattga tgcacggcag acagactgct tcaagcatgt tggagatggc acaagaacta
    43741 ttaggaacaa aagtagggaa agcttttaat atgccactgg ttatggaagt tcaaacaatg
    43801 tatgaagaag tgttacaata tgtcaaaaac tatcaagagc atttgacgaa tggcctactc
    43861 ttgttaacag atatgggatc attaaacacc ttcagtgatt tgatttatga agagactggc
    43921 attcggacga aagctatcac gatgacaagt accatgattg tgatagaagc gatacggatg
    43981 gcaagtgttg gaagaagctt agaagatatt tatcaaaata tccagctttc ctttgaatcg
    44041 atcgtacgtg atcagttcaa agcggaaaag tctgaaactt tacagcgtaa aaaagccgta
    44101 atcgtgacat gctttactgg tgaaggagta gctgccaaat tatatcagcg tattatgcca
    44161 gtgattaatc aaaataaggt agaactgatc cagatgcagt ttttagaacg tgaatcattc
    44221 aaaaaacaca tcgatgcctt attggaagaa tatgagatca aagcaattgc gggaacagtt
    44281 gatgttgatt atcaaaatat cccatttttt tcagcctatg acgtttttga tgatgaaaaa
    44341 ctaaatattt taaagcgtat agctgatgat gagatcccga cagctaaaat tgtcgattca
    44401 cttgctggat cattaagcga tgtcttttct attgatgaac tgatccgttc attgcaaaag
    44461 acagttcagc agatccagac cgatttgtcg attatcgtgg aacctggagt agatactgga
    44521 atcgttatcc atttagcctt catgttagac ggattgatca aacaagaaag ccatcggcaa
    44581 tttgagaaac tgtctatttt ctcaaaaatt tatcgtttgg aaatggatat cgttcgggca
    44641 aacttgatgg cactagaacg aaaatatcag gtaaaaattc cagaagatga tatcgcattt
    44701 cttacacaaa tgtttcttga aaataaaata aaaaaatgaa cacactaatc atactgttta
    44761 cacactaaac atctgtgtgc gcactataaa aaagagctaa aaagcatgaa aacgctattt
    44821 cagctctttt ttttattggc atgcttcttg cgttatataa aagtgtaaaa aaataaaagg
    44881 agtgttaaaa atggcaaaaa aaacaatcat gttagtttgt tcagcaggga tgagtacgag
    44941 tttattggtc acaaaaatgc aaaaagcagc agaagaaaaa gggatggaag ccgatatttt
    45001 tgcggtctct gcctcagatg cagataataa tttagaatct aagaatgtcg atgtattatt
    45061 attaggtcct caagtacgtt tcatgaaagc tcaatttgaa caaaaacttg cgcctaaagg
    45121 tattccatta gatgtcatca atatgcaaga ctatggcatg atgaacggag aaaaagttct
    45181 tgcacaagca gaaaatctaa tgaaataaat caagtatgca gttgggggta taacaacgtg
    45241 gaagatcaac aaaatctaga agccatcatg gggttaatca tgtttggcgg taatgcaaag
    45301 agcgatgcaa tggaagcgat tgcggctgct aaaatcggtg attttgagtt agcggatagg
    45361 aaaatcgctg atgcagaaga atcacttata caagcgcatc atgcacaaac agacatgttg
    45421 acacaagaag cacaaggaaa tcatatgcaa gtgacattat tgactgttca cagtcaagat
    45481 cacttaatga catctattgc gtttactgat ttagcaaaag aaatcatcga actttatcgt
    45541 cgcgtataca gcgaataaat acaacttctt ttttgaacgg aagaagaaaa atttttgaac
    45601 ggatttttta ttttgttata aggagaactc tctttatata aaaaacttat aggaggaagt
    45661 aaaaaatgaa cggactatca agttggatgg agaaatacat cctgccggtt gccgcaaaaa
    45721 tcggagcgca aaaacattta gttgctttgc gtgatgcttt tatcggcaca ctgcccgcaa
    45781 caatggcggg atcagtcgct gtaatgatca atgcaattat tcgtgattta ccgcaacagt
    45841 ttaacagtac ctatgctgac agtttagcag cagacaaagg aatctttgcc gtattgaatg
    45901 tcatcatcgg aatcaatggt tttgtctgga acggtacact agcaatcgcc ggattgatct
    45961 ttgccttttc ttgggggtat aatcttgccc gagcttatgg agtaaatgat ctagctgggg
    46021 ggatcgttgg tttagctacc ttgattcaag gtatttcctt tggtccagca ttatcagcag
    46081 cattagatgt gaatgttcct tcaaatgtcg cagatgcaat caatagttct gagattggtg
    46141 caacgattgc agatggcaca ctgtcagttg gattatgggg ttggctaaaa ctagatcatt
    46201 tgaatggaaa cgcttatttt acagttatga tcatgggagc tatttcagtc attatttttt
    46261 gtaaattgat gcttgccaac attacgatca aaatgcctga ttcagtacca ccagcagtat
    46321 ctaaagcatt tgcagccatt ttaccagcga cgatcgcttt atacgtcatt gctattatca
    46381 attatatcgt aggtcgtgta gctgatgggc aactgatcat tgatttggtg caaaaatata
    46441 ttgcagaacc attcctagga ttatctcaag ggttgggagc agtattgatc gtcacagtat
    46501 ttgttcaagt attctggttc tttggtattc atggaccaaa tgtattggca ccagtgctag
    46561 agggaatctg gggacaagca caactaatca atattgatat tttccaaaaa ggttataacg
    46621 gaaaaactgg tacaccagcc gtgttagatg caatcgaaga tggaaaagct tatatgtggg
    46681 tccgcggatc gttcgatgct tttgcatggt ttggcggatc aggcggaacg atcgtcttac
    46741 tgatagctat cttgattttc tctaaacgtg cagattatct aacagtagct aaattatcca
    46801 ttgggcctgg tatcttcaat atcaacgaac cagtgatgtt tggtctgcca atcgtattga
    46861 atgcaatcat gtttatccca ttcttgattg ctccagtagt agcaacagca attggatgga
    46921 cagctactta tcttggccta gtcgctccgg tatcgcagca agtcacatgg gtagtaccgc
    46981 cgttcttatt gtcattctta gcaacaggag cggattggcg ggcaccgatc gtaacattag
    47041 tatgtatggt cgtgactttc ttgatttggg caccatttgt catctctgca aacaaaatgg
    47101 accctgccgc aggcgaacaa caataagatg aacgtgagga gcgggacgct ttaagtttcg
    47161 ttcctcataa tgaattttct aggaggaact gaaatgatta caattgccag tgcaatgcaa
    47221 caagatgaaa tcaaagaatt gttagaagga tacaatgaag aaggaatgac ttttacattt
    47281 aaagaaaaac aaggaatcaa gctgttcttt gaaacaagtg cagaagatcc ggaagttgcg
    47341 gctaaaaaag caaaggaact aatcaaagca cagccttggg gaacagtcct ttattttcaa
    47401 tcaacagctg tttagaaaat ggtttaaaaa gataggatgg ttgagatgat aaaaaacggt
    47461 ttatttttat gtagtattgg ttctttgatc gtgttgtata gtttgaatcc acattcgcaa
    47521 aggtatgatt tgtatagtat ggtcacaggt ctttttctaa caggattagg aatctatttc
    47581 ttcatgaagg ggaaaaaaag agaagaagca aaggagaaaa ataactaatg gaaatcacga
    47641 aaaaattaaa tattccagca tcgttttttt acgataaagt tatggactct gtccttttcg
    47701 atgtacgtaa agcgaccggc aaatcagtaa ctagaaaaca gctgaaaaat ttggagtacg
    47761 tcaaacaatt ctcgcaaaat aaccgggctc gcataaaaat cgaagaagtc attgaaaacc
    47821 agtcttataa gtttcgtaca tcgacaacga agaatgaatt cgtcgttcat tatcaaatca
    47881 aaccattgga cgattcgacc tgtgaggttc attacacaga aaaaatggag tcttatggca
    47941 tgcttcaaaa gttgaatgat atgcttttag gaacaatctt gatgtatttt aaacggagac
    48001 gtttcaaaaa aatgctagat atgatcgaag caacgtatta aatcaatgaa acatggtact
    48061 atttagttat tgaaaaatga agtaagctag aaggaatttt tcataggaag atagatcttt
    48121 cctgcgaatc ctcactagct tttttgtagg aaggggcagc aaaatgacaa acaaagtaag
    48181 agagctaggt gtatcttcga ttgaggaaat gtttgattta gccacttatg catttaatgg
    48241 ggcagataca cctgaaaggc gagaacgttt tcgtacactt gcggagaatt cttggaatta
    48301 cggatttttt gatgaggagg atcggctaac aagtcaagtc atggcgaccc cttttccagt
    48361 gaatttttac ggacaagagt acctaatggc cggcattggc tatgttgctt cttatccaga
    48421 agcaagggga caaggcggga tcaatcagat catggaaaag atccttgaag attgccgtga
    48481 tcgtaaagta agcttatctt atctggcgcc attctcctat cccttctatc ggcgctatgg
    48541 ctatgaacaa tcatttgata aaatcagtta tcaactaaac agtcgtgatg tgccgtttat
    48601 caaaaaaaaa tctggaaaaa taaagcgtat ggattttgaa gatgcaaaag ctgcaatcag
    48661 aagaatttat gaacagatgc cggaaaacca acgagctggt ctgaagcgcg aagactggtg
    48721 gtatacgtat aaattcaagc aaaaaggcaa ttaccagttt gctttgcatt ttgatgataa
    48781 tgaggaagca acgggatata tcgtttatca gcttgcaacg tcttccttta ttattgcgga
    48841 gtggggattt ttggatcatg atgctttttg cagccttgtt cgcttcgtaa gttctcacaa
    48901 tggtgctttt gaaacatttg aatattcatg cggctacggc ggtaatgatc aaaattatct
    48961 attagaaaat ccatttgctt ctgtaatgat cacaccttat atgatggcga ggatcgtaga
    49021 tatttctttg tttttggaaa attatccatt taaaaagaga caagctgcat ttgccctaca
    49081 aatagaagaa gatcattatg cgaaatggaa tgaaggaatc gtggaagtaa caatcgaaaa
    49141 tggaaaaaat catctctcaa aagtagaaca aacaaaactc ccaatcgttc gaggaagtat
    49201 ccaacatatc acgcagctat tattagggta tcgtaaagtg gaagagttgg tattccaaga
    49261 aagaatacag gtgacaaaag aatatgaaga aacgttaagc tcaatcttgc cacagcaaca
    49321 gccaattctt aatgactatt tttgataaaa aacgggtgat gacaatattt ttgtcaccac
    49381 ccttttgttt ttcatttggc atttgaagga aaatgttaaa gtaaatcctc ttttttcgta
    49441 aatttgaatt ttttgttttc ttttgtttta gggttttctt ttttgtggtc ttggattgct
    49501 tctttcgtaa tcttttcccg atttttttta gatgaatcta agcgttctgc gtatactttt
    49561 tcttttggct tatcattcat tggaaaggac ctccctacat tatttcattc tacctctagt
    49621 ttatcatctg ttaaggacta gtggaaacgt tttgcctaac ttataagctg atttttttag
    49681 cagataagct tgcaagtaaa aaacaaacaa gctacaattg atttattgaa attgttcctg
    49741 tagctcagta ggatagagca atcgcctcct aagcgatagg tcgctggttc aattccagtc
    49801 aggaacgtat aaataacccc tgtatccttt gcggtacagg ggtttgtttt gtatttgtgc
    49861 caaaaatgtg ccaaactagt tatcattttt atataaacta tcgaacacag tattgatttt
    49921 ttctttatcc tgatcttcaa gctctcgaac aatatgaaga taagtagaca ttgtagtttc
    49981 taaactgcta tgtcctaaac gtttcgatac gctaagtata tttactcctt gataaagtaa
    50041 aatagatgca tgtgtatgcc ttagtccatg caaagtaaat tgcttttcaa tccctaattc
    50101 ttttaatttt ttgcgcaaat atttgctgac ggcgtttgat gaaactaatc cattttttaa
    50161 gttgaaaaaa acaaaattat gagggttttt gatttcaaaa ttctcgaata attctttttg
    50221 attgatttta aactttttta agagatcaat cgtatgttta tcaatggaaa ttttcctatt
    50281 tgaagtttcg ttttttgttt ttccccattc atttaattta taattccatg ttttattaat
    50341 agtgatgatt tgatcttcga aatcgatatc ttcccatgtt aatcctagaa gttcagcaaa
    50401 tcgcattcca gtggcaccag caactaacac gagcatagga gaagagtact gcgcagaaag
    50461 gttttcttct acgagtttca ttaaagattt aaattgatca taatctaaat atttatcttc
    50521 ttttggcttc aatgaatctt ttcctttgat tactgctttt ctagttggat caaacggaat
    50581 taatccttct tctacggcat ctttcaacga cgctctaata tggttattaa acttaataac
    50641 ggtagatttt acatggtctt tagcatactt atttaaaaag cgttgatatc ccactctatc
    50701 taaatcagaa atcaataccg ctggcatata tttctttatg ttcattaacg tatcttcgta
    50761 ttttctataa gtgataggag atactgttcc ttctttataa agttgcatcc aatcctcaaa
    50821 gtaatctgat aataatagat ttttgcgatc ccctttaagg cctttgttca agttatattc
    50881 taattcgttg gcggcatctt ttgcttctcc ttttgtctta aatcctgatt ttcttatctt
    50941 cgtgtatttt ccgtcatctt ttttgtatga aatttcgtat tgccaactat ttccacgttt
    51001 gactaatctt gccataattg aatcagctct ctttctctga tacaatagga actataaaga
    51061 agcccattgt ttgggtttta ttattttttg cacatccttt ttgcttgccg gcgcaaggat
    51121 gtgctatttg tcgttttaat ggtataattg gatgtgtatt agatcatcca atcagaggtg
    51181 tttattatga ttaaagtgat ttttaaaaga ataactgaac ttccagagtt tagattattt
    51241 gttgattatt ggtatgtctg gttttttatt gttgcattgc tgataggtct agatgtcata
    51301 ttagaaagaa aacttaagta agagttgagt taataaattg aattcctaaa tgagatattt
    51361 tgtagcccat attttgtttg ccgacatcac ctaatactat ggagctaatc gttttttcta
    51421 acagaccaaa atcagataat ctatttaagc taccatctat tagctcttgt gaatagccag
    51481 acatgctgat atttccagtg aaattttcgt ttccacgact cattaagcat gctaacaatt
    51541 gaatctcaat cgatgttaat tgattcagta caagaagata atactcctcg ttatcccatg
    51601 aagcgctgtt aattcgaagt aaacaattct tataaagatt tttatacata tctattttat
    51661 tttgtgcctt tgatttttct acctcgtcat ttatcccttc gaatattcca atgagttggt
    51721 ccttgttctc taagttgaaa acatcttctg gaatttgatc gcgaatgttt tctaatgatt
    51781 cgtttaaatt tttgtagaat ttctcgatgc gtttgaaacg cttctcgttt ttagacccaa
    51841 aataaagtga ctgcacaacg ccaccaatat aaggaattgc tccaataccg ccttcaacta
    51901 ttaattcaag atattctttt ttggttagtt tttcattgct attatccata gttacctcct
    51961 attttgtcat ttcctttaca agcattgtga ctcctgatgg cactcttttg tataggtttt
    52021 attattgtgc acaatctaac tcttagtggg gcgtggttca tttatttttt acttacttta
    52081 ctattaatca tatcccattg agcataggat ttttctatgt tcgatcctct tgaactaatt
    52141 tctcctgtaa aagttacttt atcgcccttt gtaaaggtat cagcattgtt taagtccttc
    52201 gcaaaaatta catatgaaac tttaggtgtt gcagaaatat cattccaact tttatcatcg
    52261 tactctttgt ctgctataat ggctattcta gtagtcattg attcgataac agttccttca
    52321 aaagtatatg ttttaccact aatatattta gtaaaagctg tattttgctc agtagctgga
    52381 gtaatagaat aataactatc taagaaagca ccccagtcat gattatttgt ctctaaaaat
    52441 tcttcaaatt gagttaggct tttattgctg ctgttagatg tagtagtttg agtatcagat
    52501 gatgagcttt cctgtttgtt attgtcattt gcctcgtttg atgaggaaag cgagaaacct
    52561 acggtagtaa aaataatccc gataataagg agaatcatag gtgttttctt atttgttttt
    52621 ttgataaatc ttacaattaa catgattaaa cctataataa ataaaacaat accagtaaaa
    52681 ccaaatatac cgtccattaa tagatcctct ttctcttttg atattgaata ttataaacca
    52741 agcaattctt ttttcttaaa atcgaattct tcttgattaa taatcccttc atctaacaac
    52801 tctttatact ttttaatttc atctgcactt gaaatttgtg tttctttgga attattatct
    52861 aatatagatt gttgcttctc tatatatttt tttaaatttt ccatttcatt ccaatatttt
    52921 tttgtaaaca taacggtgtt ttcatctttc gtggccgcta atatacctcc gcgactttcg
    52981 tttccgccta gcaaggtaaa ttgtatataa ccattactca tacctggttt ttttaattgt
    53041 acggctgata tatttttaaa ggggatagtt ttttctcctt taataccttg attaactaaa
    53101 tttataaatc cttttctaat aattgaaata gaatcatcag ttactttaat caaggttttt
    53161 cctggagatt ttattaaaat ctctttttcc attttttctt cctcatttct gtgatatgat
    53221 tttttttgta gaagctcata tatgaggaaa gagcccgtgt tgcagcacgg gcttttttaa
    53281 tgttttgctg aaatcggttt ttttaataat tcttgatgta ttcatacata ttgccttgcg
    53341 taagaatatt ttttcttaaa atagcattgg cagacagcat aacaagtgta tctgagctta
    53401 ttctgaatag aataatactc cataaatttt tcgagattaa actgagattc atcagtcagt
    53461 tcgttctcaa tatagatatt taataaaatt agaatagcta ttttatctgc ttctgtttca
    53521 aattttgagt gaaaagttgt agaagtatcg tacaaaactg aaaattcaaa atgagaggcg
    53581 ctgaaatgtg caagttcatg agataaatga aaggcttctg cagtttcacc gtatagattt
    53641 tcattcaaaa aaatgattct gggttttgga tagtagaaac caggctcttt catctccata
    53701 taaactactt tcaaattgta ttcgctcaac atttctttca atttcaaata catacaaacc
    53761 atcactccaa ctattcattt tcctctaaag ctttagcaat tgcaatcgct ttacgcattg
    53821 tctccttaga tatttctttt ccatcaaaag aaaaaacagt atcgtcttct gataaatcca
    53881 catgtttagg ggtttctctt tcttctctac ctagaaggta gtctacagag acatcgaaat
    53941 agtcagcaat ccgacttaat tcatctgaat taggagtatt atttttccac tttgctagat
    54001 aaccgttaga atatccaaaa ttaatttcta actgccgtat agatatcttt ttcctcttcg
    54061 ccaagtcttt tattatttca taggtattca tcgataaaac aacctttcta aatgtttaca
    54121 aaaaaagttt agaaaaatac gcagaaataa tttgactaat tctgagtaat gagctatact
    54181 atatcttgta aacagattta acaactaaaa agacaacaaa aaacactatt gatatgtaaa
    54241 tgcagaccgc caagaaagct ttaaaatcaa tgtttttatg tcttatttaa ttatgctctt
    54301 agtatagagt attactcaga tactgtcaat tgaatttaga aaaaagttgt taaatttgtt
    54361 tacgaatata aaagaaagga atgagaaata tgaacacacc gcaaattttt aatttcgaac
    54421 aaaacgaagt tcggacaatt ttagtaaatg atgaaccata ttttgtaggc aaagacgttg
    54481 cgagtgtttt gggttattca aacactaaag atgctttgtc gcggcatgta gatttggaag
    54541 ataagatggg gtcgcgaatc acgacctcag gtcaatcaag agagatgaca atcatcaacg
    54601 aatctggttt gtacagttta atcttaaaat caaaacttcc ctctgccaaa aaatttaaac
    54661 gttgggtaac aagtgaagtg ttgccagcaa ttagaaaaca tggaggttat ctaactccag
    54721 aaaaagtaga agaagctttg cttaatccag atacaatcat tcaattagca actcaactaa
    54781 aagaagaaag aactggaaga ttaatcgcag aacaaaagat tgcagagtac gaacctaaaa
    54841 tctcctattt agatagcata ttatcttcta cagattcagt aacaattagt cagattgcag
    54901 cagattatgg gatgtctcca caacagatga ataaattact tcataaacta ggtattcaga
    54961 aaaaagtcgg taaccaatgg ttattgtgca aaaaacacat gaaccaagga tacacaaaat
    55021 ctcatacaac tgagatcccg aaagccgatg gtggcactaa aattgtaatg aataccaaat
    55081 ggacacagaa agggcgtcta tttatctacg aattactaaa aaaagaagga tattaccctc
    55141 aaatggattt agaggaaatt ggttagaaag gagttttagt atgactgaca ttgcagaaat
    55201 cactcaacga gatagagaaa aaatcaaaga atatgtcgaa agttcaaagt tcttaactta
    55261 caccatgctt gctgaaagat ttggaattag caaaagctac ttatctttaa ttttaaacgg
    55321 taaaaagact tctgcagaag caaacagaat tatagattcg attatcacta tgtacgaatt
    55381 gtaaagggag gaacagctaa tgcaatatct agaagcaaaa atcccaattc cagaaggcta
    55441 tgtaattatc tcccaagtgg attatgagga gttaaaaaaa gctgatgata ctggtagatg
    55501 gatgacgttg ccagaagtgc tagaacggat taacagaaaa tatgattggt ttacttctag
    55561 agttttaaag aacccaagat atagaaatat tatcgatatc gagaaaaaca aaaatggatt
    55621 tgtctattat ccagttgaag gaagagacac atatctattt ttaagaagta aaacacttga
    55681 atttttagaa acaaattttt cggaaatctt aaggaggcaa gcggatggga aaatttaata
    55741 gagcgctagt gttcagcgca ccgctaatca tctacgcttt aggactttgg ggaagcaggc
    55801 aagcgttgat aggaacgatt gtttacatgg tttggatttt tatggggctt gatgaagctg
    55861 aagctgagta cagagcgaaa aagccaaccg agggggctga ctaaaaatga atagaaaaga
    55921 gaaactagaa tgtatattac tattactcag tttaattctt tcactaattt ctctattggg
    55981 aagtttgtat ttttgatatc aacaattttg tggatttggg ttctatttag agtaaatatc
    56041 atttttgttt ggtgattaag gagtttatta aaattaattt tccctacttc aaatgcaagg
    56101 taacaagata tagcactttt aggaggaata tttagcggta cagcttcaga gtatattcta
    56161 ttatcatcga ctgatcctcc tttagcaatt aatttcttaa atggagtagc tgaccatctg
    56221 cggtttaagt tagcggatga aagttctaaa ttaactaaca tagctggttc tgttgaatag
    56281 ttagaaatga ttacttttgt ataaatcata tctgcagcga agtaagaagc attaagttca
    56341 acttctagtt gagggcgcat tccttttatt tttatccctg ttaaaaacgt actcaatata
    56401 aaacttatta ttgacatcca ttgaaaaatt gttaagtgaa aaaaattcaa aataaacacc
    56461 accagttttt aactaaatta taccaaaaag gagagaagaa ataatgcaag aattagtaat
    56521 tttgaaaaat aaagaagctg tgactacgag cttacaagtg gcagaaagct tcgagaaaaa
    56581 acatcaacat gttttaagag atattgatgc actaaaaaaa gatgtgtcca attttggaca
    56641 gatgtttgta gaaggtaatg aaccagattc atatggcaga aatcgacgag ttttcttcat
    56701 tagtagagat ggatttttct tgctggctat ggggtttaca ggaaagaaag ctatctactt
    56761 caaacaaaaa tacattgaag cattcaacga aatggaagat gttattcgca agaatactgt
    56821 tcctcaaaca attgaagata tgatgatcta tcaattagaa gaaatgaaag atgttaaaaa
    56881 agatgtttcc atgcttaaag atactatgcg aattagcgga caacaagagt ttgaaattaa
    56941 gcaaaaagga aatatgaaag ttatgggagt tctaggggga aaagaaagcc gagcttatga
    57001 agaaatcagc aaaaaagtat tctcaaaatt ttggtctgaa tttaaacgta ccttttcaat
    57061 cccaagatat ggcgagttac ctcgtaagag attcgatgat gctgtttcat ttattgaaat
    57121 gtggttgcca gaaactgcga tccgtatgga aattgatcaa ctgaacagac aacagagact
    57181 ttttggtgat gacaatgaat agagctgaag cgctaagaat agggacggca attgctaatt
    57241 gctggtggaa atactataaa ccaatcatcc taagccaaca acatattgac aagcaaaaag
    57301 catggcaaca aataaaaaag tgactccgcc ggcaagcaaa gagtcacaaa gaaaacacat
    57361 cataaggaga ttttagcata tggaaaaaga actttccact ctagatcaat atttgattga
    57421 tcctgattgg ggcaagccga aaattgagga aacaagtggt cgaaaaatca gacgaaatct
    57481 tttgacgaat gaagaactag cttgggatca agatgattta ggcaaccatg taactatttg
    57541 ggatcatgtt tatcttatcc atctatcgaa gcattcgaat aaacctgaat atatttacgt
    57601 catcgaagat ggcttgattg atgcgctaga agagtacgac agagataact tgattgatat
    57661 ctcttattac ggaccaggta agaaatacat tgctgaaatg gaggcagaat ttgatgagtg
    57721 aaatcaaagg gacaacgaac tttgaaaaac tttttagtcg taagttaaat aaaattctca
    57781 agaaaaaagg aaattttgat tatttatctt gggctcacgc gtgggagatt atgaaaaaga
    57841 atgatccaca ggcaacggta actattaatg agtacaaaca ctacagggtt gtttctggaa
    57901 ctcatcaaga ctttcttgtt gaggaatata aaccttttct tatggatgaa actgggactt
    57961 atgtatctgt ctcagtaacg gttaaaggac acacggaaac cgaattattt cctgttttag
    58021 attatcgaaa ccaaccagtt gttaaaccaa atgcaatgca aatcaataac tcattgaagc
    58081 gatgctttgt gaaagcattg gctctacacg gactgggatt atatgtattt caaggggaag
    58141 atattccaac accacctaga atcgatacaa agaaattaaa catgctagag acgattctag
    58201 aagctttcaa tgagcagatg ggtaaagata tgaccaaaac cttaatcgaa tatgttaatg
    58261 agcagacaga taaattaggg ctcttagctg ataacgttga aactattgaa cagttaagct
    58321 atgagcaatg tgccttgatg gagcgagcaa tagcagctaa gagaaaagaa ttagataaga
    58381 agtgatatga gtgtttaaac cattaatcga ttcatattca gcggttctga aaaagttcaa
    58441 aggaaaagac ataagcgcaa ccatcaatga ggaagtgaac attgatcgac taaagacgat
    58501 gtatgacggc tacgatggtg atcgagtcat tgaaattcgt tttattgatc ctagacgttt
    58561 caccgtacag caacgaaact tcatctatgc gctgataggc gatattttta tcgatacagg
    58621 catgccaacg gacttctgga aggaattctt ctactttcgt tttgaaggtg tcacagggcg
    58681 caaaataagc ctgaaagacg aatcgaatac aactgtgagt gatgccaatg tcttagcaaa
    58741 tatcatctta gatttcatct ttgaacatca tattcctttc aaagaaggct atgagatttt
    58801 acctgcgaat caagaatatt acttctacaa atgcatcaca aaaagagtct gctgcatctg
    58861 tggcaaaaca ggagctgaca tcgatcactt tgacaaagcg ctaggaagac gaaagcgcaa
    58921 agaagttgat catgcagagt acacatttgc agcactctgc agaatccatc acacagagaa
    58981 gcacaaaata ggtgtgatta atttcaaaaa taaatatcaa atcaaaggga tcaaattaaa
    59041 ccagaaaaca atcaaaaagt taaatattgg agggtaaaaa tgacagaaca tcgaagttat
    59101 tatgcgatta taccagccaa cgtaaggtac gacaaaagac ttaaaccaaa tactaagttg
    59161 ttatacggag agataacggc cttgtgtaat gaaagaggct tttgttgggc aggcaatgag
    59221 tactttgcag atttatatgg tgtgaataaa gagaccatat cgcgatgggt aagtgatttg
    59281 attaagtttg gatacttgaa tcgggaaatc atttacaaag agggtaccaa tcaaataatc
    59341 aataggtacc tacgaattaa tcaataccct attgacgaaa aacgcaatac ccctattgac
    59401 gaaaaagtca aagataataa tacatctatt aataatacat ttaataatac aaaagaatat
    59461 ataagagagt taccgccttc gaaaaaatcg aaggctaagc ccgtccgtca taaatacgga
    59521 gagtataaaa atgttctttt gtcagatgag cagatggaga aactcaaaac agaattccct
    59581 aatgattacc aagagcgaat cgaacgactg tcagagtatt gtgaatcatc tggtaagact
    59641 tataaaaact atttggcaac tattcgaagt tgggcaagga aagaaaaaag tgaacctaag
    59701 aacgcaagca gtggatacaa gcgcacagga agacgagaga agcttcctga atgggcaatc
    59761 gaccaagaag cctatctcaa gaaaaaagcg ctagaacgag ctaatagaca atcaaaagca
    59821 ccattctaag aggtggaaaa atgaagatcg attatctaga actaattaat gaaatagcga
    59881 attataaaaa gggcgaggaa ttagacgtcc tgagagacgt atatgatcaa ctcgaagaag
    59941 ctggaattga aggaattaag aatgatcgtt cgagttggag taaactcaga tactatttcg
    60001 cactctatat cgatggaacg caattaagaa atttagcata taccaaatta ctattcattg
    60061 attgtgttaa aggcttgcaa aaacatctta atgaacttga gcaggtgtaa acaagatgga
    60121 cctaaagaca tttacagcac agatcgaatt aatgcatcaa gaagctttaa gacaaagtgt
    60181 gtcgtacgaa gacaagtggc tcaacacatt tcatggcgga cgtgagagcg cacttgatca
    60241 agtactcaaa ttactgaaag gagaatgtcg ggatggataa gaaagcggca atgcagcgaa
    60301 ttatcgaatt gacttattca gaagattggc aggaagataa aaaaatagtt gcagaagtcc
    60361 aaaagctcgg taaatcaatg tggactgaaa agcccaaacg gagaacgccg agaaagattg
    60421 caatctggca tggtgatcga attctagtaa cgggtaccgc taaacagtta tctgaaatta
    60481 ctggtctgag caaaaatatt atttgggata gagctaggag cttatggatt gattcaaaag
    60541 gaagacagtt taggtatgtg gaggagaaat aatggacgaa ctaatcgcga aagtagagca
    60601 gtgggcaaaa gataagggat tggatcaagc ggatttcagc aagcaaatgt taaaaacggt
    60661 cgaagaaatc ggggaagttg ccgcttctct agctagaaaa gatgaacatg gtttaagaga
    60721 cggaattggc gatgtagtag taaccttgat catcttggca atgcaaaatg atatggattt
    60781 atacgagtgc ttggattttg cttatgacga aatcaaaggt cggactggaa agatggtcaa
    60841 tggtgttttc gttaagtcca gtgacctgaa ataattccat taatggaaga aataactgaa
    60901 taggaggata gacatgattg atgcaaaaca agtgcaaaaa cagaaagatg gaatgttgat
    60961 gtttgaagca tatgttctac catttcttaa tcaatttgaa gttttggaat gctctgccag
    61021 cggagaagaa ttggagtatg ttgtaattcg tgaaaccaaa gaaaacgttc agaagctaaa
    61081 cgaatttctt tgcactatta actgttggga tatgatagct ccaggatttt tatgtccagc
    61141 tatgggagaa tttttggaat attgtcgtct tgaagatgca ggcactttgg atttagctta
    61201 tctggtatac aactacctaa acatcaacac agatcatttg tggtttggca ctgccgaaag
    61261 aaaatgggta gtccgctaac caccaatatc aatgaaaaaa ggcggtttcc tgaaagtgga
    61321 attgccgcca ttgctgtaag gttctttacg cgactcaagg tcacagaaat ataaatgcaa
    61381 atctcttttg aagtgatcca aagctctcgg aaaatggaag ttttttgttt caaagaataa
    61441 atgagatttg cgtcaagaac ctgagagtta tttccaaaaa agcttccaaa gaaccgaatg
    61501 agctaaggac atcatgtgta aacacataat atagctctcc tttcacggct aatcataaca
    61561 tgaaaaatat tcgatgtcag taggaaaaaa ggtgaattat gaaaagaata ttaaattatc
    61621 ccggcagtaa cagattctgc aattaaactc cgaagctgat gtatcagtat caactgtaga
    61681 atattatgag cgtggagaaa gtcaagcagt cacaaatgta aaaatcgata acgtcaacgg
    61741 tcttatctgt ttagatgaag gcgatagtat gaatgaaatt gctgcagacc atgaattatc
    61801 agaaactgct ttaattgatc aaatcgaatt agctagacaa tactttgttc catatgcaga
    61861 tacctggtcc aagcataaga atgacatcat ttttccagag gaacaatgag agcaactgat
    61921 ccagtaatta tccttgagga agccaaattt atttggactc acgaagagat agagcaagca
    61981 cgcttgctct tttctcaagg agttaagccg agcaaagtag ctgaaataat gggtcaaaag
    62041 attcttgatg tcggattgct tttgctccat ctagcagaaa aaaatttgat ttgaggtgaa
    62101 aatgatgatt caacttgcag gcatccaaac agggaaaatt tatttttctg gagaaagcaa
    62161 aagcgaagcc aaccaatggc tattgaaaac ttacacgaac aataagaagc taaggaaaaa
    62221 atatcctgat ttgttgctaa aggatgatca gattatgccg gaaccgatga ttttgacccg
    62281 taaggaggga agttgaaact aaaaaaccag ccgtgtgggc tggagttgct atttcttttt
    62341 aataatgagt ttttctaaat ttaattcatt ctcacgagtt tgcgtccaat aatcagaata
    62401 atattttaat tgtttaagag taggaatgtc gtcttcggta aaattagaaa ataattctgg
    62461 agaattatct ttttttaatt gttctaatcc tgattcttta aaacgttgtt caacgagttt
    62521 tactaaattg ttgatattca tgataaatca cctttttaaa tttaatttcg atttgattaa
    62581 tcgatacaag tattatatca aataaaaaag ctgatttagg gggtcttaca aaaacactaa
    62641 aattttttca aaaagaggag gaacggtggt gaaagtcaga gaacaattca agatagtgag
    62701 cgacgaagat aatgtttaca aaataaagat cgttaatatt aatgaatatc gagaagcaga
    62761 tcacaaatat ttggttgact tatacatgaa cgataaatat ttgggagaag gattttgtgg
    62821 agattcactt tttgatgatg agcgaatttt gaaggaggaa acagaatgat ccacgaacta
    62881 aaaatactac cagaatattt tgaagcagtg acgagcggac gcaaacaatt cgagatccgc
    62941 aagaatgatc gtgacttcaa agttggtgat cagttaatac tacgtgaata taaaaaatac
    63001 attaaacatg aattacctgg actaacgaga ccaacattta gttacactgg tgactcatac
    63061 aaagcagaga tcacttatat tactgattac atgcagaagt ccggatatgt agtgttgggg
    63121 attaaagggg tgaattaaat gaaagtatac atcttagcta tcacagaggg cacatggatg
    63181 ttcccagtcg gttccggaaa aatctataaa tcaaaaacag ctgcttataa agcatttgaa
    63241 aaatacaaaa aagaaaacgg tggcggcact aacgcaaaga ttctagtggc tgataactgg
    63301 catgaagaag gtgaacgtaa ttgatttacc tgttcatttt cgtggtacta actattttta
    63361 tgctagtaat cttattcaaa aaaagatgag taaagacgaa cgaaaaattc tggccaactt
    63421 ttatttagta ttaaaaatcg aacaaaatgt gttttcggaa aggagaattg tatgggaaaa
    63481 acaaaatcaa agattaagaa gaaaaaacga cgtttggaac aaaaggcaat ccagaatgga
    63541 acggctaaga aaaaataaaa aagctacccc tttcgagata gcagcgcaat actattctac
    63601 cataaggggt ggcgtttgtg agatttcatt ggttaaaaga ttaccaagaa ctagatgagc
    63661 agattcttta cttaaagtgg aatcttaata aaagtaagct tgaattgaat cgatgggtct
    63721 gtggtgattt agcaaacgtc cgcatcgaaa agaattcgag aacttcttct ttagaagaga
    63781 atatccaaaa gatagaaaat gaattggaat tgttgatcga gcaaaaagaa gaaatgttat
    63841 tgctgataga tagcttttct ggtatcgata atcaaattgt taagatgaaa tatgttgatc
    63901 aaatgagctt agaagatatt gctgaatctg ttgggtatag ctcatcgtat gtcagacagc
    63961 gacatgcaga aattagaaag acattgaact ttttagatga gtatgaacac agacaagctg
    64021 accgattgaa aaaagaaaac gaaattgatt tttacaatag cgagaagtac aaagaacaac
    64081 tctctttatt ctaaaattac actgttcact aaatgttcgg tcattgtagc tatgtaaaca
    64141 ttgttagcag catgatattc tattagtgtc aaaaaaatat gaaagagcca agatatccca
    64201 accgttttat taattggtat ctgtggctct tttattcttt taattagtag ttggcataaa
    64261 gttatttcca tttataaatt gatcagctaa atcagcatca taatcagccg cgataaattg
    64321 cgctgctgat ttaataaatg catccatatc atgaacatct ttattagtat gtctacgaac
    64381 atagtgcgtt tcatcattac caatccaagt agcagctttg gctaatcttt ggagtttagg
    64441 aaaatcattc aaataatttt caattgtttt acctaataac atttttttta ttttatcttc
    64501 atcctctgaa tttttagata ttgcataatc tttaattaga aattctagag cttttctata
    64561 accaactcca gcaatttgtt ccaattgctc agatttagct tgtgtggctt gagtataaat
    64621 atcaacaaat gtaggagaaa ctttttcaat attttctggt aaatctattt taatcggcgg
    64681 acggtaataa tctttaatta aaatattttc agaatatcct tcatcttcat taaacgtatt
    64741 tataaattgt aaactataaa atttgttgca ctcatcattt atacactgta ctaatacgcc
    64801 aaagattcta tcattatcga acgcactata tgatgaaacc ccaaaataca catacggagt
    64861 cattatattt ccgcaatgcg gacaactatt tggcaaataa attgtctctg tattttgacg
    64921 atcacgatac ttaatattaa cttcttgaag cattaaaaca cctcgcatct tttttataaa
    64981 tcataccaca aaatatctga taggagagta aacaaatgaa tgattttcat gaagcggtac
    65041 ttagtattga agtagaatca agtttggcta aagtttataa gaaagcaatt gaagcagaga
    65101 atagtccgta cagagaaaat tggaatggta atcatgcaca tgtgcaagtg gagaatgatg
    65161 attacagaac tggaatgaat acgttagtta tttctttatt gtcacacact ctacccaatc
    65221 tgcaggaaac gattgaatgg tatgagcgaa tgggcgcaaa agtaatccgt acaaattaca
    65281 aaggagagaa ttaaaatggc aatgatcaaa attagaacat ccattagtgg aacagagtat
    65341 tgggattcag aaaagaaaag gacagtagtt gttccgaaag atcaagaacc aaattttgaa
    65401 gtaaaagaag aaaaaggaat tttgagtgat ggcaaatcat ttgttgctgt caatggcgaa
    65461 ctcatagctc atagcagtga aattcttgat agcgatggaa acactgctgc taattttgat
    65521 ggagacgaag ctactaatga tcagtccact gaagatacgg atgaactgga caatatgact
    65581 gcaaaagaat tgcgtgcata tgctaagaaa catggtattg atattcctgg tgctatccgt
    65641 gcaaaaggcg atatcataaa tcttattcgt gaagtagaat gaaatactgt cagtttgacg
    65701 gatgcacgaa caaaatagca aagggtatct actgtactga acacaagaga tcaagcagat
    65761 cacgcaagaa gaagcagcaa gcaaagtctg tttatcatca tgagaacaaa ccattctatc
    65821 gaacgcaagc atggaaagat atgcgtcaat ttatttatga aagagaaggt ggtcattgtc
    65881 agcggtgtgg tcagttcata tttggaaaga gagcacacgt ccatcacatt gtaccaatca
    65941 aagacaacga actgcttaag cttgatccaa acaatctcat gctattatgt tcaaaatgtc
    66001 atccaattgt tgaaaacgaa acggaagaca aaaaagtttt tccttcgtat ttcaattgaa
    66061 gcccccctat tcattttcaa aattttttcg cgtggggaga tagggtagcg gggagtcacg
    66121 cgcatcgtta ggtcaaattt ttcaaaaaac aaaggggggt gtatacaaaa atgacgacta
    66181 aagcgcaacg taaagcgatt attgatgaaa aagtaagtgc tgaaaaagct cgtatcttag
    66241 aaataatgaa tttgtctgat ttgtacacca tcactcttga tccattaatc gaatcatact
    66301 tggatatttt tgaaatttac caacacaaat atttattgtg gaaggaaaaa ggatttccgg
    66361 agacgcaaaa attcacgaat aaatcaggag ctactaatca atcaaaacat ccattggcac
    66421 aacaagtaga aacttgggca gataagaaga tgaaagctct agatttatta ggattaacaa
    66481 acaaagcaaa aactggtaga ctaattgctg gaggatcgac cgcaagaaaa gatgaagaaa
    66541 ttacacgccc agaagtaaag ccagtagatg aactagcagc gcacagaaat aaatggcgta
    66601 agaaggcagg tgctgaaaaa tgattgaacc tggtgtaaat tatgctgatt tatttgcaaa
    66661 agaagtaaga aagaaaccta agaagtatcc taagaccgtt cgtttagcaa tagatcgctg
    66721 gtatcagtgg aaaaaaagaa aagatatttg gtttgatgta gatcgcgcga atgaaatgat
    66781 ggattgggta gaatcattta ttgttcacac aaaaggagaa atggtgggaa aaccgtttct
    66841 tttagaaccc tgggaaaaat ttatttattc ttggatttat ggttgggtta aagaaaatga
    66901 aaaaggccaa attgtacgcg ttactcgtga ggcttatgtc cagattccaa aaaagaatgg
    66961 taaaacattg attgctgtcg gttcattagg atatgcaatg tacggagaag gggcgttatc
    67021 agttgattgc tatgcttgcg catctgattt tgctcaagcg caatatgctg ccaaaccttt
    67081 tgcagttaca atcttaaaca atccaatcct acttgaagga actaaaatat ttagggggcc
    67141 aaagggaact gtttctagta ttacttatga ctatattcat gaagatatgg cttactcaaa
    67201 taaatttatt gttcaaacca agaatattga taatatcgag ggatccaatc catattttgt
    67261 attgaacgat gaattgcata aacaggagaa aatggaacag tatgacaatt ttaagtctgc
    67321 tcagatatct ttaccacagc cattgatgtt taatatctca actgctggga aaggttcgtc
    67381 gtctgttgga atgcgtgtat atcgcgaagc aaaagaagtg ttgaaacgtg atgataatga
    67441 ttcaaacttt gttctaatct atgagccaaa taaaaattat gattggacgg atagaaaagt
    67501 ctgggaaatg tgcaatccta actggggaat atcagtcgat ttatctgctt tagaatcggc
    67561 atttaaaaca gcgcaacggt cagctcattc caaagctgaa tttctaacga aacacttgga
    67621 tgtatttgtg aacggcgcgg ataatttctt tgaacaggat caagtagagc catgtttagt
    67681 taccacacaa gaacttggtg atttaagtgg cgaaccatgt tatatcggtt tagatttatc
    67741 acgtacacga gatttgacct gtgtatcttt aaacttccca acatgggatg aagatggtaa
    67801 agcggttctt aaagtaaagc aactttattt tattccgaat gaagatttag agtttcgaga
    67861 aaaagaagat aatgttcctt acagtgattt ggctgaacaa ggtttcgttg aattttgcga
    67921 cggaaaaatg attgatcaag atcagatttt gcagtacata gaggactgca tgaatttata
    67981 tgatattcag caagtgaatt atgatccagc gatgagtgac aaacttgttg agaaattaga
    68041 aaacttagga ttggaatgcg ttgaagttgc tcaatatcct aaagtattga atgctccttt
    68101 tgacgatgtc gaacggttgt tttatgagaa acgaattcaa tttgataatc cattattcct
    68161 ttattgcact ttgaacgttg tagcaattac taacatcaat ggacaaaaag cgccaagtaa
    68221 acgtcaatca aagaaaaaga ttgatgggtt cgtggcgttt ttgtgtggtc ataaggaaac
    68281 gatgaatcaa atgacagata ttgattcaga tgagttagat gattacctaa gttccatcta
    68341 tagataaata gaaaggcggt gaaaaaaatt gaaattacgt gatcggttat cgaatgcagt
    68401 ctattctttt atggaaaaac gtggatatat cgaggatatt tttggacact acacacgtta
    68461 tggtcaaaga tatgtgacgg attcatctat catggaatct tctgatgttt atgaattagt
    68521 tcaagacata tctaatcagg tggcattggc cacaccaatt gttattggtc ccgacggcaa
    68581 cgaagtcaaa gatcatcact tactaaatat tttgaagagt cccaatgatt atttgacagg
    68641 attcgaattt accaaattgg aaacaaatac tttattgatc aatggtgaga cattcccatt
    68701 aacggatagg gatcagcttc atttggcgta cggtgtaaca actaaaatca atgaacgact
    68761 tcaagaagaa tttgaaatga atggtcaaaa aatacctggt caaatgattc gacacattaa
    68821 gaacatcgga actgattcat taaaaggtgc tggaataatt gatcttgcaa gaaacactct
    68881 agaaggcgtt ctgagcgctg aaaaagtttt gacggacaaa tatactaaag gcggtttact
    68941 tgcgttcatg cttaaactag acgcccacat caatccaaat aatagcgccc aaacaaaaat
    69001 tgtcaaagct atattggatc aactggaagg aacgcaaaat gagagtgatc attctgttaa
    69061 gatgattcct ttgggaaaag gatattccat cgagacatta aaaagtcctg ttgatgacgc
    69121 ggcaattttg aattatttag gtgtttacaa aaaagactta ggaaaatttc taggaatcaa
    69181 tgttgatacg tatcaatcgc tgatgaagac agatattgaa aaagcgatga tgtatctgca
    69241 caacaaagca atcaaaccaa tattgaaaaa caagagcgaa cattacaccg ctcttttttt
    69301 tatgcctaat tctggctata gagtggaatg gaaaattaat attttggatt ttgttcctta
    69361 ctcaacaaaa acaaatattg gctacaacat cgttcgtacc gggattacaa gtccagataa
    69421 cgtggcagaa atgcttggtt ttcctaaaca gaatactcca gaaacacaag ctatctatat
    69481 ttcaaatgac ttatctagga ttggccagaa aaatgcaaca gatgattcct taccaacgaa
    69541 tgatcaagac ttgaaaggag gtgatggaaa tgaagaagaa ggaaattcgc acgattgaca
    69601 tcaccaatct ttcaacacgt tccgatgaag aaactcatac gaggaccatt agcggctacg
    69661 ctgctgtatt caacagtcaa acacttttat gggatgactt aagcgaagtg attgttcctg
    69721 gtgcattctc aaaggcaatt agtaattcgg atgttcgttg tttgttcaat cacgattggt
    69781 ccaatgtgct aggacgtact aaaagcggaa cccttcgcct tgaagaagat gaacgtggtt
    69841 tgaaattcga agttgattta ccggacacaa cggtagcaag ggacttagtt aaatctatgg
    69901 aacgaggaga catcaaccaa tgtagttttg gttttgtgcc gactgaagaa acgtgggact
    69961 acaattctga accaatgctt cgaacaatcc atgaagtgga attatacgag gtttctattg
    70021 tgcctttgcc agcatacgaa gatacagaag ctgcattaag aagtcgtgat gaattagaaa
    70081 aaaacgtcga agaaagaaaa aaattaatca aaaaaattaa tcaagcgcta gaagcgtagg
    70141 aggaaaaata catggataaa gaattattga aaaaaatgaa ggcacgtcgt gagcaacgat
    70201 tgactgaatt acgtgaaaaa gttgaatcag gagaattacg cgaagcagat ttagaagccg
    70261 tgaaagaaga aattgacagt gttattgatg aattgaacgg aattaaagac gaattaggcg
    70321 cagattctgg aactgatgaa acagacgaca atacagatga tcaatcgaat agtacggatt
    70381 cagacgaaag ccgttctggt gaagacaacg atcaagaaga agattcagac agtgaagata
    70441 gttcagaaaa tcgttctgga atgattactc aacagcaacg agatggatta cttggatcaa
    70501 ttaagaacgg attggaggca cgtgcaaaaa tgaccaagaa acaaaaagat caacaactac
    70561 gaaaagcatt tgctaatttt gtagctggaa atatttctga agcagaagct cgagctttag
    70621 ggattgaagc tggcaacggt tcagttactg tcccagaagt aattgcatct gaagttatta
    70681 cttatgctca agaagaaaat ttacttcgta aatacggaac agtggtgcga acatcaggag
    70741 atgtcaaata tccaattctt gtgaagaaag cagatgcgaa tgtaaacaag aaagagcgtt
    70801 caactgatat tgctgaaaca gctattcagt ttgatgaaat tttgcttaat cctgccgaat
    70861 tcgatgcttt ggcaacagta actaaaaaat tattaaaaat gtctggtgtt ccagttgaag
    70921 atattgttgt ggaagaattg aaaaaagctt atgtgcgtaa agaaatcaat tatatgttca
    70981 atggtgatga cgctggaaat gaaaatcctg gtgcattagc caaaaaggct gtagcattta
    71041 aaaaaccttt agatctaact gcttcaggtg ctgggcaaaa attatatgat gcattaatcg
    71101 aatttaaaaa tacaccagtg acagaagtga tgaaaaaggg acgctttatt attaatcgag
    71161 ctgctttgac tgccattgaa aaaatgaaaa cagatgatgg atttcctttg ttgcggccat
    71221 tcacacaagc agaaggtgga attggttacc aattagttgg ctatcctgtg gattggacag
    71281 atgcagcaga taaaaagggt gaaccagaca cgccagtttt atattttggc gatttttctg
    71341 catttaaaat tcaagaagtt attggtgcct tggaaattca aaaacttgtt gaaaaattct
    71401 ctggtaaaaa tcaaattgga ttccaaattt acaacttgct agatggtcaa ttggtttatt
    71461 ctccatttga accggcagta tatcgctacg aaattacaaa accagttggt ggttaagatg
    71521 gaagagcaaa ctaaagaatt gtctttagag gaaaaattca aatcacatat tcattttgaa
    71581 gagggcatgg atgattcttt gctctctttt tatttaaata tggcaaaaga ttatgtcaaa
    71641 acagcaactg gtggccaaca agaatatctt attttgatgg ttgccggcat tgcctatgaa
    71701 tatagagttt cagaggatga actcgacaaa gctatgaatg ccatgacgcc atttatcgtg
    71761 caaggagcga ttcaaaatgc cgaagagaca gaccaataat ctcagatgga aagccgaatt
    71821 gctagacatc aaaacaggaa cagacggaaa cgatcgtcca actacaattt acgaatttaa
    71881 gcgtctaata ttctatgaag aactcggtgt gacttctcaa gaaaaatatt tatcacagca
    71941 agccaagaca gacgttgtca gacgaattaa agtcagatgg gataaatcca tcacagagaa
    72001 attaagtgcg ctcaaaattg attctgtaac gtataacatt actcgcattt atacgaatcc
    72061 cgatgcaaga gaaatggagt tgagtttagc ttatgtcgat tagctttgat gaattgaaaa
    72121 cagcgctgaa atcaacaaag ttagcagtgt tcagagacaa agccagatta gggacgatgt
    72181 atccatacat tgtgtactca aatgtgagta acagcaaaaa aatggcatcc ggtaaagtct
    72241 ataaaaaatt accttattac caagtctctt tttttacact tggaacagaa caggatttag
    72301 ttgttattga acaagcgctg caaaatgctg gcattccata ttcagatttt acaggtatac
    72361 aaggtgatga gaacgacgat accgtaacca actattacac atatgtgagg tgtgtggaaa
    72421 atgccaagta ataagaatgg tttttctgaa atatcggatt atttaggaaa cctttcaaaa
    72481 gttgatccga aaaaattatc gttggaatct ttagaagaag cagctaactt ttatctaaag
    72541 cagttgcttc ctaatattcc taagtcgctc ttaaaaaaga aacatatgcg cgatcaaata
    72601 aaagtagtag ttgaaaacga tcaagtgaaa gttcaatttg aagagacggc cttttactgg
    72661 cgctttgccg aaaatggcac aacaaatcaa cgtgcccaac attttgcaag tggtacgtat
    72721 gaacaaaaca aagaaaaaat tgaagaaatt atgactagaa aaatacttga tttatgggaa
    72781 gggtgatttt aattgggaaa acaagatact ttttattttg aaggattgga cgacatttta
    72841 attgcgatga tggcaacgcc agattctgtt ggaactgcac cgacttatag tgaagtttta
    72901 cgattgccaa ttgccacaaa aatcggtgtc aaagggaatg gaacagcatt agaaaaatgg
    72961 gcatccagca aaatgtttcg tcgtgtgtcg cgagaaacaa aacatgaact tgcgttggat
    73021 cacgtgggta ttccgataga agtgatggat gaaatcaaag gattagttgc taaaagcgga
    73081 gtaacgttta gcaaaaatac cgcacgagaa tttccgtact tcgcctttgg atttattgga
    73141 aatattgaaa atggcggtaa aaaagcagtt tggtatccta atacacaact atccaatgtg
    73201 attgacgaag agtatgccac tgcagaggaa gaaacaaaaa ttgacgatgt aactgcaaat
    73261 ctggtttcca tcggactgaa atacaataat gtgatgtatg caagttttga ttcaaataga
    73321 gacggagctt ctctagaatt atttaataaa ttcattgctc aacctgtata cgatgaagaa
    73381 cagtggaaaa cattggctaa agttggaggt gcgggttaat ggctcggtta tctgattatg
    73441 gaattcacgt tgaagactta aaaaattctg ctgttgtaat tattcaaggc gcagaattcc
    73501 ctatttcatt tactatgcaa acgatggaat ttatagcaga tgtgtatggt ggagattatt
    73561 cgcaatttga atctgatatg aacgccatgc tatctaaaaa agaaggacaa atttcttctg
    73621 ctaacttatc gcctagtgat ctaaaaatca tgcgtgcctt gatttatgcc atgctgcgta
    73681 ctggtggttt agaggaagat ccagaaacta ttttcaaatt tttgggaatg agtggagagg
    73741 tgttgtctgc ttatagtacc tgtatggaaa tttttgctag ccagacattt caggtggaag
    73801 acctaaaaaa atccaagaag ccacaagact ttcaaaaagc gcaagcaaaa agaaagaaaa
    73861 acaaaaagaa tcggaagaga taggaactcc ttggagtttt tatatttacg ttgctctcac
    73921 tctattgaat tggagtgaga gtttcttttt aaagtctaca cctaacttgt ggctcaaatc
    73981 ttatttacag tggttacaac aaaacaccga ttttgaacca cctcaatctg taactatgga
    74041 taaatcgcct tggtggtaga aaggagcgct aagataaatg gctggtaaag aatctgatgt
    74101 cgttcttaat tttaaaacga atggcgaagt cagttattcg aaaacaatca aagaaatcaa
    74161 caaagaaatg aacttagccg ctgccgagta caaaaaccaa gtgtctgcga tggacaagga
    74221 tgcaactcaa acagaaaaat tgcgagcggc taaacaaaaa ttagaaaaac aattaggatt
    74281 ggctgaacaa cgatctcaaa tgctgagaga ggaatatgaa aaatctgtca aagaaaccgg
    74341 tgaatattct gctgaatcag aaaaacttta taaacaatta ctcaattctg aaaccggaga
    74401 aaataaactt cgtacagcat tagaacagac gaacgatgca cttaaagaac aaggtgacgt
    74461 ttctgttgat acagcaaaaa aactccagaa aatcgaagaa acaggtgaga aagtaaaagg
    74521 cgttggtgaa aaaatgtctg ttggagtaac cgcgcctatt gtagcggcag gagcagcagg
    74581 acttgcagca tttggtgaag ttgacgaggc acttgatacc atcattacaa aaaccggagc
    74641 aacaggtgat caagctgata gactttcaca gtctttcaaa aacgttggtt caaatactca
    74701 tttaccttta caaacggttg gggaagctat tggtgaggta aatacacaat ttggattcat
    74761 ggataaaaaa ctggaagatt caaccaatta tctcctacag tacgctgaaa tcaatgatac
    74821 agatgtttcg caatcagcaa tatctgctcg acaagctatt gatgcttatg gactagaata
    74881 tgatgatttg aattctgtcc ttgatgtaac aacgaaaaca tcgcagaata ctggtcaatc
    74941 tgtagacgac ttgatgcaaa aagcaattga tggcgcacca caaattaaac aattagggtt
    75001 gagctttggt gaaggggtca ctttacttgg acaatttgag caatctggtg ttgattcaag
    75061 cgcagcttta agtagtttat ctaaagcaac agtggcttat gcgaaagacg gaaaatcttt
    75121 aagtcaagga ctagaagaac tacaagacaa ggtaaaaaat gcaggttctg aaacagaagc
    75181 catcaatgca gcagcagaag tattcgggac taaaggcggt cctagaatgg ccgatgcaat
    75241 tcgtagaggt actttgaacc tggaagattt agcaaaaact gctggagaaa gtgggggagc
    75301 tgtaggagac acattcgatg ctactctcga cccaattgat caagccgatc aagctatgaa
    75361 caatgcaaaa ttagcaatgg ctgacgtagg tgaagcagtc caagtaagcc ttttgccttt
    75421 ttttgaaaaa gcaacttcct tattacagga attctctaaa tggtgggggt ctctagatca
    75481 agatacaaag aattggatca taacaattgc tggtatagcg gcagcagttg gaccagtact
    75541 aatcgttctt ggttcactta tgggatctgt tacaaaaatc gttggggaag ttaaaagttt
    75601 tataggagtt tggcaaggac ttgctggttt atttggaatg tcgggaggct ggtttgcatt
    75661 agcagttata gctattggcg cattagttac tggactaatt tgggcatata ataacgttaa
    75721 atggtttcat gatggagtga attctttctt caaaggtgtt tcagatgtag ctgttgaaat
    75781 atttaatttt ttaagtggtt attttggtgg atttttcgat ggtgttatag caaatttcaa
    75841 taatttttat aatgctggaa aacgaatttt cagtggtttt ctagatttta tcactggagt
    75901 atttacaggg aattggtcaa aagcatggca aggtctagtt gatatttttg gaggtatttt
    75961 cgatggtatt gttgctgtag ggaaagctcc tattaatgcc atgattggat tgatcaatgg
    76021 atttattggt ggattgaata atataaagat accaaaatgg gttcctggtg taggtggaaa
    76081 atcattttct atttcaaaac tgccttattt agcacaaggc ggtcatctaa tcaatggaca
    76141 agcgattgtt ggtgaagctg gacctgagtt actgactgcc aagaatggta aaaccacagt
    76201 tactccatta tcagacgaag aaaaacgcaa agggatcagt ggaagagttt ctggaggtag
    76261 cattgaacag catatacaca ttggcaaagt cgatgcaaac aatccatctg agttagatcg
    76321 tatgaatcgt aaatttgcta aagcaaacaa acaggctatt cgtgatttgg gaggtgttcc
    76381 tatttgagtc gacaatttat gaatccagat gaaccaaatt ttatttggaa aaatcggaat
    76441 gcagtaattg atatgaattg catcattgag gcagagcttc cagatattat gccgaacaag
    76501 cgatacgaaa cttacacgat tcagggccga agcggagaat tgacggagac gtttgatgac
    76561 tatgaacctt ttgatttgga aatagaaggg atcactattc cacattcgaa actgagagaa
    76621 gtcaaacgat ggctcactgg taaaagccaa ttaatcacac ataatgatcc agacaagtat
    76681 ctagaggcta tctgcagcat ggataaagaa gtccctttcg aaaacgagtg gggcttcttt
    76741 tatacattcg atgatacttt tcgttgtcag ccactcaaaa gaaaaatcgg tgaagcacct
    76801 aaaatttttc attctagtgt tatggatatt tttgatcatg gtgacgaaat tgcacatccc
    76861 tatctggaaa tagaatcgaa cggaggagat ataacgatcg ctgtcggtga taaaagccta
    76921 acaatactta atacgttagc tgcaacaatc gtggttgata ctcagcttgg aaaagcaata
    76981 caagaaggtt tgaatttatt tacgcgtggt gattggccag tattgcagcc tgaatggaat
    77041 caggtaaaaa tatccggaaa atttaaagaa gtgcggtttt ggaataggag tgtgtatctg
    77101 tgacgcaaga atttatttat gcttataaaa aaatgccaga tgatttgagc gtgaacggag
    77161 cgtcgttagt tgattgggaa gatttgccag aaatcaatcg tgtgctgaat ggccaatatc
    77221 gtttttatgg taactattca agaagcggac agtatcgctc ttatttaaaa aaaggaaatt
    77281 ttataaaagc gaaggtacca gatggatcat ggcaatattt tgaaatttat aatgtcaaaa
    77341 agaatttgac ctccgtttct gtaacagctc ggcatattgg ttttatggcc aataagaact
    77401 ttattgtcaa gtcgtttacg gataacggca atgggtctca gatcatgacc aatcttaaaa
    77461 acagtttggc atttgatcaa aaatttaact atctttcgaa tgtagggaca acgcaccaat
    77521 ttacagcaag acaagtcgcg ccagttgaag caatcattgg ttcaaataac ggtaatcaaa
    77581 atttgactgg cgtgactagc gcggaacttg atatggataa ctatgatttg aaactggtaa
    77641 aacagattgg atcagataat ggttttcgga ttgattttgg catcaattta gaagcaatcg
    77701 aagaagaaat tgatgaagaa tcaattgtca atagtttgta tttggttggc ggtgttcctg
    77761 ataacgatta tgatgaagac aaagaaccta tcgaatatgg ttatttagaa attgatggag
    77821 taaccaacga gaatcgacgt attgccaaac gtgaaaacgg agattgtaaa acagttgatg
    77881 aattgatcaa atggggcaaa accttatttg acaatgatcg tatccatgag ccaaaagcta
    77941 ctcatacagt cagtatggtg gcgttggaac acacactcga atacggtgac atgtatcaag
    78001 agctagcgtc tttacacttt ggtgatgtcg ctcatgttag ggcgaaagag ctagatatcg
    78061 agataaaaga gcgtatggtc gaatacactt atttcccaac gcttgggaaa tataaggata
    78121 ttgttttagg taatgattta tcactgtaca cttcggcagt aaatactcaa gcacaagaat
    78181 tgaaaaagaa aatcgacaat cgaacagaaa cgttagttca aaatgtgttg aatgcgacgg
    78241 catggatcac tggtaattct ggtgggcatg tcgtttttcg tccagaaaaa gctccatcag
    78301 agattcttat catggatact ccaaatgtgg cgaatgcaaa gcgagtgtgg cgttggaatt
    78361 taaatggctt aggttattca gacaacggag taaatggccc gttcggtatt gctatcacat
    78421 caaaaggaga aattgttgct gacttcatca aagtaggaac aataaatgca gaagtattcg
    78481 aaacttcctt taatgcttat ggtgatgtgt taaaacttgt aaaaggcacg cttcaaattt
    78541 ggaatgaaaa caaaaaaatc atggagctaa ccaaaaaagg tatggaattc tggaatagaa
    78601 aagaatccat tggaacgatc ggaacaacag attcagcagg aaatccattt ccaaatgctg
    78661 taacacctac acctcttgag gaaaattctt tggtaatacg tacaaatggc gatggaaaat
    78721 acattttaat ttctccaact gcagaaaaag gatttgtgtt attaggaaac ggaaaagcat
    78781 attatttcgg tgatttagat attcagggaa aacttactgt tagaggtaaa gaagtgatac
    78841 caggacaaaa tggcggtcca tctggcggag gagaaacacc tggtgggtat cctgatgaat
    78901 taaaaacaga tgcagaaaag agagcttgga gaatatacga tattttgtgt aataacggat
    78961 ttacgaaaca atctgcatgt ggaatattgg ggaacattca acaagaaaca ggaggaactt
    79021 ttgatcctga tactgttcaa ataggtggac cagcatacgg attagttcag tgggatggtt
    79081 cttcatatcc tcttgttggt ccagcaacat gggatggaaa agtttatgtt caaaacttat
    79141 ttaatgctgc aggtattaaa gaaccaataa cgagcttaga tgcacaagtt cgattgctta
    79201 tttggacatt tacaaatgga caatggatgg gcgtagtaca acctacgacg gttgatggat
    79261 ttaaggcctg tactgatcca agacaagcag catatgcttt tgaacgaaac tatgaacgtc
    79321 cggcagcgac acatcctgaa cgtcaagatt atgcagttaa ctggtataac aaatttaaag
    79381 atttaaaacc aggaggagct actggagaag caggactaaa acatttagag tctttgattg
    79441 gacaacgaat tggcaatggt cagtgttatg gcttgtctgc agaatattca ggatatctgg
    79501 gtggttgtgg catgggtgct ggaacaaaat atggtttaac tcatgtgata ggaaatactt
    79561 ctgcagcatc tgatattggt attgcctatg attggtctgc tgttggttgg aaagtgattc
    79621 aaaaccctag atatgatcaa ttagtagttg gtgcaattat taattgggca agaggtggac
    79681 aagtgggttc atggtttgca gacggaactt atggacatac tggcgttatc cgaggcttag
    79741 ctaatggtcg tatgcaaact tatgaacaaa acacagagtt aggtatgatt tgtggaaagt
    79801 tagatcgcca gtattatagt gcaagtgcaa tttcttccat tgtcatacca ccaaaatagg
    79861 gaggtgattt aatggcaaag tggaatgtca tattaagtac aacagaaccc tataattacg
    79921 tggggatgat tcaagttcga caaggcaata aaaacactga agttatggaa gctacaattg
    79981 tcgaaaatgg tcttccatat gatttatcag aatgtaaggt atattttgaa tcagttgttg
    80041 gcggaaaata tccagtccaa ttagaaacaa gaattgtgga tgctaaaaaa gggaaaatca
    80101 aatatatttt tgataaatat tccatgcagt gtttgcatcg acaaacagcc aatttcatta
    80161 tatttaaagg agaagacttg attggaacaa ctcaagactt ctcctatttt gtcatcaatg
    80221 ctgtttcaaa aacagaagga gaaatgggtt cttattggca atcaattgaa gatttaattg
    80281 ctgatatgac agattttatt aatgaaaata aaggcgattt tacggactgg atgaatgaaa
    80341 ggaaagaaga atttgatcgc tggagagaag aacaggagaa tagtttccaa gattggagag
    80401 aaggacaaga atcagattat ttgtcatggt ttgaatcaat caaggatatt ttgaagtcta
    80461 tcgatccagg tggagtaatg ttagc
//
LOCUS       DARPZF010000008        73521 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.008, whole genome shotgun sequence.
ACCESSION   DARPZF010000008 DARPZF010000000
VERSION     DARPZF010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 73521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73521
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.008"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            14..1141
                     /locus_tag="SLE65_000783"
     CDS             14..1141
                     /locus_tag="SLE65_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEI8448097.1"
                     /translation="MAFLFVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVL
                     SDIDETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKL
                     TDLSPALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPK
                     YEARPTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVD
                     FSNGTITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYG
                     KLYIDSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKM
                     KEISERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1361..2503)
                     /locus_tag="SLE65_000784"
     CDS             complement(1361..2503)
                     /locus_tag="SLE65_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEI8448098.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGICLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2508..2693)
                     /locus_tag="SLE65_000785"
     CDS             complement(2508..2693)
                     /locus_tag="SLE65_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEI8448099.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(3047..3292)
                     /locus_tag="SLE65_000786"
     CDS             complement(3047..3292)
                     /locus_tag="SLE65_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8448100.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3286..3687)
                     /locus_tag="SLE65_000787"
     CDS             complement(3286..3687)
                     /locus_tag="SLE65_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEI8448101.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3872..5680)
                     /gene="uidA"
                     /locus_tag="SLE65_000788"
     CDS             complement(3872..5680)
                     /gene="uidA"
                     /locus_tag="SLE65_000788"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEI8448102.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KLITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDICKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWKERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAHYLQKRWSSIPNFSYKK"
     gene            complement(5703..7469)
                     /locus_tag="SLE65_000789"
     CDS             complement(5703..7469)
                     /locus_tag="SLE65_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEI8448103.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IISDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIEPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7482..8276)
                     /locus_tag="SLE65_000790"
     CDS             complement(7482..8276)
                     /locus_tag="SLE65_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEI8448104.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYYQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGEYVDIEQKFIDTFWKNLTNK"
     gene            complement(8286..9662)
                     /locus_tag="SLE65_000791"
     CDS             complement(8286..9662)
                     /locus_tag="SLE65_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8448105.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLIIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQFKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKTSNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANIQTGDVLEKLYNASTLIPSICFFIVGLILFFLYPLSKDKVLENC
                     ELLKQKYK"
     gene            complement(9782..10429)
                     /locus_tag="SLE65_000792"
     CDS             complement(9782..10429)
                     /locus_tag="SLE65_000792"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HEI8448106.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSLENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(10522..11949)
                     /gene="uxaC"
                     /locus_tag="SLE65_000793"
     CDS             complement(10522..11949)
                     /gene="uxaC"
                     /locus_tag="SLE65_000793"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEI8448107.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLGYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQAAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(12023..13102)
                     /gene="uxuA"
                     /locus_tag="SLE65_000794"
     CDS             complement(12023..13102)
                     /gene="uxuA"
                     /locus_tag="SLE65_000794"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEI8448108.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLQTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIRKVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(13105..14736)
                     /locus_tag="SLE65_000795"
     CDS             complement(13105..14736)
                     /locus_tag="SLE65_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HEI8448109.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSNIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            15042..15713
                     /locus_tag="SLE65_000796"
     CDS             15042..15713
                     /locus_tag="SLE65_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8448110.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQHGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKINNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKSI"
     gene            complement(16416..16771)
                     /locus_tag="SLE65_000797"
                     /pseudo
     CDS             complement(16416..16771)
                     /locus_tag="SLE65_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16788..16955)
                     /locus_tag="SLE65_000798"
     CDS             complement(16788..16955)
                     /locus_tag="SLE65_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002404637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448111.1"
                     /translation="MQTLINALQGKNYDYAVKILLDVAKRSLTPAQFAKFNAATIAAG
                     IAINAISCWGK"
     gene            complement(16955..17362)
                     /locus_tag="SLE65_000799"
     CDS             complement(16955..17362)
                     /locus_tag="SLE65_000799"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448112.1"
                     /translation="MSRFFKFFSLLGVMLIGLSTLVGAGTSVYAAEKVNEVPDIETQR
                     QQAVESLKFYLEEAGYVDTETHQYIVTDLEAIQKKAELDGSEGIAGKFILENFVQPTG
                     KRQKRDLQKYAACVVMNSLPFGVLFGIYLIVKI"
     gene            complement(17863..18057)
                     /locus_tag="SLE65_000800"
     CDS             complement(17863..18057)
                     /locus_tag="SLE65_000800"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448113.1"
                     /translation="MKDQKTNNKTGERSACSWAFTGAGLLHSGIYTAAALGLSLTGVG
                     AAVIPFAVGTAYGIAGAAIC"
     gene            complement(18071..18409)
                     /locus_tag="SLE65_000801"
     CDS             complement(18071..18409)
                     /locus_tag="SLE65_000801"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448114.1"
                     /translation="MKRIVKIFGILGVFLIGLSTFVSAGISVDASETNNFLVKQQETE
                     INIIQNNLATHKDSKGNRLVYIIDESDLKSSLDRINSEITVSEIQQYLNEFNRSIQKK
                     WPWMANRSAS"
     gene            complement(18453..18785)
                     /locus_tag="SLE65_000802"
     CDS             complement(18453..18785)
                     /locus_tag="SLE65_000802"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448115.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRKEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLVWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(18799..19056)
                     /locus_tag="SLE65_000803"
     CDS             complement(18799..19056)
                     /locus_tag="SLE65_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448116.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KVYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(19251..19787)
                     /locus_tag="SLE65_000804"
     CDS             complement(19251..19787)
                     /locus_tag="SLE65_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448117.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLTTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDYMT
                     DRCIKDNSIDVDPHVQMKTTGKLHQVTQDIENPDQYLLFGEETTNEVTQFVLLQLKVD
                     QEAQKIDAIKIYYVRSVY"
     gene            complement(19808..20899)
                     /locus_tag="SLE65_000805"
     CDS             complement(19808..20899)
                     /locus_tag="SLE65_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEI8448118.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEDGGEATGLAVAFNWE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESTYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKDCYDYYGFLVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYQGAMSIIKSYNLTEYDTFAIKHWNSLPTKK
                     SSLVAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YDWTAYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSDGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(20907..23117)
                     /locus_tag="SLE65_000806"
     CDS             complement(20907..23117)
                     /locus_tag="SLE65_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448119.1"
                     /translation="MAYIKRKEKKWCVWLFLTVGFGLFFVGGLVYAVEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYLLLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPAFDYMIMNTLKSFLSLMFQKSFYSVIILVAFLIY
                     NIVDDLILMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGGQVINPFELGGRSNQDLPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQSSKQQGNNQRKPLLNKGIAFVGQSIPLPAGKVPVPQLTAAGSLS
                     QQIHQVKNQAKNGSYPAMQQLLNQYSVPKSSVATLSGNRSVQRQIQRSSESKPSISVP
                     KSLQPAFSSFNNPVEQSKKIEKKNETLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(23133..25661)
                     /locus_tag="SLE65_000807"
     CDS             complement(23133..25661)
                     /locus_tag="SLE65_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEI8448120.1"
                     /translation="MVLVKEPVKALKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFYDVLNLIWLDVAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRMPKEHKGLLQLEDELGTSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEYKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATIIQQLHTTIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAIGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVEYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILTHLRLEVNEANLSEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQIEEQDTLIMQ"
     gene            complement(25715..26125)
                     /locus_tag="SLE65_000808"
     CDS             complement(25715..26125)
                     /locus_tag="SLE65_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448121.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFFIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYVV
                     RMMNGDCVYYNWDKVSNNALEELLFANKYVYLED"
     gene            complement(26138..26356)
                     /locus_tag="SLE65_000809"
     CDS             complement(26138..26356)
                     /locus_tag="SLE65_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448122.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(26353..27345)
                     /locus_tag="SLE65_000810"
     CDS             complement(26353..27345)
                     /locus_tag="SLE65_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEI8448123.1"
                     /translation="MKKRQLRRKEKVYTEKVPNQRKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSQSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQEILKKEFYAQNFIQEPGSVSGIRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMDPENKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKTFIVKATVVFRDGDTSLLQKEQMTLVITKKTNQYYVEKLTHNWLDRKGDERK"
     gene            complement(27424..28335)
                     /locus_tag="SLE65_000811"
     CDS             complement(27424..28335)
                     /locus_tag="SLE65_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEI8448124.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLSDVETELNGGTTEKPAEPEHLQPEKPEKEPVAPEPEIPESTLPTDPIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSETNTDSSSTEQPTMSFTSEEPKEEPKQPAEKSEAIPK
                     ENKPIVPAKEVTVSVTPNGEITTNNSQGMSVPIVTSNVEELTHIPTPTTPLKAEGGQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEVKTADGKTKVLPKTGEEIHVVLS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(28354..28698)
                     /locus_tag="SLE65_000812"
     CDS             complement(28354..28698)
                     /locus_tag="SLE65_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448125.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLGPRTERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(28718..29275)
                     /locus_tag="SLE65_000813"
     CDS             complement(28718..29275)
                     /locus_tag="SLE65_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448126.1"
                     /translation="MSLEFLGEPIEKEEFVSHYMDLFIRVIKKLCTIDEFYPREQDYL
                     AAERIKISLLWEKFTDENNRPPDYRYLSDCLTNNVLSKEYLFHKREKNQMSAEHFCDC
                     YIALLRSQQLLTVERYGAEFGYVMQAERHRATRCYEKEDQVIDGYEELCIRNNRYLQQ
                     RLYEKLMMDFSDLYRGYECSVIQER"
     gene            complement(29355..29855)
                     /locus_tag="SLE65_000814"
     CDS             complement(29355..29855)
                     /locus_tag="SLE65_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448127.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPKEYPIEKRELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPINFLKKC
                     HLRILP"
     gene            complement(29856..30401)
                     /locus_tag="SLE65_000815"
     CDS             complement(29856..30401)
                     /locus_tag="SLE65_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448128.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGTLKFIRFYRFSLPVPAILAVK
                     KGCDKMKIYENCVAALSNEKPLVEEISLATVTWEMNRQPTEEQTYLSLEEIELELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(30398..31654)
                     /locus_tag="SLE65_000816"
     CDS             complement(30398..31654)
                     /locus_tag="SLE65_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEI8448129.1"
                     /translation="MTPIELRNYRKKLSAIHASGGGKKLLSQKRFAQLLGCSVDYIKK
                     MEQGKKKIPEDFEKRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKIVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKQTVTQNVLVQFSGQGCREYEEVMREQRTD
                     WRTWLYSIWKNQGKLEAGYKRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKKFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISEIEAL
                     TKYGIYNRYELRLANEKATQAVEAFILDHSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDERWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIENAELNDEQQSYLEWMGTSGGKIA"
     gene            complement(32017..32331)
                     /locus_tag="SLE65_000817"
     CDS             complement(32017..32331)
                     /locus_tag="SLE65_000817"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448130.1"
                     /translation="MGEVLYRVSSAAGEISPDFAVRRLYEWINKVEYYTKGSYVFRRI
                     ERETLFVTRNQIVLTKEDILRFRQVYRLCKEKNIQLRLAILQCFAPEQYKELQEKEDS
                     LV"
     gene            complement(32458..33651)
                     /locus_tag="SLE65_000818"
                     /pseudo
     CDS             complement(32458..33651)
                     /locus_tag="SLE65_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
     gene            complement(33841..34197)
                     /locus_tag="SLE65_000819"
     CDS             complement(33841..34197)
                     /locus_tag="SLE65_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448131.1"
                     /translation="MNLDKTNQTLREIMVCCQNIQQLIEYFGDNPTIFIQTNEYICAV
                     IGQCMFLRDLVRFSLPYQWKQDHQEVVWIRVVRICNMCAHPYKNRLNLFRLWFFIKCD
                     IPVLVAFCQKFLAQEK"
     gene            complement(34263..34715)
                     /locus_tag="SLE65_000820"
     CDS             complement(34263..34715)
                     /locus_tag="SLE65_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448132.1"
                     /translation="MGLKFPNNYDITEALDETCIGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNSNPKQSQEKGLDQKQPSADSKEKEKK"
     gene            complement(34717..35082)
                     /locus_tag="SLE65_000821"
     CDS             complement(34717..35082)
                     /locus_tag="SLE65_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448133.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIEEVL"
     gene            complement(35099..35293)
                     /locus_tag="SLE65_000822"
     CDS             complement(35099..35293)
                     /locus_tag="SLE65_000822"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448134.1"
                     /translation="MEKKNINICFLSGKECTYEECTDISVHERDGMLIVDMSPSDEPF
                     VVKHYFPLCNIESFRIDCEF"
     gene            complement(35310..35555)
                     /locus_tag="SLE65_000823"
     CDS             complement(35310..35555)
                     /locus_tag="SLE65_000823"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448135.1"
                     /translation="MEEIFFCMMVEFLFVSIGFLIMGEAIMIYLFPFDSKDECIFSSI
                     IIFFILACVWILAREIYHQFVLEDGKGIITWFLQKRK"
     gene            complement(36271..40566)
                     /locus_tag="SLE65_000824"
     CDS             complement(36271..40566)
                     /locus_tag="SLE65_000824"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HEI8448136.1"
                     /translation="MYAKTKMNWLKALALVALSQFCFLVGTAQAHAEETTATQPTVEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPVT
                     SQPVEETASITTPASETSTPEGEKAAEATPSVKPESSEKQAEEKQRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKLNKESTASIEDQKKKEQDIPKTGTPTLLVTVP
                     TNRSVRVRRATNTAVLGGRKIDWGENIGVTSSPNNPNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALENYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLLNNFDVRATFHNQTHTIKIGETLKVKSGNDFLQRV
                     KGIQKPKGINVSIHGNEAWITVTKEAPEKAKIHFNQIEVLGTPLAYRRPGAQTIGILN
                     PFEPGDSVVNLTILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KNMNGKVQAEIKDLDPGKYVLKEIKAPKGYALSDETIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKIANKDLVDSTNPDNKPKLAGIEISLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKERYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVT
                     FTLYNGKGQAIGKYTTDQNGEILVKGLVANNYYFTENVPLESFQPNTGKQAFTITFRQ
                     NAPDDGETLLVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQEGKEITSILTFIADKANGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAVHVDINDDNQSVRVNNPTVHTTAVFEDGLTIADPTGLFTLNDTVEINE
                     ILPGKAYLVKGILMDKATGEALLVHGQPVESAVGFIAKAENETVIVPFTFDLTGLNGR
                     EMVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLIVGKTYTVNGVLMDKVTEKPVLVDGKEVSSTLTFVAETTDGTVNLDFILD
                     AHALRSKEVVVFEDLFREGVLLASHADITDKDQTIKIVSPTITTKATNANGGKEILAL
                     PNQKVVEWVQVNGLAIGQIYKLIVQGYLTPDGTPFEGTHAEKVFMADKEMMEFLFEFI
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQFVEAPKPPQPVK
                     PNEPQPVKEVKQAAMVPMLPKTGSEDNVLWIMIGMIFVLAAGLIGYDLYKVRD"
     gene            complement(40713..40952)
                     /locus_tag="SLE65_000825"
     CDS             complement(40713..40952)
                     /locus_tag="SLE65_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448137.1"
                     /translation="MIDISIPEDLKPDPATIGNSGMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMIFGDGEVANKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(41042..41314)
                     /locus_tag="SLE65_000826"
     CDS             complement(41042..41314)
                     /locus_tag="SLE65_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448138.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            complement(41397..41648)
                     /locus_tag="SLE65_000827"
     CDS             complement(41397..41648)
                     /locus_tag="SLE65_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448139.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFVESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            complement(42646..43557)
                     /locus_tag="SLE65_000828"
     CDS             complement(42646..43557)
                     /locus_tag="SLE65_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8448140.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGQLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEISKESNRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFNKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            complement(43754..45589)
                     /gene="lepA"
                     /locus_tag="SLE65_000829"
     CDS             complement(43754..45589)
                     /gene="lepA"
                     /locus_tag="SLE65_000829"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEI8448141.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            45736..46956
                     /locus_tag="SLE65_000830"
     CDS             45736..46956
                     /locus_tag="SLE65_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8448142.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            46976..47470
                     /locus_tag="SLE65_000831"
     CDS             46976..47470
                     /locus_tag="SLE65_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HEI8448143.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            47448..48134
                     /locus_tag="SLE65_000832"
     CDS             47448..48134
                     /locus_tag="SLE65_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448144.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(48285..50894)
                     /gene="clpB"
                     /locus_tag="SLE65_000833"
     CDS             complement(48285..50894)
                     /gene="clpB"
                     /locus_tag="SLE65_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HEI8448145.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQPNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(51145..52191)
                     /locus_tag="SLE65_000834"
     CDS             complement(51145..52191)
                     /locus_tag="SLE65_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HEI8448146.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            complement(52202..52474)
                     /locus_tag="SLE65_000835"
     CDS             complement(52202..52474)
                     /locus_tag="SLE65_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEI8448147.1"
                     /translation="MDVLLHNLLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            complement(52509..53417)
                     /locus_tag="SLE65_000836"
     CDS             complement(52509..53417)
                     /locus_tag="SLE65_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HEI8448148.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            complement(53549..54781)
                     /gene="pepT"
                     /locus_tag="SLE65_000837"
     CDS             complement(53549..54781)
                     /gene="pepT"
                     /locus_tag="SLE65_000837"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEI8448149.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            complement(54796..55917)
                     /locus_tag="SLE65_000838"
     CDS             complement(54796..55917)
                     /locus_tag="SLE65_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEI8448150.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            complement(55914..56615)
                     /locus_tag="SLE65_000839"
     CDS             complement(55914..56615)
                     /locus_tag="SLE65_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEI8448151.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            complement(56759..57199)
                     /locus_tag="SLE65_000840"
     CDS             complement(56759..57199)
                     /locus_tag="SLE65_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448152.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNAIAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            complement(57328..58254)
                     /gene="dnaI"
                     /locus_tag="SLE65_000841"
     CDS             complement(57328..58254)
                     /gene="dnaI"
                     /locus_tag="SLE65_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEI8448153.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            complement(58254..59627)
                     /locus_tag="SLE65_000842"
     CDS             complement(58254..59627)
                     /locus_tag="SLE65_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEI8448154.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            complement(59650..60141)
                     /gene="nrdR"
                     /locus_tag="SLE65_000843"
     CDS             complement(59650..60141)
                     /gene="nrdR"
                     /locus_tag="SLE65_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEI8448155.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            complement(60453..60785)
                     /locus_tag="SLE65_000844"
     CDS             complement(60453..60785)
                     /locus_tag="SLE65_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEI8448156.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHISDEQKIEEQRMKH
                     YTGIEEKL"
     gene            complement(60837..61466)
                     /locus_tag="SLE65_000845"
     CDS             complement(60837..61466)
                     /locus_tag="SLE65_000845"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEI8448157.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            complement(61430..62266)
                     /gene="mutM"
                     /locus_tag="SLE65_000846"
     CDS             complement(61430..62266)
                     /gene="mutM"
                     /locus_tag="SLE65_000846"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEI8448158.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            complement(62311..64956)
                     /gene="polA"
                     /locus_tag="SLE65_000847"
     CDS             complement(62311..64956)
                     /gene="polA"
                     /locus_tag="SLE65_000847"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEI8448159.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELADKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            complement(65082..65765)
                     /locus_tag="SLE65_000848"
     CDS             complement(65082..65765)
                     /locus_tag="SLE65_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEI8448160.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            complement(65758..66243)
                     /locus_tag="SLE65_000849"
     CDS             complement(65758..66243)
                     /locus_tag="SLE65_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HEI8448161.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            complement(66550..67884)
                     /locus_tag="SLE65_000850"
     CDS             complement(66550..67884)
                     /locus_tag="SLE65_000850"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEI8448162.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            complement(68015..68776)
                     /locus_tag="SLE65_000851"
     CDS             complement(68015..68776)
                     /locus_tag="SLE65_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEI8448163.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            complement(68792..69274)
                     /locus_tag="SLE65_000852"
     CDS             complement(68792..69274)
                     /locus_tag="SLE65_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEI8448164.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            complement(69294..71474)
                     /locus_tag="SLE65_000853"
     CDS             complement(69294..71474)
                     /locus_tag="SLE65_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEI8448165.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            complement(71618..72349)
                     /locus_tag="SLE65_000854"
     CDS             complement(71618..72349)
                     /locus_tag="SLE65_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEI8448166.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            complement(72418..73359)
                     /locus_tag="SLE65_000855"
     CDS             complement(72418..73359)
                     /locus_tag="SLE65_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEI8448167.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
BASE COUNT        21587 a        15406 c        11408 g        25120 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgaagatat
       61 caatgatgat ggctcaagaa aaaaagtgga gaaagttggc ggagacaccc gaccagaggc
      121 cgaagctgct ttacgaaaag ttttatcaga tattgacgaa acaggacaat actttttagg
      181 tacggatact cgagtaaaac aataccttga tttttggatg gaggaatacg ttaaactaaa
      241 tctaaaatac aatacctatg aaaactaccg atttaccatc aaaaatcata taaacggtta
      301 tttaggaaag aaaaaactta cggatctctc ccctgctctt ttacaaaatt tcatcaatgc
      361 tgaatttaaa aagggttact cgaagaaaac aatgactatt actcactctg tccttaagaa
      421 tgcgctgaat atggcggttt atccttgggg attaatcaag caaaatccta tgctgtatgt
      481 aaaaatacca aaatatgaag cacgaccaac gactaaaaaa gatctaaaaa tcatttctct
      541 tgaggacttt gatcatatgc tagaaattac tcctgaagga catcctttct atattccttt
      601 gaatattgga ttttatacgg gaatgcgcgt tggcgaagtt tgtggtctga cgtgggatga
      661 tgtcgatttt tcaaatggaa caattactgt agagaaacaa atggtaaaga atgacggcgc
      721 atgggtatat ggtacgccaa agacaagcag ttccaatcga acgattttta ttggacaaac
      781 cttgctagca attctgaaaa aacataagaa acaacaatta gaaaatcgaa tgaagtatgg
      841 aaagctctac attgattcaa atgcagtatg tacgaaggaa gacggtgagc tagttacgcc
      901 aagtgtagtg aaatggaata ctaggaggat atcgaatgca ctctccctct cttttaactt
      961 ccattctctc agacatactc atgctacact tcttctcgaa aatggcgcaa aaatgaaaga
     1021 aatctctgaa cgattgggcc acagcagaat ttcaattacg atggatactt actcgcatgt
     1081 aacagataag atgagaaatg aaacggtcga tatcatggaa aatcttagaa agaattcttg
     1141 atttttgcca ccgaaaaaaa ccaccggtgg caaaccggtg gcaaatccat gtaaacatgg
     1201 tttatttttt acactgtttt caaacaaacc cttgctattt cttcggttcg tcctcgtcca
     1261 ttttcgatac cgacagctag cttataaccc aaggtatatc aacataaaaa aaaaaaaaaa
     1321 taggctgtga cagcagcgtg acagcaaaaa agatggaaag ttaaatatca aacctcgtaa
     1381 tttcatttgc gagtgcttga tttgtttctg gatataagtg tccatatttg tccaaagtag
     1441 ttttaataga ggcatgacct agacgcttag atattgcata gatattttta ttatgttcaa
     1501 ttaaaaaggc aacatgcgag tgtcttaatc catgcatatg aattggtttt actcctgcaa
     1561 tttcagctaa tttttttatt ctgcttaaaa tagttcttgg agatggcggt aatccatcaa
     1621 aagaaaaaac caattctata tttttcccaa ttgattgttg agtttttttc catgttttta
     1681 aatcttcaac ggtttgtctg tctaacgaaa ttatccgaat acttgatgta ttttttgttt
     1741 cagcaaattc ataatcttgt cttgtacgga tgtaaattga cttatttacg ctacatctgc
     1801 catttattaa gtcaaagtct ttccattgta acgctaagag ctcctcactc cttacacctg
     1861 taacaaaaat aaaacgcatc aaacgtttat aaaattcttc ataaaaatcc ccgtgataaa
     1921 cactattata tactttctta aattcatcaa ctgtccaaaa ttctacttga ggacgctgag
     1981 tttttatttt acctatagta tctacaggat tttcttcaat aatttcaagt acaattgccc
     2041 ttttaaaaac tactctcaac ttattgaata tctgtttaat ataatttggt gataatggtt
     2101 gctcaatgcc cttttttaca acatggattt tcgataaaaa ctgttgaaat tcctgtatat
     2161 gaattggtcg aatctttaca acctgcattt ctccaaaaaa atccaatgca cgttgtaaaa
     2221 tatgatctgt tttcatatat gttttttcta cagttcccaa cttataccaa ggaaaaaaat
     2281 actctcgata aaaatcatga aacgttattc cttgcagaca aattccttgt gaatcagaaa
     2341 aactttgttt taactcttcg agtccccttc tagcttctcc ttgagttttg aagcctcttc
     2401 tggtcacttg aattcttttt ccaaagcgat cttgtcctaa agttgcagaa aaaaaccaag
     2461 tgcctctttt tctgtcttta taaacattcg caattttcct cattttacta ttcctcccaa
     2521 gaaatatgga gaacttcttc taaaattgaa ataggaattc tttttatttt tgaattacga
     2581 taaaaaaagt atcctttctc aactaaaagt tctttacatt ccttgaagat tttattagca
     2641 tagtactgag aaaaacctag attaatcaaa tcttttcgag tagctgtttt cattatagca
     2701 ccttccttac tttttttcat ttatttctat cagctgcttt tgtcaaaagc acataggaat
     2761 ttcacctctc cccaagttta cggcgagcct tacggaagta tcattatccc aactttaaat
     2821 catcgctttt tattgactat aaaaattatt ttagaatatt tatcgctcct tctttacagc
     2881 aagaaatcat ggcgcaacta aaatatgctc cttaaagtgt taacgtactg atagaatcta
     2941 tttaattttc aatgaacaat aggttttcta cctaaaagaa tctactaatt ccttaactat
     3001 tagaagattc ttttaaacag aaaaagtgga aaggagattt ttttaattag ttaattttaa
     3061 attttaagat cgcttctatt aatttaattt ctagctgact tatcatatat tcatctacat
     3121 aggtaacgaa ttgacctacc tcgttaaatc catttgtcaa acataactta gccatataac
     3181 tatgataatg tttgagtatc atcttgatcg aaattggatc tccttctaga gcagataaga
     3241 taatggatag tggaactaat aggtactgcc gctttttgga tttatctacc ataggtcata
     3301 ccccattttc aattgttcaa ctgccttctt tcgttgatac cagataccac ttgtgctcat
     3361 attgagaatt ttaccgattt cagcatcatt aaaacctgca aaataataaa gtaggataat
     3421 ctttcttctt atctccgata actgatcaat tgctgctgat aacttttgat ctgaaattaa
     3481 tatttccatt ccaaataaga aatagacatc ttgttcatca aaatgagttt gggaatacct
     3541 gccttcattt gaatctgcca atggttcctc attatccttt atgttagcat ttcgttttcg
     3601 aatagactta gcttcgtttc gtaatacttt tttacagtag gcatcaaatt ggtgttgtat
     3661 agatatgtca ttgtaatgtt gttgcatgat aatatgctcc tttttccccc tttccactaa
     3721 tacaacaatc agagagcccc tttttttcga aaaaactaga aaaaaacata aaaatattta
     3781 tcattcttta aacagaaaat ctttctataa aaaacaaaaa aacgattagg ctaggctaat
     3841 cgttttttga acattcttaa aaaaatccaa attatttttt ataactgaaa ttgggtattg
     3901 atgaccatcg tttctgtaga tagtgagcaa tcattttagg ttttctatct ctagtaaaga
     3961 ttcctttctt atttccttgc actcttaaaa tcccttgact cgttgcaaaa tctgcaaaat
     4021 tccacacttg ttcaccaaca aaattttcac atgtatctat tacttcgtga tttgcttcgt
     4081 aataagccac ttgatactct tctgtaaaca ttgttggtac tgtatcatga aatccagcta
     4141 ctgtatctgc tccatattct gtaaacatta ttggcgtatc aggacatctt tctttccatc
     4201 catctagctc ttttttcaac agatattttg catgtgccag atcccctccc gaaacatacc
     4261 aaccataata acgatttaaa cataaaacat cgacaatatc tcctacctta caaatatctg
     4321 gcgttgattt tagataagta actattgtta caggtctttt ctgcggatca agttctttag
     4381 ttaattcaac taaaggttca aaatattctt tagcaccttc ggaatccgaa tctggttcat
     4441 ttgcaataga ccacattaca acacttgggt ggttcttgtc gcgttctatc aattccttga
     4501 tcaccgtttt atgagaattt tctgttcgta tctctttcca cgtattatgt ttttccacat
     4561 tatcatctaa taaagtggcc atgaaattta aatgtaaccc tactgcaggt acttcatcaa
     4621 taactacaat accttctcga tctgctaatc gcataatttc ttctgagtaa ggataatgtg
     4681 atgttctaaa agaattagca cctatccatt tcattaaatt aaaatcttta atatttacag
     4741 cctcattcaa accacgtcca ttaacatacg aatcctcatg cttaccaaat cctttaaaat
     4801 aaaaaggttt attattaatc aaaaatttgc cattggtaac ctgaacactg cgaataccaa
     4861 attcttctgt ataggtatcg atcactttat tatcatcaat taaactaatt ttcatactat
     4921 ataaataagc atctagaggt tcccaaaaaa ttggattctt aagctgaatc attcctttct
     4981 ttccttcagc ttcagctaca agttgagcct cttcgtcata tatcgctatt aagatttttc
     5041 cggtccattc tgtatcgata ttgaattcta cacttgcatc caaatcagtt attcttgtat
     5101 taatagtaat atcacttata tagtctttcg gagttgtata taacttaaca ggtctatgaa
     5161 tacctgcata attgaagaaa tcaaaattaa ctaagttttc cttttttata tccccatttt
     5221 cctgtactgt ttccttcata atccccacag gtaaagtact atcgtcaata atattgttta
     5281 cagcaactgt aattcgatta ttcccgtctt ttacaaaccg attaatttca gactcaaatg
     5341 gtgtaaaccc acctttgtgt tgagtaatca actttccatt caaaaaaact tttgcttcat
     5401 gtgttgcaga tccaaaacga agaactaatc tttcttctaa taatctttta ggaagagtca
     5461 cttctttttc ataccacacc catccaacat gatttctaat gttctctgtt tcaaataaat
     5521 cattataaga agagggaact gaaatcggat aactctcttt ttcatttatt ggttctaaag
     5581 caagttcttc ctgtaagtca tcatttgtat ctaatttaaa tctccagaga ccgcttaagt
     5641 caattacttg cctcgtctct gtcataatgg gatacaacat ataaaccact cctatctaaa
     5701 tattaaataa atgtatcctt taaaccacaa taagcatcta ttggacttac tcccttaaat
     5761 tcagaaagac ccattagttt gtccaccaat atttctaaag tttcttgttt tccatcataa
     5821 gtattaatat aagtctttac ttgaggtaca tcagccaaat gaaacggaca ctgtacagat
     5881 acaaaaattg ttggaatttc atgaatgtaa aacggtatat ccggagttcc tttacttgct
     5941 ggccagacaa ttcgttgaac tgtgcctgga ttaacattag ctatattaat gatcaagtca
     6001 tattttttag ttaaattttt aattggtctc ttagcagcat atattccagc tatattttta
     6061 attttttctt cttgcgataa tcctttcaac tcttcttcag gtgaaatgta tttttcaact
     6121 tcaaatcctt ttgctgacaa aatctgtttc aataaatcaa tggcttgagg tctatttcca
     6181 gcaactactt caccaaaccc accttttacc ccatgtacat ctactagtaa aatcctttta
     6241 tatttttctg gttcaatagg ccaaatatct tgtttatctt taactaatgt aattgcttgg
     6301 tcagccacct ctttaaaaat tgatttattt tcaattaaac caattttttc cagagcttct
     6361 tgcttaggta ataaaatttg ttcttttgct tttttgtgta atcccaattt agcttttaac
     6421 cctaaaattc tttttaaggc atctaataac cgatcatcag agataattcc tttacgataa
     6481 ccttccatca tataattaaa gtcttcatct ggatcattaa aaaatagaaa tagatcacat
     6541 ccagctgcaa tagaagtggg caataattct gatcgtttca ttgccccagt cattcctaac
     6601 atatgactag catcagtaac tactaatcca ttaaatccga gttttcctct aagtaagtca
     6661 gtgattaatt cttttgataa agttgcagga agtaaatctt catctttcag atcaggatta
     6721 aaatgttttg aataagctgg catatggata tgacctgcca taatcgaagg taatccagct
     6781 tctattaaac ctgagtatac ttttccaaaa gaattatccc attcttccgt acctaaacta
     6841 ttaatactaa aagatagatg ctgatctcgt tcgtcaatac cgtcaccagg gaaatgttta
     6901 gctgcaggca aaattccact ctcctgaata cctttcatat aagctaaact aagttctaaa
     6961 actttatcag ggttttgtcc aaaagatcga ctagaaatga taggatttct ccaatttcta
     7021 ttaatatcta caataggagc aaaactccag ttacatccaa tagccgatgc ttcaatccca
     7081 gaaactctcc ctaattcata agcatatttc gcatcatttg ttgcaccaat ttttacttct
     7141 acaccaactt cagtaccatc tgtacaagct ccgttaccac ctgcttccgt attagcagca
     7201 attaataaag gaattttgct ttctgtttgt aggatatagt tttgatcata tacctcatca
     7261 gcagttcctg ggttatatcg tacagctcca atatggtact gattgaccat attactcaag
     7321 taatttttat cacgactaga tcccatatta acaaacaatt gacctatttt ttcttccaaa
     7381 gtcatagaat caatcgtctc ttcaatccaa gaaatagcat cttcatctaa attatatggt
     7441 ttttttcgta agtctacttt tatagtcatt ttctttctcc tctacttatt agtaagattt
     7501 ttccaaaaag tatctataaa tttttgttca atatctacat actctcccga taaacattta
     7561 aataaaacat cagttcttaa gttttcccat gattcttttt ctttattaac caaaatagga
     7621 taaaagaaaa ctttattttt atttgcagct tctagatcac caggagaatc accaatcatt
     7681 aatatcttat ccaaatcaca accattttca attacacttc gaataatgtc ttcttttttt
     7741 cctttatctt gacaacacag ttcatcaact aatgataata attcatgtct ttcccattct
     7801 tcttgaacag cttccttatt agctgagctt acaataatta tcttcccata ttttttcaga
     7861 gcttttatag tatctctagc acttaaaaag ggtttatcta atcctttagc ttgactaatc
     7921 tgttgattga cttcttccga ccattttaaa gcttttaata aatcctctga ctgataatat
     7981 tctatttccc tcttcaaaga tggattagac aattcttttg ttagagatac ccagtgcttt
     8041 aatcgattaa tggatgttac atcatttttt tctaatgttt taactaaacc taaaaatctg
     8101 tttattccac gagtctctga atataaatta atattattcc aatcctgtag gaatttttct
     8161 ctatgatgaa catcaaaaat ctctgcagca attggtccga aaaagagatt gtgtttataa
     8221 gtcatcgtat ccataacaca gccatctgaa tcaatacaaa atatccaatt attcatattt
     8281 ctctcctatt tatatttttg ttttaaaagc tcgcaatttt ctaagacttt atctttagat
     8341 aatggataaa ggaaaaataa aattaatcct acaataaaaa aacaaattga tggaattaat
     8401 gttgaagcgt tatataactt ttctaaaaca tctcccgttt gtatatttgc taaagagtca
     8461 tagcctataa tagaaagagt ccaacctccg acgcctccag ctagagcttg acctattttt
     8521 ctagcaaaag aatataccgc atatacggtc ccatcttctc tttgatcaga ctttacttct
     8581 tgatcatcaa taacatcagt aatatttgcc caaataacag tattaaacac acccaaaccc
     8641 atatagccaa ccgaactaag aattaagaat acatacatat tactagtttt tatcaaaaat
     8701 aagatcaaat atactattgc tgaaaagaac attcctactg atgccagttc tttttttcca
     8761 tattttttac ttaaaaacaa agttaaaggt gaaacaacta ttaaaaccaa aataggattg
     8821 ataaaattca ttaaaactat tccctgtgca tcattatagt aatcaggaaa tacataatta
     8881 ttcatactca taattaataa ttgagcaagg agtaagaaaa tagccgcacc aattatagaa
     8941 agtaatgccc tatttttaac taaccctttt aaagatttta acaatgaaac tttgaattga
     9001 gattggtcaa ttcttactcg ttcagtagtt agtttataac atattaaata acaaataagt
     9061 gcacatatcg aaaatattcc cgcaacaatt gtaaaagttg atccaccacg aactatttga
     9121 gcgcctgaat catctcttgt ataaataaat aatggtgtta atacaccaat gatcaaactt
     9181 gctaaagtag ctccaacatt tcggaatgtc gatagcattg ttctttcttc tgtaatagaa
     9241 gtaatagctg atgccattga tccataagga atatttatag atgtgtaaaa aatactcccc
     9301 cataatatat acgtaacata catgtatact accttaacgc tcatagaagc tgaaatcata
     9361 gaagtttgat acattaaaaa acttgctaaa gcgactggac cactcattct taaaatccac
     9421 ggtttaaact taccctgctt agttgctttc gatctatcaa caatacgccc catagttaca
     9481 tcagtaactg catcgataaa tcttgctact aaaaataatg ttccaacggc agctccgctt
     9541 atccccaata cttttgtata aaagatcatt aaaaaagaac tagcaaaaat gaaagtaaaa
     9601 tcgtttccaa aatctccaaa catatatcct attttgtctc ttataccaaa ttttctttcc
     9661 atacaattct ctcccttctt ttgttaagcg ttttcattct tatgaaagta cgtactatac
     9721 tctgaagcgt aaagagtcag tatttatttt ttacatttca gagtattatt tgttttttct
     9781 cctaataatt ctttatctca taaaacttat ctatatattt actagctact cgacttactt
     9841 cttcaaaatc acctttttca acagaagcca ataaattccc acctacacca actgcaacaa
     9901 ctcctacttc aaaccaatct tctaagttct ctagacttac tccgccagta ggcattatat
     9961 ttacgtgtgg taatggagct tgataggctt ttacaatgga tggaccaaaa gcagaacctg
    10021 ggaatagttt aatgatatct acgccagcag taagtgcctc ctttatctca gtaattgtca
    10081 tacaacctgg taaataagga atttgatata aattacaaat ctcagctgtt tgtcgatcaa
    10141 aagatggact aacgatatat tctgccccag ccataattgc gatacgagca gtaaacgcat
    10201 ctaaaaccgt accggctccg attattacat ctttttgatc agcatatttt ttagcaattt
    10261 ctttgattat ttcttcagca ttaggaactg taaaagttag ttcaatccct ttaattccac
    10321 ccgcaataat tgaatttatt gctttaatgg cctcatcctt atttttccca cgtacaaccg
    10381 caatcactcc agccgcttct aacttactta aaatttctac ttttttcata tctatctcct
    10441 ctatctcctt cttttatgga tacatacttt gtctagctgt actaacttaa aaagaataaa
    10501 tttaagcttt tatttcaagt attattttct acttccgatt tcaaaaaaat taaaataatt
    10561 atacgcatta cgataacaaa tattctccac tatctgacta agatacattt catcatctgg
    10621 aattcggcct gctttaaccc actcgcttag taattgacat aatactcgac gaaaatactc
    10681 atggcgagga tagcttagaa aacttcgaga atcagtcaac atacctgtaa aattcgacaa
    10741 caaactttgt tgcgccatcg tagtcaactg ttgacgcatt ccttcagctg tatcattgaa
    10801 ccaccaagca catcccaatt ggattttttg aatcataccc ccttggaagc tttgcattgc
    10861 tgttgctagt ggaagccaat cagttggatt taatgaatat aaaattgttt ttggtaagca
    10921 cccactcttt tcagcggtat cgaacaatgc tacaacattt tgtgtcaaac tagcttgatc
    10981 ccccatcgaa tcaccaccga catctactcc aatttgttcc tttaatatac ttgaattatt
    11041 tcttaaagca tttaaatgca tttgcatcgt ccaaccatat cttgtatact cagacatcaa
    11101 atgtaattga atacctgtaa caaattgtgc aatttctgat aaatggaaat ccgtttttcc
    11161 tgctaaagct tttattaaca gattgtcgag tattttttca tctgctattt cataaaaata
    11221 agtattcaaa ccgtgatctg ctaatcgaca gccaatttga tgaaaatgat ccactcgttg
    11281 gctcaatgct tgcttcaacc cattaaagtc tttgattggt atagccgctg cttgactaag
    11341 ttttaaaata tagttcgaaa agcctgatga tttgatactc cagaccttat ctggacggaa
    11401 agtaggtaat accttgaaag aattatcctg tttagaaagc tcagtatgat accccaagtc
    11461 atctgtagga tcatccgttg tacagatggc tttcacatcc atcatctcca acaattcttt
    11521 cgggcgatag gaatccgttt ggattttttc gttagcacgt cgccaaattt ctggtgcatt
    11581 cttctcagaa attgtcaaat caatatcaaa gtaacgttgt aattccaaat gagaccattc
    11641 aaaaatagga ttacctggcg ccttctccac tgtttttaca aaagctaaaa atttttcata
    11701 atcatcacct ggaccactga tcaactcttc ttctatacca ttagctcgca tcaatcgcca
    11761 tttataatga tctccagctc ctttatcatt taaccatacc tgagtcaaat tcttgtattg
    11821 cttattttct agcaaatatg ctgggtctaa atgacaatga tagtcgataa ttggttggtg
    11881 ttttgcaaat ttatgaaaaa gtcttttagc tatttcattc tctaataaaa agttcttatc
    11941 taaaaacata tttaaacact cctttccttc cgttagtttt tagaagagaa aatttttcct
    12001 ctaaataaac tccattatat aattatttac tcgccccctt ttcaagcgct tcccaaatac
    12061 catttaaata aactgcacct agagctcggt catataatcc ataaccaggt ctaccggttt
    12121 ctccccaaat catccgacca tgatctggac gaatatagcc attaaatcca ttatcgtaca
    12181 ttgtttttaa tatcttatac atatctagag aaccatattc tgatttatgc ggcgcttcgt
    12241 aaaaatcgag tccattgtca cttaaatatt tgatattacg aacatgtgca aaaggaatcc
    12301 gatcccgttg acaaaattca gatagaattt catagacatc attatctggt cgttctgcaa
    12361 tacttccagt acataatgta ataccattag aaggagaatc cactacatta cacaaccaat
    12421 ctaaatcgtc acgattttta acaatacgag gtaatccgaa aatggaatat ggtggatcat
    12481 ctgggtgaac tgccatttta atcccaactt cttcacatgt cgggataatt gctttgagaa
    12541 aatatgcaaa gttctctcgt aatttctctt catcaacttc tttataggct tctaataatt
    12601 gcttaatttg tgataaccga tgaggttccc aacccggcaa ttcaaaatta ttagtagaat
    12661 tttctacttt tctaataatt tcctccggat cagtagggat attttttgaa atataggcta
    12721 acgtagaaga cccatcatct aaacgataat ccaaatccga ttttacccaa tcaaatactg
    12781 gcataaaatt ataacagata acctcaatcc caaattctgc caaattgcga atcgtctgtt
    12841 tataattctc aatgtattga tctcgtgttt gtaaaccaat tttgatatca tcatgaacat
    12901 taacactctc aataactttc aaggtaagtc cattggcttc gacttcatct tttaaagatt
    12961 taattcgttc tctcggccaa acctctccgg ctggtatatc cattaatgtt ccaacaattc
    13021 ctttcattgc tgggatctga cgaatttctt gtagtgagat tttttcttca tttgccccat
    13081 accatctaaa agtcatttcc atagttactt tcctccaact tctgttatat atttattgat
    13141 tgttttacga actgcttgag gacctactag catttcgcaa aagatttttt cagttttctt
    13201 tcctacccca acttgatata aatctaaacc aaaaatttct ttattttcta aaatttcctg
    13261 taccgcacaa tgaatatttg aaggatcttg ttcacctaat ttcaatactg ataatttatc
    13321 ctgcaactct accaataacg gatcaggact tggcacaaaa ttttcccctt gatcatcgac
    13381 tgccagtaaa taacgtaacc aagcagcaat agcgatagga ataaatgtta gattttctgc
    13441 atttccgtct ttttcgacat actttttaat tgtttcacca tagcgaatcg ctactttttg
    13501 agaagtatct gttgcaattc gttgtggtgt atctggaata tagggattag gcaaacgttt
    13561 attaattact tcatcaataa attgttttgg atcaataatg cctggatttt caactactgg
    13621 taaaccttct aaataaccta ttcctttgat taaaccaacc aaatcatcat cctgcatctc
    13681 tgctgaaatt gattgatatc ctagcagaca acctgttact gccaaagcag tatgaagtgg
    13741 attcaagctt gtcgtaacct tcatgatgtc tgctttatca accgtctctc tatctgtcat
    13801 aatcacacca gccttttcca atttaggccg gccatttgga aaactatctt caataactaa
    13861 ataatgaact acctcagtat tagtgaaagc agcaatattg gtatgttttt ttgtgtgaat
    13921 gatatctaaa tcctcgagcc ccatcatcaa tagatcttcc tttacattct ctgaaggatt
    13981 tggcgtaatt cgatcaatca tactccaagg aaaagtcact ttttctttat cctttaaata
    14041 agcaataaat ttttcagaaa catatccttc tttttgccaa gcttctgcaa tcgtaaaaat
    14101 actatcttga aaacgttgac cattctgtga gaaattatca gtagaaacca tcgcaatcgg
    14161 caactctcca gcattaaatc tgctatataa caaggatgtt acaatactca tcgtatgttg
    14221 aggattgcta ggtccagatt tgatatcagc tttgactacc gaaaagaatt gccctttaga
    14281 atcttttaaa ctgtaacctt tttcagtaat agtaaacgtt gtaaactgta atttaggatc
    14341 ttcaaaatat ttaaccactc tttgatagtc cgctatattc ttcggattgc aatataaact
    14401 atcagccgtt actgccaaaa gccttttttt gagttcacca tctccactca taacaatttc
    14461 caaaatgtca ttgttgtagt catgataagc tttttccact acttcttcat caaatgtttc
    14521 acacacaact actcctgttt ctaattcatt ttgatctgct aagcattgag caatttctgc
    14581 atgaaatcct cgataaagat ttcctccacc aaaatgaagc catactggat gttgctggcc
    14641 ttcttgctta acttctttga catcaaaaca cggcagtaga atctgcattt cattgaattc
    14701 ttcgatagaa ttttgccaat ttttaatcga aaccataatt aacctcctta aactaatatg
    14761 ttagttttga tacattttat attttaaaac ccgttgtaac cgttgtcaat ataaaaatgg
    14821 aataaacttg ctttttttct accatatcag aattattgta ttttttattc agaaaaataa
    14881 aatactcctt ctttttggac tgattttatc gaaacttatt tttttctttt tttcatgtat
    14941 tcttttattt ttataactag tgtattactt caaaatttga tattatatgg catgaacaga
    15001 attaaaatat cagctaaaat aaaagttaag gagcattgag tatgacaatt aaaactagtc
    15061 tccaaaatca agcttaccaa tctattcgcc gacaaattat ctatgctgac ttagaacctg
    15121 gaaaaaaagt atcagaaaaa aaattagaag aaacactttc tattggtcgt acaccaatac
    15181 gtgaagcact gattcaactc cgacaacatg gtcttgttga tacaattcct caaagcggaa
    15241 attatatctc attaattgat ttagattcgg ccaaaaatgc tcgatttgtc agagaacatt
    15301 tggaacgaca aattatgtta gagtgttgtg ccaaaattaa taaccaaaaa aaacggattt
    15361 tagaaactat aatttcagaa caagaaaaag ctgttagtca aaaaaatgct cgtagttttt
    15421 ttcataatga taatttattc cataaagctt gttttgaaat tgcagagcga gaagaagtat
    15481 ggcaatggtt agaaaataac aatacacact tagaacgatt tcgttggcta cgagtaaaaa
    15541 cggaaggatt aaagtgggaa aaaattatgg aacaacatta tcaactattt gaggcattaa
    15601 caaaacaaga tccagaagaa gctaactttc taacatcgtt gcatcttcat ttaatgctta
    15661 atgagcaaaa tattgtttta gctactcatc caaaatattt caaaagtata taacttttaa
    15721 ctctttttaa attaaatgat tgttctgatc agaaaaatat cgcttgtttt cttattatgt
    15781 aatatatttc ataaactatt ctgcataaca actattgttt gtacttttta cattggataa
    15841 ctaattatga ctgctgataa cttttgatat taaactagta tctccaatcc aaataaaaaa
    15901 tagatatctt gttcatcaaa attagttcat ggatacttac cttcatttac atcattcagc
    15961 ggtttctcat tttcttttat tctattattt cattttctaa tagacttggc ttcatttcgc
    16021 aatacttttt tacaataggc atcaaattgg tgttgtttag atatttagtt gtagttttgt
    16081 gacatgataa gtatgctcct ttttgtcttt tccactaata caacgatcaa agggtgcttt
    16141 tttcaaaaaa ctagaaaaat caaaataaga ttcgtatttt gattctatat atcctgtttc
    16201 aactacatct tatatttcat aatagaataa atagcctttt gcatagctgc ttaacttata
    16261 agaaattgca atttacttct tcaaagtgaa aacgaatatg agtaaaataa aattattctt
    16321 cttacagata attaaaaata gcgcgtaaca aaaatcggca ttcaatcaca taattaggat
    16381 tgatgccgat tacttatatt ctacgtatag ttttagtatt ctttttttat caccagtaac
    16441 caattgagaa cagtcctaaa gcagaatagt cttttatctc aaaacgctta atttcaggct
    16501 taggaatatg aataatcttt tgagtatatt ctttctcttt taatcttact gaagaaatac
    16561 cactgcctat cttttttaca aatatttcat ttggtgtaca gactaataaa acaatatttg
    16621 taatcaatcc ttgcactaaa gaattaaaag gaagactatt taaaacaggg tgtgcataac
    16681 tataatatgt gaagtagtta ttttgaactt taacttttaa aaactttaaa aataatctta
    16741 tttgttcttc taaacaatca tctatactca tataatcact ccactaatta cttcccccaa
    16801 caagaaatag cattaatagc tataccagct gcaatagttg cagcattgaa ttttgcaaat
    16861 tgtgcaggag ttaaacttct ttttgctaca tctaaaagta ttttaacagc ataatcataa
    16921 tttttccctt gcaacgcatt aattaaagtt tgcattagat tttcacgatt aagtatatcc
    16981 caaacaacac accaaatggt aatgagttca taacaacaca tgcagcatac ttttgaagat
    17041 cacgtttttg acgctttcct gttggctgca caaaattttc taaaataaat ttccctgcta
    17101 taccttcaga gccatctaat tcagcttttt tctgtatagc ttctaaatca gtaactatat
    17161 attgatgtgt ttctgtatca acataaccag cttcttctaa atagaatttc aaactctcta
    17221 ctgcctgttg tctttgtgtt tctatatcag gaacttcatt cactttttca gcagcataaa
    17281 cactggttcc ggcaccgact aacgtactta atccaattaa cattacacct aataatgaaa
    17341 aaaacttaaa aaaacgactc atttttatcc ctcctgaaaa gtattgttga ttatcaattt
    17401 ttatcctttt aagctgttca ataagacgtt tttacgttcc ttccgtttct attttattct
    17461 ttctgtctta taacagcttt tttcaagtaa agaacgatat aattcttctt aaaaaacagt
    17521 ctattttttc ggtatataat aaaattgtat tgttacctac atagcgaaac agtaccaaca
    17581 tcattcaaat gaagatagca aatttgcttc ttcctttttc ttaagtgact atttaaataa
    17641 ccagaaaaaa actaaaatca cactgatatc ccaaataaat tgaaataaag gaaaaagttt
    17701 ttttctacca tgatagtttt tcaaaaaata gaaactcgta ctatttaaaa gtaaaataac
    17761 tagcatcgta aagactactg atttatctaa acttctataa aaaagtgggc taaataataa
    17821 agtaattaaa aaatgaacta tttgatattg ttttttttca tattaacaga tcgcagctcc
    17881 tgcgattcca taggctgttc ctacagcaaa tggaataacg gctgcaccta ctcccgtaag
    17941 gcttaaacct agagcagcag ctgtataaat cccagaatgt agaagtccag ccccagtgaa
    18001 agcccaactg caggcacttc gttcaccagt tttattattt gttttttgat ctttcatata
    18061 attctcaact tcatgaagct gatcggttag ccatccatgg ccattttttt tgaatagaac
    18121 gattaaattc atttagatac tgttggattt cagaaactgt aatttcagaa ttaattctat
    18181 ctaaacttga ttttaaatca ctctcatcaa taatatatac taatcgattt cctttagaat
    18241 ctttatgtgt ggctaaatta ttttgaatga tatttatttc agtttcttgt tgttttacta
    18301 aaaaattatt tgtttcagaa gcatcgacac ttattccagc gctaacaaaa gtacttaaac
    18361 ctattaagaa aacacctaaa ataccaaata ttttaactat tcttttcata atttttccta
    18421 cttaaaaata agttattttt aaaatatctt gattatgaat tcatccccca aaggcctttt
    18481 aagattgata cagcagtccg ttcacttctt ttagacttgt catataagtc ttttaaatga
    18541 tcccatacca gactagtttg tctatctagc ttcaatccat taaacgctaa tgaacggttc
    18601 attttttcta ttactttaga taaagctaca gaaattttta taccttcaca acgcgcatct
    18661 tggatttcaa taatagtatc atcaattagt ttttgaattt ctttcctatc aacatattca
    18721 atcttagaaa gagaatcttt taaagctact aatgattcaa cgatttcttt tttctcttca
    18781 gacattctct tcctccttct agtgacccgt aaagccatgt agagcagagt ccattgaacc
    18841 agtaattaca ctatctacaa cgccattcca atttactcta cattttccat ttttcagatt
    18901 tgtcggtcca tacggataga ctttttgaca ttcaatgttc ggattatacc agataggatt
    18961 ataccattca gccgcagaag cagattcagt cgatacaaac aatcccacac caacaaaacc
    19021 aatacacatc acactatagc caattaattt tttcatctcg tatccatctc ctaaaaaata
    19081 gaatagttct tgtagttatt cataagacat attttttccg tttttgtttt atcctttctg
    19141 tcctataaca acttttttca agtaaagaat gacatacttc ttcttaaaaa aacagtctgt
    19201 ttttttctat tttttcggtg cataataaat atgagtgttc attttttatt ttaatacaca
    19261 cttcgtacat aataaatctt gatcgcatca atcttttgag cttcttgatc tactttcaat
    19321 tgaagtaata caaattgagt gacctcattc gttgtttctt ctccaaataa caaatattga
    19381 tccggattct ctatatcttg tgtcacctgg tgaagtttcc cagttgtttt catttgtaca
    19441 tgcgggtcta catcaatact attgtcttta atacaacgat ccgtcatata gtccctcaca
    19501 gcttgattgc gtttataaac atctgtgaaa ttactccatt ttctagcaaa atcttttaag
    19561 aaattttttg tcatttcatc tatttgttgc gctgtctcgt cttctaatga accaatttga
    19621 ctgttacttt cagtactttg aagagttcca cttgtttctt ttactgcttc gattgtttct
    19681 tctgtcgttg tcaattgtgt tttttgtttt tcagaagaaa accaatgaca accagtaaga
    19741 cctatcaaac ataaccaact aaatactaaa attattcctt ttttcacgct tctagacact
    19801 gcctttctta tttcacctta cgaaccagac tacgaatttt tgtttgattg tacgtgcgtt
    19861 gataccgagc cataatccgt ccttgctcgg cattctgttc cacactagag aaatgttgtc
    19921 cgccatctga aacatctgtt ataattccgg tgtgaccata gattccagga gacaatgcac
    19981 cacctgcttg ccaattcacc acatctcctg cttgtaaatc acttggtttt gggttcatga
    20041 tcacttgcca accataggct gtccaatcat aatcttcccc tattaacatc gcaaacatgt
    20101 gtccagaacc cattaactgt gggccaccta gttgggatac ataccacgcc gtgccaccat
    20161 aacactctcc attatttacc gatcgtccaa tgatccgatc taaaactttc gcattacctt
    20221 tacttttccc tgcaacaagt gacgattttt ttgttggtag gctattccaa tgtttgatcg
    20281 caaaagtatc atattctgtt aagttataag actttatgat actcatcgct ccttggtaat
    20341 acggactgcc ttcggtaata cctgccgccg catagcctcc acgacctaga atcaataaac
    20401 aactcccagg atctttattg cccacacatt gattaaagtt gctttgactc gccaccaaaa
    20461 agccgtaata gtcataacaa tctttcaggt tcggaaactt catatagaag ccaccttcag
    20521 aaccaccaat cccccgtgca gaaccttgtg gatagggaca accaggaaac caggtaatcc
    20581 caaagaagtt tgtatcgttt cttccagatt gtgattgtcc ataagtcgat tcataaccta
    20641 attgagaaag aatcacactt ggtaataact gatactttac cgctgcaccg actgctgctt
    20701 gcgcatgttc atctgtgatc ggaccacgtc ctttaatctc tgaaaaaatc ggtaatcctt
    20761 cggtatattc ccaattaaaa gcgacagcta gacctgtagc ctctcctcca tcctcggaaa
    20821 gttctcctga aaaaaagaat ggcaatagaa aaaagggaag aataaagaaa agcagacaac
    20881 ctagacaccc tttcttcatt tcttcctcat cctttcttcg ataatggttt ttgaactgtt
    20941 cgtccttttg gtaaagtaaa atcggttcct ggttttgcgt ccaaaatcgg caatgtttca
    21001 tttttctttt ctattttttt cgattgctct actggattat taaaagaaga aaatgcaggt
    21061 tgtaaggatt ttggtacgga aatcgacggt ttactttcag acgaacgttg tatctgtcgt
    21121 tgcacagaac gatttcctga tagagtggct accgacgact taggaacaga gtattgattc
    21181 aataactgct gcattgctgg ataactccca tttttcgcct gatttttcac ttggtgaatc
    21241 tgttgtgaaa gagaaccagc agctgttaat tgtggcacgg gtacttttcc agcaggcaac
    21301 ggaatcgatt gaccaacaaa agcgatacct ttatttaaca atggttttct ttgattattc
    21361 ccttgttgct tactcgattg tgccaacgat tgtacctgtt gtttcggtct tactgaattc
    21421 atggacgaat ttggaatcaa accatttgaa agaccagaat tccactctgt ttttgatttg
    21481 gtagaagaca tttcaggctc taccccatga taacgaacat gacgaccact ataaggcaag
    21541 tcttgatttg aacgcccacc tagttcaaag ggattaatca cttgcccccc ttttaccgat
    21601 tcttgtggtg tacgtttttg ttgaaacttt tgaaatccat gtatcgctgc agaagcgagt
    21661 ggattcgttg ctcggtacac attccctgct aatcctgcac ctttgattgc caaattttgc
    21721 ccagcagttg atagttgacc aggcagttgt ttcatttgag acaaagaatg acttgctatg
    21781 tttttcgtgt tatttatggt ttgatctgca gctcctaacc ctagtttctt taataaatct
    21841 ttccgtttta caatgagtaa aattgatagg agtgctttga caaacatatt tcctaaaaaa
    21901 ccaaaaacag tattcattag aattaaatcg tctactatgt tatagatcaa aaatgccacc
    21961 aaaataatca cactgtaaaa agatttttga aacatcaagc tcaaaaagga ctttaaggta
    22021 ttcatgatca tataatcaaa tgctggaaca aaagaagcga gtaatgaaaa aggaatcaca
    22081 agtaataaac acaacaccaa catttgaaag ataaaacgaa tcatgccaat cactacaagt
    22141 ggtaatccaa tacttagatt aagcaatggc accatagaac caacgactgc tttataaaca
    22201 gctttagttg gttgaatata gacacgataa gccttctttt tccctctatc ttctcctgca
    22261 gcagtggtca cttttgtctc aatatcagat aattcttcac ttgacgcttc cttggctaga
    22321 aattcttgtg gttcaatctc tgcttgatac aattcttcta aatttgttgt cccataattt
    22381 aacaatagat acggatcaac aacagccgct ttataataaa gttggcgcac tttttgaatg
    22441 gcttcctttt gtgtcgttgg cactaaaaca ccattgacat cttttgtcgc caattcatct
    22501 agactatttg tagcagaaaa aataaagcct tctacctcca cggacaaatc atttaaccct
    22561 ttagtaaaag cttctccttt actaggtacg ttactaccat agccaaacca aaccattgaa
    22621 aaaatgacaa caaagagaaa tcgaataaac accatttttg cgtaatgttt ccctctaaat
    22681 atacgaagag taaatagata taacacatac aagacgacaa tccccgcacc aataggatcg
    22741 tatattttcg aataaatagt atccgaaaaa gtgaaaaact ggtgaattaa ctcgttcatt
    22801 gcagctcctt catagagctt ctcaatgaca aaatcaaggc cttgccaaat caatttactt
    22861 aaactaaaga acatattcgt catcattttt agaaaatctg tgccatttgc tccaaataac
    22921 attttgccta atgaaaattc actatcagat aaataagaag aaaaggtatc aatatgaaat
    22981 ttcccgatct catagatcga ttgatccacc tgtttttcta ccgcatatac caatccacca
    23041 acaaaaaaca gtccgaatcc aaccgttaaa aaaagccaaa cgcaccattt cttttcctta
    23101 cgctttatat aagccattgt ttcacctcgt ttctattgca tgattaacgt atcctgttct
    23161 tctatttgag agtgacttgt tttttccgtt gtttgtaatg cagcggtcat ttcttcaaac
    23221 aaactgtgta cattgagttt tcctacacgt ccatagggat ctaacatcca acactgtcct
    23281 ttaatcatat ggctcatttc agataagttc gcttcattta cttccaaacg taaatgagtc
    23341 aaaatctttt ctcgctcact gtcttcatca aaagcgaaga caacaccaaa attccctttt
    23401 tctttatctg aacctaagtc gccaataaat tgtgtatcta gcactaattg attcatctgt
    23461 gaacgcccca cacgcgccat tgctgcaata atactacgtc ccgcgttcga attattaaat
    23521 acccatgctt ctgtaaaata aatcgctgtt ttcttactac tatctcgttt tccaaacatt
    23581 tcacaaaaac gacctaaact aatcatcaaa cacaaagact ttcgatccgc atctgtatat
    23641 agttctggtc ggacattgtc atttggtaat ttcaaatctt ggatctctaa aatcgttgtt
    23701 ttggcattaa agtctaatcc cgggttttct ccataagaaa atcctaaacg taaaatcgaa
    23761 tcttctaccg tcaagcgtaa aaactcacca tattctcgaa cctctttttg ttccatttgt
    23821 tctaaatact cgaccacatg catcaagcca acttgttgtc cggcttcttt ttgaactaaa
    23881 acttcttgga ttccctttaa taccgcccct tttaaaaggt gattggtacc taacggactt
    23941 aactcatcaa tcatatcctg ggctacttgt ttcgcatcta ctcgggataa acaaacaatt
    24001 ggatctaata cgccataatt acggggattt gtagcatcta acgtgacata actcattttt
    24061 tgcaaatgtt ccacaaacaa agggtaatgt ttctgataat acgggtcttg aatgagtttc
    24121 gtaaaccatt tgcgcttttc tcctttggga tccacaaata aactttgtac attcataaac
    24181 gaactataca aaaagagcaa tccaactaaa aaggtcttcc ctttaccggt ttttccagtt
    24241 actgctacat gaggcgcatc aaacaacgca cctttgattc cttccgcaat agctagaaga
    24301 ttcaaaaaga caaaacgatt tgacgcataa attaattctt ctaatggtgt tttttctcct
    24361 cgagaaccac catcccctaa tgtatcttgc cgaccaatat accagccgga ttccatacct
    24421 aattctgata ctgctgaaaa caaccattcg ccaattgctt ctacagttgt tcggtgcttc
    24481 caatgcaact gtcgacccaa tggttgccct aataaacatt tatagaacaa ttctcgttga
    24541 tcattttttg cacggtggat atggatagtc gtatgaagct gttgaataat cgttgcacta
    24601 ttttgacgaa cttcttcaac cgtttgaccg tatacaataa aacatgcgat ccaatcgacg
    24661 acaggttggc cattatctac tcgttgcttt aaatgtttta ctaatccccg aacagttaat
    24721 aagcgttcgc taggttcttc atcgttttga accaattcct tatattctgt tttgaaccgt
    24781 tccgatagcc aatttagttt taaaccaata cctccctgtc ctttcaagcg tggatagtga
    24841 attttcattc gtaattctgc tgggaaagaa agatcctgtg caaattgaaa tagatcacag
    24901 tttctcatat tttcaggtgt ttctccaata ggtaacaacg ctaaataact agtccccaac
    24961 tcatcttcta attgaagaag gcctttatgt tccttcggca tacgtacata cgttccttga
    25021 ttgtctttca gtacttccca attattttgt tcttctactt tatgagccat tcctcgaata
    25081 tattgcagac gattgagata caacagctct ttttttacta agggacgaat agaaaagcta
    25141 taaagtaatt gtgtcacttc ttttacataa ggatcacttt cagaaaacaa agtttctaaa
    25201 tcatctactt ctaatccaaa taagcgtgct aaacttcctg ctacatctaa ccagattaga
    25261 tttagtacat cataaaaact ctccacggtt gctttttctt tgactttgat tcctaaaata
    25321 aaggaaggac gatagacttg accttctcgt tccaacaatg tcactgtttc ttttgcataa
    25381 tacgcaccaa ttgcttgact atcgggagaa aatccctttc ctaatgtgtc aaatttcgtc
    25441 cgtaaattca ttgttcgtgg atacatcacc aactccacat cttcataatc tgctaaaagt
    25501 aacagtaaac gagccatcat ttcttttatt tcctgtgtct tttttggtgt gttttttgaa
    25561 atggttcgtg gaaaaacatg atagtaggcc cagatacaat cctcgccatt taacaaacaa
    25621 tttttcttta atgctttcac tggttctttt acaagtacca atagatctca cctcccaatt
    25681 aaaaaaagga acaaccagtt gattgtccct ttttctaatc ctctaaataa acatacttat
    25741 tcgcaaaaag taattcttcc aatgcattat ttgatacctt gtcccagtta taatacacac
    25801 aatcaccatt catcatacgc actacataac aaaaccaatc ccataaataa aaatgcactt
    25861 tttttccatc aggttttagt tttgccagtg ctaacacaca taaatagggt agccctataa
    25921 aaaaaacaac ccctgctggt ggaaaaaaag aaataaccca accaataaat gaacgtaaaa
    25981 ataaatattc aaagattacg accaataaaa aagttgctgc attgactaat gcaactggaa
    26041 atggaagacg ccaattgctt gtaatctgtt gtacgcgata aggctccgca taaacaatcg
    26101 aataatcgta aggttcccaa tccacttcac tatcctccta atccataaat aatttttcaa
    26161 tgattttacc aaacgcatca aatacacgcg ttggatcatt taagaagaaa tagactgcgg
    26221 cacctgctgc gatagatatt aatgcatttc ctacttttga tttcataaaa tttcgcaatc
    26281 ccagataaac aaccaccatt attaaaaaat agccaccttg cgttaatata aaatctacaa
    26341 ttcccttcag tgtcatttcc gttcgtctcc tttcctatcc aaccaattat gtgtgagttt
    26401 ttcaacataa tactgatttg tttttttcgt aataacaagc gtcatttgtt ctttttgtaa
    26461 aagtgacgta tcaccatctc gaaagacgac tgttgctttt acaataaaag tttttttcgt
    26521 ttctttataa cgcaatactt tcatctctac ttgatcaact ttagctgtct gattgagtcc
    26581 ttcaggttct ttcatcatgt atgacatatc ttttgcattg tttttcgcat acttatctaa
    26641 gaaatcttcc acaaatcctt ccacatcttt cgcttccgac gcatcaaccg tttcgtataa
    26701 tgtgtcatca taagtaatca ttcgttgttt ttctgtattc tttggtagtg ccgtaaaata
    26761 aggataagca ataatacgac agcccttgtt tgaaatagaa aagggaagat tgagtacttg
    26821 tgtgattgtc acacttgttt ctttcttatt ctctggatcc atcgagcgaa tatcataagt
    26881 tactttataa ctagctgttg gaatggtttc aatttctttt aatccaataa acgaagcagc
    26941 agttaatttt cgaatacctg aaacacttcc tggttcttga ataaagtttt gtgcataaaa
    27001 ctcttttttt aatatttctt gacgttgttg ttcttgttca tgattatcga atgtattcat
    27061 atacaaagca acaaaacgat tcataaagga ttcaatttca ggtgtgtacg ttaattctga
    27121 ctgactttgt acttctttct tttgtaattg ttggatttca tctttcaaaa acgacacttg
    27181 aaccttcgtt ttcatggatt gaaaaaatgc caagccccct gaaaaacaaa gaaataaaac
    27241 caaacaccaa atccatttca ctgctttttt tgaatggatt ttcctttgat tcggtacttt
    27301 ctctgtataa actttttctt tccgccgtag ttgtcgtttt ttcataagct actccttcta
    27361 gtatgttttt actagtacgt acgattgaca acgataagct tgtttttctg aaaaatagtc
    27421 cattcaatta ccctcatttt ctattccttt tctctttctt ttatatccaa caaatccagc
    27481 aatacttgtc aacactcctc ctagaacaga aagtacaaca tgtatttctt caccagtctt
    27541 tggtaagact tttgtttttc catctgctgt tttgacttca atattgccac ttggaagttt
    27601 ctttacagga atcgacaaat cctttaccaa attcccttca ctatcttgga ttaatggaat
    27661 tccatctttt acaccaacaa ttgtttgtcc accttctgct tttagtggag ttgttggtgt
    27721 tggaatatgg gtcaattcct ctacattact agtgacaatc ggtacactca ttccttgaga
    27781 attattcgtc gtaatttcac cgtttggggt taccgatact gtgacttctt ttgctggaac
    27841 aataggttta ttttcttttg gaattgcttc tgatttttca gcaggttgtt tcggttcttc
    27901 ttttggttct tcactggtaa acgacatcgt tggctgttcc gtacttgacg aatcggtatt
    27961 cgtttcagaa gaactggttg ttcctgattg ttctggagtt gtgactatac ttgaatccgt
    28021 tgttgttgaa ctgtgcacac cttcttcttc aattggatca gtcggcaaag ttgattcagg
    28081 aatctctggt tctggtgcca ctggctcttt ttcaggtttc tctggctgca aatgttcagg
    28141 ttctgctggt ttttccgttg ttcctccatt tagctctgtc tcaacatctg ataatccttc
    28201 ccctggcaat gtttctacaa tttctgactt aggtgtttct acagtttcat ctgcataaac
    28261 caatgaactc cctaattgaa acgaaaataa tgaaattcct agtgttgtta cgactgctaa
    28321 tgttgttttt ttcatgatta ttcctccaat tttttatgca attcgtgttt tgttcataga
    28381 cgccgcacta atattatctg aacgataaaa gaactcccgt ccgttttctt ctaacccaac
    28441 atatggatta tttttgaata attgaatcaa tagttcactg gtgttgtatt ttggatagtt
    28501 tgcaaaaaaa taatactgtg cttgtcgccc atccgaaaat tcaacaagta attcataacg
    28561 ataccgcttc aatccttttc gttgttttaa aggatctcta taccaacttg tccatcgttc
    28621 cgttcgtgga ccgagataga cacgatacac atagaacaat gccataccac ataccaccaa
    28681 aaataataat cgccacataa aaattccccc ttttcttcta cctttcttga atcaccgaac
    28741 attcataccc tcggtagaga tccgaaaaat ccatcattaa tttttcgtat aaacgttgtt
    28801 gcaaatagcg attgtttcga atacataatt cttcatagcc atcaatcact tgatcttctt
    28861 tctcatagca tcttgtagct ctatgacgct cagcttgcat gacataacca aactctgcac
    28921 catatcgttc taccgttaat aactgttgac tacgcaataa tgcaatataa caatcacaaa
    28981 aatgttcagc cgacatttga tttttctcac gtttgtgaaa taggtattct ttagaaagca
    29041 cattattcgt taaacaatct gataaatagc gataatctgg cggtcggtta ttttcatctg
    29101 tgaatttttc ccataataaa ctgattttta ttcgttcagc ggctagatag tcttgttcgc
    29161 gtggataaaa ttcatcaatc gtacaaagct tttttatcac ccgaataaac aaatccatat
    29221 aatgcgaaac gaactcttcc ttttcaattg gctctcctaa aaattccagt gacataccat
    29281 cttctccttc cttaaaaaat aaaaaagcag aaaccgattt ggcttctact tttctttcct
    29341 tttatagctc ttttttacgg aagaatccgc aaatgacatt ttttcaaaaa attaatcggc
    29401 acaagttcac gaaaacttgg agcaatttta gatagaatca cttccccatc ttgtaaaata
    29461 caatcataaa aatcatcagt tacttgatac ttacgcttct tacaataatt gataaaatag
    29521 tagcgatcat tttctatttc cattcgttgt tctactaagc gcatacgaac atcatcatag
    29581 aaataagcca caaatcgccc ttcaagttca cgtttttcaa tgggatactc ttttggtaac
    29641 aatctatttt ttcgtcgttt atacattgct ggatacctta gaagaagttc atccaaacgt
    29701 ctgtcagtat atggcaactg acgaatcaat gattccaatc gttctttata cagatagaat
    29761 aattggcgca agcaatagtg tactgcttct ggattttcta atactgttgg atcacgcgac
    29821 caatacgcac caacataaat cataattttt ttcatttaga caatcacacc agcaatacta
    29881 atcaccgatc cacaataggt agaacaagtg gcatagcggc cgatttcctc taattccagc
    29941 tcaatctctt ctaaagaaag atacgtctgt tcttctgttg gctggcgatt catttcccaa
    30001 gtaacagttg ccaacgagat ttcttccaca agaggttttt cgttgctaag tgctgccaca
    30061 cagttttcgt atatcttcat tttatcgcag ccttttttta ccgctaaaat cgcaggtacc
    30121 ggcaatgaaa atcgataaaa gcgaatgaat tttagcgttc cttttcttcg gctaaattcc
    30181 aactcttcga gttcttgttc gtacccctta cgaacttcta ataagcgtgc aatttcttgc
    30241 cagttttctt tttcctgata acgtccagcc tttaccgctt gttcaatata aggaactcga
    30301 aaacgaaaat aagacaaatc aaccatcttt tcatttaatg cttcaattgc agcctttaaa
    30361 tccaaaagac gcagccattc tgttgtcgta tatgcattca tgcaattttc cctcctgacg
    30421 ttcccatcca ttctagatag ctttgttgct cgtcatttag ttcagcattc tcaattcctt
    30481 cttgtacaaa gtctcttcct aaaatacgat ctgcttcttg taataacttt aatgtcggag
    30541 ctacttgttt caaaaaccag cgttctgaac gatctaatga gaatttttct ggctttacgg
    30601 taaaatccaa ttcttccatc gaacgaaaca attttgccca tcgttcatca acaattcgtg
    30661 catcactttc cagtcgatcc caaacaataa gttttgcatt aattaaacca acgccaatct
    30721 ctcctaaacg tttaggggaa tgatccaaaa taaacgcttc tactgcttgt gttgcttttt
    30781 cattagctag gcgtaactca tatcgattat aaatgccata tttcgttaat gcttctattt
    30841 ctgaaatttt ctcacgattc gcaatttcaa aacgtttttc gtagaaattg aaaaacaatg
    30901 gactctttcg cgatccaaaa tacaaggata acccttcgct tcggaaataa ccatcatcta
    30961 aaaaacaacc gccaatattc tgaaatttct taaagtccat ttctaataaa cctgcttttt
    31021 gtttttctag taattcaaag agatcaaaat gttcttctgt ttccaatccc caaagttcat
    31081 ctaacgcaat atcgaatcga ctacattgta ctcgtttata accagcttcc aactttcctt
    31141 gatttttcca aatggaatat agccatgttc gccaatctgt tcgttgttca cgcatgactt
    31201 cctcatattc tcggcaacct tgacccgaaa actgtacaag tacattttgt gttacagttt
    31261 gttttgaatg ccagaatacc cagatatttc cacgaacaga aagacaatca aaaagataca
    31321 agcccgtcgg acgtgtttca aattctgtta gatccattcg taacacacgt tgaatcacta
    31381 ttttgtagtc tgtcccaaaa aaggagagac gcaaatagtc gatcattgct cgaagatcta
    31441 ttccgctttt catatacaat cgaaagcgtt ccttgattcg tttttcgaaa tcctctggga
    31501 ttttcttttt tccttgttcc atcttcttta tataatctac cgagcatccc aataactgtg
    31561 caaaacgttt ttgagagagt aattttttcc ctccacctga agcgtgaata gcactcaatt
    31621 tttttcgata atttcgcaat tcaataggtg tcatattcta cctcctttat aaaataacaa
    31681 atttcgattt tcttaatctg ctagaaatcc cgatataaca ggtggtaccc cctaattttt
    31741 ctaaaaagga gtactccttc taaccttagc taaagccttg atataactga tttaaataca
    31801 cttttttatt tgtgttatgt tatttctgcc ccccatatta tatatcgggg ggctttacac
    31861 aaagaggccg tgcgcaagcg cacgacctct ttgtgggcac acatgccaag catgtgctgc
    31921 cacgactggt ctcggtggct tcgccgacac aagccgcggc agcacatact cggacaatgt
    31981 gttctcccat agtccctatg aaagccaccc cgatatctaa accaatgaat cttctttttc
    32041 ttgtaattct ttatactgtt caggagcaaa acactgtaaa atcgctaaac gtaactgtat
    32101 gtttttctct ttgcataacc gatatacctg acgaaaacgc aatatatcct cttttgtcaa
    32161 aacaatctga tttctcgtaa caaacaatgt ctcgcgctca attcgtcgga aaacataaga
    32221 accttttgtg tagtattcta ctttgttaat ccactcgtat aatcttcgaa ccgcaaaatc
    32281 aggtgaaatt tcacccgcag ctgaagaaac acgatacaaa acttcaccca tacttcacca
    32341 cttccttcta aattataaaa gtgtataact ttcctcatct accccatttg ttttcgtatt
    32401 tccttttaac gattgcgctt gacgatcaat ttgttcttcg taactagtaa acgcctcttc
    32461 tttcagtaca gaaaaatctt gcacaatcat tgtgtcaaat tttttaaatt cctcaataaa
    32521 gtgatagtct ttgtaaacaa atggcgcaaa gaattctaca ggcacatcaa aaccaggaaa
    32581 agcataccca cgaccaggtt gatctttgtt ataaaacggc ttattcttaa aatcctctcc
    32641 aaaagtcatt aaatagccaa tgggagataa acggccaaca gaaatacgga acgttaaact
    32701 atctcgaaca ccacttggaa aatattccgc atctggtcgc tgcatcgcta aaataacata
    32761 catgcctgct tgacgacctt ttaatactaa tggctgaatt aatttatcaa ctttgtttct
    32821 cgtttccata tccaacgaac catagaaagc tgcccattca tcaaaaaaga taaaatgcgg
    32881 cggtatccca taataagcat aatttttccc tggttcatac ttaggctctt tcatcgtttt
    32941 catataggta tatcgctgat tcatttcttg taacgcattt cgtaagcaaa taatcatttc
    33001 ttcattcgtt ttgtaaaaca catgtccttt gaatacatca atatcaccta atgccgctaa
    33061 atctgccgct ttcccatcgc aaatatctac tgtccctaca tctaaacaag ctttgatcaa
    33121 tgaatacaat aaataggttt ttccgccacc aatcgcacca gaaattaata gatttggcga
    33181 ttgatcatat acccaatcca atgttttcat taaatgaata cgtccatttt ctgctataca
    33241 ttgatcaata ggaatccgac cagaatcgga aagaaataca taattgattc gggctttttc
    33301 tcgttcttca cgaattaaat cacgcaaaaa tacttcggat aataagctac ccatttttaa
    33361 aaatcgttcg tggaaacggc caccatctaa aggaaaagaa accactaatt cttgtttctt
    33421 ttgataaaaa taaacttttg gtaatctcat tttttccttc gtttgtttct caccaacttg
    33481 cttctttgta taaacaaacc gattgtcaat taacattcga gcaagtaact gacgccaata
    33541 aacagaagca aaatatcctt cctttagtcg cgaccaacgc atcaaaccta aaattaatcc
    33601 actaaccagc aacaaataca tcacaatact gattccagga ataagataca tttgccaatt
    33661 cgaatacgta tttaaacgag gataaaatac tttccaacta aaccaactta atagaatcaa
    33721 aaatggtaac agaaagaaac cataataaca aaaccataaa taacgattga aataacgaat
    33781 tcgtcgacca cgatacttaa aaaaatgagg ttccaattgt cacattcctc ctttctgttt
    33841 ttacttctcc tgtgctaaaa atttttgaca aaaagcaact aatactggaa tatcacattt
    33901 aataaaaaac cataatcgaa aaagatttaa tcgattttta tatgggtgtg cacacatatt
    33961 acatattcgt actacacgaa tccaaaccac ttcctgatgg tcttgtttcc actgatacgg
    34021 taatgaaaaa cgaacaagat cacgtaaaaa catacactgc ccaataaccg cacaaatata
    34081 ctcatttgtt tgtataaaaa tcgttggatt gtctccaaaa tactcaatca attgttggat
    34141 attttgacaa caaaccataa tctctcgaag tgtttgattg gttttgtcca gattcaaaat
    34201 ctccccttcc ttctacctta aatagaaaga gtaggaagac ttcctcctac tctttaaaaa
    34261 acttattttt tctctttttc cttagaatca gcacttggtt gtttttgatc taaacctttt
    34321 tcttgtgatt gtttcggatt agaattattt gttggagctt ctactttctc taatcctttc
    34381 gcataaatca ctaaatctga atattcacga ttgccatctt gtgctggaat atataccaca
    34441 tgatattctg gatcaattaa tttcacagga tcacgtcgtt taaaaccagt caaatctaca
    34501 tctgctggaa atttaactcg tcgtgcaatc tttggttcat ctggatttcc aaaaactaat
    34561 tgtgctcgct gtgatcgaat ttctcccgta taatcgcctg tttcattatc aaatacacga
    34621 tcggactctt ctaatgcgcc aaagcgtacg gctcctatac aagtttcatc taatgcttct
    34681 gtaatatcat aattatttgg aaattttaat cccatcttac aaaacctcct caatttttac
    34741 accagttaaa aagacaccga catcttgata gccagttgtt cgacgctctg tttgtcccat
    34801 atcatttgtt tcacgactat tcactctttc tttacgaaaa acaaaataag cttcttcaaa
    34861 tgaaatacgt acctcttttt ctggtaatcg taatctttta tcctcttcag ctgtgagata
    34921 aacaaaaaaa gcaggctgtt cttctcgcga acattctgct tgtaattgaa catatcgccc
    34981 agacacacca ttaatttcct ttggtggatt aggttcccgt gaacccaata aaaatacctg
    35041 acctaaaaac tctttcttca tacgcaatgc tttttctgcc atatcatttt tcctcctctt
    35101 aaaattcaca atcaattcta aacgactcta tattacacaa tggaaagtaa tgtttaacaa
    35161 caaatggctc atcactagga gacatatcta ctattaacat cccgtctcgt tcatgcacag
    35221 aaatatcagt acactcctca tacgtacatt cttttccact caaaaaacaa atatttatat
    35281 ttttcttttc catattcttt tttcctccat tattttcttt tctgtaaaaa ccaagtaata
    35341 attccttttc catcttccaa cacaaactga tgatatattt ccctagcaag aatccacaca
    35401 catgctaaaa taaagaaaat aataatacta ctaaagatgc actcatcctt gctgtcaaac
    35461 ggaaaaagat atatcataat tgcctccccc ataattaaga aaccaattga tacaaacaaa
    35521 aactctacca tcatacaaaa gaatatttct tccaactctt ttacatcctt tctaactttt
    35581 tataaaaaag gagattattt ttataaacac ttttattcaa caactatttt caaatgaatt
    35641 acacattatc atctcaagta tagtttcaat cgtcactatt gtttggtcca tttctagctt
    35701 ttatttaaaa catcgctata caagaaaaaa gaaaagcact gaaaccctaa caaaagaaat
    35761 gtttattcca tttaaatctt caattgaaaa ttatctattt caaaaaatta caagaaaaaa
    35821 tattctagaa cgaaaacaaa caattcaaca tctaatccaa acagttgaaa ataaaaatat
    35881 agacttttat ttgccttatg aacttattta ttttgccaaa gaaatacaaa aaataattaa
    35941 cacaaataaa cattcgaaaa aaatcctctt caaagtacaa agaatgtatt ttgaattctc
    36001 atactgctac ctagcagaac taaataaagt aagaaagcaa ttaggagtag ctaaacgtga
    36061 tttcttctat agaaaaaaag aaactgtatt atcacataat tatattctat ctcttttgga
    36121 tccttaaatt cttatttatt acactcagta tttcttggtg tatcctcatg atcatttact
    36181 actcaacaca ataatttatt tgcctttgat aaaaaattct ttctaaaaac taaacaagcg
    36241 gctagttgcc taaccgcttg ttcgtcctct ttagtctctg actttataca aatcataacc
    36301 aatcaatcct gccgcaagga caaagatcat accaatcatg atccataata cattgtcttc
    36361 agagcctgtt tttggcaaca taggtaccat tgcagcttgt ttcacttctt ttacaggttg
    36421 tggttcgttt ggttttactg gttgcggtgg ttttggtgcc tccacaaatt gaaccgtttg
    36481 atctttgttt gttagatcga cgttatgttt tgcgacttct tcaaacgttt ctttttcatc
    36541 ttctgttttg gcttggagcc attccgcaaa actcaatcct tttcctgcaa ggttgcgacc
    36601 gtcaacgatg aattcaaaca agaattccat catttcttta tcagccataa agactttttc
    36661 cgcatgtgtt ccttcaaatg gggtgccgtc tggtgttaag tagccttgaa caatcagttt
    36721 gtaaatttga ccgattgcta acccattaac ttgaacccat tcgacaacct tttgatttgg
    36781 taaagctaag atctcttttc caccatttgc attggtagct tttgtcgtaa tggttggact
    36841 gacgattttg atggtttggt ctttgtcggt aatatctgcg tgagaagcca ataatacgcc
    36901 ttctctaaac agatcttcaa aaactacgac ttctttgctt cgcaacgcat gtgcgtctag
    36961 gataaagtct agattgactg taccatcagt tgtttctgcc acaaacgtta aggtacttga
    37021 gacttctttt ccatctacta gcactggttt ttccgttact ttgtccatta gaacaccgtt
    37081 gactgtgtat gtttttccaa cgatcaaatc gtggtatttc acagcgtctg taatggtgac
    37141 tttcgttaat ggattaacct ctttcaagcc agtgggttta tgtgtagccg ttgtacgtac
    37201 acttgggttc gttactcgta ccgtttgacc tttgtcgttg atgtctttat ggtttgctag
    37261 ttcttcgtca tttctaaaaa gactttcaaa cacgaccatt tcacgaccat ttaaacctgt
    37321 caaatcaaag gtaaatggta cgatcaccgt ttcattttct gctttggcaa taaagccaac
    37381 agcactttct accggttgac catgaacaag taaggcttca ccagttgctt tatccattaa
    37441 gattcctttg accaagtaag cttttcctgg aaggatctca ttaatttcaa cggtatcatt
    37501 taaggtgaac agccccgttg ggtctgcgat cgtcaacccg tcttcaaata cagctgtggt
    37561 atgaaccgtt ggattgttta cccgaacact ttgattgtca tcattgatat ccacatgtac
    37621 cgcaacttca atgccatcac ggaaaagttt ttcaaagaca acgattgttt gacctttcag
    37681 aacactagca ttaaccacaa attcaagatc ttttgtgcca ttggctttgt ctgcaataaa
    37741 ggtcaagata cttgtgattt ctttgccttc ttgtaaaatt ggcgcattcg ttgccttgtt
    37801 catcaataca cctgaaatag tgtattcttt gccgacaaac aggttggtat aagaaacact
    37861 atctttaatg acgatagttt ctaatggatc aaccactttt tcaccatcgg ctttatttga
    37921 cgcttgtgtt tctaattttg gtggaatcaa atagttacgt acagaaacca ataacgtttc
    37981 cccatcatct ggcgcatttt gtctgaatgt aatagtgaat gcttgtttgc ctgtatttgg
    38041 ttggaaactt tctaatggta cattttcggt aaagtaatag ttattggcaa ccagaccttt
    38101 tactaaaatc tcaccatttt gatcggtggt atatttacca attgcttgac cttttccgtt
    38161 atatagcgta aacgtcacac cggcaagtgg tgttttcttc ttgttccatt cttcatactt
    38221 gaacaatttt acacttttcc gtgcttgacg gttcgcaaaa tggatcactt tgatcggttc
    38281 tgtatcattg gtaatcgaga acactaatgg gttttgattc aaaacgtaat ttacgggtgc
    38341 tttgatttct tccaaacgat agcgctcttt tccataagta agtgtaccgt tagttaggaa
    38401 aaagcctttt tcattggttt taaagatatc cgttgtttct gtatcatttg gaatctccat
    38461 tgtgacataa cgattggcta aagtatcaaa aatcttgaat tctgtattgg caagtggaat
    38521 cacttttcct gtttcttgat ccactttcac cactttaaga cgttgttcaa ttactttatc
    38581 ttctaaaaca taatggaaag tttgcccatt ttcagaaatt gtgacttcaa gtggttcaaa
    38641 tagtttatac ccttcttttc ctttggtttc agaaagaatg taggtatcaa agacaacagt
    38701 atttttacca aaagtagcgt aaccatcatt gtctgtcaca acggttttca ccactttgcc
    38761 agttgttttt gacgtcaaag agatttcaat gccagctaat tttggtttgt tatctggatt
    38821 ggttgaatcg actaaatctt tattagcaat tttcactaaa tcaatggttc ctttgatcac
    38881 ttgatctttt gcggtcgcat tgacagtttt tcctggttca acaacaattt caattgtttc
    38941 atcagaaagt gcatagcctt tcggcgcttt gatttctttt aaaacatatt tgccaggatc
    39001 aagatcttta atttctgcct gtactttgcc gttcatattt ttcaaggtaa tttctttgat
    39061 ctttttccca tctgcttgat acaagccata caccgcattt tctaaagaag ctgcgccttg
    39121 tgctttcaca ccggtttctg catcttcttt aaagacacga atgtttccct gtttcaaaat
    39181 agtcaaattg acaacagagt caccaggttc aaaaggattc aatataccaa ttgtttgggc
    39241 acctggacga cgatacgcta atggcgtacc caatacttca atctgattga aatgaatttt
    39301 tgccttttct ggtgcttctt ttgtgactgt gatccatgct tcattcccat gaatagatac
    39361 attgatccct tttggctttt gaatgccttt tacacgttgt agaaagtcat tgccactttt
    39421 tacttttaac gtttcgccaa tttttatcgt atgtgtttga ttatgaaaag tagctcttac
    39481 atcaaaatta ttaagcagac gttgaatttc tgcttttcga cgatcataat caacacggat
    39541 atttttgatt gggatttttg tgcccaaagc ttcccaaatc ataaattgtg ccgcaatgta
    39601 ttgttcatcg gatttgtctt tatttgtgac atatcctaaa taagagatca agcttgtttt
    39661 tttccgtaca tttgaatttt tcaaatagtt ttccaaagca gtagctgtat aaacttgacc
    39721 ttctgcggct gagacaccag gctcaataca aaacgccact tgtccattaa tctcaaaacg
    39781 aaccatataa tttaaagtga agtttggatt gttcggacta gaagtaacac caatattttc
    39841 gccccaatca attttccgac cacctaaaac agctgtattg gttgcacggc gaacacgaac
    39901 cgaacgattg gttggtactg ttactaacag tgtaggtgta cctgtttttg gaatgtcctg
    39961 ctcttttttc ttttgatctt caatactagc cgtagattct ttgtttagtt tcgttggttg
    40021 attttgacta gctgcggttg aagagattgt tttttcaacg ttttcctcat tttttccttc
    40081 tttgtcagca gtagccgctg gttgttccac tgtttcttct attcgttgct tttcttccgc
    40141 ttgtttctca gaagactctg gcttcacaga aggcgttgct tcggcagctt tttctccttc
    40201 tggagtggac gtttctgaag caggggttgt aattgaggca gtttcttcaa ctggttgtga
    40261 agtaacagga ctattccctg ggtgttgtgt ttccccaatc gtctgatcga gagtcgtttt
    40321 ggaattaacc gttggcgctt ctgtcacagg ggcctgttca acagtggctt caccagctgg
    40381 gaccccggct tctgctggtt ggacttctgt cacttcagaa gcgacttggg caatggcttc
    40441 caccgtaggt tgtgtagccg tcgtttcttc tgcatgtgct tgagcagttc ccaccaagaa
    40501 acagaattga gataaggcca ccaatgcgag tgctttcaac caattcattt tcgtttttgc
    40561 atacacaaga attcctcctt ttcctgagaa ttttatataa taaaacaaaa caccgttacc
    40621 aaaagtgata acgacgtgaa ctgtctcttc tatttttatc tggcgctctt atctgaacac
    40681 atttcatcaa tgattttacc ctcccactat aattacagaa caaaaaaaga acctgcttcg
    40741 tggaaatcaa ctgtccattt cccaattgga ataccagctt tattggcaac ttcaccatca
    40801 ccaaatatca tgccatacca attactacct tcatccttaa tttctttcca accatatgac
    40861 atagcttcat ctaacgaatc aaaaatcatg ccactgttgc caattgttgc aggatctggc
    40921 ttaagatctt ctggaataga aatatcaatc acaccataat gatccgattc cccagtatta
    40981 ttgtcattac tagctactgg tttggttgtt ctactgactt attttgatac aacaagtacg
    41041 cttattcttc ttttacttct ccgttttcaa tttcccattc aaaccactcc gcaaagtctt
    41101 gcttaaaacc atctactcga tacctatttt gtaaataggc atcttctgac gtcgtaggat
    41161 ctaaataggt aggtttattc tctggacgag catagacacc tacccatgtt tcgtaatctc
    41221 cttcaaaata actatctacc aaatagcctt tttttctaag aatctcccga acttgatttt
    41281 taattattga tacttgttca aaaccatcac tcattctatc acctcaaata actctagatt
    41341 ctcataaata ttcccgacaa tttcaatcct atcaatgatc tctaacaaat cgctacttat
    41401 gcttccccat tcgtataaga atttcccttc cgcaaaataa attttccata aacttcttca
    41461 tgatcgtccc aaccaatatc actctcgaca aattccacgt tgttcttatc ttttagctca
    41521 gtaaatgcca taagttcaac atgttttcca acctcgaaac aatcacacca cccatcaacc
    41581 gttacacgtg tgccttcaat acctaagaaa ctttgtcctc gtgtattaaa cactaaaact
    41641 ttccgcattt tttgctcatt aattaatcac gcgcgaaatc taggaatcac aacttgttcg
    41701 cttcttcttt ataaaataaa aaaactccaa taatcggaaa ttactatctt ttcctcattc
    41761 cttttttaaa tcttcatact tcttcttatc tttgtcctaa cctaataaca caaattttga
    41821 agaaaaactc agtaaaacct gattcttttt ttatcttcac aacaaccaac tttttcttca
    41881 gatcctttta ctagaacttg tatacaaaaa ttgttgaatg ctgatacaat ttgcggttac
    41941 ttgaaaaaac gatagatgta aaaagataaa tagaatcatt tttttattct atatcagtct
    42001 atgattcatt gcttatcaat cacccaaccc attcgatgcc gtttttttaa gagaaattta
    42061 aaaaagaccg tacgaatctc gcattgtccg attacttttc tagaaaagat ccccaattct
    42121 gtataaataa ccctatcttc ttgttggttt cattttctca tataagaatt cagtcaatct
    42181 acccactatg accattacta cgtccaacac aaccgacata ttaaccacgt aagtattccc
    42241 tcacagatct ccgaatttcc atggtatgga ttcccatcct gacgctgcag aggacaacat
    42301 atttcatgtg gctctgtacc cttttgattt ggaaagacta caaatcaata ctcatctata
    42361 acttatcaag cgaactttcg ctaggcttct agtgattact aaattgttgg ataacatacc
    42421 tagcccattt tatctagctg gtattcataa cagttatttc ttgtattact tcttccgctt
    42481 gtgttgccat tgagcttgtc aaaaagttac ttagaaaaaa gctgccagta aagcaacttt
    42541 caacaaaccc tttttgtttc ttatcatatc aagaaacctc cttttataaa tttttctata
    42601 ataaaaaaac gtcgataact taataagtat cgacgtaaac tatttttata tcccgtaaat
    42661 caaaaattct aaagaaagat ttcctatata agcatattgg ataattcgat tagtattggg
    42721 tatatctcta ccattctcat acctatctat ggaccatttt gaaattgaag gagaaaaaag
    42781 ctttccaaac tcctcccttt ctagataata atctttccta attttcctca tccttaatcc
    42841 catactaaaa gaatttatct tgttaaaatc gctaactctt tcatcttttg gaagtatatt
    42901 cttataatct tctccgtaca taaggtaagg aacagtgacc ttaccaagat aggcaatatt
    42961 cattagtttt tcaatatctg gaatattaat acctttttcc catctactta taacattttt
    43021 gcctgtatag atggtaaagt ttttaccaaa tttttcaagc gtctcttccc ggttctttcg
    43081 gacttctcgt attctttttc ccataacaat tttatcgtct tttgataaac taaatatctc
    43141 actatcacga ttactctcct tcgaaatttc tttttcatta cttaatagaa aaatatcgat
    43201 ttttttttgc atttcttttg acggatttct ctttctattt aacacataac tgagtaatac
    43261 ttcactaatt cctatattat cagctaactc tttgttaagt aacttattca tatctctgta
    43321 tgcaattagt tgaccgatga gaatctcaat cttatcttcc tcatctttta ttagagtttc
    43381 tatattcaaa atcttgctta gagtattatc tacgtcttta gggatttttc ttgacccttt
    43441 ttcatattta actaaagtac tttgtgaaat acctgctaaa tcagctaact ttttttgaga
    43501 tagttttttc tcttttctta gagatttaag aacccttcca cttgaattat caaccatgaa
    43561 aaaagcacct cctatgagat gctttcatca tatactgaca gctaaaaatc ttcaagaaaa
    43621 aatattccaa ttttgttaat tttagtatcg ccgtgataac caaatgacag tttaaaatct
    43681 tttatacaga taatcctcag tgttgcatct actcaaaaag gttgatttaa taggtttttc
    43741 gattgattat aagttatttc acactatctt gctcatccat tttcagaacg gccatgaagg
    43801 cttcttgcgg aacttcgacg gagccgattt gtttcatccg cttcttccct tctttttgtt
    43861 tctctaagag tttacgttta cgagaaacat ctccaccata acatttagcc aagacgtttt
    43921 tacgcaaggc tttgatgtct gaacgggcaa cgattttttg tccaatagct gcttggattg
    43981 gcacctcaaa ttgttggcgt gggattagtt ttttcagttt ttcaacgatt gcttttccac
    44041 gttcataggc aaagtctcgg tgaacgataa agcttaatgc atcgactttt tctccattca
    44101 gcaagatgtc catcttcact aacttgcttt tttgataacc agacatttca taatccaatg
    44161 aggcatagcc tttcgtgctt gatttcaatt tgtcgaaaaa gtcaaagaca atttcagaaa
    44221 gcggaatatt atagacgaca tttactcggt aatcatctaa ataatccatc gtaatgaatt
    44281 ctccccgttt tcgttgagaa agttccatta ctgcaccgac aaaatcattt gggaccatga
    44341 tctgtgcttt gacgaatggt tcttctacat cctgaatcgt tacaggttca ggaaaatctg
    44401 ccgggttatc tactgtagca gtcgtaccat ccgttttatt aacatggtaa ataacggatg
    44461 gtgcagtcgt gatcaattct agattgaatt cccgttccaa gcgttcttgg acgacatcca
    44521 tatgaagaag tccgaggaat ccacagcgga acccaaaacc taatgcttga gaggtttctg
    44581 gttcgaattg taaagcagca tcattcaatt gcagtttttc taaagcttcc cgcaaatcgt
    44641 tgtaacgaga agtatcaatt ggataaagac cacaataaac catcggattc atttttcggt
    44701 aacctggtaa agcttcagcg gcaggattgt ctgctaacgt tactgtatcc cctactcgtg
    44761 tatcttggac agttttgata cttgctgtga tataaccgac atcaccgacc atcaaaaagt
    44821 ctctagcaac tgcttttggc gagaagaccc cgacctctgt aacatcaaat gttttgccat
    44881 tactcatcag tttgattttg tctccgggtt tgaccatacc gtccgtgatc cggacattta
    44941 gaacaacacc gcggtaacta tcataaatag agtcaaagat caaagctttt agcggtgcat
    45001 ctaagtctcc acttggtgca ggaacatatt ccacgatctg ctcgagaata tcttcaatcc
    45061 caatccctga tttggcactg gctaatacag cttcactagc atcgattccg attacgtctt
    45121 cgatttcttg acggacacgt tcgggatctg ctgcgggtag gtcgatttta ttgatgactg
    45181 gcaggatctc caaatcattg tctaacgcta aataaacatt ggccaatgtt tgtgcttcga
    45241 ttccttgtgc tgcatcgacc actaaaacgg caccctcaca ggcagcaagg cttcgagaga
    45301 cttcataggt gaagtcgacg tgccctgggg tgtcaatcaa gtgaaagata tatgtttctc
    45361 catttttcgc tgtgtaattg agttctacag catttaattt aatcgtgatt ccacgttcac
    45421 gttccaaatc catcgagtct aacagctgat cttgcatttc gcgagacgtc acagtgtgcg
    45481 tcatttctaa aatacgatcg gccaatgtag atttcccatg gtcgatatga gcgatgatcg
    45541 aaaaattacg aatctgctct tggcgttctt tcattttctt tatatccata gcgtctcctc
    45601 ttttcatata atcagcactt tccattatac caacgaaaag cagtaattta aagagttttt
    45661 aattagtcag ctatagaagt tttttttgta gaattttgct atactgttat caagctaata
    45721 aatggagatg aaaaaatgga tcaaaaagat tttagagaaa atcttgaatt aaaaccggtc
    45781 actcaagaac atatcgatca attcaatgaa ttgctttcct atgtgttcca agtgactgaa
    45841 gcagacatcg aggaaagcgg gtttgagaat aaacgagctt ttatccgttc caaaaaaccg
    45901 attttggaag tatcgaaagt gttcggatgg ttccacgaaa ataaactgat ctctcaaatc
    45961 gctatctatc cttgtgaagt caatattcac ggtgcacgtt ataaaatggg tggtgtgact
    46021 ggagttggaa cttatccaga atatgctaac catggattga tgcaagatct aattatcgtt
    46081 gcattggata atatgcgcaa gaataagcaa tggatctctt atttgtatcc ttacagtatc
    46141 ccctactatc ggcgtaaagg atgggaaatc atgtctgata aactttcctt taaaatcaga
    46201 gatacacagc tacctaaaca aatcccagta agtggtatgg ttgagcgatt accagttgat
    46261 catccagacg tattttccgt ttatgacaaa tttgcccaac aaaaccatgg tgctttattc
    46321 cgcagtgatt ttcattggga agagtattgg cgtttcgaaa atgaagatga gcgcacagcc
    46381 gctgtctact acgatagcaa ccatgaacca agaggtgttc tgttctactg ggtagctgaa
    46441 gaaatatttc acgtaaaaga aatgttctat cttgatcaag aagctcgaaa tggcttatgg
    46501 aactttattt ccgcacattt ttccatgatc tactgggtac atggagatat ttataaaaat
    46561 gagcctttag catttttgat tgaagatagt cagatcaaag agcagatcga accatatttt
    46621 atggctcgga tcgttgatgt aaaagaattc cttcaacggt ttccgtttgt tggaacagct
    46681 gatgcttttc atttcatcat tgaagatcct gtcgctcctt ggaataatgg tgtcttcgct
    46741 ttaacatggg atgaacaggg acaagtccgt gtcttaaatg aacctatagg aaaatccgtt
    46801 cgactggata tccaaacatt gacttgcttg atgatgaatt atcgccgtgc ttcttatttg
    46861 gcaagaatcg aacggttaga aacagatgaa gaaacactga agtcactaga gcgtatcatt
    46921 ccaaacatgg aagcttactt tagcgattat ttttgataaa aaggatgatg tttagatgaa
    46981 aatttatttt gccgcaccaa tgtttgctaa aagtgatttg ttatataacc aacagttagt
    47041 taaagaaatc agagagctct cttctgagct ttcgatctat cttcctcaag aaaatgaagc
    47101 aatcaatgac aaaactgctt atgcagacag tcgaatgatt gctcttgctg acacagaaaa
    47161 agtgttggct agtgatttaa tgattgcttt actagatggg ctgacgatcg atgccggggt
    47221 agcatcggaa atcggtgtgg cttatgcgaa aggcatccca gtgatcggct tatatactga
    47281 tactcgacag caaggcggaa cccacccgaa aaaaatcgct gcactacaag aaacagctga
    47341 aaatcaattt cactacctga acttatatac aataggtttg atcaaattga acggaaaagt
    47401 ggtttcttca gaaattgagt tgctttcaga agtaaaaaga tttttagatg gagggacttt
    47461 cagtgattaa agaaatcaaa aaggtgcaaa tagctttact tgcttttggt gtattcgttg
    47521 tctgctataa tttttatgaa tttatcacac aaaaatattc gacttctcaa ggaatcacat
    47581 ttatcgtgga atctttatta gggattgcat tgattttcat gccacaagtc attttgaaag
    47641 ttttcaaact taaaatacca gcagcaatcg ttttgtttta ctggtttttc ttgttcatct
    47701 ctgtcttttt aggcacaggg atgcatttga tcagtatcat ctctttttgg gacaaaatct
    47761 tacatgcggt gagtccaatg gtcctgacag ctcttggcta tggattgatt ggttacttga
    47821 tgaaagatgc tgagatatca aaaaccagtc cttggttgtt cctcttattc ggctttgcgt
    47881 ttgctggact ttgcggcgtg ttttgggagt tctgggaatt cttatgcgac cagttcttag
    47941 gcatgaatct tcaacgtttt gctgcttctg atggcacact gtttgtcgga cgagcagcat
    48001 tgatggatac gatgggcgac ttgctgacaa atacgatagg tgctgcctta atgggattgt
    48061 ttgcatggtc tcaaagtaaa aaagatgagc gttactttga aagttataaa ttagaaaaag
    48121 tgaaaaatac ctaataaaag aggttgtgac agaagcgggc agcttcaaga aatttcggct
    48181 tatttttcga agaaactact tctggaacac tgtttatttg aaaaaaggag gtctgacact
    48241 agttgtgtca gacccctttt ttcttttata gtctcaatgg aagattagac gatttcttct
    48301 agctcttctg ttttgaaatg aagttgtcca tcaagtaaag taatcgttac ttttgattta
    48361 ggcataacat gtcctgcaac gatttcttta gctagtggtg tttctacttc cttagtgata
    48421 aatcgtttca atggtcttgc accatatgct ggttcataag cattttcagc aatccacgtt
    48481 ttggcttcat cactgattgt cagcaggatt tcttgatgtt ccagacgttg tgccaattgc
    48541 gccaccattt tgtcaacgat tcctttcacg ttgtctaggc tcaatggtgt aaataaaatc
    48601 gtgtcgtcga ttcggttcaa gaattctggt ttgaagtttc cacgtaatag cgtgttgact
    48661 tgttcagcca ctgcttctgg aatcgttcca tcagcagtca cgccttccag cagtaactgt
    48721 gaaccgatat tgctggtcat gatcagaacc gtatttttga aatctactac tcgccctttt
    48781 gaatcagtca agcgtccgtc atctaggact tgtaacaaga tattgaagac atcgggatgc
    48841 gctttttcga tttcatccaa caagacgatt gtataaggat ttcgtctgac agcttccgtt
    48901 aattgaccac cttcttcgta acctacatag cctggaggag ctccgactag acgagacaca
    48961 gcatgttttt ccatatattc actcatatcg atccgtacca tatgatcttc tgagtcaaac
    49021 aagttctcag ctaacgcttt cgctaattcg gtttttccga caccagttgg tcctaggaaa
    49081 aggaaagaac ctagaggacg atttgggtct tgcaatccag cccgtgaacg aattaccgcg
    49141 tcactgaccg catcaactgc ttcatcttga ccaatcactc gtttatgaag tgtttcattc
    49201 aatttaatta gtttttctcg ttcaccttct acaagtttcg ttacggggat acccgttaat
    49261 ctgccaacga cttgagcaat ctcattttcg gtaacggact cttgaaccat cttaatctcg
    49321 ctgtcttttg ctttagcttc taattccttc aattcttttt ctaattgagg tatcgtacca
    49381 tgacgcaata cagcagcgcg ttctaaatca tagttatttt ctgcatcttc taattcgtgt
    49441 tttgctttat cgatttcagc acgttttgct gaaacagaat tgacttcttc tttttctgtt
    49501 tcccactgca tcttcatcgc atttgcttct tcacgaagtt cagctaattc ttcttgcaaa
    49561 tttttcaagc gttttttact tgcatcatct gattcttttt tcagtgcagc ttcttcgatt
    49621 tccaactgca tcaaacgtct agtaacttga tctaattccg ttggcataga gttcatttct
    49681 acccgaatcg ttgcactggc ttcatcgatc aaatcgattg ctttgtccgg taagaaccga
    49741 tcagtaatat aacggtcaga taaagtagct gctgctacta atgcgttgtc atggatgtta
    49801 acaccatggt ggatctcaaa acgttctttt aatccacgca gaatactgat cgtatcttcc
    49861 actgttggtt ctttgactaa taccttttga aagcgacgtt ccaacgcttt gtctttttcc
    49921 atatattgac ggtactcatc taaagttgtg gcaccgatca aatgtaattc accgcgagca
    49981 agcattggtt tcaacagatt tccggcatcc atacttcctt ctgtttttcc tgcccctacg
    50041 atattgtgga tttcatcgat gaacaagagg atacgtccat cacttttttt gacttctttc
    50101 aagactgctt ttagtctttc ttcaaattca ccacggaatt ttgctccagc gatcaatgca
    50161 cccatatcta atgaaaaaat cgttttatct tttaaatttt caggcacatc tttgcgtacg
    50221 atacgttgag caagcccttc aacgattgcc gttttcccta caccgggttc tcctatcaga
    50281 acaggattat tttttgtttt tcgtgaaaga atacggatga catcacggat ttcttcatca
    50341 cgaccgatga ttggatccat ttttccgctt ttgacttgct gtactaaatc aacgccgtat
    50401 ttttctaatg ctttgtattg ttcttcttgg ttttgtgagg tcactctttc tcctcctctc
    50461 atctcttcga tgtttttacg caattctttt tcagataatc cgtttttatt caaataaaca
    50521 gttaacggat aattttttaa tttcatcaac gctaaaataa cgacttccgt tgaaagaaac
    50581 tcgtcgccga agctttcacg tatttggtct gcttcattca ataatcgaaa gaaattctgg
    50641 ctgaggtttt gtccatattg gacgtttcca ccagaaacaa ctggatactc atccagtaga
    50701 cgatcaattt catgttcaaa agattcgaca tccaatccgg catccgtata gaaatttcga
    50761 ccaaaatgat taggttgtaa aaagattttc catacatggg caatgtcgat atcttgatgt
    50821 tttcgagtga ccgcaatctg ttgagcttca gcaatcgctt cttgaagcgt cgtagtcatt
    50881 ttctcaatat tcatacaggt ataccctcct aattaaaggt aagatcactt atttctttga
    50941 tctttacaaa aactattata tcgctttggt caattttggt caaaatatac acatggtttt
    51001 ttgacttttt ttctcgactt atataaatct taaaaaaaca aaattgattg tatgtatata
    51061 aaaaaagagc caaacaaacg taaaattatc ttatccataa cgtttttctt tgatttgata
    51121 aaaagggtag atcttataaa agacctaccc ttgattttct ttattctctt tttttacttc
    51181 tattatttct tctttgatca ctcttcgccg ttcagcaatc acatacacaa atccatagag
    51241 aaatggcaag ataaaggaac tgaaacgata cagtaaaagc gaagaaactg cgtcaactgt
    51301 tccaacaact ggtctgaata ataacaaata gacaaattca aaggaaccaa taccagcagg
    51361 cgtaggaata acccctgaaa gcactactgc aaagctgata aacgaaatgg tcagtagaaa
    51421 atctatttta ggatggtttt caatcagaat caaataagga agtacatacc aaaatacaag
    51481 ttttaacata ttccatagat aaatccgcaa tagcgcagtc ctgtcttgga taatggtttg
    51541 gaccgtttcc cttaaagagt agatctgctg attgcatgta tccacccatt tccgcaaacg
    51601 ctcactttta aataacttat tcgataagct gacaaaaaat atttgaacat tcaagctgac
    51661 ggacatcgcc aataaaaagg caacaatcac gatcgtcaaa aggataccag cgatgataaa
    51721 ccagatcatt gatggaccat tagaataaaa aagagagaat tggatgacca agccagctaa
    51781 tgcataagtg atcactgcca gtttgtacat aatcatatgg agtgctgtca cccctgctcc
    51841 ctgggatagc ttcattcctt ttttgttata aaaataaatc tccgagatca gcgttcctgt
    51901 accaaacgaa acgattcggt aaaacgcaat atagctagag gtcaagaacc catctttcgt
    51961 tgtaaaattc ggcgcgaaag gttcagcaat ttctttgatt gagcgccctt cagcgatttg
    52021 gtaaactgtc cctaatataa cagccgctgc caaaacaaca acactggtag acagcaattc
    52081 ggcaaagata tctgcaaatg attgattgat taaataataa ataatggcaa aaatcacaat
    52141 cagcaaaagc agattcagaa tgattttagt tttcgttcct ttagacgaca tctcctgctc
    52201 cttaatggaa aaaataaatg agaatcaaat caacaagtac acctgcagcg aatcctatag
    52261 taaacttctt tttccgagtt ttatgatgga aaacttttcg agagatcaat cctcccaaac
    52321 caccgcctaa caggctgaca aatatcaaat tattctcagg aacacgccag ccgctagttc
    52381 tagcctgatg tttatcatac cccatcagac aaaataagta aaaattcaca atgaaaaggt
    52441 aaaaccacaa aagattgtgt aacaatacat ccattactct tcttccaact ttctgttaac
    52501 tactatttct aagctttttc ttctttcttt ggtgaataaa ctgttaatcc ttttgataca
    52561 acagataatt caactggaag atcatctgtc gtgtctccat ccgttcgagt gcccacagat
    52621 ttttcctgcg cttggatttt catgcgtttg gctgtgaaat aagtaatgcc ggggatcgta
    52681 tagaatttgc ctctcatgat tctaggcaaa taaaaaataa atcggaaaat atctaaggaa
    52741 ggtacgatcg ttacatgaaa ttttccatca tctagggtcg ctgagtcgtc aaaatttgta
    52801 aaaccgccca cggagttaga catcgtgact gtcaacagtt gggattttcc tttccaatgc
    52861 tcctcgtctg tttctaaatc caaatgatat tttttcttct tcagcaataa cttaaaaaac
    52921 ttcttgataa agatccacga gccgtaacgc tgtttttctt cttgactgat ccaaactgct
    52981 gtatctgcta agattccgat tgtcagtgta gagataatga cttcatcatt gacttgacca
    53041 tagtctattt tccgtacatt gccttccagg atcacgtcag cagcttcttc ttttttgagg
    53101 ggaatctcaa gaacacgtgc aaggttgttg acagttccac ctggaagtaa tccgacatgg
    53161 tattgagata atgttttttg gaacgcttgg acgatatgat gaatcgtgcc gtctccacct
    53221 ataattacta aagtatcagc ttctatggct tctgctttct tgactaattc cgcatcatca
    53281 atcgatgggc cagtttcagc tagttctaca tataattctg gctgcttttc ttttacataa
    53341 tcttgaaacc agcgtgctaa tttctcaccc tcatctttcc ctgaactttt gttataaaaa
    53401 actagcagct tttccattct ttacctccta tttactcttc aaaaaagagg gcgggacaac
    53461 caattccatt gtcctgccct ttagccttag acagatgaca ttccatcatt gggacgaacg
    53521 ccttgtcata agctgttctt tttcgatttt aactctttgt gttcaattct gcaattttta
    53581 caatcacgtc tgttgctttt tccattactt gtaaagaaac aaattcgaat cgtccgtgca
    53641 tattttctcc tccggcaaat agatttggcg tcggaatacc catgtaagag atttttgaac
    53701 catctgttcc tccacgaact ggttcgatca ctggagagat accaagctcg atcattgctt
    53761 gtttcgctaa ttccacgatg ctcatatctt tttcaatgat ttctttcatg ttgtaatatt
    53821 gatcatacat atctactttg attcgttctt gatcaaatcg ctgattcaac tcttcttgga
    53881 tatgtgtgat ttgtgctttg cgtgcttcga atttttcacg atcatgatcg cgaatgatat
    53941 aactcataga agcttcttca ggattcccat ccaatgccat caaatggaag aaaccttcgt
    54001 atccttccgt tttttctgga acttcatcgg ctggaagctg attatgaaaa tcgattgcta
    54061 actgtagagc attgatcatt gtatcttttg ccgtccctgg atgtacattt ttcccttgga
    54121 tcgtaatatt tgcttgagca gcactaaacg tttcatactg caactcacct aaaggaccac
    54181 catcgactgt ataagcaaaa tctacatcga attgctcaac atcgaattta tccgctccga
    54241 caccgatttc ttcatcagga ccaaaagcca ctttgatggt accgtgaggg atagaaggat
    54301 tattgatcaa gatctccatt gcagtcatga tttccgcaat ccctgatttg tcatctgctc
    54361 ccagtaatgt actgccatct gttgtgatca atgtgtggcc ttcataattt ttcaaatttg
    54421 gaaaatcttt tgtattcaat gtatagcgtt cttccgcatc tagtacgatc gtagactcgc
    54481 catcatagtt ttcaatgatt tgtggattga ctcctactgc attaaaatct gctgtatcca
    54541 tgtgggaaat aaatccaatg gaacgcactt catgatcaac attgcttggt aatgttccca
    54601 taacgaatcc gttatcttca ttatagaaaa catcagctaa gcctaactct tctaattctt
    54661 ttttcaattc ttgcgcaaaa gcaacttgtg tctgagtcga tggagtcgtt ttgcttgttg
    54721 catcggagcg tgtttctgtt ttgacatatc gtaaaaaacg tggcaaaaga ttttcgtaca
    54781 tagtattctc tccttttaat taaattgaaa tgggtttgta tttgtttcag aaacgaaaaa
    54841 gttaatatcc caattttctt cttgtttcca agattcaaat ttctcgataa atcgttgctt
    54901 gcataacgat tcaatataat gaccgggatc aattgcaatc aacccagcgc tttgcatatc
    54961 atgagccgta tgataataga tatctcccgt gatatagaca tctgctcttt gggcgattgc
    55021 ttgcggataa aatttttcac cgcttccacc gcaaatcgca atgcgcttca cagaggattt
    55081 tgcatttttt ggctggacta ttctcagtcc atctagttgg aacgcttctt ttacttgttc
    55141 tacaaatgcc tctatagaaa tttcttgcgg caattcacct actcgtccta acccaaacat
    55201 ttcgactggt tcatctatag cgaaaagatc ataagcaggt tcctcataag gatgagctga
    55261 ccgcatggct tgaatcactt gtttttcgat agtttccggc aaaataacct caacttttgc
    55321 ctcttgaact tgttctgtct tccctacttt cccaatcgct ggttgtgcac cagcttccgg
    55381 agtaaatcga ccgtgtccaa tcgaggtaaa acttgtaccg gtataatcac cttgtgtacc
    55441 agcaccagct gcagctaata cttcacgcat tttctgtgca tgatccacag gtacataaac
    55501 ggccagtttt ttataatgaa tctcatgagt ctttactaaa taactctcca cttcaatacc
    55561 gagaagttca caaaaccagt cattcagtcc atcccaaata atatccatgt tcgtgtgtgc
    55621 tgcatagacg gcaatatcat gtttcaacaa atctgcatac attttttctt gtggctgatc
    55681 agtaaccagc cgttttacag gacgaaagat tggaggatgt ttagcaatca gcaaatcgat
    55741 ttttttcttg attgcttctt cgaccacttc tggacgaacg tctaatgtca tcattactcg
    55801 ttggattggc ttatccaatg ttccgatatg cagtccgact gggtctcctt cttcagctag
    55861 ccactgagga caatagcttt caaacttttg gatgaaagtg cgtccgctga ttgtcatggc
    55921 tttaaaacct cctcaatcat ttggatttcc tgctcgattt gtttttgacg tgcctcttga
    55981 ttagctgctt gtttgagctg ttcacggata gcttttcttt gttgaagctc tcttgtccat
    56041 tttgatttga agatctcact tttctcttca agcagaaatg gcccgaacat cagctccatt
    56101 tcattgtaag taactggttt ttgttctttt tcggctacaa tgatttcata tattttttta
    56161 ttttcttcaa gtattttttc tgattggatt ttatactgat tttcttgcag ccaagatcgt
    56221 aatgtacgct ctccgatgtt tggctgaagg atcaaacgtt cttgtccgct taagcgttga
    56281 ttcaacttgc cagcttctag gatatctcgg atcagtgaac ctcccatacc cgcaatcgtg
    56341 acagctgtaa taccatcttg tggctggata gcatctagac catttgcaag gcgtacggtg
    56401 atacggtctt ctaatccatc ttttttgact tgcttacgtg ctgattcata aggaccttga
    56461 acgacttcac cagcaactgc atattcgatt tttcctctta atatcaatgc aacgggtaag
    56521 taagcgtgat ctgatccaat gtctgctaaa cgagcggatt cagggacaaa gtcacccact
    56581 gcggctaagc gctgagataa atctaaatgg ttcatagctt cactccttct agataattat
    56641 agcattttcc aaataaaata aggagactag gaataaaaaa attcccatat ctccttaaaa
    56701 aatatacctt ttcgttctat aaaacaacat tttcttattt ttgaaaaaat gttattggtt
    56761 atttgttcaa tgaaacatca ataatcgaat ctccaggaac ttgcggtggg atagacatcg
    56821 tcatgatcgg catctcaact aatgtaaatt ggactttgtc accgattttc aattcattta
    56881 tgtccacgct tattttttca gcaatagcat ttaagatcac tccgtcattg ctgaatgacg
    56941 ttcccatatt cgctggatct tctttggcca tgacatcgac gagtttcaac tgaagcgttt
    57001 cttcttctgc ttctacttga gtaatacttt caatcgttcc gacaaatatg ctttgtctct
    57061 ccgttttcgt actgcttgtt tttactgttt gacccgcatc aatcgaatca acagaacctg
    57121 tgttgctatc tgcgctaccg cagcctgcta aaagaaaaaa tagaccaact acagatatac
    57181 tagaaaaaat agccctcata aaaaatcctc cgtttaagtt tctgcattac ttgttgcggt
    57241 gattgtctcc ggtcatttct gtccatataa tgattcgctg acctgctttt actactaggt
    57301 caaatgtcag ttggacttgt caactgttca accattgcgt cggttgcgac cagtcatttc
    57361 gatttctttt gtcaaataac gtatgcgttc cattatccgt ttcgctttta gcggctcttc
    57421 atctccacgt tgagtgacgg acaaatgctg ttccaattca tccattgtaa aattcgatga
    57481 gaagaaggtt ggtaactgtt cctgcatccg atattgaagg ataacaccga atacttcgtc
    57541 tcgtatccaa ctactcatcg catctgcacc aatgtcatcg atcatcaaaa taggtgaacg
    57601 tttcactgca tctaactttt ctgccacttg atcttttccg attgcctgtt tcatctcaac
    57661 ggcaaatgtc ggaaaatgga ctagcgtcgt ggtgaatcca gcaatcgcta attctctcgc
    57721 tgttgctcct aataaatatg tttttccaat accaaaactt cctactagat acagtccttt
    57781 atgataccct tttggatcag cagtatattt ctctacaaaa tctagggctt ctaagctcgc
    57841 atatcctcgt ccatctgtac gttcaaagtt ttcaaaagaa gccgattgaa tatcttttgg
    57901 catatccatt gcttttactc ggcttctgat ttcttcttgt ctttgccgtg ctaacaatgc
    57961 ttccgttggt acataagtga catccacata atgaaaattc aacgtcagct tcggctcata
    58021 gccgggagcg atcatcgttg gatcgttttt ttgatattta cgcttttctt gcacgaattc
    58081 atacaattta gcgtaacttt tttcaatatc cgcttgtgtc aattcttctt ggtgtgcgct
    58141 tagaaaagct tgaacatccg catcatttaa gacttcagcg atcatttcag catacttttc
    58201 ttgataattg cgtttgctga tgatcctctt caattctttg cctacgtctt ccactagata
    58261 tcaccctcct tttttgccag gtattcttta aaacggcggt caatctctgc ttttttctcg
    58321 ctgctgatct gtttttcatc ttttggctgg ttgacccaat caggaagctt ttcccgtcga
    58381 acatttcgct tgccagtttg ataatttgtt tgcttctttt gttttgattg ttttgcttga
    58441 ttacttattt gccgaatgtg ctggatcgct tcttctgctg tggcgatttt cttttgtgcc
    58501 cattcatttg ccactgtatt tacataactg gcatttaagc tagcattatt cttgatcact
    58561 agtacataat tcagcaaaac attgatcacg ctactggaaa gacctgattg agaaacaaga
    58621 tcttgcagta accagttttc ttgtttagaa acatatccgc ctttttctga cttgattgct
    58681 tccagatatt tcatcggtgg aatgctctgt gcttctttta tcagctgaag cgctgcgttt
    58741 gtcaaatgtt cgtttgacga gggttcatta ctgttttcag aaaccgcaac tgtttctttt
    58801 gtttgcttca ccggacgtct ctgcattgcc aaaatggctt tttgcagttc tttttcagat
    58861 actttttgtt cactaaagtc ataagattga ctgatcagtt cgccaagtgt caattcatcg
    58921 aaaccgtaaa gctgatgata catgtcgact tgtttgatga ttggatcatc aagacttgca
    58981 atatgttttt ttgccagcca atcattcaaa aactgccaat cgaatgtcga atctgcttca
    59041 agtaatgcta ctgattcaga ttcttcaaaa gatttattca gcgattcgat gttttcttga
    59101 ttagcagcgt acactgcttc attgaagcga taaacatcta aaaatttttt tgtgattttt
    59161 tgatatccct ctgctgtatg ccttttaggt tcaaagaatt gggtaagctt ctggaatcgt
    59221 cgttcaccaa ctttttccag aagaagaaaa gccagaacag agtctttgaa aaatgcttta
    59281 ggaatgagtg gttctaacag ctcataaata aaacgaggtc ccagatcact atcttcttta
    59341 aaataaacat ccagtaagcc gattccttct agcttttttc ttgcatcata aaattgcggg
    59401 ataccgcagc ctagactact aagcagatct gcatgcatcc cttcaggacc tttgccagat
    59461 tcttgagaga tttctgataa cagggtgaaa tagatactca aggcttctcc gccgattagt
    59521 ggctgataaa gatacagcaa ggcgttcttg ctgtcttctc tcagcggagc cgcttttctt
    59581 ccttggtaaa tattttttgg ttgaagctct ttccaagcat tttccaagga aatgcctcct
    59641 ttttgtttct taattgtttt ctttattatt ctctttatta ttttcttttg ctttatccac
    59701 gatatcttgc aactctttta agaaaacaga catatctttg aactggcgat aaacacttgc
    59761 aaaacgaata taagcgattt cgtctaaatc aactaaatct tccatcacat attcaccaat
    59821 tagattcgtc gatacttcgt tttctccgag actgcgtacg cggttttcga catggttgac
    59881 gatttgttcc atttgttcca tagctacagg tcttttttct gctgaacgga tgagtcctct
    59941 taaaatttta tcgcgattga actcttcgcg ttccccgttt ttcttgatta ctaataacgg
    60001 agcagcttca attcgttcaa atgtagtgaa tcggaacgaa caattctcac attcgcgacg
    60061 gcgacggatc gcacgtccat catctgcttg acggctgtcg attactcgtg aattattatg
    60121 ttgacatctg ggacatctca ttttgtctca cctcttgcat cgcattttat ataaaggatg
    60181 tgtctttctt tacaactagt tgtattataa cacgaaacaa atcacaaacg cgactgtcct
    60241 acccaaaaaa cacggatata agaacaattt tttctacttt catgcgtaat tgtgtcccct
    60301 gtccttacta aatttcaatt ttccaatact gatcaccttg attactgaga aataacttac
    60361 acaaaagctg atttagtcat ctagcacaaa aaacttgaag cagatgaaca ccttctcatc
    60421 tgcttcaagt cacatctcga ttttttacta ttttataact tctcttcgat tcctgtatag
    60481 tgtttcattc gctgttcctc gattttttgc tcatcggaaa tgtggtcact ttctgggagc
    60541 ggtgttttac tacgatcagg tgtcggattt tttcgttctt gagtcaaatc ttgccgcttc
    60601 gcttcttctt ctgcctgctg gtcttctatt tcatcgattc ttgcttggta ctgcttttct
    60661 ttttcttctg ctgtttctga ttgcgtacga ccttcatcga ttagattttc tttattgagc
    60721 atctcgccga ttttttcttt tgcgttacct acgactttat ccttttgatt ttttaatgat
    60781 cccatcgcta tccctcactt tctatatact caggatagca aaattgacac agatactcaa
    60841 agaaagcgat tagcaaaaag ccaattttcg atttgtccca caagtttttc ttttgttcca
    60901 ttgttgtcga acaaaatatc cgcacgctgc tttttttctt cgattggaag ttgactacta
    60961 attctctgct gcgcttgttc tagcgtcagt tgattacgtt tcatcaaacg ctgaagctga
    61021 gtttctggcg tagtataaac gacagctact gcatccatat agtggtcata atgaccttcg
    61081 tagagcaatg ggatatctac aattactaaa ggatgattgg aacttagaga ggcgatttga
    61141 tcttttatcg cttttcggat aaacggatct aatagctgat caagtttttg ccgtttttcc
    61201 tttgatggaa aaacaatcat cccaagtttc cctcgatcta gttgcccatc aggctgcaat
    61261 acctcttggc caaacactga tacaattttc ctcagagcaa gcgttccagg ctcaacagtt
    61321 tctctggcaa tcacatcgcc atcgatcaaa ggaaatccat gagactgaaa gactttggct
    61381 gccgtacttt taccggtagc tattccaccc gtcaaaccta aaacaaatcc tactttgcga
    61441 tttttagcct ttgacaattc ggacaatagt gcgtccccct ttgtgccact tttgttttca
    61501 cgatcggcgt tccacaacgt atacatggtt tgccagtttg ctgatagaca tgcagtgcta
    61561 cttgaaatcc gcctgattct cctaatgcat tcaaataact gcgaatcgtg gtacctccgg
    61621 cttctattgc acgatccaaa acatcaatga tcgatagacg taattgttct acctctttgg
    61681 ggcgcagtgt gttcgccggt tgttctggat ggatcttcgc ttcccataat gcttcatcta
    61741 cataaatatt acctagacca gtcactagac gttggtctag cagcaatggc ttgattgctt
    61801 tgtgggactt tttcagtcca tttgcgaaat ctgctaataa gaagctatct ggcaaaggct
    61861 caggtcccaa tttcatgatt cctcggtaag ttgcacttgc tcctttttcg acgattgtca
    61921 tacgaccaaa ttttcgtaca tcgttgtagc gaagttggct tccatcctca aaaaagaaaa
    61981 gtacatgcgt atgtttatcg attggtgtat tttctttcgt aaattgatat tttccttcca
    62041 ttcgcaagtg tgagatcagt tcacaatgat cgagatgaaa aattaaaaac ttccctctac
    62101 gtccaatgga ttggatggtt tcgccaacaa gagaagcctc aaagatgggt gtctctggtt
    62161 gctcgatgat cttgggccac aagacctgaa ctttttgaat cgtttttcct actactaacc
    62221 gttccaatcc tttacgaacg gtttctactt ctggtaattc tggcattttt tcttttcacc
    62281 ttcattatat tgctctgtct taaacaatgt ttattttgct tcgtaccacg tttttcccca
    62341 actgctgtca gtgatcagtg gtacatgaag agaaacagct tgttccataa cttccttcac
    62401 caatttatct aatgattcaa gttctttttc cggtacctcg aagacaagtt catcatgaac
    62461 ttgtaacagc atcgtagctt gaagacctgt ttcttttaat cgtttatcca attcgatcat
    62521 cgcgattttc aaaatatcag cagcacttcc ttggattggt gtattgatag ctgttcgttc
    62581 cgcaaaagaa cggatattgt aatttcttga attgatgtct ggcagatatc gacggcggtg
    62641 atacagcgtt tcgacgtagc cttggtcttt tgcttcgcgt acgattcttt ccatatattc
    62701 tttgacacct gggtattttt caaagtacgt atcgatgtat tgctgtgctg cttttcggct
    62761 gattcctaga ttttgtgaaa gtccgtaatc agagatgcca tacacgatac caaaattcac
    62821 tgcttttgcc tgcctacgca tatttggtgt gacatcctct gccttttcga ttccaaatac
    62881 acgcatcgct gtgctggcat ggatatcttg accttctagg aaggcagctt tcaaatgttc
    62941 atcatttgag atatgcgcaa gtacgcgtaa ctcgatttgt gaatagtcag aagaataaat
    63001 cagccagtct ttttctctag gaacaaatgc ctgacgtatc tttctccctt catctaatcg
    63061 aatcgggatg ttctgcaaat taggatcaac agagcttaat cgtcctgttt gggtcaatgt
    63121 ctggacataa cgggtatgca cttttccatc tgattggatc actttcagca gtccctcgac
    63181 ataggtagat tgaatttttg caatttgacg ataggtgagg atatcctcta cgattggtgc
    63241 ttgttcacga agctgttcca gtacatctac ggctgtggaa tatccagttt ttgttttttt
    63301 gataacgggt aatcccattt tttcaaataa gatcactcct aattgctttg gtgaattcaa
    63361 attgaattct tcgccggctt cttcgtagat tttttgttcg atctctctta agcgagcaga
    63421 gaactcgccc ttcatttctt gtaagcgagt cgcatctact ttgatcccgc ttatttccat
    63481 ctctgccaaa atgatagaca atggcagttc cattttccgg aaaagatctt cttggttttt
    63541 atctgccagt tcttggctca attttggtgt caacgcattg attgcagcta cttttcgcgc
    63601 taaatgagca aaaaagagtt cctcttcttc tggtaaacct tttttcgccc ctttgccgta
    63661 tacagcttca tctgattgga tatcgttgta tccgtaatga gcagctattc cttcgatatc
    63721 tgtgcttttt tcattcgtat cgagaaggta tgcacctagc aagacatcaa aatcgattcc
    63781 tttcgttttt ccagtatagc ggtttaaagc aacataagtt cgtttcgcat catatacttt
    63841 tttcagccga gtcggatcag tgatccaaga atggaacgct cggttttcga atacagatag
    63901 atcgttcgtg acataaattt tcttttctgt cccccacgct actccgacga tttcctctgt
    63961 atgataattg tcgcccatca tttccacgta caacgccata tccgtagtaa acatttcctc
    64021 tttgaattca tgaacgactt caaacaaaat atcatccatt tttacttctt cttctacgat
    64081 attcaattta gaaaggaact gattgaaatc catttcttta taaaacggaa cgagtttatc
    64141 gagatttttc ccttcatact tcaatgagtc gatagagaca tccacaggcg ctgaagtatt
    64201 gatggtcgcc aattttttcg ataagaaagc ctgctctttg tcatttatca gattttcttt
    64261 cattttgctt tgcttcattt catcgatatg ttcataaatt ccttcgactg agccatattg
    64321 tttcaatagc ttgatagctg ttttttcacc gattttagtc acaccgggga tattgtcaga
    64381 ggcatctccg gctagtccct tcatgtcaat aatctgtttt ggcgtcaacc catcatattt
    64441 ttccgctaca tgttctggtg tatagctttc gatatcgctg acacctttta cagtgatatc
    64501 cacttttact tctttactag ctaattgagt caaatcccga tcacctgaaa gcacgacgac
    64561 atcaaattga tctttgtcta ctttttctgc caaagtaccg ataatatcat ctgcttcata
    64621 attgggcaat tcgtaatact gtacccctag tcctgtcaac aaatcacgta tatatggcat
    64681 ttgttctttg aattcgccag gtgttttgga tcttccacct ttgtactccg catacatttc
    64741 tgtccgaaaa gtcgtttttc ctgcatcgaa cgcaaccaga acatgagtcg gttgctcttt
    64801 ttgcataaca ttttcaaaca tcgtattgaa tgcatagatt gcatttgtat gaagaccgtt
    64861 tctatttttg aaacgttcaa gagaattgtg aagcgcaaag aatgcgcgaa aagccacact
    64921 gttcccatca acgagtaata atttattttt tgtcatcttc ttaactcctt actgtaaagt
    64981 tcttattcat tctaacaaag aatcctgcgg aatgcgaaaa gaaaaagcgg gaccatacca
    65041 aataattcgg tatagcccca actgatgaat ttttttcttt tttagttgtt ccgtccaaag
    65101 attctcagaa acgccaagaa caagttgata aagtccaaat acagcttcaa tgccatgaat
    65161 acagcaattc cactatgtgc tgttccgttt gtctggacat agatattacg gatgctttgg
    65221 ttatcataag ctgtaatccc tgcaaagatg acgactaaca gtagggagat gaacagctca
    65281 actacgctac ttctcaaaat gaagatgttc aagactagtg caatgatcac tccgattaaa
    65341 gctgcctgtc ctgctcttcc aaccccgcta agatctcttt ttgttgttac tccgacaaca
    65401 gacatcccca tgaacatcaa agtagctgtc aagaaagctt gcgttactgt tccaatatcg
    65461 tagtatgcaa gagtaaccgc taatgttatg ccattcaaaa gagagtaggc aataaatcca
    65521 ccgattgcta agctcggatt cttttgtgct tttacgccta gaaccattac taaaatcagt
    65581 tcaacgatcc acagacccac aaagcctagt ggaaaattat tgataaaagt tgctaattgc
    65641 aaaggaaata cccaaagagc caagtaagaa gtgactgcac taagggcaag tcccatacct
    65701 aaaaatccat aaacttttgc ataaaaacga ttgatacctg acattgatgt acttggatta
    65761 ttcattcaat tcaccttcac tttcgattgc tatttccaat tcaggaactt gtggcggttg
    65821 gaccataacg acagcatcca acacacgatc ttcgttcgta ttctccgctt ctacagaaat
    65881 cgtcaccaca tccttcatct tatctacttt tatgacctca aactgaaaag tcagtgtttc
    65941 ataatggaaa accggttcaa taaaattgac agaaaaattg acaacatgtg atcctggtcc
    66001 aggaagatgc tttgaaattg cacttgtgat gatccccatc agcatcactg atggaacgat
    66061 tggctgttga tattctgttt tttgtgcaaa gtcatgttgg atatacaaag gatttgcatc
    66121 attcgtcaat cccaaataca gcaaaagctg gttatcttca atagattctg ttaaggataa
    66181 cgagtcgcct tcctcgattt catttattgt ttttcctagt tttctcggct tacctatgtt
    66241 caagatagaa accctccagt ttatttttaa tcatacatta ttgtaccaaa agtagcgtaa
    66301 aaggcaagtt ctgctccctt gatttaacag attcctatag tttacagagg tcgtgaaaaa
    66361 gctgtcctgc atcaaataat aagaacagcc aagaaaaaac agcttctcat gtttttgatt
    66421 tgattgggct tattaccgca gatgcaagct tttgaacacc gtttatcata agttgcaaaa
    66481 aagggggctt ggcaagattt ttgccactcc ccctctttct atttttataa ggacactgca
    66541 gtaattgtat tacagtacat ttttcgtcgt gctgcttaaa agtttttcat acgcttgttc
    66601 aaatttttga acatctccag cacccatgaa gattactact gcatcatgat aatctaacaa
    66661 tggagataca ttattttctt tgatgacttc tccacctttt ttgattttcg ctccaaggtc
    66721 ttcaatctta acgtttcctt gttcttcccg agccgaacca aaaatatcgc ataagtaaac
    66781 tttatcagct aaatcaagtg cttctgcaaa ttcatccatc aatgcaatcg tacgcgtaaa
    66841 cgtatggggt tggaaaactg caattatttc tttatctgga tatttttggc gtgcgccatc
    66901 aatcgttgct ttgatctctg cagggtgatg cgcataatca tcgactacgg tcatgtctgc
    66961 tacgatcttt tcactgaatc gacgttttac tcctgggaaa gtcagcattt cttctgcaac
    67021 ttctttcaga tccagttttt cgaaataagc tactgcaata acacctaaag catttaagat
    67081 attgtgttta ccgaatgctg gtacagtgaa gtgcccaaca aattcatccc catgatagac
    67141 atcaaaagca gaaccagaag ttgtgcgttc gatgtttcgt gcttggatat catcgttttc
    67201 tgtgacacca taataataaa tcggcacatt tgcttttaat ttgcgtaaat aagcatcgtc
    67261 accatacgca aaaatagctt ttttcacttg tccagccatt gtttggaaag ctgtaaatac
    67321 atcgtcgata cttgtataat aatccggatg atcaaaatcg atattggtca tgattgcata
    67381 gtctggtgaa taggcaagga aatgacggcg atattcacag gcctcaaatg aaaagaattc
    67441 cgcttgcgga tcaccatgtc ctgttccatc tccaattaga taacttgttg gacggacacc
    67501 actcaataca tgagagagca gtccagtcgt acttgttttt ccgtgagagc ctgttacagc
    67561 gatactcgta taattttgga taaaatgacc aataaagtcg tgatagcgaa tcacttccaa
    67621 acctaattct tttgctcgct ggatttcttc atgtgaatca ggaaatgcat ttcctgcaat
    67681 gatcgtcatc cctggtttta cattatctgc gttaaatggc agaatcgtga tatttgcttt
    67741 ttctaaatct ctttgtgtaa agaaatattt ttcaatgtct gatccttgga catttagacc
    67801 ttgttcatgt aaaacaagag ccaaggagct cattcctgaa cctttgatac caacaaaatg
    67861 atacaattta ttttgatttt ccatttgaat cctcttctct tatctagcgt ccattctttt
    67921 agctattaca ttcaacacgc tcctcattat cttataaacg attgaaaatt tcaaccaaat
    67981 ttatttggaa aggaggattc gcttgctaaa atggtcaagt acgagaaaaa tccgttttta
    68041 ttgactcttt aattctggtg taagaagacc aaacttcctc tgatatatca atgtgaggaa
    68101 taaaatcttt tcctttcgga ccatagccgt tctcatcgtc atggagacgt tccatttctc
    68161 ctaatactag cgcatggaaa tattccttag gccattgatg attcagttct tttgctgtaa
    68221 agatgatctc ttcagaaaag tgaaggattt ccggcacaaa tggcacagca ttcgcgaaaa
    68281 tagtttgttc attttgccat actttctcaa aagttgctcg agtcctgcgt tgcagtgtcg
    68341 gatcattcat caataagatt ttttctggta cagctcctaa ggaatgaaga atctccagtg
    68401 aaaaagtggc gttctctcca gaatttgtag acttcgattc tatcagaaaa gccttatcgg
    68461 gcaaatcata gacttctttt agatactgac gacagatttc actttcactc atgccatctt
    68521 caaaatgaaa tccttgcttt tcaaaattct cataaaggat tctagtcgca tgccccaccc
    68581 ctccgaccaa aaacaattga tctacttggc catttaaata catttgtgct gctttatcag
    68641 ctaagatagg aagacagttt ccagctaaaa taagtgtagg tgccgtcagt tcctcaaaat
    68701 ttccctcttc aggtgcggct aaaaaattta atagctgatt ccagtctttt agattcctct
    68761 gctcactttt ttccaaaggc cttctatcct ttcatctgat tttttgtgct tcattaaagt
    68821 cttctctttt tgtctcaatc catttgattt ctccatgaca tcttccacaa cgatatttgc
    68881 gtacatcgat tcttctcttg cggcagatcg tggcagaaca atcttggcat cgataatact
    68941 ccatctttat ctgtttcttc gtcaaggctg gtgcatagcg caaccctcct gtttttttca
    69001 aaagatactt gaaatccata tctttatgct gataccctct tccagctaga tgaagatgat
    69061 aatggcaaag ttcatgtttg atgattcctg caatcgtctc ttcgtctgac tcttcaaata
    69121 gcttcgcatt aaaatctaaa tgatgatcgt ttaaatgata gcgcccgcca gttgtacgta
    69181 agcgtggatt gaacattgct tggtgcttga aaggaagctg gaagcttttt aatgatatct
    69241 cttctactaa ctgctgcagt tcttcttgtg tcaatttttg ttactcctca ttgttactct
    69301 tcataagggg aaagcatcgt caaactgatt ctgccttttt tcgtatcgac ttgttctatc
    69361 caaactgtta cgatatctcc tactgacacg acatctgtag gatgcttgac gaattttttg
    69421 ctgagtttcg atatatggac aagtccgtct tgcttcacac cgatatcaac aaatgcgccg
    69481 aagtcaatga cattacggac cgttccagtc aattccatcc ctggtttcaa gtcttccata
    69541 ctcaatacat ctgtacgtaa taagggcgct ggcatctcat cacgcatatc tcgtccaggt
    69601 tgtgtcagcc cagctaaaat atcggctaag gtttcttctc cgactgatag gctttcagcc
    69661 agtttctcta cggataatcg tgtcaatttt tctactgctt cttctgtacc aagctctttt
    69721 tctgaaagtt ggactgaagt taatatttct tttgcaatag aataactttc gggatggata
    69781 cctgtgttgt ccaaaatgtt tttcccacca gggactcgca agaatccgat tgcttgttca
    69841 tatgcttttg gtcctaagcg tggcactttt ttcaattgag ttcgtgcggt gaattctccg
    69901 ttttcttcac gataaatgac aatgttttgg gcagttgttt tattcaatcc tgatatatgc
    69961 tgcaagagct gcgggcttgc tgtattcaca tccacaccta cttggttaac cgctgtttcc
    70021 acaacaaaat ccaattgttc agccaaacgt ttttgagaaa cgtcatgttg gtactggcct
    70081 actccgacag ctttaggatc gattttgact aattcagcta aaggatcttg caggcgacgg
    70141 gcaatagaaa cagcacttct ttcttcaact tgtagatgcg gaaattcttt tcgtgcaatt
    70201 tcgctagcgg agtaaacaga agcgcctgct tcgttgacga tagcgtaata ggttttatgg
    70261 tcggcggatt tcaactgctc agccacaaaa agttcagatt cccgactggc tgtaccattt
    70321 ccgatagcta ccatatctac ttgatattta ttaattaatt ggataaaagc tggtccagca
    70381 gcttctcttt ttgcttgcgc tgcaggttta tgaggataaa taacttcgat tgctaaaact
    70441 ttccctgtcg catctacgac tgctagttta catccagtac gataagccgg atcaaatccc
    70501 aggacaactt taccttttag tggcggttgc aacaaaagat tacggaggtt ttcgccgaaa
    70561 atagcgattg cttgctcatc tgccttttca gtcaattcat tgcgcagttc tcgctcgatt
    70621 gctggctgaa taaagcgttt ataactatcc tgataggctt ctctgacgaa tgaagaagaa
    70681 ggagaggcag gatttttgac tatttggcga tccaagtaag ctaaaattgc tgcttcatct
    70741 acttgaaaga atactttcag aatatcttct ttttctccac gattagtagc taatattcga
    70801 tgagaaacca ttttatggac gggttctgca aagtcataat acatttcata tacgcctttt
    70861 tcatctgctt gctcatcctt gacattgctg acatacatac ctttgttata cgtataagac
    70921 cgaatccaag tccgaaattt tgcattatcg ctgacttgtt cagcaataat ctcatgagca
    70981 ccgtgcaacg cttcttcggc agaagagact tctttttctt tgtcaatata tttttctgct
    71041 tcagattgca cctctccatc tgtaagctgc atcagccact tcgcgagtgg ttcaagtcct
    71101 ttttctttag caatcgttgc ttttgtccgt cgtttttgtt tgtatggacg atacaaatct
    71161 tccacttgtt gcattttcac ggcttgggtg atttctgctt ctaactcggg agtcagtttc
    71221 ccttgttcat cgattagccg aatcacttca gttttacgtt tttctaagtt ttcaagatag
    71281 gcataccgct cttcgatttc acgaatctgg acttcatcaa gacttccagt catttctttt
    71341 cggtaacgcg cgataaaagg aacagtgttt ccttcattta acaaattaag tacagtagtc
    71401 aactgcttag gacgatagtc tgaaagttct ttttgtacaa gctgaatgat cgtctggttc
    71461 aaattttccg tcattaaaat gcctcttttc tgctaaaaat tgcttcttta ttctatcata
    71521 ctttttatcc tgggttaaac tactgaaaga aacaatattc tctataaaaa taaaaagagc
    71581 cgcaacaaag tcacagctcc ttcattcttt ccattagtca gattccatgc caaggtcctt
    71641 cgttgttctg atattcaata tcttgaagaa taccttcctt gtcaaaaaca accccatgca
    71701 atgaccctcc gaatacagcc ccaccgtcca ttccgatttt atgatcctga atccagaggt
    71761 ctgttgtctg catatctcca tggagcattg gtgtaatcgt atgtccaaat acaattgtct
    71821 tacctgtatt gtttttccct tcatgaaatg gttcccttat ccaaataaag tctcttagac
    71881 ttgtcttacg ccagtctttc tttgtcaaat ccacaccggc atggacaaaa agataatttt
    71941 cccattcata atacaagggg cgctggacta aaaatttaat cagttctgaa tatctcgatt
    72001 ggatcatcat cgagatttca gttggggagt attcctccga tgcccctggg tgaatcaggc
    72061 tttcaaacgt ttcttttcca ccatttctca tataaggcgc ataccagtcc tccggtgatt
    72121 gcagaaattg caaaaaatat tcttcatggt ttccccggag gtaaatggct cctgtttctt
    72181 cgactaattg ctttcctaat aaaaaacatt cttttgtacg aggacctcga tcattgagat
    72241 cccctaataa aacaagctga tggatctttg gatcataata gtgaataagt ttttcaaaaa
    72301 gctcatgttt gccatggaca tccccaatag cataaatcaa tgatttcatg tggatcacca
    72361 tcctcaacgc tagtatagcg catattggaa atggtcgaca atcaaaacta ttgttttcta
    72421 tttaattaaa gctgtaaacc gcagttctgc ttcttctgga gagattccat ggtcttgaac
    72481 atagcgattg cgcggatgtt tcgcacactc tatgctacat gctcctaaat gtttttcttc
    72541 attttcaatg gaagcaagaa tctgacgatt gcactcagga ttgctacaat tgatatatcg
    72601 ttcacatggt gttccgtcaa accagtcgcg accgacgatt tgtttatcta cttggttgat
    72661 atcgacagcg atccgttcat caaacacata catcttgccg tcccataatt ctccttggac
    72721 ttcaggatcc ttaccataag tagcaatacc gccatgcagc tgtccgacat ctttgaatcc
    72781 ttcacggaca agccaaccag aaaacttctc gcaacgaatg ccaccagtac agtaggtcac
    72841 tacccgtttt tccataaatt cttctttgtg ctcgcggatc cagtctggaa gctctcgaaa
    72901 actgcgtata tctgggcgta cagcccctcg aaaatgtccc aagtcatatt cataatcatt
    72961 ccgtgcatca atcaccactg tctgttcatc taaaatagct tctttaaatt cttgcggtga
    73021 aagataggca cctgtcactt ggtttggatc aatgtcctct tctagcttta aacttacaag
    73081 ctctggacgg tatcttacaa acatcttctt aaaggcatgt ccttcgcttg gatcgatctt
    73141 gaacatcgta tcagcaaatc gaggatcagc tttcattgct ttcatatagg cagtcgtgtt
    73201 ttcaacggtt ccagacacag taccatttat tccttcttca gctactagaa tacgaccttt
    73261 aagatccaaa gatttgcaaa aggctaaatg atttttggca aattcctctg gttcttcgat
    73321 ttttgtataa ttgtaataaa gcagtacttg ataatccatg tatttcttcc ttccttcttt
    73381 tcgttcctaa acagtataaa gaaggcgttc gcatttgacg atttatttgc ttgtgtataa
    73441 ttacgcatgg aaagtttttt gtttacataa tattattatt tgaattaaaa agacttcgct
    73501 ttcctgtttc gcacagaaaa a
//
LOCUS       DARPZF010000009        67763 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.009, whole genome shotgun sequence.
ACCESSION   DARPZF010000009 DARPZF010000000
VERSION     DARPZF010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 67763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.009"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(99..1229)
                     /locus_tag="SLE65_000856"
     CDS             complement(99..1229)
                     /locus_tag="SLE65_000856"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEI8448168.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="SLE65_000857"
     CDS             complement(1878..3080)
                     /locus_tag="SLE65_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEI8448169.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="SLE65_000858"
     CDS             complement(3140..3343)
                     /locus_tag="SLE65_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HEI8448170.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEQLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="SLE65_000859"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="SLE65_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="SLE65_000860"
     CDS             4880..5692
                     /locus_tag="SLE65_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8448171.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6716..6913)
                     /locus_tag="SLE65_000861"
     CDS             complement(6716..6913)
                     /locus_tag="SLE65_000861"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HEI8448172.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="SLE65_000862"
     CDS             complement(7059..7937)
                     /locus_tag="SLE65_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEI8448173.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="SLE65_000863"
     CDS             complement(7976..9094)
                     /locus_tag="SLE65_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HEI8448174.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="SLE65_000864"
     CDS             complement(9091..11190)
                     /locus_tag="SLE65_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HEI8448175.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="SLE65_000865"
     CDS             complement(11241..12062)
                     /locus_tag="SLE65_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEI8448176.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="SLE65_000866"
     CDS             complement(12059..12868)
                     /locus_tag="SLE65_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8448177.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="SLE65_000867"
     CDS             complement(12889..13383)
                     /locus_tag="SLE65_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8448178.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13883)
                     /locus_tag="SLE65_000868"
     CDS             complement(13395..13883)
                     /locus_tag="SLE65_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEI8448179.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13960..16656)
                     /locus_tag="SLE65_000869"
     CDS             complement(13960..16656)
                     /locus_tag="SLE65_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEI8448180.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="SLE65_000870"
     CDS             complement(17084..18157)
                     /locus_tag="SLE65_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEI8448181.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="SLE65_000871"
     CDS             complement(18154..18981)
                     /locus_tag="SLE65_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8448182.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="SLE65_000872"
     CDS             complement(18982..19788)
                     /locus_tag="SLE65_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8448183.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="SLE65_000873"
     CDS             complement(19800..20885)
                     /locus_tag="SLE65_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8448184.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="SLE65_000874"
     CDS             complement(20902..21444)
                     /locus_tag="SLE65_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8448185.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="SLE65_000875"
     CDS             21702..22691
                     /locus_tag="SLE65_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HEI8448186.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="SLE65_000876"
     CDS             22688..23425
                     /locus_tag="SLE65_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEI8448187.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="SLE65_000877"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="SLE65_000877"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEI8448188.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="SLE65_000878"
     CDS             23989..24621
                     /locus_tag="SLE65_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEI8448189.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="SLE65_000879"
     CDS             24706..25353
                     /locus_tag="SLE65_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8448190.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="SLE65_000880"
                     /pseudo
     CDS             25358..26341
                     /locus_tag="SLE65_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
     gene            complement(26744..28258)
                     /locus_tag="SLE65_000881"
     CDS             complement(26744..28258)
                     /locus_tag="SLE65_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HEI8448191.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28396..29202
                     /locus_tag="SLE65_000882"
     CDS             28396..29202
                     /locus_tag="SLE65_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448192.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29377..29946)
                     /locus_tag="SLE65_000883"
     CDS             complement(29377..29946)
                     /locus_tag="SLE65_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8448193.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30029..32089)
                     /locus_tag="SLE65_000884"
     CDS             complement(30029..32089)
                     /locus_tag="SLE65_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEI8448194.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32366..33844)
                     /locus_tag="SLE65_000885"
     CDS             complement(32366..33844)
                     /locus_tag="SLE65_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8448195.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(34142..35077)
                     /gene="murB"
                     /locus_tag="SLE65_000886"
     CDS             complement(34142..35077)
                     /gene="murB"
                     /locus_tag="SLE65_000886"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEI8448196.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(35150..36070)
                     /locus_tag="SLE65_000887"
     CDS             complement(35150..36070)
                     /locus_tag="SLE65_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEI8448197.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            36183..36935
                     /gene="xth"
                     /locus_tag="SLE65_000888"
     CDS             36183..36935
                     /gene="xth"
                     /locus_tag="SLE65_000888"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEI8448198.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            37799..38332
                     /locus_tag="SLE65_000889"
     CDS             37799..38332
                     /locus_tag="SLE65_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HEI8448199.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(38822..39346)
                     /locus_tag="SLE65_000890"
     CDS             complement(38822..39346)
                     /locus_tag="SLE65_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8448200.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(39339..39812)
                     /gene="tsaE"
                     /locus_tag="SLE65_000891"
     CDS             complement(39339..39812)
                     /gene="tsaE"
                     /locus_tag="SLE65_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEI8448201.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(39935..40915)
                     /gene="pta"
                     /locus_tag="SLE65_000892"
     CDS             complement(39935..40915)
                     /gene="pta"
                     /locus_tag="SLE65_000892"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEI8448202.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(41068..41748)
                     /locus_tag="SLE65_000893"
     CDS             complement(41068..41748)
                     /locus_tag="SLE65_000893"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEI8448203.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            41874..42743
                     /locus_tag="SLE65_000894"
     CDS             41874..42743
                     /locus_tag="SLE65_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEI8448204.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            42769..43284
                     /locus_tag="SLE65_000895"
     CDS             42769..43284
                     /locus_tag="SLE65_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448205.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(43331..43924)
                     /locus_tag="SLE65_000896"
     CDS             complement(43331..43924)
                     /locus_tag="SLE65_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8448206.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(43949..44128)
                     /locus_tag="SLE65_000897"
     CDS             complement(43949..44128)
                     /locus_tag="SLE65_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448207.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(44205..44714)
                     /locus_tag="SLE65_000898"
     CDS             complement(44205..44714)
                     /locus_tag="SLE65_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448208.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(44810..45190)
                     /locus_tag="SLE65_000899"
     CDS             complement(44810..45190)
                     /locus_tag="SLE65_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEI8448209.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            45520..46269
                     /locus_tag="SLE65_000900"
     CDS             45520..46269
                     /locus_tag="SLE65_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEI8448210.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(46453..47730)
                     /locus_tag="SLE65_000901"
     CDS             complement(46453..47730)
                     /locus_tag="SLE65_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448211.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCHYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(47809..48453)
                     /gene="pcp"
                     /locus_tag="SLE65_000902"
     CDS             complement(47809..48453)
                     /gene="pcp"
                     /locus_tag="SLE65_000902"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEI8448212.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(48652..49596)
                     /locus_tag="SLE65_000903"
     CDS             complement(48652..49596)
                     /locus_tag="SLE65_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEI8448213.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(49598..50284)
                     /locus_tag="SLE65_000904"
     CDS             complement(49598..50284)
                     /locus_tag="SLE65_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEI8448214.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            50758..51078
                     /locus_tag="SLE65_000905"
     CDS             50758..51078
                     /locus_tag="SLE65_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HEI8448215.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            51232..52137
                     /locus_tag="SLE65_000906"
     CDS             51232..52137
                     /locus_tag="SLE65_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8448216.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            52134..52907
                     /locus_tag="SLE65_000907"
     CDS             52134..52907
                     /locus_tag="SLE65_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEI8448217.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(53088..54512)
                     /locus_tag="SLE65_000908"
     CDS             complement(53088..54512)
                     /locus_tag="SLE65_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8448218.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            54723..55169
                     /gene="nrdI"
                     /locus_tag="SLE65_000909"
     CDS             54723..55169
                     /gene="nrdI"
                     /locus_tag="SLE65_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEI8448219.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(55234..57216)
                     /locus_tag="SLE65_000910"
     CDS             complement(55234..57216)
                     /locus_tag="SLE65_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEI8448220.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(57230..58126)
                     /gene="murQ"
                     /locus_tag="SLE65_000911"
     CDS             complement(57230..58126)
                     /gene="murQ"
                     /locus_tag="SLE65_000911"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HEI8448221.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(58129..59190)
                     /locus_tag="SLE65_000912"
     CDS             complement(58129..59190)
                     /locus_tag="SLE65_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEI8448222.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(59401..59967)
                     /locus_tag="SLE65_000913"
     CDS             complement(59401..59967)
                     /locus_tag="SLE65_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEI8448223.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(59995..61497)
                     /gene="eat(A)"
                     /locus_tag="SLE65_000914"
     CDS             complement(59995..61497)
                     /gene="eat(A)"
                     /locus_tag="SLE65_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HEI8448224.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(61755..62876)
                     /locus_tag="SLE65_000915"
     CDS             complement(61755..62876)
                     /locus_tag="SLE65_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEI8448225.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            63002..63943
                     /locus_tag="SLE65_000916"
     CDS             63002..63943
                     /locus_tag="SLE65_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEI8448226.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(64093..64989)
                     /locus_tag="SLE65_000917"
     CDS             complement(64093..64989)
                     /locus_tag="SLE65_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HEI8448227.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            65258..66598
                     /locus_tag="SLE65_000918"
     CDS             65258..66598
                     /locus_tag="SLE65_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8448228.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            66816..67259
                     /locus_tag="SLE65_000919"
     CDS             66816..67259
                     /locus_tag="SLE65_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HEI8448229.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
BASE COUNT        19977 a        13995 c        11788 g        22003 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagctgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatataa gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gtcaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttgccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactag cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatcaaaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    26401 aaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggaattt
    26461 cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg
    26521 tcccacgctc tttttccgaa taaacggtgt tcaaaagctt gcatctgcgg taataagtcc
    26581 aaccaagtta aaaacataag aagctgtttt tacttggctg ttcttattac ttgatgcagg
    26641 gcagcttttt cacaacctct tcactaaaca gtgttcaatc agctgaccct cggtattagc
    26701 tcaaaacgct gatttcacaa cctcttttta tttacgttct atttcattca ttttccgaag
    26761 caaatcgagc tgcttgtatg cccgcttgtc gcccaaaaat aatgatctcc gcaactgaat
    26821 ttccaccgat ccggttgttt ccatgtaagc cacctgtgac ttcaccagca gcatataacc
    26881 ccctaattgg ctggttttct ttatctaata cttcagtgtt cgtattgatt ttcacaccgc
    26941 ccatcgtgta atggattcct ggtgcgattt tgatcgcata ataattcgga gacgataagt
    27001 catgttccat ggctgtggca cggttgaatt gagcatcttt tttctccgca acatccgtat
    27061 tccatccatc aactgttttt gctagtgttt cttttggtaa atcgattttt tctgctaatt
    27121 cttccattgt ctttccagtt gtgacatatc ctttttggtc ataaaattca atagctgtgg
    27181 cacgatcacg cacgccttgg tcaaaaatca aataagctga tttttcaggc aatgctgtaa
    27241 ttgctgcaga tactttatcc cttgtatcca tttcattgac aaatcttttc ccctcttgat
    27301 cgaccaagat tgctccttct ccgcgaacaa cctcaccaat caagaccccc tcatcctgct
    27361 gcacagttgg atgaatttgt attttatcca tatcaacggt ttgtccacct aatttttcaa
    27421 tcatggtgat accatctcca gttgatcctt cttgatttgt cgtaatataa tcagctaaat
    27481 cgggacgata tttttcaata aattctttgc tggcaccaaa accgcctgtg gtaactacga
    27541 ttgcttttcc ggtgacctct tttggttctt ctccttgaac atgtacagtc acttcattga
    27601 ccgtttcccc atttttctta atgtctgtca catctgcgtt gacaaaaata gggatttccc
    27661 gctcatggac gttattcaat aacccctcca ctaagtatcc accaatagcc gagccatcag
    27721 acggacgatg tgtcctcttt tcactcatcc ctccagtgat cgttaagttg tccagtttga
    27781 taccgttttg atctagccaa tcgaccgcat cagcagagtg atcgacaaag tatcgaagca
    27841 tttctttatc attcgttcct ccaccacctt ttagcgtttc ttcatagaag gcatcattcg
    27901 agtctttgat tccttcttct ttttgaaatt ttgtttctga agcattcata ccgcttgatg
    27961 atttagatgt gtttcctccg gcaacaggca tcttttccaa aattactgga ttcaacccag
    28021 catcttttgc ttcgatagct gctgccatcc ctgcaccacc agctccaata atcacgacat
    28081 cataagattc tttcatttct tttggatctg tatatacttg ttcagaagcg cctgatgata
    28141 cttcggcaga ttccttcgta ctagaacttg tctgcgctgt atttttctga tctgcgccgc
    28201 atgcgctcat agcaagaagt gcaacggctg ttaataaacc agcaactaat tttttcattt
    28261 gtatccccct tttctcctta tactatatta agtgattttt ttcacaatat caactctgtt
    28321 tttctttaag tcatatagct ttggtaaaca cacgcttctt agtataatta aggatataca
    28381 tgaaggagtt attttatgaa tcatttgaaa acctttttta cgaacagtac aaaaactgca
    28441 ggtagaatca caaacggaat ctatatttta ttacgtatca tcgtcgttat tatgctagtg
    28501 gatcaggtct ggaaccaaca ctggggaaat acaatgcttt tattactgac attaatttta
    28561 tttgaaatcc cttattttct ggaaaagata ttaaagatac agattccaaa tatgctagaa
    28621 atcattttgt tatcttttat ttttagttca acagttttag gagagttaag tgatttttat
    28681 ggctattttt caatgtggga tacttttcta catgcattca gcggattttt agctgggggt
    28741 gtcggctttt cccttgttta tttgctcaat aaaaatacaa aaaccatgaa cttgactcct
    28801 ttattactag cagttgtttc cttctgtttt tcgatgacag ttggtgttat gtgggagttt
    28861 gtggaatttt cagcagataa attactgcaa ttcgatatgc aaaaagatac gatcatccag
    28921 caaatcaata gtgtggagtt aagtaaagac ggaaacactg tctatcatgt tccagatatc
    28981 actcggacaa tcattgaaag tcaaaatgca gatggtaaaa cagataaaac aatcatccaa
    29041 aatggttact tagacgtggg aatcatggat actatgaagg atttatttgt taattttatt
    29101 ggagcagttg ttttcagtgt atttggttac ctctatagtc gaaacgatta ccaaaaattt
    29161 acgttcatca agaattttat tcctaaaaaa atcaaacgat aaaacatgct aaaaaacaag
    29221 agaaggggca gtgacaatac ttttgtcact gccccttctt ttttgaatgt atggcatgcc
    29281 attagttatc cgatagtatt aactcaaaaa agtaagatat gaggaatgac tatttcgttt
    29341 tttatcccaa tactgaggac ttatttcacc atttcgttat ttatctaatt tacttaaaac
    29401 ctgcataact ttttcataat ctggattagg tgtgccgtct agattttcag caataaaagt
    29461 aaaacccatt tttttataaa gagcaatcgc ctgatggctc catgtctgtg tgtgaagata
    29521 gattggtccg tccgtatgga gggtaggaaa ttcttgcaag actctggcag tcaatgcttt
    29581 tgcgagccct tttccttggt aatctggttt cactgctaac caatgaaaaa ccggatacac
    29641 ttgctctctt gatttttttc gccaagcggt acaggttgct actttttctc ctttttttgt
    29701 ctctacaaaa aacatccttc tttcaagttc ttcaggataa ggagcaaagt tttgttgaaa
    29761 atactcaagt gcttcatctg tcgtttgaaa ttccccaacg gaagtctcaa tctccgccca
    29821 agcagattca tcttcttttt gataaaatcg aaattcaaaa ccttccgcta aaggcgtgat
    29881 tggaacattt tgttgaagtg gtcttgtcat ccagatttct gcgtaaggta acgttttatc
    29941 taacattttt ctatccctcc tcgtctccat tatgccaaat aacatatgac tcagctactt
    30001 atttgactat aacagataga gatataaatc agaaccagtc atctgcgtca aattcatttc
    30061 gattagcgta tacccatgtt cctgccatac ctcgcatgaa atctcctaaa gcagaagaag
    30121 gaatacctcc accaggtgcg ggtgttcccg gactaggaag tggtacttgc ggctgcagat
    30181 gctcatcggt ggaatcaata gttgacaagc gttttttctt cgtttccttc tggtcatctg
    30241 attccttctg atcttccgac tgtttagcaa caaattcttt ttctgattgt tgttttattt
    30301 taggctctaa aatttcattt tccaatccag aaacttgtgg ggccaaatga gcttcttgcc
    30361 ttatcgtttt attagattct gagatttttc tagatattct tgctaactct aggcttcttg
    30421 tttgttttac tttccctgtt ggagaaactg catgagccat ttgttgtttt ttttctgaca
    30481 agctttcttc ttgtcttttt tgttcttttt gatctatctg tttgtttaat ggtaaaacat
    30541 gtaatagtga ctgagcatgg agttcttgga gtgaatacgg gtcatgataa ctatacataa
    30601 tcgtaaaatc acctgtttgt ttggtcaaat aaccatcctc caatggtact tcattgattg
    30661 taaccgatac atcctttaac ggtacgggtt tacctaagga atttgttgct gattggatca
    30721 actcttcttt gtttattttt tcgtttggat gaacaataag atcatgacct tctaatgaac
    30781 gattgtctgg tatataaaca taagtaaagg taatttcccc tcctgattgc ttcctattat
    30841 tcatcagttc tgagtgaagt acttcaagga tctccgacca gtgacttttt ctgtctaatc
    30901 cgtttgcttg catccaatca gaaatagaag tgactttccc attttgttca taagtcgata
    30961 aatctatatt tggcactcga tcagaaaatt cagcaggtag gcgcaaatca ggaatacgat
    31021 ttacactact catatgtgtt tctgcttgaa gttctttatt tgtttgacta tctataaaat
    31081 gagtgatgac agtcgatgaa gcagcagatg cttctacata aactacagct gttgtttctg
    31141 ccacatttga tgttttcgag tctatataag ttaatacaac gggatattct cccggagttg
    31201 tagtatctac tgtcccgttc attttgattt cttctttatt tcctgaagtt ccatcgcttt
    31261 ttgttacata ttcaacaaga tctttagggg cgtaactctc tcctgttctt aagtgaagat
    31321 cttttccttt gatagctgtt tgatcagcac gaacatggat cacagcagat gcagtcattg
    31381 tttttaaagc aattggatca aaataggaca aggaaatagt agatgttcct gtattagtcg
    31441 tatccacgat attcccattg tttgaaatta ctttggacat atctccttgt gttccatctg
    31501 cgttcttcag cctttctacc agatcagata tcgaaacttt tgtccctgcc agaacatcga
    31561 ttttctttct ttcaaactgt gaataatctt tttcatatac ataagaaact tgtgcgcttc
    31621 caccgtcctt tatatctgtc aaagcatgat tcaaaatatc agtgatctgt tttaactgat
    31681 caccttttgt aggatcagtc atatcggaaa agatagaaag cggcacactg cttccggttt
    31741 ccgatgtcca taatgttttg ttaggaatta accagtagtg gtttatcgtt ggaggataac
    31801 tgactttatt ataggaagtc aatgcaggaa gtagctgttt tccatttgca tcagtgaaag
    31861 tatgagtaat agtgataggg gaatcagtgg tctcagaaac agaggtacgt acgaccttga
    31921 tggtttgtgt cgttgcctga acgggtacat gcatatagac acctacagat aaactgatca
    31981 gcatcgtgcg catcataaac ttaacgtagt gtttttcaga acacgaccgt tccttatcta
    32041 aacgacaagc gtgtttattt agttgttttg aacgtctttt tgaacacatt tattcttagt
    32101 cctccctact cttgtctaaa catgaagtag taattttcat aagatgattt cattatataa
    32161 ataaaatcaa aagaagatgg actattagga gagtattttt tttgattttt tattgtttca
    32221 agaaaatcgg aataataact tatgtacttt ttaattttgt taagtaatat atctagttat
    32281 atctagttat atctagttac cttttctttg aaaaaaacat aaatcagcta ataaatatgt
    32341 gagacaaagc tgccatccat aaatactagc tgattttttc agttaaatgt ctattttttt
    32401 ctctgatgat ggtatttcca aaatattccc agtcatctgg agtcggtgga tttttccaaa
    32461 ttatctgttc tttattaaat ttttcaagta aacaatcaga taaataaata ttcgtacgag
    32521 aagtgattcg actctcaatc acaatattgt aatttttaaa tcctttcact tgagaaataa
    32581 tgtaatcggt ataagcagat ccttgcgaaa aatcaataca gacatgaatc ggtgcttcaa
    32641 aatatgatac cggacaaata ccgaccaata aaaagagata atcataaaat aagcgaatca
    32701 tgaaacgttc atcttttccc aagaaatagc gtttattctc ttgtatgacc ttttggattg
    32761 ctgtactgaa tattggatac gtctcgaaga aaaactgtag ctgcttttta gacgtaaagc
    32821 tagtcatctc aaagtcgaat atccaatttt ttcgattgac atgcatcata cccatacgaa
    32881 gttcttttcg tatatatagt ctttcttctt cagagatttc aatcgaaaat ggtaattgat
    32941 caatcaattc cactgacatt ttttgactaa tcatgtggat atcatgaaaa tgagcttccg
    33001 caagtccaaa tgcgccatct aattcaaatt cttcttccgt gatcaaaaac aacatgatat
    33061 aagaaatctc atcaatgatc tgctctttag ggatatgaag aaaagaaata tgtgataaat
    33121 ccttgatgat cttcattcct tctgagctct taaagtattc atctgaaaag aaacgttttc
    33181 cgattggttg attcccatag gccctcaaca aactaatagt ggttagcaaa ttgaatttga
    33241 ttcgttttgt tgcagacagt tttaaattga acagatattc aaaatattgc acgatactct
    33301 ttgcttcatt catgacgctt tctctaaatg gcatagaaaa accattaaag accccgaaat
    33361 ataccccaaa taatacgttc cgtatgttta tttcttcccc aactaatatg tttttcttta
    33421 actttatttg atgctgttca agaaaagaga ctaattctct tctttttaca taggctcttg
    33481 atatgcttaa aaaatgattc tctgcaaatt tttcgatcgt tacttttgaa tccacgatct
    33541 ccgttaacag tcgagcaatt tttgatcgtt gaaagtagat tcttcttaaa tttttgatat
    33601 ccgtcaaatt cagacgttcg acatggatct ctgcttcttc tgaaatttgg atctctggct
    33661 ttgttttgaa ttcagtaaat tctttattta attctatgat ataatttctt gttttaaatt
    33721 tagacaaacc taatgtttca tataacttag gcagcactac ataattcttt ttctcaaatt
    33781 ctaaatatct agctagcagc agtttttctc tatcttcctc ttctataagg taatccaact
    33841 tcatatccta cacctcaaaa aatgcctcat accaattact tgatatgcag atgaaagttc
    33901 atcttttcac ctatactgat tttatgatgg attatgcttg ttttttcatc agttattctc
    33961 attttttatc ttttttttga gaatattgca aaaaatggaa aaatttatga ggaaatattc
    34021 tatatttttt gttttattgt gttaaaatgt acaagatttg cgccatttgc gtaaacaacc
    34081 acaaaaaaga gcaggacggc caccgtcctg ctcttttact tattttaagt tccattactt
    34141 attaattggc taaacttctg cttgtttctg atattgcttg tttttctcca atgatccgca
    34201 cttctgtttc taaagacaca tcaaattttt ctttgattac ttcttggatg tgcgcaatca
    34261 attcaatata atctgtcgct gtcgcatgat cgatattgac gatgaatcca gcatgttttt
    34321 cagagacttg tgcaccgccc catttcaggc cttgcaatcc tgcttgttgg atcagctgac
    34381 ctgtatagtg tcctactggg cgcttaaaga cacttccgca tgaagggtat tctaatggct
    34441 gttttgattg acgcaattcg gtcaactcat ccattcttgc tttgattgct tcataatccc
    34501 ctgtttgcaa actgaatcga gcttccaata cgatagcacg taattcttgg actttactgt
    34561 gacgataaga aaataccatt tcgtcttttg tcaaagtttt caatgttcca tcttcaagca
    34621 aaagatccac ttcagcaaaa acatctttga tctctccgcc atacgcacct gcattcatat
    34681 aaaccgctcc accgacactt cccgggatgc cgcaagcaaa ttcaaatcca gtcaatgatt
    34741 ctgccaaagc tgcataagtc gtatcaatca gtgaggcacc tgcttccgca atgaccatcg
    34801 ttcctttgac atgaatctgt ttcatttcag tcagcatgat gactacaccg cgaatcccgc
    34861 catcttgaac gatcagattg cttgcatttc ctaataccat ccaaggtata tcatggattc
    34921 ggcaataatc gatgatttgc tttacttctt cttgtttttt cgggaatgca aggacatcag
    34981 ctggtccacc tgttttcgta aacgtatagt tcatcaatgg ttcatcaaac aatatagtaa
    35041 tcgtggctaa gctttcaact atttcttctt tattcactga ggattttcct ttcttttctc
    35101 aaacgtcctc attattctat cacgcttaat acaatcttgc cagtcttgtt caaagttgat
    35161 gacggtagtg atctttaagc acttcctcac ataattcatg acttcttaca acttcttttt
    35221 gtttaagcaa ttctgtttcc gatttaccta aacggatctg agaaaagaag gcctctacca
    35281 ttggctcaaa cccgcgtttg actagcgtgt ttgtccagtc gccaaattct ttcacttttt
    35341 ttccatcagc atcttgaatg acaagctggg tcagatcgtt tacttcataa gtaccatttt
    35401 tacttgttac ttgatatttt tctatattag cgccacttgc taaatccatc gttaaaatag
    35461 ccgtttgatt ttgtgtttct aattgtaaaa tggcatattc caaaaattcc tttgtttctc
    35521 ttatctggta ttttgttctc aaaatgggtt catctaataa atacacagct gtatcaataa
    35581 gatgtaaaaa caaatcataa aggacgaact ctgtcgtttc ttttgccgct attcgatttt
    35641 tttgcaggtg gatcaaccgc ttatctggga tacgtttcaa ttcttctacc ataggagcaa
    35701 agcgccggtt gaaaccgatc atcaaaatta tttggttctt atcagctaat tcttgcaatt
    35761 cacgaacttc atttagatgg acactcagtg gtttgtcaat ataaacatgg ataccatttt
    35821 ctagacattt tttggctaat tcataatgta cttttgttgc tgcgtggatc atacatgctt
    35881 cgattttttc ttctaaaagc tcatcgatcg tttcatatag atgttggaac ccgtactctt
    35941 tttgaattct ttcttttgtt tctttatttc ttgttgcaaa ataaaaatca agtgttcctt
    36001 gttttttcgc ataagttggt aaatatgctt tttctgcgat attccctaca ccgattacac
    36061 caatcttcat ctactttcct cctggatcat ttagttactt tcatcttaca ccatttttta
    36121 ctaaaatgag gtacaatagt atcgcaaagg taaggaaatt aattcgaagg agtgtgcttt
    36181 tattgaaatt tatctcttgg aacgtaaacg ggcttcgtgc catcgtaaat aaaaattttt
    36241 tagaagtttt tcatgagtta gacgccgatt ttttctgtct gcaggaaacg aaactccaag
    36301 caggacaaat tgatttagat cttccaggtt attatcaata ttggaattac gcggaacgaa
    36361 aaggctattc cggcacagcg atttttgcta aaaaaccagc attgaatgcc acttacggaa
    36421 tgggtatcga tatccatgat acagaaggcc gtctgattac tttggaatat tccgatttct
    36481 ttcttgtaac ctgttacacg ccaaattctc aaagcgaatt aaaacgttta gattaccgat
    36541 tagaatggga agaagccttt tataattatt tggaaaatct aaaaaaacaa aaaccagtca
    36601 tcgtgtgtgg ggatctaaat gtcgctcatc aaaagattga tttgaaaaac tggaaaacga
    36661 atcaaaaaaa tgctggattc actccagaag aaagagcggc tctttctcga ctgttggata
    36721 acgggtttat cgatacattc cgttattttt atccaaccca ggaaggtgtc tactcttggt
    36781 ggaactaccg attcaattca aggaaaaaca atgctggttg gcggatcgat tactttttga
    36841 cgagcaaaga tttagagcca ggactagctg atgcaaagat ccatacggac attatgggca
    36901 gtgatcattg tccagtagaa ttagatttga aataaagagg ttgtgaaaaa gtcgtttagt
    36961 ttcgagtatt aagaaaaatt ttgtgaaaat ggctttccac attttgcata aatttggcat
    37021 aataccgaga aactggcttt tgaacactgt ttatcgagag attgtgaaaa agctgtcctg
    37081 catcaagtaa taagaacagc caaacaaaaa tagttcctca tatttttcgt ttggttgggc
    37141 ttattaccgc agatacaagc ttttgaacac cgtttattaa gaggttgtga aaaagctgca
    37201 ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatattttt cgtttggttg
    37261 ggcttattac cgcagatgca agcttttgaa caccgtttat taagaggttg tgaaaaagct
    37321 gcactgcatc aagtaataag aacagccaaa caaaaatagt tcctcatatt tttcgtttgg
    37381 ttggacttat taccgcagat gcaagctttt gaacaccgtt tattgagaag ttgtgaaatc
    37441 agcgtcctga cctgagtatt agagaaacaa atggcaaaat agttcctcat attttgctat
    37501 tttttgagct aataccgagg gtcagctgat tgaacaccgt ttagtggaga agttgtgaaa
    37561 aagtcgccta ctttcgagtc gtaagaaatt tttttgaaaa tggttcctca caactttgca
    37621 taaatttgac ttaataccga gaagtcatga tccccatcta actccaaatc acaaggaatg
    37681 agttcaaaaa ctagcttttc tcaacaaata ttacataaaa aattctatgt tttttgttaa
    37741 atttatttgc ttttttcaaa agtatgttac agtaatttcc caaggaggtt ttacagaaat
    37801 gaattttgtt gccatggatt ttgaaactgc caatcatcag ccttatagtg cttgttctct
    37861 tgcgctagtc atggtaaaaa atagccagat cgttgatgaa ttctatacat tgatacagcc
    37921 tgagactcct tttttctggc gaaatgtcca aattcacgga atccatcaag aagacgtacg
    37981 caatgcgccg aaattcccag aagtctggca aactatccaa ccatattttc aaaaaaatcg
    38041 tttagtcgtt gcacataatg ctgcttttga tacaaaggtc ttagcgggat gcttagatta
    38101 ttatcatctt gaacagccta attatctttc tttatgtaca gtgaaaagta gccgtcgcct
    38161 gtttcctgaa tttccaaatc atcgattgaa cactgtgtgc gaaaatttga acatccaatt
    38221 agatcatcac catgatgcat tggaagatag tcgtgcatgt gcggaaatcc tgctttatca
    38281 agaaaaaaaa ttcgggacag atccattgaa aaaacttgtg actataaagt aaaagaatac
    38341 ttatgaaaca cacaaagagg tcgtgagcct gccgtttcac tccgagtcac aaggagcaat
    38401 ttcaaaaaat agcttctcat gtttattaaa tattgtgact ggtgaccgag gagctggcag
    38461 gagaacaccg tttattggag aggttgtgaa aaagctgttc tgcatcaagt aataagaaca
    38521 gccaaacaaa aatagcttct catatttttc atttggttgg acttattacc gcagatgcaa
    38581 gcttttggac accgtttacc aagaggttgt gaaatcagcg ttttgacctg agtattagag
    38641 aaacaaacgg caaaatagtt cctcatattt tgccgttttt tgagctaata ccgaaggtca
    38701 gctgattgaa caccgtttat tcaaaaaaaa tggactgcga cacgactttt gtcacagtcc
    38761 cttcgtgtgt ttttctgcct tctcaaaagg atgacagttt ctcactcttt tcctatttct
    38821 tctattcaat caaataactc attttatata catctaaaaa ttcacctaga tctgttcttg
    38881 cccctctagg catgaccgct tcgatttgga agcccatttt tcggtaaagg tgtacggctc
    38941 tttcattacg aacttgaacg tcaagctcca atcgaaaaag tacacccatt tccttcgccc
    39001 aactgatgat ttcttctagc ataagagtgc ctagtcccat tccccaatat tcctgcagaa
    39061 tactgatacc gacttctccc acgtgagaca aacgaaattg actgtctgcc ttgacagatg
    39121 ctgttccaat aatcgtccct tcatagattg caagcagcaa taaattatta ttgctttcgt
    39181 atatataatc caactcttct tctaaggttt ctggtggtaa caggagttct gcttcatcca
    39241 aaactaaaaa ttctgtctcc ttattaactt gtcccatcat caaaagaatg tcttttgcat
    39301 ctcctggcac tgcttcccgc aagatgatcc caacttcttc actcatgatt ttcagcccat
    39361 ttttctagaa ttcgctgttt gaaggtttca ctttgctccc cgtatgagat tagtttcaca
    39421 taccgctttt ctaaatctgt atcacttttt tctaaaatca gttccaaata atcctccggc
    39481 agtgcttctt ctaatagatt tccccattca acaacggaaa gcccatcacc ttcaaaatat
    39541 tcatctaacc ctaaatctgc tccgctagct gctacccgat aaatatccat atgatacaac
    39601 ggaatccgac cttgactata ttctctaata atcgtgtatg tcggactttt gatcatttgc
    39661 gttatcccta atccttgggc aattcctttc gtcaacgttg ttttacccgc acctagatca
    39721 ccagtcaata tcagattgtc acctggcatt gcggaatgac caattgcctc tgcgaattgt
    39781 tctgtcattg ttaatcctga tagttcgatc atttttcatc ttctcccgct cttctttctt
    39841 tttgccagta tatcgcgtaa tgaagttttt ttaaagaaaa aatgaactag tcaagaacag
    39901 cagctgctgt ttttggctag ttcgcgtgta tttgttaatc aatcaatgtt tgtgctgctg
    39961 tgataatcga taatttatat acatcttctt catttgctcc acgagacaaa tcagaaaccg
    40021 gtttgttcaa gccttgtaga attggtccga ttgcttcaaa gttaccgaaa cgctgagcaa
    40081 ttttatagcc gatatttcct gactgcaatt ctggaaatac aaagactgtt gcttgaccag
    40141 ctacttctga atctggcgct ttcagttgtg caactgaagg aacataagaa gcatcaaatt
    40201 gcaattcgcc gtcgatcatg tattgtggcg ctagtttttt agcgatttta gttgcttcaa
    40261 ctactttgtc tacttctggc gatttcgctg agccttttgt cgagaagctc atcattgcta
    40321 cttttggttc gatatcgaac aattctgctg tttttgcaga atctacggcg atttcagcca
    40381 attcttgcgc agttggattc acgttgatcg cacaatccga aaagacatat ttttcttgat
    40441 ctcttccacg taccatgatc atcgctccgc ttgtccgact gatgccaggc tttgttttga
    40501 tgatctgaag tgctgggcga acagtgtcgc cagtcgaatg gatcgctcca gagaccattc
    40561 cgtctgcaat ccccatatac gtaagcatcg taccaaagta attcacatct tttaaaatct
    40621 tttctgcttg ttctttggat gcctttccat ttctacgttc aacaaaagta tccaccattt
    40681 catcccactt atcgtaatta tcagggctga tgatcgtaaa gctagatgtt ttgattcctc
    40741 tggcatgcgc tgcatttctt atttcttctt cgttccctac taaaatgggt tccacaagtt
    40801 cttctgcttt caaccgggca gctgcgccta aaatacgagc atcagtagct tccgggaaaa
    40861 cgattttgat cccacggcga acaattttaa atcttaaact atcaaacaat tccacaagat
    40921 gacctccaga cgtttttata tgtattatca tacactattc cagaaaaaaa gaacagttta
    40981 ttttatctgt atcagtcaaa aatgctggaa aaattaagtt tttcacatac aaagcgaact
    41041 gcactataac aggaaagcgc tgttttatta cactgtttca ggcagttgcc aatcaatcgg
    41101 ttcttctcct aacgcaagga gcgcatcatt cgttttcgag aagggtttgg aaccaaaaaa
    41161 gccacgactt gcagataacg gactgggatg tggagatgtt atgatgatat ggcgactctt
    41221 atcgatcatt ttgatttttt cttgtgccgg ttttccccac aagataaaca cgattggttt
    41281 ttcccgttca tttaattttt caatgatcgt gtctgttaat ctttcccaac ctttcccgcg
    41341 atgagaatac gcttgccctt cccgaacggt aagaacggtg ttgagtaaaa ggactccctg
    41401 tttagcccat gacactagat ttccatgttg aacaggtgcg attccaagat catcataaag
    41461 ctctttatag atatttctta acgatggcgg gatctttacg ccaggttgca cagaaaaaga
    41521 taagccatga gcttgatttt ctccatgata aggatcttgt cctaaaatca ccactttaac
    41581 ttcttcataa ggagtcaatt ccaatgcttc atagatatga tacatatctg gatggatctt
    41641 ttgggacgca tattcttttt ttaaaaattc tcttagatgc agataataat cttttgaaaa
    41701 ttctgaggac aaaacttctt gccaactgtt atgaatgatt tctttcaaaa actccacctc
    41761 ctaataaaaa gaataactca cattttcttc aatcacaagg gacaatcttc accctcagca
    41821 cttgattaat atggtaaact aggaacaaga agcagaaagg aacgataatc attatgatca
    41881 aattaattgc atcagatatg gacggcacat tattagatgc ccatatgagt gtttctcctg
    41941 aaaatgccga ggcgatacgt tttgcaaatg atgccggtgt tgagttcatg gtcgctactg
    42001 gtcgaaacta tcaagaagct cgcgcagctt tagatgaggt aggaatcgat tgtgcgatga
    42061 tcactttgaa cggggcacag gtatttgata aagaaggaaa ttcattgttt accgtgtcga
    42121 ttccaaataa tcaagcaatc tctgttttag atattctaga tgctaacggt atttactatg
    42181 aagtagcaac caacgatggt ctttattctg aaaatcaagc gaaacgaatt gaaagttttg
    42241 cttccatggt ggctacccat ttacctcacc ttacgtataa aatggcgatt gccatggcct
    42301 cagctaagct ggagttattg cacatcacat acgtggacag tattcgtgct attttggaag
    42361 aaaagaatct ggaagtttta aaaattattt gttttcatac agaagggcca gctgtattag
    42421 gtccagttgg aaagcagatt tctcttttag gcgatctagc cgttacttcc tctggtcaaa
    42481 acaatatcga agtgaaccat aaaaacgctc aaaaaggaat tgctgttgcc catgtcgctc
    42541 acgagcgtgg gatttcttta gaagaagtca tgacgattgg cgataacttc aatgatgtca
    42601 gcatgctgca agtagcagga gtcagtttcg caatgggaaa tgcagaaatc gaagtaaaag
    42661 attatgccaa atatacaacg gacacaaacc ttgaatctgg cgtaggaaaa gccatattgc
    42721 gcgcgattgc agaagacttg tagttttatc tagaaaagag ggatatagat gtcagaattt
    42781 ttcattcagg aaaagcagct tggacgtgca actcggacaa ttgtcaaaaa cgaaaaagga
    42841 cattccctgt ttttgatggt tggtcgctgg ggaacaaagg gcgatgcatt gtctctttat
    42901 gccatgaatg gcgatctcgt tgctcacatc aagcagataa gcctgacatt cggtacgcgt
    42961 tttgagctgt ataaagagtt cgaaaaggtg ggaaccatgc agaaaatatt caattggccc
    43021 ggtgactttt attatattcg tagacttcac tggacagtcc aaggtgatat ctataatcat
    43081 caatatcaaa tccatcattt caatcagcaa atcatgaaaa tggataaagc aacacttttt
    43141 tcaggagatt actatgtatt ggatgtctca aatgatgaag atgctccagt ttgtatttgt
    43201 attgctgcgg ttttagatta ctggctctac cgtaaagaca aaagtcgcga taagcctgtt
    43261 tcttaccgac ttaacttaag ttaaaaagat gtacctgaaa tgcggaaata cgcatttcag
    43321 gtacatcttt ttagatattc ttttgcatat gatcataaag atgaccactg atcatccgct
    43381 gaccgacaac tttgaagtca tggcgttcgt ataatttttt agcctttgga tttttttcat
    43441 ccacacttag accgatgacg gagcgattag ctttcttcgc caatttaggt aatgcttcta
    43501 ataatcgcga accgatgcct tgtcctctaa aatcttctga tacactgata gagtccaaat
    43561 accattcgtt gggaaacgtt tctttatcaa tgaacaaacg tgtagacgca tctagctgat
    43621 atttctctaa gataggtacc agtggctgat cgatgattga ttcttcttca tctgtataac
    43681 cgtaagcaac tcctgcaact ttaccgtcta tttcttctac gatacctcgt gaataactgt
    43741 aacgataatt tggatcagtg attgcttctt ctaaaatctc taaagtcttt tgttcccctg
    43801 tctgcttcaa aaatggcagt tccatatctt ttagaatcac taagatcaat ggggcgattt
    43861 ctggagcatc ttcttttctc gcaaaacgaa tcatagtttc ctctcctttt ctccattcta
    43921 acatgcagaa aaagaaatcg caaaatcgtt attttaaaaa atcttcaatc ttttcagtaa
    43981 tgaaataacc atgagtaacg attcttgccg cttcagttcg gcaataaggg cagacgactg
    44041 gcatttcttt atcattatgt tcgactacat tattgacttc ttcgtatgca aatttttttc
    44101 cgcaattagg gcatttcatt ttttccatgt tatctcaact tcctttcatc tttactctct
    44161 tagcttactc ttatattgta aaaaagagaa gcaatatcct tcttctatgc agatatccat
    44221 acctgacggt cctgttctcc atctattaat cggactttat aataaggacg ttcatctttg
    44281 actagaagtg tccactcttt cacttttgct tttttcccgt agtagctgac tgcttccttc
    44341 atcgctgctt gcggttgttt gaactcttcc gttttttcta tatcaaaaag atgttctgcg
    44401 gccttttccg tgtcatttcg tacggttgtt ttcccagtgg atggattgac tgctatgact
    44461 tgtccttcac aaaaaaactg gtattcatat gttgcattcg taggattctc caaatctttt
    44521 tcaactgcaa aatgaatagc agatatgtta tgttcttttg tttcgttttt tacgattgct
    44581 gctgcttttt tcaatgagat ccgatattcc tggtcactaa tatcatccat gtgaaaagcg
    44641 gcattgagca gtcccgtcat accggtaatc cctattacga tgagggcagc aacaccaaac
    44701 atcatttttt tcattcttca ttctcctgtt tctttttttt aaagaatatc aagaaatgaa
    44761 cgaatgaaaa atcgaatgaa acgaaaaaaa agtgacaatt ttgttatctt tattcgtgca
    44821 gttctaatgg caatccgtct ggatcaaaga aaaacgtcat tttttttcct gtaaaggtat
    44881 cttctctaat cggttctgat tcgatcccta aggactgcaa ttctgcaatt gtttcttcaa
    44941 tatcgtctac tttgaaagca agatgacgca agccacaagc ttctggatag tttggtcgtt
    45001 gtggcgcatt agcaattcca aaaatctcca attcagcact tcctagtttc agatctaatt
    45061 tatagtcatc tcgttctttg cggtaatttt ctctgattac ttcaaatcct aatttattaa
    45121 cataaaaatc acgtgatttc tgataatctg aaacaatgat ggctatatga tggatcgttg
    45181 taaggttcat atgagcactc ctattcttcg tttaagctcg gatctatatt aatctccagt
    45241 tccattgtaa atgtgtcaga ttgaaaaaaa tagctgtttt tcctttttat aagaaaaaag
    45301 gcaaaaaaaa cagaaagtag gtcctccaag acactcttcc tgttcccaat ataataaatg
    45361 aaagtaagaa attatatttt caagaaaaca aacagaaaat tatcataaca caaattattt
    45421 ataattgaaa gactagtttt ttttcaagaa aagcatacaa tagattgtgt tagtaaatac
    45481 agaacacact acatttagtg tcttaaggag tcctcataca tgaagtcata ttttcagttt
    45541 ttagctcatc agctaaaagg ctggccgcaa caaaattatt atcttttctt tttcagtctt
    45601 ggctgccagg tcatgactct tgtcaatagt cccatcactt ggctgtccgt tattacattt
    45661 atcggtacca cgcttggtgt attgtgtatt ttatccatca atgcggcaaa atcagtcaac
    45721 ggtattttag gtattttgtc tgcgatttgt tttattatcg ttgggttttc agcaaagaac
    45781 tatttaagta tcggtgaaca gattgcttat atgatcacat tggatatccc cgtattgtta
    45841 agtaaagaat ggaatcataa tatggcttca aaaatccgaa aattcactgg aaaaagctgg
    45901 tttatcgcaa tcatcagtac tttccttgtc tatcttgttt caggattcct gattggtcgt
    45961 tatacagatg atcctcggcc gtgggtagat gccattgctt tttctattag cttgactgct
    46021 ggtatcatca gtttcttgcg ttacaacaac caatattact ggtggttagc ttcagggctt
    46081 gctcaaatgg tcctttggta tatttcattt acgcatggat ctgcaagttt ggcgatgttc
    46141 gtgaacagct ctgtttactt gctgaatgat gtccttgcat ttaccgtttc accttggtat
    46201 aaccaaaaag aacgtgaacg tatgcaaaaa atggaagaag aatactacaa cgcacaacaa
    46261 cacgcataaa aaaactgagc gtgggacaaa agtaaagaac acttttgtct cacgctctaa
    46321 acacgtataa acggcggaat cagaagcaac tccttcggaa ataagctgaa attcacaaaa
    46381 atttgaaaag caattttcgt gaatttcttc ttatttcttg gagttaaacg cttctgtccc
    46441 agcctctatt ttttatagta attccttcag atactttctt gcctcatcat tgaaacgcag
    46501 tgattcttct aacttctgat aatattccaa cgcttgtttc tgagcttcag taaaacgata
    46561 atgttttcct ttccatttgt cgattgtctc ttgcacattt ccagattgga tatctttcac
    46621 tactagttgc catttttctt ttgagactgt acggtctttc ttatcagcag attgtatagc
    46681 ttctcgttct ttacgcaata cttttaaaaa accatttctg actatccgag gaatgctgtc
    46741 gaagaaccct tctgtaaaac catagtgaca atattgcttc caaataaata gatagatttt
    46801 tggttggatg aatcgttggt ttttcgcaaa atattccatc tgagcagtga cttctggtgt
    46861 tcgttgacgt tttgtctttc tcaacacgga aataaatgtt tcaaaataag cattaggatg
    46921 tactggcact tcttcatata cgatggattg ccaatcttta cgtaaaaatg cgcgatagtt
    46981 gatcaagaat tcttctacat cctttactaa ttcttctgca aagtcgtcaa atagttcttt
    47041 ttttatctgt cgcttttttg actgcccatt gatgtgttca cttattttct tgatttcatt
    47101 ttccaatgct tgataatccg ctatgtaaat cggcatttct acttggcgaa attctgcgag
    47161 ccgctgagct aattttatat ccggtaaata tggctgtttc atccgacgat tttggtacaa
    47221 gacaaaacag tatttttgcc atagtccttc aggaaaatcg atattcttct gcttaagcca
    47281 taataattcg tctaaggcca gatcaacttt tgtcattccc tgatggatcg aagctgccac
    47341 tgtcggagag acatgcaggt gatcggcaaa gtggttgatg cctagtttta ggatctttcc
    47401 ggtttttggc gatttaacga tgtattgcac ttttaattct ctaccacact cacaatacaa
    47461 tttttgctgg cttcgttttg ttcgaaaaaa cggattgatc ttgaagtcag aaaacaccca
    47521 atctgttgca gctaaataat gttcttccat aaaacgagag ctgattagat atcggcggtg
    47581 cttatcgact agttcccgct gttttttcgt taattttgca tagatctccc aacgttgact
    47641 gcttgtgtat tgtttagaaa ttttgatggg atagcttttg ctgatttctt ttggaaacca
    47701 ttcttcaaag acggattgcc attcttccac ggctgtttct ttcctttcta attacaaaaa
    47761 gctggctact aacataacgt tagcaaccag ccagtgtttc ttgctaaatt agtgagttgt
    47821 tccggcattt ccggaaatat cttctttatt ttctactgct gcttcaactg cataagtcaa
    47881 agaagaagca atgtcttcta aagacataga aggcgtaccc actggacgat cgatcacttg
    47941 atcgggtgag aatggcacgt ggatgaaccc acctcgaatt gccgggaatt gtgtttcgat
    48001 caaatgaagc aaacgataca tgatatcatt gcagacaaat gttcctgctg tataagagat
    48061 gtacgctggt agaccatgat cttgtacatt ttttgtcatt gctttgattg gcaatgaggt
    48121 aaagtaagcg gctggaccgt tttcttctaa agccgtatcg aatggctgat ttccttcatt
    48181 atcagggatt cttgcttctg ctagattgat tgcgacacgt tcgaacgaga ctgctgaccg
    48241 cccacctgct tgtccgacac agatcacgac atctggttgg tgctgttgga tggcttcttt
    48301 gactacttga ctgctttttt cgaatacggt cggtacttcc actttgatga tttcagcacc
    48361 gctgatttca tctggcattt tttttactgc ttcataggct ggattcactt tgtccccacc
    48421 aaatggatca aaacctgtta ctagtacttt catctgttgt tcctccgtcc gattgattta
    48481 acatatggtt atcttttatc ataccatttt ccttgaacag cgtaaataaa ggaaacaata
    48541 gtttaaataa cataacagat caaacttaat atattcttat aaaaaaatag tgttccacta
    48601 caatgttaga agaggttgcg acaattattc tgtcacaacc cctctcttct attatttaaa
    48661 tagaatcata taagcaattt ggaaaactag cataaataac gcaataaaca actggttttt
    48721 gatcactccg tatttgtctt tcatctccag catcgctaca ggcacgatat tgaagttagc
    48781 agccatcggt gtcagcaggg tcccacaaaa accgcaagtc aatgcaacca ttcctattaa
    48841 cgctggattc gctccatgac taaatacgaa tggtgcaccg atcccaaccg tcatcacggt
    48901 gatggccgca aatgcattcc ccatgattac cgtaaatatc accatgccaa gagcgtaaat
    48961 gatgatgccg atgttcacat ttccttctgg aacgatcgta cctactgcat tggaaatcac
    49021 tgtcccaact ccagcgcttg taaataccgc acctagagaa gctaaaagca ttggcaacat
    49081 gcttaacggc cctactgtgc ccagcatatc tgctgcatca tctaaaaatg tacttggtcg
    49141 attatctcga gaaaagaaca tcaagattag catggctgca aaaacaccga cgcccacgcc
    49201 gactaaagca cctaaattgg taaatagagc aaacaagatc gcaaagacac cgatactcaa
    49261 agctggaata aaaattttca ttcctagttt gtctgacatt ttttccatat attcttttga
    49321 tggaagccgg ctttctcctt tgctgacttt cttagcaatt gctggtatgg tcatcgcaaa
    49381 gatcaagcca ccgttcacga ttgccggaag ccatcttcct cctgcaataa ctacccctaa
    49441 gaccgtccag aaaaaggctg acccataacg atgaggattg gttttatctg ttaaatttct
    49501 tactccagtg taaatcaata cgagtcccat cacgatataa aggatctcca gtaatttatc
    49561 gcctaataaa atatcaggat ttgtaaaaaa gtccatctta ttgccccttt cctggataat
    49621 atttcttcgc taatttcttt tctttaagat agaagtagac acttgccaca actaaagccg
    49681 tgatagccac tggaacttcc actaaagcaa gctgtcccaa tgttacgtca tatcctagat
    49741 ctttcagtgt tgattggact agcaacgccc ctgctcctcc gatgaatagt acttggccaa
    49801 agaaccagca gacattttcc atagctgaag ccataccttt tagttcttct tcatgcttag
    49861 gatggacttc taaccctttt gattcgatgg tccccaatgc catcggtaaa atgattggac
    49921 gaacaaatcc agcaactcca ccaaaactca cgttaaaagc cgcaaagatc attcgaaaga
    49981 tcccataaat atctacaatc ataccagcag atactttctt gaatcgcttg atcaaggaag
    50041 ccgctgattc tttcagacca tttctttcaa gcgttcctgt tgccaacata atgatgataa
    50101 aaatcgccat cccgcgattg tttacaaaac ttgtacctaa aagttctaac attccttgaa
    50161 tgccaagacc gccagtcaaa gctgtaacaa ctaaagcaac cattacgatc aatatcgagt
    50221 ctaatttaaa tgcaaacccg agaataacaa tcaagacgcc taaaaggcta agataatttt
    50281 ccatatattt tcctccataa aatgacaata tttttttaat tataaagcaa aacacataaa
    50341 aaatatagtt gttttctcac gaaatagaca ctatttttaa atatttttcg ttattttttt
    50401 atcacaaaaa ttatcttact tattgtaagg taaagctttt tttaatttat tgcccgataa
    50461 tatatagaaa taaggtctag ttactgtttt ttttaaatga ttaataaata acaacttctt
    50521 tctatgaaat tgcaaagcat tcatcttctt ttccgctaac gatatatccg tcagtgcttg
    50581 gtacacttta ctaaaaagta tgagattgcc gatatctgga taggtgtgct atactacaga
    50641 aaaagatata caatctgcca ccgggtagga taaagaggat gatcattcca ttaggtcttt
    50701 gaagggatga ttttcctctt tttgtgtatt tttttatagt taaggaggaa tgtaagtatg
    50761 gcatggatgg aattaatcat agcaggaatt ttggaagtat tctggtcaac gatgatgaaa
    50821 tggagtgatg gtttttctaa aatcaattat tctttttaca cagtgattgg catgattgct
    50881 agtttttact ttttgtcaaa ggcaatcaaa agtttgccga tgagtctctc ttatcctatc
    50941 tggacaggga ttggcgcagt tggttcggtc ataattggtg tggtcttgtt tcatgataag
    51001 ctgaatcttt ccacttggtt ctttgtgggg atgctactca tcagtatcat tggcatcaag
    51061 attactagcg gccactagac acttggaata agtactgatc agaaaaaata agccttttta
    51121 tttaatattc aattttttta tgaaaaaata agaaataagt ccaatgacct agcgacttct
    51181 ccactcatca ggtgtatgct tgtactatct atagaaaagg agtgaatatt tttgaaaagt
    51241 ctttcggtcc aagaattatc caagaacttt ggtcacaaac aagccctcag cgatgtcagt
    51301 tttagcttat cccctggcaa aatcgttgga ttagtaggtc ctaatggcgc tggaaaaaca
    51361 acgatcatga aagctatttt aggactgatc cattactcag atggaacaat ctgtattggt
    51421 gaaaatgaga tttctccctc tagtcataaa gggttggaac aagtaggagc attgatcgaa
    51481 tacccgggta tctatccatt cttaacaggc tatgatcatc tgaagttatt ctctgaaacc
    51541 aacgatgtat ctgctatcga cactatcgtg aatcagctca agatggaaaa gtacattcac
    51601 aaaaaagcga aatcctactc gttgggaatg aaacaaaaat tgggaattgc tcttgcctta
    51661 ctgaaccatc cgtctatcgt tattttagat gagccgatga acggtttgga tccacaagca
    51721 acaagagatg tgcgaaaaat cattaccgac ttggctactc agggcacctc tttcttgatc
    51781 tccagtcact tactcagcga gcttgaaaaa atggtcgatg agctgatcct gatcaatcaa
    51841 ggaaagatca tcaaacaatg tacaatggct gaattgaacc aaacagcgca agatttcatc
    51901 gttatctcta caacaaatga tctagctgct cgaacgatct tgacagaagc tggatatact
    51961 ttggaagatc ctgataaaat caagctttta aaagaaaacg aagaattatt aggaaccgtg
    52021 atccagctat tgtctgcaca aaatatccat gtgacagacg tccagcatct gacgaatgat
    52081 ttggaatctt ctctattgga aattctggat tcagtaaagg gggaagaaga aaaatgacat
    52141 tgcttgtaaa acaagaatta tttaaattga tcaagaaaaa gtcaactgct gttttatctg
    52201 ttctattagt tgttttgctc ataggaacag cacttctagc caaaaaatac acgacgatca
    52261 ttgatccagt tgaaatgact gctcagcttt ttagtgccac atcttggatt gtctttatca
    52321 tgattgcagc tgcaagcacg atcatttcga tggaagcaca atatggtaca ttgaaaaatc
    52381 tcctttatcg aaagtattct cgaggagaaa tattagtaag caaatggatc acattagtta
    52441 tttattctgt ttatttatac cttttagcta ttattgtcac tgtgttgatg aaactgattc
    52501 ttttcccttc gatttccttc acggagaagg tttctactgg tcaaacactg atccaaagct
    52561 tgttcactta tactttgggt agttatatcg gtttatggct gattttaagt ttagtgttga
    52621 tgattgcttg ctttatcaat agttccggcg catccatctc agcaggaatc gtcttttatt
    52681 ttgcttcgtc aatcatatct ggtatcctta ttgcactcat ccaaaaatgg gagtggatca
    52741 aatggaatcc gatcagtatg ttgaatctgc aaaaccaaat tggaaacgaa gagatcatga
    52801 agcaattgac tcatctttct actaatcaaa tgctattcgg taatttagct tacatcgttt
    52861 tgttcttagc attaggatat ctcgtattta agcgaaaaaa tgtatgatga ctcatcaaaa
    52921 aagaggctgt gaaagagacg ttcagcctta ttgccgattg gctgtctctt aaacaccgtt
    52981 tattctgaaa aaggagctgt gacaacattt gtgtcacagc tcctttccta gtatgttttt
    53041 gaataaacga caggctcaca acctctcttt atacttcttt tatacttcta tacgtgaagc
    53101 atcccagtgg caaataaaac cattgcaatc actccgacca tcgtcacacc tataagtaaa
    53161 atcttatcta agtggatatg ttgtacaggc tcgttttgct ccttacgtgc tttgaggtaa
    53221 aaataaatgc ctggcaagaa aagaacaaga acaagcatta cttcattaaa ggctacgact
    53281 agcatagccc atacttgaaa ggcacttgct aaaagcccta ctaaaaattg gacccattct
    53341 ttccgctgat aagaaagttt catttggtac aatcctaaga aaagccacgt gaagaaaata
    53401 gctgctgtac caagtgtgta agcaaagtta taagcactgt cagtgaataa taatgaaagt
    53461 aaaaagacat tcgtacataa cgtcgtcaat acgatagcat aagttggtgc cccatttttg
    53521 ttgagttttc cccatgcttt aggcaaaagt ccgtcttcag ccatgtttcc cattgtttca
    53581 atcggtaaga tcgtccatga gagccaaaca ccaactaaag aaatgatcaa accgccgttg
    53641 atcacgactg ctccccattt accaaccatc atttcaaaca catagcccat agcaggctgc
    53701 gccttgatcg tttgcagctg attcatcgtc attgtcccat atggaagcat ggaaaccaag
    53761 acgtaaataa taatcaagcc gaatatccct agaatcgttg ctttcccaac atctgattgt
    53821 ttttttgctc gtgaacctac gacagaggct ccttcaatac caacaaatac ccaaagcatc
    53881 accatgatgc aactcaatac ttgactggaa aacgggatcg gctgtccatt cgcattcaat
    53941 ataatgtcgc tagaaaagtt atcaatgaat tgttggatcg aaaacgtgct gatagctact
    54001 acaataaata aaaataatgg cactaattta cagaatgtga cgatagcatt gacgaaacta
    54061 gcattttcga ctccccgatt cactagccat gcatatcccc ataaaaagac tgtactcatc
    54121 acgatcgatg ccagattttg cccaccttca aatactggga agaaatatcc taatgcgctc
    54181 atcaacaatg ttgcaaaagc tacgttgcct aaccagcatg tgagccagta accccaaccg
    54241 ctgataaaac cagcgaaacg gccaaaacct tcttctgcgt aactaaagat cccgcctttt
    54301 aaatctggac gttttttatt gatattattg atcgacaagg agagcatcaa cattgctgtt
    54361 cctacgagta cccaactgaa aatagctggg ccgccagccg atccggagat gtccgtcata
    54421 ataccaaata cgccacctcc aatcgctgaa ccaattacta aggcagcaag tggaattaaa
    54481 ccaattcctt ttttctgttg ctctgtatcc atgtaagcat cctccaaaat aaaaccgctt
    54541 ttatcaaaaa gtataacaaa ccttttttat ttttacttaa ttaataaaaa ctttaataga
    54601 aatataattc taccggcttt tttctcatta tacaagcaaa gcgcctagtc cctttccaaa
    54661 ttacaccacc aaaaaactta aaaaagatgc tatactaaaa ggaaagaatt ggaggatgat
    54721 ccatgaacat tttatatata tcgatttcag gaaatacgcg tgcctttgcc aaacatctag
    54781 cagaatatgc tgaaaaaatg catgcagaag atcctgtcaa tcctgaagtt actttaaaag
    54841 aaatccatga aaatagtgat tttacgaaag aaacagaacc attttttact ttcgttccta
    54901 cttatttaga cggcggaaat ggtttagata acggtgatac agaaatcttg accgaaacga
    54961 tgcgtgaata tctggaacat gaagacaatc ataaactttg tcttggtgta gtcggtagcg
    55021 gaaataaaaa cttcaataat cagtattgtc taacagccaa acaatatgca caaacatttg
    55081 gctttccttt cttggcagat tatgaattac ggggaacacc atctgatgtg acacgaattt
    55141 atcagatttt agcagaaaac aataaataat aaaaaagaag aagctgaaaa atagatttca
    55201 gtttcttctt tcgtttctat tgtttctatc atattaagct ttgacatcca tcacaggtgc
    55261 ttttgctttt gctttacctg ttttttccaa gacaaagttt tttacacgat ccatattggt
    55321 taccaagacg atcatggatg tttctttgcc tgctgctttg atcgcttcta agtcagcttc
    55381 tgctacaagc gtatcaggtg tcacttgctg cccttctgtt actttcacat caaatggcgt
    55441 accgcctaag tcaactgtgt tgattcccat atgaagcaag atttctaaac catttggcgt
    55501 tgtgatccca atagcgtgtt tcgttgggaa gacagagctg actaccccag taactggaga
    55561 atagatatgt ccgttttctg gttctacaaa gtagccttca cccatcatct tttgtgcaaa
    55621 aactggatca cttgctttat ctaaagaaac aactgttccg tcagcaactg atgagaggat
    55681 agtcacactt tcagctgaag tttgaggtac tactttttca ggcacttcat ttactgtggc
    55741 tgtttcagtc gctaattctt ctttttctaa acggtcttta ggaataccga agaagaatgt
    55801 agcaacgaag ccaccagcat aagctgccaa taatccaagg atgtagccta accatttacc
    55861 gtcagagatc aatgggatca aagcggctcc tgaaggtcca atagcgatag ccccgacatt
    55921 tccgatcatt ccgatcactg ccccgccgat acctccaccg atacaagcag taataaatgg
    55981 gcgtcctaga ggtaatgtta ctccgtaaat caatggttcg ccgattccta ggatcccgac
    56041 tggtaaagct cctttgatca tttctgttaa ttctttatct tttttgcagc gaatccataa
    56101 tgccaatgct gcacccactt gtcctgcacc agccatcgca agaattggaa gcaatagcgt
    56161 acgaccagtt tcatcaatca tttgcacatg gattggagtc aaaatttgat gcagtccgaa
    56221 cataaccatc ggcaagaata atgtgcctag aacgaagccg gcaaatgctc caccaacgcc
    56281 aagtacccag ttgatcccac cgaccatgcc atcagaaatg aaacctgcta aaggcatgat
    56341 gaagaaaatt tcaatcagac cgatggcaat caacgaaaga gttggtgtaa cgatgatatc
    56401 taccgcatca ggtactactt tatgcagttt tttctcaacg attgacaata gccaaacagc
    56461 gaagatgaca cctaggatcc caccttgtcc agctgcaaga gcttcaccag taaataagtt
    56521 tttcagtggt gcttccggat tcatccctgt cagcatcaca acggccccga taactccacc
    56581 aagagttggt gttgcaccaa aaacttgtgc agcattgata cctgtataga taactaggta
    56641 gctaaacatc ccgtttttca agatgttcat cacatcgata tattgttgcc atgttgctgc
    56701 atcaagtgtt ccggctgtga ctaagtttgc taaaactgcg gcaatccctg ccacgatccc
    56761 agtaccgaca aatgcaggaa tcattggcac aaagatatta gaaatgtctt ttaataccga
    56821 tttgatttta gatggttttt gtttcgattt ttgtgccgct ttcatttctt gtgcccgttc
    56881 gtttacacgg tcttttccag atgctgatga atttgctgta gctgtactta cagaagaaag
    56941 tttttctcct aatttcacgc ctgccaaatc aaccatttgc tgtgctactt tgttcacttt
    57001 cccaggtccg atgatgactt gaagctgttc atcttctact acaccaagca ctcctggaat
    57061 cgcttttaat tcagagacat ttacaagatc atcattgatg atcttcatac gcacacgagt
    57121 catgcagtgg acaatgcttt ctacattgcc catgccgcct gcccctttat aaatttgttt
    57181 tgccagttct tccaaagtca gttcgttttt tgccatggtc ttttccccct cataaggtcc
    57241 cttttacaaa tccgtttgct tcagctaatt ttgcttgagc ttcctcttta tcactatttg
    57301 tcaaaatcat gacgatagcc agcttaacat tttgatctgc ttcttcaaag tacttttcag
    57361 ctgtttcgta atcagcttct gtcgcttgca tgatgattcg ttttgagcgt tcgattagtt
    57421 tttcatttgt tggtttgaca tcgaccatca agttattgaa tactttacct ataccaatca
    57481 tactgatagt agaaatcata ttcaagataa gtttttgtgc tgttcctgac ttcaatcgag
    57541 tagagcctgt caaaaattct ggacctgcat cgacttcgat tgggaaatcc gcgtgtttac
    57601 tgatttcggc ttgtttattg caagaaatcg ttcctgtgac agcaccgatc gattttgcgt
    57661 aatctaatcc accgatcaca tatggtgtac gaccgctagc tgcgatacca ataactatat
    57721 cattttttgt caaattcagc ttgattagat cttcttgccc tagctcataa gaatcttcgg
    57781 ccccttcgac agctacagtc attgcttctt ctccaccagc aattagacct atgaccattt
    57841 ccggttctac accgaatgtc ggtacgcatt cagcagcatc taacacacct agtcttccac
    57901 ttgttccggc tcccatataa atcagacgtc cacctttttt aaaggactca atcgtgttag
    57961 caatcactgg ttcgatactt gtcagttctt tttcaaccgc agcggccact ttctgatctt
    58021 ctttgttcat tagttgaacg gcttgagaaa tactcatctc atctaatcca aaagtttctt
    58081 ggtttctgcg ttccgttgtt aggttctcta aattgatttt gctcattttt atcttccttc
    58141 ttttcttata aattgatagt tcataccagc tttgatttgg ttgatcaatg gtagctcttc
    58201 tttgataact ttagctacta cattcacttt ttcatccgct ggcaaatcat atttggttaa
    58261 ttggatctca cccatatagc gcaaatactt ttcgttatct aaagtaatag accctttcat
    58321 acgcgtagct gtatttcttg ctgggatagg cggaatctct cgaaaacgtg catctacgct
    58381 tcgtatgaca tctcttgcat cgtcttgccg attcgtatgc ttccctaata tatattcgta
    58441 aaattcttca tctacaggtt ccgtatggag caagactgtc tgttcttttt ggaaagaagc
    58501 aaattgctcc tgaacgtttt ctgacagacc tgcatctccg atgtaaacaa tatccgtgtt
    58561 acttgctaat agatctagag cgcctgcaag aggatggatc cctcgatgtt cttccaaagt
    58621 tggcaatcct tgatatagtg ggcctctcaa ctctgtatct cctggtacaa aaccttggac
    58681 aaggagacct tgaattttga gccattgatt ttttttctga taccattctt tgtccagccc
    58741 tgtttcggga cgtggataat aattatgcca agcttcaatc tgtgagaaat cagcttctgc
    58801 ttctttcaat tcatcgatat ctttaggcgt gatcgtgcta gcattcaaac tgattttcaa
    58861 ttgatgtgac cagtcggcaa tctgctgatt ggaaatatga taatccattc ttaaacctgt
    58921 tacaccaatt gctttcaaag gcgttagatc ttctaatgaa aaacccgctc gttccaatgc
    58981 ctctcctgaa atatcgacca tcaattctag tttattcttt ttcgcttcgc ttcctagttc
    59041 gatcaatcgc ttttgatatg ccgaaacatc atcttctggt atatgcatgg aagtgaaaat
    59101 accgacaaag ccattggatg ccatttggcg gatatactgt ttcttctctt ctgacaaaga
    59161 atcgttcata aatattgaaa agccaaacat attatccctc tttttctgta tccgtcttca
    59221 tttctatgac tagagtatat atctaaagaa acaaaatttc aatactttta ttaaaataat
    59281 taaatttcat ttctaaaggt tgagtttata ttatcaaaag aattgtcata acctaaaaaa
    59341 ggcactgcta agcaaaagca gtgccttgaa atattttatt taaataacac aaaaacataa
    59401 ttactcataa gaaaccaatt ctgtattatc taccatgaat gtaaagaacc cctcattagg
    59461 catcggatga aaataagcat tgatcactct tatcaaggca ttatggcaaa ctaacagata
    59521 gacattttct tcgtcttcga tgcattcttt caataaagga acgatccgtg catacacatc
    59581 taagactgac tccccatttg ggaatcgtac agcgaacgct aaacgtgctt tttgaaagtt
    59641 ctcatctttg cttggcagtc catcataatc cccaaaatcc atttctacca atcgttcatc
    59701 aacggtcagc ggcaagctga gacgatcagc aactgcttgt gctgtatctc ttgctcgttg
    59761 aagaggggaa tggatgattt tcgtgattgg aacaggcaaa tctactacct tttctgctag
    59821 tttctgtgcc tgcatctgtc ctttttcagt cagcggcaca tctgcccgtc cgcaaactaa
    59881 tccttgtgcg ttccaagttg tttctccgtg tctcgttaca taaagcatgt gattctctcc
    59941 ttcgttggca aagttcccct taaccatacc ttgttgttct tgagattaca agggttagat
    60001 tctctcaaga gaaataatct cagtagatac tttatccagg aaggtttgat catgttccac
    60061 tagtaacatg gcaggtttca cgttcaagat cagttgttct aattgttctt gattgaagac
    60121 atccaaataa ttcaatggtt catcccatgt atatagttca gctggctgtg ataaagattt
    60181 agccaattcc acttttttcc gttggcccat actcatctgc tcgatcttgt tatgaaaaac
    60241 atctctttcc atcccaagct ttcggaggtt gttcaaaaat gcttggtagt ctacttggtt
    60301 tttctctgca aattccgcca acgttcctcg attgtcttca taattttggc ttgcataact
    60361 aatgctcaga tgttttggct ggtatttttc tcctataacc ttgccgttga atgcccccag
    60421 aagataatgg ataatggatg actttcctgc accgttagga cctgaaatcg ccacccgctg
    60481 atgaggctcg attgtaaaat gaattggctc gaataacaga ttttcatacc ctaattgaag
    60541 atcttctacg cttaaaagtc gcttatggtg agacgcttgg ctattcatcg tcaaagaatc
    60601 gatatattcg atatctttta atagtttttc tttctcgctg atctgggtct ccatccgatt
    60661 cacgattgct ttggatcgtt tcatcgtccg tgcagcatca gcacccactg ctcctttatt
    60721 cactcgtcta gattcagtat cgatgaatcc gacttgtttc tttgttttat ctccttctcg
    60781 ggaacgagac cattcggctt tttcagctgc tgttttcttt agcctactga cttctttttt
    60841 caatttttca ttttgagcca tttcaaattc atcacgaagt tttttctgtt cttcatagat
    60901 agagaaattc ccttgataaa gttccagttg acttttttcg attgctaaaa catggtccac
    60961 tacttcatcg ataaatcccc ggtcatggct gaccacgatg aagccttgtt ttttcttttt
    61021 caaataagcc gctacttgtt ttctaccaga gatatccaaa tgattcgttg gttcatcgat
    61081 taacgggaaa tgagtgtcat ccacaaataa aagtgccagt aggacttttg tcttctctcc
    61141 ccccgatagt gtgctgaatt ctctccataa gatttcagga tctgtttgca tcaattggag
    61201 ctctctttcg atttcccata tctcaaaatc cgtaatatca tttaacacgt aataggttaa
    61261 acgttcttta tcttttgtct gttgcgggaa ataggcaaat tcttgctgat ggattacttg
    61321 cccttgataa ggtagtttgt tttgtagaat attcagtaaa gttgtctttc ctcgaccgtt
    61381 tcgtccgata agtcctagtt tccattgtgt gtcaaaattt agatttgctt gttcaaataa
    61441 taatgtgcct tggctgtcgt agccgaatgt cagatttttt atttcgattt tagacatttt
    61501 ccatcacctc gtaaaaaaag accagtccta ttttcagaac tggctaaaga ggatgcaagg
    61561 gttggataca cacaaaaaga cccatacatc gaaaaaacca agccaatccc gaaaatctgc
    61621 acactgcttc cttgtctcca caaggtacag tctgaatgca gctttcatca atcgacttaa
    61681 tttttcaatg cacggatccc tcactttgtc ctatatttga aattacgata gcataaagaa
    61741 aatgattttg tcaactactt cgggaggatg gtgaaaaatc tgctaagtgt ctgtcctaag
    61801 atttttgttt tttctaatgt ttgcctgtgt tccattgctt cttctaaacc tattggaccc
    61861 aaatgaatac ttaagacaat tgggagaaaa tcagaaagtc cttctagctc ttggtctcta
    61921 cttccgcaaa tagcgattat tggttttcga tatttttttg caagcactgc tacaccgtat
    61981 ggaacttttc cgtggatcgt ttgctgatcg atccgccctt ctcctgtaat gatgacatct
    62041 gcttgttcga tctttttttc caatccagtg atttggctga ctaaatcgaa accagaaacc
    62101 atcttcgctc ccaacaaaaa aagggctcca ccaataccgc ctgctgctcc acttcctgga
    62161 atatcatcta aatccacctc ccagaaatct tttatttgct gagcaatctt tcctgcttgt
    62221 ttatctaaga aagctagcgt cgtatctatt cctccttttt gtcttccaaa ttgccaagca
    62281 gctccttgtt gacctgtata tggattggta acatctgcag cgataatcaa ttttacttta
    62341 gaaacaagaa cgtttcttcg atcaaaatga agttttttag tagataataa aggatttcct
    62401 tctgtgtacc cttctaaaga agcacccaag gattggagta atcctagacc accatcgcta
    62461 cacccgcttc ctcctaaagt gacaataatt tgttctactt cttgaagcag tgcatcttta
    62521 ataagttctc ctaaggcata actggaagca agtcggatag tttgatccgt tggtttatca
    62581 agtagatcta accccaatgc ttgtgcagat tcgatgactg cggtgttttt tccttgccaa
    62641 gttgtcaata aatagctgat ttttcgctga cggaataaga gatccatccc atcaatggta
    62701 cgccatgttc ccctgagcgc gtaatagatt gcttctgcag tattttctcc gccatctgca
    62761 atcggcacat tgatttttct tcctttacga tcttcccagc catttagaac tgcctgattt
    62821 agttcaaatg aagaagcact tcctttaaat gaatcaattg ccgccaaaat atccatctgt
    62881 atccctcact ttcttcttaa gtaagacact ttttttcatt tttttcaaac aaaacaatgc
    62941 tattttcttc catttttcta tatactaaaa gggaactcat tgaataaagg agagaaaaaa
    63001 catgaaaatc gcaatagctg gggccggagc aatgggcagc cgaatcggat tgatgctaca
    63061 tcaaagcgga aatgaggtcc tcttgatcga tcgttggcct gctcacattg aagccattcg
    63121 tacaaatggg ttgattgctg actttaacgg taaagaagtg gtcgcaaaac tgccaatcta
    63181 ttcaccagaa gaaatcatcg aaagcaacga acacgtggac ttgatcgtag cattaacaaa
    63241 agccaatcaa ttagatgata tgttttgttc gatccaatcc attattactg acaatactta
    63301 tgttttgtgt ttactaaatg gattaggtca tgaagatgta ctggaaaaat atgtgccaaa
    63361 gaaaaatatc ttatttggga tcacgatgtg gacagctggt ctagctggtc ccggaaaagt
    63421 cacattgtta ggtgatggag aaatcgaact agagaacttg gaaccagaag gcgaagcatt
    63481 tacaaaaaaa gttgtagaag tctttcaaga agcaaattta aatccgatct atagccataa
    63541 cgttcgttat tccatttggc gaaaagcttg tgtaaatgga acattgaatg gtttatgcac
    63601 gattttggat tgtaatattg ctgaactagg cgcgcaaaaa gcggcagaga gcatggttcg
    63661 aacaatcgta tctgaatttg cttctatcgc agcaaaagaa ggaatcatac tagatcaaga
    63721 agaagtgtac caacatattg cttctactta tgatcctgac aacatcgggt tgcattaccc
    63781 atctatgtac caagacctga tcaaaaacca tcgtttgact gaaatcgact acatcaatgg
    63841 tgccatttgg cgaaaaggac aaaaatatga tattgctaca ccatattgtg cctttttgac
    63901 ccaattagtc catgcaaaag aaggaatcct tggcgcagaa taaaaggctc tctgatgaga
    63961 atcagctgaa tcagcagctg gttctctttt tttaagccca ataaaagatc aaaaagaaaa
    64021 cacaactctc atgatgccat aagaattgtg cttgtttgtt tcagtacata atctcttcaa
    64081 aatgtaggtt ttttatttgt tttcaacaga ggagaggtca tattcgtatt gctcataaat
    64141 agtggaatcg ttagtgataa atcgttttgc ccaattttct gcatcataaa attccaatag
    64201 ctctgatagg attggcttaa atggtgtatg cagaaattcc ggtaattcat ctaaatcacg
    64261 ttctcgaagc aaaaaaatat tttcaggacg ataaaaatga taatgagcaa tcgcttgatt
    64321 atccgtcact agtttctttt gaaaatacat ggattcaaat gtccgcaaag tcactccttg
    64381 ctgaccctcc cgcaacagtt ccagaatccc gcgcgattcc cctgtttttt tcaggtactc
    64441 ttcataagta agatatccag gttgttcatt ccctcgatgt ggaagaatga aatagttggt
    64501 cgtaacatct ctttttataa attcctgctt atagctttct gctcgttctt ttctcccatt
    64561 attcgttgca ccaaaaaata gatccgtctt tggttcgcta gaagaaaaat tcatatgttt
    64621 cgaataaaat gaactattat gtttcagccc aagttctttt gcttccaaaa aatcaaaatg
    64681 ataaatctca tcgattgccg gttcatcttg tgcctgcttc agcatcgcct cgtgttctgc
    64741 tttgaagtga ttccaaaaaa ataacacaat ttttgcattg gtaaatgggc gcacgcgtcg
    64801 agccatctcc atatcaaatc cataatctaa aaaaacgatc agctgataat ttgccaactg
    64861 ttgtctagct gatttaatga attccgactg tagtaaatct tttccggacc aaacatctaa
    64921 agagcggatg gaaggcaaaa aataaagtga tttatttttt gcaactagca gtacgtcatt
    64981 tttgttcatc ttttccgcct cactttctct gtcacttttt cctatgatag cctgtttaaa
    65041 tagtaaaaag ccagtaaaac gtttcctata tttgtatgaa aatttaacat ttgtatgaaa
    65101 atatgatgaa ataaatcatt cttctattaa aattcgccta aaagttttct gaatagttgt
    65161 aattgtctga aaatttgtta tcattagtca ttgttaaata ttgctattta ttcttaatat
    65221 aaattttgat tgtgaattta aaagaaagag gtcatttatg gaagataaaa aattgaaaaa
    65281 acaacttagc tccagacata tcaccatgtt agctttaggt ggagcaatcg gtgcaggtct
    65341 atttaaagga agtggcgaag cgattgggat cgccggccct tctgtattga ttgctttttt
    65401 gattggtggg ctgattttat atatcgtgat gaaaggtctg ggaaaaatcg ttttaagcgg
    65461 tggcgacacg catcacggat tatctggttt gatacgccct tatctaggtg ctcattctgc
    65521 tgattttact gattgggtct actggtctat gtggattatc aatatcatcg ctgaagctgt
    65581 tgcagctgct tcctttttgc agttgtggtt cccgcacatt ccagcctggg tatttgtttt
    65641 tatgttggct gttttaacta cgatcatcaa tctttattcg gtacggttat tcgcagaaac
    65701 agaatattgg ctggcttttg ctaaaatcag tgtcattatc ttactgatca tttttgctac
    65761 ttatcttgtc ggtcagcaaa tgttgggcac aggcgttttc cctacccttc agcaattgac
    65821 tgaccatggt gggtttactc ctcatggtat gaagggaatc atcagttctt tgcttgtagt
    65881 tatctattct tacggcggtt ctgaactgat tgctatcacg gtaagcgaag cagatgatcc
    65941 taaacgtgcg attcctaaag caatcaaagg tgtcatggga agaatcattt ccttttacat
    66001 cattcctttg tttttgcttt tgattctttt tccttggaat actttagcag gcacgaatgt
    66061 cagtcctttt gtgatggtat ttgaaaaaat gaatatccca tttgcagcgg atatcgtcaa
    66121 ttttgtgatt gtccttgctt tgttctcatc tatcaattcg ggtgtgtatg catcttcaag
    66181 aattttgttc ttccgtttga aggatcgaaa aggttcctct agaaaactag ctgttttaaa
    66241 caagcatcaa gtaccgcaac gtgctgtttt attttgtacc agtgttcttt atcttggtgt
    66301 agctctttct tattttgtcg gtgacaaatt atttggctat ctggcaggtt ccctttcgta
    66361 tacagtatta ttgatctgga tcattatcag tgcggcatcc tttgtactgg cactaagaaa
    66421 aggaacatta tgggataaag gaatcagctt ttttgcatta gctgtcttag gattgatttt
    66481 ccttggtatc ctgttcacga actccattgg ggtaactgta ttgactggcc tgctttacct
    66541 gttcatttat ttcagttatc aaaaaaagaa tgatgcgttc gtattgacga atgaatgaaa
    66601 tcgatagaaa attttatttt atttatgtgg aatagatgga gctattgaag aaaggagttg
    66661 tgacaaaagt cttgttgcaa ctcctttttc cgaataaaca gtctcatgac ctcttggtaa
    66721 acggtgttca aaaaccctct gtgcaaaata attgattgtt ctccatgctc atgacatgat
    66781 agaagaaagg aatgaaaaaa aggagtttgt tttaaatgaa aaagtattgg aagtttttgt
    66841 tgatgatcgg tgtttcaacg gtagttatgt ttggtatgat gtacttgaat gtctatgcgc
    66901 tcgatcatat cttcttcagt cgtacacgag tattcatggc gttgatgatg ggtgcagtca
    66961 tggcagtcat catgctgttg ttcatgtgga aaatgtatga aaacaaaaag ataaatgtta
    67021 tgatcttagc cgctagtctt cttgtttttg ccggttcctt gtttatggta cgaagccaaa
    67081 ctactgtcaa cgacacagct tggatgaagg ccatgattcc tcatcattct atcgctatcc
    67141 tggcaagtaa acgagctgat ttaaaagatc ctgaagtaaa aaaattagcg gaagaaatca
    67201 ttcaggcaca agaagaagag atcgacaaaa tgaaaaaaat gatcaaagaa atggaatgac
    67261 cattatccgt ccaaataaaa aaagaggatg ttccagaagt tatcagcttc aagaaataag
    67321 aagaagctac ttctggaacg ccgtgaataa ggggttgtga aaaagctgcc ctgcatcaag
    67381 taataagaac agccaaacaa aaatagcttc tcctattttt cgtttggtta ggcttattac
    67441 cgcagatgca agcttttgaa caccgtttat taagaggttg taaaatcagc gttctgacct
    67501 gagtattaga gagacaaatg gaaaaatagt tcctcatatt ttgccatttt ttgagctaat
    67561 accgagggtc agctgattga acaccgttta tcgagaggtt gtgaaaaagt cgcttagttt
    67621 cgcgtattaa gaaaaatttt gtgaaatggc tttccacatt tttgtataaa tttggcttaa
    67681 taccgagaaa ctggcttttg aataccgttt attcgtaaaa gggattgtga caaaagtctt
    67741 gtcacaatcc ctttttatgt ttt
//
LOCUS       DARPZF010000010        65562 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.010, whole genome shotgun sequence.
ACCESSION   DARPZF010000010 DARPZF010000000
VERSION     DARPZF010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65562
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.010"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(23..391)
                     /locus_tag="SLE65_000920"
     CDS             complement(23..391)
                     /locus_tag="SLE65_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HEI8448230.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            complement(1002..2393)
                     /locus_tag="SLE65_000921"
     CDS             complement(1002..2393)
                     /locus_tag="SLE65_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HEI8448231.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            complement(2606..2992)
                     /locus_tag="SLE65_000922"
     CDS             complement(2606..2992)
                     /locus_tag="SLE65_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEI8448232.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            complement(3048..3671)
                     /locus_tag="SLE65_000923"
     CDS             complement(3048..3671)
                     /locus_tag="SLE65_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEI8448233.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            complement(3735..4403)
                     /locus_tag="SLE65_000924"
     CDS             complement(3735..4403)
                     /locus_tag="SLE65_000924"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HEI8448234.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            complement(4415..4855)
                     /locus_tag="SLE65_000925"
     CDS             complement(4415..4855)
                     /locus_tag="SLE65_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448235.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            complement(4914..5585)
                     /locus_tag="SLE65_000926"
                     /pseudo
     CDS             complement(4914..5585)
                     /locus_tag="SLE65_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5770..6168)
                     /locus_tag="SLE65_000927"
     CDS             complement(5770..6168)
                     /locus_tag="SLE65_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HEI8448236.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(6165..6938)
                     /locus_tag="SLE65_000928"
     CDS             complement(6165..6938)
                     /locus_tag="SLE65_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HEI8448237.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(6935..7618)
                     /locus_tag="SLE65_000929"
     CDS             complement(6935..7618)
                     /locus_tag="SLE65_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HEI8448238.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(7785..8672)
                     /locus_tag="SLE65_000930"
     CDS             complement(7785..8672)
                     /locus_tag="SLE65_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEI8448239.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(8669..9538)
                     /locus_tag="SLE65_000931"
     CDS             complement(8669..9538)
                     /locus_tag="SLE65_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8448240.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(9675..10961)
                     /locus_tag="SLE65_000932"
     CDS             complement(9675..10961)
                     /locus_tag="SLE65_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEI8448241.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            11234..11812
                     /locus_tag="SLE65_000933"
     CDS             11234..11812
                     /locus_tag="SLE65_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEI8448242.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            11812..12741
                     /locus_tag="SLE65_000934"
     CDS             11812..12741
                     /locus_tag="SLE65_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8448243.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            12738..14474
                     /locus_tag="SLE65_000935"
     CDS             12738..14474
                     /locus_tag="SLE65_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEI8448244.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(14537..15373)
                     /gene="pheA"
                     /locus_tag="SLE65_000936"
     CDS             complement(14537..15373)
                     /gene="pheA"
                     /locus_tag="SLE65_000936"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEI8448245.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(15370..15879)
                     /locus_tag="SLE65_000937"
     CDS             complement(15370..15879)
                     /locus_tag="SLE65_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEI8448246.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(15872..17167)
                     /gene="aroA"
                     /locus_tag="SLE65_000938"
     CDS             complement(15872..17167)
                     /gene="aroA"
                     /locus_tag="SLE65_000938"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEI8448247.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRCIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(17180..18271)
                     /locus_tag="SLE65_000939"
     CDS             complement(17180..18271)
                     /locus_tag="SLE65_000939"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEI8448248.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(18288..19454)
                     /gene="aroC"
                     /locus_tag="SLE65_000940"
     CDS             complement(18288..19454)
                     /gene="aroC"
                     /locus_tag="SLE65_000940"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEI8448249.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(19456..20520)
                     /gene="aroB"
                     /locus_tag="SLE65_000941"
     CDS             complement(19456..20520)
                     /gene="aroB"
                     /locus_tag="SLE65_000941"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEI8448250.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(20553..21575)
                     /gene="aroF"
                     /locus_tag="SLE65_000942"
     CDS             complement(20553..21575)
                     /gene="aroF"
                     /locus_tag="SLE65_000942"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEI8448251.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(22234..23208)
                     /locus_tag="SLE65_000943"
     CDS             complement(22234..23208)
                     /locus_tag="SLE65_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HEI8448252.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(23189..25072)
                     /locus_tag="SLE65_000944"
     CDS             complement(23189..25072)
                     /locus_tag="SLE65_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HEI8448253.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(25090..27315)
                     /locus_tag="SLE65_000945"
     CDS             complement(25090..27315)
                     /locus_tag="SLE65_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEI8448254.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEEKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            27430..28464
                     /locus_tag="SLE65_000946"
     CDS             27430..28464
                     /locus_tag="SLE65_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8448255.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(28531..29544)
                     /locus_tag="SLE65_000947"
     CDS             complement(28531..29544)
                     /locus_tag="SLE65_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEI8448256.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKHLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(29622..29810)
                     /locus_tag="SLE65_000948"
     CDS             complement(29622..29810)
                     /locus_tag="SLE65_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HEI8448257.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(30250..30378)
                     /locus_tag="SLE65_000949"
     CDS             complement(30250..30378)
                     /locus_tag="SLE65_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEI8448258.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(30381..31754)
                     /gene="rlmD"
                     /locus_tag="SLE65_000950"
     CDS             complement(30381..31754)
                     /gene="rlmD"
                     /locus_tag="SLE65_000950"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEI8448259.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(31865..32920)
                     /locus_tag="SLE65_000951"
     CDS             complement(31865..32920)
                     /locus_tag="SLE65_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEI8448260.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(32930..34360)
                     /gene="gatB"
                     /locus_tag="SLE65_000952"
     CDS             complement(32930..34360)
                     /gene="gatB"
                     /locus_tag="SLE65_000952"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEI8448261.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(34357..35829)
                     /gene="gatA"
                     /locus_tag="SLE65_000953"
     CDS             complement(34357..35829)
                     /gene="gatA"
                     /locus_tag="SLE65_000953"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEI8448262.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLAHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(35829..36134)
                     /gene="gatC"
                     /locus_tag="SLE65_000954"
     CDS             complement(35829..36134)
                     /gene="gatC"
                     /locus_tag="SLE65_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEI8448263.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(36240..38276)
                     /gene="ligA"
                     /locus_tag="SLE65_000955"
     CDS             complement(36240..38276)
                     /gene="ligA"
                     /locus_tag="SLE65_000955"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEI8448264.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(38293..40527)
                     /gene="pcrA"
                     /locus_tag="SLE65_000956"
     CDS             complement(38293..40527)
                     /gene="pcrA"
                     /locus_tag="SLE65_000956"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEI8448265.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            40682..42241
                     /locus_tag="SLE65_000957"
     CDS             40682..42241
                     /locus_tag="SLE65_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEI8448266.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVVGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(42352..44283)
                     /locus_tag="SLE65_000958"
     CDS             complement(42352..44283)
                     /locus_tag="SLE65_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEI8448267.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(44301..45215)
                     /gene="pfkB"
                     /locus_tag="SLE65_000959"
     CDS             complement(44301..45215)
                     /gene="pfkB"
                     /locus_tag="SLE65_000959"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEI8448268.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(45212..45964)
                     /locus_tag="SLE65_000960"
     CDS             complement(45212..45964)
                     /locus_tag="SLE65_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEI8448269.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(46123..46332)
                     /locus_tag="SLE65_000961"
     CDS             complement(46123..46332)
                     /locus_tag="SLE65_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448270.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(46343..47671)
                     /locus_tag="SLE65_000962"
     CDS             complement(46343..47671)
                     /locus_tag="SLE65_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448271.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            47807..47962
                     /locus_tag="SLE65_000963"
     CDS             47807..47962
                     /locus_tag="SLE65_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448272.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(48036..48623)
                     /locus_tag="SLE65_000964"
     CDS             complement(48036..48623)
                     /locus_tag="SLE65_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEI8448273.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(48706..49956)
                     /gene="clpX"
                     /locus_tag="SLE65_000965"
     CDS             complement(48706..49956)
                     /gene="clpX"
                     /locus_tag="SLE65_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEI8448274.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(50203..51492)
                     /locus_tag="SLE65_000966"
     CDS             complement(50203..51492)
                     /locus_tag="SLE65_000966"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEI8448275.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(51646..52578)
                     /locus_tag="SLE65_000967"
     CDS             complement(51646..52578)
                     /locus_tag="SLE65_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448276.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(52735..53394)
                     /locus_tag="SLE65_000968"
     CDS             complement(52735..53394)
                     /locus_tag="SLE65_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HEI8448277.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(53397..54422)
                     /gene="sppA"
                     /locus_tag="SLE65_000969"
     CDS             complement(53397..54422)
                     /gene="sppA"
                     /locus_tag="SLE65_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HEI8448278.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(54435..54725)
                     /locus_tag="SLE65_000970"
     CDS             complement(54435..54725)
                     /locus_tag="SLE65_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448279.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            55134..56939
                     /gene="glmS"
                     /locus_tag="SLE65_000971"
     CDS             55134..56939
                     /gene="glmS"
                     /locus_tag="SLE65_000971"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEI8448280.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(57011..58366)
                     /locus_tag="SLE65_000972"
     CDS             complement(57011..58366)
                     /locus_tag="SLE65_000972"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEI8448281.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(58390..59559)
                     /locus_tag="SLE65_000973"
     CDS             complement(58390..59559)
                     /locus_tag="SLE65_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448282.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(59556..60443)
                     /locus_tag="SLE65_000974"
     CDS             complement(59556..60443)
                     /locus_tag="SLE65_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEI8448283.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(60632..64324)
                     /gene="nifJ"
                     /locus_tag="SLE65_000975"
     CDS             complement(60632..64324)
                     /gene="nifJ"
                     /locus_tag="SLE65_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HEI8448284.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            64523..65044
                     /locus_tag="SLE65_000976"
     CDS             64523..65044
                     /locus_tag="SLE65_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HEI8448285.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
BASE COUNT        18252 a        14202 c        11672 g        21436 t
ORIGIN      
        1 aaaaacaaag tctttatttc tattatttac ctgtaaccgc aaagtagttg ccatcgggat
       61 cagcaaagtt aaagacatat tcttctccaa gctgtaccat atcacctaat gtgactgatt
      121 gcgtctgcat ttttttatat agtccaaaga tatctttact gtaaaacatc aaagatgggg
      181 cactagtagc tgtgccaggt gaatgggact caacaaatgc tcgatcatat aacagaaatg
      241 aggtttgact gtcctcaact cctacttcaa ttataagcgt cccatccatt tcttgacgat
      301 ctttttccgc aaagccaact gctctccaaa acgttgcatt tttttctaca tcgtccacat
      361 aaagcatgat ttttatttca ttcgtaaaca tctgtttcct cctaaacgat ctgttctaac
      421 attctcaact ttgtcagttt accataggaa aatgggaaaa tctacgaaag ctctcaacag
      481 aatcgtccta cttaaatacg cttttcttta ataataaata agttggttgt ttttgttatt
      541 tgcgctttca cttttcggaa taaataatgt gtatttatat ggaataaata aaaaaagagg
      601 tcgtgactaa aaacaagtca caacctctgg taaacggtgt tctcctgaca actcctcggt
      661 cacaagacac aatattcaac aaacatgaga agctattttt tgaaattgct ctttgtgact
      721 cagagtgaaa cggcaggctc acgacctctt tcttaaacgg tgttcaaaag cttgcatctg
      781 cggtaataag ctcaaccaaa cgtaaaatat gaggaactat ttttgtttgg ctgttcttat
      841 tacttgatgc agggcagctt tttcacaacc tcttattcac ggtgtttcag aagtagcttc
      901 tcggaaataa gccgaaattt cacaaaaatt tgagaaacta tttttaggaa acttcttctt
      961 atttcttaaa gctgaccact tctatcacaa cctctttttg actatgcatt cacatcgatc
     1021 actttagaat catcattgat gacatcgcga tctaaatctt tgatgcgtgc acttgtcacg
     1081 ataccagcta ccatgctacc gctgacgttt actgctgtac gtgccatatc gattaatggt
     1141 tcaacagaga taactaaccc aacgattgct actggcaagt tcattgcccc taaaacgatc
     1201 agtgaagcaa atgttgcgcc cccaccgact ccagctacac caaaagaact gattgttaca
     1261 attgccacaa gcatcaaaat aaattccaaa ctaaagacat tcactccagc tgctggtgcg
     1321 acgatcgttg ccaacatagc tggataaacg ccagcacagc cgttttgtcc aatagacaaa
     1381 ccaaaacttg ctgagaaatt agctgttgca tcatctactc ctaaagcttt tgtctgagtc
     1441 tcgatattca atggcaaagc tccagcactt gaacgtgaag taaacgcaaa gctcaatacc
     1501 ggaaaggctt ttttgaaata gttgattgga ttgacttttg caccaatcaa aatcagtgag
     1561 tggacaatca aaacagcaag caatgctacg taagaagcaa cgacaaattt acctaaattg
     1621 acgatagctg caaaatcact tgttgccaaa acgtttgtca tcaaagcaaa tactccataa
     1681 ggtgtcaaac gcaaaacaag cgtcacgatc cgcataatga ttttatacag actgtcgact
     1741 aaatctgaaa agaatgctgc ttcttttggc gcttttcttt tcacgcctag ataagcgatt
     1801 ccgacaaatg ccgcgaaaat aacgactcca atcgtacttg ttgcacgact acctgctaaa
     1861 tcagcaaaaa cgtttttagg gataaaggat aaaatctgct gtggaatcga taagttttca
     1921 actgtttcct gacgtgttgc cagttcagag attcgtgctg tttctgcagc tccttgtgtg
     1981 aatttagctc cttggagtcc gaacagcatt gttgaaccaa ttccgatcaa tgctgcaata
     2041 gctgttgttc caagtaaaga agtcaataca gtcgcactaa ttttccctag cttttcagaa
     2101 actttcattt ttgtgaatgc accaatgatc gaaataaaca ctaaaggcat aactagcatt
     2161 tgcaagaatg atacatatcc ttgacctaca atcccgatcc attccattga ttgagtaacg
     2221 actttgtcgt ctacaccaaa gatcaattga agcagaccgc caaagacgat accaactcct
     2281 aatgctgtaa agacgcgtgt tgaaaatttt gtatggcgct tttgcatacg atagaacaca
     2341 tataataatg ccgcaaaaac tagaaccact aaaactgtga tgagtgttgt catttttctc
     2401 ctcctcatat tattaatgac aagtccatcg aaggaagtaa aggttcccga gaatgattct
     2461 tcaaccatcc tcctgaaaaa atttttttca gtgactttta tattttagac gatttttatc
     2521 gaaatgacat tctttttgct tacaattagt aataaaaaaa catacctgtg atagctttaa
     2581 tctatcgcag gtatgttttt actgtctatt cttgtttttc tgattgaaaa ttcaatttta
     2641 ccccaggctg atctaaggcg atctctgtca cctcataaga cattcggcgt acgatatcga
     2701 ataacggtgc tactagctcg tccacttctt cttgtgtgac atcattttga ccttcaattt
     2761 tccgattgag gatatgattg atctgactca cacttccaga taaaacatat gtatcaaaca
     2821 ctaaacggaa ctctaagcgt gctcctacga tgctatgttc tttcggatag ttttcgatcg
     2881 tttcttttaa aggcgagaag cctactttca aatctgtttc tacttcttgg ttcggcaatc
     2941 tcatatcata atgaaatgct tctacaactt ctttttgtct tctgatttcc atataatttt
     3001 atcactcctt tatgaaaatt ataacatatc tcctttgaaa ggggatacta ctttttaatg
     3061 atgctctgca aggtaaggat ttcattcaga tttcctacca cataatctgc cgggatctca
     3121 cccagaaaat gatcgatgtc gtaaagacaa gtagcgactc ctgcattttt ccctgcttcg
     3181 atatctaaac gacgatcgcc gatcatcatc gtgtctgttc tttctaaatg aaaagtatcg
     3241 atcaaataat ttaaagatgc tggatcaggt ttacgaggaa agtcctgatc gatccctact
     3301 acttcctcaa tcagatgtgc caatcgatgt tcttttaaca ggccccatgt tgattctgtc
     3361 aaacggtggg tcaggatgaa atgacgaccg ccgttgtctt ttagcatttc cagtacttgt
     3421 ttcgtttctg gaaatggacg ggaaacttcc gtactttctt tttcatatcg gtgaaataat
     3481 tcattaaact ctctggcatt caagtttgat tcattgatca aataactagt agaatacttt
     3541 ttcattttga agtagatttc ttttttgtcc atactgatac caaaatcttt tagtgcttgc
     3601 catgcaccat ctaccattgc gggatacgta tcaaacaatg taccatcaaa gtcccatata
     3661 taatttttca tgttcctttt gttccattcc tttgcttctt ttttctatct ctcactttta
     3721 gataaaggtg ttctttaaag tatttttttg tccagaattg tcaaatcatc tgctaatgta
     3781 tactggattg gttgtgcatt tgggatatcg atcgtatcca tttgatcttc aggaacatct
     3841 tctaaatatt ttgtcagtgc tcggatgcta ttaccatgac ccacaactag taaatcttgc
     3901 cgatctttta gttttggtgc tagatgatct tgccataagg gaatgatccg attcactgtc
     3961 atttccagac tttctccgta tgggatcaaa tgcggatcca agtgatcata tctgcggtca
     4021 aatctatttt ctgcggttaa cggcggaact tccgtatatc ctctgcgcca tgtttttact
     4081 tgatcttttc cgtatatttc tttcatctta tctttgtttt tacccacaag atccccataa
     4141 tgccgttcat ttagacgcca tgtttttatt ataggaagcc ataactgacc catttcttct
     4201 agtgcgactt gtccggtaag aatcgcacgt ttcaaaacag aggtataaac ggcatcgaat
     4261 tgaagtccgg cttcaagcat tttttgaccg gcaactgctg cttgttcttt tcctttttct
     4321 gttaaggcga catctagcca tcctgtccag taattttcaa aatttgcttc gctttcgcca
     4381 tgacgtaata atactaattt cattcttttc tcccttaaac attcgtttcg aattttatac
     4441 cacatgtttt gcatgtcaca cgtattcgtc cttttccttt aggtgcacgc tgcttttgat
     4501 gacaattcgg gcactcaaaa aaagtataac tttttcgatc cattttgact tgctttttgt
     4561 tttttatctg atgatatttt tctttgactc tatcaagata tttcaaataa cgttgattct
     4621 catttagtct ggggtagatt ttttttgata ggaaacgaaa tatcatccat ccgaaaaaga
     4681 cgatgaacaa caattgtccg attctatagg gcaaccaacg acttagcaaa ctaaagacaa
     4741 gcgcagcgat caatagaccg cgattcaact gatcaaattt cgcatatctt ccctgcataa
     4801 gtttgtgata gttctgctga aatcgtatta gcctttctaa ccatgtttgc atcatattat
     4861 ctcctccatc atctaatatt tattatgaca aaaaaatcca aaaagaaaaa gccttaattg
     4921 gccttttcca ttgcaacttg gtgaaggaca ttccgatttc tggtaaagtc aatcacaatc
     4981 actttctttt tatcttctct gttgactact cgaaatgtgt ccgtcaatgg aagaaacagc
     5041 ttcttagatg gtagctgttg catacgtata aaacgatgga tcatcgtaat caattgagga
     5101 aattgaatag acgtgtgaag cagacctgga tattttttca acagctgtgt cgttttgatc
     5161 agattccgtt ttttactgat cactttttaa aagcttttta gaatcttttg ctgacgtcta
     5221 aaaatagaaa aagaattttc gtcatctatt tgataacgca tttgtttttg cagttctgct
     5281 gcagtcagat ggatcttccc atcgtttgta tcgatcatta aaccttctgg aaacagttca
     5341 accactgctc gatcccaaga ttcaagagaa agctcgatat aatcttttac tggtaattcc
     5401 aattctacct taaaaaagtg caaaacagcc gacagccctt ctgcttgata gatttctcct
     5461 aatgttagcc cctctagatg gaactctggt gaaaaatgca gcaatgtttt attttcctgc
     5521 aattgaacat atagaaatgt agatcgctca atcagagtat cttttaaaac aactaaaaaa
     5581 ttcatttttc tccccctttt ttcatcattt ttaaaatagc atattttgaa aagaaagtct
     5641 gatgcttaga gtagaatttc ataaaaattt actatttcat aagtattcac gagaaaaata
     5701 caaacaaaaa agcggaaata acgctcatcc gccttcttgt ttgtgtttat ttcctcttca
     5761 aacgcttgtc tatgattcag acttttctct atcgttattt tcatctaaaa gttcttgcat
     5821 tccgataatt tctcgatatt gatgaatctt agtgatacca atgactttgt ctacatcaat
     5881 actaaaacaa ataccattac ctggaatatc gatgttgatg ccttgaccaa tcgcatccat
     5941 tactttattc gtcaaactat cgggtactaa tgtcaacaca atatcttttt ctggcgaaat
     6001 gtccaaacct aaaaatttcc ctgaatcatg tacaccagaa cctcttccat gtaagatcgt
     6061 tccgcctgct gcacctgctt cttttgaaaa gtcgataaca tcttcgccca ttcctccgtc
     6121 aacgatcgtc acaatcatgt gaagattcaa tgctacaaga tctttcattt gctttccccc
     6181 aatttttgca atctttcttt ttcgattctg tctttttcat cttttcgttt ataaatatat
     6241 cctagtacta aagtggataa tattggtgtc aatgcaatca ttgcaaccac accaaacccg
     6301 tcaatgatcg gatctcttcc ttcaatttgt gcagcgattg ccacgctcat tgataaaata
     6361 aatgtcgaac acatcgggcc cgttgctact ccaccgttat caaaagccat tgctaaaaag
     6421 atcttgtcca cttttcgtcc taaaataaat gctagcccgt atcctgggat caagaaataa
     6481 taaagagaga atccgacgag caaacgccac atagacaatc ctactgctgc gccgatccca
     6541 attgaaatta ccatcagcat gattttcgat cggattctcc cctcgctcaa ttcttcaacc
     6601 tgtttgatca ttacatgaat cgccggctca gcaaacccta ctaagaaccc cattaaaaag
     6661 ccaaggggaa ccagtatata attgtaaggc aatcccgcaa tagcactgcc taaatgctgt
     6721 cctaccggta cataagccat attgactccg tgcaggaaaa ggatcaaccc aatagtcgtt
     6781 atcaagaaac ctttcataat gtcaaagaaa cgctttttgc gcatacgaaa actaatgata
     6841 ttcattaaaa caaataggat tacgataggt gccactgcca aaatgacttc catggtaacg
     6901 atttcgattc catctatcac ttgctgccag aaactcattg gaagatcacc cccaaaatca
     6961 tcacggcaag aatcggccct aacgaagcaa taccgaccat tccaaaactg tcattttcat
     7021 ttttcttttg tttgatcata ctagtcatcc ctccggcaag ggccaagata aatggaacag
     7081 ttactggacc agtagtcact ccccccgaat caaaagcaat cggcataaat tcggaactgg
     7141 tgaaaaatga ggcgatcaaa acgcctatgt agcctatagc catcaattga taataggata
     7201 gcttgaatac gacccgaagc agcgcaaagg ctagaaatac tccagtgccg acgctgacga
     7261 tcccaatcag caacactctg ccaatctctc cgtcagatat atcatatact tgttgtccca
     7321 aaacttgcac ggaaggttca gcaatcgtga tcacgatccc gatagcaaat cccaaactga
     7381 ccaaaacggt caaacttttc tttttgatca tatatttccc tactagatct ccgacttcca
     7441 tcatagaata atctgctcca aacaaaaaga gcgtcattcc gatcatcatg attgccgcac
     7501 caaccagaaa tgaagcgagg tcttctcctt ctaacggtgc aaaaacaaac gttaaaatga
     7561 caatcaggac agtcatcggc aatatagcag caatcacttc tttaaaattt tttagcatgt
     7621 atcctcctcc tttactcttt aagtttacct taaaatgaaa gagttttcga gcacaaactt
     7681 aaaacgttat catttaattt ttctcaacat aaaataacac acgtcccaaa agtatctttt
     7741 tacttggaaa aatgactttg aaggaacgcg cttattgtgt ttttttattt tacagagccg
     7801 atcattcctt gaacgaattg cttttgcaaa acaaaaaata cgatggcagt tggtaaagta
     7861 gcgatgacta atccagccat gatcattcca tagtctggtg tataggaagc acccatagca
     7921 gataaaacaa gcggaaccgt ccgtttatca ggagattgca aagctactaa gggccataaa
     7981 taattgttcc agctactcat gaatgtgatg attgcagccg cggcataggt atttttagcc
     8041 gtcggcatat acactctaaa aaaaatactt agttctttta gaccgtctaa tcgagcggct
     8101 tctactagat cttttggaaa agatttaaca ttttgtcgaa agaagaagat caaaaaagca
     8161 gtgctaacag atggcaggat gacaaccaag aaactgttga ttcccaaaac cgttccgttc
     8221 aattgtgaaa acattcgata taaagggatc atcaatgccg caaaaggaac catcatcgat
     8281 agcagtagaa tattgaaaat taggtctttt cgtttacttt gataaatctc aaatccatat
     8341 cctgccattg acgaaatcag caatgcaaac acagtggtca ccaaagcgat catcgctgaa
     8401 ttccaaaggg aacgagtaaa attcagctca ttggaaaaca aattttgaaa attgatgatc
     8461 aagttactgc caatctttat ttttcccgat gtgatatcca cgggtgtatt cgtcattccc
     8521 aaaaccatcc agacaaaagg gaaaatggaa ataaatgata ggatgcttaa tgctgtatac
     8581 tttaatactg acccaattgt cgaacgaagt tctaatgctt gttttttgac gttggggcgt
     8641 tcgattgttt ctttttctac catatttttc atcgactttc tcctcctact ttcgtttgga
     8701 ttatcgacaa tatcacaata aaggaaacaa taacaaagga aactgctgcc gcatatccaa
     8761 aattaggcgt gaatttataa ctcaaattat agatgtattg agatagggtg gtcgttgcat
     8821 ttgctggtcc cccgccagta atattttgta cttcatcaaa aagctgcaat gtcccgatcg
     8881 tcgaagtaat ggaagtaaac aaaatgattg gttttaaatt tgggatcgtc actttgataa
     8941 actgctgcca tttagaagca ccgtcaatag atgctgcttc ataaatctcc gaatcaatat
     9001 tttgcatgcc tgaaaggaaa aaaatcatat tgtatccagt ccaacgccaa gtgatcgaaa
     9061 gaatgatcag aactctcgcc caaattggat gagtcaacca gccaatcggt gtgtcaatca
     9121 taccaatgcc caacaacaag ttgtttacaa ggccagattg agaaaataga cttttcatga
     9181 tcagagaata actgaccatc gaagtgatac atggaagaaa gatagcggtt cgaaacaacc
     9241 ctttatattt caacttttta tcatttaaaa ggttggaaat aaaaagtgct agaaacaaca
     9301 tgatcggtac ttgtacaagt aaatacagga atgtattaaa aaaagctttt ttaaaagttg
     9361 catctgtcaa catccgctga taattaccta acccgttaaa tgtcatattg acagggggac
     9421 cactttgaaa agacgtgatc aaagccaaaa ccatcggaat aaaaaccatg attgatatca
     9481 aaatgactgg caagattaaa aaagcatgcc cgtttttgaa taaatctttc tgcttcattc
     9541 ttttccctcc aattctatca ttgattatct acatgaaaag acaagaaaga caatatctgt
     9601 aaggcagacg tgatcttttt tgtcttttcg tttgtctgat gaaaaagcga agaaattcac
     9661 ttttttacca ccgatcaatt agccaattgt gcttctactt gtttttgtgt atctgctagt
     9721 accttgtctg tctcttctcc attgatgatt cgatgaagag cttcagctac gactgcttca
     9781 attgcatagg tctcatgtcc gtaattcact tctggtattt cagatgtcca tgttgaaaaa
     9841 tcgtcaaaga tcttttgacc actgtaaaat tcagaagctt cttgataagc ttcttgttca
     9901 ttcgcgctaa gcatcgtaga tactagtccg atttctttcg caagagtgcc catcagttct
     9961 tcattcgaag caaacgttgc ttctaggaaa tctttcgctg aatcttctcc agctactcct
    10021 ttgatcacat accagccagc gccgccaagg ttagaagctt gcgctttttg cagattttct
    10081 ggaagtgcag gtattggtgc aatcttccat tttccagatt ggttttctgc tccttggatc
    10141 gttgaagaat accaagcgcc agttgggcta gaagctactg ctcctgattg tatcgcagtt
    10201 actccagcat tccagtcaga ggtttgttcg actagatctt ctttcaaaag agtggcaaac
    10261 aattcaagac catactttaa agatgcattg tcttggatcg tgactgtctc cccatcttca
    10321 gatgtatacc attctcctgc ctgttgcata atcatcctta ctcgaccaag gtcagaagga
    10381 ttgacttcag cgattttctt tcccgtcttt tctttgacat ctcgcgctac ttgaatatac
    10441 tcgtcccact tcagattctc catatcctct tctgtataac ctgcttctgc catcagatcc
    10501 gtacgataga agtttgctgt tacgcccgaa tcgaaaggaa caccgtatat tttatctcct
    10561 actttgttta ccgcaaattt atacggtgca aaatgatctt cctttacaat agcagacaaa
    10621 ttagcgaatg catctggata agaagtcaaa tagccttgta tcctataatc ttcaatcaag
    10681 acgatattgg gcaatccttc tgtattcccg ctcgctaaag cggtgttcag tttctgaacg
    10741 atatcatcct gagacatcgt aacaacttct atctctgttt cttcgttctc ataaactttt
    10801 tttgcttcat tcactgcttt gatattgaat gtctcatccc acgcccagac agtgactttt
    10861 tcttctttgt ctgctgtact actagcactt ccgcatcctg ttaagaaacc tgatgctgcc
    10921 gctaaacaaa cgactccagc aattaacttt ctgatgttca tttttatccg ctccttttcc
    10981 atccattagt tgtttacgtt tgctacattc atcataccaa aatttgaaaa cggtttcttt
    11041 attattcaga tacttcaaaa atttctccta aaataataaa aaaatacaaa tcaactatga
    11101 caaaaggaat aatcttagca tctagaccaa agatcgaaat ggtgaggttt ctttaaaata
    11161 aaaatatcct tgcattttct cctagaaata agtattttta aattacaaga ctattcttaa
    11221 ggcgggtaaa aaaatgccaa tacgcgtaat tcttatcgat gatgaacaga cgattttaga
    11281 tggaatgaaa cagttgatca attggtctga gcacgggttt caattaatag ggactttttc
    11341 cagtccgctg aaagcgcttg atttttcttt ggtacatgca atcgatatcg tggtcacaga
    11401 tgtaatgatg cctgaattaa atggaatcga attatcgcgg ctattaaaac agcaacaacc
    11461 tgaaacacag atccttatcc tctctagcta tgatgaattt gatatggtta aagattcttt
    11521 taaagaaggc gtcgctgatt atcttttaaa gcctcgattg agtcctgatt tttttctaaa
    11581 ttccttaact gccgtttcac aaaaaatcaa aaaaaagccc aacaaaagcc caatcaccaa
    11641 tcgttatgag cagatctgcg agaatctttc acagcagatt gctggacaaa ctcgtccatt
    11701 gcttgaccct cttctttttg aacacacctt gtttttctgt tatataccga aaaacggcca
    11761 ttcagttcaa aacaaggctc taaacaaaaa cagtcgatca cccattcatt gatggatagc
    11821 gacgattcgt ttactattta tcctgtttct accttttcgg aagaatccgg ctatgtaatc
    11881 aatactgatt ccaaagatac acttaggaag tttgttcaaa agtttcgtca agaagttttt
    11941 ccaggtgatt tttttgttgt ttctgattct tttgcaatcc aagatatcaa tgaaatattc
    12001 caagagatca gaaattgcac caaaggacaa cgtttctatc ataagggaaa gaaccttgct
    12061 tatcagcatg aacttcttcc gttattaacc aaccacgagc agcaagcaag tagttattta
    12121 acaaaaatcg ttcataaaga ctacgcttta gctgtcaaag aacttgagaa tttcttcacg
    12181 acgatattgg aacagcctat tgatccagct tatttgaaac atgaggcaat caatcgtttc
    12241 tatgcattac tcaacgcttt ggctgacgag catgttggga atgaagaact ttctttgctc
    12301 aagatcgccc ttccttcttt attagccgat gctgagtatt tcgaagattt ttctattctt
    12361 gtcaaagaaa cacttgagaa actcacccac ttttctgcaa atgcaaaaaa agacaatttc
    12421 gatatcttga ctttgatcta cgagttcgtc caggaaaatt atgagaaaga aatcaattta
    12481 caacttttat ccgaaaaata tcatttttca tatagctatc tctcagccat ctttactgaa
    12541 aaatttggta tcaacttttc aaaatatcta aaaaaagtcc gtatcagtaa agccaagctc
    12601 tttttgacgg aaacacggct tactttgacg gaaatctgtg agaaagtcgg ctataccgaa
    12661 ctgggttatt tctccagagt ttttaaagaa gagacaggaa tgacaccttc tcaataccgt
    12721 aaaggaactt ttgtaaaatg agaaaaaaaa tcaaagagca tgaactcttt gccaaacttc
    12781 tgttcatttt gttcatcggt ctttttctgc aagccatcgt catttctttg tttatttatc
    12841 atcgatcaag ggatgcctat atccagctgt tcaatcaatc gaatgatgtg gtactaaaaa
    12901 agattcaatc tgaatttgaa agtttgaatg atacaatcga gaatacatta gccgcttttg
    12961 attctaatcc agctgtcaaa agctattttt ccaatgatcc agcccaacat atggaacagc
    13021 ttcagcaact aagaacaatc caaaaaatga atgactctct ttcaaaaatc catccaatga
    13081 tcgattacga tgtattgatc tttggagaaa atggaagaac ttttgtcgga aacgacatgc
    13141 tcactgccgt atctgccgat tctttttttc aatctgcgat tgctcagaga gtgaatgaac
    13201 gtgctgctga tacacaaatg ctttttgcac accacggatt gactcttcgc gataagaaag
    13261 cacccagcgt cttctttgtc aaaaaactga aaaatacatt gaatcacgtt tacggatatg
    13321 ctgttttatc gatctcatcc aagcaactag cgaatctttt tcaatctgta gtaaatcctg
    13381 agatatcgaa gatctccttc atgaacgaag aacagacgat catcgcatca aatgaagaaa
    13441 atacaattgg gagccgatca atgattttca aaaaactaac agtaggtgaa acaacgattt
    13501 caaatggaca gcagttgacc cgtcttcctc tgtaccgcca ggattgtaca ttactcagtc
    13561 aagtcgatct tcattcttta tctaaccaaa tgggcgtgat ttttccgatt attttgtata
    13621 atatcgtgac acttgctttt gctggctcat tggtatttat gtatttggat cgacacacaa
    13681 aatcgatcta ccgcttgatt gattcgctaa aacggctaga ggaagatggc ttaaaagcta
    13741 ctgttcctgt acaaggaagc catgaagtcc aattgctagg gaatacgatc aatcaattgc
    13801 taagtaatgc tcagcatcat tatgaacaga cgatccaaga cgaaaagaag aaacgttcgc
    13861 ttgaaatcca aactatgcaa gcacagatac agccccattt tatttataat acgctgacta
    13921 gcttgaaatt tttgatttgg cagaaaaaaa cagatgaagc agttcaagga atcgacagtt
    13981 tcattacttt actaagaagt acgattggga aaaaagaaga agtgattcca gtcaaggaag
    14041 aaatcaaaag cgtacaaagt tacatcgatc ttttgagtat gcgatatggc gaaagaatct
    14101 cggctaaaat aatgattcct gatgaactgc agtcattatc tatgccgaat atgatccttc
    14161 aaccaattat cgaaaacgcc tatcttcatg cttttcacaa taaaacgcaa ggattcatca
    14221 cggtgtacgg caaaacaaaa aatcagcttc ttttattcga agtgattgat aacggcgatg
    14281 gcttcgatac tgaaaatacc aaacaaaaaa atgatcattt ttcaggaatc ggcatcagcc
    14341 atgtagatga gcggatacgc ctaatgtatg gcgatgcata tggcttaacg atccaatcag
    14401 tgattgggac aggaacgact gtaacgattt gtctaccgct tcttcctaaa aatcaatcag
    14461 aatatcaaaa ataaagaata gccaagcgct gattttttta ttttaagtta aataaatcaa
    14521 tcagtattct tgactttcat ctacgcgtct cttctactgt cagcactgga taacagccca
    14581 atatttgact ttctcctccg agcatcttga tttcttggag cgcattctct actaatgtca
    14641 ttggacggtc caacaacaaa tcgatcacga aaaaatattc tcccaagcta gttttcaatg
    14701 gtcgggattc aatcttactt aagttgattt cccgccagcc aaaagctgcc agcattttat
    14761 gaagcatccc tggccgatta gcaggtagtg tcaagatgac actcattttt actggagctg
    14821 actgctggct ggtcatcttt cggtcaccga cgatccaaaa acgtgtctgg ttcaactcat
    14881 tatcttggat attctcagct aagatctcca atccaacatg ctgtgctgtt tctaatgaag
    14941 caatcgctgc tgcgtcttct ttcggatgtt ctgctacata cattgctgca gcagttgttg
    15001 attctgttgc tactaaagga acattaggat aatgcgtttc taaaaactgt tgtgattgtg
    15061 ctagtgcttg tggatgtgaa aggatttttg taatctttgt tgctggattg cctaaaagct
    15121 gctgcttgat aggaagaacg atttcacttt taacttcgac ttctggatgt ttggaaagaa
    15181 gatcgattgt gtgatgaaca gctccttcca atgaattctc tacaggaacg acagccagat
    15241 cgacttgttt gcgaaacaaa gcgcgcaaac aaacagggat ggaagcatac gcagtcaatt
    15301 gttctgtagg aaatagctga caagccgcct gataagtgaa tgaactttct ggccctagat
    15361 agctgacgtt catatgcttt tgatcctttc tataatggta tcgatgatct tttctggtgt
    15421 ttgattggtc gtgttgattc gatgtgtcgc actttcttca taccaagaaa gtcgttgtgc
    15481 caataatgct tttatttctt ctcttgtttt tccaagagct aaaggtcgaa tagacgtttc
    15541 atcttgttgg atacgatcaa ctagacagtc cgcttctgcc tctaagtaaa gaacaatcgg
    15601 ctgtgttttt aaaaaacgcc gattttctgc actttggaca atccctccac cagtcgcgat
    15661 aattttgtct tcatttgaca gctttcttaa aatatctgac tccacttttc gaaagctttt
    15721 ttcaccgtaa tagtgaaaat attcggcaat cgacaattgg atatgttcct caatctttgt
    15781 atctaaatct acatactctt tttgtaaaca ttgagctaac cctttaccga ttgttgtttt
    15841 tccagcgccc atgaaaccaa tcagcaaaat gctagccatg agcttctcct cctgacacaa
    15901 gttctgctaa atcgtcaaaa aatgccggat aagagattga aacagcttca gctccttcta
    15961 gttcgcaagg tccatcagct atcaaagcag ctacttgcag catcataccg attcgatgat
    16021 cgcctctgct ggacactttt gcgccatgca gaggtgtcgg cccatggatg atcagaccgt
    16081 ctgctgtcgc ttttatcttt gctcccattt tctgtaattc ttctgccacc gcatcaattc
    16141 tgttggtttc ttttactttt aattcttctg cgtctttgat gatcgtgatt ccttctgctt
    16201 gagtagccac taaagctaga atgggcaatt catcaatcag acgcggaatg atttctccac
    16261 caatcgttgc tttcttcaaa tgactcgtct tgacacttaa atcagccgat tggttctgtt
    16321 cattgtgatt cgtctgggta atcgctgcgc ccatctcctc caacacatct aagataccag
    16381 ttcttgttgg attgaccccg acatttttta acaacagttg gctttccgga acaagaagtc
    16441 ctgctgctag aaagaaagca gctgatgaaa tatcacctgg aacagttatc tgttgaccag
    16501 ttaatttttg cggtccggtc actatgatcg ttttatcttc cactgtgatc cttccgccaa
    16561 attgacgaat catttcttcc gtatggttac gggaacgttc tttttcaacg attacggatg
    16621 tgccttctgc ttgtaatgcc gcaaacagca aagcagattt gacttgcgca ctggctacag
    16681 gcatattgta tcggataggt gataaagagc gggttcctgt cacagtgatt ggtagatact
    16741 ggtcattttc ttctccttgc aagtcagcgc ccatctcgcg taaaggttcc atcactcgcc
    16801 ccattggacg tttagacaac gaagcatccc cgaacagagt agtcgtaaaa ggctgtccag
    16861 ccaaaatacc catcaataaa cgtatggtcg taccggagtt tcccatgtca attgattcgg
    16921 ttggttggac aaatgagtgg ctaccgcgac catgaatctt gatcacctct tcctcttctt
    16981 cgatctcgac acctaattgt tggaaggcat gtaaagtact cagacaatct tctgcgcgca
    17041 aaaaattttg tatagtcgtc gttccttcag caattgctcc aaacatgatg cagcgatggg
    17101 aaattgattt atctgctggt atcctaacag tccctcttaa tccatgtatt tgttgtaata
    17161 attgcattta tccagcctcc tatttgatcc agcaatgata actggtatta gacataatga
    17221 ttctttttgc ttgtaacaaa tcctgttggt ttttaaaact gatttgcagt attcctaaaa
    17281 tatcttccct ggtctcttgg atcttcaaat taatcaaaga aactcccgct tttccgatca
    17341 gtccagttac ttctgcaata acgccaggtt catctggcac atcgataaat aaatcaaaaa
    17401 aggcaggaat cgcgccttgc ttatggacag gcaactggtc tcgactttct tttgcccgat
    17461 tgaaaaaaga aaagatttcc gattggttct cagtcatgat ccattctgct atttgtgtca
    17521 tttcttgttg ccaatctgcc aatcgttcca ataatatctg cttattgctc aacaaaatat
    17581 ctgtccacat gacaggatct gaggaagcga tcctagtgat atctcgaaag cctcctgctg
    17641 ccagttgttt ggctcgcgga tactcttgat tgaattgttc tgcctgattg actaagccag
    17701 ctgccagaat atgtggaaaa tgacttagca ttcctgttat acggtcatgt tctcttgctg
    17761 taagagttac atattttgct ttggttccgc aaaatagttc ttgcagtttt tcaacatctt
    17821 ttttcgtctt ttccaaaggt gtaaagatgt aataggcatt ttcaaatagt ttagcatctg
    17881 ctgcctgtat acctgattta tgagaaccag ccattggatg tccaccgaca aaccgaagat
    17941 ttttctgctc agcggatgtc acgacttgct gcttcgtact gctgacatcc gtaatgatga
    18001 cgtgatcaga caagttgatt ctttcaagga catcaagata agctaaggtt gtacggacgg
    18061 gaacggctaa taagataacg tctgcttgtt ctgcacctgt ttcaaaatca cttgcaacgt
    18121 aatcaacgat ctgctgttct actgcttgct cacgggtttt tgactgacta tcccaaccaa
    18181 ctactatcag ttctggattg gtctgacgaa tacaaagtgc catagaagca ccaatcagtc
    18241 caagccccac gataaaaaca tgttgtgcca tcttatttgc ccccttttta gtaatgtttc
    18301 aagtagtcac ggtactcctt cactgcagct ttcaactcaa caagcgaatc acttgggaat
    18361 tttgacaata gctctgtcgc taccacagtg gctacaacat tttccgcaac gacgctagct
    18421 gcaggaactg ctgtactatc cgaacgttct acacttgctt tgtaaggttc ttttgtatcg
    18481 atatcaacac tttgaagtgg cttgtacaat gtaggaatgg gtttcatgac cccgcgaatg
    18541 acaagtggtt cgccattggt cattccgcct tcgaagccgc ctagattatt ggtacgtcgg
    18601 aaatagcctc tttcttcttc ccataggatc tcatccatca cttctgagcc tggtaatgaa
    18661 ccagaagtga atccgacccc aaattctacg cctttaaagg cattgatact aaccacagct
    18721 tgtgcgattt tggcatctag cttcgtgtcc cattgtacgt agcttcctaa tccagctgga
    18781 acgcctccaa cgagcacttc tacaattcct ccgatcgtat ctccattttt ctttgtctga
    18841 tcgatcaaat cttttattct ttgctcaact gctggatcaa caactcgtac ttctgacgct
    18901 tcagaaattt ctttgatttc ttgaatcgag atatttccag gtatttctgc ttggattcca
    18961 ccaagacaaa tcacgtgtcc tgctacgatg atgtcaagtt cttccagaat ttttttggca
    19021 attgcgccga ttgctacacg catggtcgtc tctcttgcag aggaccgttc aagcacattc
    19081 cgaagatctc gatgatggta tttcataccg cctaccaaat ccgcgtgtcc tggacgcgga
    19141 cgtgcaactc gccgcagtga ttggtctttt tcaggcactt ctgctacaga catgacagtt
    19201 gtccaatttt tccaatcttt attttctacc actaaagtga caggtgaacc aattgttttg
    19261 ccgtgacgga tgccagacgt gatccgaaca cgatcttttt cgatcttcat ccttcctcct
    19321 ctgccgtaac cagcttgtct gcgagcgagt tcgtgattga tttcttcttc tgacagaggt
    19381 aatcctgctg gtagtccttc aataatggct gttaattctg gtccatggga ttctcccgca
    19441 gtcatataac gcatcttaca gtcctcctaa gtaatctttg aatgtctctg tgggaacagg
    19501 aacgattttt gcttgcccaa tcttttctag caagatgata ttcaattggc ttcctcttgc
    19561 tttcttatca tgggttatcg cgtggaataa ttcatctgga tgacttagat cgtacgtaat
    19621 cggcagatgg aatttttgaa gtatcctttc taaagcagct gtcgatccag ttggagacaa
    19681 gccgattttt tctgcatgag aagtgatggc taccattcca atagctactc cttctccatg
    19741 actgactacc ccatatcctg ctgtattttc aattgcatgg ccaattgtat gaccaaaatt
    19801 taaaataagt cgatttcctt ggtcaaagac atcttcttcc actacttttc gtttgatttc
    19861 caacgtagca gtaatgattg gaacagcatg ttccagaaga tctttttcgt ctttcagctc
    19921 gttcagctgt ttccaaagcg ttgcatctgc tatagctgct gatttgatga tttcagcgat
    19981 tccttctcgt aaacgacgta ccggcaaagt ttttagaacc tcaggatcaa tcaatacacc
    20041 agctggctgg ctaaatgttc cgacaaggtt tttcgctttg tttgtattga ctgctgtctt
    20101 cccgccaata ctagaatcta cttgtgcaag tagcgtagtc ggaatttgaa cgaaatggat
    20161 cccacgcatg aacgtcgagg ccacgaatgc tgctagatca cccaccattc ctccaccaag
    20221 tgcaagtatc ccatcgctgc gggtaaaatc attatctgct aaaaaatcgt ataactcagc
    20281 tgcttgttct aaagatttac tggtctcacc cgccggtacg attgaaagga ctggttcaaa
    20341 attagcttgt ctcaattgga acatgatttt ttctgcatat agtggagcaa cgtttgtatc
    20401 agtgatcaca gctacttttt gaggtctcca aatcgtttga agccatgatc cagcctgttc
    20461 tagtgcgcct ttttcaatat gaatatcgta tttttggtta tcaacatgta cagtaagcat
    20521 tcgtttcact tctttctttt aaaaagctgg aattaatcga gtgtctgaat cttttccatt
    20581 gcttctttca tgatcgcaac ttctttcatc atgcgtgagt aagtcttttc attcaacgat
    20641 tggggaccgt ctgaccaagc atttgcagga tcaggatgga tctctacgat catgccatct
    20701 gctccgcttg ccacacccgc acgagccatt ggtggtacaa gttcccaaat tcctgtacca
    20761 tgacttggat caacaatcac agggaaatga gttaattttt tcatcaatgg gacagcactt
    20821 aaatcaaacg tattacgtgt cgctgtttcg taagtccgaa tcccacgttc gataaaaatg
    20881 acaggagatt tgtcttcgac tgcaatgtat tctgcagcat taagccattc attgatcgta
    20941 ccggaaattc cacgtttcaa tccaacaggt ttacctgttt taccgacagc agatagcagt
    21001 ttaaaatttt gcatattacg tgcgccaatc tgtaggatat cgctgtactc agccaccata
    21061 tcgatatgcc cttcatccat cacttcagta atcactttca ttccaaattc atcagccgct
    21121 tgacggatgt atttcaatcc ttcttcttct aaaccttgga aagcatatgg agaagtacgt
    21181 ggtttgaagg caccacctcg cagaattttt gcgcccccgg ctttggccat tcgcgcacat
    21241 tctctgattt ggtctaatcc ttcgatagaa caaggaccag ccatcgtcac gaaactgccg
    21301 tcaccaattt ttactccgtc tacatccacg actgtattgc caggatggaa ttctcgagaa
    21361 gtcaatttgt atgtgtttaa aatacgcaca gcattttcta ctccttcata gcgtgtaaat
    21421 gctccttctt gtaaacttcg cgtatcacct tttagtccaa tcactactcg ttctgttcct
    21481 tgatcgattg agactttgaa tccttctttt tcgatatgat cgacgacttt ttttatttgt
    21541 tcttccgttg cttctttttt cataattact atcattgttt ttcccgcttt cttttgttta
    21601 cttatctatc ttggctgatt ttctctactt tttcaaggtg gttttacatt aattcctact
    21661 aaatgaccgt gtcctgttgt tctcattttc gctccttctt tcctacttat gacccagata
    21721 atcaacaaaa aaagatgtcc ctgtaggaaa ttgcctctac agtgaacatc ttcaacgagc
    21781 cttaaaaagc gctgcaaaaa tataaaatag ccactataga tgaatttctc tacgtggctg
    21841 taagtcgtgt ttaaaaatct ttagccatca tagatacaaa cctggtttgt ttgtacccac
    21901 gaagtcatga atacaaacct atctaaaata gctaaagtaa tacgtattca gttttgtaag
    21961 ttttctagat ttcataaaaa atcgctccaa actgatgtaa gaattgtacc tagtatagac
    22021 ataaaaaaat cgactgtcaa tcatttttat gaaacttttt ttaattttct gatagttaac
    22081 tttgtttttc agaaaaataa caattggttt tattgaagaa aatagtcatg aacaaaagta
    22141 tctgagaact tttttactct cttgttcatg acatatagaa taaagcagct ttgtcttgta
    22201 aactccgttt ttcaaataat aatctaaaga ttgctactga ataataaagc cgatttcatg
    22261 gtcctcttcg ctgctgattc ggtaaggtga ctcaacatcc gctccccagc tattgatacc
    22321 cccgactcct cttacttttg caaaaatcgt aagaaccgtt cgtctttctg gcggtagttc
    22381 ttctatatgt gttgcctgtt ccagttcttc tgctttgaat ggtaaagcgg aaaaagcaaa
    22441 tggcgtatcc tgctgttcaa atcgcaacga aaaatcttct tgatctttat ccgtattatc
    22501 caacgtttga tttcttgtta gttctaccca tttcgtttcc atatgcatgc cgcattcttg
    22561 gggaacaagg tatggggaaa cggggagtcc tgccacttta taaatacctt cgacaccacc
    22621 agccatccga tccggatatg tttcccctga taggccttca tactcaaaaa attttgcttt
    22681 cgttggcata atgaacctta aacccaatgc gggtaattcc ggtaatcctt tttgtccata
    22741 ataatgcata ttgacaagca ttttaccctc tccagcgatt tggtaggaaa ttgtcacttg
    22801 ggtttttggt actgtgttga tttccagtgt aaaaatgatt tcaaccgttt cagcgtattc
    22861 attacttgaa tattgattat ttactggagc aatcggcaaa tcgatctttt tattgtccac
    22921 cagtacttct atttctttga cttttggata caatccggct cctaaccaca taccggattt
    22981 aaatccaaat ccgctacctc tgtcattatc ggtcgttgct cgccaaaaaa ctggaagtgt
    23041 ttcccggtat agccattctt ttccgttttt attgagcgat tccagtccgc ctcttgtata
    23101 agaaaaaata taatgcgtat tccccgattt gacacctaat gtacagtcgc cgaagacgat
    23161 tgcaactttt tccgtatcca tatgactttt atttactgta tttttcataa taatatctta
    23221 cctcctgcat ggcgggtttt tcttgtccat ctgcaaaaac gatcccattc cctgagaatt
    23281 catagtcact tggtttatcg tcaaagtcac cgccatagcg catcacttct ctgcctgtga
    23341 ttggatcagt cacttggatc gcctgatctt taaaatccca tatatagcct ccttggtaca
    23401 tttcataacg atcaagcaac gtcatgtaag aatccattcc acctaacgaa ttccccatgt
    23461 catgcatata ttcacataag atgaacggtt tttccgcttt attttcaagg tagtcaatga
    23521 tctcttctgg tggcgcatac atgcagcttt ttacatctga aatcgaatct tcgaatgctg
    23581 gatttggaaa attcccttca taatggacaa gtcgatcggg gtctactttt ttgaagtaat
    23641 cgttcatttg tcgaatgttt tcttccgcat aagattcatt tccaagagac caaaaaagaa
    23701 tacttggatg gttttttaat gtttcgaaat tcgtttttgc tcgatcaaga acagccgcct
    23761 gccactgagg tactgcacct ggtacgttgt aagaaggctc aaatgcgccc attttttgcc
    23821 atgagccatg ggattcgagg ttcgtttccg ccatcacatg gattcctgct tggtcgcata
    23881 aataatacca agtgatctgg ttggggtaat gagatgtccg tacgccgttg atctttgcat
    23941 tttttatgat agccaaatct ttttccatat cttctatagt gatggcgcgt ccttttttcg
    24001 gatgccactc atgtcgattt accccgttga taatcatccg ttttccattg aagtagatga
    24061 ttttatcttt gatttcgatt ttacgaaaac cgaaggaata gtcaatatac tccgttactc
    24121 ttttttcttc gtctatcgtc tccaattcaa gcttatataa attgggctga aaatgccccc
    24181 acagtgccac attttcaaat ccatcgatgc gaatcgtcat ttgctctttt aacggatatt
    24241 gctgttgata gatttccttc ccatcaggat ctagtatcgc tacattcagc tgactgtttt
    24301 tggctacttg ctcaaaagac aaatctactt caagtttgcc attttgacat ttgtcatcta
    24361 agcgaggttt gatccaaaga tcttctaaat ggttttgtcc tcgagcaact aagaagacat
    24421 ctctgaagat cccaaaaaat cggaaaaagt cctgatcttc caagaatgca gctgtacttc
    24481 ttttgtaaac ctccacagct agaatatttt cttcttccaa ataaggtgtt aaatcaaatt
    24541 cagacggagt gaacgaatct tcggcatacc cgataaaatg accattcaac caaataaaca
    24601 ttgcttgttc tacaccagca aaatgaatcg agatttgttt tccctttaga ccttcttcta
    24661 atcgaaaagt cgtcaaatac gaaccaaccg gattgtcttt agcagctgaa aagatccctt
    24721 ccgcctcttt ctcagggctt gtcgtgaaag ggggacggcg aaatacatgt ccctcccacg
    24781 gatacatcgt attgatgtaa tggatcttgt cataatttgc taattcaata tgactaggaa
    24841 cagtgatttc atcaaaagaa caggcatcaa aatctttttt ataaaatgtt tttggtcgta
    24901 ccgaaggatt tggcgaataa caaaaacgcc atgatccatt taaagactgt ttaagggagg
    24961 atgtggtttc tacttcttcc cttgttgcat aacaaacatg atcgctatgt gcatttgatt
    25021 ggttcactct aaaaacttgt ggatcatcta accattttat atttgctttc atactttttt
    25081 ccttctctct cataactttt tgaaatgaag cagttctgtt tggaaatcac cttgaaaatc
    25141 ggggaagtaa agtccaactg tcatcaattc ggcccccgaa aatatccgct tcgaggtctg
    25201 ttcctgataa agtgcctcat catctaaccc catcagatat acttcatgga acgctggttg
    25261 agctgaagct agtatcctcc ctaaaaacac aatagcttca tcttgtttag gagacacaaa
    25321 catccatgcg gcaatatttt cttcaaaagg actcgccaaa cgataataat ggccatactg
    25381 gatcaccgga cgaatcgttt gataggatat aatttggtct tttacttgct tttcttcttc
    25441 aggagacagc tttgtcaaat ccagttcata accaaaaaca gcgctcatag ctgtttctcc
    25501 tcttgttttc aacgaagtag atctgtcggt ctgatgattt ggtacagctg atacatgagc
    25561 tgtgatggac gaaatcggat aagcaaggct tgttccatat tggattttca tacgctccac
    25621 tgcatccgtg ttatcacttg tccatgactg cggcatataa taaataaacc cggcatcaaa
    25681 ccgtccacct ccaccagaac agccttccca taagatttcc ggataatcag ttgtcaaatg
    25741 ttcaagtagt tcataaagcc cgagcatata acgatgcgct acttctcctt gtctctgtgg
    25801 gtcaagggta atcgaataga catctgaaag cgaacggttc atatcccatt tgatgtagtc
    25861 aagaggaatc gtatctaaaa tctttctcat ttgtttctca atcgtctgcc gaacatctaa
    25921 ccttgtaaaa tccagtacat gttgtgatct ggaagcagaa ggcattctac ctggctcctg
    25981 cataagaaaa tcaggatgtg ttcgatacag ttcagaatca accgagatca tttcaggttc
    26041 aaaccataaa ccaaatttca atcctttgct atgagcataa tctgctattt cacgtaatcc
    26101 atttgtcaac ttgccttcat actcgaacca gtctcctaat gaagaattgt ccgcatctct
    26161 ttttccaaac cagccatcat ctaatacgaa catttcgatg cctagctcct ttgcttcatc
    26221 aatgatcgcc ttgatttttt cactattgaa gtcaaagtaa gtggcttccc agttattgac
    26281 cagaatcggc cgttcagcaa attgatgacg acctcttgcg attctttcac gtagcaactc
    26341 atggtggatc tgactcattt tgttcaatcc ctgacttgag taagaaagga tcatttcagg
    26401 tgtttgaaaa gactggcctg cattcaattc ccacgaaaaa cgatggctgt tgatcccacc
    26461 gacgactctc aattgattga tctgatcttt ttcaagttcg aaagaatggt tgccggaata
    26521 aacaaattga agtccgatcg cttctccagt attttctgtc gtatgatgat gaactaaagc
    26581 aataaagtta ttcatatggt gactgctcgt tcctcgacgg ctttcaaata cttttgttcc
    26641 agataaaaca gattgccgtg aaatctgtct ttcattgaca tgtgctcctg gcaaagcaat
    26701 gacttcatca aatcgcctag tatgggcaaa gtctagctgg aaactagccg ctttttctag
    26761 tttgattgtt tctccggttt catttcttat ctttacagat cgtgtgatca ctgctctatc
    26821 agtaaatatg gtatagaaca aatcgaaata aatcgctgtt tctctatcct taagtgaaat
    26881 caccaacgtt tgtgcctctg acttgtccat cacataagtt tgaggcaagc cttcgatctc
    26941 tggcttccca tctgtaatat aatggctgtc atatctcaga tccagtaagt ctgatccatt
    27001 cttgcgctga atgatcgatg cgggcgttcg aaagtccatg ctgccatgag aagagtattc
    27061 ttgcggtagt gtatctttcg acagagaccg gtcaggattt aagggaacat ttcctgaaaa
    27121 tccacgatct cttcggggat aatttttatt gtctttgtac tgcttgactg gtttgccaaa
    27181 ataaatatgc gccaatacat tgctttcttc tatctttatc agataagaaa gaaatgtatt
    27241 tcgtaaatgg aagactcggc tcttttcatc aaataagatg aaatttttat ctgtttttct
    27301 atgcgtaata tccatcattt cactcccaac aaaacggaaa ccgtttactt ttttttataa
    27361 ttcctgtata ctgtttacta aacaattttg tcaataaaaa ttttttattt ttttgaggag
    27421 tgtgtaaaaa tggttggaat tagagatgtc gcacgaaagg caaatgtctc tcctgctaca
    27481 gtttcccgtg tgttgaataa cgatcagacg atccatgtgg ctcagactac tcggcaacgg
    27541 atagtagagg cagctgctgc gttggattat gacatcagta ctcgtaaata tatcaaaaag
    27601 agaatgcctt cgattggtgt gatctctacg atcggcaaag cgagcgaaga acaggatatc
    27661 tattacaaac atttgcgagt agggatggaa gaagaagctc gacgtctgca tttagggatg
    27721 aatcgaatct ataatctatc tgataatcct aaacaatggg aagatctaga tcagttaggt
    27781 gcggtgatcg ttgttgggac tgttacgaaa gaatcgatta ccgccttgtt aaaacaaaac
    27841 atgcaaatag tcgtcgtgga taaccctgac atccagcaag aggtcgatat ggtgtatgca
    27901 gatcttgaac ggatgactaa aaccgtactg gaattgttct tagaaaatgg tcataaaaga
    27961 atagcctata tcgggggata taaagtcgat atggatgaat tcggtgggaa gcagatttct
    28021 ataaatgaaa agaggatgcg tgcctatcag cattttatga tcgatcatca cttagaaaaa
    28081 tatatgtctt atcatctagg tggctggaca gaaaaacaag gtgaggtact tgcgactaat
    28141 ctattagaaa atgaatcccc tcttcctact gccattcttg tcgggagcga tccaatggca
    28201 attggtgtct atcgggcatt gaaacaaaaa aatatccaaa ttggagaaga gattgttgta
    28261 gcaagctttg ataatatcga gacaatcgca aacctctccc ctggcttgac cagtgttcaa
    28321 atcaatgcga aatcaattgg gcaagcagct gttcgaatgg cattggagcg aattgacggt
    28381 atacgggacg aaccaatcat tttgacttat cctgcacgat tgattgttag ggaaagtttt
    28441 atcccaagaa caaaaaggta ttgaaagaga ggttgtgaaa agccgcttcg tttcttcata
    28501 ctcaaaacga aacggctttt tcacaacctc ttacttatac ttattcacaa aatccaatgt
    28561 ctgctggtaa caattttgcg attcttttag cgtgtaatca aattggtatt catgggtaat
    28621 ctcttttttt gtatctgtat aaaacaagga ttgcacgggt acctttaatt ctgtcaaccg
    28681 attttctaat gcttgacctt gctcctggaa tgagtatgca tttccgtcag ttatatacgt
    28741 tggcggaaat tccttagaaa catggtcagc cacactagct tctttcaatt gctcactcgt
    28801 tttccaatct tttgttccaa tcaacgacca cgcaacggtt ttgacgaaaa acttcataaa
    28861 tcgatcatcc gaatgctgct gtgctgttag cttcaaatca acaggtccgc aataagaaat
    28921 ggttcctttc agactatctt ttggaagtag atgtttgatt ttcatttgtt tagcatacgc
    28981 atcattcgtt tgtatagctg catattgcaa tgcgatttgt gaacctgcac tatctccacc
    29041 aaaaaataat tgttccatgt ctagcaattt gtcgtctttt tcttcagcta ataaatcttt
    29101 gatcagttca ttcacttgaa gaacttgatt agggtattct gaatcaggcg ctaattcata
    29161 attcatcgca accactgcga tgttggcgtc tgaaactaat tttgtcgcaa attctttgac
    29221 acccgattta tctccgccga cgaatcctcc accatgtacc caaaatagaa caggaacagg
    29281 ccccttgctg ttttttggat agtagatgtc ataagtattc tctttatact tggactcata
    29341 cgtcaaatct gtttttttcg ccacgttttt ttctgcttga tcgaacgttt ttttatcagt
    29401 gatttgaaca gtatttgaaa acatatggtt gatcaagaat gctccaggtc tgggggaaag
    29461 ctggaaggca agaaagattg caaacgcgat cccaagaatg attccgaaga accatccgat
    29521 aaatttaaga attttctttt tcataaggct ccctcagtag ttagtattaa gcattctgat
    29581 tataccatag tgttatttcc tatcaagctc tcctagatga tttaatgatt ttccccaaac
    29641 ttcttctgca atgcttttga caaaagaaat tttttccatt gttcttcaaa caaaacattt
    29701 tcttcttctg ttgaagcaaa tccacattga ggacttaagc acaaacgatc caaaggcaga
    29761 tatcgtgtcg cttcgtagat ccggtcaatc acttgctggt gctcttccat ttcgccattt
    29821 ttcgttacag tcaaaatcta agacaactaa tttatcttca gagactttct ctaaaagaac
    29881 aaaactccca gcacgttcac tatcgtattc taaataatag gcacggacat tttcttgagt
    29941 aaaataatgg gtctgctacg tcgtcatccc ccctgatgcc gccaaaatcg aataataatt
    30001 tccgcgtcaa acatgtatat ttagtgttga atcatttgag aatatgaaaa taaaaatctt
    30061 tttgatcaat cagttaatca aattgaaata acgaaaaatc tgagacagaa tgacgttcat
    30121 tctgacccag atttgatttt gcacaactca acagtcctta ttggcaaatc gccaaaataa
    30181 tgtagactaa ctaaaaagac taagaaacaa taacaaaagt taacacttct tagtctttct
    30241 ttagcacgtc tatttattaa agattttagg gccttttctc atgtttttac gatcattctt
    30301 aggtgtttcc atttgtttgg atcggcctcc accttgtttc tttttgatca attctttcat
    30361 tttttctttt tggtccattt ttattctcct ttaacgaatg aagcgactaa ttcgatatga
    30421 tgggtttgcg ggaaaagatc tacaggctga actttcttca cggcataacc tgcttctgca
    30481 aataacttag catctcttgc aaaagttgcc ggattacatg agatatagac gattcgttct
    30541 ggtgacattt cgattgctga ttcaataaaa tgatgatcta atccttttcg tggagggtca
    30601 actacgatca cagatggttt gatccctttt tcttgccatt ttttcataac tttttctgct
    30661 tttccgactt cataatgaac attttcgatt ttattattta aagcattgaa ctgtgcatct
    30721 tcaattgctt ctggaataac ttccatccca tacaccttat ccactctgtc tgctaaagac
    30781 aagccaatcg tacctattcc tgaataagcg tcgatcacaa tgtctttttt atctaactcg
    30841 gcaaactcga tggctgtttg gtacagatac tctgcttgtt gagtatttac ttgataaaat
    30901 gactttgctg agattcgata ggtttttcct aatagctgat cttcgatata gtctctgcca
    30961 tataaaactt tttctttgtc tcctaaaatc acatttgttt tttcttcatt gatattttgg
    31021 atgaccgaaa ccacttctgg caattcttca tgaatagctt cagcaatttc cttggattta
    31081 aagaattttt ctttacgagt aactaaaacg accatcattt catgggaata atgaccacga
    31141 cggataatga tgtgacgaag ctgtccttca tttttttctt cattatatcc tcgtacttgg
    31201 aaccgttgca agatatctct gactactttg attgcttgat cgatgacagg atcttggata
    31261 taaaaatctt cgatagggac tagatcatgg ctattctttt tgtaaaaacc ggtggctaac
    31321 tgtccatcga tacggcgaac agggatctgt gctttattac ggtagccgaa tggttctgcc
    31381 attccgaccg ttggaagtac aggaacttct ggcatcttag caatcttcgc cattacatgc
    31441 tctacttgtt tttgtttgaa gacaagctgt tgttcatact tcaaatgggc taaaggtgcg
    31501 atacctatgc gaagtaatgc attgttttct acaggctgac gatcaggtga ttgtgtaata
    31561 aatgtttcga cttttccata tccaaactta ttgcctgctt ttactactag tatttctact
    31621 tcttctccag ggagtgcatt ttcgataaat aatggataac catcgatttt tgctaccccc
    31681 attccttcat aactcaagtc gacgatttcg actgtatatc gttcgttttt ctttactatt
    31741 tgctgttctg tcatattttg ctcctttaag cctatttttc aatcctactg aactctacta
    31801 taaatcagct aattacacaa ctaaaaccgg cactgacctt actacgttca gcaccggctt
    31861 ttgattaatt cttttgatta ggtgtttcgt ctgctatttt tccgtcaccg tcgatatctt
    31921 catccgttaa acgttcgact tcttttacga attctttgct gacaacctct aattcttctt
    31981 catctgtacc tgtgattgct tcatcaggaa tctgatcggt attggcaaag aactcaatgt
    32041 gttgatgaag attttggaaa tgcatcggtg cttccccgcc gtattcacca tctaagttga
    32101 tcattactgg tcgattgata tcatcttctg tttcaacgaa caaactgctt gttttggtat
    32161 agattattct tggatcatcg acatgtcgac cgccattcag catgagtgct gcaatatgca
    32221 agatctcaaa gatatttgct gtcttcacaa tgattaaaga aaacttccca tcatccaatt
    32281 tggcatctgg cgcgatctgt tcgaatcctc caacagagtt cgtcagccct aggaaaaaca
    32341 tcgaagcatt tccgatatat tccccttcat catacttcaa gcgcattttg attggcttta
    32401 ctcgagggag catctctgct cctttcgcaa gataagcaag ataaccaaaa atactcttta
    32461 gttctgatgg aacttcataa gtcaattctg tcaaatagcc acctgcagcg atattgatga
    32521 agtaactgtt atcagaaagg ccgatgtcca tttttacggt ttggtgtttt tttatcactt
    32581 ctgctgctgc tttaatatta tctctaggaa tttttaatgc tcgagcatag tcgttcgttg
    32641 taccagctgg gatgatggcc attttaggac ggtgttcaag cggagcgatt ccattaacca
    32701 cttcgttgat tgtgccatcg ccaccagctg ccactactag atcaaaacct agttctgcga
    32761 ctctacatgc ttcattcttg gctgaatctg gttctggtgt agttgcatag gcgctggctt
    32821 caaatcctgc ttcttctaat gcctgtagga tatccgccaa attttttttc aataattctt
    32881 ttcccgaggt ggggttataa attacgcgtg cttttttcat tttcagcctc tatcgtttcg
    32941 ctaattcatc tttaagtagc ttattcacga caccaggatt tgcttgtcct ttagttgctt
    33001 tcatgatttg accgactagg aagccaaccg cacgatcttt tccatttttg aaatcatcga
    33061 cagattgttg gttgttatcc aaaatttcat taatgattgg cagtagtttg ttcggatcag
    33121 ataattgcac ccaaccattt ttttcaacta cttcttgggc ttctccgcca tttgtgatca
    33181 attcacggaa gacttttttg gcgatttttg agctgatcgt tccatcggcg atcaaacgaa
    33241 tcattcctgc taagttctca ggtgtcaatt ttgtctcagc taattccagt ttctcactgt
    33301 tcaagtaagc agaaacttca cccatcaacc agttagatgc ttgcttggca tctgcaccat
    33361 tttccaaaac agcttcaaaa aaatcagaca tttcttttgt aagtgtcaat accattgcgt
    33421 catactctgg aagtccaaac tcacggatat agcgttcgcg acgagaagct ggcatctcag
    33481 gcaaactagc ttttactttt tgaatccatt cgtcatcgat cacgaatttc gggatatcag
    33541 gctctgggaa gtaacgataa tcactagacc cttctttgac acgcatcaaa actgttttat
    33601 tcgttgtttc gtcaaaacgg cgtgtttctt gttggatttc tcctcctgaa agaagaactt
    33661 ttgcttgacg tttttcttca aaagctaaac cttttttcac gaaagataaa gagttcaagt
    33721 ttttcaattc tgctttcgta ccgaactctt cttgtccata agggcgaaga gaaatattgg
    33781 catcacagcg catagagcct tcttccattt tcacatcgct gacttctgta aattggataa
    33841 ttgatcgcaa tgcttctaga taagcgtatg cttcttctgg tgaacgcata tcagcttcag
    33901 aaacgatttc gatcaaaggc gtgccttgtc ggttcaaatc aacgtaagaa taaccgccaa
    33961 taccatgcat gttttttcca gcatcttctt ctaaatggac acgttcgatc cggatttttt
    34021 tctttttacc ttctacttcg atttcgatcc atccgtcatg accgattggt tgatcaaatt
    34081 gggaaatttg atatgctttt ggattatctg ggtaaaagta atttttccgg tcaaaatgag
    34141 tatctttaga gatttcacag tttaatgcca aagctgcttt catcccgaat tccagcgcag
    34201 ctttattcat tactggcagc acgcctggat aaccccagtc gatcacgttt gtattgctgt
    34261 ttggttctgc accaaaatga gctggcgctg gagagaaaat ttttgagttg gtttttaact
    34321 cgacgtggac ttctagtcca atgactgttt caaaattcat tcgtctttcc ctcctaaaat
    34381 agctggttgt tgtttatgga attctgttgc ttgttcaaac gcatatgccg cttgatacat
    34441 cgttttttca tcaaaataat taccgatgat ctgcaatcca actggtaatc cttctgataa
    34501 acctgccggt acagacatac ctggaagtcc agccaagttg acagggatcg ttaagatgtc
    34561 actcatgtac attgtgattg gatcgttaat gttctcaccg attccgaatg caactgttgg
    34621 tgaagatggc ccgatgatca agtcataatc tgcaaagact ttttcaaaat ctcgtttgat
    34681 caatgtacgg acttgtcctg cttttttgaa gtaagcgtca taataacccg cgcttaagga
    34741 gaatgtacct aacatgatac ggcgttttac ttcttcaccg aatccttctg aacgtgagtt
    34801 gacatataca tcatctaatg atttcacatt ttcagagcga taaccgtagc ggataccatc
    34861 gaatcgttgc aaattggaac ttgcttctga tgaggcaatg atataataaa cagccacacc
    34921 gtattttgaa tgagccaagc tgacttcttc cacaacagca cctaatgaac ggaatgtttc
    34981 tgctgctttc aatacagctt cttttacgcc aggggccaca ccttcgccta agtattcttt
    35041 aggtaaagca atcttcattc ctttgatgtc gcctgtcagt ccctctgcaa aatcaggaac
    35101 tgaaacgcct gaagaagtac cgtctttttc gtcataaccg ctgatagctg tcaatgctaa
    35161 tgcattatct ttcaccgtac gggtcattgg tccgatttgg tcaagagatg aagcaaaggc
    35221 aatcaaacca aaacgtgaga cacggccata agtaggtttc atccctacga tgccgttaaa
    35281 agctgctggt tggcggatac ttcccccagt atcactacct aaagaaactg gaatttgtcc
    35341 agctgcaact gctgctgcag aaccaccaga agagccacca ggtacttttg ttgggtccca
    35401 agcatttttt gttttcttga aataagaagt ttctgtactt ccacccatag caaattcatc
    35461 catgtttagc ttaccaacag ggatcatatc tgcttgatag attttatcca tgaccgttgc
    35521 atcataaatt ggttcaaaat tgtaaaggat cttagatgca gcggttgtca agatatcttt
    35581 tgttacgata ttatccttga taccaattgg aataccagca aggacgttgc tttcatcaat
    35641 ccctttttca tctaaagctt ttgcctgttc caatgctttt tcttcgttca atgtaatgaa
    35701 tgcctcgacc tcaggctctg tttctttgat tcgttcaaat gttgtttttg tcaaatcttg
    35761 tacagtgatt tctttcgata caagcatatg atgcagttct tctagagaac gattgtgtaa
    35821 ttctgtcatt atgcgccagc ctccccatta tcgatgattg cgggtacttt gataaagccg
    35881 tcttctgttt ccggcacatt tttcaataat tcatcgcggt tccatccagc ttgcgcccga
    35941 tcttgtcgca tcacgtttac tgtttcaacc acattcgacg taaatggaac accttccgta
    36001 tctacttctt ccagcatttc aaccatatcg atgattttac ctaattggtc ggtaaaactt
    36061 gcaagttctt catctgcgaa cgcaagtttt gctaatttgg caacgtgttt cacttgttct
    36121 tcactaatcg ccatactacc ccttctttct aaacgagtta aaaactttgc tctctatttt
    36181 aacacaagag tgccgtgtct gaaattgttt attgaaattt gtctgaaaaa actcattttt
    36241 cattcttcta ctgagcgact tttagccaat gcatctgcca tttgatcttc tgtccaaact
    36301 tcgattccta attcttgtgc tttggtcagc ttgctgccag catcttctcc tgctaccacg
    36361 atatccgttt ttttcgatac gctaccagtc actttcccgc caagattttc gatcgtctct
    36421 tttgcttctt cacgagtaaa tcgtgttagt ttaccagtaa ggactactgt tttttcttta
    36481 aaaggagact cgacttcttg caattgggca tttcgaagcc ctttgtattc gaaattgacg
    36541 cctgcttgtt ttaattcatt catcaattca tggacttctt cgttactgaa ataagtgact
    36601 acactgtcgg caatgatatc accgatcgta tcaagcgcaa taatcgactc atagtcactt
    36661 ttactcaatg tttctagatc accgaaatgt tctgctaaaa tttttgctgc tttcgctccg
    36721 acatgtcgga ttcctaaccc gaaaatcaac cgctcgaccg aattatcttt gctgttgtcg
    36781 attgctgtca aaatattatt tgctgatttt tcttttattt tgtccaacgt caataactct
    36841 tcttctgtca atttgtaaag atcagcaaca tctgctacta gttttttatc atacatctgt
    36901 tctagtacgc gcggccccaa cccatcgata ttcatcgcat ttcttgaaac aaagtggttc
    36961 aaaccttctt tcatttgagc agggcattta ggattgatgc accgtaaggc tacttcttca
    37021 tccaaatgga caagttcact tccacaaact ggacaatgtg taggcaattg gtattcttcg
    37081 ctgtctttag gtcgtttatc taacacgact tgcgaaactt ctgggatgat gtctcccgct
    37141 ttataaatca gaactgtatc tttcaagcgg atatccttca acttaatata atcaccgtta
    37201 tgcaggctgg cacggcttac tgtcgttcct gctactcgga ctggtgtcat gatagctgtt
    37261 ggcgttacta cccctgttcg accgactgtc cattcgatgt tttcgattag cgtttcaact
    37321 tcttctggcg gaaacttgta agctgctgcc catctcggtg ctttgatagt aaaaccaagt
    37381 tgatcttgta gcgagaattc attcactttg atgacgattc catcgatttc atagggcaaa
    37441 tccacacgtt tgtcatgata ttcttcaatg tatgaccaca cttcatcaat cgaatgacat
    37501 agacgttttt cccgattcgt gtggaatcca attttttcta gctcttctag cgcatcatac
    37561 tgggtttttg cttgcatagg accgaaatca gctactgtgt ataaaaaagt gtccagattt
    37621 cttttcgctg tgattttaga atctaactga cgcaaagaac cagctgcggc gttccgagga
    37681 ttcgcaaaga tatcttttcc ctctgcttct ctgtcttggt tcaattggac aaatgaccgt
    37741 tttggcatga aacattcgcc tcttacttcg atgttcattg gttcttttaa tttgattggg
    37801 accgaccgga cagtttttag gttttcagtg atgttttctc ctacagttcc atccccgcga
    37861 gtcgcacctc tcacgaaatt tccatcttca taacgcaaag aaacggaaag tccatctatt
    37921 tttagttcac agcaatagtc aactacacgt cccactgctt tttgtacacg ttgatcaaaa
    37981 gctatcagct cttctttgct gaaaacgtcg ttcaaactgt aaagcggaat atcatgagtg
    38041 actttttcaa aaccttctaa tacttttccg cctactcgtt gagtgggaga atcagacgtg
    38101 atcaaatcag gatattgttc ctcgattgct actaattctg cgtattcttt atcataaaca
    38161 tagtcttcca ctgttggttt atcttctacg tagtattcgc gagaccattg gttcagtctt
    38221 gtacgaagtt cttctgctcg tttagcagct tcgtcaatcg tcatttcatg ttccatcatt
    38281 taccctccac tactaagctt tttcaattgg cgcaaaggca gccaaaagac gttttactcc
    38341 ttgacttggg aaagccacat ctagttctag atccttcgac gtcccgctta ctcggacgac
    38401 tgttcctaga ccccattttt tgtgtttgac tttatctcca ggtttccagc tgttattttc
    38461 ccctccagta gcacttttag agggaacaac cgctgtctct ggctgtttat agctatatgc
    38521 tgttttttta gcgaatacag gcgttttttt aggcgtagga cgcatgcctt cgatttccag
    38581 taactcctga tcgatttctt ctacaaaacg agaaggtcgg ttatattgcg tccgtccata
    38641 taatgttctg gagaaagcat ttgttaaata caacgcttct tctgctcgcg tgatccccac
    38701 atatgcgaga cggcgttctt cctccagttc gctttcttcc atcaatgctc gagataaagg
    38761 aaaaaccccc tcttctagac caatcaggaa tacaactgga aattctaatc ctttggctgc
    38821 atgcaaagtc atcaatgtca cttgggaagc atcttcttct aaattgtcaa tgtcggaaac
    38881 aagtgccaga tcatttaaga agaccgttag tttttcttct ggtgcatcag cgtcttcttc
    38941 attttgctgt tcgaattgtt tgtcgaattc ttgtgtgacc gttaaaaatt cctccaagtt
    39001 ttcgatgcgt gcttgtgctt ctaatgtatt ttggattttt aagtcttcta gatatccgct
    39061 acgatccaaa acctctttcg tcaattctgt cactgtcaag tatgggatca tctgagtgac
    39121 ttcttggatc atctctccaa atgcacctaa ttgctgtcct gcttttccac cgatatttgc
    39181 cagatccaca ttttgcgctg cttcaagcag tggccattca tgaagagaag caaaactgcg
    39241 tagtttttcg atagatcctg gtccgatgcc tcgtttgggc gaattaacga tacgctcaaa
    39301 actgattgaa tcttgaggat ttaccagcac attcaaatac gctaaaatat ctttgatttc
    39361 tttacgatcg tagaacttgt gccctccaac cattttataa ggaatatttg ctttcaacag
    39421 agtttcttcc attacacgag attgtgcgtt cgtccggtac aagatggcaa agtcgccgta
    39481 attccgatga ttgcttcgaa tctcttcttg catccggtct acgataaaac gggtttcgtc
    39541 tcgttcatta tctgcacggt agtaagtgat cttgtttcct tctttgtttt ctgtccacaa
    39601 gttttttggt tttcgattgc tattgttttc aatgacttgg tttgctgcgc taaggatgtt
    39661 tttcgtggag cgatagtttt gttctagcaa aattactgca gcatctggat aatctttttc
    39721 aaaatccaag atgttctgca tatctgcacc gcgccagccg taaatacttt gatctgcatc
    39781 tcccacgacg cacaggttcc taaatctacc tgccaataaa ttgactagcg tatactgtgc
    39841 gtgatttgta tcttggtact catctacatg aatataatgg aatttgtttt gataatacgt
    39901 gagtgaatca ggatgttctt caaataatcg aatcgtattc atgatcaggt cgtcaaagtc
    39961 catacattga ttatattgaa gctctttttg gtaagcagca taacattttg ccgcaatctc
    40021 ttcgtaataa ctgccttgca tttttgcaaa atcctgaggg gtctgcaggc tgttttttgc
    40081 ttgagagatt gttcctaata tacttcgagg atcatatttt ttcggatcaa tgttcagttc
    40141 ttttagtatc cgtttcatca aggtcagctg ttcagaagaa tcgatgattg taaagttccg
    40201 gttatacccg ataaaatcaa catctcttct taaaatacgc acacacatcg agtgaaaagt
    40261 cgatacccag acatcttcgc ctccagatgc gagaatcgca ttgacacgtt ctttcatttc
    40321 ttttgcagcc ttattggtaa aagtaatcgc taggatgttc caaggattga cttctttttc
    40381 ctcaatcaaa taggcaatgc ggtgtgtcag cactctcgtc tttccacttc ctgcacctgc
    40441 cattagcagt aatggtccgt cagtgtgaag aacagcttct ttctgacggg ggttcatccc
    40501 gtttaataat tcagctttgg atgacattaa caacatcctt tcttttatca atcttgttaa
    40561 ttatagcatt ttcttggctt tcattaaact agctagttca aaatcatttg tttcttttta
    40621 tggatttttc cttgtcaatt cgttgatttc gcgctaaatt aaaagaaagc gaggcgtttg
    40681 aatggaaaaa aaaggaaaaa tcaagaaatt agataagact cagatatatt ttattctaaa
    40741 aggaatattt gttggactgc tgacaggaat cgtcgttagc ctgtttcgat tatctatcga
    40801 aaagctaagc gatttagttc gaagtatcta tgaaatgagt cgggaacagc cgatttactt
    40861 aattggccta gctatttgct gcatccttgc agcatttttc gtgggttatc tggtcaaaaa
    40921 tgaaccggat atcaagggaa gcgggattcc acaagtagtg ggacagcttc gcggggaatt
    40981 atcaatgaac tggttctctg ttttatggaa aaagttcatt ggcggtgtac tttcagttgg
    41041 tgcgggcctt tttctaggta gagaaggacc ttctatacag cttggcgcat ccattggaca
    41101 aggagctgga caattgtttc ggagtccatc ttcagaagaa aagattttaa tttctagcgg
    41161 tgcaagtagc ggacttgcag cagcattcaa tgctcctatc gcaggattac tctttgtttt
    41221 agaagaaatc catcactcct tttctccact tgtttggctg acatcatttg cttcagcaat
    41281 cactgctaac ttcgtctctc tttacttttt cggcttgaga cctgttttat atctaggtga
    41341 ccttccttct ttgccgttga aatattatgg ttccttagtg atcttaggag tacttctagg
    41401 catcttaggt tttatttatc agaatgtctt gctggctttg ccaaaatttt acaaccgatt
    41461 gcctttacca gcttattttc acgggttcgt tcctttcttg ctgattttgc caattggtta
    41521 tttatggcct agtactctag gcggaggcaa tcaaatcgtt ttagcttttg gacatgcttc
    41581 cttgccaatc attatgatta tcggtttgtt tgttcttcga ttcgtttttt ccatgatttc
    41641 ttacggtggg ggtcttccag gggggatttt ccttccgata ttgacattgg gggctttaat
    41701 cggtagcttt tatggaaaca ttatggttga tttcgggatg gatccaatct acatcaagga
    41761 ttttgtcgtt attgccatgg ctggttattt cacagcgatt ggaaaagcac cgctgacagc
    41821 aattatttta gtgacagaaa tggttggctc tcttaatcat ctgatgcctt taggattggc
    41881 tgctcttgtt gcttatatcg tcaatgacct tctcggcggt aatccaattt acgaatcatt
    41941 attggaacgt ctacttggaa atactcagac cgcctcacta aaaggtgcaa ggacaacttt
    42001 tgattttcca gtaacggcag agagttcttt agacggatta atggtacgag acttcaattg
    42061 gcctaaaaat atgctgctaa tctctatacg cagaggaaat caggaaatct tgactcacgg
    42121 tgatacgatc atgaatgtag gagatatttt ggttatcttg actgatgaag caaacttgcc
    42181 aagaatcaag caggaaatcg aggctaaatc ttctatcaca aatttgaagc aatcatttta
    42241 acgaacatgg aaaaactatt ttacaacaac tattcatcta cactacttga ttctatatga
    42301 ttctataaaa aaagaagagg ctgggaaaac ccagcctctt cttttttatt tctatgcttc
    42361 tgctactgca ggagcttttc tcaataaacc ataaatcaca ccagatacga ctgctccgat
    42421 agcaataaac accaaataca tgaccgggtg actcagtaag aatacaacga aaatcccgcc
    42481 gtgaggagcc agtaatttga ttccgaaagc tccgactaat ccgccagtta aagcagaacc
    42541 aataataaaa cttggaatgg cacgaatcgg gtcagctgct gcaaatggaa tcgatccttc
    42601 cgtgacaaac gatagtccca tcacgatgtt cgtcaaacca gcatcttgat ctgttttgct
    42661 gaatttattc ttaaacaaac gtgtagcaac gaaaattgcc aatggaggta ccattcctcc
    42721 agccataaca gaagccatca cgacacttcc gccagttgca acagtcgtag ctaaagttgc
    42781 tgtaccaaac acataagcgg ctttgttgat tggaccgcct aaatctgccg ccatcattcc
    42841 agctaataat gcaccaagta aagcagcatt cgaaccactc atacttgtca agaaaccgtt
    42901 caatgcatca ttgattgctt tcatagggac attgaccagc aacatcaaga aaccagtaat
    42961 cagtaagcca aacactggat aaaagaggat cgttttaatt ccatccaatg attttggtaa
    43021 gttcttgaat aatttacgta aaaatacgat gacataacca gctaagaatc caccaatcag
    43081 tgcacctaag aatcctgcac cgcctgtatt agctaatgca ccagcagcaa atccaacgat
    43141 caaaccaggg cggtcaccga tacttgaagc aataaatcct gctaataccg gcagcatgaa
    43201 accaaatgca gcttgtccga tttggttgaa ccagctagca gcttgattgt aattccctag
    43261 atttgataat tgatcatgtg gcacgccaat aaattggtcg atcatgaaag aaagcgcaat
    43321 agcgattcct ccaccaataa cgaaaggtaa catgtgtgat acgccgttca tcaaatcttt
    43381 gtaaattctt tgtccgatag taccatccgc atttccttct tctgaactgc tttcttttcc
    43441 atcaccatgg aatactggtg cagtaccact aagggctaga ttgatcaact cttctggttt
    43501 acggatacca tcactgacag gacgattgat cagttctttt ccgtcaaagc gattcatctc
    43561 tacttttttg tctgctgcaa cgattacacc ttctgcacgg gcgatgtctt cagcagtcaa
    43621 tcggtttttg attccttctg aaccgttcgt ttcgactttg atctccacac ccatttcttt
    43681 cgcttttttc ttcaaagcat cttctgccat gtaagtgtga gcgatccctg ttggacaagc
    43741 tgtaacggca acaacgaatt ttctttctgg atgagcagaa gcttctgcag cttgtgtttc
    43801 ttgttctgct ttttcttctg cttctttttg ctcttcagct gtttggaaca agtcttggac
    43861 ttcttctggt gtatttgctt cttttaattt tcctacgaaa tctgcatcaa tcagcaatcg
    43921 agatagtgct gctaatgctt gcaaatgtgt gtcgtttgcg ccttctggag ctgcgatcat
    43981 gaaaaacaga taagttggct gtccgtctaa ggcttcataa tctactcctt tttggctttt
    44041 tgcgaataaa actgttgctt ctttaactgc actgtttttc gcgtgaggca tggcgattcc
    44101 atcaccaaga cctgtagaag tttgtgcttc gcgggctaga attccttctt tatatgtttc
    44161 gatatcggaa atccggccgg catcaaacat tttttggacc atttcatcga ttgcgccttt
    44221 tttatcagtc gcttgcaaat ccatgatcat cgcttctttg accattaaat ccttgatatt
    44281 catgattatc ctccttgaaa ctaatcaatt tttgtgattt caacttctgg cagcaactca
    44341 tcaatcaatt cgcgagctgc caagtcatca gaaaaagctg ttgcgcttcc gcaagcaact
    44401 ccccatttaa aggcttcgat tggatctttc gtacggctgt aagccccaat aaagccagca
    44461 atcattgaat cccctgcacc tactgaattt ttcaatgggc gaactaatac attcgtttta
    44521 taagttcctt gttccgtgaa gagcaaagca ccgtctccag ccattgagat cagcacattc
    44581 tgtgcccctt cagctagtaa ttttttccca tacggaatga tttcttctac agattggaag
    44641 gttgtgttgt aaagctcagc taattcgtga ttgtttggtt tgatcaacaa cggtttctta
    44701 acaagtgcat tttttaggtc atcacctgtt gtatcaatca cgaaatctgc acctttttct
    44761 cgaatgatat caatcagttc ttgataaaat ccttttcgca ggctagctgg cgcgcttcct
    44821 gacaatacga cgatatctcc ttgtcctact gttcctaatg cttgcttcaa ctcatcgatt
    44881 tcttcatctg aaatagatgg gcctaagcca ttgatctcag tttcagtgtc tgattttagt
    44941 ttgatattga ttcttgtatc ttcttttacg gttgtgaaca aagactggat ttgttctttt
    45001 tcaagccact tcgaaataaa ttcgccagtg aaccctccta aaaaccctag tgctgtagat
    45061 tgagaatcga tccgtttcaa aatacgggaa acattgatcc cttttcctcc aggtaacttg
    45121 aagtcttcct tcattcggtt caaatcgcct agttttaacc catctacgcg tacgatataa
    45181 tcaattgatg gattaagtgt tactgtgtaa atcattgtat tgcctcctta attgttgtct
    45241 tttcacggaa ttcattaacg aattctaatg gacaacgctc ggttatgatc gtggctgctt
    45301 ccaaaggtgc aacagaggtg aaggacaact ggttgaattt ggtatgatca atcaatacaa
    45361 atgtctcttc ggaatttttc atggctaaac gtttaacagc tgcctcttct ggatccggag
    45421 tcgtgaatcc ttgttcaaga tgggcaccgt tcattcccat aaatgcttta ttaaaatgaa
    45481 aattttttag ttgttctatc gcattagatc ctaaaacagc attagttgcc agctttatcg
    45541 ttccacctaa aataatggta gcaagctcca aatcaactaa atttgccgca tgttgaacgg
    45601 aatttgtcac tactgtgatc tgttttcctt gcagaaaagg aatcatttct aacgtagtag
    45661 agccagcgtc taaataaatg acatcttcgt cattaatggt ttcagctgcc gatttggcga
    45721 tttgctgttt ttcgtgaacg tttttgagtg atttttcact catattctgc tcaaaattca
    45781 ataattgctc tttcttagct ccgccatgaa ctctttctag aaacccacta ttctccagct
    45841 cttgtaaatc acgtcttatc gttgattcag aagcattcaa aaggtttaca agatcttgtg
    45901 atttcacgat tttctgctgt tcaagcaagt ctaggatttt ttgtctgcgt tcctctgtaa
    45961 gcattttcac gatcacctca atacaaataa tagcatattt tttttctact agcaatataa
    46021 atcagtcaaa aacgttcata aaaattataa atcagtcaaa aaaaaataaa aaaccagtca
    46081 gaaagactgg ttttttattt ttttgtctat catcaagccg ttttatcgtt ttttattttc
    46141 gcttcttgtt tttttcatat aaacagaagc aggttttctt tccttatgaa gaagataata
    46201 ataaagtccc atcccgccaa acatgaccaa aaaaccgatg actgatcgaa taggaaaatt
    46261 aggaacaaaa aagagacaga cggataataa tgatgccgga accattattc gataatagag
    46321 ttgtttatcc attttcttca cctcatattt tttgtaaagt aatcaattgt tctaattctc
    46381 ggtaatctaa aaattgcaca cgcagatgct gctcaccttt cttgacatcg aattggatac
    46441 ttcgccgctt tttctttatt cgtttgaagg taacatcaga gagtctatgt ttgatttcct
    46501 ttaacggtaa ttctgacagg gattctgaag gaacatagat tcttaaggat aaaagatact
    46561 cttgatattt ttcatctgtt acctctactt ctagatattc cctaatataa taacaataag
    46621 cttcgattcc attatccaaa gcaacagtcg gatcgataac tttatagcac atcatgcgtg
    46681 atcgattctc gtcaacccaa ggaaaatacg cctgagcatt tagtgttccg cgaacacgcc
    46741 tttctttata atctccttgt tggatatcat aactttttgt tacaaaaaat gaagcattct
    46801 ttttaggaac aggttgcatt tgtgcattct gatactggac agattggatc gtatggtcag
    46861 tgtaaatgta ttcaacgaat ggcggtttca ataaaccgac accattgtcc caagcaagat
    46921 gatcaaaccc aagctggtcc ctaaaatagg attgaaacat ttgattgttt ggcttttgcc
    46981 agttaaaggg gtctcgataa agctggatac atatgacttc gttttctaat tccttcactt
    47041 tttctacttg ttggatgtcg agaaaaatcg gtttagggat gatttgatga taatagcgac
    47101 tataatacat ttcccaacac gaagtgaaac ataaaccttg gtaaaaaaga tcgtatcctg
    47161 gaaattggtt gcaatcgact actacttccc cgttttgttg tttcatttta ggtaaatgtt
    47221 cgatttcatc ctttttctca aacaatagcc gttgagagat ctgttttgta ttgtgataga
    47281 taaactcgct ataagctcgc atataggcga acaccccatg agcaatcatt tttttctgaa
    47341 tgaagtctcg aatcaaaaat tgcttttctt tgaaaacaga gatagacaat acatttttta
    47401 tcaataattg attatcttcc aagcgaaaac tacattcgtt ctcgtcattt cctacaacta
    47461 accaactttc gtctcttacc gatgctagca ttattttttc ttgaagcttt cgaagatcat
    47521 acggatccgc ttgttgtgtg aaagagcgga taaatgttgg ctggatcaac agacgtgtca
    47581 aaatagccca atcgcttatt tcctgttttt tttcttcttc atttaagtct gtgagctgga
    47641 tagtcatcaa taatttatct tcgccaatca ttttctcacc tctttcaaat ctttttataa
    47701 tttaattata accaatgata aagaaaaact aaaactttat gtcttagaaa ccaatttgga
    47761 cgattacatg atagactaag taaaaagaaa caaagaggtg tttacaatgg ggttgaaatt
    47821 tgaacgtaca gataatttag ataaactttt cgaatcattt gctgtcgatc cggaaaaaac
    47881 agttgcacca aaagaagaga tcgatcgatt tctaaaacca cagccacaaa atgaaaagaa
    47941 aaaagacaag aaacaaaagt aagttaagct caaaaaaaga cttaccagcc aaacttttat
    48001 gaaagagttt gactggtaag tcttttttat tctttttatg attcaattgc ttgttcgatt
    48061 gctgcccacg cttcttcttt tccctgtttt gtaacggaag aaaagagaat aaacgtgtca
    48121 ttgcgatcaa aatccaacgc ttttttgatt tcgctctcat gcttgttcca tttaccacga
    48181 gggatcttat ctgccttagt ggcaacaaca attacaggga tatcataata cttcaaaaat
    48241 tgatacatct ggatatcttc ttgagaaggc ttatgacgca aatctactaa agaaacgacc
    48301 gcacgtagct ggtctctagt cgttaaatat gtctcgatca tctttcccca ttttgctcgc
    48361 tcagttttgg atacttttgc atacccatat cccggaacat cgacaaaatg taatgcgttc
    48421 tcgatcaaat aaaaattcaa tgtctgggtc tttcctggct taccggaagt acgggctaaa
    48481 ttctttcgat caatcaatgt gttgataaaa gaagatttcc ctacatttga tcgtcctgcc
    48541 agagctattt ctggcaattg tgtatctgga tattgttttg gtgccactgc acttatgata
    48601 atttcagctt gatggacttt catggtctct ctccttaaca aggtgatgaa taaagcaagc
    48661 ggctgtcgca aaagccaaaa tgacttttac ggcagcctct tttcatcaac ccgctttttt
    48721 ctctgaatct ttatagatta ctgttggctc accagacaat tcagctgctt cttttgtgat
    48781 aatcactttt tcgatgtttt catttgaagg gatatcaaac atcacatcca tcatgatttc
    48841 ttcaatgatg gaacgaagtc ctcgagcacc ggtattgcgt tcgattgctt ttttcgcaat
    48901 ggctctcaac gcttcaggtt cgaattcaag ttcggtatta tctagagaaa gaagtttttg
    48961 atattgtttg actagcgcat ttttcggctc agtcaagatc cgtaccagat catctgttgt
    49021 caatttctct aaagctgcca taacaggtaa tcgtccgata aactcaggga tcaatccgaa
    49081 ttttagtaaa tcttcaggaa tgatatgctg catgacactt tcgtcttcag aaagtttttg
    49141 gttttgtgta ccaaatccaa tcgtcttttc gcccatacga ttcttcacaa tcgtttcgat
    49201 gccatcaaat gcaccaccta cgatgaacaa tatgttcgtc gtatcaatct gaataaattc
    49261 ttgatgtgga tgtttacgtc cgccctgagg tggcacactt gcaacagttc cttctagaat
    49321 tttcagcaag gcttgttgga caccttcgcc ggaaacgtca cgagtaatag atacattttc
    49381 gcttttacgc gcaattttat cgatctcatc aatatagatg atcccttttt ctgcaagttc
    49441 cacattgtaa tcagcagatt gaagcaattt aagcaaaatg ttttctacat cttcccccac
    49501 ataaccagct tctgtcaaac ttgtcgcatc tgcgattgca aaaggtacat tcaatgtttt
    49561 tgctaatgtt tgtgctaaaa atgttttacc agaccctgta ggtccgatca agcagatatt
    49621 gcttttttgc agttcaacat catctgtgtt ttcttgtgct tgctgattga cacgtttata
    49681 gtgattgtat acggcaacag ctaacgagcg ttttgcgcga tcttgtccaa tcacgtagtt
    49741 attcaatact tcaagaattt ctagtggttt agggacttca gtgaattcgc gtacagcttc
    49801 ttcataaaat tcttcatcaa tgatttcttt acataggtcg atacattcat tacagatgta
    49861 gacccctgga ccagctacga tctttttcac ttcttcttgg gttttcccgc aaaaagaaca
    49921 gcgtacggtc tcattgctac ttggattgtc atacatggtc ttcacccctt aacttgcaaa
    49981 aagtatgcaa gaaactatca aagactttac agtcttttac tatcataaca tagtttagta
    50041 aaaagaaaaa gtgtttaaca aaggatcaac tgacctatac ctttgcattt tttactctta
    50101 acaaaaaata aggaactgtg acaaaatcgt gtcacagtcc cttatttcga ataaacaatt
    50161 ttctagaagt agcttcttca gaaatgattt attacttgat ttctattctt tcgcttctgt
    50221 cgctgtacct gtgatcaatt cgattgcttt tttcattgtc acatcatgtt ccagcatatc
    50281 ttctgtcaac acgcgtttga tttgttcgat tggcatgttg tatgtttctg ataattcttg
    50341 gatttctgca ttgatttctt cttctgttgc ttgaagattt tcagcagctg caattgcttc
    50401 gatcacaaga tttgttcttg tgcgcatttc tgcttcacct tcgaattgtt tatgcaagtc
    50461 ttcttctgta gaaccagtta attgatagta catttcagga gagatacctt gacgttgcat
    50521 gttgttcaag aattcgtcca ttgaacgatg tacttcatca tgaaccatca cgtgtggcaa
    50581 ttcaacgatt tctgcgtttt caacagccat acggatcgct gcttcatctt ttgcatcgtc
    50641 cgctgctttt tcttttgttt ctactaattc tttgcgatat ttttctttca attcgtctaa
    50701 tgttgatact tcgtcatcaa catcttttgc gaattcgtca tctaattcag gcacttcttt
    50761 tgcttttact tcatggattg tcactttgaa gactgcttct tttccagcaa gatcttctgc
    50821 ttgataatct tctgggaaag ttacatttac atctagactt tcacctgatt tatgaccaac
    50881 taattgatct tcaaaacctg gaatgaatga gcctgaacct aattcaagtg agtaattttc
    50941 gccttttccg ccatcaaacg cttcgccatc tacaaagcct tcgaagtcga ttactactgt
    51001 atcgccattt tcagctgcag catcttcttt gataactaat tcagcttgtg cttcttgttc
    51061 acgtttgata cgtgcatcca cgtcagcatc tgttacttca cggtcttgtt tttcaacaac
    51121 tagatcttta tattgtccta attttacttc tggtttcact gttacttcag cagtgattac
    51181 ccagtcttga cctttttcca tgctttcaac atcgattttt ggttgagaaa caggatcgat
    51241 gccagcttct ttgacagcag cttcataagc ttctggtaat acagcattca atgcatcttc
    51301 atataaagct tcttcaccgt acatacggtt gaatacttga cgagaaactt tccctttacg
    51361 gaatccaggt acgttcaagc tttttttcac tttattaaac gcagttgtta atcctttttg
    51421 gatttcgtct tgcgcaatcg taaattttaa aacaccatca ttcgtgcctt ttttttcaaa
    51481 tgttgcagtc atttaattcc ctccgagttt agaaattcat tttatacatc aaaaacgttt
    51541 catgcatacc tttaaatagt acactaaccc tttcaaattg taaacatatt gaatggatag
    51601 aatccttgtt tttcataaca tttttatctt tttcactgat aaaatctaat ggaagaagat
    51661 catttgctgc aaaatttttt ctcttttttt taaaaaatct tgtttttcat cttctgtacc
    51721 ttcatacatc gtttttcctg tacacgcctc tacagtcagt tgaaaccagc gcttcgggtc
    51781 ttcgatgtat gtatcataga caggataaac aattgcagat tgcaacgtga attcttcttt
    51841 taacacggaa ctaagcagcg catcttcatt cccgtaacga tctgaaaata cacataattg
    51901 ctggtaactt gcctgctgct gcggctttgg cagatctttt ggtatgactt tgactaactt
    51961 ttcttcaatc gtcaaataga aaacaggatg gcattcgttc aattgcctaa gtgtctccag
    52021 taattttgcc cttgctaaaa tatggacctc tggcgataca ataagtttac tcgctgtttg
    52081 gataaactca tgataaggaa gctgttcgat ctcatcaata gacgcaagct gacgtgcagg
    52141 ttccaacgaa ggaagttcct ccgatttatt gtggagtgcc ttgatcttct gcctctccat
    52201 ttgtccggat aattcttctg caaattggat tttttcaatg acccgctgct cgaaagcttc
    52261 ataaaaatct gtacttgcta tcaattttct agcatataaa aaatcttgtg tactgattaa
    52321 caagtcaaaa taaaattcag caaactcctc attttgaaga tactgttttt catgcaagag
    52381 tgcttgcttc aatgcttctt ttttctcgtc caactcgtaa agacaaaaaa caagcaggct
    52441 attagcctca aagctttctt tcaactcgta agctcgttga aataattctt ttgcctgctg
    52501 atattgctgg tttgctagtg cttgttgtgc cactcgcatt aaattctcat atttttctgg
    52561 aaaatcaatc ggcttcacgc agtgtcctcc tcttgctcat attcagctca tgttcaatag
    52621 tagcaaaaca aaaaaagcat gacaattaaa aataactgaa gcaccctcta aaagctagat
    52681 tttagatctg acttttagaa ggtgctttca actgttactg ctttttattg ctcatcagct
    52741 gttgacttcc tggttgaacg ctttgatcag attgatcgta acaacacttg tattagtgaa
    52801 aaaatcgccc agatgttgct ttttctgatt aaagactgct ggaagatacc ctaacatcag
    52861 caaaggaaat tttagaatga accggcaagc accttctcta actaaaacgg ttgaccagct
    52921 aagttcttct tcatcaaagc tgatgactcg aataccaaag atcattttcc caatcgtttg
    52981 gccatgattg aatttcgtca ataaaataaa atacgctaga taaataagta aggctgtgaa
    53041 tccgtagaga ctcagataag aatctgaaaa attaagccaa cctagatttt tggcaatacc
    53101 aagtgttaaa cgcgtaatag ctccgataca caaaagatcg accaagaagg caaacattcg
    53161 gataaaaaaa cctgcataga aatacttagg aaaatcattt gcttttggcg gttcatttct
    53221 tgtgtccgta tactttttcc atttacgttg tttctttttg atttcttcgg gcgtcaaagg
    53281 ctctctttca aaagagctca gtaccttttg ggaaaagttg gagtcaggtc ctacagcagg
    53341 ctgctgttgc ttatcttttt cttgttcctt attttcattt gaaagctctg acatgcttac
    53401 tcacctccgt aataatacat tgcttttggt gattccgctg tccctagatt ctcaagaacg
    53461 gataagatct gactagtctc agaaggcttc aatccctgga attctgctag tttacttcct
    53521 aaccatgtac tagcaaaccc agatggcgtg gaagaatatt ctactagttc cgcatcttca
    53581 agctgttgtt cctttcgtat agcttttaaa gcatcttcag gaaatcccaa ttcatcgact
    53641 aaacctactt cttttgcttg gacaccatca taaatccttc catcagcaat ttttttgact
    53701 tcttcttcag atttattccg tccctcgctg acgattgcta caaaacgact atatgcgctg
    53761 tcgatatatg cttgaagcac cgcttcttct tcttttgtct ctggtcgcgt tcctgaaccc
    53821 atatctttca acgctccgct tttaactgtt gtatcttcca cacccagttt ttctagaagt
    53881 cctgaataat tcaatcctga catgatcaca ccaattgagc cggtcactgt ttcttctgtt
    53941 gcaaagattt tatctgcttg agcagaaata tagtagccac cgctagctgc catgtttttc
    54001 atgctgacat acattgggat atcatgttct ttacgaatcg tatccaattt cttagcgatt
    54061 tccgcacttt cgtagacacc gccaccagga gaatttactt ctaaaaagat acctttgact
    54121 gttggatctt cttcaatcgc cttcagttgt tccataaaat ttttatgatt gtaaccttca
    54181 gaagcaaata aacctgaaga ccctcccgca gcaatcgttc catctactga taattttacg
    54241 attttttgcg tactgtctcc ctcttccaac acatttggag ctagttcttc atccccatat
    54301 aaccaactgt tcaatccctc aatttgatcg ttttcctgag gcttagtcaa actagctgaa
    54361 actaacgaaa ccacaaataa tcctgcagca atcagaactg ctgcccaacg tcttttattc
    54421 attctttctc ctttctaata caagtttttt atgacgatca cagtttctga ctgctcagaa
    54481 gtgtcgaacc gctctgcttt ttcttcccgc gcatacccgg aaaacgactc ttttgttaat
    54541 tcatcttcta ccgtaaactc acgagcttga gcaacttcca aggcatcagg tgcgatttct
    54601 tggatgctat cccagccagt atctaaaaat attttcgtat catctgatac accagctgat
    54661 gcttcgaatt tggacaattg tttttttaac attcccagtg tcatgatctc aatttttgaa
    54721 tccattttta ctcctcctct atccgattac tttctattgt accgaactcc tgaaaaagat
    54781 gatagataaa aacccattat tttttgacat aaaaaggaca tttgacaaag aatttgatat
    54841 ataccaattt attttttatt ctttttttgt tgacaagaac attcgcaaaa ggttatgatt
    54901 ttaaatgttt ccagataaaa aacaaaaagg aggatagtta taccttttag gatagcgcca
    54961 ggtctgtgta aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag
    55021 ggactgcact ctacagaaaa tccacaaaaa atgtctgcaa agataaaaca aaaggatttt
    55081 cctgcagctg gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg
    55141 gaattgttgg aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa
    55201 aattagaata ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt
    55261 atctggtcaa agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta
    55321 caggaaatat aggtattggt catacacgat gggcaactca cgggcaacct tctgaagaaa
    55381 acgcccatcc acatacttcc caaagtggac gcttcgtgct cgttcacaac ggcgtaatcg
    55441 aaaactttga agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg
    55501 atactgagat tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg
    55561 cgtttttaaa agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga
    55621 cagcacctga tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg
    55681 atggattcaa tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg
    55741 ttgagattga agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt
    55801 ttgcaggtga catcgtagaa cgttcttcat tcgaagcaca agtagatgct tcagatatcg
    55861 agaaaggtac ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc
    55921 gtcgtatcgc tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg
    55981 tcgatacatt gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg
    56041 cggggttagc aggtaaacag actttggaaa aattgacaca gattcctgtt gaggttcatt
    56101 tagccagtga atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct
    56161 tgagtcaaag tggcgaaaca gcagacagcc gccaagtgct ggtaaaaatc aaccgtctcg
    56221 gctacccttc acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct
    56281 ttacactgct attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg
    56341 cacaaatagc tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa
    56401 cttctcttgt attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg
    56461 tcatcgccca aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa
    56521 atgcctttta cattggacgt ggtgctgact acaacgtttc tcttgaagct gctttgaaat
    56581 tgaaagaaat cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa
    56641 cgattgcttt gatcgaagaa ggaacaccag tgatcggaat catcagtgaa gaagtgactg
    56701 gtgcgcatac tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta
    56761 ttgtctcaga gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt
    56821 atctaactac tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat
    56881 tacggggatt cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat
    56941 aaaagaacaa ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg
    57001 aaaatatctc ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat
    57061 agtaattaac tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac
    57121 cggaaggacg aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca
    57181 cttttttgat tgccggaaca tccatcgcac cgtttttatc acttacgcgg atattcacta
    57241 atttttgcgg atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt
    57301 tcatgatatt cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta
    57361 agaaaatcat gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt
    57421 ctacaacgta acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg
    57481 ctttgtggaa tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat
    57541 ttttttctgc caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc
    57601 caagttcatc caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg
    57661 ctcctttttc aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccgtcat
    57721 tgatatttaa cccgtctgga tttgtgccca ttgtataaaa atctgtttca agatcggcaa
    57781 acaaacgatt aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac
    57841 cggaaaggtc accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg
    57901 gaaattcttc tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag
    57961 catctaataa tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac
    58021 cgaaaaattt gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg
    58081 cgcttgcttt ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct
    58141 ggaacacttc gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac
    58201 ctgagattct tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct
    58261 ggcttaggac ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct
    58321 tgttggcttc accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac
    58381 tcctttaact taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc
    58441 tgatgtttct tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat
    58501 ggttgttgtc gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt
    58561 attttcttgt gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg
    58621 tgtaatctcc acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc
    58681 aattttacga gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc
    58741 accgatcgat gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact
    58801 gaaatcatag ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac
    58861 cgacttgctt ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat
    58921 acttaatact tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc
    58981 atctgtgacc atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt
    59041 gtcacctgta gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc
    59101 agatggtgtg aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt
    59161 ctcaaccgtt actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt
    59221 ttgaattttt agcggaactt catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac
    59281 gcggaacatc cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga
    59341 aagtttgaca gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga
    59401 aatcttgatc ggcacccccg taactgtttg attatacgct tcatttccag aaagcgtatt
    59461 tggaacggac tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa
    59521 actgtaaaga atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc
    59581 ataccgtcta ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatt
    59641 agttctctac gcaagattgc caaatattct tgctgggata agccagccat cagttcatta
    59701 tctaacgtga tgctgacgtc cccggtttct tcagagacaa cgatggtaat cgcgtcactg
    59761 acttcgctta taccgacagc tgcccggtgt cgagtcccga attctttagg gatcaacata
    59821 ctttctgata gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact
    59881 gcaccgtcat gcagcggtgt attaggaata aagatattga tcagcagctc cccagtgata
    59941 tctgcatcta aagcaatccc tgtctcaata tactcatcta atccagtatg acgttcgata
    60001 gtgatcaacg caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag
    60061 atcatcttct catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca
    60121 agatgttcca gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg
    60181 tacgtaatga cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg
    60241 attcggataa caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc
    60301 agcagttgga tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc
    60361 aaaaaattca gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa
    60421 agttccccga tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag
    60481 tatatcatat gttttaattt tagaggctga tatgctcgta tttttcttga gaaaaacgca
    60541 taattttcaa gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa
    60601 cttcagagaa ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt
    60661 gttccatttt tttacgtcgt tctgctctgg cagctcttct agcagctctt ctttcttctg
    60721 cttcaaggtc cgtcgttttt tcttttctag tcttaacggg tacatcgata gattcctctg
    60781 gttcaagtcg tttcttgatt ttttctaatt ctcccgtcag tgcagcatag ttgtaaaaac
    60841 gtgttttagc gtcgtggaca gtcttttcaa ataaagcttt tgcaagattt ggatttgcgt
    60901 tatctagcga ggaaaagcga acttgtttcc tcatgaaatc aggcatagca gagaaatcag
    60961 gttttttgta gtccaaagtc attgggttct tgtttttttc gaccattgta gggttatatc
    61021 gatataatga ccaataacca gaagaaacag cttcttttgc ttctttaagc gattctttca
    61081 ttccgccaag caagccatgt gtgatacaag gcgtataggc aataatcaga gaaggaccag
    61141 gatacttttc tgcttcttca aatgccttga tcgtttgcat ttgattggca cctgaagcaa
    61201 tttgcgccac ataaacattt ccatatgtca tcgccatcat tcctagatct ttctttgaag
    61261 catactttcc actagccgaa aatttagcga ttgccgaagc tggtgttgct tttgaggttt
    61321 gaccgccagt attggaatag acttcgttat ccaaaacaag gatattcacg tctgctccgc
    61381 tggcaagtac atgatcgatc ccgccaaaac caatgtcgta agcccatccg tctccaccaa
    61441 tcatccattg gctgtttttt acgaatagat cctttctctt gtatatatcc tccagttcag
    61501 ggaaaattga tcgttcgctt tcgatcgcag cttgcagttt tgctgctctt tgctgcgttc
    61561 cttcactctc aaacatgtgt actaaccagt cttccatcaa ttctcgtagt tcttctgata
    61621 cttttggcaa tacttctttg attgaacttg ccaaagcctc gcgacgagtc tgtgccgcta
    61681 gaagcatacc ataaccaaat tcagcattat cttccaataa agaatttgac catgcaggcc
    61741 cttgaccaca ttcattggtc gtataaggag aagcaggaga agcaccgccc caaatagaag
    61801 aacagcctgt cgcattcgcg atcatcattc gatcaccgaa catttgtgtc aataatttta
    61861 cataaggtgt ttcgccacag cctgagcaag cgcccgagaa ttcaagaagc ggttgattga
    61921 attgtgtaga caagacagta ttctttcctt tgactggatt tgctttttgt cttaatgtca
    61981 ttgcaaaagc ccaattcaca gcttgttctt tctgttcttc ataaggcttc atcactaaag
    62041 ctttttcttt tgcgggacaa gcctctacac acagaccaca acctgtacag tcttccactg
    62101 aaacttggat acggtatttt acgccgtctg cgcctcgcat ttctctcacg ataaatcctt
    62161 ctggcgcttc ttccatttcc tcttcatctg ctaaaaatgg acggatggca gcatgaggac
    62221 aaacaaaggc acattcatta cacatcgtac agcgatcact aatccactca ggtacttcta
    62281 aagcgacgcc ccgcttttcc atagaagccg ttcctaaagg catttcgcca gttgtcattc
    62341 catttgctac aagtgtacca acagagagtt gatttccttc ctgtgcattc actggttcaa
    62401 gtatttcttg tatataacca gtgttccttt tattgatttt ttcaggcatc tccaacgttc
    62461 tccaatggtc tgggatcgcg acttgatgaa gcagttcggt cgtccgatcg attgcttgta
    62521 tgtttttttc tacgatagcc attgatttat gtccatagct tttcagggct tcttctttta
    62581 gcagcggaag cacctcatca aaaggaatga tgtcagctaa tttaaaaaaa gccgtttcca
    62641 ttgccgtatt gatccggcgt cccaaaccga cttcttgggc caatctcatg gcattgatcg
    62701 tatagaatct aatgttattt tcagccaagt aacgttttaa ttttaagggc agatgcgttt
    62761 ctaattgttc gtcgctccaa agagtattca ataaaaaaat gccacctggc ttcaatcctt
    62821 tgaccaagtc atagctatgc aggtaagctg gtgtgtgaca ggcaacaagg tccgcatgct
    62881 cgacaagata cgctgaacgt atcggcgtat ctccaaaacg aagatgagag acagtcagac
    62941 cgccagattt tttcgaatca taataaaaat agccttgcgc atatttatcg gtgtgatctc
    63001 caataatctt gatagctgat ttatttgctc caactgttcc gtcagatcca aatccccaaa
    63061 acttggcctg gaatgtttgc ggttctgtca aatccagact ttcctttggt tccaaagatt
    63121 gataagtcac atcatccacg atccctatgg taaaccgttt tttgcgtatg cttgggtctt
    63181 ttttcaattc atcaaaaact gctgagattt ggtcgggagt cacatcttta gaccccaatc
    63241 cgtagcgacc accaataaca gccgggcgaa gttcagaatc atataacgca ctttgaacgt
    63301 ctaataagag aggttctcca cctgcccctg gttctttact tcgatcaaga acagcaattg
    63361 tttttactgt atgaggcaac ttttgcacga atgtttccac tggaaaagga cgataaagat
    63421 ggatattcaa aaaacctgtt ttccgtccgt ttgcattcaa gtaatcaatc gtttgttcaa
    63481 tcgtctgtgc aactgatccc atagaaacaa tgacttcttc cgcatcgtct gctccgtaat
    63541 aagtcaccaa gtcataagaa gttcctcgta atcggttgat ctctttcata tatttttgaa
    63601 cgatttcagg taatttatca taataggggt tgatcgtttc ccgttgttga aaatggatgt
    63661 ctggattctg gttcgtacca ctaacagtcg gatgattggg attcatccct cgtttacgaa
    63721 atgaagctaa tttctcctga ttgatcagag gagctaattc ttcatattcc aaaacttcga
    63781 ttttttgaat ctcgtgactc gtacggaatc catcaaagaa attcaaaaaa gggacttctc
    63841 cttcaataga agcaagatgg gcaacaggtg ctaaatccat cacttcttgt acactgcttt
    63901 cagctaacat agcaaatcct gtttgtcttg cagccatcac gtctccgtga tctccgaaaa
    63961 tattcaacgc atttgtcgtc actgcccgac tagcaacgtg gaaaacactt ggcagtagtt
    64021 ccccagcaat cttgtacata ttcggtatca tcaaaagcag cccttgtgaa gcggtatatg
    64081 tagttgtcag tgcaccagtt ttcaatgatc catggaccac accagctgct cctgcttcgg
    64141 attgcatttc tactactttt actggttgac cgaatacgtt ttcttttcct gctgctgacc
    64201 attgatctac taattcagcc atggtcgaac tgggtgttat tggatatatt gcagcaatct
    64261 cggtaaatgc ataagaaata tatgcggctg ccgtattgcc atccattgtt ttcatttttc
    64321 gcatgattca tcatccttgt tcatattctc tcttattatc tgttccatta taacgtaaaa
    64381 catgccattt ttttctttta tttataaaaa tattttacat gtatctattt gaattggtca
    64441 tctaattttt agacaaacag tctaaatcgt tgcctttttt tgtcagacat gtataaacta
    64501 taagcgaaag aggtgtttta acatggatat atcagtgatt gatgcaacga aaacaaatac
    64561 acaaaaagga atcctttatg gttcatcgaa tgctcctaaa aaaatggtcg aattcatcaa
    64621 cttagcttgt ccgtattgcc gacaatggtt tgaagaatct tatgagctat tagaagaagc
    64681 agtccaaagc gggcaattgc agcgagtgat caaattgttc gataaagaaa aagaaagctt
    64741 acagcgaggg aacgtgatgc accggtatct cacaatcagc gatggccaaa aagcgatcaa
    64801 agagatcaaa caaatattcg atactcaaga cgagtggaaa catctttctc tccaagaagt
    64861 agcggatttt gcagtagata aactaaagct gacagaacaa aaagacgaac agctgagcca
    64921 agctgtcatc aacgaagctg agcaagcaca tattcgattt gttccaactg tcatcttggg
    64981 taaagaaatc tttgatgaat ctatttcaat agaggaatta aaagaattga tccaaacaaa
    65041 ataaaaaaat aaggagcgtg ggacaaaagt aaagaacact tttgtctcac gctctaaaca
    65101 cgtataaacg gcggaagcag aagcaactcc ttcttatttc ttggagttaa acgcttctgt
    65161 cccagcctcc ttattccgaa taaatggtgt ccaaaagctt gcatctgcca gattatctca
    65221 tttcttatga caagctaagc aaattatctc caccaaataa tttattcata tttttgactt
    65281 gcgcatacta actaattctt aaattttcat acaaaatttc tcaatttccc ttaacgagta
    65341 atatttatgt acggtgattc tcactagtat cccaatcact ttttaagtta tcccgatttc
    65401 aattctactt caaaaatagt tgcttttatg tatgctgtta gttgattaga tggtcatttg
    65461 ttgagctagg tcgtttattt taaacaagtt gtttctttag cttataccta tctcgtctac
    65521 caaacgcaag atggcaaaca caaatgcata cgcatctgta tt
//
LOCUS       DARPZF010000011        59527 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.011, whole genome shotgun sequence.
ACCESSION   DARPZF010000011 DARPZF010000000
VERSION     DARPZF010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.011"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(341..1651)
                     /locus_tag="SLE65_000977"
     CDS             complement(341..1651)
                     /locus_tag="SLE65_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HEI8448286.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1663..3081)
                     /locus_tag="SLE65_000978"
     CDS             complement(1663..3081)
                     /locus_tag="SLE65_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8448287.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3321..4889)
                     /locus_tag="SLE65_000979"
     CDS             complement(3321..4889)
                     /locus_tag="SLE65_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HEI8448288.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4893..5303)
                     /locus_tag="SLE65_000980"
     CDS             complement(4893..5303)
                     /locus_tag="SLE65_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HEI8448289.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5300..6223)
                     /locus_tag="SLE65_000981"
     CDS             complement(5300..6223)
                     /locus_tag="SLE65_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HEI8448290.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6220..7098)
                     /locus_tag="SLE65_000982"
     CDS             complement(6220..7098)
                     /locus_tag="SLE65_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HEI8448291.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7085..8422)
                     /locus_tag="SLE65_000983"
     CDS             complement(7085..8422)
                     /locus_tag="SLE65_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HEI8448292.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8425..9528)
                     /locus_tag="SLE65_000984"
     CDS             complement(8425..9528)
                     /locus_tag="SLE65_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEI8448293.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9602..11110)
                     /locus_tag="SLE65_000985"
     CDS             complement(9602..11110)
                     /locus_tag="SLE65_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEI8448294.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11076..11768)
                     /locus_tag="SLE65_000986"
     CDS             complement(11076..11768)
                     /locus_tag="SLE65_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEI8448295.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11790..12764)
                     /locus_tag="SLE65_000987"
     CDS             complement(11790..12764)
                     /locus_tag="SLE65_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8448296.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13064..13936
                     /locus_tag="SLE65_000988"
     CDS             13064..13936
                     /locus_tag="SLE65_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEI8448297.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14394..16592)
                     /locus_tag="SLE65_000989"
     CDS             complement(14394..16592)
                     /locus_tag="SLE65_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8448298.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16824..17816
                     /locus_tag="SLE65_000990"
     CDS             16824..17816
                     /locus_tag="SLE65_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8448299.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17876..19297
                     /locus_tag="SLE65_000991"
     CDS             17876..19297
                     /locus_tag="SLE65_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HEI8448300.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19290..20789
                     /locus_tag="SLE65_000992"
     CDS             19290..20789
                     /locus_tag="SLE65_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HEI8448301.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20828..22222
                     /gene="uxaC"
                     /locus_tag="SLE65_000993"
     CDS             20828..22222
                     /gene="uxaC"
                     /locus_tag="SLE65_000993"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEI8448302.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22381..23064
                     /locus_tag="SLE65_000994"
     CDS             22381..23064
                     /locus_tag="SLE65_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HEI8448303.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23066..23902
                     /locus_tag="SLE65_000995"
     CDS             23066..23902
                     /locus_tag="SLE65_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HEI8448304.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            23913..25667
                     /locus_tag="SLE65_000996"
     CDS             23913..25667
                     /locus_tag="SLE65_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8448305.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(25943..26284)
                     /locus_tag="SLE65_000997"
     CDS             complement(25943..26284)
                     /locus_tag="SLE65_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEI8448306.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26352..28523)
                     /locus_tag="SLE65_000998"
     CDS             complement(26352..28523)
                     /locus_tag="SLE65_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEI8448307.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGATETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28692..29591
                     /locus_tag="SLE65_000999"
     CDS             28692..29591
                     /locus_tag="SLE65_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEI8448308.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29662..30519)
                     /locus_tag="SLE65_001000"
     CDS             complement(29662..30519)
                     /locus_tag="SLE65_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEI8448309.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30504..33206)
                     /locus_tag="SLE65_001001"
     CDS             complement(30504..33206)
                     /locus_tag="SLE65_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEI8448310.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33219..34508)
                     /locus_tag="SLE65_001002"
     CDS             complement(33219..34508)
                     /locus_tag="SLE65_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEI8448311.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34658..35704
                     /locus_tag="SLE65_001003"
     CDS             34658..35704
                     /locus_tag="SLE65_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8448312.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35706..37859
                     /locus_tag="SLE65_001004"
     CDS             35706..37859
                     /locus_tag="SLE65_001004"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEI8448313.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38332..39783)
                     /locus_tag="SLE65_001005"
     CDS             complement(38332..39783)
                     /locus_tag="SLE65_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8448314.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39780..41504)
                     /locus_tag="SLE65_001006"
     CDS             complement(39780..41504)
                     /locus_tag="SLE65_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEI8448315.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41497..42111)
                     /locus_tag="SLE65_001007"
     CDS             complement(41497..42111)
                     /locus_tag="SLE65_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEI8448316.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42456..43913)
                     /locus_tag="SLE65_001008"
     CDS             complement(42456..43913)
                     /locus_tag="SLE65_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEI8448317.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(43954..44874)
                     /locus_tag="SLE65_001009"
     CDS             complement(43954..44874)
                     /locus_tag="SLE65_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEI8448318.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44886..45833)
                     /locus_tag="SLE65_001010"
     CDS             complement(44886..45833)
                     /locus_tag="SLE65_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8448319.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46312..47031)
                     /locus_tag="SLE65_001011"
     CDS             complement(46312..47031)
                     /locus_tag="SLE65_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEI8448320.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47080..48726)
                     /locus_tag="SLE65_001012"
     CDS             complement(47080..48726)
                     /locus_tag="SLE65_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEI8448321.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            48905..49495
                     /locus_tag="SLE65_001013"
     CDS             48905..49495
                     /locus_tag="SLE65_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEI8448322.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49587..51092
                     /locus_tag="SLE65_001014"
     CDS             49587..51092
                     /locus_tag="SLE65_001014"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEI8448323.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51176..52528)
                     /gene="celB"
                     /locus_tag="SLE65_001015"
     CDS             complement(51176..52528)
                     /gene="celB"
                     /locus_tag="SLE65_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEI8448324.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52528..53046)
                     /locus_tag="SLE65_001016"
     CDS             complement(52528..53046)
                     /locus_tag="SLE65_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448325.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53062..53388)
                     /locus_tag="SLE65_001017"
     CDS             complement(53062..53388)
                     /locus_tag="SLE65_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEI8448326.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53401..55380)
                     /locus_tag="SLE65_001018"
     CDS             complement(53401..55380)
                     /locus_tag="SLE65_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEI8448327.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55401..55715)
                     /locus_tag="SLE65_001019"
     CDS             complement(55401..55715)
                     /locus_tag="SLE65_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEI8448328.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55883..56176
                     /locus_tag="SLE65_001020"
     CDS             55883..56176
                     /locus_tag="SLE65_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEI8448329.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56254..57366)
                     /locus_tag="SLE65_001021"
     CDS             complement(56254..57366)
                     /locus_tag="SLE65_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEI8448330.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57519..57743
                     /locus_tag="SLE65_001022"
     CDS             57519..57743
                     /locus_tag="SLE65_001022"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448331.1"
                     /translation="MNGSIKKILRSIDKNLMITEVSYETLQKKKTLIVAAVLFPAPCV
                     CRNCGSAVVDGNRKLMVVKNKKKETIVHFE"
     gene            57753..57932
                     /locus_tag="SLE65_001023"
     CDS             57753..57932
                     /locus_tag="SLE65_001023"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448332.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58126..58296
                     /locus_tag="SLE65_001024"
     CDS             58126..58296
                     /locus_tag="SLE65_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8448333.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(58720..59460)
                     /locus_tag="SLE65_001025"
     CDS             complement(58720..59460)
                     /locus_tag="SLE65_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEI8448334.1"
                     /translation="MTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGL
                     TTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTP
                     GGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVET
                     QAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGE
                     TIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT        17804 a        12168 c        10405 g        19150 t
ORIGIN      
        1 agcaactttt atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt
       61 ttcgatttcg tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat
      121 ttgtcaagaa cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt
      181 taacgactta gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc
      241 ataaaatgtt tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg
      301 tcaagctaaa atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat
      361 tgtttgcagc tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt
      421 gtactgcttc gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat
      481 cttctatagg cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac
      541 ctggagaaag gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct
      601 ttgattcagg tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat
      661 tgctattttt tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta
      721 catcaatcat attcagattt tctaccctga tattttcgat cactccccct ctttcttttg
      781 aagatttcat tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt
      841 cactaactcc agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac
      901 atctagcaac ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc
      961 cagacttaat agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat
     1021 ttgttgaaga atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta
     1081 ctttttctac taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct
     1141 gaaaaatcaa atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac
     1201 gtttaatagc ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc
     1261 cgcttttttg atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta
     1321 ttccttttcc ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc
     1381 atttcatttc tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc
     1441 tccccttgag gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg
     1501 ctccgactaa ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat
     1561 cgattgcttt ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca
     1621 aagcattgat aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt
     1681 tttcaattct tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa
     1741 aatgattgcg gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct
     1801 ttcttgtact aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag
     1861 tgccagcata aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga
     1921 atttactcca tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat
     1981 cacgtcagta atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat
     2041 aaataaaaga atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta
     2101 catacatgaa gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt
     2161 cagctttgta gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac
     2221 agacattgct tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc
     2281 taaaatctga ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt
     2341 agctaacaaa ccttttacca actgagaagc agatactttt tcgtttttga caactcttac
     2401 tctttcagta gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc
     2461 gattgaaatc caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt
     2521 atacattaaa atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct
     2581 tcggaacgtg gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc
     2641 tccatacggg atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat
     2701 ataagcaatc ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt
     2761 cactaagcaa aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt
     2821 taactctgag acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct
     2881 cgaaatcaag aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata
     2941 aatcatcaag aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat
     3001 gtagcctatc ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt
     3061 aacagcattt tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa
     3121 ttataactct ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt
     3181 gacagataaa aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt
     3241 tacataacaa tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc
     3301 tcatttatta aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa
     3361 tcagcataac ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca
     3421 gtaaaccctc ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca
     3481 gttgatacgt ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa
     3541 gtcttctttt ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat
     3601 tctatcatac gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa
     3661 ttggattcat ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat
     3721 tcaaatgctg tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt
     3781 tcgaaggtag attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt
     3841 gtatcacacc aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct
     3901 ccttcaaatg tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca
     3961 atcattattt cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac
     4021 gtccaataca cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt
     4081 ctggtacaaa gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt
     4141 cctgtacatt gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga
     4201 tcaagctcgt aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt
     4261 cctgtaccgc cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt
     4321 gcctccgttt tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc
     4381 ttcttctctg catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga
     4441 cgataatccc atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa
     4501 gaaggatcaa agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca
     4561 gatgcagtga tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct
     4621 gtgtaaacaa gataaaacaa tccatcagca taactgatct gtggcgccca tatacttcca
     4681 tttgtaggat ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag
     4741 ttgactaaat ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca
     4801 ataatgtaat accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa
     4861 ataggatttt tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga
     4921 tataaactga atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga
     4981 gtgccaatca acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat
     5041 tttcctttag cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca
     5101 acggcaaaca gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt
     5161 gaatgatcta cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt
     5221 aaagtaactg ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc
     5281 aatagttccc attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag
     5341 gtcttttgat cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat
     5401 ttttcttgtc atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg
     5461 cttcaaataa gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat
     5521 caggttctgc agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg
     5581 tagatgctgc tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat
     5641 gaaaaacggc atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt
     5701 cataggtctg acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat
     5761 ctttttgcaa atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac
     5821 agttttttaa agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt
     5881 ctcctggacc tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta
     5941 agaaaaaagt agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg
     6001 caaaacgatt accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc
     6061 tgctttctat atattcatca tatcttcctt cttttactat caagaccttt ggatggctat
     6121 ccggcaggcc tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat
     6181 ctatagcatt ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa
     6241 ttgtttccaa atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga
     6301 agaaaagttt tctggactac ccattgattg atactttttg tccagccctt ttctcagctt
     6361 cagtacgcct tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg
     6421 cggagcgatt ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata
     6481 gtaataaaac ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg
     6541 tgccgctaga tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa
     6601 taagcctccc atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt
     6661 ctccaaataa tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc
     6721 tgttaataaa aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc
     6781 ccaagcatca atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg
     6841 agaagctaag taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc
     6901 gtgagaatgc aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag
     6961 ggctggtact gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt
     7021 ttgtttttct cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa
     7081 aaaatcattc aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg
     7141 attgatttga ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg
     7201 gtccctcgtg attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat
     7261 aaaatccttg tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg
     7321 catcttgggc catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg
     7381 ctaatccata aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat
     7441 ggatccttct gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat
     7501 acggttcttt ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca
     7561 cattatccat gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc
     7621 tagatttcaa tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat
     7681 tacgaatact accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg
     7741 tgcaatttgt gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg
     7801 ccttgattgc aatacagtca tctcccacgt caatatggca attactaata cgcacatttt
     7861 tgcatgattc tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca
     7921 agttatcaaa cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga
     7981 tcaatttaat atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac
     8041 gaggataagc gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc
     8101 catctaatgt accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg
     8161 aagcataaac ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg
     8221 gatcgtcaga gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta
     8281 aaaataaagc tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac
     8341 ttgctgcagc atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc
     8401 caaatgtcaa aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa
     8461 tgcaccaacg cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga
     8521 accatctcgc tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag
     8581 ccagccttct tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac
     8641 ttgtggaagc cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta
     8701 aacaaacata ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt
     8761 tacttgatac catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt
     8821 ttctagaatt tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc
     8881 tgctgcagcc atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt
     8941 ttttggatca gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt
     9001 ttttggatcg aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc
     9061 tttttcttca ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc
     9121 atccaaccaa atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg
     9181 tggatggttt gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc
     9241 tgtttctttg tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc
     9301 ttcaacgctg tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt
     9361 tatgaaatca aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag
     9421 tacgacgcca tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg
     9481 tgttctttcc atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc
     9541 tttaaaaatt aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat
     9601 attactgtgc cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt
     9661 gtgctttcca gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt
     9721 attgcaccgt agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg
     9781 gtgaatccaa tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt
     9841 gattagagaa ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac
     9901 gagagcttga taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag
     9961 aaccatcatc attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca
    10021 catcttcttc taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt
    10081 ttacttgaga tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat
    10141 gataaccgcc gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt
    10201 gaataccttg acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag
    10261 ttcttccttg tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg
    10321 ccaaatagcc attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg
    10381 tatcaaattc tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa
    10441 aataagaagt gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa
    10501 aaccaactgt gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta
    10561 cttcataaag ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt
    10621 ttcgaatgac taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac
    10681 cgtcgatact cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt
    10741 ttaaatattc tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt
    10801 ttttcaacat cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag
    10861 ttgttaatct ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg
    10921 ttttttcttc gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat
    10981 ttaaccaagt gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc
    11041 tgccgcatgc ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg
    11101 cttttttcat aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt
    11161 tctgtatatg agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact
    11221 gcggaaaaga agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc
    11281 atcagataaa tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat
    11341 ccgaataaaa atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg
    11401 attgggaaaa tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc
    11461 ctaagatacc aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca
    11521 tatatccagc tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt
    11581 ttcgtcaaag gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca
    11641 tacgatgcag gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga
    11701 aaattcaaat aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac
    11761 tgcagcatat ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg
    11821 gcaatcttat tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt
    11881 gctgtactga aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa
    11941 atttctgcaa cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag
    12001 tctaatgtct gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc
    12061 aatgtaacat gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac
    12121 aactgtgtat cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct
    12181 ttccagatca cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg
    12241 attttttcaa atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa
    12301 aatacataag taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc
    12361 gtttgaatcc cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg
    12421 attggcatcg gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat
    12481 aatgtaaaga atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga
    12541 cttcccatta ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata
    12601 ggaagatacc taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat
    12661 ttattcgttt tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc
    12721 gatagcgtca gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt
    12781 ttgtgaatgt ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat
    12841 catttttacc gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat
    12901 aaagtgtatt ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga
    12961 cacttagcat aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata
    13021 gaaacagaaa catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc
    13081 tataggagaa agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat
    13141 ctgtatcgtt ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt
    13201 cgcgaaaaag tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct
    13261 ttctacgccg accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac
    13321 gatcgtcagt atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt
    13381 tggtcgaggt ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat
    13441 tccaacgttc ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct
    13501 gcctgtggct gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc
    13561 ggatagtttg gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa
    13621 aattatgctg ccattagcgt taccgtctat tgctactatc tcgctttttt atgctgttac
    13681 ttactggaac acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat
    13741 acagattctt ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc
    13801 cgttgatgtg attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt
    13861 gcctatgctg attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg
    13921 ttctgtcaaa gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag
    13981 cttcaagaaa taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc
    14041 ttatttttcg aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt
    14101 cagccttgag cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa
    14161 taagaagcga ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat
    14221 agcctgtctc ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca
    14281 gttctttttg cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta
    14341 ttctaacttc ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattcacaaa
    14401 tatttttttc gatattctcc cggcgtaatc gattccttct ttttaaagaa acgaataaaa
    14461 ttttgcggat ttcgatattg caatctttct gcaatctctt ttacggagag gttagtctct
    14521 ttcaaccatt tttttgctac ctctaaacga tgattttgaa caaaatcacc aaatttttct
    14581 cctgtttcct ttttaaatac attacttaaa tagttagggt tataatgcaa cctatcagcg
    14641 atcacatcta aagacagatc acgatcatat tctgtgtaga cgatatgcat aatattctcc
    14701 gacaaatttt taaattcatg atcagtgatt gcttgagagc attctgtgat tggcagaact
    14761 aattgttcta aaacaagttt ttctagttct ttgggatgat aattgttcag tgcttttaca
    14821 taaatttgtt tcatgttatc aaagtttttt gaatctactc ccaataactg tcctaattga
    14881 acgagttcat tgatcaagcg gaccgaaact acttcccgac tcaaaggatt tttattttgt
    14941 gcaaacaatg catcaatcaa ttcatgtact aaattcttca cttcctgatt tccagaacga
    15001 atggcttcaa acaatcgatt ttgttcttct atcggatatc taataagtgt tttttcatga
    15061 gcagcaggaa cgatttcctg ataaaaaata attgaacttg gaccagtatt tacacgataa
    15121 tacagggctt cttttgcccg atcaaccgat tgcttgcttt cattcagcgt ttcgaaccgg
    15181 ttactgatgc ctatactgat agttaaattc aagtattctt ttacacgttt ttgaatgagt
    15241 cggcaatact ccatgacttt tttgcttgct tctgcatcat ctttatccat tcgataaata
    15301 gtggcttgca tttcttcatt caaaacgatc ggcagcattc gattttcctt tggcacaatt
    15361 tccgtgatca tgttgttgat cgctaaaagt agcaaatcac gctccccacc gtgactatct
    15421 tctaacagat cgatttgaac caaagctgta taatagcagt cattttgaga actataacca
    15481 aattgctgca accgctgatc tagttctcgc ctttctactc gatttctaaa taaactaagt
    15541 acaaatagcg tttccagctg tggcttttgg gtaactaagt gtgcacttaa cgcttctttt
    15601 tctcctatga tccgactgac tgattgagcg accaaatcta gttctttccc actgaatcct
    15661 tttgatttaa gattcagacg ttcctgtatt tgagaaatcg gacgggcaaa tctgtccgaa
    15721 aataagtagg aaagaagacc aatgagtcct accagtgtta aagacactgc aactagcccg
    15781 attctcagat tgcggatcat tgcgccaatt gcactagagt caacttctaa tctgtaaatc
    15841 caattattat aatctgattt cagtactata tacgttttat ctttttctct tatcactttc
    15901 agctgattgt aatctagatc cacgtccgtt aatacagttg gttgctcttt attttttact
    15961 gtctgagtag taaaaaggtt gccaacttcg ttttcaatag aaagtatgtc ttctccactt
    16021 tcaccaacaa cttgttctat tgtatgtttc tctatcgtag caattcccaa tgcatatttt
    16081 tctttttcaa acattggcaa agaaatcacc atttcgattc ctttgttttt cttttgccaa
    16141 aataaattat ttttgttatt tatgtacttc tgttgatact tttcaatttc ctcttcggtc
    16201 agttgactca acgatccatt gattactccc catttaccag ccaaactgac taaatcataa
    16261 ttattatcat ccataacaat cgtttctata aaatttagtt ctttcctgat ttcagaataa
    16321 gtggagtaat ctgtatatgt cagcggatgc ttgaatatgt ccgagaaatt tttggtcgaa
    16381 ccatacgtag aaaacgaata ttcaatcgtt ctaattttcc attcaacgtt agttttaact
    16441 tgcctgagca aattcttttt gtctgttaaa taactcgatt cgatcgattc ataggtattc
    16501 tggtaaatga ataaactaaa tcctatgaca agtacggctc ctaataaaaa catcggtaaa
    16561 aatattttat aaaatactgt acttttcttc attttcttcc tctcctcctt ttaaaataaa
    16621 aggctttcat ttttctgtaa aattgatact catctaatta aatgagcatt ccccgctttc
    16681 aagaatagca taattaaaaa taaaaatcca agtaattttt aacgtgtgca atcttttcat
    16741 atcaaagatc tattgactta tcgtagttat cgtaatatga tgaatgcgtt aacaaaaagt
    16801 gaaaaagtaa ggaaaatgat ggaatggtaa cgatcaaaga tgtcgctaaa gcagctggcg
    16861 tttctcatac gacagtttct cgtgctttga ataacagcag tttaataaaa aatgaaacaa
    16921 aacaaaaaat acgacaacta gctaaggaaa tgaattattc gccaaactat agtgcaaaag
    16981 gtttagtgaa tcaaaaaaaa tatctaatcg gactattttt ctcaagtttg cataaaggaa
    17041 cttcatcaaa tttcctagca gattccattg caggcatcca ttcagtatta gacacaaatt
    17101 acagtttatc tgttgaaagt atcgatgttg ttgatttaac agaaatcaac ctgcaacgct
    17161 acgatggact gatcgttatg agtcaaagtg atgatgatca gcctttcatc gactatctca
    17221 aagaaaaaga atttcctttc gttgttgtca atcgtcacat caatgatcca gcggttatca
    17281 acgtcactgc cgatgatgcg gccggtgtta tgcaggcagt agattacggt attggatgcg
    17341 gacatacgaa gatcgcttat attggcggaa agaaaaattt tcgttcgaca aaagaacggg
    17401 aaaaaggggt attgaaaagt ctaaaaaaag cgagcatccc tgtcaatcca gcctattttt
    17461 taacaggaga ttacagctta gaaagcggcc tccaaaacat ggaataccta ttatcacttt
    17521 ctgacctgcc tactctggtt ttttgcggca acgacgacat agcgattggt gcattgagag
    17581 ctgtacattt agctggcctc cgtgttcccc agaacatttc tctgatcggg ttcgatgatt
    17641 ctccagtcgt ctcctatctc aatccgccgc ttaccaccgt acgtaagcct ttgaaagaaa
    17701 tgtgtcaaga aggaacaaag cttttactag atttgatcga aggcaggacg atcgaacaat
    17761 ctaaaattga gctctccacc ttgttgatcc ttcgtgagtc gatcaattac ttgtaaacta
    17821 caagtaattt tatataaaaa tgttaacgtg tgcataacac agaaaggaag tttatatgaa
    17881 aaaactgaca aaagaattag tgaaaaaaaa cgaagcacct gtaaaagttc ttcagtttgg
    17941 tgaaggcaat tttatgcgtg gatttattga ttggcagatt cagcagctga ataaccaaca
    18001 attgtttaaa ggtaatgttg caatcattca acctttagaa caaggtcttg gaaatatgat
    18061 gaaccagcaa gataatttat atacggtcat tttacaagga ctcagcaatg gcgaaatcgt
    18121 tgatacttcc gagattatca ccgtagtaga acaaatgatc aatccttatg atgaatggga
    18181 tgcttatcta tctctagcag aaaatgacga cttggcctat atcgtctcca atacaacaga
    18241 ggcaggaatc caattcgtgg agactgataa tttaacagat actcccccac agagcctccc
    18301 gggcaaactg acagcctttt tataccgacg tttcaaatta aacaaagctg gctttaccat
    18361 cattccttgc gaactgattg acagaaacgg cgaacgtcta aaagaaatca ttttacgcta
    18421 cgcagaaaaa tgggatttag aacctgcttt tgttgagtgg ttagaaaaag aaaatgtttt
    18481 ctgttgtagt ttagttgatc gcatcgtccc aggttatcct cgcgaagatg caggtgtttt
    18541 caatcaacgg cataactatg aagatcaatt gatggtcaaa gcagaaccat tcatgctttg
    18601 ggtgatcgaa gggcctaaag aattggagaa tcaactacca ttcaaacagg ctggcttgaa
    18661 tgtcatcatc acagatgata tgactcctta tcgtgaacgt aaggtgcatt tgcttaatgg
    18721 accgcataca gcgatggtcc ctcttgcttt gttggcggaa ttggaaactg tagaagaagt
    18781 aatgaaagat cctttattct ccgcatatgt tgatcagtta ttcaatctag aattgattcc
    18841 tatgctttct ttacctaaag atgaattagc catttatgct gaccaaatca aagaacgttt
    18901 cttgaatcct tttgcccatc acaaattaga agcgatttca ttaaatagtg tttcaaagtt
    18961 cagcacccgt ctgcttccag tgttcaagaa gtatatcgaa gaacaaaatc aggtaccacc
    19021 gttaatcact gtttcactag ctgcgctact tcttatgtat cgaggcgatc aagtaaagcc
    19081 acatgatgat gaaaagacga taagcgaatt tactgatgct tggtctgata atggaacagc
    19141 tattcctcga ttattgcaaa acgctgcgct ttggggagaa gatttgtctc aaataccgaa
    19201 tgtgacagat acagttcaag aaatagctgc aaagatcgat caaaaaggtg tccggtcagt
    19261 attacaagaa atgaaaggaa cgatggtcca tgcttgaaac cctgcaacca acaatgaaat
    19321 taaatcgacg agacagtgtg gtcgtcgcat taacccctat tccaaaacaa acacaactga
    19381 cgattgatca gcaaacgatc accactcttg aagatatccc gcaaggtcat aagattgcat
    19441 tgggtgattt gaaagctgga gacaacgtga tcaaatatgg ctatccaatc ggtcatgtga
    19501 cgacagacgt aactgccggt caatggctgc acactcataa tgtaaaaacc aatctttctg
    19561 gtgaattgga ttatcgatat gaaaaagatg tccatccaag tcattacctt tttgagaacc
    19621 gaacatttca aggttacttg cgaaaaaatg gaaaagtagg gattcgtaat gatttgtttt
    19681 tagtacctac cgttgggtgt gtgaatggca ttgctgaact gatcgtcaaa cagttcaagg
    19741 aaaaacatcc agatctggga cagtttgacc atattacgat tttaaagcat ccttatggct
    19801 gttcgcagct tggaaaagat catcaaaata ctcgagaaat tttagcggac gcagtaaatc
    19861 atcccaatgc cggaggagtt ttagtatttg gattaggttg tgagaacaat acagttcctg
    19921 aattcaaaaa aattttaggt gaatatgatg aagaacgagt gaaatttcta gtggctcaag
    19981 atgtttacga tgagatcgaa caaggtgtgg ctctattaga agagctttta acagcggcgg
    20041 aaaatgacca gcgcatatca gtcccgctct ctaagttgaa tgtcggtttg aaatgcggcg
    20101 gttctgatgg tctatcggga ataactgcta atcctttact tggtgcattt tctgactact
    20161 tgattgctca aggaggcagc acgatcttaa cagaagtgcc agaaatgttt ggcgcagaac
    20221 aagtattgat ggcacgagcg gaaaatgaag aagtttttga ctcaatcgtt gacttgatca
    20281 atgacttcaa acagtatttc ttgtcttacg gggaaccagt ttacgaaaac ccatctcctg
    20341 gtaataaagc aggtgggatc actacattag aagataagtc tttaggctgc acgcaaaaat
    20401 caggaagctc tcctgtcgtt gatgtgctac aatatggcga aaaaatcaga aaaccagggc
    20461 ttagtttatt gcaagctccc gggaatgatc ttgtagctgc ctctgctctt gcttcatccg
    20521 attgccagtt ggtcttgttt accacaggaa gagggactcc gtttggctca tatgtcccaa
    20581 cggtcaaggt atctacgaat acaactcttt ttgaacgcaa aggtcattgg atggatttta
    20641 atgcaggcgt cttattagaa caaccaatgg aagtaatctt agaatcgttt gttcaaaaaa
    20701 tcatcgctgt agctagtgga gaagaaacga aaaatgaaca aaatgacgtt cgagaaattg
    20761 ccatttttaa aaacggagta acactttgat tttcataaaa cagtataaaa agaaagaagg
    20821 aagatttatg tttttatctg atgatttttt attaaaagac gattgggcga aaaagcttta
    20881 ccattcctac gcaaaaaaca tgcccattat tgattatcac tgtcacttag atccaaaaga
    20941 aatttacgaa aacaacaatt tcagcaatct gacagaagct tggttaggag gcgatcatta
    21001 caaatggcgc ttgatgcgag cttgcggcgt gcctgaagaa aaaatcacag gaaatgcttc
    21061 tgattttgaa aaatttttag cttggtgtca aaccgtacca aaaattatcg gaaatccgct
    21121 ttacagttgg tcacatcttg aattgaagcg tttcttcggt attgacttgt tgataaatga
    21181 agaaaatgca gagaaaattt ggacacaagc aaatgaaatt ttggcagctc ctgattttcg
    21241 ccgtcgggaa atcgcaaaaa aatcgaatgt agaagtgatt tgtacaacag atgatcccgc
    21301 agacgacttg cactatcatc agttgcttgc tcatgaagaa ccagatttga aggttctacc
    21361 ttcattccgt ccagataaag cactcaatat tgaaaaagaa ggatttaatg catgggtcac
    21421 actactggaa gaagcagctg accaaacgat caccacctat caagaactga tagaagtctt
    21481 agggcagcgg atagaatact tccatcaaca tggatgtcgt gtttccgacc acgctttaga
    21541 catcttacgc tataaagaag cggatgaaac agtattagaa gagatttttc aaaaagcacg
    21601 agctaacaaa ctattatctt cagatgaaat cgatgcttat cgtacagaaa cactgataca
    21661 tttgacccac ttctatcatt ctcataattg gacgatgcag ctgcacatcc atgcttatcg
    21721 taactgtaat acacaaatgt tggaaaaatt agggcccgat accggctatg atggaatgaa
    21781 tgatctttct ttgactattc ctctgcaaaa attattgaac cgtgcagaag aaacggatca
    21841 gttgccaaag acgatccttt attcattgaa tccgaatgac tatcctgcga ttttagcttt
    21901 gatgggctgt ttccaaaaag aacagaatgg aaaactgcag ttaggttctg gatggtggta
    21961 caacgatact cgagctggta tgcgcgatca attgacacaa tttgctgatg gtagtgcttt
    22021 ggggaatttt gtcggcatgc tgacagattc aagaagtttc ctgtcctaca ctagacatga
    22081 atatttccgt cgtgttcttt gtgaattttt aggcgaaatg gtcatgcgag gagaagcacc
    22141 tgaagatgaa caacttttag gaagtctagt tcaagcgatt agttatacaa atgctaaaaa
    22201 ttactttggc ttttttgcct aattgattaa tagtaacagt aacgaatcaa aaacaggata
    22261 gtgaaataac ggaatccgtt tatccacgtt ttagagaaga agacggacca aatttgctcc
    22321 gtcttcttct cttgctgttc tgcttcattg cctataaacc tttatgaaag aagagataac
    22381 atgcctacta tccatattgc cggtgattct actgcggcag aaaaagatga aaacaagcgt
    22441 cccgagacag gttggggaga aaaaatctct gcttattttt cacccgagat ccagatcaat
    22501 aaccaagcaa agaatggacg cagcaccaaa tcatttatcc aggaaggaag gttagcccgt
    22561 ctagcttcac agtttcagcc gaatgatttc ttatttgtac aatttggaca taacgaccag
    22621 aaaatccaag aagaaagagg tacgcttccc ttcggtagct atttaaaaaa tctgcagata
    22681 ttttttgaat gcgcaaaaaa agcgaacgtc caaatggtct tactgacatc tgtgacgcga
    22741 cgagattact tagaaaacgg aacattgaat ccagatatac ttggagacta tccaaaagcg
    22801 atgcgtgcat ttgctgagaa acaccatatt cctcttttag atgtgttctc aagatcacaa
    22861 gaattgttcc agaccttctc aaaagaagag acaaaaaaat tctacctgca tcttatacct
    22921 gatacttgta aaaattaccc agaaggacta aaagacaata cccactttag tccagaaggc
    22981 gctgataaag ttgcccgaat aattgttgaa ttgataaaag aatcccgtct gcctcttgct
    23041 aattatttac aaaaaggagt ttgagatgtt tccattaaat ttaggcatcc gtgcccacga
    23101 tttagatgtt cgaaatcgtg aagaaatcgt tcaaaaagta tcacagcttc acttgtccca
    23161 tatccaattt gcaccacaaa aagcatttcc tgaacaactt aaattaactg acatgacact
    23221 tgggagtgct gcctattttg gtgaatactt ccaaaaaaac aatatcgaac tttccatttt
    23281 aggatgctat atcaacctat ccagcaaaaa tcaagaagtt cgtgcacaag cattggcaac
    23341 tttcaaacag caaattgctc tgtgctctgc ctatcaagcc aagatgattg ctacggaaac
    23401 cggtagtgtc tctgtcggtt acacaaaaga aaattttact gaagaagctt atcagatcgc
    23461 cagaaattct atcattgaat tagtcgctca tgcagaaaat tttggcgtaa ctgttgctgt
    23521 tgaagcaggg atcaatcatc caatctataa ctatcagtta gctaaacgtt taatcgatga
    23581 agtagcttca ccaaatttaa aaatcatttt agattgtgcg aatttgatgc ataaagaaaa
    23641 tcatgctgat caggaaaaag tgatccgagg tgccttggac aatttacatg gttatattac
    23701 agcgcttcat ctcaaagact atatcatgga aaatggaaag atccgcatgg tacctgttgg
    23761 caagggctgt ttagatttcc gcccggtact gcattatatc aaatatgagc gtcctctaat
    23821 gtacgccact cttgaagcta ctcctgagat ttatgttcct gaagcaatag aacacttgca
    23881 gtttatttac caagattgtt aaggagaaga ttatggagga acgaatacag aaaagttatc
    23941 aaaaatatca tgcaaatgct tttcagacat tgctgcatct ttatcaggga aattattggc
    24001 gttttgccat gtcaggactc ttttttatta tcaaacatct tccatcttgg ttaatgccga
    24061 tcgctattgc caatgtaatc aatgcagctt catcgaaaga ttcttctcag ttgcaggcca
    24121 tttatttcaa cgcttttttg atggcttgtc tgattggtca aaatatattg acgaattatt
    24181 ttcatgtaaa ataccatagc acttcgatcc gtcaagtaga agctggacta agagcgaccc
    24241 ttatcaagaa aatccaagaa ctatctattc cttatcaaaa agaattgcaa tctggacgaa
    24301 tccagtcaaa gatcatccgt gatgtagaag ctatccaaac gttgtcctct caagtatttg
    24361 tcagcggatt aaatatcgct gtcaatttat tcgtagcttt aggtatcacg ctttataaaa
    24421 gtcctgttgt tttcatgttt ttcttattga ctgttcctct cgccgcattc gttactctct
    24481 ttttccgtaa aaggatcaga cagtccaact cagacttcag gcaagaaatg gaagagactt
    24541 ctgcaaaagt gatcgaagtg atcgaattag caccgattgc tcgagctcat gggttagaaa
    24601 aacacgaaac aactcgctta aataagcatt ttactcaaat ctatgaaaaa ggattccact
    24661 tagatatcct gcaatctgtt ttcggatcag tcagctgggc tagttttcag atatttcagc
    24721 tgatttgttt gattttcact gggatattag ctttacaagg gcgcatccaa cccggcgatg
    24781 tcgtgatgta tcagacgtat ttcacgacga tcgtcaattc cgtttctgga atgatcacgc
    24841 tgattcctac gatttcaaaa ggcatggaat ctatcacttc tattggcgaa ctgttgattg
    24901 ctggcgatgt agaaacttat cacggtaaga aaaaaatcca acatttggat ggaaattttc
    24961 gttttgagga tgtttctttt ctttatccgg actcactcaa accgattatc gatcattttt
    25021 ctctagaggt gaaagctgga gaaacaattg cttttgttgg gccatctggc tctggaaaat
    25081 ctacactcct taacttattg attggattta tccagccgac ttcaggaaaa atttttctag
    25141 atgatcagcc tttggatgaa ctggatatgc gaagtgtgcg aaattattta gccgttgttc
    25201 ctcaaaccac tttgttgttc tccgcttcga tcaaagagaa catcacttat ggcttgaaaa
    25261 acgtatcaaa agaacgttta gatgaagtca tcgaagctgc gcaactttct tcactgattg
    25321 accagcttcc tgatggtctg gataccttag taggcgaaca tggcaacaag ctgtctggtg
    25381 gccaaaagca acgtatctcc attgcacgag cgttgatacg tcagccaaaa atcattttgc
    25441 tagatgaagc aacctcagct ttagataacc agtcagagaa aaaaatccag caagccctga
    25501 attacctgac agaaacaccc actactttta ttgtggctca tcggctttca acgatcaaag
    25561 aggcagataa aatcgttgtg atcgatgaag gaaaaatcgt tgaaataggt acttacgaaa
    25621 aactgttagc tcaaaaaggc tatttctacc gcttgaaaaa tgaatgacaa aaaataggag
    25681 ctatgacaag acttttgtcg tagctcctat ttctgaataa acggtgttct cctgccaact
    25741 cctcggtcac aagtcacaat agtcatcaaa catgagaagc tgttttttga aattgttcct
    25801 tgtaactcag agttaaacgg taggctcacg acctcttggt aaatggtgtt caagagacag
    25861 cctatcggca ataagaagca attttgtcat cgctcaaggc cgaacgtctc tttcacaccc
    25921 tctgttgttt cataaaatag ttttattcgc tgtaaaggtc gcgaactggt gtcatgatga
    25981 tacggttcaa gtcattgatg attgtactga agccttgctc tttttgcatc aagtcattga
    26041 ttacttcttc tgattggatt ttcacagcca tttcttgtgc tttcattgca tcttcgtcgc
    26101 tgaactcttg tccactcatt tgtttttctt gtaattcgat ttgcatcgct tggaagtctt
    26161 tgaacagttt gtgtgcttct tcgtttgctt gtactttctc gtacgcttct ttcaacgctt
    26221 tgaattctgg taattcacgg atctcacgtt cgatttgatt cgcgctatcg tagatgtttg
    26281 acatgttatg ccctcttttc ttttagtagt tactctctat tgtaacatgg ggttattcgt
    26341 tttcaaaggg gctactctcc ttgatatttc cgccagaggt ctttagccgc ttcaccaatt
    26401 ccctgaacgc cttctttcac catatcgccg aagtttttca gcccttcttt tgcttgttca
    26461 ccatattgat tcaagttatc ttgccaattt ccagactctc cattagaatt tcctgtgttt
    26521 ccaacttgat ctgcagctac cacttgtcct cctgtggcat aggcatctgc tacactaaat
    26581 cctgtttttg aagtatacgg aaggatgcct tctgccgctg atttgaagac tttcccgaca
    26641 acatttccac ttgtcccttc caaatagtgc agcttgctgg attcttcgta acccatccat
    26701 gtcgaaatca ctacgtctgg cgtgtaaccg atcatccatt ggtcatttgc ttttgtggca
    26761 tcgaaattag tttctgtggc tcctgttttc cctgctatcg tataacctgc aggattcgca
    26821 gcagccgctg ttccatttga aaatgtacca agaagcatgc tggtcatttc atcggctgtt
    26881 tcctttgata tgacctgttt tggttttttg tttgtgttat cgacgatcac cgctccagtc
    26941 gaatcaacga ttttcgtgat aagatgcggc gtatacatct gaccatcatt ggcaaatgca
    27001 ctgtaagcac ccgccatgat caatggagat actccttttt ccagtccacc aagggctaag
    27061 ccataatact tatcagattt tgctaaaggc aggccgaatt cttctgcttt atcatatcct
    27121 ttttgtaaac cgatctcatg caaaagccat acagtaggca aattcaaact ttgtgcaaca
    27181 gcttgataca tcggtacttc tccttggtat gtcccgtcaa aattatgcgc atcgtaataa
    27241 ctttgcggtt cgtctttcaa gatactggaa ggcttgtatc cagcttccag tgctggtgta
    27301 tatacgctta atggtttgat cgttgatcct ggtgaacgac gcatctgtgt agcaaagctg
    27361 aatcctctaa agacatgatc tcctcttcgt cctactagtg cttgtacacc acctgtattc
    27421 ggatctaaag ctactgaagc agattggacc atggcaccat ctgaagcatt tgctgggaat
    27481 aatgcactgt tttgataagt agcttctaat tgcttttgat aatcctgatc taaagctgta
    27541 tagattttat agcctttatt catgacatct tcttcatcaa gaccatactc gttaactgct
    27601 tcatcgatca ctgcatcaaa ataataagga taacgataac cagaatctga attatcgtat
    27661 gtgtcattaa gatacgcgct gatatctgtc tggctttctg cttgttcttg ttcttttgtg
    27721 atttttccgt tttcttccat tacacttagt actgtgtttt tccgatcatt cgcatttttt
    27781 gggtgatcga tcggattata aataccagga cctttcagca ttcctgccaa agtagcagcc
    27841 tcagacagcg taacattcgt tgcatctact ccaaaatact ttctggaagc gtcttggaca
    27901 ccccataccc cgttgccaaa ataggcattg ttaagataca tggtcaagat ttcttctttg
    27961 ctgtacttct tttcgatctc gattgccaaa aataattcct tcgcttttcg atcaaacgtt
    28021 tggtctaatg tcagatacgc atttttggca agctgctgag tgatcgtact tcctccgccc
    28081 cctgatgttc cgccagacaa gaccattcgg actgctgcac gggcaatccc tttgatatca
    28141 aacccgtgat gctcgtaaaa attcctatct tctgtcgaga ttactgcatc ttggatatag
    28201 ggagaaatcg cgtttaattc tacatatgtt cctttttggg cgtacagtgt gccagcttct
    28261 tcgtttttct tatcataaat gactgtcgat tggcttaatc ctgattttaa cgtttcgaca
    28321 tttgcttgtt ttgctaaaat aaagaggtag atacttgtca ctaagacaca gatcaaacca
    28381 atcagcaaaa tcaatttgtt cacatgatat tttttccaga tgcgctttcg ccatcgatgg
    28441 aattgtccga gatatggtct gatccaacgc caaaaactga tcaaagcagc ttttatcttt
    28501 tctaaaatgc tttgaaaatc catttgcttc ttctcctgtc tatttgattc aatcgtctta
    28561 ttttaccata gtgaaagagt gttttcttcc tgcttaagtt gtagttcaat atgttttttt
    28621 acgttagtgc aagtagagta acataagaat gaacagaaaa atgtaagttt tttcttaaat
    28681 atgttttaaa aatggtacaa ttagtctgcg attgcactga aaggagtaca cttgtgaaaa
    28741 tcacgatcac tttacctatg aaccatcctg aaacaacaat tcgcgacttg cttgaaaagg
    28801 aatggttagt tcctagaaag gttcgacact ttttgcgtat acgtaaaaac gtttggatca
    28861 atcaacaacc tgctttgttc catcatgaag taaagggcaa tgaccagatc acattgttat
    28921 tcgaagaaac agattataat tatcaagaag ttcaattagg agatgcgaag cacatccgtg
    28981 ttttatatga agatgagcat ttgattatag tggataagcc tgcaggaatg aagactcatc
    29041 caaatgaacc gacagaaaac agtaccttac tcaatcattt agctgcttat ctcgacacta
    29101 aacagcaacg accttacgtt gtccaccgct tggacaaaga aacaagcggt gccgttttat
    29161 ttgcaaaaaa tccatttgtc ttgccgatac ttggaagaat gttggaacaa aaaatgatct
    29221 atcggagata tcaagccatc gtatggggag aaattgccaa agatatgacc atcaccaata
    29281 aaattggacg agatcgccat gatcggagaa aaagggtcgt agatgataaa aatggtcaga
    29341 gcgccttgac acatgtcact gtcaacaaag tactttctga acaaacacaa gtctattgtg
    29401 ttttggaaac cggacgtaca caccagatca gagttcattt agctcataag ggacatccga
    29461 tcgttggaga ccctctctac caaaatagaa cagctgaacg actgatgctc catgcattag
    29521 aactgcacat gatccatcca tttactcaag aaaaaatagt cggtaaagct ttacctggat
    29581 tatgggaata gaaataaaaa agaacagagt cttatcagca gataatgata agactctgtt
    29641 ctttttgtgt aatttgtctg cttacttttg atgttcgtgt tctgctaaca gcaaactacc
    29701 gataatccca ctttcattcg gcagtcccca acgaacgata tattcactta cttgaggtgt
    29761 ttccatataa ccacccatca attcaacaaa ttgctgacgg attttttgaa ggagatgatc
    29821 ctgattcatt accccaccgc ctaaaataat cttttcaggt gctaacgtca acgtatagtt
    29881 gatcagtgct tgagcaatat aataagcctg aatagcccaa acaggatgat cttgcggcag
    29941 atcttgccct ttgatccctg tgcgtgcctc aatagacggt cctgctgcta atccttctaa
    30001 acaatcttta tgataaggac aagtaccttc ataatggtca tctggatggc gtttcaccca
    30061 aatatgtccc atttcaggat gtgcgatccc tgaaaaaatt tcttcattga tcacgacacc
    30121 tgcaccgatt cctgttccca cggtaaggta aatacaacta ttttttcctt gtgctgctcc
    30181 ttgcttcaat tccccatatg cagcagcatt gacatccgtt gtccaagcag caggaatatt
    30241 gtagcgttcc ttgattgtgc caagaaaatc gaattgtgcc cacccttttt tgggagttgc
    30301 caaaacgtat ccgtaattat cttttgtttt gtcgatacca atcgggccga atgagccaat
    30361 cccgattccc ttcaattcat aacgatcaaa aaattcaaat acctgatcca atgtttcttc
    30421 tggtgttgtg gtagggatac ttaatttttc taaaatttct ccaccatctg aaaccgcaca
    30481 cacaaatttt gttccgcctg cttctattcc gccatacatt cgttttcctc ctcgaatccg
    30541 attgtccgaa tctcataagg ttggattatt gggacaaccg cttgcttcgt tggttcttca
    30601 agcagattca atatgacagt ttttccattg tctttagtta tttccaattt ttctaaatga
    30661 ctagacatat tgaaacctct tactactact ttatcactaa acttgctgcg tttcaaagct
    30721 gtaattgcaa acgtttcact ttttatcgtt aaatattgtt gttttgaaat caatgttcct
    30781 tcatgatgtt tgatttgttg agtggaaaaa ggaatctgtg ctgcgtatgc atgcaaataa
    30841 gtagagaatt tttcttctgg tccatgtagt tcaatgctgt aattgaaccg atgctcacct
    30901 agacactgtg cttctggtgt tggaaaatat ccccaatcgc ctagttctcc cacactgcga
    30961 agtagcgtca ctgcgatttg tccgtcttct gttacttcat attcattcaa accaaagttt
    31021 ccgactgtta caccgtactc ttcatcatga atattgacaa atgcttgctg atgttgcgga
    31081 ttcgtggggt tttcccaact tttagacaca tggtttgggc gcttcaccac ttcaaaaata
    31141 ctatctgctt cgtgatgttc cacatgtaac tttgtaggaa acaagacacg taagcgatga
    31201 tctttcatct gattgtcgag agtcgtttca aagtcgattt ttttactatc ttttctgatt
    31261 gtcatgattg tttttatttg aaggattcgt ttttctttgg atcgttctgc ttttcgataa
    31321 cgaaattcca caaccatctg ctgttctttt tctaaacgct cgtctgcaga aacagggatt
    31381 tccatttcct gtagaatact tatttttgct atttccggtg tatctactaa tacttttact
    31441 tcagagtttt ctttgttact ggataggatt ggctgatcac agaaaggttg tttaaagata
    31501 tactcatttc ctatatcgcc gatatcttca aaaatatgca gattattcaa ctttcgtttg
    31561 tttttgcgat cttccattgt aatggtacca tttttttcaa tcgtcaaatg tagagggccg
    31621 ttttcgatga ttcgtccact ctgatgaatc attgtttcct tttcttctgc tttcgcttcc
    31681 ccttctacaa gcgcgaatgt ttcccaagaa aatgctggca tgttttctaa tggtaaagtc
    31741 actttgatca ttcttgccat atatggcaca cggaaacggt ctttcggcaa atcataacca
    31801 aattggacag tttcttcaga taaaatagct ggtatagtgg ccccactttt tgtttctaca
    31861 tgatacttac gtttaggcaa attttctaac tcttgatata gttgttcagg tattccttca
    31921 gcgaatcttt ttctttctaa ttcgatggtt atttctgctt caccagtttt atccattcct
    31981 gcagtattta caatgacaaa tggaaagctg tcttttggga atccggtcgt atcgattgct
    32041 gcggtcagct gttctaagga atcttgtgca agatactttc caacttcatc tgctttttca
    32101 aaacgaggta tcatttcccg atggacagaa tcgactgaac aaccgcaaat actgtcgtga
    32161 ggatgatttt gcattaatgt cttccaagca taatctaatt gatcatgggg atagtttcca
    32221 ctaacttcat aagccatcgt cgcaagtggt tctgtaatat tttctagctg tcgctggacc
    32281 ttggtattcc attgttttaa gtaaacccga gcagatgctg tattggctaa agtataccag
    32341 ccatccgttt cttgacttgt caattctcct tctactgagc ctaagtcttc tggcacatct
    32401 ttttgaactg cttccagata gtcagtaaaa ttagaatgaa taaactcgta atctggaaac
    32461 agttcatttg cgagatggat tgcttttgat atatcttttt gtaccggttg atgatcaaca
    32521 ccattcatca tcaataagtg gttcgtagag gcatattgtt ctgcatccgc taatttttgc
    32581 ttccaaaagg caagagctgc ttctttttct actggaatct cattcccgtt gctataccaa
    32641 ttggcaaata gcagaccaaa gattgctgtt tgatcaggtc ctttccacca catctctgag
    32701 tattgggaag aatagttttc tgcttccaaa acttgattat caaagccaat tggttttaca
    32761 ccacggccaa acgctgctgc tgaaatacca gcttgtttca ttaattgagg cgtctgtccc
    32821 atatttccaa atgtatcggg aaaatagcct aacatgacag gggttcccca tttacggctt
    32881 tcttccatgc caatcagcat atttctcacg ttcgattccg agctgataag aaaatcatct
    32941 tgcaagatat aaaatggtcc aattctcaat tttccttcat tgattgcttg ttggattgcc
    33001 tgtctttttt ctggccttac ttgaagatag tcatctaaaa taatcgtttg cccatccaaa
    33061 tgaaaactgt tgaaggacgg atcaacttca aatagctcta gtagatcgtc tatcaattca
    33121 atcagtcgca tgtgatgctg ttcgtaagcc atgtaccatt cacgatccca gtggctatga
    33181 gaaatgatat atactttctt tttcatttac gatacctcct acttttctac tctaatatca
    33241 aagtaatcca tgactaattc gcaaaacatc atatttgccc aagaaaacca ttctctcgta
    33301 taattttcag gattgttcac atcgaatcct tcgtgcataa ggtgtgttcc tgcgtcagtt
    33361 gctacaagta aattcaatat ccgctctttt tcagatttgt ctgacgttgt cattccttcc
    33421 atagctaatg caatcggcca aacgtatttt tctggcgtat gggaggatcc aattcctttt
    33481 gcgtactttc cttcatagaa atatggattt tctttactca acaatgttct tcttgtttgc
    33541 agataatctt cctcttgttc agaacaatat cccaagtaag gtgcggcgat cagattgggc
    33601 acattactgt catccatgac tgtggcgttt cccattccat ctacttcata tgcataaatc
    33661 gtttgccctt tttgattaac cgttcgtccg tgattctgaa tcccctcttg gatctctttc
    33721 ttcaatttct gtgtttgctg tacaatttct ttatcatcga gtatcgtttg aaaaatttct
    33781 tccacataac ctaacacgac caccgcaaac atattggatg gtaccagata tccataacgg
    33841 caagtatcat cgctaggacg gaaaccagac catgtcattc ctgtaaaagc tgtttttgca
    33901 cctcgcccgt cattgatcag cgtatcttct tttcttgtcg tgtctcgtac aaatgtataa
    33961 ggagagtgtt catgatcttg ctctgttttg aacacgtcca agattttttt gataccttca
    34021 ataaaagatt gattgaattg atcagttttt cctgtatttt tgtaaagaag ataggccaac
    34081 tgtattgggt agcataaaga atcaatttca tattttcttt cccagatcca atcgttcatt
    34141 tttgtatgat ctgtttggtg gccagcaccg ttagcttctt cgttgaaggc attcgcatat
    34201 ggatcgatat tgatataaaa aaattgcttt ttgactaacc cgctgatcat gtcagctaat
    34261 tcctcatctt cttttgcaat cactaaataa ggacgaactt gtgcagtaga gtctcttaac
    34321 cacatcgctg gaatgtctcc cgtcaataaa aaggtggttc cgtcattttg ctttttgact
    34381 gttgtcaaca gagtattggc aaatgctgct gtaaaattct ttgcccagtc cgcatggata
    34441 tccccacatt tttgtgtgat atcttccata aatttctgca ccgattttgg tatatcttta
    34501 taagccacta ataaaacctt ctttctattt gatatatctt taaagattat acttcataca
    34561 gccaattatg tctacgcttt caaaaaatat ctttttattt actttttcat ccattatggt
    34621 attatttgaa tatgatatat cattaagagg tgtttatatg aatcaaccat tgtaccagac
    34681 aatatttaat gatttgcaaa cggctatttt aactggtgaa ttacctgtag acagccaact
    34741 accaactgaa aaagaacttt cacgtaccta taaagtaagc agaatcactt ccaaacgtgc
    34801 attgactgaa ttagagcaat taggacttat ttatcgcgtt cgcgggaaag gcagtttcgt
    34861 taaatccgct tctccggaac agattcttgc ttctcctaca aaaacacgac ggattctgtt
    34921 tcttcttcca tatgtcgctg atttgtctgt tggtgatttt agcaagggat tgaaccctgt
    34981 gatgcaagat aaacagattg atgtcatgat gacgacgctt gactttctac aaaataaaac
    35041 agcaaaagag ctaatcaatg aatttgacgg attgatttat tatgctcttg atacagaaca
    35101 acatcttgac ttactttttg agctttcatt gaaagaattc cctgtcgtca tattagataa
    35161 aaaaatctat gagttacctt ttcctaccgt tctttccgat aatttccaag gcggtgcgct
    35221 tgctgcctct tatttgatcg aacagggaca ttcaaaaatc gcttatttgt ttggtacgca
    35281 gactcatcca caatccgttc gacagcgtta ccttggttac cttgaagcat tggacaaagc
    35341 tggtttgact ttccacactt cactggatga caaaagcgcg acattagatg aattgctttc
    35401 ttatatcact aagtatgaag taactgcttt tgtttgtgaa aacgatgttg tcgctatcca
    35461 gaccatgaat ctcttgagac agcatggtta tcatatccct gaagattttt caattatcgg
    35521 atttgatgat atccaagcag cagctcttgt tgacccgcca ctgacaacca tcgcacaaga
    35581 ttttgaacag ttaggtaagc ttgcgggaga tgctttggtc acttggttag agacaaaaga
    35641 tcgaccatcc gatagtaaat ttccagtttc attcatcaaa agacaatcaa caaaggagaa
    35701 ataaaatgaa tatcggtcaa atagatacta gacatgcaac agcgaatcag ccaaatttct
    35761 ctaatgggaa ctgccagcct tatactggcg ttccttttgg gatgaattat tttgcaccgc
    35821 aaactacgga tcaaaacggc agctggtggt ttcatcctga tgaccgcgtt tttcaaggct
    35881 accgtcttac ccatcaacca agtccttgga tgggtgattt cagtcatatg ctgtttacgc
    35941 cgatcaatgg aaaactacag gagaacaccc ttttccatgc tcaaagttct taccgcccag
    36001 aagaaagtat attttgcccg actcatctgt cgatctgtca attacgttat ggcatctgtt
    36061 ctacattgat acctagcatg tatggcggaa tcttatctat tgattacagc aaaaatgaca
    36121 gcggtttact tttatccttt ccgggacgcc atcagctctt tgttatagat ccttacacag
    36181 tggaaggaaa aatcacacat tttgctggtt cagaagatcc tgatttttct ttttatttta
    36241 tattgagatt tgaatatcct ttaacaattg atgagttagc tgtttccaac aaaaatagcg
    36301 actcgatccc gttgtatttt gaacagacaa aaaaacaaac tatccgattt gggacatctt
    36361 ttatcagctc ggaacaagca gcttataacc tggaactaga acaaaaccaa agcaaagaga
    36421 cttaccttgc tcacagtcaa gaacaatggc agtcctattt tgatcgtata cagctcacac
    36481 accatgatca acaacaattg cggacgtttt atcataattt atatcgggtg tttttatttc
    36541 cacaaacatt ttatgaaatt gatcctagtg ggcaaaaaat ccactatgat acgactagtc
    36601 gatctataaa acctggtgtt ctctatacaa ataatgggtt ttgggatacg tataaaacgg
    36661 tttatcctct ttattctttg attgctgtag aaaaatacga agaaatgctg gaaggttttt
    36721 tgaacagcta tagagaaagt ggctatttgc caaaatggct gtctcctgat gaacgtggac
    36781 ttatgcctgg gacattgatc gatgcggtca ttgcagatgc tgctgtaaaa gatatccgac
    36841 gagacttgat gcctgaattt ctaacggcaa tggaaaaagg tgctacggtt caaagcaaac
    36901 atccaaatta tggacgccaa ggaacagaag attacttgac atatggctat gttcctaatc
    36961 actaccacga atcagtcaat cacacattag actatgctta tagcgatttt tgtattagcc
    37021 aagttgccaa ggtactagaa gaagaggaaa tgacgaagaa atatcagcag caatcattga
    37081 actatcaaaa tatctttgac tatgagtcag gatttatgcg ttcaaaagat aaagatggca
    37141 agttcagaga accattttca gctaatcgtt ggggacaaga ttatgcagaa ggaagtgctt
    37201 ggcaaagcag ctttgctgtt tatcacgatt tttcaggact gatcggaaaa tatggtggca
    37261 gtgagagata taaagaaaaa ctcattgagc tgtgcaatca gcccccaacg tttgacccag
    37321 gaggatatgg ttttgagatc cacgaaatga gtgagatggc cgcgatagaa tttggacaat
    37381 tagctatttc aaaccagcca agttttcact atccttactt gttcagttat ataggacaac
    37441 ctgaaatggc acagccactg cttaaacagt tgatgactca gaccttcgac gattctccaa
    37501 tgggttaccc tggagatgag gacaatggaa gtatggccgc ttggtatatc ttcaatagtc
    37561 tgggatttta tcctgtcacg cctggaaccg gtgaatatgt tatcggtatg ccattaattg
    37621 acaaggctgt tttgcttttg tcaaatggaa aggaattgac gattgaagca acgcctaatc
    37681 ggccgcagca acaatttatc cataaaatca aacggatgga caaagaatat acgaaattat
    37741 attttaccca tcaagatttg ctgaaaggcg gcacgatctc ttaccaatta gggatcatcc
    37801 ctcaccctaa gaaatatcaa gcaaaagatt tgcctttttc cttatcaaac tataattaac
    37861 aagaggttgt gaaaaagctg tcctgcatca agtaataaga acagccaagc aaaaatagat
    37921 cctcatattt ttcgtttggt tggtcttatt accgcagatg caagcttttg aacaccgttt
    37981 attgagaggt tgtgaaatca gcgttctgac ctgagtatta gagagacaaa tggcaaaata
    38041 gttcctcata ttttgccatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt
    38101 tagtggagag gtcgtgaaaa agctgtttag tttcgagtat taagaaaaat tttgtgaaaa
    38161 tggctttcca catttttgca taaatttggc ttaataccga gaaactggct tttgaactcc
    38221 gtttatcgag aggtcatgaa aaagctgcct tgcctcaagt aataagaaca gcccaaaatt
    38281 agatttctag acaatttttt ataagttatt tcattacatt ggctttttct tttatgattc
    38341 tccactgttt tctcggtact ctttagggga tctgccgacg attttcttga ataatttaga
    38401 gaaatacgtg gtgttgttgt agccaatctc acttgctatc tcattgatgt tttgattact
    38461 gtgcaaaagc agttgtttcg ctttttccat acgtaaatgg ttcaaataag ctgaaaaact
    38521 ttttttcgtt tcttttttga acagctgtcc tagatacatg acatttaaat gcaggttttc
    38581 tgacacttct ttgagtgtaa gtggttcttg ataatgctgg tgcaggatta cgattacttt
    38641 ttccacattg tcactgtact ttttctgtct ctgatgcttt ttgatgaatg acagaagtag
    38701 ctgctgaagt tcttgcaccg tttttgcctg atggattttt tcgattcctt gtaaatattc
    38761 ctcatcttcc agatcaatca attcccgttg aatctccata aacagtaaaa aactggaata
    38821 tcgtatatct tccggcatca tggctgctaa ctgaaactgt tcaaaaaaat cagtgatcat
    38881 tttttgagcg acttccaatt gtttattttg cagcacgcgt ctgaaacttg aaaaatcgat
    38941 ggtttgatct tttgtttctg cttgtactgc gtaaaaaaca tgctcgtctt tatctccata
    39001 aaattgatgc aactgtagat tgtctttcgc ttgttggaat gtttcaggga ttttgtccaa
    39061 agaatctgtc tcttccccga tactgatcag ccattcctga tcaggaaagt tttcttgaac
    39121 aaaacaacag aagccatcaa cttcatctgc ctccaacaac aacgtgatca atacacggtc
    39181 tccgtaattt cgttgatagt aaaagatttg ttgccgttct tgcaaccatc tattgataag
    39241 agtatcatga gttcttgcca gttgaatcaa tactatccta tgctgcttct cacttatttg
    39301 tcctattatt tcttcttcac ttatttcatc caattcttca ttcaaccatt gactgaataa
    39361 cagttcttga tagatttctt gttgattttt ttgttcattt tgctgatcta accgtgtttt
    39421 gattttcttg aggctttcaa ccaattcgaa cttattcacg ggtttcatca aataattcac
    39481 ggcgcctaat tgcatacctc ctttcaaata atcgaattct tggtatcctg ataaaatcat
    39541 aaattcaaaa ttatgacgtt ctttttgagc cgcttcaata aattccagtc catttatttc
    39601 tggcattgtc acatccgtta ctactaaatc aatctgtcgc tgttcaagta cagctagtcc
    39661 ttctttggca ttctctgctg ttgctactat ttgaaagcct aaactttgcc aatcaattat
    39721 cttttttaac ccattcaaaa tcatgtattc atcatctacc aataacactt gatacacgct
    39781 catccctcct tgaatgtaat agaaacggtc agtccacctg tctcattatt ctcaagcgac
    39841 atataataac tgctgccgaa gctggcacgt aaacgttcat tcacgttttg cagaccgata
    39901 gaaccgtgaa gttccacttt aggatgagac agtttttctt caatctgttt tagccgtttt
    39961 tcagtcatcc cttttccatt atctttgatg atgatcctta cccgtttgcc ttcctgcaag
    40021 actttgacac ttagcgcatt atcgaatcga gtaaaatcaa taccgtgttt aaaataattt
    40081 tcaactaatg gctggatcac aaatttaggt acttcgatct tttccaaatc aggatcgatc
    40141 ataaaatgat aggctactcg attaggataa cgcatttgat acaaatagac atatttttcg
    40201 caaaagtcca gttcttcttt taaagtgatc gttttctctt gattcgtatt gtttcgaagc
    40261 aaagcggaaa acgcatacac aacatctgct aattcttcac ttccttcgct gattgcatac
    40321 attcggatat attctaatgt attatataaa aagtgtggat tgatctgtgc ttgaagcgcc
    40381 cgcatatgtg cgtcttgctg tttgatttct aatttgtaga tgtcttctac aaactgattg
    40441 atgctatcca acatttcgtt gataccgatt gaaagttcct tcagttcata ttccgtgttt
    40501 gttatgtcga tccgcgtctc taaattccct gctgctgttt gatccatggc ctgcatgacg
    40561 atagatactt gctgtgaata tcgtttgaat gttttataaa gaaagataag cagtatattg
    40621 tctaaaataa tgataccaat gatcagcggg gcaagatttt ttcccgtttc gatttttaca
    40681 ctttttttat ctagtacagc taatatacga taatcatcag acagttcttg gtgttgaaca
    40741 aaattgtttt tttccagatc gtcaatcggc aattgtgaat ttttcttcag actctctgtg
    40801 atgatcattt cttgtctttc aaacgtttct ttagctattt tattatcatg gaatgtgtat
    40861 agtcgatttg tcgttccaga aatcatgtat aaagagagtc cattgaatga cgttagattt
    40921 tctaaaatca tatctagttc tttcttttga aaaccaataa aaatacttcc tgactcagct
    40981 cctccttgtg tgataggcaa cttgatataa aaggcgtcta gtaattttgg tgtccccttt
    41041 tttatttccc cacctttgtt ttctctagaa gattcataat actccggtag ttgattcaac
    41101 acgatatata tcgcacttag ttcttcataa tttgcgtaga gatctttgat ttgatttggg
    41161 aaagaaacta attcatcggt actgttttgc tgttcgtata catacatcag atactgatct
    41221 atgggttttg ttaagtaggt cgtcacattt tcgatctttt cggaattccc tacaagctgg
    41281 tttttgatga tcctactcaa ggttgtttta tcattcagca ttctgcttgt gctttgaacg
    41341 gcatcacttg tcatgttttc tgcctgtttt tgattttgtt cccaagtatg gatactaaaa
    41401 ataacggtag cagtcatcgt tacaccgatc atgataaccg cgtatttccg caacagacga
    41461 tttagtaagg ttccttttga aaatagaatc cgaaacttat tcataacttt ccaactgttt
    41521 atctaattct tcacgccaat gtgttgtcat cgtaccattc caaaccgtca aaagaccaat
    41581 gacaccaaac aggatcaatc ctttgaattg ccaagtcacg cctaaaatta taccgctacc
    41641 aataattatt tttagaaaag acgaaaagct ggaaaaaacc gaaataaaac ttagctttag
    41701 cagattagga acagagatcg tatattcact atctaaaatc atactgtatt gataagtagc
    41761 aaataggcag agcaaggcaa aaagtaaaat aaaatcaata gctaaaaaaa tgagcccttt
    41821 gatttgaaca gataaatata aattgtaact caataaagca gtaccagata aaaataaact
    41881 aaatagcaga ttgcctctta aaaaatttct tttatatata ttccagcctc tttttattgt
    41941 gatttcttta tactcgaatc cgtacaaata aaatagttca ttgactgttt tccatgccgc
    42001 acctaatcca aagatgatcc cgccggcaaa tgtatatatc cagaaataca aggttagttt
    42061 tataatgacc cagatccgga taaataactc ttccaaaacc ttccctaaca tatcttctcc
    42121 tccaaacatt aagtttatac tttctcatta tacaaaaaaa ggttgggcaa tcagcacctt
    42181 gacctgatta ttagagaaac aaacggaaaa atagttcctc atattttgtc gttttgtgag
    42241 cgaataccga gggttagctg attgaacacc gtttaccaag agtttgtgaa atagccgctt
    42301 agtttcgagt agtaagaaaa attttgtgaa tatggctttc cacattttta catatattta
    42361 gcttaatacc gagaaactgg cttttgaaca ccgtttattc ggaacaagag gttgtgacac
    42421 gtcttttgtc acaacccctt tgtctttatt cattattatt cttgtcggaa ctcatcatat
    42481 tgtttttgca tttctttcaa taccttatca tagccagcct tgtccaaagc gtctttcaat
    42541 ttcggtaatg tttcatctgg atcaacagtc cctgtattca atccatctaa atattgattc
    42601 atgacattag aaatattact taattctgtt ttgacactgt cagtgttgaa gctgaatcct
    42661 aaaatcggtg aagtttctgc atcagcaatc gattgatcac gtttggcaat catgtcatcc
    42721 gtaatagact cttgtgtata tagaatcttg ttgtttcctg tattccaagc agacatatgt
    42781 gtatttggct gataaccatc tagcaatttg attttatcat ctgaaccatc gactttttcc
    42841 catgcttctc cctcgatccc ccaaacaagc ccattcaata attctggatc actgttaagc
    42901 agccctagaa gttctactga tttttcttta ttttttgaag tatttgatac gacaaaattt
    42961 gccatttgtg cttgagctgt agattttagt ggaacagtaa ttgcttttga gacaagttct
    43021 tgttttgctg catttgtcaa aattgtatcg ccataatcat acggtccttg tgtttctcca
    43081 cgcattagcc aagtatttcc ttctagtgga taatccttat tgctcgttgc agcgtcactt
    43141 ggaatgagtc cttgtttgta ccagctatgc attgtacgta acagtccgat atacgtttca
    43201 ttatcgtatt ggttgatgat tttcgaatca tctccatcca gatcaatagc aaatggtaac
    43261 gtattcccta aaggataatc aaagttccct tggactttga agccttgtcc aatggcaaaa
    43321 gctgccgtgt ttggttcttt ttcatggaat tccttcaaga ctttttctgc atcagcgtaa
    43381 gattggattc catcaattga aagatcgtat ttatctagta aagctttgtt aaaagtaagt
    43441 acttgttgag caaagacatt tccattgact gggaaagcat ataattttcc attgaccaga
    43501 tttcctttaa tatatgcttc atctaaatca ttataagctt tttcagcgta cttaggcgct
    43561 aattcagtca aatcagcaaa ggctcctttt tgggcattgg aaacatagtt gttcgcaaag
    43621 gcgatatcat aattttcccc ggaagaaatg atgacgttca ttttcttttc gtaatcgccc
    43681 cagccaatgt aattgatatt gacttttaca ccgatctctt tttcgattcg tttgtttgct
    43741 acttccatca attgatcgaa attatctggt ttatctccga tttgatacat ctgcaaagtg
    43801 tccgaattgc tagcttctgc ctggtcttta gaaccagaac ctccgcatgc tgctaatgtt
    43861 cccaacaaca acgctgaaac acctgtaaag gctagtttct tccataactt catttttctt
    43921 cctcctaatt ttatgattta tatttttgtt tctttattct tttactccgc cgattgttag
    43981 acctttgaca aaatgcttct ggaaaaatgg atagctgatc gcaataggca acgtcgagat
    44041 gactacgatc gccattctgg cagattctcc tggaactgag gctaatccgc ctgtcaattg
    44101 gcttcctgct cctgaatttt gtgtcagata ttgaatatta ctttggattt tcatcaaaag
    44161 atactgtagt ggaactagct tatcatcttg gatgtatagt aaagcattga accagtcatt
    44221 ccagtaaccc aatgcggcaa ataaactgat tgtcgcaata cctggaacag ctaacggtaa
    44281 aacgatctga acaaatattc gcagttcgct agctccatcg atccgtgccg attcaataat
    44341 cgaatcagag accgaacgtt taaagaatgt gcgcatcaca ataatattga agggactgac
    44401 agccattggc aagatcaatg cccaaatcgt atcttttaac tgaagaagat ttgtcataac
    44461 aagataattg gccaccatcc ctggtgagaa caacatcgta atcaaacaaa aaacggtaaa
    44521 aaaacgacgg aatggaaagt ttgaccgtga aatcgcataa gcatataaag aagtagccgt
    44581 gctattgatc agtgtaccta aaacagtaac aagtacagtg acgaaaagcg cttggaaaat
    44641 tttatcctgc atctggtcga acaagtacgt ataaccaaat atactgaact tttctggcca
    44701 aaaactgtac ccgtgagtcg acaatatgga ctcatcggta aaagagatgg cgataacaaa
    44761 tataaatggc aaaatacagg aaatagcaaa gagtgcaatc attatattag agaaaaaatt
    44821 agccgtctta ttgaaagagc ggacttggac tctctccact ttcttttttt tcattttttt
    44881 cctccttaga ataatgcaga atcgctatca aaacgtcggg cgatcgtatt tgtgatcatc
    44941 aacaagacaa agccgacaac tgattggtaa agtcctgcag cagccgtcat accaaaatct
    45001 cctgtggatg tcaggccatt gtagatatac gtatccaaaa cttgagtcac atcatataat
    45061 gcaccggaat tcctaggaat gttataaaac aggccaaaat cagctcggaa aatgtttcct
    45121 acggctaaaa tcgttaaaat cgtcattagt ggaataagtt gtggtatcgt cacatgtttg
    45181 atctgctgcc atttgctagc tccatcaacc atagcagctt cataataagt cggatcgatt
    45241 cccataacag atgcaaagta aataatgctg ttataaccaa tccctttcca tgtaccaatg
    45301 aacaccaaga taaacggcca atatttcggt tcattatacc aattgacagc ttctcctcca
    45361 tgtccagtga tccactgatt gaatattcct ttgtcaggac ttaaaaaagc gtaaacaaag
    45421 taactgataa tgacccaaga tagaaaataa ggtagtaagg acatcgtttg ataaacttta
    45481 acgagtcgtt tatttctcaa ctcgctcata atgattgcaa atacgactga gatcagcaga
    45541 ttcaaaagga taaatgctac attatataaa attgtatttt tagtgatgag aaatgcttga
    45601 tccgaagaaa ataaaaattt gaaattttcc caacccaccc aaggactttc cctcaagcta
    45661 gccaagaacc catctgctga aatatgaaaa tttttgaatg ctacgacatt cgccattaca
    45721 ggtatgtaaa agaaaaaaat catccaaagc atacccggta cagccatcag gacaagtgct
    45781 ttataacgcc atagattcat aaaaaaatga ttgaacccct ttcgtttttt catctaaaaa
    45841 cccctttcga ttcattcgca acgtaattat agcgctttca ataatgagaa taaataaaca
    45901 aagtataggg aaaatgaaac aaagtatagg agaggttgtg aaatcagcgt tttggcctga
    45961 gtattagaga aaaaaacggg aaaatagttc ctcatatttt gccgtttttt gagctaatac
    46021 cgagggtcag ctgattgaac accgtttatc agaggttgtg aattcagcgt tttggcctga
    46081 gtattaggga gatcgtgtcc ttactatcta actctgagtc acaaggaaca atggggactg
    46141 taacaaaagt cttgtcacag tcccttattc cgaacaaacg gtgttccaga agtagcttct
    46201 acggaaataa gccgaaattt cacaaaaaag ccatccgaaa gtcagacgga caagtctgct
    46261 tttcagatgg cgctacaact actctgctta ttcttttagc tatccattca attatttttc
    46321 tctcacttgt tctagctctt ctttggtcat gggtcgatat tgccctttat tcaaatcttt
    46381 aggcagccaa aattttccca tacggattct ttttaaatat aagacttctt ttcctactgc
    46441 tttgaccatt cgcttaactt ggtgaaactt tccttcatgc aaaatcagac ggataattga
    46501 agtttctgtc tcttgatcta cttgatcaat ttggagtttt gccggcaatg tctgctcatc
    46561 gccatcaata atcagtcctt ctgcaaataa acggatatct tcttctgtca ttataccgct
    46621 aacctcagct agatattctt tctccacatg ttttttaggt gatagtaact gatgggcaaa
    46681 caccccgtca ttcgttaaaa tcaagaggcc ctctgtgtct ttatctaatc ggccgactgg
    46741 aaaaagatct tcccgataat cctggtcttc caataaatcg attacggttt gatcatgatt
    46801 atcctgagta gcagaaatga ctcctgcagg tttatgcaaa atgtagtaaa aatctttttg
    46861 atacgtaatg atttctccta aataagtaac cgcatcttcg aattcattta cttgcgcttt
    46921 atcgcttttc accacttgtc cattgacttc gatcgttcct tttttgatta atcctttgac
    46981 ttctttgcgg ctgccaagtc ccatatctgc taaaaactta tctaaacgca tgcgtttccc
    47041 ccatttcaaa agagcatcaa tctagctctt ctgattcact tattttattt ttaatttatg
    47101 tcgtaaacgc gctattcctg gtcctagtag tctttctgcc aagcggattt tcaaagctaa
    47161 ataaccatac actaaagccc ctatacctgc tactacaaga atcaacaata gagactggaa
    47221 tttgctatct tcgtttaaaa aagcaccaaa aatcatcttt gtgatccacg aagccaaaag
    47281 cataatcaag gtaagaataa agatcagcaa tgtcctgcgc cagacaaaac ttggtttaaa
    47341 gcgggctact tcatggattc tctttaagat caaggtacaa gacacagcaa atccgatcat
    47401 tgtcgccaat aaagggccgt atacttcaaa taaacgaatg gctgggtatt gaagaaggag
    47461 tttcactaga aacccaataa ccaaataatt aattgccgcc ttgttttcaa acattccttg
    47521 cagcatgttg gaaactagca tatatagtcc taggaagagt cctacaaaac ttgcttggat
    47581 cagtacatta cttcctagag aatccggtgt ataaaataat gtatttagcg gataggcaag
    47641 taacataaca ccaaatgtcg ccggaaacat aaaaaatgaa aacaactgta aatttccgct
    47701 tgtcaatttt gccagaccta ctcgatcttt caacgtaaca gcttctgtaa tcaacggtaa
    47761 cccagtagac gcgatcgatg ttgccaatgc aataactacc atcgtcaact tatctggatt
    47821 ggcactaaaa atcgaaaaaa gatccagtaa ctgtgcattg gaatactcgg tggatgcaga
    47881 catgatcttc ataaaagtga actgatcgac taatttgaag atcgttaccc ctgaacccac
    47941 aataataaac ggaatcgctt ctttaacggt atctaacaac aattccttcg ttgcaatatt
    48001 tattttgttt tcgctgtagt gaataaacgc cgatgtatac gcttgatgtt tcttcaaaaa
    48061 atacaaaagg acaagaatac ttgctagcat accgataaat gccgcgaaag ttgattgcgt
    48121 gaccgccgtc acatagtcac catccatgac tttcatgatg atgaatgtag ccaatagcat
    48181 ataaaaaata cgtgccacct gttctacaat ctgcgacagc gcataaggca tcatttcttg
    48241 attgccttgc aaataccctc gtatcacact catacaagga aaaaccaata cagcgatact
    48301 caaagaacgc atcgttggaa tcagttcttc tccgccacca gaagcatgag ctagccaagg
    48361 agaggcgatg tacatgaaca aagcaaacaa caggcctaac ccgcccatca tctgtaatgc
    48421 acggataaat aatcgtcgtg aagtgccata ttcattcaat gaattatagc gtgcagtttg
    48481 ttttgcaatc gcagcaggta ttcctgctgt agagatcagt agaaacaatg catatatatt
    48541 gtatcccata ttgaataatc cattggcagc cttagcattt tcgcccatcc aagcatacca
    48601 gggaatgata tagacagcgc ctagcaatct tgaaatgata ttactggcgg tcatccaagc
    48661 agagcctcgt gccatttttt cttgcggtgt taattgatct aatgctggtt ttctttgatt
    48721 atccatcggt cagattccaa ctttctacaa aacattacta tcattttaat tggtaaaaca
    48781 gaaactggca atcgatttta tataactttt ataagaacaa ttgttttttt gaattcggtt
    48841 tcgttttttt ggtaaagtaa agaaatatac agccttttat ggctaacatt tataggagat
    48901 atcaatgaca caagaaataa aaaaactacc cgttatattt ttaggtcttt tctttatcac
    48961 agttggattg aattggttct tgctccctca cgatatagct tccgccggag tgggcgccat
    49021 cggacattta gttgaaacgg ccttttctat ccaacgctca gttactgttt ggagcatcaa
    49081 tcttatgatg ctgcttctag ccgctgtcct attaggaaaa tcagtatttt ttaagactgt
    49141 agcgggaagt ctgctttttc ctgttgtttt agagattgtt ccaaaagtgg aaatgatctc
    49201 ctcacatttc ttttcactga tttcaggaag tcttttgttc agtcttgggg tttacacatt
    49261 gtacacagtc ggggcctcaa atggcggtat aacgataccg ccgattattt tccacaaatt
    49321 ttttcggctt ccaatgccgc aaggactttt acttaccaat agtcttatcg tctttttgaa
    49381 ttattatgtt tttggattgt tggagacact attcgttctc ctatctatta cagtcagttc
    49441 attgtttatg aaaatactca tccgcttgtc ccctgtgtca agaaaatttg aataaagctg
    49501 gattttgtca tagcggaaac aaacgatata ttaaaaagag tgtgctataa taaaccaaga
    49561 aattgaataa agcgagggat caatcaatga gcttctcttt agaagacatc cgtcatttac
    49621 tattaaaaga aaatctatta aaagaatttg tttcaacaag aggctggcat cttgatgtac
    49681 cagaaaaagc tgaatttctt cagttaagtt atgattcaag aaaagctgat gcttctactt
    49741 tgtttttctg taaaggaatg aatttcaaag aagaatattt ggattcagca atcgaacagg
    49801 gtattcaata ttatgtatca gaacaaccat acgaaaattc agcagtagga atcatcgtaa
    49861 cggatatccg taaagcaatg gcgcttcttg ctatggcttt ttacgactat ccgcaaaata
    49921 aattgaaagt gatcggattc actggaacaa aaggtaaaac aactgctgcg tactttacaa
    49981 aagcaatctt ggatcacaca acaaataaaa aaacagcatt gctttctact atgaatacaa
    50041 cgttagatgg caaaacatat ttcaaatccc atttgacaac gcctgagtca ttagatttat
    50101 atcgtatgat gtcagaagca gttgaaaatg gtatgactca tctagtgatg gaagtttctt
    50161 cacaagctta caaaacacaa cgcgtatacg gcttgacttt agatgtcgga atcttcttga
    50221 atatctcgcc tgaccatatc agtccgatcg aacatccgac atttgatgac tatttctatt
    50281 gcaagcgaca attgatcttg aattcaaaaa cagttgtttt aaatcatgaa agtgactatt
    50341 ttgatttact tagggaaaca gccgatctat tccagattcc aacgatcact tatggtcgtt
    50401 cggaagaaag caattatcaa gtgatccgtt cagataaagg tactcacggt tttactttat
    50461 cttctcatga agatcgctta gctatctgcg atactgctta tgatattttg ctggctggag
    50521 gattcaacca agaaaatgca gccagtgcga tcattgccgc agcactaaca ggtgcctcca
    50581 gtcaagatgc acaagacgga ttaaaagaag ctcgtgtacc aggccgaatg gatcaattga
    50641 tccaatccaa tggagcgcat gtctatgtgg actatgcaca taattatcta agcttgaaaa
    50701 cattgctgaa atttgccaaa aatgaacatc cagatggccg tgtaattgtt gtattaggca
    50761 gcccaggaaa caaagcaatc tcccgtcgac atgattttgg aaaagtgcta tcagaaacag
    50821 ctgacatcgc ctttttgacg gcagatgacc cagcatttga agatccgaaa aaaatcgcgg
    50881 aagaaatcaa tgaagcaatt actaatccag atttgatcgt tcattatgaa atggatcgtc
    50941 ctgaagcgat tcgacgcgct ttagcagaaa gcgctccgca agattcagtc gttattgcgg
    51001 gaaaaggcgt ggatccctat caaaaaatca atggtgtaga tgaaccttat gaaggggatt
    51061 atgcaatcgt gaagcggttg attgaagaat aatggtattt atatactagt ggtttcccat
    51121 ttctaagaaa aaaagggact gtgatttttt gtcacagttc cttttttctt agaaatcatt
    51181 ttaacttttc actagctaat tctgctgcct tttctctttc ttcatttaat aatttattat
    51241 catagaattt gataaatggg aaccagataa tgaatgcgat gattgcacaa atgactgcta
    51301 acacagcagc tttccaatca ccaccactac caacaaatgc tccgatcccg actggtgaag
    51361 gccacggcat ctgtgcaagc atcggtttga cgatttccag ccgaatggca aaataagcga
    51421 gtgtagcaga agccatcgga gctaagaaaa acggaaccgc taaataggga ttgtagacga
    51481 ttggcatccc gaaaatgatt ggttcattga tattgaataa tcctggtaca agtgaggctt
    51541 ttcctaacac tttcagctga tcagatttcg cgaggaatgc aataaagatg atcaatccta
    51601 aagtcgcacc tgatccacca acggttacat aagaattgtt gaattctcct gccaacggat
    51661 aatttgcgcc ttgtgcgtta gctgccatat tagctaatac gatcggggtc aagaaagaag
    51721 tgatgatatt cgctccatgg atccctacga tccacaatgc atggatcaag aaataaatca
    51781 ccatgacacc aagccatgta ttcgtcaact gcgtaacaaa cccaaatggg atagcaatca
    51841 ttttgaagat atccgttcct agtgcaacta ataatccatt gatgatcatc accacaaacg
    51901 caatgacaaa tgttgggatc agagcagtga aagaacgaga aactcctggc ggaacaacat
    51961 ctggcatttt tatgacccaa tttctcttga cacacataca atacaattcg accgcaataa
    52021 tcgacataat aatagctgta aagattcctg aagttcctaa acgttcgaca aaagagccca
    52081 tcctaatacc atttactaca gtttctgtct cattgataga agcaatcaag ctgattttac
    52141 catcagtcat gatcaattca gggatacaca taaagaatgc aaaaacagat agtaatgccc
    52201 ccgtgagcgg attaacattt aatttttgtt catctcgttc aattgacgtt aattcataag
    52261 caaacacaat ggcaaagtaa atagataaaa tccccatcgt cattgtattg acgatcatgt
    52321 acaagtcact aactttgaaa aaagttgcat taaaaaatcc ttctaaaaat gggaacggta
    52381 atggcaaaat atttaaaacc aaaaacatcg agcctacaat cgtgaaagga atagaagcca
    52441 tccccgctgc catgacagcc cgaacgattt taagttgcgc aattttcccc ataggtccca
    52501 tcaggtattt ctgcaaaaaa tcaaacatta gttattctcc tttcctaaat ataacgcttt
    52561 ttcatattgt ttaatacgga tatactgttg gtcttggttg agtgaaattt tctttaaacg
    52621 atactgtata aatgcactgg caaaaatacc gcttacaaca agaatgaaaa caaataactg
    52681 tcctccattg ttatttgcca taaaaggata caagaatgta aatcctgagg taaacaacac
    52741 tggaatcact aataaattaa agacactctg gaacaaaaaa taccactttg tccatggaac
    52801 gttcgtttgg tgttttcgat aaagctttac ttgttctcct actgcaggca aaatagctaa
    52861 aatcagaatc atcggtaaac tacttcctaa acttttagct gatagaagca gaatcatcca
    52921 ttgcatgttc atgaaaaaga aaaaggcagt caggtaacgt acgattagat aacgattgaa
    52981 atacatgttt ttcaaactaa gttgcttttt ttctaattcg attttccttt ttactgtatc
    53041 ctgcacaatg atccttcctt tctatttatt tttttgatac aaataattca tttcctgtgc
    53101 aacttccaat aatgtcatcg tcgtcatcag atgatcttgt gcatggacca tgataatttc
    53161 catttctatt tttgtcccgc tggcatattc tttcagaagt tgagtttgtg actgatgcgc
    53221 atgaagaatc tcttcatttg cttgtcgcaa cttctcttct acttcttcaa acatctcttt
    53281 acgcatcgag cgaaatgctt catgtatcag tgtccgtgca tttccgctat ggaaaatgat
    53341 atcaaaagaa gtcacttgta gtgtttcact gtttattttt tcagccatct gttttcctcc
    53401 ttattcgatc agtttgataa atttactgct gaaattctca aaaataggtt cagctaagat
    53461 ttcctgctgt acttttagct ggtcaactaa cctaacgatt gctttagtca cgaccgtaat
    53521 tccttcattt tcgacataag aaggcgaaac taaaaaaaca aaatgaattt cttgatattg
    53581 atcccactgc atcccagaag gaatcaatgc aacggctacc tttgtttcga ttccaactgg
    53641 aacagcggga tgtgggactg ccactgtatc actgaatatg atttgtccca tattttcacg
    53701 ttgctggatc tgctttcgca tttctcttat atatccttct tcttcattta tgctcagctt
    53761 ttgcagcaaa tcatgaagaa tttcttcctt tttcggttcg tacgtataag tcttgaaaaa
    53821 tttttcagac aactgttcgg tgtaaatctg ctttttttgc tgtagagaaa atgctggtat
    53881 cggtctatct gaggaatgat agggtataga ttctccaact acctttcgta ttttacgaac
    53941 atcatcttca ttcaaaaaaa tactgacatg taaaactgga attttgaaaa acattgtcga
    54001 aagatcaata gaagaaataa tcaggtcgat tccttttaaa gttgtttcat tgatctcata
    54061 atagcctttt acacttacca ctgtaatatt tttaccgaat tcactgacta cgcgattctt
    54121 taatagttgg gcactgccgt aacccgttgc acagataatc aatgcatgta gtttatgcgc
    54181 agctctttct ttttccaatg ccgccatgag atgcaaagcc aaataggccc attcatcttc
    54241 attgatggta tagtttttca aagccggcat gttgctgaaa tgccttttta ctgcgtcaaa
    54301 gactttggga ttttctttct ttatctcctc agtcaatggg ttctcaatgc gaatacctcg
    54361 gctcaatcga atcatcatcg gtgacaaatg atcgagtagt ccattgaaaa gctggagatc
    54421 ctctactaat gaaaaatgaa attcctgaga caatcttttc agaactttcg ctaattcctt
    54481 tgatagttcc tgatcatttt gattttcttt gtgattcgac ttagccatga gatgtaatgt
    54541 caaataagca atttcttctt cgggaaacga tacacctgcg attacctcaa tacgttgaac
    54601 gatccgctgc gccacttgat actctactcg cttagaaact tcttgttcga tgcctaattc
    54661 cttgatttca aacccttctc ggagccgttt gatccccaaa gccaagtgta aagtcagatt
    54721 ctgtatgata aaatccgaaa cttttaactt agcttctctt gtttcatcga gaatgataat
    54781 gactagctct tcaaaactga tgtctgggaa aaaacggctt tgccctaaat attctttcaa
    54841 tgaatttcca taatggtttc caaaaaaagt atccatgata aaatgccgtc gatttctttc
    54901 ttccccttcg atccatgtcc cttgaccatg cttagaaacg atttttagtg aatatggaat
    54961 caatcgctcc ttgatttctt gcatgtcctt tgtcaaactg gaacgactga tataaagctc
    55021 ttctgccaaa tcatccataa aaagaatggc atcttccaaa agcaattggt tcaatatata
    55081 cttttgtcga tcttcggact cataaaatcc ttgcggttct ctagcatatc caggtactat
    55141 ttcttgccga ctcaaaaaca agtcaaatgt cagtctttgt aaaatatgca gttggtagcc
    55201 ataacctggt ttagcaatga tcttacctcc gtttttttct actaactctt tgatccgctg
    55261 caagtaatta cggattgtcc gatcagataa taacaattca gaagctaaac gttgactggt
    55321 gacatactcc ttcttgtgat caatcaaata tctcaacagc aatttttcct tctgtttcat
    55381 tatcatccac tcctattcca tcatatgttc tcttcgatca cctctgctaa cttctggatg
    55441 cctgtaggga ttgggacata cgcttggaaa gggatactaa caacaggctt tccaacagat
    55501 tctcctaatt ttttgaattt atccaaaaac atcgtcgttt gcgggctgat cagaaataaa
    55561 tcaaaatcac tattcttaat catattatcg ccttctgtag ctgaaactgc atctacgagt
    55621 acctcttctc ttttttgctt aaagaaatcc gttgtctttg aggccatcat cgaggatgac
    55681 attcctgccg cacaaataat caatgctttt ttcataaatc aatcactcct tttattttta
    55741 taaaccaagc atatcttgta agcgttttct attcaaaata tatatttccg tagcattgcg
    55801 gaaaaaatgt gtatcatatc ttgaataata atttctggca ccgtgatata ctagtgatag
    55861 aattttttca ggaggggatt tagtgagtat cacagtgaat attttgtata caagtacaaa
    55921 tggacaagcc agaaaatttg cagaagaaat ggtcgaaaga aacattgtca aagcgattcg
    55981 tgcagaagaa ggaaacgaga aatatgacta ttactttcca ctagaagatc cagaatctct
    56041 tttactgatc gaccgttgga aagatgaaga agcaatcgaa aagcatcaca aatccgaaat
    56101 gatggctcaa ataaacgaac tccgtaaaaa gtataaatta aaaatgaaag tcgaacgttt
    56161 cactgattta ccgtaaaaag atacacatgg aatgatagca atttatcatc catgtgtatc
    56221 ttcacttttt ccttattttt tattcgatct catctaatga ttcaaaccgt gtttttctct
    56281 tatttttcgg ataagtattt cagtcacccc aatatacatg attcctaaac ataccccaag
    56341 gatattctca aaaatgcgga tcgttactgc tcctggaacc ccgaataaac tggcagtgat
    56401 tgccaaagca ccaaaagaat taaaaactgt tttatatcta taggtagaac aaacacctaa
    56461 agctagacca cctaatatac cgacccagtt aaaaggaata aattggctga taccaataaa
    56521 taaaacacat ccaatcaatg agccaatgat tcggtctact gctcgttctt tgaaaccaat
    56581 cgacatcaat ccatagctag atacaataga agaaaatgca aaccctgccc acatcaatcg
    56641 ctgaaaaggg acatactctc ctgcaacgat caaaagacta atgccaaatg catagatgag
    56701 catccaaatt ttttcctgcg aatacatgcc tttcaaaaaa atctctttaa acaagctttt
    56761 gtctttgttc ttttctcgat gttttctgta aaggagaact gaaaaccaac aaaaaaacaa
    56821 aaataataag ctacttgttt gtgtaaagaa attcttgttc aacgaatctt taggtaacga
    56881 ataaacaata aagagatatg aaaagccgta caaagaagca ttccccattt tgggatcact
    56941 agcggttgcc attaatatgc tgcttagtaa aataaaatga atcaacatgc ccataactga
    57001 ccatttgatc agctggacat acggtgctac taatagtgag aacatgacga ttgctaaacc
    57061 tatgatcgaa tgggaaatct tataaccaaa gtcaacaaaa cgaatactca tcaacataca
    57121 gaataaaacc acagcgtatg gtttatgctt cgattcaaat aatgttgtaa ttataatgat
    57181 aaaacaaatg gcaaacaata cgatgaataa tgatcgtaaa aacaatgaac aaatatacat
    57241 gcacttttct tttttagaag ctgcttctcg tattttttgt tttaaaataa acggatctag
    57301 ttgtagagac tgataaaaat ccacctgttg tcgtcctttc tttttacttt tattttttac
    57361 agtcatctat gacaggttgt aaatactatg gaacatcata tggcgttgtc attttcttgt
    57421 caactatttt tcctattcat gtttttataa aaaaacatat cgttttcttg tatgattaaa
    57481 tcaccacaaa ataaacaact gagagaacga tatgctttat gaatggttct atcaaaaaaa
    57541 ttctgagatc aatagacaaa aatttgatga ttacagaggt ctcttacgaa accttacaga
    57601 agaaaaaaac attgatcgtt gctgcagttc tcttccctgc tccatgtgtc tgtagaaatt
    57661 gtggttctgc tgtggtagat ggaaatagga aattaatggt ggtgaaaaac aagaagaagg
    57721 aaaccattgt ccactttgaa taatataatc atatgccaat ggttatacgc ctaaaaaagc
    57781 agcgctatac ctgtaaaaac tgtcgaagcc attggaacgc tcaaagttat tttatccgtc
    57841 caaggcactc gatttcaaat catgtcagac ataaaatcac ttctttactg actgaaaaag
    57901 tgtcgttatt ttttatttcg aaaagttgtt aggtatcttt gacaaccgtt attcgcacat
    57961 tgaaagagtt gagaagctat ttaccaaagt cttccaaaag aattctgtct tgagtgttga
    58021 gggttgtgaa tttcgttctc acgtttccgt tgaggataaa ctgagtttta tttccgcgga
    58081 tggcgagaca gaaaaattaa tcgagaaaat ttacctacac aaaaaattcc tcgattaaca
    58141 aactatttcc ttagctgcac taatcctaaa gaaatagaat tcttagttac agacatgaac
    58201 gccacctact ttcagctcac caaacatgtt ctaccaaatg cgaaattggt gattgatcga
    58261 ttacttggtt tttccacgcc tttcaaggag gcgtaacctt tattcacgag ttggttgaag
    58321 ctttccgaga caaaagaccc gacttgtttt tctccttatt gacaaagagc cattaaaact
    58381 agagaaaaaa ttacaactga tcgctgatta tttgtagaaa gaaaatcaaa gtattaccca
    58441 ataaacttga gtcattaggc aaaaaacact gcgaaactca agaatgattt tcgcagtgtt
    58501 tttgtatatt ttttattaac tagtattact acaaaggttt atttttcact tctcaacgca
    58561 gcacaaaatt gtctttactt atttactggt tgggttcaac cttctctact ccgatactaa
    58621 tatttgtttg tatacccctt ctaaaatcgg tagtttccat tcaattgatg ggtactagtt
    58681 gattttaaaa actatgctta ttcaattttt tattttagct catatatttc gtttctttct
    58741 aaattttata ctgatgaaaa caagtagcac acccaatatt gacaatataa actggctaat
    58801 gatggtttct ccagtttttg gaagatgctt atttccactg cttgttggat tgtttcctct
    58861 tatatctgag ctatcagcaa cttttctatt ctcttttgtt aaaaagatcg ccacttcttg
    58921 ttctttttcg atcttgaaag ttactggtgt cgcatccaat tcataccccg ttggcgcttg
    58981 agtttctacc agctgatatg ctcctggtgc taagccatct atcgccagtt ttccatctgc
    59041 tcctgtggtt agacctgact gcagaacggt tccattggca tcttgtaact caaaaacagc
    59101 tccttgcagg acttctccgc tttggtcatc gatctttgtc aacacgacac cgcctggtgt
    59161 aagtcgattt tctttcgtca attctaccac cgctgtctga cttctttcga tctcaaactc
    59221 gattggtgtc gcatccaatt cataccccgt tggcgcttgg gtttctacca gctgatacac
    59281 tcctggtgct aagccgtcaa tcgccagttt tccatctgct cctgtggtta gacctgactg
    59341 cagaacggtt ccattggcat cttgtaactc aaaaacagct ccttgcagga cttccccgct
    59401 ttggtcatcg atctttgtca acacgacacc gcctggtgta agtcggtttg ctttcgtcaa
    59461 ttctaccacc gctgtctgac ttctttcgat ctcaaactcg atcggtgtcg catctaattc
    59521 atacccc
//
LOCUS       DARPZF010000012        56389 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.012, whole genome shotgun sequence.
ACCESSION   DARPZF010000012 DARPZF010000000
VERSION     DARPZF010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56389
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.012"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            330..1175
                     /locus_tag="SLE65_001026"
     CDS             330..1175
                     /locus_tag="SLE65_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEI8448335.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="SLE65_001027"
     CDS             1456..2676
                     /locus_tag="SLE65_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HEI8448336.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="SLE65_001028"
     CDS             2673..5393
                     /locus_tag="SLE65_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEI8448337.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="SLE65_001029"
     CDS             5377..6321
                     /locus_tag="SLE65_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEI8448338.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6390..7400)
                     /locus_tag="SLE65_001030"
     CDS             complement(6390..7400)
                     /locus_tag="SLE65_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEI8448339.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7580..7924)
                     /locus_tag="SLE65_001031"
     CDS             complement(7580..7924)
                     /locus_tag="SLE65_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEI8448340.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7917..8351)
                     /locus_tag="SLE65_001032"
     CDS             complement(7917..8351)
                     /locus_tag="SLE65_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEI8448341.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8489..9226
                     /locus_tag="SLE65_001033"
     CDS             8489..9226
                     /locus_tag="SLE65_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8448342.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9219..10430
                     /locus_tag="SLE65_001034"
     CDS             9219..10430
                     /locus_tag="SLE65_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8448343.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10634..11416
                     /locus_tag="SLE65_001035"
     CDS             10634..11416
                     /locus_tag="SLE65_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEI8448344.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11486..12148
                     /gene="trmB"
                     /locus_tag="SLE65_001036"
     CDS             11486..12148
                     /gene="trmB"
                     /locus_tag="SLE65_001036"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEI8448345.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12246..14000)
                     /gene="ade"
                     /locus_tag="SLE65_001037"
     CDS             complement(12246..14000)
                     /gene="ade"
                     /locus_tag="SLE65_001037"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HEI8448346.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKEHLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14132..15061
                     /gene="tadA"
                     /locus_tag="SLE65_001038"
     CDS             14132..15061
                     /gene="tadA"
                     /locus_tag="SLE65_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEI8448347.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15018..16067
                     /locus_tag="SLE65_001039"
     CDS             15018..16067
                     /locus_tag="SLE65_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HEI8448348.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16064..16342
                     /locus_tag="SLE65_001040"
     CDS             16064..16342
                     /locus_tag="SLE65_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEI8448349.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16317..16787
                     /locus_tag="SLE65_001041"
     CDS             16317..16787
                     /locus_tag="SLE65_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEI8448350.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16804..17106
                     /locus_tag="SLE65_001042"
     CDS             16804..17106
                     /locus_tag="SLE65_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448351.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17123..17494
                     /locus_tag="SLE65_001043"
     CDS             17123..17494
                     /locus_tag="SLE65_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HEI8448352.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17466..17825
                     /locus_tag="SLE65_001044"
     CDS             17466..17825
                     /locus_tag="SLE65_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448353.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17997..19004
                     /locus_tag="SLE65_001045"
     CDS             17997..19004
                     /locus_tag="SLE65_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEI8448354.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19029..20213
                     /locus_tag="SLE65_001046"
     CDS             19029..20213
                     /locus_tag="SLE65_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEI8448355.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20650..22233)
                     /locus_tag="SLE65_001047"
     CDS             complement(20650..22233)
                     /locus_tag="SLE65_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEI8448356.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22811..22954)
                     /locus_tag="SLE65_001048"
     CDS             complement(22811..22954)
                     /locus_tag="SLE65_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HEI8448357.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23177..23656)
                     /locus_tag="SLE65_001049"
     CDS             complement(23177..23656)
                     /locus_tag="SLE65_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEI8448358.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23729..24013)
                     /locus_tag="SLE65_001050"
     CDS             complement(23729..24013)
                     /locus_tag="SLE65_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448359.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24091..24285)
                     /gene="ssrS"
                     /locus_tag="SLE65_001051"
     ncRNA           complement(24091..24285)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="SLE65_001051"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24357..25643)
                     /locus_tag="SLE65_001052"
     CDS             complement(24357..25643)
                     /locus_tag="SLE65_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEI8448360.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKSAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25781..26452
                     /locus_tag="SLE65_001053"
     CDS             25781..26452
                     /locus_tag="SLE65_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HEI8448361.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26418..26906
                     /locus_tag="SLE65_001054"
     CDS             26418..26906
                     /locus_tag="SLE65_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEI8448362.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26919..27866
                     /gene="prmA"
                     /locus_tag="SLE65_001055"
     CDS             26919..27866
                     /gene="prmA"
                     /locus_tag="SLE65_001055"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEI8448363.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27867..28631
                     /locus_tag="SLE65_001056"
     CDS             27867..28631
                     /locus_tag="SLE65_001056"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEI8448364.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28864..31077
                     /locus_tag="SLE65_001057"
     CDS             28864..31077
                     /locus_tag="SLE65_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEI8448365.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31088..31534
                     /locus_tag="SLE65_001058"
     CDS             31088..31534
                     /locus_tag="SLE65_001058"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEI8448366.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31705..32964
                     /locus_tag="SLE65_001059"
     CDS             31705..32964
                     /locus_tag="SLE65_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HEI8448367.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33053..34000)
                     /locus_tag="SLE65_001060"
     CDS             complement(33053..34000)
                     /locus_tag="SLE65_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEI8448368.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34394..35686
                     /locus_tag="SLE65_001061"
     CDS             34394..35686
                     /locus_tag="SLE65_001061"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEI8448369.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35701..37470
                     /gene="aspS"
                     /locus_tag="SLE65_001062"
     CDS             35701..37470
                     /gene="aspS"
                     /locus_tag="SLE65_001062"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEI8448370.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37579..38454
                     /locus_tag="SLE65_001063"
     CDS             37579..38454
                     /locus_tag="SLE65_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEI8448371.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38720..40603
                     /locus_tag="SLE65_001064"
     CDS             38720..40603
                     /locus_tag="SLE65_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEI8448372.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40678..40962)
                     /locus_tag="SLE65_001065"
     CDS             complement(40678..40962)
                     /locus_tag="SLE65_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEI8448373.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40952..41686)
                     /locus_tag="SLE65_001066"
     CDS             complement(40952..41686)
                     /locus_tag="SLE65_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEI8448374.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41815..42438
                     /locus_tag="SLE65_001067"
     CDS             41815..42438
                     /locus_tag="SLE65_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEI8448375.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42630..43751
                     /locus_tag="SLE65_001068"
     CDS             42630..43751
                     /locus_tag="SLE65_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HEI8448376.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43758..46886
                     /locus_tag="SLE65_001069"
     CDS             43758..46886
                     /locus_tag="SLE65_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HEI8448377.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46905..50099
                     /locus_tag="SLE65_001070"
     CDS             46905..50099
                     /locus_tag="SLE65_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HEI8448378.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50245..50952)
                     /locus_tag="SLE65_001071"
     CDS             complement(50245..50952)
                     /locus_tag="SLE65_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEI8448379.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51717..52115
                     /gene="spxA"
                     /locus_tag="SLE65_001072"
     CDS             51717..52115
                     /gene="spxA"
                     /locus_tag="SLE65_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEI8448380.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            52447..53100
                     /locus_tag="SLE65_001073"
     CDS             52447..53100
                     /locus_tag="SLE65_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEI8448381.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            53326..54324
                     /locus_tag="SLE65_001074"
     CDS             53326..54324
                     /locus_tag="SLE65_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEI8448382.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            54500..56308
                     /gene="pepF"
                     /locus_tag="SLE65_001075"
     CDS             54500..56308
                     /gene="pepF"
                     /locus_tag="SLE65_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEI8448383.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        18555 a         9728 c        11686 g        16420 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt tattttgatg aatcagttgt ttcttcagtt
     6421 gaagattctt ttgttgaatc agttgatttt gtgtcagaac tctttgttga agctgtagtt
     6481 tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg cactcaacac attttcaaag
     6541 gcatcatctt tgatttttac atttgcatct tttaattctt caccgattac tttagttgtg
     6601 aatgcattgt cacttagttt agtttcagta gcgatatctt ttagttgatc tttgtattta
     6661 tccatgtcat tgcctttatt ttggtttttc accattttga caacgtagta ttctgtcgca
     6721 taagaagtag gatttgttgt agtaataaca tcggagatct caccgtcttt caatttgaaa
     6781 gctgcttctt ttacttctgc aggaatagtt gttgtcgttg agtcgaattt aactttaccg
     6841 ccatcttctt ttgtctctgt atcagttgat ttgtctttgg ctaatttaga gaaatcatct
     6901 ccatcatccg ctgatttttt cacatctttt gcttcatctt cacttgataa tttgatgatt
     6961 tgtgcttcta cttctggatg gaaagatttc caagcagttt tcaaatcgtc atctgtaata
     7021 tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt tacgaatata ttctttataa
     7081 gtatctttcg tatatccagc agcttctaat tgtgattcaa aagtatcacc taatgatttc
     7141 gcttgtttgt cgtattctgc atccacttgc ttatcggtta ctttatcgcc atatttgtta
     7201 ttgaatactt tataaatgat catccgttgt actaaggatt ggttcgatga ttcaagtttt
     7261 gcttcatcat agaaatcaga tacagtgatc gttccgcctt tcatcgttgc gatatcttta
     7321 ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca acgcactagt agctgccaaa
     7381 ataattgatt tttttttcat taaaatttgc actcctgtaa ttagttatta tttttatata
     7441 ttaactatac catatcccat ttcctttaaa aacgttgtcg tggtagtttc aaacaaaatt
     7501 caaaatttca tcacattcct aggaaatacg caaacttttc tcacttatat agttaaatct
     7561 gttgagaaaa taatcattat tatatttgtt caggatactc tggcagatca gcttttagtt
     7621 tttctacttg ttcattgatt tgtgtgatac gtggttcggc ttggaattta aaatcttcga
     7681 tatctttttt gattgcttct tggaaagcag gaatcacaga ttcagctgtt tcttttgttt
     7741 cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa atcatttgtc agagttgttg
     7801 cttcttccaa ttcttcgatc agtttctttc ttgtttcatt cccgctcctg ggcgccaata
     7861 acagacctcc gacagtgcca gcagcagctc caaataacag tcctttgaaa aagtttttaa
     7921 tcatcgcagg acacctgctt tacgattgtt tcttgaatag cttttagttc ttccgatcca
     7981 taactatctt gatgattgac aaagtgaata gaaaaatcat cctctttgct gtagcgaggg
     8041 actaaatgga tatgtgaatg aaaaacagat tgataggcta gttcacggtt gttattcaag
     8101 atattaagac ctttcatttc tggaaaagct ttttccaatg cttgagcaat cttaggcaca
     8161 cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa aaatatctgc tacatgacgt
     8221 ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga tgtctaaaaa agcatagacc
     8281 ttgtcgtctt catatatttt atagcttggg atttcttgat tgatgatttt gcaaaaaata
     8341 cagttttcca tataaaacat cctttctata aagaataaat acttcagctt aactttacca
     8401 taagttaaag ctattgtaag gaaaaaaaca aaataccgtc attttcttcg tggtataata
     8461 aataaaaata aatggcggag gaaaaagaat gagtttaatt atcgatcatg tcacaggggg
     8521 gtacggacat ctccctgtgt taaaagatat cagtttcgat gtacagcctg gagagatagt
     8581 agggttgatt ggactgaacg gagcagggaa aagtacgacc atcaagcaca ttatcggtct
     8641 gctggaagct tcaaaaggaa cgatagaaat caatcatcta tccttaaaga aaaatacgga
     8701 agaatatcgc aaacaaattg ggtatattcc agagactcct tctttatatg aagaattgac
     8761 attgagagaa catatcgaag tcactgcgat ggcctacgat atacctatgg atatagcaat
     8821 gaaaagagca gaaaagttgt tggagacttt tcggttatct aatcgtcttg actggttccc
     8881 agctaatttt tcaaagggaa tgaaacagaa agtgatgatc ttatgcgcct ttttgatcga
     8941 gccttcttta tatatcatcg acgaaccatt tttaggcttg gatccactag ctatcaatgc
     9001 attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc ggtattttga tgtctacgca
     9061 tattttagct actgcagaaa aatattgtga tcgttttgtg gtcttacata acggagagat
     9121 acgagcagac ggttctcttg agatgttgag aaaagaattt cagctgccgg attcttcttt
     9181 ggacgaaatc tatattgctt taacaaagga gcaggcacat gagtagtttt tttcaaaaac
     9241 gtttagcaag acatcaaaag aaaatgatga aatatatgcg ttatgtattg aacgatcatt
     9301 ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt atattattct aattggttga
     9361 aaaccctgca gccaccgttt gcaattggag ggctcataat ctctgtattt tggatgctct
     9421 gtttattcgt gggtaagatg gctacttttg cagaggcagc agatattgtt tttttacttc
     9481 ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt tcgctattct tgcatttttc
     9541 cgttgatctt tttgatattg gcatgcggat tggccatgcc attagtggtg gttagtacgg
     9601 agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt atggagtttg aaattcagtc
     9661 atctgcaaat caagagagca gaattgtttc gactagatca acaagttatt cgttattgga
     9721 aattaggctg gtttttttct tctctgatct ttttgtttct atcattttat tggctaatat
     9781 gggcaggaat agcaggtgca ttagtacagg caagtctata ttactggttt ttgtggaagc
     9841 aacaagaaaa aggattggat tgggagaaaa tggtgcatgt agaagaacat aggttgcatc
     9901 agatctatca atttatcaat ttattcacag atgttcctga aattacggca aagatcaaaa
     9961 gaagacgcta tttggatcct atattgactc atattaaaag agaatcaaaa aacacttatc
    10021 tttacttgtt tgcaagaaga ttggcaagag gttctgattt tagtggtctt tatttccgat
    10081 tagtaattat aggtgggtta ttgattgccg gagtagtcga cttttatttt agtctgatta
    10141 tcggtttctt atttttatat ttgatcggtt tccaactgtt acctttagcg aaccagttcc
    10201 gctatatggt tctcgttcag ctttatccaa tccataagaa tcagaagaag caggcgattc
    10261 agtatctact cacatgggta ttaattatcg cgtcggttat ttttggtttg attgctgcag
    10321 tcgtattaga tgggcagcag cgatgggttc cgctagcggc ttatttgatt gttactatgc
    10381 tctttgttaa actatatgta ccaactcgtt tgaagaagat gtcagactga aaacaaagct
    10441 gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca gtaagaatgc tgttcgttct
    10501 attttttttg agaaaagctg gttttttgaa tggcaattaa atgaaaaaga acgtatatgt
    10561 gcttgacgtg tagtgttcag gcgactagaa taataagtac tgcaaaacaa agagtaagag
    10621 gacgggagaa tgcatgatgg agtttcagtt agaccaagag tggcggttac gtcccatcaa
    10681 aggcgacaca ggaaaaacat acataggcat gcgtgatgag gacaaagtct ttattaaacg
    10741 aaacacgact ccgatgttgg ctgctctttc aagggaagga attacaccaa aacttgtttg
    10801 gacaaaacga acggggaatg gcgatacttt gacagcacaa gagtggctgg aaggtcgctt
    10861 gctgactcct aatgagattg gtcaaagaaa cgacgtgatt gatgttttgt accatttaca
    10921 tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt ggtcgtgtca tgacgccgga
    10981 gaagatgctg caaaaatatg aaaaagaatt accggaagaa ctccagaaaa atcaatttct
    11041 gcaaattgtc catcgttttc ttcgtgagca gatcccgtca atagataagg aaaacttatc
    11101 agtagtacac ggagatgtaa accatcgtaa ttggttagta tgtaaaaatt atttatatct
    11161 agtcgattgg gattcaatca tgtttgcaga ccctgcggtg gatattgcaa cgattttagg
    11221 aaattatgtg ccactgtcta gctggaatca gtggctgatc agttatggca tacgcccgac
    11281 tgacgaaatg cttgaaaaat ttcattggta tgcggccatg aatttgctcc aagaaatcac
    11341 cagatattgc aaacgtgaag atcatcgacg gatgaacgaa gaaattttac aattaaaacg
    11401 aattttcagt ggctgaggtt tggcccaaac tctgcggaga tttggccaga cctttttaat
    11461 tagaggaaag gaatggagat aaataatgcg tgtccgaaat cgtccgggag cagcggaaat
    11521 gttagcggct cacccgaatt ttgtaattag tgatccaaca ttgtggaagg gaaaatggaa
    11581 tgaattgttt gaaaacgatc atccaatcca cattgagatt ggtatgggga aaggccagtt
    11641 catcactgga atggcaaaag cccatcctga aatcaattat attggagtag aaatgcaggt
    11701 cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa ccgcttccta acctgaaact
    11761 tctacatgtg gatggatcag cgttgacaga gtatttcgct gacagcgaag tagatcaaat
    11821 ctatctgaat ttttccgatc catggccaaa aaaacgtcat gaaaaacggc gattgacata
    11881 taagactttt cttgctgtag atgaacagat tcttcgtcca aatggagaaa tccatttcaa
    11941 aacagataat caaggattgt ttgagtattc tctggcaagt ttttctcaat atggcatgat
    12001 cctcaaacag gtatggttag atttacatca aagtcaattt gaaggcaata ttatgacgga
    12061 gtatgaagaa aaattttctt caaaaggtca acgtatttat cgagtagaag ctcaatttca
    12121 agataagacc aaaaagaaaa gtctgtgaaa ctaactttct gctttcataa aaacattaat
    12181 atccataaat aaatcccaga aaatgaacat tacagatgta atgtattttc tgggatttat
    12241 ttgatttaaa atgtatttat ttcatcggtt tttccacaag gtggaatcaa ttggaagcga
    12301 gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg gtatgacaga taatgttaag
    12361 aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc ctagttgatg tgctttagtt
    12421 attaattcat tcaactgttc atagacgatc gaaaaaggtt cctgtgtcat gattccgcct
    12481 ataggaagag aaacacaagc tatttcctgc tgtttgttga caacggtcat cccgccacct
    12541 ttttgaatca aaagattagc agcatacagc atatcctcgt cgtttgtccc aacgacaact
    12601 agattatgcg agtcatgggc aatcgttgtc gctatcgctc cttgtttcag ctgaaatcct
    12661 ttcactatgc ctaatccaat gtttcccgtt tgatggtgac gctcgatcac cgcaatcttt
    12721 aattggtctt tttcgattga aggaatgaat cgttcgcctt gtcggtccac tttttctacc
    12781 aaatctttag tcactagact attcgggata atttcgatca catgggcttg tgaagaagaa
    12841 agaagcagct ctaacgaatg tggatttaat ggttgagcgt ttagttttgg cagacaacac
    12901 gtatatgaat ttgaatgatc agcaaataaa tggtcttgga gttgcccaga ttgaacaact
    12961 aatgttccct tatagaaaac ttcatgaatt ggcagcttgg taagatcgtc tgttaagaag
    13021 aaatcagctt gatacccagg ggcaatcgca cctagtgttt tcaaatcaaa acattctgct
    13081 gcattcaatg ttgccatctg aatggcttgt aatggatcga ttccaagtgc aatagcttga
    13141 cggacgatat gatcgattga tccttctttt actaaatcat tgatcagttt atcatcggtg
    13201 acaaagaagc atcttcttga attttcaggt gtgatcgccg gtagtagcga tgccagatct
    13261 tttgcaacgg tcccttctcg aaccattaaa tacataccaa gatccaaatg ttctttagct
    13321 tcttttgcag ttgtagcttc atgatccgtc cgaatacctg ctgcaggata aacatttaac
    13381 tcttccatgc cgataccagc tgcatgcccg tcaatttttt tcttatgctg gtgcatcaat
    13441 tggatctttt ctaggatgtc tgtttcatta tttgctactg cttgatagtt catgacttca
    13501 gctaagccta aaacttcggg tttttgtaaa aaaggggcta atttttttgc atttaaattt
    13561 gcaccattgg tctcaaaagg ggttacaggt acacaagaag gtagcataaa aaagatattc
    13621 atgagtgttt gtcttgcatc ttctatcata aactcaagac ctgtactccc agcaatgttt
    13681 cctatttcat ggggatctgt cactacagta gtaactccat gaagcaagga tacttttgaa
    13741 aattcgcttg gtgataaaag tgagctttcg atatgcacat ggccatcgat gaatcctggc
    13801 actagatatt gcccattagc attatgtacg ctttttcctt cgtattcacc gattcctacg
    13861 atcattcctt cgcagattgc tacatctttt tccatgattt ctttcgtaaa gacgttgacg
    13921 atcttagcat gcttgatcac taggtcagca ggcttttttt tacttgctac ttcgatatat
    13981 ttccttaatg ttgtttccaa tggagtgcct cccaagataa atttttataa gtataacata
    14041 aattcggttt ttgccaatat ttttttgtaa attcatttta tttgaaacaa aaagatcaaa
    14101 aagacgtatg ttttttgtgg aggggagaat aatggaaata aaacgattat cggatcaaat
    14161 gataagtgaa agttttgcca aacatgccca agacgtatat atattgccag cttcagaagt
    14221 attttacatc tattttcgct atggaaaaaa acgaacattc tggaagaaag tctcttcggc
    14281 agatggacag caactgatct caagatttaa gtatttggga cagatggata tcggagaaaa
    14341 aagaaaagct cagttaggtg catttactta ttctttagaa aaacaggaag ttcgtctgcg
    14401 gttgtcttct gtaggagatt accttcaacg agagagttta gtgattcggc tattatacgg
    14461 tacttttgaa acaccccatc gttgctttag ttctcgagat tttgcaacta ttttacagaa
    14521 aaccgtcaga cgtggattat accttttcag cggaccagtc ggatcaggca agacttctct
    14581 aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt actatcgaag atcctgtaga
    14641 gatagaagaa ccgttttttc tgcagctaca gatcaatccg aaaatagcac agacttatga
    14701 tacacttttg agactcgcat tacggcatcg tccagacttg ctaatcattg gcgagataag
    14761 agatgaatca actgcacatg ctgcggtaag agcagcacta acagggcacc gggtttttgc
    14821 aaccgtacat gcacgcaatc ttgaaggtac attggtcaga atccatgaac tgacaaagaa
    14881 aaaagaagag ctatctgaat gtttagctgg tgtcatttat caagaacttt tggaagatgc
    14941 caatcaccat ccttctgttt tatggagtta tcaatttatg gaggaagaat cagtaaaaaa
    15001 atcatgggag gaaagttatg aagaagctca ggaaaatatt tggcagtcag aactattcta
    15061 aaggattaac aagaagccag caaaaccagt ttgcacaaac catgggagaa ctgcttttat
    15121 ctggttttag tctgcaagaa tccctttatt tattactcac gatccgttcg tttccacctg
    15181 ttattttggc aaatatccaa catcagctaa aggaagggca agcgtttagt gaggtacttt
    15241 cgcaaatagg atatggagca gagcaactgg tacagatcga gttagctgaa cgtcatggga
    15301 atctgccgac aactttgttg gaaattgcca aacagtttcg gcttgttgaa ggatttcgca
    15361 atgatttgaa aaagctgctt gcatatccga tgctattgct cacctttttg ctaggtatct
    15421 tgtttagtat gcggttgttc gttttgcctc agcttattgg ttcaggaatg gtcatgcaag
    15481 agcattgggg tattcagctg atacaagtct ttcattggta tgttctacta ttcatcctag
    15541 cggttactct attggcttta ctagtaaggt atcgtctgat gaagttgtct cctgttgatc
    15601 agagtgaatg gataagcaga caattattga ttggaccgat atattccttg tatcaatcgg
    15661 cttatttgtc actagagatt ggaaagcttt ttcatgaagg tttcgaatta aggcaaatca
    15721 tagtctgctt aaaggaaacg aaacaagaaa gtctgattca gcatcttgcc tctaagttga
    15781 ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt ccagaattat cgttttctat
    15841 cagaagaatt cagtaaaatt gttttacagg gagaggcaaa gggaagttta ggtaaagaac
    15901 tgatttttta cagcgaatgg acaagaaaac agcttttcaa acgtcttcat cactggatgc
    15961 attttattca gccaatcatt tttttgggcg tagcggcttt gattttatta gtttatgccg
    16021 ctgttttatt acctgtttac ggaagcatag aggaggtttt gccatgaaaa agagaaaaat
    16081 atcttattat agcggtttta cattgatcga aatgctaatc gtcttactga tcatcagtgt
    16141 attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg aatcatgtag accaagaaag
    16201 tcgtgaagcg atcatccagt tggtagacac acaaaaagag ctctatgcgc ttcaaaataa
    16261 tggaagagtt cctactgtgg aggaattgtt gaatgaaggc tatatcaaac gagaacatgc
    16321 agaaatctat cagcggcctt gaaggtaagg ttttagcatc aggatatacg ttgtttgaat
    16381 cactcttact gattttatta cttacaacga tcctttcttt tccagttctc gcattttctg
    16441 catggaagaa tgaattggca gtctatcaat ttttcggcca atttgaaaaa cgaatctatt
    16501 ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg cttttattgg aatagtgaag
    16561 agaatcaaat catttttcat gttccgaatc cagataaaat aaattgggaa gtattagata
    16621 ttcctgatga gattaccttg aaacgccatg cttctattac ttttgctgct agaaccggga
    16681 atgaaagttc actaaaagct tatcaatttt attgggaaga aaaagagcgg acgattacgt
    16741 atcaattcca gatagggagt ggtcgctata caaaaagaat tgaataaaac aggatttgtt
    16801 ttgttggagt cccttacagc gcttatgatc gcttctgtct gtgtctactt agtgagcttt
    16861 ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg aggaactgct atttattcga
    16921 atgatttatg aagatatcaa gacgcagcgg atgtatcaca aaagaccaga gcgaagggaa
    16981 gaaatgatcc catacgatat ccaaattgtc gataataatg gagtaatcga aaaagtgttt
    17041 gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa gtaattccag catttacgct
    17101 gattgaatgt ctaattggac tgatgatatt gagcagtcta ttgctcacat tcaatctttt
    17161 gattcagcaa accatccaag taagtgaatt tttgcagcgt aaagatcaaa aagagtggct
    17221 aatattttta gcacaattag aagaagaact caagagcagt cacaatgtct ctgtgaaaaa
    17281 tcagcaactg cactacacga tcgaggataa acagtatatc atcgaaagat atcaggcaat
    17341 gatacgtaaa agaagaactt ccggcggaca tcaacctatg ttaacaagta tcactgagct
    17401 tcaattattg gaaaaagaac acacaatttc tttttatgta cactttgaaa atggagaaga
    17461 tggatatgcc atatggacaa aaaacgatca gtagaaaatg ttataagggc tctattttat
    17521 tttctgtctt gcttttattt cttttatgta cgtttttatt gatggcagca ttagaaagct
    17581 accgtttgtc aatggatctt aatatacgaa tcaaaaatta ttatatagca aaaataatga
    17641 agcagatggc tttatcggaa cagtctacgc ttgccgaaag ttcggaagga gttttttact
    17701 acacaactgg atctgtaaca tatcagtggg tacaacagtc cctattctta gaggtggaag
    17761 tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa tgatacagat actagtacag
    17821 aatgatggaa tgttcgtgaa aacgccctct tttctgttat aacactgttt ttaataaaaa
    17881 aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat tgaaattttg tcaattgttc
    17941 gatagaatta aacaggtgaa aaaattgtta taatatatct agaaatgagg tgcaccatgt
    18001 taccagaaaa aatggaacaa gggtttaatc aaaacctgga agctattcag cttttacaga
    18061 atgcattggg aacttccttt ttagaagcct atgtcgaaaa tgcagaaaat ttaatagatg
    18121 attatcaagt acgtgtggtg gatggagtgc cgacaaaaga gacaacgcaa cggatcacag
    18181 ctctttatga agagttgaag aaactttctt tcgagccaga agaatggcgc agactgtctc
    18241 aattactttt attgaagggc agccagacag aacatttgca ggcgaaccat caactcactc
    18301 ctgatagtat cggtttttta tttgtttttc ttattgaaca actatacaca aataaaaaag
    18361 caccggttaa gattctggat attgcggcag gaatgggcaa cttgttatta acagttcttt
    18421 taaacctatc gaatgcgggg taccaaacag aaggaattgg tgtggatatt gatgatacat
    18481 tgttggctgt cgcagcttct acaagtgatt tgacacaagc aaatgttcaa tactttcatc
    18541 aagacgggtt gcaggaatta ttaatagatc ctgtcgattt tgcaatcagc gatttgccaa
    18601 tcggttatta tccgaatgac gaaaaagcaa aagagttttt aacaagtacc gaagaaggcc
    18661 atagttatgc acatcattta ttgctagagc aatcaatgaa atatgtgaag ccggatggtt
    18721 ttggtttgtt tttgatgccg agtggatttt tagaaacgga tcaaagtgaa gaaatcaaaa
    18781 aatggtttaa agaagaaggt tatcttcaag gaatgattca attgccagat gaattgttcc
    18841 gtaataaaca atcgcaaaaa agtattttga tcttacagaa aaaaggacca caagcacaac
    18901 aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa agaaccagag aaggtgacgg
    18961 aatttttcaa cgagtttaaa aactggaaat catctgctct gtaatcattc aacgagaagg
    19021 agagtcatat gtctaaaaca attgcaatca atgctgggag ttcaagtttg aaatggcaat
    19081 tatatcaaat gccagaagaa accgtagttg cgaaagggat cgtcgaacgt atcggtttac
    19141 aagattctat ttttaccatc aagtacggcg ataatcaaaa attcgaacaa atcatggata
    19201 tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca gttgattgaa ctgcaaattt
    19261 taagctctta tgatgaaatc accggagtag ggcaccgtgt tgttcacgga ggagaaactt
    19321 atggggattc agtagtgatc gatgagaaag taatggaccg cattgctgaa ttagcagaat
    19381 ttgctccttt gcataatcct gcaaacttaa tggggatcaa agcgtttaaa aagattttac
    19441 ctgacatttt gagtgtggct gtattcgata catctttcca ctcaacaatg ccaaagcaaa
    19501 attatttata tagcttaccg gtgtcttatt atgaagattt caaagtaaga aaatatggct
    19561 tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc aaaattattg aacaaaccga
    19621 tcgaagaact aaaaatcatc acttgccact taggaaatgg tgtatcgatc acagcagtcg
    19681 atggaggtaa atccatggat acttctatgg gattcacacc attagctggg gtgacaatgg
    19741 gtacacgttc aggtgatatc gatccagctg ttctcccata tttaatggaa aaattagaga
    19801 ttgatattga tgaaatgatc aatgttttga acaagaaatc tggtctgcta ggcctaacag
    19861 gattgtctag tgatatgcgt gatcttgaaa agaactatga aaaagaacat attcgtttag
    19921 cttatgacat tttcgtggac cgcatccgaa aatacatcgg cggttatgtg acaacgatga
    19981 atggtgttga tgcaattgtc tttactgctg gtatcggcga gaatgacgga catgtacgta
    20041 gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat cgatccagcg ttgaatgaat
    20101 tgcgtggtga agaagtagat atctctacaa aagaatcaaa agtaagagta ttagtgatcc
    20161 caacagatga ggaactaatg attgcccgtg atgtggagcg tctgcgcggc taagccaaag
    20221 cattcgttag gataaaagat gaaacgcatg caagagggaa ttcttgcatg tgtttttttt
    20281 gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc cttctttttt acaggatctt
    20341 cttagggaat tttgcttgga aaagtggtca aaagggaaaa gactggcatt ttatttattg
    20401 attttcagga aaatcccaat attttatttt cattcatctt tataagggac attacatatg
    20461 taaaaagaaa aaacattttt agatcagcct cgtgggctgt cgactttatt cttcgcttta
    20521 tgtttagcta gaaaaccgat ccgaaacatt cattgatcga ataataaaaa cttgattttc
    20581 cacctgtact ttgcctgaat cgtgaaagca caggtatgaa aatcaagttt tttgttgcga
    20641 aaaaacgtcc tagtcaatca gttggccgag cggctggcgg ctgatctgct cctgatcaat
    20701 aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg tcatggctga ctgctaggag
    20761 cgttccttga tagtcttgca gcatttcttc aatttcttct cgagcatagc tgtcgaggtg
    20821 attggttggt tcatccaaaa tcaggacgtt gattttttct aaaaagagtt tcagcaacgc
    20881 caaacggatt ttttcaccac cggataaatc tttgatccgt ttacccacat cgctttgata
    20941 aaagccactt ttggctaatt gccgtcgagc gacttcttcg tttccagtca atgtgatggc
    21001 gtaagccagc aaacggctat cgggatcggc aaactgcagc tgctgcggca aataaccgat
    21061 ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc ttttcctcac cgagtaataa
    21121 tttgagtaag gttgattttc ctgcaccatt gtcgccgatg atggctaaat gatctccacg
    21181 atagactgca aaactgctgt ctttgaatag tacttgatca gcgtactgct ggtgcaagtt
    21241 ttgaatgatg aaaacttctt tgccagattt tccaccatta gacaagcttt gcagccgatt
    21301 tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc aggcggcgtt ccagttcttt
    21361 ggcttttttg aagaaggact cattgtctcc ttcatgtgcc cactgacgaa aacgacgaat
    21421 catgactttc aaccgctgga cttctttttg ctgcagttcg taattttttg tcagctcagc
    21481 caagcgagct tctttcaaga ctcgaaaacg gctgtagttt ccgggatact caatcaatgc
    21541 accttcttcc agttcccatg tttttgtggt gacttgatcg agaaattgcc gatcatgaga
    21601 aacgaccaga accgattttt ttgtattctg taaatagttt tccaaccagc gaatactgtt
    21661 aagatctaaa tgattggtcg gttcatcgag taaaagtaaa tcggcatcgg ctgctaaaat
    21721 tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt tctgttaacc gtgcttcctg
    21781 acggtgtgga atccctaagc cttgcaagat cgctgcaatc cggtcttcta atacgtaacc
    21841 gcctagttct tcaaagcgat gctgcagctc accgtaacgg gccagacact tctctaagtt
    21901 tgtatctggt tctgtcatca atgcttcgta gcgactcatt tgctgtttga ggtcctgtat
    21961 ctcagcggca gaatggagca agtagtggtt gacggtcgct tcggaaactg taagttcttg
    22021 ttcgaccgtc ccgatcttta agcctttttt gcgactgata acaccgctgt cgacaccttc
    22081 tctgccggtc aagatttgta aaaaggttga tttgccagtt ccgttgatac cgactaaggc
    22141 aattttttca ccagcttcaa tttgacagga taaatcctca aataatggat tcccgccgat
    22201 tgttttttta atagaaattg cttgtatgat catgatctct ctccttgaga ccactcaaaa
    22261 aggccatggt tatccatggc ctgtgttatt taaactcaga ttatcatgag aaaaatacct
    22321 tgagatggcc attgatttta cgtgaattca actgttttgg acaaacttgt cccgtcaaca
    22381 gcaactgtaa aaccaattgc atggctaaat gcgatatggt atcgttggta attttcatta
    22441 cttgttattt tagtcatgcg catcatagta ttttccctcc ttcgtgtagt tgtcttttcc
    22501 agtgtacctg aaagtgtcag aaagttcaac tagcgctgac atttacttaa tatttatcga
    22561 tgtgtaattc tgtcagagag ctttttttat ctgactgagg gtaatgtctc gtggaccaca
    22621 tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca tatggtgttt gataaaaaac
    22681 tttgtctaca tgacttcctt ttgccatttg cttaataccg ttgcattaaa cagctcttct
    22741 ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt gtggttgcaa tggcaagcgg
    22801 tagcctttca tcaattcttg aatgatttac cgaatgtagc acttgccttc tcgcggtacc
    22861 cgaacccgaa ataaaatttt agtttggcga taaaatcggt atccgccatc gatacttcat
    22921 attttttcgt atcagattca tcggaaactt ccacattgac gaaccaataa gctttggcat
    22981 gcttaggtcg ttttaaacca caccagggcg actaatcgcc ctggtgttca ctttttttta
    23041 ttttacttga actcattgac tgttttccct ttattttaaa cattataaag accgatgagt
    23101 gcttgccgcg tcttttgttt ttatcacggt tttttgtgca aaaaaacctg ccgatagttg
    23161 gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc tggcaattgg ttttctaaat
    23221 cagttcggac aacaagcaca tcgcaagctg cgtttctaat aacatattca gaaacagaac
    23281 caataaataa acgttctaca gcattcaatc ctgtggctcc taacataatc aaatctactt
    23341 gattatcttc tgggatttct ctggcaataa tttgttttgg tgagccatat tctacgacag
    23401 aggttacatt attcaagcca gctttcttcg cattgctttc ataatctgcc aatgtttgct
    23461 ttgccatttc agtagcttgt tctgcaagca ttccatcaaa ggatgaaacg gtttggaaag
    23521 aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt atttcggata gctacattga
    23581 ccgccttttt aaaagctaat tcagcttcat cagaaccatc tacggcaacc atgatttttt
    23641 tgtattgttg taacataagc attcactcct caagtcaatc gtattgtact cttttattgt
    23701 agaacacttt agggaaaaag agaattattt actgctttgg ttcagcaatt ttttttgcaa
    23761 atcggatact gaaggtggca gaaacaataa ttacgatcag taaaaagacc aaggcaataa
    23821 agcgttgatt gaaaaaagct gttaaaatac ccattacgcc taaaacagca tatgcagctc
    23881 cgtaaaattg taggaatcct tgatttttat catttttgtt gatcaataca aaaaagatat
    23941 cctgtttatt aaataaataa tagctaacga ataataatac taaagtggcg ataatcatta
    24001 aaatcctaat catgaacaaa tcctccaaaa taagcaacaa atagaaaaag caatttgcca
    24061 agagcaaatt gctttattct ttaaaagatg gtaatctccg ttaatgccgt tgtttgtcct
    24121 gtagtattga tcccgcgaat tcaagcaggt gggtcccatg gtcgtagctt cgaactacca
    24181 aatgataagg catgttacca gcagtgacac aagacgggtc ccaagatatc aataaaaatg
    24241 ttcggtcaac acacaaagag gacaattcga acatcacaga tttcccacct ctatagtagc
    24301 atatgaattt aaaaagagca atgagagagc tcgcagaaac agaaccgttt tcttgtctag
    24361 ttttttggag gatgcttttt ccactctttt atacggtaat actgttgacc cagagcctgt
    24421 tcatatttcc ctgtatcttt tggctgataa tactgagcac tcttcagttt atctggtaaa
    24481 tattgctgat tgacccaagc ctgatcaaaa tgatgaggat actgataacc cacgccacgg
    24541 ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat gatcaggaac atctccagct
    24601 ttgccctctc gaatatcagc aagtgctgca tctaatgcca tgtaggcaga attggatttt
    24661 ggcgacaagc aaagatcgac gacgacgtct gctagtggga tacgtgcctc aggcaatccc
    24721 aatttttcag cagctaatac agcgttcact gtacgagccg cagcagcagg attacctaaa
    24781 cctatatctt cataaccgat aaccatcaga cgccggcaaa tacttgccag atcacctgcc
    24841 tcaactaaac gggcgagata atgaagtgca gcatccacat cacttccacg aatcgatttt
    24901 tgaaaagccg aaataacgtc ataatgagca tctccatttt tgtcatgggt aagagctttt
    24961 ctttggacac attcttcaat gatcgacagt gtaagatgaa tccttccttc tttatctgaa
    25021 ggagtcgata gtgtagccag ttccagccca ttcaatgcac tccgcaaatc gccgttcgtt
    25081 gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga ttgcttgttg tccaaggccg
    25141 cgttctttat cccttaaagc atgttcgact gccaactgga tgtcttgttc tgttaatggt
    25201 ttgacttcaa agatctgtgt acggctgcgg atcgctggat tgatggtaat ataaggattc
    25261 tcagtagtcg ctccgatcaa gatgattcgg ccactttcta aatgaggaag cagaaaatcc
    25321 tgttttgttt tatctaatcg gtgtacttca tccaataaga ggatcactgt accactcatt
    25381 tttgcttctt ccgctacaac ttgtagatcc ttttttgaat ctgtagcggc gtttagcatg
    25441 cgaaatgcat aattagtaga gccggcgatc gcacttgcga tactcgtttt tccagtacca
    25501 ggaggtccat atagaatcat ggaagagagc atgcgagcat cgaccatgcg gcgtatgatt
    25561 tttccttccc cgactagatg ctgctgacca acgacttcat cgatcgttcg aggtctcatg
    25621 cgataagcca atggctgttg cataggattt tcctccttct tgtttttacg tcccttaatt
    25681 atatcatatt tagcaagatg cctagaaaga acagccttct gttgttttgt tttcatagct
    25741 tatccaacta atattgtgta tgataaagta ggtgagaaaa atgacggata aacaaaagat
    25801 agatgaattt ttttggaata aaacgacgcc agaagtggca cgggatttat tggggatgta
    25861 tttggagcat gacacaccag aaggaagatt agctggatat attgtagacg cggaagcata
    25921 cctaggtcca gaagacgagg ccgcccatag ctatggttta agaagaacac cgcgtgtgcg
    25981 ggcaatgtat gaaaaaccag gtacgatcta cctttacacg atgcatactc atcggatttt
    26041 gaacatcatt actcagccag aagggattcc tcaaggagta atgatacgtg caatcgaacc
    26101 cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga aaaactggtc cagatatcag
    26161 caacggtccg ggaaaattag tggaagcatt agcaattcct caagaacttt atggtcagtc
    26221 tatagcagat agttcgttac gcttagtttt tgagaaaaaa aagacaccaa aaaagatcaa
    26281 tgctttgcct agaatcggta tcccaaacaa aggtgtatgg acagaaaagc cgttgcgttt
    26341 tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa aaccaaatcg agaaagattg
    26401 gggttggagg aaagaaaatg aaaaagaagg atctattaac atatttagat gaaataattg
    26461 aaaaacaagt gacagactat gatgtagctt tagattggga tacaaaaaat catacgatcg
    26521 agatcgttgt tcgcttgttt gcagaaaata aagcacaatt tgagattgat gatgcagaag
    26581 ggatcgtttc gcaagaacca attatcgaat ttgaagacgg cgtacttctt tttaatcctc
    26641 agaaatctgt ttttgatgaa cgcaattatc tagcagtaat cccttatgaa ggaaaaaaag
    26701 ggttggcaaa atcagtagct gattctttag tggaatatct aaatgaagta ttagctcaag
    26761 ggcaaagcga tttgcttgat tttttggatg aagacgatga cgaagctgta ttcgagcttc
    26821 actgggataa tcagcaacta gcagaattag tagaagtaaa acagcaaaat gaagcagata
    26881 cttatttacc gtacccaagt tattaaggag tgacagatat gaaatggaat gaagtaaaag
    26941 tagaaactga aagtgaagca gtcgaagcag ttgctaatat tttgatggag gcaggggcga
    27001 gtggtgtcgc gattgaagat tctttagatg ttgaacattt tcagtcggat caatatggtg
    27061 agattttaga taaaaatgat tttacatcgc tgaaagaagg cgcactagtc atggcttatt
    27121 ttccggaaac gactttctta ccggaaatct tgccttttat caaagatcgt atcacacaat
    27181 tacctgagtt tggtctagct attggaaaaa ataaagtaac agttagtgaa gtagaggaaa
    27241 gcaactgggc aacagcctgg aagaaatact atcatccggt gcgtattacg cgaatgctga
    27301 cggttgcgcc aagctgggaa aactaccaga cagaagatcc tctagaaaaa attatcacac
    27361 tagatcctgg tatggcattt ggcacaggca ctcatcccac gacttccttg acattgacag
    27421 cactagaaac agtcttgcgt ggtggtgaaa cattgctaga tgtgggaact gggtcgggcg
    27481 tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt ctatgccttt gatttagacg
    27541 aagtagccgt tcgttcggcg aaagaaaata tggatatgaa tgaaatagcc aaagatgtcc
    27601 atgtatcagc taacgatctt ttgacaggaa tcgagattga aagtgatgta atcgttgcga
    27661 acattttagc agatatcatc ttattgatga tcccagatgc ttggcgttta ctgaagcaaa
    27721 caggcacgct gatcgtttca ggaatcattg aagagaagaa gcaaatggtt ctggatgcca
    27781 tgttagaaca agggtttatc gtggatcaaa ttttccagca aaaagactgg tatgcaatta
    27841 ttttgaaaaa accagaggtg gaatagatgc agcggtattt tttaaaagaa tcatatgaat
    27901 caaaagacta ttttgtttta gaaggggaaa actatcacca cattgtacgg gttatgagga
    27961 tggaacccga ggatgaagtt tttttggcat tcaatgatca aatagccatt gttgcagaaa
    28021 tcacggagat tactgaagag gctgtttatc tgaaagaaat taaaaaagaa gaaaatcaaa
    28081 aggaactgcc aagttcgatt accatagcga gtggctatcc taaaggggaa aagctggatt
    28141 ggatcgttca gaaatccact gaattaggag cgcaagcttt tcttggtttc ccggcatcag
    28201 cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg acaacaacgg cttgaaaaga
    28261 ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt gccatcagta gagttattgg
    28321 aaacgaaaca agatttattt gagcggctag atgattatga cgtggtcttg gttgcttatg
    28381 aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa aattcttagt gaaacaaaac
    28441 cagatagtcg aatcttagct gtctttggac cagaaggtgg attatcccgc gatgaagtcg
    28501 attattttgt agaacacaaa gggatacttt gtggattagg accaagaatc cttcgtacag
    28561 aaacagcacc tctttattta ttaagtgctg ctagctatca atgggaatta atgaatcctt
    28621 ctttcagcta acgttcttca ttaataaaag agtatcgaca gaaagaattg aaaaaatagt
    28681 caacaatttg tataatagaa acaattattt atacaatgga tacgaaaaat cgtttgaaaa
    28741 agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa ctgcacggat tttgggacaa
    28801 ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa aaaagaaagg gggatcgatt
    28861 cctgtgacaa aagaagaaat tttaacggga cccggtgtca taaagctcgt tagtcaatac
    28921 atgggtcccg aacatgtagc atttgttgag aaagcatgcg aatacgcgac tgctgcacat
    28981 gacggacagt ttagaaaatc aggcgaaccc tacattattc atcctatcca agtcgcaggt
    29041 atattagcag atttaaaaat ggatccccat acagtggcta caggcttctt acatgatgtt
    29101 gttgaagata cagaaatcac tttagaagat ctgagagaag aatttggcga tgacgttgct
    29161 atgttagtgg acggcgtaac caaattaggg aaaataaaat ataaatccca cgaagagcag
    29221 ctagcagaaa accaccgaaa gatgctgcta gcaatggctc aagatttacg agttatcatg
    29281 gtcaaattag ctgatagact acataacatg cgtacgttga agcacctgcg agaagataag
    29341 caaagaagga tcgctcagga aactttagaa atctatgcgc ctcttgcaca tcgtctaggg
    29401 atcagccgga tcaaatggga attagaagat acagcacttc gttatctaaa tccaaaacag
    29461 tattaccgta tcgtccactt gatgcagacg aagagagaag aacgtgaaaa atacgtaagt
    29521 ggtactgttg aagatattcg aatagcgaca gaagagctgg ggatttttgc agaaatctat
    29581 ggacggccaa aacacattta ttcaatctat cgtaaaatga aagatcagaa aaagcagttc
    29641 aacgaaattt atgacttgct agctattcga gtgatcgtag attcaatcaa ggattgttat
    29701 gctgtattag gagcaatcca cacaaaatgg aaaccaatgc ccggcagatt taaggattat
    29761 attgccatgc caaaagctaa tatgtaccaa tctttgcata ctaccgtgat cggtccggca
    29821 ggaaatccgg tagaaattca aatccgaaca caggaaatgc atgaaatcgc tgaattcggg
    29881 gttgctgcac actgggccta taaagaagga aaaaatgaaa aagtagaacc agatggtatg
    29941 acgaaacaat taagctggtt ccatgagata ctcgaacttc aagacgaaag ctatgatgct
    30001 tctgaattta tggaaggcgt aaaaggagat atctttagtg ataaagtcta cgtcttcaca
    30061 ccaaaaggag acgttactga gttaccaaaa ggatccggac cattggactt tgcatacagt
    30121 atccatacag atatcggtaa caaaaccact ggtgcaaaag taaatggcaa aatggtgcag
    30181 cttgattaca aattgaaaaa cggagatatc attgagatca tgacttctcc aaattcattt
    30241 ggcccaagtc gcgactggtt gaaattagtt gctactagca aagcaagaaa taagatcaaa
    30301 cgtttcttca aagcccaaga tcgagaagaa aatgtgatca aaggccacga atccgtggtc
    30361 aaatgtatta cagatctagg atttacgcct aaagatattt tgacgaagaa caaactgcaa
    30421 gaagcactcg atcgttttaa ttatcaaaca gaagatgatc tctatgcagc tgtagggtat
    30481 ggagaagtta gccccttgac gatggccaat cgtctgactg aaaaagaacg taaagaacaa
    30541 aaaatcgagc agcaaaagca agaagcagaa gaaatcatga atcagccgaa aaaagaacct
    30601 gacaaaatga aagtacgtca tgaaggtggc gttgtcattc aaggggtaga aaacttacta
    30661 attcgtatca gtcgctgctg taatccgatt cctggtgatg atatcgttgg ttatatcact
    30721 aaaggcagag ggatatccat tcatcgtcga gattgtccga atgttcagcc tgacaaacca
    30781 aatgtagcag aacgtttgat tgaagtcgaa tgggaagata catcgaatac acgaaaagag
    30841 tatgatgcag atttggaaat ttacggctat aatcgttcag gcttattgaa tgatgtactt
    30901 caaacagtca atgcgctaac gaaaaatctc aacagcgttg aagcacggac gaataaagat
    30961 aaaatggcga cgatccattt gacggttggt atccagaatt tatcccacct aaagagtatc
    31021 gtggataaaa tcaaagcagt acctgatgtc tacagtgtac gccggacgaa tggataggag
    31081 gacagatatg agagcagttg ttcaacgggt aagtaaagct gctgtgtcag tcgatcagca
    31141 agaaattgga aaaattggct acggcctact tgttttatta ggcattcatg aaaccgatac
    31201 gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa atgcgtattt ttgaagatga
    31261 acaaggaaaa atgaatatta gtgtagaaga tgtgggagga caaattttaa gtatctctca
    31321 attcacactg tttgcggata cgaaaaaagg aaatcgacca agctttgtgg aagccgcacg
    31381 accagaaaca gctattcctt tatacgaatc attcaatgaa ggaatcagaa gtcgcggcat
    31441 cacagtcgct accggacaat tcggagcaga tatgtcggtt tctctcgtca atgatggacc
    31501 tgtaacgatc attattgatt ctaaaaacaa ataaagtaat ctggttttca ctagtaaaaa
    31561 ctatgaaaca cgtcgcttaa gttagactga taaactctaa cttaagtggc ttttttgtct
    31621 gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt aagcttaaat tatacaagtt
    31681 attttttata ggaggttgct gaagatgaaa gaagtaccag tagtagatat caaaatcaca
    31741 gatttaaaaa aattgtatca aaaaggatac aacatgttgg aggagttacg ccatgaagcg
    31801 gacgctcccg tcgtcaaagc aaagattttc aataaagaag ctatcacgat ctacggatca
    31861 tcagcagcaa aagtatttta tgatccaagg aatttcaaac gaaaaggtgc tatgccaaaa
    31921 ttagtattga agacactttt tggtcaaggt ggagtacaga ctttggatgg agctgctcat
    31981 caccatcgga aaaatatttt tatggatcta atgacaccgg aaagaatgga agattatcat
    32041 cgtatcttag ataagaatct gacacaagca cttgaagcac agcatggtca atttgaacta
    32101 tttgatttaa gtaagatggt tttctttaca tctatttgcg agtgggcagg tatcaattta
    32161 tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat atcaaatctc tatgatcagc
    32221 ggaacgttta cttctccgat tgatcacata aaaggtgtcg aaaatcgcaa aaaatcagaa
    32281 aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc ctgtggctgg aaaagaaaat
    32341 gtggcattat atgcttttgc caatgccaca gatttagatg gtcagctttt acctctggaa
    32401 gtggcagctg ttgaattatt gaacatcatc cgtccaacgg ttgctctaac tgtgtgggcg
    32461 gcattgatgg gacatgcact tttcagtaga ccagatttgt atcagcaatt aaaaaatgac
    32521 ttttcgacgt tacaagatcc gtttattcaa gaaatgagac gctattatcc tttcttccca
    32581 atgctacctg cgatttcgct gaaagaagta gaagtagatg gttatcgtat accagaaggc
    32641 agttgggtta ttttagattt atatggaaca gaccatgatg aacgaacagt tgaagcgcca
    32701 gattccttta tgatcaaacg gtatgtaggg aaagcaaaag atatttccta taaagaagaa
    32761 tatgagatga ttgcacaagg cgggggaaat tttcgacaaa tgcatcgctg tgcaggagaa
    32821 tggatcactc ttcatagtct acgtgtgttt tccgatcagc tagtaaataa gtttgagttc
    32881 tctgtacctg aacaagattg gacgattcca ttcaatcagt ttccgactta tccgaatagc
    32941 cgagcgctac tttacaagaa ttagattagc ataaacttat cgaaaaaaag gaagatcaaa
    33001 cagtgctgat cttccttttt tcatattact ataaattgat aaggtcaatt gatcaaaatc
    33061 cacgaaatgc ttcatcaatg gtttgataat cttcattgga taaatgcaaa tctaaagctt
    33121 ggacattgtc agatacttgc tctggacgct tagctccagg tataactaca gacactcgtg
    33181 gattcttcat gtaccaagct aaaacaagtt gcgcaggagt ggcttggtat cttttagcaa
    33241 tggggcgaag tacatcgaca gcggttaaaa tttctctgaa acgttctcct tggaaatctg
    33301 gatttctttt tcgaggatct ccttcaccaa attgtttttc ctcaccaagt tcatattttc
    33361 ctgtcagcaa accggaagca agaggaaaat agggaacaaa actgattttg tttttttcaa
    33421 gataagggaa taattctttt tcagcctgcc gatggatcaa actgtattta tcttctacta
    33481 catcgacata tccatctgca ttcgcttctt tcaattgttc taacgtgaag tttgacacac
    33541 cgactgctcg gatttttcct gcttctttta attcgtgcaa tgtagcaact gattcatttt
    33601 ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc gatgtaatca gtttgcagac
    33661 gttttagtgc atcttccacc gattgtttga gaaactcagg agaattatca aatgttcgcc
    33721 ctttatttgg tacatgagca gcttttgtag cgatgacgac acgtgagcga tcatattctt
    33781 tttccttcag tacctcgcca atcagttctt cggaacggcc gtttccgtaa gcataagcgg
    33841 tatcgatcaa attgatcccg ctattcaaag ctgtacgaac tacttgtttt cctgtctcat
    33901 cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt tgctcctaat ccaagctgtt
    33961 ctgcgtagac ttgtgaatgt ccgattctta tttctgccat agctgattcc tcctttttgt
    34021 ctagtctaaa acaaaatacc aaaaagctga actaaaacgt ttttgtgagg ggaaatagtc
    34081 agatatctct tgactttgag actggttttt agtaggttat aagtaatatc gaatgtcaat
    34141 gaaagagcga gtaagttttt gaaactttac aagagaggat catcgaggct gaaaatgatc
    34201 taaagtttca ttagcctaaa gacactctgg agatggacga gtgaaaagcc gtcccgcgta
    34261 cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat taggtggtac cgtgtatgaa
    34321 tttcattcac ccttgttcat gatgaacaag ggtgattttt ttatttacat agctaagaaa
    34381 gggagagaaa actatgagtt tccaaagacc aaaaggaaca aatgatattt tgccaggcga
    34441 atcagaaaaa tggcagtttg tcgaagaaac agcacgttta ttattcagag attatcagta
    34501 taatgaaatg cgtacaccga tttttgaaca ctatgaagtg atatcccgaa gtgtagggga
    34561 tacaacggat atcgtttcaa aagagatgta tgatttttat gacaaagggg aacgccatgt
    34621 gacgcttcga ccagaaggta cagcaccaat cgttcgttct tttgttgagc ataaattgtt
    34681 cggcccagag tatgcgaaac cgttcaaaac tttttatatg ggaccaatgt ttcgctacga
    34741 acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc ggagtagaag catttggatc
    34801 agaaaaccct gcaactgatg tggagagcat ggtgatggca cttgatttct tcaaacagtt
    34861 ggggatcacg caaatccggc tagtcatcaa ttcattaggt gataaagaaa cgcgtcaagc
    34921 ctatcgtcaa gcattgatcg actatctttt accttttgaa tcagagctga gtgaagactc
    34981 taaacgccgc cttcatgaaa atccattacg cgtattggac agtaaagaca aacgagatca
    35041 aaaatttgtg gcagaagctc catctatctt agattatcta agcgagcctg ctcaaaaaca
    35101 ttttgatacc gttgtttcca tgctggatgc attggctgtt ccttatgaaa tcgacagtaa
    35161 tatggttcgc ggactagatt attacacaca tacgattttt gaaatcatga gtgacgcacc
    35221 aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt tatgacaatc tagtggaaga
    35281 actaggtggt ccttcaacac ctggcttcgg atttgcaatg ggtatcgagc gattactctt
    35341 gactatggag gcagaggaag tagttatccc tgcatttaat gagttggatg cttacgtggt
    35401 cgcactcgga gacgaaacaa atatcgaagc attgaaagtg gtccaagcga ttcgaaactt
    35461 tggtttttca gctgaccgcg acttcatgaa ccgtaaagca aaagcgcaat ttaagacagc
    35521 agataaagcg aatgccaaat tagtattggt gatcggtgaa gatgagcttg ctagtcaaac
    35581 gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt tttccattag aagagatata
    35641 tgaacatttt gatgaagtct atgatgaaat gactttattc gagtaggagg aaaaaaataa
    35701 atggcacaaa gaacgatcta ttgcggatta gtttccgaac aacaattaga acaaacagtt
    35761 acattaaaag gatgggtaca aaaaagacga gaccttgggg gagtaatctt tatcgaccta
    35821 cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg aaatcaacaa agaagcatgg
    35881 gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag tgactgggga agttagaaga
    35941 cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg aattcgaagt gattgcaagt
    36001 gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc aaattgaaga tgatcaagca
    36061 atcagtgacg aaatacgttt gaaatatcgt tatttggatc tgcgtcgtcc aaaaatgact
    36121 aaaaacatca aattaagaaa tgcgacaaca aaagcgattc gtcattattt agatgataat
    36181 gactttctcg atatcgaaac accttaccta gggaaatcta caccagaagg cgcaagagac
    36241 tacctagttc cttcacgtgt ccatgctgga catttctatg cgttgccgca atctcctcaa
    36301 ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt attatcaaat cgttcgttgt
    36361 ttccgcgatg aagatttacg tggagaccgt cagcctgaat ttacgcaagt agatattgaa
    36421 acaacgttct taacagcaga agaaatccaa acttacacag agggattgat tgcgaaggta
    36481 atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc ctcgtatgac ctatgatgaa
    36541 gcaatggctc gctacggcag cgacaaaccg gatacacgtt ttgatatgga attgatcgat
    36601 ctaagcgata cagtcaaaga agtagaattc aaagtcttcc aaatggctct tgaaaacggc
    36661 ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc gctactcacg aaaagacatg
    36721 gatcagttag gtcaatatgt aggacaattc ggagctaagg ggcttgcatg gctgaaagta
    36781 gaagaagacg gattgaaagg tccaattgct aaattcatgg gagaagcaac agaagcaatc
    36841 attaaagcaa cagatgcaaa accaggtgac ttgctgatgt ttggcgcaga taaaagtgaa
    36901 atcgtcgctg ctgcattagg tgctatccgg acacgtttag gaaaagaatt aggactaatt
    36961 gatgaatcga aattcaattt cttatgggta actgattggc cacaatttga attttcagaa
    37021 gaagaaggtc gatatgtctc tgctcaccat ccattcacga tgccaaaaga agaagatatc
    37081 ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag cttatgatat cgtcttgaac
    37141 ggttatgaac taggcggagg ttctatccgt attcatactc gtgagcttca agaaaaagta
    37201 ctagaaactc taggctttac aaaagaacaa atggaagaac aatttggttt cttgttaaca
    37261 gctttagatt acggattccc tccacatggc ggtattgcat taggattgga ccgttttgca
    37321 atgttattag ccggagaaga taatattcgt gaagtcattg cctttcctaa aaacggaaaa
    37381 gcagcagatg tgatgagtga tgcaccaagt atggtttcgc ctttacaatt gttcgaattg
    37441 aatattgatg taacgaatat agaagaatag ccgataaaaa ggtaaaaagg atttgtcgaa
    37501 tacgcttctt ttgacaacct tgatttaatt gaaaaacact ttataatgaa gccataacat
    37561 ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt gggcttatca tgattacacg
    37621 accaagcttt cggtatctat cgtttatgcg ttgatcgcat cagtcgcatt gaatttcttt
    37681 tatcagccag gacatattta ttcaagtggt attactggtc tagctcagat tttgacgact
    37741 ttgtcaaaat cactgatagg attcgaagta ccggtatcaa caactttgta tttactgaat
    37801 atacctttgt ttgtattggc gtggttaaaa atcgggaaga agtttacaat tttcactttt
    37861 atcacagtca ctttgacctc cctttgtatc catattttac cggaaacagt cctatctacc
    37921 gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg gactaggtat tgggctagcg
    37981 ttgagaaacg gcctatcatc gggcggtcta gatatcgtga gtatcacgat tcgtaaaaaa
    38041 acaggaaagt cgattggttc tatttcgatc tacttcaatg cattgatcgt ttttgttgcc
    38101 ggaattctat ttggctggca atatatgttt tacagtacgt tgtctatttt cgtcagtgga
    38161 aaagtaactg atgtcgttta tactaaacaa aagaagatgc aggtaatgat cgtaacgaaa
    38221 catccagaaa aagtagtaaa tgaaatccaa aactgtatgc gtagagggat cacgatcatc
    38281 aatgaagcag aaggtgctta taagcatgat aagcagacag tattgatgac gatcgttaca
    38341 cgatacgaac tgcctctact tagagaagca atgaaagctt ctgatccaca agcttttgta
    38401 agtattgcag aaaacgtcca gatacttggt cgtttctatg aggatggcat ttagatcgag
    38461 tttgacaaaa attcatgaaa tactgctgta gacagacgtt cgtttgtctg cagttttttt
    38521 ctaccatagt agaatcagca aagaaaaact gcttttttat ttgaaatttt cttaaagttg
    38581 aaaaaaagca tgtttatttt tttaaattta tgggatgata gaaaaaaata gtagagaaag
    38641 gacacgattc tacttgctat tttcacttaa tacccgtata ttacgaatga aaaaagttta
    38701 tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta aaaaacagcc gctacatcac
    38761 tgggtttgat gggctccgtt cattagctgt ggtgggtgtt atcttctatc accttctgcc
    38821 aactagtatg aaaggcggct atttgggcgt tccgattttt ttcgtcgtat ctggttattt
    38881 gatcacggat ctgctgcggc aggaatggga acaaaatgga aaaatcaata tttggcaatt
    38941 ttatgtcaga agaatgaaga gactctatcc ggcacttgtt tttatgcttg tgacagcttc
    39001 ggcttatatc actttgtttc agcgagggct gttaaacaat cttcgaggag ttgtggtcag
    39061 cagcttactg tatgtcaaca actggtggca aatcaataac ggtttatctt atttcgatcg
    39121 atttgctaat gagtcaccgt ttacgcatat ctggtcttta gcagtagaag gtcaaaacta
    39181 tttggtttgg ccgatcttgt ttgtattgtt gatggtattt gttcgtaaaa gaaaatggat
    39241 cttttatact gtgttaggta catccttcct ctccgccatc ttgatgatga tcttgtatac
    39301 accaggaggc gatccaaccc gtgtttatta cggtaccgac actcgtctgt tttctatatg
    39361 gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt ttaaagaaaa acatcccgaa
    39421 acaagcgaaa aatattctga atatcgctgg aggaatctcg cttttggcac tgattctttg
    39481 cttcttcttt ttagatgatc attacaattt catctattac ggaggaatgc tcctagtgag
    39541 tctgttatgc gtagtgctag ttgcagtgac agcacacccc ggagcaagtt tgaatcgatg
    39601 gctgacaaat ccagtattta cttggattgg caaacgaagc tatggcattt atctgtatca
    39661 gtttccagtt atgatttttt atgaagcaaa ggtgactgat attgccgatc atgttttgtt
    39721 gcatacttta gtggaaatca cattgattct aatcatcagt gaactttctt atcgatatgt
    39781 ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc caagtgatga aaggatggtt
    39841 cagcaaaccg atcatcagta agagcaaacc atgggttgtt ccaggcacat tacttgtagc
    39901 aattgcactc gttggtttcg ttacggcacc gaaaaacgct gtaacagccg atcaaaaaca
    39961 actgcaggca aaaatcgctg aaagtaaaaa attagcagaa gaaaccagaa acaattcaga
    40021 aaacaccact agttcggttg accaagcgat ccttgataag tacgagttgt ccaaggcaca
    40081 agggaataag gcacaaaaat tagaactaac ggcatttggt gattcagtta tgttggatgc
    40141 tgcaacggat ctacaagaac tttatccaaa agtagtggta gatggagatg tcggacgaca
    40201 attatatgcc agtgtaccgt acattgaaaa attaaaggaa caagatttgt tgaaagacac
    40261 tgttctgatc ggactaggaa cgaatggctc attctcggaa gctcagtttg atagtgtgat
    40321 ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc cgagtaccga cgaagcgctg
    40381 gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa aaatacgaca atatgacgct
    40441 gattgattgg tacagctaca gtaatgacca tagtgactgg ttttatgatg atcaagtcca
    40501 tccaaatcct gaagggatga cacattacat tcacttagtc agcgaagcct tgctaggagg
    40561 aagttcaagt acgaacagca gtgagacaaa cgtgacagaa tgatagctac aaaaaacttc
    40621 aggcaaaaac atttgttttt gcctgaagtt tttttatatt taccgtgttt ttaacattca
    40681 tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa taacgttctt tttgttttcg
    40741 ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg cttcttgaag aaaatacttc
    40801 tgcatggatc atcttaacag gtcttctttt ttgaagacga gtatatttag caccagtacc
    40861 attgttatgt tcctctaatc gtctagaaag atcggttgta tatccaccat aaaatgtctg
    40921 atctttacag aataatacgt aaaaataatg ttcatttgcc atagagcatc tcacgaatct
    40981 ctgcagtgta ttctccatcc atattgtaag tgatcaatgg tggagcgact ttgaatccgt
    41041 ctaatttgcc ttctttgatt ccttcaacta acaaaatatt tgcctctttt ccaggttttg
    41101 ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc ttccatgacc tgaatgattt
    41161 ctaagaaccg atcaggacga tggaccatag taaagcgtcc atttgttttt agtagcttac
    41221 ttgaaatatc gatcacttct tctaacgtcg tatgaatctc atgacgggcg attgccaggt
    41281 gtttattagg gttcgtttta tttgttggca gccctttgaa ataaggtgga ttacagacga
    41341 ctaagtcaca agaattatgt cgaacgacag ataagctgtc tttcagatcg atggtgtgga
    41401 cagtcatttg ttcatttaaa tggttaagcg cgatactacg tcttgccatg tctgctagac
    41461 gaggttgaag ttcgatagcg tcgatagccg cctgggttcg tttacttaaa aaaagtccaa
    41521 ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt tttaggtaca cgggaaaagt
    41581 gagcaagcag cacagcatct aaagaaaaag aaaacacttt ggaactttgg ataatcttga
    41641 tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg aagcatggat tccctccaaa
    41701 atgaaaaaaa tagtcgtctg tattatacta tttttattaa aaagaaccaa ggtggcttgt
    41761 caaacctcta ttttttatgc atactatgac cataagaagg gaaaggaaga gactatgttt
    41821 tatcgattta tgcgcggggt agttcgagta ctattagcct tagttaatgg aaatgcccgc
    41881 tatgagaata aagaagtttt accgcaagat gagaattaca tactagttgc tccccatcgt
    41941 acttggtggg acccattata tctggcggta gctgcagcac ccaaggaatt cagctttatg
    42001 gcaaaagaag aactgttcaa aaatccagtt ctgcgattta tattaactcg atccaatgct
    42061 tttccagtta aaagagaaaa tccaggacca agcgtcatta aaacacctgt aaagattttg
    42121 aaatcgacaa atttgagttt gatcatgttt cccagtggga caagacatgc tacagaactt
    42181 aaaggcggaa tggcattgat ttccagaatg tctaaagcga aaatcgtgcc agctgtatat
    42241 caaggtccgt tgacacttgg ggatctgttc aagcgtcaga gagtgacagt gcgtttcggc
    42301 gaaccaatcg acttatcaga tatcaagaaa acggataaag aaggtatggc ggagatcgaa
    42361 cgacgaacac aagcagcttt tgacaaattg gacaaagaag tgaaccctga tttcaaatat
    42421 gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc ggtcttttga atctactgtc
    42481 ctgttcagtt cagacttttt caatgaaaac gagggagaga cgtcaagtct gccctctttt
    42541 tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa tggatcaaag tgttataata
    42601 attagaagga cattttttga ggtgattgaa tgcgtttttt acatacagcc gattggcata
    42661 tcggaaaaaa actacaaggt tatgacttga ttgaagacca gcgtcatgta ctatcttcta
    42721 tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt gattgccgga gacttatatg
    42781 ataggagtgt cccagctgtt gatgccgtag aattatacaa tgaattgatg gtcgattgga
    42841 atttaaagga aaagatcccg atttttgcta tatcaggaaa tcacgatagc agtacgagac
    42901 tttcagcggg tacgccatgg ttcagttatt cgaactattt tttgcgaaca cagctagcag
    42961 aagcatttga accagtcgag tttaaaaacg tacaattttt ctttcttcct tactttgaac
    43021 caattgcagc gagattatat tttgaagatg acaatatccg aacgatcaag caagcggtag
    43081 ccaaggtgat agataaaatg caggagctat ttgattcaga aaaaaaacaa gtattgatta
    43141 gccatttttt tgtaatggga agtgtaaaat ctgattcgga aacgaaaatc gaagtaggcg
    43201 ggttggattc gatccctggt gaactactta caccgtttga ttatgtagca ctaggacatt
    43261 tgcataatca agctgctttg agacaggata atgctcgcta tagcggttcc ccattgaaat
    43321 tctctttatc tgagatcaac caaaaaaaag gcgtatggat cgttgacctg acaacaggcc
    43381 tggagttgaa ttttagggag atcgaacccc tgcatgatat tgaagaaata acagcgagtt
    43441 tcaaagaatt gctggatcct gccttttatc agtccgtcaa tcgggagaat tacatctata
    43501 tctatctcac tgatagaacg atcatcccga atatgatgaa ccagcttcgg caaatatatc
    43561 ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga acaaacaaag cgcaaacgaa
    43621 aagtactaga aatgaaagat cctcaaaaat tagcagaagc attttttagt gaaatgacgg
    43681 aagagcagct aactgcaaac caagaaaaat ggctcggaga aacgttgcaa gaaatcatgg
    43741 aaatggaatg atcaagaatg aaaccgaaaa aattacaact taaaaatttt ggtcctttta
    43801 tcaatgagac cgtagatttt tcacgtttga cagaagcacc gctttttttg atcagcggga
    43861 agacaggagc tggcaaaacg acgatttttg atgggatcac cttcgcactt tttggtgaaa
    43921 cttccggaag acttcgctct ggaaaagaga tgcgttcttt gtttgctaca ccagacgaag
    43981 aaacaagcgt gactttttct tttgaacatc agcagatgag ctatgaaatc gaacgaaaac
    44041 cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa aaaacaggca gccaaagtaa
    44101 cgttgaccat ttttgatggg aaaggaaaag aaataaaaca aatcacaaaa cgtacagaag
    44161 cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa acagttttct caaatcgttt
    44221 tactacccca aggagaattc cgtaattttt tggtttcatc aagcagtgat aaagagactg
    44281 ttttacgtca tttattcggt actcaatttt tccaacagtt caatgagcga ttaaaagaaa
    44341 aagcaaaaca acagcaacaa aaattggatc atttagagca agagctgcat cttctgcaaa
    44401 aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg gtttgaagcc gttttagccc
    44461 aatggacaaa ccatcaggca atactcgaaa aacaaatcac ggaagaaaaa gaagctctaa
    44521 cggaacttca ggaaaaacaa aagcaactag aaaattccta ctatcgtttt gaaagcttga
    44581 aaaaaagtta tgaagaaaaa acgatattaa taaacaagca aaaggaatta gctgctcaaa
    44641 aagacgaaat agaggaaaag aaacgatgga ttgggtatta tgaatttacg caacgattag
    44701 tcgaaccaat ccagcgccta caagaaataa aagttgaaaa aatagaactg tcacaaaaaa
    44761 gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa ttatgaagag tggcaaaaaa
    44821 atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga agctgctcaa aaactgcaaa
    44881 acaaacagat gatggtgcca attgtcgaat ccttacgtag taaaaaacaa gacgcagaac
    44941 aattaacaat ttcattggat aaagaagaat tgaatgccga gaagctgtat caaaatctcg
    45001 ctatctatca ggaaagaact cgaattcttc aagaaaattt actggatcag gaaaaactgc
    45061 aagaagatcg tcttgctttt ggacagttaa aatatctaga tgaaaagcag caagaaatag
    45121 aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat aagagaagaa ctcaaaaaag
    45181 caactgaaga aataacaaaa aatagtcagc tattgaaaga acagacagaa caagcagaac
    45241 agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct tcagcttttt ttgcgtccag
    45301 gggagccatg tcttgtttgt ggatcaacgg aacaccccat acaacaatta aaacacgaac
    45361 agccaaataa ggaagatatc ttaaaagtag aacaacaact ggcagaagct gagtctgctg
    45421 tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca tgaaaataat cttcaacaac
    45481 aattatcaga tttagaacaa aaaatcatgg caacgaatat acaattggct gaacaagaag
    45541 aacacttgca acaggctttg aaaaaggcat ttcctgagat aacagaacaa aaaacaaaaa
    45601 caactcttgt agtaatcgaa caatctttag atagacgaaa aagcaagatg gccaatgcaa
    45661 gaatagagct ggaagaaata agacaacaag cagaaaagct cgaacaacaa ttagctgtct
    45721 acaaacagca gcagacagaa aaaaataatc agctccagca actgcaagga gaaatcaaaa
    45781 gtttagaaca acaattgcaa gatacggata gtaactgttt agaagaggag atacgacgac
    45841 ttgaaaaaca gttagaagaa gactcgaatc aactagctgt tgagcagaaa gcaggagtgc
    45901 aattgttgca agatcttcat acgcttcgga cacagcttga tcttcaacat gaacaaatag
    45961 aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat agctaaaaag ttagaaagcc
    46021 agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc acaacagcaa gcacaatata
    46081 aagaaaacca acgtacagtt acttcttatc atgaagagca attagtgaca gctgaccggc
    46141 tgcgtcaatt agaaaatatc cagctaactg agacattccc agatacagaa gagatcagcc
    46201 aacagttaga agaaataaga cgtatgatcg aaataaagca agaaaagata tacggtttac
    46261 aagaacaaaa aattagtaat caaaaaatct acgatgaatg tctttcgatt tatcacacaa
    46321 gccagacgaa attagatgag cttacgcaat tacagcagct ttcgcaaaca ttcaacggag
    46381 aaaatcctaa gaagactagt ttggaacggt atgtgcttca ggtttatctt caagaagtgt
    46441 tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa tcgttatcaa tttgagctag
    46501 cggataccat tggcagttat cgagggaaaa ccggattaga aatcaatatc tatgatgatc
    46561 aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg tgagagtttt attgcagcac
    46621 tttctttagc attagctctt gccgatgtga tccagacaca agctggtggt gtagcaatcg
    46681 atgcattgtt tattgatgaa ggatttgggt cattagatga agaagctttg gaaatggcaa
    46741 tggaagcttt agaaacgatc gaaagtgaag gaagaatgat cggcatcatt agtcatgtaa
    46801 gagaattgaa agaacgagta ttacaacaaa taagaattga tacagaaggt agcggacaaa
    46861 gcaaaatacg ctatcaactt ggataaaaag ggagattggt aactatgaaa tggagtattc
    46921 cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga aggccgagtg ttatcggttg
    46981 tccctgacca agaagaaaac gtgtggcatg cagaagtctt gggcagtgaa ttgtatatgg
    47041 ttgatttgga tggtacagca aaagagatag attactgcca atgtccctat tgggaggaac
    47101 ataaatattg taagcataca gttgctgtgg aactttattt acggtcgaaa aatctatctc
    47161 gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa agcaacaagt gagggagaaa
    47221 tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa tcctcaagcg gtgcaacctt
    47281 tgattattga ataccaagta gaaacgattg agactaatca gtatcaccca gagctttcta
    47341 ttttggcact ttacttgcgt atcggttcat tggcatcacc gaaaaaaaca tatatcgtaa
    47401 aaaacatcta tgatttttta caagcttaca cagaaaaaga aacttacact gttaataaac
    47461 agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga agatcaaaaa atactcacgc
    47521 atcttgcagg aagtgctcag acgcatcaat tattaggtac gaacggctta caagtcaaag
    47581 gaaaactaga taaaagatat ctgcttctcc cagtagaaca agcccgcttc ctgttagagc
    47641 agatgaatca gactacacgt ttgcatctgc agataaatga acaaaacgat caaggaatac
    47701 aattttccga tcaaaacaaa cctttatcat tcaaagtgga aaaatttgga gaagattatt
    47761 tgctgcaagc attgaatgat tttgattttt tctttatgca ttatcagtgg ggagttatcc
    47821 aagggacatt ttattctctg acgaaatatc aacaaacggt ttatcaaact tggaaacaat
    47881 tgattcgccg attggagaaa ccagaagtag tgttcaagaa aaaagaatta ccgtctttgt
    47941 ttaaagagat tatccctctg ctgtcagaga tcggcgacgt agctattgcc cctgcagtag
    48001 aagaggaagt agcagatatc cccgtcgaat ttattttctt tttccgaaaa gcaaaaggaa
    48061 aaatccaagc tcgagtcgat ttcgtctatg gcgaagtcat ctattcgact gacccgaagc
    48121 atgaggtctc gacagaacag gcttttcagg tgttacgtga cacagtagaa gagaaacgag
    48181 tacttgatct attcagaatg tatcgctacc agaaaaatga aactggttat gaacgtccat
    48241 tgccaagcgg ggaagaacta tatgcctttt tccgcacaga actatctgtc ttccgtcagt
    48301 ttggtgaagt cagacttgga agaaaattgc gagagttgta tttagatgcg cataaacatc
    48361 aaccgaaaat cgaagtaacc gagaccggtt catggctcga tattcgattc gatgtgacag
    48421 ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt gctgagaaat gatgcttttt
    48481 atacattaga aaatggtcag gttctttctt ttgattcaga agaatttcaa caaacaagcc
    48541 aagtgttgca acaattacgg gaatcgatac gtacagaaga aggaacgatc catgtaccta
    48601 aaaatcaagg attgatcatt caaaatcaat tggaaaaaag caatgctact tttagtgaat
    48661 cgttccaaac gatggtacaa gatctcattc atccagaaag ataccaggca cagcttccca
    48721 aaggattgaa tgcaacgatg agagattatc aaaagcaagg ttttcgatgg ttgaagatgt
    48781 taggtcatta tcagtttggc ggtattttag ccgatgaaat gggacttggg aaaacactac
    48841 agacaattgc ctttttactt tcggaaaaag aagaacggaa aagcttctct gctttgatcg
    48901 tagcgcctgc gagcttaatt tacaactggc aggcagaggt gagaaaattc gccccttctt
    48961 taagtatcca agtaatcaat gggaataaaa aagaacgtga agaattactg gctaaagaca
    49021 cagatatccg agtgacttct tatgccagct taagacagga tctagctaat tatcagtcgc
    49081 aaaaaattga ttatttgatt cttgatgagg cacaaatggt caaaaatagc agtacgaaaa
    49141 ctgcacaagc attgagagaa ttagctgtac ctcagcggtt tgcactgagt gggacaccaa
    49201 tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac gattatgcca ggatttttcc
    49261 cgactaaaac aaaattcagg gaacttgccg cagaagaaat tgcgcaaatg attcgaccgt
    49321 ttattttacg gcgagataaa caaactgtgt tgaaagactt gccggaaaaa acagagatga
    49381 atctatattc tgcacttaca gaagaacaaa aaactgttta tttagcttac ttgcgtcaaa
    49441 tgcgtgaaga aatcacatca atggattctg aagcattcaa gaaaaaccgg atcgggatac
    49501 ttgctggtct gacaagactg cgacaaattt gctgcgatcc tcgtctgttt attgaagatt
    49561 accaaggcgg ttccggcaag ctcgaacaag taaaagatct actggtagct gccaaagaga
    49621 acaaacgaag agttttgctg ttttctcaat ttacagggat gctgactatc ttgcaagaag
    49681 agttagccga gctagggatc tcgacatttt atttaagagg cagtacgaaa ccacaagatc
    49741 ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga tgtttttctg atttccttaa
    49801 aggctggggg aactggattg aatctcacgg gagcagatac ggtcatcttg tatgaccttt
    49861 ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc acatcggatc ggacaaaaaa
    49921 atgtggtaga agtgtggcgt atgatctctg aaggaacgat tgaggaacgc atggattcac
    49981 tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca aggtaatgaa gaacagttga
    50041 cgaaactgac tgaagaagac atccgcatga ttttaagtgt aggagaaatc gaggagtaag
    50101 agactcgaaa aagcgttcag taatgggtaa gaaagccttt ctaaagaagc gattgtttat
    50161 ttgatttaaa aaatagcaag gaggctggga ttccatttta tcccagcttc cttgctatca
    50221 tttttttatt tctattttta aaggttatac aaagattgtc ttcattgtct ctaacagctg
    50281 atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt tcaattttgc gttctcgatg
    50341 gttgaaccaa agcgcttgcc agttagcact ttttgcacct agaacatcat tgtcgtaatt
    50401 atcgccaacg tataaggtct cttctggaag catatgaaat tctttctcag ctagctgaaa
    50461 aatctctttt tctggttttt ggaaacctgt tgcttgagaa atgagcatat tgcgggaagg
    50521 aatccaattg ttcaattgaa gttgcttcag tttttttgtc tgatggtcag tcggcccatt
    50581 tgtgataatt cctaatggga cattcttttc cttcaagaaa tcgagggttt ttttgacctc
    50641 ctcatgcaag cagatattat caagttcttc ctcgtaaatt ttttgaaata agaggccatc
    50701 ttcttccgta atatgagggt agtctaaatc ttttagtgat tggctgatcc gatgtgctcg
    50761 catatattct agtgtccaat ctcctgccat tacttttggg aagttttcat cactatgatg
    50821 gcggaaccgg atatatagtg gatgcatatc tgcatctgaa acaagcggaa cgactctttt
    50881 gaccgcgttt cgaaatggct gctgctgatc atacatcgta tcatcaacat caaacacaac
    50941 tgatttaatc aaaattttac acgcctttcg gttttcattg attttttcac aaatccttga
    51001 ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat aaaggttttt cttactatat
    51061 ttctatttcc ttgacagaat aaggttttta tatttcagtt tttttcacta aaaatcgtga
    51121 aacacgtcaa taagtttgat gaacaaatta atcattatgg tagaagtcga ttgatttatt
    51181 ttaatgcaat ctctgtggaa ttttcgaaag atttattttt ttaatacagt ctcaatataa
    51241 ctattcaaac ataaaataac gttatttgat ttatttgttt atagtaaatt ttatttagta
    51301 atcattgctt taaaatacta cgcttatata acagagaaaa taagcgttat aataaagaac
    51361 agtattattt aaaatgacag aaaacattac tattaaagaa ataaaaaaca taaaaaatct
    51421 taagaaatcg gtttcattta gcttttgaga taaaataata gtacagtttt atacgctgtt
    51481 tcatatgttt agaaaatttg aattagattt gaaaactcta atttttaaat gataaaaaaa
    51541 gcgagaatgc tggttttact gtatattaac cttagataac tttcattttt ttaaaaaaat
    51601 tatgaaaaaa aggtagctat ttaaaagttg attatgtata atagaaacag atgggagatt
    51661 attatgatct tctgttacaa aaaagtgatt cttatcacga aaaggagtgg tgcacgttgt
    51721 taacattata tacttcccca agttgtactt cctgcagaaa ggctcgtgcg tggttgcaag
    51781 aacatcagat tccatttgtt gaacgtaata ttttttcaga accattgaac agttctgaat
    51841 taaaagcgat tttacaaatg acagaagacg gaacagaaga aatcatctcg acacgttcca
    51901 aagtattcca aaaactgaac atggatttag atgatctgcc gttacaagaa ttattggaac
    51961 ttgtgcaaaa caatcctgga ttgcttcgcc gtccaatcat gattgatgat aaacgtctgc
    52021 aagttggttt taatgaagat gaaattcgtc ggttcctacc gcgcgatgta cgacaattag
    52081 aattacgtca agcacaattg atggctggat tatagaagga taatacgaaa cttggaaaag
    52141 actattacaa agatagtttt tccaagtttt tttgttttta caaaaagtat tcttgattag
    52201 atgtataaaa aggtagtaga agatgatgat tgcacgaaaa atagagaggg aaaattagct
    52261 gaaaagtcgg ctatatagta ttcgtctgcc aaaaatgtta tagttaaata agatagcttg
    52321 aaaggttgaa aaatccgctg gttttattaa attcgcttaa cagcgagatt ttttttcttt
    52381 acatttaagc tgatttcgct acaatgaatc tatattaaac attgtggcaa agtgaggtgt
    52441 agcaaaatgg aaatggaaca tattaatgaa aatacgatcc gtgtactaat tggtcatgaa
    52501 gatttagagg aacggggcgt ttcatttttg gatttacttg gcaatcacaa agaaatcgaa
    52561 aatttctttt atagtatttt ggaagaagtt gatatcgaag aggagttccg aggaagcgaa
    52621 gctgtcactt tccaagtttt gccaaaagga gacggattag aactgtttat cagtaaaaat
    52681 cttccggatg aagaaatttc tcaatcagaa gattctactg ttgattcaga agatgtgagt
    52741 gactttcttc gtcagcagat tattggcagc gatccggagg aagaattatc tggaagcgcc
    52801 ctagaagaac aggaaagaca agcaactttt gcttttgaag attttgaaca agtgatccaa
    52861 cttgcaacag atgtcgaact agagtctgct tggactgatt tgtatttatt cgaagagcgc
    52921 tattacctag tcgttcactt ctggatggaa aatctcaacc aagcggatgt agagaatcag
    52981 attgctcgaa ttttggagtt tgctgaaaag agcgatcgta caccagaaac attgaatgaa
    53041 tatggacaat gtctgatggc gcgtaatgct atcgagcgaa cgaaatttta ttttgtataa
    53101 atcagcatta tagtaagaga ctgtgacaaa aattgtgtcg cagtcttttt ttcgtataaa
    53161 tgtgttcaaa agcttgcatc tgcggtaaca agcccaacca aacgaaaaat attgggaact
    53221 atttttgttt agctgttctt attacttgat gcagaatagc tttttcacgc cctctttttt
    53281 cgtgtaaata aattcttaga cgtaaataag ttcagaggga gaaaaatgct gcttgcaatg
    53341 aatgaatata ataagtgctg ttttgctaaa catgcagaaa aaggaaagaa atattattgt
    53401 cgtggctgtc gaaaaagagt gattttgaaa aagggaaaga aaaaatgtgc tcattttgcc
    53461 catcaaaaat cagataactg ttcggtcttt agtgaaagag aatcaaaaga gcacttacag
    53521 ttaaaggaat gcttcatgga ttggctggga cagtcagtag aaccagtatt tttggaagcc
    53581 tatttgccga ggttgcggca aaggccggat attttgttgg cgaatctagc aatagaaatc
    53641 caatgttcta gactgtctca ccagagattt attgaaagaa cccaaaatta tttgaataac
    53701 agttaccaag tatggtggat acttggtaat tcttttcttg gacaatcgca attctcattg
    53761 atagaaaaaa gttgctgcta ctataataga aaaagaggag tgcattgctg gaaagctgat
    53821 ctcaagaaac aaaagcttta tttgtatcat catattacag agactgtatc agggcatatt
    53881 tccttttgca gtagctgctg gactttttct agtagggacc ttaaagaaat attcactagt
    53941 aacgaaatta aaatgaacca aatgaaaaaa atagaaaaag tgagtgaaga tgggaagaaa
    54001 tggctgacac gccaacttat tcacaagcaa aagaatacag tatccataca agaacaatgc
    54061 tacttgcgtc ataaacatct tttgcatcta tcatcgtgga tctatcaaaa aagtcggttt
    54121 ttcttttatt tacaagaaca ggtttttctt tatcgaatgt tgtacgaaga agccttggaa
    54181 aaccagaaag ttcctgattt caactcatgg ctttgccaaa taaaagaaca taaaagggaa
    54241 tggctttttc ctatgattga tgaagagatg gtctatcagc agttttttaa cgaatgcata
    54301 cacttgtctt ctttgaaaaa atagtaagta taaaaatagg ctaggaatcg gttttctatg
    54361 taaaacaaga tttagttatg ctaaaattga tggaagcaga cacatgaatg agtagaaaag
    54421 ttagatgctg tgacatgtgg atgttagact atgatctatt ttgatagata gagctaaggg
    54481 aagaaaagga gtggatttca tggaagtaaa gcagttgcca aaacgagaag aattgcctga
    54541 aaatttaact tgggacttga ccaagatctt ttcaagcgac caagagtttg atgagaaata
    54601 tttggaatta tcagaagagt taaaacaatc tgaaaaacac aaaggaacac ttgatcaagg
    54661 cgcttctcaa tttttaaatg cgattgaatt cgtattgagg gtttatcgcc aaactgaagt
    54721 catttatgta tatgcgcacc ttaaaaacga tcaagacact ggaaatacag attaccaagc
    54781 gctttatgca agagcaagca gtctgttttc gaaagttagt gaagccgttt cctggtttga
    54841 accagaaata ttgcaattgt cagatgacca gatttggcaa tatttcaaag aagaaccaaa
    54901 attggaagtc tatcgccatt atatccagca aatagtagat aatcgagccc atgtcttatc
    54961 tgctgagcag gaatctcttc ttgctggagc aggtgaaatc tttgatgctt caagtgatac
    55021 atttgctgtt ttgaataatg cagatctagt ttttccaacg attgaaggag aaaatggtga
    55081 aatagtccaa ttatctcatg gcgtgtatgg tcagttgcta gaaagcacgg atcgaagggt
    55141 gcgcgaagca gcatttaagg ggttgtacag tgtttacgaa caatttagaa atacatttgc
    55201 ttctacttta ggcacacata taaaaggaca taattttaaa gcgaaagtcc gtaattacag
    55261 ctctgccaga gaagcgtctt tgagcaataa tcatattcct gaaagtgtat acgatacttt
    55321 ggtagacgtg gtaaacaagc atttgccttt gttacatcga tacatggaat tacggaaacg
    55381 tttattagaa gtggaaaaac tgcacatgta tgatctttat acaccggtct taggggaagc
    55441 tccaattacc tttacgtacg aagaagcaaa agaaaaagct ttagaagcac tgaaaccaat
    55501 gggtgaagaa tacatggcca tcgtagaaaa agcattctct gaacgttgga tcgatgttgt
    55561 cgaaaataaa gggaaacgaa gcggtgctta ttcttcggga agctatgaca caaatccata
    55621 tattttattg aattggcatg atacgctgga tcagctattt acgcttgtcc acgaaatggg
    55681 acatagtgtt catagttatt tcactcgttc gaaccagcct tatgtgtacg gcgactactc
    55741 catcttttta gcagaaattg cttcgacaac gaatgaaaat atcctaacgg agtatttatt
    55801 ggaaacagaa aaagaccctc gtgtacgggc ttatgtactc aaccattact tggatgggtt
    55861 taaaggaaca gttttccgcc agacacaatt cgctgaattc gagcatttca tgcatacgga
    55921 agatgaaaaa ggtgtgccat tgactagtga atacctaagt gatagttatg gtaaattgaa
    55981 tgcaaaatat tatggtccag cagtcgaaga agacccagaa attaaattcg aatggtcacg
    56041 gataccgcat ttttattata attactatgt tttccaatac tcgactggct tttctgctgc
    56101 ttcagcactg gcgaagaaaa tactaaacca ggaaccagag gcactagaga actacttggc
    56161 ttacctaaaa gcaggtaaca gcgattatcc tgtggaagta atgaaaaaag caggagttga
    56221 tatgacacag gctgcatata ttgaagatgc aatgtcgatg tttgaacaac gtctaaatga
    56281 attagaagaa ttgatcgatc gtttataagg ctttctattt ttgattttct cgaatagaaa
    56341 cgaaaaaaat acgtcggctc tcttgtaagg gagtcgacgt attttttta
//
LOCUS       DARPZF010000013        52880 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.013, whole genome shotgun sequence.
ACCESSION   DARPZF010000013 DARPZF010000000
VERSION     DARPZF010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52880
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.013"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(21..1517)
                     /gene="lysS"
                     /locus_tag="SLE65_001076"
     CDS             complement(21..1517)
                     /gene="lysS"
                     /locus_tag="SLE65_001076"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEI8448384.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1628..2632)
                     /gene="dusB"
                     /locus_tag="SLE65_001077"
     CDS             complement(1628..2632)
                     /gene="dusB"
                     /locus_tag="SLE65_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEI8448385.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2633..3520)
                     /gene="hslO"
                     /locus_tag="SLE65_001078"
     CDS             complement(2633..3520)
                     /gene="hslO"
                     /locus_tag="SLE65_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEI8448386.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3737..5848)
                     /gene="ftsH"
                     /locus_tag="SLE65_001079"
     CDS             complement(3737..5848)
                     /gene="ftsH"
                     /locus_tag="SLE65_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEI8448387.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5938..6483)
                     /gene="hpt"
                     /locus_tag="SLE65_001080"
     CDS             complement(5938..6483)
                     /gene="hpt"
                     /locus_tag="SLE65_001080"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEI8448388.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6483..7928)
                     /gene="tilS"
                     /locus_tag="SLE65_001081"
     CDS             complement(6483..7928)
                     /gene="tilS"
                     /locus_tag="SLE65_001081"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEI8448389.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8048..8518)
                     /locus_tag="SLE65_001082"
     CDS             complement(8048..8518)
                     /locus_tag="SLE65_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HEI8448390.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8564..8989)
                     /locus_tag="SLE65_001083"
     CDS             complement(8564..8989)
                     /locus_tag="SLE65_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEI8448391.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9056..9325)
                     /locus_tag="SLE65_001084"
     CDS             complement(9056..9325)
                     /locus_tag="SLE65_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEI8448392.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9336..10931)
                     /locus_tag="SLE65_001085"
     CDS             complement(9336..10931)
                     /locus_tag="SLE65_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEI8448393.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10946..14467)
                     /gene="mfd"
                     /locus_tag="SLE65_001086"
     CDS             complement(10946..14467)
                     /gene="mfd"
                     /locus_tag="SLE65_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEI8448394.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14484..15044)
                     /locus_tag="SLE65_001087"
     CDS             complement(14484..15044)
                     /locus_tag="SLE65_001087"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEI8448395.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15397..16371
                     /locus_tag="SLE65_001088"
     CDS             15397..16371
                     /locus_tag="SLE65_001088"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEI8448396.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16541..17941
                     /locus_tag="SLE65_001089"
     CDS             16541..17941
                     /locus_tag="SLE65_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HEI8448397.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18019..18741)
                     /locus_tag="SLE65_001090"
     CDS             complement(18019..18741)
                     /locus_tag="SLE65_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8448398.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18820..19326)
                     /locus_tag="SLE65_001091"
     CDS             complement(18820..19326)
                     /locus_tag="SLE65_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEI8448399.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19449..21248
                     /locus_tag="SLE65_001092"
     CDS             19449..21248
                     /locus_tag="SLE65_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HEI8448400.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21316..22890)
                     /locus_tag="SLE65_001093"
     CDS             complement(21316..22890)
                     /locus_tag="SLE65_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HEI8448401.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23145..23654)
                     /gene="mreD"
                     /locus_tag="SLE65_001094"
     CDS             complement(23145..23654)
                     /gene="mreD"
                     /locus_tag="SLE65_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEI8448402.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23658..24512)
                     /gene="mreC"
                     /locus_tag="SLE65_001095"
     CDS             complement(23658..24512)
                     /gene="mreC"
                     /locus_tag="SLE65_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEI8448403.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24667..25305)
                     /locus_tag="SLE65_001096"
     CDS             complement(24667..25305)
                     /locus_tag="SLE65_001096"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEI8448404.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25306..25956)
                     /locus_tag="SLE65_001097"
     CDS             complement(25306..25956)
                     /locus_tag="SLE65_001097"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEI8448405.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25969..26868)
                     /gene="rsgA"
                     /locus_tag="SLE65_001098"
     CDS             complement(25969..26868)
                     /gene="rsgA"
                     /locus_tag="SLE65_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEI8448406.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27033..29102)
                     /gene="pknB"
                     /locus_tag="SLE65_001099"
     CDS             complement(27033..29102)
                     /gene="pknB"
                     /locus_tag="SLE65_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEI8448407.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29099..29839)
                     /locus_tag="SLE65_001100"
     CDS             complement(29099..29839)
                     /locus_tag="SLE65_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEI8448408.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29852..31210)
                     /gene="rsmB"
                     /locus_tag="SLE65_001101"
     CDS             complement(29852..31210)
                     /gene="rsmB"
                     /locus_tag="SLE65_001101"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEI8448409.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31210..32148)
                     /locus_tag="SLE65_001102"
     CDS             complement(31210..32148)
                     /locus_tag="SLE65_001102"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEI8448410.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32141..32632)
                     /gene="def"
                     /locus_tag="SLE65_001103"
     CDS             complement(32141..32632)
                     /gene="def"
                     /locus_tag="SLE65_001103"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEI8448411.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32647..35055)
                     /gene="priA"
                     /locus_tag="SLE65_001104"
     CDS             complement(32647..35055)
                     /gene="priA"
                     /locus_tag="SLE65_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEI8448412.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35308..35613)
                     /locus_tag="SLE65_001105"
     CDS             complement(35308..35613)
                     /locus_tag="SLE65_001105"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEI8448413.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35618..36232)
                     /gene="gmk"
                     /locus_tag="SLE65_001106"
     CDS             complement(35618..36232)
                     /gene="gmk"
                     /locus_tag="SLE65_001106"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEI8448414.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(36719..37003)
                     /locus_tag="SLE65_001107"
     CDS             complement(36719..37003)
                     /locus_tag="SLE65_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448415.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37021..37911)
                     /locus_tag="SLE65_001108"
     CDS             complement(37021..37911)
                     /locus_tag="SLE65_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HEI8448416.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(37931..38149)
                     /locus_tag="SLE65_001109"
     CDS             complement(37931..38149)
                     /locus_tag="SLE65_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEI8448417.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38119..39819)
                     /locus_tag="SLE65_001110"
     CDS             complement(38119..39819)
                     /locus_tag="SLE65_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HEI8448418.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40085..40858
                     /locus_tag="SLE65_001111"
     CDS             40085..40858
                     /locus_tag="SLE65_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448419.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(40939..41508)
                     /gene="thiT"
                     /locus_tag="SLE65_001112"
     CDS             complement(40939..41508)
                     /gene="thiT"
                     /locus_tag="SLE65_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEI8448420.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNSWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(41574..41676)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(41682..42653)
                     /locus_tag="SLE65_001113"
     CDS             complement(41682..42653)
                     /locus_tag="SLE65_001113"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEI8448421.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(42747..44120)
                     /gene="glmU"
                     /locus_tag="SLE65_001114"
     CDS             complement(42747..44120)
                     /gene="glmU"
                     /locus_tag="SLE65_001114"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEI8448422.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(44623..45441)
                     /gene="purR"
                     /locus_tag="SLE65_001115"
     CDS             complement(44623..45441)
                     /gene="purR"
                     /locus_tag="SLE65_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEI8448423.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(45608..46432)
                     /locus_tag="SLE65_001116"
     CDS             complement(45608..46432)
                     /locus_tag="SLE65_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEI8448424.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46405..47085)
                     /locus_tag="SLE65_001117"
     CDS             complement(46405..47085)
                     /locus_tag="SLE65_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEI8448425.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47108..48046)
                     /locus_tag="SLE65_001118"
     CDS             complement(47108..48046)
                     /locus_tag="SLE65_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEI8448426.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48291..49154)
                     /locus_tag="SLE65_001119"
     CDS             complement(48291..49154)
                     /locus_tag="SLE65_001119"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HEI8448427.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(49296..51869)
                     /gene="mprF"
                     /locus_tag="SLE65_001120"
     CDS             complement(49296..51869)
                     /gene="mprF"
                     /locus_tag="SLE65_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HEI8448428.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52010..52816
                     /gene="proC"
                     /locus_tag="SLE65_001121"
     CDS             52010..52816
                     /gene="proC"
                     /locus_tag="SLE65_001121"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEI8448429.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
BASE COUNT        14659 a        11480 c         9505 g        17236 t
ORIGIN      
        1 cttagacagc ttttattcga ttatctcatt gttgggaata gcaaaacatc ccgaattgat
       61 tgtgcatcag ttagcaacat tactaatctg tcgatcccga tgcctagacc accagttggc
      121 ggcataccgt attctaaggc ttccaagaag tcttcgtcta caccgtgagc ttcgtcattt
      181 cctagttcac gttctttttc ttgcgcttcg aatctttctc tttgatcaat tggatcgttc
      241 agttctgtaa aggcattagc aaattcgcgc cccactatga atagttcgaa tcgatctgtg
      301 aatcgaggat cttctggatt tttcttcgct aaaggcgaaa cttcgactgg atgtccgtat
      361 acaaacgtcg gttgtgtcaa tgtttcttca acaaatgttt caaagaattc attgataaca
      421 tgtccgacac ccatagcttc ggttacttct acattgtgtt tttcggctaa agctaatgct
      481 tcttccaatg tcatttcttg ccagaagtct acaccagttt gttctttgat tgcatctacc
      541 atatggatgc gtttaaagtc actttctaag tcgacagctt gtccatcata tgtgattttt
      601 gctgttccta gtactttttc agctgcgtta cggataatac cttctgtcag attcattaca
      661 tcattgaaat cagtatatgc tgtgtatgct tctaacatcg taaattctgg attatgtgta
      721 gtatcaattc cttcattacg gaaaacgcgg ccgatttcat aaactttttc cattccgcca
      781 acaattagtc gttttaaatg aagttctagc gcaatacgca aatataaatc aatgtccagt
      841 gcattatgat gcgtgataaa tgggcgtgcg gcagctccac ctgcctcatt gtgcaatact
      901 ggtgtttcta cttcaatata gccattgcca tctaaatagc gacggatttc gctgataatt
      961 tggcttcgtt tcataaatcg gtcaaagctt tcgcgattac tgattaaatc caagtagcgt
     1021 tgtctgtagc gttgttcaat attcgttaag ccatggtatt tatctggcag tggacgaagt
     1081 gcttttgaca aaatcgtgat ttctgaagct ttgatagaaa cttcgcctgt gtctgttttc
     1141 atgatttgtc cagttacacc aaagaaatct ccaaggtctg catgtttgaa tacttcatag
     1201 gcctcatcac ctacttggtc ttttcttaca taaatttgaa tttggccttc acgatcttgt
     1261 agatgcgcaa atccagtttt cccttttcct cggcgagtca tcatacgacc agctacacta
     1321 gcggtcaatc ccatttctgc tagttcttct tttgttcttg gatcaaatag ttcatgcaat
     1381 tcttctgagt tgtgcgtgcg ttcaaatcgt tttccaaatg gatcgattcc atcttcacgc
     1441 aattgttcca ttttttgacg acgtacaagc atttgatcat ttaaatcttc tacttgatgt
     1501 tgttgttcct gtgtcacaaa agttcctcca ttctcatgtt aatctctttc ctataatgcc
     1561 aatgaaacac aaaaaaagca agccgaactt ggaatttcgg cttgaaaatt cacgaaaaac
     1621 ttagaaatca caacgtttgt ttcaatagta ctttttccgc tttttctaca aattgatcca
     1681 gcaggtcatt gatttcttgc tgtttttctg tctgattgat tgctactttc actttcgctg
     1741 ctcgaggaat cccttttaaa taataagccg catgtgttct gaattctcta caagctactt
     1801 tttctccttt gagatctgct aagcgttgta aatgaagttt agctgtagca attttttcgg
     1861 ctggtgttgg ttcaggaatc agttctcctg tttcgagata atgctgtgtg cggtgaatca
     1921 tccatggatt gcccagcgct gcacgaccaa tcatcacacc gtctgcaccg acatagtcaa
     1981 gcatccattt tgcatcttct ggcgttttga catccccgtt ccccataaat gggatcgtca
     2041 aatgtttttt cacttctttc aatacttccc agtccgcttt tccttcatac atctgaaccc
     2101 gtgtacgtcc atgcatagcg atggcacttg ctccagctga ttgtgctgct aatgcatttt
     2161 ctacagcaaa gacgtgctct tcatcccaac caatacgcat cttgattgtt actgggatat
     2221 ttactgctga agaaacagct tggaccattt cgtatacttt ctcaggatct aaaagccatt
     2281 ttgctcctgc ttctgctttg attactttat ttactggaca gcccatattg atatctatta
     2341 tatcggcagc tgtgttttct tcgacaaatt gagcagcttc aactagacta tctttatttc
     2401 cgccaaatat ctgtaaactt aatggatgtt ctgtttcttc aatgtggagc atctctaaag
     2461 tttttttgtt tctgaaatga ataccttggt cactgatcat ttcacatacg actaagcccg
     2521 caccaaattc tttgacagtg actcgaaatg ctgaatttgt tattccagcc atcggtgcaa
     2581 caacgacacg attagggatt tccacattgc caattttcca tgtgtgttcc acttaaatcc
     2641 ctcctaaggc ttctttcttc aatccatcta attcttcttc gctatacttg tatttgttat
     2701 tacagaaaga acaaaccgct tctgcaccgt gatcttcgtc tatcattgct tggatttctt
     2761 ctgcacctaa cgcgataatt gcttctgcaa atttttcttt tgaacagtca catttgaatt
     2821 gaacaggcat tttttccaaa atgttcaatt cttctgtacc aagcaatcct ttcaatattt
     2881 cttctggtgt ctgtccttca tctaagaggg tagagattct tggtgtcgtt tttaattgtt
     2941 cttcgatctt gctgattgtt tcttcatcgg cacctggcat gatttggatc atgaatcctc
     3001 ccgccgtctt gatgctgtcg tcagtattga ccaatacact cagtccaaca gctgaaggga
     3061 tttgttctga gatagcaaga tagtaagtaa aatcttcagc gatttctcca gaaacaatcg
     3121 gcgtttgccc agaaaaaggt tcttttaatc ctaagtcttt tgtgacagta aacattcctt
     3181 gtgttccaac tgctccccgc acatcgattt taccttcact atttagagga agactgagat
     3241 gcggattttt gatgtaacct ttcacatctc cctttccatt tgcatctact acaattcctg
     3301 ttgctggacc atcgccttgg attcgaacag ttagtttgtc ttctcctttg agcgtcgcac
     3361 caagtagcag actaccgacc aatgtccgtc ccaaagcagc tgaggaggtg tgccaagtat
     3421 catgacgtct ttgtgcctcc gctacggtat ttgttgcttg aacggcgtat gctcggacga
     3481 atccgtcgtg agcaagtgcc ttaaccaaat aatctttcat ttgttatgta ctcctttttc
     3541 cgtttttaaa ctcatagtga atcatactag caactactgc ttttttcaac tttggaatgc
     3601 ttcttttaaa aataattcag aatcatctag aaaacaggac atcaccctat ttacaactta
     3661 aataaagaaa tctcccgaaa accggttttt gttccggttt tcgggagtca tatcagatca
     3721 attgacctat atttttttat ttgtattgat cgtctgaatg attatcttct gattgttgag
     3781 aatctgaatc atgttctgct ttattttcct cattcagttc atgttttgct tcttcaaaat
     3841 cacgtttttc ttccgcttgt ttttcagcgt ctttttcttc caaagcacgt tttgcttctt
     3901 caaaagtttt cgcttctttt tcgcttggat aatcatttga ctcagtacct tcaggcatca
     3961 caccgtgttc aaacaatgac ttgattgctt tggcatccaa tgtttcgaat tccaaaagtt
     4021 tttcagcaat cagtttatgc tgtgcacgat gagcttcgat gatttctcga gctttatcat
     4081 gagcttccat caagattttt cgtacttctt gatcaatctc gaaagcgact tgttccgagt
     4141 aagcttttgt ttgaccatag tcgcggccaa caaacacttg atggtttcct tcatattgaa
     4201 caggacctaa acgatcactc attccatatt ctgttaccat gcttcgtgct agagctgtcg
     4261 cttgctcaaa gtcattggaa gcaccagttg attggacatt gaagatgatt tcttcagctg
     4321 tacgtccacc aagtaagcct acgatttgtt caaacatatc ttctttcgtc atcaagaact
     4381 gatcttcttt tggtaaagcg atcatatatc cgccggcgcg tccgcgaggg atgatcgtta
     4441 ctttgtggac gacccgagcg cgactcaata ctaatccgac aatcgtatga ccagcttcgt
     4501 gataagcaac catttcgcgt tcttttttgc tgattacgcg atctttttta gctggacctg
     4561 caatcacgcg atcttccgct tcatcgatat cagaagcatc gattttcttt ttatttcttc
     4621 tagcagctac taacgctgct tcattcaaga cattttctaa atctgctccg gcaaaacctg
     4681 gtgtctgttg agccacaact ttcaagtcaa cgtcatctgc catcggttta ttccgtgcat
     4741 ggactcgcaa gattgcttca cgacctttta catctggacg tccaactaaa atctggcggt
     4801 caaaacggcc tggacgtagt aacgctgggt ctagtacatc agaacggttg gttgcagcaa
     4861 tgacgattac tccttcattt ccgtcgaagc catccatttc tacaagcaat tggttcaatg
     4921 tttgttcgcg ttcatcatgt ccgccgccca taccggcacc acgttgacga cctaccgcat
     4981 caatttcatc aatgaaaatg atagctggtg cgtttttctt cgctgtttca aacaaatcac
     5041 gaacacgact tgctccaaca ccgacaaaca tttctacgaa atcagaaccc gagatcgagt
     5101 aaaacggtac tccagcttct ccggcaacag cttttgctaa taaggtttta cctgttcctg
     5161 gaggtccttc taaaagtaca cctgccggga tacgggcacc taattcaaca aatcggcgag
     5221 gatctttcag aaattcaaca acttcaacta gttcttgttt ttcttcttcc gcacccgcta
     5281 catcagaaaa acgtacgcga ttagcttttt tgtctgcttc tttggctttt gatttaccaa
     5341 agttcatgac acggccgcca ccgccaccgc cgccgccttg ttgtcccatc atcatgtaaa
     5401 agaaaaagat gatgattacg attggcaaga agctaagcaa tagggaaacc catataccgc
     5461 tgcttgattc ttcttttact gttgtagcaa ctttgttttc ttttgccagt tctgttactt
     5521 ggctcaatgt tgtatcattt ggcaaaatga ttgttgtgaa atgggtagta gtcgtatctg
     5581 ttgaacctaa gatagctaac ccaccgctgt tagcgacggt ctgctgttct ttgtattcac
     5641 cagtgatctt atatacacca tttgcaggct gcacttcaaa ttctttgatc ttgcctgctt
     5701 gtagttgttc tgtgaatttt gagtactcga tatctgacga tcgctggccg ttattaccaa
     5761 aaatgaaata aacgaccatt accatcgcta agattacgag gacataatac aaggcatttt
     5821 tcatcatgcc gttgttcttt ttgttcatag ttgccctccc taagcgtcaa tttaatttaa
     5881 cagtttttta tcaatcctga ccattctatt gtaccataat ttaattgaga tacagcatta
     5941 atttgattga taaacactag gtttcaatac accgatgtac ggaaggttac gatatgcttc
     6001 tgcataatcc aagccataac cgaccacaaa ttcatttggt acgttgaagc caacataatc
     6061 tgcttcgata tttactactc ttccttcagg tttgtcaagt agtgtaacaa ttttgactga
     6121 ttttgctttg cggtatttga aaagatccac taaataagca agtgttcttc cgctgtcaat
     6181 gatatcttca acgatcaaca gatcgcgacc ttctacattc gtatctaagt ctttgacgat
     6241 ttttacttcc cctgacgaga ctgttgcatt cccgtagctt gaaacatcca tgaaatccaa
     6301 ttccaaatac gtatcgatag aacgaacgat atctgccatg aatggtaccg ctccttttaa
     6361 gacacctact actaggggat tggtgttttg gtaaatttct gttaactctt tgcctagttc
     6421 tttgcaacga acttgtatct cttcttgtga gatcaaaatt ctctcaatat ccttttccaa
     6481 catcaggttc tccttccaat tgcttctttt tgatatttgt aaagaagtat gtagtgtatt
     6541 ttatcagttt cttcacgaat actcaaatat gaaaaggcaa aaggtatcaa gctatatata
     6601 tttcttttgg catctgtaat gatccaagca tgctgccttt gtgaattagg tactttctga
     6661 tcgataaaat atctagatac tttttttgtg agattctctg ttaatttaat gcggtctcct
     6721 gcttttcttt tttcgacata cagttgcaca tcagcaggaa tccaaatgtc atgagaaaat
     6781 agagaccatg aatctgttgc tttgatgtcc cctgcatttt caggtttgac cagaccaatc
     6841 cattctgttt cattcaaata tattccttgt tctggaatca gcaacaagcg ctggtcttct
     6901 gtctggctag ttgcttgttt ttctttttta gagagtacaa caaaatgata ctctcttttc
     6961 agtatccaat tattgccaat actgagttgc cattggcttt ttttctgttg ccactggtct
     7021 aaaatcgact ccatttgttg ttctttcaaa ataattcctg tttttgagaa tgctttgtcg
     7081 aaaaaggagt aaaaaaaata gtatcgttca gcatctgtca tttcttcaat catttctgca
     7141 gaaaatcgaa attgttcctc ccactgttcg acttcctttt cgatcaactg tcccatatat
     7201 ttttgaatga cttggtctgc ccattggatc tgttgcgaaa attgctggaa atgtctcaac
     7261 gcctgtgtat tttcttgttt caattgagga actaccaaat gacgaagccg atttctctgg
     7321 atatctaaca attggtttgt ctgatcctca aagtaaacaa gctgcgattc cgctgcataa
     7381 gtatataggt cttctttgct aaaactcagc aacggacgaa tcagtctgcc cgtagcaaat
     7441 ggttgtactt ctttgattcc agaaaaagta tttaactgtc ccccacgaac gattttcatt
     7501 aacaccgtct cgatttgatc atctccgtga tgagcagtca tcaacgtgtc atattgtcct
     7561 tcttccatca cgcgagtgaa ttcttgataa cgaaagttac gagcttctgt ttctatggcg
     7621 gatttggctg gatcttccca aatacttaca tataaaggga gattcttctc ttcacaatat
     7681 gagcgaagat aggcagcttc ttctgctgat tcttctctta attggtgatt gatgtggacg
     7741 atacctaaag aaaaaccgat ttggcgttgc acttgtaaaa gtaaatggag caaaaccatc
     7801 gaatcaacac cacctgatac cgctgctaaa attctcgatc cttgttgcca gaatccttgt
     7861 tcattcccgt gccgaataaa tgactgctgt aatagcggtg cttttttccc gcctttttca
     7921 acgttcatcc tttccacacc ctttcttcct aaaaaaaaga gagcgggaaa acgtctaaaa
     7981 cgacaattaa cctgccctct gttgatacta tgacccaaat agtcgcacta tcattatttg
     8041 cggcttttta gctgcgacgt ccgccacggc caccgcgctt tccttctgtg tttcgcttca
     8101 atgaagataa gcggtcatcg ctatctttca aaaatgaact catcaatgaa tcgaagtctt
     8161 ctttttgagc tgaaggttga ctgcgagaaa aagatttttt ctgtgctgga cgatttcggt
     8221 tgtcacgggg atctttttgt tgatattttt taggacggct ttcttctcca gattcagcag
     8281 gttgttcctg cgctttccgg atagatagtc cgatttttcc atcatcattt actgaaataa
     8341 ctttaactgt tacttcatct cctacactta aaacatcatg gatgtctttt acatagccat
     8401 ttgacacttc gctaatatga actagacccg tttttccagc acctagatca ataaacgcac
     8461 caaaatttgt gattcctgat acttttcctt gcagttttgc tcctacctcg attgacataa
     8521 aaaaaatgtt cctcctaatt atttcccttt tttatattcc tgcttatttt gcagttgtag
     8581 aactagttga ttgatctgtt tcatttgtcg agctgtctgt atttgattct aatataggat
     8641 aaactttttc accgtctttt gagtaaaaga atttgcttct ggcaagttta gctacatact
     8701 catcatcttt cagcaatgaa acatcttggt gcagctgatc aacgtctgcg ttgacttctt
     8761 tcatttcagt atttgcttcg actctcaatt cgttcaattg atgcatcctt tgcatgtcat
     8821 ggaaaatctg cacacctatt atcgcgaaaa tgaccaaagc accaacaaaa attgcagcca
     8881 gtctgcgtct tcgaaaaatc agttgacgtt gttgttgctg aaattcagca tactttttct
     8941 ttgcatattc cgtatctagc gcagcgattt tattgctttt tttcgtcact tggattcgct
     9001 ccaatctttt tgattgtctt tttcattata ccaatatcgt gaaagcttgt ctaatctatt
     9061 tctctagtgt ttctgtgcga ttttcagaaa taatttcgta cattttttgt gcatcttctt
     9121 ttttggttga ttcatgtaat tccgtaattt tcacttccaa cgttttgttg ccaaactgga
     9181 ctttcaaaat atcgcctact ttgacatcac tggaagattt cgccaattta ccgttgattt
     9241 gaattcttcc tttatcagct acttcttttg ctactgatcg tcttttgatg attcgggaaa
     9301 tttttaaaaa tttatctaat cgcatatctt attcctcact ttttaatttt tttatttaat
     9361 cgcaggattt tcttaccaaa aggcaacatt agccattctc gtactgtaaa cagacgaaga
     9421 cgaatcactg cataaatgaa cacagaagcc ccgatcccaa ctcctatcac gctgacaaaa
     9481 aaagcagtgg aacgatgagt tacaggacca aatactatat tcaatacacc ataatacagc
     9541 agcagtacta ctgtcataca aagaaggctg aacatcaact tccgtccaaa atgccgttct
     9601 ttccaaaaag catttagctc ttttgtttca attcgaacaa aataccaaag cgtcacacct
     9661 aatcctaaaa gggtagacag gcttgcacct gctgttccta ataaaccggt cagaaaagaa
     9721 gtagtcaatc cttttaccaa tagtccccat cctgcgcctt ttaaagaagg gcgaaacgag
     9781 ttcttgcttt gagcaatact ttgataagct tggatgactg cagtgaaagc aatggaaaaa
     9841 acaaataata caagcgctgc atttcccgca taatctttaa acaacgcata attgatataa
     9901 gggagcagca aggctaatcc caaagacgca gctaatgcta aagcggtcgt caatctaaga
     9961 tagattttgg ctgtctgtaa aaactgacga tagatccggt tggtcaaatg acgagtcaac
    10021 gcaggcagga atgtcgcact taatgcagtg gcaatcacta aacctaattg tactaaaggc
    10081 tgacctcgat catagacccc ttttgctatc ttcgcaccgt attctgacag tccgtaaact
    10141 tccaaagcat tttttacaaa gaaagagtcg atcagctgga aaaagataag caatccacta
    10201 taaatcgaaa ccagtccgcc ttctaccaga aaacgccgga tcaagggctt tgacggctgt
    10261 ttgaacaatg gaaaccgtcg gaagcttaac gctcctccat gaatcttttg ttcatagtag
    10321 tgaaggatcc catatgcgca taaaccgcca aaaacagctc cactcattgc tgccgtccct
    10381 gtttggtaca ccgtccatcc aagctttcta aaagcaaacg cactacagac aatcacaaaa
    10441 acacgaacga actgctcaac tacttgagaa acagcagttg gttccatcaa gaatcttcct
    10501 tggaaattcc ctcgataaaa agatagacca ggcatcagca aaaaggtaaa ggaaactact
    10561 tggatcagcg gtttcaattg tatgtctccc atcatccaag caatccagct gctaaatgca
    10621 aagacaaaca accacaaaaa gacacctgtc caaaatacta agggataaag attttgcaaa
    10681 gcttgctttc gctcgaaagg attctttctt tctgcaacgt actttgatat gaactgcgga
    10741 agaccggata aagctaaagt cattgctatc ccataaattg gataaacttg ctgataaaca
    10801 taaaaacctt cgtcgccgac taagttttgg aggggaattc ggtaaagggc acttaatact
    10861 tttgctatga aagaagcaat cgtcaataca aatgctcctt gcatgacgcg ccgcatttct
    10921 ttatgatcca aatcattgct ccttcctacg ctgacagata tttttgctca cgcaacgctt
    10981 tgacaaactt ttggatttcc tgaagccata ctgcttcttc catttggttg gggatcgtca
    11041 agcgtatcac catctgttct ttttcaacgc ctagactggc ttttagtttt gtcgctgtca
    11101 gtgcttcgaa taactgttcc acactatagc gttttgttcc aactttactt agagtaaaga
    11161 ctatatgcgc ctcctgtttc cttatcgttt ctaggagcgc tcgatcgcca tccattttga
    11221 tctgcccaat tgtcaagaga tgtgctactt cttctggata ttctccaaaa cggtcgagca
    11281 gatcatcttc tagttcatct agcatttctt gcgaatcaag ttcacgaatt cgtttataga
    11341 tctcgatttt ctgccgttga tctgccacgt atgtttcagg tagatacgca tcgacaccga
    11401 ggtcgatctc aacagtggtc ttctccactt gactattctt tccttgttta cgagaaacag
    11461 cttcgcttag catttgagaa tacatatcga aaccgactgc atcaataaat ccatgctgct
    11521 gagcacctaa gagattacct gcaccgcgaa tggaaagatc ccgcatcgca atcttgaatc
    11581 cagatcccag ttctgtaaaa tctttgattg cctgaagacg tttttcactg acttcgttaa
    11641 ggatcttctg ctgctcatac ataaagtaag catatgcgac acggctgctt cttcctaccc
    11701 gccctcgcaa ttggtataac gtggataatc ccatataatc agcgttctca acgaacaacg
    11761 tatttgcgtt cgggatatct actcctgttt caatgatggt tgtagtgaca agaacatcat
    11821 attgaccttc aataaattca aaaagcgtat tttctaattg cgcctctgtc atttgcccat
    11881 gagcataacc gatccgtgct tccggaacga gttcttggat ttcttctact ttttgttcga
    11941 tcgtttctac ccgattatat aaatagaata cttgtccacc tcgtcccatt tctcgatgga
    12001 ttgcttcgcg aatagcccca ggattttttt ccataacata cgtttggatc ggataacgat
    12061 tcgcaggcgg tgtttcgatt actgaaagat cccgcacgcc taacatcgac atatgcaaag
    12121 ttctcggaat cggtgttgca gtcagagtca aaacatccac ttgtgcacgt aactgtttca
    12181 atcgttcctt atgttttaca ccaaaacgtt gttcttcgtc aatgatcagt agacccaaat
    12241 cgctaaattc aatatctttt gacaaaattc ggtgggttcc tacaacaata tcaacttgac
    12301 ctgtacgcag ttgttcgatg gtttcttttt gttgctttct tgttctgaaa cgacttaata
    12361 gcccgatatt tacggggaaa ccttcaaatc tttccagcat cgtttcatag tgctgctgtg
    12421 ccaagatcgt tgttggaact aaaaaggcta cttgtttgct ttcctttatc gctttaaagg
    12481 ccgctcgaag cgctacttct gttttcccat aaccaacatc acctacgagt agtcgatcca
    12541 ttggtttttc tttttccata tcccgtttga tctccgctgc acttctcaac tggtcatcag
    12601 tttcagagta ggggaaggca ttttcgaatt ctttttggta ggcgtcatca ggtccaaaag
    12661 catatccttt ttctgactct cttgcggcat ataatttgat tagatcgtca gcgatatcct
    12721 cgatttttga agagactttt cgcttggttt tcgtccattc acttccgcct agcttattga
    12781 tgcgaggcgc tttggcttca gaggcgacat atttttggat cagattcagt tgagtaacag
    12841 gaataaacag tttgtcgtcg ttttgataca aaatagtcat atagtcttgg tgaacgccat
    12901 ctacttctag cgtttccatc ccaatgtatt tcccgatacc atgattggca tggacaacgt
    12961 aatctcctgc ttttaactca ttatagcttt tcaatcgctc tgcgtttgtt actgtttgac
    13021 gtctcgtttg ttttttcgtc gttttttgga aaatttcttt ttctgtgata gctactattt
    13081 tttcttgagg aagttcaaaa ccagcctgca aagctccttc aactaattgt acctgtcctc
    13141 tgatcaatgc atttttttct gtttctacta ctaatatgtc ttcatctcga agcatttgtt
    13201 ctgctttgcg tattctgtcc tttgtcggaa taaagatcac aacagtctgt ttttgcttgc
    13261 gccaacggtc catttctgtt ttcagcaatg gcatttgtcc gaagaactgt tgcatcgtcc
    13321 gatattgaaa attatggatt gcttggaaac gaagatttcc catccctttt tggaagagtg
    13381 agaaaaaggt tgtggtgaac ttttccttct gcacgatttt ttgtatatct gctgaaaatg
    13441 tctgctcaga aaacacccgc aattcgctga ttttttgagt ctgccattct gccgcttccc
    13501 tttcgatttc ccgatttgtt tccatgattc gctgataatc atcaacgact agtaaactat
    13561 ttgaagggaa ataatccaag atcgtcacag attcttggta aagaagatct gagtagaatt
    13621 ttgcttcttc tgtcgggaca cctgcttgcc agcttgaagt cagctgaccg aagtaatctt
    13681 gcaaaaactc gcggtctgct tcttctgtgg tcgcagcaag ccgtttttct agcatttttt
    13741 gcatttgctc tattccatgt tctagatcct ctggtccgta gacttgttca ctcgttgggg
    13801 aaacccagat ttcttccgtt ttttcgattg agcgttgtgt ttctgcttca aaataccgca
    13861 tagaatctat ctctacatca aatagttcta cacgaacagg ataggttgtc gttaacgggt
    13921 aaatatcgat aatgcttcct cgaatactga attctcccgg ttttgcgacc atctcttctc
    13981 gtacatagcc catcaaagtc aattggcgag gaagattttc cacgtctatc tcatcaccaa
    14041 tatgccaatt caattgcgcc tgtagccaag ttttcttatt cggcagtcgt ttgtgcaaag
    14101 atgcgactgg caacaaatag atacctgctt ttttttcttg aagtgcgtta agcgttgcaa
    14161 ctctctcgcc tcgcgcttct ggagaagaaa aggccatttc agcagaaagc acttcatcca
    14221 ctggaaataa atggatctga tcttgcggaa tcacatgttg cagatcttct gctaactgat
    14281 tcgcataata caaatttggc atcagaataa tcatgttttt atttgttttc ttaaacgctc
    14341 gagcaaatag aagtgttttc gctgagcccg ctaatcctgt gattagttgt ctaggcattt
    14401 tttcttctaa attgctgacc cattctttta cttgcggatc ttttccgact aattgaataa
    14461 tatccattcc ttttcctcct tcctcaattg aatcgattca tcgcatccac gaacgaatgc
    14521 ccttctatga gatattcgac tgctttaaca gattgacaca tgctttcttc tatcaaaggc
    14581 tgattttctt tgctgaaagg actaagcaca tgctggacta ctgttttttt cccttctggc
    14641 ctgccgattc ccaccttgat tcgatcaaag acattcgtat tcaaatggga aataatactt
    14701 ttgataccgt tatgcccgcc ggcacttccc ttttgacgga gccggatttt tcccactgcc
    14761 agatccaaat catcgtagat tacgactaat tcctctggat aaatcccaaa ataagtcatt
    14821 agtgggccga ctgcacgacc agattcattc atgaatgttt gtggtttgac taaaaggatc
    14881 ttttctccat tatgaaaaaa ttcggcaact tctgcttcga acggattttt tttgaaagta
    14941 gcttgatgct cgcgtgcaat tttatccacg accataaagc cgatattgtg ttttgtatat
    15001 tggtatttgg tacctgggtt tcctaacccg acgatcattt tcatttttgt tttccaccta
    15061 attctaaaaa gcagcacaaa aggctggact gctaattagc ggtccagtcc atcgagcttt
    15121 tttctttttt atacttgtca atgcatagta taacacaaaa caaggcgttt cggctaaaag
    15181 agaatcgtta ataaatgata aagaaattaa aaatttcttc aaagtttaat gaaataattg
    15241 atatataaaa atagtgaaat aacgcacatg taagctttta catataatac aaccttgtta
    15301 tctgttatat tttatagcca aatagcgtga catggggctt gagaaatgtt agcataagca
    15361 tgggaaaaaa caaatcaatg gaaggattga tactaaatga ctgcagctgc agaaaaaaaa
    15421 gatcatcaaa aagttattct tgttggagac ggcgccgtag gttctagcta tgcctttgct
    15481 ctagttactc aaaatatcgc tcaagaagta ggtattgtgg atatcaatac tgctaaaact
    15541 gaaggagacg caattgactt gtctcacgct ttggcattta cttcacctaa aaaaatctat
    15601 tctgctactt acgcagacgc acatgatgct gacttagttg ttattacagc tggcgcacca
    15661 caaaaaccag gtgaaactcg tttagactta gtaaacaaaa acctaaaaat caaccgcgat
    15721 gttgtcacac aaatcgttga atcaggattt aacggtatct ttttagttgc cgctaaccca
    15781 gtagatattt tgacttactc aacttggaaa ttctcaggtt tccctaaaga acgcgtaatc
    15841 ggttcaggta cctctcttga ctcagctcgt ttccgtcaag cacttgcgga attagttgac
    15901 gttgatgcac gtaacgtcca tgcttacatc ttaggtgaac acggagattc agaattccca
    15961 gtttggtcac atgcaaatgt tgccggcttg caaatctatg aatgggtaaa aaacaaccca
    16021 gaaatcgatg aagaagctat ggttaaccta ttctttggcg tacgtgacgc tgcttacaca
    16081 attatcgaga aaaaaggcgc tactttctat ggtatcgcag tagcattagc acgtatcact
    16141 cgtgccatct tagatgatga aaatgctgtt cttcctttat cagtattcat gaatggcgaa
    16201 tatggattga acgacatcta cattggtgca cctgctgtta tcaaccgtca aggtatccaa
    16261 aaagtaatcg aaattccttt aagtgacagc gagcaagacc gtatggctgc ttctgctaag
    16321 caattaaaag aaattctaga tgaagctttt gctaaactag acgctgaata atctttgaac
    16381 atgacggaaa acatctattc ggtgttttcc gtttttttat tttatcaccc ttatggtttc
    16441 taaatttttt cataaagtag agataacctt cgtcttttcc tctaaattat gctatcatga
    16501 gaccgttcca ccctaaactt ttacttaagg agttgtcgat atgacaagat cttcgcatcg
    16561 aaaaaaatcg aaacatgttg ctttgctttc agttcttggt gttctcttag tgctgatcag
    16621 cttttatacc tatcgcagta catactacac aaagcatttt ttgccgaata cagaaataaa
    16681 tggaataaat gtcagcaatc taacagtcga aaaagcaaat gaaaaattaa aagaagctta
    16741 ttctgataaa aaactggcta ttaaagaaga tggaaaagtc tggcaggaag taccaaaatc
    16801 cgagctcggc tacaaagatg atttcacttc ggagctttct ccgatcctaa atgaacaaaa
    16861 cggatggact tggggaatga cttatgtctc agcggcagaa aaacaagaaa tagatcctgt
    16921 cagtcaaaac caccaaaaac tagacactac cgttcagaca ttgacaacta agctgactga
    16981 tttgaacaaa gaccggacac ctactactga tgcaacgatc gaaaaagcag gtgactcttt
    17041 cgttatcaag cctgaagtca atggaaatac gatcgacgtc gatgctgcgg tcaaacaatt
    17101 aaaaagtgcg gtaaactctg gtaaagatac aattgaattg actgaattca aagaaaaacc
    17161 aaaagtaaca tctgaagaca gctcactgaa agaacaactc gcatccatga atgctatcgc
    17221 aaatgtaaaa gctacttaca gtataaacgg tgagactttc cagatcccat caagtgatat
    17281 tatgagttgg ctgacctaca atgatggaaa agtcgattta gatacagaac aagtacgtca
    17341 atatgtaaca gatttaggca caaagtataa cacaagtacg aatgacacaa aatttaaaag
    17401 tacaaaaaga ggagaagtta cggtcccagt tggcacttac agttggacga tccaaacaga
    17461 cagtgagaca gaagcattga aaaaagcgat tctggcaggc caagatttta ctcgttcacc
    17521 cattgtgcaa ggtggcacaa ccgctgatca tccattgatc gaagatacgt atatcgaagt
    17581 tgatctggag aaccagcata tgtggtatta caaagacgga aaagtggccc ttgaaacaga
    17641 tatcgtttcc ggaaagccaa ctacacctac acctgctgga gtcttctatg tttggaataa
    17701 agaagaagat gcaactttaa aaggaacaaa tgacgatgga acaccttacg agagtccggt
    17761 aaactactgg atgccgattg actggacagg tgttggtatc cacgattcag actggcaacc
    17821 tgaatacggt ggagacttat ggaaaacccg cggttcacac ggctgcatca acaccccacc
    17881 aagtgtaatg aaggaattat tcgggatggt cgaaaaagga acgcctgtat tggtcttcta
    17941 acaaaaataa tatataaaaa gaaagcaccc gtacgattgg tacaggtgct ttctttttat
    18001 tatctaacaa tgtgctactt acatttcagc agcagtaaag acttctgaaa catcatcatc
    18061 gtcttctagc ttatctacta gacgttccaa ttgctctttt tgttcctcat ttaaatcaat
    18121 cgtcgtttgt ggaatcatcg tcaattctgc ttgcgccaaa gtgaactctt tttccaactc
    18181 atctcgtaca gcagcaaaat cttctggtgc agtataaatc tcgaatactt caggagaagt
    18241 ttgcagatct tctgcccccg cctctaatac atcctcaaac atcgtctctt catcaacagt
    18301 caacccatcg cgttcaatag cgatatatcc tttgcggtca aacaagtaac tgactgaacc
    18361 cgtttctccc agtgatccac cgtttcgagt aaaagctact cggacatttg tcgctgtccg
    18421 attacggtta tctgtcaatg catggactaa gattcctact ccacccggac catatccttc
    18481 atacgtgatt tcatcgtaat tcgtttcatc tacggcactc gtagcctttt taatcgcccg
    18541 ttccacattg tcgttaggca tatttgcagc ttttgctttg tccacaacaa gccgcaaagc
    18601 tggattcata gatggatcag gaccgcctgc tttagctgcc atataaattt cacgagaaag
    18661 tttctgaaag actttccctc gttttgcatc ttgggcattt tttcttcctt ggatattatg
    18721 ccatttacta tgtcctgaca tgatttttcc tcccttgttc ttttgagaat acacttctat
    18781 tctagtacta tttcacaaaa aaacaaagcc acagccaatc tataaacgct tcttgaatgc
    18841 cgcaaaaagc acacataata tcacagcagt cagagcaccg atcgaatcca acatgacatc
    18901 ttggaacata ggtgttcgtc caccggtcat catctgatgg aattcgtcca aacctgcgta
    18961 ccctgttgct gaaagccaag caaggatcgc tgtcagccac caaattttta gcttggggaa
    19021 aacacctaaa aacaagctgc ctcccaaaat aaaataggta ccgaaatgtg cgcccttcct
    19081 taaaaagaac tctaaaaatt tggcgtagcc cagatggtcg atactcacca tacttccacc
    19141 ataattaaaa cgtatacccg ctaatgtgtc tttaaatggc tgattaggca gccagctttc
    19201 taatcgcgaa acttgtgatt gctgtccgta agtttgagaa gaactgtaaa ataagattat
    19261 aacgactatc agtgcgatta ctaaataaat atttccgttt ttcatttgtt tttttgaaga
    19321 attcataagt cacctctgta ttttatctta gacttttttt gaagaaacaa caatcatttt
    19381 catagagact tcttccataa aaaagtgcta tacttaattt tgtattacaa tatgaaggga
    19441 gttttttcat gagttattca ttaaattgga atctagattc tattttttcc ggaggcagtc
    19501 attctgatgc tttgaaccaa cggatgaagc aattggaaga ccaaatgaac gagtattatc
    19561 accgcgtaac aaaatggtca cctagttctg acaatgcaga gcagttaaac gctattcttc
    19621 aattgcaaga aacgattacg aatggtttta cccaatgcag cagctatatt actgcattgc
    19681 tttctgccaa tgtcaatgat tcagatgcaa aggtcttatc aggcaagctt tacgcaatgc
    19741 tgcctcgtct gcaatcagcc gaaactgtat tgtcaaagaa atttgcagaa atatctgaca
    19801 atgattggaa tcagatgctt tctcaatctt cgtttgaaac aattgctttt cgtttaaacg
    19861 agattcgtcg tgatggctca caattattat cagaagctga agaaaacatt ataaatacgc
    19921 tttctttaga tggtctaaat gcttggagca gtcattatga tacgattgta gccagcattt
    19981 cgattccctt cgaacaagat ggacaagtag tcgaattatc tgctggacaa gccttcaata
    20041 agatgatggg cgatccagat ccaaaagtca gagaaacact tttcgcagca tgggaagaag
    20101 cctggaaaga aaaggcaccc ctcttcacgg atactttgaa tcatttagat ggttttagac
    20161 tttctgacta tgaacttcat ggtgtcacag attttctaca aaaaccatta gagtacaatc
    20221 ggttgaagaa agaaacattg tctgtcatgt gggatacaat ccagaaaaac aaacaacccc
    20281 ttgttaatta cttgactaga aaagctaatc ttttcggtaa agaaaaaatg gaatggcaag
    20341 atcaagatgc acctattatt ttaggcgatt tgaaagaaaa aacctttagt tttgacgaag
    20401 cagcagcatt tattatcgaa aactttaaca aattcagtcc aaaaatggct aaatttgccc
    20461 aatctgcttt tgaaaagagc tggatcgaag cagaagatcg tcctgggaaa cgtcctggtg
    20521 gttattgtac tgagttacca gaaacaaaag aatcaaggat ctttatgacc tacagtaatt
    20581 ctgttaatga ggttgcgaca cttgctcatg aactaggaca tgctttccat agcagcacga
    20641 tgtgggattt accttcttta aatcgcgaat atgccatgaa tgtcgcagaa acagcaagta
    20701 cattcgcaga actgatcgta gccgatgcta cattaaaagt cgcaaaaaca aaagaagaaa
    20761 aaatcaattt gctagataca aaactgcaaa atgctttagc tatgttcatg aatatccatt
    20821 cccgattcat ttttgaaaat cgattctatg aagcacggca agaaggatta gtctcagaag
    20881 ataagatcac agagatgatg gttgaggcgc aaaaagaagg ctatcaagga gctttagcta
    20941 cttaccatcc atatttctgg gctgcaaaat tgcatttctt tattgatgac gtaccgtttt
    21001 ataacttccc atacacattt ggctacctct ttagtttggg catctatgct tacgccaacc
    21061 aaaagggagc aaattttgaa gaagaatata tccatttact acgcgatact gcctcaatga
    21121 cgacggaaga tcttgcgaag aaacatttga atgtcgatct tacccaacca gatttttggc
    21181 aagcaggtat cgacatggtg actgaagata tccaaacgtt catggaattg acagaagaat
    21241 ttatctgatt tctattttat cacaataaaa aaagagttag tccagaatgg gctaactctt
    21301 tttgattaat cattcttaca tgctgacagc aaagtcaggg gcaaaccatt gaactgaacc
    21361 aacttttacg ctttcgcctg gttgaggagc atggatatat tgtcctccgc ctaaagcaat
    21421 cgctacgtgg taagttccgc cttgtgaccc ccagaataac aagtctccag cttttgcttg
    21481 agaaactgaa atttttgttc cagctgattc ttgaggaact gtccaaccac cgatgtcacg
    21541 accagttact tgcatgtaaa catagcgtgt gaaccctgag cagtcaaagc cacttggatc
    21601 tttaccgccc caaacatatg gagtaccaat atatttgtaa gcttctgcta cgattgctgc
    21661 accattcaca cttccagaag gagctggagc aggtgttaca ggttttggtt gttcaggtgt
    21721 tggtgttggc gttggagccg gagtactact tcctgtgccg tttcctgtat caacactttg
    21781 atctgttgat ggtgttgtag gcgcaggtgt tgttgattct tctgttgttg aagattcagg
    21841 cactgttgtt gattcttctg ttgctgaaga ttcaggcact gttgttgatt cttctgttgc
    21901 tgaagattca ggcgctgttg ttgattcttc tgttgctgaa gattcaggcg ctgttgattc
    21961 ttctgttgaa gattcaggtg ttgttgattc ttctgttgct gaagattgtg tagctgatga
    22021 tgattcttca gtcattgaag attgtgtagc tgatgattct tctgttgctg agctttgtgc
    22081 agtagatgaa gcttgagtag cttgtgcttc agcctctgct tgttcgcgtg cttctttttc
    22141 agctttttct tgtgcagctt gttgacgagc ttgttctgct agacgttgtt gttcacgaat
    22201 acgagcttgc tctgcttcag cttctgcttt ttgacggttc aagtcagctt tcttgtcttc
    22261 agcagttgct tgttcagcag ctaatgaagt tttcagtacg ttcaaatcag cttgtttaga
    22321 taaaagatcg cctttttgag attccaaagc agcttggttt tcagctaatt cttttagttt
    22381 agcatcgttt tcagcttttt tgtcttctac agctttttta tcttgttttt gttgttccat
    22441 caagtcgttg tttgctttta ccatcgttgt cattgcttga acgcgtccaa tagcatctgc
    22501 taatgaatca gcattcaata cagcatcgat gtagtttgag cttgtgttgc ttacttgtgc
    22561 ttcgcgtgct tgtttttgga ttgtatcttc acgtttttca atacgttctt gtaaatctgc
    22621 aatgtctttt actaattgtg cagattcttg acgcaatgta tcctgttttg ctaataggtc
    22681 ttgtgcttgt gtgttgattt cagaaacttg gctttctaag gcatcgattt gtgattgtgc
    22741 atctgcttgt tgatttttca agtctgcaat cttttgatct tgctgttgta tctgagaatc
    22801 aaaatcgtcc gccgcggcag cgatcggtga tgctacggca gtcaaggtca ttgaacatac
    22861 cattactgct gatattaaac tctttttcac tcttcattcc tccgactggc ttaatttaat
    22921 aaatatctaa atatatttaa gtctttctta acgatataaa aattgtacca tagcagtgtg
    22981 tcaacgatat aatagttatg ttacaaaaat gtttcaaaac aacttttaaa aatgacaaaa
    23041 ctgttcgttt cagaaaatga tcatgaaaaa gccgcgttaa gtctagcatt tcttaagata
    23101 acaacgattc tttttcgctt tcgacctaaa aataaaaaaa gaaattattc atcactgaat
    23161 aatttcttaa agggaaaaat gaataataca aatataatca tgttcaacag cagtgtaggt
    23221 cctaaaaacc ttgtaataaa atacgtgtta tttactactg ctaatttaaa aatcaactgg
    23281 accaccatcg taaacaattc ataacccgtg acaaagatga tcatactgaa aaattcagta
    23341 aagatgttga catggataac gtctttcatt acatacatca accatacaat taaagggaga
    23401 gctactgcat agataccgat aacgccaata tagtaagcgt catagatagc cccgagaaca
    23461 atcgtggtaa tcagtaaata acgtttttca aacgccatac tgcaacataa taatgccaat
    23521 atcagaaagt gggcatttga catataggtg cctttcgacc actcccctag cattcttgtt
    23581 aaatgaccat ctatcaacat caaaaagaac aaaacgattg gcagatagta cttcattgtt
    23641 tctttcttca acatggacta atcctccgct agccgttgga caatcgtcac aactgacacg
    23701 tcatacattt ctgcataagg tttcacataa acttcccgat ccagcccata actatctggt
    23761 ttcgttttaa taaccgtacc gatcggcaag ttagctggag aattccctcc aagaccggat
    23821 gtctggacaa catccccttc tttgatatcc gtatcaccag ttaattgggt caccactaag
    23881 gcatggagct tttcatcata gtttttaagc aaaccaaacg cttcgccatt agccgaagat
    23941 acccgtactg gaaaatgatt ggagctttca ttagaggatg acagtaattc gattttagac
    24001 gaagccgtat tgacctcgat cactcggcca atcaatcctt tttgcgacat gactgccata
    24061 tttgcttcga taccgtcttt agaacccttg tctacgatca gcatgtcctg ccaactgtca
    24121 ggcgaacgag taatgacatt tgccgttact ttttcgtaac tagtcagcgt ctgattcaac
    24181 tcaagttctt ttttcaacgc ttcgatttct ctctcgtaat tcttgttttg ctgtgaaacg
    24241 tcatcatagc tatcgatttt ttcttttagc cgctcatttt cggcataagt tgaaaaaaga
    24301 ttatggacag aatctactcc atttcgtacc caccgtactg gggcagagat tgttttatca
    24361 accattgcaa cactgtcatt aacgatggat tggaagaaat tgggctttcc ttcattcgct
    24421 cgctgcgcag cggtcacact tagtatcgtc accacgatga taacaataac caaggtaata
    24481 ataatatttt tattaggatt gaacttcttc acaaagacac ctcgaattaa ttagactctt
    24541 gtgttcaatt ttatcactaa atgccgtgaa acaaaaggta agttgctcct cttaagcttt
    24601 tttttagcaa ataatagatt ctgtcatttt tagcctgaaa gacaaatttt tttatttgtt
    24661 tatggatcaa tctttgcttt gaataactgc aatcatacca tctgaaaaag aaaattctgc
    24721 ggtatctgaa agaaattcgt tacttgcata agatgtcgga tattctactt ctttattttc
    24781 caatacatac ttgctgcctt ttaatgtaag attcgagacg ggagtcaagc agcaataagc
    24841 taaatacttc atatctggta tctgtcttac tatatgctct ccaggcaaat aataagacaa
    24901 ataattttga caatctctga taataagctg atgggcaaag ggtttgaagc gaggttccat
    24961 acctaaccag agattggcta aaagatgatc caatcttccg cccgtagctc caatcaaagt
    25021 gacttccgct tgcgggtaac gttcaaatgt ttttaagata cctaactgtg tatctgtatc
    25081 gtctttttct gcaggggaac gggtatactc tttggctttt gcaaatactt ccttctgctc
    25141 ttcgttcgac aatgaatcaa aatcacccac tgccagatct actgggtagc ctgcttgaag
    25201 caggtacagc gcaccacggt ctatcccgac ataggcatcg tatttggaca gcagagactg
    25261 cggccagttt tgcggattac ctccagcagc taataaaatt ttcatttagt ctaatgcctc
    25321 ttttaatcgt tcgatttgtc cgactggatt ttcggctcca tagatatatg atcctgcaac
    25381 gaagacatcc gcccctgcat ctttacagat ttttgctgtt tctggaacga ttccgccatc
    25441 tacttcgatt gcataagtcc aattgttctc tctacgtaga tcagcgagtt ccgtaatttt
    25501 ttctactgtt tcttcaataa agctttgtcc gccgaaccca ggattgacag tcatgactag
    25561 tacttgatca gccaaaggca aaacatgttt gatcatggag actggtgttc ctggattgat
    25621 aactactcca gctttaactc ctaagctttt tgtcatttga agtgcccgat gaatatgagg
    25681 agttgcttcg acgtggacag taatgatatc tgctccagct tttgcaaatg ctggaatgta
    25741 gttttctgga tcaacgatca tcagatggac gtctaacggt aatttagtaa caggacggat
    25801 tgcctgaaca atatttggcc ctaatgtgat atttgggaca aattggccat ccattacatc
    25861 tacgtggatg taatctgcgc ctcctttttc cactaactca atgtctcttt gtaaattggc
    25921 aaaatctgca ctcaaaatgg atggtgctat cttcattctt gtttcctcct attttcgttt
    25981 accttctttt tttgcataca ttggttttct tttttcgatt tcttgtaaga attgcaaata
    26041 attgtcgtaa cgtgtctgtg cgataccacc tgtttctact ctatgtttta cttcgcagcc
    26101 aggttcttta gcatgcatgc actctctaaa tttgcaatgg acagaagctt ctacaaattc
    26161 aggaaattgt ctcggcagtt ctcctgcttc aattgtcaaa aagtcaatcg agctaaatcc
    26221 tggtgtatct gctactaacc cgccatagat aggaatcagt tccacatgac gtgttgtatg
    26281 ccgtcctctt ccaagtgcat cagaaatctc tcctgttgct aaattcagtt ccggtgatat
    26341 ttgattcagt agcgtcgatt ttcctgctcc agactgaccc ataaagaccg atagccgttc
    26401 tgggaagtaa cggatcagtt ctgtcgtatc acccgtatga ttgggtacaa tcaccggata
    26461 gcctatttta gtataggttt gcttgatctc ttcgattttt tctgggtcgt ctgacaagtc
    26521 ggtctttgtc aaaaaaataa tcggttcgat cgactcgtat tccaaggtaa ctagaaagcg
    26581 gtcaagtaga ttataagaaa atgcaggctc tacgatactt gtgacaatga ttccaagatc
    26641 aacatttgtg actggtgggc gaactaattg attttttctc ggcaagattt ccagaagata
    26701 gccgtctgtt tgattttcac tctcaaagat cacctgatct ccgacaagcg gcgtgatttt
    26761 ccgattccgg aaatttcctc ttcctcttgt ttgataggtc tctccgtttg cgtatacata
    26821 gtaaaaaccg ctgattgctt ttctgatttg tcctttgata agtgccacct ccgtttttgt
    26881 ttattttacc atacgaagag gaaagtaggt gttattccat gcaaacttct caaagtatat
    26941 ggcttgaaaa ttgatcaaaa gagatagaaa cacaaaaaag agaatgcaac aaatcaatgt
    27001 cgcattccct tctgatatat tttattcagc acttattttg aactttctga ggtgctagct
    27061 gatgaacttg tggagctgga agattcttct tttgaagagt tgcttgtgct actggagcta
    27121 cttgagctgc tagaactgtc tgaagagtct ttttcagaac tagaagacgc tggatctggt
    27181 cctttagagt aaattacgtt cacaaccatt cctttggtaa ttgtcgttcc tgcccctggt
    27241 actgtacgaa tcactttatc tttatccacc gtgtttgaat attcggaagt ctcatgcccg
    27301 atatattctg caccgacact agctaaataa ctttgtgctt cgctttttgt atagccggag
    27361 atatcattca atttaggctc tgttccttgg cttacgacaa aattgatgta agtttcttct
    27421 gctacaactt cacccgaggc tggatcctga ctgatgatcg aacctgatgg tacagtgtcg
    27481 ctatagtcat aagtagcact aatattattg atattgaatc cttgtgtaac aagccaatta
    27541 cgaacagttt cgtagttttc tcctacatga ctactcaaag tcactgtttc tggtcctttg
    27601 ctgactgtga aagtaatcgt gtctgtttta ggatcgactt ctgtatcttc tgatggagat
    27661 tgcgaaatga tcattccgct ttctacctct gaactgaatt cctcttcttt ttgaatcaag
    27721 tcagcagaaa accctaattc tttcaaactt gcttcggcat cttcataact tttaccactg
    27781 taatcatcta atttgatttt tttcgtgccg ctactaatat acagagtgac ttcgcgtttt
    27841 tgcttgactg tcgttcccgc tgccgggtct gtcttcacta cattaccttc ttcgattttg
    27901 tcatctgcaa tttcttctgt ttttgttgct acttctaatt tcgcttttgc gagtgtttct
    27961 ctagcagaag cttcagaaag atcagaaaca tcaggaacaa caacttctcc tcgcccgcca
    28021 gaagcaaaga atacagctgt tccgattcct aaaacagcaa gaatagctaa taggatcagc
    28081 caccattttt tctgtccttt ctttttagga tcaggcagaa cttcttcctc ctctggtaag
    28141 gtttcgtttt ctggcttgtc ttttggcaga ggcatagatt tgaatgaatc aggcattggt
    28201 gcatcttccg taaggggtgt gataactttt gtttcattat ccatcacatg aggctgccat
    28261 ttttcttcgt ttgcacgagc tggtgataat actgtagaaa gatcatcaga catttcctcg
    28321 gctgacttat aacggtctgc aggttcttta gccgttgccc gtaaaatcac gttttccagt
    28381 gcttgtggca catttggatc aagtgctttt atagatggaa gatcatcttg aaaatgtttt
    28441 aaagcaattg ttacagcaga ttcaccatca aacggtacgc tacccgtcaa catctcataa
    28501 aggatgatcc ctaaagcata aatatctgac tgcttcgttg ccatacttcc tctggcctgc
    28561 tcaggggaca gataatgaac agatcctagc atcgtattcg tctgcgtgat cgatgtttca
    28621 gataaagcga tagcaatccc gaaatccgtg atttttacaa caccttcatt atcgatcagt
    28681 acgttttggg gtttcaaatc tcggtggatg atttgatggt tatgagctaa agaaatagca
    28741 gaaaggatct gctgcataat atttactgct gtttcataag gaacaggata atgtgtttgg
    28801 atatatcgtt tcaagtccat tcctttgacg tattccatca ccagatactg catgttgtct
    28861 tcttcaccaa catcgtaaac actaacaatg tttggatgaa cgagttctgt tgctgctaaa
    28921 gcttctctct gaaatcgtcg aatcgcagtc tggtcatttt gaaagtcaaa tcgtaagact
    28981 ttaactgcta catcacgatc caagattaaa tcgtgcgcca aaaatacatt tgccatacca
    29041 ccgctaccga tatttccagt gatttgataa cggccattta attttttgcc caactcgatc
    29101 atacactgtc ctccttatat tcgataagaa gaacggtgat attatccgct ccgcctgctt
    29161 cattggcacg atcaatcagc tcagttactt tatgagacaa tgggccttct tgattgatga
    29221 tcgttcctat ttcttcttca gacagcatgt tcgtcaagcc atctgaacat aacagcagtc
    29281 gatcttttag ttgccaaaga tgagtagaaa catctacttc gactgttcca ggcatgccga
    29341 cagaacgtgt taaaatattt ttccttggat ggttcactgc catttcttcg ctgatttctc
    29401 ctgatttgac tagttcattg actaaagaat gatcctccgt caattgcatg attttatctt
    29461 cacgaatcaa ataagctctg ctatccccaa cattggcaat cgtgaaccag tcatctgaca
    29521 gagcggccgc tacgattgtt gttcccatac cgttatattc cggctgttct tgtccacgct
    29581 gataaatcag catattttct tcttgaatcg attgaatgaa ccattgggcg attttttcat
    29641 cgtcaacagc ttcttgtttt tcccaagctt cgcctagatt cgttaccgcc atctgactgg
    29701 caatgtctcc ggcacgatga ccacccatcc cgtctgctaa tacagcaagc ttgagacctg
    29761 aacggctggt aaatacactg gcatagtctt gatttgtgtt acgtcgtctt cctacatctg
    29821 attgatattc aatctgcatt ttttcacctc attacttttt gcgcaaacaa caaatgaaaa
    29881 atccatctgt gtaaaactga tgcggataca aagtcaacat tttctcttcg attgatgatt
    29941 gtagcatagg attggtcaaa acatcaatcc tctcaaaatc agggtgtctt tccaagaaag
    30001 cagaaacaac gtcttggttt tcttctttta agatcgtaca agtgctataa gtcagaatac
    30061 cggaagactt taaagttggt gcgcagcttt ctaaaatttc caattggatt tttggtaaat
    30121 tcgctaattc atccggctgt tttttataac gaatatctgg ttttcgccga agcagcccaa
    30181 gacctgaaca aggcgcgtct actaaaatcc gatcaaactg ctctgcttcg aactgtttac
    30241 tgacttctct agcatccatc ttttgagcgt agacagcaga agagacacct agacgtgctg
    30301 cattatcttc aatgagtttg actttgtgtt cgtgtacatc taaagcgacc acttctccac
    30361 cgcatgacgg atctaaaaaa gaagcaatat gcgtcgtctt acctccgggt gctgcacagg
    30421 catctaagac atgatgttca ggctcgattt gcatagacgg cgctacaagc atcgaacttt
    30481 catcttggat cgtcatgacg ccatcgtgga acaatgagct agaagctaaa tgcccttttt
    30541 tcgctactat accgtatgga ctgacttggc ttttttcagc tgtgatctct tcttcttgca
    30601 aaacagtgat ggcctgatct ctggaaagtc ggcgtgtatc tactcgggca ctagcatggc
    30661 taggctgata tagcgataaa ccgagctttt cagtttcttc gtatccgatt tgatccacca
    30721 gtcgtttagt catccataga ggcaggctga ttttgacaga aagtctttcg ataggatcag
    30781 caatgccttg cagatctggt gctccttgac gctgataatt cctcaagaca ccatttacaa
    30841 atttccctgt cccaggattt ccttttactt ttgcgatttc gaccgcctcg tttaaaatag
    30901 catgtgcagg gactttatct aaaaattcta attggtatac agaaagataa agaagcgtct
    30961 tgacccagtc atccactttt tttgctttag cgatcaatgg tgcaacgtaa aattccaata
    31021 gtcgctgatg gctaatcgta ccatagatca attctgtaaa taaacccaca tctttttgat
    31081 ttagctcgct ttgtttgatc atctcattca acaaaagatt cgagtaggcg ccacccttgt
    31141 tcactcgctc taatgtcagt aatgccatat atcgtactga ttttttcatt tttttaggga
    31201 tttttttcat tatttcacct gctgaccaat ctgaacttgc tgaccgcttc cgttaaggaa
    31261 atcatgtacg gcctgttttc ctttaccagc tggctgtaat tcattgatgg ctaagacggt
    31321 ctgtttaccg caagcaatcc atagattttt tttgtctttc cggatgatcg taccaggtgc
    31381 tttgtctgta gtttctgcca atacttcaac cgataataat ttccagcgta tgccctcata
    31441 ggtcgtgaat gcaattggcc aaggacgcat tccgcgtact tggttgtcaa tttcttctgc
    31501 agttttatgc caatcgattg cttcttgttc ccgtgtgatg tttggcgaaa aagttgcttc
    31561 tgactcgtct tgaggtactg gtttttgtcc atccaaaata ttgggcaatg tttctagcaa
    31621 tagctttctt cctaaaaggc taagcttttc aaacatcgtc cctacatcat cttgtttagt
    31681 gattggtatg ctttcttgcg catagattcc gcctgcatcc atttttttga tcatttccat
    31741 gatcgttaca ccagtttctt tctccccatt catgatggca taatgaacag gcgcacctcc
    31801 ccgatattta ggaagtaaag aagcatggac attgattgcc cctaattttg gtacttgcaa
    31861 taacttttca ggcaagaatt ggccaaatgc cgcagtgacg atcacatcag gcaccaattc
    31921 aatgatttct tccatttctg gcgaaccgga gattttctct ggctgcagca cacggatacc
    31981 gtgcttcaga gccgcttctt ttaccggtgt cggcgtaatt actcgtttcc gcccaactgg
    32041 acggtcgggc tgtgttacca ctgcctggat ctcgtaacct gattctatca gcccttcaag
    32101 aatcggcaca gaaaaagcag gtgtgcccat aaatactagc ttagtcatca agatgttcct
    32161 ccatatattc ttcaagttct tcttccggga tctgctgtat cattttctca atgaacaaga
    32221 taccgtctaa gtgatcgatt tcatgctgga aggcacgggc taaatagcca aaagccgtca
    32281 cttctatctc ttctccgtct cgatcataat aacgcacggt cacttcatct gctcgcttga
    32341 ccgttccata gacatgcgga atactgagac aaccttctac gtcaaggctt tcaccttttg
    32401 cttcgatgat ttctgggtta atcagttcaa atttctcgcc ttcatctact tcgatcacag
    32461 caattctctt gttttgtcct acttgaggag cagcgatccc tattccgtca ttcgcaatca
    32521 ttgtctcata taaattgtct aataaagcga ttgtctcgtc cgtgattaca tcgattggct
    32581 gagcagttct ttttaattta tcattagggt ggatcaatat aggatagcgc ataatttggc
    32641 cctttcttaa ataaagttta atggttcgtt gtcaattgcc acaaaaagac cttgtcgctg
    32701 ttctttctgg cttccattca aaatttcatc caaaacatga ggaagattcg gttcatgttt
    32761 atatttgatg attagttgat aataatatcg gtttttcact ctcaaaatca tgctgggcgt
    32821 tggccctaat agcaagcttt gagggcttaa cacttctttt agctgattgg caatctgaaa
    32881 gattttcttt gccgctactt gttcttcagg atggctggcg gttattttca cagtaaagta
    32941 ataaggagga tagcctccac gatgccgtac atgcatttcc tgctgataaa actgctcata
    33001 attttgtttt ttagccaatt ctatggcgta atgttgagga ttgaatgttt ggatcacgac
    33061 ttcgcctgct ttttccgctc gccctgctcg tcctgaaact tgggtaagca attggaatgt
    33121 atgctcacta gaacgaaaat ccggtaaatt cagggaggta tcagcattca acaccccaac
    33181 taatgtcact tctggaaagt ccaaaccttt agcaatcatt tgtgtcccta ataatatatc
    33241 tgcttctttt gcaccgaatt tttgtaaaat ctgttcgtgt gccccttttc ttcgagtggt
    33301 atctacatcc atacgcaaaa tcctagcttg cggataaagt tctcggagtt cctcttctac
    33361 tttttgagta cctgttccat agtagcggat tttattgccg ccacaattag gacagcgatt
    33421 gggaataggt tcttcatgtc cgcaataatg gcagcgcatt gaacgtgtat ccatatgcag
    33481 tgtaagagag atatcgcaat taggacatgg aagaacaaat ccacagtccc tacacatcac
    33541 aaaagacgaa tatcctcgac gattgagcag taggacagtt tgttcttttt tgtctaatcg
    33601 attttgtatt ttttcctgca aattagcaga aaaagtagag gtccgatgat tctgaaactc
    33661 ttcacgcata tctacgatct caatagctgg aagctgtgca gctgctttgg ctcggtggtt
    33721 taactgcaat aactgataaa cgcctttttg agctcgtgct cttgattcta aagagggcgt
    33781 cgcgcttcct agaactattg ggcaatgatg atatttactg cgccaaattg ctagatctct
    33841 cgcatgataa cgcggtgtct catcttgttt gtaacttgat tcatgttctt catcgataat
    33901 gatcagcccg atatttttca gcggggcaaa aatagcagat cgtgcgccta ctactacttg
    33961 cgcttcttcc cgctcaatct tgcgccattc atcatatttt tcaccttggg aaagtccgct
    34021 atgtaagacc gcaactgatt ctccgaagcg tcctttgaat cgctcgacca tttgcggagt
    34081 caatgcgatt tcaggcacta acataatagc cgttttattt tctgacaaaa catcagcgat
    34141 tgcctgaaga tatacttctg ttttcccgct gccagtgatt ccctccagca aaaagacctg
    34201 atctttttgc tgctgacctg ctgtgatgat ttgttcgaca gcattttttt gttctgcatt
    34261 cagttccaat gccgtcgttt ggtcaaatac tcggtcttta taagggtcgc gataacgttc
    34321 tgattctata aactccagcc agcccttttc ttttccttga ttcaagacag cagtactgat
    34381 tcctttattt ttgaaataag caattggttc ttcttggctc agttcagata aacacaaaag
    34441 aagttctttt tgtttcttgg cattttgccg taattttgcc cattcttctt cgatttgctt
    34501 ttcagttaac aaagaacgga ccaaacgaat cgtttttact ttatttcgtg tatggacttc
    34561 atatttgata tctactaatt gctcttggcg ccagcgaatc aattgagaaa ggctgccttc
    34621 ttcttctgct tccttccagg aaatcacttc tcgctgatca aacaatacct gaacttctgg
    34681 tgtgtctgcc aaaggataga tcaatttatc atattctgct ttcatcacac tcggaagcat
    34741 cgtttgtaga caagtgattt tgaatgcgta agtaattttt ttcatataat cagctaatga
    34801 aagtaattct tcattgacca ccggagcaag gtctagcaaa cgaataactg ccttcaaaga
    34861 tggattagct gattcttctg atttttggat agccataaca aatccttgga catgacgatt
    34921 gccattacca aaagggactt ctactcgcat cccgacttgc aaagctgttt ccatttcaga
    34981 gggaaccaaa taagtgaatg gctgatcggt ctgcatagta ggtacgtcca caatgacttc
    35041 agctgttaat gtcatggttc gtttcctcct ttttttgtct tttcttatca agcgacaaaa
    35101 agttccttgc ctattttact agagatcgat ggatttgtct tatcttctgc caaatcctaa
    35161 caaaaaatta acagcagata agaaaaaaaa gaactgtgtc aaaaagttca gacacagcct
    35221 tttctaccag acaataagtg gcgaatgttt gaaaaggaaa cagctgggtt tgcttttctt
    35281 tttagatgtt cgctctattt ttctttatta cattttttgc tcttcacgga tacgtgattc
    35341 caattcgtgt tgttcacgct ctttttgtgc ttgacgttcc tcttcttcca tcttcaaacg
    35401 ttcacgtttt aattcaggat gtggatcatt gactacattt cctgcatcga tttcttctaa
    35461 agcttgaccg acgcttttta ctgaatcaaa agaatctaga gtaggctgtg cacttgcatc
    35521 caattcatgc gcgcgtttac ttgctaaaat cactagagaa tattttgaat ttacacgatc
    35581 taatagtgag tcaattgaag gttttaacat cataagacta catctccttt aacattttaa
    35641 tatatttacc gattacgcga tctactcgaa aatgttcact ggcaataatg tttttgattc
    35701 gttcaactgc tagcggcact tcatcattta caacagcata gtcgtaaaga gccatcattt
    35761 cgatttcttc ttttgcaact ttcattcgtt cttcgattac ttcatctgca tctgttcctc
    35821 ggcctacgat ccgtgatttt aattccgcta aatctggcgg agtcaaaaag atgaatacac
    35881 catcgggcac tttttctttg acttgttttg ctccttggac ttcaatctcc aagaaaacat
    35941 cttttccttc atccaatgtc ttgttgacat atgacaaagg agttccataa taattcccga
    36001 catattctgc gtattccagc atctctccag cttcgatcat tgattcaaac tcttctttgc
    36061 ttcggaagaa ataatcaacg ccttcgacct ccccttcacg cattttacgg gtagtcattg
    36121 agatcgaata ctgaaaatca ttatcctcac tctcaaaaat tgcttttcgt actgtgcctt
    36181 ttcctacacc ggatggacca gacaacacga ttaataatcc acgctctgac atgacgacgt
    36241 cctttcaact agtctttttg tacttatcgt ttattttgca ctttttttct gcaactttca
    36301 aggttatctt taattatagc tagaaattgg taaaaaagct accctgtacc aagaggtcgt
    36361 aaaaaagctg tcctgcatca agtaataaga acagccaaac ataaacagct tctcatgttt
    36421 ttcgtttggt tggggttatt atcgcagatg caagcttttg aacgccgtgt ataagaggtc
    36481 gtgaagaagc cgattagttt cgagtatgaa gaaaaatttt gtgaaaatag tttctcacat
    36541 ttttgcataa atttggctta ataccgagaa aatggttttt gaacatcact tattcaaaat
    36601 aaaaaaagat tgtgacacga attttgtcac aacctttaaa tgtattccta gagcaaagaa
    36661 gctaagcgaa gaaatccaat tctgattatt tattgtattt ctttgttcag catccttgct
    36721 aaaagcccat attggacaaa gtattcacta cacccatgat ctcatctttt cgagaacgtg
    36781 ctttttctgt cggatcttct acctcttctg tgtcaattcg aacaataaat ttccgattca
    36841 tcgtcacgta agcaccgtcg ttgatcaaaa taaacagttc gttctcatta tagtctgcac
    36901 aggcatcttt ccatacgtca aagccgtttt tttcagaagg gatatcccgt ttaaccacag
    36961 tttttccact taattcgtgg aacgttacgt cataatattt cattatctct acctctttcg
    37021 tcattcaata ttttgtactt gttctctgat tttttctaag atcgtcttag actggacgac
    37081 ttgattttta atttcgattg catttgattt ggaaccgatc gtgttgattt cccgattcat
    37141 ttcttggatc aggaaatcta attcccgacc tacaggacat tgtgcttcga taagttcatc
    37201 tagtttttgt acatggatcg ccagacgatc cagttcctcg tgaatatctc cgcgttccaa
    37261 caagatggct agctccgtca acaaccgttg ctcatcgact ttcgctccaa gaaattcctc
    37321 cagctttttt tgatacctta tttgaaattc cttttcatag atttctacaa aactatcgag
    37381 tttttttagt acttctttga attcttcagt attctttttc aacactaaag ctaaagcttg
    37441 accttctttt tctcgactcg cctcaataga atcaagtgcg cttttcaatg tatctagagc
    37501 taactgtgcc aattcttcca tgctctcttc cggtttttct tctaccgtta cgaagttttc
    37561 gtccagcgcg aagcgttccg ccatccgact aattgacact tgattttgac taccgtatcg
    37621 ttgttgaatt ccgtctgtca attgagtgat aagtgaatca atcaattccc agttgatgac
    37681 gatctgtttt tcgtttttgc caatataagc tagattcaca aatacttcga ttcgaccgcg
    37741 gcttaactgc tgtttaataa gctgacgaaa atcgttttca acaaagttca ggattttagg
    37801 acttcgtatt tgaacatcta gaaaacgctg gttgacactt tttatttcaa tatctaactg
    37861 atacgctttt gtttcgcgga tggctttgcc aaaaccagtc atacttttca ttcgacaggg
    37921 tccttcctca ttacatattt tctattgctt tttgcagttg ttcaaactct tcgttcgtca
    37981 atgtcaggcc tttccccatt ttttcatggt ctggcgccca atctcgaaga tcgaattttg
    38041 gcgggcgacc attccagctg actaggttca gttctttacg ccaccccttg ttgttttctg
    38101 acaatatagc gatttcttct acgatttcat atgaaaattc ttgtgccatg gttgttcctc
    38161 cttgagataa tataaatata ggatcagtaa tgtgtcaact ggttgcttaa gcaattcatg
    38221 ctgcaaacga tccttgcgtt ttccttgtag cagataatca aaataaacag ttttcgtgcg
    38281 ctcattttgt attttttgct ggtattttcg ataccttcgc cattcttcag tacttaattg
    38341 accaatttgt gccaataaat catccggcat actttttata tcttgttggc agatcatttg
    38401 aatcatcatg tctacttgat agatttcatt gggcagtaaa aaatgttttt ttgctaaaag
    38461 ttctagcatc gccaatccgc atgtctctgg tacgaccctg ttcttatata aattacgcag
    38521 tttttgccaa aattttatgc ttttgaaaaa agataattct aactgaattt cttttgttaa
    38581 gtaagacaaa aatcctcgcc agtatgttct tgcaggttta acagaatgaa atgtatacca
    38641 gttcccatag taatagccta atcgtttttt catttccaga tagcctaatt gtaaatttaa
    38701 ttggttcctt tggctatcaa aaagcagaaa gctgcctagt gtccacaatg tttgacattt
    38761 ccaatggata aaaatgtctg gcatacgaat ttttttcgct gggcctggcc cttgcacatc
    38821 tacgacaaat gcctctgttg ctcctttgtt aatcgcaata tcaataggta ttttgttgcg
    38881 atacccaccg tctgcatatt tattttttcc gatctttcga taagccatag cgggataaaa
    38941 tgaagcagag gcgagtatcc aatctggtat ttcttctgtt tttgtctgtt ggatatcagt
    39001 cactacttcc gctagttctg gcagtttagt agacaccgta tataaacgta ttttgggatt
    39061 atgtttgagt aaggacaaat ccaaattgtc tttgaccatc ttttccaatg gagcagaaga
    39121 aaccccgcct tcaattagtg ctgttttcgt catttggcgt ctttctcgat agaagcgttc
    39181 acgaaggtct tcaactgcag ccatttctgg taacgcaagc acttgtcttg tcgacagctt
    39241 tttccataaa ttcacagctt ttttcatatc tccttgtaaa atcaatgcgc cgttcaacgc
    39301 acctaccgag gtacctgtga taatctcaaa gttgatatca tgttccttca gcgcctgcca
    39361 cacaccaatc tgataagcac cgtgtgctcc tcctccacct aaaacaagtg ctgtatgata
    39421 gaccagcttt ttatttaatt gtgtggttcc ttgatagccg tttttatgaa aaatacgcaa
    39481 ccattcttct gatagaggag attgaaataa aaaacaacag ttttctttaa taaaaaaacg
    39541 agcgcaagct tccatatacc gaaaaaattt tttccattca aaagtttcac cttcaatcaa
    39601 cagattatta aaaataacat ctcctctact tttagcaata gtaaaataga cggtatattt
    39661 tttcgatact gctttaaaag cacattgctt ttttgcagaa cgccaaaaag cgtctctact
    39721 ttcttgatga ctttgaaaaa atggaagggg ttgttttgct tgctggatag gcgaatacag
    39781 cgacattttc tgtgaaaagt aaactttttt tatctccatc gcgctctcct ttttcttcaa
    39841 gtataccagt acgtcataaa aaggtcatga gtctcgtatt cgactttgta gattccataa
    39901 gaaaacaatt cataaaacat cctttaaata aaaaatacaa aaatcacaaa aattaattga
    39961 aaatgagagt gttttcaatg aaaacgtgat tttgtaatgg aattttaaaa taaaagaaac
    40021 aagctttttt aatgcaaatg ttgtaaaata aaagagatta agaggaaata agaggaggaa
    40081 catgatgact gagtcagttt atgtacatat tgataccaca agtaatgctg ttttaacaaa
    40141 agggctgact gctactgact ttgcaaacag tatcgtgcat tttcctcaaa acttgctctt
    40201 gcttgatcca tctgcttctg ctggagaata tgaatcccat acagggctga aagtaatccg
    40261 tggtacagaa aatattcagc gtttcttttc ctcttctcgt aacaggcgtg gattcgatga
    40321 attgaagtgg atcgacttta ctgatttaac gatgctgaaa gaattgacac ctttagaaat
    40381 ttcagaatta ttatattttg gtcatatgaa aacacatctt cattcgccgt ttttttataa
    40441 actacagaat aattttgtat acttcgatct taatgatcag ctgaatcgga tttattatcg
    40501 ctatttagat gaattttata ggatttttgc tagtaaatta agttcgatct tgtcagataa
    40561 gatcaatgta aaaaaatctt ttttcaaaaa agaaacacct gttgaaaaaa tcagtgtgga
    40621 attattgaaa gaaatgcgta atttgatgca ggaagggatc attttttctt ttgatcaagt
    40681 tggtttgatc gatggtaaat atcgtatccc aatctatgtg attgaagatt atatttggaa
    40741 attaaaaggc acccggtatc gagaagagga aatcatcgct actttaatct actctgtcac
    40801 cgatcgacac tggcaattgg tagaagatgc cgatctttct tatctgccat tgaagtagat
    40861 ctatttctta tcaaaaaata aaaaggaaac aagaaactag gacatgattc tgtctcaagt
    40921 ttcttgcttc ttttttattt acagctcctg tcgtttatct ggcacaaaaa tcgaaggagt
    40981 cgtttgttgg atccctaata aaacgatgat cgttacaata gctgtactca acccgctggc
    41041 accattcatt acgaaagaaa agagccaaga attcatcccc catagtgcat acgctcccca
    41101 gaaaaccact cctgcaataa aatgccaaaa atatctggaa agtgcgccaa tcaatgcacc
    41161 aaacacgatg ctttttctaa tttgtttcgt attatcgtct acatagcctt tttggacatt
    41221 tgaagccatg agccctgctg cgcctgcaaa agtataggca atcgggtact caatcaacac
    41281 ttgaacgaca cttaaataat aaacttgtcc caacggaaaa tgtaggatgc cccaaatgaa
    41341 acctgccagc atccctgcct ttgtccctct tcttaacgca aaaagagtca atggaatctg
    41401 ccctaatgaa atagaaaaac tgctgccgat ctggatcgga atcaacgaca acaccatcgc
    41461 taacgctgca acaatcgttc cttctaccca aactctattt tttcccataa aaaaacttcc
    41521 tcctttgaat aaaaaagtca caaaggagga agcagctttc gaaaatagtc aaacagctgt
    41581 ttattcacaa ttcctacgct cgcataaccg atacaggtac gaagggttta gaaatagatt
    41641 caatctcagc ccaattggac tcccctttgt gagtttattt attatttatt ttttgtttca
    41701 aacaatggac taactggttt gttttcatgg atacgtttga ttgcatctcc cattagtccg
    41761 ccaacactta cttcatcgat tttgtcgatt ttacgatctt ctggaagata gatcgagtct
    41821 gtaacaacta gacgctcgat agctgaatct tctattcttt gtaaagcagg gccggataat
    41881 actggatgtg tacatgaagc atacacacta gttgcaccag cttctttcaa agcattggca
    41941 gccaatgtga tcgtacctgc tgtatcgatc atatcatcga tcagtacaca agttttgcct
    42001 ttgacttgtc caatgatatt cattacttct gcaacatttg cttttggacg gcgtttgtct
    42061 atgatcgcaa tcggagattt caaaaattcc gctaatttac gtgcccgtgt gacaccacca
    42121 tggtctggtg aaacaacgac aacatcatcg cctttgattc ctttttctaa gaaataattg
    42181 gcaataagtg gcgcacccat caaatgatcg actggaatat caaagaaacc ttggatttgg
    42241 actgcatgaa ggtccaaagt cagcattctt gttgcaccag ctttttgaat catgtttgct
    42301 actaatttcg ctgtgattgg ttcccgtgca cgtgctttac ggtcttgacg cgcatagcca
    42361 taataaggca tgactacgtt gattgttttt gcacttgctc gtttcagtgc gtcaatcatg
    42421 atcagcaact ccatcaagtt atcattgact gggctgctcg ttgattgaat aacatagaca
    42481 tgcgatccac gaatactttc ttcaatgttt acttgaattt ctccatcact aaattgagta
    42541 acagatgatt ttcctaactc gacgccgact gctgctgcaa ttttctctgc taatgggcga
    42601 ttggaattta acgcaaaaat ttttaatctt gggtcaaagt aatgttttga catggggacc
    42661 tccactttct ttttcacaac tctagaattc tacctaataa atagtagtca tattttttaa
    42721 ataaatcaag tgattttgca aaagtcttag tttagataag ggagtttttt tgcatatcct
    42781 tctttattga cttgtcttgc tctcgcaatt gccagcgcat attctggaat attgtctgta
    42841 attgttgacc cggcagcaat cgaactgttt ttagctacct cgacaggtcc gatgatattc
    42901 gtgctagaac caataaagct gtggtcgccg acagtcgtat gatgtttgtt ctttccatca
    42961 tagttgacga agacaacacc acatccgaca ttgatttctt ctcccagcgt agcatcacca
    43021 acataagtca agtgaccgac tttagttcct ttgccgattt gagcattttt cacttccaca
    43081 aagtttccga tatggacgtt ttcgccaatt tcagcttttg gtcgtaaatg tgcataaggt
    43141 cccacatctg catgtttctt gacatggctg ctttcaatga ctgagttttc aatgacgacg
    43201 tgatcctcaa tcctactgtc tacgattttt gaatgtgacc cgatgacaca atcagaacca
    43261 atgactgtat ttccttggat ttgtacacct gcttcgatca atgtgtctgg accgatttct
    43321 acgcctgcat cgatgtatgt cgttgctgaa tcgacaaagc ttacgccatt gaccatatgc
    43381 atctggttaa ttcgctttct catgatctca tttgctttag ctaacgcgat ccgatcattg
    43441 actcccattg attcttcaaa atcatccgtt tgataagcag caactgtatg gccttcttct
    43501 tttaagattt cgatgatatc tgttagatag tattcacctt gagcattgtt tgttccaact
    43561 ttgcttaacg catcgaacaa agcttcgttg tcaaaacagt aagttcctgt attgatttct
    43621 tgtacaagag cttcttctgg tgttgcatct ttttgttcca cgattttttc tacgatccca
    43681 atatggtcac ggatgattcg tccatatcct gttgggtttt ctgcttgtgc cgtcaagatc
    43741 gttgcacttg cattttttcc ttggtgatat tcaaaaagat tgttcagcgt ttcagtagtc
    43801 aataatggtg tatcgccact gataactaac gttgttcctt tttttccttc caagaaagaa
    43861 gcagcttgca aaacagcatg tcctgttccc aattgttctg cttgtaacgc atatttactg
    43921 cgttctccta gttgtgcttt aacttgttct gctccgtgtc caacgatcgt aatcacttca
    43981 tctggtttcg tttcactgac ccgattaatg atatgttcta ccataggttt accagaaacg
    44041 ggatgtaaaa ctttatataa ttttgacttc atgcgggtac ctttccctgc cgccaaaata
    44101 attgcataac gtgcgtccaa ctgcgtcact cctaaatata gtttgctgat ttcagtttat
    44161 cccagtatac ccattttttc aacaaaacaa gtgattttct tttatcccag cgttttctgg
    44221 ataaaaaaat agatagacca taacgggcct atctatttgg taaccggtgc tctcctgcca
    44281 actcctcggt cacaagtcac actactcata aaacatgaaa agctgttttt tgaaatcgtt
    44341 tcttgtgact tagagttaaa cggtaggctt acaacctctt cattaaacgt ttttcaatca
    44401 gctgaccttc ggtattagct caataaacgg caaaatatga ggagcaattt ttccgtttat
    44461 tgagctaata ctcaggacag gacgctgatt tcacaacctc tagataaacg gtgttcaaaa
    44521 gccagtttct cggtattaag ccaaatttat gaaaaaatgt ggaaagccat tttcacaaaa
    44581 tttttcttac tactcgaaac taagcggctt tttcacaacc tcttattctg aaaaataatt
    44641 tcctggcaca accgtaatat ttttcgtttg agtatctaca tctttgacat aaagcagtga
    44701 cgtataatca tcgatggcgc gatgaccgtt gaattttgat tcggcaaata cagtgatgcc
    44761 aacaagttct gattcgaatt cttcaatcaa gctcttcatt ccgttgactg ttccgccgcc
    44821 tttcatgaaa tcatccacta caaggacacg tgaaccacgt ttcaaacttc tcttagacag
    44881 ttccatcttt tcaattcttt cagaagatcc agacacatag ttgacactta ctgttgatcc
    44941 ttctgttatt tttgagtccc ggcgtacaat aacgaatggc gcattcagat aataggacac
    45001 agcttgggca ataggtacgc cttttgtggc tacagtcatt acagcatcga ttttttcacc
    45061 aaggtattta gaagcaatga ttcttccaac ttgacgcagc agttcaggtt ctcctaacaa
    45121 atcagagaga taaacatatc ctcctggaag cagacggtct tgttctgata gacgttctgc
    45181 tagagattca atatattttt tcgcctcttc atatgaaatt tcagggatga acaatacacc
    45241 acctgcagca cccgggattg tttccaaggt tccataccct cgttctttaa atgttttctt
    45301 gatgattccc aaatcttcac tgatagaaga tttagcagat tcataacgtt cggcaaagct
    45361 tgttaaggaa atcaattcat gcgggtgatt caataaatac tgtgtcatgt caactagacg
    45421 ttcactgcga cgtactttca cctattccaa ctccttttaa gaaattttat cgttttacat
    45481 tatataagtt tttcttcaaa aattcgagca ttttatgaaa aaataagaaa atagttcggt
    45541 atttattaaa ataaaaagaa gcctataaaa aatttttcgt ttttataagg cttcttttct
    45601 ttataattta gttatttttt cttctgaagg caaccaatat tcgtttgatg atatttacaa
    45661 tcaggaacaa agcaataaag actaatgtga ttgttgctcc tggaggtgta tctagataaa
    45721 acgagctagt tagtcctgac agcatcccta gaaatcctac acaaacactg atagcaatca
    45781 cgacattgaa gcttttgcct aatcgcatac cgattgctgc gggaagaacc atgattgcgg
    45841 atatcaaaag tgcaccggca atcgggatca tcacagcaat agccacacca gtaatcacat
    45901 tgaacatcat cgacatcaaa tgaacgggta gcccatccac gtgggcggta tcttcatcaa
    45961 aagtcagaac atacatcggc cgtttgaata aaaagaacaa tataccgatg gcaacgaata
    46021 agattcctaa aaagatgact tgctcccatg taatggtcac gatcgaacca aacagatagg
    46081 attggatact tgttgctgaa ttccctccgc tcaaattcat caatactaac gctagcgcca
    46141 aaccaccagc cattaaaatg gcaatggaga tttctgaata ggttcggtag atcgttcgca
    46201 gatactccaa tatcacagct gctaatacaa cgactagcat ggtcgtaagt gtaggattaa
    46261 ggttcaaaaa gaatcctaac gctacccctg ctaaagagac atgagaaagc gtatcagcca
    46321 tcagcgattg tcttctgatc actaaaaaca cacctagcat cggggcgatt ccggcaatga
    46381 agatagcggc aagaaacgct cttctcatga attcatatga aagcaacgcc attgagaatc
    46441 ctcctttctc accagtcgga tctgtctgtc cgcatactgt ttgatatctt catgatcatg
    46501 ggtgatcatt agaactgatt tcccatggac atgcgcacta tgtcggagaa gacgataaaa
    46561 ttcatttctg gattcttcat ccatacctgt tgttggttca tcaagaacaa ataagtcagg
    46621 gtcagtagca aaaatacgcg ctaaactgat tcgctgcttt tgtccgccag acaattcacc
    46681 tattcgccga tttcgcatat cccacatccc tacagcttct aaagcacgct gtacatgttg
    46741 atgatctttt tcagagagac gcttgaacca gcggcctctt ggatatcttc ctgaacggac
    46801 taattcgatc accgtactag gaaaacctgc attgaaagat gcaacttgtt gaggaatata
    46861 accgatactt aatttttttc cttcttgatt tttctcagca atctttatca ttccttttga
    46921 aggtttcagt aatcctaacg atgctttcac caaggttgac ttggctgctc cattttctcc
    46981 agttaaaatg acaaattcac ccgcatctac atgataagag acatcttcta gtacaggttc
    47041 atcatcatag taaaaggtca aatcagatat ttcgatataa cgcaccttac aacctccatt
    47101 ctaaaactta attgatactt tcttttaaag ctttcagatt tttttccatg acagaaatat
    47161 aattttcgcc tgctttgatt tgttcattag tcaagctttc taaaggattc aacacttcta
    47221 gcttcactcc tgtttcattc gacaatgtct cagctacctt cgaagaggca ttttcttcaa
    47281 aataaatcac tttgatgttg tttttcttca caaattcttt tagctcagct aagcgacttg
    47341 gtgtgggttc ctgatctggt gaaacgcccg aaatcgctac ttgttttaag tcgtattgat
    47401 tcgctaaata agcaaaagca gcatgctgag tgacaaatgt gcggtttgtt gcatctttta
    47461 gctcatcgga gtatttttga tccagtgctt caagcttttt gatataagca tcggcattct
    47521 tcgtaaaagt ttccttttta tctggatatt tttcgcctaa ttcttcagca atcgttctga
    47581 cttcttttat agctaatacc ggatcgagcc aaacatgtgg atcgtattca tgtgaatgac
    47641 catgcccttc ttctgattct tcatgttcgt ctgcttcttg cgattctaaa cggtcgattc
    47701 ctttagctgc ttcgatcatc aaggtctgtt tgctatccac tgaatccttt aacgaatcca
    47761 caaaaaattc catgtctgaa ctattataca cgaaaacatc tgcatcggaa atttctgctc
    47821 tttcttttgc acttggttcg aaatcatgcg gctccgttcc agcagggatc aaaagtttca
    47881 cgtttccttc atcccctacg atctcttttg taaaatcata catcggataa aaagtcgtaa
    47941 cgatcgtcaa atcctctttt ttgtctgctt ccttgttcgt atttccacat gctgcaaaca
    48001 gtaaagcacc tatcattacc gtagctgtca aaagatattt tttcatttat atgctccttt
    48061 caatgaacaa atcggaattt tacgatttat taacgtgaac taatgtatca aaataaaaaa
    48121 acacagtcaa tagaaatcca tcaatttctg atttaagcat gtatattctt gattaaatcg
    48181 taaaatggat gagttgctgc tcatatctag ccatttcact acaataaaaa actgaagaat
    48241 accattttag gattcctcag tttttcatca cctattttac ttcttatatt ttattgcagg
    48301 gttcgtacta aataaacttc ctcacaaaaa ccttttaacc cattatatac tctctgcgct
    48361 cttgaataat gttgacacaa ggcaaaaacg gttggtccgc ttccactcat caatgcagca
    48421 tctgctccgt acttgatcat acgctctttg atttgatgga tgactggatg ccgctttccc
    48481 gttatatctt ctaaactgtt tcccattttt ttgatcatct gctgataatc ttgctctcgg
    48541 atggcttcag caagtccgtg gatgtcttga tgttggatgg cttgcgtatc tacttctcta
    48601 aacactgtac gtgtagagac actcattctt ggtttgacca acacaaccca gcactgtggc
    48661 atagaaggta atacttggat ttcttcccct ttgccaccga caaatgccgt acttccgtag
    48721 acacagtaag gaacatctgt accgacttcc aaaccgattt ctgccagttc ttctaacgaa
    48781 cagcccagat tccataattg gttgatccct cttagagcag ctgcacagtc tgtacttcct
    48841 ccgcctaatc cagctgctac tggaatattc ttcttaacaa agatcttgac accggttttg
    48901 atattgtatt tattttttag caataaagca gcttgataaa cattgttccg ttcatctacc
    48961 ggtaaaaatg ctttatttgt ttctacaatg attttgtctt ctgttatttc ttcaaaaaat
    49021 agatgatctg ccaagtctac gctcgacatc accatttcca actcatgata cccatcttgc
    49081 cgtctatata atacatccag tcctaaattt atcttggctg gcgctttttc aatcaattcc
    49141 atcctctcac ccattcgaaa agtctaagtc gcaagtattc tatcataggg aaaaataaaa
    49201 gtatagctta tgtctgccta gtggttgatt ttgtcatcgt ttcaacagct ttcacagaat
    49261 tttctcttca taatccaaac aagttctagt gattcttata attctgtgag cacttcttct
    49321 gccaaactcg gaacatttcc tttttctttt cctatcagac tgagtagctg catggtagca
    49381 aatccgaaat tacttccttt cctataagca aaataacgtc cttcccaatg atcgacatat
    49441 tttaatttct tttcataagc agactggaag gaatagaaaa aattaccata attatatacg
    49501 atatgcatga ctttttcttg aaagaaagaa aaatctgttt ctccaacatt agctaatgga
    49561 gctaagccta gattggcttc cgagtagccc attttctcgt atacaataaa cagattggct
    49621 aacagatagt cagctaattc ctcagattct ttaggtaaga cccgcaacaa atcatatccc
    49681 gcctgcttct tcgtcatcgg ctgagcggtg atgaagccaa cgactttttg atctttacgg
    49741 acaataccga caccgctaga taatacatat gatttatcaa atcgtcccac agagaagtat
    49801 ttttctcgtg caccttgaag ccatttttgt gaaacttcat ttacagcttg atgtaattct
    49861 tccggcagtt gatcgtacca agtaaaatgg tatccttctt tcatcaaacg ttgatattca
    49921 agttgctgac tcagccgaga caagtcttct gttgctagat caacaatccc tgcttcacct
    49981 actttcgtga agtgaaaacc caattcatga agcatcacta cgtagctttc tgatatctta
    50041 taaaacgcaa gctgatagcc taaacaatct gcttgtttca taaactgatt cgttgctgcc
    50101 cgcatcattt taggattgcc aactggatct cctaaaacaa agcatttgtt tcctttgatc
    50161 tgataaccaa aaacgacttg atcttggtcg tcttcttggt aataaaaata actgtaacct
    50221 gacaagcgaa gctgatggct tgtagctgtg cctccgtatg tttccaataa acggtcaaaa
    50281 cggtcttttt cgtactcact gccaagcttc gtagtatctt cagctaaata ttgataaagc
    50341 gccactaaag ctagcaatga gatgcccaaa ccaataagcc ctgagaacca cacatcatct
    50401 gaaggaaaca aaataaaatg atttcctgtt attcgaccga ctaaaaagcg tccgctgtga
    50461 tagcctgcaa ttgcgtaaac gataaacaaa aagccgaaca agctagcatc aaagattata
    50521 gctccccaag aataaacgaa ttttgttcga taaaattctt ttctggataa ccacacagct
    50581 aacagaatca agacatatac caatatcaac tgccaagata acgtacgtgt gattgtattt
    50641 aaaataccaa aagatagtaa agcaatcgta ggcagaaatg cctttttgac ttttactgaa
    50701 agtgctctag caaggccgag taataaaaag ccaaccaata gattcactgt ctgatctaaa
    50761 aaattgaatg agaacggcaa taatacttga aatagccgac tgattgcaga cagattagtg
    50821 attgttgata gaagtaccat catgatcccc gcaaaataga cagcacttac gagcacgata
    50881 tgcgcaacct tttggaaaaa cagtcgcgga atgttatcta aaaatcgatt gattttgact
    50941 cctgtatgtg tgatgaacaa tagaagtccc gtcataaaag gtagaacata ataaaacaac
    51001 cgataatata atagccaaac tactgctaca tcttgccgaa cagacaattg actcattcct
    51061 aagatcatca aaacgtcaaa agtccccatt ccacctggga ccatcgtcag cattcctatc
    51121 aatgtagcaa tcatgaacat aggatagatc gaaagcatcg aaatatctat tctcatcaac
    51181 ttgccgatga tcaaaaatac cgcaagggct cccgtccatt gtccaaagga tgccagtagc
    51241 agaccaagca agccttttgg ataaaactcg aagaacaatg tctttctctt tagataagca
    51301 aaaaagaaaa tgactggtgc taaaaaacta ccgccgaaaa gccagatcca atagcttcga
    51361 aaaatacttt ctgactgaat aaaaaagaca tcaataaatg taagaaacga ccatacagac
    51421 aaaccagtca gcataaatag tgcgactttt gatacagtgg ctaaaaccat ttttctattt
    51481 gtctgctttc cataaaaact agcccgcaga cttgctccta ccacaccacc aaaaccggcg
    51541 agattgttga tcgtgtttgt tacccacgca gcaagaagaa actcttttct ttccattttt
    51601 ggttttcctt gtttttctaa gactctgatc gtcacccaat catacaacaa catcggagtg
    51661 acacccagca gtccagccag aatcatgagc aggatcgtca tgcggctttg ttgtcccatc
    51721 ctttgccaaa tatcttgcca actcatgcca ttagcaatat ttgcgacttg atttgccaca
    51781 aagactaaca cggagccgaa aaaaatcagt tttaaaatca gactatgttc ctttatccat
    51841 tgcagcatca agtatcgttt atttttcaca ttttcccatt cctaacttgt atacttttgt
    51901 gtcatacccc aatgttatct tatttatttt aatttttcca ctttagacct gttctttgct
    51961 tgcgatgata gaaaaagaaa gatatcctaa tgctaaagga gaggataaca tgaaagtagg
    52021 atttatcggc acagggaata tggcacaagc tattattgat ggtttattaa aaaaaggaac
    52081 agtctcgaaa gaagaggtgt tcgtttccag tggacatttt gaaaatgcac aaaaatttgc
    52141 tgctgaaact ggcgtccatg catgcaaaag taatcaggaa gttgcatcac aatcagatat
    52201 cgttctttta gccgtgaaac caaaaatcat tgaaaaagta ttggaagaac taagagaata
    52261 tagccagaaa gtcttattca tttctattgc ttcaggaaaa tcattaacag atttagaaac
    52321 agcgcttgaa gatcctcagg cctccatcgt acgtgtgatg ccgaatgtca atgtcagcgt
    52381 aggagcaggc gtttctgcga tttgcaaaaa tgaagctgcc acggaggaac agcttcagca
    52441 agctacgatg atttttgaag caatcggcag cgtctatcct ttagcagaat cagatttcag
    52501 tacattcatt ggccttgctg gcagctcacc cgcattcgtt tacatgctga tcgatgcgat
    52561 gggacggact ggtgtactga atggtttgtc caaacagaca gccactgaga ttgctgcaaa
    52621 agcaattatg ggttcttgtc aaaaattcct ttcaagtgat aaaaatccat gggaacttgt
    52681 agaccaagtt tcttctcctg gcggtacaac tgttgcaggt gtagttgcct tagaagaagc
    52741 aggattcatc ccagcaatca tcaaaggaat caatacgacg atcgagaaag atcttgagat
    52801 gttgaataaa aaataatgat agcaatgttt tttcgtacct tacaaaaaaa gaagagctgt
    52861 ggcttttgcc gcggctcttc
//
LOCUS       DARPZF010000014        50590 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.014, whole genome shotgun sequence.
ACCESSION   DARPZF010000014 DARPZF010000000
VERSION     DARPZF010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.014"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            131..505
                     /locus_tag="SLE65_001122"
     CDS             131..505
                     /locus_tag="SLE65_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HEI8448430.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="SLE65_001123"
     CDS             complement(619..1248)
                     /locus_tag="SLE65_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEI8448431.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="SLE65_001124"
     tRNA            complement(1382..1454)
                     /locus_tag="SLE65_001124"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="SLE65_001125"
     tRNA            1668..1741
                     /locus_tag="SLE65_001125"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="SLE65_001126"
     CDS             complement(1879..2043)
                     /locus_tag="SLE65_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448432.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="SLE65_001127"
     CDS             2338..3666
                     /locus_tag="SLE65_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HEI8448433.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="SLE65_001128"
     CDS             3868..4701
                     /locus_tag="SLE65_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HEI8448434.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="SLE65_001129"
     CDS             4717..5454
                     /locus_tag="SLE65_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEI8448435.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="SLE65_001130"
     CDS             complement(5609..6577)
                     /locus_tag="SLE65_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEI8448436.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="SLE65_001131"
     CDS             6809..7642
                     /locus_tag="SLE65_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HEI8448437.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="SLE65_001132"
     CDS             7676..8515
                     /locus_tag="SLE65_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEI8448438.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="SLE65_001133"
     CDS             8541..9101
                     /locus_tag="SLE65_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEI8448439.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="SLE65_001134"
     CDS             9300..11021
                     /locus_tag="SLE65_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEI8448440.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="SLE65_001135"
     CDS             11186..12328
                     /locus_tag="SLE65_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEI8448441.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="SLE65_001136"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="SLE65_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEI8448442.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14775
                     /locus_tag="SLE65_001137"
     CDS             14128..14775
                     /locus_tag="SLE65_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEI8448443.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14904..15120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15168..17813
                     /locus_tag="SLE65_001138"
     CDS             15168..17813
                     /locus_tag="SLE65_001138"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEI8448444.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18123..19436
                     /locus_tag="SLE65_001139"
     CDS             18123..19436
                     /locus_tag="SLE65_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEI8448445.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19426..20079
                     /locus_tag="SLE65_001140"
     CDS             19426..20079
                     /locus_tag="SLE65_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEI8448446.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20134..20805
                     /gene="radC"
                     /locus_tag="SLE65_001141"
     CDS             20134..20805
                     /gene="radC"
                     /locus_tag="SLE65_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEI8448447.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGIYKLVHINYIRKFTVILPSGNTIMLSIIERHNAFFSS
                     SEDSL"
     gene            complement(20700..22052)
                     /locus_tag="SLE65_001142"
     CDS             complement(20700..22052)
                     /locus_tag="SLE65_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8448448.1"
                     /translation="MKRVALYMRVSTEQQAKHGDSLREQKETLYEYIEQHKDLKVVNE
                     YVDGGISGQKINRDEFQKLLQDVKENKIDLILFTKLDRWFRNLRHYLNTQEILEKHNV
                     SWNAVSQQYYDTTTAYGRTFIAQVMSFAELEAQIDSERIKAVMANKIAQGEVVSGKTP
                     LGYSIENKKLVINDDAPIVIDIFNYFLSSGSLRKTVYYLGSQYGIVRDYQSVKNMLTN
                     KKYIGELRNNKNYCPPIIDKKLFYAVQKALPKNLKTNAKRDYIFKGLLKCSDCQGSVA
                     GQTIKARYKKKDGTESIYERTCYRCVKRRNNKLRCTNKRAFYEKNLERYIFEATKQKF
                     EQIQINYSKKQPKIIKKKNSKKNIENKLDRLKKAYLNEVIDLEEYKKDREALMKELNE
                     IEVEPAKIDIKNVEFILSKEFDEIYKESSEEEKNALWRSIIDNIIVFPDGNITVNFLI
                     "
     gene            complement(22118..23407)
                     /locus_tag="SLE65_001143"
     CDS             complement(22118..23407)
                     /locus_tag="SLE65_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEI8448449.1"
                     /translation="MGVLLFLVGIVLIIMGSSKLSEAKKLKDKTSALESKVKEYSQEL
                     NARETFISEKEKNISKLNKNLSTLENKIDILNAESQRLDDEINQKYDTSLVTIYKSVI
                     IPNIDETSSSEIKNKLSLLKIKEKDFILDGAINIPSYLNNREANNIKKKMLIPLESEI
                     TGLLNKLTISNVDSTREKIIRTFDKINKLFKNDEAEFKKELLELKLQELELNYSYIVK
                     VNDEKEQQKAIKEQMIEEEKVRREIEREKKRIDKEERQFNSEITKLMAYMQKASADVE
                     KELYADKIKELEEKLRELETVKEDVLQRELNTRAGYVYVISNIGSFGEDVYKIGMTRR
                     LEPMDRIKELSSASVPFEFDVHAMIFSEDAPTLENQLHSHFRKNEVNKVNQRKEFFKV
                     SLDEIEKVVLENYNGTVSFTKLAQAEQYRRSLELTDV"
     gene            complement(23494..24198)
                     /locus_tag="SLE65_001144"
     CDS             complement(23494..24198)
                     /locus_tag="SLE65_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HEI8448450.1"
                     /translation="MFAENLKFLREKYNIDQQELAEKLGRKSSSSISEWEKGKYTPKL
                     KTLNEIAKIFNVDIDDLMNIDLSISNQIYNILPIYNQLNDENKVATYEFASNRLEEQK
                     QENVLDFPKKEKIPTVHNSASAANPTELTYGDTVVEEEEFERVPSAADFAVPIIGDSM
                     EPVIRNGQFVFVKEQPDVEDGEIAIVELGGDGVTCKEIYKDYENQTIILRSINDLYED
                     RIVSPEQIRIIGKVVF"
     gene            24398..24664
                     /locus_tag="SLE65_001145"
     CDS             24398..24664
                     /locus_tag="SLE65_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8448451.1"
                     /translation="MDTAKKEKYTLRQLRALKGYSKEELSRKSKVTSRTIFIYENDVD
                     KMRNGKYATLEKIAKALGVRVSDIFLDPDSEKPKSITGETKQVS"
     gene            24677..24835
                     /locus_tag="SLE65_001146"
     CDS             24677..24835
                     /locus_tag="SLE65_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448452.1"
                     /translation="MEEKNIKVPTLEEYTKIVVETDEQNPKTIAVITANDIESCEGFR
                     VRMTPRYD"
     gene            complement(24832..25062)
                     /locus_tag="SLE65_001147"
     CDS             complement(24832..25062)
                     /locus_tag="SLE65_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HEI8448453.1"
                     /translation="MGKNQWVSPRNGKWAVRGEGNSEDTKLFDNKSDAVEYGKKISKK
                     QQSEFIVQKKNGQIQSKDSFGNDPIPPRDKEH"
     gene            25134..25289
                     /locus_tag="SLE65_001148"
     CDS             25134..25289
                     /locus_tag="SLE65_001148"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448454.1"
                     /translation="MSNKPKITLNGTPNLQRLADEMARIRSRHWGVTVVATIIEQKEK
                     PTQPASK"
     gene            25446..25601
                     /locus_tag="SLE65_001149"
     CDS             25446..25601
                     /locus_tag="SLE65_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448455.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGEKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(25598..25822)
                     /locus_tag="SLE65_001150"
     CDS             complement(25598..25822)
                     /locus_tag="SLE65_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HEI8448456.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            26089..26424
                     /locus_tag="SLE65_001151"
     CDS             26089..26424
                     /locus_tag="SLE65_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448457.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            26657..27598
                     /locus_tag="SLE65_001152"
     CDS             26657..27598
                     /locus_tag="SLE65_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HEI8448458.1"
                     /translation="MSKSTLEMSHQEWLEDRKRGIGGSDVATVLGLNKYKSPYQLWLE
                     KTGQIELKDLESEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPVIDGSGATADFLKEKYADVEENQTA
                     LPSRFDELIEQKRELKRTKKEIESSIRQVDNEIISELGKREASIGITQRNIISWKLVR
                     TRRMNTKKLAEKYPDVANDEEIYNVTESRRLTEKEIK"
     gene            27600..28490
                     /locus_tag="SLE65_001153"
     CDS             27600..28490
                     /locus_tag="SLE65_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HEI8448459.1"
                     /translation="MATNESLKNQLAEKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            28533..29333
                     /locus_tag="SLE65_001154"
     CDS             28533..29333
                     /locus_tag="SLE65_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEI8448460.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWSLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            29348..30199
                     /locus_tag="SLE65_001155"
     CDS             29348..30199
                     /locus_tag="SLE65_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEI8448461.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGSIA"
     gene            30196..30555
                     /locus_tag="SLE65_001156"
     CDS             30196..30555
                     /locus_tag="SLE65_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HEI8448462.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELEGKKYRKIEYIPDFTFYKSGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            30570..30731
                     /locus_tag="SLE65_001157"
     CDS             30570..30731
                     /locus_tag="SLE65_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEI8448463.1"
                     /translation="MTTEEVIQMRIRSLRREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            30728..31054
                     /locus_tag="SLE65_001158"
     CDS             30728..31054
                     /locus_tag="SLE65_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448464.1"
                     /translation="MSVDKEAAWRKLMLLIQDENWQEDEAVVAEVQRLGKIANGRIRK
                     KPDKRKQRKGKIVVVLHEGKILMQGTASELSAETGYTRGTIRTYAWRNHTDRKGHEYK
                     YLEEEK"
     gene            31051..31866
                     /locus_tag="SLE65_001159"
     CDS             31051..31866
                     /locus_tag="SLE65_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HEI8448465.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            32005..32316
                     /locus_tag="SLE65_001160"
     CDS             32005..32316
                     /locus_tag="SLE65_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HEI8448466.1"
                     /translation="MDELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEDV
                     K"
     gene            32313..32543
                     /locus_tag="SLE65_001161"
     CDS             32313..32543
                     /locus_tag="SLE65_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448467.1"
                     /translation="MKYEIPLSEAGIQAIINGREVNIELPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSIDDTFRLGS"
     gene            32550..32753
                     /locus_tag="SLE65_001162"
     CDS             32550..32753
                     /locus_tag="SLE65_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HEI8448468.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASDAIRKFGISILNDDRKWEEMR"
     gene            32750..33049
                     /locus_tag="SLE65_001163"
     CDS             32750..33049
                     /locus_tag="SLE65_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448469.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EEFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMEVINNEV"
     gene            33039..33203
                     /locus_tag="SLE65_001164"
     CDS             33039..33203
                     /locus_tag="SLE65_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448470.1"
                     /translation="MKFKIFEEDTRYKLEKELNDFAKNNEIQHISLATSKRGYANYYA
                     AVVSYVSREV"
     gene            33292..33705
                     /locus_tag="SLE65_001165"
     CDS             33292..33705
                     /locus_tag="SLE65_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HEI8448471.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILVALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            33718..34104
                     /locus_tag="SLE65_001166"
     CDS             33718..34104
                     /locus_tag="SLE65_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448472.1"
                     /translation="MWKDYVSLKELKKDLVFKRIVEWSESELILEDGTKMEVVCSESD
                     CCAWAEGEFKNVKLDAVITDIKIFDKGNRLYNGDGHTSYAEVVVYHNRNEIAKAECTA
                     NDGNGGYYYSVCALKVKDKLCIVTDA"
     gene            34655..34879
                     /locus_tag="SLE65_001167"
     CDS             34655..34879
                     /locus_tag="SLE65_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448473.1"
                     /translation="MRTYWYVSLNNKYPKPMKGQHRRVVMSVQMKAKYSIVEMIREAT
                     PVEIDYCKLVYCGCGRWKEDHVQKNISKYI"
     gene            34897..35325
                     /locus_tag="SLE65_001168"
     CDS             34897..35325
                     /locus_tag="SLE65_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448474.1"
                     /translation="MEKSDTKANRYKPTAAEKKLLEVLINPDNLGKPVQELCSLAKIG
                     RTKYYDAMSKDGFVDLVNETTMDLIKGKASDVLNATYKYALTEKGHQDRKMILTIAGI
                     YADKQELKHSGGVDIRKQYEKMSDEELEELVKRYEKINDS"
     gene            35303..36721
                     /gene="terL"
                     /locus_tag="SLE65_001169"
     CDS             35303..36721
                     /gene="terL"
                     /locus_tag="SLE65_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HEI8448475.1"
                     /translation="MKKSTTLNRVEYAVVQRELAIRKARKSFWLFCQLLYPEFYKDDR
                     LYLKDLCHTLQDFYEDKIDKKILVINMPPRHGKTFTARLFVLWMFGQNPKTKIITGSY
                     NQILSSLFAQQTRDGIMVENENVKAEYFKDIFPEVQIKYGDAAKGFWSLDGSEEKNYL
                     ATSPGGTSTGIGANYVIVDDIIKTAEEAYNERVLDSHWEWYNNTLAQRMERPRKQILI
                     MTRWSSNDLAGKMLTRRKNNVHQICYKAVQEDGSMLCNEIMTHDEYLDVVQEMNVDIA
                     EANYQQEPIDQKGRLYQKFLTYDTLPDNIIKIWNYTDTADKGADYFASPVFAETSDHD
                     AYIIDVMYTKEPMETTEIAHANMIIRNRVNKVRIEGNNGGRGFRRNSERITKERGYRG
                     AVFEDFHQSDNKLSRILANSAWVENHVYYPDDWATRWPDFYEAMVSYQREGKNAHDDA
                     PDAVTGIAETIIEADDFEFIAY"
     gene            36733..38268
                     /locus_tag="SLE65_001170"
     CDS             36733..38268
                     /locus_tag="SLE65_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010779952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEI8448476.1"
                     /translation="MFYSGITLKKYKRLRTKYSTQIEEGLFDPNAFMEDMKPFFDDRE
                     RKYLAYTSEKNEIDSREKPKTKIIKVNNKIHAGMYSVVVDQAVNHFTGIPIKWDYDVS
                     EQKRTFIQRMRDKLLGNDISAPSTPEEFETLTRQLSTMRFGMLDPDTATFQGATGLAF
                     RLLEPVETNDGWELRASNIEPWKAEKYENGAVYIKEKYDPYQKKFYEEMKVVTPKSIF
                     TYARYTDYPGTVQGAFKTLGNVPNPLGVINLTEFKNNTNRYCDFEVAEEISDAIDRVL
                     SDQQNEIEQFKLAYMLITGADLSEDKAKKMMEQLGIINLKDPNAKAGYVTKDLQKDFN
                     EYHFDLLKKQFYTVCKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAEVMAAYLDFAEKVTIDPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMIDVESRQSYPDGEYGGGIVESNRNEVLDQTSRTGRFSKTQNGKSNAK
                     ETK"
     gene            38348..39226
                     /locus_tag="SLE65_001171"
     CDS             38348..39226
                     /locus_tag="SLE65_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEI8448477.1"
                     /translation="MMEFYSTSDQKKYREYVEKNYKSLKMYDAKYKEFIEEYFPSFDY
                     AKVNRLLQMRSDIFRILAESAIDADVNKYFSDRLEDILQRSYVSNANVFAQILNVDLP
                     NYLSKEELERYLNYPWSGKTFSRRLWGNISSLEQKLSNAITTSVASGEGVLVALRTMR
                     EDPEICDMFKREESKYNKAIENLVRTEYAKFAQDGIEKSYIETGVDEYNVLTAKDEKV
                     CSICGGKAKNNPYKLSEAIIGENRAPFHGRCRCTDVPNMPKLGKDIDEEYERLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            39228..39545
                     /locus_tag="SLE65_001172"
     CDS             39228..39545
                     /locus_tag="SLE65_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448478.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYENMGCIVVRTDYKEGK
                     SSN"
     gene            39672..40295
                     /locus_tag="SLE65_001173"
     CDS             39672..40295
                     /locus_tag="SLE65_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEI8448479.1"
                     /translation="MIMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            40310..41200
                     /locus_tag="SLE65_001174"
     CDS             40310..41200
                     /locus_tag="SLE65_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HEI8448480.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            41223..41438
                     /locus_tag="SLE65_001175"
     CDS             41223..41438
                     /locus_tag="SLE65_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448481.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            41450..41791
                     /locus_tag="SLE65_001176"
     CDS             41450..41791
                     /locus_tag="SLE65_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448482.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            41791..42162
                     /locus_tag="SLE65_001177"
     CDS             41791..42162
                     /locus_tag="SLE65_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448483.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            42155..42550
                     /locus_tag="SLE65_001178"
     CDS             42155..42550
                     /locus_tag="SLE65_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEI8448484.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            42552..42929
                     /locus_tag="SLE65_001179"
     CDS             42552..42929
                     /locus_tag="SLE65_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448485.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            42930..43538
                     /locus_tag="SLE65_001180"
     CDS             42930..43538
                     /locus_tag="SLE65_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEI8448486.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            43538..43879
                     /locus_tag="SLE65_001181"
     CDS             43538..43879
                     /locus_tag="SLE65_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448487.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            44121..46910
                     /locus_tag="SLE65_001182"
     CDS             44121..46910
                     /locus_tag="SLE65_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEI8448488.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNGGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVASSMESFLKVIAANIPRAVSFLSNLFDAVQKFGSALKFMMPFLVPA
                     TTAFGALMFQLKGIPTIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIVGAVVGAI
                     AVFGYFMATNEEVRNKVISVWNDVKDSVLGVLKNIKDWGIDTWNSAKEMASNAVESVK
                     DAWSGIKEWFSNTWQGIKNGATGLFDKTVETSMNAVDSVKNAWSNTKQWFSDIWQSIK
                     DSATEKWNEIKGSIMEVAGPLITGLKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LTPVLFITSMISGGWEETKNNMIGVWNNIKESALNIWESIKNIFVSYITNIYFAALNI
                     WTGFKLTLINIWNEVVSQAKSIWINVKYFFINLWIDIKYFAIQKWIELKFGIIQTWID
                     LKYNAITTWNNIKQFFKDTWQNIKDIAYNTWISIKNSMINTWNNIKESFWNIVTGIVN
                     SAENAWTNLKNGVSKAINRVKEIFDSLREINLFEIGKNIIDGLINGVVEKWNALKKTI
                     KGIAGSIKDSIKGALGIHSPSRWMRDMVGKNIVQGIIVGIDKEKSKLDQTMTDLVKTP
                     SVQPVITGSNSQPVVQAKQNTSSNAVNEIHLHLNVYGDLPDSMIKQIAKKMKTELTRQ
                     MKRDADAVGGTLYAT"
     gene            46900..47640
                     /locus_tag="SLE65_001183"
     CDS             46900..47640
                     /locus_tag="SLE65_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEI8448489.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKAYYKNVTRKIECYYKAPSIDLVQEWEDRITEWLDMNSYSDFILYYDQQYIYQ
                     AIVTEAPEFKGTRKTGNIVPFEFTVSLRPFKENYSGRFAIQQIKAFELFNPEKYASKP
                     LIKLSGSGDASFYINNDKYDLKLLDRELYIDSKLEESYRKLDDNLEHQDHVTLFLDFP
                     FLYPGKNEIKWTNNIHSFEIIPRWWRKV"
     gene            47637..50348
                     /locus_tag="SLE65_001184"
     CDS             47637..50348
                     /locus_tag="SLE65_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HEI8448490.1"
                     /translation="MIPRIYSPTETDFSTNGLGILKDTTKCEIYEVANGKYELELEYP
                     LGTRFDEYFENDYQIKAKSNDQEEYHIFFIDDKDIDTFLDTVTIYAQSRTNRLGRRAV
                     TFAGVDSKTGREAMAIIENNMDKKSDIRLYSDITTVSSTTFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRDNIGTIRYGKDLSGLKVKLDWTGVKTRIIPYADPQS
                     DAGTTSRIYGSPVDSEYINNYPDVYTEHVQFTEEQGVKDVNSLNKIAKNYFKTINPGC
                     DKPKISITVEFDKLTDTEEGKEFAKIRNYGLFDTFKIYHRKYKLYFESKVSGVQYDSL
                     SEKVLKLEAGDAQVAFYQQQAVTIQDKLKDYATNNYMSSFNDYVSSMIAGQGNAGGYV
                     VLWPKEKPSNIFIMDSPDLNKAKEVLRMNKNGIAFSKNGWNGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSNSSIGTI
                     GTTDSAGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVNGKEITGNNSGGSDPGTIPPQLTTEAEKRAWKIWTMLKARGYSEYAAAG
                     ILGNIQGEVGASMNPDTEQLGGPAYGIVQWDGSAYPLVGSPTWNGREYVQRLMNTAGI
                     QEDYRSIEAQVKLLDWCMFNGQWLGKVNPTTVSGFKSINDAKSAAYAFEMNFERPASA
                     HPERQNYAQSWYNKLHGLTSPEPGGNFICPIQKPVTVTSECGWRTSPINGGQEFHNGI
                     DLVNGNPNTPVFAALDGEVVQAGANYYDWYGNYVVIKHNNGKWTGYAHLSRIDVSVGQ
                     KVQKGAQIGLMGTTGPSTGEHLHFQIMKNYWPQPVVDFENPRNYIQF"
     gene            50361..>50590
                     /locus_tag="SLE65_001185"
     CDS             50361..>50590
                     /locus_tag="SLE65_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HEI8448491.1"
                     /translation="MSKWNVVLSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKI"
BASE COUNT        17443 a         7976 c        10424 g        14747 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaattattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaaga tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggctatga tgtccctttt
    14341 cttatcgatg tattcaataa tatccttaat actaaagaag aaaaacgaat cgcattagta
    14401 ggatatggaa atcttggcaa agcattgaaa cacaacaatt ttagaagaaa tgaaaatcta
    14461 aatatcgtgt gcgtctttga taatgatcca gcactgatca atcgagtaat tgatggagaa
    14521 atgatctatc cgattgatcg tttcgcggag atagccaaag caaaaaatgt gacagtagca
    14581 atctctacgg taccaagtaa atattcacaa tctgctattg atgaaattgt caaaggaaat
    14641 gtaaccgcta tacttaattt tgcgcctgac agagtaactg tcccagctta tgtcaatgtt
    14701 caatacattg atttgacaac cgagttgcag acgcttattt actttgatga gaattactca
    14761 gaagtttttt cttaggaaaa tttgagtagg cttattgatc ttgcgagaac tcgtcgtaat
    14821 tctttcaaaa attttttagt actaaatgaa gtggtttttt cacgaccact tgttgactaa
    14881 aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa gaggagtaac tggcacattc
    14941 attcttagag agagaactat ctgctgaaag gttctcaatg acaaccagtg aaggtagctt
    15001 gggagtttct gtcttgaatg gagtagagat agacgagtcg tgatcgttaa ctcacttgag
    15061 aggcaataat gattgattat tgcaatttag gtggtaccgc gtaaatcata cgtcctagaa
    15121 tacgaaagta ttttaggacg ttttttagtt taaaggagga aaacagcatg acggaagaaa
    15181 ataacctatc aacaaaatat aatccgcaag aagttgaagc tggacgttat cagcattggt
    15241 tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc aaaaccttat tcaatcgtaa
    15301 tcccgccccc aaatgttact ggaaaacttc atttagggca tgcttgggat acgaccttgc
    15361 aagatatgct gattcgtcaa aagagaatgc aaggatatga tactttatgg ctgcctggta
    15421 tggaccatgc aggaatcgcg acacaagcaa aagtagaagc gaagcttaga gagcaaggga
    15481 tttctcgtta tgatctaggt cgtgaaaagt tcatcgatca agtgtgggaa tggaaagaag
    15541 agtatgcgag ccacatccgc gaacagtggg ctaaaatggg cttatcttta gattacagta
    15601 gggaacgttt tacattagat gatggattat ctgaagcagt acgtaaagtt tttgttacct
    15661 tatacgaaaa aggtttgatt tatcgtggtg aatatatcat caactgggat cctcaagcac
    15721 gaacagctct atctgatatc gaagttattc ataaagatat cgaaggcgcc ttttatcata
    15781 tgagctatga actagcagat ggatcaggcg tagtagaaat tgcgacaacc cgtccagaaa
    15841 cgatgttggg agatacggcg attgctgttc atccagaaga cgagcgttat caagcgctca
    15901 tcggcaaaaa agtgattcta cctttagtca ataaacaaat cccaatcatt gcagatgaat
    15961 atgtagatat ggaattcggg acaggtgtag taaaaatcac tccagcacat gatccaaacg
    16021 actttgaggt aggtaatcgt catgatcttc cacgcgtaaa tgttatggat gatgatggta
    16081 cgatgaatga actagcagga aaatatgctg gaatggaacg ttttgctgct cgtaaagcaa
    16141 tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat cgatacgatg atccacagtg
    16201 tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg gctgtctact caatggtttg
    16261 taaaaatggc gccgttagcg aaaaaagcca ttgataacca agaaacagat caagcagtgg
    16321 aattcttccc tccaagattc aatcaaacgt ttttacgttg gatggaaaat gtccatgatt
    16381 gggtaatctc acgacaatta tggtggggac atcaaattcc tgcatggtat cacaaagaaa
    16441 caggtgaaat gtatgtaggg atggaagcac cagcggatag tgaaaactgg gtacaagatc
    16501 ctgatgtttt agacacttgg tttagttcag ctttgtggcc tttctcaaca atgggctggc
    16561 cagatacgga aagcgaagat tataagcgat acttccctac tagcacttta gtaaccggtt
    16621 atgacatcat tttcttctgg gtaagcagaa tgattttcca aagcttggaa tttactggcg
    16681 aacgtccatt tgagaatgtc ttgattcatg gattgattcg tgacgaacaa gggcggaaga
    16741 tgagtaaatc attaggtaat ggaatcgatc cgatggaagt aatcgaaaag tatggagcag
    16801 atgctctccg ctggttctta tcgaatggtt ctgcaccagg acaagatgtc cgcttcagct
    16861 atgaaaaaat ggatgcttct tggaacttta tcaacaaaat ctggaatgct tcacgtttcg
    16921 ttatcatgaa tatcgaagga atgaccgtag aagagatcga tttatctgga gaaaaatcag
    16981 tggctgaccg gtggatcctt actcgtttga atgaaacgat cgaacgagta actgagctat
    17041 ttgatcgttt tgaatttggt gaagcaggtc gacaactgta taactttatc tgggatgatt
    17101 tttgtgactg gtacatcgaa atgagtaaag aagtacttta tggagatgat gctgtttcaa
    17161 aacaaaccac ccgtagcatc ttagtccata cacttgatca gatcctacgt ttattgcatc
    17221 caatcatgcc attcgttaca gaagaaatat gggaacatat tcctcatcag ggaaattctc
    17281 tagtagtggc agaatatcct gttgtacgtc cagagtttga tgatgaaaca gcttctaaag
    17341 ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa tattcgttca gaagtgaata
    17401 caccattgtc taaaccaatt acgttgctaa ttaaaacaaa cgatgctaaa atcgatcaat
    17461 ttttagttga aaatacaagc tatatcgaac gcttctgtaa tcccgaagag ttgacgatat
    17521 caagtgagat cactgcgcca gatctagcga tgtcagctgt tctgacaggt gcagaaatct
    17581 tcttgccgtt agcaggattg atcaatattg aagaagaaat caaacgatta gaaaaagaac
    17641 tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa actttctaat gaacgttttg
    17701 tttctaacgc gccggaagaa gtagtagagg cagagcgtgc aaaagaaaaa gattatttag
    17761 agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg tactattcaa taagaataga
    17821 aaaagagagt gtgaaatcag ctagctatta ctaaaagcta gctgattgaa catcgttaca
    17881 ggaaagagtt tgagcctcac tcttagcttc gattcataag gagatgtgac ataaattttg
    17941 tcgcatctct tttttagtct actcttatta tgtaggagaa ggagggaggt ggatcatgta
    18001 tcaagagtca ataaagtagt tgataaaatc gttcctctct ctgtttcttt tctctttgtc
    18061 atacttttat ttttcttatg tgttctattt gttataataa aagagaaatg ggggaattgt
    18121 tgatgacgat tgaagaagca atagaatgga tccatagtcg attaccattt ggttcacgtc
    18181 ctggccttga ccgagtcgaa gctttattag aagtggtagg gcatccagag agaaaagtaa
    18241 aaacgatcca tatcgctgga acaaacggaa aaggttctac tgtagcttat ttgagaagcc
    18301 tattagaaga ggctgggctg acagtaggta catttacttc accttatatc gaaacgttca
    18361 atgaacggat cgcaatcaat ggcaaaagca ttccagacaa tgatttgatc cagcttgtaa
    18421 aaaaatatca gccactgatc aaacaacttg atcaatttga agcagtagct ggtattactg
    18481 aattcgagac attaacagca atggcatttg attatttttt gatgaagaaa gtggacgtag
    18541 cgattatcga agttggctta ggcggcttat tggattctac caatgtagct gtaccaatgc
    18601 tgacgggaat aacaacgatt ggacttgatc ataccgaaat acttggagat acaattgaag
    18661 aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt tccagtagta acaggaaata
    18721 ttgccccaga agcttttact gtcatccaac aaacagctaa agcaaaaaat gcaccgcttt
    18781 atgtatacgg ggaaaattat aaaataaact atctgcatcc tgatgagatg tggggagaag
    18841 tatttgaatt ttttaatgaa ataggaaaga tccctcaatt aaccactccg cttttagggc
    18901 aacatcaagc tgaaaatgca ggagtagcca tcgaattgta ttttgtttac tgtcaattgg
    18961 aaaagctgcc tttccgagaa aaagatgttt tgaagggatt gaagaaatct cgatggccag
    19021 gaagaatgga gcgtttgagt aacgagccat tagttgtttt agatggtgcc cataatacgc
    19081 atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt caaaggatat caaatcaaca
    19141 ttttgttttc cgccttacga actaaaaatg ttagagaaat gctagaacga ttgcagcaag
    19201 taccaaatgt ccatatttat ttgacgacct ttgaacatcc aaaagccatc gaattaagtg
    19261 aagtatcaga tttagcaagt gagagagtat caatcgtttc attgtggcaa ttcggattag
    19321 cagatatatt ggaaaagatg acaaatgaag acgtattagt tgtgaccggt tcactttatt
    19381 tcatttcaga agttcgccat ttattaatac aattaggagg agatcatgaa gtataatgca
    19441 gtgatttttg acatggatgg tttgctgttc gacacagagt tagtgtatta cgaagccaca
    19501 caagtagtag cagacaagat gggttttcct tatgataaag acctgtattt aaaattctta
    19561 ggtgtttcag atgaagaagt atgggcgaat tatcatatga ttttctcgga atttggcaaa
    19621 acaagtgtac aaagattcat agatgattca taccaggaaa cgcttgaacg tttttcgcaa
    19681 ggagcggtac aaatgaagcc cggtgtgttg gaactcctct cttttttaga agaacatcag
    19741 attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca ttgaactttt attgaagaag
    19801 aacaatctgt ttgaacgatt tgagacgatt gtttctgcag aaaatgttca acgagcaaaa
    19861 ccagacccag aaattttctt gttagctaat cagaagctag gtacagcgaa gaaagaaaca
    19921 ttgattttag aagattcaca aaatggtatt ttagcagctt ctgcggctga gatcccggta
    19981 gtcatggtac cagatctgct tccaccatcc caagaattga tcaaaaaaac agctggggtt
    20041 gtttcttctt tacatgaaat ccctgcattg ttaaaataaa aatccatctc ttttcgtatc
    20101 ttattttaga taagatagaa aggagatgtt tttttgggaa aacgattgat caaagaagta
    20161 cctactagct ctttaccaag ggaacgtatg gaaatttatg gcgcggaagc tttatcggat
    20221 caggagcttt tggcaatctt actgcgtacc ggtcaacacc cttatagtgt gatgtcgatt
    20281 gctggaaatc tgttaaaaac gtttggagga ctggcctctt tacgacaggc tactttgcat
    20341 gagttagaag agattcgagg gataggacgc gtgaaagcaa tcgaaatcaa agccttgatc
    20401 gaattaggtc gacgaattca gacggatcat gaaagagcgg ctccaccggt tcgtaccagc
    20461 tacgaattgg cccagcaatt gattctggaa atgaaagatc acaaacaaga acatttggtt
    20521 tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa aaacagtgtt catcggttcg
    20581 ctgaatcagt cagtcgctca tcctagagaa attttccatt atgctgtacg ttattgtgca
    20641 gcaaggatcg ttttagcgca taatcatcct tccggaatat ataagttagt acacataaat
    20701 tatataagga aatttactgt tatattgcca tctggaaata ctattatgtt atcgataatt
    20761 gaacgccata atgcattttt ttcttcttcc gaagattctt tataaatttc atcgaattct
    20821 tttgatagaa taaattcgac attttttata tctattttag ctggctctac ttcaatttca
    20881 tttaattctt tcattaaagc ttctcgatct tttttgtatt cctctaagtc tataacttca
    20941 ttcaagtagg ctttcttcaa tctatctaat ttattctcaa tatttttctt actatttttc
    21001 tttttaataa tctttggttg tttttttgaa tagtttattt gtatttgttc aaatttttgt
    21061 ttagtagctt caaaaatata acgttctaaa tttttttcgt aaaaagcgcg cttatttgtg
    21121 caacgtaatt tattatttct tcgttttaca catctataac aagtcctttc gtatatagat
    21181 tctgtaccgt cttttttctt atatcttgct ttaatagttt gaccagctac tgatccctga
    21241 cagtcagaac attttaataa acctttaaaa atgtaatcac gttttgcatt tgtttttaaa
    21301 tttttaggta aggctttttg aacagcataa aaaagttttt tatcaataat aggaggacag
    21361 taatttttat tatttcttaa ttcaccaatg tattttttgt tcgtcaacat atttttaaca
    21421 ctttgataat ctctaacgat tccatactga gagcctaaat aataaacagt ttttcttaaa
    21481 ctaccactag aaagaaagta gttgaatata tctatcacga taggagcatc atcatttatt
    21541 actaatttct tattttctat agagtagcct aacggagttt tcccgcttac tacttcacct
    21601 tgtgcaattt tatttgccat aacagctttg atgcgttctg aatcaatttg ggcttccaat
    21661 tcagcaaaac tcattacttg tgcaatgaaa gttctgccat acgctgtagt tgtatcataa
    21721 tattgttgag aaacagcatt ccaagaaaca ttgtgttttt ctaaaatttc ttgagtgttt
    21781 aaataatgtc gtagatttct aaaccatcta tctaattttg taaataaaat tagatctatt
    21841 ttattttctt ttacatcttg taatagtttt tgaaattcat cacgatttat tttttgacca
    21901 gaaataccac cgtctacata ttcattaact actttcaaat ccttgtgttg ttcgatatat
    21961 tcatagaggg tttctttttg ttctctaaga ctatctccat gtttggcttg ttgttcagtt
    22021 gatactctca tatataatgc tactcgtttc atgttatctc ctttcgaatg tatgttctta
    22081 tcgttgtaaa agaaaagccc gaaggctaat ctttttacta cacatctgtt aattctaatg
    22141 atcttctgta ttgttcagct tgagctagtt tagtaaaaga tacagttccg ttataatttt
    22201 ctaaaacaac tttttcaatt tcatcaagag atactttaaa gaattctttt cgttgattaa
    22261 ctttattgac ttcgtttttt ctaaaatgcg aatgtagttg attttctaat gttggtgcat
    22321 cttctgaaaa tatcattgca tgaacatcaa attcaaaagg tacagaagcg ctactaagtt
    22381 ccttaattct atccataggt tctaaccgtc tagtcattcc tattttatag acatcttcac
    22441 cgaaagatcc gatattactg atgacataaa catagccagc tctagtatta agttctcttt
    22501 gcaatacatc ttctttgaca gtttctagtt ctcttaattt ctcttccagt tctttaattt
    22561 tatcagcata gagttctttt tcaacatcag cactagcttt ttgcatgtat gccattaact
    22621 tagttatctc tgagttaaac tgtcgttctt ctttatcaat gcgtttcttt tcacgttcta
    22681 tttcacgtct taccttttct tcttcaatca tttgttcttt tattgctttt tgctgttctt
    22741 tttcatcgtt aactttaact atgtatgaat agttgagttc taattcttga agttttaatt
    22801 caagtaattc ttttttgaat tctgcttcat cgtttttaaa aagcttgttt attttatcaa
    22861 aagttcttat aattttttct ctagttgaat ctacgttaga aatagtaagt ttattgagaa
    22921 gtccagttat ttctgattct aatggtataa gcattttctt tttaatatta ttagcttctc
    22981 tattattcaa ataagaagga atattaattg caccgtctaa aataaaatcc ttttctttaa
    23041 tctttaataa agaaagtttg ttttttattt cggatgaaga agtttcatct atattcggaa
    23101 taattactga tttatagata gtgaccagag atgtgtcata tttttgatta atttcatcgt
    23161 ctaaccgctg gctttcagca ttaagaatat caattttgtt ttctagcgtt gacaagtttt
    23221 tattcaattt acttatgttt ttctcttttt cagatataaa cgtttcccta gcatttaatt
    23281 cttgagaata ttcctttacc ttactctcta aggcagaagt tttatctttt aattttttag
    23341 cttcagataa tttgctacta cccataatta ttaaaactat tccaactaaa aacaatagta
    23401 ctcccattca aaacgcctcg cttcttttat aaaataattg tcaaaatcat ataaaccctt
    23461 accgaagttg acggctccgg catgggaatt tttttaaaat acaacttttc cgataattct
    23521 aatctgttct ggcgatacaa ttctatcttc gtataagtcg tttatagaac gtaaaatgat
    23581 tgtttgattt tcgtaatctt tatatatctc tttacatgta actccgtcac cacctaattc
    23641 cacaatagca atttccccat cttctacgtc cggttgttct ttaacgaata cgaattgtcc
    23701 attcctgata acaggttcca ttgaatcgcc tataataggt actgcgaagt cagcagcact
    23761 tggaactctc tcaaattctt cctcttcgac aaccgtatca ccgtaagtaa gttctgttgg
    23821 attggcagcc gaagccgaat tgtgaacagt tgggattttt tcttttttag gaaaatctag
    23881 gacattttct tgtttttgtt cttctaatcg attacttgca aattcatagg tagcaacttt
    23941 attttcgtcg ttaagctgat tatatatagg aaggatatta tatatctgat tagatataga
    24001 taaatcaata ttcatcaaat catctatatc aacattgaat atcttagcta tctcatttaa
    24061 ggtttttaat tttggtgtat attttccttt ttcccattcg cttattgagg atgaactttt
    24121 tcttcctagt ttttcggcta gttcttgttg atcaatatta tacttttctc taagaaactt
    24181 tagattttca gcgaacatag taacacctcc ttgagttaat tgtaacaccg tttcggaaaa
    24241 aatgtaacag gtttcttaga aaatatttta gtgtttttaa agaagtattt acgcaaaata
    24301 gaaatcgatt tcaggaaaac tgaaatatgc acttgacttc ggaaaaaccg aagtatataa
    24361 tttagtcaga aagttaaaga gaggaggcga ataaaatatg gataccgcga agaaagaaaa
    24421 atatacattg agacaattaa gagctttaaa gggttattca aaagaagaac tgtcaaggaa
    24481 aagcaaagtg acatcaagaa caatatttat ttacgaaaac gatgtagata aaatgaggaa
    24541 cggaaagtac gccactctag aaaaaattgc taaggcattg ggtgttagag tttccgatat
    24601 ttttttagac cctgattcgg aaaaaccgaa atcaataaca ggtgaaacaa aacaagtcag
    24661 ctaggaggtg tgaatagtgg aagagaagaa tataaaagta ccgactcttg aagaatatac
    24721 aaaaattgtt gtcgaaacag acgagcagaa cccgaaaaca atcgcagtta ttacggcgaa
    24781 tgatattgaa tcatgcgaag gttttcgagt tcgaatgacc cctagatatg attaatgttc
    24841 tttatcacgt ggaggtatag gatcgtttcc aaaactatct tttgattgta tttgtccatt
    24901 ctttttttgg acaataaact ctgattgctg ttttttagaa atctttttac catactcaac
    24961 agcatctgat ttattatcaa atagttttgt atcttcggaa ttaccttcac cacgtacagc
    25021 ccatttgcca tttctaggag atacccattg atttttaccc ataacaattc acctcgcttt
    25081 caagttaatt ctattaagag gtgaaaagaa aacaaactga tggaggtgag attgtgagta
    25141 acaagccaaa aatcactttg aatggcacac ctaatcttca aagattagca gatgaaatgg
    25201 ctagaatacg ttctagacat tggggagtta ctgtggtggc aaccataatt gaacaaaaag
    25261 aaaagcccac acagccggca agcaagtagt gggcaccata gaacaataat attatatcac
    25321 acactcgcca cttccgaaaa gaggagttgc tgctctcctt tcaagtttgc caaagtccac
    25381 gtttcttcat tttggcaact cctcttcttg gaggtggtga cggcgagaga cgaaggaggg
    25441 atgacatgaa ggaagaatca aaaataggga ttttgaatga gaacaattac acaagattaa
    25501 ttattgaaac agaagaaggg gaaaaagtag cagaagttac attgaccgat gcaactcctg
    25561 ctgacggtta tcgtattcga ttaactccta aatatgatta accttttggt gggtgtggat
    25621 cgtttccgtg actatcacgg ctttgaattt ttccatctct gccatgaata aatagctcag
    25681 atccttgatt tttagaaatc tctctagcga tttttactgc ttctgatttt gtattagtat
    25741 gtgcagtcgc tttagaattt ccagcacctt tgacattcca accaccattg gaattaggta
    25801 caacatgttg attttttccc atagttttca cctccatttc tatagaaata ttttatcaaa
    25861 tagaaatgga gaaattcaat aaacgaaagg agggatcaaa tgacattaca agagcatcaa
    25921 cacttgatgc gaaaactaaa tcaggaatac cacgaggaaa tgaaacctag attgctaggg
    25981 gaacaatggc gtgaacgcca gaagaagtgg ttagaaataa aaaagtgact cagccgtcca
    26041 aagcaatgag tcacaaacca aaaattatac ctaaggagat tttatcacat gaataagaaa
    26101 attgaaaatc ttatcgaaga attgaaacgt gaatgccaaa agcaaggtgt ttctattatt
    26161 tgtacagccc aaaaagaagg ggaacttaaa agtctcgttt atggtgagac aacagaaatt
    26221 ttactttgtc ttgctatgca agaagaacat ttagatgaaa atctcccatt gtcagcacat
    26281 attatgcgta gaattgctgt ggatgcttac gaacaagcga aaaatgaaga agaaaatcaa
    26341 ccttcaaatc atacttttgt tattaataac aaggaagatt tagctgatgt gatgactcgt
    26401 attctcaagg gggaatttca atgatgaatg aaaaaacaat tgatctactc attattttat
    26461 ttttcacgtt agtgattgta gcgaaaagtt atgtaatctt tggcttgtta ttcgcaatta
    26521 ccatgcttgt gctttgcgtg ttagcaagca gaaaagaggt taaacatgaa cgagttagca
    26581 aatcttgaca actatttaac tgatcctgat tatgctaaac caccatatga agcgccaatt
    26641 gatgaggagg atgaagatga gtaaatctac cttagaaatg agccatcaag aatggctcga
    26701 agaccgcaaa agaggtattg gtggctcaga tgttgcaacc gtacttggat taaacaaata
    26761 caaatctcct tatcaattgt ggcttgagaa aacgggtcaa attgaattga aagatttaga
    26821 aagcgaacca gcttattggg gtaatgtttt agaagaagtg gttgctaaag agtttcagga
    26881 acgtacaggc aaaaaagtac gcagaagaaa ccaagtattt gaacatccat tacatccatt
    26941 tttaagagca aatattgatc gggaagtagt gggagaaaat gccattctgg aatgtaaaac
    27001 agccaatcaa tttctcggaa aagagtggga aggtgaagag gtaccgctta gctatctctg
    27061 tcaagttcag cattacatga acgttttaaa caaagactat tgttatatcg ctgttttgat
    27121 cggtggacaa aaattcattt ggaagcggat tgaacgagat caagagctga tcgatacaat
    27181 cactgaacaa ttagtagagt tttgggaaac gaacgttctt ggaggtatcg agcctgtaat
    27241 tgacggaagt ggagcgactg ctgacttctt aaaagaaaaa tatgcagatg tagaagaaaa
    27301 tcaaacagct ctaccatcac gttttgatga acttatcgag caaaaaagag aactcaagcg
    27361 gacgaaaaaa gaaattgaat catctattcg tcaagtagac aacgagatca tcagtgagct
    27421 aggtaaacgt gaagccagta tcggtatcac acaaagaaac attatcagct ggaaacttgt
    27481 tcgtacaaga cggatgaaca cgaagaaact agcagagaaa tatccagatg tcgcaaatga
    27541 tgaagagatt tataacgtta ctgaatcaag aaggctaacc gaaaaggaga tcaaataata
    27601 tggcaacaaa tgaatcgtta aaaaatcaat tggcagaaaa gccacagaaa caagttgcac
    27661 caggacagtt agggcttaaa gctctaatga atacaccaac aatgagaaag aaatttgaag
    27721 aagtacttca tgacaatgct aatgctttta tgtcgaatgt tatgactctt gtatctaatg
    27781 acagttatct tgcagatagt gaaccgatgt ctatcatgag tggtgcgtta actgctgcaa
    27841 cattaaatct tgggctagat aagaatttag gttatgcata tttagttcca ttcaatagta
    27901 aaaacaagca aacaggaaaa tgggaaaaga aagctcaatt catgcttggc tataaaggat
    27961 atatccaatt agcccaacga tcaggtaaat acaaagcatt aaatgtgatc gaagtttacg
    28021 aaggagaact aaaaagctgg aaccgactga cagaagagtt tgagtttgat ccaaatggta
    28081 gaacgtctga tgaagtcatt ggatatgttg gctatttcga gttactgaat ggattcaaaa
    28141 aaactgtcta ttggaccaaa caagaaatcg aagctcatcg gattgctaac aataaagatc
    28201 gcgataagac aaagttaagt ggtgtgtggg catctgatta caatgcaatg gcacgaaaaa
    28261 ctgttttgag aaatcttctt tctaaatggg gaatcttgtc catcgaaatg caagaagcca
    28321 ccacatcgga tgagagagtc caaagggttc aagaagacgg cagcattatt gctgaaacag
    28381 aagttgaaga agatattcct gaaagaaaag aagcagaggt tatatctgaa gaaaatgaag
    28441 atgtacaaac tggattattt gatgcatcta atccgccgtt aaacaaataa tgagggagct
    28501 ttctcccttg cttttctaga ggagaaatac gaatgaacac aggatatgtc aaattacatc
    28561 gaaaagtgat gaattcattc gtttggacca atccttatat gtataaatta tggagcttgt
    28621 gtttgatgaa agcgagtcat gagaatcgca agatactttt taatggaaaa gagatacaag
    28681 tgaacagcgg agaattcgtc acagggcgcg atgctatcac atctgagatg aacgaaggcg
    28741 tgaaacgtga acatcaagtg aacagcggtt ctgtatggag atggctaaaa caatttgaaa
    28801 aaaacggaat gttgaacatc aaatcaacta cgaaatacag cgttatatca ataaaaaact
    28861 ggtctttgta ccaaagcagt gaacaacaaa tgaacatcaa acgcacaaca agtgaacaac
    28921 aagtgcacac aaacaagaat gaaaagaatt ataagaatga aaagaataat aaaacatcat
    28981 cgtcgcaacc acgcaaaaag cgtgtttacg acaccgactc agtttactac attctcgcgg
    29041 aggagttatt caaacagatt tgtcagaatc aggaaatcaa aaagccgaat ctgcaaagtt
    29101 gggcagataa cattcggaaa atgatcgaga tcgacaagcg gaccgaaaac caggtacggg
    29161 gaatgattga atggagtcag cacaatgtgt tttgggcatc gaatatttta tctgctaaaa
    29221 aattgcgaga aaaatacgac acaatggcag cgcaagcaaa tcgtgattat aaaacaaaac
    29281 aaactaaaac gcttgaatac gagaaattta gcacagatga gttgcctatt tgagaggagg
    29341 cgtaggcatg gaaactgttg gggaaatcat ggaaaagctg atacagaaag tgcttgtcca
    29401 acgtggcgaa tgtcctgaat gcggacagcc tttgtatgga tggcgtacga agaaccctga
    29461 tggctcagaa cgttgtaagc caacctgtat gcaatgtggg tataaagcat tgcgagttca
    29521 ggaagactta caaacagaac gaatttacaa cgagagcctg aaagcaagag caatcaattt
    29581 tttcaaaggt ggttctgttg tgcctaatca agcgttgttt gattgcacat tgcagaatta
    29641 tcaaattgtc gatcaagaaa caagacaagc ggttgaagta accaaacgct ttgttaattc
    29701 agtcttgtta ggaaatccaa gtcaccttgt tttaactgga aaacaaggaa caggtaaaag
    29761 tcacctagcg atggcagcgg cttgggaagt cttgaagcga tcaaactacg ataaaaaaat
    29821 cttatttatc gggttacagg aaatgctgga tcaaatcaaa ttttcgtaca acaatcctga
    29881 actcagaaaa acgattgagg gatcgttgat tgcagatatc aaaacagcgg atttagtcat
    29941 cattgatgat atcggttcag aactaggaaa agatgcatca gatagtcgag cgtttggcat
    30001 aaacacgcta aattcgttct tggatgcacg acagaaccta gcaacgatta tcacaacgaa
    30061 cttgcttggt gaagaactga aaaaagctta cggtacgaga acaatatcaa gaatgtttgt
    30121 caactctgat ggatttacga tggtattttc tcaaacagca gacaagcgca taaaaccagt
    30181 gaaaggtagt atcgcatgaa taaataccgt aataaaaaaa ctgttcatcg aggtatcaag
    30241 tttgattcta tcgcggaagc agagtattac gatctagcct tgtggcaagc tgaagcgaat
    30301 ggttggaaag tgaagctcca ggaaaggttt gagctgatgc cgaagtttga actagagggc
    30361 aagaagtatc gcaagatcga gtatattccc gacttcacat tttacaaaag cggcaagctg
    30421 gtcaaagtcg tagatgttaa ggggatgcag acaaaagact ttaagatcaa ggcaaagttg
    30481 ttctgtcatc aatatcaagt gccgttgata ttagccaaaa aatatcggaa tacgttcaag
    30541 gaagagcgtt tttaacgagg tggtccatca tgacaacaga agaagtgatt caaatgcgaa
    30601 ttcgaagcct tcggcgtgag attgacgatc tggaacgaac aaaggcagtg atggtcaatg
    30661 aaacggctag aaaggcaatc gatttgcaca tagagaattt aagaagggaa atccgtagat
    30721 tggaggaatg agcgtggata aggaagcggc ttggcgaaaa ttaatgttgc tgattcaaga
    30781 tgagaactgg caagaagatg aagcagtggt tgctgaagtt cagcgtctag gaaagattgc
    30841 taacggacgt atacgaaaaa agccagacaa aagaaaacag cgcaaaggga aaatcgtcgt
    30901 tgttttacac gaaggcaaaa ttttgatgca aggaacagct agtgagctgt ctgcagaaac
    30961 tggatatacg cgtgggacta ttcgaacgta cgcttggcga aatcacaccg atcgaaaagg
    31021 gcacgaatat aagtatttgg aggaagaaaa atgaacgaaa acaaattaat caaattgggt
    31081 gtagcaggag cagtaatcgt aggtattgga gttatcggag gatttaagtt cttcgaaaaa
    31141 atcgataatg gatatgtggg tgtgcgctat tcaatgaacg gcggtatcaa agatgaagca
    31201 ctgacgcaag gtgtgaaatt tgtagggatt gacaaagtga tccaatatcc aattcgcttg
    31261 caaactatcc aatcaaaaaa tatttcagta tctacaagcg acggcaaaaa gacaacgatt
    31321 gatatcaaat atgactacaa agttgattca actaaagcag caaaaatgta caaggaattt
    31381 gggaatatca cttcggaaga tatcgaaagt ggatggttaa aatctaagct tcaaaaggtc
    31441 gctcgtgaag tttatgcgaa atatagtctg cttgatgtcc tttcaggaga ttcctctaaa
    31501 gttgaagctg aggtattaac gaactttgct aaatcagttg aatctaaagg gtttgaagtc
    31561 gaagacgtaa cacttggtgt tccagatgtc gataaagaaa cacaaaaatc aatcgatgcg
    31621 atcattcgag ctggtcaaga aaatgaaaaa gcgaagctag acgcagaaac tgcaaaaact
    31681 caagctgata gtgaagctta caagaaaaca aaagctgcag aagcagaggc agaatctaat
    31741 cgcaaagtcg ccgaatcagt aacagacaat ttgattcgtt atgaagaagc tcaagctcgc
    31801 aaaaagcatg gatgggtaac agtaaatgga gcagatactg tagttacgga tgaagcaggc
    31861 aaataatatg ggattcttta tggctaaaat tctcttgttc ttaggtttag taggagcagc
    31921 atatctcgtg tatgcgctcc tttcccaaac tgatgacaaa gaagatgaca acaacgatga
    31981 aatgaaattt taggaggaga aataatggac gaactaatca caaaagtaga gcagtgggct
    32041 aaagacaagg gactggatca agcagatcca aaagcacagt ttttgaaagt agctgaggaa
    32101 ttcggggaaa tagcttcggc gatggcaaga agtaatgatg aactatttaa agatagcgta
    32161 ggagacgtta tcgtcacgct gattatcctt tccatgcaaa aagggacaaa cgtacaagag
    32221 tgtttagaaa tggcatacaa cgaaatcaaa ggacgcacag ggaaaatggt agatggtgta
    32281 ttcgtgaagt cgagtgattt ggaggatgtg aaatgaaata cgaaatacca ctaagtgaag
    32341 cgggcattca agcaattatc aatggtcggg aggttaacat agaacttcct gatggtactg
    32401 aattagtcat cagacaaagt tatttgaaag atatggcagc tccagtatta attgatcgtt
    32461 ttaacgtgac tgattctgtg gtagagaacc acttaaaaga atttcgatca agtatagacg
    32521 acactttcag attagggagt tgattgacaa tgaacaacag acatcgcaga ataacaaaac
    32581 taagaaaaca ggaactgaat gtactaaaga caaagtttga aaaagaatat ggaatttcag
    32641 cagaagaaac atataaagtg gcaagtcagt ttgttgctga tgcaagtgat gctattcgta
    32701 agtttgggat ttcgatatta aatgatgatc gtaaatggga ggaaatgaga tgaaactaaa
    32761 agacggattt tacgctagta gtcacggcat cggcggttta atgctagata tgccgacaaa
    32821 gaaccctaaa acacgtaaga aaccaaaagt caaagtcggt gacatggttc gctgtgaagc
    32881 agaagagttc atttatccgt ttcgtggata tgtagaacac gtctataatc actcagcgat
    32941 cattcgtatt gaaaacacaa tggaatgcga taagtggtta gcgaaaagca aagagaattt
    33001 agctgtagcg agattggtgg atatggaggt tataaacaat gaagtttaaa atctttgaag
    33061 aggacactcg ttataaatta gaaaaagaat taaacgattt tgcgaaaaac aatgagattc
    33121 agcatatatc tttagcaact tctaagagag gttatgcaaa ttactatgca gctgttgtga
    33181 gctatgtaag tcgagaagtg taactcggca aataaaaaaa gccggatcgc tccgactgat
    33241 tcaataaatc caacacattt attatatcac ataaaggagc ggtttgactt gatgcaattg
    33301 ttacgagagg tagatttcaa acagacaaga tgtaatgcga gagatgtgct gaagaacttt
    33361 cggcgtttgg agcggatggc aggtcgctct ttgatagata ttaagtcgcc gattattacg
    33421 gatatgccga aggcaccgaa gcacggcaat aaggcagaag acgcgatcat tcaaatgatg
    33481 gatatagaag cggagagaga cgcgattcta gtggctttga tggctcttag tctgattagt
    33541 cgtcagatac tctactacag cttctgtgtg ccagacagct tctcaaacta cagaattagc
    33601 cgtgaagtgg gttattcaga aagaagtata caacggatga aatcggaagc tctaatagag
    33661 tttgcagaag catataaaca cggaagaata attgcttata aataggggga ccatataatg
    33721 tggaaagatt atgtatcgtt gaaagagttg aaaaaagatc ttgttttcaa aagaattgta
    33781 gaatggtcag agagtgaatt aattttagaa gatggaacca aaatggaagt tgtatgtagc
    33841 gaatcagatt gctgcgcatg ggccgaaggt gaattcaaaa atgtaaagct tgatgcagtg
    33901 attacagata taaagatttt tgataaaggt aaccgtctct ataatggtga cggacatacc
    33961 tcttatgctg aagtcgttgt ttatcataat cgtaatgaga tcgctaaagc agaatgcaca
    34021 gcgaatgatg ggaatggcgg ctactattat agtgtttgtg ctttaaaggt caaagacaaa
    34081 ctttgtatag tgactgacgc ataaaaaaat ggcggttttt tggcggaatg atggcggttt
    34141 ttagccattt atcagtgata ttatggtagt gtcgaaagat tagtgatagg tctgagacaa
    34201 aataataata aaaggaacat cgttttatta ttgtttcaca attaagcttc gatagacagc
    34261 agcggaaata ttaagaataa ggatgtgaat tttaactcct tctaaattgt tcttattatc
    34321 tatcatccgt tgctgtctat tgttacatac agatcgctta ggcggtcttt ttattttggc
    34381 cgaaaaccta cattttcgat ggccgattat tggaggagga atagcatgtt caaactatct
    34441 gaaatcatta agaagtccga cgttgagaaa ttagagatgt taaaaaagaa gttgaagaaa
    34501 tagcagtctc ttcgtgaggc tgttttattt tgctcacaaa aatagaccac tatcgggtaa
    34561 tagtggtcag gaattaaatg aaaaagatgt tagggttgtt agctaagtat aacatcataa
    34621 cgcttacaaa acaatgcaag aaggataaat tattatgaga acttactggt atgtgtcatt
    34681 aaacaataaa tatccgaagc caatgaaagg acagcatagg cgtgtagtca tgtctgttca
    34741 aatgaaggcg aagtattcga ttgtagaaat gatcagagag gcaacgccag tagagattga
    34801 ttattgcaag ctagtctatt gtgggtgcgg ccgttggaaa gaggatcatg tacaaaaaaa
    34861 tatcagcaag tacatataga gaggcggtga ttaaggatgg aaaaaagcga tacgaaagcg
    34921 aacagataca aacctactgc tgcagagaaa aaactcttgg aagtattgat aaatccagat
    34981 aacttaggca aaccggtgca agagttgtgt tcactggcga aaataggtag gaccaaatat
    35041 tacgacgcca tgagcaaaga tggctttgtt gatctagtta acgaaacaac aatggatctg
    35101 atcaaaggaa aagcttctga tgtccttaat gccacttaca agtatgcatt gactgaaaaa
    35161 ggtcatcagg ataggaaaat gattctgact attgctggaa tctatgcaga caaacaagaa
    35221 ctcaaacatt ctggcggcgt cgatatccga aaacagtatg agaaaatgtc cgatgaagaa
    35281 ttagaagagt tggtgaaacg gtatgaaaaa atcaacgact cttaatcgtg ttgagtatgc
    35341 cgttgttcaa agagagctag ccattcgaaa agctaggaaa agtttttggc tattctgcca
    35401 gcttctttat ccagagtttt acaaagatga tcggttgtat ttgaaagatt tatgtcatac
    35461 gctacaagat ttttacgaag ataaaatcga caaaaaaatt ttggttatta acatgccgcc
    35521 tcgacatggg aagactttta cagcgcggct attcgtttta tggatgtttg gacaaaatcc
    35581 aaagacgaaa attattaccg gatcttataa ccaaatcctg tcatctttat ttgcgcaaca
    35641 aacacgtgat ggaatcatgg ttgaaaacga aaatgttaag gctgaatact ttaaagatat
    35701 ttttccagag gtgcaaatca aatatggaga tgctgcaaag ggtttctggt ctttagatgg
    35761 ttcagaagaa aagaattatt tagcgacttc tcctggtgga acatccactg gtattggcgc
    35821 gaattatgta attgttgatg acatcattaa aaccgcagaa gaagcctata acgagcgtgt
    35881 tttagattct cactgggaat ggtataacaa cacgttggcc caacgaatgg aacggccacg
    35941 taaacagata ttgattatga cacgttggtc aagtaatgat ttagccggaa aaatgttgac
    36001 gagacgaaaa aataatgttc atcagatctg ttataaagca gtacaagaag acggctcgat
    36061 gttgtgcaac gagattatga cccacgatga gtacttagat gtggtacaag aaatgaatgt
    36121 agatattgca gaagccaact atcagcaaga accaattgac caaaaaggca ggctatatca
    36181 gaagtttctt acttatgata cgttgcctga taacattatc aaaatatgga actacaccga
    36241 caccgccgac aagggtgccg attactttgc gtctcctgtt tttgctgaga cgtctgatca
    36301 tgatgcttat attatcgatg tcatgtatac aaaagagccg atggaaacaa ctgaaatagc
    36361 ccacgctaat atgattattc gcaatcgagt taataaggta cggattgaag gaaacaatgg
    36421 cgggcgtgga ttcagaagaa attcagaaag aattacaaaa gagcgaggct atcgaggtgc
    36481 agtatttgaa gactttcatc aatcggataa taaactgtct agaatactgg cgaatagtgc
    36541 ttgggtggaa aatcatgttt actatccaga tgattgggcg acacgttggc cggactttta
    36601 tgaggctatg gttagttatc aacgtgaagg taagaacgct catgatgatg ctccggatgc
    36661 agttacagga attgcagaaa cgattataga agcagatgac ttcgagttta ttgcttatta
    36721 ggaggtgggt ctttgtttta ttctggaatc acattgaaaa aatacaaacg tttaagaacg
    36781 aaatattcaa cgcaaatcga agaaggatta ttcgatccta acgcttttat ggaagatatg
    36841 aaaccctttt tcgatgatcg agaaagaaag tatcttgctt atactagcga gaaaaacgag
    36901 atcgacagtc gtgagaaacc aaaaacaaaa atcattaagg tcaataacaa gattcatgcg
    36961 ggaatgtatt cagtggtcgt tgatcaagca gttaaccatt tcacaggaat accaattaaa
    37021 tgggattatg atgtttcgga acagaaaagg acattcattc aacgaatgag agacaaatta
    37081 ctgggtaatg atatcagcgc cccttctacc ccagaagaat ttgaaacact cacgagacaa
    37141 ttaagtacta tgcggtttgg aatgttagac cccgatactg caacatttca aggagcgaca
    37201 gggcttgctt tcagattact ggagcctgtt gagacaaatg atggttggga actaagagca
    37261 agcaacattg agccgtggaa agctgaaaag tacgaaaacg gcgcagtgta cattaaagag
    37321 aaatacgatc catatcaaaa gaagttttat gaagagatga aggttgtcac gccgaaatca
    37381 atatttactt atgctcgata tactgattac cctggcacgg tacaaggagc atttaaaacg
    37441 ctgggtaatg ttcctaatcc tttaggcgtt atcaatctta cggagtttaa aaacaataca
    37501 aaccgttact gtgactttga agttgcagag gagattagtg atgctattga tcgtgtttta
    37561 tctgatcagc agaacgagat tgaacaattc aagttagctt atatgctgat cactggggca
    37621 gatttgtccg aggataaagc caagaagatg atggagcaac tagggatcat caatctgaaa
    37681 gaccctaatg cgaaagccgg ctacgtgaca aaggatctac aaaaggattt caacgagtat
    37741 cattttgatc ttcttaaaaa gcaattctac acggtgtgta aagcaattga tttcaatgac
    37801 gaagtcttta agtcgaatag ttctggggaa gcccgaaagt ggcaaatcat tagtttagaa
    37861 gctaagacaa ataccaaaga acagtacttt cgagaaggat tgaaagagtg tgccgaggtt
    37921 atggctgctt atttggattt tgccgagaaa gttacaattg atccggaaaa gatcattttc
    37981 accttctctc gttcgcttcc aacagattta agctacctag ctgaggcatt gcctaagttg
    38041 gcaccatacg tttctaagag gacgattcaa agtcagatcc cgttcgtcac agatgttgat
    38101 tatgaaaacg aaatgattga cgtcgaaagc agacaatctt acccagacgg cgagtatgga
    38161 ggtggcatcg ttgagtcaaa tagaaacgaa gtactggacc aaacgtcgag aactggaaga
    38221 tttagcaaga ctcaaaatgg aaaatcaaac gctaaagaaa ctaagtagtg tctttcctga
    38281 tgcgttgaaa gaaattcaag cggagttatt atcccaagct gatttacacg atattaccta
    38341 tgctgagatg atggaatttt atagtacaag tgatcagaaa aaatatcgtg aatacgttga
    38401 aaagaactac aaatcactga agatgtatga tgcaaaatac aaagagttca tcgaagaata
    38461 ctttccttct ttcgactacg ccaaagtgaa tcggctgctt caaatgaggt cagatatttt
    38521 tcgaattctt gcagagagtg caatagatgc agatgtgaat aaatattttt cggatcggtt
    38581 agaagatatc ttgcaacgtt cgtatgtatc aaacgcaaac gtatttgccc agattttgaa
    38641 cgtagatttg ccgaattact tatcaaagga agaacttgaa cgttacctga actatccttg
    38701 gtcaggtaag acattctcgc gtcgtttatg gggcaatatt tcatctctag aacaaaagct
    38761 atctaacgcc attacaacta gtgtagcaag tggcgaagga gttctcgtgg cattacgaac
    38821 aatgcgagaa gacccagaaa tatgcgatat gttcaaaagg gaggaatcga agtacaacaa
    38881 ggcgatcgaa aatcttgtga gaacagaata cgctaaattc gctcaagatg gtattgagaa
    38941 atcttatatt gaaactggcg tagacgaata caatgtctta actgcaaaag atgaaaaggt
    39001 atgttcaata tgcggtggca aagcaaagaa caacccatac aagttgagtg aagcgatcat
    39061 tggtgagaac cgtgcgcctt ttcatggccg atgcagatgt acagatgttc ctaatatgcc
    39121 gaaattagga aaagatattg acgaagagta tgagcgttta tttggcgatt tattagatga
    39181 gtttgcacat gattcttttg gaattaattt gaaacggagg aagtagaatg aaagattttt
    39241 ttgaagcagt actaacaatt aatgtaaatg ctgatattgc agaagcctac aaaacagcta
    39301 ttgagtctga gaaccatcct aatggcttga gagaccattg gaatggcaat tatgcctacg
    39361 tggttattgg cgatcaaact gttaattatc aagataatac tccagttgat aagaataccg
    39421 ttaatttaac gattcaatta ttatctcatt cattaccaaa tttaaaagaa acagttgatt
    39481 ggtatgaaaa tatgggatgt attgttgtta gaactgacta caaagaagga aagtctagta
    39541 attaggcttt tttattttgt ccgaaatgac gttaaactag cgcaatactg ggcttggttg
    39601 aatggtgggg cgcaactatt aaaactcaaa gcaatgcggg gcgtgaaaac gaatcgtggg
    39661 gcgaaaggag aatgattatg aaacacaaat cattaatgcc aatgaatttg caatactttg
    39721 ccgaaggtga cgatcaaaag ttttcttttg atgacttcaa atcttttgtg gaatccaatg
    39781 aagaagctca aaaatttatt cagtcacaat ctcaaagtgt tgccgacaaa caattggaag
    39841 cttggaaaca aaataactta gataaaatta aacaggatac catcaaggaa tatgaggaat
    39901 ctaagaaaaa caagtcacct gagcaaattc aactggaaaa actacaagct gaatttgaag
    39961 cagaaaaagc gttgcgtgtg acaagtgata ataaagcatt tgttgcagaa caaattgctg
    40021 gattagaact agatggagag ttaaaagagt ctatttctca atttatgcta aataatcttg
    40081 ttagttcgga tacagatttc actaagaatg ctgttgaagg ttttacaagt gttttgaatg
    40141 caattaatga gaaacatgca gatgcattaa aagaactaca aatgaagtct gcatttggtg
    40201 gaactcaaca atcgaataac caggttcagc agaacaatga aacattaaca aatccagaag
    40261 aacaattagg acaaattctt caacaattta actaggagag tgaaaaatta tgaaaaaaac
    40321 atctttaaat aatttagagt atttggatat ttcaccagcg attaatgcta tgcaagtacc
    40381 aaatacacct tttttaagct atttacttgg tgctggaaaa acagagccag caaactcgac
    40441 agaaattaaa tggcgtgaat atgatatcaa caacgatgat tcttctgaaa aacttgaggg
    40501 cggagaatat ccagatgctg aatcaggtcg aacttggttt aacaactata ctgaaatttt
    40561 tagaaaatca acctctgtat ctggtacatt agatgctatt aatgtgaatg gagtcggaaa
    40621 tgaattaact aatcaagtag cactacgtgg tatggaaatg aaaattgatt tgaaccgaaa
    40681 attgattact ggtgtaaaag ctgatgaaaa tggttctaaa ggtcgtcgaa tgaatgggat
    40741 tttgaacttg atcaattcag caaataaggc agaaacagcc actgcgggtg cagtaacaag
    40801 aaaagatatc gatactttat ttaaattgat gtatgaaaaa ggttatatgg gagaaaaact
    40861 atgcttgatt tctccagata tgcaggagtt aatgactgat gagttagatg gaaaatcaac
    40921 aaaaattgtt cagttcgggg aaagagtaac ttttggattg caaattggaa atatcgtgtc
    40981 taattacggt acaggtattg ctctactaga accatcattg ccaaaaggaa caattgccgc
    41041 aatcgatact aattatgtga aactacgtcc attacgtgaa tggagagcag aagaacttgc
    41101 aaaaacaacg gattctagac gtatcggtct tgtaggtgaa tactctcttg aatacaatgc
    41161 ttcaaactct ggggcaattt taaatttaaa gtctgaataa aagggagtta gtactccctt
    41221 ttttgatagg aggaattaca gtggtaaaaa aagatgaaac taaaaaagat gaagtcgtga
    41281 aatatagagt aggtaaaact aaaaattttg ttgggtttgt tcatcctaaa actcgtagat
    41341 ttatcacagc agattcaaat aacgaattta tcatttctat agatgataaa gaagcaattg
    41401 caattttgga agatgcaatt gatgttaatg aaatttagga agtgatctga tggatgaatc
    41461 gctaaaaacg gaaatcattg agtctacaaa agaagatttt ccagatttga gtgaagaacg
    41521 cataactaat ttattagaaa taattttgct agaaattgaa tcatacaaca cttgtaaaaa
    41581 tgatatttca tgggaaaagt taaaaagcgt gattagtgaa gtgttgtata aaataataaa
    41641 aaatgaatca gaaaaaacag tatcttcagt tagacgtggc gatacaacga ttagttatgc
    41701 ttcaacaaca aatgatgtta gtgagttact tctaggctat ggtgatttga tacgaagagt
    41761 tattggttgt ggaggattgg agttttttta atgaatgaag cagatatttt agaaactact
    41821 tatgaagata gttgtattat tgaaagactg acggacattg aagattctaa tacaaatatt
    41881 actattcaag attacaaaaa agtatatgat aatcctattt cttgcgctct ttcacaaggt
    41941 caaatcgatg gactagcagt catagaagat ggagagatgg taaatgtttc aactgacaca
    42001 tataaattat ttgttcatcc taagattaaa ctaaaaaaag gagatcgaat aacaataact
    42061 caaaaggcca gtggcttaat tttttctcta tttgctacta agccttttta ctatcctagt
    42121 cattgtgaag tgaatttgat aggaagtgag aaaaatgggt aatctcaaat atgaatcaaa
    42181 tgcagaaaag atcattgaga attttaaaaa tatgactgta attgctcaaa aagaaggaat
    42241 atccttcgtt aacgattcaa tgaataaagt cgttagttta gctaaaccat taactcctgt
    42301 aaaatcaggt aatttaaggc gaggatatcg tgtagtaaaa gctagaaaac tatcaagcgg
    42361 tcgaattgtt ggagcagtta taaacaatga acattatttt aaatatgtag aagaaggtca
    42421 taggactaaa aatggtggct ttgtcaaagg gaaattcatg ttaactcgtg caacgaatct
    42481 tgcaaatatg tcttatattc ctcgaagatt taaacaaatg gcaataaaaa tcgttaagaa
    42541 aggaaagtaa catgaaagat gaaatcattg ctgcaatcag tagcaaatta aaagaaatct
    42601 atcctgatgg gacaatatat cttgattcag ttatgcagtc aactaaagat ttttatttcg
    42661 ttttatcagt aatggaatct ggaactgaaa atgtaggaat tgatattcaa aatgtttctt
    42721 tcttaattga tattgcattg attgataata aacctaatag aaatttaatt aatgaattag
    42781 tctcacgttg tgggactttt tttaatacga ttacaatcga tgagcaaata ttatttccaa
    42841 aagcctattt acctgatgaa gcagatggtg ttcaacatat tcgttttaca ttagaatttc
    42901 cacaatatat tgaatggagt gaaagataaa tgggagaaaa aagaagtaaa accggaatta
    42961 tttctgtcga aaaacctact tggtttcctt tggaagatga gacagggaat ttcccggtat
    43021 atggtactgc gttgccaatg ggaacagcag taagtatcaa accaacagct aattatgaaa
    43081 caacacaaga ttatggggat tcagtggttc aagatcaatt tacagctttt ggtggtgcag
    43141 aagttgaact ggaagcaaat ggatatactc ataaagtttt atctacaatt actggaggga
    43201 aaattgttaa aggtggtgcc ttgcgttctg gagaagatat tgcgcaagat ggtgcgtttg
    43261 catatagacg taaaaaatcg aatgggaaat accgttatac ggtcttttat aaaggacagt
    43321 ttgctctaga ttcagatgaa acgtcaacga ttgaaggaag taaagtaagt tttactcatc
    43381 caacttggaa gggttcattt gtagatgtac caggacttgg atatatgtat tcagttgatg
    43441 aagatgatga aggcgtggat aaagcaatga tcggaaattg gtttacaaaa gtagcaattc
    43501 caattgaaga agcagaactt tcaggaggta cagaataatg tcaaaatatc aaacaacgat
    43561 taaattaacg aaaaaagatg aagaaggtaa atatgagcaa gtacaattta aatctgctga
    43621 atttttacca ggaacagttg tagaagatgc tgcaggagtt atggaagaaa tgcaaacagc
    43681 gactgataaa caatcagtta aaaaagcttt aagtcgtgct tattcattta ttgcagatac
    43741 tttatttgag ggacaattta ctggtgaaga ttattgcaaa ggaattgatg ctcgtgagat
    43801 tgcctcattg acaggaaaat tattgaagtc tgttactgca ggttttgatg aaacttatac
    43861 agagacgaaa aaaaagtaag tgaggcgctc aagtcacctt catttaagta ttcgattact
    43921 taccgagaat tagatataaa gacgcaatta ctcgaagcag gttggacgtt accagaaatt
    43981 gaacgtactg acttggatga gttaatgcgt ctttttgctt ttagagatgc ggtaaaagag
    44041 catgaagatg ttgagtacta tgataatttc actcaatttt aggaggtgat actttgaata
    44101 acgatgacct aattctgaag atgatactag atgaatctgg ttttactgcc ggtatgaata
    44161 atgctgtcaa aaagttgaac tcttttgatg aaacaatcga aagaaaaagt agaaatggtg
    44221 gcagttcatt aggtagtatt tggaaaatat ttgctggaag ttttctagct agcggagtaa
    44281 ctagaatcgt aggagctggc tttgatctaa tcaagggttc cataagtgga gcggttgatc
    44341 gagtagatac gatgaataac gctctacgaa atttccaaaa tatgggattt agtaattcag
    44401 aaattatgaa gaatatcgga aagaatgggc ttttatctca aggtattcaa ggacttccta
    44461 ctgctttgaa tgatgcgata agtcatgttc aacttcttgc ttcttctaca ggtgatttaa
    44521 ctcgttcaac tcaaatattt aaagctttaa atgatggaat tcttggtttc ggtggttcaa
    44581 ctgatcaagt taatgaagct gttattcaat tatctcaaag tttctcaaac ggaaaagtag
    44641 acgcacaaac ttggaactca atgatcaacg ctcaacttgg acctactctt tctgctattg
    44701 ctaaaaagat gggaattaca atgggagatc tgaaagaagg tttatctcaa ggtaagattt
    44761 ctgttgaaga attccaaaat caattaatag aaatggatac caaaggtggc ggaggactta
    44821 aatcattaag tcaaatcgct aaagattcta ctaagggaat taaaacctct atacaaaatg
    44881 caaaaacagc tgttacacgt ggtgttggtg aggtaataga aggattaaat aaagcattag
    44941 tagattcaga tttaggtgga tttaagggga ttattgataa agttgccagt tccatggaat
    45001 cttttttgaa agtaattgct gcaaatattc ctagagcagt gtctttttta agtaatcttt
    45061 ttgatgcagt tcaaaaattt ggctctgcat tgaaattcat gatgccattt ctggttcctg
    45121 caactactgc ttttggcgca ttaatgtttc aacttaaagg aataccaaca attataaaaa
    45181 gcttcaataa ttttaagaat gccataatcg gtgttggaaa ttcactaaag attatggggg
    45241 ctatagccgc cgcaaatccg tttgttttga ttgttggagc cgttgttgga gcgattgctg
    45301 tatttggcta ttttatggca accaacgaag aggttagaaa caaagttata tccgtttgga
    45361 atgatgtaaa agattccgta cttggtgtat taaagaatat aaaagattgg ggaattgata
    45421 cttggaattc tgctaaagaa atggcatcaa atgctgttga gagtgtcaag gatgcttggt
    45481 ctggaataaa ggaatggttt tcaaatactt ggcaaggcat taaaaatgga gcaacaggtt
    45541 tatttgataa aacagtagaa acatctatga atgcggttga tagtgtaaaa aacgcatggt
    45601 caaatacaaa gcaatggttt tctgatattt ggcagagcat aaaagattca gcaactgaaa
    45661 aatggaatga aattaaaggt tctatcatgg aagttgctgg tccattgatt acaggtttaa
    45721 agaacgcatt cttgcatgtc actttttatt tagagacctt atggaataat ctagttgaga
    45781 ttggtaaaaa tgtttttgag attttaaaaa atgttatact tacgccagtt ttgtttatta
    45841 cctccatgat ttctggtgga tgggaagaaa caaaaaacaa catgattggt gtatggaata
    45901 atattaaaga aagtgctcta aatatttggg agtctataaa aaatattttt gttagttaca
    45961 ttacaaatat ttattttgct gcgcttaata tttggacagg gttcaaactt actttgataa
    46021 acatttggaa tgaagtagta agtcaagcta aatcaatttg gattaatgta aaatactttt
    46081 ttattaatct ttggattgac attaagtatt ttgctattca aaaatggatt gaattaaaat
    46141 tcgggattat tcaaacttgg attgatttaa aatataatgc tattactact tggaacaata
    46201 ttaaacagtt cttcaaagat acttggcaga acattaaaga tatagcatac aatacatgga
    46261 tttctataaa gaattccatg atcaatactt ggaataacat caaggaatct ttctggaata
    46321 ttgttactgg aattgttaac tccgctgaaa atgcatggac taatctaaaa aatggtgttt
    46381 caaaagcaat taatcgggtg aaagaaatct ttgattcatt aagggaaatc aatttattcg
    46441 aaatcggtaa gaatatcatt gatggactta tcaatggtgt agtagaaaaa tggaatgcat
    46501 tgaaaaagac tattaaagga atagctggaa gtatcaaaga ttctattaag ggtgcattag
    46561 gtattcattc tccatctaga tggatgaggg atatggtagg taaaaatatt gttcaaggta
    46621 ttatcgttgg tattgataaa gaaaaaagta aattggatca gacaatgact gatttagtga
    46681 aaactccgtc ggttcaacca gttattacag ggtctaatag tcaaccagtg gtacaagcta
    46741 aacaaaatac atcttcaaat gcagtgaatg aaattcactt gcatttaaat gtttatggag
    46801 atctacctga ttcgatgatt aaacaaatcg ccaagaagat gaaaacagaa ttgacgagac
    46861 aaatgaaacg agatgctgat gcagtaggag ggacattata tgcaacttaa aagaggacaa
    46921 ttttttatca atcaacatta ttcttctgag tttaacgtat atattcaaaa taggcctgcc
    46981 tctgtttcag ctagtcgtgt aattgaattg agagaacgtg aaggcaatga ctcaattatt
    47041 atcgataaag cctattacaa aaacgttact agaaaaattg aatgttatta caaagcacca
    47101 tcgattgatt tagtgcagga atgggaagat cgaattactg aatggttaga tatgaactct
    47161 tacagtgatt ttattcttta ttacgatcaa caatatatct atcaagctat agtaaccgaa
    47221 gcgccagaat ttaaaggaac aagaaaaaca gggaacatag ttccatttga atttacagtt
    47281 agtcttcgac cattcaaaga aaattatagt ggtcgttttg ctattcaaca gataaaagct
    47341 ttcgagttat ttaatccaga gaagtatgct tcaaaaccgc ttattaaatt gagtggttct
    47401 ggagatgctt ctttttatat taataatgat aaatatgatt tgaaactatt agatagagaa
    47461 ttatatatag attctaaact agaagagtct tatcgaaagc tagatgacaa tttagaacat
    47521 caagatcatg tcactttatt tttagatttt ccatttctat accctggaaa aaatgaaatc
    47581 aaatggacga ataacataca ttcgtttgag ataataccaa ggtggtggag aaaagtatga
    47641 taccaagaat atatagtcct accgagacag atttttctac gaatggttta gggattttga
    47701 aggacaccac aaaatgtgag atatatgaag tagcaaatgg aaaatatgaa ttagagttgg
    47761 agtatccatt aggtactcga tttgatgaat attttgaaaa tgactatcaa ataaaagcaa
    47821 agtcaaatga tcaagaagag tatcatatct tttttattga tgataaagat attgatacct
    47881 ttttagatac cgtaactatt tatgcccaga gtcgtacaaa tcggcttgga agacgagcgg
    47941 tcacttttgc tggagtcgac tctaaaactg gtcgagaagc aatggcaatt attgaaaaca
    48001 atatggataa aaaatcagat atacgcttat attctgatat tacaactgta tcaagtacaa
    48061 cttttgaagc aagaaatgtt ttaaattgta ttgctggtga acaaggatct ttacttcagt
    48121 attggggcgg agaaattaaa cgtgagcctt ttaagctatc tttattaaag cgaagaggtc
    48181 gtgataatat tggcacaatc cgatatggaa aagatttatc tgggttaaaa gttaagttag
    48241 attggacagg cgtgaaaaca agaattattc cgtatgctga tcctcaaagt gatgcaggta
    48301 caactagccg aatttatggc tcgccagtag atagcgaata tattaataat tatcctgatg
    48361 tatatacaga acacgttcaa ttcacagaag aacagggagt taaagacgtt aatagcttaa
    48421 ataaaatagc taagaattat ttcaaaacaa ttaatccagg ctgtgataaa ccgaagattt
    48481 ctattaccgt tgagttcgat aaattaacgg acaccgaaga aggaaaagaa ttcgctaaga
    48541 taagaaatta tgggttattt gatacgttta aaatatatca tcgaaaatat aaactatatt
    48601 ttgaatcgaa agttagcggt gttcaatatg attcattatc tgaaaaggtt ttgaaattgg
    48661 aagctgggga tgctcaagtt gctttttatc aacaacaagc tgttactatt caagataaat
    48721 taaaagatta tgctacgaat aattatatga gtagttttaa tgattatgtg tcctctatga
    48781 ttgcaggtca aggaaatgca ggcggttatg tagttttatg gccaaaagaa aaaccttcaa
    48841 atatttttat aatggatagc cctgatttaa acaaggcaaa agaagtatta agaatgaaca
    48901 aaaatggaat tgccttttct aaaaatggtt ggaatggtcc ttttaattcc gcttggacat
    48961 tggatagtat attcaatgct aattttattc aaacaggatt aataaaggca gatatctttc
    49021 aaaactcttt taataaaact ggagatgtat tgaaattagt taatggacta cttcaaattt
    49081 ggaataacaa aaagaaaata atggagttaa ccaaaaaagg aatggagttt tggaattcta
    49141 atagttcaat tggaacgatt ggaacaactg attctgctgg taatcctttt cctggagctt
    49201 ctactcccac acctattgaa gataattctt tagttattcg tacaaatgga gacggcaaat
    49261 atattttgat ttctcctaaa gttggtaaag gattagtttt attaggaaat ggtaaagcaa
    49321 tttattttgg agacttagat gtacaaggca aactcacagt taacggaaaa gaaatcacag
    49381 ggaacaacag tggaggaagt gatcctggaa ctatccctcc tcaattgacg acggaagctg
    49441 aaaaaagagc atggaaaatt tggacaatgc tgaaagctcg tggctattct gaatatgcag
    49501 ctgcaggtat tctaggaaat attcaggggg aggttggagc aagtatgaac cctgatacag
    49561 aacaacttgg tggtccagct tatgggattg ttcaatggga tggttctgct tatccgttag
    49621 tcggatcacc aacttggaac ggacgagagt atgttcagcg tttgatgaac accgcaggga
    49681 ttcaagaaga ttatcgaagt attgaagccc aagtaaaatt attagattgg tgtatgttca
    49741 acggtcaatg gctcggaaaa gtaaatccaa ccacagtatc aggatttaaa tcgatcaatg
    49801 atgccaaaag tgcagcgtat gcttttgaaa tgaacttcga acgcccagct tctgcacatc
    49861 cagaacgcca aaattatgcc caatcttggt ataacaaatt acatggatta actagtccag
    49921 aacctggagg gaatttcatt tgtccaattc aaaaaccagt gacagttact tcagaatgtg
    49981 gatggagaac tagtccaata aatggcggcc aagaatttca taatggaatt gatcttgtaa
    50041 atggaaatcc taatacacct gtttttgcag cattagatgg ggaagttgtt caggctggtg
    50101 ctaattatta tgactggtat ggtaattacg tggttattaa acataataat gggaagtgga
    50161 caggttatgc tcatttgtct cgtattgatg tttctgttgg acaaaaagtc cagaaaggtg
    50221 ctcaaatagg cttgatggga acaactggtc catctacagg agaacatcta cattttcaaa
    50281 ttatgaaaaa ttattggcca cagccagttg ttgattttga gaatccaaga aattatatcc
    50341 aattttaagg tggtgattct atgagtaaat ggaatgtcgt tttaagtaca acagaaccat
    50401 ataattatgt ggggatgatt caagttcgac aaggcaataa gaatacagag gttatggaag
    50461 cgactatagt tgaaaatggt cttccctacg atttatcaga atgtaaggta tattttgaat
    50521 cagttgtagg tgggaaatat ccagtccaat tagaaacaaa aattgtggat gctaaaaaag
    50581 ggaaaattaa
//
LOCUS       DARPZF010000015        46148 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.015, whole genome shotgun sequence.
ACCESSION   DARPZF010000015 DARPZF010000000
VERSION     DARPZF010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.015"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            46..2211
                     /gene="acm"
                     /locus_tag="SLE65_001186"
     CDS             46..2211
                     /gene="acm"
                     /locus_tag="SLE65_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HEI8448492.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2483..2968)
                     /locus_tag="SLE65_001187"
     CDS             complement(2483..2968)
                     /locus_tag="SLE65_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HEI8448493.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    3058..3403
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3448..4089
                     /locus_tag="SLE65_001188"
     CDS             3448..4089
                     /locus_tag="SLE65_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEI8448494.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            4108..4743
                     /locus_tag="SLE65_001189"
     CDS             4108..4743
                     /locus_tag="SLE65_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEI8448495.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4761..5576
                     /locus_tag="SLE65_001190"
     CDS             4761..5576
                     /locus_tag="SLE65_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEI8448496.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            5895..7331
                     /locus_tag="SLE65_001191"
     CDS             5895..7331
                     /locus_tag="SLE65_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEI8448497.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7520..9967
                     /locus_tag="SLE65_001192"
     CDS             7520..9967
                     /locus_tag="SLE65_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEI8448498.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10197..11264
                     /gene="rlmN"
                     /locus_tag="SLE65_001193"
     CDS             10197..11264
                     /gene="rlmN"
                     /locus_tag="SLE65_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEI8448499.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11457..12560)
                     /locus_tag="SLE65_001194"
     CDS             complement(11457..12560)
                     /locus_tag="SLE65_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEI8448500.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13113..13661
                     /gene="aac(6')"
                     /locus_tag="SLE65_001195"
     CDS             13113..13661
                     /gene="aac(6')"
                     /locus_tag="SLE65_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HEI8448501.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            14206..15867
                     /locus_tag="SLE65_001196"
     CDS             14206..15867
                     /locus_tag="SLE65_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEI8448502.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(15937..16284)
                     /locus_tag="SLE65_001197"
     CDS             complement(15937..16284)
                     /locus_tag="SLE65_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HEI8448503.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            16368..17309
                     /locus_tag="SLE65_001198"
     CDS             16368..17309
                     /locus_tag="SLE65_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8448504.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKTQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            17310..18353
                     /locus_tag="SLE65_001199"
     CDS             17310..18353
                     /locus_tag="SLE65_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8448505.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            18359..19429
                     /locus_tag="SLE65_001200"
     CDS             18359..19429
                     /locus_tag="SLE65_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8448506.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            19419..20372
                     /locus_tag="SLE65_001201"
     CDS             19419..20372
                     /locus_tag="SLE65_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8448507.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            20384..21394
                     /locus_tag="SLE65_001202"
     CDS             20384..21394
                     /locus_tag="SLE65_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8448508.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(21679..22500)
                     /locus_tag="SLE65_001203"
     CDS             complement(21679..22500)
                     /locus_tag="SLE65_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEI8448509.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(22597..22875)
                     /locus_tag="SLE65_001204"
     CDS             complement(22597..22875)
                     /locus_tag="SLE65_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448510.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            23143..25152
                     /gene="metG"
                     /locus_tag="SLE65_001205"
     CDS             23143..25152
                     /gene="metG"
                     /locus_tag="SLE65_001205"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEI8448511.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(25631..26218)
                     /locus_tag="SLE65_001206"
     CDS             complement(25631..26218)
                     /locus_tag="SLE65_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448512.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            26393..27715
                     /locus_tag="SLE65_001207"
     CDS             26393..27715
                     /locus_tag="SLE65_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8448513.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            27870..28646
                     /locus_tag="SLE65_001208"
     CDS             27870..28646
                     /locus_tag="SLE65_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEI8448514.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            28639..29208
                     /gene="rnmV"
                     /locus_tag="SLE65_001209"
     CDS             28639..29208
                     /gene="rnmV"
                     /locus_tag="SLE65_001209"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEI8448515.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            29201..30085
                     /gene="rsmA"
                     /locus_tag="SLE65_001210"
     CDS             29201..30085
                     /gene="rsmA"
                     /locus_tag="SLE65_001210"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEI8448516.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            30536..31165
                     /locus_tag="SLE65_001211"
     CDS             30536..31165
                     /locus_tag="SLE65_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448517.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(31289..32398)
                     /gene="ugpC"
                     /locus_tag="SLE65_001212"
     CDS             complement(31289..32398)
                     /gene="ugpC"
                     /locus_tag="SLE65_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEI8448518.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            32607..33029
                     /gene="mgsA"
                     /locus_tag="SLE65_001213"
     CDS             32607..33029
                     /gene="mgsA"
                     /locus_tag="SLE65_001213"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HEI8448519.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            33352..33888
                     /locus_tag="SLE65_001214"
     CDS             33352..33888
                     /locus_tag="SLE65_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HEI8448520.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(33928..35691)
                     /locus_tag="SLE65_001215"
     CDS             complement(33928..35691)
                     /locus_tag="SLE65_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8448521.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(35694..37409)
                     /locus_tag="SLE65_001216"
     CDS             complement(35694..37409)
                     /locus_tag="SLE65_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8448522.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(38188..38412)
                     /locus_tag="SLE65_001217"
     CDS             complement(38188..38412)
                     /locus_tag="SLE65_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448523.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            38603..41380
                     /locus_tag="SLE65_001218"
     CDS             38603..41380
                     /locus_tag="SLE65_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEI8448524.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            41461..41880
                     /locus_tag="SLE65_001219"
     CDS             41461..41880
                     /locus_tag="SLE65_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEI8448525.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            41892..42362
                     /locus_tag="SLE65_001220"
     CDS             41892..42362
                     /locus_tag="SLE65_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8448526.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            42379..43158
                     /locus_tag="SLE65_001221"
     CDS             42379..43158
                     /locus_tag="SLE65_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8448527.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            43145..43966
                     /locus_tag="SLE65_001222"
     CDS             43145..43966
                     /locus_tag="SLE65_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEI8448528.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            43983..45032
                     /locus_tag="SLE65_001223"
     CDS             43983..45032
                     /locus_tag="SLE65_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEI8448529.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            45045..46049
                     /locus_tag="SLE65_001224"
     CDS             45045..46049
                     /locus_tag="SLE65_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEI8448530.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
BASE COUNT        15257 a         8049 c         9519 g        13323 t
ORIGIN      
        1 atatagtagg ttttattttt agttaaaata ggggagatag aaaaaatgaa aaagtgtaga
       61 aatattattt tatcaatgtt atttattatt actaatataa catcactgat tcctgttcat
      121 gtctatgcgg atgcaggcag agatatcagc agtaatgtca cttcgttgac cgtggaccca
      181 acgaatatta cagatggagg aaacataaaa gtaaaattct cgtttgacga aaaaaaacaa
      241 aatatccaac caggtgatta tctttggatc aattggccaa gtgaaggaaa tattcgcggt
      301 gaaggattcc aaaaagaaat cccattaatg attgaaaata aaaatgttgg aactttaacg
      361 gtcagaaaag attctgcgca ggttgtgttt aatgaaaata ttaaaaacct agactcagta
      421 gaaggttggg ggcaatttga gatacaggcc agaaacgtaa ccgataccgg tgaagaaaat
      481 acgggaccat tcaccgtgac gagcggtgat aaaacagcta ctgtaaatgt gacaaagcca
      541 gcttctggtt cttcttctag cgttttttat tataaaacag gagacatgct acctgaagat
      601 actaagcaca ttcgatggtt tttgaatatt aacaataacg gcacttatgt tgaacaacca
      661 gttaaaatca gtgatgaaat ccaaagtgga caaagattag atccaagtac gtttgaaatt
      721 aatcaaatac acttaggtga acagaaggtt tatagaggag aagagggaat ccaacaattt
      781 ttacaagatt tccccagcgc tacatttaat ttttcagtaa ctgataatta cattgaaata
      841 actataccaa aaaactttgt caatcttagg aaaataatgg tgagttataa gacgatcata
      901 gaaaacccag aacaaataaa ttttgagaat cattcggaag cttggtttaa agaatttaat
      961 aaacctgctg ttgatggaga aagtttcaat catacagtta aaaatatttc agcttctggt
     1021 ggagtcaacg gtacagttag aggcgaattg aagattttca aatatatcaa tgacacagag
     1081 attggtatcc caaatgtgac tttcgaatta agacgagcag atgaacagcc tattcaagga
     1141 cagtctagta tcctgttgac ttcgaatgaa cagggagaag ctagtatcaa aggcctgcaa
     1201 gtaggagact atgttgtaaa agaaaaagaa gcacccaatt ggattgattt tgatccacta
     1261 agttcaaatg aactcaaatt ctccataaac gaaaatgata cagagggagt cagtttacct
     1321 atttataaca agaaaaaggt tacgaacatc acagcaacta aaatttggaa cggtggaacc
     1381 actccaagac cgagtattta ttttaaatta ttcagagcaa gtacaaacaa ttgggaacca
     1441 gttcctgatg cagaaacaaa acgattagac aatggaataa cttcagtgac ttgggaagat
     1501 atccaacagt atgatgatag tggaaacgaa tatacgttta aagtgcaaga agtagatcaa
     1561 aacggaaatg attatgtccc ttcaggttat caaaaaattg aaaacgggct agtcgttaca
     1621 aatgagaata aagaagtcat ttcagtctca ggacaaaaaa catgggaaga caatgagaac
     1681 caagacggca aacgaccgac gacgatcaca gtaaatctat tagccgacgg tcaaccgatc
     1741 caacacaaag aagtaagtga aaaagatgat tggcgctatc gtttcacaaa tctgccaaaa
     1801 tacagagacg ggcaagaaat catctatact gtaacggaag acaacgtgcc cgaatacagt
     1861 acgacgattg acgggtataa catcaaaaac agttatacac cggaaaaaac aaatatatct
     1921 ataccaggta gccatataac accgtggaaa aattttccag agaagacaga gagagagaaa
     1981 attagaaatc tattctctca aaaattgcaa atatttgctc atacaggaga atccagcgaa
     2041 caaagaagca attatattag taagagagct gtacctaaac agataacaaa taaatcaaaa
     2101 agcattcttc ctaaaacaag tagtaaaaaa tctagttttg ctgtaatcat tggtttattg
     2161 atagtaacta tctgtgctgg gatattctta caaaaatata aaaaagttta gttagaatat
     2221 aatatttttt gttaaatatg actgaaatca aaagaataaa attccgattt ataatcgaaa
     2281 aaagaagcat ttttatatat gcttcttttt tcgtagaatc aataaatatg gatttggcta
     2341 actatggaag aatactcgta ttagttttca gcgttcatac tagttgttac attgtttgat
     2401 tggccaaaag aatttctgat atattttgtg ctaaataaag aaaaagacgc ttgaattggg
     2461 aaataagaaa actactctat cattacaaat tttcataaac tggcagatgt tctaagtaaa
     2521 caagtatctt ttcaaagtcg gaaaaatcca taatcaacgt agtggtattg atatttggat
     2581 gaaagcctac ggtatcttga cgatcaatag cagcatcgat cacgacttgg atttttttct
     2641 ctttgtcgtg catcaatgct aatggagtca ctgtacctgc tggaacgcct aggaggtcag
     2701 gaagctgttc ttcagaaaca aaagataagc gcttttcttt taattgttca gctagttgtt
     2761 ttaaatcggc gtgcttttca tcaggcaaga tgacaagata gatttgtttt ccttttcttg
     2821 atttcaataa tagatttttt acttgcggac caggtaggga aaaagggaca tttttgactg
     2881 acgtaatcgc aggatgatcg actttttgaa aagagatacc cagttttttt agtagttcat
     2941 aagcttcttg ttcggttgca cgactcatcg cgcatcaccc tccttttttt attagtgtat
     3001 cataaaaaag agttgacaaa tgaaaaataa tcatgtaaat tacacgtaaa gttaaaacaa
     3061 atgacatcga aaagaagagt agccgttagg tgtttttaga gagtctctgg ttggtggaaa
     3121 gaggcagcag ttaaccgtga aacacatctt ggagtcgatt ttctgaagcg tatagtagga
     3181 aaatccgggg agcccgttac agctgcggtc gttgctagat gaccagataa ggctggcttt
     3241 tccgtgagga gtcggtaaaa aaaggtggaa ccacgtgatt aacgtccttt gatcttcgga
     3301 tcaaaggact ttttgttttc atctgaacgg caacgactgt gtgaggtttt ttctgcaagg
     3361 aaaaaataaa cagaggtgga accacgtata atacgtcctc ttggcatttg ccaagaggat
     3421 ttttttattt taaaggagga aaagaagatg gagtatttga ttgaagttat gccgcaatta
     3481 ttagtaggag cactcacaac attgaaatta tttttattta ccttgattgg ctcattacca
     3541 ttagggattg ttttagcatt aggattgtct ttgcatttta agccgctacg ctacttgctt
     3601 caaacatatg tatgggttat gcggggaaca ccgctgttgt tgcaactgat ttttattttt
     3661 tatgggttgc cgacgattgg gatcgttttt gatcgtttcg aagcagcact cattgccttt
     3721 atcttaaact atgcagctta ttttgcagag atctttcgtg gagggataca atcgattcct
     3781 caaggtcaat atgaagcagc gcaagttttg caattaagtc cctttcaaac ggtgacgaaa
     3841 atcgtcatcc cacaagtgac aaagattgtt ttaccttctg tagggaatga agttatcaac
     3901 ttggtcaaag attcttcctt gatctatata ttaggtttag gtgacgtaat gcgtgctggg
     3961 aaaatcgcga tggaacgcga cgcgacttta ctgcctttgc taggcgtggc aatcatctat
     4021 cttacattga ctggtattct aacaatcgta atgaaacaag ttgaaggaaa attaaattat
     4081 taccgctaac tgataggagg aagaaatatg attgaattga agaaagtgaa caaagcattt
     4141 ggtgaaaaaa aaataatcaa agatttgaat ctaatcattc cagatgggaa aacattagct
     4201 atcgtaggtc cttccggtgg cggtaaaacc acgcttttac gtatcttggc tggcttagaa
     4261 agttctgaca gcggagaatt ttatttagac ggtgtaccgt tcaacccatt cgagcttaaa
     4321 atgaaagaac aagttgtagg agtcgtattc caagacttcc agctatttcc acatctgaat
     4381 atttttgaaa acattacctt agcaccaaaa atggtattga aacagacaaa agaagaatac
     4441 accaaaaaag cagaagaatt agcggcttca ttagggatta gtgatttatt gaatatctat
     4501 ccttatcagc tttctggcgg acaaaaacag cgggtagcga ttgccagagc attggctatg
     4561 aatccacggg tattggctta tgatgaacca acaagtgctt tagatcctga attacgccag
     4621 caagtcgagc gtttgatcct atcattgaaa gaagatgggg taacccaaat tattgtcacc
     4681 catgatttag tatttgcaga aaatgtcggt gatcaattac taaaagtttc cccaattcat
     4741 taagaaagga gaagatagag atgaaaaaaa ccagttttct attcgctttg atcgcaggtc
     4801 ttcttctttt tgcaggctgt tcgaacaaaa aaacttcagc agataattgg gcgactatca
     4861 acgaagagaa aaaaatcgtt ataggtttag acgatacatt tgttcctatg ggatttagag
     4921 ataaagacgg gaagctcaca ggatttgata ttgatttagc caaagcagtc tttgaacaat
     4981 atgggattac ggtagacttt cagcccattg actggtcaat gaaggaattt gaactgaaca
     5041 atggaacgat cgatttgata tggaacggct attccaaaac gccggcaaga gaaaagaaag
     5101 tgcaatttac aaaaccttat atggaaaacg atcaagtgct gatcacacct aaagaatcag
     5161 gaatcacaaa ctttggacaa atgaataata agagattagg tgcgcaaaat gggtcatctg
     5221 gttatgatgt atttacgaaa caaccagaag tattaaaaga gatagtcaaa aaccaagatg
     5281 ctgttttgta tgatagtttt aatgaagcat tgatcgatct gaaaagcaga cgggtcgatg
     5341 gtctgctgat ggataaagta tacgcagact attatttgaa acaaagaaac gaactagaag
     5401 acttcaacat aacaaaaggt tcttatgaga gtgaggattt tgcagttggt gcacgcaagt
     5461 cagatagtac attagtgaaa aaaatcaatg aagccctaga tcaactagag aaaacaggtg
     5521 aattccaaaa aatatccgat aaatggtttg gcgaagatgt tacgccgaga aattaacaaa
     5581 taggggactg tgacaaaaga cgtgtcacag tccctttttc cgaataaaca gtgttctcct
     5641 gccaactcct tgtgactcgg agctgaatgg caggctcaca acctcttggt aaacggtgtt
     5701 caaaagccag tttttcggta ttaagccaaa tttatgcaaa aatgtagaaa gccattttca
     5761 caaaattttt cttactactc gaaactaagc gactttttca caacctcctt tacatatttt
     5821 tattttgttg tggaaggggt ttcgtgttat tctaaaagag gaacgattga aggttatagg
     5881 aaaggaagag atgaatggaa cacaaagaac ttacctcatt tccaaaagat tttctgtggg
     5941 gctctgcttc tgcagcgtat caagtagaag gagcttggca agaagatggg aaaggagaat
     6001 cagtctggga tcgatttgta cggatacctg gaaagacatt taaaggaacg aacggtgatt
     6061 tggcagtaga ccactatcat cgttataaag aagatattgc tttaatgaaa gaacaaggtc
     6121 tgaaagctta ccgcttctct gtagcttgga cacggatttt tcctaatgga cgaggagaag
     6181 tcaatcaagc tgggctcgct ttttatgaga gattgatcga cgaattgatt gaaaacgata
     6241 ttgaacctat gttgacttta tatcattggg atcttccaca agcattgcaa gatgaatata
     6301 atggttggga atcacgtcag atcattgaag atttcactca ttatgcagaa acattatttg
     6361 aggcattccg cgggaaagtc cattactgga ttagtttgaa tgaacaaaat atcttcactt
     6421 cattaggtta tttgttagca gcacatccgc caggtgtgac agacccgaaa cgaatgtatg
     6481 aagttaacca tattgctaat ttagcaaatg catctgtcat caataaattt cacgagttag
     6541 aaatgcctgg aaaaatcgga ccaagctttg cgtatacgcc aaattatcca attgacagta
     6601 atcctgaaaa tgttctggct gctgaaaatg cagaagacct gatggccaat tattggatgg
     6661 atgtctatat gtggggaaaa tatccgattg ctgccatgag gttcttagaa gaaaaaggat
     6721 gggcaccaac gattgaagct ggcgatgcag aattgctaga atctgctaaa ccagattttc
     6781 ttgggatcaa ttactatcaa acggcgacga atgcattcaa tccattaaac ggagttggtg
     6841 ctggaaaaat gaatacgaca ggaaaaaaag gttcatcaga agaaactgga gttcctggaa
     6901 tgtataaaaa agttgagaat ccatttgtcg aacgaacaaa ttgggactgg gagattgacc
     6961 cagaaggatt aaggatcgga ctgcgtcgta tcacaagccg ttaccgcatg ccggtactga
     7021 ttacggaaaa tggcttagga gagtatgaca agttgacaga agataaacaa atccatgacg
     7081 actatcgaat caattactta caaagccacg tcaaagccat caaagaagca atttcggatg
     7141 gagcagaagt cctaggctat tgcacctggt cttatacaga tttgcttagc tggctgaacg
     7201 gttatcaaaa gcgatatgga tttgtatatg ttgatcaaga cgaaacacaa gaaggatctt
     7261 tggaacgata taagaaagac agttattact ggtaccaaaa actgattgaa gaaaatggag
     7321 agaaccttta gttcacatac ttaaaacaag aaggtacggc tggatatggc cgtgcctttt
     7381 cttgataaaa tcatttagaa attaagaaaa actgtaaaat aagctgaaaa atgaaagaaa
     7441 gcgtcagttc tttcaaacaa aactttagtt cccttacttt tttttgtata atgaaacttg
     7501 atgaaatgag ggataataaa tggcacaaaa gaaacggcct actaaaaaaa ggaaaaagac
     7561 gaaaaaaacg aaaaagcaaa aacagcagca ggaacaaatg ctgacgattg gtgttgggtt
     7621 tgccttgatt ttatttgctg tcttcggctt tttaaaatta ggttttttag gaatattgat
     7681 tgcaaacggc tttcggatca ttgcaggaaa tacttaccaa atcctctgtc ttttattagc
     7741 cgtattagga ttttggattg tcattaagaa tacagagttt tcaattggta aaaaccgacg
     7801 ctggtttggc ggcatactct tttatttcgg tatcttatta ttgttacatg cccatttatt
     7861 tggcaaactc catactgggg aaccaaatat catggggacg acatgggatt tgttagccag
     7921 tgatataaaa caaagtcaag tagacaataa cgttggtggt gggatgattg gagcaatcct
     7981 ttatcatttt acttacttct tgattgcaca gcctggaagt tatttagcag cagtgctatt
     8041 actggcagga ggagcattcc tgttcagtaa tctggaaggc tatcagctgt taaatggtat
     8101 ccaatcaatt ggagaacgag tacaggaatt attggaaggt gatcctgcca agcaagctcg
     8161 aaagcaagcg gcaaaggaag agagaatgaa acagcgcgca gaagcgaaag aagcaaggcg
     8221 cttagctgca aaagaagctg cagaaaaaga agctgcagaa tatgagaaga aaaaagcggt
     8281 gagccagcaa agggaaaata ctgctgatga atggcaggaa ccagaaaata cagagccgga
     8341 gcagctaagt tttgttccaa tcgacagttt tcaagaaaat atccatcctg cgaatctaga
     8401 gaaaccagta ccagatacac caaaacagac caatacagca gaaggttttt cagatgagtt
     8461 gccagaggat gacggtacct cattagaatt tgagattgaa gcagaacagg aaaatcaaga
     8521 ctatgaatta ccgacagttg atttgcttga ttctatacca actgtggatc aaagtgatga
     8581 gtataaaaaa attgaaaaaa atatcggcgt attagaacaa actttccaaa gtttcggtgt
     8641 cgatgccaag gtcgtcaaag ccagcttagg accatccgtc acaaaattcg aagtccagcc
     8701 ggctgtaggg gtaaaagtaa gtaaaattgt gaacttaaca gatgatatcg cgcttgcttt
     8761 agcggcgaaa gatgtccgga tggaagcacc gattccaggt aaatcactga ttggtattga
     8821 agtaccaaat ggaaagatca gtatggtttc ctttagagaa atcatcgaag cacaaccaaa
     8881 ccacccagat aaattactag aagtaccttt aggacgtgat gtttctggac gggtacaaac
     8941 ggctgatctt tcgaagatgc ctcacttact cgtggctggt tcgactggta gtgggaagtc
     9001 agtagcaatt aatgggatta tcacaagtat attaatgcgt gctaagcccc atgaagtaaa
     9061 actgatgatg atcgatccga aaatggttga attgaatatg tacaacggca tacctcatct
     9121 gttgacgccg gtcgtgacga accctagaaa agcagcgcaa gccttacaaa aagtagtaca
     9181 agaaatggaa gaacgatatg aaaaattcgc ggcaaccgga gtaagaaata tttctggtta
     9241 caatgaattt gttcaacaga aaaacttgga aaacggaacg aaacatccaa ccttaccatt
     9301 catcgtagtg atcgtagatg aattagctga tttgatgatg gtagccagca atgaagttga
     9361 agatgcgatt attcgtttag cgcaaatggc tcgggcagcg gggattcata tgatcctagc
     9421 tactcaacgt ccaagtgtgg atgttatcac aggaatcatc aaagcaaatg taccttccag
     9481 aatggcattt gcggtatcaa gcggtacaga ttctcggacg atcattgatt ctaatggggc
     9541 agaaaagctc ttagggcgag gagatatgct attcttgcca atgggtgaga ataaaccgat
     9601 ccgtgtgcaa ggagcattca tttctgacca cgaagtagaa cgggtcgttc aatttgttac
     9661 agatcagcaa gaagctcatt atgaagagaa aatgatgccg acagatgaag ttgaaacgac
     9721 aggtgctcca gaacagccac aagatgagct gtttgaagaa gcaaaagcac ttgtcgttga
     9781 aatgcaaacg gcaagtattt cccttctcca aagaagattt cggatcggtt acaaccgagc
     9841 agcacgttta gtagatgaac tggaagctca tggagttgtt ggcccgtcag aaggaagcaa
     9901 gcctcggaaa gtattcattg agcaggaaga aacatcagaa acgttgccgg acgataatga
     9961 catgtaaaac ttgtgtgatg aagggttgaa aaacgaataa ccaataaaaa gacaaggcat
    10021 gatgatacca aaagaaaaaa tggttttttt ccatcttttc taatacggta tgatgtcttg
    10081 tctttttagt ttttgtgaga ttaaagttct attcgattta tttgtgaagt attgcattaa
    10141 ggaaatgaat catgtatagt atgtagcgaa actttgagaa aaagagggaa aatactttgg
    10201 aaaaacagtc catttatggc ttgacgaatg aagaattaat caattggttt atagaaaacg
    10261 gcgagaaaaa attccgagct gcccaagttt gggaatggtt gtatcaaaaa cgtgtaagta
    10321 atttcacaga aatgacgaat ctatcgaaac aattgatcga aaaattatcg gagcatttta
    10381 tcatcaatcc tctaaaacag atggtcgtcc aagaagcttc ggatggtaca gtaaaatatt
    10441 tgtttgaact ccctgataaa aacatgattg agactgtact gatgagacaa gaatatggct
    10501 tgtcagtttg tgtgacgaca caagtaggat gtaatatcgg ctgtacgttt tgtgcaagcg
    10561 ggctgctcaa aaagaaccgt gatctgactg ctggagaaat tgttgcacag atcatgatgg
    10621 tccaacatta ttttgatgag cgcaatcttg gcgaacgcgt ttcacatgtc gttgtaatgg
    10681 ggatcggtga gccatttgat aattacgaca atgtaatgga ctttttgcat atcatcaatg
    10741 atgccaaagg attggcaatt ggtgctcggc acattacagt ttccactagt ggattagcac
    10801 acaaaatcaa ggaattcgct aataacggct tgcaagtcaa tctggctatt tccttgcacg
    10861 cgccgaataa tgaggtgcga acatcgatca tgcggatcaa ccgaagtttc ccaattgaga
    10921 aattgatgga agctgtggat gagtatttag agaaaacaaa ccgtcgaatc acgtttgaat
    10981 atatcatgtt gaatcaagta aatgatagac cagagcatgc gcaacaatta gcagatctat
    11041 taaaagataa gaaaaaatta gcatatgtca acttgattcc atataatcca gtcagtgaac
    11101 atgatcaata ttctcgcagt ccaaaagctg atgtattgag attttatgat gtattgaaga
    11161 aaaacggcgt aaactgtgtg atacgtaaag aacatggtac agatattgat gcagcttgcg
    11221 gacaattgcg aagcaagcaa atgaaaaaaa cagttgccaa ataatcgtat cctactcgtt
    11281 ttttcaatta ccataaaagg agcagttttc ttaattaagg aactgttcaa cttaaataag
    11341 agaaaagatt ctatagcgaa agctataaag ctttttttga caagaaaaac cctcatcaag
    11401 caaagaaatg tcctcaattt gatgacagcc tgcttgatgg gggttttagc aattatttaa
    11461 ctgattttct tatatccttg ctggctttct tgtgtagcat gataagtttc tacgtcaaga
    11521 atggcctgtt taaatttttc tcgggtgatt tcataaggca catgtttaat atcatttgtt
    11581 gccatggctt tatctaagat tgcttctaaa tcggtcgtga cattgagatt catgtcggtt
    11641 aacgatactg gaagttggtt ctttttcata aacacataga ttttatcaaa caaatcgaac
    11701 tgctgatcca tcatcaataa ggtcagtaca ccataactga cagatgctcc gtgaaggtat
    11761 ccctccattt tttctagaac agtcgtaccg taatagaatg agtgtgccat agcagaatta
    11821 tagttattgt taactaaaac agaaaccaat ccggtagtaa caatgatatc cgaaacgact
    11881 tgttcaattg catatgaggg acgatcgtcg gcactatctt tcaatgcttg cgtaccataa
    11941 gtcaagagac gatcaatgca catttttccg atttggattc ctaatctatc cgtgtagcct
    12001 agatcatcgc cacgagcaga aaaagtagat tcgacttctt tggataaagc atcgccaata
    12061 cctgcccata agtatttatc aggtgcttcg gcaataattg ctgtatcaat gaaggtgtgt
    12121 acaggtggtt ttgaaggaaa gaagagtccg tccattacgc cttcttcgtt atagatgaca
    12181 cataccgcag tgacgggcga acagttcgaa ccaatagtgg gaaaggtgaa gactggttta
    12241 gctagttttt caccaatgac ttttacagta tcgcaagcac ggccaccacc gactgcaaac
    12301 aggacgtctg ctttttggac actttcatgc tggatcaact gttcaatatt tccataagtt
    12361 gaattacccc cgtaccagag actggcgaca acctctattt cctgtgtcaa agctactttt
    12421 attttgtttt ctgcctttga aagtgcagtc ttccctccaa tcagcactac ttttgtccca
    12481 tattctttga cgattccatt tgctttttca tacgcatctg ttccaatggt ataatttggt
    12541 aagaaaacac tttgactcat attcatttcc ttctttcttc gttgaaacgg gttaaaattt
    12601 taaagagtga tcgatctgac tgcggctgta gatggagtag aggtgaacct aagacaggat
    12661 aagtgatgaa taaggtggca tgaacacctt gaaatcatca ataagtatcc taaaaacgaa
    12721 caagtacaaa aacattgaaa acgacaataa tgaatttttg ttcctcttag tatttctacc
    12781 gattcccttt gcttttttgt aattatctaa aaattctaaa aattaagatt attatatgaa
    12841 aacaggtttt atttgtcaat tcataattgg ttttttttaa agcaaaagat aatctatatc
    12901 atgatgaaca aacagagttt tttcctccaa ttgatggctt tcctgatctt tcctattttg
    12961 aataaagtgt ttctgtataa tttttttatt ttataagtaa gataaataat gaaagaatag
    13021 agatactgat tggtagctaa agatttttga gcgagaacat ttcgtttttt caaaaggact
    13081 gttagaataa gcaagaacaa gggggaagac gtatgataat cagtgaattt gaccgtaata
    13141 atccagtatt gaaagatcag ctttctgatt tactgagact gacttggccg gaagaatatg
    13201 gagacagctc ggcagaagaa gtagaagaaa tgatgaatcc agaacgaatc gcggtagcag
    13261 cggtagacca agatgagtta gtaggattta ttggtgcaat ccctcaatac ggtatcacag
    13321 gttgggaatt gcatccatta gttgtagaaa gctcccgacg aaagaaccaa ataggtactc
    13381 gattagtcaa ttacttagaa aaagaagtag cttccagagg aggaatcacg atttatttag
    13441 gtacggatga tttagaccat ggaacaacgt taagtcaaac ggacctgtat gagcatacat
    13501 ttgataaagt ggcttccatc cagaaccttc gtgaacatcc gtatgaattc tatgaaaaat
    13561 taggttataa aatcgtaggt gtcttaccaa atgcaaatgg ctgggacaaa ccggatattt
    13621 ggatggcaaa aacgattatt cctcgaccaa attctcaata ataaaaagag gttgtgacag
    13681 aagtaatcag cttcaagaaa taagaaggaa tttacgaaaa ttacttcttg aatttttgtg
    13741 aaattccaac ttatttccga agaagctact tttggaacac cgtgtaccag aggttgtgaa
    13801 aaagtcgctt agtttcgagt agtaagaaaa attttgtgaa aatggctttc tacatttttg
    13861 cataaatttg gcttaatacc gagaaactgg cttttgaaca ccgtttattc agataaggga
    13921 ctgtgacaag acttttgtca cagtttcttt ttgtttattc ttttttatct ttgtatggca
    13981 ataatagaca atataacgaa aattatttaa tggcttttgg aagaccatgg aaaaccttgt
    14041 acaaagctat tttttctgaa aaattccttg aaacctcacg aaaaaatcat tattttatga
    14101 aaaagacaaa aaaagtgttg attttttaat aattattcat taaactctta aacaacttca
    14161 gaaaatatta attattctga aaattccaat aaaggggtac gtaaaatgaa aaagaaattt
    14221 acatttggtt tggttgcggt atgcggcctt gtacttgctg gatgttatgg cggcagttca
    14281 gccacaagca gtagttcagc aaaaagcggt tcagcagatg gaggaggcgt atttaactta
    14341 gtcgtgcctc aagaaatgcc tacagctgac ttatcagttg caacagatac aatcagtttt
    14401 acagcattga ataacgttta tgaaggaatt taccgtcttg atgaagacag caaaccacag
    14461 ccggcaggag ctagcgagtt ggcagaagtc agtgaagacg gattaactta caaaatcaaa
    14521 ttacgagaag acgcaaaatg gtcaaatggt gatcctgtta cagcagcgga ttacgtttat
    14581 ggctggcaac gaacagtaga cccagctaca gcttctgaat atgcttacct gtatgcgcca
    14641 gttgaaaatg cagaagacat tacagctgga aagaaagata aatcagaact agggatcaaa
    14701 gcagttggtg actatgaatt agaaatcaaa ttgacgaaac aaacaccata tttccaatat
    14761 ctgcttgctt tcccatcatt tttcccacaa aaacaatccg tagtggaaga aaatggggat
    14821 gcctatgcat ctgcaagtga taaagctgtt tataatggac cattcacatt agaagatttt
    14881 gatggaccag gaacagatac agaatggact tataagaaaa atgatcatta ctgggacaaa
    14941 gatacagtaa aactttctga aatcaaagtc agtgtagtaa aagaatcttc tactgcattg
    15001 aacttattca aagatggcca agcagatgac gtgatcttgt ctggtgagtt agcacagcaa
    15061 aacgcaaacg atccagctta tacttctgtt aaagaagcgc ggacaagcta tatcgaattc
    15121 aatcaacgtg aaaagaattc accattcaac aatgtgaacc taagaaaagc tatttcttat
    15181 tctatcgatc gtgaagcttt agtaaaacaa gtactaggtg acggatcagt tgtctctaca
    15241 ggattgatcc catcagatat ggtaaaaagt ccaacaacga acgaagactt tgcaaaagaa
    15301 gctggaaaat tagtttctta tgacaaagat aaagcaaaag aatattggga aaaagcgaaa
    15361 aaagaattgg gcgttgattc tttagaattt gatttgatgg cttctgatga tgattcatcg
    15421 aaaaaagtaa tcgaatatgt tcaaaactca atccaagaaa acttggatgg cgtaacagtc
    15481 aaaccaacac ctgttccatt ctctgtacgt cttgaccgct caacttcggg tgattttgac
    15541 gcagtactag gcggatgggc tgctgactat gcagacccaa gcagctttac tgatttgttt
    15601 gtcacaggta attcatacaa ccgtggtcgc tggagcaatg cagaatatga cgaagcagtt
    15661 aaagcagctt catcaacaga cgctggcgat gaacaagccc gttgggatga tttccaaaaa
    15721 gcaatcaaga tcatctctga tgatatgggt gtcgttccgg tgtaccaaaa agcagaaggt
    15781 cacctagtga atgaaaaaat caaaggtatc gttcaccatg cggcaggcgc ttcatgggat
    15841 tacaaatgga catacgttga agaataatcg ttaataccgt gagcatgaga aaaaacgagg
    15901 ctgcggcaaa tgtcgcaacc tcgttctcat attcacttat cctaacaaag aaaaaagcat
    15961 gaaaatagca gaaagagcaa ttagtattcc ggcaatgatc agccaaaagc tgtacatacc
    16021 gtagctggca gacgagagcg aggaaaattc tggttttttc tttcggttcc ttgttcgtgc
    16081 aagatggacc gatcgctgaa aatgatcgaa gaaacccgaa gaaaagaccc ataaaaaacc
    16141 gccgataatc agaaacggca atgaccataa gaatagatca ttagataatt gaatgagtgt
    16201 aaaggaatgg ttgatgagat tttttattaa aataaccaga atcagtagaa aagctactgc
    16261 gtaggggata gatttttttt tcatttgatt gctcctttat ttttggttca ttatctaata
    16321 atgtagcgaa acatctgtca gaagtcaaaa gctaggggga aacattagtg aatagttata
    16381 tcaaatatgt attaaaacgt gtctttttca tgatcatcac gctttggtta attgcaacaa
    16441 tcaccttttt cttgatgcaa ttgctgccgg gcacgccata tacgaatcag gaacgtttga
    16501 gtcctgaaac aatcgagatg ctaaataaac aagtcggttt ggataaacca gttatcgtac
    16561 aatatgggat ttatctttct aatttgcttc aaggagattt tggaatttcc ttccaattta
    16621 aaacccagcc agtcgcacat ttgttagctg gaagaatcgg accatccttg cagttagggt
    16681 tacaggcaat tatctttgga acagtcctag ggacgatttt aggaacgatc tctgccatga
    16741 agcaaaatac atgggcagat acatcttcta cactcgtagc gatattaggt cgttccattc
    16801 caaactttgt atttgctgtt ttattacaat atatctttgc aatcaaatta caagttttgc
    16861 caatcgcaaa atgggatggc tttgtgtaca caatcttacc aacaattgcg ttggccatgt
    16921 cgccgcttgc tgactctgct cggtttatcc gtacggaaat ggtggaagta ctgcatagtg
    16981 attatgtgga attagcaaaa gcaaaaggat tgagccgttg ggaaatcgcc tttaaacatg
    17041 gtcttcgaaa tagtttgatt ccattgatga ctttattagg accgttagct gtagcattga
    17101 tgaccggatc actggtggta gaaaatatct ttgctattcc tggtatcggg gaacaattcg
    17161 ttaagtcaat cacaacaaat gattatccta cgatcatggc tgtaacgatc ctttactcat
    17221 ttatgctgat ttttgttatt ttgatcgtgg atctattgta cggtctagtt gatccaagaa
    17281 ttcgtgtttc agaagggagc cgaggataaa tggaaatgat accaaagcgt tatgaaacag
    17341 ttgcagatat ccctgcggat gaatttcttc cattacaaaa aaataccgaa gaagaacgtg
    17401 aacagattac tgcaccttct ttgaatttta tccaagattc atggcgccgt ttaaagaaaa
    17461 acaaagctgc cgttatttca atggttttac tattggtcat cattttgatc tctgtgatca
    17521 caatctttgt ttctcctcat gatccaactg cccaaaacgt ggcttatatc aatttgcctc
    17581 ctcgtattcc gggaatcaat atcgatggat tgaatggaaa agcaatggtt ggtggtgaac
    17641 ttgttgataa atatgctcaa gcaaacgtcc cttcaaacgt aaatttcttt ttaggaacag
    17701 acggtttggg acgtgatgta ttaagccgct tatttatggg aatgagaatc tcgttgctga
    17761 tcgcatttat tgctgcatta ctagatgtaa cgattggtgt agcttacggg ttggtttctg
    17821 gtttgttagg cggacgtgtc gataacgtga tgcaacgttt tttggaaatc ttatcaggaa
    17881 ttccaaacct cgttgtcatg attttgatgt tggtcgtttt tgaaccagga attttttcaa
    17941 tcgtggctgc tatggccatc acaaactgga taccaatggc acgtatcgtt cgtgcacaaa
    18001 caatgaaatt aaaagatcaa gaatatgttt tagctggatt gacattaggt gaatcaagaa
    18061 tgaaaattgc attcaaacat attttgccga atatctctag tgtcattatt attcaaatga
    18121 tgtttagtat tccatctgct attttcttcg aagccttttt aagctttatc ggtttaggtc
    18181 ttacgcctcc gtcagcttca ttaggaacga tgttgagcga agggtacaag acattcctgt
    18241 atctgcctta tctattatgg attccggcag taactttatc ggttatcatg attggcttta
    18301 acttacttgc tgatggattg cgtgatgcct ttgatcctaa aatgaaagag tgaagacgat
    18361 gacgaaaatt ttagaagtga aagacttaga aatctctttt gatacgtatg ctggaaaggt
    18421 acgagcgatt cgcggtgtca attttcattt gaataaagga gaaacattgg cgatcgttgg
    18481 ggaatctgga agtggaaaat cagtgacgac cagaagcatc atgcgcttgc tgtcaagcaa
    18541 cgccaatata gatgctggtc aaatcctctt taaaggtaac gatatcgttg gaaaatcaga
    18601 aagagagatg caaaaaatcc gtggtaaaga aatagcgatg attttccaag atccaatgac
    18661 ctctttagat ccgacgatgc ccattgggaa gcaagtcgct gagtccctta gaaagcataa
    18721 taaagtttca aaaaaagagg gacaaaaagc tgcattagaa ttgcttaaat tagttggaat
    18781 acccgaagct gagaaacgta tcaacagtta tccgcatcag ttctcaggag gtcagcgtca
    18841 acggatcgtg atcgcgattg cactggtatg ttatccggaa atcctgattg ctgatgaacc
    18901 tacaacagcg cttgatgtga ctattcaagc acagattttg gagctgctga aagaaattca
    18961 gacaaaaatc gatacatcaa ttatctttat cactcatgac cttggtgtag tagcgaatgt
    19021 cgctgatcgt gtcgctgtca tgtatggagg aagaatcgtt gaagttggaa catcggaaga
    19081 aattttctac aacccgcaac atccctatac ttggggactg cttggttcaa tgccgacatt
    19141 agatagtgcg aacgatcgat tgtatgctat tcctggttct ccaccggatt tattgaaccc
    19201 gccaaaagga gacgcattct atccaagaaa tgaattcgcg atgaaaatcg atgcagaaca
    19261 agaaccacca ttttttgaac tatcaaaaac acacaaggca gcaacttggc tacttgctcc
    19321 gcaggcaccc aaagtgacac cgccagaaga aatccaacgt cgctgggcta tctttaaaga
    19381 gaaacaaaaa catacttacg gtcaaggagg aattgctgat gccaaataaa ctacttgaag
    19441 ttaaaggatt gaaacagtat ttcaatgtag gaaaaaagaa tgaagtacat gctgtaaatg
    19501 acatcagctt tcacatttat gaaggagaaa cattcggttt agttggagaa tctggaagcg
    19561 gaaaatccac tactggccgt acgatcattc gcttgaatga acctactgat ggtgagatat
    19621 tattcgacgg tcaagatata acgaagatca aagataaaaa aggtttgacg aaattccggc
    19681 atgatgttca gatgatcttt caagatccat acgcttcgtt gaatcctcgt atgaaagtca
    19741 gagatatcat tgccgaagga attgatgtta atggactagc taaatcatct gaagagcgtg
    19801 caaaaaaagt cgatgatcta ttgagaactg ttggattgaa tccaagccac ggtactcgtt
    19861 atcctcatga attttcaggt gggcaacgcc agcgtattgg tattgcacga gcattggcag
    19921 taaaaccgcg ttttatcatt tgtgatgaac caatttctgc actagatgtg tcgatccaag
    19981 cccaagtggt caatttgttg caagatctcc aaaaagaaca tcaattgacc tatctattta
    20041 ttgcacatga tttgtcgatg gttaaacata ttagtgaccg aatcggtgta atgcataacg
    20101 gcttgttatt agagatggga acaagtgatg aaatctataa tcacggtgtt catccttata
    20161 cagaaagttt gttatctgct attcctctac cagatccaga ccatgagaga aaacgcagaa
    20221 gaatcaaata tcaacctgaa ccagatgacg gacaagtacg tcaacttcgt gaaatcgcac
    20281 cagaacattt tgtctatgca actgagcagg aagtcccata ttacgcaaaa aaactaaaac
    20341 gacaaaagga atctcttctg gttgctaact aggagggaca tagatgctaa aagcttttaa
    20401 attccgtatg tatccgacag aagaacaaaa acagcaattg attcgtactt ttggatgtgc
    20461 tcgatttacc tataaccatt tgctgaaaaa gcggcagaaa agttggcaac aaacaggagt
    20521 agccaatttt tcgctcacac ccgctacatt aaaaaaagaa tacccattct taaaagaagt
    20581 agacagtctt gctttagcaa atgcacagct taatttggat cgggcttttc gcaattattt
    20641 caagggacgt gccagcttcc caaagcttaa aacgaaaaaa agtatgtggc aatcttatac
    20701 gaccaacaac caaacccgta cgatctatct ggaaaatggc tacttaaagt taccaaaaca
    20761 aaaagaacta atcaagataa atcagcatcg gccagttgaa ggatcgattc gctccgctac
    20821 gatttctgct cgatataatg aagaatttta tgtcgcacta ctttgtgatg tttcgccagt
    20881 aaaaaaagaa tctttagcta aatggatcgg gatcgcctat catccgaaga cattgatcca
    20941 aacatctcga cctctagaag taactttacc aaaatttcac cagacagaag aaaagctgca
    21001 acatgcacag cggaaattga atgtgaaagt ccgctccgct caccatagaa agatcaggtt
    21061 agatcaggca agcaattatc agaaacaaaa gagaaaagta atggatcttt atctgaaaca
    21121 aaagaaccag cgagaagatt atcttgaaca attatctggg aaattggtca aacaatatga
    21181 ctacttattt gtagaatctt ttccaaaaga agaggcacat gctgattttt ctattcacga
    21241 ctggcataaa ttaataacaa aattgcgtta taagtcccaa tggtataata aaaaatttct
    21301 tttgatcaat accgacggag cagaagaaag caattccgta agaaagagcc aagtagtaga
    21361 aaaaatgggc agacattcgg ttatcaaggg ataaaaaatg aatgaaactg ataggagcgt
    21421 tagggttagc cttgttaata aaaagtctta atgacttttg tttctaggaa tttttctttt
    21481 gaagaaaagc tcactaatta tgacaaacca ataaaacaat agcagaaaaa gttcgtacga
    21541 gctttttctg ctattgttaa ttttttattc agaaagttta cgaatacatc aaaattctga
    21601 aacaaaaaac gtaactcaca aagagttgtt tttgcgtttt ttcttgaatg attaggtctg
    21661 aatcttttgc tcacaacctt attcatggtg ccccggcttg agctgataga tttttgaagg
    21721 acggccgatt cctacaggac gttcaccgat ctcatcgaaa tattggagca tagctttctt
    21781 aaaattggaa tgatcgatcg ttttataatc gatccctaag aatttagcaa atacttttcg
    21841 agcttccgta atcgtgaaat ctttacctaa aacttgtaga acttgcggct cgtgttccat
    21901 tttattgact acacggttga atgctttcaa gatgatttga ctatggtcaa aagccaaagt
    21961 atctttgcca gaagactctc cagtgactaa atcaagcgag atagccactt ctccgctaga
    22021 taaatggatc ttgttactat gacgttctag tgtgaaccag cgtacttcct tggcatcatc
    22081 tccggcgatt agcggttctt ctccaataaa ggctaagtag ctgactgtga cgacccagcc
    22141 tcgcggatct cgattaggcg tactgaatgt atgcagttgc tcaatatttt cttttgaaat
    22201 aaccacacca gtttcttcct ttgtttctct taagacgctt tctccagttg actcatcctt
    22261 ttggacaaag ccaccaggca atgcccatga atttcgataa ggatgccctt ttctttggat
    22321 caacaaaact ttcagctgat cttcttcttt gttatagcac atcagtacga tatcgacagt
    22381 caaagagggc ttgtcatatt ctggacgttc ctgtttttga taccagttaa gaaattcttc
    22441 ttcacttgct ttatgttcat aatataattt ttcttcttct ttagaagcaa aacggttcat
    22501 ctgaccacct ccattgacag taaaagtact ttttacctta ttgtagcaga ctctgaaaaa
    22561 aaaccaagga tttacttgaa aaatctaggt tatcatttaa atatgaaaaa taaatggaag
    22621 tatgagattg aataaaaaga aaagcagata aaacggcaat actttatacc gctcttcacg
    22681 aatggcaaag aagccacaaa taacgatata tacgtcaatg ataaaacgca aaatccaagc
    22741 tgctgtcata aaactgttca aatgcccatg gaggttaaaa taaccataca tacgaatata
    22801 aaaatagctg aatattaaat gtgctaatga aagaaaagca atactaagtg taaaaaaaag
    22861 atgtttcttc tgcatgattg ttccagtccc ttactaagat agatagtctt tattatacca
    22921 cgtgtgaggg gagaaataaa aagccgtttt ttagtagata tgaaacaaaa caaaaacccg
    22981 catttattca acctattcat ccttttaaag gatagattga acgtagatag aagtcgttta
    23041 tccagtcttt ttcattttga aaaaaagcta acagcatgct ttttttatgg tatactagca
    23101 aggaaacgaa ttcgcatcat gcgataaagg aggaagagcc ccgtggcaga aaaggaaact
    23161 ttttatatca ctacgccaat ctattatcca agcggcaaac ttcatatcgg caactcgtat
    23221 actacgattg catgtgacgc aattgctcgt tataaacggt tgatgggctt tgatgtgttt
    23281 tatctcactg gagtggatga acatggtcaa aaaatcgaaa caaaagcaga agaactaggt
    23341 gtaaaaccgc aagaatatgt agataaaatg gcggctgatg tcaagaaatt atggaaaacg
    23401 cttgatatca gttatgataa attcattcgc acgacagatg attaccataa agcagctgtt
    23461 caaaaaatat ttgatcgttt attagaacag ggagatattt acttaggtga atatgaaggc
    23521 tggtactctg tttctgacga agaattcttt acagaaacac aacttgcaga agtgtacaaa
    23581 gatgacgaag gtaacgtgat cggtggtaaa gcgccaagtg gacacgaagt agaattggta
    23641 aaagaagaat catacttctt ccgcatgagc aaatacgcag accgtctatt ggaatactat
    23701 gaagaacatc ccgaattcat ccagccagaa tctcgtaaaa acgaaatgat caacaacttt
    23761 atcaaaccag gattagagga tcttgcagtt tcacgaacaa cttttacttg gggagtacca
    23821 gtcaagagtg atccgaaaca tgtggtgtat gtatggatcg atgcattatc caattatatt
    23881 actgcactag gatatggctc cgaagatgaa agtctattcg aaaaatactg gcctgcagat
    23941 gttcagatgg tcggtaaaga aatcgttcgc tttcatacga tctattggcc aatcatgctg
    24001 atggcccttg atttgcctct acctaaaaaa gtatttgggc atggctggct attgatgaaa
    24061 gacggaaaaa tgtctaaatc aaaaggaaat gtcgtttatc ctgaaatgct tgtggaacgt
    24121 tatggtttag atgcactccg ttattatttg cttcgtgctg ttccgtttgg gtcagatggt
    24181 gtctttacgc cagaagattt tgtttcccgt gtcaattatg atctggcaaa tgatctaggg
    24241 aacttattga atcgaacgat tgctatgatc aacaaatatt gtgatggact cgttcctgac
    24301 tatgcctcac ttgtcactcc atttgatagt gaactgtcta cgacggctgc taacgttgtc
    24361 ggacgttacc atgatgcaat ggaaaaaatg gaattcaata cagcattggc tgaaatctgg
    24421 gtgctgattt ctcgtgcaaa caaatacatt gatgaaacag aaccatgggt attagcaaaa
    24481 gacgaagaaa agaaagctga attgaatagt gtcatgatcc atttagctga atctttgcgt
    24541 atcgcagcga tattacttca gccaatcatg acagaaacgc cagagaagat cttcaatcaa
    24601 ctaggattgg actctgaaac aatgaatctt gaaggattac actttggcga atttccttca
    24661 ggaacaaaag tagttgcaaa aggtacacca atcttcccac gtttagatat ggaagaagaa
    24721 gttgctttta ttcaagaaaa aatgtctgaa ggtactcaaa caaacgaaga tacagtcaaa
    24781 tgggatccag aagaaacaga acttgtttca acgaaagaaa aacaaatcaa atttgatgta
    24841 tttgaaaaag tagaactaaa agtagcagaa gtcatcaact gtcaaaaagt agaaggggca
    24901 gataagttgc tgcaattccg actagatgct ggagacagcc aagaccgtca aatcttgtca
    24961 ggaatcgctg aattttatcc tgatccaagc gaattgatcg ggaaaaaagt cgtcattgta
    25021 gcaaatctga aaccacgaaa gatgcgtgga caaatcagtc aaggaatgat cctttctgca
    25081 gaagcaccag atggctcttt acaagtaatc gaagcaccaa aatccatgcc aaatggctca
    25141 gaaatcgcat agaaattcaa agggggtatg acactagttg tgtcataccc cctttttccg
    25201 aaatttgaga agcaattttc gtaaattcct tcttattact tgaagccaat catataatac
    25261 agaaacagag aactatccaa aataaatcct agaaaaagaa gtacgagctt cgctgatttt
    25321 tgttaattta gaataatact aataggaatc gtaaaaacag aaaaaaagca taatgataaa
    25381 gggtcgggca gattttaatt gattcatctg gtactctttt ttattgtcct tacattcata
    25441 aagtttgaat gcaatgactt tattacatct atatttatat ctaacagtag cgttgatgtg
    25501 ttaattataa gttctatcac tttatgttca attagtttgt gctcttatat gtgtgattga
    25561 aaatatagat aaaaaaacaa tcatcggctt tgacttcgat gattgttttc tttattttgt
    25621 aaaaatccta tcacttgatt ttatggtaac cttttatttt tgtcttcaaa cggcttggta
    25681 agagagcagt aagcagtgca aatgggatcg aaaagacata ccagaaaatc gtacgtccga
    25741 taccataatg ttgatagagc tttgtcaaca tcacgtgtaa caagatcaac cctaaaagca
    25801 aggagccagc tataaaccaa tgattatccc aatgcatgac ttcactaagt gccatcactc
    25861 caaaaggata gaaataaaaa tagatcccga ctaaggtcat ccgccagttc tttgtaaatg
    25921 ttccgatatt caataaaaag aaaatcgctg aaagcaaaat accgataggc ggaaaaagcc
    25981 caaccaaaaa ggaatacaac atcccccaca agatcatcac aggacctttg atcaatgcaa
    26041 cgattgcgat gaacaaagtc agcaatatta gtttttgtga taacgttgca acagtcatta
    26101 atccaaataa aattaatgtg aaccaatgcc aatgggactg ctgttgttct ttacgggaaa
    26161 aatcgacccg gttggataaa taatctgcta atttcggata agaacgctta aaatccataa
    26221 actgttcctc cttcgtggaa aaggtaggtt tagtatacga aaaataaaaa agaaatacat
    26281 ccgtcttaag agggagtttt tcactgaaag tggagaaaaa agaatggtaa attaaaatat
    26341 tctcagttat actgaaaatt ataccaaatt tcaaagaaga aagaggatgg gaatgaaagg
    26401 caaactaaaa cgagaaatca atctgtttgg cgcattagct accgttatgg gaaccgtgat
    26461 cggtgcaggc gtcttcttca aaactgctgc tgttactgct agtactcagt ctacaagttt
    26521 gacattgcta gcttggcttt tgggtggttt cttaacgatc tgtgctggat tgacagtggc
    26581 tgaattagct acagcaatcc cggaaactgg tggagctgta aaatatattg aagctgcgta
    26641 tggaaaattg cccagctttt tattaggatg ggcgcaaagc ttgatttact ttcctgctaa
    26701 tattgctgca ttatcgatta tctttgcgac acaattgacg aacttattac aattatctac
    26761 cgattatctt ttgttgattg cagtgatcac cgctgtttct gtgacagggt tgaatttgtt
    26821 agggacaaaa gtcggtgctt ctgtacaatc agtgacgttg attgttaaat taataccaat
    26881 tgctgtgatt gtcatatggg gattattgac cccaggacaa ggaactgtcc agttatttcc
    26941 aatcgaagct ggaaaagatg ttacttttgt cgaaggattg agcagtgcgt tgttagcaac
    27001 gttgtttgct tatgacggct ggttaggtgt cggtgcaatg gcaggggaaa tgaaacggcc
    27061 ggaaaaagat ttgcctaaag caattattct tggtttgagt tttgtaacag tcgtttatct
    27121 attgatcaat tttgtttttt tgaaaacttt gccgattgat catcttgccg gtaatttgaa
    27181 tgcagcttct gaagcatcag acgtcatttt tggaggaatc ggtggaaagc tggtcactat
    27241 tgggatcttg atctcggtat acggtgcatt gaacggttat acactaactg ggatccgcgt
    27301 gccttatgcg atggctttag aagacgagct acctttcagt aaacagctga caaagctttc
    27361 aaagaagttt acggttcctt atgttcctgc ggttttccag ttagcagtag cttgtattat
    27421 gatgagcctt ggttctttcg actttttaac agacatgttg atttttgtga tgtggctatt
    27481 cagtttactg atttttatcg gtgtctttat tttaagaaaa aaagcgccgg aattgccacg
    27541 tccatataaa gtaccacttt atccaatcgt tccgattatt gcgattctcg gtgctatttt
    27601 cattttaggt atgacgatga tgacgcaaac gaaattagca ttgatcggta taggtgttac
    27661 cttgataggt atcccagtct attatcaaaa aaagaaaaaa cgctcagaag agtaaaatat
    27721 ttcaacaaca gacagaaaaa gtacgaacta ggtcctctag atcttcgtgc tttttctatt
    27781 tcaataaaac aagttcttct attttgattt ttgctacttc tgcaagtagt gcttatgtgc
    27841 taaagtaaga atgaaaagga gagataaaca tgatatttga ttctcatacc catttaaatg
    27901 ctgaacagtt caatgaagat attccagaaa cgattcagcg agcacaagaa atgggggtaa
    27961 cgaaaatggc ggtcgtgggc ttcgatacgc caacgattga aaagtctttg caattaagcc
    28021 atgactatcc aaatatatac agtattatcg gctggcatcc gacagaggct ggcagttata
    28081 cgaaagaaat cgaaaataaa ttacaagaac aattgacttt accaaaggtt gtagcattag
    28141 gggaaattgg cttggattat cattggatgg aagacccgaa agaagtccaa gataaagtat
    28201 ttcgcagaca gattgctatc gcaaaagaaa tgaacctacc aatcagtatt catactagag
    28261 aagcacttga agacacgtat caaatcctaa aagaagaaga tgttcgagat atcggtggaa
    28321 tcatgcatag tttcagtggt gattatgaat gggcaaaacg atttcttgac ttagggatgc
    28381 atatttcatt tagcggtgtc gtcactttca aaaaagcatt agacgtccaa gaggctgcag
    28441 caaatgtacc aatcgaacga ttacttgtgg aaacagatgc cccttatctg gcaccagttc
    28501 cttttagagg aaagcgaaat gaaccaggct atactcgtta tacagtagaa aagattgctg
    28561 aacttcggaa tcttccgaca gaagaagtgg ctgcccaaac atggacaaat gcgcaccgat
    28621 tatttggtct aagcgaacat ggataagatg aagatccaag agattatagt cgttgaagga
    28681 aaagacgata caagaaggct gcgggaagta gttgatgcag atacgataga aacaataggg
    28741 tctgcaatca atgaagagat cctgatgcaa attgaacatg cccaagagac tcgtggagtg
    28801 atcgttttta ccgatcctga tttttcagga gaaaaaataa gaaaaatcat tatggaagct
    28861 gttcctcagg caaaacatgc ttttttgccg cgcacacaag ctaaaccaaa gaaaaaggga
    28921 agccttggtg tcgagcatgc aagtgatgct gctattttag aagcattgaa aaaggtcgtg
    28981 acgccagaca tttcccaaac ggctgtttct gaaatcacta gacaagacct tttagactat
    29041 ggtttaatag ctggggcaca agcaaaagaa aaacgagaaa aactaggtga cgagttgcgc
    29101 atcggttaca cgaacggcaa acaattggaa aaacgtttga agatgtttcg tattacgccg
    29161 aaagaactcg cccaagcaat gaaaatagtg gaggaacaac atgagtgaat atcgtgaaat
    29221 tgcgacaccc tctagaacaa aagagatttt attgaaacat ggtttttcat ttaaaaaaag
    29281 tttaggacaa aattttctga ctgaaccaaa tattttaagg aaaatcgtag aaactgcgca
    29341 aatagatgaa catacgaacg tgatcgaagt tggaccagga atcggtgcat tgacggaaca
    29401 attagccaag catgcaaaac aagtcgtagc atttgagatc gatgatcgtt tgatccctgt
    29461 attggctgat acgatgcaac cctatgacaa tgtgactatt gtacatcaag atattttaaa
    29521 gaccgatttg tcaacagctg ttagagaaac atttcatgag gagcttccgt taaaagtcgt
    29581 agcgaattta ccttactata ttacgacacc gatcatgatg cattttcttg aatcagattt
    29641 ggttgtggat gaactagtcg tcatgatgca aaaagaagta gctgatcgta tctctgctga
    29701 accaggaacg aaagcttatg gttcattatc gattgctgtt caatattata tggaagccag
    29761 tttagcattc atcgtaccaa aaacagtatt tgtccctcag ccaaatgtag attcagcgat
    29821 tttgaaactg acaagaagag atataccggc agtcgaagtg acagacgaaa aagcattttt
    29881 ccgattgaca aaagcggcat ttcagcaaag aagaaaaacg ctttggaata acttgcagca
    29941 ttcgtatggc aaagatgacc agacaaaagc atggttagca aaaagcttgg aaacagctgg
    30001 aatcgatcca aaacgtcgtg gggagacttt gtcattacaa gaattcgccg cattaagcaa
    30061 tgcgatgtca gaaaatatgc agtaaaaaaa gaggttgtga cagaagttgt gaaaaagctg
    30121 tcctgcatca agtaataaga acagccaaac aaaaatagtt cctcatgttt ttcgtttgtt
    30181 tgggcttatt accgcagatg caagcttttg aacaccgttt aagaaagagg ttgtgggcct
    30241 gccgtttaac tctaagtcac aaggaacaat ttcaaaaaac agcttctcat gtttttgagt
    30301 tagttggtct tattacttga tgcaagcttt tgaccactat tatgccgaac aaggagatgt
    30361 gacacaaatt ttgtcacatc tcctattttt gtttcttgat caaaaaattc ttatacttga
    30421 tactcacact cattttgtat ggatttagaa aagaatatgt gtcttgacag ttattagtaa
    30481 gtgagttata ctaagtcgac atttatgtgt caagacatat taggagagag aaaaaatgag
    30541 aaaaaattca gttcgaaaac taacgatttc tgctttattg attgggatgg gggtcattat
    30601 cccaatggtc atgcctaaaa tcatgattcc accagcttcc tttactttgg cgtctcatgt
    30661 gccattattt attgcgatgt tttttacacc aggagttgca gtggctgttg cgctaggtac
    30721 gacatttggt ttctttttaa caacgccggt tatcatcgca ttgcgagcat tgtcacatct
    30781 tgtgtttgcg ttgattgggg cttggtactt gcaaaagcat ccgagtatcg ttttaaaaaa
    30841 tggacagttt acttttgcta attggcgttt ccaagggttc aattttgtga tcggtgtgat
    30901 tcattcttta gcagaaatgc tagtagtcag catcttttac tttattggta atatgcctga
    30961 aacatattat tctcaaggat atttttatac agtattcatc ttgatgggga ttggtgggct
    31021 tatccacagt ttagttgatt ataatattgc ttattttata gcaggaacac tcagcaaata
    31081 ttttgatatc cccgtattta cggcagcaaa aaaagaaaat cggaaagagt cgattcaagg
    31141 gtacgcgaag aaaacgacat attagacatg atctctcaaa aaaaaaactc tcatctagta
    31201 atggataata aatcctctaa gatgagagtt ttttgtccta aaaagagctg caccaacatc
    31261 ttctggcaca gctctaacag ggggcaattt atggaagttt gatgacttgt tctgtttctt
    31321 tatcaaagaa gtggcctttg ctgatgttga aggcaaggtc gactatttcg cctggtttat
    31381 ggaaatctct tgcatctact tttgagatga actcagtaga accagttttt gtgtaaagca
    31441 tcgtttcagc tccaagtaat tcggaaacga caacttctga tttcactacg gcttcaggtg
    31501 aagcttcaag ggctacttgt tcactgtgga tgtcttctgg acgaataccg aagataactt
    31561 cttttccttc ataacctttt tcaactaata ctttgttttt tccttcagga atacgaagct
    31621 taagcccatg tccatctgtg ataacaccat ttttcaatgt cacattaaag aagttcatgg
    31681 caggagatcc aataaagccg gcaacgaaca tattgacggg tgtatcataa acttctttcg
    31741 gtgtaccgat ttgttggata aatccgtctt tcatgataac gattcggtca gccatagtca
    31801 ttgcttctgt ctgatcgtga gtaacataga tggtcgttgt ttcaagacgc tggtgaagtt
    31861 tggcaatctc agcacgcatg gctacacgta atttagcatc taaatttgat aatggctcat
    31921 ccattaagaa gacttttgca tcccgaacga ttgcccgtcc caatgccaca cgttggcgtt
    31981 gtccaccaga taaagcagct ggttttcgtt tcaagtattc tgtcagacct aagatctctg
    32041 ctgcattgtc cacacgtttt ttgatgtctg ctttatcata tttacgtaat ttcaagccaa
    32101 aagccatatt atcaaaaaca gtcatatgag gatacaatgc gtagttttgg aaaaccatgg
    32161 caatatcacg gtctttaggt gccacgtcat tcatgacttt tccgccgata tttagttctc
    32221 cttcagagat atcttccagt cccgcgatca ttcgcaaagt agttgacttt ccacaaccgg
    32281 aaggaccaac aaaaacgata aattcacggt ctttgattga tagattaaaa tcagttacag
    32341 aataattttc tgcattgtca tattttttat atacgttttt cagagccatt tctaccataa
    32401 tacgttccac actttctttt ttagttttat taactattta aagtataaat gaaagcgtta
    32461 actaacttca atgtcatgtt gaacaagaat tttttctttt ttttgtcaat gtgctagttt
    32521 taagctttaa taaatatcca taagaaataa aaactgatac actggagtaa ataagtatgt
    32581 taacaatatc aaaaggagtg tctcttatga aaatcgcttt gatcgctcat gaccgaaaaa
    32641 aacctatgat ggtgaaatta gcaacagcgt ataaaacaat attggaaaaa catgaacttt
    32701 ttgctaccgg gacgactggg cagaggatca cggaagcaac cggcttgccg atccatcggt
    32761 ttaaatccgg accgttaggc ggggatcagc aaattggagc catgatttcg gaggatcagt
    32821 tagatttggt gatttttctt cgagacccgc tggctgcaca gccccatgaa ccagatgtaa
    32881 cagcacttat ccgtttatct gatgtctatg agattccgtt agctacgaat atcggaacag
    32941 ctgaggtgct actaagagga ctggaagccg gcttcctaga ttttcgaaga atcgtccatg
    33001 aaatagacaa gcatccactt tcattttgat ggataagcgt atggaaaaat aacgtttaat
    33061 gttcgcctat atgtagctat aaaagctaaa caaactgata atatgcgata taatacgaac
    33121 gtattggata atataaacaa taatattagt ttttcgtatt tgcagtaaat gtgaaaatat
    33181 gctatagttt ctgtgggaaa agatcccaaa aataatacag agtagaaaat aaagcgttaa
    33241 gtgctaagag gatgggatgt tgcctcttgg acgaaggacg taatgttcgc ggttttattt
    33301 tcgcattcgc tgcatgatac gatgtagcag ctcttaaagg agatgctaaa aatgaagaaa
    33361 caccggttag acgcacgtat gattgctatt atgggcttat tgattgcatt gatggtcact
    33421 ttgtcccgac tggtagcaat cgagacccca tttattaaaa tcagtgtcac atttattcca
    33481 caagtgatca tgggcattct ttttggtcct ttttggtcag ggataggcgc agttttagct
    33541 gatttagtag gaatggccct cttctcgaaa tctgcattct ttattggatt tacattgaat
    33601 gcatttattg aaggagcaat ctacggattc tttttctatc gaaaagagat cacttggaaa
    33661 aatgccattc tggctacgct tagtgtcacg ctgatcatca acttattttt gacaccatta
    33721 tggcttgcgt tgatgtacca tgtgccattg ttcagctggg tcgtttgggc gccccgcctg
    33781 ttaaaaacag taatatggtt accgattcaa tcaattgcca tttattacgt aggacgtagt
    33841 attccttaca aaaaaatttt aagaagttta gcgatccacg ctaaataaaa aacaagcagt
    33901 cttcccatcc cagaagactg cttgttttta ttgtgctgtg aattgtgctt gatagagccg
    33961 tcggtaataa ccatcttttt gaagcagctc atcatgggtg cccatttcga caatagctcc
    34021 ctgatccatc actaatatct ggtccgcatt tttgattgtg gacaggcgat gggcaatcac
    34081 aaaactggtt tttccttcca tcattgctaa gaaggcttgt tggatttttt tctctgtcaa
    34141 tgtatcgact gagctggtag cttcatctaa gatcaacata gggggattac tgatcatcgt
    34201 tcgagcaatc gtcaacagtt ggcgttgtcc atctgatatc tttaaccctt gaccgccaat
    34261 cttagtatct aatttttccg gcaaacgttc tacaaattca tacatataag aggcttttag
    34321 ggcatcattg atttctgcgt cacttgcttc cggattccca aaacgaagat tttctcgcaa
    34381 tgtactgtca aatagccaag tatcttgtaa caccattcca aaacttttac gtaatgtatc
    34441 acgttggata gagcggatgt catggtcatc gactgtaatt gttccttttg ttgtgtcata
    34501 aaaacgcatc agcaaattaa caagtgtgga ttttccggcc cctgtttttc ctactatagc
    34561 aatggtttga cctggataag cagtaaaatt gaaatcttcg atcaaacgct gcttggggtc
    34621 ataagaaaaa gaaacatgat caaaagagac ttttcctttg atatttttgg gttccaaggc
    34681 ataggcatct ggcaaatcag gcttttcttc tggctgatcg atcaaatcaa atgctcgttc
    34741 tagaccagaa aaagcggttt gcagttgtgt cgtgattcca gaaagttcga taaatggttt
    34801 agaaaactga cttgagtaga tcgtaaagct ggaaatcaca ccaacagtga ttgacgaacc
    34861 actcttcaat gccaataggc cgccaactaa accaatcgat aaataagcaa ggtgatctac
    34921 aaaacgagaa gacgggtttg tcaaggaaga agaaaattgt gcccgttgtc ctttttcata
    34981 tagatcagca tttagcagtt caaattgctg ttgactagct tcttcttgct gaaaagcttt
    35041 cacgattttc tggttaccga ttcgttcggt cacaaagccc gagatatccc caataatcct
    35101 ttgctgtcta tcgaaatttg tttgtgaagc acgagcaacg atccaactca caaggaaaat
    35161 aattggtgta gaacaaagaa cgaccaatgt cagaagtgga cttagacgca tcataaaaat
    35221 aaacgaaaga atgatgattg ccactccaga aaataattga ttgaaggccg cagaaattgc
    35281 aatggaaata ttgtccatat catttgtaaa tcgactgacg atatttccgt gggagttttg
    35341 atcataataa cgaagtggca atcgattcag atgagcaaat gcatcttttc ttaattttgc
    35401 aacggataag taagctaacc gattgcttaa cacttggatg agccattgac tgactacgtt
    35461 gattaaaacg ataccaccga atagaataag taaatggaac agtcgattga agcggacctg
    35521 tccttctcca atcatttgat cgatactttg accaatttgt aacgtcatca caactgttgc
    35581 aatcccattg atgattccta gtatcacagc tagccaaatg tcttttgcat aggcagtaag
    35641 gtaaggaatg aatcggcgga gcgtctgcaa ggataatttt tttactttca taactattct
    35701 tcctcctgtg atgcgacgat ttcctgatat tctgctgatt gagcaagtaa ttcttcatgg
    35761 gtaccctgag cagcaatctt accttgatcc atcactaaga tatgatgtgc ttcttgaata
    35821 gagcggacac gttgggagat aataatcact gtactgccaa gataagtctg tagcgcctta
    35881 cgcaaatcca agtctgtttg ataatccaac gcacttaaag agtcatctaa aatcagtaat
    35941 gctggcttgg caatcaaagc tcttgcaatc gtcagtcgct gtttttgtcc gccagagaaa
    36001 tttttcccat tttccatgac ttttgtatct aaaccatttg gaagctgacg gacaaattct
    36061 tctgcctgag cgattttcag agcttcccaa cattcttttt ctgtggcgtc tttcttaccc
    36121 cattgaaggt tttcacgaat agtcccggta aatagtacag aagtttgggg aacaagagca
    36181 atttgctgac ggagatgatc cagctgccaa gaacgaacat ccattccgtc cattataact
    36241 gtaccggaac tgacatcata gaaacgcgga atcaattgtg tcaaagtcgt tttcccgctt
    36301 ccggttggac caatgattcc aaggactgta tttcgcttca gctgaaatgt aatattttgg
    36361 agagaaagac cagaatcagg agtataacgg aagtcaacat ggtcaaaagc gataattgct
    36421 tcagaagaaa aatcgggagt agtactgacc tcagcttcaa gaatcgaatt ttctgtgtct
    36481 agcacctctt tcacccgatt tcctgaagct tcggcacgtg tgaagatcac gacgaggttt
    36541 gaaacaacga tcagtgccaa aagcatttga ttcatataat tgatcaaagc aagaacttgt
    36601 ccttgttgca agctaccaat atttactttg atcccgccaa ctgtcagcaa acagatgatc
    36661 ccgacattca tgatcaaggt tgtagcaggt gataataggg cagagatatt ggaaacacgt
    36721 aaataattgt tcgctagatc atttgtgctt ttatcgaact tctctgtttc tttttttgtc
    36781 tgcgcaaatg cgcggatgac acgaacaccg ctaagattct gactaacgtg ttcattgagc
    36841 tgatctagtt tttcttgcac tttttggtag agaggaacgg tttttttgat gataaaaaat
    36901 aaaatgattg agaaaatagg caataatgct aagaaaaaca gacctacttc ccagtcgatc
    36961 acaaaagcca tgaccactga cccgatactt aaaaacggtg ctctgatcaa taaacgaatg
    37021 accattgcta aagctagctg aagctgattg atgtcgtttg tcattcgggt gatcaaggta
    37081 tctgttccaa aatgattcaa ctcgttgtga gagaaagtat tgattttttt gattagctga
    37141 ttacgtaact ctgtaccaaa tccttgtgaa gctactgaag catagtattg gcaaatgata
    37201 gcacaaatca gaccaatcac agacatagcg accatccata agcccatttc aatgattttt
    37261 cctcggtcat tcatttttag tccattatcg atcaaggaag ccatcattaa aggcaggaca
    37321 agttcgaaga cagcttcaag aaatttgaag aacgggccca aaatgatttg cttacgatag
    37381 tcttttgcat aacgtaataa ctgaatcata tgattcctcc tattatttat ttgtccacaa
    37441 ttgaaaaaac aagtactacc acattgtagc ttaggaaatt tagaatgaaa agagaacaag
    37501 ccttttcata aatgaaagtt ttattatgaa gaagctttag aaattgaata gactattttt
    37561 tttaaaaaaa agaaaatgag aaaacatgcc agtctcttca ttcataggaa cgtctatttt
    37621 acttaatttt tctataaatg aattctgcat aaaaaatata tcaagtaaat gtttatagat
    37681 gaaactctat ttacttcttt tttaatttgt tcttgcaatc ttttttgcta cgtaattttt
    37741 gtaaaaaagt gggttgagag aaatctaatt gattttcaaa gaaggagtat gaaaatgaga
    37801 aaaatattta ttcgtttatt gtgggtacta tcttagagga ataaataata gtggagaaaa
    37861 ctatggtttg gcgcagattc tatcaggttt gatggaacga agacaacctc ccgacatcaa
    37921 gtcaaaagct acttgagatt ttgatctgaa aataaaaaaa gaaaacaagg taggaacatc
    37981 aatgtttcta ccttgttttc gtaatcaatg ggaaaaaact aagagtggtg tacgtaatca
    38041 ataaaaagga tggtgacaac agtacctctt tactctctga aagcatcata actcgttttt
    38101 cctcattatg ccaataaatt gttgttatac cacatataag gatttgtaat agctaaaaac
    38161 agacaggaaa gttgaaatct gtgaatctta ttttgtatgg aaggatttat agaacgcaaa
    38221 aatcaagata aagatgaata aaaatcctgt ttcggctata tattgcgtat ctacgccaat
    38281 aaaacgagtt tgttctgtca tagccatata aagcaaaggc aaaaatacaa ctacagcgag
    38341 ataagatccg atgatttctc gaaaagtttt ccaggaagta tgtttcctgt ttttatattt
    38401 atccgatttc attgaatagt catagcctcc ttattctttc atatgttgaa attccagtat
    38461 aaaaactgga aggaactgta cgttttttag aataaaaatt ataagggata agtaggctgc
    38521 tgtctataat aagatatatt tttcaattct ttattaaaga ttttattgac aaaatgaatc
    38581 cgttttctat gatggaggag gggtgaataa gttgttgaag aaggaaattt tatgttactt
    38641 agagaaccag acagcctttt tcgatttaga acatatgaac gaggtcttta cagcacaaag
    38701 gttagctgat cattttgggg taaaaagaaa cacagtcagt cattatttga accagttaaa
    38761 tgatgagcaa ctactagtca aaatcaattc tcgaccagtg atttatttcc acaaagaagc
    38821 ttttgaaaaa caatttttta agttacgcac gaatttttat ttttctatcg atgatctcaa
    38881 agaggaacag ccttttttcg cgcaaccaaa agacttattc tcttttatga tcggatacga
    38941 cgccagtttg aaagaaagta tcgaacaaat caaaacagct ctttactatc cagatggcgg
    39001 attaccactt ttgattacag gcgaaagtgg cacaggtaaa agttatttag ttaatttggt
    39061 ctatcagtat tgtctgcttc atgatctgct agaagattct gcaccattca tcacttttaa
    39121 ttgtgcacaa tatgcagata atcctgaact tttgactagc aatttgtttg gacatgttaa
    39181 gggagcgtac actggtgcag aagaaaataa aaaaggggct tttgaagcag cagatggtgg
    39241 gatcttgttt ttagacgagg tacatcgctt aacaccagaa ggtcaggaaa aactgttcac
    39301 ctatcttgat caaggtgtga tttatcgtat gggagaacct aatttgtcac gccggatcaa
    39361 aacacgtctc ttttttgcta cgactgaaga gattactagt catttcttaa caactttcat
    39421 tcgaagaata cctatccgaa tcgaactacc tgcacttaat cagcgtagtc gtaatgaacg
    39481 gctagaactg atttactctt tttttctcga agaacaaaga aaaatgggga gccctttgtc
    39541 agtcagtgga ccagctttgt cacttttaac aagtcagaaa ttatccggaa acataggaga
    39601 gctgaaaaat atcgtcaaag tttcagcagc aaaagcatat gctgaacagc gtgaacagcc
    39661 tgaaatccat gtcacgatcc atcatttgca aaaagaacta cttgcgcagc ctattactaa
    39721 aaatacagca cagcaaggaa tctatattac gcaagaccag accttagagc aattaatgga
    39781 gaagcaacag cccgaacagc agcgaatcgt taaaagtttt gagcaaatcc taattgattt
    39841 caagaaaaat aactgtctgc tatattcttg cgaaggaaaa ttaaagcaag aagtgattca
    39901 attatttgat tttttgctgt ttgagaccag tagacaagaa aaacacgagc tgctggttta
    39961 ttggacacaa tctatccgag agacctttcg acaaatggaa actgcctatc aaatcaaatt
    40021 cgatggaaac agtgtctatg ccttgagtta ctatctctat cagcgaagca ctatcaaatg
    40081 gttaccggaa gaacatgata ttatccaact aatcaaagaa ttagaacaac aagtttctca
    40141 gtcttatcca tctagttatc actatgtcca acgaattctg gaattaagta agatcaaatt
    40201 agatattgaa gacacaagta tggatcggat tttactgacg atctatctaa aaaaagcgaa
    40261 atggtcaaaa gaaaaacgac tgccaaaagc gatgattgct gctcacggtt atgcaactgc
    40321 tagcagtatg gcaaatgtag taaatcgttt attacaagag gatctatttg aatcatttga
    40381 tatgccacta gatgtcacac cacagcagat tgcttcagaa atccttgatt attgcgaaaa
    40441 cagcgatgtt tcaaatggat tgatcatatt agtagacatg ggatctctga aagaaatcca
    40501 tcagtttttt aaaaaacagt tatccgtacc gcttttgatt ttgaataatg tgacgacacc
    40561 tttagcaatc acagtagggg aatgcctgca aaaaaatgta tcattagaag agatagcaga
    40621 agagactgtt cgacagatcc agccagaatg gcgactgctc tatccagagg aaaacaaacc
    40681 caaagcactc attactactt gcttcactgg aatcggtacg gcggtccact taagtgaact
    40741 gctagaaaaa agcttaccta cggcttgtca gttgaaaatc atcccatatg aatatcagca
    40801 attaaaagat aagaaaaaca gtgacccatt attttccata tacgaagtcg taggaatgat
    40861 tggcaccaca gatcctgata tcaccaatat cgactatctt tcattagaag acctcatctc
    40921 gggggaaaag atgtctgtac tagctgaatg gttggacact actatgaatg cttcagagaa
    40981 ggaaatattc aatcagcgca tcattcgtaa tttttcattg gaaaaagtac tggattccgt
    41041 gactattcta gatacagaga aggtgatggg agaaatcgat cattttatga gagaattaga
    41101 ggtgcagttg aatcgaagca tcagcaatcc caaaaaatta gcgttgtatg tccatgtgag
    41161 ctgtctcatt gaacgattga tccgacaaat gccaatcgaa acctatcaag gattagagaa
    41221 atggaagcag tgtcaaaaag aagggttatc tgctattaaa tctgcgttta gtgtcattga
    41281 agagcattat agtgtcatga tccccaattc tgagattgcc tatatctatg atattttgag
    41341 tgaagataca gagtttctct cgatagaaga agaattttga acataagcaa gttgttgcca
    41401 ctaattttgg catgcaactt gcttttttag tatgtgtaag tgaaaagagg agatgaaaaa
    41461 gtggatagag aaattatctt agcttcccat ggaaaatttg cttcagggat attagattca
    41521 ttagagctga tctatgggaa aaatcattct attactgtat tcgattgcta tactgatgag
    41581 aattttgatt tagcggaaac agtaaggcag ctttttatga ggtacaaaga taaagaaatc
    41641 attgttctga cggatctttt tggcggaagt gtcaacaacg aattcttaca atatatcaat
    41701 cgggatcatg tctatctcgt tgccggattg aatttgccac tattgattga gctagtatct
    41761 cggttggacg ctgaagtaga gacaactgtt ttgatccagc aggtgctaac tgattcaaaa
    41821 aaaatgatcc agttttgtaa cgagcggctc aatcagaaaa tagaagaaga cgaattttag
    41881 gaggaagaaa aatgattgta ttgacaagag tcgaccatcg gttattacac ggacaagtag
    41941 ctttttcatg gacacaaaca ataggcgcag actgtatttt gattgctaat gatgatgtac
    42001 ctacgaatga gatacgaaag acaacgatca aattagccaa gccacaagga gtcaaactag
    42061 tgatcaaatc aattgatgac tcgattgccg cgttgaaaag cggggtgaca gataaatata
    42121 agttattcat cgtagtggaa tcgatcgagg atgcatataa gctggcagaa gcgtatccag
    42181 aaatcaaaac catcaactta ggagggatca aggcaaaacc tggtactcgc agcatcggaa
    42241 aagcggtaaa tattttacca gaagaggagg aacgcttgaa acgattaatt gacaaacaaa
    42301 tagaagtaga aatccgtcaa gtaccagcag ataaaaaagt ggatgtaaga gaagttttgt
    42361 aagaaaggaa gaacctcaat gattgtacaa gcagtcttat taggaattgt tgcatttgtc
    42421 gcacaatcag aatatgcact agggacatcg ttgctttctc gtccgattgt gacggggctg
    42481 tttacaggaa tcgtgttagg tgatgtaaaa actgggatca ttatgggcgc aactttagag
    42541 ttagcattta tcggatcgtt ctcagtaggt gcttcgattc cacctgatgt tgtgaccggt
    42601 gggattttag ggacggcttt tgctattaca gctggagccg gtacagaaac cgcgctttta
    42661 ctaggtttgc cgattgctac gttgacattg atattgaaaa atatttactt agggcttttg
    42721 attccaatta tgaaccataa agcagacaat tatgcagaag aaggaaatta taaaggagtc
    42781 gagcatatgc acttgcttgc cggtatcggt ctttccttga tgcttggtgt tgtggtaatg
    42841 gtttcttata tggtgggaag caatacgatc ggaaatctat taaatatgat tcctgacttc
    42901 gttcaaaagg ggttgtcagt agctacaggg ttgattccag ctcttggttt tgcgatgctt
    42961 gctcgtttgc tgatcaacaa acaagttgca ccatattttt tcttaggttt tgctatagct
    43021 tcttacttag agattcctgt gaccggagta gctatttttg gtgcgatttt agcagttgtg
    43081 gtagtcaata ttatgaatgt ccgtcaacta ccacttcaaa caactgcagg ggaggtagaa
    43141 gaagatgaag aattctgaga tcaaaaacag caaaataacg aaaaaagagc taaatcacgt
    43201 attttggcgt tcttttcaaa tggagttttc ttggaattat gaacgtcaga tgaatatggc
    43261 ttatgtttat gcaatgattc cgattttgaa aaagttatat cagtcgaaag aagaaatggc
    43321 agcagctttg aaacggcatc tagagttttt taacacgacc ccacatatcg ttacactgat
    43381 tttaggaatc acggctgcaa tggaggaaga aaataaggat gatcctgaat ttgatgtgac
    43441 tgcgatcgat agtatcaaaa catctttgat gggacctctt gcagggttag gagattcttt
    43501 cttttgggga actttgcgat tgattgccac aggtgtgggt acctctttag ccatgcaagg
    43561 aaatatttta ggccctatct tgttcatttt gattttcaat attccgcaca ttctgtttcg
    43621 ctatctagca acaggttggg gatatcgctt aggaacgggt tttttgaaaa agatccaggc
    43681 aaacggtatg atggaaagtt tgacattagg cgcgtctatt attggactga tggtcgttgg
    43741 agcaatgact gccacgatga tcaccatcaa tattccttta aaaatcggtt caggagaaaa
    43801 tgctgtgact gttcaaagta tttttgatga tatcgttcca aatatcttat gtcttggagc
    43861 atttggcata gtgttttatc tattgaagaa agaagtgaaa ccattaacga tcttgatcgg
    43921 actagctttc tttggaattt ttggttcgtg gatagggatt ttttaaaaaa ggagcagaga
    43981 aaatgtttac gatgcaagat tatatctatg aagaaaagga agtactaagt acgatcttga
    44041 aaaagaatga tttttcgaca agagaacata tgaaaaaaac agtgaattta ctgatcttag
    44101 caacgggttc atcttataac gcttgtttag cagcgaagcc agcattggaa tcttatggtg
    44161 atcttactgt cgatattcaa gaaccttttt attttttcaa ttatggaaaa ctttctcctt
    44221 caatcgatac tgtgattgct gtgtcacaaa gcgggaaaag tgcttctact gttgaagcag
    44281 taaaaatgat acaaaaacaa gggttacctg ttgttgctat cacaaatgac gtgcaaagtc
    44341 cacttgcttt agaagctgca caaattattg atttaggtgc cggggtagaa tcagtaggct
    44401 tcgttacaaa aggctattct gcgactgttt tacagttact actcttaggg ataggaattg
    44461 gaataagtaa aaataaaatc agcaaaaaaa tagaacaaga ctacatgcaa cagttgcgca
    44521 aaataatcaa ccatttacca gcgattattc aaaaaacgga agaatttttt gatggatatc
    44581 aaagtttatt tcgtttagca cagcgtttcg tcaccattgg atatggtcca aactggggaa
    44641 cagctaaaga agcagagacg aaattgactg aaacaatccg cgttccgtca caaggatttg
    44701 agttagaagc ttatatgcac ggcccatacc tggaggcaga tgcttcgcat ttgctattct
    44761 ttattgaagg ggaaagtgta aataaggaac gttcgcaaaa gttgcaaaga tatatgagtc
    44821 ggtacgttgg agagactctc accattacca caaaaaaagc aagaaacgag aaaacacttg
    44881 gattagcaat agaatgtgat gaatatctgt ctgtattagc gcttgtcgtt ccgtttcaac
    44941 tattcgctta taaaaccgca gtagctaaag gtattgactt gaacaaaaag atttttgaag
    45001 actttgatac agtcttgaaa agtaaattat aagaggtgga aatcatgctg aaattcaatg
    45061 aagaagaaca aatcaaagca ataaaaggcg cactagcttt acgtccgcaa gtagaagaaa
    45121 tcatcgataa actttatgcg gaaaaatttg acgctgtcta ttatctagga atcggtggaa
    45181 cgtatgcttc ctcgatgcaa gctgtcactt atatgaatgg gaaaagcaac ttgcctgtct
    45241 ttgtacagca tgctgcagaa tattacacta ctggaaacaa aagattaaca aaagattcta
    45301 tcgttatttt gtcctctgtt accggtacaa ctcaagaagt agtgaaagca gtagaacaaa
    45361 tcaagaaagt aggagcgaca ctgattggat ttatcgataa agcgaacagt aagttgtctc
    45421 agctatgcga ttttgtggtc acttatccag ctcctggaac agaacaaatc aaatttttta
    45481 tggcagcaga tcgattgatg tatttgaatg gagaattcga agcttattca gaatactatg
    45541 aacagctcga acgttattta ccaacagggt tagtggaagc agagaaaaaa gcagatgcat
    45601 ttggcttatc atttgcagaa aaacatcgac gtgatagtat gcattatttt attggagcag
    45661 ggaatcaatg gggagctgtt tattcatatg ccatgtgtta ctgggaagaa caaagctggc
    45721 ttccatcgaa atctatccat gctgccgagt ttcttcacgg gacgttagag atcgtagaag
    45781 aaacaacccc agtcacatta tttttaggcg aagatgaaca gagagtgtta tctgaacgtg
    45841 tggctaaact tttgccaaaa atttgcagca attatacatt gatagacaca aaagactatc
    45901 cagtagaagg tatcagtgaa aaatatcgcg gacgtgtttt gtctttctta ttgatgcatg
    45961 tagtgacaca acgcatcgat gctcatgtgg agcagttgaa ctgccatcca ttagagatac
    46021 gccgctacta tcgtcagttt gattattagg atagactgga taaaaagaat ataaaaaata
    46081 aagagagcag cgataactgc tccctttatt tttttaaaat attggcatca attacgttat
    46141 aaaacaca
//
LOCUS       DARPZF010000016        44620 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.016, whole genome shotgun sequence.
ACCESSION   DARPZF010000016 DARPZF010000000
VERSION     DARPZF010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44620
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.016"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="SLE65_001225"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="SLE65_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEI8448531.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="SLE65_001226"
     CDS             complement(322..891)
                     /locus_tag="SLE65_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEI8448532.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="SLE65_001227"
     CDS             1077..1979
                     /locus_tag="SLE65_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEI8448533.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="SLE65_001228"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="SLE65_001228"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEI8448534.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="SLE65_001229"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="SLE65_001229"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEI8448535.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="SLE65_001230"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="SLE65_001230"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEI8448536.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="SLE65_001231"
     CDS             8547..8732
                     /locus_tag="SLE65_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HEI8448537.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="SLE65_001232"
     CDS             complement(8794..9990)
                     /locus_tag="SLE65_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEI8448538.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="SLE65_001233"
     CDS             complement(10160..11596)
                     /locus_tag="SLE65_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEI8448539.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11889..12698
                     /locus_tag="SLE65_001234"
     CDS             11889..12698
                     /locus_tag="SLE65_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEI8448540.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            complement(12884..15037)
                     /locus_tag="SLE65_001235"
     CDS             complement(12884..15037)
                     /locus_tag="SLE65_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEI8448541.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(15331..16179)
                     /locus_tag="SLE65_001236"
     CDS             complement(15331..16179)
                     /locus_tag="SLE65_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEI8448542.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(16403..18343)
                     /gene="thrS"
                     /locus_tag="SLE65_001237"
     CDS             complement(16403..18343)
                     /gene="thrS"
                     /locus_tag="SLE65_001237"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEI8448543.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(18680..18859)
                     /locus_tag="SLE65_001238"
     CDS             complement(18680..18859)
                     /locus_tag="SLE65_001238"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEI8448544.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(18906..20729)
                     /gene="cadA"
                     /locus_tag="SLE65_001239"
     CDS             complement(18906..20729)
                     /gene="cadA"
                     /locus_tag="SLE65_001239"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEI8448545.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            21007..23286
                     /locus_tag="SLE65_001240"
     CDS             21007..23286
                     /locus_tag="SLE65_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEI8448546.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(23379..24026)
                     /locus_tag="SLE65_001241"
     CDS             complement(23379..24026)
                     /locus_tag="SLE65_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448547.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(24205..24924)
                     /locus_tag="SLE65_001242"
     CDS             complement(24205..24924)
                     /locus_tag="SLE65_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8448548.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(25055..26206)
                     /locus_tag="SLE65_001243"
     CDS             complement(25055..26206)
                     /locus_tag="SLE65_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEI8448549.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(26423..27163)
                     /locus_tag="SLE65_001244"
     CDS             complement(26423..27163)
                     /locus_tag="SLE65_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEI8448550.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(27167..27490)
                     /gene="rsfS"
                     /locus_tag="SLE65_001245"
     CDS             complement(27167..27490)
                     /gene="rsfS"
                     /locus_tag="SLE65_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEI8448551.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(27547..28140)
                     /gene="yqeK"
                     /locus_tag="SLE65_001246"
     CDS             complement(27547..28140)
                     /gene="yqeK"
                     /locus_tag="SLE65_001246"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEI8448552.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(28124..28774)
                     /locus_tag="SLE65_001247"
     CDS             complement(28124..28774)
                     /locus_tag="SLE65_001247"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEI8448553.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(28784..29095)
                     /gene="yhbY"
                     /locus_tag="SLE65_001248"
     CDS             complement(28784..29095)
                     /gene="yhbY"
                     /locus_tag="SLE65_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEI8448554.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(29111..30220)
                     /gene="yqeH"
                     /locus_tag="SLE65_001249"
     CDS             complement(29111..30220)
                     /gene="yqeH"
                     /locus_tag="SLE65_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEI8448555.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(30217..30744)
                     /locus_tag="SLE65_001250"
     CDS             complement(30217..30744)
                     /locus_tag="SLE65_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEI8448556.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(30924..31709)
                     /locus_tag="SLE65_001251"
     CDS             complement(30924..31709)
                     /locus_tag="SLE65_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEI8448557.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(31702..32571)
                     /locus_tag="SLE65_001252"
     CDS             complement(31702..32571)
                     /locus_tag="SLE65_001252"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEI8448558.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(32572..33951)
                     /locus_tag="SLE65_001253"
     CDS             complement(32572..33951)
                     /locus_tag="SLE65_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEI8448559.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(33959..34378)
                     /gene="fabZ"
                     /locus_tag="SLE65_001254"
     CDS             complement(33959..34378)
                     /gene="fabZ"
                     /locus_tag="SLE65_001254"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEI8448560.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(34403..34879)
                     /gene="accB"
                     /locus_tag="SLE65_001255"
     CDS             complement(34403..34879)
                     /gene="accB"
                     /locus_tag="SLE65_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEI8448561.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(34882..36117)
                     /gene="fabF"
                     /locus_tag="SLE65_001256"
     CDS             complement(34882..36117)
                     /gene="fabF"
                     /locus_tag="SLE65_001256"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEI8448562.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(36136..36873)
                     /gene="fabG"
                     /locus_tag="SLE65_001257"
     CDS             complement(36136..36873)
                     /gene="fabG"
                     /locus_tag="SLE65_001257"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEI8448563.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(36885..37802)
                     /gene="fabD"
                     /locus_tag="SLE65_001258"
     CDS             complement(36885..37802)
                     /gene="fabD"
                     /locus_tag="SLE65_001258"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEI8448564.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(37909..38133)
                     /locus_tag="SLE65_001259"
     CDS             complement(37909..38133)
                     /locus_tag="SLE65_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEI8448565.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(38186..39148)
                     /locus_tag="SLE65_001260"
     CDS             complement(38186..39148)
                     /locus_tag="SLE65_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEI8448566.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(39158..39598)
                     /locus_tag="SLE65_001261"
     CDS             complement(39158..39598)
                     /locus_tag="SLE65_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEI8448567.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            39904..40869
                     /locus_tag="SLE65_001262"
     CDS             39904..40869
                     /locus_tag="SLE65_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEI8448568.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(40926..41156)
                     /locus_tag="SLE65_001263"
     CDS             complement(40926..41156)
                     /locus_tag="SLE65_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEI8448569.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(41242..42129)
                     /locus_tag="SLE65_001264"
     CDS             complement(41242..42129)
                     /locus_tag="SLE65_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEI8448570.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(42218..43441)
                     /locus_tag="SLE65_001265"
     CDS             complement(42218..43441)
                     /locus_tag="SLE65_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEI8448571.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(43458..44504)
                     /locus_tag="SLE65_001266"
     CDS             complement(43458..44504)
                     /locus_tag="SLE65_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEI8448572.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
BASE COUNT        12616 a         9650 c         7742 g        14612 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcat gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctagattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa
    11641 taataaaaaa taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt
    11701 tcattcgctt ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt
    11761 ttagcttatg tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat
    11821 tgctcttgtt aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag
    11881 gacccttatt gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag
    11941 attcgatgat tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc
    12001 atgtcagtat tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag
    12061 aattaacaac accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact
    12121 gggatggtga aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa
    12181 aaaagcagct aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca
    12241 gttttgattt ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc
    12301 tttctcctaa aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt
    12361 ttgcaggagc tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga
    12421 catggggtgg acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag
    12481 gcgtgcaaga gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg
    12541 acgagcataa tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg
    12601 gtactgacca actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg
    12661 gtttagctgt ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa
    12721 aagaggttgt gacaattttt gtcacaacct tttttgccga gtaaacggtg ttcaaaagcc
    12781 agtttctcgg tatgaagtca aatttaagca aaaatgtgag aagctatttt cacaaaattt
    12841 ttcttcatac tcgaaactaa gcggcttttt cacgacctct tttttatttt gccatgaaca
    12901 tatcataata cgcgtccatt atttctttag caatcgtcaa gtttatgtgg tcttgttcgt
    12961 ctaataagtt cggcaagaca acactgatgg caatttccgg attgtctgtt ggtccgtatg
    13021 ccacgatatt actattgact gtcgcaatat ctggatgacc ttccgcaacc gtttctgcag
    13081 tccctgtttt tgcggaaagg tccattttcg cactggctaa tggtttggct gttgtgtaag
    13141 gatcggtacc atggacaact tggtggaatc cttcacggag gatcgccata ttttctgcag
    13201 aaatattgac cgtattttct actgttgtgc caatttcttt cttcacttca cccaagtttc
    13261 cattttcgtc attgccatag atcgctttga ctaggtgcgg ctgtactcgt ttcccgccat
    13321 tagcgactgt tgaagcatat tgagctaatt ggattggtgt atatgtgtca aactgtccaa
    13381 atgccaaatc ggtaaagtta cctggagcat accattcttt gccattatcc gcattgaact
    13441 tcttcatata atcaacagaa cgtgagatcc caggagattc attcggcaaa tcgatcccag
    13501 tcgttgtacc aagaccaaac tctttgaaag agtctctcaa ttgctgataa gctttagctt
    13561 cttcatctaa actaggtagt cccattccag gtgtatagtc tagtcctaac atctttaacg
    13621 ccactttgat catatacgta ttagaagaca attccgatgc tttgactgca tcaagagcaa
    13681 cttgtccgct tcgattaaag acagagcttt tttctgaagc accttgcaga cgaatcggct
    13741 catcaatcaa aacttgattt ccgctgatcg cgttacttgc ccagcctgct gtcaaagtac
    13801 cagccttgac tacagaccct ggatcaaagg cgctagtaat cgtgcctaaa gcattctcgg
    13861 tgatttcttt ggaaccttgt tcatgactga aaccagtcat tgctagcact tctcctgtct
    13921 gaggattcat agccactgca taagcaccag gcgaatactg tgctttgccg ttgttgatca
    13981 atgtttgata attccttttc aaaatttctt ctacttttga ttggaattct gcattcatag
    14041 ataacattaa attagaacct ttttccccag agaagatttc tttttgattc gaaacatttc
    14101 cttcattatc aagggaaact tcatattggg ttttggttcc ttgcaggaca tcttcatatt
    14161 gtttttccaa ataactttgt cctacacggt cattccgaga ataacctttt gctaggtatt
    14221 tctctgcttc atctgctgga agtccttgct tttcagtcgt cacactgcca agaatacttt
    14281 tcagtgaact tgctgcatta tattctcgtg tccagtctgt gccagtcgaa actcctggaa
    14341 gttcagaagc gcgttctgcc acaacagcta actcttgatc agtaacacca gagtttttga
    14401 tatagacagt gtttaattca tatgcactat tcatccgttt aaagatggta gcaattttta
    14461 attgctcctc gtttaaatta atctcatcag ctgtgacttt attgaccatc gcactatatt
    14521 gttcgctgtt ccctaattgc ttttcttttg ccgaaagtct ttttgtggct tctttcaaat
    14581 gtttgggatc agccagccaa aaatcttttt tatctctatc tgtcagattt tcatctaccg
    14641 gaacatcgat cagcgagttc agcttcgttg cgatttcaag caaatcttta gccgtaactt
    14701 gtgttcctct cgtatatgtg atggcctgat tcgctttatt cgtaactaaa gcttttcctg
    14761 tggagtcgta gatcattccg cgaggagtac tttcttggac cgtaatcgta gaagtagact
    14821 tcactcgcgc ctccatctct tcgccgttca cgatctgcaa ataacccaat ctagcaatca
    14881 acgcaacaaa taacgtaaat ataatgaaaa aaagaaaatt taagcgaaaa ggaacatggg
    14941 accggcgaaa cgttttgttc ttaggttctt gtgcaccttt tcttattttt tctaaccaag
    15001 aagtatttaa tatttttttc ataaaatctt tcatcatttc ctatccttcc gcctatttac
    15061 attcatgctt cattgtaccc aaaaacttct taataaaaaa gaaaaaatgg gcggagcaag
    15121 aaattcttta cctaatttca agataaaatc aactttttgt ttcacagcaa tcacttaaag
    15181 ttacatatcc aactattttt ttcattaaaa aataaactta tttttgaaaa ttatgttttc
    15241 ttaagtcgtg aaacactttg atggatcatt tatttgtgga aaactacgtt ttgttattct
    15301 aaaaaactta tataaaaaat agtaaggttt ttatttcgaa tccataaaat attcttggat
    15361 tgcttctcgt gtttttttca ctttttcgct aagcttttcg tttttagcca tatagaaata
    15421 aaaaatgata tcgatcgtag caaattgggc caaaagtgaa ttagttgccg cacttcgatt
    15481 cgtgatttct tttggtctag atgtttgtac gagtacatcg gctatcttgc taagcgggtt
    15541 atttccaaat tgcgtcaacg caatgatttc gatattcatg cttttcgcca gctcggctaa
    15601 tgcgactaca tctgcacttc tacctgagtt tgaaacaagc caaagcactt tctttttctc
    15661 attgctgaca agttgcggga gcaagacgtg gatatctttt tcaaaaatga ttggcttacc
    15721 gacacgagac catttttgca gaatatcttc tactactaaa gaagaggcgc caaccccata
    15781 taaaaaaaca gtctctgccg attccaaaca ctctacgact ttttggatcg tttcttcttc
    15841 tagaatatct actgtttctt ttatcgctac ttgtgcattg ttaccaagtt tgtttttgat
    15901 agagtaaaag gactcatttg cttctatatc actaaaacct tcatcgattc cagtctgtag
    15961 ttctgttgaa atcgtgattt tgaagtccgt cagactttga aaaccgattt ttttggaaaa
    16021 acgtacaact gtcggcgcac tcaacccgga agcttctgct aattcattag ctgtcattgt
    16081 agggaccttc tcaatattac cgataatgta gttggccaac tttttttctg ctgaagaata
    16141 atcttccatc atactttcaa tacgactaat tacgctcata agttcctcca cccttttaat
    16201 gatagtctat gtaagtatac catatcagac ccttattcac ggtcgtatac tggataaaaa
    16261 acaaaaaaac aatccgccca acagaatatc ttatcccatc aatcccacag attctattga
    16321 gcatctgtgt ctttgaggaa tacctgttat ctattgttcg gattgctttc tatctactac
    16381 ttttttacag gaaatttacc tattagtttt ctctgctgta atttttgact tctgcttcca
    16441 tagcatcaat aaagatattc aaatcttcta cagctgtttc tttacttcca taacgacgta
    16501 cgttcactgt tgcatcttcc aattccttgt ctccaacaac taattggtaa gggatctttt
    16561 gtgtttgaga ggcacgtatc ttatagccca ttttttcatt acgatcatca acttctacac
    16621 gcaacccctt catttgcaaa cgttctttga tttcataagc ataatcgcca tgtgcatcaa
    16681 cagaaacagg gatgattgtt gcttgtatag gtgccaacca tgttggaaaa gcgcctttgt
    16741 atacttctgt taaataagcg acaaaacgtt ccattgtaga aacaattccg cggtggataa
    16801 ctactggacg atgcgtattt tccccgtctt ctccaacata tgtcaaatca aagcgctctg
    16861 gcaataagaa gtctaattgt atagttgata atgtttcttc tgtaccaaga gctgttttga
    16921 cttgaacatc tagttttggt ccgtaaaagg ctgcctcgcc ttctgcttca aagtaatcta
    16981 gttctaattc atccatagcg gctttcagca ttgcttgggc tttttcccac attgcgtcat
    17041 catcaaaata tttatctgta ttgtttggat cgcgatagct caagcggaaa cgataatctg
    17101 taatattgaa gtcagcatat actgccacca tcaattcaag cgtacgttta aattcatctt
    17161 tgatttgatc aggacgaaca aatgtatgac catcattcaa cgtcatttct cgtacacgtt
    17221 gtaaacctga caaagcacct gatttttcat agcgatgcat cattcctaat tcagcgatac
    17281 gaattggtaa ttcacgataa gaatggatcg tgtttttgta gaccatcatg tgatgagggc
    17341 agttcattgg gcgaagaaca agcatttcgc catctcccat atccattggc gggaacatgt
    17401 cttcttgata atgatcccag tgtccagatg ttttgtacaa ctcaacatct cccattattg
    17461 gtgtatatac atgttggtaa cctagactaa cttctttgtc tacgatataa cgttcgatcg
    17521 tgcgtcggat tgttgcccct tttggaagcc agaatggcaa accagaacct acttctgggg
    17581 aaaccatgaa caagtcaagt tcttttccta gtttacgatg gtctctttct tttgcttctt
    17641 cacggagacg gatatattct ttcaaagctt tcttgtcaaa aaaggctgtc ccgtatacac
    17701 gttgcatcat ttgattgttt gagtttccac gccaataagc acctgccact gataataatt
    17761 taaatacttg tatacggcca gtggatggaa catgtggtcc acgacacaaa tcgatgaatt
    17821 cgccttgttg ataagcagta atcacttctt cttctggcaa ttcactaatc agttctactt
    17881 tgtacggatc acttgcaaaa atttctaatg cttcctgttt tgaaagaaca cggcgttcga
    17941 tcggcagatt ttctttgacg attttcatca tttctgcttc gattgccggc aaatcttctg
    18001 cagttacttg gttttgtcca ttatctgtat cgtagtaaaa ccctgaatcg atagctggtc
    18061 caacgccaaa gtggatattt ggatagaggc gacgcatggc ttgggccatc aaatgagctg
    18121 ctgaatgacg gactaagcca agtgcatctt catggtctgg tgtgatgatc tcaatacttg
    18181 catcttcctc gattggacga gtcaaatcaa cgagttttcc gttcacttta ccagctaaag
    18241 ctttttttgc taagcttttt gaaatgcttt cagcaattgc caatgttgtt gttccagact
    18301 caaattcttt gactgcacca tctggaaaag taatttttat cataatagtt tcctccttga
    18361 aatgttttga ttgatcagat catcaagctg aaaaacaaaa aaatcctagc atctcttgaa
    18421 aagagatact aggacgaaaa gttcgtggtt ccacctaatg ttcaaacgca aatgcgttcc
    18481 tcaagcgttg taacggtccg accgcccttg cttcaacaag ggtttcgaaa gtggtcatcc
    18541 tttggttttc tcctggaaaa gtttcagcct agcttttcct ctcttatcga agactctcaa
    18601 attcagttgg ctttctcatc aatcaattat gtgtttattt aaccactaat aaatagaaaa
    18661 atcaagtggg aaactaaact tattttttcc attccccatt tacaccgtat gttccttttt
    18721 tcatctcatt gatgatgaca tggatgtgtt cttttggtgc ctgcgtgttt ttatgaacag
    18781 cttccgtgat atctttcatc atattttcta attgttccgg actgcgacct tctactaatt
    18841 cgacatgtac gaatggcata atgctctctc ctctttctga tcgttctttt ttcaactcga
    18901 ttctatcata ctatgtttgt cttgggtact gaatcaggaa aaatggctgg atcttttttt
    18961 gctctcaagg cactcaaaat agagaccgta tccacgactt cttgcaaaac agctccgaat
    19021 aatgcgggga ttagtcccgt acttgcaatt aacatcaaaa aaatacaaat aaagatgcca
    19081 atcagtacag actgtttcgc tattctcatc gtatctcttg aaatcactac tgcttttgct
    19141 acacgcaaga gatcatcttt caagatgacc gcatctgcac tttcactagc agctgtagaa
    19201 ccatgagccc ccattgcaat accgatatct gcagcagcaa gtgctggtgc gtcattcacg
    19261 ccgtctccta ccatcgcaac aggtctttga tctttaggga tactttctaa aatggtcagt
    19321 ttatcttgag gcaagctacg ggcatgtaca gaatctaatt ggactttttc tgcaatcgtt
    19381 tgagcaatgg cagatccatc cccggtgatc atcatcaaat ttttcacatc aagttttctt
    19441 agctccttga ttgtctttgc tgcttctggg cgaatctgat ccgaaaatag gatcgttcct
    19501 gcaaaagatc gatcaattgt tacatagatt gctgtattgg acgtttctat ttcttcagct
    19561 gaaacaaaag aggcacgtcc aatctttact tcatgattat tgactactgc ttggattcct
    19621 tgaccggtca cttctttcag ttgactaaca ggatacagtt ggctgttttt cacgttgttc
    19681 actaacgaac gagctaagat atggctagat tcctgttctg cactagctgc atacagaagt
    19741 agctcttctt tttttattcc attgactggc tgaatcgcct ctacttccaa tatccctttg
    19801 gtaagcgttc ctgttttatc aaaagcaatc gtttttgtac gtgcgagctt ttcaatcgtt
    19861 gttccagttt ttacaacgat cccgttttta cttgaacggc tcattcctgc aactaaagca
    19921 atgggcgcag ctagaatcag tggacaaggt gatgccacta ccagtacctc agcaaatcgt
    19981 aaagggtctt ttgagaacca ccaagaaata ccaccgatca aataagcaat caacgtgaaa
    20041 gggactgcat aacgatcagc taaacggaca aatcgggcag gcttttcttt tgattcttcg
    20101 actagtttaa taatcatttg atactggctg tctgcggcac gtttttcagc gatcatttgg
    20161 atcgatccgt ctccatttaa agaccctgac ataatctgat ctccaggttt cttggtttcc
    20221 gggcgggact cacctgtcaa agaagattca tcgaccgaag attctccttt ggtcactcga
    20281 ccatctgcgg gtacaagttc gccaggcttg actagtaact ggtcatcaat atttatttca
    20341 tcgattacta tatcctgcaa ttttccttct ttgaatcgat gggcaattct tggggtgtta
    20401 tctaacaaag actgcagttc tttacccgct cgtttattcg cgtaatcctc tagactatct
    20461 ccgcccgtaa gcatgatcaa tatcatcaaa ctagcccagt attctttgac ggctaatgtt
    20521 gcaaggattg cggtaatcgc taatacatct acgccatatc ttcctgaacg taacgtcttg
    20581 atcatttcca aaaacatcaa gaaggcgaga atccctccag taaatgcgac aatcgcaaat
    20641 gcaagggccg gctggtgaaa aacaaattca cttaataaag ctatcccacc aataagcaaa
    20701 gtaagtaaaa attttttgaa atgtgtcatt gttttttctc ctcttttatg tgacttagag
    20761 aggttagtaa taaatttcca gctgcctctt tcatcttaag catagtcctt gactagcact
    20821 ttttaaaaca ataggcctta attgaaaaca actatcacta tcagcgtttc caaaattcat
    20881 cagttctaca aacaaaaata ttcagcaagg attacttttt cgattcatca gttaaaaagt
    20941 accttttttc gaaaaactat gctatacttt taattcgtta tttacggcgg aaggagcaaa
    21001 catgcgatga atgagaaaca actagaacaa acgcacgtgg atgaaacgat cgaactaatc
    21061 cagatcgaac aaaatatgct ggatacaaaa caacaagaat tgactcagga aatgaatcat
    21121 tcgacaaaag acacagctaa tcacaagatt cgagctggtt ccaatgaagc tttttatgaa
    21181 tctgctgttg aatatcgcca acatgagcag gaattgcttt tgaaatacca tactcttgaa
    21241 gcacagcaaa aacgcctgca aacgttgtct gtcatgaaag atagtcctta ttttgcccgt
    21301 atcgacttta aagaagaccg tgaaacagaa acattatatc taggtatcgc ttctttaaga
    21361 gatctggcag aagaaacaat cgttattgac tggcgcgcac caattgccaa tctttattat
    21421 gaaggtgaga ttggtcccgc attttatgaa actgaaacag atagaataga tgtcgatctg
    21481 cagttgaaac gacaatttaa aatccaagaa ggacgtattt tatctatggt agatacgtcg
    21541 gaagtaatca atgatgactt tttgctagag atattggatg aatcatcaag caaccatatg
    21601 aaaaacatcg tctctacgat acaaaaagca caaaatgcaa tcattcggga cacaacaagt
    21661 aaagtaatgc tgattgaagg aatcgccgga agtggaaaga catccgcttt gcttcaacgt
    21721 attgcttttc tgttgtatca taatcgcaag tggctcgagg ctgaaaacgt tcttctattt
    21781 tcacccaacc atttgttttc tgattacatc tcgactgtat tgccttcatt aggtgaaagc
    21841 ggcgtgccta cacagacatt caaaaattat ttggtgcagc tgctgccaga gttttcttta
    21901 ctagatgaac agcaacaaga aagtggtttt ttgctagggg aaaaagatcc gatacaagtg
    21961 atgaaaagcg gattgacctt agtcgatcag attgatcgct atatccaagg catcacaaac
    22021 tacggtccct tgttccgtga tatgaaaata aatggccgta cgatcctatc aaaggaatcg
    22081 attcgccaat ggtataaaga aacaaatgaa caattacctt tacatcatag actttctcta
    22141 ttacaaacga agctcctgaa aaaattaggc ggtctgcaaa aagacgaaac acgtcagcaa
    22201 tgggtcaaag atctggcgga agaacagctc caagaactat acgcaacaga tccaaatctt
    22261 gaatatacag aacaaaagga gcgttcatta cgtaaaaaac tggccaacca aatcgtacgt
    22321 aaaagattcc gtcgaatcca tcgagggatc atgaattatc aatttgtcaa tataacgaaa
    22381 caatatctcc actttctaca aactgtgcca ctttctcttc taacacgaca taaaatcagc
    22441 gagaccaggt ggcaggaaca tttgacaact gttcgtacac acttgcgtca aagagaattg
    22501 cgtcaagagg atgctgtact attcttttta ctgatgcgcc gaacatatcc agtgacggtt
    22561 acacacaaag ctcgctatat ctttattgat gaaatgcagg atttcgcacc atcacaagtg
    22621 gcattgctgc aagccttgtt cccaaaagca aatttgactt tctgtggaga tctaaatcaa
    22681 aatgtctttg gaaatgaaac gatcgttgga tcattggaag accttttcgt ggaccgtgaa
    22741 gtcactcgtt tccaattaac gacaagctat cgctccacaa aagaaatcac tgattttgct
    22801 aatcatttta ttgtgaaaga acatcaagta gaaacaacag caagaaaagg agaccttcct
    22861 ttgctcatcc aaggaacaac agatgatatc aaattgaatt ggttagcaga taccattcga
    22921 acgactcagg gaaaagcccg gtattggcgt acagcaatca tagctaaaac acaagaagaa
    22981 tgcgaagctc tttatgctca actgccagac gagttgaaac aacaagtcca gctgatttta
    23041 aatgagagtg actttatgaa gcgttccatt attttacttc cagccttttt agcaaaaggt
    23101 ctggagtttg accgagtttt cttgtgggat gtagatgcag aacatttttc ttctcagcaa
    23161 gacaaattga tcctttacac catgtgtaca cgtgcgatgc atgaattgac cctttttacc
    23221 tccaataatg aaagtccttt gttaaacaat atggatattt catcttatga gaaaaaagta
    23281 ctgtaagtaa aaagacaact gctatcatta atgttagcag ttgtcttttt atttacaata
    23341 ataattgcag aaaaagtaat tcaatcattt aaggtcattt attctatata taaatccaaa
    23401 tctgtttcag gatattttaa tttgacaagc gaaataatca ttttcagttc ttccatgttt
    23461 tctggatatt ctgggtcaaa taccttgcta tgacggccaa tcccgccatt gtcgatcaat
    23521 cggtaaattc gattccattc aatgaattgg tcaattgatt ggaaattgct gattggatag
    23581 ccgccacaat ccaaaatctc tgatacacga aatgctaggt atgcactatc gatcacttta
    23641 ttttttttcg tgtctatctt ctcatttctt tcgataagaa ttttttcagg acgatgtttc
    23701 aagctccact ctaatagtag aaagaaagcc tccatccgat actcttcttc aaataaccga
    23761 aaggctgaat cagaacgacg aaaaagcagc ggaatcagat aattttgtct ataaatcagc
    23821 attggtgcgc ggtccaccat acactctaaa taacggttca gataccctgt accgacatag
    23881 tttcctaatc gatagccttc aacgccgaat cttgcgtatt tttgcgctaa ttttgaacaa
    23941 tcagttacgt tcacagctaa ctcttctact ttgcggtaac cgcttaagat acgttcaaaa
    24001 ggttctaaag tgatttttgc ttccatattc ttccccgtcc atcttccaca tacttcatat
    24061 catttcacat gatacttatg ctctcatcat accacaggtt gaattagaaa agaaaataaa
    24121 tcacacaaaa aagcaagaca atctgttagt gagattgtct tgcttttcga aaaagactga
    24181 atacttttcg ttaaaactgg ttgcttagtc ttctaatgcc acattatgga acacatgctg
    24241 tacatcttct agatcttcca gtgcatcaat cattttttca aatgtttctt gatcttctgg
    24301 agatagtgtt acctcgtttt gagggatcat ttggatctca gcgattgaaa aatcagtgat
    24361 tcctttttct tttaatgctt cttgtatact atggaaatcc gctacttcac cgtaaacgat
    24421 gatttgtcct tcttcttcca ttacatcgcg aacatcgatg tctttttcca ttaggtattc
    24481 aaggatctcg tcagcgtctt ctcctgcaaa agcaaagatt gctgtattgt caaacatgta
    24541 agaaaccgct ccggaaacac ccatgttccc gccatttttc ccaaatgctg cccgtacgtc
    24601 tgctgctgtt cgattcacat tgttcgtcaa tgtatcaaca atcaccattg agccgcttgg
    24661 tccaaatcct tcatagcgca attcagagta tgtttcatct cctgcacctt ttgctttttc
    24721 gattgctcgg tcaataatat gttttggtac attataagtt ttagcgcgat caatgacgaa
    24781 acgtagtttt tggtttgcat gcggatcagg atcacctgat tttgctgccg cgtagatttc
    24841 aatcccaaat tttgcataaa tccggctatt attagcatct ttagcagttt tctttgctac
    24901 gatatttgcc catttacgtc ccatattttc acttcgcttt ctgatttgat agtttcataa
    24961 cgcaaaaacg tcctgttcca ttatacttgt gaatcacgat tctgtgaagc tttttttctt
    25021 tcttccttca ttcttctcat ttttagtcaa ttatctatac tcggattggg atttgcccga
    25081 aattctgttc cggaatattg cctcccaatt gatagatttg atcacttcta actaacagtt
    25141 ccgcttcttg tgcctctttt tttccgattc gggaataaat agaaatctct tttttttctt
    25201 ttaagaatct tcttccagca tcggtaaatc caagtagtcg aagataattt ttattttgtt
    25261 ggacaggaat ctcttgcttt ttgatattca gcaagacata acaagataat cgttggatcc
    25321 gtgtccatgt atatcttttt gtttttacct ttgacacaaa atcctcaaaa ctatcagcag
    25381 ttgcagctgc tgttttcatg cgcgattcta ttccttcggt catctgatag atatctgtca
    25441 gttccagcaa agtagaagat aacaaccgat aacgcaaata cggccaataa gattcccaag
    25501 tctgcagcga acaagttgaa agatcttctt ctgtctgagg cggcacaagt ccagctattc
    25561 tttttccttc ttctaacgca tggcgaatgg ctgttgcact ggctatcctc tgatctgtga
    25621 tgattttttc atgatagcct gcacttttac gtcggatcgg atgtaattcc atagggtgga
    25681 catacttggc attttccttt gcataactta atcccaagat atgatttggc gaagaaaaat
    25741 caagcgtaat atcgggatac agactgcgaa aaacctcagt cattttttgc ggataactat
    25801 acgtttgatc agacagttct tgaaatgcct cttctatcct atcttgattc tcttggacaa
    25861 agcgtccgaa actgctgtaa tcaaacgaag tctcttcttc tgttccaaaa cacaaactgt
    25921 cacagtccag tgtttgcaag atttttactg cacctttagc aaaatagtca gctgactgaa
    25981 ccgcccattc gacgggaagc tccactacta aatccacacc attttgtaaa gcttcattcg
    26041 cgcgatgcca tttatcgatg atagccggtt cgcctctttg caaaaaattc ccgctcatta
    26101 cagcaatgac gacctctgct cctgttattt ttcgtgccat ttccacatga tagcgatgtc
    26161 cattgtgaaa aggattgtac tctacgataa tcccgcagct tttcatgcgc atcctccttc
    26221 atagttatcg ataaaaaaga aatagagaca agtaaaaaaa ggcaaaaatc ggaaaaaata
    26281 cccgaactat ataaactatt ctcgcaaaca caatacttct gcgacgaaaa gctgcactgc
    26341 aagagcaatg cctatatcgt tcggatatat aatttatgtt gaagatttat tcttttcttg
    26401 ttaactcgag caggcaaaac cgctagtctt tgtatgctac aaagaaccag cgctttgatt
    26461 tctctgatgc tgcttcgtct gtaaaatcag aaaatgcttc gactttcgaa aagccgctgt
    26521 tttccagcat tcttaaataa ctttccaatg gataggtacg ctcttgatgt agttcatctt
    26581 cacgaataaa tcgaccagac ccttcttgtt cttcaacgaa aaaggtaaga aaatgttcga
    26641 tgctgtgttt ctcgcttcct ggataactat cccacaaaaa agcaaaatta tccccttgat
    26701 aatgatagct atattctgga aaaacctcat ctacttgata ggtggagtgt acgtcaaata
    26761 aaaatcggcc attttcttct aacgcttgat agacttcatc aaacacttgc tgtacctctt
    26821 gtctattttt catatagcac agcgaatcag aaaaacaggt aattgcctga tattgtccga
    26881 tttctgataa atcgagcata ttgccttcca caaattggat cgatgcgtct tcttcatatg
    26941 ctcgctggct ggcaatcatc aacatctctt ctgaaaggtc taaccctgtc actttatatc
    27001 catcttttgc aaaggcaacc gctaatgctc cagtaccgca tgccagttcc aaaatatttt
    27061 ttgtgtcttc ttgtaaatga cgtttcgaaa aagctaacca ttgctgataa agtgtttcgt
    27121 ccatcacttc atcgtaaatg aaagcaaatg tttcataagc catatgttaa tccaaccatt
    27181 cactaagatc gactagcgga gcatctgacc atagtttttc cagattatag aaatttcgtt
    27241 ctggcgcatg gaaaacatgt acgatcacat ctccaagatc gatcaatacc cattttccgc
    27301 cttcttttcc ttcaatacgt tttacttcat atttgttttc ttcttcttta tcaatgattt
    27361 cttctgtaat tgcgttgatt tgacgttcgc tatttgctga acagatcatg aaataatctg
    27421 ccaacaagga aacatttcga acgtctaaag cgataatgtc ttctgcccgt tttgaatctg
    27481 ctgcttcaat cgcaattttt aattgttctt tactatctat gatgatttcc tcctaatatg
    27541 agcagcttat ttttttgcta cccagtaatt atatgtttcg attgtttttg gataaatctg
    27601 ttgttcttgc gcaagcaaat gggccaatgt atgttttgtt tcaaatgcta cagcttcgtc
    27661 tagatcagcc catgcaatgg ctcgtgcatc ttgtacccca ggaaaatctc gacctggttc
    27721 aatatagtct gctacataaa tgattttgtc aaggagactc atcttagcag ccccagtcgt
    27781 atgcacccgg attgcatgaa gaatctctgc atcggtgatt cctaattccc gctctacaaa
    27841 cgaagcgcca acaagaccat gccagattgc attattataa ttcaataact ccggatcaaa
    27901 accgtctctt acgattacca ttttgaactc ctcatctggt cgttcttttg cataatcatg
    27961 tgtcaatgca gcaatactag ctttttcagg agaagcaccg tattttttgg caagagccac
    28021 ggctgtttct tctactccaa gcacatgctt gaagcgttgt tcgctcattc tcatctgtat
    28081 tttttgcatc aggttttctc tagaataagc agtatattca ttactatagt ccatattcat
    28141 acaacccttc attttgaata taatcaatta ctttatctgg aacaaggtag cggatagaac
    28201 agccttcttt gatcttttga cgtattttcg tggaactgat gtcgatctca ggtacatcta
    28261 cccaaattac aggatatgga gtatccgttg tgtatcctgg tcgacgtata cccacaaagt
    28321 tgaccataga agtcagctca tcgattttat accattttgg caaatattct accatatccc
    28381 caccgataat aaagtaataa tctgtatccg gattgttttg cgtcaattcc ttcatagtat
    28441 cataggtgta acttttccca ccacgagcta attcaatcgt ttcaatctgc aaaaaaggat
    28501 tgtcttccac cgctaattcc aacatgttga gtcgatgttt tgcatcaatc gtctgtttct
    28561 catcaacatg aggtggctga taagaaggca tcaaaaatac gcggtcaaga cctaaattcc
    28621 ggccagcttg ttcagccatc actaaatgtg caaggtgaac gggattgaat gttccgccca
    28681 agatccctac ttgctttttc ttctctaaga attgaggcat ttcttcagga aataattgtg
    28741 aacgaacaaa tgtcttagct tgcgtattca tcatggtcac tccttatatt gcttttactt
    28801 cttttgatag cctttgatac ttttcttttg tggaaggttt gtataataca ataacacgtc
    28861 caatgatttg gacgatttcg caatctattt ctttttctaa tacttgagct gcttcttctg
    28921 caatctcatc tgtattttga agtaacgata ctttgatcag ttctcttttt tctaaagctt
    28981 cttcaatttg aacgatcatt gctgaattga tcccaccttt tccgatttga aaaatcggct
    29041 gaagatgatg cgctttgcta cgtaaaaaac gcttttgttt tcctcttaaa ctcataattt
    29101 tccttcttcc ttaaatcaat gctttgcgtt tcaatacatc tacacccttt ggcgcccagc
    29161 ccgcaattac tactggcgct gttacagtga tccagcctag accggcaaaa acgatgtctg
    29221 ttttttcttt cacagaaaac tcaaaacgaa caagctccgg aaatgcctcg acttcatcag
    29281 gacgaggagg ctgtaataat ccacctacat gtttttgata aaattcgtct gctttttcca
    29341 gtttcgttcg atgaatattt acatcatttg acacataagc aataaatgaa gcacgattgc
    29401 cgctgataaa atcaaatctt gcaagtccgc ccaagaaaag tgtttgccct tcattcagct
    29461 gataaacttt aggtttgatt tcttttaacg gtgcaatgat ccgcaaatct tttttaccta
    29521 agtagtgcgc catttgatgg cgatggataa ttcccggtgt atcaatcaaa aaatgcccgt
    29581 catctaaagg aatctcgatt ttatccaagg tcgttcctgg aaactgcgaa gttgtgatta
    29641 catcttgtac tcccgctgta tttttgatga tttgattgat aagcgtcgat tttccgacat
    29701 ttgttactcc gacgatatag acatcccgtc catcgcggta ttcttcgatt ttttctaata
    29761 gttccgtcat ctcatgagat ttcttagcac tagttaataa tacatctact ggacgaattc
    29821 ctgcttcgta agcacgttcc ttcatccatt gtgttaattt agtttttttc aatgatttag
    29881 gtaatatatc cactttgttc ccaactaaaa gtactggatt gtcaccgaca aaacggtgta
    29941 gtcctgggat tagtgaacca ttgaagtcaa aaatatccac cacattgacg atcaatgcat
    30001 ctttttgccc taattcattc agtaagcgca aaaagtcgtc atccgtcaat gagacatctt
    30061 gggtctcatt ataatggcgt aatctgaaac aacgctgaca atagacttcc ccggaagcta
    30121 aacctttttc caaagccgtt tgcggcgtgt atcctaattc accgggtttg tttgtttgta
    30181 taacggcacc acagccgata cattgtaatt cttctgtcat tcgattccac ctcgccagcc
    30241 catatcaggg tgttttgcta atagataggc cataattctt ttttcccaaa aacgattaaa
    30301 ttgtgtcttc caactatctg ttgcgataat gggttttaca aggatgctac gtatccctgc
    30361 acgattggct ccacgtatat cagtcataat ctgatcgcct accattacta tctcatcatc
    30421 tgctaaatcc aattgtttct ttgctatgtt gatccctctt gctaaaggtt tcattgctcg
    30481 tgcaacatac aaaagatcaa atttttcaat cgctcgcgcg acacgttttg aattattgtt
    30541 tgaaacaaca acaacaggga ttcctgcatt tttcatttct aaaatccaag taagcaactc
    30601 ttctgttcca tctggattat tccatgcaat caacgtattg tctaaatcgg tcaatactgc
    30661 tttgatgcct agattcttta attgggcagg tgtaatctga tagatggctt ctaccatcca
    30721 tgttggtttg taatttgaaa acatgctgtc tcctcatctg caaaaaatga aggagcacat
    30781 aaagtactcc tcaaccccgt attatactgc atatcagcaa aaaaaactac ctctatactc
    30841 gttcgtcttt cagaaaaagc atttctttac aaaatgacca aaaataaaga ttgatcacag
    30901 aaaaatttag aaacaaaaaa caactaatat tggcggaacc tcttgtatcg tttttccagt
    30961 aatttatgct gatctaatcg aacaagttcc gtcaatcttt caatcaacgc ttttttcata
    31021 atgtgtgcga ctttatatcg tggcaactgc tcgccgttga acgtttcagg aataactcga
    31081 tcaacgattc ctaactcgcg tagttctggc gcagtaattt tcatcaactc agctgcttct
    31141 gcggcgcgac taccgtcttt ccacaaaatc gacgcaaatc cttctggaga aagcacagca
    31201 taaatcgttt cttccagcat ccagacttca tccgctaaac ctagagcaag ggcaccgcca
    31261 cttccacctt caccaatgat gatggcgatg atcggtacct ttaaatcaga catttcgagc
    31321 agatttctgg caatagcctc tccttcgccg cgctcttctg ctcctacacc gcaatatgca
    31381 cctgctgtat tgatcaaggt aatcaccggt ctattgaact tttccgcttg tttcatcagt
    31441 cgtaaagctt ttcgatagcc ttcaggatgg ggagaaccaa aatttctgcg gatattttcc
    31501 tgcagatccc gtcctttttg aataccgatc actgttaccg gtttgccatc taatcgagcg
    31561 attccaccaa caatcgcttc gtcatctgca aataaacgat caccatggca ttcctcgaaa
    31621 gaatcgaaga tctcttcaaa aaaatccaag cttgtccatc gttctttagc tcttgctaac
    31681 tgaacgacat catgtgctgt cttatccacg atctatccat cctttctgtg tatgcaattc
    31741 aagaagcgta tggattttct gtttcaattc catgcgggga acaatctgat cgacaaaacc
    31801 atgagataat aagaattcag ccttttggaa atcttctgga agttcctgct tgatcgtctg
    31861 ttcgatgacg cgtcttccag caaaaccgat caagctttgg ggttctgcta gaataatatc
    31921 gccttccatt gcaaaactgg cagttactcc tccggtcgtc gggtccgtta aaacagttag
    31981 ataaaaaaga ccttcattgc tatgccgttt gacagcagca gagatttttg ccatctgcat
    32041 tagagaaaag attccttctt gcatccgtgc gccacctgaa gctgtgaaca agacgactgg
    32101 aagactttcc tttgttgctc gttcgaataa tctggtgatc ttttctccga caatcgttcc
    32161 catacttccc atgataaaat taggatccat cactccaata atgaagggaa tcccctgaat
    32221 ggttgcttta ccagtgagga ctgcttcatg aagtcctgtt ttatcttgca tttttttaat
    32281 tttttccgta tattcgggaa atgctagcgg atctttggtt acaagatccg tatcccattc
    32341 ttcaaaactt ttttcatcaa taatcaaagc tagacgctgc catgcaccga ttcgaaaagc
    32401 gtatccgcaa tgagggcata ctttttcttc accgatgtct ttcgtataaa ggatatgttt
    32461 gcaatttgga cactttgccc acatgttatc aggaacagat ggcgagttag caggtttgct
    32521 ctctctatta ggattgatcc gaatatattt ctttttctta aacagagcca tctatgcgcc
    32581 tcctatctcc gtttctggtg tccaattcgg taaaaattct tcttgtaaaa atgctgtgct
    32641 gtaatcacct gctatgactg caggatgact aatcaaatcc atctgaaatt ctgcgttcgt
    32701 gatgattcct tctgtgataa attcacttaa ggctcgctgc atcttcatta atgcttcaaa
    32761 acgcgtattt ccatggacga ttatttttgc aatcattgaa tcataatatg gcgggatcgt
    32821 atatcccggg taaactgcac tgtctactcg cagtcccatc ccacctgctg gaagcagtaa
    32881 gttttggatc ttccctggag aaggagcaaa atggaaagca ggattttctg cattaatccg
    32941 gcattcgatt gcgtgtcctt ggaatactac ttcttcttga cacacattca aaggctcacc
    33001 ggctgctatc tccacctgtt tttttactaa atcgattcct gtgaccattt ctgttactgg
    33061 atgttccact tggattcgag tattcatttc catgaaataa aaatcgcctt cttcatccat
    33121 cagaaactcg atcgttccgg cattttcata attgactgct ttagctgctc gaacagcagc
    33181 gtctcctagt gcttctcttt ttgtttgtga gatcactaca gaaggagatt cttccagtac
    33241 tttttgattg ttgcgttgta aagaacaatc tcgctcgcct aaatgaatga catgaccaaa
    33301 tcgatcacct aagatctgaa cttctatatg gcgagcagga taaatgattt tttccaaata
    33361 catatcatca tttccaaatg ccgctgctgc ttcttgctga gctgaagaaa aatgctgtgg
    33421 gagctcttct tttgattgaa ctttccgaat gcctttcccg ccaccacctg cagctgcttt
    33481 cagcatcact ggataaccaa ttctgtctgc tatttccaat gcttcttcta ctgtagataa
    33541 tacaccagta cttcctggaa tgactgggac atttgcttct tgcatcaatt gacgcgcatt
    33601 gatcttattt cccattgcat cgatcgttgc acttttagga ccaataaatg tgatattgca
    33661 ctcttcacac atggaggcaa atcggctatt ttcagataaa aaaccaaatc ctggatgaat
    33721 tgcttcggct tttgtcacga ttgcagcgct cagtacttcc tgaacattca gatatgaatc
    33781 aacggctttt gccgggccaa tgcagattgc ttcatctgct aactgtgtat gaagtgcttc
    33841 ggcatctgct tctgaatata tcgctacggt ttggatccct agttcgcggc atgcacgaat
    33901 gatacgtaca gcgatttcac cgcggttagc tatcaatact ttagaaaaca tatttcacct
    33961 atccaatcat aaaggttaat tccgcttcgg ctactttttt accgtctact ttagcgattc
    34021 ctttgcctat tccggctgaa gctttcactt tcaatatctc aacttcaagg tataaggtat
    34081 ctcccggtgt aactttctta cggaattttg ctttgtccaa tccgccgaaa taagccgtct
    34141 ttcccttgaa ttgttcaaga gaaagtaatg caactgctcc tgcttgagcc attgcttcaa
    34201 caatcaatac ccctggcata acaggttctt ctggaaaatg tccttgaaaa aagggctcat
    34261 tgatcgttac atttttctta gcaacgatcc gttctccttc aaccatttct tccactcgat
    34321 caatcaaaag cattggataa cgatgtggaa tgatttcttt tatttcttgt atgttcattg
    34381 ttttccctct ttcctgcttt gcttattttt gctgaatcct aaagagtggc tgtccatatt
    34441 cgacaactga ctcgttttct acaaggattt ctgtgatcac tccgtcggcc tcactagtta
    34501 tctcattcat cagtttcatc gcttcaataa tgcagataac ttctcctttg gcaacttgat
    34561 cacctacttt tttgaaagct ggtttgtcgg gcgctggttg cagataaacg attcccacga
    34621 ttggcgaaac aacctcgatt ccatcaaata ctgccgattc tttttctttc attatttctg
    34681 gagcagttgt tgcttgttca ggtatgacat tgactggctc cgaaactggc aacgtttcgt
    34741 ttgtttgaac catattcatg cctcgacttg ttttattttt attcatatac aattcaaatt
    34801 gaccttcacg caaatcgaat tccgttagcg aggattgatc aaattgactg actaattctc
    34861 tgatttcatt gatatccaaa attattcctc ccagcgtttc atgcacagaa ccgcattatg
    34921 tccgccaaac cctaatgaat tactcattgc ataagtaaaa cttgcaggtt tgctttcgtt
    34981 tttgacaact gtcaagtcaa tctcaggatc ttgtttttct acattgatcg taggtgggat
    35041 aaattgatgt tctaatgcca gcaaagttgc caaggcttcg atcccgccgg ctgctcccaa
    35101 taaatgtcca gtcatcgatt tcgtgctgct gacgtaagta tctctgaaat tttcacctaa
    35161 tgcgatttgg attgcttttg cttctgcctg gtcattggct ggtgtacttg ttccgtgagc
    35221 attgatatat ccgacttgtt ccggctgtac accagcttct tccatcgcaa gcttcattgc
    35281 tttagatgca ccagaaccat ctggagtagg agctgtcata tggtaagcgt cacagtttgc
    35341 accgtatcca acgatttctc catagatttt ggcaccgcga gcttgtgcat gttctaaaga
    35401 ttcaagaact agaacgcctg ctccttcacc catcacaaaa ccattccgat tttcgtcaaa
    35461 cggaatcgaa ccacgattag gatcagttga ttctgagagt gctgttaaag ctgcaaatcc
    35521 agcaatcccc atctcacaaa tcgttgcttc tgttcctcca gcaagaatga catcagaata
    35581 gccatgtttg atgttacgga atgcttcccc aattgaattc gttccgctag cacaagctgt
    35641 tacgatagct gtacaaatac cttttgcacc tacacgcaaa gcaatatttc cagctgccat
    35701 gttggcaatc gccattggta cgaacattgg agaaactcgt tttgcacctt tttcatgtag
    35761 acgaataact tggttttcga ttgttggaag accaccgatc ccagatccga tgatgacgcc
    35821 aaaccggtct tgattcattt tttctttatc taaaccgctc atctccattg cttctaaagc
    35881 agcgtagatt ccatagatcg aaaacatatc cattcgtttg ctatcttttt taataaaata
    35941 tttatcgtaa gggaaatctt tgacttcacc cgctaaggta atccctgttt ctgaagcatc
    36001 aaatttagtg atcggtgcga tgccattcgt cccctctttt aagctattca aaaagctgtc
    36061 tgcgtcattt ccaataggtg aagtgactcc atagccagta attaccactc gattcatttg
    36121 tttgctctcc ttttcttatc cgtgcatgac caatccgcca tcgacattga tgacttgtcc
    36181 ggtgatatat ggattttgtg ctaagaaaac tgctgtttgt gcaatatctt ctacttgtcc
    36241 gaaacgctgc atcggaattt gcttttccgc ttgttccttg actttgtctg ctaaaacttc
    36301 cgtcatatca gttgtgatga atcctggcgc aatggcatta catgtaatgc ctctagttgc
    36361 agcttctcgt gccacagatt ttgttaatcc tactacgcca gctttactag ctgcataatt
    36421 tgcttgacca atatttccaa tcaacccaga tacactagag agattaatga tggccccttc
    36481 tcgctgcttc atcatttttt tcaatacgtg ctgcgtcata ttgaaggttc caatcaaatt
    36541 gatatccaga cattttttga aatcttctgc atccattcgc atcacaagtt tgtcatttgt
    36601 gattccggca ttgtttacta acacatggat cgatccaagc ttttcttctg cttctttgat
    36661 catttgtccc gctttctcat aatcagagat gtcaccggaa actcctacgc attttacacc
    36721 gaatgcttcg atttcttcta tcttttcttt tggaatctct ccgcgaccat tcaaaatgat
    36781 atttgctcca gcttttgcaa aagctaaggc catcgctttg ccgattcctc ttgtactacc
    36841 tgtgataaat acattttttc cttttacatc cataacgttc ctccttatag tattgctatt
    36901 gtttcatcaa atgtctgctt attctcaaca cgcagaactg gtattgtttt atcgattttt
    36961 ttcataaatc cgcttaatac ttttccgggg ccgacttcga tgacttgttc gatgccgatt
    37021 gtttttaact tatggatact ctcatagaaa cgaacaggtt gcatgacttg ctgttcaagt
    37081 agtcccgcga ttgtttcttt cttcattatt tccgttgttg tgttgcttat gataggaaaa
    37141 gaaggttcag agaattgaat ctgacttagg tccttcgcca gtttttttgc tgccggttct
    37201 aaaatagctg tatgaaaagg cccgctgaca tttagaggga tcattctttt gaaccctttt
    37261 tcttttaata gtaaaacagc ttcgtctact gctttttctt cgccaccaat cacgatctgc
    37321 tgaggtgtat tataatttgc aggagatacg atgccgtact tgctagcttc atgacagctt
    37381 tcctcgatcg tttcaatcgg cgcattcatc actgcaacca ttttcccgct tccagctggg
    37441 gcagcttctg tcatataagc gcctcttttt gctactaacg caactgcttc agtgaaggat
    37501 agcgcattac tagctactaa tgccgaatat tctcctaaac tcagtcctaa agctgcatct
    37561 gggatgattc catgctcctt caataagcga taatacgcga tgctgactgt tagaatagct
    37621 ggctgtgtat attgcgtctg atccaaacgt tcattttctg taaagcaaag ttcagccata
    37681 tcgtagccga gaatctcact tgcttcatca aatgtctgct ttacaacggc ttcttcatat
    37741 aaatcttttc ccataccttg atattgtgca ccttggccac taaataagaa tgctgttttc
    37801 atgtttttct ccaatatatc cagaatatat gtttgattct tcctattcaa aaaggccgag
    37861 acattcctat ttcaggaaat gtcccagccc ccaacctaat tttaatgatt atgcagtttg
    37921 tttttctacg taagtcacta aatcttgaac cgttttgatt ccgtcttctg tttcgatttt
    37981 cacgtcaaat tcatcttcaa tttcattgat gatttggaat aaatccaagc tgtcagcttc
    38041 taagtcttct tggatgtcag tagtcaattt gatttcttca gtttcttttc ctaattcttc
    38101 tgcgatgatt tcttgaattt tttcgaatac cataataata tattcctccg atattgtttg
    38161 ctttttattt ttataattta acagtctaca actccatgag aatacttccc catgttaaac
    38221 ctccgccata gcctgtaaat attactttct gctgttttcc taaggtgatc tttccactag
    38281 aaactgcttc atccaataag atagggatgc ttgcagcaga tgtattccca tatttatcca
    38341 tattggtcag gaacttttct tgcggcatct ttacttttcg ggcaattttc tcaataattc
    38401 tgaggtttgc ctgatgcaaa agcagataat caactggttt gtctttcatg acttcttgga
    38461 tattgtttgc aacgtctcgt acggcaaaat caaaaatatc tctgccagtc atttgcaaat
    38521 aatacgaacc ttctgaatct tctgaataga acggattttt attttgctgg tagccagcgg
    38581 tcaatgagct acttctggta ccgtcagctg ctaatttttc tttcagcaat tttttctgtg
    38641 gattcgcttc taagagaatc ccacctgctc catcgccaaa caacacagca gtcgtacgat
    38701 cagaccaatc gattagctta gatagtgttt caccaccaat caccagtccc ttagttgagc
    38761 cgcagcggat cattttttca gccatgctta acgcataaac aaatcctgag cacgcagcac
    38821 tgatatcaaa agcgatagca tgagttgctc ccaatttccc ttgtacttgt gctgctacag
    38881 atggtgtcgt gtaatcgggc gacattgttg ctactaaaat aaaatccaaa tctttagggt
    38941 ttagattttt ctgttttatc aatttttccg ccactaaaat gcataaatca gaagtctcct
    39001 gatttgttac acatcttcgt tcacgaatac ccgtccttga cgaaatccat tcatcagagg
    39061 tatccatcat cttggaaaga tcattattag taataatctt ttcaggaagg acgctggctg
    39121 ttgcagtaat cattccaaat tgttccatta aatatcctca cttatagtct tgcaagaagt
    39181 cgtgcaagtt tttcagtgca tccagcaagg catgctgttc ctccgtagcc attccgtcta
    39241 agatgttctt gaccatttca cgatgaaaat gctgatggac ccgaaatagt aactttcctt
    39301 ttttcgttag tcccaacttt acaacgcggc ggtcatcttc actgcggata cgttcgacat
    39361 agcctttttt tactaacttg ttaatagcag tggtcaaggt cccaacagta attgatagtt
    39421 ctttggctac ttctgaagtt gtttttttct tgtacatccc gattgcctcg atcgtgtgca
    39481 tctctgtgat tgacagatct ttgaattgag attttttcag ctcagactct tcgattgtca
    39541 aaatatcatt gaagacacta acaagataat catttactgt ttttaaatct ggttccatgt
    39601 tccaccgtcc actaattagt ttgattatca aatcttttga tgttcaaact atatcttaac
    39661 ttttttcaaa atgcaacctt aaaagatcat ttttttacta tatgagcttt ttttaagatt
    39721 ttactcattt aaaacaactg ataaatcagc atttataatt tcttttatta gaaaaatcat
    39781 ctatctcaca tattttgatt atcaaagtat tttctgtgaa cagaactata gaattcccta
    39841 aaacttgtcc attatttcaa aatttgttat agtcttttta ttcaaagcgt aaaaggagat
    39901 cctatgttaa aagaaaaaat gaaaactctc cccatgctgc cgggtgtcta tcttatgaaa
    39961 gaccgagatg gtaaggtcat ctatgttggt aaagcaaaac ggctcaaaaa tagagtaagc
    40021 agctattttc atcagaataa acagcattca aaaaaagtat tacgtatgat tcatcatata
    40081 acagattttg atttcgtcgt agtagacacg gaattagatg ctttattgct cgagtgtcaa
    40141 ttgatccaac attaccgtcc tttttataac cgacaaatga attatttcag taattataat
    40201 tatgtacata ttaccaataa gggatttgta ttaacagata ctcctacggc tcgaacatac
    40261 gggccttttc gtctctataa aaaaatgccg tctattttgc gtataatgga agaaacttat
    40321 caaatgcctt ggttgtctga aattagtttg ttagctttgc gagtccagct tcctgaccta
    40381 caggaaatga cttttgaaca gaaaaaaaag gaactccaag ggctgtttca aggccgaaat
    40441 aaaaagctac tgacttactt gaaaaaaaga caacaacatt tcatctatca gttgaatttc
    40501 gaaaaagccg gtatgcttca aaaagatatc gaattagtta cttattttat tagacggatc
    40561 caggaacaaa agcagttttt aagaacacca tcgctcacct tcagcatgcc attagcagca
    40621 gatgagagtc agaaaaagca ctacctcgtt tgttatggtc aacttgcaga aacaatgatt
    40681 acctctggtg acgtttctcc tgacttctat tatgaaaaga aagaagctca tttatctttg
    40741 aaacgtcaat tgtcaaaaga agaaatcgat cctgtacaaa tcttgatcag ttaccgcaaa
    40801 aaattagaaa aagaacagtt tgaaattgaa ctgttaaaca aaaaagaagc tgaaaagcaa
    40861 ctaaattagt tgcttctcgg cttcttttag gcatcttcaa cttcaaatgt caattatcct
    40921 aaaatttatt ggattaagtc atagatttcc atcgctacga tatcgatatt atcaaattcg
    40981 tattgctgat gagtatctgt ttcagttaat tcaaatgtat cggtcgcttt atcataagtt
    41041 actgtacact tctctacgcc ttctttttca aaacggcgaa cttgcagttc attatctgct
    41101 gactcgacca tagcctccag tcgttttatg attgcgacta attgtgaatg tgtcatcgga
    41161 ggtcctcctt ttcttatttc tgttatattg tatcaaaagc atagcctact tgcattgatt
    41221 ttctctaaaa aaactcgttt tttatgattt tttttctggt atttttcctt caggccacca
    41281 aagtttgatc aaagcttggg ttccgtcatt ctcaaaacct ttatctgcca actcttcata
    41341 tagtttcaat gcttgggtag ttgctggcaa tacaagatcc attttttctg cttcttctaa
    41401 tgcaatcttt aaatctttga taaaatgttt gacaaaaaaa ccaggtgtgt aatcttcttt
    41461 taaaatacga ggagaataat tgcttaaaga ccagttagct gcacttccac ctgaaagcgt
    41521 ctcaatcact ttctttaaat caagtccgtt tttttgtgca tagacaagca tttccgtcat
    41581 tcctgtcatc gtacctgcaa tcatgatctg attagccatt tttgtatgct gacctttccc
    41641 agcagaacca tgcaatgtaa atgtcgtacc aaattctttg aataaaggca gtacttgatc
    41701 ataaacggct tcttctccac cgaccatgat cgtcagtgta ccattctttg ctcctaagtc
    41761 accaccggat accggtgcat ctaacgcatc tgcgcctttt tcttttgctg tttttgcaat
    41821 tttttctgcc aggcttggtg tacttgtagt caaatcaact aaaatatgtc ctgagatatc
    41881 tgcagaaaaa atccccgact gtccatagta gatttcttct acatctttgg ggtaacctac
    41941 cattgtaaag agaatattac tttgttctgc taccgctttt ggtgtatctg cccagatagc
    42001 tccttctgtt actaaaggat cagcttttgc ttttgtccga ttatagacag ctacttcgtg
    42061 tcctgcttct agtagatggc gtgcgacagc acttcccatg acgcctgttc cgataaaacc
    42121 aagtttcatt ttttcgacct cctaaaaatc aaaaatcctt gcttctatgc tagtatacgc
    42181 tagaaacaag gattttttca taaaaaatgt ttgaatttta tcttttaaat gaatttaatt
    42241 ttattttgat tcgttcaatc gagtcttctt cttcttttct tcgcatctct tcttcatgat
    42301 aaacaaccat gtcttgataa aattcgatca tagcttcgcc gaaatgtgta gatgaaatat
    42361 cataaagttt agcttctaaa acttttggat ctttaggaac ttcactggaa atataatcaa
    42421 taagtgctgg tgcaaagtct tcgtcggttt caaaagtttt ccctaatgaa ggatgatcga
    42481 acaatcggtt caaataagca tttccttcca cgacacaagg tgttccggct gccatcgctt
    42541 ctgtataagt aagcccttgt gtttctgaag tagaagcact gacaaaataa tctgccgctt
    42601 tataataaag tgctacatca ttgttgtcca cttctcctgt gaactgcaca aattcttcta
    42661 actgcagttc tgagatcaat tcctctaact cttctacata aggtcctttt cctacgataa
    42721 ctaatctggc gttaggataa gcggagatga cctgaggaaa cccattaatc aaggcttgga
    42781 tatttttctc ataagaaatc ctgcttaaag aaagaatcat caaatggttt tcctgaagac
    42841 ctagtgactc ccttaatttg ctgatatcct gctgagtgat atcagaacgt ttgaattttt
    42901 caatgtcgat accagtagga atcacgcgaa gcggtgctat tacaccatag ctgcgtaatg
    42961 tatcaataac acgttcactt ggacaaacta cacctgtcgt atgatttgca aataatctag
    43021 acaagtattt tacatgggat tgcctgatca cttttccttt accgatataa tgaaggtagt
    43081 cttcatacat cgtatggtaa gtatggatca gaggtatttt caacttctta gctaccatct
    43141 tcccaagtat ccctgctccg aattctgtat gggtatgaat aagatctagt tctagttctt
    43201 tggcaaccaa ataagcatac cacatgcctc taacaacaac tcttcgatcc ttgaaagaaa
    43261 taaatggtac acttggcatt cgaatcacat ctttttccaa cttatccgca ttaggatcgg
    43321 tcgttgtaaa aatatagact tcatgcccat gtctttctaa ttcttgtttt aatgttttga
    43381 tcgatgtagc aactccgctg acttgcggaa agtaggtatc ggtaaaaaag ccgattttca
    43441 tgtttttcgc ctccaaacta gtccttgacc tgatttactt tttttaattt gctagagact
    43501 ttttcattca gtacactttc gtatacattt ttaagttctt caccgatttt attgatactt
    43561 cgctcttttg ctgtttgata accggcttgt gtcgtactcg gtagttcttg attggtaatc
    43621 tgttggatca gtcggataaa ttcttcgttt gtcttcccca tatagcagtt cttgctatct
    43681 tctaaccagc cattatacac tggaatatct cgaacaagta cgttttgttt gcttgctaaa
    43741 gcttctaaaa caacgatccc ttctgtctct tcataagaag ggaaaaagaa tagatctgca
    43801 cctgaatacg caccttctat gatctctcca cgaatgtaac caggaaacag gacattttca
    43861 ggatgatctt cttttacaat tttccggatg ttccgaggaa tcgagtacat gggaacatga
    43921 ccaaaccaaa taaatgtgta ttcgggcatc ttcttagcaa tttctacgaa atcaatgatt
    43981 cctttacgtt cgaaaaacaa accgacacaa atgattactt tttgatccgg agacagtttg
    44041 aaatattctc tgaacttttg ttctttcatt ggatcagggt gatatttctc taagtcgatc
    44101 ccattggaaa tagcttgaat cggcacacgg ataccatagc tttccaacaa ctgttttgaa
    44161 taaggtgttg gcgtgatcag atagtccgct ttttggtaca atcctaccag atattttttt
    44221 acgataggag aaagctggtt cgatccgata aaggaatttc ggaaatcttc ctctgtagaa
    44281 tgcgcatgat agacaacttt ttttccttct cttctggctt tattgaccat attatgacta
    44341 ttgattccgt atgtattgat gtgcaggatg tcataatctt ctttttcatc tagtgtataa
    44401 gagataccga cttccgtcag agcacgtttt tgatgatcaa gcgcacgccc gattccagat
    44461 tttgcaagca tcttttcact ttcaaaatat aataatacct tcaccttacg tcccccttca
    44521 cttatatagt ataacatagc ctacaaactg tcactcaaac ttaagcccta tttttgtcta
    44581 ttcttactga caaaaacgtt ttcttaaaaa agaacaaaaa
//
LOCUS       DARPZF010000017        43149 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.017, whole genome shotgun sequence.
ACCESSION   DARPZF010000017 DARPZF010000000
VERSION     DARPZF010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43149
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.017"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            212..604
                     /locus_tag="SLE65_001267"
     CDS             212..604
                     /locus_tag="SLE65_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEI8448573.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="SLE65_001268"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="SLE65_001268"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEI8448574.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="SLE65_001269"
     CDS             3165..4775
                     /locus_tag="SLE65_001269"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEI8448575.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="SLE65_001270"
     CDS             5067..5936
                     /locus_tag="SLE65_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEI8448576.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="SLE65_001271"
     CDS             6101..7372
                     /locus_tag="SLE65_001271"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEI8448577.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="SLE65_001272"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="SLE65_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HEI8448578.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="SLE65_001273"
     CDS             8763..9026
                     /locus_tag="SLE65_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEI8448579.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="SLE65_001274"
     CDS             9471..9920
                     /locus_tag="SLE65_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEI8448580.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="SLE65_001275"
     CDS             9977..11395
                     /locus_tag="SLE65_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEI8448581.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="SLE65_001276"
     CDS             11395..12255
                     /locus_tag="SLE65_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HEI8448582.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="SLE65_001277"
     CDS             12429..13202
                     /locus_tag="SLE65_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEI8448583.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="SLE65_001278"
     CDS             13349..13714
                     /locus_tag="SLE65_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HEI8448584.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="SLE65_001279"
     CDS             complement(13862..15070)
                     /locus_tag="SLE65_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8448585.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="SLE65_001280"
     CDS             complement(15089..15367)
                     /locus_tag="SLE65_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448586.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="SLE65_001281"
     CDS             15521..16216
                     /locus_tag="SLE65_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEI8448587.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="SLE65_001282"
     CDS             complement(16658..17455)
                     /locus_tag="SLE65_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HEI8448588.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="SLE65_001283"
     CDS             complement(17452..18636)
                     /locus_tag="SLE65_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HEI8448589.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="SLE65_001284"
     CDS             complement(18661..19908)
                     /locus_tag="SLE65_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEI8448590.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="SLE65_001285"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="SLE65_001285"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEI8448591.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="SLE65_001286"
     CDS             21888..22202
                     /locus_tag="SLE65_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEI8448592.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="SLE65_001287"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="SLE65_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEI8448593.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="SLE65_001288"
     CDS             22887..23531
                     /locus_tag="SLE65_001288"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEI8448594.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="SLE65_001289"
     CDS             23546..23875
                     /locus_tag="SLE65_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HEI8448595.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="SLE65_001290"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="SLE65_001290"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEI8448596.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="SLE65_001291"
     CDS             24863..25687
                     /locus_tag="SLE65_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HEI8448597.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="SLE65_001292"
     CDS             25680..26027
                     /locus_tag="SLE65_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEI8448598.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="SLE65_001293"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="SLE65_001293"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEI8448599.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="SLE65_001294"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="SLE65_001294"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEI8448600.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="SLE65_001295"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="SLE65_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEI8448601.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="SLE65_001296"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="SLE65_001296"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEI8448602.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="SLE65_001297"
     CDS             31657..32451
                     /locus_tag="SLE65_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8448603.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="SLE65_001298"
     CDS             32441..34483
                     /locus_tag="SLE65_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8448604.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="SLE65_001299"
     CDS             34764..34913
                     /locus_tag="SLE65_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEI8448605.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="SLE65_001300"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="SLE65_001300"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEI8448606.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="SLE65_001301"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="SLE65_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEI8448607.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="SLE65_001302"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="SLE65_001302"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEI8448608.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="SLE65_001303"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="SLE65_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEI8448609.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="SLE65_001304"
     CDS             39330..40412
                     /locus_tag="SLE65_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEI8448610.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="SLE65_001305"
     CDS             40412..41215
                     /locus_tag="SLE65_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEI8448611.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="SLE65_001306"
     CDS             41285..42025
                     /locus_tag="SLE65_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEI8448612.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="SLE65_001307"
     CDS             42036..43040
                     /locus_tag="SLE65_001307"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEI8448613.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
BASE COUNT        13872 a         7535 c         9023 g        12719 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcgcgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg agcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatcttttt
//
LOCUS       DARPZF010000018        42886 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.018, whole genome shotgun sequence.
ACCESSION   DARPZF010000018 DARPZF010000000
VERSION     DARPZF010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42886
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.018"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            6..305
                     /locus_tag="SLE65_001308"
     CDS             6..305
                     /locus_tag="SLE65_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8448614.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="SLE65_001309"
     CDS             378..1739
                     /locus_tag="SLE65_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEI8448615.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="SLE65_001310"
     CDS             1761..2021
                     /locus_tag="SLE65_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448616.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="SLE65_001311"
     CDS             2035..2787
                     /locus_tag="SLE65_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HEI8448617.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="SLE65_001312"
     CDS             complement(2881..3486)
                     /locus_tag="SLE65_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEI8448618.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="SLE65_001313"
     CDS             complement(3539..4513)
                     /locus_tag="SLE65_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HEI8448619.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="SLE65_001314"
     CDS             complement(4891..5610)
                     /locus_tag="SLE65_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8448620.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="SLE65_001315"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="SLE65_001315"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEI8448621.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="SLE65_001316"
     CDS             7161..8558
                     /locus_tag="SLE65_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEI8448622.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="SLE65_001317"
     CDS             8639..9079
                     /locus_tag="SLE65_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEI8448623.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="SLE65_001318"
     CDS             9227..9553
                     /locus_tag="SLE65_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEI8448624.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="SLE65_001319"
     CDS             9554..10303
                     /locus_tag="SLE65_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448625.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="SLE65_001320"
     CDS             complement(10383..10838)
                     /locus_tag="SLE65_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEI8448626.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="SLE65_001321"
     CDS             complement(11265..11540)
                     /locus_tag="SLE65_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448627.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="SLE65_001322"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="SLE65_001322"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEI8448628.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="SLE65_001323"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="SLE65_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEI8448629.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="SLE65_001324"
     CDS             14770..17436
                     /locus_tag="SLE65_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEI8448630.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="SLE65_001325"
     CDS             17800..18552
                     /locus_tag="SLE65_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEI8448631.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="SLE65_001326"
     CDS             complement(18574..19728)
                     /locus_tag="SLE65_001326"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEI8448632.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..22354
                     /locus_tag="SLE65_001327"
     CDS             19913..22354
                     /locus_tag="SLE65_001327"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEI8448633.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(22684..23388)
                     /locus_tag="SLE65_001328"
     CDS             complement(22684..23388)
                     /locus_tag="SLE65_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448634.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(23575..23820)
                     /locus_tag="SLE65_001329"
     CDS             complement(23575..23820)
                     /locus_tag="SLE65_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448635.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(23837..24688)
                     /locus_tag="SLE65_001330"
     CDS             complement(23837..24688)
                     /locus_tag="SLE65_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEI8448636.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            24854..25858
                     /locus_tag="SLE65_001331"
     CDS             24854..25858
                     /locus_tag="SLE65_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEI8448637.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(26099..26455)
                     /locus_tag="SLE65_001332"
     CDS             complement(26099..26455)
                     /locus_tag="SLE65_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEI8448638.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            26823..28010
                     /gene="tuf"
                     /locus_tag="SLE65_001333"
     CDS             26823..28010
                     /gene="tuf"
                     /locus_tag="SLE65_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEI8448639.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(28198..30789)
                     /gene="mprF"
                     /locus_tag="SLE65_001334"
     CDS             complement(28198..30789)
                     /gene="mprF"
                     /locus_tag="SLE65_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HEI8448640.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(30815..31576)
                     /locus_tag="SLE65_001335"
     CDS             complement(30815..31576)
                     /locus_tag="SLE65_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEI8448641.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            31854..32375
                     /locus_tag="SLE65_001336"
     CDS             31854..32375
                     /locus_tag="SLE65_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEI8448642.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            32434..33294
                     /locus_tag="SLE65_001337"
     CDS             32434..33294
                     /locus_tag="SLE65_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEI8448643.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            33479..35794
                     /locus_tag="SLE65_001338"
     CDS             33479..35794
                     /locus_tag="SLE65_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEI8448644.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            35976..37817
                     /locus_tag="SLE65_001339"
     CDS             35976..37817
                     /locus_tag="SLE65_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEI8448645.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            37841..38950
                     /gene="rpoD"
                     /locus_tag="SLE65_001340"
     CDS             37841..38950
                     /gene="rpoD"
                     /locus_tag="SLE65_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEI8448646.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            39170..41269
                     /locus_tag="SLE65_001341"
     CDS             39170..41269
                     /locus_tag="SLE65_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HEI8448647.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            41465..42328
                     /locus_tag="SLE65_001342"
     CDS             41465..42328
                     /locus_tag="SLE65_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEI8448648.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            42433..>42886
                     /locus_tag="SLE65_001343"
     CDS             42433..>42886
                     /locus_tag="SLE65_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HEI8448649.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKE"
BASE COUNT        14096 a         7511 c         8868 g        12411 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagccg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
    21121 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
    21181 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
    21241 agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca atggcaagaa
    21301 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
    21361 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
    21421 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
    21481 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
    21541 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
    21601 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
    21661 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
    21721 tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct tagggagaaa
    21781 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
    21841 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
    21901 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct acgcggcaag
    21961 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
    22021 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
    22081 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
    22141 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
    22201 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
    22261 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
    22321 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
    22381 gcaagattta cagttatttt atttactgca gatcttgctt ttttctctat cagaaaatat
    22441 gtttattatt agaatttttt atagttaagg ttaggcatct taagaaatca ggcaactcca
    22501 agatatcttc aggtagaaga gaagtcgcct aacattgtag gatcataggt gatttgttgg
    22561 acaggtcaag ctgatatttg agcctgatgt tagaaggaat ttctttttac ttgctgtaga
    22621 aattattata tgactaaaaa ggctgggatt ttaaatccca gccttttatg acaaatagaa
    22681 tttttatcga tcagtaatcg ctgtcgctgc aaattgttcg atcaaaggaa tcaaagtcaa
    22741 tttgactttg tatttccgtt cgagtgcttt ttcgataacg aactcatttt cagtagtcat
    22801 agaaatagtt gctaatttac gaggttcatc agcatttttt tcattaataa ctacttcatg
    22861 ttcattttgt tctgtgtaaa atttaggata ctcagcaacg gcttttgaaa aatcagcaaa
    22921 acttaaagcg gcattcgtat cagttgagcg tgtattttca gttgtgtccg cttttggttt
    22981 ttccgttttt tcttctggca cactgactgt ttcttctgta actggtgtcg caacagcttg
    23041 cgcagttggt tcatcgtttt tcaatcgttg atcattccag taagacacga tttcaataag
    23101 aagattgtca cggaatcgtt cgaaaatccc gttttctcct gaacgaattc tctttaatac
    23161 agtattgaag ttgtcatcga ttggcacgtt gatccgtgta tcttcatttg ttttcccagc
    23221 taatccgatc gttaagattt gacggttttt gggatcaagc atgacttgta acggcaaacc
    23281 ataacgtcgc aagctctctt cttctagaga acggaataat tgtcctctta caccatccaa
    23341 tgaaggacgg aattgattta ataatttttg tttctgtttt ttcttcatat gttctctcct
    23401 tcgctcatac cctttcgatt ataagaaaaa aacagccaaa tgaaaaggag taatgcaaaa
    23461 aaacttgcgt atacgcaaat tacaacagaa aaatttgcgt attttcccgt tttttgaaag
    23521 aaaaataaaa aatggaacgg attatgtata tatacataat ccgttccatt ctttctattt
    23581 tttcggtatc aaggcaaaaa caggtagttc aggtgaataa atgacttcat gttcgtgcca
    23641 gggtttgacc attagcgaat gatcgaaccg ttttttcagt tcttcgatga tttgatcatg
    23701 tgtccagttt cttgcaggaa aatgttggat tttctctgca tcgatcaaaa agacaaaatc
    23761 ggaatgaaaa gtctgggtaa cttcttccga gagagaattc aagcgttcga ttggatccat
    23821 aaaatcacct ttcgacttaa aattgggtag tatctgggtc ttttgctttg ccgactacac
    23881 catctaactg atcgatttgt ttcatttctt cttctgttaa ttcaaaatca aataattcag
    23941 tattttcttt gattctgctt ggtgtcactg acttaggaag aggaaggaat tcgtgttgca
    24001 gcgaccaacg caaagcaact tgtgcaatcg tcttgtcatg tgcttcagcg atttgtttca
    24061 tttcaggcac atcgaagatt ttaccagtgc ctaatggact atatgcttcg aggatcatat
    24121 catgtttttt tgcatactca actacagttg tctgtaattc gcctggtgca aggaaaactt
    24181 gattgaccat cggcataatt tttgctgttt ttgctagtgt atctagatgg tggggtaaga
    24241 aattgctcac accgattgct ttgattttac ctgcttcata cagttcttca aatgctcgcc
    24301 atgtatctgc atttgcttgt tcccaattat cacgaaaagc aacagggttt ggccagtgga
    24361 tcaaaaacag atctaaataa tctgtttgga gcttcttcaa tgattcttca aaagaagaca
    24421 tcacaagttc atagctgtgg tttgcattcc ataattttgt tgtcaagaat atctcttctc
    24481 taggaattcc actttcctta atcgcttggc cgacgctttc ttcattcttg tatccttggg
    24541 cagtatcgat atggcgataa cctgcagcca gcgcttcttt aacagaggaa acagcgacat
    24601 ccccatcagg tgtttgccat gtgccgaatc ctactaccgg gatttcgtaa ccatttgata
    24661 gacgataagt gcttgttaat gaattcatac tttcagctcc ttttttattc gttcaactat
    24721 aagtgtagcg catttttcga aaaaaagaat ccattttgtt tctactcttg aaatttttgt
    24781 ttaaaagaaa atgattttga ttctggtatt tttgattttt tttccgtaaa ctaagacaga
    24841 agggaatgag aaaatggata tctatttaaa aaaagcaatt ctgcatatta ttgacagaga
    24901 aactggttct ccagtctttt cacaaaaaga gctggatctg acaaaagaat atattcgtga
    24961 ttttcttcaa aagaagatcc aaaaaatctc ttctgctcaa acaaaaactg gacaactagc
    25021 agaagaaagc atgatcgttg aatcacttaa aatcgctcaa gaaaattttg tggaagcaag
    25081 tgaagcaatc gttcagcggt ggttcgatat ctaccaagaa agtgaagaag cacctagtgc
    25141 agatgtattt gttgtcttgt atgaattaga tacagtgatg tacttatctt tattgaaagt
    25201 caattatcgt gaggcttaca ctcactttgt tgaagcagac gaagcaggga tcgacaaccg
    25261 cttgattttg aatcgagcaa ttctaggggc gaaaacacaa aaagcagatg aagcattcgc
    25321 tgtgaatttg actgattgga cctacgaatt aattgaaaaa aaatatgagt tttctggcaa
    25381 aaaagagctt tatttttctg gaagagtgat cgaaagtgtt cctgcacctt ctttagaaga
    25441 aaatgtaaaa gtgatccaaa aagtagccaa gcatcttgga aaaaaatttg agacagaaga
    25501 atttgatatc atggctgatt tgaaagaagc tgtctatgat acgatagaag aaaaaggtcg
    25561 gttggatcat gagatgattg cggaaaaagt cttcaaggaa aacatcacgg caaaaatggc
    25621 ttttaaagaa gaagtacaag agcaaggatt tgtcccagaa gcacctcctg taaaagaagt
    25681 acaagaaatt tctgagaaaa aatttggaaa acaaaaattc aagctatcaa acgggatcga
    25741 actgatcgta ccagtagatg tatatcgcaa cccagatttg attgaatttg tgaataatcc
    25801 ggatggtacg atatccgtga tgatcaaaaa tgtggatgaa gtattgaatc gtttataaaa
    25861 atgactagaa tattaggtgt tcaagtacca gtgatcagtt aaatgaattg tgtcaagaga
    25921 aggatcggaa aagacgaata taacaaaaaa agagcgtgag acaaaagtaa agaacacttt
    25981 tgtctcacgc tctaaacacg tataaacggc ggaagcagaa gcaactcctt cttatttctt
    26041 ggagttaaac gcttctgtcc cagcctcttt ttatctaata aaattttaag accatttact
    26101 aattatcgat tttttctgcc gcatttttag gcacttcaga agcctttatt tcttcccagc
    26161 ttaatacacc tttacgagga ttgactttga gtttaagata cgcattcatc tttaatggat
    26221 gttctctttc ttcgcgaagc gtcacctgtt ttttttcacc atctttatta taagccgctt
    26281 gcttgtaggt ataagtcgtg aatttctctc cgttatctgc ttgggtagct gacatttcgc
    26341 cattcgtcgt gatttttgta taataagctt cgccgccgta aaaataatga taagctgcaa
    26401 aacttccgcc gagaaatatg cctaaaacga caagtacgcc aattaatttt ttcatgtact
    26461 tcacctcttt ccttattatt aacgaaatag aagatttcgt ctattgaaag ttgttggcaa
    26521 cagctgaatt ttaaactttt cctcattttg ttcttattgc ttcaaaagaa agttaaggac
    26581 tatcttgaag tttttctcaa aaaacacatt tttttattta taaaaggtac ttttttcgcg
    26641 tataagacag acgagtgctc ttagttgact ttgaccaata ttgacgtata ataagcttag
    26701 ttcgaatctt acaaaaagta agtcggacgt attctttttg atttagtcaa aaaaagacta
    26761 taataaaaag gtgagagctg aaatttttca gtgatctata ttatttagga ggtttgtaaa
    26821 ttatggcaaa agaacattat gacagaagta aaccacacgt taacattggt acgattggac
    26881 acgttgacca tgggaaaact actttaactg ctgcgatcac tacagtatta ggcaaaaaag
    26941 gcctagcaaa tcctcaagac tatgctagta ttgatgcagc tccagaagaa cgtgaacgtg
    27001 ggattacgat caataccgca cacgtagaat atgaaacaga aaaacgccac tacgcgcata
    27061 ttgatgcacc aggacacgcg gactatgtga aaaacatgat tacaggggca gcacaaatgg
    27121 atggtgcaat cttagttgtt tctgcaactg acggtccgat gcctcaaaca cgtgaacaca
    27181 ttttattgtc acgccaagtt ggtgtaaaat acctgattgt tttcttgaac aaagttgatt
    27241 tagtcgatga tgaagaattg atcgatttgg tagaaatgga agttcgcgag ttattgagcg
    27301 aatatggttt cccaggcgat gacactcctg tgatcaaagg ttccgcatta aaagcattgc
    27361 aaggcgatcc agatgctgaa gctgctatta tggaattgat ggatacagta gatgaatata
    27421 tcccaacacc agaacgtgat acagataaac cattactatt gccagtggaa gacgtcttct
    27481 caattacagg tcgaggaact gttgcctcag gtcgtattga tcgtggtgct gttcgtgtcg
    27541 gtgatgaggt agagatcgta gggatcaaac ctgaaacaca aaaagcagtt gtaacaggtg
    27601 tagaaatgtt ccgtaaaacg ttagattacg gggaagctgg ggataacgta ggcgtgttgt
    27661 tacgggggat ccaacgtgac gatatcgaac gtggacaagt acttgctaaa ccaggttcca
    27721 ttactccaca tacaaaattc aaagcagaag tgtacgtgtt gacaaaagaa gaaggtggac
    27781 gtcatactcc attcttcaac aactatcgtc cacagttcta cttccgcaca actgatgtta
    27841 caggaacaat cacattgcca gaagatacag aaatggtcat gcctggtgac aacgtgacga
    27901 ttgatgttga cttgatccat ccaatcgctg ttgaaaacgg aacgacattc tcaattcgtg
    27961 aaggcggacg gacagtaggt tcaggtatcg ttacagagat cgaagcataa gaaacgcgac
    28021 tcgaatattt tggtaatgaa aaatgtttaa aataaaagag cggtccaaac aggatttctg
    28081 tttggaccgc tctttgttct tcaattgtat aagaagagat tgtagaagca tgaactttcg
    28141 ttttacttca gtctctttta ttcatcatga gagtgttcat ctatcggtat gcagttttta
    28201 atactttctt cgtatccatt ttttcaaacc acttattcta ccttgtgtct gctcaactgg
    28261 cgcattatca ataatcagca aagcaatcat aacatatgca atccaactat ctctagaata
    28321 tagagtataa cgtgagaccc agtttgtagc gtacttgctt ttatattctc ttaatccatg
    28381 gaaagaataa aaatgagaac caaactcgta aaccaagtat gcaatccttt cctgtaaaaa
    28441 actctttctg gaagttccga catttgaaag aggggccatc cctaaattga accattggat
    28501 atgttcttct ttcatatagg caaacaaatg caagaacaag aaatccatac tgccagaagg
    28561 tgctttttta gaatcatatc gcatcagatc aatcgttcct actttattgt tcgtgtaagt
    28621 aggcatgatc gttgcaaaag cgacaatttc ttcttgggta tttttgacaa ctgcaatagg
    28681 cgctctttgt agataatctt cagagaaaaa gcctaaagaa aacccttttt cctttcgtga
    28741 acccaaccaa ttatcagaga tatttttgaa agtactcatt tgctcagtag aaaatggtgg
    28801 ttgtaagaca tcaaatgtaa atccttctcg ttcgatccga ttcaagacag cacgagtgcc
    28861 cttcattttt ttccctgaag ttgtaaaact attcaggtct acataagctt cttcccccat
    28921 cttaatgaaa tcgtagccga attcatgcaa aatcataaca atctcttcgc ttgtttcgta
    28981 gaaaactggt aaatagcata gtcgatctgt ttcttcgata aaagcttcga ttgcttctgg
    29041 aaaatcttct ttcttaccag aaggatcacc cattacaata catttattat tgaagcaagc
    29101 gaattggaga agaacagttg gttcaccgtc tttttcatag gcaaacatcc gcttatcttt
    29161 taagaagatc aattgactat cggagtttcc tccataagtt gtaaggatct tcagggcctt
    29221 ttcttcatta aaggcttcgc caatctgttt cttttctcct tgaaggaaat gaacaaatag
    29281 aacgatcatg aaactaacag cgatgatggc caacaatccc gaaaaccaaa tcttttcaga
    29341 aggaaataag aaaaaggaaa taaaatggtg acgccgatga gggaaatccg gcagattgta
    29401 taccccaata acgatgtaaa gcaaggacag tgcaccaata atgattccat cgatcgtacg
    29461 ccactcccat gaatagatca attgttcccg aaataattcg tttttagaag caagaatgat
    29521 cagaagcaga atagacaaga aaaccaccgg tgtgaaacta aaatcactta ataaaacata
    29581 aagtaaagct agaacaatca agaagattgt aggcaaatat gctcgtttca cacgtgctgc
    29641 gatccctctg cccataatga ttaaaagaaa tcccaatagt atactaggaa attggataat
    29701 aaaatgaaat ttcaatgggt tcaaactatg aagccagcga aactctgtaa aagcttgcgg
    29761 gatagtggca gaaagtacta gcatgattcc agaaaagtat aataagacaa ccacgatttt
    29821 atgcgcaatt tctgttgcta attgtttagg gataccagaa taacgctgat caaaagtgga
    29881 accgatattt ttgaagaaaa agacgattcc aatcaaaaac ggaatgatgt agtagaacag
    29941 gcgatagagc aagatccaca caacgactat ttctcttggc acaccaatag cggacaaccc
    30001 gataatcatc attacatcga aactcccaat ttctcctgga atcatagaca cgattcctat
    30061 cactgaagca gcaatgaata atggaattgt ttgccacaga tcaatccgga tttccattaa
    30121 ataaccaaca gaaaggaaac taaacaggac accggtccat tccaacaatg aaactagcaa
    30181 tagctgtcct tgagttttaa gtgaggtacc accaaggaat cctttctttt tgaaagtagt
    30241 aaataaaaag acgacaggaa aatatagacc gccgccgatc aaccatatcc aatattgctt
    30301 caaaaaagga gcaactggcg tgaagactac aagtaaaaaa gaaagcagac tgtaaataga
    30361 aagtccagcc atcaaaaaca agaaaacttt cgataatgct tggatcacgt ttctgctctc
    30421 tttcttttgt ccatatagtt cagagcgaag ccccacacta acaaacccgc cgaaaccggc
    30481 aatattgttg atcgtattga tcagccagct tgtctcaaac aggtaacgag gattctgctt
    30541 ttgttcaagc atccgattca aaataatatc ataaccaacc ataggtaaca cagagataag
    30601 accaatcaat agcattagtc cgcttttcca tacaggtata gtggcaaacg tttctcctaa
    30661 ttgctggata gatagagttt taccgatgga catcaattca ccgacaataa tgacaatgac
    30721 agaaatcaaa aagattgttt tgaacagtcc taggtggttt ttcagccatt gtatggtatt
    30781 ttttaacaaa taaatcacct tctattccta atagttatgt ttcagaaaga aattgaagaa
    30841 cttctcgatt gaagcgttca ggatcttttc tagctaattc atgtccttgt tctttcacaa
    30901 gcacaaagga agcttttggt atagttttag ctatatacaa agaatgtttt agcttgatta
    30961 catctttttt tcccacgatg atcaaagtgg gggagttgat tttttttaaa tcattttctg
    31021 taagcccgat gtcatgcagc aaaagtttga taactaaaag atttttgcga agacttgggc
    31081 gaaataaaga gagtaaccat acccatgcat aatgaatatt actgatgact ctggcagaaa
    31141 aacgaacgcc tttaacaagc gtgtttccag aatttaaaat caatcgatga acttttttag
    31201 ggaagctgct ggcaaatacc agtgctagat ttgctccatc actaaatcca agaaaatctg
    31261 cctgatcgat tttttccagc aacatgatcg tattcagatc ctcggccatt aactgaaaat
    31321 tcaacataga tgcttcgttt gtcgaacgac catgtcctcg gctatctact agatacacgg
    31381 tatagtagcg ttcgagtaca gggacctgtt ctgaaaaaaa gcggccgctg ccgtcattgc
    31441 catgcagtaa aaagagaggg aagccttgac cgctcttttc atagtaaatt tcgctcccat
    31501 ctggcatttt tgcatatttc ttttcttttt tcacataatc acctactgtg taaagtataa
    31561 cgattatatc agtcattggg caattgtttt tactgaaaaa caacgatcat tttcgtaaga
    31621 tgtcaaaaaa tacaggaaaa ttcatttttt cttaaggcgt acacagaaat caaggaagaa
    31681 atagccaaga agataaagaa atagtaagat aaaaaaagat gtcaaaataa ctaggtgatg
    31741 aaatgaagcg aaaacgatta tctattatcc gtattctttt ttacatgatc attctgacgg
    31801 ttattggtgc ggtgttgttt ttatgaggaa gaacttatcg ttcggtaaaa cgagtggaaa
    31861 gctatcaaat agaaataaca acagctgcaa aaaattatca tatggaaaac tacgagaatt
    31921 tgatcaaggc gataatattg accgaatcaa aaggaaaagg gacagatctc atgcagagct
    31981 cggaaagtct gcatggagaa gctgagatca ttgataatcc agctgacagt attgatcaag
    32041 gtgtcaaata tttggcggaa atgatagtag aagcaaagaa acaaggatgc gatttatgga
    32101 cagctgtcca agcatataat tttgggaaag attatattgc ctatgtaaaa aatcatggcg
    32161 gagaaaacac agtagaatta gcagaagcgt attctaaaga tgtgctgagc ccacttttag
    32221 gaaatgagga agggaaacaa taccgatatt ggcggatcca gtccttgctt tacaatggcg
    32281 gctatctcta tcataatgga ggtaacatgt tttatcctga tattgtcaaa atgaatgaaa
    32341 aaataataga gacctatgaa aaagtcttta agtaaaatag caggaaatgt tcaatcatga
    32401 ataaaattaa atgaaagaag gagtgcgcaa atagtggaaa aaaggcaaaa aatggaaaat
    32461 caagaagtgg ggtacacaac caaagactgg atgttacggt ttgtgaaggg aatgtttatc
    32521 ggttcaggat ttatcttgcc aggagtcagc ggtggtgcat tagcagctgt ctttggcatg
    32581 tatgagcggc tgatttcttt tttagcccac cttacaaaaa atttcaaaga aaatgttttg
    32641 ttttttctgc ctgttggtct aggcggagtg acaggcatct ttctactttc ttttttagtc
    32701 agttttttat taggtgcgta tgaaacaacg atattatggt tttttgtcgg atgtatcgct
    32761 ggaactgttc ctgcgttatg gaaagaagca gggaaaaaag gaagagatac ttctgatgtg
    32821 atcatcatgg ttgttacttt tgttctggct tatttgtttt tattatacgg cgctcaatta
    32881 tttgacgggc aagtcgatca gaattttgga acatggctga ttgccggcgg attgattggt
    32941 ttgggtatga tcgtcccagg attgagccct tctaattttt tggtgtatat gggattgtat
    33001 aaagcgatgg ctgacggatt taaagaagta cgacttgaag tgattgtgcc gatcggaatt
    33061 ggtgggattc tttgtgttct tggattgtca aaaatcatgg attacatttt ctcaaaggca
    33121 tatagcaagc tattccattt cattttaggt gtagtttttg cttcaacgat tatgatcatt
    33181 cctaccgatt acgcgggatt gggagttgct ggggtactag cttgtcctgt tctttttata
    33241 gccggtacag cactaggttg gtggatgagc cgtttggagg aacaatataa gtaaagatag
    33301 attgataata aaaacagcac acgggtgatt caaacaaaaa ggttggcatc ttttttgtaa
    33361 aatcattcgt gtgtttttct ataaatttta taaaaacaag ttgtttttaa tcttggaaca
    33421 cgctagactt aaacacgtga ttatttttga aagttggcgg aaaatggaga aaaagaaaat
    33481 gaatggactt acacagcaag aggtagttca gaaaatggct tctggccagc aaaatgacta
    33541 ccaggaagat gcatcaaaaa gtacaaaaca aatattcagc gataatatat tgacgttatt
    33601 caattttctg aactttggta ttgggatttg tctgttattt gtaggtgcgt attccaacat
    33661 ggcgtattta gcaattattg tcgtcaatat cgttattgga atttatcaag aaatacatgc
    33721 aagaaatctt gtacggaaat tatcgattgt ttcccaatca gaagtactag tgatccggga
    33781 cggtaaagaa caatcgattt ctactaaaga gctggtatta ggagatttgg taaaaatcgg
    33841 agcaggagaa cagataccag ccgatttaca ggttatatct ggacgggcag aagcaaatga
    33901 agctcttttg acaggcgaat ctgatttgat tgtcaaagaa actggagctg aattgctttc
    33961 tggaagcttt ttgacaagcg gttctgtcat ggctgaagtt atccgagtag gtgcagataa
    34021 ttatgctgtc cgcttgacta gcgaggcaaa gactcacaaa gctattcgtt ctgaacttgt
    34081 agattcgatt cgcaaagtat ccaaattcac tagtttcgtg attattcctt tggggatcat
    34141 actatttttg gaagcactgt tcatccgcga tgcttctatc aaaatttctg ttattgcatc
    34201 tgcagcagct ttgttaggca tgcttccaaa gggtttggta ttgctaataa gtattgcatt
    34261 aacgacaggg gtaaccaaac tggcaaaaaa acgaatcctt gttcaagaca tgtattcaat
    34321 tgaaacgctg gcccatgtcg atacattatg cttggataaa acagggacca ttactgaagg
    34381 gaaaatgagt atccagcggg tagaagcact acatccgctg tacgagaaag ccatcccaga
    34441 aattatgggg acgtatctgg cagaaagcag tgataacaac atcactatgc gggctatgag
    34501 agattatttt gagctttcta atcggtatga tgtgacaaac aaagtcgcat tttcttctga
    34561 tcgcaaatgg ggcgcgatgg aatttccaga actgggagtc gtgtacgtag gagcgcctga
    34621 acgtttggtg gaagaagatc ggcttccgga cagtctaaaa acagcccaag cgaatggcta
    34681 tcgcgtactt atgttgggga tcgctccaaa tcagcaattg aacgaagaaa aaccagcatt
    34741 tgttgagccg gttgctctgt ttgaaatcga tgatccaatc cgaaaaaacg ctcaagaaac
    34801 actagcttat cttcatgagg aaggtgtgga tctgaaagtg atttctggag acaatccttt
    34861 tactgtctcc aatatcgcta gacgtgcagg attaccgaat tatgatgcgt atgtcgatct
    34921 ttctcaaatt actgaagaaa tggaagtgcg agaagctgct catcgctata cggtttttgg
    34981 acgagtgagt ccgcagcaaa agaaattgct ggtaaatgaa ttgaaagaaa gcggcagaac
    35041 ggttgcaatg acaggcgacg gtgtgaatga tgttttggcg ttaagagaag cagattgcag
    35101 cattgctatg gcagaaggtg atggagcaac acgtcagatt gcgaatctgg tattgttgga
    35161 ctctgatttt actacattgc cagaagtcct gtttgaagga cgccgagtgg tcaacaatgt
    35221 gacgaaagtc tcaggcatct tttttatcaa aacgatttat tcatttattt tatcgattat
    35281 atgtgccgtt acagcaattg gatttccgtt tatccctatc caaatcacgc tgattgattt
    35341 agcgattgaa gggtatcctt ccttcttttt atcttttgaa caagataaaa gaaaaatcac
    35401 ttaccgttat ttgcctacag cacttattaa tgctttacca aatgccttgc ttgtagtagt
    35461 gaatatcatt gcggtgtatc tacttggaaa aacattcgca tggggaaatg ctgaaactac
    35521 tactttgatg tattacttgc tgattgggat cagttgcatg gcagttgtaa aagcttgtta
    35581 tcccttcaac ccattgcgca tcttcctagc agtaacgacg atcgtaggga tatatgtagc
    35641 tgcaatgctg ttccatggaa ttttggaagt aaacttaggg ttgggagaga gcgtaggata
    35701 cttctttgta ttcatgctcg taaatattgt tcttcgagta ttgtactgga aggctgatat
    35761 tcaaaatcag ttactgaaaa gagtagcaaa ttgatgctta atgagataga aatgtgttat
    35821 acttgaaaaa gcaatgaaat atgatacaat caaacatgta taattgtgtc ctttaaaatc
    35881 gcactgattt cagttagtgc gattttttac cggttattct cctgaaatat cttctgttaa
    35941 acccaaaaga tatcaataga gcagggggtg aaaaaatggc tcaacggatt cctcaagagg
    36001 ttatcgaaac agtacgcagt caaacgaata tcgttgaggt gattggacaa tatgtccagt
    36061 tgaaaaagtc tggtaaaaat tacttggggc tgtgtccttt tcatgaagaa cgtacaccgt
    36121 ctttttctgt tgcagaagac aagcagattt ttcattgctt tggttgtggt aaaggcggaa
    36181 acgtgtttac ttttcttcaa gaactagaag gtctaagttt tccagaagca gtggtaaaag
    36241 tggcagactt cgaacagata ccgttagaag atcaatggcg tcagcgtact atagctgtcc
    36301 aaaatcctga atctgctacg gggaaactga ttgctgctca tgaaaaagca gcggaaatct
    36361 atcatcacat gctattgcat acaaaagctg gacagccagc tttagaatat ttgcaaagtc
    36421 gtgggttgtc tttagaatta attgaagaat tcaacatagg ttttgcacct aatgagcgtt
    36481 cttttcttca gcaagtattc aagaatgaat caatttcaaa tgaattgtta gaacgctctg
    36541 gattgtttgt cacgcatgat gatggccgta tgtctgatcg tttttatcaa agagtgatgt
    36601 ttccacttcg taattctcaa ggccagacga tcggtttttc aggacgctgg cttgcacctg
    36661 aaaaagggca ggaaaaagat cagcccaaat acttgaatag tccagaaaca gaactgttca
    36721 ataaaagaca agttttattt aatcttgata aagcaagaag cgatatccgg aaaaacggag
    36781 aaattttgtt gttcgaaggg tttatggatg tgattgctgc atggcaggct ggtatcaaaa
    36841 ctggattagc ttctatgggg acaagtctaa cagctcaaca gatccaacaa atggaaaagc
    36901 tgacgaaaga attggtcttt tgctatgacg gagacaacgc aggttttgaa gcaaccaatc
    36961 gagggattga attgcttcgg caaaacagtc gattagcact ttctgtcgta gtcgttccag
    37021 aaaagcttga tcctgatgaa tatctccgta agtatggaga agcatctttc caagaattag
    37081 tggctcatgg gcgcgaaaca gtctttactt ttaaatcacg ttatttaaaa caagggaaaa
    37141 atttagataa tgaaaaagac aagatcgaat acctcgaaga attactagtt gaacttagcc
    37201 gagttgtttc accaatcgaa caagatatgt atctatctca actgtcaaca gagtttcaga
    37261 tcggcagaga gacgatacaa aaacaactgc gcgatcttcg aaggacaaat cagcaaaatc
    37321 gtcaagaacc tcaggaaagt caacacactc aggttacgag acaagaaact gcacggaaaa
    37381 agagaccttt gacgcaagta gaaaaggcag agcagattct attatatcgt gcatttaaag
    37441 aagtttctgt ccgtaatatt ttaaaagaac gagaatttca gtttattcat gatgcatatg
    37501 cagaagttta ttttttattc gatgcatatg tctcacaaca ttatgaattc aaccttgcag
    37561 agtttttaga ctttttgcaa gatgaaaatt taaggcggtt ggtggtggaa atcgaatatt
    37621 taccggtggc agaagaaagt tcgccacgag aaatccaaga cttgctagat gtgatcagca
    37681 aatctggctt agctgatgaa ataacattaa aaaaacaaat gcagcaagaa gccagacgaa
    37741 ctggaaacaa acagcttgag cttgaattga cgattgaaat catcaattta acgaaacagt
    37801 taaaacaagc caaatagcta ctcaaggggg gccttctttt atggcaaatg gaacagataa
    37861 aaaaacgtat gaagcagcag tagcagcttt catcaaagaa aacaaaccca aacgacaagt
    37921 tgtatatgat gatttatcca atcagcttgc tacaccattc actttgaatg cagatgaaat
    37981 ggacaaattg atccaaaaga ttgaagacgc aggtatcagt gtggtggatg aaaatggtga
    38041 tccatcaatt cacagcttga agagtgctga gaaaaaagct gaacaagcaa aaacagaaga
    38101 tctttctgcg ccaaccggtg taaaaatcaa tgacccggtt cgtatgtatc tgaaagaaat
    38161 tggccgtgtc tcccttttaa ctgcggaaga agaagtagcg ttagcattga aaatcgaaga
    38221 aggcgaccaa gaagcgaaac agcgtctggc agaagcaaac cttcgtttag tagtaagtat
    38281 cgctaaacgt tatgtaggac gaggcatgca gttccttgac ttgatccaag aaggaaacat
    38341 gggactgatg aaggcagttg aaaaatttga ctaccgcaaa ggatttaagt tttcaaccta
    38401 tgctacatgg tggattcgtc aagccatcac tcgagcaatc gctgaccaag cacgtacgat
    38461 ccgtattcca gttcatatgg ttgaaacaat taataaattg atacgtatcc aacgtcaatt
    38521 gctgcaagac cttggaagag aacctacgcc agaagaaatc ggtgcggaaa tggatcttcc
    38581 aacagaaaaa gtccgagaaa tcttgaaaat cgcgcaagaa cctgtttccc ttgaaacgcc
    38641 aatcggtgaa gaagatgact ctcacttagg tgatttcata gaagaccagg aagcaacaag
    38701 tccagcagaa cacgcagctt atgagttact aaaagaacaa ttggaagatg tactagatac
    38761 attgactgat cgggaagaga atgtccttcg cttacgtttt ggtttagatg atggccggac
    38821 gagaacattg gaagaagtag ggaaagtatt tggtgttact cgggaacgta ttcgtcagat
    38881 cgaggctaaa gcattaagaa aattgcgcca tccttctcgt tcaaaacaat taaaagattt
    38941 cttagaataa gcgtggacta ttgaccagaa gagaaatcag taaaactgtt tggtttattt
    39001 taaaagaaaa aaagcttgag actacgcagt ctcaagcttt tttttctata ggaaggaaat
    39061 tcattcatta tttttaagta aatcctaaaa ataagctatt ggcgtgacgt atagaatatg
    39121 atagattaaa tggtagcgta aacctagtaa aggagccgat cgctaagtga tgaaaaaatg
    39181 tccaaattgc ggatcgaaaa aaatggagca gaatactatc tgtccagact gcggtcatca
    39241 aataactgca gaagatcagc aaataaaaga atcaattgaa gaaacaaata cagatgcagc
    39301 tatgcaggat aaatcaactg aagatgcagt ctttcctgat acagaattaa acgatccaat
    39361 cgaatggtcg gaattgaaag atttacctct agaatctgta atggaattat tcgaaaaagc
    39421 agaaccagaa gacgaagaac cacctgctca cgatcaagta actaatatag agaaaaatga
    39481 acagaagaaa gcaactgttc atgagacttc ggaagaatca ggaaagaatc aagaagaaac
    39541 gcttgaatca aaacaaaaaa gaagagtagc tgaactgaaa gaaatcgtcg ataatgagga
    39601 agaaaattcg atactatccg cttatatcaa agcacatcgt gaagatacaa aagaagagca
    39661 cgcgaaagag ctgctcaaaa tgatcagtga aaaaattgca caggaaaaca aagtagagcc
    39721 agaaaaggaa caagaaactg aaaaagactc tgatagagaa aacgccacag gtaaagaaac
    39781 agtaaaaata aaagacgtaa aaacggatat cacagaaaaa actgaagtat ttactgaaaa
    39841 acaattagaa aaggaaaaaa cgaataaact gccggaagca gagaaaaaag aaatactcga
    39901 aaacacagac aaaaagtcaa cagagcccga tgaaataaat agtgaatccg atgctgaaaa
    39961 tcaatctgta agcaaagagg gtactgatct tgaagcaaaa atagaaaaag aagagaacca
    40021 gcctaagctg tttgaagcag aagcgaaatc aataacaatc gtgccagata ctgaaaaaac
    40081 acatcaagaa tcaaacttag aaaaaacaga tccagataaa gcgcaaaaga aaaaatcaaa
    40141 aaaagtacct tatctcgttt tagcagcagt acttctactc ggtggaggaa gctgggctta
    40201 ttatgaccat catcaaaaag tagaagccga agtagcagca gaagcaaaaa gacagcaaca
    40261 aatggaagaa cttcatgaga aacttgctgc cttttataca gatgatcacc atcaatttat
    40321 tcgtgcagat atgattcatc aagatttatc aaaactaaaa aatgatttat ccagtcttaa
    40381 gaatgaaaaa ggatattcag agttagaaac aacttaccaa gatatccaat ctaagatccg
    40441 agatatccaa aaagtgaatg agtggttcat agcacctgcc atcgtcgatg atcatctagc
    40501 agatgacatc aagttgaaag cagataaaga gatccaagca atcgaaacgg ataacacaga
    40561 ttttggaaaa ttgattcaac aagcacaaac agaagctaaa aatcaatatg ctgaattgca
    40621 aacagctaaa gaaaaaacag ctatagtctt taaagacgga aaagtagtgg attcagcaac
    40681 acgcgaccaa tacaagacgg caaaagaagc agtagaaaaa gtgaaaaata cagatctatc
    40741 tgctcagttg aatgaacaat tgaaacaagt agataagatg ctcactgata aagagaaaaa
    40801 agaagaagag gaaaagaaaa aagcagaaga agcgaaaaaa gcagctgaag aacaagcaaa
    40861 acaagccgct caagcagcag ctgcagctca agccgctcaa caagctgcgg tcgcacaagc
    40921 agcacagcaa gaagcggcat cctcgacccc ttcctcttca aactcagcga atcagccaat
    40981 caaatctgcc agagcaagtg atattgccga tgcatctaat ccagcatgga cgtgggcacc
    41041 aggtgtccaa agcaaagtga ttgctacatg tatccaacgt ggatatatcg ttgaaggagg
    41101 ttacagatta gaaaaagcca gaatcgaaaa tggggaaggc tattataatc tatatgccac
    41161 ttcaacaaaa tctgcattga tgaaaggcat tggagaaagt gctttgccat tttacatcgt
    41221 aaccatcaac tgtaaaactg gatggttcgg aggaaatggg agcaattaat tttaggcaaa
    41281 tgaaagaggc tgtgagcctg ccgtttaaca ccgtttattc gaaaaagggg agtatgacac
    41341 aactgttgtc atactccttt tttcaccttt ccaaaccaag gctcagctat tcaagtagat
    41401 aacattatgt tatgatagca aagaaatgta ttaagaaaac ctttcactat agagggagaa
    41461 aaaaatgaac gatttattag caactatatt tacaggtatt attattgatg aaaatgaaaa
    41521 aaactacttt gtccaaaaaa acggacaaac ctttggctta agcaaatcag aaggtgaaca
    41581 caaaatcggt gaagcagttg aaggattcgg ttaccaaaat caaaaacatg aaaatcggat
    41641 cactacacaa attcctaaaa gccgtatcgg tcattacgct tttggaatcg ttactgctac
    41701 acgaaaagat ttaggtgcgt ttgtcgatat cggtcttcca gataaagact ttgtcgtatc
    41761 tcttgatgaa ttgccgacaa tgacagagct atggcctaaa aaaggggatc gcttgatgat
    41821 ttcccttaga gttgatgcaa aagaccgtat ttggggcagt ttagcagatg aaaaaatatt
    41881 caaatcttta agcaaatatg gaacagaaga aatgaaaaac aaagatgtga taggaacagc
    41941 ataccgcttg aaattaacag gtacgtacgt tttaacggaa gatttctatc ttgggtttat
    42001 ccatccttct gaacgatata atgaacctcg tctaggcgag cagataaaag gtcgagtgat
    42061 tggtgtccga ccagacggtg tactgaatct ttcattgaag ccaagagcat atgaagctat
    42121 atcagatgat gcacaaatga ttttaaccat tttagaacgt tctgcagatc agcaaatcaa
    42181 ctttacagat aaatcggatc cagaagaaat catgaaagct tttggtatca gcaaaggagc
    42241 atttaagcgc gcattaggta atcttttgaa acaaggattg attacacaag aaaacggtgt
    42301 gacaaaacta gtcaaaaaat ctaattgaga atcccttgca tgtttttctt aactagctta
    42361 taataatttt aattaacata gtgttatatc tttttttatt tgtaattatt ataaattgtt
    42421 ggggttgagt aaatggtcat gaatgctatt tcggcgatga aaaaaacaaa acagcagcta
    42481 catgaagcgg ggtttaagct gacaccgcaa agagaagcta ctctgcttgt gcttttggaa
    42541 aatgagaaag agcatttatc tgcagaagaa atcttctttt tagtgaaaaa aaagagtccg
    42601 gaaattggac ttgctactgt ttatcgaacc cttgaaatct tgacagaatt gaaaattgtc
    42661 gataaagtaa gttttaatga tggattagcc cgttatgatt tgagaaaaga aggcgccaaa
    42721 catttccatc atcatttact atgcttgaac tgcggcacga tcgaggaagt agaagaggat
    42781 cttttacttg aagtggagca agtagtagaa gaacgttatc attttttagt aaaagatcat
    42841 cggctaacgt tccatggaat ctgtcaggaa tgctatgaaa aagaaa
//
LOCUS       DARPZF010000019        41153 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.019, whole genome shotgun sequence.
ACCESSION   DARPZF010000019 DARPZF010000000
VERSION     DARPZF010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41153
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.019"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            238..480
                     /locus_tag="SLE65_001344"
     CDS             238..480
                     /locus_tag="SLE65_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HEI8448650.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            477..947
                     /locus_tag="SLE65_001345"
     CDS             477..947
                     /locus_tag="SLE65_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HEI8448651.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            1075..2289
                     /locus_tag="SLE65_001346"
     CDS             1075..2289
                     /locus_tag="SLE65_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEI8448652.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQP
                     LNDELREIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDY
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKEKYKAGECMSYFRMQKDYSGTEKCGSDLPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTAVPQENDGIF"
     gene            3278..3487
                     /locus_tag="SLE65_001347"
     CDS             3278..3487
                     /locus_tag="SLE65_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HEI8448653.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            3599..5212
                     /locus_tag="SLE65_001348"
     CDS             3599..5212
                     /locus_tag="SLE65_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8448654.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            5247..6458
                     /locus_tag="SLE65_001349"
                     /pseudo
     CDS             5247..6458
                     /locus_tag="SLE65_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            6481..7407
                     /gene="glsA"
                     /locus_tag="SLE65_001350"
     CDS             6481..7407
                     /gene="glsA"
                     /locus_tag="SLE65_001350"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HEI8448655.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            7615..9075
                     /locus_tag="SLE65_001351"
     CDS             7615..9075
                     /locus_tag="SLE65_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448656.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            9296..11059
                     /locus_tag="SLE65_001352"
     CDS             9296..11059
                     /locus_tag="SLE65_001352"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HEI8448657.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            11143..11601
                     /locus_tag="SLE65_001353"
     CDS             11143..11601
                     /locus_tag="SLE65_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEI8448658.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            11710..12393
                     /locus_tag="SLE65_001354"
     CDS             11710..12393
                     /locus_tag="SLE65_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEI8448659.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            12540..13154
                     /locus_tag="SLE65_001355"
     CDS             12540..13154
                     /locus_tag="SLE65_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HEI8448660.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            13170..13376
                     /locus_tag="SLE65_001356"
     CDS             13170..13376
                     /locus_tag="SLE65_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448661.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            13917..15047
                     /locus_tag="SLE65_001357"
     CDS             13917..15047
                     /locus_tag="SLE65_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEI8448662.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            15139..15894
                     /locus_tag="SLE65_001358"
     CDS             15139..15894
                     /locus_tag="SLE65_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEI8448663.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            15952..17991
                     /locus_tag="SLE65_001359"
     CDS             15952..17991
                     /locus_tag="SLE65_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HEI8448664.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQATRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(18100..19251)
                     /locus_tag="SLE65_001360"
     CDS             complement(18100..19251)
                     /locus_tag="SLE65_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEI8448665.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(19405..19935)
                     /locus_tag="SLE65_001361"
     CDS             complement(19405..19935)
                     /locus_tag="SLE65_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HEI8448666.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(20034..20384)
                     /locus_tag="SLE65_001362"
     CDS             complement(20034..20384)
                     /locus_tag="SLE65_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEI8448667.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(20541..22070)
                     /gene="ahpF"
                     /locus_tag="SLE65_001363"
     CDS             complement(20541..22070)
                     /gene="ahpF"
                     /locus_tag="SLE65_001363"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEI8448668.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(22080..22643)
                     /gene="ahpC"
                     /locus_tag="SLE65_001364"
     CDS             complement(22080..22643)
                     /gene="ahpC"
                     /locus_tag="SLE65_001364"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEI8448669.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(22787..23449)
                     /locus_tag="SLE65_001365"
     CDS             complement(22787..23449)
                     /locus_tag="SLE65_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8448670.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            23633..25279
                     /locus_tag="SLE65_001366"
     CDS             23633..25279
                     /locus_tag="SLE65_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HEI8448671.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            25270..26352
                     /gene="uxuA"
                     /locus_tag="SLE65_001367"
     CDS             25270..26352
                     /gene="uxuA"
                     /locus_tag="SLE65_001367"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEI8448672.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(26460..28013)
                     /locus_tag="SLE65_001368"
                     /pseudo
     CDS             complement(26460..28013)
                     /locus_tag="SLE65_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            28161..29302
                     /locus_tag="SLE65_001369"
                     /pseudo
     CDS             28161..29302
                     /locus_tag="SLE65_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(29428..30507)
                     /locus_tag="SLE65_001370"
     CDS             complement(29428..30507)
                     /locus_tag="SLE65_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEI8448673.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(30610..31050)
                     /locus_tag="SLE65_001371"
     CDS             complement(30610..31050)
                     /locus_tag="SLE65_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEI8448674.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(31107..31517)
                     /locus_tag="SLE65_001372"
     CDS             complement(31107..31517)
                     /locus_tag="SLE65_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HEI8448675.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAHGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(31697..32131)
                     /locus_tag="SLE65_001373"
     CDS             complement(31697..32131)
                     /locus_tag="SLE65_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEI8448676.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(32231..33079)
                     /locus_tag="SLE65_001374"
     CDS             complement(32231..33079)
                     /locus_tag="SLE65_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEI8448677.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            33468..35234
                     /locus_tag="SLE65_001375"
     CDS             33468..35234
                     /locus_tag="SLE65_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEI8448678.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            35336..36595
                     /locus_tag="SLE65_001376"
     CDS             35336..36595
                     /locus_tag="SLE65_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEI8448679.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            36742..38043
                     /locus_tag="SLE65_001377"
     CDS             36742..38043
                     /locus_tag="SLE65_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8448680.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSQQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            38046..38897
                     /locus_tag="SLE65_001378"
     CDS             38046..38897
                     /locus_tag="SLE65_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8448681.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            38910..39725
                     /locus_tag="SLE65_001379"
     CDS             38910..39725
                     /locus_tag="SLE65_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HEI8448682.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            39876..41042
                     /locus_tag="SLE65_001380"
     CDS             39876..41042
                     /locus_tag="SLE65_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEI8448683.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
BASE COUNT        13972 a         7121 c         7990 g        12070 t
ORIGIN      
        1 aaataagaaa ttgattgtcg ttttcttttg cagaaattta agtgcaggca attatggtag
       61 ttgtcgtaat tgctgtcagc tcagtgttta tcactgatgg tgtgaaagat ttacggttgg
      121 agatgttcaa taagattatt ggtgcttaat tatttttatt gtagtgctga tatgagaatg
      181 ttataattgg ggtataaaac atacaaataa atttgctgaa aaatgaggta tcaaaatatg
      241 gaaaatgaat tactggaaaa cttaggaaga cttcacacaa ctgaacttgg cgttattaga
      301 attaaaaaga acttatcttt gaatgtagaa aatgtaattg aatggtgcaa agaaaaaatt
      361 agcctttcta atgcggaaat cacaagaaaa ggaaaaaact ggtatataac gattgataat
      421 tgtattataa cggtaaatgc gtacagttat accgttatca ctgctcacaa ggtaaaatga
      481 taaatttttc tataaaggaa ttaaacgcat ttgcagttat tgggcaggaa gtagaactga
      541 ctaattatca aaaaaagaat attcagatta gtacacagtt ttggagaaag tttaacagta
      601 gtttgaaaaa agcgtatctt tcacaatcag gaaattgggt aaaatatgct tttatggaaa
      661 gaagaaatgg aaaactttat tatttctgtt ctattcccca aagaaccatt accccagagg
      721 gctttctgta taaagaaata ccgtcttata aatatttggt tgtggagcat attggtgcta
      781 tggataaaat atatgaaact tatggcaaga tttatgaaga aattattcct agtacatcgt
      841 atattcctat aaaagatatt atcctacact ttgaaaaata cgattatcgt tttcattgga
      901 atagtgataa ttcagttatt gaaatttgga tacctattca agattagaag caattttata
      961 tccatacaca caaagcagtt agtcttagga ttgactgctt tttctataca gatttttaat
     1021 gacaggcaat tatcaattat ggtagttgcc ttttttgatt ggaggaattg aagaatgaat
     1081 gataaaaact ttattgaaga actaagacaa aagcgtgagg aatacggagt aacacaaaca
     1141 aggcttgctg ttgcctgtgg tatcagccgt gaatattaca accgcattga aaaaggaaaa
     1201 cagccattga atgacgaatt aagagaaatc atagaaaaac agattgagcg tttcaatccg
     1261 caagaaccac tattcttatt gattgattac tttcgtgtcc gctttcctac tacggacgca
     1321 ttggcgatta tccgtgatgt attacaactg aaatctaatt acatgcttta tgaagattat
     1381 ggaaaatacg gatatgaaag caaatatgta cttggcgaca tcaatatcat gtgttccatg
     1441 caggagcatt taggtgtttt attggaactg aaaggcaaag gctgtcggca aatggaatgt
     1501 tatctgctgg cacaggaacg ctcatggtat gacttcatgc tggattgtat gacggctggt
     1561 ggtgtgatga aacggcttga tttggctatc aatgataaag caggaatatt ggatattcca
     1621 aagttaaagg aaaaatacaa ggctggcgaa tgtatgtcct acttccgtat gcagaaagat
     1681 tacagcggta cagaaaaatg cggtagcgat ttaccaaaga atacaggaga aaccttatat
     1741 ctcggttcaa caagtagcga attatatatg tgtgcttatc agaaaaatta tgagcagtat
     1801 gtcaagaatg gcacagaaat tgaagatacg gagattaaga accgttttga aatacgcatg
     1861 aagaacgaac gagcctatta tgcggttgta gatttactga cctatcggga cgctgaacgc
     1921 accgcttttt ctatcatcaa tcattatgtc cgctttgttg acagagagga cgacaagcca
     1981 aaaagtcaat ggataacaaa tgatgattgg gcatggtttg taggggaaaa cagagagccg
     2041 atacgcttaa ccacaaagcc agagccttac actttacaaa aagcgttgca ttggctacaa
     2101 agacaagtcg caccaaccat aaaaatggta caggcattag acagagaaaa tcgtacaacg
     2161 atactgaaag atatgattga gcaggcagaa ctaaaagaca agcataaaca tttattacaa
     2221 ttagagaaat caaccataga agaacgtata gataccgctg ttccacaaga gaatgacggt
     2281 attttttaat gtaattgaaa aatttcagat ttagtcagca aagagctgtt ttcattccct
     2341 atgtgaagtg aaagaagaaa aataaatttt ttattaaatc tgcaacaaaa tggctacttg
     2401 cgtacagata tggtgcgaga aaaggaaatc taaacttttt ttgaaaatag gtcattaaat
     2461 cggggcttgc tgtccctata tgaagtgaaa gaagaaaaaa gttttgaaaa aatgacggaa
     2521 attcgtgatt agtggacagt cttctgtgaa aagaggaaaa acatcatcat tttgtattca
     2581 aacaggcatt agcagttgag tgttgatgtg aaaagatgaa aatactttgt tctcaactta
     2641 acaatttaag gtttccgttc cctatatggt gcaaagaaaa tatttcattc tattgttggc
     2701 agtaacggta tggtttgggt agttagggtg tgaaaaggaa aatattcttt tttcatcatc
     2761 aacttagcaa aatgacattt tctatcccta tatggtgcat gaaaagaagt taaaattttt
     2821 ccatttaaac ttagcaaatg gacgtttgct gtacagatag tagtgaaaaa ggagaaaatc
     2881 aaccgttgat tgccaaaatg aaccgttcca tttgtactaa taatggaaaa agttttggat
     2941 tttggttacg tttctcctct tttccaacgc gatatatagg aaagacgatt tttttctttc
     3001 aatcgttctt tgacaactga ataaagctat tcaatacgtt tgacagacag ctagccgttg
     3061 aaacaaatac gccacgacct ttcccctgca agagcgagcg aaaacctatt tgtgttcttg
     3121 taaaagattt gtcctctttt atcgccatga cctgtactgt cagataatga tactcccgta
     3181 cagccacagc ttgagcatta agagcgtcgc acgcaatggg tacggctaca taagaactat
     3241 gcagaggtgg aactcctgtg ggctatgaca aaagccgttg aattgcttag aaagatttta
     3301 cagaaagggg gtatgtgtta ttgataatgc tgtaaaaaca attcaaaaga aaaatggcaa
     3361 gtgtggcatt ggcaacagag gaaagacaaa gattgtagta aaagagcatt tttccgaaaa
     3421 gggcaaaaca atggaagaac ttctaactga tgtcatgctg gaaaaagcaa agcagacaat
     3481 cgcataaaat cggtgcagtt gtaagaaata gattgaatga caaaaagtac ccgtgttata
     3541 ctttacttgc aagcaggtat tgtaaacacg ggttagttat aaaggaggat aactgacaat
     3601 gaaacaacag atttacaata ctgcacttta tcttaggtta agccgagatg atgaattaca
     3661 gggcgaaagt tccagcatta ccacacagag aagtatgttg cgtttatatg caaaagaaca
     3721 tcatttgaat gtcattgatg aatatattga tgacggctgg tcgggaacaa attttgacag
     3781 accgagtttt caaagaatga ttgaggatat agaggcagga aaaatcaact gtgttgtaac
     3841 gaaagacctt tcccgtcttg gcagaaatta tattatgaca ggacaatata cagaattgta
     3901 tttccctagt cataatgtcc gctacatagc gattgatgac ggtgtagaca gcgaaaaagg
     3961 cgaaagtgag attgcaccat ttaagaacat catcaatgaa tgggtggcaa gagatacaag
     4021 ccgtaaagtc aaatcagcat ttaagacaaa gtttgcggag ggggctcatt acggtgctta
     4081 tgctccgtta ggatataaga aacaccctga catcaaagga aaactgttgg ttgatgatga
     4141 aacaaaatgg attattgaaa aaatcttttc cctagcctat caaggttacg gaagtgcaaa
     4201 aatcacaaag cagttaagag cagaaaaagt tccgacagcg tcatggctaa attttacaag
     4261 atacggtact tttgcacata tctttgaggg aaaacccgaa agtaagcgtt atgagtggac
     4321 gattgctcat gtcaaggcga tattgaaaag tgaggtttat atcggaaaca gtgttcacaa
     4381 tatgcagtct acggtatcgt tcaagagcaa aaagaaagtg cgtaagcccg aaagtgaatg
     4441 gtttcgagta gaaaacactc acgagccgat tattgacaag gaagtgttct atcgtgtgca
     4501 ggagcagata aaatcaagac gcagacagac aaaggaaaag gcaacgccga tttttgcagg
     4561 gcttgtcaag tgtgcggatt gtggttggtc tatgagattt ggaacgaata agacaaataa
     4621 aacgccttac agttattatg cttgcagtta ctacgggcag tttggcaaag gtaattgttc
     4681 tatgcactac attcgttatg atgtgctgta tcaagccgta ttggaacgct tgcagtattg
     4741 ggctaaggca gtacagcagg acgaagaaaa ggtattgaac aagatacaga aagctggcaa
     4801 tgcagagaga atacgggaaa agaagaaaaa ggcaagtaca ttgaagaaag ccgagaacag
     4861 acaaaatgag attgaccgtt tatttgcgaa aatgtatgaa gatagagcct gtgagaagat
     4921 aacagagcga aattttgtga tgttgtccag caagtaccaa aaagaacaga tagaactgga
     4981 acagcagata acaagcctaa gagaagaact aagtaaaatg gaacaggata tgataggtgc
     5041 tgaaaagtgg attgagttaa tcaaggaata ttccgtacca aaggaactga cagcaccatt
     5101 attaaatgcc atgatagaaa aaatcctcat acatgaagca acaacgaatg aggataacga
     5161 aagaatacag gaaattgaga tatattaccg atttattgga agagttgagt aatcaacaag
     5221 agtaatattt ttaactaagg gaaaccggcg gtgtctatac ttgggtcagt cgcacattgg
     5281 gaaaacgatt cggttttgcc gcaatctttt tccaatggtt tgagataaca gttggctact
     5341 tgaccatgct gtatttctta actggtgcat tatcctatgc aacgggtatt ggtgctatac
     5401 aaaacaataa atatctgaaa ttggcaatcc tattgattat tttctgggct attttactct
     5461 cacagttaaa aggaaccaaa tacacttcat tgattgctcg gatcggtttt gtagctggta
     5521 tcttgttgcc agcattagtc ttgtttggct tagggatcca ttatgtcgct tcaggcgctc
     5581 cactacaaac gatactgtct atgaaaacat tgattcctga tttttcgaaa ttgcctacgc
     5641 tggttgtttt tgtttccttt attttagcat atatgggcgt agaaacatct gccagtcatg
     5701 caaatgaaat ggaaaaccct aaaaaggatt atccattagc aatgtttgta ttggttattc
     5761 tggcaatcat tttagatact tttggcggat tgaccgtcgc tactacagta cctcaacatg
     5821 gtttgtctct taatacaggg gtgattcaat cgttagaatt cctattaaga cacattgatc
     5881 caaatcttgc atggattgcg aaaattcttg cgattcttgt ttgtttaggt gtcatcggag
     5941 aaattgcttc ttgggtaacc tctccttcaa aagcacttca cgtagcagca gaagaaggat
     6001 tacttcctga atattttgca aaagaaaaca cacacggtgt tcctgctcat ttgatgatcg
     6061 caaatgggat cgttgcaaca atctgggcag ccgtctttac attaagcggc ggggggaata
     6121 atctttcatt tcttgcagcg atgtcattga ctgttgtaat ctacctgatg ttgtacttta
     6181 tgtttttcgc gggctatttg aagctggttt ttaaagatga cagtcttgaa agagcctatc
     6241 aggttccagg cggaaaagtt gtaaaagtaa tcgttgcttg tttaggtctt ttgacttcac
     6301 tttttgcttt ttgtatctca tttgttccac ctgctagtat cgcagctgga cagcatggga
     6361 tttatgaaac gattctgatt gtttcttatc ttatcgtctt agttattcca tttacgatct
     6421 acgcatgccg tcataaattc cagcatgcag aaaaataaaa aatgaaagct ggttattcaa
     6481 atggaagtaa aagaattaga acaattgatt ggaaaaaatt tccactatta tcaaacagga
     6541 caagtggcgg attacattcc agcattagct gaagtggatc ccaaacaatt aggtatggcg
     6601 atttatgatt tggatacaaa acaactgatt gagggaggag acgccgatgt gcgctttgcc
     6661 atcgaaagca tgtcaaaagt tcccgtattg ttattagcaa tcaaagacaa cggaatagaa
     6721 aaagtctttc aaacaatcaa cacggaacca accggttttg ccttcaattc tatcatgaat
     6781 atggaaatca atcatcgcaa acatccaatg aatccttttg ttaatgcagg agcgattgca
     6841 acaacctcgt tgattgccgg taaagatgca gatgaaaaat ttgagcgaat cttgtcattt
     6901 atgaaagaga tctgtgatga tcctaatatc acattgaatg aagaaatcta tcattctgaa
     6961 tcaagaacag gtgatatcaa tcgctctctt gcttactata tgaaaggtaa tcaaatgatc
     7021 gaaggagacg taccggagat actcgatgct tatttcagac aatgctccct caatgtcacc
     7081 gctacaggca tagcaaaatt agctgctgtg ctggcaaata aaggaattgc tccttggaat
     7141 ggcaaacaaa tcattactga agaaagtgct acaatcgtca aatcaattat gacaactgct
     7201 ggtttgtatg atgaatcagg agagttttcc gtccatgttg gtgtacctgc aaaaagcggt
     7261 gtaggcggcg ggttgatggc agctgtgcca aatcgttacg gcataggtgt cttcagcccg
     7321 gcactagatc catttggtaa cagcgcagct ggtatccaat tgttgaaaga tgtagtcaaa
     7381 gaactagacg ctgacatctt tgaataacca ttcttgaaag aggctggggt aaaagtccaa
     7441 acggctcaaa gctacctaca atgaggctga aattgtgagc ttgtttgact tttgtcccag
     7501 tttctttttt tattggtttt tgaaagggct tttctaaata aaaaggaaac aaaaatacga
     7561 tttacagata tgattaaata aaatcataag aaaaactgga ggcgtgtatc aggaatgctg
     7621 gaaaattaca tcgagcgaaa tatatttaga aaagtgtatc tgtgtgaaca attatttgaa
     7681 ttccaagaaa tagacatcga acaaacagct atttctctaa gggtgactac accaacgatc
     7741 cttcacgatc tagaaagtct agccgagtgt ctagaatatt gtataaaaga acaagtaaga
     7801 gagaagcata agtataaact cgtattcaaa catggtattg ctctttctga gctcacacag
     7861 tttctgtacg gtcaatctta ttttttaaag tttttaagtt attattttaa tggtatattc
     7921 acgagtacag aactggctga tcttgaattt atttctttga gtaaagtata tacaatcaaa
     7981 aaaatcgtat tggatttttt taaagaaaat gattatttga aaaataaaga aatcattatc
     8041 ccagaatttg actcgcggaa catcttgcta gctttagtac gttatgtcaa ttgggaaggc
     8101 tatgaaaata aaaatccgta tgtagaagaa gcttgtaacg agttgattga ttatgtagag
     8161 actcattttt ttaaaagaag atattcggaa gatgaaaagt cctttatcat acgagaaata
     8221 gagatcgcaa tcggaagaaa ggcatttccc cttggactga aagaagaaga taagaaaagc
     8281 gcagaaacga agccgttatt tcaattagtc tgtcaaggat tggaagagca aaaaggaatt
     8341 ctagacttac aagaagaaga tgtctattat attttttctt tgttcaacag tagaaattat
     8401 accaatgaga acatggagct gttaagaaaa gatttcgaag ttgtttataa aaattttgtt
     8461 ctcaatgacc tatcactgaa tgaattgatt ttacagatta ttagtatcgc tgaaatcgac
     8521 gatgcagaaa attttatttt caagcaatcc tttttacaat ttgtccgtac gttgtgggca
     8581 gatggacaag tatttttacc ggaaaggatc tatcttctat cagaaaaaga acaacttctg
     8641 tacggaaaaa ttgtagaaat attggaagag tggaaaaaga aaaatcaaat ccaactaaga
     8701 tggaatgaaa atttcattcg aaaattcgtc aaaagtcttt ctttgatcaa cagtgaacaa
     8761 gcggggagac aggaaataga aatttttgtt gtttcagaaa gttcagtcaa acaatttttt
     8821 tatcgaaccc aatttcattt gtatgcggaa gaaggcatcg ctgaaataaa tcctatttta
     8881 tttcgttcat tagaagaatt gcctgatgaa tgtctatgtg cgaaaaaaag agtggttttg
     8941 tgcgatgctg ctagctatca aaatggatta gaaactgaaa agacaaagat ctatccaatc
     9001 tcattaaaag gtgcaaacat ccatttgtat catattgctc aggaacttca cctattaaaa
     9061 aaacatattt cttgatgaga ccttaattag gagaccttct acaaagcttt ttaattgtct
     9121 gtagaaggtt tttatttgag tcctgattcg tgcgaagatc tacttatata acaagctttc
     9181 tctgaaattt ttttaaaatg ctattgactt agagtcaact ctaagtagta gaatagataa
     9241 agtgtaacaa atctattttc attaaaagaa gatagtacgg aggagagaat gtattatgag
     9301 tacagtatta catgtattgg atgcaatcaa tagccccgca gatgtcaaaa aattatctgt
     9361 tgaggaaatg aaacagttgg cagaagagat gcgccaaaaa atcttgcaaa aggacagcga
     9421 tgtaggtggg cacgttggtc cgaatctagg tgtagtagaa ttaacgattg cgtttcatta
     9481 tgtatttgat tcaccaaagg ataaaatcgt ttgggatgtt tcccatcagt cttatggtca
     9541 taagctttta actggtcgaa aaaatggttt tgaaaaagga cattaccgtg aagtgagcgg
     9601 atattccaac caacatgaaa gtaaacatga ctattttaca gtggggcaca catctacatc
     9661 tatcagctta gcaacaggtt tagctaaagc gagagatctg aagaaagaat caggaaatgt
     9721 ggtagcattt atcggtgacg gctccctaag tggtggctta gcttttgaag gattgaacaa
     9781 tggtggtgtt ttacaatcca atctaatcgt attagtaaac gataatgaga tgtctattga
     9841 tgagaatcat ggcagtttat ataaaaactt agctgagctt cgtcaaacca acggtaaaag
     9901 cagcaataac ctatttaaag caatgggatt tgattatcgt tacgtggata atggaaacga
     9961 tctggaaacg gtgatccgtt tatttgaaga agtaaaagat attgatcatc cgattgtact
    10021 tcacgtccat acggaaaaag gtcgcggtta tcagccggca atcgataata aaatgaaata
    10081 tcattggcat gtaccatttg atctgtccac cggggaggca aagcaagtaa cttctggaga
    10141 aacatttaat atgatcatca tggattattt ggataagaaa atgcaaacaa gtacagctcc
    10201 tattgccgca gtcaatgcag cgataccagg cgcctttgga ctgaaaacat tccaagaaaa
    10261 acatccagat cattattttg acgtggggat cgctgaacag cactctatca ctttcgcttc
    10321 tgctttggct tctcagggag tacgtccagt cgtcttccaa tcaagtactt tcttgcaacg
    10381 ggcatatgat caattatcac atgatttagc gatcaacgag aatccagtga ttattttagt
    10441 cggtggcgga acgatctcag ctagtgaccg aacacaccaa ggaacatttg acattcctta
    10501 cttatcaagt atcccgaaca tcaaatatct tgctccagca acaaaagagg atatgatctc
    10561 tatgctagat tgggcgttcg aacaaacagc gcagcctgta gcaatccgaa ttcctacaca
    10621 tggtgtagaa catggtacag ctatcgcaaa tgattatagt attccagcct atcaaacagt
    10681 aaataatgga ggaaaagtag caattttagc tttaggcggt tttcttgaat taggaaaaga
    10741 aacagtaaaa gcttttagaa aaaaaggaat cgaagcaacg ttgatcaatc caggaacgat
    10801 cacagaaaat gacgtagaaa cattagataa attaaaagaa acacacgaat tagtcatcac
    10861 attagaagat ggtagtttgt caggaggatt tggcgaaaat atcagtcgtt attatggtga
    10921 ttcttcaatg aacgtattaa attttggtgc agagaaagaa ttcacggata gcgttcctgt
    10981 agggcagctt tatgaacgtt atcatttaac accaaaacaa atcgttgaag atagtctgcg
    11041 tgtcttgaat attcaataat tcattatgct caccatccag ataattgttt atactagtat
    11101 ctggatggtt ttttcattat aaaaagcaaa ggggtggatg ttatgtatca gcaagtagaa
    11161 gaatatgtca aaaagttcca agaaaaatat cctagttatc aatcagaaaa attaggtttc
    11221 ttttcatttg gggatacaga aaaaatggca gacgagttga gcgaactagt tgtaaaaaag
    11281 ataaagactg gtacatcaag tggttacgat ctgtataaac aagagaatga gcctttacca
    11341 aaagttggtc aattagacgt ggtcctgaat ggaaaaaatg aaccagtttg tatcatcaaa
    11401 aatataaatg tgaccatctt gccttttagt gaagtcacga aagagcatgc ttggaaagaa
    11461 ggagaagggg atcggacatt agcttattgg cggaaagtcc atgctgagtt ttttaaacat
    11521 gcttataaag aagcgttgaa catagaattt acagaagaga agctggtcgt atacgaagaa
    11581 tttgaagtaa ttttctttta gtaagaaagg tctgctgaaa gaaatagctc attattgtct
    11641 cctgaataga aaagggttac atttttatat gaagctgtat ttttatataa cattactgga
    11701 ggagatattg tggatacact ggaacaaatc aaaggcggag tcgtcgtttc ttgtcaagct
    11761 ttggaaaacg agccgctaca cagttctttt attatgggga gaatggcttt ggctgcaaaa
    11821 gaaggcggag cagttggtat tcgagcaaat acgacagaag atatcaatga aatcaagcga
    11881 atcgttgatt taccggtaat agggattatc aaaagagatt acgatgggtc agaagtgttt
    11941 attactgcga cagaaaaaga agtggaagaa cttttggaga cgcaagcaga aatcattgca
    12001 ctggatgcaa cttctcgtaa acgtccgaca gaaaaaacaa ctgctgaact tgtccaaatg
    12061 attcacgaac acggtcggtt agctatggca gatatttcga cttttgagga agcgcttcaa
    12121 gcgcaagaag atggttttga tcttttgtct acgactttag caggctatac agaatattca
    12181 cgaaagacgc agacacctga ttttgattta ttgaatcaaa tcatagaaca agtcgatatc
    12241 ccagtaatta tggaaggaca tactgactct cctgaacaag tagagaaagc atatgaatta
    12301 ggtgcttttt cagtcgtagt tggatctatt atcacccgtc cgcaattgat cactaaaaga
    12361 tatgtcgaag ccgcaagtaa agcaaataac taaaaaacac gcacggcaca gattcttgac
    12421 aaaaaagaaa aattgataga tagtttaaag cagattctaa gaagatgaaa aaagcattac
    12481 ttttcatttt gtcttcaaga tctgcttttt aacgaatttt atagaaagaa ggcgaaacca
    12541 tgtttgaacg gagtccttca gaattgacag aacgtgaaaa ttacaagttg ctgattggtt
    12601 cagtcatccc tagaccagta gcagtagtaa cgactaaatc agcaaaagat atagtgaata
    12661 tcgcaccctt cagttacttc aatatcgtca gttcgaatcg acccatctta tccttggcga
    12721 tccagagaaa acaagatgca gtaaaagaca cagcaaagaa tattcttgag acaagagaag
    12781 ctgttatcca tatccttgat gaggacaacg tagaagaagt aaataaaaca gcagccaatc
    12841 tgcctaatga ggaaagcgaa ctgtacctga ctgacttgac tttaactgat tcagtaatca
    12901 tttcagtacc agcattgaca gaagcaaaag ttcgttttga aacatcctta tatgaacatg
    12961 tcgagatacg gaataaaaat aaagtaacag ctgatttatt tttgctagaa gtacagaaat
    13021 atcatttaaa tgaaacagtc tatgatgata agacaggaag gatcgatcca agaaaattga
    13081 atgctgtaag ccgtttggca ggaaatgatt atgcagcaat aggagaaatt ttcacgattg
    13141 cacgtcccga ataaaaagga gcactagtta tgttaaaaat aagctataaa ccatcgacag
    13201 attcaaaaga aatgaaaaaa gaatatgaaa cagtgaatga ttttctgcaa gggcagtact
    13261 tagaagttcc gccattgcaa gaccattttg tcgttactac tgttacttta gatggtaagg
    13321 aaatagaaat gccagatcaa acgattagcg gattgtttaa ttactttaac aaataaatat
    13381 ttattccgaa aagtgaaaaa acatataaaa aaacacataa aactaaaaaa ttatcaaaga
    13441 atcctggtgc aactgaaaga atttgcaacg ggattctttc aacttatttg ttattttttt
    13501 ctaaaaaata ttaaagattg ttaaatttca ctatttcatt tcaaattcca ttgcctaatc
    13561 attaggaaaa gtctatcatg aactcgtaaa tagaatatag taataacctt gttaggtgag
    13621 gctcctatac aaacataggc tgttgcccag aaacgtcgaa agtcgccaat gggtaaaaca
    13681 gaaactgttg gattaaggct ttttccaata gctaagaatg ttttctttac gttgtatagt
    13741 gctaaaactc ggacgatgag atgatgctag gtcagaattc ttgttcgaaa aggtttctga
    13801 ccttttcttt atatttttgt gactgactta tttgatgaga caaactcgct cctcacctga
    13861 caagtggatt gctgtgtgag gaggagatgc ggtgaaaaaa gatcgattgg tggattttgg
    13921 gtccttattt gactttgtcc atgatcggtc ttttagaagt atacagtgcc agttcttatc
    13981 gtttattgca agccgatgaa aatacaaaaa gtctattatt gcgtcaacta attttcatat
    14041 ttttgagttg gagcgtgatc ttcttagctc gttcagtcaa actacactat ttacttcacc
    14101 ctaaaatagc aggatacggt ttagccttat cgattttctt tttagtatta gtaagaatag
    14161 ggatattcgg tgtcactgtc aacggcgcac aacgttggat ctctctgttt ggcattcaat
    14221 tccagccttc tgaactggca aatctttttt tgatttttta tttaagctgg ttttttcgtg
    14281 acggaaatag tagcccaaaa gatctaaaaa aaccattcct gattacagta ggtataactt
    14341 ttctgatttt atttcagcca aagattgctg gagcattgat gatcctttcg attgcgtggg
    14401 tcatattttg ggcagcggcg gttccattta aaaaagggat ctatctaatc gttacttttt
    14461 ctgcattgct gattggagca gcaggcgggg tattatattt aggaaataaa ggttggcttc
    14521 cacagatgtt taatcatgct tatgaaagga tcgcgacttt aagagattct tttatcgata
    14581 gtcatggtgc gggctatcaa atgacccatt cgttttatgc actatataat ggtggcatat
    14641 ttgggcgggg attaggaaat agtatcacaa aaaaagggta tcttccagag acagaaacag
    14701 attttatttt ttcgattatt acagaagagc ttgggctaat cggtgcattg tgtgtgcttt
    14761 tcttattgtt ctcattatgc atgagaatct tttgtttaag cagtcgctgt aaaaatcagc
    14821 aagctggatt gtttctttta ggattcggaa ctttgctatt cgttcagacg ataatgaacg
    14881 tgggaagtat cgcggggctg atgccaatga ctggtgtgcc attgccattt gttagctacg
    14941 gaggaacaag ttatctgatc ctttctttag gaatcggaat cacgttgaat atttcttcaa
    15001 agatacaggc cgaagagttg gcgctctatc gacctgaaaa acaataaaga gaaactgaga
    15061 aactctcagt ttgaattatc ataaagtaca atcttttatt tttcaagcga gaggttcttt
    15121 tagaaagagg aattcgcaat gaaagtatct caaaaaatca tattatctat tttgttactg
    15181 cttacattag tagttggcta tttttcgatt gagtttatcc atggattttc gtctgcaaaa
    15241 cagagttcaa ctgtgaaaaa ggtagagccg aaaagtatcc ctaccacact aaatgtggct
    15301 ttgattggtt cagatgctcg ttcgaaagac gaaaacggtc gctcggattc acttctggtt
    15361 gcacaataca accagaaaac acaacaagca aaactgatct ctatcatgag agattcatat
    15421 gtcgatattc caggttacgg aatgaataag ataaatgcag cttactctta tgggggagtt
    15481 gatttattaa atcaaacatt aaaggaaaat ttcaaatttg aagctcccta ttatgcaagt
    15541 atcacatttc aagattttat cgattgcgtt aatgaactgt ttcctggtgg agtcaagatc
    15601 gatgcagaaa aatctctaga tttagatggc gtatatataa acaaaggaga gcaagtgatg
    15661 gatggtaata ctttactcca gtatgctcga tttcgggaag acaaagaagg agacttcggg
    15721 aggatcagaa ggcagcagca agtgatcaaa gctatctctc agcagctgaa agacgtaact
    15781 tcaatattca agctacccaa agcggttggg aaattacttg gtagtatcca aacgaacctt
    15841 ccagaaagtg tgcttctgga ttgtggtatg gatttcctca aagacatatg ttagaataaa
    15901 caggtataaa tagtgaaata aaggaatgac aagcaagaga aggaggaaaa aatgaaaaga
    15961 agtgacaagc acggcaaaaa tcgaacaggc gcttatattg ccggcgcagt gatcttaata
    16021 gcagctgcgg gtggcggtta tttttactac cagcactatc aagaaaccca agcagtagaa
    16081 gctggagaaa agacagttga gcaatttgtc caagctttga acaagggaga ttataacaaa
    16141 gctgcagaaa tgacatcaaa aaaggcggca aataaaagtg cattatctga aaaagagatc
    16201 ttagataaat accagaatat atacggtgct gctgatgtca aaggacttca gatatcgaat
    16261 ctaaaagtag ataaaaaaga cgattctact tacagttttt catataaagc aaagatgaat
    16321 acctcattag gtgaattgaa agatctttct tataaaggaa cattagacag aaatgatggt
    16381 caaaccacga tcaactggca acccaacttg gtttttccag aaatggaagg aaatgacaaa
    16441 gtaagcctga ccacacaaga agcagcaaga gggaatatta tagatcgaaa tggtgaacca
    16501 ttagcaacaa caggcaaact aaaacaatta ggagtcgttc caagtaaact tggagatgga
    16561 ggcgaaaaaa cagccaatat caaagcgatt gcttcctcct tcgacttaac agaagatgct
    16621 atcaatcagg cgatttcaca aagctgggta caacccgatt actttgtccc attgaaaatc
    16681 attgatggag caacgccaga acttccagct ggagctacca ttcaagaagt agacggcaga
    16741 tattatcctt tgggtgaagc agctgctcag ctgattggtt acgtgggaga tatcacagca
    16801 gaagatattg ataagaatcc agaattaagc agtaatggaa aaatcggtcg ctcaggtttg
    16861 gagatggctt ttgataagga tcttcgtggg acaacaggtg ggaaattaag cattacagat
    16921 gcagacggtg tagagaaaaa agttctgatc gaacatgaag ttcaaaatgg caaagatatc
    16981 aaattgacaa tcgatgcgaa ggcacaaaaa acagcttttg acagtctagg aggaaaagct
    17041 ggatcaactg ttgcgacaac gccaaaaacc ggtgatcttc ttgcgcttgc tagctctcca
    17101 agctatgatc caaacaaaat gacaaacggg atctcacaag aagattacaa agcttatgaa
    17161 gaaaatcctg aacatccatt catcagccga tttgcgacag gttatgctcc tggatctacg
    17221 tttaaaatga ttacagcagc aatcggtctc gacaacggca ctatcgatcc aaatgaagtg
    17281 ttgacgatca acgggcttaa atggcaaaaa gacagttctt ggggatctta tcaagcaacg
    17341 cgtgtcagta gtgatgtatc acaagtagac ttaaaaactg ctttgatcta ttccgataat
    17401 atatatgcgg cacaagaaac gttgaaaatg ggtgagaaaa aatttcgtac aggcttagat
    17461 aaattcattt ttggtgaaga ccttgatttg ccaattagta tgaatccagc acaaatttct
    17521 aatgaagata gctttaactc agatatcttg ctagctgata ctggatatgg acagggcgaa
    17581 cttctaatta ctcctatcca gcaagcagca atgtattctg tttttaccaa caatggcaca
    17641 cttgtctatc ctaaattgat tgcagataaa gagacaaaag ataagaagaa tgtcatcagc
    17701 gaaacagcag tacaaacgat cgtgccagat ctgagagaag ttgtgcaaga tgtaaatggt
    17761 acagcacatt ctctttctgc tttagggatt ccgttggcag cgaaaactgg tacagcggaa
    17821 atcaaagaaa aacaggatgt aaaggggcaa gagaacagtt tcttgtttgc tttcaatctt
    17881 gataaccaag gttatatgat ggtcagcatg ttggaaaata aagaagatga tgattcagca
    17941 accaaacgag catcggaact attgcaatac ctcaaccaaa attatcaata aaaaattgct
    18001 ttttaagtac agtaaaagga ctgtggcgtt atcgtcacag tccttttttc aaataaacgg
    18061 ttttcacgat gtctctttca caacttcttt ttgatttact cacacttcat aaactttttt
    18121 tgtaaaatat ttgagaacaa gtggagaaat aagtgtactt aataaaatca cgataactaa
    18181 aggtgaatag tactgtggtt cgatcaattg actttgctgt ccaatttgta aaatgatcaa
    18241 agccatttct ccacgcgaaa tcataccagc accgaccatc aatgaactat gttgagaaaa
    18301 accggcaatc tgagcaccaa aataacctcc aagcaatttg gtcaaaatcg ctacaagcgt
    18361 caatatagaa ataaagagta gttgttcact aaagtcagaa aaatcaactt ctaatcctac
    18421 actgacaaaa aatactggta taaatactgc atatcctaaa gcctctacat tgtggtatac
    18481 ttcttcttta acctttgtct gactgacagc tatcccagca aaaaaagcac caatgacaga
    18541 gctaagccca acaagatccg ctacgtaaga cattcctaaa caaataacta gcgatacgat
    18601 gataatagaa gaatttgcgt acactttttc tgcaaatgaa agtaggaaag gcgcaatcca
    18661 tttgactaat aagaaaataa aaacaaaata aattagctgt tcaatcaaaa caagcggtaa
    18721 agaagcattg ctagaagctt cccccgttag aaaagatagg ctgaaactta gaactaaaac
    18781 gactaaaatg tcatctacca cagaagcacc caaaattgtt gatccttctt ttgtattcac
    18841 tacgtttagt tcttttaata cttctactga aatactgaca gaagttgccg caagaataat
    18901 cccaaagaaa atcgcttcat ttcccgaaac ttggaatgct ttgcctgtca accagccaaa
    18961 aacaaccggg aagatgatcc caagcaaagc aacgaacata ccaggtcgga aatatttttt
    19021 caaaagagat aaatcacttt ccagaccagc taaaaacatt aataagatca caccaatctc
    19081 cgaaaagtca tggactagaa tatcaggttt gacccaattc aatccagctt ggcctagcaa
    19141 aacaccaaca agtaattgtc caatcactgc tgggatacct aatctccgcg agatatgtga
    19201 gccaatcgtt gttgaaatca atatcaggca taaaatacca ataaattcca ttctcatcat
    19261 tcctttgtat aaaatatagc ccgaacttag cataacatac attattgaaa aaataggaaa
    19321 atatactcac aaaaaaacca acaatccaaa agattttttt ggattgttgg tttttatacg
    19381 gtctatttta ataactaaaa atgattaacg tatagtcatt tttcttattc tgatgaaatt
    19441 gataatctcc tggatgccca tgaaaatcaa aataaagccg aatatttgga atagaagcat
    19501 caaacttttg aatggattga acaataagac gaatccgcca atcaacaaca gaatactact
    19561 ataaacactc caacttttag cttttgtatt catgctgaag aacaactgga acaagctgtt
    19621 gatgataaca gctaatccaa gaagaatcgg caggatagaa acgattgcag gtgcaaaagc
    19681 atagacgatc agagctaaga tcaggaaaaa aagaccactg aacagaccga tactccaaga
    19741 acctgttttc cttttaaaac ggtaagcctc aaaaagattc aacaacccaa gcaaaacaag
    19801 ataggcggtg atcagataac cgataaaatg aaaaacagca gaagggttta gcacaatcgc
    19861 aatcccagaa ataatataaa cagcagctct taataaggcg tatttttgaa tattttgttt
    19921 aatcgtctca aacatataag aaaacctcct ttgacttatt ttaacgtgaa ctagtcattt
    19981 taccaaatta aatgttacaa aatgagcgaa ggagaagaat atctctggaa aaatcaactt
    20041 ctgaggatct tttccatttt tttgcctttt gctagctcat cgatcatttt atctaaataa
    20101 cgaatttctt tcatcaagtt atcctcgatg tcttctactc gtacaccaca aacaacacct
    20161 gtaatcaagg aacgtgaagg attggggaca ggggcttccg caaaaaattg ttcgaaagtc
    20221 acttgttttt gtagttgata ttctagttct gtttgggaat aacccgtcag ccaacaaatg
    20281 atttcatcta cttcctcttt tatacgatct tttctctccg cttttgctac atacatagga
    20341 taaacgcttg caaaacttgt cgtaaaaata cgattttgcg ccataatcag tcacctttct
    20401 ttttttcaaa ttatttacta cttatagtat ataagaaaaa gagaagaaaa agcgattatt
    20461 caaaaaaaca aaaaggattg tgacaaaatt cttgtcacca tccttttttc cgctctctga
    20521 ctttttacaa tcttcatagc tcaagtgcgc atcagataat cgaatgctcc taaagctgca
    20581 gtagctcctg aacccattga aacaatgatt tgtttgtatg gactatctgt acaatcacca
    20641 gctgcgaaaa cgccggggat attcgttgcg ccatttttct cggtcactat ttcatttctt
    20701 ggattcattt cgatcgttcc atctagccaa tccgtattag ggagtaagcc gactagaatg
    20761 aatactcctg aaacagctag tgtatgcatc tccatcgtac ggcgatcgat ataggagaga
    20821 gattctacct gattcgtacc gctgatttct ttcgtcgctg catgtttgat aacagtgaca
    20881 ttcgcaagag agactagttt atcctgtaag atttgatctg cttttaattc tggtaagaat
    20941 tctagaacat atacatgttt tgctaaccca gccaaatcga ttgctgcttc aacaccagaa
    21001 ttaccaccac cgataacagc aatctctttt cctttaaata aagggccgtc acagtgtggg
    21061 caataagcaa ttcctttatt tttaaactct ttttcgcctg gtacattgat agaacgccag
    21121 tgcgcacctg tcgcgatgat ggcggttttt gctttaagtg atataccgtt agctaagcca
    21181 atattaataa aatgttgctc tttatttaag gaaacggcct gttgattcat cataatgtcg
    21241 atagggtaac tacgcacatg actttctact tgctgcatca attttggacc ttctgtgtaa
    21301 gaggtaccaa tcatattttc aatccctagt gtttcaacga cttgtccgcc gaaagaatca
    21361 gcgacaagtc ctgtacggat tcctttacgt gctgcataga tagctgcact actagctgct
    21421 ggtccaccgc caatcactaa tacatcataa ggttcttttt caaacaactc ttcttcaatc
    21481 aaagggccag tgattttttc aacaatttgt tcgatcgtca tgcgtccgct actaaattct
    21541 tctccattta aaaacacagt tggcactgcc atgatttttt tatcatcgat ttctttttgg
    21601 aacatcccac cttcaatcat cgtatgagta atatttggat ttaatacagc taatatattc
    21661 aatgcctgta caacgtcggg gcaattatga caagtcaagc taacataact gtcaaaatgc
    21721 aatgtttgtg ttattttttt gattttaaga ctcaaagatt cactgatttt cggtgcccgt
    21781 ccactaattt gtaacatagc cagtaaaaaa gaggaaaatt catgaccgag ggggatacca
    21841 gcaaaaacga ttccactttc tttgccaact ggattgatag aaaaactagg tgtgcgcatc
    21901 gaatctcttt tttcccaaga gattttagga gacatttctg ctatttcctt cgtaaattca
    21961 gctagttttt gactattttc actattatcc aaactaacag aaaaaacaat aggagattca
    22021 atcagtgcta aatattgttc gagattttgt ttagtttctt tgtctaacat atccaccacc
    22081 taaatctttc caacaagatc aaaacttggt ttcaatgttt cgccactttc tttccatttt
    22141 gccggacaaa cttcacctgg gtgggtacgt acatattgag cagcgcgaat cttatcaatc
    22201 agtgcactag cgtcacgacc gattccatct gcattgattt ccatagcttg aacgattccg
    22261 tctggatcaa taataaatgt tcctcgctga gctaatcctt gctcttcatc caaaacatca
    22321 aaaatacgag aaatctgatg agacggatca ccgatcatca cgtattcgat tttaccgata
    22381 gcatctgatg tatcatgcca tgctttgtga gtaaagtggg tatcggtaga gcaagaaaag
    22441 acttcaacac ctaaagattt caatgtactg tattgttctt gtaagtcttc taattcagta
    22501 ggacaaacaa aagtaaaatc agctggatag aagcaaagaa tactccagtt ccccataaga
    22561 tctttttcac tgacttctaa aaattctcct tgatgataag catgtgcatt aaattcttcg
    22621 atttttttcc caatcaatga catagtaaaa cctccaataa taattattta tttataatta
    22681 ttgtaattta gttggagttg caaagtcaat ggatattttg ttatttaata aagattactc
    22741 aaaaacgaag gttaattata aaaatagaag aggtcgcaag aaaatgctac tgctggaaat
    22801 actcgggata acgttgagta acagtttcct gttctttcag catcatgtgt aagtgcaatc
    22861 ccgtttgaaa tcgagcttct tctggttttt tatcaactaa agccttgagt aaatcataat
    22921 gttgttccat gatcgtttcc catggaagcc cctgaatggt cactcgtaac cagcggaaac
    22981 gttctaaatg ggtattatgg tcatctaacc agttccaaac ttcttttctt cctgcaattt
    23041 cgaaacaagc ttcatgaaat aaattatctg cacggaaaaa agcgcgttcg tcatttattt
    23101 tgactgcttt ttcttgttct tctaaaatcg tttctagcac tattcgtgtt tgtgtgtcca
    23161 atttggaaca acattcaatc atgatttgct cttccaactg ttctcggaca aagcgagcat
    23221 tttctgcaga aacaagatta attttggaaa catacgtacc actttgaggt atcgtataca
    23281 cgagttcttg ctgacgtagt tgaatcaatg cttcgcgaat gggagtccgg ccgatagcaa
    23341 gatgttcctc cagtgccttt tcagatattt tccttccagg ttctaagtca gcatagataa
    23401 tttgtttacg aatcgcttga taagcttgtg attgcaagct gcttttcatc tttattcctc
    23461 caaaatcatt tctatgaacg tagtataaca gaagaggtct gaaaaacaat ctggtatgtc
    23521 acattaacta gtaaatttgt ataaatagta aaattttggt tgacatagcg atttttattg
    23581 cataaaattc acttgaatac aaaaactaat atgttagttt aggaggggaa aaatgattga
    23641 tttaaacaac tggaggaact ttatccctga attatctcaa aaagaagtag aaatacctca
    23701 ttttgaccgt gcatcattaa gagaaaatgg acaaaaaaat cctgtctgga tccatttcgg
    23761 tggcggaaat ctttatcgag gatttcatgc agaaatcgct caacgtttag cggatctagg
    23821 cgaattgtcc actggtgtca ttgtttgtga aacattcgat gaagaaataa ttgaaagggc
    23881 ttaccaagat tttgatgatt tgattcttga agtggtcatg ccaagcagtg gagagttcgt
    23941 caaacgtata ttagctgcga cagctgacag tctgtattgt catccagatt gttctgaaca
    24001 ctttgataag atgattcgac actttgaaaa tcctagttta caattagtta cttttgctat
    24061 tactgaaaaa ggttatcgat tgaaagatac aaataataaa tatataggac cgattgcagt
    24121 cgatataaaa aatggtccaa agaagccatc acatacaatg agtattcttg ctgtgctact
    24181 ttataaacgt tttttatctg gagcttggcc gattgcactt gtctctacag ataatttttc
    24241 acaaaacggt agtcaattac gtacttcttt gctaacgatc gcaaaagaat ggcaaaagga
    24301 aggttatgta caaaatacat ttatccaata cttatcgaat gaagaaattg ttgcgtttcc
    24361 atggacgatg attgatcgta tcaccccgaa tccttccttg tcagttagca aaatgttggc
    24421 aaaagagggc ttttcaaata tgtcgatttt ccaaaccgca aaaggaaata atattgctcc
    24481 atttgtcaat acagaggaca tccattattt aatcatggaa gatcattttc ccaatggacg
    24541 tccgaaattc gaaaaagctg gggtattctt gactgatcgt gcaacggtag ataaagcaga
    24601 tacgatgaag gtgacgactt gccttaatcc tttgcatacg tctttagcta ttatgggttg
    24661 tttactgggg tataggagca tagctgagga gatgaaagat ccagatttat cgctgctagt
    24721 ttctgaaatc gggtacaatg aaggcctccc agttgtggag tctccaggta tcattgatcc
    24781 aaagatcttt ctggaagaag taattactgt gcgcttttct aatccaaata ttcctaatat
    24841 gcctcagcga atcgccacgg atacctctca aaaggtggcg attcgttatg gtgagacgat
    24901 taaaaaatat atggaaatag aagttaaaga cccgcagaca cttgtattca taccattgac
    24961 tctcgctgct tggcttcgat accttattgg cattgatgat caaggaaaac cattcatccc
    25021 gagtccagac ccactattga cagaccttca gcataagctt tccgatattc aactgggtac
    25081 gcaagataca tcacatattc atgagaaaat ggctcctatt ttgtcaaata aagaaatttt
    25141 tggtgtagat ctttaccaag cagagcttgg cagaaaaata gaagaaatgt tcatcaagat
    25201 ggtagcagga ccaaatgccg tacgaaaaac attacaggat tacttacaag aacatggagg
    25261 aaatttatca tggaaatgac ttttagatgg tacggatcac aggaagaaaa gattacctta
    25321 gatgaaatca gacagattcc tgcggtcaaa gggattgtag gcacattgat ggatatacca
    25381 gtaggagagg tatggcctag ggagaggatc aaagaactaa aagaagaaat tgagtctcgt
    25441 gggttaacac taaaagtaat tgaaagcgtc aatgtgcatg atgccattaa aattggatta
    25501 ccttcccgtg agcagtatat cgaaaactat aagcagacaa tccgaaactt ggcagaatat
    25561 ggaatagaag tcatctgcta taattttatg cctgtatttg actgggtgaa atctgacctt
    25621 gactaccgct tagaagacgg ctcatccacg ttagctttta tatctgatga tattccagat
    25681 gatccaagag aaatcgtcgc gcgcatcgaa cattccagca atgaatttgg attgccggga
    25741 tgggaacctg agcgcttagc tcctatcaaa tccttgcttg aagcctatgc atcagtagac
    25801 gaagaaaaac ttcgagaaaa ttttgcctat tttctccaat caatcatccc aacatgtgaa
    25861 gaggtagggg tcaaaatggc tgtacatcca gatgatccgc catactcgat ttttggatta
    25921 gctcgaatcg taaagaatcg agaagattta gattggttgt gtcgcatagt agacagccct
    25981 tataacggaa tcactctttg tacagggagt attgcagaag atccagaaaa tgatgtatat
    26041 gggattttag cagaattttg ccaaagagat cgaatcccat ttgcacatgt tcgaaatatt
    26101 aaatttttag ctaatcgaga tttctatgag gcaccacata aatccgaata cggttcatta
    26161 gacatgtacc gcatactaaa aacaatgtat gacaacggat ttaacggata catccgtcct
    26221 gatcatggaa gaatgatctg gaatgagaca ggaagaccag gatacggctt atatgatcga
    26281 gcattaggtg ctgtttatct aaatggatta tgggaagcaa tcgaaaaagg aaacaaaagt
    26341 aaagataatt agtgaaaaaa actgtaattt tattatgtaa ataagaagga tgttcaaatt
    26401 cttgatacat aaatccggag gttgttaata agcattcgga tttatgtatc ttatttggtc
    26461 taggaagtaa cttgattttc ttttttcgat tgatccatga gtgcttcttc ttttaattca
    26521 aagatatatt ctgagatcct cataatcact tttttccagt cttctggtgt gatgattcct
    26581 tttaaaatat agattttttt gatatgagaa ggcaattgtt tcaaagggca gtcgctgata
    26641 acgatgttgc agttctccat aaaatcattt tgtattttga tcgattcatt tgaaaaaatt
    26701 tgttctatct taacgatcag atctttactg atataaaaat cacgcgtata gttcacacca
    26761 atcacaattc gcggctgttt tttgtagcga tcatacaaat gtactaggtc ttcaaccatc
    26821 cattgcacat tttccttttc taaaataact ggtaacaagt gttgattttg ttctctgaaa
    26881 tccatataaa attgttcaat ggcggtttgg acttctttca atacgctatg ttcttgataa
    26941 agcatgaaag taggaagggg cgtatttggt tgattgaagt taagaaatcc attataaagt
    27001 ttatttcgtg cgaatgccaa tgagtaaaga atcttttctt tttcaggtat aaacaaatca
    27061 aatacagtac aaagggactc caccatttct cttgaataaa gaacatgagg aacgtttgct
    27121 ttttttaaaa gtttgtattg ctccaagctt gtttcttccg attcgatttt cgtgatagaa
    27181 agtcgagcta aaatattcac taagatgcgt tgttcgcgac aaattggcag attaggtcgc
    27241 aaaatatcta cagagagatc aataaaaaag tcaatatatt catactctgt gaattctttt
    27301 tgtacgtctt tcacagaagt tgcaggaaaa ttctctttac atatttttaa tagaaaatat
    27361 aatttatcta tcataccgct atttagtcgg tcaagtactt cttttttaaa aaaagtattc
    27421 atcataaaag ccactacttg cggatcttca tcataaaatt ctgtagcagt acttgaaaag
    27481 atgttccaat aaatatctaa tgctgcatat tgaatttgta cctcttttcc agaaaaagac
    27541 tttctgccat tattagaaaa ggagatagac aaaccgtact atgctaaaaa tgcattaatc
    27601 tttttcattt tcgtatacaa ataagaggca ctatagtttg tttgctgact gaaactgata
    27661 atcgaatttg tctgacagct gaacaaagaa gtcaagatct gataactgac tgattcgttg
    27721 cagtatcttc caaatagacg ataatagcag taagccggat caattccttc aaaattcaac
    27781 tttaaaaaag gtttttgctt atcaatatgc agttctgtta gattgagacg ctcaaagtct
    27841 tgttctaatt ctttgatgta tagtaaaaaa tttgattcag acatatggaa atgatctgct
    27901 aaatattgtg tagtaataaa gaaacgatgt tcagatagga aaagaaaaat atctaatttt
    27961 gtattgcttt ttttcttcaa gataaacgtt ttaatcgctt cttgagtttg catgaaagag
    28021 gctccttttt acttaaattg ttaaaacttg aaaatattac tgtttttttc ataaatttag
    28081 acaaaaaaac agtaaacata taggtagaat ctctactatc ttatttcttg catacaaaaa
    28141 aatcaaggag tgagagagtt atgagatatt caaccatctt aatatcaaca tttgcagcct
    28201 taagcttatc gcttactata aatcagacag tccacacaga ggagacagaa acagccaaat
    28261 ggacagaaac caagtgggcc aacgtcaatc gaattacctt tcaggatgaa ttttcatcct
    28321 tcaattcagg agtcgcaaaa ttaagaaaag gacaaacagc gaccatcaaa gcaaaaattg
    28381 actattcggg agacttagca cctatactac aatcagctgt tacatttgag aatgttgatc
    28441 ccactttgtc gattggctat gacgagaaca ctttgactat ccaacacaag caagcgatat
    28501 ttaccttcac cgttacatta aatcaggact tgttaaaacc agcgcttttt actgtcaagg
    28561 tatcagatgg actaccgaac gatcatcatt taacgccgta tagtcagcgg cagacaattg
    28621 agcaagattc agccatcgac tcaggaggag atcttgttga agaaccaaca gataaaccag
    28681 aaaatgaaaa taagccagaa gtaccgccta cagaaaatcc agacggagaa cagaaaccgg
    28741 aaatagaacc tggagaagaa cccgatacag aaactcaacc agagccagac aataaatcaa
    28801 aacctgaaat aacccctgga gaaaaaccag atgtaactcc agaaccagat acggattctg
    28861 gaaaccaaac agtaccggaa acaaatccag acacagataa tgaaactgaa aatccagaaa
    28921 aaccagaggt agatccagaa gaaaaaccag atgtgactcc agaaccagat acggacgcaa
    28981 gagaccaagg aataccagaa aaaataaaca aaaaaacaat tcaagaggat ggaaaaaaag
    29041 agagtaaaaa atcaaatcta gcaattctaa aaataaatga agagcagctg aataaaaaat
    29101 cacgaatatt tgatagcgcc caatcagctg aaaccttaaa aagtagcaag gatacaacct
    29161 ttgctgtcct gaaacgaaaa ataaacagct accaaaatcc ggagagtcac aaaacaaagt
    29221 tatactgtgg agcggaatca ttctattaag tatagcaaca atgctttctg caaaaagatt
    29281 taaacaaaac agatctctct aacatttgaa taatgtctgt gaacgcattt ttcaaataaa
    29341 aagaaatatc cagaaaatga ccccaaaata ccagattgaa atctgatatt tggggtcgtt
    29401 catactttat ctttcttcat atttatttta agggatatct gtttcttttg gaagatggtt
    29461 cgggatcttt ttcactttca atacatctaa aaagaaggta aagatcggaa tgccgacaat
    29521 caagccccaa acgccaaaga accgttcgct aacaagtaag accacaaatg tataaaaaat
    29581 cggcagttct gttttgctgg acatcaactt cggattcagc acataagact caattagatg
    29641 gacaatcaaa atcgtaatca ggatataaac aacatctcgg atgcctcctt gggaataagc
    29701 tatgaaagat agaggaatac aagaaatgat aacacctgct actgggatca gacttaaaat
    29761 gaaaatcatg atcgctaaac tcagcagctg atgaaagcca aatacagcca aggcgattgt
    29821 agtgagcaac gtatttaaaa gagcgacaac aaattgagct tctaatacca aaccaaatgt
    29881 attgacaaac ttatcggcaa aatagtaaat atcttgaaag aaccaagaaa attcactttt
    29941 taaaaacaat cttgagaata caattgtttt tttcttttca atcataaaaa agaaacttaa
    30001 gatgaatgac atagcaaacg ccactgccat ttttcctata tcctgtaaat agccaagcgc
    30061 aatcgaagcg ccattttgaa gctgttcaaa aaaatcgttt cgctcaatat aagtatggat
    30121 atattgtaaa acaggatctg catcttttgg ctgatgctcg taaaaattaa taacggactg
    30181 gatcatgtca aatgtttgat gaataagcat cgggatatac tttgtgaatg ccagatagat
    30241 aaggtaaacg atcagtgtat aaatcatgat agctaaaaca cctgtaggga ttcggacaaa
    30301 tcgctgaatg atttgaacaa gatgaatcat caaataagta aagataaatg tgagcaaaat
    30361 ggttgtaatc atacttctaa ctaagaaaag aacaaaaacg acaaataata aaacagtgag
    30421 acggcgtatt ttttcattcg ccaaaaaacg ctgataaacg gtcaaatcga caacctccaa
    30481 ataacaaaaa ataaacacgt tattcattat atgatggaat atgaaaataa gaaagagcaa
    30541 aaagaaaaac cgctaaatga cgttatctta tgagttggtt ttcctcataa aatcgttcat
    30601 ctagcagttt cagccctttt tctggtcttg atgaaaatta tctagcattt ttcgggtcag
    30661 atgttgcagt gtatccaatt cttcctgttc aagtggaaga taagacttga tcttttgtgg
    30721 aataccttct gcttgttttt gcaacgcagc accttgagca gtcagcgtaa catttacgat
    30781 tctttcatca cccgtttcac gctgacgatt aatataattt ttttctgcta acttttttag
    30841 taagggagtc agcgtaccag aatccagaca caaatcattt cctagctctt tcactgaagt
    30901 ctttttcttt tcccataaaa ctaacatcac aagatactgg gtataggtaa gattcagcgg
    30961 cttgaggagg ggagtgtagt gtctaatgat ttctttagag gcggcatata aaggaaaaca
    31021 tacttgatta actaaatata gatcttccat ttttccacct ccgctgtttt actatagtgt
    31081 atcatagcgg atttacacaa aaaagtctat tcactaactg ctttcagagt aacttctata
    31141 tttccagctg tagcttttga atacggacac actttatgcg ctgcctctaa taattcttgc
    31201 gtttcttcca gagaaagacc ttcgatagat ccttcaatct ctacacctaa gacaaagctc
    31261 gtttcacttt ctgaataaag ggaaacttgt gcactgacag tagaagcccc agagatattt
    31321 ttttgctgtt tgatcaattc taatgcactg ttaaaacatg cactgaaacc agctgcaaac
    31381 aattgttcag ggttggttgc attttcgacg cgtttaccat gagctgcaat attcaattcg
    31441 aatgtacgat cgggattatg cacttctcca gagcgtccgc ctgtgttgat cattttcgta
    31501 gaatacattt ttttcataaa attaccacct ttaattatat tttatacaat tgaattttac
    31561 acaatataat tgtggaaagc aaagaaatgg attggcataa gataaataag agaaagcaca
    31621 tgaaacagac gcgctttctc gaatagcaaa catatacaaa aaatatcaga gacaaaaaat
    31681 aatctcatca taaacattac atatatttct caaaaagttg ttttctttct tcaaaaatta
    31741 cttcacgatg gacctgatga agcatccata aataaccaaa aggatctctg aacattgagt
    31801 tagtcacacc aaagtccatc atttctgtca tttcttgaat ctctacacag ccatttcgta
    31861 atgctttatt atgtgtgtcc tcgatatcag agacgatgat attgaaccag atcgtatttg
    31921 gatgttcagc agtaggagca gtcaaaccaa gagacgtgtt ttcatccagc atatggaatc
    31981 tcgtaccata caaggtaaaa atgacttcat tattgcctct agggtaatct gttgcctcaa
    32041 tcagttgtat ttcatcaaag attgtttgat acagttctag tgctttcaaa ctatcattta
    32101 atacaaaatc gatttccgtt cctttatgca taaagatctc ctctcctttt cagtcgaaca
    32161 gttactagat tcttttatta taccagctaa agaaaacgca ttcaaaaaaa tagcggattt
    32221 acttaccaac tcattcgatt ggatgataag taaatccgcg tcccattact tctgctacgc
    32281 tgctgacaat gacaaaggca cttggatcga tttcttctat caatggtttc attcgggaaa
    32341 attcatgatc agtcacaacg atcaataaaa cctcttttga ctttcgatta tacccgcctt
    32401 ttgcctctag cagggtaagg ccacgtccaa tctcagcact taagcgaagg cggatgtctt
    32461 ccaaataatg ttcactcatg accataacag atttctttcg attgatacct gtttcgatat
    32521 aagtcatgac aattgaagtg attgcaatag ataaaatagc ataaagaaac tcttctattc
    32581 caaaaataaa cagattaaga gaaacaacga atgcgtctgt aaaaaataag ccaatcgaag
    32641 tattcaagtg gaaatatttt ttaaaaatga ggggagggat cgtcgtaccg ccgctagaag
    32701 agttgttttt atataaaatc gcaactccta aagcaaaaat cgcacttcca aaaatgacag
    32761 acaacaaccg atctgaagta atcattgttt ctggaactat tgcaatgatt aaaggaaaaa
    32821 ccaagcttcc gaaaagtact ttaaaaaagg gttttttacc taaaaataga agagctagta
    32881 ccaacataac gatattcaac actaaaataa ctatagctcg gtcaaagcct aaagcagctt
    32941 ccagtaatat tcctagaccg ctgacacctc cagcagcaat atgatgaggc cctaaaaaca
    33001 tattgatagc gactcctaat atgaagaggg caaaaataat cttaatgtat gtccatataa
    33061 attgtctcgt ttctttcatt tattcacttc cttaattcat taataatact cttatcttat
    33121 tataacttac ttttcacctt aagttaactt taattaataa aaaaattagg ctagtctaaa
    33181 ttattatgtt tcattcttct agaatatact tctacgccaa aaactgttaa aaaactttta
    33241 ctttagaaaa ttggagaaat tgatcgctta agataaattc aggacactaa atagtacagg
    33301 aagtagacta aaacttttaa aagttttaag tctatctatt tggcaagttt aaaaaataaa
    33361 aattcggtat caaaaaactg ttaccgataa catttttgaa agcgttgtct tttgcttctc
    33421 tatcacttat agtgatgacg tcatattaaa acacaaggag gaaatcaatg gatacagctg
    33481 caatttatca tcgaccggaa agtgaatatg catttctata tacgaataca agatttcgta
    33541 ttcggcttcg tactaggaaa aatgatatca aaaaagtata tgtgctatgt ggagatccat
    33601 ataccataac aactgaaaaa tggtatcaaa aacaacgacc aatgaaaaaa tgtctaagta
    33661 ccaatgttca tgattattgg gaaattgaag tgacgagcga aacaagtcgc ttacagtatg
    33721 cgttccatgt tgttggggaa gataacacgg actgttttta cggtgatcaa ggaatttttc
    33781 cttatcgaga aaatgtgatt actgaaccaa atttttattt tcgaatacct tattttcatc
    33841 aaatcgatcg attcactatt ccagaatggg taaaagaaac agtatggtat caaatttttc
    33901 ccgaaagatt tgcaaacggg gacaaagcaa atgaccccga acacacttta ccttggggaa
    33961 gtaaagatcc agaccgagaa gactttttcg ggggagattt gcaaggtgtg atggatcatt
    34021 tggattactt gacggacctt ggcatcaatg gcatctattt ttgtcccata tttaaagcca
    34081 catccaatca taaatacgat acgattgatt attatgaggt ggatcccgct tttggcgata
    34141 aaaaactttt aaaaaacttg attgatgaag cacataaaag agggatacgt atcatgttcg
    34201 atgctgtatt caatcatatg ggtgtccatt caccacagtg gcaagacgtt ctcaaaaacg
    34261 gagaaaaatc gatctataaa gactggttcc acatccgttt tttcccagta gattcttatc
    34321 agatgactga cttaccagaa actgctgaaa atatcccata tgatactttt gcttttactc
    34381 cattcatgcc gaaactaaat acagcaaatc cagaagtgca aaaatatttg ctggatatcg
    34441 caacttattg gataaaagaa ttcgatattg atggatggcg tcttgatgtt gctaatgaag
    34501 tcgatcatca tttttggaaa aaattcagag aagcagttac agaaatcaaa ccagacatct
    34561 atatccttgg agagatttgg cattcctctc aagcttggct gcaaggggat gaattccatg
    34621 cagtgatgaa ttatgcattt acagattcga ttaaagatta ttttgcaaaa aagaaaatca
    34681 cagcttcaca aatggtcagt ggaatgaatc atcagcaaat gctttacaga gatcaggtga
    34741 acgaaggaac attcaactta ttagattctc atgatactgc caggatcttg accctttgcc
    34801 aaggtaacaa agaattgatg aagtctgtga tggcctttat gtttcttcaa aaagggtctc
    34861 cttgtatcta ttacgggaca gaaataggga tgactggtga agatgacccg gattgccgca
    34921 aatgtatgat atgggagaag gaggaacaag atctagagct attcggtttt ataaaagaac
    34981 ttgtttctct aaggaaacag ttgtctaaga ttatttctga aggttctact cagtggctaa
    35041 tagtaaatga tcgtgaagat aagctctatt tcacacggaa actagaggga cagatcatct
    35101 atgtttactt taatcagtca aaagaacctt gggtagtaga acaggaaaat gaggtgattc
    35161 ttagtcaaaa ttgtcagttg ttagaagacg ggaaagcaga gatacgacaa tacggatttt
    35221 tgatcatgtg ttgaaaactg ttaccggtaa caacaagaaa gcgtttgcaa atgaagattt
    35281 gtgcccatta taataagggt gtaacagcac gttgaataca aaggaggaaa tgaagatgaa
    35341 aaaaagaagt gtgaaacagt tgggtttagg gttaatctct ttaggaatct taggcggatt
    35401 agcggcttgt ggcaatggta actcttcagc agaaggggaa gccgatgaag gaaaaacgtt
    35461 aacagtttcc gttgattctg gatataaaga ttatataaac gaaataaaaa acactttcga
    35521 aaaagaaaac gatgtgaaaa tcaagctagt agaaaaggac atgttcgatc agttggaatc
    35581 attagcgtta gatgggcctg ctggaaaggg acctgacgtt atgatggcag catatgaccg
    35641 gatcggtgcg ttaggacagc aaggacatct ggcggaagta aaactgggaa atgaagcagc
    35701 ttacgatgaa acagacaaag cccaagtgac ttatgatgga aaaatctacg gagaacctgc
    35761 agtaatcgag acccttgttt tgtactataa caaagattta gtcgatacag caccatcaac
    35821 gtttaaagat ttggagaatc tatccaaaga cagtcgtttt gcttttgagt cagaagcagg
    35881 aaaaaataca ggatttttag ctaaatggac tgacttttat tattcctatg gtttaattgc
    35941 aggttacggt ggctatgtat ttggtgatga tggcacaaat ccttcagata tcggtttgaa
    36001 taatgcaggt gctgtagaag gaatctctta tgcaacagat tggttcaaaa atgtttggcc
    36061 aaagggaatg caagacataa aaagtgcagg agacttcgcc agccagcaat tcatgtccaa
    36121 taaaactgca gcaatcattg acggtccatg gcaagcgcaa acatacaaag aaaacaatat
    36181 caattatggt gtagccaaaa ttcctactct aaataatgga cagccttatc aaccgtttgg
    36241 cggaggaaaa ggatgggtag tcagcaatta tgctaaaaac aaagacctct ctcaaaaatg
    36301 gcttgattat gtaacgaatc aggaaaatca agaaaaattc tttgaaatgg taaatgaaat
    36361 ccctgcaaac caacaagcta gggaaacagc aaaggctaaa aacgatgaat taacaacagc
    36421 tgtgattgaa caatatgaaa cagctcaagc gatgccaaac atcccagaaa tgggcgaagt
    36481 ttggacaggt gcagaaaact tgatgttcga tgcagcatca ggttcaaaaa caccaaaaga
    36541 atccgcagat gaagcagtaa aaacaatcag tgaagccata gaacaaaaat actgattaaa
    36601 atgataaccg tccattttta taaaaaatgg aacaggtgct tcagataaaa gtggcaagag
    36661 cgagatggaa aattatcttg ctcttgttgc cattatctta aaagcagttt gcggtttagc
    36721 aagtttagag ggggcattca gatgcagcaa gataaaacaa gcaatatcaa cgaaaaaaaa
    36781 atcacgcttt gttcacttat tccagggatg gggcagtttg taaatggcca agcttttaaa
    36841 ggtatcgttt ttttcgccat attcgtccta ttcattggtc agatgcttct gggcggattt
    36901 catgcattgg taggattggt tactttggga agtataccaa tggaagatca ttcattattt
    36961 attttgattg aaggcacttt gcaattcatc attacaatca ttttcttgat tttttacggt
    37021 ttgaatcttt tagacgctta tcgagtagcg aagatgcgtc aagagggcaa aaaaatcaat
    37081 cggacgatga aggaagtcat acataatata ggtgatgaag gttttcctta tctattgaca
    37141 cttcccgctt atcttctcat gatttttacg atcattttcc cagtcctagt tacattgttc
    37201 actgcattta ctaattatga cttcaatcat attccaccag ccagtttaat tgattgggta
    37261 ggggctaaaa acttttttag tatcttcttt ttaagctcat atcgtaatac tttttttgca
    37321 gtcttttcgt ggaccgtgat ttggacttta tgtgcaacaa ctttgcaaat cacccttggt
    37381 attctcacag cggttgttgc tcaccagaaa tttattaaat tcaaacgtat tttcggtatc
    37441 attttcttat taccatgggc ggtcccagct tttattacta tcatgagttt ttcgaatata
    37501 ttcaacgata gcgtaggtgc catcaatact caagtgattc ctttcataaa ccagcttcct
    37561 tttgtagata tcagtgcaat ctcttggaaa acggacccga actggacgaa agtagcaatt
    37621 atcttagtgc agggctggtt aggatttccc tatatctatg tgatggttac aggaatctta
    37681 caatcgattt cagaagactt atatgaagca gcaaaaatcg acggagcaaa tgcatggcag
    37741 cgcttttcaa acatcacgct tcctgctgtc ttcctagtgg cagcgccaac atttattaca
    37801 cagtatacgg ggaatttcaa taatttctcc atgatctatc tgtttaacaa tggcggtccc
    37861 ggaagcgtag gcggaggagc tggttctact gatattctta tttcctggat ctataaactt
    37921 acgactggaa cttctcagca gtattctatg gcttcagcaa tcacgttgat tatctccgtc
    37981 atcgttatct gtgtgtcatt gctggtattt aaaaagacaa atgcgttcaa tatgggggat
    38041 taacaatgaa aaaatttcat tcgagtgctc gattccaaaa acgactttct cactttttta
    38101 cttacttttt tcttttaata ctgtcagtca ttatcatcta tccgcttttg atcacagcaa
    38161 gtactgcctt caagtcagga aatattgcag cttttagttt agatctttca agtgactgga
    38221 ctttaggaaa ctttactcgg ctattcagtg aaacacttta cgggacttgg tataaaaata
    38281 cattgatcat ttctgtccta acaatgatcg tacaagtgac tgtagtaact ttggcgggct
    38341 atacttatag tcgctatcgt tttatcggcc gcaaatcaag tttgatgttc tttttagtga
    38401 ttcagatggt accgactatg gcagcattga ctgcctttta tgtcatggct ttcttattag
    38461 aagcgctcga taagtactgg ttcttgacaa tgatctatat aggcggtgga attccaatga
    38521 atacttggct gatgaaagga tactttgaca ctgtaccaat agatttagat gaatctgcta
    38581 aacttgatgg ggcagggcat ttcaggattt ttttccagat tgtattaccg cttgtcaaac
    38641 cgatgctcgc cgttcaagca ttatgggctt ttatgggacc ttttggggat ttcatgttag
    38701 ctaagttcct gcttcgaaca cctgaaaatc agactgttgc tgtcggctta caaacattta
    38761 tttctgatgt gacaaaccaa agagtctctc tttttgctgc tggggcaatt ttgattgcac
    38821 taccgatttg tctattattc ttctttttac aaaagaactt tgttaccggc ctgacatctg
    38881 gcggaacaaa aggataggag cagagtatca tgcaaacatt tccgttaaac tatttttccg
    38941 cattacgtac gccaactcaa gtgtttgcgg gacgcaaact attatcatgg cctaaatttt
    39001 tcttgatatt tgtattttta gtttccttga tggtcatgcc tgtgactctt ttttatgcca
    39061 atcagatcca agcgattcca ttagaacaat ttctatccgt tcattcgctg atcgatgaac
    39121 aaggaaccca aaaattttct gaacttgaat tatctgaaac tgggttacaa gcatcgcaac
    39181 aaacgatagc tgtgacccct gaaattttgg taggtgtgtc tttatctgag aaacaacaat
    39241 ccgatcatgg aacttttatt gattttgaga aggaacaatg ggtgatccaa caaaaggata
    39301 aatctggtat acgccgctat acgatgaatt atagcccatc tttccaacca gattctgtac
    39361 gtacgcccga agatttccaa cgatttttag aaagagaatt ttatgccagt aatcgtccaa
    39421 caatcatttt atcttatagt ttaagtcttg gtcttgtcct atttgtcatg acgagtctca
    39481 ttttattcgg ggcttccttt ttcttgtgga tgacaagaaa aagccaactt tcatccattc
    39541 atacattcaa agagagtgca aatttgatgc tgaatgttat gggaataggt tccatggcag
    39601 cagcagttgt agggtttatc cactttgact ttatcttgat gctaagtgtc caaacaacga
    39661 taactgtctt gctgctttta tgggtttttg tcaaaacaag attcaaagat aagcgtgtcg
    39721 aatgacaagt ttaagcgatt tatgcgacaa tgaatgtgaa aaaaatgaaa aataaagtag
    39781 tttttgaaaa atttctgaaa aaattaaact tcttagttga ttcttttctt ttttagtatt
    39841 aacgtaatag ggtagttttt ttaaggagga aaatcatgtt agagaaaact ttatacaatc
    39901 aattattttc acgttctttc tcgctccctg tcgaagtaaa ttattgggac ggtacaacga
    39961 aacaatacgg agatacggac actcctcccc aaatcaaaat caatatccat gaagaaatcc
    40021 caatgaaaga gattacaagt aacgcatctt tggcactagg agaagcctat atggatcatc
    40081 gaatcgagat cgagggaagt atccaagcat tgatcaacga tgcttatcag caagcaaaca
    40141 gctttttacg aggaaaagat tatctaaaat ggctgccaaa gaaagaaaaa catacgaaac
    40201 aaaaaaacaa agaagatatc catgcgcatt atgacttagg taacgacttt tataaacttt
    40261 ggctagatcc aactttgact tattcttgtg cttatttcaa tacacctgaa gatacgttgg
    40321 aacaagcaca aatcaataaa gtccatcata tcttagacaa actctttatc aaagaaggcg
    40381 aaacgttgct tgatatcggt tgtggctggg gaacattgat gttcactgct accaaagagt
    40441 ataatgtcaa ggcaactggg atcacactaa gtgaagaaca atacgatttg attaccaaaa
    40501 gaataaaaga agaacattta gaagataaat gccgtgtatt attaatggat taccgcgaac
    40561 taaaaggcga aacgtttgat catatcacaa gtgtaggtat gttcgaacat gtaggttctg
    40621 aaaatcttga aggttatttc aaagtggtaa aagatttatt gaaaccaaaa ggaacagctt
    40681 tgatccatgg aatcagccga caacaaggcg gtgcgacaaa tgcttggatc aataaatata
    40741 ttttccctgg cggttatgtc cctggtgtta ctgaattagt tgataatatt acaaaaaacg
    40801 atttgcaact gattgatttg gaaagcttac gtcgtgacta ccaattgaca ttagaacatt
    40861 ggacaaagaa ttttcatcaa gtccaagatc aagtcacgaa agaaatgggt gattccttct
    40921 atcgaatgtg ggatctatat ttacaagctt gtgcagcttc atttgaatca agtaatatcg
    40981 atgtgattca atatttgctt gttcaacctg gaaacaatga catcccaatg catcgtgcat
    41041 aattgaggca aaagtactgt ttaaagacta tttaaaaaga agctaagttt tatgatgctc
    41101 cagaagtgaa cttttttgtc taacttctag gattgtctct aaagcttagt ttc
//
LOCUS       DARPZF010000020        40371 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.020, whole genome shotgun sequence.
ACCESSION   DARPZF010000020 DARPZF010000000
VERSION     DARPZF010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40371
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.020"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(162..2159)
                     /gene="tkt"
                     /locus_tag="SLE65_001381"
     CDS             complement(162..2159)
                     /gene="tkt"
                     /locus_tag="SLE65_001381"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEI8448684.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2261..2512)
                     /locus_tag="SLE65_001382"
     CDS             complement(2261..2512)
                     /locus_tag="SLE65_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEI8448685.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2659..3282
                     /gene="lexA"
                     /locus_tag="SLE65_001383"
     CDS             2659..3282
                     /gene="lexA"
                     /locus_tag="SLE65_001383"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HEI8448686.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3462..3680
                     /locus_tag="SLE65_001384"
     CDS             3462..3680
                     /locus_tag="SLE65_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448687.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3969..4481)
                     /locus_tag="SLE65_001385"
     CDS             complement(3969..4481)
                     /locus_tag="SLE65_001385"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEI8448688.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="SLE65_001386"
     CDS             complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="SLE65_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEI8448689.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6934..7377)
                     /locus_tag="SLE65_001387"
     CDS             complement(6934..7377)
                     /locus_tag="SLE65_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HEI8448690.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7378..8166)
                     /locus_tag="SLE65_001388"
     CDS             complement(7378..8166)
                     /locus_tag="SLE65_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8448691.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8163..9104)
                     /locus_tag="SLE65_001389"
     CDS             complement(8163..9104)
                     /locus_tag="SLE65_001389"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEI8448692.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9281..9868)
                     /locus_tag="SLE65_001390"
     CDS             complement(9281..9868)
                     /locus_tag="SLE65_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HEI8448693.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10089..11396)
                     /gene="obgE"
                     /locus_tag="SLE65_001391"
     CDS             complement(10089..11396)
                     /gene="obgE"
                     /locus_tag="SLE65_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEI8448694.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11690..12700
                     /gene="gap"
                     /locus_tag="SLE65_001392"
     CDS             11690..12700
                     /gene="gap"
                     /locus_tag="SLE65_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEI8448695.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12785..13720)
                     /locus_tag="SLE65_001393"
     CDS             complement(12785..13720)
                     /locus_tag="SLE65_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEI8448696.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            13906..14865
                     /locus_tag="SLE65_001394"
     CDS             13906..14865
                     /locus_tag="SLE65_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HEI8448697.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(14951..16045)
                     /locus_tag="SLE65_001395"
     CDS             complement(14951..16045)
                     /locus_tag="SLE65_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEI8448698.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            16234..16995
                     /locus_tag="SLE65_001396"
     CDS             16234..16995
                     /locus_tag="SLE65_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEI8448699.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(17110..17550)
                     /gene="fabZ"
                     /locus_tag="SLE65_001397"
     CDS             complement(17110..17550)
                     /gene="fabZ"
                     /locus_tag="SLE65_001397"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEI8448700.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            17770..18525
                     /gene="fabI"
                     /locus_tag="SLE65_001398"
     CDS             17770..18525
                     /gene="fabI"
                     /locus_tag="SLE65_001398"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HEI8448701.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            complement(18635..19648)
                     /locus_tag="SLE65_001399"
     CDS             complement(18635..19648)
                     /locus_tag="SLE65_001399"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEI8448702.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            19813..20733
                     /locus_tag="SLE65_001400"
     CDS             19813..20733
                     /locus_tag="SLE65_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEI8448703.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            complement(21013..21513)
                     /locus_tag="SLE65_001401"
     CDS             complement(21013..21513)
                     /locus_tag="SLE65_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEI8448704.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(21620..22138)
                     /locus_tag="SLE65_001402"
     CDS             complement(21620..22138)
                     /locus_tag="SLE65_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEI8448705.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            complement(22139..23494)
                     /gene="rph"
                     /locus_tag="SLE65_001403"
     CDS             complement(22139..23494)
                     /gene="rph"
                     /locus_tag="SLE65_001403"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HEI8448706.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            complement(23497..24318)
                     /gene="racE"
                     /locus_tag="SLE65_001404"
     CDS             complement(23497..24318)
                     /gene="racE"
                     /locus_tag="SLE65_001404"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEI8448707.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            complement(24480..25136)
                     /locus_tag="SLE65_001405"
     CDS             complement(24480..25136)
                     /locus_tag="SLE65_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEI8448708.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            complement(25152..25799)
                     /locus_tag="SLE65_001406"
     CDS             complement(25152..25799)
                     /locus_tag="SLE65_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEI8448709.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            complement(25812..26627)
                     /locus_tag="SLE65_001407"
     CDS             complement(25812..26627)
                     /locus_tag="SLE65_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEI8448710.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            complement(26641..27378)
                     /locus_tag="SLE65_001408"
     CDS             complement(26641..27378)
                     /locus_tag="SLE65_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEI8448711.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            27632..28642
                     /gene="trpS"
                     /locus_tag="SLE65_001409"
     CDS             27632..28642
                     /gene="trpS"
                     /locus_tag="SLE65_001409"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEI8448712.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            complement(28812..31232)
                     /locus_tag="SLE65_001410"
     CDS             complement(28812..31232)
                     /locus_tag="SLE65_001410"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEI8448713.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(31237..32280)
                     /gene="pheS"
                     /locus_tag="SLE65_001411"
     CDS             complement(31237..32280)
                     /gene="pheS"
                     /locus_tag="SLE65_001411"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEI8448714.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            complement(32589..32930)
                     /locus_tag="SLE65_001412"
     CDS             complement(32589..32930)
                     /locus_tag="SLE65_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8448715.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            complement(32999..36721)
                     /gene="addA"
                     /locus_tag="SLE65_001413"
     CDS             complement(32999..36721)
                     /gene="addA"
                     /locus_tag="SLE65_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEI8448716.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            complement(36718..40245)
                     /locus_tag="SLE65_001414"
     CDS             complement(36718..40245)
                     /locus_tag="SLE65_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HEI8448717.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
BASE COUNT        11436 a         8670 c         7046 g        13219 t
ORIGIN      
        1 ctcaagaaac acaaactaat ccgaagaatt ctttgttttg tcatttaaat gtaacatagc
       61 cgaaaacgaa aagtaatatt gatttattct tctaacacat aaagaacagc tgtctccaac
      121 ttgcagacag ctgttcttat cagtcaaaca attgcttgga tctatgatag ttgattgtac
      181 gtattcacga cattttctac tgtaaatcca aattcttcta aaattttagt gccaggggca
      241 gatgcaccga aatgatcgat tgtaatcgtt gcgccctctg ttcctacgta gcgttcccat
      301 ccaaatgatg cagcagcttc gatagccaca cgtttcttca ctgatttagg aagtacactt
      361 tctttatatt cagaagattg tttttcaaag aggtcaaagc ttggcataga aacaacagaa
      421 acatctttgc ctttttcagc caattctttt tgagctttca cagccaaatc aacttcagaa
      481 cctgttgcaa tcaaaatacc ttctggtgtt tctccttgtg atggagaaag aacatacgcg
      541 ccttttttca ccatttcatc tgctacttct tttgtagaag gcaatactgg aaggttttga
      601 cgactcaata caaggatagt aggcgcatct gttgtctcca tcgctacttt ccaagcagca
      661 cgtgtttcat ttccgtctgc cggacgaatc acttgaacac caggcatgca gcgaacagat
      721 gctagttgtt caatcggttc gtgcgttggt ccgtcttctc cgacagcaac cgagtcatgt
      781 gttaagacgt aaacaacagg agtatgttgg attgctgcta aacgaactgc tggtcttaga
      841 taatcgacaa agacaaagaa tgttccaccg tagatacgag ttccgccatg aagttggata
      901 ccattcatag ccgaagccat tgcaaattcg cggacaccga accagatgtt gcgtccttca
      961 taatgttcag gagtgaaatc tttatctgca gccaccattg tattattgga acctgacaag
     1021 tccgctgaac caccccagaa gcttggtata gctttcgata attcttggat gacttcttta
     1081 cttgaaacac ggcttgcttg actgcttcca acttcataag ttggcaattc tgcatcccag
     1141 ttttctggta gtttgccatc aaaagcatct tcaaattgtt gtgctaattc aggataagct
     1201 tttttataat tggcaaacat ttcattccat gcatcttcag ctttttgtcc ttcttctatc
     1261 atcgtttgat ggaagcgggc agctacttct tctggaacag tgaaatctgg atactcccaa
     1321 ccataaactt ctttagccat cttgatgcca tcttcaccaa gaggagcacc atgaacagca
     1381 gatgttcctt ctttaggagc accatagccg atgactgttt ttacttcgat caatgttggt
     1441 ttgtctgttt cagcttttgc ttcttcaatc gctttagaga ttgcttctag gtcatttccg
     1501 tctttcacta agatatgttg ccagccatat gcttcatagc gagcaccaac gttttctgtg
     1561 aaagcttttg aagttggacc gtctagtgaa atatcgtttg aatcgtataa aacgatcaat
     1621 ttccctagtt tcatatgacc tgccatcgaa cttgcttctt gagatacccc ttccatcaag
     1681 tctccgtcac cgcatattgc atacgtatag tgatccatca cattaaagtt ttctttgtta
     1741 tacgttgctg caaggtgcgc ttctgccatt gccataccga cagccattgc aatcccttgt
     1801 cctaatggcc ctgtagtggc ttctacacca tctgtatgat gtacttcagg atgtcctggt
     1861 gttttagaat cccattgacg gaattgtttc aaatcatcga ttgtcacttg atagccagct
     1921 aaatgaagca agctatacaa cattgctgac ccatgtcctg ccgaaagaac gaaacggtcg
     1981 cggtcagccc agttttttga tgtcgttgga tttactttca ggtgttttgt ccataacgca
     2041 tatgccatag gtgctgcgcc catcggcaat ccaggatgtc ctgagtttgc tttttggact
     2101 gcttcaatac ttaatgtacg aattgtgtta acgccaagtt ggtcaatttt gtcaaacaaa
     2161 ataacccctc ctattaattt aggttttttt tacctttatt tcttacactt tcattctata
     2221 agatgtcaca cgaaaaagca atctttttca gtatttttta ctaaaagttg tcatttcggt
     2281 tgtgtaagcc ttttttcttt tggatttctt ttaatttttc cggggtcacg tcattgccct
     2341 caggatcgac gactttcatt ccttcgatat gatgacgcat accggaacga aaagcttcca
     2401 aatactcttt gcgcaagttg atttgttctt gttcttcggc ttttgagaga ccattttcct
     2461 tctttttacg tgcaagttca ttgatccgct ctattttttc aggtgacagc atgctcagcc
     2521 ctccttttac tctccttcat attatataaa aactgaaaaa aaaacaacta gataaactaa
     2581 ataaaatacg aacattcgtt tgatttagcg ctttttatat ggtactattt atttatcaag
     2641 tgaaagaagg tgtaccttgt ggcccgacaa actgaatcaa gacaaatcga agtcttacga
     2701 tatatccatg aacaagtaac ccaaaaagga tacccgccga ctgtccgtga aatcggggaa
     2761 gctgttcagc tttcttctac ttctactgtt cacggtcatc ttgcacggct tgaaaaaaaa
     2821 gggtttatcc aaagagatcc gacgaaacct cgtgcaatcg agttgacaaa acaaggttta
     2881 gaaaagattg ggattcgtcc aacaactatt ccagtacttg gcgtcgtaac agctggagaa
     2941 cccattttag cagtagagga tgcttcagac ttctttccaa tccctcctaa tctttcttcc
     3001 gaagaaggca gtctctttat gctgacaatt cgtggagata gtatgatcaa tgctgggata
     3061 ttggatggtg acaacgtgat cgttcggaag caagaaactg ctcaaaatgg cgatattgtc
     3121 attgcaatga ctgccgagga cgaagcgact tgcaaacgat tctataaaga aaaaaacttt
     3181 ttccgtctgc agcctgaaaa cgacttgctc gaaccaatca tcttagatca agtatctata
     3241 ttaggacgag tagtaggact ttatcgtagt catatctatt aattgctact aattaaaaga
     3301 aaacttttta aaaagagttt gagacgttgg tctcaaactc ttttttcgcc cgggttcttc
     3361 ttctttcaaa tttttatcac ttccctcttt acaaaccgaa caaatattcg tatactaaat
     3421 atacgaacaa ttgttcgcat aaattaaaga ggtgagaatt catgaaatca atgagacgtc
     3481 ttggcttagt attaactgtt ttgtttttag gtattattat tggtaatttc ggcatacgtc
     3541 cagctttact tgtgtttgtt ccgttattta ctttgtggtt catgttgtgg gatgaaaaga
     3601 agtaccgtca atctgagcgg cgcagaattc atgaagatca tttctatcat gagccctact
     3661 acagatccag gcaatcataa taaggattga ctgctaatta ttcaaaagac aagaagttaa
     3721 acttttacgg gggtgtgaca aaaatcggtc acatcctttt tttcgaataa acggtgttct
     3781 aaagccagtt tttcggtatt aagtcaaatt gcggaaaaag tgatttttta aacttctact
     3841 ggtctttgct tgtttccatt tataaaaaaa tagcgaccct caaaagtcag atagagaatc
     3901 tgacttttga gggtcgcttt aaaatcgctt ctttaagaat aacatcaaga atagcttctt
     3961 ttttctgctt aatattccat taatgtaatg atgtcatatc ctttgatttt gtcgcgtcca
     4021 tggagatcca tcaattcgat caaaaatgcg cagcctacga ctacaccgcc taattgttcg
     4081 atcagttcga tcgtcgcttt gattgttcct ccagtagcta gcaaatcgtc acaaatcagc
     4141 acacgttgac ctggtttaat ggcatcctta tgcaatgtca atgtatctgt tccatattct
     4201 aatccataag tcacttcgat ggtttctcga ggtaacttcc cttttttgcg gactggggca
     4261 aaaccgactc ctaactcata agcaacagga catcctacga tgaatccacg ggcttctggc
     4321 ccaactacca tatcaattcg tttttctttt gcataattta cgatttgttt agtagcttcc
     4381 cgataagcgt caccatctgc catcagtggg gaaatatctc gaaacacaat tccttttgac
     4441 ggatagtcgg gaatactggc aatataatct tttaaatcca ctctttgttt cctcctaggt
     4501 tgttaaccat ttctttatgg taggaatatc gctcaaaagc aaaaattcct caactttgat
     4561 tttattgagc cgtcgctggt ataatctgct ctcagtcaaa ggatgacttt ctgggctagc
     4621 gactttttgt aaaacaccgt tctctattgt aacaaatttc aattcaaaaa acacctgtat
     4681 cataaaaatt aataattttt cagggatacg caaatattga gctattgctt ttattttatg
     4741 acgtatatca attcgttctt gagaatggat caatttaaac aattttgcgt actgttctct
     4801 tgtgcctacc ccattcaaat aggcctcatc aggtgaaatc cccatcagat aaacacgatt
     4861 gaatgaataa gaccgaaaaa cttctttcag atccgctaaa tcatctggac aatccataac
     4921 aactagagag tttggttttc ttttttcaat tattgccttt acagaatcta gtccttcgaa
     4981 aacaatcgca gcttcctgga taatctcagg cacgaatttc aacgtcgaag aatcaaatgc
     5041 taaataaagg ctaccttccg acgttcggct ctgttcacgg aaacgttttg cccgccaatc
     5101 aaatacttgc agaccaccca cagaaaaatc agataccatc agctgcggtt tcttacgccc
     5161 gttccattca ttgatcgaaa gctttcctac cacatctacc tgattattca gcagttcttc
     5221 ttcttgagta ccaaaaccaa aagcgaccgc atcaagctga ctcgatgcat cggaaaggac
     5281 aaatttcaga tgctgttggt ttgctccgat tcttttgata ttttctgctt ggacttgtcg
     5341 aaataaaaac tgaggcaaag gattatccgt accaaatggc gccaatagtt tcagctcatc
     5401 aattcgctct actgttactt catttggcag caatacttca tcaattctca actcaggccc
     5461 tctcatcaag tcaatttgat gatcgactat atattggttc atcttctcct gtagtatagt
     5521 gacattttca cttggcatcg ttaaaccgac tgctgcatga tgtcctccga agtaagtaaa
     5581 taaatctcgc atctggtcaa gcatttcaaa aagattcaag gcttcaatac tacgtccaga
     5641 tcctttagct gatccatctt cttttaaagt aaggacaagc gttggtttac ccgtttcatt
     5701 cattattttc ccagcaacaa tgcccaaaac gccttcatgc catcctcggt ttaccaatag
     5761 atggatatga ttctccttat tgaccatcgc taatgcttct tgtgttatct gctctacgat
     5821 tgcttttctt tcttcattga tctcattcaa tttttttgct tgaacggatg cttcctcttc
     5881 atcaaacgtc gcaagtaacg agacggcagg acgtggatcg cccatccgac cgattgcatt
     5941 tagtctggga gcaatcgaaa aaccgatcgt tgtttcgtct gcgtccctca tttttacgcc
     6001 gctttcttca aatagcgcct gaagtcctat ccgttctgaa tgatgaatgg catcgattcc
     6061 taatgaaaca aggattcgat tctcatcagt caatgaaact aaatcggcga tcgttcctat
     6121 cgctactaaa tccaaaaatt ctgcaggcgg ttcttccaat aatgcagaag ctactttgaa
     6181 tgctactccg actcctgcca aatctggaaa tggatagtgc cccgctggat gacgagggtg
     6241 aacaatcgca taagcgtctg gtaaattctc aggtagttcg tgatgatctg taatgatcac
     6301 gtctacacca gcttgctgag cgtatgctac cgcatcattt cctgctaccc cgttatcaac
     6361 agtgatgatc aactggattc cttcttcgat cttttcttgg tataccgatt ggtttggtcc
     6421 atacccatgc tcaaatcgat ttggcaggaa tacttctact tctgcaccaa gtaattccag
     6481 tgtttctttc attaccgttg cactggtgat cccatctgcg tcataatcac cgtaaacgag
     6541 gattttttct ccactgatta cagcttcttg gattcggctg attgctttat ccatatcgtg
     6601 tatcagatac ggatcatgta attcttgttc ctttggatgt aaaaatcggt tgatatcctt
     6661 ttcctcatgg taacctcttt gccacagtaa cttaccgaca aatggagata atttcagttc
     6721 acggatcatt tggagaaagg attcagaagg ctctgtctcg cttaacttcc aatcaaaatt
     6781 tgcttgtctc actttctcac tcctaactta gttattatag caaaggaaat cagcaaaaaa
     6841 aagcagaaag aaagaataaa aacagatcag atccgctaga cagatgttca gcaggacctg
     6901 atcttttgta cgaccattta tgaaatatcc ctattagtca aaataattga agctttgttt
     6961 gggcgattga gttttttgtt cttccggcgc tttcaattga ctgatttgtg cggttttcgc
     7021 ttgtaactcc gcctgataag cagcttccaa ctccgcacgt tcgtttctaa actcgcgttg
     7081 ctgttcttct tttgcttctt caattttctt ttgaagttct gtttgatatt ctgacatttc
     7141 ctgagtcagc tgtttgattt gctttttttg ctgccatagt gttgccgaag cagtcaaaaa
     7201 tacaatcagt gcaccaatca gcgcagaacc gatgatcact aagatcaatg gcgcagaaaa
     7261 ggaagtgaag ccaaaactta caggaacatt tttattgttc aatacagcaa aaagaacaat
     7321 aatcaaaact aaaacaaatc caagaatcac attgctttgc tttttcaatt ccttcaccta
     7381 ctttttgtta aaaattccgc tggctaaata atcaccaatc gttggaaaca gcgtataaaa
     7441 ttttgatgca acttctaaaa taaacggttg attgatttcc cgttttggat gtctcatatt
     7501 gcggacgatc atttttgcca acttggcagg ttctaaaacg atttgtccga ctttttccaa
     7561 atagcttccg cttggatcag ccttatcgaa gaaatttgtc tcgattggac ctggattcac
     7621 tgtcgtaaca gctacgccaa gtggtttcaa ttctaatcgc aaagcgttgg agaagccaag
     7681 gactgcaaat ttcgtggcag aataaaccgt tgattttgca gttgccattt ttccagccat
     7741 agaggcgata ttaatgatat gaccttgtct tctttctgcc atatcgatcg caaatttttg
     7801 tgtcaaaacc atcattccta agatgttgac ttcaaacata tcgtatgctt ttccaaggtc
     7861 gaatgtaagg aagtcttcga aaatcccaaa acccgcattg tttaccagaa tatcgacgcg
     7921 cccgacttct tccatcacct tttcatataa ttcgtccacg ctttcaggat tgctgacgtc
     7981 taccttgaaa gcataagcct ctttgccgct caagcgtctg cactcgtctc tgacaccttc
     8041 tacaaatgcc attcttcgtg cgcaacttat aacgattgct ccttgctttg ctgcttcata
     8101 acagatttgt gcgcccagac cgcctgaact acctgttact aaaacaactt tatcttctaa
     8161 attcatgcct cttcctcctc gcgaaatgga atctcaatgc tatcaaaatc tttcataatc
     8221 gtcgtgtttt caaacacttc ttgtgcttct ttttcaagct ctaaagctgc ttttcctaaa
     8281 tatctcgcac tgatatgagt aagtagcagc cgttttgcct gcgcttcttt tgcaacttca
     8341 gcagcttgat gagtcgtgga atggaaatag ttgtgcgcca ttcttgcttc atctttatta
     8401 aatgtgcttt catgtaccag aatatcgcta ttttccgcaa gcacaacgga attatgtgtt
     8461 tttctcgtat cgcctaaaat agtcacgatt cgtccttttt tatctggacc tacgaaatct
     8521 tttccattga tcgtccgccc atcttctagt tggatcgttt caccttgctt cagtttgccg
     8581 tacagtggtc cagctggaat acctaattct tttagacgat ccacctgcaa ttctccttta
     8641 tgatcatgtt caaccacacg ataaccaaaa ctgtcgatcc catgatttag tttttttgta
     8701 taaacagaaa attgctgatc agtaaaaatc ggggctgttt catttagctc aatgaatttc
     8761 agcggataac ttaaacgcgt ttgcgaaata cctaaagaga cttttatgta ttcctctatc
     8821 ccttttggcc cgtaaatctc taatggcgta tccccacctt gaaatgaccg gctgctgatg
     8881 agcccgggaa gtccaaaaat atgatcgccg tgtaaatgtg taatgaaaat tttaccgatt
     8941 tttctcggac gaatagtcgt tcgcaaaatc tgcatttgcg tgccttcgcc acagtcgaac
     9001 aaccaaactt cattgcgctc gtctaaaagt ttcaatgcta tacttgtcac atttctatgt
     9061 tttgcaggaa cacctgcacc tgttcctaaa aattgtaatt ccataatcta cctgactttc
     9121 tttaagttcc tctttaattt tagggtaaaa agaagggata atcaaccgta agtcgagaat
     9181 gggttcaaat taaaaataac gttctaaagc gatagcgttt tctttgaaaa ttactataaa
     9241 aacagcagcg aacccgtttg agatcctctg ctgtttttta ttaatttgaa gatccagaac
     9301 tttcattgtc gttggaagtt tgcggatgtt tgtccttcca agtcttttgt gcagcttctt
     9361 tcgcatgatt ttcagcttct ttcgcatcat gcacatcttt ttcgacatct tcataatcca
     9421 agcgagtaat ttctccgcct aattccatca ttaccaattg attcagtggg cgattgtcct
     9481 cttcatcagc aatcaagatc agtcctgtag ctccttcacc gattttattt cctacaaagt
     9541 cgaacacggt ctgggcatct tttatttctt tggcatcttg tgtcgcaccg atcattcctc
     9601 cggcaaacca tcctaataaa atccctagcg gaccacctaa tacaccaacc aacattccga
     9661 ttaatccacc cgtagaagat ttgttattac cggtaaagtc gataaaatct tctattttga
     9721 attgatgtgt cccattagga tcatggctga caactgccat ctgttctcct ttaatcgaac
     9781 gaacagcatg taactttttg atttctgaaa atgcctgata tgcctggctt tctacttgaa
     9841 aatttaaaat gattactcgt ttgctcatta aaaacgcccc tttcatacct tcttgttatt
     9901 tattttacct ttaattgaaa aataagaaaa gaaaagcact ctttttttcc aataaaatag
     9961 ggctgtgaca aaagtcgtat cacagctcct ttttccgaat aaacggcgtt cttgaagctg
    10021 atcacttctg tcacaacctc ccttaaatct gaatctatat tttttggtat ttgtttttat
    10081 ttgcttgcct attcgacaaa ttcaaattca aactcaccga tacgtacaag gtcgccatct
    10141 ttcgcaccgc gtgcccgaag agcttcatcc acacccatac cacgtaattg acgagcaaaa
    10201 cgcatcactg tttcatcatg atcgaaattc gtcatttgga ataatttttc gatcttctca
    10261 ccagataaga tccacgttgc atctgaatca cgatcgattt ggaactcagg accttctgga
    10321 ttgaatccat agtgtacagt ttcttcttcc agttcttctt cgtacaatgg gaattctggc
    10381 gttacttcta acaaatctgc tgtagcattc aataacgcgt ccaatccttg tcgagtcact
    10441 ccagaaattg gaaatactgg gatgtcatca gcaaattcat cttctttttc cttgttcagc
    10501 tgttctttga atttcactag attttccggt gcatccggca tatccatttt gtttgccacg
    10561 atgatttgcg gacgctctag caagcgtaag ttataagtag ataattcttt gttgatggca
    10621 agatagtctt cataaggatc tcgtccttcc atcccactca tatcgatcac atgtaaaatt
    10681 actcgtgttc tttcgatatg acgaaggaat tgtgtaccca gcccaacacc ttgcgaagct
    10741 ccttcaatca agcctggcaa gtctgctgcg gcaaaacttc tgccatcact tgtagtaacc
    10801 attcctagat taggtacgag cgtcgtgaaa tgataagcgc cgatttttgg acgagcagat
    10861 gaaataacgg atagtaaagt cgatttcccg acagatggaa aacctacaag tccaacgtct
    10921 gccaatactt tcaattctag ttcgattttt cgctcttgtc ctggttcacc gttttcagca
    10981 atttccggtg caggattccg aggagaggca aaacggatat tccctcgtcc accgcgtcca
    11041 ccttttgcca caactagtgt ttgaccattt tcaattaaat ctcctaaaag agcaccagtc
    11101 tccgcatctc ggacagtggt tccttgtggt actttaacat aggtatcttc tgaaccacga
    11161 ccgtgcatcc ctttactcat cccattttca cctggctgcg ctttgaaatg gcgattgaac
    11221 cgaaaatcca tcaatgtacg taacccttca tcgacgatca agatgacatc gccgccacga
    11281 ccaccgtctc cgccagccgg tccgccgtca ggaacgtatt tttcgcgacg aaatgcaacc
    11341 attccgtctc cgcccttgcc agctttcaca tcgatcgtta cttgatctaa aaacatggac
    11401 ataattaagt cctcctatta ttcatttatt tatttgactg cctgaatttc cacaataaac
    11461 aaaagtctta cttattttat cggtgaaatc tgattttgtc tatcatttca gcaaaaagat
    11521 tgtttacctt cttctttttt tatcatttgg taaggtttcc aacctttttt ctgctaccaa
    11581 gtataatttt ttgacaaaat attctttgcg tagcagaata acagtgtatt aattgtatta
    11641 attgaggatg ccgtttcaca gcacccctaa taaaggagga acttttgata tgacagtaaa
    11701 agtaggtatt aacggatttg ggcgtattgg ccgtctggct ttccgccgca tcaaagaagt
    11761 ctcagatgat attgaagtag tagcaatcaa cgacttaaca agtccaacta tgttagcaca
    11821 attattgcaa tttgactcta ctcatggtac ttatcctggc acagttactg caacagaaga
    11881 ctcaatcgta gtggatggcg aagcaactcg tgtttatgca gaacccgacg caagcaaaat
    11941 cccttgggca aaagaaaacg gtgtagatat cgtactagaa tgtactggtt tttatacatc
    12001 tgaagaaaaa gcaaaagcgc atttagatgc tggtgtcaaa cgagtagtta tttctgcccc
    12061 agctggtgct atgaaaacca tcgtctataa cgtcaatgat gatacattag atgaaaacga
    12121 caaaatcatc tcagcaggtt catgtacaac aaactgttta gcacctatgg cttatttctt
    12181 aaataatgaa tttgggatcg aagttggtac aatgacaaca gttcatgcct acacttccac
    12241 acaaatgctc ttagatggac ctgtaaaagg cggtaatttg cgtgctgctc gttcagctgc
    12301 tgacaatact atcccacatt ctactggtgc tgcgaaagca atcggcttag ttatccctga
    12361 gctacaagga aaattacaag gacacgcaca acgtgttcca gtcgttgatg gttcattaac
    12421 tgaattggtt tcagtattga aaacaaaagt aactgctgat caagtaaacg aagcaatcaa
    12481 aaaacacaca gttgacaatc cttcattcgg gtatgatgac cgtcaaatcg tttctagcga
    12541 tgtcattgga acaactcaag gttcgatctt tgacccaacg caaacagaag taacaactgc
    12601 tggtgatttc caacttgtta aaactgttgc atggtatgac aatgagtatg gatttacttg
    12661 ccaaatgatt cgcttactag aaaaattcgc taacttgtaa tttgatagat caatcgataa
    12721 aagaagcctt tgactggatc cagtcaaagg cttctttctt ttcatcccct acttttaaac
    12781 tcgttcaatg aacatattgg cttaaaaatt gttggactac ttgctgatat ttttcaggat
    12841 ctgtcttgta tgcttccgca tgctcggctc cttttacaac atacttttct tttggtccct
    12901 tcgttgcacg atagacctta tctaacattt caaatggtac aaatgtatct tcgtctccat
    12961 gtataaagag cattgggcgc tggtttttct tcaattgttc cactgcattt gcttcaccga
    13021 aaaagtagcc agcacggact tttgtcacta gactcgttac ttgcataagc ggaaatgctg
    13081 gaagactaaa catatcgtct agctgataag caagctcatc atgaacggaa gaataaccgc
    13141 aatcttcaat gattgctttc acattatctg gtagtttttc tccgctagtc atcataactg
    13201 ttgctgctcc catgctgaca ccgtatagaa cgatttcttg cgattttcca ttgttttcta
    13261 gcactttgtt tatccactgt acatagtctt tacgctctgg ccatccaaat ccaatgtaat
    13321 ccccttcgct ttttccatgt cctcttgcat caggaacaag gacattgtaa cccatatcat
    13381 gaaacatctt tgcgtaattg gtcatcgttt cagcgtttcc catatagcca tgagccacaa
    13441 gagctgtttt ttcacttttc gtttcagcag gaagataaat cgctgataat ttcagaccgt
    13501 cttttgaagt gatggtccaa tcgcttcggt tttcttttga actaaaccat ttatgtgcat
    13561 ccgtttcttt ggatgtctgt gttgtaccag gtgtatcttc gtctaaaaag tctttctcag
    13621 aaggcacaac agcataatta taaaaataat tccctgcaaa cactaacgca acaatcagag
    13681 ctaaagcgac gcctaaaagg attttcatcc aaagtttcat aaatcatcca tctcatttct
    13741 cttttttcat ataaccttga attagtataa tcaaagaatc tctactatgc aatgttcatt
    13801 tttataaccc gcgaattgta aaattaagtt agaaaaataa aaaggcattt atggtacact
    13861 caaattgtat ttccgacgaa agaaaacaaa ggagtgtaac cataaatgac ctacaaacat
    13921 cttaccatag acgaactgac aatgatagaa tcatattatc ttcaacataa taagccggtt
    13981 gaaatcgcta accgaatggg acgtgctata caaactattt ataatgtagt caataagttc
    14041 aagcaaggca agactgctct tgattattgg caccagtata aagaaaataa gaaaaaatgt
    14101 ggtagaaaag tcattcaatt acctgctcat gaagtagatt acattaaaga gaaagtcact
    14161 cttggttgga cgcctgacgt cattatcggg cgaaaagaaa ggtctgtttc atgcggtatg
    14221 agaacacttt atcgtttatt ttctaaagga atatttgata ttgacacact accgatgaaa
    14281 ggtaaaagaa aacccaatgg ccatcaggaa aaacggggaa aacaacagta tcagcgctca
    14341 atccatgatc gacctgataa ttatcctgat ttcaattctg agtttggtca ccttgaaggt
    14401 gatacgatcg ttggcattca tcataaaagt gccgtcatta ctttagttga aagattatct
    14461 aaagtcatta tcacgattaa acccaacggc cgtaaggcat tagatattga aactgccctt
    14521 aatcaatggt tttctcgctt ccctaaaaac ttctttaaat ctattacgtt tgactgtgga
    14581 aaagaatttt ctaactggaa agccattagt aaccaacatg atattgatat atattttgcg
    14641 gaccctggaa caccttctca acgcccatta aacgagaatt ctaacgggat tctgcgtcgt
    14701 aatggactgc cgaaatcaat ggattttaga aaagtgaatc agacatttat ttccagtgtc
    14761 agcaatcaac gtaatcatat tccaagaaaa tcattgaatt acagaacacc aatcgaaata
    14821 tttttgagct atgtacaaga agcattttat tctagcttaa tttgacaaat cataacctat
    14881 aaaaaaacaa aataaaaaag cagaaataac tggctatttc tagcggatta tttctgcaat
    14941 aactaattat ctatttttta ttttcaatta atttaaagct tgaccatggt ttcaaaaagt
    15001 caaggaggaa taattcgtca tcggagattc ttcctacaac attgacacgt ccgtcgtttt
    15061 tcatatcctt caaggcgatt tgtgtttctc ctttgtattg accgtaccct tcattgtcaa
    15121 tcagtacatc cccatgatgc atatctcgcg tattatgagg cgggaaatct ttatctttgt
    15181 agtatacacg agtcatcgtt gaacgaagga tatattctga gcgatcccct cgataactat
    15241 gaaggttatc aaacaagcag attcgttcgt tttctgtaat accttcttcc gtatctactt
    15301 tcaatgttgg ataatccgcg ttaaatgctt ctgccatttc tttcaattct tcttcacttg
    15361 cgtacgcatt tccaatagaa atatcatcaa tcaatcctgt aaggattaaa tgcttcactt
    15421 gtgtcgcaat ttcaagatct cggtggtctt ccagcgtgca caagccatct tgcgtaggcc
    15481 aagggccaaa ctcagcagat tgcgaattga cgaatgccat cgtattcaaa ttatattttc
    15541 tgaatttttc tgaacaaaaa acaaagtgtt cgtatcctaa accagagtat cgatgaggat
    15601 aaaaattatg agaacctaat aaattatccg tgtttggcga ataactcatg atgttgtcaa
    15661 cgtaattcgt gcccgaactc atattgatct cgattttgat accaaaagga ttgcgcgtca
    15721 tttttgcttc ttctgctcct gtgaatccga tatctaagcg gaccccgtag gcacccatct
    15781 tatggaaaaa agataagtca tcgtaagaaa tctccaactg ttcaaataac gctggattga
    15841 tatcaaccat tacttccatg cctaggctat tcgcgtaatc aactacttct ttaaattctg
    15901 aaagaacttt ttctttatca tcattgatct gcagcaaact ggtaaaaacc cgtttatacc
    15961 catacttatg agctaaatcc aagtacgctt tgtccttttc aaatgttgac cgttctggat
    16021 aaatcgagat tcctaatttt cccatattac catttcctcc tgcatctttt cgtttttgta
    16081 tccacttaca ttatagcaaa cacaaagtaa atggtctaca ccttttcttt ttcttttaaa
    16141 ataaatgata aattccaata atttaagtag gtattttccc tctattttgt tatcattaaa
    16201 gataacaaaa tagtaaattg gaaaggaaca gttatgaaga aaaataaagt tattttaagt
    16261 attagtttag cagcagcatt gctgtttgct gctggttgtt ctgcaaacaa cacgacttct
    16321 tctagttcgt ctacagaaag ttcaaaaagt acatctactg cggaaagcac gactgccagt
    16381 agcgtcgatt tgaacgcatt ggaattacca caattgacga aagatgtcgc cgaaaatgaa
    16441 gatctggtcg aaatggtgac gaataaaggc acaatcaaaa tcaaattatt tcccgaacac
    16501 gcaccaaaag cggttgaaaa ctttatgaca catgcaaaag acggttacta caacggactg
    16561 actttccatc gcgtcatcaa agatttcatg atccaaggtg gcgatcctaa aggcgatggc
    16621 actggagggg aaagcatttg gggagaagga tttgaaacag agatcaacaa ccacctttat
    16681 aatataagag gtgcgttatc tatggctcgc tcacaagatc ctaacagtaa cggcagccag
    16741 ttctttatcg ttcaaaatac agatgatatg catgatggtc ttttaaaaga cgactatcct
    16801 caagcaatca tcgacgctta taaaaacggc ggttatcctt cactagatgg ccattatact
    16861 gtcttcggcc aagtgattga aggaatggat gtcgtggatg ctattgcaaa tatcgaaaca
    16921 gatagttcag acaaaccaaa agaagaagta aaaatcgata aaatcaatat actgcaagaa
    16981 gcaaaacaaa aataaaaaaa taacgtctga atcctgcata gatgacaacg tatgctagga
    17041 ttcaggcgtc ttctttttac ataaaaagca agtaagcttc cttttgtttt gctatatcag
    17101 gttttatagt caagcatttt ggttgacgat gaacgtgaac tcgcactcac agactttttt
    17161 atcatctaca tatgctgcag ataacgctgt accgactgat cccttcattt tggtgatttc
    17221 aaaatgacat ttcagcacat ctcctggaac aactttttga cggaatttgg ccttattgat
    17281 cccaccgata taagctcttt ttcctagaaa ctcttctgat tttaggataa gtatcgaacc
    17341 tgcttgtgcc agtgtttcta gaatcaacgc acccggcatc actggattgt caggaaagtg
    17401 accttggaaa aaatcttcat tgattgttac attttttgtc gcaacgatct tttttcctgg
    17461 ttctaaagta tctacataat caatataaca aataggataa cgattaggaa tcaattccat
    17521 tacttcagta gcagataata cgtaagacat aattaaactc cttctttcag gcaattgcca
    17581 ttttcattac tttgactatc aaagtatcat attcctaaat atttagcaat ctttttttaa
    17641 tttaagaaaa aatagtttga caatcaaaac attttgacta ataattaaga aatcaagaag
    17701 ttattttagc tattattctc tattttttta cgactatcaa atttttatca gaaacaaagg
    17761 agagtcatta tgtcatttct agaaggaaaa aaaatcgtca ttatgggcgt cgctaacaaa
    17821 aaaagcattg cttggggttg tgctgaagca atgttgaaac aaggggcaga aattatctat
    17881 acttaccaaa atgaacgaat gaaaaaatca ttagtcaaat tggtcggcga agaagcattc
    17941 actgtagaat gtgatgtttc tagcgacgaa agcatcgaaa aagcaatgaa tgccatcggt
    18001 gaatatgctg gggagatcca cggccttgtc catgcagttg cttacgccaa caaagaagaa
    18061 ttgtccggaa atgtgtctga tatttccaga gacggctatc aattagctca agatatcagc
    18121 agctactctt taattgctgt atcaaaatac gcacaaccgt ttcttgcacc aaacagcggg
    18181 atcgttagca tgacttatct aggttcagaa cgcgcaatcc cgaattataa catgatgggt
    18241 attgcgaaag cttctcttga agctgctatc cgttatttgg cagctgagtt ctcgcctaaa
    18301 ggaattcggg tcaatggaat ctcagctggg gcaatcaaaa cattagctgt cacaggtgtt
    18361 aaagactatc aaaaactgat ccagttatct gaatctcgta cgcctgatca gcaaggtgtg
    18421 acgatcgaag aagtcggtaa tgcttgtgct ttcttaatca gcccactttc cagcggaatc
    18481 atcggtgata ttatctacgt tgacaaaggt gtccatcttt cataaacttt tgttgcattc
    18541 tttaaagtaa aacatataaa aatcaggaaa aaacttttta aagtctcttc ctgatttttt
    18601 ctttttacgt ttttttcaac tcattacttt gaaattattc cacgacttca atccagcctt
    18661 ctggtgcttc tatgtctcca aattgaatac ctgtcaattc atcatacaac cgttttgtta
    18721 ctggtcctac ttccgtttca ctataaaata catgaagatt gttattgtga taaatcccac
    18781 cgattggaga aataacagcc gctgtaccac atgcaccagc ttctgcaaat tgatctagat
    18841 catcaatgaa aatatctcct tcaattgctt gcagtcctag tcgttcttca gctaactgca
    18901 acaaggaata tttcgtgata cttggtaaga tagagggcga ttgcggagtg atgaattttc
    18961 cgtcttttgt aattccaaag aaatttgctg cacctacttc ttcgattttc gtatgtgtgg
    19021 ctggatcaag ataaacacaa tctgagtaat ccagttcttt tgcttctgtt cctggaagta
    19081 aactcgctgc gtaatttccg ccgacttttg ctgcaccagt ccccttagga gcagcacgat
    19141 cgtaatcaga tacaataaaa ttcgttggtt ttagtccacc tttgaaatac gctcctactg
    19201 gcgtacagaa gacgacaaat aaatattctg gagctggatg gacaccaatg ttttcaccga
    19261 ccccaatcag taaagggcgc aagtataatg tagcgcctgt tccatagggc ggcacaaaat
    19321 cttcatttgc ttttaccact tgcttgacag catcaacgaa catcttttca gggaccattg
    19381 gcatcagcaa tcgtctagca ctttgattca tccgtcgact attttgttca ggtcgaaaga
    19441 gattgacctt gccgtctttt cgacgataag cttttagacc ttcaaaacat tgctgaccat
    19501 aatgaagcgc tggagagcct tcatgaatcg tcaggtaatt atcttctgtc aattctcctt
    19561 cttcccattg tccgtctttc catttggcaa taaaacgcca aggagttttg atataagaaa
    19621 aacctagatt gttccaatcg atttgcatat acttaccacc ttcgttattt tctccacatt
    19681 ttatcattat ccatattatt tgtcatttta ttttcagctt ttttccttca ttatagttat
    19741 ttttgctatt tccttttttg aaaacttctt ggtacaatac agaaagaatc aaattttaga
    19801 aaagaggatt ttatgttttc attattagca actgccggta cgacagactc ttctggcgag
    19861 acattgacag atcaagctgt cagcaaagta aatgcgtttc agcggttttg ggacgggatt
    19921 gattgggacg ccattttggc tgcctttatc caaaaaagtt tatatctgat ttttttgatc
    19981 gtcctttttt ggattcttca ccgtgtggga aaatatctga ttgataagtc ttttaatcag
    20041 tattctaaaa aagccattct aaacgagagc cgcttaaaga ctttacatag tcttttaaat
    20101 actatttttc attataccct tggtttcttt tttatctatg caattttatc tgctatcggt
    20161 gtgccgatcg gatcactttt ggctggtgcc ggaattgcag gtgtggcaat cggtcttggt
    20221 gcccaagggt tcatgagtga tgttattacc ggatttttta ttatcatgga acaacagatg
    20281 gatgttgggg actacatcaa gctagcaaac ttaacgattg aaggaaccgt cgtatctgtt
    20341 ggtatccgta cccttcagct gaaagcaacg gatggtactg tccatttcat cccgaatcga
    20401 aacatcacca cgatcagcaa tctctctcgt gcaaatatgc aagtactttt agatattcgg
    20461 attgttcctg aagaaggata tgacaaaatc tatgagatca ttgatcgagt aaatcgtaca
    20521 ttagctgaaa aataccaaga agagctccaa actgaacctt ctatctttgg attagtggat
    20581 cttggaaaca gcaattttgc gattcgtacg gtctgctacg cattgaacgg aaaacaatat
    20641 gccttaaaag aagagttctt gagctcctat gtcaaagaat tgacagcttc tggtttcacg
    20701 attccgaaca gtccaattgc tgtcggaaaa taatttggac aaacgatgca acgaatctca
    20761 ctaaaaagag cgtgggacaa aagtaaagaa cacttttgtc ccacgctcta aacacgtata
    20821 aacggcggaa gcagaagcaa ctccttcgga aataagctga aattcacaaa aatttgaaaa
    20881 gcaattttcg tgaattcctt cttatttctt ggagttaaac gcttttgtcc cagcctcttt
    20941 ttcaagataa agtcaaaact ggtacgctgt tttttctact tattttttga ttatctttta
    21001 gtttctcgtt ctttagctca cgatatcgat ttgttctttt aattcttcga ttttcggaga
    21061 caatatatta cgacgttcta attcatgcac catgaagttt acggctttaa gcagctcttt
    21121 tcttgtaatg attcctttga aaatccgatc ttctgtgaca accggtaaaa aaggcgaatc
    21181 gactaacaaa tggagtactt cttctagttc ccaattttca tcaattgtcg gaacatctgt
    21241 ttctgtcaca tcagcaaccg ttagtccttc taacgggtcc atgctgattg tttgcaagtc
    21301 aatcatttta ttgaccacat ctgataaact tactagtcct acaaagtgat catcttttcc
    21361 taatacagga attttggaat aaccgacctt cgataacaca agtaaaccat gggacaatgg
    21421 atgatgatac ataacatttg ccacattttc tgcaggaatc aaaaacgttt cctgattttc
    21481 cagcagcatt tctcttacta taggtccaat catctgatgg cctccatttc tatttcattc
    21541 aacactacta ttttaccgaa accggatgca aaattcataa aataaagctt atttttatta
    21601 aaaattagag tttttttatt cagcgctctc tcgaaaaaga aaaggccaac tcttcaactg
    21661 cctgatgggc acggttatag tattgaacag aaatttggtc atctaaactt tcgataagag
    21721 catatgatgg gatttggatc gggcctctag gctgagaaat gctaccagga ttcaaaaaca
    21781 ggattttctg atccatctca cagcctattt gatgggtatg accaaaaaac accatatcgg
    21841 cagttgcagc tcgagcttcg attgctaact gtgtcaaacc aaatcggaca ttcgataaat
    21901 gaccgtgagt catgaatact gtatcctgac cagtttggat cacttttttc tgttcgaatc
    21961 ctggtccata atcacaatta ccttgaacca cttggaatgt atcccataat gggtcagaag
    22021 cttctaattc cgaatcacca caatggaaaa agatatccac ttcagaacga taacgatcta
    22081 ctaagtcaac gaggatatct ctgtctccat gattatcact tactactaaa taccgcatct
    22141 atctctctcc ttccagccat tgtttccact cggcactcaa ttttttcatt gcttgagccc
    22201 gatgactgat cttgtttttt tcttcgctcg ataattctgc tgctgtttgt ttcttacctt
    22261 ctgggataaa taaaggatca tacccaaagc cattttcgcc agatggtata cgggctactc
    22321 gaccgggcca ttccgcttct actacaaggc tgtctttttt gggtgccgcg aatactaacg
    22381 tacaatggaa ttgtgctgtt cttttttcat ccggcacatc tgtcaattca tataataatt
    22441 tggcgttatt ccccgcatca cttttttgtt cccctgcaaa acgtgcagaa tagattcctg
    22501 gcataccgcc taaagcatcc actttcaaac ctgaatcatc tgctaagact ggctgatcaa
    22561 gcaattgtgc aatcgtttct gcttttaatc gggcattttc ttcaaatgtg ctgccagttt
    22621 cttccacatc tggcaattca ggatagtcaa gtaatgtttt tacatgatat cccgcttctt
    22681 tgaacatatt tcgaaactct tctgcttttc ctggatttct tgtcgcaatg atgattgttt
    22741 ttgtttcttc tatccgctca tcattttgag caaactctgt tagcaaagca tgtttttgct
    22801 ctttgatcaa atcttcaatc gcgttttttc caaaaaagag catttcattc aactgttcac
    22861 catcaaacgt tgcttcttct ccagttcctt gaatctccac gaattttcca gattctgtca
    22921 ttacaagatt catgtctaca agtgctgcgg aatcttcttg gtaatccaaa tctgtgacgc
    22981 aagtcccatc tggtaagatt cctacgctaa ctgcagcaag atgttctttt attggatctt
    23041 ctgacaattc tttttctctt aaaagttttt caatggctaa tttcaatgcc acaaatgccc
    23101 cagtgatact tgctgttcta gtaccgccat ccgcttggat cacatcgcag tctacgatga
    23161 tactacgttc tcctaatttt tccaagtcta ctactgcacg caaggaacga ccaataagac
    23221 gctggatttc cattgttcta ccagaaagtt tccctttgct gctttctcta cgatttctcg
    23281 tactcgttgc tcgaggcagc atactatatt ctgctgtcac ccatcctgtt cctgtttctc
    23341 tcaaaaaagg gggaacagaa ttttctattg ttgcagaaca aataactgtt gtatcaccaa
    23401 aacggatcac taccgatcct tctggatatt tgaaaacatt tgtttgaagc tccagtttgc
    23461 gaagctcttg ggcttttctc ccgtcatgac gcatccttat tttcctccca attcgatatg
    23521 ttctacattt aagtgtccga ttccaagcca gtcttcagct atttcctcga aaagtttggc
    23581 agagccagtt gtataaaact ggcataatgt ccgaccattt tgcggtgaat tgctcaaatt
    23641 gaaataatct aacagcatag atacttcacc tactgtttct gctccagaat cgatcagttg
    23701 aacattttct cccattacat tttgaatgat ggggcgtaat aatggataat gggtgcatcc
    23761 caaaatcaat gtatcgattt ttttagtggt taaaggagct aatgtttctg ccacaatttt
    23821 tttcgccacc gatgaatggt attcattact ttcgacaact gaaacaaatt tgggacaagc
    23881 aagacttgtc acagtcaatt ctggtacttt ctctttcagt gctttttcat aagcttgact
    23941 ttttaccgta ccaatcgtac cgataatgcc aacttgttta ttttgtgttt tttttactgc
    24001 cgctctagta ccgggaagga tcacaccgat gactggaata gaaagagcag ctttgatttc
    24061 ttctaaagcc accgcagttg cggtattgca ggcgatcacc agcatcttga ttccttgctc
    24121 caccagataa tccgtcattt cccaagtata ctggattacc tgttccgcgg gtctagggcc
    24181 atatgggcag cgtgctgtgt ctcctacaaa taaaatattt tcattcggta attgtttcag
    24241 ggcttctttt actacagtca agccgccgac acctgaatca ataaatccga tagggcgatt
    24301 atctgtcaat cgtatcatcc tttttttcaa taaattctat cctccctatt gtgtactttt
    24361 tagcgtgaat tttcaagtgc tcttacttgc ttaaaacaat cgaaatctct ttttttcgaa
    24421 tggaaagagg aaaagcggtt gtgactttag tttgccacaa ccgctaaaag aatcatctat
    24481 taataactgt accgtctctt ttccaagtaa ccggaaagca gagaaagcgc gtaacatacc
    24541 acgaagtaca taagtgtcat gatgatgaac atcggaagca cataattggt gttctgtcca
    24601 taaataatac gtgcctgatg agaaagttca ggtaaagaaa tgattactgc taatgaagta
    24661 tctttgatca gtgaaatcaa ttggctcaca attgccggga tcattgattt aaatgcttgc
    24721 ggtaacacga tcgttcgcat cgattctaca taagtcagtc ccgttgataa tcctgcttcc
    24781 atctgtcctt ttggaacagc attgagtcca gctcggaaaa tttccgacaa catagctgac
    24841 tcaaaaatcg ttaatgctgc gacagcggac cagaagatgt tcatctgaat gccgatttga
    24901 ggtaaggcaa agtaagtgaa gaaaatgatc aataataatg gaagattccg tataatatca
    24961 atcactacac caaggatttt ggaaaagaaa gggatattcg caaaacgaat cacacctgtc
    25021 agaccaccga tcaagaaact aaaaatgatc gaaaacaatg aaacttcaac agtaaccttt
    25081 aatccttcca ataaaaaacg gatattcatc catgaaaaag cgccgctaaa atccatgtat
    25141 ttcccctcct tctatgaacg aaccgcccat tttttctcaa gataaaccat taagtaagat
    25201 aacggtagcg tgataactaa gtaaaataac ccaacgatga tatacgtatc gaaggtattg
    25261 aatgtttcac tagcgatcaa gtctccttga tacatcaaat ctaaaccagc tacgattgct
    25321 aaaatagatg agttttttac gaggttgata aattggttgc ctaatggcgg gataacgatt
    25381 ttgaatgctt gcggtaaaac aatataacgc atgatttctg aataggtaaa accagaagat
    25441 agtcctgctt ctgtttgacc ttttggtacg gtttgaatcc ctgaacgtac tgtttcagca
    25501 ataaaagcag atgtatagat cgttaatcca atcgtacctg cttggaatcc atctagatta
    25561 aaccaataaa tcggtacgac aacataaaaa aacatcacga tgattaataa tggaatgttt
    25621 ctaaaaaatt ctacatatgc ctttgctaag gcgctcacta ctttattctt tgataattgg
    25681 aagattgcca ttaacgttcc gataatcaaa ctaaacacaa gtgctaagac actcgaaaac
    25741 aatgtgatct tgaacccgtc gacaaagatt ggtccataag tttgtatcaa ttcgctcatt
    25801 gcctctcccc cttactctac ttttccttca gtttcatttg gaaaccattt ttgatagatt
    25861 ttatcgtatg tgccatctgc atgcatttcc tctagcgctt ggttaacagc tttcaagaag
    25921 ttttcttgcc ctttgttgat cgcaatcccg taaggctcat tagtaaacgt tccaccaact
    25981 aactcatact ctggattttc atctgcaatc cctaacaaaa tcgcattatc cgtagtcatc
    26041 gcgtctccct gaccagattg taaagcagta aatgcttctg catagttttc taattctaaa
    26101 atttttgcat ctggtgcatg ctgtcggata ttcgcagccg atgtagaacc tttgactgct
    26161 agaaccgttg tagaagcatt caaatcatct acacttttga tttggcttcc tttctttacc
    26221 aacaaagctt ggccagcatc gaaatagaca tctgaaaagt caacctgttt ttttcgttca
    26281 tctgtgatcg tcatcgttgc aataattgca tcgatatttc cgtttttcaa taatggaatc
    26341 cgagttttag aagtgacttc aacaaattct gtttttccat tgtcaccaag gatcttttta
    26401 gtgattgctt ttgcaatatc tacatcaaat ccttgtacag ttctgctctc aatatccatc
    26461 attccaaata atcgagtatc atacttgaca ccccagatga tttcattggt agatttgctt
    26521 cgctctaaaa tatcttcatt tgccaaccca tttcctttac atccggctag tgcaagaaaa
    26581 gcaatgccta aaaggaaaat caggcgtatt ttttttaacc tgcgcatctt tttcctccta
    26641 tcaatgattg ataactttac tgataaattg ctgtgctcgg acttcatttg gattttcgaa
    26701 aaagtctctc acatttctgc tgtcttccaa tacttctcca tcagccatga agataacacg
    26761 atccgccact tctttggcaa agcccatttc atgtgtcacg acaatcattg acataccgtc
    26821 atgagccaat tttttcataa cgtctaatac atcaccaatc atttccggat ccaaagcaga
    26881 agtaggttca tcaaacagca gcatctcagg attcatcgct aaacctctgg cgattgccac
    26941 ccgttgctgt tgtcccccgg ataacatgga aggataagaa tctttcttat ctaacatatt
    27001 gacagttttc aaaaatttct ccgcgttttt gactgcagtt gcctggtctt gcttcaacac
    27061 tttgattggt gctaatttga tgttttccag aacagtttta tttgggtaca aattgaaatg
    27121 ttggaaaacc atgccgatgt tttttcggac ttctgtcagt tttgtctttt tatcatgcaa
    27181 gtcagtatca ttaatcagca gcttacctga agagatcgtc tctaatccat tgatacagcg
    27241 aagcatcgtg ctctttcctg aaccagaagg accaatgaca acgacaactt ctcctttctc
    27301 gaattcgaga ttgatatttt ttaatgcgtg gaacttgcca taatatttat ccacgtgatc
    27361 aaatttaatc attgccatag aattacactc ccattattat ttagtaagat ttcttttaaa
    27421 gatgtataat aaaatacatt atatctgata gtttagtaat ttgtaaagtt tcttagaacg
    27481 tttattctcc cataaatatt tcttccattt ctaatctatt agttatttta tcctctttcc
    27541 ttgttttttc cttaggaact gttgtttctt ttcaggaaaa acggtaagat attaagtgct
    27601 cagacttaca aatcgtaaag aggtgtcttt tttgaaaaat attattttaa cgggagatcg
    27661 accaactggg aagctgcatt tagggcatta cgtcggttct ctaaaaaccc gagtggctat
    27721 gcaggcagat gaagacaacc aactgtttgt catgattgct gacatgcaag cactgacaga
    27781 taatgctaaa aatcctgaga aggtttcatc aaatgtcttg caagttgctt tagactattt
    27841 agccgtggga ttagatcctg caaaatctac tttatttatc caatcacaaa ttccggaatt
    27901 agctgaatta accatgtatt atttgaactt agtcagcgta ggacgcgttc ggcgcaatcc
    27961 gactgtcaaa acagaaatcg aacaaaaaaa attcggtgaa agcgtgccta caggattctt
    28021 tatctatcct gtttctcaag cagcagatat cactgcattc aaagcgaatc ttgtacctgt
    28081 tggtgaggat caaaaaccaa tgctagagca gacacaggaa atcgtacaaa gcttcaatca
    28141 tacatatggt gaagtcttgg tggaaccaaa aggcgtattc ccaccaaaag gaatgggtag
    28201 attacctgga atcgatggaa atggcaaaat gagtaaatcg ttaggaaacg gtatttatat
    28261 ctccgatcct gccgatgtct tacagaaaaa agtcatgagt atgtatactg atccaaacca
    28321 catccatgta caagatcctg gacaagtaga agggaatatg gtcttcacct acttggatgt
    28381 attcggaaca gataaagaag caattgaaga aatgaaagct cattaccgcc gcggcggact
    28441 tggtgatgta aagatcaaac gatacctcat tgatgtattg gaagctgaat ttgcaccgat
    28501 ccgtgcgcgc cgagaagaat tggaaaaaga tccttcagct gttatggaaa tcttacgtaa
    28561 aggtagtgaa gaagctgcta aagtagctgc acaaacactt tctgaagtaa aatcagcaat
    28621 gggaatcaat tacttccatt aattcattta ctctaaaaaa gcaggctgta aaggcctgtt
    28681 tttttatctc gtctctgtgc tattcctttt ttaaaatcaa aaaaagagat gtgacgaagt
    28741 tgtgtcacat ctttttttca aatgtatggt cttcaaaagc tacttgatcg ttacttacta
    28801 tattttcctt cttagcgaat acttgcctct aggttttcta ccaacgcttt ttcgactttt
    28861 tccattgctt tattgatttc ttcatctgtc aatgttgctt ctgggttgac gaatgtcagg
    28921 ctatacgcca tggatttatg tcctttttca atgttttctc cttgatagac atcaaataat
    28981 tggatatctg ttaaaaatct tccggcagca gaacggataa cttctgttaa ttcctgattt
    29041 gtcacagttt cttttacaag caaagcgatg tcccggctga ctgctgggaa ttttgtcact
    29101 gcttcgaaaa cgatcccttt ttgagcagct tccactatag cagataaatc aaactcagca
    29161 acatatgttt ctggaatatc ataacttttt gtaatcgttg gatgcacttg accgacaaaa
    29221 ccaataaatt tttcgccaag gtaaatcgca gcagttcttc caggatgcat ttccttcatt
    29281 tctgtcactg tttgataatg gacatcttca gtgatgccta gttgttcaaa taagttttct
    29341 aaaagaccct tgatggtgaa aaagtctaca ttttgagctt tcgtctgcca atctttttct
    29401 tcccaaatac cagaaatagc gattgctgca tgttttactt cttgcggcag atgtgtacgt
    29461 ggatcatttt cttggaagaa cacccgacca atttcatata aagcaatctc tgtatttttt
    29521 cgggcagtgt tataactgat atcatctaat agtccgctga tcaaattcat tcgtaataca
    29581 gaacgttctt cgctcattgg ccagtccaaa cgtgtaatat tactttcatt tataacaaac
    29641 tgtcttgatt tttcttctgt tgtcaatgca taactgattg cttcgctcaa tccgcttcct
    29701 tcaaagattg tacgaatttt acgagtagtt tcttgttctt ttgacaagct tccagcaacc
    29761 gtttctccac ttggaagtgt agatggcaac tggtcgtatc cataaatacg agcaacttct
    29821 tcgataatat ctgcttcgat ttggatatcc cagcgtcttg gtggtactac tacggaataa
    29881 acatactcct tttcttcata gctaaatcca agtgcttcaa aaatctcatt tacttcttta
    29941 acgacaagag atgttcctaa atattgattg atgcgttcaa gtgaaatctt cactgatacg
    30001 tcttctgctt tgatctctga gcctttgacc gcgccttgta gaacttcccc acccgcaaga
    30061 gaaacgatca ttgctgcagc aacctcactg gcttctccaa cagtcgcatg gttgattcct
    30121 ttttcaaaac gtgcagagga ttcactacgc aaattaaatt gttttgctgt acgacgaatc
    30181 gaaattggat caaataaagc agattctagt gcaactgttg ttgtttcatt cgtgatctct
    30241 gagtctaacc ctcccatgac accagctaaa gcaactggtt ctttgccgtt agtaatgacg
    30301 agattgtcag ttgtcaattc ccgagattct ccatctagtg ttactaatgt ttcattttct
    30361 tttgcacggc ggacaaagat ctcttttgat ttcaatttgt cgtagtcaaa tgcatgtagt
    30421 ggttgtccga ataaaagcaa aatatagttc gtcacatcta ctacattgtt gattggacga
    30481 atgccttcgt tcatcaaaag attttgcagc cattgaggac ttggctggat tcttactcct
    30541 tcaatgattc tgatttgata agcaggaact gcttctttat cttcaacttc cacttgaatt
    30601 ttatcgctag caggacgtga ggattctacc agcttttcgt catcgaatgt aggagtctga
    30661 cgataaattg ccccaacttc ataagctacg ccacgcattg acaatgcatc cgcacgattc
    30721 ggtgtgatag ataattcaat aatcgaatca tccatatcca aataaggaaa aactggatcg
    30781 ccatttacag cttcttgtgg catataatag ataccttcag cgtattcttt cggtataaca
    30841 ctatctgaat agccaatttc ttgtaatgag caaatcatgc catttgatac ttggccacgc
    30901 atttttcctt ttttgatttt tacattacca gcgatacgtg agttaggaag tgcaacaatc
    30961 actttgattc caaccttcac attaggcgct ccacaaacga tttgagacag ttcgtcttcg
    31021 ccaatatcga cttgacaaat agaaaggtga tcagaatctg gatgtggtac gcattccttg
    31081 acttcaccga caacgatttt tttcaagcct tcttctggaa ccgttactcc ctctacttcg
    31141 attcctgtca cagacatctt atccgctaat tcttttggtg ttacattcga taaatctaca
    31201 taacgattga gccatttata tgaaactaac attttcttac tcccccttga actgacttaa
    31261 gaaacgtaag tcattttgat agaaattacg gatatcattc actccatacc gcaacatagc
    31321 tacgcggtct ggtccaaggc cgaaagcaaa gcctgaatat tcttctggat cgattcctga
    31381 catcttcaac acattcgggt gtaccatgcc agctcctaaa atttcgatcc atccagtgta
    31441 tttacatacg ttacaaccgg caccaccaca tttgaaacag ctgacatcta cttctactga
    31501 tggttccgta aatgggaaat aacttggacg caaacgaatt tcacgatctt ccccaaacat
    31561 ttttttcatt acgacttcta atgttccttt aaggtcgccc attgtgatgt ttttatcaac
    31621 aactagccct tcaatttgat ggaactgatg actgtgggtc gcatcatctg tatctctgcg
    31681 gaagactttc cctggcgaga tcattcgtag agcaccctta gagaaatcat gtttttccat
    31741 tgtccgtgct tggactggtg aagtatgtgt ccgaatcaat atctcgtctg aaatatagaa
    31801 agtatcttgc atgtcccttg ctggatgatc ttttggcaga ttcatccgtt cgaaattgta
    31861 atgatcagat tctacttcat atccttctac gatctgatag cccataccca caaaaatatc
    31921 ttcaatttct tccatgattt gtgtcacgat atgacgtgta ccatgtttta cttttctacc
    31981 aggtagtgtc acgtctattg tttcttttgc caaagctgca tttaacgctt cttcttctaa
    32041 tacttgtttt tttcgctcga tctcttctgt caaaagatct cggatctcat ttgcgaaact
    32101 tccgactttt ggtcgctctt ctggacttag atctttcatc ccacgtaata cttctgtgat
    32161 cggtcctttt tttcctaacg tttcaacacg tatttgattt aattcattta aatcttgtgc
    32221 cgctgtgatt ttgacgagcg ttgcttcttt caagctctct aattgtgctt gtagagacat
    32281 gtgcttgttc ctcctttaaa ttccaaatac aaaacaaaaa gacctcattc ctgttaagga
    32341 acgaggtctt cgcgttacca tcctaatttg cggataaatg acttacaccg cactcttact
    32401 tcgttaacga caattgccgg tctgatttta tcagacgaac tcggaaagtg aacttcattt
    32461 ttcaaacaca ggatctgctt tcagtctgcg acagatctcc ctgaactggt ttagccaaac
    32521 tactcttttt cgtcatcgtt ctttacttat tcgtatggac tatagtttac aagatttttt
    32581 ttacaaaatc aaccgcattc ttcctctgtg atccattttt cgctccaaac ttgtatttga
    32641 cgcatcgctt tttgcaagtc tgctcctttt tcagtcaaga gatattctga acggctcttt
    32701 tcgctacagg caaagtttcg agtgactatt ccttcttttt ctaattcctt caagcgttcg
    32761 actaatactc gatcactgac catcgggatt tttgccgcaa gctcaacaaa gcgttgcgga
    32821 ccgttttcga gtagtacatc gataatcaat ccgttccatt tttttcctaa aatagagaat
    32881 gttttttcaa atttagggca taaaacgaat tctgtctgtg ttagctccat catactcacc
    32941 tcttcccaga gtatagcata atccttacaa aacataagtc aagtttgctc aattataatt
    33001 atttgttaat gtttataatt tgtttcactc gaagcaaaat taggaaaaca ttttctactg
    33061 gcttattcaa agcttctgac attgcttgtt ggtaaagtct tagctgtcct tgatattttt
    33121 ggacgattgc atctatttct gctggatcat ccggatgtaa aataaaatct gttttaaaat
    33181 catagatatt gagatgatct ttttcttcta ggtatccatc gacgattccg tggattaata
    33241 gttcatcttc ttgatttgga tagtcttgaa atacttcgtc agcaggaagc agcatggaaa
    33301 aaggttgttc tcgttttacg ttttctttgt tggcaatcag ctgttgacca agttctgttt
    33361 gaaagaacca tataatagaa gaaacatcta cttttttcgc gactttttcg tctactaacc
    33421 gtttccttac caattcctgt aatttttgat ggatactctc tgtagttggc atctctaatg
    33481 gcagtaattg taacaaagca tgcgtagcag ttccaacagc agctgctgac acttgccgat
    33541 ctttttgcaa aaattttggt tctgctagtt gttcttgcgt ataacgaaat tgacgggatg
    33601 ctgctttgtt ctgactgctt tccagagtca aacgtgattc ttgtgtatca tctggatctt
    33661 cgaataatcg tttgatttca gatacagatt gataacttgt ggtttgtgaa gaagcttgat
    33721 aaggatattc atatgccaga cgtttttgta acgaatctgc taataaagtt tcatcttctt
    33781 tcatctgctg atctaagtta accagttctt tttcagcaag caactgtctt tgttcaatga
    33841 tcgattgctg attcatccat gaaatagaaa actgtgcatt tgaatgttga agaagagaag
    33901 tcgaaatttc ttcctctaag tatttctgca tttcaggatg acggatcaat ccgtaaccaa
    33961 tccaattcat caagctgctt ctgcccttca aacgtagcgc aggatcaaaa actaactcct
    34021 catgatcagc tgcttcagac cacgtttgga tcatttgctc tttattttta taggaaccga
    34081 caatgaaaag cttttgttct gcccgagtca atcctacata caatttacgc atttcttccg
    34141 acaacaattt gttttgcttt gccaatttga tggcttgaaa cggtaacgta tcatataaca
    34201 ctcgtgtttc aggatccata tagcgaattc ctgctccaag tttttcttca aaagcatacc
    34261 gattgcgcaa gtcttgtaag ttgaactcct ttgtcatatc taacaaaaat acaactggga
    34321 attccaagcc tttacttgca tggatcgtca taacgcgaac agcattatct tctattgaaa
    34381 tgactggttc tgctaagtct ttatcttttt cttgcatttt ttcaatgaaa cgcacgaact
    34441 ggtataatcc tctgaaagaa ctttgctcgt aagctttggc acgatcaacc aatgcataaa
    34501 gattggcttg tctctgtgcc cctgctggca gaccgaccac atactctaga tatcccgtct
    34561 cataatagat atcccataac aagtcagtga tcgaagaacg gcgagcaagt tctcgccaat
    34621 gctctagttg cttgccaaaa tgttccagct tagctgctaa ttcatcttcg tttgatgctt
    34681 gataagcaag cacagcatca tagtaagtat gtgcacggtt agctaatcga atgctggcta
    34741 attctggttc aatcagaccc acgatcggtg agcgcaatac agccgcaagc ggaatatctt
    34801 gatagggatt atcgattaat tgtagcagcg agatcatcgt gcgaatttct gtcgcttgaa
    34861 aatagttttg agcatcattc atctctaatg gaatatccaa tgttttgaaa atctctaaaa
    34921 tcgttaagtt gttcttcttt gtaggtgtca agagaacaat gtctttgtac tctatcggac
    34981 gacttttttt tgatttttta tcataaatca taaaggagga atcaattaat tgacgaattt
    35041 ttagtcctgt cataaaaagt tcgccttctg ttttgtcttc cagtatatca tccgtcggaa
    35101 tctcaatctc tgattcttcc tgttcttttt catagatcat gatttccggc tcaaactgtt
    35161 cattctctgg aaagtctgaa aatccttgga tcagtttggc tgcttcgtca taattgattt
    35221 gacccactgc tggatccatt agttgttcaa aaataagatt cgtaaaagaa aggacttctt
    35281 ttctagagcg gaagttctca gccaaaacga ttcgacgtcc gccttctttc tttgagaaat
    35341 tctcgtattt cccgataaat aaactaggat ctgctaaacg gaaagaatag atggattgtt
    35401 tgacatcccc aaccatgaac atatttcctt ttgtatcatc gggttctctt agccagtata
    35461 aaatggcttc ttgtaattgg ttcacgtctt gatattcatc taccattact tctttgaatt
    35521 tttttcgata atgttttgaa gcttcacttg gcagccatac atctttcgtt ttttctgtga
    35581 gaatctgcaa cgctaaatgt tccagatcat tgaaatccag cacacctttt tcccgtttac
    35641 gcatactgaa accgtccatg aagctttgcg tgacttttgt catttcttcg actaacggta
    35701 gtgctttgtc cgttaattct tccatttggc ttggggaaac aggaaaataa cttttactta
    35761 tctgctgaat cagttttttt gctttatccc tcatgccctt gacttcattg gaaatttctt
    35821 tcaattctgc tttccgactg ctcttaaaag ttgaaaaagt tagttgttcc aaaccagcat
    35881 aagcttcttc taaccgatct tgcgagaacg cttcatagat attcttgatc tgctgttgtt
    35941 ctccagctac ttgctcatgc attttttcta atccttcacc ttgtgctaac tgagtcatct
    36001 gttcatataa ctgtacacat tggtatatat ctgccaaaac taaaggacgg atttgttttt
    36061 gatataatcg agatttcgct agcccctcag gcaaacgata attatcgctt aactgttcta
    36121 gccatttttg ggggtcaggg ttggcacggg caaactcata aagagaaaac accagattcg
    36181 tcaagccgtc atctgaacga tcattagaaa aattcattgt taattggaaa aatcgttcat
    36241 cattttctgc ataaagtgct tctctcagct cgtcccacac atcctccttc atcaagatcg
    36301 tttctgtttc atctgttaac atgcgaaaga ctggatcaat atcaattaag taataataac
    36361 gtcgaataac tgtcaggcaa aaagcatgta aggttgagat attcgctgtg ggcaataaaa
    36421 ctaactgctt agtaaaatgc tgtctacgta cagggtcact ttcgctattg acggattctt
    36481 gtaatgcctc ttgaattctt tctttcattt ctcttgcggc agcttcagta aatgtcacaa
    36541 tcaataattc atcgatatca aaacccattt ttagtttttc aatcactctt cgaacaagca
    36601 ctgtagtttt acctgatccg gcagacgcag agactaatag attatctcct tgatcaaaaa
    36661 tcgcttgcca ctgatcatct gtgaatcgtt cattttgcgg ttttaaagga atttgattca
    36721 ctcttcttca ctccttttca atattctacg cagtgcttct tccttatcta ttttctccag
    36781 acggtggtaa ttattttctt tcagcatcac atcaaacgta cagatgcttc tgaatggaca
    36841 aaattcgcag gcaatccgct gtttatcttt ataagctgga tttagtttga tttctccgga
    36901 agtaatcgca tctccagcta accgcatatt ttcccgatta tgcgccatga atagttgcag
    36961 ttcttcttcc gtgaaaaatt tgtctttact gaaactacct ttttggtatt catctttcgc
    37021 attttttttc actggataga tcagtgattg ttcttttgct tccagtgaat gatctagtac
    37081 ttctaaaaga gcgggatcat cgacaaaaac gccatcataa ctaaattttt tcaatgtatt
    37141 cttctctaca tcatctgtct ccgtcaatac aggattatga acatgtaaat aatatgatcc
    37201 tgctggttta acagccgcct ttccagtcaa acgtaccgca tccatcaatg ctacgtccag
    37261 atacgtcaat aattgcatag ccatgccata ataagcttct gtgacatcga atgaacgtcc
    37321 gctagatttg taatcaacga cgcttagcca agtatcttct tgttcagaag ctacatcgat
    37381 tcgatcgatt ttccctcgaa catggagttt tccaccatta ctcaacggta attccagacc
    37441 tgtgatacct tttgctccag caatctgacc aaatagaatc tctgtctgaa gaggatgcat
    37501 gcctgtattt ttgctctgtt tttgcaaagc ccatgtcact ttttgaatcg tctgtcctaa
    37561 ctggtagcgg atatagttca ttcttgcaga actatccaat atctcaaacc gaagttctcc
    37621 gaatacttcc tgcagcactt tttcagtaaa gtctctacgc tgcgcatcgg acatattcac
    37681 taaggataat tggtttgaaa acagtagctt gaagaaacga tccaatgatt catgataaaa
    37741 atcaccagtt gctgctggag ttagaccata aacagttcgt tctttcaatt tcaaaccaaa
    37801 ttgcatgaag tatttgtatt cacaattata aaaattctcc atacgtgaaa ttgaagtata
    37861 aatctctttt ccataaagct cttccgccat tttttctggc atcgaaacag gaacatttaa
    37921 atgttcctga ctttcaaaaa tctgtaaagc aaaatttcgc catgacgaat tcagtactaa
    37981 ttctttgagc ttttgccagt gctttggtac aggttttttt tcatctaaag ctaatcgata
    38041 aatcctattg actgtattga ttccgcttct gtaagtccct acataacaat tagggtcgct
    38101 ttcgatcgtc aaatgctctt ttctctcgac gggaacagat aaatattctg tgattctacg
    38161 caaataagga gacatcttca gcgaaccatc tgtgtcatag ctttgtgcat aactaagata
    38221 taatcgatct gttccggaaa gaaaaacaag ataggcttgg aaaggctcaa aagagatact
    38281 ttcctttgat gggtcgaata aaaactgtcc atctggcaag gcctgattta atacttctcg
    38341 ttcttcactg gacaacaatc cttttgtctc ttttcggtct ggaaacactt gatcattcaa
    38401 ccctaatgca aaagtgacgg cagcttgatt tggtcgaact aattccaaac gattgattcg
    38461 cacttggtcg attgcggtag ggattttacc ataacttaga ttttctagac cacttgtaat
    38521 gatttcttgg aacagtgacc agtcaaaagc cgattcacca taaattacta catattcatc
    38581 caacagatca atcagcgctc cccatgtctg ctcatggttt cttgccgctt ctaagtttcc
    38641 tctgtctact tcctgattac gccaaaacaa taattgttgc tgtacgccac tttggatcaa
    38701 aaattgataa aaaacatttg cggcctcttg tcctgttttg cttttcttta tttttttcaa
    38761 aaatactggt acagctttct gaaataatcg tctaatcgta tttgactgtt cttccaaata
    38821 ctgtacgtct tcaatctgtt ctgcttcaaa atcatacgcc acaaactgcc agtctttttc
    38881 acgagtccaa taagttcctt gataattgta agcaagtgct acattttcag tgatgtccag
    38941 ttttttcctg aattcatctc gctcttgttt ccattcatca agttcggttt ctgcttccgt
    39001 cgacagaaat aattcagttt tgaaaaaacg cataatatca cttagccgat aagaatagcg
    39061 gtcaagagcg aacagactgt tgatccattc gatcagcgga tgattttcca tcatttgttc
    39121 ttcatcgata taaaaaggaa ttgccatttc ttgaaagatc ggccgaagga tatttccata
    39181 taaagacata ttttttgtca gcacttggat atcacgataa cggtagtttt cttcactgac
    39241 tagtcgtctg atttcaacag ctaattgtcg gacttcttca gttggatttt cagcttccca
    39301 caaatggaga tgctcttgtc cccctatttt gtgtactgcc gctttctttt ggctagatgt
    39361 ctcttcccac attgtttgca gcagttgaag ctctgtcgga cgagtctgct ctggtgcaaa
    39421 tcggtccact aatataggga ctttccgttc tcttgcactt tgaaaaagac ggaaataaag
    39481 ctttccagtc tcatgaaaga gcgtaagtac ttctggaaga tccgctgtat aaggacgatc
    39541 cagcaataaa tcgacaacca attgcccctt ttccatcatt gcctgcagta attgatactc
    39601 ttgaccattg attcgagaaa aaccactgac aataaatttg acgttgttga aatcttgtgt
    39661 ctgcatataa tttgctagta tagatagtgc atcttcattt gttagtgcac gttgagtcaa
    39721 ttcgctgtca taagctgaaa aaatcagctt caagtctttc attttaagtt gctggtcttc
    39781 tgcattaggt gaatcaccaa ataaaagcat caggtcttct ggttgaatat ttcctgtacg
    39841 caattcactg tagagttctt gtaattgacg aataaaccct cttttattga tttctccgcg
    39901 aaagattgtt aattcttcct catttttttc taaaatctgt cgcaagatca ttgcagatcc
    39961 tgattctgat aattcatttc ctgtaagaag agttgtctgt tgcagcaaat accaagccag
    40021 acgataaaaa ctaaatactt gaacgtttgt tgtgctgaaa gttttttttc cgcttcttct
    40081 tcgcatctcc gctaaaattt cttgttcctg ttcgaatttg ctgtagttgg gaacaaggaa
    40141 aaatacttgg ttacttgcat cctggtcgag ccaagcggat gcttcgtcga tcaagacttg
    40201 acggtgatct tttttcccgt ttccaagaat aaattgtaaa gacatgcttt tcctccttca
    40261 acacatgata cggtgctcct ttattatatc aaaaaatact gaacatttgt tctatattct
    40321 tcaaattata tccttttaag gttctgatat ttctactttt ttaagtatac g
//
LOCUS       DARPZF010000021        37751 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.022, whole genome shotgun sequence.
ACCESSION   DARPZF010000021 DARPZF010000000
VERSION     DARPZF010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37751
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.022"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(66..686)
                     /locus_tag="SLE65_001415"
     CDS             complement(66..686)
                     /locus_tag="SLE65_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HEI8448718.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(878..1174)
                     /locus_tag="SLE65_001416"
     CDS             complement(878..1174)
                     /locus_tag="SLE65_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEI8448719.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            1378..2028
                     /locus_tag="SLE65_001417"
     CDS             1378..2028
                     /locus_tag="SLE65_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HEI8448720.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            2044..3771
                     /locus_tag="SLE65_001418"
     CDS             2044..3771
                     /locus_tag="SLE65_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8448721.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            3768..5660
                     /locus_tag="SLE65_001419"
     CDS             3768..5660
                     /locus_tag="SLE65_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8448722.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            6364..7233
                     /locus_tag="SLE65_001420"
     CDS             6364..7233
                     /locus_tag="SLE65_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HEI8448723.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            7442..8467
                     /locus_tag="SLE65_001421"
     CDS             7442..8467
                     /locus_tag="SLE65_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEI8448724.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            8506..9456
                     /gene="manA"
                     /locus_tag="SLE65_001422"
     CDS             8506..9456
                     /gene="manA"
                     /locus_tag="SLE65_001422"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEI8448725.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            9550..11252
                     /locus_tag="SLE65_001423"
                     /pseudo
     CDS             9550..11252
                     /locus_tag="SLE65_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
     gene            11254..13287
                     /locus_tag="SLE65_001424"
     CDS             11254..13287
                     /locus_tag="SLE65_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEI8448726.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            13298..13738
                     /locus_tag="SLE65_001425"
     CDS             13298..13738
                     /locus_tag="SLE65_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEI8448727.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(13938..15065)
                     /locus_tag="SLE65_001426"
     CDS             complement(13938..15065)
                     /locus_tag="SLE65_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8448728.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(15068..15745)
                     /locus_tag="SLE65_001427"
     CDS             complement(15068..15745)
                     /locus_tag="SLE65_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8448729.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            16009..17775
                     /locus_tag="SLE65_001428"
     CDS             16009..17775
                     /locus_tag="SLE65_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEI8448730.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            17790..18227
                     /locus_tag="SLE65_001429"
     CDS             17790..18227
                     /locus_tag="SLE65_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEI8448731.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            18240..19391
                     /locus_tag="SLE65_001430"
     CDS             18240..19391
                     /locus_tag="SLE65_001430"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEI8448732.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(19453..20151)
                     /locus_tag="SLE65_001431"
     CDS             complement(19453..20151)
                     /locus_tag="SLE65_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEI8448733.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(20144..21496)
                     /locus_tag="SLE65_001432"
     CDS             complement(20144..21496)
                     /locus_tag="SLE65_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEI8448734.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(21719..23119)
                     /locus_tag="SLE65_001433"
     CDS             complement(21719..23119)
                     /locus_tag="SLE65_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEI8448735.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            23280..24017
                     /locus_tag="SLE65_001434"
     CDS             23280..24017
                     /locus_tag="SLE65_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEI8448736.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            24142..24621
                     /locus_tag="SLE65_001435"
     CDS             24142..24621
                     /locus_tag="SLE65_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HEI8448737.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            24618..25385
                     /locus_tag="SLE65_001436"
     CDS             24618..25385
                     /locus_tag="SLE65_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448738.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            25615..26184
                     /gene="lepB"
                     /locus_tag="SLE65_001437"
     CDS             25615..26184
                     /gene="lepB"
                     /locus_tag="SLE65_001437"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEI8448739.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(26288..26890)
                     /locus_tag="SLE65_001438"
     CDS             complement(26288..26890)
                     /locus_tag="SLE65_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEI8448740.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            26996..27465
                     /locus_tag="SLE65_001439"
                     /pseudo
     CDS             26996..27465
                     /locus_tag="SLE65_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            27571..28155
                     /locus_tag="SLE65_001440"
     CDS             27571..28155
                     /locus_tag="SLE65_001440"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEI8448741.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            28158..29231
                     /gene="prfA"
                     /locus_tag="SLE65_001441"
     CDS             28158..29231
                     /gene="prfA"
                     /locus_tag="SLE65_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEI8448742.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            29224..30063
                     /gene="prmC"
                     /locus_tag="SLE65_001442"
     CDS             29224..30063
                     /gene="prmC"
                     /locus_tag="SLE65_001442"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEI8448743.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            30056..30235
                     /locus_tag="SLE65_001443"
     CDS             30056..30235
                     /locus_tag="SLE65_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448744.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            30257..31282
                     /locus_tag="SLE65_001444"
     CDS             30257..31282
                     /locus_tag="SLE65_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEI8448745.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            31457..32701
                     /locus_tag="SLE65_001445"
     CDS             31457..32701
                     /locus_tag="SLE65_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEI8448746.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            32854..33801
                     /locus_tag="SLE65_001446"
     CDS             32854..33801
                     /locus_tag="SLE65_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEI8448747.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            33935..34564
                     /gene="upp"
                     /locus_tag="SLE65_001447"
     CDS             33935..34564
                     /gene="upp"
                     /locus_tag="SLE65_001447"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEI8448748.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(34703..34945)
                     /locus_tag="SLE65_001448"
     CDS             complement(34703..34945)
                     /locus_tag="SLE65_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448749.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            35066..35138
                     /locus_tag="SLE65_001449"
     tRNA            35066..35138
                     /locus_tag="SLE65_001449"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35099..35101,aa:Thr,seq:cgt)
     gene            complement(35257..35895)
                     /locus_tag="SLE65_001450"
     CDS             complement(35257..35895)
                     /locus_tag="SLE65_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEI8448750.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(36018..36650)
                     /locus_tag="SLE65_001451"
     CDS             complement(36018..36650)
                     /locus_tag="SLE65_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HEI8448751.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            37001..37300
                     /locus_tag="SLE65_001452"
     CDS             37001..37300
                     /locus_tag="SLE65_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEI8448752.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT        12765 a         6614 c         7602 g        10770 t
ORIGIN      
        1 caaggcacaa atgctgcttt gaagattttt tcctctgtct cttttgtatg catttatctc
       61 aatttttaaa atgatttacc taaagcagca gctttatcta atgcattttg catcaactca
      121 tctgcacggt cagggtcata atcgattcct tcgatgaata gctgatctac ttgatcgatg
      181 cctacaaagt ttaaaatacc ttttacatat tgagaggcaa agtcttgtcc gttgtataca
      241 ccgccattag attggatgtg cagtgctttt ttacctgtca ctaatccttc tggcccgttt
      301 tctgtatagc ggaacgtttt tccagctaca ttgacggtat cgaaccaagc ttttaatttt
      361 gttgggatat ttagattcca taaggcgttt gcgataacga ttttatcagc agcaaggaac
      421 tgatcagtca attcattgaa acgagcaatt ttttgttgtt gactttctga taaggaagtg
      481 aattctgcac cagcacgtaa tgcttcccaa cctgataata attcttcatc gatttccgga
      541 atatcatcgc gataaagttc caaaacagtc acttcatcat ctggatgatt ttctttataa
      601 cttgttaaaa aagacgtcaa tgccttaact gtgcgcgatt cttctgcagt taggggatga
      661 cctttgacta ctaaaacaga tgccatatgc ttaccttctc cttttattgc tatgattgtt
      721 ataactatga ctaacaaaat cagtttactc gaaaaagaaa aggctatcaa gtcatattga
      781 taaggttgaa gaataaataa ctaaaaaaag acagggtata aaagaggctg tgacacgatt
      841 ttttgtcaca gcctcttttg aatctaacaa gcaatattca agcaacactc gactgaagag
      901 cttccatccc accaatgata taaacagcac gaaaaccatt agcagtaagt tgatcggcta
      961 atgcttctga tcgcctgcct gtatagctta gaatataata aagtttcttt ggatctagat
     1021 tttttaattg tcttggcaag atagcagcgg ggatagaaag cgagtggctt aagtggtttt
     1081 ttgtgtaatc taaggtattt cttgtatcta aaacgatgct gtcagcatcg agaggcaatt
     1141 tattgaagtc ttggacacta attgattggg ccatttatct catcctttgt ttagtatgtg
     1201 gctattttaa tgggcaactc tcattaattc aaatggaagg attcctctta tcactttttt
     1261 aatgtatcgg atgataatga aaaaaactat gcaaatgtct tgcaaaacag gtaggaggtg
     1321 ttataatgac atagcgtcat atgacaatgt gtcatcttga aagaaaggag aatccatatg
     1381 ccgacacaga catttttcca tttgcctaaa gaaaaacaaa aaagactaat cgaggctgcg
     1441 agaatcgagt tttctagagt acccttaaaa gaagcttcga ttgctaatat cgtcaaatta
     1501 gcggatatcc ctagaggcag tttctatcag tattttgaag ataaagagga tctttatttt
     1561 tattactttg agacaatgag acgtgacagc tctaaagata tgttacaact aatgaaagaa
     1621 tccgatggtg atctattcaa aggattcgaa tcctattttt ctaaaatgat ttatgagatt
     1681 ttggaaggcg agaatgcttc tttttatcgt aacttgttta tgaacatgga ttaccgtgcc
     1741 tcaagaaaag tcgctcctca tacgagtcgc caaaaaacgc ctcacgatcc acataaagaa
     1801 cacaaacaag atgcaaaaga gttgcttgaa ttgatcgatc ggacgaagct gaaagtaaaa
     1861 aatgatcatg aattggaatt actgatccaa ttagtgatga atactgtatt tacaacaatt
     1921 gcgcattcgt atcgcttatt ttcaacatct gaagattact cagtagagca agcaatcagt
     1981 gaattcaatt tgaaactttc ttggctgaaa aacggagtat ataaatagaa agaagggaac
     2041 tagatgctaa aaatcgtaaa acggatctcc ttgacttcag caattgcagc tgcagttttc
     2101 atggtgatcc aagtactggc agatttatat ttgccgacac ttacctccaa tattattgat
     2161 aaaggggtag cgcaaggaga tgtcgattat atttggcata caggttttgt gatgatcggc
     2221 ttttctttga tcagtatctt agctgctatc gcaaatacat tttttgctac tcgtgaatca
     2281 cagaaactgg gtaagcaatt gcgtacggat gtctataaaa aatcagagag tctgacaaaa
     2341 gatgcgtttg ataaatatgg aacggcctct ttgatcacaa gaacgaccaa tgatgtgact
     2401 caaatccaaa tggttacaca aatgttttta cgtatgatga tcaatgcacc aatcacgttg
     2461 attggcgcga gcatacttgc ttatcaaaaa gatcatcagt tgacaaaaat cttcttagtt
     2521 gtcatcccag taatgattat tttgatcggc ggaatcatgt actttgctgt tccattattc
     2581 aaaagtatgc aaaagaaaac tgaccgttta aacctggtat ttcgagaagg attgacaggg
     2641 gtcagagtga ttcgagcatt cgataagaca cgctttgaag aaaatcgttt tgatttagcg
     2701 aataaagatt atacaaatac ggcaatcaaa gttaatacga tcgtcgcatt gatgatgcca
     2761 atgatgacat tgatcatgag cggtacaaac gtagcaatca cttggtttgg tggacactac
     2821 atagcagata tgactttgga agtcggtaat ctgattgcat ttatgactta tgcgatgcag
     2881 atcttgatca gctttatgat gctttccgct atttttatca tggtgcctcg tgcacaagct
     2941 tcagctgacc gtattaatga agtgttggat gaaaaaatcg gtatccatga ccctgaaaat
     3001 cctaaaacag tttcttttgc tggaaaaaac gcaacattgg ccttcaatca tgtcaattat
     3061 cgatatcatg gagcagaaaa acttgcattg gaagatattg atttccaagc caagtcgggc
     3121 gagatcgtcg caatcatagg ggggactggt tcaggtaaaa cgaccttagt caatttgatc
     3181 cctcgattat atgacatcga atctggttcg atccaaataa atggaacgga cattagtgac
     3241 atgactcaat ataatttgcg agaattaatg ggctttgttc ctcaaaaagc agttctgttc
     3301 tctggaacga tccgagacaa tatgcagtat ggtaagccgg atgcaacaga tgaaatgatt
     3361 tggaaagcat tagaaatcgc acaagctaaa gattttgttt cagagatgga agatggctta
     3421 gatagccatg tggaacaagg aggaggaaac ttctctggtg gacaaagaca gcgtctggca
     3481 attgcacggg cattagtcaa aacagcagat atctatgtgt ttgatgattc cttctcagcg
     3541 ttggatttca aaacggatgc caatcttcgc caagcattga aaacgaatat gaaagaaagt
     3601 atcaccgttt tagttgctca acgagtaagt acagtaatgg atgcagatat gatccttgtg
     3661 ctagatgaag gaaaactggt tggcaaagga acacatgaag aactattagc aacaaacgaa
     3721 acttatcaag aaatcgttca ttcacaacta agagaggagg acttagcatg agtaaaacaa
     3781 acacacgtcc ctctcatgga ccagcaggcg gtccaggaca tggtggacct ggcagaaatc
     3841 tcggtgtaaa aggtgaaaag cctaaaaatt tctggggaac ggtacgccga ttgtttggct
     3901 atatgtctaa acgtatggtt gcgatcatcg ctgtatttgt actagcaata gcagccgtga
     3961 tcttccaaat ccaaacacca aaggtcttgg ggaaagcaac cacagaaata ttcaaaggtg
     4021 taatggctgg cgctcaacag atgcaacaag gccaacaagt aacaaaattt ccgatagact
     4081 ttgataaaat cgcgcagatc attgcgacag taatcgtgat gtatttgatt tctgctgtat
     4141 tcaacttttt acagcaattt attatgacac gtgtttccca acgaacagtt tatgaattac
     4201 gtcatgattt ggaagccaaa atgaatcgtg taccgatttc ctattatgat acacatacaa
     4261 atggggatat catgtctcga gcaatcaatg atatggataa catcgcaagc acgctgcagc
     4321 aaaatttgac tcaatttgta actagtgcag tcacattgat tggggtcatc gtgatgatgc
     4381 tttcaatcag ctggcaattg acgttagtcg cgttattgat gatcccttta agcttgatca
     4441 tcgtgatgat cgtagcgccg aaatcacaag tgtttttcgc agatcagcaa aaaagtttag
     4501 gtttattgaa taaccaagta gaagaaacat atggtggtca taccattgtt aaaacattca
     4561 atcatactga aaaagaccag gaagtatttg aaaaagaaaa tcagaatctg tatgccgctg
     4621 gttggaaagc tcaatttatt tcggcaatca tcatgccgtt gatgaatttc gttaaaaatc
     4681 taggctatgt gttcgtcgct gtactaggcg gagtaaaagt tgcaaatggg aacatgacat
     4741 taggggatgt tcaagcgttc ttgcaatata caacacagtt ctctcaacca atcactcaac
     4801 ttgcaagttt gatgaacact atccaatcaa cagttgcttc agccgaacgg gtatttgaag
     4861 tgttggatga agaagagatg tccaatgaaa aatctggcct tccagaagaa aaagatacac
     4921 catacaaagt tcgttttgaa aatgttcaat tcggctacac accagataac ttgctaatga
     4981 ctgattttaa cttggatgtc aaacctggtg agatggtcgc tattgtaggt ccgactggtg
     5041 cagggaagac gacactgatc aaccttcttg aacggttcta cgatgtttct ggaggtagta
     5101 ttcgttacga tggtgtagat acccgtgatc tttcacgtga tgaattgcgc gcacagtttt
     5161 caatggtact gcaagatact tggctgttta caggaagtat ctatgacaat atcaaatatg
     5221 ggaacgacga tgcaacagac gaacaaatca ttgaggctgc taaagctgct cacgtagacg
     5281 attttgttcg taaattgcca gaaggatata acactgtatt aaacgaggat gcaagcaata
     5341 tttcgcaagg gcagcgtcag ctaatcacaa ttgcgcgggc attcttagca aatccagatg
     5401 tcctgatcct tgatgaagca acatctagtg tagatacacg aacagaaata ctgattcaaa
     5461 aagcgatgaa ccgcctattg gaaaaccgga caagtttcgt tgttgctcac cgcttgtcta
     5521 caatacgcga tgcagacaac attattgtga tgaatcatgg ttcgatcgta gaaacaggaa
     5581 accacgatac attgatggaa aaagacggat tctatgcaga tctttataac agtcagtttt
     5641 ctgaagaaga agcttcatag aatagtacaa atttattatt ttttttaggg gctgtgacaa
     5701 aagtcgtgtc acagtccctt tttccgaata aacggtgttc aatcagctgt ccttcggtat
     5761 tagctcaaaa aacggcaaaa tatgagaagc tatttttccg ttttgtatct ctaatactca
     5821 ggtcaaaccg ctgattttac aacctcttcc ttaaacggtg ttctcctgcc aactcctcgg
     5881 tcacaagtca caatagtcaa caaacctgag aagctgtttt ttgaaattgc tccttgtgac
     5941 tcggagttaa acggcaggct cacaacctct tggtaaacgg tgttcaaaag ccagtttctc
     6001 ggtattaagc caaatttatg caaaaatgta gaaagccatt ttcacaaaat ttttcttact
     6061 actcgaaact aagcgacttt ttcacaacct cttccttaaa cggtgttcaa aagcttgcat
     6121 ctgcggtaat aagcccaacc aaacgaaaaa taggaggagc tatttttgtt tggctgttct
     6181 tattacttga tgcagaacag ctttttcaca acctcttttt ataagagttt ttactcatta
     6241 atttacaaaa aacaagcaaa atgcgaattt tctcacattt tttttaacaa aatcaaagtt
     6301 attgcttgaa agaagaagaa tccatcgtta aaataaagct tgacgtagag gggagcaaga
     6361 aatatgaaag attttcaatt gggggctgcc acctatttaa aaagtgtagc cattcgggtg
     6421 aaagaccgag ataaaatgat tgatttttac aagaacgttg ttggctttga tttgaaaaga
     6481 gaagaaaacg aattagccat tttaggaaca gaagaagctg gaagtgaaat gttgctgctg
     6541 gaagaaagtc ctagagcgaa tgatcacatg ggggtgatca aaaagctgaa ccgtttttca
     6601 ttgattatcc ctagcacaga agaaatggca gatatccttt gtcgtatccg taaaatgaat
     6661 tatccaatca aagaagcttt agaagatcat ggacgtatgg ggattttgct cgtagaccca
     6721 gaagagaatg aattggaaat ttaccatgaa gagaataaga acgaccaaag agaaattcca
     6781 gaaacaatgg atcaagaagc attattaaga aaatctgaag aaaaattcag taaactatca
     6841 acaggttctt attttgaaaa aatccattta aatgttacta acttaacaaa agaacgccaa
     6901 tttcttaatc atgtacttgg tttgaaggta cataatgaag aagagggcat ccatgtattg
     6961 aatgaaggag atttccatgt tggtttgaca gaagctagcg gaggcgcaat tgatttgcct
     7021 acagatgaag tgattggact tgattttctg aaattcatga tcgatactga aagcatggaa
     7081 ggactgattg ctcacttgca gcaactatca gttgatttct tcttagacaa aaagcacaca
     7141 gtactcacaa tctatgatgc tataggaatc gaatggtggt tcgtcagtga gccaaaagaa
     7201 aagaataaaa ctgacattcg atgcgacgct taactttttc tttcttaacg attgtcgcat
     7261 gtctcgtcat tttatgaacg gtcatactat cgcttattct agagatagaa agagaaaata
     7321 gtataccggg ggaaactgcg cggtttttcg cgcagttttt ttgtgtaaaa aaggttgatt
     7381 cctcatagat taagctttaa gcttggactg taagaatctg atagaaaagc aggagaaaaa
     7441 gatgtatcca cacacgaaac agcttatttt gaaaaagatg gaagaaggat tttatccagg
     7501 tgtagcagtc gccttcataa aagaaaatca agtagaaaca tttacagccg gctttgccca
     7561 agtcgttcct gaaaagcagc tgatgacaga agatctgttg tttgatgcag cctcactgac
     7621 gaaagtcgtt gcaaccactt cattagtttt acgtctatta gaagatggaa agatagaact
     7681 cgatcaaccg cttcataaat atcttcctga atttgaaaat cagacaatca ctttgcgtca
     7741 tttactgaca catacttctg atatcaaaac atggatacca aacagagata agctatctca
     7801 ggaagaattg atcgccgctt atttgaagct agaaccaggt gagcaactag gaaaagaagt
     7861 aaaatataca gatgccggta cgattcttct tgggttgatg ctagaggaaa tttaccaaga
     7921 aactgcagtg gaaatctttc aagaacaagt attggaacca ttaggaatga tgaacagctt
     7981 atttcttcct tttccttcca aaaaaatcgt tcccacagaa caactgcctt cgggtgaggt
     8041 tttgcgtgga caaactcatg atccgaaagc aagagttttg gctgaacatg caggtaacgc
     8101 gggtctcttt attgatttga aagacagcat tacttttgtc caaatgtatt tgaacaaggg
     8161 aaaaatccgt aatggtcgtt ttttagaaga agagacgatt gattctttac tgcaagatca
     8221 aacaccgaaa aaaaatggct atcgttcttt aggatgggac ttaaaaaagg atgtagaaga
     8281 cggtcatgcg attctttttc atactggtta tacaggtacg tttttcttga ttgatataaa
     8341 aacacaagaa gcgttgatat ttttgtcaaa tcgcgtacat cctgtcgatc atcgtgcgga
     8401 gtatctcata tgtcgagatg aaattgttga aaactttttg aaagagaaag cggtattacc
     8461 gaaataatgc tataatagct atgaaaaatg agaggagttt gaattatgca ggaacctatg
     8521 tttttaaaac cagtttttca agaaaaaatt tggggaggaa gtcgtttacg ttcagtcttt
     8581 ggttttgata tccctaacga taaaatcgga gaagattggg cgatcagtgc gcatcctcat
     8641 ggtgtcagtg tagtagaaaa tggcgaattc aaagggaaaa gattagatga actatggtca
     8701 gaacacaagg aattgtttgg ccatccttca gaaccagtgt ttccattatt gatcaagatc
     8761 ttagacgcag aagatgatct atctgtacaa gtacatccag atgatgccta tgggatgaaa
     8821 catgaaggtg aattaggaaa aactgaatgc tggtatatca tcgatgctga acctggtgca
     8881 gaaatcatct atggtcatca tgcaaagaca agagaagaac tagctgagat gatcaaagat
     8941 gggcgctggg atgacctttt gaagaaagta ccagttaaaa aaggtgattt cttttatgta
     9001 ccaagcggaa cgatccatgc tattggtaaa ggaatcatga ttttagaaac acagcaaagt
     9061 tctgacacga cttaccgcgt gtatgactac gacagaaaag atgcgcaagg acaaacaaga
     9121 gagctgcata tccaacaatc gatcgatgta acaactgtcc ctgcgaaaac accagaatta
     9181 caaatcaaag aagtccgaaa agggaattca tcgatcgtca cttatttaga aactgagttt
     9241 ttcaatgtat atgagtggga tattaaagga atcacatctt tcaaaaaaca agccccttat
     9301 acattgatga cggtaatcga aggagcagga gaccttgtcg ttgacggaaa aacatatcca
     9361 ttagaaaaag gaacaagctg tattattcca aatggcgttt ctgagtgggc ggtccaaggt
     9421 gaactagcaa tcattgcgtc tgaaccaggc aaatagttcc cagatagctg aaagcagcag
     9481 acggtttttc gtttgctgct ttttctacat aaaatccgtc catcaataaa tagaagtctg
     9541 gtgaaaaaga tggaatacaa atggaaagca aacaacagca gtcgcgtgtc tatgaaacaa
     9601 ctgagaaaag ctggacatca cctaaatgaa atgatcatgc caaatctaag tctgtttatc
     9661 gcttggggaa tcttgtcatt agcaacaaaa ggtgtgtctg gcgatttgca caccacatta
     9721 gaagaggtat gccattggat gatccagctg cttttaccca tcttgatcag ttattcaggc
     9781 gggaaatcgg tagggggaca aaaaggggca gtcgccggtg caattgcttc tttagggttg
     9841 atcgctcgtt ccaatgctcc acaaatcgta ggagcgatga ttatcgggcc gcttgccggc
     9901 atcgtatatg aacaatttgt ttctagattc catgtgaaat tcaaggctgg atatgaaatg
     9961 cttgtcagca acctactagt aggactgact ggtagcgtta tttgtataat tggaatcgtt
    10021 tttattgaac cagttttaaa tagtgttcac ttgttgctcg cctccgttgt gtcttggcta
    10081 gtcacaatga atctgttacc acttgtcagt ctgatcttag aacctctaaa agtactattt
    10141 ttcaataatg caatcaatca tggtgtattg acacctttag gaatcgaatt ctcacaaaca
    10201 gtcgggtact cttccttatt tttgatggag gcaaatcctg gacctggttt agggatctta
    10261 ctttctatcc tttgttttgc agaaaaacag gaaaaagtaa atgcgagtgg agcattgatg
    10321 atccatgcga ttggcgggat tcacgaaatc tattttccat ttgtcttgct gcgaccgtat
    10381 ctatttttag ctgtaatggc tggtggggca agcggcacgt tgatatttca atggttagat
    10441 acgggattag ctgcacctgt atcgcctggg tcactactcg tgatttttgc caatgcgcct
    10501 tatccacaac tagctggggt aagtataggg atagcaatca gtacatttgt gaccttcatt
    10561 tgtgcagcga tactattgaa attaccaaat aaagaaaaag agaacaaaac ggtcaaagaa
    10621 aggggagaaa tcttggaacc atctatcatt cattccgtca tttttgcttg cgactcaggt
    10681 atgggatcaa gtgctatggg agccgccctg ctgaaaaaga aattagcagc agaaaaaatc
    10741 gatctttctg tcggatacag ctctatctat gaattgaata accaagtaaa tcagctggtt
    10801 atcgtgcaac atgaactagc gggtcttgca agagaaaaag tacctcaaag tcaaatctat
    10861 gtactggatc actttttgga aacagatatc ttgctgtcac gaataaaaga agcgatccaa
    10921 tttccaaagc gggaagaaaa aaagagatag cagatatcac agaacaaaaa acgtcgcctg
    10981 ctaatattgt atttttgtat aaaaacaaca gacgcggctc acaaactatg ggcatgacga
    11041 ttttaagtca attagcaaaa aaagcgaaaa aacagtttgt tatctcaaaa gaatcaatag
    11101 aaaaaatcaa aatccaagaa gaaacgattt atatcgcaca aagagaacta gctgtaactg
    11161 aacagctaga agaaaagatc cctcggctag ttctagttga acattgggta gctacgaatg
    11221 aatacgaaaa actcgtgaag ggagaaatat aagatgtatt tatcgcccag agaaaaacaa
    11281 ttattagcag aatttctcag tagcccgtca cctgtatcta tccaaaaaat gatgaattta
    11341 ttgaaggtca gtaaacggac tatttaccgc gaattagata atcttgaagt ctcattgaaa
    11401 tcggtaaatg cttctttgaa aaaagcagct agaggctcat ttgtcattga ggcatcagaa
    11461 gaagtattag agcaattaaa agaaaataca gatgggaaaa gtaatgactt atccactgct
    11521 aaacgacaac acgcgatttt agccgagttg ttactgacga cagagccgtt gagtcttgct
    11581 catttcatgg aatcatatcg catcagtaat accacttttt atgcagatat caaacagttg
    11641 gaagaaagta ttcgccaact gcctttggaa atcattcgga accagggata cgagatcgaa
    11701 ggaccggaaa aataccgccg gcttctgaca gcgaatgtat tagaattaga aatcaatgaa
    11761 tatgaacttt ttcatagtat ttctttcgat gcatcactga attatttttt tcgattcgtt
    11821 gatccgcaac atctatctct tgcacgcaaa gtaatcgggg aagaattgat ccaaaaaaag
    11881 accaatctaa gtgatagaaa gcttgaacat ttggttttga tgctgacatt gacgatggag
    11941 cgtgtgacga aaaatcattt actgacaaat gagacatata atagtctggc aaacaaagaa
    12001 ttactacaga cagctaaacg attgttttca cggatcgctt ctgagacaaa acaactttat
    12061 ccagtaaatg agatcgtctt ttttgcagga ttattaaatg acttcacgaa ctcatttgat
    12121 cagaatttct ttgaagagac gttcgataca cagcttgctt atttagtaaa acaactgatt
    12181 caagaagtaa gtgaagagac gaatgtccat ttttatgaag atgaaacttt gtacaaaatg
    12241 ctgttgactc atttatctgg tgtgttttca agagccgttt tacaagaaga gacactgacc
    12301 aatccgattt tagaaaaaat catggttcaa tacgaggaag ttgcgaatgc aatccgtaaa
    12361 gcagtagagc ggatttttca agaaaaaaaa ttatccgaag aagagatcgc ttatatggtc
    12421 cttcattttg cgaattcatt ggaacgaagt ccgaaagaaa gcaatatcag tattgcagga
    12481 ttttcgccaa gtggattagc ttctactagc atgttggaac tacgattgaa aaggtatttt
    12541 cccttcatcc aacaaattca tttctatcgg attgctgatt taaaaaaaat cgatttacaa
    12601 gaagaatatg atgttgttat ttctacatct attttaccag gatacggtgg aaaatatatt
    12661 ttagtctccc cgctactgct agaagatgaa gtcaagcagc taaaagaagc tttttcgcat
    12721 attgagaaga aaaaaaggca aaaaattacg tataacagca ataacgagtg gatgatagaa
    12781 gatacttatg aggaaacaat gcatttcatg gatcaaatca atcaattact cggtcgtttt
    12841 tttatccaag aactggataa tcctgagacg atttccgaaa cgattcgcag cttatttcct
    12901 tattttcctg aaggactagt aacggatgaa gaggtggttc atcgccggct gcttaagcga
    12961 tatgaacaag cacctatcgg tattcctcat acaaatatgg ggttattcca tacatccagc
    13021 tcattgattt ctaaaccgat cttttgtatt ttcaatttga aacatccgtt gaccattgaa
    13081 gggatggata gacagccagt cgatttgtcc cgtatgttag ttatgctggc gccttcgcca
    13141 atccaagaaa aagacgggat tcttttagga aagatcagtg gagcaatcat catgaatgac
    13201 ttgaacaccg agatcttccg ctcaggaaat aaagaaatcg tttatcagtt gttagcgaaa
    13261 atcctgattg aagaaataaa gaaatgaagg tgaaaagatg atacagctac cagcagaaaa
    13321 aatattgctc gatcaatcct atcaaaattg gaaagaagcg ttgaccgaga tcggccagtg
    13381 gatgacccaa caagggggaa tcaaaccggc atatatccaa tcaatgatcg aaagacaaga
    13441 aaaagcgagt gtctatatcg ggaatttcgt agccttgcca catgggactg acaaagatga
    13501 agaagtagta gaagaaggaa tctatttagt ccaagtgcct gatggtgtgg actttggaac
    13561 aaaagaggaa ccaaaaatcg cgacactctt atttgtagtg gctttaaaaa aagaacatca
    13621 gttagcggtg ctccaagatt tagccttttt ctgttcagac atcgaccaag taatggcgct
    13681 cagtgatgcg gaaaccattg aagaagtcca aatgattttt gaacatggac atatataacc
    13741 aatgttcaca gtaaaaaaag ctgccttgca tcaagtaata acttcaacca agataaaaat
    13801 aagaggagct atttttgttg ggaggttctt attactgcgg atgcaagctt ttgaaaacta
    13861 tttattctag aaaaccgttt atttgaaata ggggacggtg acaaggtttt tgtcaccgcc
    13921 cctattattt ttgtgtttta atagctcttt tttatataga tagtgcccat acctatgaat
    13981 aataaaacga tactccatat accaagtgtc aagataccat tcatgaaagt aacctgttct
    14041 gaagctagtg gcgagaaaat atctcctcct atgatcacat tttgaaaatc aacataagaa
    14101 gttggcaagt aatgactgat tgattctatc catccaatcg aagaaaacaa gcgatactct
    14161 gctaagaaaa gacaaagaag tgtacctaaa agattgacta gagaatgttc aaataaagca
    14221 gatagaagaa aactgattgt acttaaaaag agcacccaca acaacaggaa cagaaagctc
    14281 tggaaaagat actcatacat cggcaggatt cgtatctcct gaccaatgat cgttcctaca
    14341 ggataacgga agtctcccaa accatttttg attattacta gtatagagac gatcaaaaat
    14401 ggcatcacga gacttagcat agctgcacca taataaatgg taaaacggat gctatgtttc
    14461 tttaccatac tatccggtaa tagattgact agagagatta cctgctttct tttttcataa
    14521 gagatgatgg aagaaagaaa caaggcggtt atacataaaa tcaaaaaact agaaatcatt
    14581 cctgaaaaaa tattttcgta gtaatttgct aaagagagat gcgctggcaa gtcaaaaata
    14641 gaatatcttt ggatctgatg ttctttcata taacggagca actcgacacg tttttgttgt
    14701 tcaatgattg gaattccttg tctttgacca gaaatcagtc gatccagtat atctttttca
    14761 taatgataag ttgcttcgac catttgctgg acattccctg tgttttttgc atgtaagatt
    14821 gcttcgatca gtttgttgct tttctctaaa ctttccacaa attctttctc attctcatct
    14881 tctttcaacg tttcaatcaa acgttgcatc tcttcatagt tatgattcag ttcatcgaat
    14941 tctgtataag caagtttatg atcaaaaaaa agtgggaatg caaagagcac gaccaacaat
    15001 agaggaaata aaaagtttac tttgtttttt agtaagagat tgcgttcaaa tgtaagtaaa
    15061 gacatagtta cacctcatat aatttacgat aaatagctaa aatctcttcc atatttgagg
    15121 attctgtgac gatttctcca ttttttagaa aacatgcttt agaacaaatc gattggatat
    15181 tcgcgatagc gtgggaagaa agaagaatcg tcttcccctc tttctgccat tgtctgatga
    15241 ggctattcaa gatatcaata cttcctgggt ctaatccgtt caacggttca tcgaataaca
    15301 tgacagatga atcactgatc aagtaagcag caagcaagac atgttgtttc attcctagag
    15361 acatttttcc aatcggcaaa gtaaggtact cagtcatctt caatcgttgg aaaacagttt
    15421 ggcattctac tttgctctgc caatagtatt tgatcaaagt caaataatca acagccgata
    15481 gatagtcgga taactgattc gttgattcta gaaaaaagaa agaccggcga taatctgtat
    15541 aagcagtagg agagatgttg tgaagggaca attgatcata agttgttggc agcagttggg
    15601 caatgccatt cagcaaagtt gttttgccaa atccgttcgg ggcaatcaaa gcagctactt
    15661 ctcctgattc tactaaaaga ttcaattgtc gaatcacacg ttttttacca cgtttcatgt
    15721 tcatgttttt gatcagtaat gtcatagata ggcctccaat ataaaattta ataacataat
    15781 agaatggaaa acatctaaat taaatgctaa caaaagttat tgtttgcata ttataaaaaa
    15841 attaaaataa cagttttatt taaaattgaa gttttctgat accgaaatct ttttattttg
    15901 ctgacatact caaacctttg gcacaaagtt tcgtgccaaa gtacgactat ttctcttttt
    15961 agtaagcgga tacaattaga gtatcaaaag gagagaggga gagacaaaat ggaacggacg
    16021 attcccaaaa acaacatttc gctaaaagcg agggtacaaa aattaggcag tactttatca
    16081 agcatggtca tgccaaatat tggagcactg attgcctggg gtgtattaac ggctctattt
    16141 atcccagatg gttatttacc aaatgaggct ttcgctacca tggtaagccc aatgctaact
    16201 tatctgattc ctttattgat cggttatact ggcggaaaag taattgctgg tgaccgcgga
    16261 tcagttgttg gggcaattgc aacgatgggt gtgattgtcg gaacagatat tccaatgatg
    16321 ctaggcgcga tgatcatggg acctcttggt ggatatgcca tcaagaaatt tgatcagcta
    16381 ttccaaaaac ggatcaaatc cggttttgaa atgctagtca ataatttttc agcaggtctt
    16441 atcggttttg gattagcgtt attaggtttt tctgcgattg gtccagttgt cgatgcattg
    16501 actcaagcaa tggcaaaagg tgtagagatc attttatctg cccatttgat tccattgaca
    16561 agtattttta ttgaaccagc aaaaatctta tttttgaata atgcaatcaa tcatgggatt
    16621 ttgacaccat tgggaactga acaagtagca gaggctggaa aatctattct attcttgctt
    16681 gaagcaaatc ctggtccagg acttggcgta ttacttgctt ttactttgtt tggcaaagga
    16741 gcagcaaaat cttcagcacc aggagccatg atcattcact ttttaggcgg gatccatgaa
    16801 atctattttc cttacgttat gatgaaaccg ttattattct tatcagttat aggcggagga
    16861 atgtcaggaa gtttcatttt ccaattgatg gatgctggac taagagcgcc agcttctcca
    16921 gggtcgatca ttgcgattct agcgatgaca ccgttcaatt cttaccttcc tgttattttg
    16981 ggcgtgattg ttgccgcagc tgtttcgttt ggtatttctg cagtaatttt gaaagcggat
    17041 gcgaaagata caaatgaaga cttcgaaaaa tctgttcaag agacaaaggc agctaagcaa
    17101 gcttccaaag gtgcccaagg tattcctcaa ggagctacat tctctggcgt acaaaaaatc
    17161 atttttgctt gtgatgcagg aatgggatca agtgcgatgg gcgcttcgat cttgagaaaa
    17221 aaagtacagg aagcagactt gcctcaaacg gtgaccaatc aagcaatcag ccaactgaca
    17281 gatgactcga atacattgat cgttactcag gtcgaactac aagaaagagc aaaacaaaaa
    17341 gcaccgagcg cgcgttttgt ctcagtagaa aactttttga attcacctcg atatgatgaa
    17401 atcattcaag aattaagcag caagcagaaa acatcagttt ctgaaattga gaatgagcca
    17461 gcagaagagt ttctttcagc aaacatcaaa caaatcaaag agattctact tgtccacgat
    17521 gatcgttccg gatcagcaac aatggggatg accgtgctca aagatatatt agacaagaac
    17581 catttaacta tcccgttaag aaaagtcaat atccaagatt taaaagatga acctgattca
    17641 ctgatcgtag ccaaagaaag tttagcggaa aaagtacaga tggctgcacc tcaatccatt
    17701 catttatcag tcaacagcat ggtcaatccg caaaaatacg aatcgattgc acaatatttg
    17761 aaacagacag cttaagggag gaaaacagca tgcaaagttt gccattcgac atgatcgagc
    17821 tcaatcgatc ttttaaaacc aaagaagaag cgatccgcta ttgcggtcag atgcttgtag
    17881 aagcagggtg cgttgatgag gaatatatcg atgccatggt agatagagac aaaatgttat
    17941 ctgtttatat ggggaatttt atcgcgattc ctcatggaac agatgaagca aaaaaatatg
    18001 tgaaaaaatc cggcatctgt gtcgttcaag taccagatgg tgtagatttt ggtaccgaag
    18061 aagaagaaaa gattgcgact gttttgttcg gtattgcagg agtcggagat gagcatttgc
    18121 aacttgtaca gcaaatcgca ctttattgca gtgatatgga caatgttgtc cagctagcag
    18181 acgcgctcag caaagaagaa gtaacggaaa atctagcaat tgcttaagga gagagaaaaa
    18241 tgagagcagt acattttggt gcaggaaata tcggtcgagg atttattgga gaggttttgg
    18301 cagctaatgg atttgagatt actttcgtag atgtgaatca cacgatcatt gatgctttaa
    18361 atgaaagaaa agaatacgaa atcgaattag cagatgaatc aaaagaaaaa atcactgtaa
    18421 aaaatgtcaa aggaatcaac aatcaaacaa atccagaaaa agtaatccaa gaaatcgctg
    18481 aagcagattt agttactacc gccattggcc cgaatatctt accttttatt gctgagttga
    18541 ttgcaaaagg tatccaagaa agagaaaagg aaggaagcac aacatcttta gatatcattg
    18601 cctgtgaaaa tatgattggc ggttcagcat ttctagaaaa agaagtgtat aaatatcttc
    18661 cggaaacatc atttactgac aaatatatcg gctttccaaa tgcagcagtc gatcgaatcg
    18721 tcccattaca acaccatgaa gatcctttat tcgtccaagt ggaacctttc aaagaatggg
    18781 tcattgacga tagccaaaga aaaaataaaa aaatccaatt aaaaggggtt ttatatgtag
    18841 atgatctaga accatatatc gaacgcaaac tatttagtgt caatactggt catgcgactg
    18901 tcgcttatac aggtgccttg ttaggttacc agaccattga tgaagcaatg caagatgcgt
    18961 tagttgtggc acaattaaaa tcagttttgc aggaaacagg aagtttgctg attgccaaat
    19021 gggggtttga tgcagagcag catcatgcgt atattgaaaa aatcattcat cgcttccaaa
    19081 acaaaaatat ctctgatgcg atcacacgtg tcgctcggac accattacgt aagttaggtt
    19141 atcaagaaag atttacacgt ccagtgagag aactacaaga acataacttg acttgcccac
    19201 atttgacggc aacaatgggg attattttta attactatga tcctgaagat gaacaaagcc
    19261 gtcaattgca tgaaatgaag atccatgaaa acttggaaca attgattcaa gaagtcacag
    19321 gaatcaatga tccgaaaaca atcgggaata tcaagcaaaa cgtgaaccgt tatgccaagc
    19381 aagtcgctta aaataggata cgaaaaaggg gaatgtgacg aaatttttgt cacattcccc
    19441 tttttcgaat aactaggctg tttgtccttc aagatagggc agatccaatt ctttaccgta
    19501 acgttgttct aaagctaggc ggatcaaacg agctgccagg ttctcatttc ttgcaaggat
    19561 aggtccatgg aaataagaac cgaagacatt tcggtaaatg acaccttcag attggtcttc
    19621 accattattt ccttgacctt gtaccacttt ccccaaaggt cgttcacctt cacctaagaa
    19681 agtccgacca ttgtggtttt caaatccata ataagtttca ttgaattctt cgttatggat
    19741 aacgatatca ccgataaacc ggttattttc ctgacttaac gtgtagtgat ccagtgcact
    19801 gattccttgg atcttttctc cattagctcc catgtagtag tgacctagca attggtagcc
    19861 accacaaatg gctaacatga cgccatcatt ttcgatatag ttgatcaaag aatctttctt
    19921 tttctggatg tcttttgaaa tgattaattg ctcaaagtct tgaccaccgc caaagaaaac
    19981 caagtcatat ttatcagcat caaaaggttc atgtatacta acgatctccg tatggcaaga
    20041 aacccccatt ttttctgcta tatatttcaa catcaaaagg tttccgttat caccatatgt
    20101 gttcatcaaa tttccataaa ggtgggcgat attgagttca taattagcca cggttcattc
    20161 ctcctttgat aaatccttga gcagctagtt ctttacgaag ctgcaataca gcagtgtaag
    20221 tagctaaaat atagacatgc tcagttggca attctttgat tttttcgatt acttctggta
    20281 attcttttgt ttctgtcaat ttattttctg gaatcccggc aacttttaga cgtaaagtca
    20341 tatctgtatg acggtctcct ccagaaataa cagctgggat atccatatcg gcaaagtttt
    20401 caaaattacc atcccaaatc cagctgacat cgattccgtc tgcgtaattg gcatttaata
    20461 aagccactaa agaaaatgga taaggagcta gaccaatcat atcgattact tgattgatac
    20521 ctacaggatt tttgacaagt actaatgtac attttttccc attgatattg atgacttctt
    20581 gtcggccgaa tactttctcg tcatatccta aaccttgttt gattttatca ggatcgacat
    20641 tgaagtactc tgccactgca gtagctgcta aagcattgta gacattatac ataccgccaa
    20701 cttcgattcc gtattcatga ccatcgatca cgaaatctgc tgacacattg tccatccgta
    20761 ccatatcagt taatcgataa tccaattcag gacgtttgaa gtcacaattt ggacagtaat
    20821 atttccctaa gtttgcataa gtgatcattt tataatgcaa gatgtgatga caatttggac
    20881 ataagacacc gtctgtattg taatgagcca tttgttcacg atcttcttca tggtcaaagc
    20941 cataatattt tctaggattg actgtttcga tagaattgaa gattggtgaa tcaccgttac
    21001 tgataatcgt tgcatttggt gactttgcgg caccgtctac aatcatttta taggtcgtat
    21061 agatttctcc ataccgatcc atttgatcac ggaaaatatt tgtaaataag aacagttctg
    21121 gtttcatata ttctgtgact ttgctcaaac ttgcttcatc tatttctagg acagcaaact
    21181 ttttctgtcc tttttttggt tttgcctgca agaaagtcga tacaattccc tgtaccatat
    21241 tcgcaccagt agggttggtt agaacttcat cgaattgctg gcgcaaaata ttgactgtta
    21301 aagcggtagt caatgtttta ccgtttgttc cggtgacaac gacgacttgg tagtcttttg
    21361 ccaaactatc tagtatatgt ggatcgactt tcagcgctag tttacctggt aaacttgatc
    21421 cgcctttaaa aaaagttttt aatgcccatt gcgacgtttt tccaactgca atcgcaaaat
    21481 gactgcgtat tcccattatg taacctccaa aaacgatttg ctgacgaata aattcaacta
    21541 atcataccat atgttgaaaa aaaggttaaa ttgcttttct tattcttaag aaaaggttac
    21601 ggctgaaagt gcatgaaatc ggacaaaatc gcatgattta acaaaaaaac agcttgaaac
    21661 aaaatgattg tttcaagctg ctgtgatttt attattccct cttacctata ttcccatttt
    21721 aaccgataat aattttctcg cttggatatt catagcctag atctcgtgtt tcttttggca
    21781 cgaataacat caatgtatat agcattccga tccgcccaat aaacatcagt gtagcaatcg
    21841 tgattttgcc cacaacagac aagtctccgg taatccctaa agataaacca gttgttccaa
    21901 acgcagaagt tacttcgatg atgatcgaga tcagcgtttg ttcttctgta gcagataaaa
    21961 aaacgataca aaagaaacac ataccaagag aaagcataaa gacaacgact gattttcgca
    22021 catcatcttg atcgattctc cgtccaaaaa tattgatgtt atcttcactt ttgaggaagg
    22081 aatatagata caaaccgatg attgctacag tagttgttcg aatcccgccg cctacagaac
    22141 taggactgca tccgataaac atcagtaaag aaaaaatgat cagtgttgtg atttgaaaat
    22201 cacccaaatc gtgaatctgc agaccagcat tacgagtcgt aatcgaataa aacatcgaat
    22261 tgatccattt gacactcata ttggaatctt ggaataaatg gtccttttcc aatagataaa
    22321 tcaagacagt tcccgaaaca aacaagataa caaaagctaa cacagctaat ttggtaaaca
    22381 aggaaaaacg aaacggaagc ttcgcattgg aacgtttgta taatagccat tcccggcact
    22441 ccatcaatac aggaaaacca attcctccga caaaaatcaa aaacatgatc aggatcaaga
    22501 aaaaatagtc atgtgcaaag ggcttgatgg aatccccagt gacgtcaaac ccagagttcg
    22561 tgacagccga tatcgcctga taaaaaccgt aaaaaacggc atcacgccaa cgatcaaaat
    22621 agcctctgta ataaaaataa atagaaaaga atgtcccaaa aagtaattga aaccagatta
    22681 aaatagcaaa agtgatccga atcagtcgga cgataccaga caaacgcggt tgattcatat
    22741 ccgtcatgat cagctgtcgc tgtttcagtg tgatccgtcg tttagaaaaa atgacaaaag
    22801 cagtagaaat catcatgatc cccaaaccac caacttgaaa taatatttcc agcagtataa
    22861 taccgttatc attgaacaca gaattgatat caaaagtcga tagtccagtc acactcactg
    22921 tactgattgc catgaacagc atgtccacaa aagaaacatg gctatctggt tcgcgaaaaa
    22981 tcggcatata aaatagaacg agtgataaga ccgtcatcaa tatataataa aaaacgatga
    23041 tttggatcga tgagaaatga ttggcagcaa acttctgtcc tcgccgctgc agccttcgaa
    23101 agaataaatc aacatgcaca gtactatcct cctgacaata gtcgtttcta ccagtataca
    23161 aggggaatta ggaatactca aagaaattat caaacagata acaatacagc tttcgattaa
    23221 aatagaaatg gcttataata aggaaaatcc tagaaaaaag aaggaggagg aataacaaat
    23281 tgattaatgc tcaacaaatc gtagaaaaaa tgaaaaatca aaaaataaat tatgatacag
    23341 ttctgaaaaa aatgatcatg caatgggaga aagaagaagt aaagcctaag atattaatac
    23401 atacatgctg tgctccttgc agtacgcaca cattggaatt catgtctcaa tatgcagaga
    23461 tcacgttatt tttttcaaat tcgaatattc atcctaaaag tgagtatttg cgaagattac
    23521 atgaacaaaa acgatttgta gaccaattta atgagaaaac tgaccatcat gttgcgctaa
    23581 tcgttgatga ataccgtcca aatgaattca ccaaaatggt tttaacaaac catcttgaaa
    23641 acgaaaaaga aggtggtgct cgctgcagtg catgcttcaa tatgcgatta gatcttgttg
    23701 cgcaaaaagc gcaagaacta ggatacgatt actttggaag tgccctgacc atctcgccaa
    23761 agaaaaatgc agctttgatc aatcagatcg gaatggatat ccaaaagatt tacgggacac
    23821 aatacttgcc aagtgatttc aagaaaaaca aaggctatga acgctctttg caaatgtgca
    23881 aagagtatga tatttatcgc caatgttatt gtggttgcgt gttcgctgcc aagcagcaag
    23941 gatgcgatct gaaagaaatc aatcgggaag caaaagctta cttaaaaaca tcaaccgtag
    24001 tttttgagga aaattaaaga aatctttcgg aaaaacgtaa gaaaaaaata aagaatttat
    24061 ggtagaaata aggtagactg tataatttgt ccgtagtaaa gtaaggaaac aagaataaat
    24121 ttcaatgaag gaagagataa gatgcgaaaa gtagcaccta ttttgaagcc aatcgctgta
    24181 ttaacaatct cgacgattgt cgcgactact acaggtattg tgaatagttc cagctaccgt
    24241 gcaccaagtt caagttctag tactgtagaa gaaacaacac caactacttc agtctcgaca
    24301 tctgaaccaa caacaacgga aagtttgaat gaaaccacta cgacaagtac atgggacgat
    24361 acaacaacta gttcgtcgta tgatgagaca tatacaactg acagctcaag cgaaacaagt
    24421 aatacggtac cagatggcac tccatcggat tcaaccaatc caagtacaag tccggataca
    24481 agtgctagct ccgaaacgat accaagcagt acgactgtag atgataacac gcaaaatgat
    24541 gatgcagcac gtacagcaca gcaaaaccaa gattcaggaa atacccaaac gtataaccag
    24601 caagcaggtg attctcaatg acatttttac tagaccttat caacggggtg cataaattcc
    24661 ttggctattt agacatcagt cctaaatatc ttaaccgtgg atatacgatt ttaagtgtga
    24721 ttcccacgct ttatttattg agaattgttt atggactttg gcaaaaccaa aactatcttc
    24781 aatttttctt atatggactt gcatttctag tgcttgttta ttttactgtt ttaaatgtat
    24841 tttattactt tttagataaa aacacgaaag ccgatgtcac tcagcttttt gtgaagtatt
    24901 tacctgatga agcgttcaac atccagacag aagaatcgat agataatgga aattcgatcg
    24961 ataaagtgaa tacacaagag gtcatggttt cttatgacga agattatcaa ttgaaattag
    25021 ccgagaatat gcggtatttg attggaaatg gtgagatcaa aacaaatgaa ctcggtcgca
    25081 tggatggatt tctggtcgat agaaatacat tgtatcctta ttactatgtc aagaaaacag
    25141 gagagaaaga gtatgttcta aatattggac gaagctactc ggacatggaa aaagtaggga
    25201 ccattcgact tgactcaaca gaagacacat tggaacctgt cggattgttc atcgtcggcg
    25261 gtgattttgt caaagacggg ttacgctatc atgagcctta tcgtctgaaa ttgattgcaa
    25321 aaaaggcaca gtcgcaggaa gaaccagtgg tttatagtcg tagccaaaga agaagacatt
    25381 cataatgtga tgaaacgccg tgtatcagtg gttgcgataa aaacgtttat tcggaataag
    25441 ggggatgtga cacgtctttt gtcacgttcc ttttttatat aacgagaaag ataagacgaa
    25501 cacatcactt attctttcct ttcatttata aacattgtag aataaagaaa gtacaacgaa
    25561 gtattgtgaa aaaacgtaat aaataacgag gaaaatacaa gtaggaggta agctgtgaaa
    25621 gaatttttga aaaattgggg gattttgatc cttgtattag cggctatttt attagctaga
    25681 gtgtacgtgt ttacaccagt tactgtaaac gggcattcga tggaccctac attaagtgat
    25741 ggacaacgat tgatttcatc taagatctca aactatgaac gaatggatat tattactaca
    25801 aaggaaccgg gggatgaaga acggatgatt gttaaacgga tcatcggtat gcctggagat
    25861 acagtcaaga tggaaaatga ccagttgacc attaatggca aaaagtatga tgaaccttat
    25921 ctggatgagt tcaaaaaaga attttcagaa gataagttac aaggagaata tgcttatagc
    25981 tcaggattcc aagcacaagc agaaagttca tccaccttta cgagtgactt tgaatatact
    26041 gtgccaaaag gaaagtatct tgttctaggc gataaccgct tgatttcaaa agacagccga
    26101 atgtttgggt tagtcgacaa agatatgatc caaggaaaag ttgttttccg ttattggcct
    26161 ctttcagaaa ttaaaatcat gtgatgaaaa aataaaaaga agctgtgaca tgttttttgt
    26221 cacagcttct ttttccgaaa attccttctt atttcttgga gttgctcact ttttttgcaa
    26281 tctcatttta agctttttgg ctgatggata agaaaagcga agcgtttttg ttcataaata
    26341 gcttttcccc acgatggaag gtatgactag tagcagagac aaagcccgtt ttttccaatc
    26401 gattattcaa ttcttcttgg ctaaagccat tatggacttt cggatgacta atttgttcat
    26461 tcttgtcaaa gtctacgatg atcaattgac cgccaggagc taaaatttca taaagttttg
    26521 taagaatatt ctccgtatca ggaatgtgta aaagtacaag tgatagaagg atgagattag
    26581 cttggacagc aggaaattcg acagaagcat cagcgtggat cgttcggaca tttttcagat
    26641 ctgctgcttg gatcttttct tctgccattt tcagcatagt ttctgaagca tcggcaatga
    26701 tcagttcttt gaatctttcc gcaagcggta aactaacaag cccagttccg cctccgtaat
    26761 ccagcaggac tttttggtgg ctgtcgcgcg gtagataagt agttagttct tcgcgaataa
    26821 tcttggctaa tgcttgacgg tcaggggaat cataatggtt agcgatggaa tcaaaaatat
    26881 tttttgtcat caaatagctc cttacgtaaa actttgaaat tttaacttat tatagcacgt
    26941 gaaaagaaag aaagcatgct atactcaatt caaaaaggga gaatctagaa agaatatgcc
    27001 gatatcgttt gtaaaagata gagaggaaaa aggaaagtgt gtccgagaaa tattactaga
    27061 cttgcctgag tggtttgggc ttcctgaatc aacggaaaaa tatatcgagg aatcaagtaa
    27121 actaccttta tggtgtgaaa aaagaaaaga agaatattta ggctttatca ctctttcaca
    27181 gacaagtgaa gatactgccg aaatctattc tattgtatgg gaataaaaaa agactatcat
    27241 caccaaggat taggaacaaa actttttaaa gaagcagaag gttacgcagc aaaacattac
    27301 aaatatttgc aagtgaagac tgtagacgag gggcactact ctatatatga tcaaactatt
    27361 tgtttctacg aatcattagg attttcaagg ttggaagttt ttccaaattt atgggatgaa
    27421 tggaacccat gtttagttct tgtcaaaaaa ttggaacaaa agtgagcaat agatttaata
    27481 ctaatctgtg cttgatgaaa attctcactg taaaaaatgc tgaaaatcaa gtataatacc
    27541 ataggaacaa actggaaggt gaaaaagagc atggcacaac tattttttaa gtatggcgca
    27601 atgaatagcg gcaagacgat cgagatccta aaagtcgcac ataattatga agaacaaaat
    27661 aagccagttg tcttaatgac aagcggtatt gatacaagag atggtttagg cgttgtttca
    27721 agccgaatcg gactgaaacg taatgcgatg ccgatatttg aagaaacaga cgtatttgac
    27781 gtaattcaga aaatggaaag caaaccctat tgtgtgctga tcgatgaagc gcaattctta
    27841 aaaaagaaac atgtcattgc ttttacgaga attgtggacg aattggatat tccggttatg
    27901 gcatttggtt tgaaaaatga ttttcgaaac gagttatttg aaggatcaaa atatttattg
    27961 ctttatgcag acaaaatcga agaaatgaaa acaatctgtt ggttctgcca caaaaaagca
    28021 atcatgaatt tacattatat tgatggaaac cctgtttatg aaggcgatca agtgcaaatt
    28081 ggcggaaatg aagcttatta ccccgtttgt cgaaaacatt actttcaccc atcaatgatt
    28141 acagaaggag aataagcatg tacgatcaat tacaagcaat tgaagaccgt tatgaagagc
    28201 ttggagaact tttaagtgac ccagaagtga tttctgatac aaagcgtttt atgcagcttt
    28261 caaaagaaga agcaaacacg cgcgaaacag tcgaagttta tcgtcgttat aaagaagtag
    28321 tacaaggaat caccgataca gaagaactgc ttggtgaaaa actggatgat gaaatggctg
    28381 aactagcaaa agaagaatta tctgaattaa aaaaagaaaa agaagtctta gaagaaaaaa
    28441 tcaagatctt gcttttacca aaagatccaa atgacgataa aaatatcatc atggaaatcc
    28501 gtggagcagc aggcggagac gaagcagcat tattcgctgg cgatcttttc aatatgtacc
    28561 aaaagtatgc tgaagcacaa ggctggaaaa cagaagtgat ggaagctaac gttaccggaa
    28621 tcggtggata taaagaagtg atcatgatga tcaccggaga caacgtatat tcgaaattaa
    28681 aatatgaaag tggtgcgcac cgcgtccagc gtgttccttc aactgaatcg caagggcgta
    28741 tccatacttc caccgcaaca gttgtcgtga tgccagaagc tgaagaagta gagatcgata
    28801 ttgaagacaa agatatccgt acagatatct atcatgcttc aggtgctggc ggacagcacg
    28861 tcaataaaac agcatctgct gtacgtttga ctcacttacc aacagggatc gttgttgcta
    28921 tgcaagatga acgttctcaa atcaagaacc gtgaaaaagc aatgaaaatc ttgcgtgctc
    28981 gtgtgtacga taagatccag caagaagcac aaagcgagta tgatgccaat cgaaaatcag
    29041 cagtcggaac tggggatcgt tcagaacgga tccggacgta taatttcccg caaaatcgtg
    29101 tgactgatca tcgtatcgga ttaactatcc aaaaattaga tcagatttta gcagggaaat
    29161 tagatgagat cgttgatgca ttgatcatgt atgatcaaac atcaaaactg gaagctatgc
    29221 aaaatgggta aaatgaccta tcgagaagtc ctgtcacggg cttcttcttt tttagaggat
    29281 catgggaaag aagcatatag tatccaattt ttatttttgg aacgaaaaca atggaaaaaa
    29341 cttgattggc tccttcatat gaacgaagag atttcagaag aagaacagcg gttgatcgaa
    29401 accgatctgc gacttctgct tgcagatcat ccacctcagt atttgctagg atatgcagat
    29461 ttttatgatc atcggttaaa ggtaactgaa gcaacactga tccctcgacc agaaacagag
    29521 gagttagtcg aatggtgttt agacgagacg cctggtgtac cgttagaagt gatagatatt
    29581 gggacaggga ctggagcaat tgctattagt ttgaaagcag caagaaaaaa ttggcatata
    29641 tctgctgtgg atctttcaga agaagcatta gaagtagcga aagaaaatgc tcagaaagaa
    29701 ggaacgaaaa tcagttttta tcatggagat acattaggac cagtaatgga tcagcaattt
    29761 gatgtgatta tttctaatcc gccgtacatc agtcggaatg aatgggaact gatggatgaa
    29821 agtgtccggt cattcgaacc taaaatggcc ctttttgctg agaacgatgg attagctatt
    29881 tatgaaaaaa tagcagttga agcaccaagc gtactaaaat caaatggaaa gattttttta
    29941 gaaatcggat ttcgccaagg tgaagcagta aaaaaaatat ttcagcaagc atttccagat
    30001 aaaaaagtgg cgataaaaaa ggatcttttt ggcaatgaac gaatgatcca agtttatggt
    30061 tgaagttgtg gatgaaaaat tttttatttg tttttttatt ataaaaaaac acttatttga
    30121 caaggatgta aacgactttt tggtttatca acaagtttat ccactattga caaatagatt
    30181 atccacaaac agtggaaaac ttgaggataa actcagacaa aataagaatg tatgaaaaag
    30241 gggttgtgga taaactgtgg aaacgaaacg atatgatgaa acagaattgc aagaggcagc
    30301 cgaagcactg aaagaaggag aacttgttgc ttttcctacc gaaacagtat acggattggg
    30361 cgccaacgct cttttaccaa acgctgtcaa gaaagtgttt tctgtaaaag ggagaccgca
    30421 agataatcca ttaatcgtcc atgtcgcctc ttttgaacaa gtaaaagagt atgtggacaa
    30481 ctttcatccg gcagcagaga agattgtgaa gaacttctgg cctggaccat taactttgat
    30541 atttaagatc aaaaaagaca ctttgccctc agttgtgacg ggaggattat ccacagctgc
    30601 atttcgtata ccggataaca aaaaaacact agaagtaatc gaactttccg gtgttccgct
    30661 tgtcggtcca agtgcaaata cgtcgggaaa accaagtcca acgactgcag atcatgtata
    30721 tcatgatcta caaggaaaaa ttaccgggat tattgatgat ggagctacgc gaattggtgt
    30781 agaatccact gttcttgatt taagtgatcc aacagccatg cctatgattt tacgaccagg
    30841 tgcagtaacg aaagaacaaa tcgaagcagt catcgaatct cctgttgcta ttgatcagca
    30901 tcttgtaaaa gaaaatgaaa caccaaaagc ccctgggatg aaatacaaac actactcacc
    30961 cgatacacgt gttctgatgg tcagagatgg cgattggtca actgcagttc aatgggcaaa
    31021 aaataagaag atccgtgcag gtgtcatagc aagccccgaa attgcggatc aagtgcggac
    31081 agatactgca gctgtttata tgtataacga caactcagta gaagcggcgg ctaaaggatt
    31141 gtttgcaggt ctaagaggat tagatgaacc aacacttgga ttagatttga tttttgtaca
    31201 agtgtatcca gaaactggat tggggaatgc ttacatgaat cgcttgaaaa aagcagcagg
    31261 acaaaattat tttgaaaaat gatcaattgg ttattgtcgc attcttttag tatgatacaa
    31321 tgctatcaag taaatcttct atcagtgaac gaaaaactaa gcgtaactaa tcgtaataga
    31381 agagatacga atatttggca atttgttttt gatgggaaaa ataaaattgt aggaaaataa
    31441 aaaggagctg ttgtttgtgg tagattacaa aacgtttgac cctgatcttt gggctgcgat
    31501 cgccaaagaa gaagaaagac aagaacataa tttggagctg attgcctctg aaaactttgt
    31561 ctccgaagca gtgatggctg cacaaggaag tatcttgaca aataaatacg cagaaggtta
    31621 tccagggcat cgctattatg gtgggtgtga atttgtcgat atcgttgaaa atttagcgat
    31681 tgaccgtgca aaagaattat tcggagcgaa atttgcgaac gtccagcctc actccggctc
    31741 tcaagccaac acggctgctt atctcgcttt ggtagaacca ggggacacga tcttaggaat
    31801 ggatctttcc gcaggcggac atctaacaca tggatcacca gtcaacttca gtggcaaaac
    31861 ctatcacttt gttgcttacg gtgttgatcc gacaacagaa gttattgatt ataatgtggt
    31921 acgtatttta gctagaaaac atcaaccaaa attgatcgta gcaggtgcca gtgcttacgg
    31981 acgaacgatc gactttgcga aattcagaga aatcgcagat gaagtaggcg caaaactgat
    32041 ggtagatatg gcacatatcg caggattagt agcagcagga cttcatccta atccagttcc
    32101 ttatgcagat atcacaacga ctaccactca taaaacattg cgtggccctc gaggcggcat
    32161 gattttgaca aacgatgaag cattagcaaa aaaaataaat agtgcggtat ttcctggtat
    32221 tcaaggcggc cctctagagc atgtgattgc gggtaaagca gtagcattca aagaagcatt
    32281 agatcctgca tttaaagaat atagtgaaca aatcatcgcc aatgcaaaag caatggtcaa
    32341 agttttcaat caagcaattg gaaccagagt catttcaggg gcgacagata atcatctgat
    32401 gttgatcgat gttcgcgagt taggtataaa tggaaaagaa gcagagagca ttttggacag
    32461 tgtgaatatc actgtaaata aaaactcgat tccttttgaa acactaagtc cattcaaaac
    32521 aagcggtatt cgaatcggca cgccagcaat cactactcgc gggttcaaag aagaagatgc
    32581 tgtaaaagtg gctgaactag ttgtcaaagc attacaagca aaagatgata acgctcaact
    32641 agacgaagtc aaaacaggtg tacgcgaatt aactgaaaaa tttccgttgc ataaaaaata
    32701 aaaatttaaa ttccattagt aaacagaaaa gttcaatgtt gggcttttct gtttattttt
    32761 tgggaaaacg gattctttga caatatcggt gatgctctct agtatatgag gtgtaatttt
    32821 agtcttcaca ctaaatctca gggaggaaaa gtcatgactg atcgtatctc gttagaaaag
    32881 gaagcagtag cattcagtga tgcaaatgcg cctcatccgc gtatctatga actagcaccg
    32941 gaagaaggaa gagttttact agaagaagta caagaatcac ctgtgaacaa atattccgtc
    33001 gatattgaag acttgatggt ggatactggc gaatggggaa aactcaatat tcgtctcgta
    33061 cgaccagaag ggaatatgga taaattacca gttatttttt atattcatgg agcaggctgg
    33121 gtttttggca gtgctcaaac ccatgataaa ttgatcagag aacttgcggt tcgtacgaat
    33181 tccgtcgttg tctttccaga atatagtcga tcaccagaag caaaatatcc aacagcaatt
    33241 gaacaaaatt atgctgtgtt gcaacagctg aataaattag ccaagtcaaa aaatctggat
    33301 ctcgagaatc taatcgttgc aggagattca gtaggtggta acatggctac agtcatgacg
    33361 atcttaacaa aagaacgaaa gggcctccca atatccaagc aattgctgta ttatccagtc
    33421 acaaacgctg attttgatac agattcctat catgaattcg gagaaaacta ttttttgaca
    33481 agagaaggaa tgatgtggtt ttgggaccaa tatacgacga atgaagaaga gcgtgctgaa
    33541 atcacagctt cgcctttgag agcaaatata aatgaactaa atgatcttcc ttcagcaatg
    33601 attttaacgg gagaagcgga tgtattaaga gatgaaggtg aggcttatgc gcgcaaactt
    33661 cgtgatgcag gggttcctgt tacacaagta cgcttccaag gaatcatcca tgattttgtc
    33721 atggtaaatg ctatggatca gacaaaggca acgcgtgcag caatggcatt atctacttct
    33781 tggatcaaga aaaaagaata agctttgctt gtccgcagga aaacttcttt tcaaaaacgg
    33841 attttcttag gaaaaatggc gagtttgact agtcaatcac ttgattttgt tttacaatta
    33901 aaaagaaacg acagaacaaa ggagagctta aaaaatgggc aaatttcaag tgatcgatca
    33961 tccattgatt caacacaaac taactattat tcgggacaaa aactgcggaa caaaggtttt
    34021 tcgtgaagta gtcgatgaaa tcgctatgtt gatggcatat gaagtatcac gggatatgcc
    34081 attggaagac atcgtgatcg aaacaccgat cactgaaaca acacaaaaaa cgttgtctgg
    34141 taaaaaagta gcgattattc caatcttgcg cgcaggtatt ggaatggttg acggtatctt
    34201 ggaattgatt ccagctgcta aagtgggaca tatcggtctt tatcgagatg aagaaacatt
    34261 ggaaccacat gaatatttcg tcaaacttcc agaagacatt gatgcacgtc agttgtttgt
    34321 agtagatcca atgttggcaa caggcggatc agcaatcatg gcaatcgatg cattgaaaga
    34381 acgtggcgcg tcgaacatta aatttgtttg tttggtagca gcacctgagg gagtaaaagc
    34441 tttgcaagaa gcgcatcctg atattgacat ctatacagct tctctagatg aaaaattgaa
    34501 tgaacatggt tatatcgttc ctggactagg ggatgcgggt gaccgtttgt ttggtacaaa
    34561 ataagtaaat acgaaaaagg gtgtgacaca acttttgtca catccttttt tggtcatttt
    34621 taacgtttga tgcagaacag ctttttcaca gctttcgttt gcatataaaa aaaccatccc
    34681 aaaaatgcag agatggtcaa attcaaatct tttttagttc tttgtagtta acgattacta
    34741 cacccttact ttgcgtcatc aagttcgcat tttctgcagt ttcatcaatc tcaacaacag
    34801 cggaattttt caattgcttt gaaatcgttc cagtttgcga cttgccgtga attgtgaaca
    34861 ttacgtgagt attgatcttg aatttttcac caatttccga tggtacgata gttgtatcaa
    34921 attttccaaa agttgccatt ttcataaaac ctgcctttca catcaattat accacgtttt
    34981 atgaaaaata tcatgaaatt aaactaattt tccatcggac tctttacaat cagccaaata
    35041 gagtatataa tttcttttgg ataaggccag cttagctcag ttggtagagc aacgcactcg
    35101 taacgcgtag gtcgtaggtt cgatccctat agctggcatt aaaagagaag acagatatat
    35161 caaggatttt taatccattg atacatctgt ctttttgttt aaaggaaata aagtatgctt
    35221 tcttagcaat agagcatgta ttatttctat aaaaatttag gagaataaaa cgactagcaa
    35281 tatagctgtg aaatcaaata tcacatgaac tgcccaactt gtaatgatcg agttgctttt
    35341 aatggcagct tggttgaata acaatcttgc caccccttgt atcaaaagga tgtgtgctac
    35401 agtgtgtaaa atatttccat tatcataagt actgtaatgg ataaatccaa agatgattgc
    35461 tgacaagaaa ctagcgacag gaatgctgaa cttactagaa aaaatagcga gaaaatacac
    35521 tgagaacaat tcttctccaa gtatcatgat aggcaaaata ataaataata acgggctgaa
    35581 agcctcattt attggattgc ctgttaaacc ccatttcaaa atttgttgca aaaataccga
    35641 gactgcggca ctgattacta cattgataaa aaaatatttg gctatatttt tgacaggagc
    35701 gacaggtttc gagaacattt ttttcgtatc ttttttacca aaaacaagtg taaatgctat
    35761 aaatccagtg atagttaaag aaaaaatgct aataatggat ggcgcaaata gcaaccctaa
    35821 caaaccgagt acaacgacaa tagtgcccaa tatccctttt ttaagttcta ttttttttcc
    35881 taaaatgtta ttcatgataa taactcctac tattcagttt ttgaagatag agtcagtata
    35941 catgaagagt taaaataggc aatgtttttt tatggatatt tgtattgcta aaaatttatc
    36001 ttatatattc attttgatta tactactttt atttgtaaaa attttctagc aaaaccaagt
    36061 gcttgcaact gattaagcgt acaatttttt agatgttccg agcgtacttc aatcatttca
    36121 aaggagttgc tacttaaatc gatatttttt aaatcagtat caaaaaagct agcattttct
    36181 aaatcattag tagaaaacat tattttagtg agggaacagt ctacaaaatc tgcgcttgat
    36241 aagacagagt gctcaaaggt actttctttt atgtttgaac cagataaatt tacatagtcc
    36301 attttacaat tctcgaataa cgtgttccca atataacttt ccatcaattt agtacctgtt
    36361 aatttacaat tgacaaattt cacgcgatgc aacatgcttt ttgtcaatat acagcctgaa
    36421 aaatcacagt tttcgaatat acagtcggta atctccattc tttgaaaatc attggaagca
    36481 aaaaatgcat acttgaaaat agatttgtaa ataattggat ggcagattat ttggttttcg
    36541 atgacctctt tttgtgaaag gatattatac agttcaaaat cttcgttttc atagatatga
    36601 aaaaaggatc ctttattcaa gcttgcttca ttaactttag gaaaaatcat atttaattac
    36661 ctccattttc ataaagtcat attaacaaaa gctaaaccaa cttacattag cagaaaatga
    36721 gataggtttt cgcctttttc gataacgata gtgtcgctat ctcttgaaac gttcttagaa
    36781 ttgccctgag agacacaaat taggcgtaat tctaataaaa atcttagaat aaaaattttt
    36841 actgatttaa tttagaatgt ttttaaaata aaaatcgttg ccataacagt gtattgaaag
    36901 gttttaacaa tccagtaatg atttaaaaaa atctagatgt agcgtatact ttgtttatag
    36961 aatgtagtgg gaagaaatat atttttggga ggaaatcgtg atgtctaaaa gtgaagaaat
    37021 agaaaacatg gtactaaaat tatatgatct cgttttaaat ccagagatca aagaaaagga
    37081 acgtatactt ttgatagacg caaagacagg cttagaaaaa ggtcagtatt atcctaaagt
    37141 cataaataat ttggaacgta gtttacgtcc gttagcaatc aggggagaat tgtctaaacc
    37201 agtatcaccg ttttatatgg agatatcaac aataggaaaa tttgaaaaag aattaggtcg
    37261 aggaatggct tcggcaccga ttacttttgg gcatttataa aaacgagtta ttcatctcaa
    37321 tgaattaaaa agtatagtca atctcataat gcaggctagg ttcatttatt tgaacagagt
    37381 ctgtattttt ttattctaaa taaagaaaca gatgtttctt tatattgtat tttatccttt
    37441 aattaacaca aaaacagcta gtataaacta ataatgttaa ttaaaagtgt attttatgaa
    37501 actatcgtta tttattaatg ttgcattttt gtaagttaaa aattggaaat atagattgaa
    37561 aaaatgaaag caataagtaa aataaaatga atatatgcga aaaaataatt tacattagga
    37621 aaaaccttgt aaaaacagtt ttttggcata tttatttttt ataaatattt gtaaaataac
    37681 tatcaatttt ttagttaaaa gattggaaat gagtggggga ggaattgaag aaaggatttt
    37741 tgagagatga t
//
LOCUS       DARPZF010000022        35876 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.023, whole genome shotgun sequence.
ACCESSION   DARPZF010000022 DARPZF010000000
VERSION     DARPZF010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.023"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..705)
                     /locus_tag="SLE65_001453"
     CDS             complement(<1..705)
                     /locus_tag="SLE65_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEI8448753.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFI"
     gene            1393..1551
                     /locus_tag="SLE65_001454"
     CDS             1393..1551
                     /locus_tag="SLE65_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8448754.1"
                     /translation="MNKKQTCEFLGIDNNTLDKWIRIYNFPVIRIDGIVRFDIEDIKD
                     FMNTFKTI"
     gene            1623..2849
                     /locus_tag="SLE65_001455"
     CDS             1623..2849
                     /locus_tag="SLE65_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEI8448755.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGITSEKYQKVFPTRQLAIKA
                     ENAMKRKIETVLREENANSLELKGKIKFKEFYESKWLPRYELGQTTRSKRAPSYVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQCITAPKKIALEERRIREGNQALSSEELIAWIEAVNTDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFEKQTVRLKHALDKYQKKKFTKGRKDTV
                     IQVPEIVMALLSKWKSVQAEQLLRLKINQTPDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPELAHLSPHKLRHTYATIARQGGANMNQISSALTHSDISTTRIYVNTPDVV
                     DKTVFEAFQRGLNKCD"
     gene            complement(2938..3330)
                     /gene="rpsI"
                     /locus_tag="SLE65_001456"
     CDS             complement(2938..3330)
                     /gene="rpsI"
                     /locus_tag="SLE65_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEI8448756.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(3346..3789)
                     /gene="rplM"
                     /locus_tag="SLE65_001457"
     CDS             complement(3346..3789)
                     /gene="rplM"
                     /locus_tag="SLE65_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEI8448757.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(4308..4775)
                     /locus_tag="SLE65_001458"
     CDS             complement(4308..4775)
                     /locus_tag="SLE65_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEI8448758.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(4895..6433)
                     /locus_tag="SLE65_001459"
     CDS             complement(4895..6433)
                     /locus_tag="SLE65_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HEI8448759.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            6513..7199
                     /locus_tag="SLE65_001460"
     CDS             6513..7199
                     /locus_tag="SLE65_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEI8448760.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(7400..7927)
                     /gene="msrA"
                     /locus_tag="SLE65_001461"
     CDS             complement(7400..7927)
                     /gene="msrA"
                     /locus_tag="SLE65_001461"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEI8448761.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(8011..8688)
                     /gene="pgmB"
                     /locus_tag="SLE65_001462"
     CDS             complement(8011..8688)
                     /gene="pgmB"
                     /locus_tag="SLE65_001462"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HEI8448762.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(8685..9815)
                     /locus_tag="SLE65_001463"
     CDS             complement(8685..9815)
                     /locus_tag="SLE65_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEI8448763.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(9815..11998)
                     /locus_tag="SLE65_001464"
     CDS             complement(9815..11998)
                     /locus_tag="SLE65_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HEI8448764.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(11995..13020)
                     /locus_tag="SLE65_001465"
     CDS             complement(11995..13020)
                     /locus_tag="SLE65_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEI8448765.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(13065..13892)
                     /locus_tag="SLE65_001466"
     CDS             complement(13065..13892)
                     /locus_tag="SLE65_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HEI8448766.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(13889..14956)
                     /locus_tag="SLE65_001467"
     CDS             complement(13889..14956)
                     /locus_tag="SLE65_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HEI8448767.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(14982..15818)
                     /locus_tag="SLE65_001468"
     CDS             complement(14982..15818)
                     /locus_tag="SLE65_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEI8448768.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(15815..16684)
                     /locus_tag="SLE65_001469"
     CDS             complement(15815..16684)
                     /locus_tag="SLE65_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8448769.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(16754..18037)
                     /locus_tag="SLE65_001470"
     CDS             complement(16754..18037)
                     /locus_tag="SLE65_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEI8448770.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(18051..19736)
                     /locus_tag="SLE65_001471"
     CDS             complement(18051..19736)
                     /locus_tag="SLE65_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HEI8448771.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            20011..21036
                     /locus_tag="SLE65_001472"
     CDS             20011..21036
                     /locus_tag="SLE65_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8448772.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(21631..25305)
                     /gene="rpoC"
                     /locus_tag="SLE65_001473"
     CDS             complement(21631..25305)
                     /gene="rpoC"
                     /locus_tag="SLE65_001473"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEI8448773.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(25363..28980)
                     /gene="rpoB"
                     /locus_tag="SLE65_001474"
     CDS             complement(25363..28980)
                     /gene="rpoB"
                     /locus_tag="SLE65_001474"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEI8448774.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            29708..30676
                     /locus_tag="SLE65_001475"
     CDS             29708..30676
                     /locus_tag="SLE65_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEI8448775.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            30694..31599
                     /locus_tag="SLE65_001476"
     CDS             30694..31599
                     /locus_tag="SLE65_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8448776.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            31596..32402
                     /locus_tag="SLE65_001477"
     CDS             31596..32402
                     /locus_tag="SLE65_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8448777.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            32538..33527
                     /locus_tag="SLE65_001478"
     CDS             32538..33527
                     /locus_tag="SLE65_001478"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HEI8448778.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(33844..34368)
                     /locus_tag="SLE65_001479"
     CDS             complement(33844..34368)
                     /locus_tag="SLE65_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HEI8448779.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            34655..>35876
                     /gene="scm"
                     /locus_tag="SLE65_001480"
     CDS             34655..>35876
                     /gene="scm"
                     /locus_tag="SLE65_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HEI8448780.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSD"
BASE COUNT        10328 a         7584 c         6638 g        11326 t
ORIGIN      
        1 aataaatata gtatctccat aggctttttt taaattctct tcattaaata cagattctac
       61 acttccgtga gcaattagat ttcgattcaa aagaataata ttatcaaaat acttctttac
      121 cttgcttaaa tcatgatgca caattagcac tgtttttccc tgatgtttca attcttttaa
      181 cgtatccata attattcgtt cactaactaa gtctatccct acaaatggtt catctaaaaa
      241 tatgaaatcc gcattttgag caagacatct tgctaaaagt acacgttgaa attgtcctcc
      301 agataattct cctatttgat gattagaata ttttcccata tcgacctttt ccaaagcctt
      361 tgaaactctt tgccattctg catttttaat tctttgaaaa actttcattc cggcatatgt
      421 tcccatagat acacattctt ttacttttat tggaaaagta aaatcaatat cagctttttg
      481 ctctacatat gcaatcttca ccagtttttt attgatatct tcattattaa tggagacctc
      541 tccctgatga gggataatat ttaacattgc tttaagcaat gtagattttc cagcaccatt
      601 tggaccaata atacctgtta aagcaccttc ttgtattttt aaagaaatct cgttcaatgc
      661 taaaaaatcg ttataacaaa cattaagctt tttcacttct aacataactt tctccttcta
      721 aatgataatg attatcacga tcatatggta tacaaaaatt atattttagt caaccctaaa
      781 ttttataatt tagatttttt tctgttgctg aagattagaa tgacaaaact atttgaaact
      841 acgcgtatag taagtagctt tcaaaatata taaaaaagga gcgttctcaa atgagaacat
      901 gctcctaaaa ctactttatt ggcgtatgga aaaattatac ttaaagtgga tagcgggttg
      961 aataagttga taagcatcaa aacatttata aaaattattc aagactatgt ctgttccata
     1021 tacaaatatg aaaatcagta aactccattt aacttttttc gtagtgtgtc tttttataca
     1081 tgtttatcgt tattaatagt gaataggaaa aaacctattt ttgatcattg acaattaaat
     1141 acaatttttg aataacgatc cctgctattc gagctagaaa ctcaagtacg ccatgacctg
     1201 attagcgaca aatacttaga gatttctttt tgttctggga aaacaaaatg ccatgacaat
     1261 agcagcaaat aatgatactt ccgtaaggct cgccgtaaac tggggagagg tgaaattcct
     1321 atgtgcttac ccaaagcaat tcaaaaattc taatcttttt taggagatga ttttataaaa
     1381 ttgagagtct acttgaataa aaaacaaacc tgtgagtttc taggaattga taataatact
     1441 ttagataagt ggattcgtat atataatttt ccagtaatca gaattgacgg tatagttcgc
     1501 tttgacatag aggatatcaa agattttatg aatacattta aaacaatttg aaaatttctt
     1561 ctcgccgcat atactaagaa tagcgaaata tactgcctta ctttttaagg gagtgaggaa
     1621 ttttgcctac aaaactttca aatgggaaat ataaaactaa tctgaggtat ccaaaaaaat
     1681 tcagagaaat cactggaatt acatcagaaa agtatcaaaa agtatttcca actaggcaat
     1741 tggctattaa agccgaaaat gcaatgaaaa ggaaaattga aacagtttta agagaggaga
     1801 atgcaaattc actagaatta aaaggaaaaa taaaatttaa ggaattctat gaatcaaaat
     1861 ggcttcctag atatgaacta ggtcagacta ctagatcaaa aagagctcca agttacgtaa
     1921 caattagtaa tactaaagat atattccgat tgcacatcct tccaatgttt ggtgagtatg
     1981 caatgaacta tctaaattca aatactgaga taatatcaga tgaattaaca aaaaaatcga
     2041 aagaatacgc aaatataaaa attatcaaag gatatgtccg ttctatgttt gatattgcag
     2101 aaatactaaa ttatattgaa tttaaccgaa ctaccaaaat tattcaatgt atcactgcac
     2161 ctaaaaaaat tgctttagaa gaaagaagga tacgggaagg taatcaagca ttatcgtcag
     2221 aagagcttat tgcttggata gaagcagtaa acactgactt gaataatcac ttgcttactc
     2281 ttcatgacta tactcttttc atgcttaccc tatatcttgg tgatagaaaa agtgagacgt
     2341 atgctttgca atggaaatat atcgactttg agaaacaaac ggttcgcctt aaacatgctt
     2401 tggataaata tcaaaaaaag aaatttacaa aaggtcgaaa ggataccgta attcaagtac
     2461 ccgaaattgt aatggcatta ctaagcaaat ggaaatcagt gcaagctgag caattgttga
     2521 gattaaaaat taatcaaaca ccagatcagt atctctttac ctatactaaa ccatccggag
     2581 aagtaaattg ccctgttcac gctgattacc taaactatcg aatcaattca attaaaagac
     2641 gacatcctga attggctcat ttatctccac ataagcttcg tcatacctat gcaactatag
     2701 ctagacaagg cggagcaaat atgaatcaaa tatctagtgc tttaacacac tcagatattt
     2761 ctacaacgag aatatacgta aatacaccag atgtagtaga taaaactgtt tttgaagcct
     2821 ttcagagagg attgaataaa tgtgattagt atgtgttctt aaatgtgttc ttaaacaaga
     2881 aaaagacact tttcaaacaa ttgaaaagtg ccttgaaaca ttgatatata aataatatta
     2941 acgtttagag aattgagatg ctttacgagc ctttttgaga cctggttttt tacgttcgac
     3001 catacgtgcg tcacgagtaa gtaagccagc acgtttaaga gctaaacgga agtcaggatc
     3061 aacttctagc aatgcacgag cgataccatg acggatagct cctgattgtc cagcgtatcc
     3121 tccgccgttt acgttaacaa atacgtcata tgcgcctttt gtttcagtaa cagcgaaagg
     3181 ttgattgatt acttcacgca agtcagcatg tggaatgtat tcttcaacat cttttttatt
     3241 tacagtaatt ttgccagttc ctggtactag acgtacgcga gcaactgcgt ttttacgacg
     3301 gcctgtgccg atatattgaa cttgtgccaa tgaaattccc tcctattaga ttaagtttgt
     3361 gatgtctaaa acttctggtt gttgtgctgc atgtggatgt tctgctccac cgtatacgtt
     3421 caattttgta aattgtttgc ggcctaaagt gtttttagga agcatacctt ttacagaagt
     3481 ttcgatcaaa cgacgagaat ttttagcacg caattcgcca gcagtgattg atttcaatcc
     3541 tcctgggtag ttgctgtgac ggtaataaat tttgtcagtc gcttttttac ctgttaattt
     3601 cactttgtct gcattgatga cgatgacgaa atcaccagta tccaaatgag gtgtgaaagt
     3661 tggtttattt ttaccacgta gtacagatgc aacaactgtt gaaagacgtc ccaatggaac
     3721 atcagttgcg tctactacat accatttacg ttctacttcg cctggtttgg ccatatatgt
     3781 tgtacgcacg ttattttcct ccaatttaag ttctgatgtt tgacatacac ttcgagtttc
     3841 cggggctctt tgtggggcaa acaataccat ttaacatatt acccgctaat ctagtcaatg
     3901 tcaacgtttt tctgcttgat tgaaaaattt atatgaaact ttacttcttt tctttctttt
     3961 atataaaagg gtcgtttcct gtcaaaatga aaaacaaaaa gaggctgtga caaaagtctt
     4021 gtcacaaccc cttattttga ataaacggtg ttctcctgcc aactcctcgg tcacaagtca
     4081 caatatccat aaaacataag aagctgtttt ttaaaattgt ttcttgtgac tcggagctga
     4141 acggcaggct tacaacctct tggtaaacgg tgttcaatca gctgaccctc ggtattagct
     4201 caaaaaacgg caaaatatga ggaactattt tgacgtttgt ttctctaata ctcaggtcaa
     4261 aacgctgatt tcacaacctc tttttcggtc aagttcaaca acagttttta cgcgtcgatc
     4321 tctggcgctt tgcccaaatg agcttggatc atccagatac gtttttctgt ggctgttttg
     4381 aattcgataa agatatcttg tgttggatcg tcgccttctt ctccagaaac ttcgattcct
     4441 ttttggtaaa gatctgctag ataacgatag cctgcaacaa gtgtttccaa acgttctgga
     4501 atagtacgat cccagcggcc aatttcatca gggatttttg tgttatctgc aaattcacgc
     4561 aatgtagaat aaggtgaacc gtctaatgtg atcaagcgtt cggatacttc atctaactga
     4621 gcgttcaaat catccatgaa ctcatccatc attgggtgca atgtaaggaa acctggtcct
     4681 ctcatgtacc aatgtgtttg gtgaacaaca acagacattt ggcttagatc tgcaactaat
     4741 tgatttaata cttctttggt ttgttggaat ttcatctttc ttgcctccta acattttctt
     4801 acacttaaaa taatagtaga ctttcaatga aaagtacaac aaaatcattt acctgagaac
     4861 gattttcagt tcgctttttt atccgtaaag ccaatcattt ttcagaatca gctaattctt
     4921 ctcgcagttg agcaaattgc tgataagtct gtgctaaatg cttttgtgtc gaaacaaata
     4981 atggatagat tttctgatat tttttatgat cagtttcttg tactccaact tgctctttca
     5041 attctatcaa ttcctgtgct tcactgatac tttggatctt tccgatgctt ctccagccta
     5101 aaatcacagc tcctaatgcg gatgcttctg tgacagtagg gaaaacaagc gggtaaccca
     5161 gtacatcagc catcatctga cgaaaaatcg gagattgagc aaacccgcct gtagcacgga
     5221 tctctgtgag ctgattttcc tggcaaactc cttttaaaat ccgataaagg ttgagacaga
     5281 tcccttctag aatcgccttc atcatttctt tttctgtatg ttgccgctgt aaaccgataa
     5341 aactgccaaa cgcatctgcg tcccaaagcg gtgctcgctc accaagtaaa tagggatgaa
     5401 aaatcagacc attggcaccc gctggcacaa aagcgatagc cgaaagcagt gcatcatatg
     5461 gattttctcc tttttcttta gcagattgaa cgacttcctg taaaaatgta tgccctgccc
     5521 aatcaaagat gccagcacca ttgctagtcg ctcctcccac tacccaatgt ttctgatcca
     5581 gaacataaca aaacgtctcc atttctggat ggaactgagg ctgagtagta ataaaacgaa
     5641 gtgctccgct cgttcctacg gtcaaagcgg cgatcgtatc accaaaagca cctaacccta
     5701 gattagaaag cggcccgtct gcccctccca aaacaaatga tatatcattt ggcaaaccta
     5761 gttctgctgc tgtttttgat ggtagacctg ttacttgata ggtggaagga aagacttgcg
     5821 gcaattgctc tattcgaatg ttcaagtagt caagcacttc ttctgcccat tggaattcat
     5881 ggatatcaaa atatccagtt cctgaagctg ttccgtagtc gctgatcagt tcgccaaaca
     5941 atctataaaa gatatagtct ttgataccga caaaataagc agtttttttg aataattcag
     6001 gttggctgtt ttgcagccac ttgattttgt tcaatggtgt cattggatga atcggcgtcc
     6061 cagtctgccg ataaaattct ttgccaagca cggtatattt cagtttttct gcttcgtccg
     6121 ctgctcggtt atctgcccaa gtgatcattc gagataacgg tgttttctct tcatccaaca
     6181 atatcaggcc atgcatcgca gaggagaagg agacaaattg aatgattgtg tctgaaggca
     6241 actgtttaat tacttctttt ataacggtgc agacaccttg aaagatcaat tcctgatctt
     6301 gttctgccat cccttgtgtt tcttggatca aagggtagcg aaaataagcg gatgctgctt
     6361 cttgggcttc atctgtgaaa gcaactgctt tggtttgtgt ggttccgata tctaatccga
     6421 ttgaaacgtt cattttttca cctcaaattt tatgtatgta caaaaattta gtttaagctt
     6481 gcgtatcttg gttttgaaaa gggggagatg gcgtgttact ttattttatc attggttgct
     6541 gtatcggatc atttttatgt ttaaccgccc agcggattcc gttaggtcac tctattattt
     6601 atcctagatc tcattgtgtc aaatgctgtc gttcgctttc ttggtatgaa ttgattccga
     6661 ttctctcgat catcgtccaa cgatttcgct gccgctattg caggtgtcgg ttgcccttct
     6721 actatttgtt ggcagaagcc ttatgtggtg gtctttttgc ctggttcttt actttttctt
     6781 ccgcaagaaa tttttcgacg ttcatatgga tgctttcggc tttgctattt tcgttgatgg
     6841 atttatttta cttcatggtc cattctcaca cgctattctg ttcttgggca attttatgga
     6901 ttttttggtt gcaggccggc gtcttccaat ggcaaagtgt gctgttaacg tttatcgtag
     6961 gcggtgtgtg ccttcgctat ggtcaatcct atctcggagc tggcgatact ctgttgatgc
     7021 tttcttggag tggtggcttg tctctagaag agttgcttca gatcttgttt cttgctagtc
     7081 tgtttggaat atccgttttt tctgtttact ttatctgtca taaaaaaaag ttggaaaagc
     7141 tgcctttcat tccttttttg agcagtgcgt tgctgattgt ccttcatctt aggtattgaa
     7201 aaaaggttgt gacaaacgac ttgtcacaac ctctgatata tagtgttctc ttaccaaatc
     7261 cttgtgactt ggagctaggc gacaggttca caacctctcc actaaatggt gttcaatcag
     7321 ctgaccctca gtattagctc aaaatgctgg ttttacaacc tctgatatac ggtgttccat
     7381 aagtagcttt ttcggcttct tatttcttga cgccccaatg tcgacgaagg aaacctgcac
     7441 gtccagaacc ttctcgataa agattgtaat ggagcttgtt tttcttgtaa taatcctgat
     7501 ggtaatcttc tgcaggataa aattcgcttc ttggttcgat ttttgtcacg attggcttat
     7561 cgaatcgccc gctgtcttgc aatgcttgtt ttgaacgctc tgcaatattt cgttcttctt
     7621 catcattata gtagatcact ggacgataag aatcaccgcg atcagcgaac tgtcctaatg
     7681 cgtcagtcgg atcggtttgc tgccaataga tttccaccaa ctgatcataa gaaataactt
     7741 ctggatcata ttcgatctct actgcttctg tatgccctgt tgtgcctgtt gttacttgtt
     7801 cataagttgg atttggtaca tgcccgccag tataaccgga tgtcacagaa atgatccctg
     7861 gctgctcttc aaatggtttg accatacacc aaaagcatcc gcctgcgaaa actgcttttt
     7921 ttgtcatata aaatccccct tttttctcat cataccttga tttccaaaag gaggataacg
     7981 ttttgcttgt gacagaaaaa acggaaacta ttatatacgt gatacggctt ctgataaatg
     8041 ccaaaacgaa cgtacttgat caaaaacggt taaatcagga atcacatatt cagcagaagg
     8101 aagatttatg ttttcaccta ttcccaatac atgcatgtta ccagccaaag ctgcttgaca
     8161 accagcttct gaatcttcaa tgaccaagca tgcatttggc ggtacattca attgctgtgc
     8221 tcctttgaga aaaacttctg gatcaggttt tgcttttgat acttgcgtgc cgtcaataag
     8281 gacatcaaaa taacttgtca aattcgtttt ttctaaaatg aggcgtgcat ttttgcttgc
     8341 tgatcccaat ccgatcttga tgtttgtttt tttcaagtac tcaagaacag ctattgcacc
     8401 aggcaaaacg gatgtttcat ccattttttg aatcgcttga agatatagat tgtttttttg
     8461 ctcagcaaag gctgatttct ctttttctga gaatttctgt tccatttttc caaatgacag
     8521 caatcgctct agtgactcgg ttctggatat tcctttcagt tgctcgtttt ctttctcagt
     8581 gaatggaatg gacagctggt tagctaaaac cagccacgct tcgtaatgat aacgagctgt
     8641 gtctacaaga acgccatcta aatcgaatag tgctgctttg attttcatcg attacctcct
     8701 tgaaaatgaa cgacttgaag taaagatgcg atgtttttag ctgtgcgatg aagattatca
     8761 gtggcttgct gtaaagcttc ttgtaaaggc acagctgcag gaaggatcgg aaaaacggcc
     8821 gaaatgccaa catctgctgc tttttcgctt cctttaccaa cacttccgca aatagctatc
     8881 acaggaacgc cctctggtac tcttctagca atcccaactg gcgcttttcc ttttagactt
     8941 tgtccatcta gacgtccttc gcctacgatt acgaggtctg cttgctgtac ccgtttatcg
     9001 aactccagta aatccaatac gtagtcgatg ccagagacta ttttccctga agcaaatgct
     9061 aacagtcctg cacccattcc accaccagca ctactgcccg atgcctcgat tacttgaggg
     9121 gcaaatctca tataaaaatc atgcatggct tggtcagcca ctgctaattc attttctttc
     9181 aagccttttt gtggtccgaa aacaaaagaa gcgccttctt ttccgcataa aagattagta
     9241 acatcagtaa tgacagtgat tttggcttta atcagctcaa taggcacgtt cgttttatca
     9301 actgtagcaa ttttacctag attttctccc agtgcttcta ctttttgatt atcttgatcg
     9361 taaaaagcat aacctagacc ttctgccatg ccgatgccgc catcgttggt actacttccg
     9421 ccaacgccga tgatgatgtg tcgaacacct tgttgcaaca attgtcgtat cagttctcct
     9481 actcctcgcg tggataacct aagtggctgt tgttggttta gtgggacatc tttcaatccg
     9541 acgatttctg ccatttcaaa aatcgcagtt tgaccgtctg aagcgtactg gatttctttg
     9601 tttttgccaa atgcattagt aacgactgct gtttgccgct tcaaccttaa actgtctgct
     9661 aatgatgaaa ccgttccttc tcctccatcg cctataggta gcagatcata ttcagcctga
     9721 acaaaaactt cttgaaaacc tgattgaatg gcttgtgctg cctctaaggc tgtcagactt
     9781 tctttgaaag aatctggcgc aatcagaata cgcattattt tcccctccgt tccaagatca
     9841 gttctttttc cagctggtat tggtctccat tgacaaaaat aggtaatgtt tctttcgtct
     9901 ctttttttat tactatttgt ttttttgtca aaacaaatag caacctgtga tttttccaaa
     9961 taaaaggaaa agaaattttt tcccatgctg aaggaagtct tggagaaata gaaagagttc
    10021 cattcgttac tgtaatacct gaaaaaccaa atataactgc tagccatagt gctcctaatg
    10081 aagcagcatg aattccgtca tctgatgaat gcggatctgg tcctaaatca atcaggcacg
    10141 cttcttggaa taaatgatac gcccattcca tttcttggat acggcaagcc tctatggcgt
    10201 gaatcgcttt actcaacgat gagtcgtgga ttgttttgtt ttcatagtaa tgcaaattct
    10261 tagaaacgat tggttgagaa aaatactcag gtaataagta taacagcatg acaagatctg
    10321 cttgcttgct gacttggagt tcatttactt cgctacgggc ataatcaagt aaaatagact
    10381 ggctgccagg acgttctttg taagtggtca aatcaataac tggcttactg agatacgtgt
    10441 catcttgcgg aatcagctgt tctttgttag gcactggcaa atataactta tctaaaaaat
    10501 tttgacattc tttcaaaaaa agcggatcgc cagcttgata tttaacagct aaggccacat
    10561 tataatgcgc cagatagttc gtatatgcat tattgtcgat atattctgtg tattcatctg
    10621 gaccaatgac tctgtgtatc tctaaatgat catcgacttt tacagctctg ctcagccaaa
    10681 aagctgctgt ttcatgaatg agcgtttttc cctttgtttc taaaaacgat tgatcctctg
    10741 ttgcttggac atactcttga acggcataag caaggtctgc actgatatga tgttctgcgg
    10801 cagctgaagc aacttcttgt cttgttccgg ttttgatatt caatgcagca aatttgggtg
    10861 tctcttcctg accagtgtgt gcgctttccc atgggaaaag tgcaccttga tagtgataat
    10921 ctcttgcttt ttgccgtgcg ccttctaatc gatcataacg gtacagcagc aaattctttg
    10981 ctacttcagg aaactgatat aaaaagaaag gcaggataaa aatttccgta tcccagaaaa
    11041 catgcccttt ataaccttcg ccagttagtc ccttcgcccc tacactaaca cttggatcat
    11101 tgcggggagt cataatctgt aaatggtaag cagcgaagtc catcgctaac tgatcgaaag
    11161 aagaatcgcc ttggatcgtt atccgatgct gatgccaaaa atctgtccaa taagacatcg
    11221 actgctctaa aatttctgta taactaacgc ttttctgggc ttgggcaata cttttcttaa
    11281 acgggtctgt ttgctgaaga gaggtagaga gcacgatgat cttctccagc gtaaaggacg
    11341 tattttttct gatcttttct gaaaaggaag cggtgatccg gcgatttttt gcttggaata
    11401 cacctgcttt attgaattta gctgcaatcc caatatcaat tttactttct gttgtctggt
    11461 aggatgcact gatcaaatcg tcaccaaata ctcgcagttc tttttcaacc aactgctgtg
    11521 taccaaaatt ggtttgctgt ccatcgatac ccgttttcac atctacttgg cagtcttcgg
    11581 tcaacggctt gatgaccact ttcagggctg cctgatggag attattttga tcagcaacac
    11641 gacaagtaat gacttccact ttttttcctt gagcagtttc aatgagcgca tagcgtttaa
    11701 gctctcccat ttctaaatct agtgcccgct cgtatgcaag aactttcatc gtctcaagag
    11761 aaaaatgttc accgtcgatt tttatttccc atctgatgac atctgggaga ttcactaact
    11821 cggctgattc tgctcctaaa ggtcggttat atacaccagc tgcaaacatt ccccttactt
    11881 gattccgata gtcttcctcc tggcttcctc tgataccaaa aaatccattt ccaatggtca
    11941 tctgactcgc atacttattg atatactcta aatcaaactg tttttcttct actttcataa
    12001 ggtaataact tctcctgttt ctgccgaacg atataaattt tccaccagat tctggatgac
    12061 atatccttgc cagccatctg caatcatctg agtctggtca ccgagcgccc gattcacaaa
    12121 atgagccata cttagttcat gtgggtcatt aactggcgtg gtcttttgta aggaaaccag
    12181 ctttccatct acatcttcga atagttcgcc tggatacaga ttagcacctg cctgatcgcc
    12241 acaaaaagcc acattcagtt tgtcttctct gatattcaaa gcaaacgaag tattcagttg
    12301 gatgatcttg ccgttttcta attccagtgt gccaaaaatt gcatcttcta ctgtgaattt
    12361 gcttggatcc catttcccga atttccctga attttttttc gtaccaattt tttggaagct
    12421 gtacgcccga acgcttttta ctttaggaaa tccagtaata tacatcgctg tatcaagcat
    12481 gtgaatgcca taatcgatca aaggcccgcc tccttgaagt tctttgtcga taaacgttcc
    12541 ccagcctgga acaccagacc gacgaagcgc attcgcttct acgtaataaa tatccccgag
    12601 aacatcaaga tgattcttga tcattgttgc ttcgtcagaa aaacgatgct ggaatccata
    12661 agccaaaatc tgcccgtttt tatcggctgt ctctgccatc tttcttgctt gatcagctgt
    12721 catagctggt ggtttctcgc acatcactga agcattagct tcgagggcag ccaatacatg
    12781 ttcgaagtga aagcgattgg gtgtacagac actcacgata tcgggagaaa tctcattcag
    12841 catttgtgta actgatgtat acgcatgaga aaatcctgta cgtcggcaaa agtcttctgc
    12901 tcgctggctg actggatcaa ccacagcggc caattctaag acatctgatc ttttttgata
    12961 ataagcagca tgtacttttt ctgctacttg tccagcgcct atgattgcta ctttcttcat
    13021 ttatttctct ctcctttgct tatttactta ttgttattct ttctctattc tttctctaaa
    13081 tcatttaaat gacgcgctgt ttccagacag tttttcaagt attgcaatga ttcctgataa
    13141 attttcactt cattttctcc tcgcaaacga cattcatata ccatataacc ttcatactca
    13201 ttttgaagta gcgtttgaaa atggcgagta aaatcaattg cgccagatcc tggttggtag
    13261 cgatgattat ctgctaaatg gatatgaccc acatactctt tttgcgtagt caatgctttt
    13321 gaaatatcat cttcttcaat attcatatga taaaaatcag cgatgatctg cacatgtttc
    13381 aattgattag agtcaatgta atgacgcgca tccgctaaca aattgatcat atggtcttgg
    13441 tatcggttca aaggctccaa ataaataacc gtacctgttt cttcggctac tttatctaaa
    13501 taacgaagtg attcgctgac tgctttatag tctccttctt tgcttcgggg tgaaaccatc
    13561 ggcggtaatc gataagtgaa cattccccaa gctgctggga taacgattcc tttgcctcca
    13621 acctcgctta gtgcacgcaa aatctcagca atttgacgta caccattaag acgccgttct
    13681 tcgataaagt caccgatcca cccatcgtag ccgttacaag ctgtcactac tgggatccct
    13741 gtttctttga ttgcctgttt gactgtgtcg atattttcta ttaacaactt accgtcgatt
    13801 tcgtattctt caaatccaca gtctttgata aatctaaatt tttctaaaat gtctcttggg
    13861 aaaaatgctt gatcttgcgt accgaatttc attgttctcc tcctcggact tgaacgccca
    13921 ttttgatact ttcttctggg tgctggtcta cataacgcat gtaagcttct gcgctttctg
    13981 caaatggcac aactggatca atgatttctt cacaatccaa gtaaccgttc atcaataatt
    14041 cccaacatgt gtcctcgatt cgtttacggt tccatcttgg gtaatctggg tttggttcac
    14101 tagatgctcg agcaaagacg atttttgcat tattgaaatg tgcttcgcga ccaagattaa
    14161 acccagctgg aaaaggttta gcaaaggcaa cataagaaat gatcccgcca tagccgatcc
    14221 ctcttaaaga agcttgtaat gcggcagcac tgccactcgt ttcaataact gaatctactc
    14281 cacgtttatc tgtcaattcc tttagacgaa aaccgacatc tgctttcata ggatctagcg
    14341 tgtaatcggc accgtatttt tctgctaatt ctctacgctg cgctatggga tcgatcccaa
    14401 cgatggtagt agcacctgct tttttagcta attgaatcgc aatttgcccg atagcgccta
    14461 aaccgaagat tgctacagca tcacctgctc gaacatgtgc ttcccggata ccacctaaag
    14521 cgaattgagc aggatcgtaa catactgcat ttttccattg atccaaccga tcaagtttac
    14581 gtagtttata attatcaaca ccgtttgtaa tcagcgtttc acgaatgggt ccataagtgc
    14641 agactaactc tcctttttga tactctgtca ccaaactgcc cgtttcttcg atcgtaccga
    14701 caatcatatt tcctaattga aattcgccaa ataccacacc gcgttggctt ccttcttctc
    14761 ttggcaagaa taggcgccat tcttctgaaa attcttcatc gataaatgga cttaatcctc
    14821 taaagtcgac aatttctgtt cctggttttg gagtagcgaa aattactcgg atacgtactt
    14881 cgttcttttc gatctcacgg tcttcgtaat ctttgaatcc ggctattctt ggttctaatg
    14941 caactaattt tttcatcttt tctttcctct ttcttttctt tttatccttt tacgccgcct
    15001 tcgactaaat cacctttaat aaatcgttca gataacgcat acataatgat gactggtaaa
    15061 gcggtcacca atgaagcggc catcattcgt ccccaaatgt agtctggtgt actgaataat
    15121 gtgttcaaac cgattggtaa agtaaatttt tcggaggtcg acaggaaaat cgaagcaaat
    15181 aaataatcat tccacgaaac cataaagcaa taaacgaaga cagaaatgat tccagaaata
    15241 gccaatggta taatgatccg aataatgatc tggatccggc taagaccatc gatcattgct
    15301 gcttcttcaa tatcagtcgg aatcgtgtca aaataacttt ttagcatgaa tatcgcagta
    15361 ggaagtgttt gaacgaccat cgtgataatc agtgctgtat tggtatcata caaacctaga
    15421 ccggaaatga ttttaaataa tggaacaacg atcaaaatac cggaaaacat ataaacggtg
    15481 taaaagctag cattgatttt cgagcgagct ttgaagcgta gttttgacaa agcgtatgcc
    15541 ccgctgatcc caatcactac tgcagttacg gaggctatca aggagatcac taaactattt
    15601 ttgaaataca tgatgaatgg aaaaatctca gcattgaaaa tatcctgata atgttcaaaa
    15661 gtccattctt tcggaaaaat agtttgtgtc gttgcaattg cttcttgtga atccttgaat
    15721 gatgtcatca gcatgatcaa aaatggaaac aaattgacag ctaatagcaa caaaatcgtc
    15781 gcgtaaaata agattttcct gctcttttta tttttcattt caagtccacc ttctttcgtg
    15841 agagcaagac gaccgctgca ataatgatga acaatagaat cgatatagct gctgcttttc
    15901 caagatcatt gaacgcaaag gctgtctgat acaaataaac gcctaagata ttgactttat
    15961 tcgtcagtag atagacatct gtaaacatat agaacatcca gatagatcgt aaaacaatca
    16021 cagttgctag tactggtttg attgccggca gtgtcacgat cttgaacttc tgccaagcat
    16081 ttgcaccgtc catttcagct gcttcataaa gcgttttgtc gactgtttgc aaaatagcca
    16141 aaaatgaaat aaacgcatac ggatagtatc tccagatagc aaacaaaacg accataaaga
    16201 agctagcaac tggctggtcg aaccacagcg gtgcttcgtt gaaaagctgc aacctatcta
    16261 ctaacagatc attgacgatt ccataactat tattgaacat atatttccaa gcaaaaatca
    16321 aagaaataga tggcgtaaca taacttaata aaatcagtga acgcaccgtt ttcctaaatc
    16381 tgaacttgcg gttaagcaaa atagctacgg ctaatcctaa agctgtactg cctgctacaa
    16441 ctaagaatgt gtaagcaact gttaaaccta aagaacgata aaattcacta tcacttaaaa
    16501 tttcaagata attgcttaat ccgataaaaa cggcgtctga gttaggattc agcggcatat
    16561 cgaaaaaact gatctgaata ttggaaagca ttggaatcag cactaaaaca gctaataaaa
    16621 gcatgcttgg tgctaaaagt cccatggcta attttaagtc agaatgtttc cttggacgat
    16681 tcattgaaac ctccccctga taatctgcca atagctatct acttttttcg aacaccattg
    16741 gcagaacttc ttgttatttc gtattttttt gtgcgtcagc taaagcttga tcgacatctt
    16801 cgtttccgac agttacttgg ttcactgctt ttccgatcac acctgagctt gtgatatctc
    16861 ccattttcgt gaaattcttt tccccgacta gtccaaagac ttgtacttca tcaaaagcac
    16921 tagcaatctc agatggcagc tcgccaaaag acttgatgac ttcattttct ttgtaaccat
    16981 ccagttcgac tacttgttta ttcactggtt gagcaccacc aggagacatc aagacccact
    17041 tttccatgtt tttcggttga gataagaaag ctgtgaatgc ttcagcagcc tctttttgtt
    17101 tctcgtctag accagaagaa atcgtcaatc cagatactgt gccatagaca gcttgatctt
    17161 tttgtgttgg gatagcaaaa ccgatatttt ctgagttccc cgcttcataa acagaaggca
    17221 aaatgtaagt tgaatagatt gccattggtg ctgttccatt catgaaagca tctttgattt
    17281 ctgtcacatc attagagcct ggcatcgtgt attgggataa gttttgataa aacgacaatg
    17341 cttctctcat cttttccgta tcgatcgtta cctcgccttc atcatccaaa acatttgctc
    17401 catttgacaa agcaaattga gagaacgctt gctcactcat tgttccttca gcagtaggca
    17461 tagcaattcc atattgttta ttctctttat ctgtgaaatg ttgagcaatt tttaaaatat
    17521 catcccaatt ttctggttct gaaaaaccag cttctgataa tttttctttg tcataccaaa
    17581 taccttgaac ccagccgcta attggtgcag caatatagct ttttccatct tctgaacgaa
    17641 caaggttttt ggctccgtca taataattat cttctccagc ttcctcgata acgttttgga
    17701 ctgccgtctg atcaatcagt tcatctttat ccatcacttt agcaaaatcc tgactgactt
    17761 ccattacttc tggtaattta ccggaacgag ctaacgtaac gatttttgta ttgaacgctg
    17821 attcttctac cggcacttgc ttgattttga tgtctggatt ttctttttca aaatcagcaa
    17881 ccagttcatt gatcacactt aatcgttcct gttcgacaga agagtgcatg aattgaatcg
    17941 ttgtctgttg tgattcgtta gagctttgac tttcaccaca agcagtaaga agaaatccag
    18001 tagctagcag acaggtagta acaataattt ttttcatttt tttccacctc ttattttatt
    18061 attttcagcc acatatattc atacggctgg aatatcaact ttcgttcttg actgcaatgg
    18121 ataatttgtc cagaaaacag gtctaggtaa tctccttttg gtaaaagata acctgctgat
    18181 tgattggaaa aattatggat aactaagact ttctcttcct tcgcttcgcg aataaaactg
    18241 ataaaagaat ctgctgagtc cagtaagtaa atcaaactat tcggatggaa ggctttttct
    18301 ttttttcgaa tagatagcat ctgggtcaat tcaccatata ctgctgttct taatggatct
    18361 gtctgcaact ctttctcaat atctgctaac aaaaattttt gccgattgat ttttcgattc
    18421 tctcctgttt tttctacgcc tttgtaatca tttcgacttc ccagcacact ttgaatataa
    18481 attgccggca cgcctggtaa cgttaccaaa aatgaatgag cagctaaaaa gcgtttgctt
    18541 ctccattccg tcgtatctgt tggagaactt aacgcatcta gatacgtagc gtttatctca
    18601 tatggactgg tcgttccatc tgggtttttc ttgtagttta ctcgggcacc ctctttcttc
    18661 agctgttcca ctaattcaag gatcgttttt tccggcagaa tacctcgtac cggattcaat
    18721 ccgataccgt catgggaggc taaaaaatta aaaaaagttg tttttttcga tgcgaaatcg
    18781 atggttttta accattcttt caacttactt gtattacccg aacgaatcgc ttgaagggtc
    18841 aaaggtggta gcgaaaactg atagaccatc tgtgcttcat tctcgccatt cccaaaataa
    18901 ctgatattat ctttgtgtgg cacatttgtc tcagtgatca ataccgttcc tggagctgct
    18961 tcatcagcga ttgcacggaa taattggatg attttatgcg tttctggcag gtgtatacaa
    19021 gaagttccta gttctttcca taaaaatccc acagcgtcca agcgaataaa tgaagcgcct
    19081 ttttctaagt aaaacaaaag aatatcgatc attttcaata aaacttctgg atttttaaaa
    19141 ttcaagtcta cttgatcttc gctaaaagtc gtccatacgt gtttttcttt cccgtttttg
    19201 tcaatgaacg ttgtaagtaa cgggctggtc cttggtctag tcacgctgct tgtatctgta
    19261 tccagtggca aatcaataaa aaaatctttg tacgtatcat tcaagtttaa atattcctga
    19321 aaccaagtac tttcggcaga catatgattg cagacaaagt cgaacattaa ccgtgtttcg
    19381 cttctcattt cttctatatc ttcccatgtg cccaaacggt cgttgattgc ctgataattt
    19441 acaacggaga aaccatcatc agatgtatat gggaaaaatg gcaagaaatg tacaactcta
    19501 aatgtatctg ccaaatactt ttgataaaat ttcttaaatg tacgcaaagt tggttgctgc
    19561 tcttcaaaaa attgatcccc ataagtaatc aagaaaatat cttcttcgtc ccaatgcagt
    19621 ttgcctgcct ggcctttctt ctgctgataa acactgactt tttgttcaat catagaggcg
    19681 gttttctcag acaaatctga gtcgcgataa atcgcttgta aaagttttgt atacatcgga
    19741 ttcccctttc ttttttggga gcgttcccaa cgatttgatc atattatgga aaacgcttac
    19801 tgtcaatagc atttttttaa ataattttga tatacacaaa aatacaaata agaaagctta
    19861 tgtatcaata attaatagct tcttaaaaaa atatggtctc tcatgatcat gcaagctatt
    19921 cctaaatttt caaaatcata gacaaaaaag aatgtctatt gtactatgga attattctaa
    19981 aacgctccca aaaaggaggt gcatataaaa ttgaaaccta ctatttatga cattgcgaaa
    20041 aaagctaatg tctcaaaatc aactgtctcc agagtattaa ataaccagcc aaatatctct
    20101 gataaagcaa aagcaagtgt acttcaagca atcaaagaat tgaattatga accgagcaaa
    20161 attgcaagag gactgtcagg aaatggtttt gacgcgattc tagcattatc tcatcgtact
    20221 tctcatacga cctatggcaa tccttttttt tcagatgtta ttcaatccat ttctgccgtt
    20281 tctgaacaaa ataacttcga cttgattcta caaacggcaa aaacaccaga agaagagcta
    20341 gaaaaatgcg cgaaaaagat ccaagaaaaa atgatccgag gaattattat tttaagctct
    20401 acgatggatg aaacacttct ttttgaattg gatcaataca atattcctat tgtggtaatc
    20461 ggaaaagtcg gaaacgacta cacgaacatc tactcagtgg acacggataa tttccaggat
    20521 agttacgatt tggtggaaac actgatcaag aatggacacc gtcatatcgg ctgtctccat
    20581 gctccgacag aagtttatgt atccaatgat cgtctcaatg gttaccgtca atgcttattt
    20641 gatcaccacc tagatatccg taatgaatgg attatagacg gcggctttcg cttagaagat
    20701 agcatggcag caatgaatga tttaatgaag ctacgagaaa gaccaactgc gattttttct
    20761 accgatgcat taaaatcatt gagtatttac aaagtggcag aacaatctgg aaagcagata
    20821 cctgatgatc tttcgatcgc aggattcagt gatcccttat tgtcctccct attttcgcca
    20881 cagttgactc ggatagacat tccgacaaat cagttaggaa tcaaagccac agaactttta
    20941 ttccaactaa tccaccacca ataccctgaa gaaaaaagaa tcattctttc aaccgagatt
    21001 actctcacag attcgatcca acaacaagaa atgtagaaca gaattataaa agaacagaaa
    21061 cactgaggat aagtcagtta ctctgttctt ttttcaatca ctcatccctc gttaccccct
    21121 cccggtattt tagcgaattt ttcttatttt ccatctgttt tagatagctg tggataacta
    21181 taatgtttgt gttaaactat tttttccaca gggaagaaaa aactattttt aaccacgttg
    21241 tgtataagtt tttatagttc gtttttttaa acacatttac ccttatttca atccatgtta
    21301 tttggggata cttatctcta aaacataaat agaataacag acatgtctac tggttttgtt
    21361 ttattcgagg aattattcaa taatagctag caaaatatta aaaataaccg ctctatcttc
    21421 ccatcaattt attttgcatt caaaaaatga tctatcttta cttttgttga ttgacttctc
    21481 ttggaagatg atcgttccga taccttaatt ggatacgaac cgatgttgtt aagatccttt
    21541 cccacttttc ttctagttag acaaattatt ttagacaaac caaaaaagag gttgtgacaa
    21601 taatttgtca caacctcttt tttaaaatat ctattttgtt tgattgttca ttgcgtcttc
    21661 tgcagccatt tgcgcttcaa tatctgaaat actgtagaca ttttcgcttg ctacaccgac
    21721 ttcttttggt tccatgtcac gataacgttg cataccagta ccagctggga tgatcttacc
    21781 tataataaca ttttctttca aaccaagaag aggatctttc ttaccgcgga tcgcagcatc
    21841 cgtcaagaca cgagttgttt cttggaatga tgcagcagat aagaaactat ttgtttctaa
    21901 tgatgctttt gtgataccta gtaagacagg tcgagaagtt gcaggaacgc ctcctgagac
    21961 tagcgtattg tagttttgat ctttaaagtc tgcgatgtct aataatgtac ctggtaagat
    22021 atctgtatca cctggatcca ttacacgaac tttacgcagc atttgacgaa ccattacttc
    22081 gatatgcttg tcgccgattt ctaccccttg catacggtaa acacgttgta cttcacgaag
    22141 caagtagttt tcaacagata atacatcgcg aacttgcaac aattgttttg gatcgattga
    22201 tccttctgtc aatggtgcac cacggtggat catatcgcct tctgctactt tcatacgtgc
    22261 tgtataagga acagtatacg tacgtgtatc tgtttttcct ttgattgtta cttctttggt
    22321 acgtgttgca ggatcttctg agatatcgat gacatcccct gttacttctg tgatcactgc
    22381 ttgccctttc ggattacgtg cttcaaagat ttcttggaca cgaggaagac cttgagtgat
    22441 atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc gtcaactgag taccaggttc
    22501 accgattgat tgagcggcga tcgtaccaac tgcttctccg acttcaacgt cagagccagt
    22561 tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt tttgtattac atgtgaagac
    22621 agaacggatt gtcactgttt cgacacctgc atcaacgatt tgttttgcga tgtcttcgga
    22681 aatcaattgg tttcctgcaa tgatcaattc atttgtttca ggatgacgta cttctttacg
    22741 ggtgtaacgt cccactaaac gatcttctaa tgattcgatg atttcatttc cctcgcggat
    22801 ggcttggatt tcaagacctc ggtcagtacc gcaatcttct tcacggatga ttacatcttg
    22861 ggccacgtca accagacgac gagtcaagta acctgaatcg gcagtcttca aggctgtatc
    22921 ggtcatccct ttacgagccc cgtgagttga gataaacatt tccaagacgg atagtccttc
    22981 acggaagttc gaaatgattg gcaattccat gattcgacca ttaggagcgg ccatcaaacc
    23041 acgcattccg gcaagctgtg taaagttgga aatgttacca cgagctccag aatcagacat
    23101 catgaagatt ggatttttcg cttccaaacc ttccatcagt ttttgttgga tgctgtcttt
    23161 tgcagcattc caaacagcaa tgacacgttc ataacgttcg tcatctgtga tcagaccacg
    23221 acggaattgt tttgtaatag tttcaacttg tttatgggca ttttcaatga tttcttgttt
    23281 ttcattcagt acactgatgt cagcgatccc tactgtgata ccggcatgtg tcgaatgttt
    23341 gtaccctaag tctttcatac ggtcaagcat cttagaagtt tctgttactt tgaatcgttt
    23401 gaagacttct gcgatgatgt ttcctaagtt tttcttcttg aacggtaata ctaattcttg
    23461 ctctttgata tgtgcaggaa tatcagtacc agcttcaaca aagtatttgt ccggtgtttg
    23521 gacggtcaag ttgaagtctg ttggttcatt cagataaggg aattcaggag gcatgatctc
    23581 gttgaagatg atcttaccaa ctgttgtgat catcgtacgt tctttttgcc attcagtaaa
    23641 tggtttttca cctaatgagt tagggttcac accgatacgt gaatgtaaat gaacatatcc
    23701 gttgcgccat gcgataacgg cttcgttttg atctctgaag accattcctt cgccttcgcg
    23761 tccttcttct tccattgtca agtagtagtt acctagaacc atatcttgag aaggagtaac
    23821 aactggttta ccatctttag ggttcaagat gttttgagca gctaacatca acatacgtgc
    23881 ttctgcttgt gcttcttcat tcaatggaac gtggacagcc atttggtctc catcgaaatc
    23941 ggcattataa gcttcacata caagtggatg caaacggatt gcgcgtcctt gtactaaaac
    24001 tggttcgaat gcttggatac caagtcggtg aagcgtaggt gcccggttca gcaatactgg
    24061 gtgttccttg attacgtctt ctaaaacatc ccatacttcg tcttcttgac gttcgatttt
    24121 acgtttcgca tttttgatgt ttgaagctag ttcgcgttga acaagctcac gcatcacgaa
    24181 tggtttgaat aattcaatgg ccatttcttt tggaagtcca cattggtaca tcttcaagaa
    24241 aggtccaaca acgataacgg aacgacctga gtagtcgaca cgtttaccta gcaagttttg
    24301 acggaaacga ccttgtttcc ctttcaacat atgagaaaga gatttcaatg ggcggttacc
    24361 tggtccagta actggacgtc cgcgacgacc gttatcgatc aatgcatcta ctgcttcttg
    24421 cagcatacgt ttttcatttt gaacgatgat tccaggtgca ttcaagtcta acaaacgttt
    24481 caaacggtta ttacggttga ttacacgacg gtaaagatca ttcaagtcac ttgttgcaaa
    24541 acgtccacct tctaattgaa ccattgggcg taaatctggt ggaataacag ggataacgtc
    24601 cataaccatc cagcttggtt gatttcctga agcgcggaat gcttctaaaa tatccaaacg
    24661 gcggattgca cgtgtacgtt tttgtccttg tgcagatttc aattcttctt tcaattcggc
    24721 tgcttctgca tctagatcaa cattatcaag taattgttta atcgcttctg cacccatagc
    24781 agcttggaat tcttgtccat attgttcacg tttttcgcga tattcgcgtt ctgtcaacaa
    24841 ttgttttttc tctaaattcg tatttcctgg ttcgatgact acatatgaag caaaataaat
    24901 gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga cccatacgtg aaggaatccc
    24961 tttaaagtac cagatatgtg aaacaggagc tgctaattca atatgtccca tgcgttcacg
    25021 gcgaactttc gaacgagtaa cttccactcc gcatcgatca caaacgattc ctttataacg
    25081 gatacgtttg tattttccgc aggcacattc ccagtctttt gtaggaccaa aaatccgctc
    25141 acagaacaac ccttcgcgtt caggttttaa ggtacgatag ttaatcgtct caggtttttt
    25201 tacttcaccg taagaccagc ttctgatttt ttcgggagaa gccaaaccta tttgcatact
    25261 ttcgaattta tttacatcga tcaaaagggg ttccctccat ttcatttaat ggcaaaccgc
    25321 aagacggctg atcttcgacc gccttgcagc tcatagaccg gattagtcta aattatcttc
    25381 tgcggtttca aagttttgga tgacatcgtc tttttcatct tccacttgtt cagcagcttt
    25441 cttttctaat tctttggcag tttgctgttc ggcaaatttt gtcaaagcat caacagtgat
    25501 caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc tctgtttctt cgatatccaa
    25561 gacacgcatg tccagaccta gtgattgcaa ttctttcacc aatacgcgga atgattccgg
    25621 tacacctggt tttggaattg gttcaccctt gacgattgct tcgtatgttt tcacacgtcc
    25681 gactacgtca tctgatttgt atgtcaagat ttcttgtaaa gtataagccg caccgtaagc
    25741 ttccagtgcc catacttcca tttcaccaaa acgttgtcca ccaaattgag ctttacctcc
    25801 caatggttgt tgtgtaacca atgagtaagg tccgattgaa cgtgcatgca atttgtcatc
    25861 gaccatgtga gcaagtttga tcatgtacat cacaccgaca gacacacgtc catcaaatgg
    25921 ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg ctggccatac cggcttcacg
    25981 aactgtttcc catacgtctt catcacttgc accatcaaat actggcgttg ctacgtggat
    26041 acctaactga cgtgcagcca tacccaagtg taattccaat acttgcccga tgttcatacg
    26101 tgaaggcacc cctaaaggat tcagcatgat atcgattggt gttccatcag gtaggaatgg
    26161 catatcttct tccggcataa tacgggatac aaccccttta tttccgtgac gaccggccat
    26221 tttatcccct tcatggattt tacgtttttg aacgatataa acacgaacta acatgtttac
    26281 gcctggtgac aattcatctc cagcttcacg agtaaagatt ttcacatcgt gaacgatacc
    26341 gccgccgcca tgtggtacac gtaatgatgt atcgcggact tcacgagctt tttcgccaaa
    26401 gatcgcatgc aatagacgtt cttctgcaga taattctgtt accccttttg gcgtgacttt
    26461 ccctacaagc aaatcgccat cttggacttc tgcaccaata cggatgatac ccatttcgtc
    26521 taaatctttt aatgcgtctt ccccgacatt agggatttcg cgtgtgattt cttcaggtcc
    26581 taattttgta tcgcgggctt ctgattcata ttcttcaata tggatagaag tgtatacgtc
    26641 atcttttacc aaacgacggc tcatgatgat cgcatcttca tagttgtacc cttcccaagt
    26701 catgaaacca actaaaacgt tttggcctag agccatttcg ccttgttcca tagatggtcc
    26761 gtctgccaga gtatcccctt tttcgacttt ctcacccaaa tgaacgattg gacgttggtt
    26821 gtagcttgtt ccggagtttg aacgacggaa ttttgttaca tcgtatttat ctaatgcacc
    26881 gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat tcaacgacac cgtcatgttt
    26941 acataacaaa gcagctcctg agtcatgcgc tgatttgtat tccataccag taccaaccca
    27001 tggtgcttga ggattgatca acggcactgc ttgacgctgc atgttggcac ccatcaaggc
    27061 acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg caactacttg
    27121 tttaggtgat acgtccatgt agtctacttt atcaatagat acttctaagt tttcactttg
    27181 agcacgagcc ataacaacgt cttgagcaaa tgttccatct tcattcaatg ggctgtttgc
    27241 ttgggctacg atgtaatggt cttcgatatc agctgtcaag tagtcgattt ggtcagtaac
    27301 acgacctgtt tcacggtcta cacgacgata aggtgtttcg ataaatccga atttatttac
    27361 tttcgcataa ctggacaaac tattgatcaa cccgatgttt gggccttcag gagtttcgat
    27421 cggacacata cggccatagt gggagtagtg aacgtcacga acttcataac cggcgcggtc
    27481 acgagtcaat ccgccaggtc ctaaggctga aagacgacgt ttgtgtgtca attcgccaag
    27541 agggtttgtt tgatccatga actgtgacaa ctgagaagaa ccaaagaatt ctttgatact
    27601 tgccacaact ggacggatat tgatcaattg ttgaggtgtc aatgtttcag tatcttggat
    27661 cgacattctt tcacgaacca cacgttccat acgtgctagc ccgatacgga attggttttg
    27721 taaaagttca ccgactgaac ggatacgacg atttcctaag tggtcgatat catcgacatt
    27781 gccgatacct tccatcaagt tcaagaaata gctcattgaa gcaatgatgt cggctggacg
    27841 aaccgttttt acagctgctt ctggatagcc gtttccgatc acgtttactt cacgttcagg
    27901 gtctcttggt gaaaatactt tgatgacttg gacagtcatt ggatctgtga ccacaccgtc
    27961 ttctgatgga tagtaagtca ctgaatttag gccattatca atgaaaggag ctagtgtttc
    28021 catgacttgg tgagtcagaa ctgttccttt ttcaacgatg atctcgcctg tttctggatc
    28081 aactaatgtt tcagctaatg tcagattcaa tagacgtgtt ttcaaatcta attttttgtt
    28141 tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt ggatcgaaga aacgagcatt
    28201 cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct ggacgcaaac gttcgtaaac
    28261 gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt ttatgcaagt ctttttcgac
    28321 tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag atcgtatcat cggaaccaaa
    28381 tcctaacgca cgaactaata cggttaaagg aatcttacgt gtacggtcga tacgtacata
    28441 agagatgtct tttgcatcag tttccatttc tagccaagct ccacggttag ggataacagt
    28501 agaaccgaat ccttcttttc cgtttttgtc gacttttcca tggaaataga cacctggtga
    28561 acggactaac tgagaaacga ttactcgctc tgccccgttg atgatgaatg ttccttgttc
    28621 tgtcattaat gggaaatcac cgaagaatac ttcttgtgct ttgatttcgc cagtctcgcg
    28681 gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag tttgcatcat gcgcacgagc
    28741 ttctgctact gtatactttg gttctttcaa ttcataatct acaaattcca aagatagatt
    28801 gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt tctctaagtc cctcatctaa
    28861 gaaccattgg taagagtctg tttgaatttc gatcaaattt ggtaattcca acacttcact
    28921 gattcttgcg aaacttctac gttcgcgatg ttttccgtat tttactacgt gtccagccaa
    28981 gctcttcacc cctctaaaat gtcattcaaa aagactaccc gatcaattgt tacaataata
    29041 tttcaaatat tatttttagg taacaacaga cattttttgc ggcttttagg caaaaaaaaa
    29101 ccaaaaatag aacattctct tgaaacctta cttcgtgagc ttctactttt gtttccttat
    29161 attaaagccg aaacggacaa tatttcgttt ctgccttttc ttcatcagat agtttttgca
    29221 acttcatata ctacacttat tttctataaa agtcaacact tcctggcgtt tcttctgctt
    29281 tttcgcaaca ttttcttaat gttttcaatt ttatgttttc aattatctga caattcttaa
    29341 ttgacagacc tttttatctc ggttatactt tagaaaattc attttgtgga ggaacttcta
    29401 tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa taacttttac tttagctact
    29461 ttagataggt ttgtattcat catgatggat acaaacgtta aacgacagtt tgtatctatg
    29521 atggctaaag aactttgtat tgcagcaaaa agccacgtag acaaaatgct aagtggctga
    29581 gcagtgaaaa tacaaagtaa aagtatcaag cattctactt tttcaattta ttttccgact
    29641 tttcaatcca tttggacatt ttgtctgaat ggattttttg tttcccaaaa ttaaggagga
    29701 aaaagaaatg aaaaaaaata taatcatcgg attaggcgct gccctgctac tagctttagg
    29761 aggttgcgca caaaaagaca attccgcaga ggcatcagat ggacaaaaaa caattggcgt
    29821 attgcaactt gtacaacata actcgttaga tgctgcctat aaaggattca aagaaggatt
    29881 agcagaagaa gggtataaag aaggcgataa tctaacaatc gattatcaaa atgcccaaaa
    29941 caatcaagac aacctgaaaa gtatgagtga gaaactcgtc aaagaagatc ctgatttgct
    30001 acttggaatc gccactccag cagcacaatc tttattaaat gaaacaacca ctatcccgat
    30061 gactgtcaca gcggtcacag acttggaaca agcccattta gtcacatcca atgaaaaacc
    30121 tggcggcaat gtgactggca cgacagatat ggtgccaatc gaaaaacaaa tcggcttact
    30181 gttaaatatc gtgccagacg ccaaaacaat cggcatcatg tataacaacg gtgaagcaaa
    30241 ctctaagatc caagctgatt tggcagaaaa agaattgaaa aaagcgggcg tcaaagtcaa
    30301 agtactgaca gcaaattcca caaatgatgt ccaacaagtg acgaaaagtc tagctaaaga
    30361 tgtagatgga atctatattc ctactgataa cacgttcgca agtgcggcaa gtgttgtcgg
    30421 tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc gcagttgatc aagtcaaaga
    30481 cggcggtcta gcaacagtag gaatcgacta cgaaagcttg ggcaaacaaa cagggatcat
    30541 ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt cctgtcgaaa cagcgaatga
    30601 tttggaactg tatgtcaata aagacatggc caaagcatta ggcatcaatc cagacagcat
    30661 caaagaagct gaataaaaca caggaggatt ctcatgacaa atttgctctc tcttttctta
    30721 tcatctgcat cgcaaggggt cttatgggcc ctacttgcga ttggtgtata cgtcactttc
    30781 cgtatcttgg acattgccga cttgactgct gaaggaagct ttcctttagg tgcagggatc
    30841 gcggcagtaa gtattacaaa tggctatcat ccattgacag cttgtcttct aggcttttta
    30901 gggggtgcgg cagcagggct tgtttccgga ctgcttcaca caaaattgaa aattcccgcc
    30961 cttcttgcag ggatcatcac catgactggt ttatattctg tcacatcccg tgtgatgggt
    31021 gcgccgaaca tctctttatt gggtcagcca acgatctttc attgggtcga gtcattcggc
    31081 ataacaaaag acaacgctgt actgatcgtc ggtctgcttt ttgctttgat cgttgtatgt
    31141 ttacttgttt tgttcttacg tacagaaaca ggacttgcta ttcgtgcaac tggcgataat
    31201 ctggcaatga gcgaagcaaa cgggatcaac acagataata tgaagatcat cggttatatg
    31261 atttctaatg gatgcattgc tctttctggc tccttacttg cgcaaaacaa cggctttgct
    31321 gatttaaatt ctggtattgg aacgatcgta attggacttg cttctattat catcgcagaa
    31381 gttttgttac gtaaccagcc actatttctc cgtctcttga ctgtcgtttt aggtgcggtc
    31441 atttatcgtt ttattttagc gttagtcttc gaactgaatg ttgaaccaag tgattcgaaa
    31501 cttgcttctg ctttcgtgct agtgatctgt ctttctttcc cgcagatcca gcaaaaattc
    31561 catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa tgacgtctta acattggaaa
    31621 atctccatca tacctttgaa aaaggaacga tcaacgaaaa tcatgtcctg aaaggcatta
    31681 atctttcctt agatcccggc gacttcgtga cgatcatcgg tggaaatggg gctggtaaat
    31741 ctactttgct gaacagcatc gccggtacat tttctgtcga tcagggtcaa attttattga
    31801 atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc gaaatccatc agtcgcgtat
    31861 tccaagatcc taaactaggg acagccgttc gtttaacggt agaagaaaat cttgctcttg
    31921 ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt caaaccacaa gaccgaacat
    31981 ttttcaaaga ccagctggtt cggctaaatt tggggttgga aaatcgttta tcctcagaaa
    32041 tcggtttgct gtctggagga caacgtcaag ctattacgtt attgatggcc acattacagc
    32101 gtccagaact gatcttatta gatgaacaca ctgcagcgct tgaccctgct acttccaaaa
    32161 cggtgatgga attgacagaa aagctgatca ctgagcagaa tctcactgct tttatggtca
    32221 ctcatgacat ggaagacgcg atccgctatg ggagtcgact gatcatgctg catcaaggaa
    32281 ggatcgtcgt agatatccag caagaggaaa aacagcagct cacagtgccc caattattag
    32341 cgttgttcaa acaaaacagc ggcacggcat taaaagacga tcaagtactt ttatcttcat
    32401 aatcagaaag aggatgggac aaaaaatgaa cgcccaccct cttctttttt ctctttcctt
    32461 ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga aaactatttt gttctctcct
    32521 tcttcctgat agaatggatg ggaaaggagc ttgatgccat gacaacgaaa gacaaggtac
    32581 ttcaattatt gaaaaagaca ccagattttc tttccggaga aaagttggca cagcaactgg
    32641 aagtttcccg gacaagtatt tggaaagcca tcaaagaatt ggaaaaggca ggctatcgtt
    32701 ttgagcacgg gcctacaggg tatcgttacc tgccctctga cgtactagat gcaaaagaaa
    32761 tccagcaaga gctacggtcg tttattcctg atttgaaagt acaaacgatg ttgacttctg
    32821 aatctacgat gaaagatgcc aaactggcag cagctcaagg agattctgtt tcgaagttat
    32881 ttgttgctga tacacaagaa caagctcgtg gacgttttgg acggcctttt ttcgctgaac
    32941 ctggacgagg aatctacatg agtctcttgc tccatccaga caaacggttt gatgaattgc
    33001 ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc cattgaatct gtaaccggtc
    33061 gttctgcttc gatcaaatgg gtcaatgata tctacatgga tggaaaaaaa gtctgtggga
    33121 ttttatctga agcagtcagt gatatggaaa gcggcaggat cagtcatatc atcattggga
    33181 tcgggcttaa tttttctgtt cctcaaaatc attttccagc tgatctccaa gaaaaagcca
    33241 tctctgtctt tcccgacgga caagctagtg tcacaaggaa tcagctaatc agcaaaatct
    33301 ggcaagaatt gttcacttat ctttctcacc cagaaaaagc gttggacttc tataaagaaa
    33361 aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa aggaacgact tatgtcggtc
    33421 ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca aacaaatgaa cagaagatga
    33481 gtttgtcttc tggcgaaatc agtctcacat ctatccgtac gcaataatta tcagatttca
    33541 caaaaggaca cctgatctca tacagtgtcc ttttttctga attctcttca aaagactctc
    33601 cttattctat cagctgacag tttctctatc ctctagaaaa aggtattcta aaaatatcta
    33661 taaagcatgg tacactttct ttaaatgaat caatgcaaaa aacaagagag tcatcagttt
    33721 acacgatcaa aagagatagc aggccgcttc ctttttcaat cttatagata gaccatgggt
    33781 aacgataaaa acaaaaaaga acttgcgact tattttgccg taagttcttt tttagctagt
    33841 gccttaatct cttaatccca acaaacgtct cgcatagatc acctgaccag agtgcatagc
    33901 agcatcatca ataatagaaa cgagacgcat tcctcgtgtg actggtggtg tccagttctc
    33961 gtcaattact tcatctagct cggaaggttc cagccttctt aagtaagaaa tagcaaaatc
    34021 agcagctcct cgcaagtatc ctagcagatc ttctatttga ttagcttgga tctgctttgc
    34081 ttgttccaga ctatgcttcc aatcttgttc gttatctgct atcgtcatcg gaaaccggct
    34141 ttcccagtct tgactatgcc aaattggaga agttcctgct aaatcagcaa tctggaaatc
    34201 taattctcga gcggtatgcc aagccagcca agtcattgat ttgatctgcg gggctctatc
    34261 ttccactgga aaacgattgg cctcctcaat agagacgcct tcaaacaaac gttcaaaccg
    34321 atcgtatgcc cgatccacac tctcgcatag catatctaaa taatccattt attttcctcc
    34381 tttttattta tcctacttac tttttcctaa ttctaggata cctacttata tgttactaca
    34441 cacccttatt ttttacactt taacagtcac catcatcaat agtttggaga ttgaaagaaa
    34501 aagatagtgt cgaactatca attgaacaag aagcaacaat atgaacgttt cattaatatt
    34561 ctttaaataa acaatgattt ttcaaacgaa cagtttaaga ctaggagaaa aagagtataa
    34621 taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa aaaagggcaa gtttactagt
    34681 cctagttgct ttgttgttca atatcttttc gtatggtgtg gccgtttcag cggaaacata
    34741 cattcctaaa gaccctggga atatttataa tgatctaact ggtaactatg gcttgttagg
    34801 aattgctagt caattccacg tatttgctaa aaataagaca actgtgaatg cacatacaga
    34861 cggaaatata gcaacacatg aacttgatgc aaaaaataat tttggtacag agcttcatga
    34921 aggtttattg aaccaagaaa taaattatat acaaaaaact gattctttcg ctaattcttc
    34981 aggcatacct acaggtagca caagaatgaa taaatttgtc gttggcagta acgtggatgt
    35041 agcacttcaa gatggtcatc ctacagtcaa tggatccagg cttgatcact taactccaga
    35101 tgatttttat aaagatcgtg ctgggcatga atatattgat ttcgagcagg aatttgctaa
    35161 attgaatgta gcagcaaatg atcttgcaac gatcactcca gctaaaacat atactgctgc
    35221 agattttcca gacatgaaca atcggacaat cgatttaact gatttatcag ataccgggtt
    35281 tttattggta aatatcgatg cagaagtgtt aacgatgaat acgccacttc aaatcattaa
    35341 tccaaatgat caagtagttg tatttaatgt catcaacagt tcttctgcat tgaacgtaca
    35401 gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca gaagattttt cggatgcgaa
    35461 tatctcttgg aattttggaa atgagatgac tgatttgaca atcagtgctc cttttcaagg
    35521 aacaatcctt gcgcctaatg ctactatccg cattactcaa aaccaagacg gaacgattat
    35581 aggaacaaat gtgattttag atgcagctac caatcgttgg gatcctaacg aaatatttat
    35641 cagcgacaat ggtacagata cgacagacac aagcgacagt acagatacat ctaccacaag
    35701 tgatagctca gattcatcaa cttcaagcga cagtacagat actacctcta ccacaagtga
    35761 tagcacggat acatcagctt caagcgacag tacagatact acctctacca caagtgatag
    35821 cacggacaca tcagcttcaa gtgacagtac agatactacc tctaccacaa gtgaca
//
LOCUS       DARPZF010000023        35021 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.024, whole genome shotgun sequence.
ACCESSION   DARPZF010000023 DARPZF010000000
VERSION     DARPZF010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.024"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(56..2653)
                     /gene="adhE"
                     /locus_tag="SLE65_001481"
                     /gene_synonym="adhC"
     CDS             complement(56..2653)
                     /gene="adhE"
                     /locus_tag="SLE65_001481"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEI8448781.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(2958..3338)
                     /gene="yajC"
                     /locus_tag="SLE65_001482"
     CDS             complement(2958..3338)
                     /gene="yajC"
                     /locus_tag="SLE65_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEI8448782.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(3435..4580)
                     /gene="tgt"
                     /locus_tag="SLE65_001483"
     CDS             complement(3435..4580)
                     /gene="tgt"
                     /locus_tag="SLE65_001483"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEI8448783.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            4798..5496
                     /locus_tag="SLE65_001484"
     CDS             4798..5496
                     /locus_tag="SLE65_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEI8448784.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(5664..8303)
                     /locus_tag="SLE65_001485"
     CDS             complement(5664..8303)
                     /locus_tag="SLE65_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEI8448785.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(8922..9953)
                     /gene="queA"
                     /locus_tag="SLE65_001486"
     CDS             complement(8922..9953)
                     /gene="queA"
                     /locus_tag="SLE65_001486"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEI8448786.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            10146..11321
                     /locus_tag="SLE65_001487"
     CDS             10146..11321
                     /locus_tag="SLE65_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HEI8448787.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            11325..11966
                     /locus_tag="SLE65_001488"
     CDS             11325..11966
                     /locus_tag="SLE65_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8448788.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            11963..12880
                     /locus_tag="SLE65_001489"
     CDS             11963..12880
                     /locus_tag="SLE65_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HEI8448789.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            12877..13548
                     /locus_tag="SLE65_001490"
     CDS             12877..13548
                     /locus_tag="SLE65_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8448790.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(14089..14577)
                     /locus_tag="SLE65_001491"
     CDS             complement(14089..14577)
                     /locus_tag="SLE65_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HEI8448791.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(14778..15044)
                     /locus_tag="SLE65_001492"
     CDS             complement(14778..15044)
                     /locus_tag="SLE65_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEI8448792.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(15044..15307)
                     /locus_tag="SLE65_001493"
     CDS             complement(15044..15307)
                     /locus_tag="SLE65_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEI8448793.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            15783..15968
                     /locus_tag="SLE65_001494"
     CDS             15783..15968
                     /locus_tag="SLE65_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEI8448794.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(16110..17933)
                     /locus_tag="SLE65_001495"
     CDS             complement(16110..17933)
                     /locus_tag="SLE65_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HEI8448795.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(18531..21236)
                     /locus_tag="SLE65_001496"
     CDS             complement(18531..21236)
                     /locus_tag="SLE65_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEI8448796.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(21542..22489)
                     /locus_tag="SLE65_001497"
     CDS             complement(21542..22489)
                     /locus_tag="SLE65_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HEI8448797.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            22679..22948
                     /gene="rpsN"
                     /locus_tag="SLE65_001498"
     CDS             22679..22948
                     /gene="rpsN"
                     /locus_tag="SLE65_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEI8448798.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(23124..23486)
                     /locus_tag="SLE65_001499"
     CDS             complement(23124..23486)
                     /locus_tag="SLE65_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HEI8448799.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(23497..24618)
                     /locus_tag="SLE65_001500"
     CDS             complement(23497..24618)
                     /locus_tag="SLE65_001500"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEI8448800.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(24634..24984)
                     /locus_tag="SLE65_001501"
     CDS             complement(24634..24984)
                     /locus_tag="SLE65_001501"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEI8448801.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(25114..26625)
                     /locus_tag="SLE65_001502"
     CDS             complement(25114..26625)
                     /locus_tag="SLE65_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEI8448802.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(26947..28299)
                     /locus_tag="SLE65_001503"
     CDS             complement(26947..28299)
                     /locus_tag="SLE65_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEI8448803.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(28452..29528)
                     /locus_tag="SLE65_001504"
     CDS             complement(28452..29528)
                     /locus_tag="SLE65_001504"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEI8448804.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            29724..31469
                     /locus_tag="SLE65_001505"
     CDS             29724..31469
                     /locus_tag="SLE65_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HEI8448805.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(31749..32186)
                     /locus_tag="SLE65_001506"
     CDS             complement(31749..32186)
                     /locus_tag="SLE65_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HEI8448806.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(32170..33543)
                     /locus_tag="SLE65_001507"
     CDS             complement(32170..33543)
                     /locus_tag="SLE65_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448807.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(33865..34353)
                     /locus_tag="SLE65_001508"
     CDS             complement(33865..34353)
                     /locus_tag="SLE65_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8448808.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(34375..34977)
                     /locus_tag="SLE65_001509"
     CDS             complement(34375..34977)
                     /locus_tag="SLE65_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEI8448809.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         9919 a         7476 c         6466 g        11160 t
ORIGIN      
        1 ttttccaagt tctttttcat ctattttctt atcttttttc tacgctttct tttgcttatc
       61 cgttgtaagc atcaatgatg atctgtttca attcagagat caatggttct ttcggattag
      121 ctgtcgtaca ttggtcttcg taagctaatt cagccatacg gtctacggtt gtatctagtg
      181 tttcttgtgt gactccttga gcttttagac tcatgttgat gccgacagat tttcctaatt
      241 cataaacagc cgttgctaaa gcttcgacta attcctctgt tgtttcgcct ttcagaccta
      301 agaattttgc gatatctgcg taatctgtat ctgcacggaa atagtcatat ttagggaaca
      361 tcgcatgttt ttgtggatct tttgcattat agcggataat atgcggtaaa agaatcgcat
      421 ttgtccgtcc atgagggatc ccgtattccc cgccgatttt atgtgcgact gagtgacaaa
      481 tacctaggaa tgcgttagca aacgccatac cagccattgt agaagcgttg tgcatttttt
      541 cacgtgattc catatcaggt gtttttactg atttttctaa atagtcaaag actaacttga
      601 ttgcttgtag gctcaatcca cgtgtataat ctgaagccat gactgaaaca taggattcga
      661 ttgcatgtgt taacacatcc atcccggtat ctgctgtgac agatgctgga actgacatga
      721 cgaattgagg atcgacgatt gcgacatctg gcgtcaatgc ataatctgct aacggatatt
      781 tcacatgtgt ttcactgtca gtgatgaccg caaatggcgt tacttcagaa ccagtccctg
      841 atgttgtcgg gatacatacg aattgtgttt tttctggttt gtcgatctta tatgtccgtt
      901 tacggatatc caagaatttt tgttttgcac caaagaaaga tgtgtctggg tgttcataga
      961 acatccacat tcccttagct gcgtccattg cagaaccgcc tccaagagcg attactgtat
     1021 ctggcttgaa gtctgccatc agtttcgttc ctgcgtatac ggtatttgtc gatgggttcg
     1081 gttcaacatc tgagaagact tcgatcttca catcattttt acgtcgtgcc aatacttcac
     1141 gaactgtatc gcagtaaccg aattggacca taccagggtc acaaacgatc atgacacgtt
     1201 caacgttttc cattttctct aagtacaata gagagttctt ttcaaagaag atttttggcg
     1261 gtaatttgaa ccattgcatg ttatttctcc gtttcgctac agttttgaca ttgattaagt
     1321 ttacagcaga gacgttacga gaaacagagt tcttaccata agaaccgcat cccaaagtca
     1381 atgacggaat catttcgtta tagatatcac cgatgccgcc ttctgcagat ggtgtattca
     1441 ctaaaatacg acaagctttc attcgaagac cgaatttgac atgcaactct tcgttttctg
     1501 aatggataac tgctgtatgt cctaatcctc caagattcaa cataccttca cacaaatcaa
     1561 acgcatggtc cgtgttgtta gctttgatca tggcaagaac tggagaaagt ttttctcttg
     1621 atagcggata atctgggcct acgccttcca attcagcaat cagcattttc gttccttttg
     1681 gtacactgat tcctgccaat tttgcgattt ccatcgcaga atgtccaacg attgatggat
     1741 tgaccgcata ttttccttcg ttcatcactg catcttctaa tttttgcaat tcatctggtt
     1801 ttacgatata aacttggtgt gcttggaatt ctgcttttac tgctgcatag atttctttat
     1861 ccacgatcac agcttgttca gaagcacaaa tcattccatt atcaaatgtt ttcgaaacga
     1921 tcaaatcgtt cactgcacgt ttaatttttg ctgttttttc aatataagct ggtacgttac
     1981 ctggacctac acctaaagct ggttttcctg tagagtaagc agacttgacc attccagctc
     2041 cacctgtcgc taagacgatc gcgatacctg gatggttcat tagcatagaa gtcgcttcga
     2101 tcgaaggatg ttcgatccat tggatacaat tttcaggagc tccggcagcg atagcagcat
     2161 cacgtaccac tcgtgctgct tctgcagaag atttttgggc acttggatgg aaagcaaaaa
     2221 cgattggatt tcttgttttc aacgcgatca ttgatttgaa aatcgttgtg gaagtcggat
     2281 tcgttgttgg agttactccg caaaccacac cgactggttc agcaatttca atcaaccctt
     2341 tttggacatc ttcattgatc acaccaactg ttttatcatg tttgatatta tgccaaatat
     2401 attcggacgc atacatattt ttgattgctt tatcttcgta aacaccgcgg cctgtttcct
     2461 ctacagccat cttcgctaat ggcatatgtt gatccaaagc tgccattgcc atttcatgca
     2521 cgatatggtc tactttttct tgatcaaagc tttccatttc tttcaatgct gcatttgctt
     2581 tttctgccaa atcatcaatc attgcttgta cgtcaattgt cttcgttttt tctttttcta
     2641 ttactttagc catcattatc ctcctaatgg gtcatggtta tttgttaaat aattcacatg
     2701 tatatcatac aatatttatt tttctatgta aacacttttt tgtgattttt ttcacagtta
     2761 tttttaaata taaaattgct ttatttacag gtgtttgtat agaaaaatat ataaagttat
     2821 ttattattat ttatatgaca cacccgatta ttcaatattg agcaatatat cccatgctct
     2881 tatctctttc ttttttgaat aaaaaatgag gtaggacatc tttctgccct acctcgtctt
     2941 taaataagct ttgatactta tttttcttcc ttctcttctg tctcttccag cgtttctgtt
     3001 gtttcagttt ttacttcaac tgtctcagct ggttcttctg ttgtttcaac agtagtcgtt
     3061 gcatcatttg ttacgacagt ccctggtttg accgttttga ttgctgcacg atcgtactca
     3121 aggaagatcc cttcgcagtc taaaacaact gtccgtttgt cattgtcgat ttctgaaaca
     3181 actccatgta atccgccgat cgttacgact gaatcacctg gtttcatgct atctaacaag
     3241 ttttgacgtt cttgctgttg tttcttttgc gaacgtgaca taaaaaacca cattgctaat
     3301 agcgcgataa acatcacaag cattggtaat gttcccattt ttttcacctc actaattctg
     3361 tatctacaaa aaacacttta gcagaaaaat gctgataaca ctagtttttt acttaatttt
     3421 taaaagattt tcctttagaa gctttttgcg ttttctttat tgaacccgta ttcttcaaaa
     3481 aaggcttctc taaattcaag caaattatca tccatgattg cttgacgtac ttgtttcatt
     3541 agattcaaca agaagtataa attgtggtaa gaagtcaaac gaatcccaaa tgtttcatca
     3601 catttgatca aatggcggat ataggcacgt gtatagtttt tacatgtata acaatcacat
     3661 ttctcatcaa ttggacggaa atcatgggca tatttcgcat ttttcactac tagacggcct
     3721 tgagaagtca tacatgtgcc atttcgagcg attcgagtag gcaagacaca gtcaaacatg
     3781 tctactccac ggataacacc atcgatcaat gaatcagcag caccgacacc catcaagtaa
     3841 cgtggtttgt tttcggggat caacggtgta gtgaattcta atacacgatt catttctgat
     3901 ttaggttccc cgacagataa cccgccgatt gagtaaccag ggaaatccat cccgactaga
     3961 tctttcgcgc tttgacgacg aagatcttca aaccctgctc cttggatgat tccaaataat
     4021 ccttgacggt ctggattagc atgagctttc aatcctcgtt ctgcccatcg agacgtacgt
     4081 tctactgatt ttttcacgta gtcgtaactt tcatcgaatg gtggacattc gtcaaaactc
     4141 atcatgatat cagagcccaa tttattttgg atgttgattg ctttttctgg tgataaaaac
     4201 atacgcgaac cgttcaagtg atttttgaaa tgcacgcctt cttcttcgat attccgcata
     4261 tcacttaatg aaaaaacttg aaagccgcct gaatctgtta aaatcggttg atcccagttc
     4321 ataaatttat gcagtccgcc agcttcttct actaagtctt caccagggcg tagccataaa
     4381 tgatatgtat tacttaaaat aacgccagca cccatttctt tcaactcttc tggggacatt
     4441 gtttttactg tagctaatgt tcctactggc atgaacattg gtgtggggaa agttccgtgt
     4501 ggcgtgatca attcccctaa acgcgcgcca gtatgttttt ctttcttgat taaacgatag
     4561 cgaatggcag gttgcgtcat tcatttccct actttctata taaaatatct tgacaactcc
     4621 caccatcata atcgtttcaa gtgctttttg caagttccct cggcttcctt ctactttatt
     4681 taatattctt ttttttatcc tttttttatg aataacaaaa aaaagaaaaa cattatgaca
     4741 gaaatatttt ttgatacatg gtatattggt gttattaaag aaaaggaggg aaaaatcatg
     4801 caatcttctg cagaattaaa acgccaagca aaagagagtc taaaaggacg ttggggacaa
     4861 gctgttttac taaatctaat ccctacattg attggtattg ctactattct tcttattatg
     4921 attcctatta tcttgtttgc caccaccata tatgatggat cagcgagcgt ctcagaagcg
     4981 acaacttcag gaggcggtag ttcaggaggc ggtggcggaa ttatttccag catcattagc
     5041 gctttgttca tgagcggtat ttcttggact tatcttgata ttttacgtgg acaaaaagat
     5101 cagatcgaac cattcaaaga tgcatttcgt ggattcaaag gtttgtttat cggcggagtg
     5161 atcagcttag ctgtgctgat ctcgatcttt acaacattat ggggtttgct attagttatt
     5221 cctggaatca ttaaaagcta ttcttattct caaagctatt ttatttacta cgatatcgtc
     5281 caagaaacag gacaaacacc taaagtactg gatacgatca ctgcaagtcg aaaattgatg
     5341 gatggttata aaggacaact tttctggtta gatctttcat ttatcggctg gcatatctta
     5401 gcattagcaa ctgctggtat tggttatcta tggctcagcc catacatttc tgcaacaaaa
     5461 gcagcatttt atgaacaatt gccaaaagat atttaaaaga gagtgtgact tgtgaccgag
     5521 ggggtggcag gagaacaccg tttatcgaga ggcagtaaaa gaaacattca gcccattagc
     5581 aaaaaggagg tgtgacaaca ttcatgtcac acctcctttt tgtatagttc cagtaaaaag
     5641 aaaatcaact tagaaacagt taatcattcc tcttcttctg cttccggtaa tcgatggaac
     5701 ttgatcagtt cattcaccgc gattggtacg atagataaaa tccctaccaa gaaccagtga
     5761 ttcaaactga tgtgtactag gccgaatagt tcttgcgtaa atggcagcaa agcaacagcc
     5821 gttgtaatag ctaatgccag taacgccatt tctaccaaag ctttattggt cgctaaattg
     5881 actttgaaga tcgattggct gctgcgtaca ttgaacacat gcagaatcga tgaataagct
     5941 aagatcaaga atgcaacagt ttgaccgaca tgctgacttg cgtctaccca tgggctgata
     6001 gtatcgacat aactacctaa ataataacca aacaaggtta cgatggtgaa gacccctgca
     6061 tttatggcaa ttttttgcaa taaacctcga gcaaagatcc cttcattttt cggaatgggt
     6121 ggctgatcca tgatgccgtg ttccgctggc tctcttccta aagcaaatcc tggaagtcca
     6181 tcagcaacta cattgacaaa cagtagttgc acagctgtaa atggtgctcc ccatcctaac
     6241 agcatcgcaa tcaaaacaat aaagatctcc gaaatattac agcttagcaa aaagttgata
     6301 gctttacgaa tattctgata aaccgaacgt ccttgactga cagcgtctac gatcgtcgca
     6361 aagttgtcat ccgtcaaaat catatctgcg gcactttgcg ccacatctgt tcctgtgatc
     6421 cccatggcac acccaacgtt acttgctttc aacgctggtg catcattcac accatcccca
     6481 gtcatcgcta cgactgcacc cgtacgttgc caagatttga cgatccggat cttgtcttct
     6541 ggcgttaccc gagcatagac agagagagct ttgacacgcg catctaattc ttcgtctgat
     6601 aattgatgca gttctgatcc tgaaagtgct tctgacggat cattcaagat acctaattct
     6661 ttcgctatgg cactggcagt caccacatga tctccagtga tcatgactgt tttgatgcca
     6721 gcctttttcg ctcgcttgat tgctccttta ctttctggac gtggtggatc gatcattccg
     6781 atcagaccaa tcaaacgtaa gtctttttcc agtgcttcag aagaaatatc ttgcggttct
     6841 tcgtcataag tagcataacc aacagcaatc actctcagtg cccgtttacc aaagcgatca
     6901 ttaacgatcg ccgcttgttc tacatcgcct gaactaaagc gcggagcaag aacatcgaat
     6961 gctcctttgg tgattgagat gtatttttcg cccatttggt gaactgttgt catcattttt
     7021 cgttcagaat caaaaggaag ctcgtttact cgtggatatt tttcttctaa ttctgccttt
     7081 gtatgataat tctcttcaac agcccttacg atggctactt ctgttggatt acctttgata
     7141 acaaggtcgt catcttcttg ctcgaccgtc acatctgtac atagtgcagc cattttcaat
     7201 atttccatcg cgctgttcgt cattgaatct tcgatattcg ttacttcatc ttctttgctc
     7261 catacccggc ggacgcgcat ttcattttgt gtcagcgttc ctgttttgtc tgagcagata
     7321 acattagcgg ttcctagcgt ttcaactgct ggcaactgtc ggatgatcgc atgtttcctc
     7381 gccatcttct gcacaccgta tgcaagtgtc aacgtaacaa taacagtcaa ggtttccggt
     7441 acagctgcaa cagccaagga aatcgaagtc atgaacatct caaggagtgg ttctccttgc
     7501 agttcaccaa tcacaaatac taaagccgca gccgctaaag cgatcatact gattcgtttg
     7561 cctagctgat tcaatcggac ctgtaaaggt gttttttgca tagtattttc gttcaaaaga
     7621 tccgcgatct tacccatttc tgtagccatg ccaatggcag tgacgatcgc tttcccacga
     7681 cctgcagcaa ccgtacatcc tttaaatacc atattaagtt ggtcacctaa tgactcatct
     7741 tcttcagcaa taaatgctgc atctttttca actgcttcac tttctccagt caacgccgat
     7801 tcttctacac gtaattgtga tgcttcgatc aaacgggcat cggcagaaat agcatcaccg
     7861 gactctaaaa caagaatatc acccactacc agttgctctg actcaacagt ggtcactttg
     7921 ccgtctcgta tgacagttgc cgtttgttta ttcatatctt gcaaggattc cagtgctttt
     7981 tctgcgtttc cttcttggac aatcgccaat accgagttga tcacaacgat agcgatgatc
     8041 agcagtcctt caaataaatc cccatgttct gtagcaaatg cggtataaaa ggaaatcacc
     8101 gctgctacaa gaaggatgat cgttgtaaaa tcggacaagc ttcgaaagaa ttttttgatc
     8161 atcgattctt tcggcgcctc atcgaattta ttcaatccct gcttttttcg ccgttcatcc
     8221 acttcttgtg aagacaaccc agtatctgga tctgcttctg ttaccttctt tacttcttct
     8281 attgtctgct tgtattcttc catcctattc ctcctttaaa atcttcgtac aaaaaaaggt
     8341 acttatttta ctataacatc ctttttttat ttacttcaaa taaagggctt atcgattatt
     8401 tgttaagaaa gcgtaaaatt taaagtgctt atatttgcaa acgctaccaa aggatgctat
     8461 tatatagatg taaggaagga ggataccatc aaatagacag aagaatttct cgatagaaca
     8521 gtgtaagcaa acaaagttgt tagaagtaca ggtttcaccc agacatgcgt gtagagtaca
     8581 aacctataaa tagtgaatgc gtatggatgt ttggatcacg aagtatccga aacaagaagt
     8641 aatgcgatac gtaacaattg aataacgtaa acgtctgaaa attgaatagg aacaagagat
     8701 gtttcaaatg ttgaagatgt aacgaaaaca aaatttttgt ttaacatgaa gaaattcaac
     8761 accgtgcttt gcatgtatga tggaaagtta caatcatttc tgtttatttg aatccttccg
     8821 aggtacaaga aagccgagct tatcgagagc tcggcttttt ctttgtcata aaatctttgt
     8881 aaagcttttt tgttattcaa aactagcggc ttttcataac cttatttcac gaacatcgca
     8941 tctccaaaac taaagaaacg atagcgctct tcaatcgcat gctggtaagc agataaagtc
     9001 aattctcttc ctgcaaaggc actaactaac atgactaaag tcgattttgg caaatggaaa
     9061 ttagttgaga aagcttctac cactttgaat tcatagccag gcgtaatgaa aatatcagtc
     9121 catccgctgt ctgctttgat ttctccatta aatttcgttc caatcgtttc taatgttcga
     9181 attgaagttg ttccgacagc cacgattttc ccgccatttt tacgtacttg gttcaatcgc
     9241 tcagccgctt cttccgtcaa acggtagaat tcactatgca tatggtgttc ttcaatttta
     9301 tctacgctga caggtcggaa tgtacctaac cctacatgta gtgtcagata gactaattca
     9361 acaccctttg cttcgatctc atcaagtaat tctttcgtaa aatgcaatcc agctgttggc
     9421 gctgcagcag aaccattttc tttcgcatag acagtttgat agcgatctgg gtcttccaga
     9481 cgttctttga tatatggagg caatggcatt tctcccaatg attcaagaat ctctagaaaa
     9541 attccttcat actcaaagtc aatgatccgt ccgccgtgtt ccaattcttc tttcactact
     9601 gcttgcaatc tgccatcacc aaaagagatt cttgtcccaa ctttggcacg tttcgcaggt
     9661 ttgatcaatg tctcccacgt atctccttgt gtattcgtta gaagaaggac ttctaaatgc
     9721 gcaccagtat ctggtttttc tccatataaa cgagcaggca gaactcgtgt attattcata
     9781 actagcgcat caccaggctg taactcttca atgatttcat ggaaatgttt atcttccatc
     9841 tctccagttt tccgatccaa aacaagtaaa cgagaatgat cgcggtcttt taatggtgtt
     9901 tgtgcgatta attcttccgg caagtcaaaa tcaaaatctt ctgttgttaa catatcgtca
     9961 ctcactttct atcatgtgct tcatcattct atcatgtttt tcgttctgtt ggcaaaatca
    10021 gcactttttc acttctattt tttgttttcc taaataaaaa aactacccta tttgtatttt
    10081 ttcattgttt taggcatact agtaatagat agttcttcat tgaaaataga aaaagaggtg
    10141 gcaccatgat tgaatttcaa aatgtgtcaa aaatttataa aggtggaaaa gtcgctgtag
    10201 aggacgtcaa tctttcattt gaaaagggtg agttcatttg ttttatcggt acgagcggaa
    10261 gcggaaaaac gacgacgatg cggatgatca accgaatgac tgatccaaca caagggaaaa
    10321 ttttgattga tggaaaatcc atccaagaaa ttgatccagt ggaattgcga cgtcagatcg
    10381 gctatgttat ccaaagtatt ggattgatgc ctcacatgac gatccgtgaa aatatcactc
    10441 ttgtccaaaa attgttgaaa gtcagtcaag aagaacggaa taaaacagct gaaaaaatga
    10501 ttgatcttgt ggaattgccc cgtgagatgt tagatcgcta cccacatgaa ttatctggtg
    10561 gtcagcagca gcgtattgga gtcgttcgtg cccttgcagc gaatcaagat atcatcttga
    10621 tggacgagcc attcggtgcg cttgatccaa tcactcgtga ttccttgcaa gaccttgtca
    10681 aagatttaca agagcgtttg ggaaaaacga tcgtatttgt aacccatgac atggatgaag
    10741 cgattaaact agcaagccgt atcgccatca tgagtgaagg ccgtgtgatc caatttgata
    10801 caccagaaaa tattttacgt catcctgcaa acgatttcgt agaagagttg attggagaag
    10861 atcgcctact acaagccaag ccaaatgcga caagagtcgg cgaagttatg ctaaatacag
    10921 caatcacgat tacaccggaa aaatcattac aagaagcaat caaactgatg agggaaaaac
    10981 gtgtagatac gttgttagtt accgataatt cgaatgtatt aaaaggattt atcgatgtag
    11041 aaacgttgaa taaaaaacga ggaaaagtat ccagtgtcgg cgacattttg aataaacatg
    11101 ttttttacgt aaaagaatcc gcctatcttc gtgatacctt gcaacgcatt ttaaaacgcg
    11161 ggctgaaata cgtgccggtc gttgatgaac agaacaaagt cgtaggtatc ctgactcgtg
    11221 catcattagt ggatatcgtc tacgatgtga tttggggaga agatcccgca actactgatg
    11281 ttgcagagtc agctactcct gaagaatcta aggaggtctg acctatgcag cagttttttc
    11341 atcagcacgg ttcagaaatt ctctcaaaag gttttgaaca tctttatatt tcaggacttg
    11401 ctttgatcat tggtatcatc attgctgtac cgcttggtgt cttactgaca cgttttccaa
    11461 aagctgccac gattgtgatt ggcttaacca gtgccttgca gacaatccct tctcttgctt
    11521 tattggcatt gatgatcccg ctatttggcg taggtaaatt acctgcgatt atcgcactct
    11581 ttatttattc attattgccg attttacgta atacgtacat tgggatgaaa aatgtcgatt
    11641 ggaattatcg ggatgtggca aaaggcatgg ggatgactga gttccaatcc attttttccg
    11701 ttgaattgcc cattgctatg ccaacgatca tggctggtat tcgtttagct gccgtttacg
    11761 tgattgcatg ggctacactt gcctcttata tcggcgctgg tggtttaggc gatttgattt
    11821 ttagtggact gaataattac caaccagatc tcattttggc aggtacgatc cctgtaacaa
    11881 ttttagcact attggctgat tggcttctag gtctcttgga acaccggctg acaccgatcg
    11941 cacttagaga ggagaatgaa gaatgaaacg tatactaaaa atgaccatgg ttcttttctc
    12001 tcttcttata cttgcgagtt gttccttccc tggtcttgcc agcaatacag atgaagacac
    12061 catttcgatc acaggtggaa tcacttcaga agcacagatc ttagcaagtc tagttgccgg
    12121 aatggttgaa cattatacag ataaaaatac cgcaatcatc aacaatctgg ctactacaac
    12181 tatcaaccat caagcgatga tgaacggaga tgcttcaatt tcagcggctc gctacacagg
    12241 aacagattta acgactacat tgaaccttcc tcctgaaaaa gatccgaaaa aagcgtttgc
    12301 taccgtgaaa gatgaatttg agaaaagata cggtcaaacg tggttcccgt cctatggttt
    12361 tgaaaatacg tatgtctttc ttgttcgaaa agacaccgca caaaaatacc atctatctaa
    12421 agtcagcgat ctgaaaaatg tagcggatga attagtagct ggtgtagata cttcttggat
    12481 caatcgtaaa ggagacggtt atgacggctt ccaagaaact tatggcttct ccttcaattc
    12541 gatattacct atgcagattg gacttgttta tgacgcagtc gaagcaggaa aaatggatat
    12601 tgttcttggc tactctacgg atggacggat cgccagttat gatctagtca tgttggaaga
    12661 tgatcgtcaa ttcttcccac catatgatgc tgctccagtt gtagacaaca agatattagc
    12721 tgatacgcct catttaaaag aagccttaaa taagttaggt cataccatca gtacggaaaa
    12781 aatgcaggaa ttgaactacg aagcagataa taatctagtg gaaccatcag tagtagcaca
    12841 acgtttctta caagaaaacc actattttga agggaagtga agcaattgga taaaatgaat
    12901 gtctttcaac aatttttcta ttatttccag gaaaatggct cctatatctt tgcacaattt
    12961 atccgtcact tcctgatttc tatctatggt gtcctctttg cagcagttgt cgggattccg
    13021 gttgggatca tgatttctag gagacgtaaa ttagcaaact gggtgattcg tttggcgaat
    13081 atcatccaga cgatcccttc tctagccatg atctccattt taatcattgg attaggcctg
    13141 ggagtcaatg tcgtgattgt tactgtattt ttgtattccc tcttaccgat catcaagaat
    13201 acgtataccg ggatgatcca agtagacaaa aacatccttg atgtcggcaa aggcatgggg
    13261 atgactgcta gacaacgact attcatggta gagttaccac tctctgtttc tgttatcatg
    13321 gcaggcataa gaaacgcgtt agttgttgcc atcgggataa ccgcgatcgg tgcattcgtc
    13381 ggtgctggtg gtcttggaga tatcattatc cgaggaacca atgcaacaga gggcacatcg
    13441 attattttag caggtgcatt gccaactgca ttaatggcga tcatcacgga ctggctttta
    13501 ggtattttgg aaagacggct agatccagcc agccgtacat cacgctgatg ttattgtaaa
    13561 aaacaaaagc ttctgcgacc atttgttggt cgcaaaggct tttttagttc tgtcattttt
    13621 aaggcaataa tccactctga ttcttccctc cttatgggca aagagttgct tttcttagct
    13681 atttatccat tccgtatact ccaacttcat actgccaacg ggttcatatc tgcatccacc
    13741 gactaagttt ttttcttatc cgctaaggca ttttgccaat ccattttccc atcactcgtc
    13801 atggaattca taccacatga tctctaaata ctcgtctgct tgttctttga attgggcatc
    13861 aattcttaca tcctttggcg tggctttcat ttaagccttt tccatcagtc ctcgattgtt
    13921 cgatgccttc agctgcatca tcaaaactgg tgactgccgt atcggtaact tcgatcatct
    13981 tttatacaat cgggaacttg ccatcctcat ccttggctaa aaacatatct agccattcca
    14041 gcttctcgcc atgggaggtt tgcggttcct aaaaccggta cacgattctt atggactgca
    14101 tccgtcgcaa ctagacttgg cgatacgatg atccttcacc agaagagcac ccccgtaaac
    14161 caattgatcg atatattgcc aataagaaaa gacattggcg taaaagatat cgatccctcg
    14221 tgatgcattg ccgttgatac tgctattcat ggccgaaagc gccacgactt taacttcttc
    14281 cgtttgagtg acattcatgt tcggcaatgt cgctttggat acccgctctg ctaaaggaac
    14341 gacactggta ttgtatttcg tatctgtatc ttttccaaaa gaccatgcca acgaatcctc
    14401 tgggaaccaa taagacgact ccggttgatt gtccattgct tttttcaaca tacttttggc
    14461 tgtttctcga taaacgacat ttccaattgt cttcgcctca ctttggcgat aatcgatggt
    14521 cgttgccact gccaacacta acaacgatgc tccaatttta ctgattttcc ttgtcacact
    14581 tcttcctcct tgttttacat aaacccgtca acattccatt cctaaactca aacaatgacc
    14641 cttcaaaggt ggagatatag gaacaaatta aagaaatcat gcaataaatc caagaaggtt
    14701 ggttttagaa caaaaaaaga gtctcctttt tggggagact ctttgttaac tatctaaaaa
    14761 ggttggctct tctcacttca ctcataatgt gtccaggcag aataaatttc tacaacttta
    14821 ttttcctcat caactttgta aaccactcga tgctgtctat tcagcctgcg tgagtatctg
    14881 ccttcatgtg taggtctcag cttttcaaaa gactgcgtgg gcatatatgg atcttccttc
    14941 aatgtctgaa tcacttcttc aaattgtttc tttaaattcg tttgcttgat ttttcttaaa
    15001 tccactttcg cagagttttt gattgcgact gtatagttac tcatcaaaga gcttcccaat
    15061 caatatcatc gatattcgta aagctactgt cgtctttttc gcggtctcgt actttatcta
    15121 aagtacctgt ttgctcaaga aaaagggttt cttgaatcgc tctccagtct tccagcccaa
    15181 tcaatacagc attgtttcca ctacgatcac taataatctc gatttcagta tgattttcat
    15241 ttacctcttt caataactga taaaaatttt tacgagcagt gctaggattc atcgttgtat
    15301 tagccattgt ctctcctcct ttttctgata taattatagc gtacttgatt aagtacgtca
    15361 aaaaaataca ataaagcact taaattcagc aaacttttcc tcttttttac atagagaaaa
    15421 agaccccttt ttagggagga tctttgtcca cgctcacttc ttactccttt acgactagcg
    15481 gtagccaaac gtaaagtaat tggtaacaac gtatcatctt tagcaaaggt cgaatccaaa
    15541 gcctgtgagt ctatgcaaca acaccaatac acgaaggttc ctcgttgcag tgtgacttga
    15601 ttgatatctt gaataacctg aggatacgca cgaaagattt gtaacggtta ttcaaaactg
    15661 attttggccg tcaagtcttc tactgcctca aaaatgattg cctctttcgt ctcctgtcat
    15721 tcatgttcac tatcgatttg atacttgctt agaccgttgg gtttgtgaat caccaattaa
    15781 aaatggcact gagttatggt aacaaaaaat ggtcacttga cgaggctgag attcctactt
    15841 atgaagacac atggcactta agagtcgagg taaaggaaga agctgaaaat ataggaggct
    15901 gtacattatt tggcaaagga ttcggaaatt atgatcaaga catcaaaatc aaaatgtttt
    15961 acagctaaat aggaagaata ataacatttc atacgctgtt cccatcttta atggcttata
    16021 gagggcacct ttagctgaga ataagacaaa acagaccctc tagcttcaat taagagctag
    16081 agggtctgtt tttgatttta aaacttggtt tatttcttca aatggtagct ataggtgctg
    16141 acaacgatat tttcacgcca agacaatcgc aatcttaacc gcaaacttgt ttggttatgg
    16201 agaatattct gccagcgtct gtttggtaca aattgaggaa tcaacacagt agttgtatag
    16261 ttttgtttcg ctgcattttt acttacgata tctacataac ggataattgg attttcaatc
    16321 gagcgataag aagagtggac gattgaaaaa cggacatctg ggaaatgctt tttaaattct
    16381 gcttcgattt ctttttcttt ttcgacatct tcgtctagcg aaacatgcat cgcaacgaca
    16441 taatcaccga tcgaacgtgc gtaattcaac gcaccgatat ttacccgtgt cacattcccg
    16501 actaatacaa gaacggtatt cccgtcataa tcatgtagtt ttgcatcatt ttctaaacga
    16561 agctgttctg ctactttttt ataatgatca tggatcttat aaaaaatgaa cataacgatt
    16621 ggcataatga tgaagaaagg ccaaatgtcc cctaaccgat agacaaacaa aatcgcaatg
    16681 attgcatatg agatgaacgc acccgtaata ttggcaatcg atttgcttaa ccatcttttt
    16741 ccttcttttt tccatttgac gaccatccct gtttgagata aagcaaatgg aatgaacacg
    16801 ccgatagagt ataacggaat caagcgttct gttgagccat ggaaaataaa cagcaatacg
    16861 atcgaaccta gcgctagtgt gataatccca ttggaatagc ctagtcgatc cccacgatct
    16921 tgatacatgt gaggcatgaa tttatctttt gccagattgt atgcaagaac tggaaaagca
    16981 gaaaaaccgg tgttagcagc aactgctaaa atcagcgctg tagcaaattg aaggacgtaa
    17041 tacaaaatac catgtccaaa gacagcttta ccaatttgag acaaaacagt gacttctttt
    17101 tcaggaacga tcccatacca atagttgata aatgtgatcc ccacgaagaa gaaacctaag
    17161 atcaatgcca tcatcgtcaa tgtagcagcg gcattttttg ctcttggctt cttaaagaat
    17221 ggtacagcat tactaatcgc ctccacccca gttaaagagg aagaaccaga agaaaatgct
    17281 cgtaaaatca aagcgataga aacacccggc acagccgctc ctggaagtgc agtagcttgc
    17341 aatggcacag cacctgtcac gatattatat aaaccaacaa cgatcagtaa cgagatcaca
    17401 aggataaatg tgtacaccgg aaataatagg aacgatgcag attccctcag cccacgaaga
    17461 ttcagcatca tcagtagcaa aacgattgtc acagaaatag cgacttgatg accgtagagt
    17521 gctggcaccg ctgatgtgat cgcttcagca cctgctgaga cagatactgc tactgtcaac
    17581 atgtagtcga tcaataaaga gccaccggaa atcaagccag cattctttcc aagattctca
    17641 ctgctgacga catatgctcc cccgccatga ggataagcat ggatgatttg acgatatgat
    17701 agcgttaatg aaatcaataa aataataaca aaagcggcaa tgggtagcga ataccagatg
    17761 gctgcagcag acaaagcgac taaaacgaca acgatttgtt ccgtaccata tgcaatagat
    17821 gataacgcat cagacgacaa taatgccaaa gcagcaaatc gggttaattt gtgctcatca
    17881 ttttcagcag attttaaagg cttacctact aacaaccttt ttaagtaatc caatttctaa
    17941 actcctttac acacaatttt acttcaagtt ttatagtcga aaatttatag taaacaagat
    18001 gttatagtac gctcactgac cttaaaagtc aataaacttt aagaaaataa ttggaaaaaa
    18061 acagaaaaat atcaagcgct ttttcaaacg ctttaataca gcaaaaatct aacatttttt
    18121 tatgggcttt ttctttgaat tctataataa aaggatagaa cttgacttag aaaatcaagt
    18181 tctatccttt ttgatatctt aacttttgga agagagatgt aaggctgctt tctacccatc
    18241 attcttacta ctcgaagcat agcgcagttg tcacaacctc ttgataaacg gtgtttaaaa
    18301 gcttgcatct gcggtaataa gctcaaccaa attaaaaaca taagaagctg tttttatttg
    18361 gtcgttctta ttacttgatg cagagcagct tttttacaac ctcttggtac acggtgttca
    18421 atcagctgac cctcggtatt agctcaaaaa aacggcaaaa tatgaggaac tatttttcca
    18481 tttttttctc taatactcag gtcaaaacac tgatttcaca acctcttttt ttaatgaaaa
    18541 atatggctct catgcgccgc ttctttgaat ttcgtcattt tttcttcgat gaacggatag
    18601 attgccgttc ctacgattcc aaagacaaca aacaaaccga tcatgatcca gattgctttc
    18661 gtagcatttg gccaataaat tcctcctgca gattcccgta acaagtttac cgcatgagta
    18721 aatggcaaga acggattgat catttggaag aatttccctg agacttggat cggatagttc
    18781 ccgcctccgc cagagatcga cagtactaag atgataatag cgatcccttt accgacatta
    18841 tcgaataatg cagccaagac atagacgatc atcatgaacg ctaaggcgat caagacagca
    18901 aatgacacgc tgtagaccgg attttggaca tctactccta gtaagaaaat attccctaat
    18961 gtaacgatca agctttgcgc aatcgccatt gtcaaaaatg tcagcatacg agcaacgaat
    19021 tgttctcgtt tcgtaaaatt gtttcggtct ttctttccta aatagtattc tgtcgtagca
    19081 acacttgaaa gaagaacagc gccgacccac agacatagtg cagtataaaa cggggtgcta
    19141 gctgaaccgt tatttgcgat tggataaagc gcattggttt gtagctcaac aggttgtgta
    19201 aagaagtcac tttcttttgt tgcgtctagt ttcaataatt tgatgacttc gcctagatcg
    19261 acttcttgtt cgccttttcg gatcgcgtct gctgcttttt ggataccagc tttgatattt
    19321 ggccagtcat tgttgatcaa gtccgcagca gcgttcacag ctgtttcgac ttctggcatt
    19381 ttttcattta ctgttgtcaa tgtaccggtg atttcatttt ttagtgctgg ccaatcattt
    19441 tggataaaat cagcggccaa tcctaatttt tgctgaatga tcggtaattc attgttgtat
    19501 aggtctgccc cttcattgat gccattgacg atggtatcca tatttccatt cagcattgta
    19561 ttggcatcat ggatttcttg tccaattgca ggcatttctt tttgatattt ttctaaaatt
    19621 gccactgcat tcgttacagt tgctttcgtt gagctgagaa gcgaatcaaa gtcgatctgg
    19681 tccgctttgc tcagtgcgcc ttgtgcagtc ccaatcgtat cgatgacttg gtctagtaga
    19741 gaagtgacag tggaactgat ttgacctgta ttgataccag caatgatgcc attgatatta
    19801 ttaacaacgg catcaatttg atctagcaat tcatcaatag ccttcgtgtc ttcattttga
    19861 acagctgtgt tcaaagcaga taggcggttt tgcagattgc ttagcaaggg ttttaattga
    19921 tttagctgat caataattgg ctgtaatttc gtatttccag cacttgtttg caatttagtc
    19981 aggaactcga ccagtttatc gattgcattt tgttgttgag atattccgtc aataaagccg
    20041 ttcaatacat tgctgatgtt tttcttttca tcatcagtca gcttaccatc ttcaatagct
    20101 gttcttacag tatctattaa cgaacctgtc gttgttgcca cttgtccaat tgacttcaat
    20161 gtaacatcta cactgtttgt gatgcttggt atcgcatctt tcagctgaga ggcacctgat
    20221 tttgtttggt ttgctagatc acttgcctga ttttctaaat ttttcacatc tggcaagata
    20281 tcttgtactt gttggatgat cgtcaagcct tgttttgctt catcgattcc ttggttcatt
    20341 gtctcttgga tcgaagcaaa atcgccgtcg atctctgcta gttgcttacc ggcattttgg
    20401 atctctggga ttttttcttg caaatcaagg atgatttttg cttgatcttt caactcaggc
    20461 attttgtcat tcaatgcaac gactttttca cccatctcat ctactttagg gatgtaatcc
    20521 acgaattcat ttgctttatt cagtttttcc ttgatttcag gtagttgact ttgtaattcg
    20581 aggacttgtt ttgtgtagcc gtcgatcgtg tccaaatttt catctgttga taaaatcata
    20641 tctttaactt tattgatact tactaggttc gtatcgatgt cgtaacctat ctcattgaat
    20701 actttcaata aagtcgaact ggctgttttg ataaattcat ttgtgatttg cgattggatc
    20761 gaacttgctc ctttatcggt gattttcggt gcaatcgcat tgattttttc atttaccgta
    20821 tattcgattt ttggtttctt gatatcacca ctagtaaaac tcagcagatc ttctgagaaa
    20881 tcctttggca agtaaatacc tgcgtaatac tttccggaac ggactccgtc ttctaattgt
    20941 tcttttgaat caacgaattg ccatcctaat tgtttatttt tatgaagcga ttcgatgact
    21001 tgctccccaa tggccacttc tttaccttga aactctgctg gcttgtctgc actgtaaaca
    21061 gcaattggca gctctccagt atttccatat ggatcccata atgctttgat gttaaaccac
    21121 gcatatagcg aagggatgat catgatcgcg atgatcagaa gtgttgcaat cgggtttttg
    21181 aaaatccgtt tccagtcaag caaatataat cgaagcgtat ttttgattga ctgcatagtt
    21241 ctcccccttc ttcttttttc agctgaatta ctttaccatg tatttcatac ttttttcaat
    21301 cggctttttt caaaaaagtc gaatttttgg acatatcacg gcaattgtct cattgtaatc
    21361 tcttacatat tgagaaataa ttaaggatta cagcctttac tttatcatga aataaaaggg
    21421 aaagataatt ttatgccaaa gtttttatct attatacgta tacgcaaaaa agctaaaaca
    21481 ttttttgtct ttgcccctac aaaaatgttt cagctttttt cgttttttat tcctgtattt
    21541 cttatttttc gaatgacagg atgattttcc cagcaggagg atgtccttca actagctgat
    21601 gtgcttggat gacatgctta agtgaagcag acagattcat tgaaataaaa acatgaaagg
    21661 ctcctttttg gtaggctttg attatgccag caaaggcttc tgcatctaga tattcctttc
    21721 ttggaacaaa cgattcataa aagccttcct ttttttgccg caaatctaga tctgggaggt
    21781 catttaatgc aacatacctg ccgcctggtt tcatgatctg gatgccggtt tctcctttga
    21841 tacttccttt cgtcgcatcg attacaaggt ctgcctgatc agcaaattgc agacctggat
    21901 ttgttttatc ataagcagca aatgctgaag ctcctaattt ttttaccttt tcctcatttt
    21961 tactggatgc actggttaag attcggattc ccttttcatg gagaagctgg atcagacttg
    22021 acccgaccgc acctgatgct cctagtatca ttacagtatc tgtcggctgg atttccgtca
    22081 aatggttgat tagattataa gccgtaattc ctggcgtgac cattccggct gcttcttccc
    22141 aactcatttt atctggaatt tttgctactt ttgctgatgg caacacgact tcttctccgt
    22201 aagtcccgcc gactgcatgg acagctactc gatcacctac atgaacagtt gtgacatctg
    22261 aaccaatctc tgtcacaata ccagcgccat cattacctgg tacataaggg aatttcaatg
    22321 ttcgtatctc tttcatttct cctaaacgca aggcaacatc ataaggattc acactgaatg
    22381 cttttatttc tacacgaaca tgtccagaac cgacttctct gggatgagca tcgatttctt
    22441 caaaaacatc ttgtgcttct ccgtaaccgt taattgcaaa tcttcgcatg gtcaccatct
    22501 ccctttttct ttaagtttac gtttatgtct ttattttgac aaaaaaaatg tcttttcgtt
    22561 ttggcgcatg attcaaaaca aaatagttgt cttttttcgc gtaacgtgtt aaattattta
    22621 tctaaaagcg taaagattac gatttacgct aataaaaaat aattggagga atttgttgat
    22681 ggctaaaaaa tcaaagattg ccaaagcaaa aaaacagcaa gaaacgattg aacgctatgc
    22741 tgctttacgc caggaattaa aagcgcaaaa agattacgaa ggcttgcgta aacttccttt
    22801 agatgctcgt ccagaacgat tgaaaaatcg tgatttaatc gatggacgcc ctcgcggata
    22861 catgcgtaaa ttcgggatgt cccgtataaa attccgtgaa ttagcacata aaggtttgat
    22921 tccaggagta aaaaaagcca gctggtaatc caagtctggc tgtaatgtaa aggaggaggg
    22981 cgcatggacc actccttgga tcatcaaaaa agatacgttc gcttcttcta gcagaaatgc
    23041 tggtactaga agcagacgta tcttttttta cgcacagctg gtcctttttt atatgtaaag
    23101 gctgcatggt tacttcgcta tatttattta gtaacaggag tcagtgcttc gatacccaca
    23161 ctaattttca atgctcggtc aacttctgcc ataatgggtc gatccaaatg gcagaccttt
    23221 tctttcaatc ttgatttatc gatcgttctg atctgctcca acaggataac ggagtctctt
    23281 tctattcctg ttccagtagc tttgatccca atgtgagtcg gaagcttagg tttagccatt
    23341 tttgccgtta tggccgcaac aatgatcgtc gggctaaaat ggttacctag attattttga
    23401 ataaccaaaa ctgggcgtgt tccgccttgc tccgatccca cgactggaga aagatcagca
    23461 aaataaatat ctcctctttt taccatagga tcctccttat tcttgatatt ctcttggtat
    23521 ccgctgtcct aatccgcaag ccacttcata gtggatcgta cctaattgat ctgctatatc
    23581 ctgcatagtg atttctttgt ctgcattttt gccgataagc gtcacttttg ttccgacagg
    23641 aaattcttga ggcaatcgga tcatcagttg atccatacat acacgcccaa tcgtttcaca
    23701 gtagttccct tctaccaata gagaaaaacc ctgcatcttt cgtggccagc catctgcata
    23761 accgatcggt atcgttccga tccactctgc ttcaggagtg atatatgttt ctccatagcc
    23821 gattccttca cctgctggga gttttttgac ttgaatcaat tcagaaacca gctcaagtgc
    23881 tggctgcaat ggataaactt ccggtagtgc gtgcccagag ggattaagtc cgtacattgc
    23941 tactccataa cgaatcatat tgccgattgt ttcatcatgc cataaagccg ttgcactatt
    24001 gctgacatgt acatatcgag gaagttcggg aagttttttc agcacttcta taaagcgttc
    24061 tttttgcaga ttccaatatg tatcatctgc ctgatctgct gtagaaaaat gggtaaataa
    24121 accttcccat tctaatacac gactttcttt gatgaatgca gctgcctctt ttacttcttc
    24181 aggtgtacaa aatccgatac gacccatccc agtgtctgct tttagatgaa tcgaaagagg
    24241 cgtctctagc ttacttttct ctaaaacagc agctgctgct tgcaaccatt cccgtgtacc
    24301 tgcagttact gataaatcat gagcaacagc tacagtcagt gcgtcgtaag gaaccatatt
    24361 caagataagg atgggctgag taaatccagc ttctctcaac tcgactcctt catctaaatt
    24421 tgaaacacaa aagcccgaag ctccacctgc aactgctgcc tcagctgttt caatagctcc
    24481 atgaccgtat ccgttcgctt ttactactgc aaacaattct tttccttgcg gaagtcttgc
    24541 aacttcattt gctacatttt cagttatagc ttttttatgt atcactgctt tcgttgggcg
    24601 gtgccaagcg acaaccatcg tttttccttc tttctagtct tccaaaataa tttgtgcaaa
    24661 agctgtttca tttgtatgag taatactgac ccatacattg ccttcatgag gtgaacgcgt
    24721 cacaacaggc tgaccatttt cattttttaa aatctcgaca tcttgaaagg taacttttcc
    24781 gatcccagtt ccccaagctt tagagaaagc ctctttgcaa gcgtaacgcc cgcctaaaaa
    24841 ttctacttgg cgatgaaaag gcaaggactg gaatagtttc atttcatcag aggtcaagat
    24901 tcgtgcaatg aattttggtt tttcttcgat cagccgagtg atcctaggaa gttcgactgc
    24961 atcgatccca attcctttta tcatatgctt ttctcttttc aataaattta gaacactctc
    25021 attctaccaa attataacca ttttgccaca aataagtcca caaataacaa aaatgaaagt
    25081 ttctcttaaa aaagagaaac tttcatttta tgtttaatcg ttatttgaac ggattacaaa
    25141 tccgcgtttt ttatcattgt gacgtttacc gccatctttt tggctgttat tatttttgct
    25201 ataaccgcct tttgatttgt ttccacgata attaccgccg tcacgacgat tacggttgtt
    25261 tccgccacca cgtttgccat ttttattgta tccttttttc tgcattggca atgggcgttc
    25321 tggtgtgatc ttcactggca ctgcatcagc tggatctttt gctgtcgttt ttagcaaaag
    25381 tgcaactaaa tcttgtgcag aatattcttc taataattta tctgctgttt gcaggtattt
    25441 atctagacca ttttctgcaa gttttgtttc gatttgttca actgcagcac ctaattgacc
    25501 tttgaatgct tctttttcgg ttggtggacg taaagtcgtc atccgttttt tcgtcaagtt
    25561 ttcaatcaca tgcaagtagt ccatttcatt tggtgtaacg aaagtcacag acataccgcc
    25621 ttttccggca cggcctgtac gtccgatacg gtgaacgtag ctttctggat cttgagggat
    25681 atcatagttg tacacatgag tgacacctga aatatctaat ccacgtgcag caacgtctgt
    25741 cgctacaagg atatctaaat gaccgctctt aaatgaacgc aatacgctca ttcgtttttg
    25801 ttgagacaaa tcgccatgga ttccttctgc acggtaaccg cgtgcttcta atccgcgtgc
    25861 caattcgtct acacggcgtt ttgtacgtcc gaagacgatt gttaattcag gtgtttgaac
    25921 atcaaacaag cgagtcatga tatcgaattt ttcgtattct tttgcgcgga catagtattg
    25981 atcgatcaag tcagctgtca tttctttcgc tttgatcttc acatgatgtg gatttttcat
    26041 gaatttaacg ccaatattct tgatagctgg cggcatcgtt gctgagaaaa gtaatgtttg
    26101 tctttgatca ggaacttgtg aaatgatttt ttcgatatct tccaagaagc ccatattcaa
    26161 catttcatct gcttcatcca aaactaatgt ttgaacggtt ccaagtttca atgtgtggcg
    26221 gttaatgtgg tcaagcatac gtcctggtgt acccacaacg atatgtggac gatctttcaa
    26281 gccacggatc tgacggccaa tatctgctcc gccgtaaacg gcttgtacac gtactttttt
    26341 gtcgcgccct aaacgatata attcttcttg tgtttggata gctaattcac gtgttggtgc
    26401 gataactaaa ccttgtaatt cgtgacgatc tggatcgatt ttttctaaca ttggtaatcc
    26461 aaatgcagct gttttccctg tacctgtctg tgcttgtcca ataacgtctt ttccagctaa
    26521 tgctagtgga atcgtttctg cttggatagg cgttgcttct tcaaaaccag cgcgttcgac
    26581 tgatttcaac aattctggtg ataattctag ttctttaaat ttcaaatgaa tcctcctata
    26641 tggttgttaa ctgaggatgt agcttttttg ctaccccgtc gatttgttcg gtcaaagtgt
    26701 attgtttctt tttgacagtg gccacgcacg tttttatcca ttcttagccc ctgtggcacc
    26761 accgaaaaat cactttgcga agtttaggca ttagaaaagc caaacgggtc gcgttcagct
    26821 ttatcattat tatgacatct ggcttcaaca agttgtttct atggcaaaac cagtccaatt
    26881 tctcttcatc tttcggcaat aggttattct aacatagttt ttcgttttct gcaagtttac
    26941 agatttttat ttcatttgct gaagttgttc taccacttca aataagccca tgctgttgct
    27001 gccttttagc ataatactat ctgttgctgc aagattttgt ttgatagcat caatcaattt
    27061 attcttttct ttttcaaaat agaacacagg tagttggggg tatttttggt tcaattcttc
    27121 ttttagtgca tgcatttgtt ccccataaag gaaaatcatg gcgaatttct caggatcgat
    27181 atgttcactc atttgcgcat gcatatttaa agactctttc cctaattcca gcatatctgc
    27241 taacacagcg attctgcgtc cttttgttgg cagattttta aaagtatcta ataccagtcc
    27301 catggctgtt ggatttgcat tgtagacatc gctcaaaata gctgcaccat ttcctgccgt
    27361 tagccattcg gttctgtttt gagtgataga aacatgggcg agcccttggc gtatctcagg
    27421 tatggacagt ccaaagaagc gcccgatcgt atacgcaatc aaagcattcg ttacattata
    27481 acttccaggc agcgggatcg taaatgtttc tccttctact acaaaatcgg tttgtgcttt
    27541 tccttttgct gtcacttccg catgaacatc gccatttcca ataccgaatg ttgtgactgt
    27601 ttgtactaat gttgccgtta aaggtgtcag caacggttca tctgcgggca caacgagtaa
    27661 tccgtctgat acaagtccgt cagtgatttc cattttggct ttagcgattc cttctcgcga
    27721 cccaagattt tctatgtgtg cttcaccgat cattgtgatt gctgcagctt ttggttgagc
    27781 cataagtgaa agttccgtga tttcattggc gtgatccatg cccatttcca aaacgatctt
    27841 ttctgtatct tggggcatgt gcaaaatcgt gtaaggaaga ccaatattat tgttgtaatt
    27901 tccttgcgtc ttatatgttt tgtatttttc agacaagaca gacgcggtta gatctttcgt
    27961 ggtggtttta ccattgcttc ctgtaattgc aacgacttct gcgcctactt tttccaagta
    28021 ataggttgcc aattgctgca tggctttcaa aggatctgct acaggaataa ctggaaaatt
    28081 ttttggagct tgttcaacag gcaagctcca aaatgaagca gatgctccgt ttgtgatcgc
    28141 ttgctggata aattcatgtc catctcgcgt accagcaaga ggaacgaata aacttccttc
    28201 ggttatcttc cggctgtcaa attcgacatt ggtaatcttt gtcagtgcag agcattcgct
    28261 gcccacggct tgtgcaattt cttgtattgt tagattcatt gagatctctc ctaaaaaagg
    28321 ttgtgaaaaa agcgtttggc ctaaacggcg ggttcgcatg actctcactt ccaagtaaat
    28381 ttctctattc gtatttagaa gctagaatga acgcggttac gcaatcactc cagcctcttc
    28441 tttatttctc tttattcatt tttttcaaaa aaagattgac gctgatggta tcgattcatt
    28501 cctaactgga tcagttcttc aatcaaatca ccgtatttca agcccatatt ttcccataag
    28561 agtgggtaca tactgaactc cgtaaatcct ggcatagagt ttaattcatt caggaataat
    28621 tcatttttat ttgtcaaaaa gaaatcgcac cggctcaatc cgcttccacc taacatcgtg
    28681 taagctaact tcgcgtactc ttgcgctttt tgataaactt cttctggcac ttcggctgga
    28741 atctgcattt cgattttatt attgatatat tttgcttcat aatcatagaa tgctacgtct
    28801 tttacgactt caccaggcaa agtcgtccga acgtcttcat ttcctaatac agcaacttcg
    28861 atttcgcgcg cttcaattcc ttgttcaacg attgctcgag aatcatactg ataggctgtt
    28921 gctaaagcat tttgcagctc ttctcggttt tctgcttttg taatgccgac actagaaccc
    28981 atattcgccg gtttgacaaa catcggataa agcaaagaac cttcacattg atcaaatact
    29041 tttttaggat tttctttcca ttgattctta agtactggta cataaggaac ttgcggcaca
    29101 ccagcagctt gtaaaatata cttggtcatg attttatcca tggcacatgc actggtcaat
    29161 acgcctgcgc cgacataagg catattcaat gtctctaaga agccttggat cgttccatct
    29221 tccccgtttg gcccatgtaa aactggaaaa acgatggctc cttcttcttt gatttcgccc
    29281 ggattgatca cttttcctgt aaagccttcc tctgtctgtc cacttgggtc ccatgaaaga
    29341 tgcaagacat ctttgctggc aggtttttct gttagtaatg gacctttgac ccattgtcct
    29401 tcttttgtaa taaatacgag ttgaacttgg taataattat aataaatggc atttaaaact
    29461 gaaaatgcgg aaagaatgga cacttcatgc tctgcgctgc gtccgccata tagtaaagta
    29521 atcttcaaaa gattgtcctc ctgtattcta aatcgttcag tgatttactc tcatatttta
    29581 gcacaaaaca aaaataaacg aataacttat ttataaaaaa acgagccagc ttctaaaaga
    29641 acgagcgtca tttatttttt gtcagctaga ttatttgtcc cgttttttat aaaaagttat
    29701 gataaagaaa aggagggatg atgatggcgc aaacaaatcc acgcagccgc ttggcagaaa
    29761 tcattcgagt gttcatcaat tacaatgtag tgccaaactt tgtacagcaa aaaaatcccg
    29821 aacaggtaaa aaaagccttt gaagaactag gccccacctt catcaagata ggacagatgc
    29881 tttctgttcg agaagatttg ctttcttctg ccttcactca aacattcaaa acattacaag
    29941 atagtgtacc tagcgacaca ttttcaacgg tcaaaaagac gatcgaaaca gaactttctc
    30001 tttcattatc agatatattc gatgattttt caaaatcgcc ttttgcctct gcttctatgg
    30061 ggcaggctca tcgtgccaag ctgaagaacg gtgacgcggt agtcgttaag atccaacacc
    30121 ctaacatcgc cgaagagatc cgacttgatc ttcaactatt tgaacgagcg atccctttga
    30181 tcaaatacat tcctgaaact agcgtagttg atctaaaagg ggtactccaa gaagtaaaac
    30241 gttccttgat caatgaaatg gacttcttaa aagaaagtca aaatggcgaa caattctatc
    30301 aaaagaacaa tggctggaaa gagatccgca gccccaagat ttatgacgct ttttgttcga
    30361 aaaaagtgat cgtgatggaa gaaatgtctg gtaaaaactt gaatcattta atgaacgccg
    30421 aaaacaaaac tgaaactttt atcactggaa ttcaaaacaa gcagctgaaa caagaagttg
    30481 caaagctttt agttgagaac tttatgaaac aggtgtttga tgatggtttt ttccatgctg
    30541 atcctcatcc agggaatctg ctattccatg tactaacaaa agaagaacag acacaagcta
    30601 gccgaaaaac tgaaacagtc catgaaaaag agttcggttc ctttgctttt cgagcctcca
    30661 cttctgcaga agaccctgtt gcgccatata ccatcaacta catcgatttt ggtatgatgg
    30721 ggcatctttc tgcaggactt aggcaaaaac tcacacaagc cgttttagcg ctgtatacga
    30781 aagatgctta tcgaatcgaa aaagcggtcc ttcgactttg tcagcaagaa ggctcgtttg
    30841 atgaaagtcg gttccaccaa gaactgacaa gttttcttga acagtattat gattctccta
    30901 ttgatgaaat caacttgcaa gaagtattca cacatgtcgt gacgatttgt catcaaaata
    30961 atctgcagtt cgatcgtgat atcacgcttt tgctgaaagc atttgggaca ttagaagggg
    31021 tgatccgcgt cctcgatcct gaagtttccc tcatggaagt cgcttcgcct tttgctcaac
    31081 attattttct cactcatctg gatgtagaag atacattgaa acaaagcgga ttagacttat
    31141 tggaagggat gaaggctgcg cctaagatcc ctcaacagct ccaccatcta ttagaaatgt
    31201 ggacttcggg acaaggaaaa gtcaatttgg aattgaaaaa gcaagacaaa ttattgagca
    31261 ggatcgaaag tatgatcaat cggcttgttt tcggtatgat tttagctgca ttgatcgtag
    31321 ggtcctccct gcttgtccaa gcagcacctg tagaaaacgc agaggtcgtt tccttattag
    31381 ggatatttac gtatgctatt gccgcattcg tcattatttt tttggcaatc gatgcattga
    31441 tccaaatgta taagaagagg aaaaagtaga aaaaggttgt gacagaaaga atcagcttca
    31501 agaaataaga aggggtttta cataaattgt ttctcaaatt tttgtgaaaa ttcggcttat
    31561 ttttcgaaga ggctacttct gaaacaccga gaataaaaaa tgtgaaaaag ctgttctgca
    31621 cccagtaata agaacaatca aaaagggaac atggaacaca tttatcctgt ttccctgttc
    31681 cctttttgat gtattcgagc ataaataaaa taccttcgtt acctactatc ttctgtactt
    31741 ggtaaacctt agtcaattgc cttttttaac gcttgacgaa aagacatatg atctttctcc
    31801 gtaaagggtt ttggaccctt tgtccttatg ccagcttttc ttaactttcc actatgataa
    31861 cgttgttcta gaagcgtgcc gatattcgct tcgtcaaatt cttttccaga gtgatggaac
    31921 actcgcacac ccttcggcaa tacaagtgaa gctaaaccat aatcttgcgt gatcaaaaag
    31981 tcattcttct taaccatacc gacgatttta taatccgcac tatcagctcc gcggtctacg
    32041 tagacgattt ggacatgatt agcgtattct ttggtcgtat aatggtccac actggtcacg
    32101 ataaccacgt caagaccata ggattctcct aattttatga catcttcttt tactggagaa
    32161 ccatctccat caatgaatag cctcattctt tttcgccttc ttccataaat gataaacagt
    32221 tactaatccg ctcagtaaaa gaccaacatt gatccatttt gccaagataa gcagttgtac
    32281 actttctatc ggcactgatt catggttcag cgtgatcaat aatagatgga ttggctctcc
    32341 catttctttt gctaaaacaa acaaaagcgt catcaataaa aactggtgga tcacactccc
    32401 tttattttga gtagtatact tgacaacgat ccggcgatcc attggaatag ctgtatcagt
    32461 ttgataatat tccttattta gccagctgcc tgttactacg tgccagaaac taagcagaaa
    32521 gacacctatc gcaaaaccat ttggaatcaa gaggaccaat aaagaagaac tcagtccaag
    32581 caattgcata gccaatggag accatgttaa acgtttcaaa atccatggtc cgactatttt
    32641 tgctgcaatc aagcctgctg cataaggcaa atacataaaa atcgaaagtt tttctaatcc
    32701 gtacagtatg ccaacataaa aactgctaaa taaaaaaagg aaattcccta gcattccatt
    32761 tagaaaagta aacagattta gccagcttgg caacttccat tccttcttct ggtgtcctaa
    32821 aacaaacacg aacaagatga acagcagcaa gaaaccataa atagcaagat caaaaagcct
    32881 ttcatcgaat aacaatcggg catttctcaa aagaaacaat aagccaaaga atatcaaaaa
    32941 taaaacaagc tctcgcgtag ctaccagatt tcttttgatg tctttgaaat ccagttcgta
    33001 acgcggataa tgactaaccg tatggtaggc catgacgtaa aaaagtgtat aaatagtaaa
    33061 gcttgctgca atctgagtcg gtgcaggcaa ctcaatcgct tgatacagga gaaatagcca
    33121 gatagctgca aataagtact ttttcccatc catattgata aaaccttgcg tcttttcgtg
    33181 aaaattgacc gtggtattag caggtacaag ccatgctgca ctcagcccta gcaaaacact
    33241 tgaaaaataa aataaaggaa aataaaatac gcctaatatt ccaagcaatg aaccagcacc
    33301 accaatcagc agagcgatca tcagcaacgt gtaactatct agaccaaatc gtagactgtt
    33361 gactaaaaat agtccagtca tccgaaaggc ataaaacagc gtaaatggca aaatcgtcag
    33421 ccaattatgc gagtctgtta gtcccaaaaa taaaagataa ggaataaaaa taaccgtgtt
    33481 acttaagata aagggcgttg tttgtgtaaa attacgccca aatcgtttga gtttttcgaa
    33541 catgacaatg gctccttaaa cagtcttata actaatctgc tcttcgattt tagcattaaa
    33601 ggggaaataa accaatttta cagaatatat tcttgtaaaa aaaaatacag aaagaagcat
    33661 aagcttcttt ctgcattttt acggtacttg attactcaag cagacaagcc cttctccaca
    33721 aaagtcttgc ccgacacccc tgcatccggc aggtgataaa gatagaaatc aattatcctg
    33781 tgcctccaaa atcaattagg agctctgtaa accagagtcc ttctcgaccc gtcgcataaa
    33841 tttactttaa cacagttcct atgtttatgc gagagctttt ttcattttat aatcgaccat
    33901 ttgaaatcct tgaccgatat ctgaaataag ttcttctgta atctcaaatc cttcatgctt
    33961 ataaacctcg attgcttgat gattcccctg attcactcgc aaaaagatct ctctttcctt
    34021 tgtttgcgca gcaagttctt cataccagcg aaaaactgaa gaagtcaatc cttgaccacg
    34081 tactttattt agcaaatata atttacttaa ataaattttt ccatttatct cttcataagc
    34141 agtgtaaccg acagtctttt cttcgctttt taataaaaag taggacacac cttctgtcag
    34201 ttctttttga atctgttttt ttgactgata agttttcagc atgtaatcca cttgtttttg
    34261 accaatgatc ggcacaaaag cttccggcca tacttcttgt atgactgcca tcagctcatc
    34321 cagttcattt tctgttactt ttattttttc catacaccca cgtccttttt tacattataa
    34381 atgaccttgc gcttgatgga ataaaaagag catgatcatg ctatacacac ccaccgacca
    34441 tggtttcaag aaaatcacaa tctgcataaa ttccctaaaa gataatttcg tcaaaccagc
    34501 tactagacag atcaagtcgt ctggcgcaaa gggaagcagc aaggtaacaa ctagtacttt
    34561 tttaatatct ttcgtttttc ttgtcagcaa ttcatcaaat ttctgatact tttttggcga
    34621 taaaataagc tggacaaagg ctacgccata gtaacggaca agcaaaaatc cgattgcttc
    34681 cccaatcact aggccaatac aactatataa aagcccaaat ccattgccaa acatcagcat
    34741 gcccgctact gaggagatcc ctcccggcaa aataggaatg atcacttgga tcacttgcaa
    34801 cagaacaaat atcatcactg catacttgcc aaattgctgg ataaacgctt gcaaagacgt
    34861 gctcgatcga aaaatcccat gatgataagc ataaagaatc aacacaaaga aaaaaaacag
    34921 accaataatg ggcatgatct gaagacattt ttgtaaaact gatccttttt tagacatcta
    34981 tattccccac atcttttttc atttattaaa actgcctcct t
//
LOCUS       DARPZF010000024        34522 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.025, whole genome shotgun sequence.
ACCESSION   DARPZF010000024 DARPZF010000000
VERSION     DARPZF010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34522
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.025"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(133..306)
                     /locus_tag="SLE65_001510"
     CDS             complement(133..306)
                     /locus_tag="SLE65_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8448810.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            754..3116
                     /locus_tag="SLE65_001511"
                     /pseudo
     CDS             754..3116
                     /locus_tag="SLE65_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            3484..4407
                     /gene="truB"
                     /locus_tag="SLE65_001512"
     CDS             3484..4407
                     /gene="truB"
                     /locus_tag="SLE65_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEI8448811.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            4411..5352
                     /gene="ribF"
                     /locus_tag="SLE65_001513"
     CDS             4411..5352
                     /gene="ribF"
                     /locus_tag="SLE65_001513"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HEI8448812.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            5704..6489
                     /locus_tag="SLE65_001514"
     CDS             5704..6489
                     /locus_tag="SLE65_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8448813.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            6502..7353
                     /locus_tag="SLE65_001515"
     CDS             6502..7353
                     /locus_tag="SLE65_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HEI8448814.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(7477..7929)
                     /locus_tag="SLE65_001516"
     CDS             complement(7477..7929)
                     /locus_tag="SLE65_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8448815.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(8394..8762)
                     /locus_tag="SLE65_001517"
     CDS             complement(8394..8762)
                     /locus_tag="SLE65_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HEI8448816.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            8912..9394
                     /locus_tag="SLE65_001518"
     CDS             8912..9394
                     /locus_tag="SLE65_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HEI8448817.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            9431..10441
                     /locus_tag="SLE65_001519"
     CDS             9431..10441
                     /locus_tag="SLE65_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEI8448818.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(10556..11269)
                     /locus_tag="SLE65_001520"
     CDS             complement(10556..11269)
                     /locus_tag="SLE65_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448819.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(11459..12049)
                     /locus_tag="SLE65_001521"
     CDS             complement(11459..12049)
                     /locus_tag="SLE65_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HEI8448820.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            12533..12760
                     /locus_tag="SLE65_001522"
     CDS             12533..12760
                     /locus_tag="SLE65_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HEI8448821.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            12776..13942
                     /locus_tag="SLE65_001523"
     CDS             12776..13942
                     /locus_tag="SLE65_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEI8448822.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            14176..15219
                     /gene="hrcA"
                     /locus_tag="SLE65_001524"
     CDS             14176..15219
                     /gene="hrcA"
                     /locus_tag="SLE65_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEI8448823.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            15313..15876
                     /gene="grpE"
                     /locus_tag="SLE65_001525"
     CDS             15313..15876
                     /gene="grpE"
                     /locus_tag="SLE65_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEI8448824.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            15927..17756
                     /gene="dnaK"
                     /locus_tag="SLE65_001526"
     CDS             15927..17756
                     /gene="dnaK"
                     /locus_tag="SLE65_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEI8448825.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            17907..19073
                     /gene="dnaJ"
                     /locus_tag="SLE65_001527"
     CDS             17907..19073
                     /gene="dnaJ"
                     /locus_tag="SLE65_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEI8448826.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(19155..19820)
                     /locus_tag="SLE65_001528"
     CDS             complement(19155..19820)
                     /locus_tag="SLE65_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8448827.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            19796..19969
                     /locus_tag="SLE65_001529"
     CDS             19796..19969
                     /locus_tag="SLE65_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448828.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(20014..20751)
                     /locus_tag="SLE65_001530"
     CDS             complement(20014..20751)
                     /locus_tag="SLE65_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEI8448829.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(20753..22255)
                     /locus_tag="SLE65_001531"
     CDS             complement(20753..22255)
                     /locus_tag="SLE65_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEI8448830.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            22514..24508
                     /gene="uvrB"
                     /locus_tag="SLE65_001532"
     CDS             22514..24508
                     /gene="uvrB"
                     /locus_tag="SLE65_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HEI8448831.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKEELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            24518..27334
                     /gene="uvrA"
                     /locus_tag="SLE65_001533"
     CDS             24518..27334
                     /gene="uvrA"
                     /locus_tag="SLE65_001533"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEI8448832.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            27597..28862
                     /locus_tag="SLE65_001534"
     CDS             27597..28862
                     /locus_tag="SLE65_001534"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HEI8448833.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            28866..29597
                     /locus_tag="SLE65_001535"
     CDS             28866..29597
                     /locus_tag="SLE65_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HEI8448834.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            29732..30616
                     /gene="rapZ"
                     /locus_tag="SLE65_001536"
     CDS             29732..30616
                     /gene="rapZ"
                     /locus_tag="SLE65_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEI8448835.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            30613..31611
                     /locus_tag="SLE65_001537"
     CDS             30613..31611
                     /locus_tag="SLE65_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEI8448836.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            31645..32580
                     /gene="whiA"
                     /locus_tag="SLE65_001538"
     CDS             31645..32580
                     /gene="whiA"
                     /locus_tag="SLE65_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEI8448837.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            33123..33773
                     /locus_tag="SLE65_001539"
     CDS             33123..33773
                     /locus_tag="SLE65_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448838.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            33960..>34522
                     /locus_tag="SLE65_001540"
     CDS             33960..>34522
                     /locus_tag="SLE65_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HEI8448839.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT        11453 a         5832 c         7324 g         9913 t
ORIGIN      
        1 aaatcagggg ttgcgggatt tttttgtttt cattaagacg tattacctaa gagttccatg
       61 actttagtct tgcggcgtgt cagctaacca aaaaagagaa aaagaaaagt aaaaaattcg
      121 actttctttt ttctagtagt atataaattt ttgcatatag ataaagatca agataccgat
      181 aacggaagct agattgtaat ctattttagt gacagtcagg tatagccaag taactagaag
      241 atcagtggaa cctgcaccat aaaagtttga gtttgtcggt ccgttgacag ttaaaagaaa
      301 aatcacgttg aagttattga tatttccgat tacgccgctt cgatttggtc acgatccaaa
      361 ttttggataa tccctgtaga aattagcata gtagctggga taccaattca catattgaca
      421 aagataacag agacttttac ataaaacgga tcaatcagga aaggaattgc tcgatccagc
      481 cccagttttc cagcaatgtg ttaactggcc cagcgtcatt cagcaaatta tgcatgatga
      541 ggagcgaaat gaactgcgga acagccattg tgataacgac aagttttttg gatcaatgta
      601 aaaaacgtca gcgaaaggaa aaatttcgtg gttttttata cctgttcatt tggctagata
      661 taaaatccaa acaaatgaac agaagtgctt attaggtttc aattgggagt atctgcgcta
      721 gaataagagt aataatgaaa aggagtgtta tgtatggatt attctagtaa agaatacttt
      781 gataaaatga cggcttggtg gcgtgctgct aattatcttt ctgttgggca actttatctt
      841 aaagataacc ccttactgag acgtacactg aaacccgaag atgtcaaaaa acatccaatc
      901 ggtcattggg gaacgattcc tggccaaaat tttatttatg tccatttgaa ccgagtcatc
      961 aataaatatg atttgaacat gttttatatt gaagggccag gacacggcgg acaagtcatg
     1021 gtatcgaatg cttatttaga tggaagttac acagagatct atccagaagt aacggaagat
     1081 gagacaggaa tgcaaaaatt attcaaacga ttttcatttc ctggaggcat tgcttctcat
     1141 gcagcaccag aaacaccagg ttctatccat gaaggcggag agcttggata ctctctttca
     1201 catgcagtcg gagctgtatt agacaatcct gaagtaatct ctgctgtcgt gattggtgat
     1261 ggtgaagcag aaaccggtcc tttagctgga agctggttct caaatgtctt tatcaatcca
     1321 gtgatagatg gagctgtttt accgatcctt catttaaatg gtgcaaaaat agccaaccca
     1381 acgatcttgg cacgtaaatc agatggagaa ttagcaaatt actttaacgg acttggctgg
     1441 gaacctttct ttattgaagg aaatgattca gaaaaattaa atcctgttat ggctgaaaaa
     1501 atggatcaag caatcgagaa aattaaatcc atccaaaaag aagctcgcct gaagacagca
     1561 acagatgtcg tgatgccaaa atggccagta ttgatcgtac gcacaccaaa aggatggacc
     1621 ggtccaaaag aatgggacgg ggaaccaatt gaaggaacct tccgagcaca ccaagtaccg
     1681 attcctgtag atcaagaaca tatggatcat gcagatgctt tactccgttg gctgaaatcc
     1741 tatgaaccag aaaaattatt tgatgcacaa ggacgtattt tagaagaaat cagagaaatc
     1801 gcgcctactg gtgaccaaag aatggcaaaa aatcctatca ccaatggtgg aatcgatcca
     1861 agaccgctta ttatgccaga ttggaaaaaa tatactttgc aatttgaaaa accaggctcc
     1921 gttaaagcag aagatatgac cgaacttggt aaattcgttc gcgagatcat tgagaaaaat
     1981 ccagaaaatt tccgtatatt tggaccagat gaaacaaaat caaaccgatt gaatcaagtt
     2041 ttcaaaacga caaatcgcca atggatggaa aaaatcgaac cagaaaatga tgaatggctt
     2101 tcgccatctg gtcgcgtcat cgacagtcaa ttatcggaac accaagatga agggttctta
     2161 gaagggtacg ttctgactgg acggcatggt tttttgcaag ttacgaatca ttcttgcgag
     2221 tggttgactc tatgttgact cagcacttca aatggatgcg gaaatcacat gacctttctt
     2281 ggcgaaatga ttatccttcg ctaaatctca ttgcaagctc aacagtcttc cagcaagatc
     2341 acaatggata tagccaccaa gatccaggaa tattgacaca tttggcagaa aagaaggcgg
     2401 agttcatccg tgaatatctg cctgcggatg caaatacatt gctcgcagtc atggataaag
     2461 cattccgctc gtcagaaaaa atcaatttga tcatctcttc caaacatccg cgtgctcaat
     2521 tttactcagc agaagaagca gccgtcttag tgaatgaagg cttgaaaatc attgattggg
     2581 cttcgacagc aaaagaggag gaacctgaat tggtcattgc tgctgcagga acggaatcta
     2641 acttagaagc attagcagct gtaactttgc tgctggaaga attcccaaaa ctaaaaattc
     2701 ggttcatcaa tgtcgtagat ttattgaaat tacgtcatcc aagtcaagat ccgcgtgggt
     2761 tgagcgatga agaatttgat caatatttta caaaagacaa accgatctta tttgctttcc
     2821 acggttatga aacattggtc cgcacgattt tctttgatcg tcataaccat catttaatga
     2881 ttcatggcta caaagaaaat ggagatatca cgacaccatt tgacatgcgt gtagtaaatg
     2941 aacttgatcg ttatcatttg gcaaaagacg cagctttaaa aatcaaagga agtcaagcag
     3001 aagattttgc gaaaaaaatg gatcagaaat tacaagaaca tcaaaactat attcgtgaaa
     3061 atggtattga tctgccagaa gtattggatt ggaaatggaa aaatcttgac caataaaatg
     3121 ataaaatcga tcccgcaaaa tagaattttt tacattgatt aagaaactga aaaaataaat
     3181 aaaaaaaacg gaaaaaagac tggaagaatg gccagtcttt tttttcgttt ttgggaagtg
     3241 aaaaccaaac tatttacctg taagccaccc ataaatccaa tcaaatggtg caaagaaaaa
     3301 atcttccatt ctattccctc ctttaaaaaa gcataacatg atttctattt acgtgagcat
     3361 gaattttgtt acgtttttat tgccgaaaaa taaaaaccgt tcattatgat gtcaaattcg
     3421 tcagtaattg atgcaatgtg ttataataat tcagttaaat caaaaatgaa atggagaaaa
     3481 gacatggacg ggttattacc tttatggaaa gaacgcggaa tgacaagtca tgattgcgta
     3541 ttcaaattaa gaaaaatctt acatacgaaa aaaatcggac atgggggtac gcttgaccca
     3601 gacgtagacg gtgtgttgcc catttgtatt ggaaaagcca caaaagttat cgaatatttg
     3661 acagattctg ggaaaatcta tgtaggcgag ataactctag gtttcagtac aacgacggaa
     3721 gatcgatccg gagaacgggt agaaacaaaa ccagtagata tgtctttatc tgaaaaaaaa
     3781 atagatgaag tgatggcttc atttattggt gagatcaccc agataccacc aatgtactca
     3841 gcggtaaaag tcaacggtaa gcggttatat gaatatgccc gcaataatga aacagtggag
     3901 cgtcctgtta gaaaggctca gatttaccgt tttatccgga caagtgaatt gacaagagac
     3961 gaagtgacag gaaccatttc ttggcgcttc gaagtagaat gcgggaaagg aacctatgtc
     4021 cgcacattag ctgtagatac aggcaagaaa cttggttacc ctgcgcacat gtctgatctg
     4081 acccgaacag caagtgccgg tatgtcccag aaggatgctc tgacattaga agaagtagct
     4141 caagctgtga aaaatgggac aatcgatgat tgtttgctgc caatagaaaa aggagtggaa
     4201 cggttcaaac gagtagatat tactgatgaa gtatggcaga aagtaaaaaa cggtatgaga
     4261 cttgattata ctgtatttgc gctcccagaa atgccgtcag aagaaattgc tttgttttat
     4321 aaaggaaaag ttgtcagtat ttatcagcca aacccgaaag aaaaaaacaa attaaaacct
     4381 agtaaagtat tgagaaatga ggaataacga atgaatatca tcaagatcag acatccttac
     4441 caatcagaac aaattccaga agacgatgtc gttttagtgc tgggattttt cgacggcgtg
     4501 catatcggac accagaaagt cataaagaca ggtatggaaa ttgcacaaaa agaaggattg
     4561 aaattagcat tgatgacttt caatcagcat ccatctattg tctttaaaaa gatcgatcct
     4621 agcagcgtga aatatttgac tagccttaag caaaaagaag aaaaaatggc cgctttgggt
     4681 atagattatt tatatgaagt tgattttact tcttcttttg ctcatttagc accgcaggaa
     4741 tttgttgatc aatacatcgt agggttacat gcaaaatatg ctgtttccgg ttttgattat
     4801 acgtatggac caaaagacat tgcagatgtc gctcattttc ctgaatatgc caaaggaaga
     4861 ttcaaaatcg tcacagtttc taaagaagaa gaacaaggtg aaaaaatcag ctctacccgt
     4921 attcgtggat tactagacag cggacaagta aaagaagcag caaaactatt aggttgcaca
     4981 tatgaggtag aaggggtagt tgtccatggc gatgcacgag gcagactact aggattccct
     5041 acagcaaatg tcaaagtaaa gagcacggtt catttgccta aagaaggtgt ttatgtgtcg
     5101 gaaataaaaa ttggggaaac atggtatcca gccatgggtt caattggaca taatgataca
     5161 ttcggtgaag gacgggagct gactgtagag ttgtatattt tggactttaa tcaagatatc
     5221 tatggtgaac atgtcgcggt acgctggaat caatttttaa gagatcaagt gaaattttct
     5281 agtgtagagg aattgattga acaactcaag gaggatgaac aagcaacagc tgaatatttt
     5341 tctcagcaat aaaacattat gcataaaatc tcttgtttat gtataactag caattacaat
     5401 aaaatgggtg ataaataagc ccaggaaagg ggctgtgaca aaagtcttgt cacagccttt
     5461 ttttccaaat aaatggtttt tcagaagtag cttcttcgga aataagccga aatttcttga
     5521 agctgaccac ttctgtcaca acctctttct ttatagaaat aaaaggacac tagcaattca
     5581 tgaaaacgat tgctagagcg tatcatttgc tttagactat atatcttggt gtacactcac
     5641 tttaaggcgg aaataaaagt tatccgtaat aacaggttta ggtatgaaaa aggagtgggt
     5701 actatgtaca aggaattaga aaacaaagtc gcagtagtaa ctggtggctc aaaggggatt
     5761 ggaacagcga ttgctcaacg attcgggaaa gaaaaaatga atgtagttgt caactataac
     5821 tcggataaag aaggagcaga aaaagcagtc aaagcaatcg aagaggcagg cggaaaagca
     5881 gtctctgtac aagcagatgt cagttctgaa gaaggaatac agcgtttact tgatacggct
     5941 ttagaaaatt ttgggacact ggacgtttgg gttaataatg ctgggatgga aaatcagcat
     6001 ccaacccatg aacttagcct tgaagattgg gaaagagtgt taaaagtcaa tttgactggc
     6061 gtttttatcg gaacgaaagc ggctttaaat tactttacag agaataataa aaaaggaaat
     6121 atcatcaata tgtcttctgt tcatgaacag atcccatggc caacgtttgc tcattacgct
     6181 gcttcaaaag gcggggtaaa attatttacc gaaacggtag caatggagta tgcaccgaag
     6241 ggaatcagaa tcaatagtat aggccctggt gctatccgta cacctattaa tgcggcaaaa
     6301 tttgatgatc ctgaacaaaa agaactcttg gaaagtatga tcccactagg acgcgtaggt
     6361 gaaccaaaag aaatagcggc gacagctgca tggttggctt cagacgaatc cagttatgtt
     6421 acaggtatta cactatttgc agatggtggg atgactttat atccttcttt ccaaggtgga
     6481 aaaggataag ggtgaataaa aatgggttta ttgattgcat tgatcccggc agttggctgg
     6541 gggatccagc cactgatttt gaaaaagatt ggtggcagac caacaaatga gatattagga
     6601 actggtattg gagcggtgct tgtcggctta ctcgttcaat tattcgcttc tccagctggt
     6661 atttcagtga ctacattttt gattagttta ctttctggtg cattttgggt tattggacaa
     6721 acaggacagt atacatcttt caacttgatt ggtgtttcta aaacgatgcc aatttcgact
     6781 gcattacagt tagtcggaac ctcgttgatt ggtgtcttcg cttttggaga atggtctgga
     6841 agtatgggga aaatcattgg agcagcagca atcattcttc ttgtatttgg ttctgcttta
     6901 acggcaatca gtgatgatcc tggaaaaaaa ggcggtatca caaaaggaat tagtctatta
     6961 gcatcaacaa gtattggtta ttgggtatac agtgcattgc ctaaactagt tgatgcaagc
     7021 ggactttcca ttttctttcc gcaaatgatc ggtgtctttt taggggcagt gatttatgtg
     7081 attttccgta aaccaaccgc attttctgaa gacaagagtt ggaaagcaac gatcgttgga
     7141 gccatcttta gtgtgtcagc attggcttat attttttcag caaatgaaaa tggggttgct
     7201 actgcatata tcattacaca gctaaacgta gttatctcta cattaggcgg tatgtacatc
     7261 ctgcatgaaa ataagacacc aaaagaaaaa aaattaacga ttatcggatt attgctgatc
     7321 gtagtaggaa gcatggtcac ggtctttatt tgaggataaa gatggtaaaa tttcatttat
     7381 taaaaaaata tttgtttgaa ccaaacagta agtacttata aaaaaatagc gctagaattt
     7441 ccaacatctc tggaatttct agcgcttttt aattgtttaa gatacaaggg aaatatctgt
     7501 ctggatcaat aatttttcat tgatccattg actaaagttt acgacataat tgaagttacc
     7561 accgattagt atctccgcat gattgtcttt ataaagatcg tattgtaaaa gacggtcttt
     7621 tttatttgcg taaacatcgt tatggtactg gactaattgt tctcggaatt gattgattgc
     7681 tgtaaaatca cgatattgaa ggttgaaacg catcgtgatt ggtgcattta gcatgaatcg
     7741 ctgcatttct tttgctgctt cctctgcttg atctccgtat aggaactcaa aaagattacg
     7801 ttcagaaaat ttccattgcc cgccaacctt tgttcctttt agttttcctt catgaagata
     7861 atttctgata gaacgtgtag taacacctaa ttgttcggct aattcattta ctgagtaaaa
     7921 atctttcaat gttcaccctc ctatgtgaat ggttctactg acttagttga tatttgctta
     7981 atcacgaaat gtagaaagaa cgattttaat taaggtcatt gtaaaaatca agtcagaaaa
     8041 ttctaacttt tatttctcta aagaaattcg ttctctccta aagtgatatt atatttaaat
     8101 atacctgaaa ataatgggca gtattatgaa agatcactga tattttctcg tattttttcc
     8161 ttattcaaaa gttttgcagg aaaattgctg aaaaaataat tttactaagt agaaaattca
     8221 aagccattca atcagtgatt tttttcagca caagaaagac tccttataaa aatagcagat
     8281 actttgtcaa ttaagtgttt aaccagggat gataaaaagg ataggattga acaaaacctg
     8341 tataaggtga tgaatagttt cctcgccagt aaaaggttta ttcgtataaa gctttatcgc
     8401 caaaatttat catgaccttt tttatcttca atattaaatg aaatcaattg ttcaatcaat
     8461 tcccagttga ttacactttt ccaaggaact ttgatgacgt tatccgtata tacgtagcct
     8521 gcttcttgga tatttttttc aagggcacga atcgctgctt tttccggtgc gatagaaaaa
     8581 tgatttttag caaaactaaa tgcaataata aaggtaccat ggtcagtaaa cataggttgg
     8641 ttccatttta cagttgtgtc tagctgggga tacgtttctg ttatcttagc aaaaaggtct
     8701 ttgatctttt gttgatgttc tttttctttg atttgattga tgatcggctg aaatttttcc
     8761 attctaaaac gcctccatta agtggtttga tttattttac cagaaaaaca atagttatgt
     8821 ataaaaaacg aacaaaacac aagtaatgtt gtaaccgcta tatttatatg ataagatgtc
     8881 tcaaataata aaatagaaaa gagacataaa aatgattgac ttggcaaaga aattcttaca
     8941 cgaaaatata tattttgagt tgtatcatca tcgagccatt tatacaaatg aagatgcttt
     9001 ggtaataaag aaagaacaag gatttacagg tacagagacc aaaagcttat tcttaaaaga
     9061 taaaaaagat aataactacg tatatctgac ttttactacg aaacaaacgg atttcaaagc
     9121 attagggaag atcgtcggta aaaggctttc tattgtttca tcagaacgca tggaagaaca
     9181 aacgggacaa aagcagggcg ctgtttctcc gtttggttat gaaaaacaga ttccgattat
     9241 tattgatgaa gagctcttat caaatgaaaa acttgttttt gcaccaggta gaccagatca
     9301 aacgatggtc atccaaacgg ttgacttaaa caaaatcatc cagctacttg agatgccgat
     9361 atttttgatg ccggcaaacg aaaaaaacaa ttaaccaagt aaaatagtgc atacttggag
     9421 gtgaagcaac atgataagtt atccattatt agaaagaaat gcaacgattg gggttactgc
     9481 accatcctca ggcgtatcag aggaacacca ttcgttactc gaatcagctt taaagagaat
     9541 ggaagaaaaa tctttccaag tagttactgg aaagacgctt tggacgcaag ataaggaaaa
     9601 atcaggtcca gcaagaaaac gagcagatga attcaatcaa atgatgcaag atgaaaatat
     9661 ccaaatgatc tttccgactt ggggaggaga attattgatt gagattctcg attttgtcga
     9721 ttttgatgct ctacaaccaa aatggatagt aggttattca gatattagta cgttgctact
     9781 tgctgtcaca ttaaaaacag ggatagccac tgcacatgga actaacctta ttgatttaag
     9841 aggagagtac ttggatgaaa cgacagcaat gtgggaaagt gtactgaaaa caagagaagg
     9901 agaatcgatt ctacagcaat cttctgaaaa gtatcaaaaa gtgtggcccc atgagcattc
     9961 atcatcttct gttttccatc tcactgaacc aacaaattgg caatcagtca gcggagatgc
    10021 agtaaggatg aagggacgat tattaggtgg ttgtattgat acgatcaggc atttaatcgg
    10081 tactccttat ggagatgtcc aatcttttaa aagaaagtat aatgatggaa agccgatctt
    10141 gtggtttcta gaaaactgtg agctatcgtc agttgattta agaagatcac ttgttcagat
    10201 gaaactggca ggctggtttg atggcagctc ggggatcatg ttcggtagaa gtgcggcaga
    10261 ggatttgtta gattataaaa tgaaggatgt atacgaagat ctgtcaaagg aattaaaact
    10321 accgatcttg tatgatattg attgtggtca tgtaccgcca caactgacat tgattaatgg
    10381 tgcctatgca gaagtagcgg tagaagatag aaaagcgact gttttgcaaa cgtttattta
    10441 aaaaattttt tcctgccttg gagtctatca aagaccaata aatctaaata gaaaagaaag
    10501 tgaaagaagc tgacaaaatg ctgtcagctt ctttttgtat aacatattag aaagtctaat
    10561 tatctataac tgtcacatcg attaactgtt tcacgtcatt gggatttcct gtaggaatag
    10621 ctactacaga tgcattatca atgatttctt gagttgtttc tctaatgaac gctggataag
    10681 atgtttgatc tgcaggcatt tgccaatgtg aaggaactgg ataactagtg attgtcccgt
    10741 catggttact tgaatacact aaaactccct ggtaactgta tttcccagtg agcataacca
    10801 catctttcgg atagactgca ctccctgcat cataaggggc gataggtgtt cctgcaggat
    10861 aatgaataac atgtaattcg aaatcacccg atgtatctct aaaagtatta cctctaatag
    10921 ctagccaaac acgtgcgtac tcaatttgta gatcagaata tcctgctaac ggatctattg
    10981 actgagaaga ctgtgaggag gttgtgtcta ttgttgaaga agaaatattt gtctcaactg
    11041 tactactaga tgtagaagaa gtattgggct ctgagacttt actgcttgtt gaagatgtat
    11101 tcgtttcagt agaagctgat ttctgagtac ttgatttttc agctgaactg gtttgtctga
    11161 ttgaactttt gtctgtggtc gcagatggat cactattttc tttactagga gacgtacatc
    11221 ctacaaggaa taaagagacc aacaataaaa taaaacctaa ctttttcata taaaatacct
    11281 cattattttt ttaataccag tatagcataa tcctgaattt ttgaatccgt aaaaccttgt
    11341 ctatgaatat aaatagagtg tatcttcttt gataaatgtc agaaaaagtg tgacaaataa
    11401 tcatcagtaa aattacttgt cacactattg ataaggagta tttaattgaa gagaatgatt
    11461 aggagaaagg atctccgtac tttttatagt aatcatagaa tccaagtttg tatagacgaa
    11521 tcgttttttc tcttatttct tctgtttcaa aatggactgc ttgaagaatc aagtctgtga
    11581 attctatagg agctgttcca ttcgcagtaa tcaaattacg atctttcaca gcttgttgtt
    11641 ctataaaatc ttctttattc tgataatttt ccgattctaa ccaaggaaat tgcgcatttc
    11701 cggtgtgttt gtaaccttgc aataatccgc tctgagctaa ataatcaact gccccacaaa
    11761 tagcagctac tggtacgtct gtttttaaca atttatcgat tatttgatat aaatgatgat
    11821 tttttatgtc ccatgaattg ccaccgatca taataaaaag gtcaactttt tcaggtattt
    11881 gttcgattaa gtaatcgatt tttgttttta atcctccaat ggaagtgacc tctgattgga
    11941 tagaagcagt tttgttttgc catttctcat tttggtttag tgtgctagta atataagcac
    12001 cttcccaatc ggcatattcc tctaatagaa acgtaatcgc agttttcatt ttcaagctct
    12061 cctttactat ctataacaag gacaacagtt ttaacctaca gacattcatt aaaattgggt
    12121 agcgacagcg aaaacaacaa ttcttaagtt ttagacagag tatacagata gtcaacttaa
    12181 ttaaatacga actaaataaa aatgacaggt aatcattttt gtttaccagc attataacat
    12241 tttgcataca tggatgacaa aagaaccaat tcccacttgc ttgagtacaa tattaaaaga
    12301 aactggaagg caaaaagtaa ttatagaaac gaaaaataaa tcatatcggg cactcagaca
    12361 tgaaaacaac cctagagata tataactagg taaccagttt aatgaaagaa aaaatcatcc
    12421 aagaagtcga ttcttggatt ttttagtgga tttgttcgcc aaatacgttt agtatgcgta
    12481 tatgagaggt tgtaagcaaa gcgttgtggt ctgagcactt aaggaggaat ctgtgaaaat
    12541 agcttttcat atttttgcag attttgactt aatgccgaag gtcagctttg cgattaccgt
    12601 ttatcgagag gctgtaaaag caccgtgtag ctccgatgac aataagcaag catttttaga
    12661 gctaggtttc cttgattcta aatatgcggc ttatttcaat gagttggtgc ttgaacgcga
    12721 ttttaagaag gtcgaaaaca ggcacgactt ttcgacgtaa ggagaaagaa tttcaatgat
    12781 agaaacaata aatcccgcag aaaacaaggt ttctgcgtac attcatatcc cattttgcga
    12841 gcatatctgc tattactgtg attttaataa agttttttta gaagggcagc cagtagatga
    12901 gtatgtggaa atgctgctga atgaaatgaa aataatgcta gaaagtcatc cgacagcgaa
    12961 tttagaaaca ctttacgtag ggggcgggac accaacttct ttatctgcta aacaacttga
    13021 tcgactgtta tcaggtgcta gagagatcct gccttttcaa aatggtaatg agtttactgt
    13081 agaagcgaat ccaggtgatt tgacccgtga aaaacttcaa gtaatgaaaa actatggcgt
    13141 caatcgttta tccatgggag tgcagacatt tgataatcgc ttattgaaaa aaattggacg
    13201 taaacacacc gcagaagatg tgtatcaaac tatgcaattt ttagaagcag aaaattttac
    13261 caatgtaagc atcgatttga tttatgcatt accgggacaa acactagaag gatatctgga
    13321 tactttggaa aaagctttgg ctttggatct gcctcactat tctttgtact cattgatcct
    13381 cgaaaacaaa acaatgttca tgaactgggt acgacaagga agactcgaac tgcctgatca
    13441 ggaaacggaa accagaatgt ttgaagagac gattgaagca atggaaaagc atggacgtca
    13501 ccaatatgaa ataagtaact ttgggctctc cggacatgaa tctcaacata acctcatgta
    13561 ctggaacaat gaccactatt ttgggtttgg agctggtgct agcggttatc ttggagatat
    13621 tcgttaccgc aacaaaggac caatccaaca ctatttacgc ccattacgag caaatgaacg
    13681 cccggtattg gaagaagaaa aattgacacg aaaaaatcaa atagaagaag aaatgttctt
    13741 aggactaaga aaaaaaacag ggattactaa aaaacatttc tatgatcgct atcaaaaaac
    13801 aattgaatcg gtgtacggtg atgtgctaag ggaattagag caagaagggt tacttgttaa
    13861 tgaagaagac cgtgtttatt tgacaccaag agggaccttt ttggggaaca atgtgtttga
    13921 gcgctttttg tttgaaaaat agtttaaaga atatttgttt tttatctgaa tttaaataaa
    13981 aaaagttcaa aaatacaata aaggactatt gaaacgttga tataactgga tttacatcaa
    14041 ttatttagaa ttagcactct tgtgtttaga gtgctaaaaa atggagtctt tctcttgaca
    14101 ggagaagggc ttcttgctat atttataagt ggattagcac ttagaatata tgagtgctaa
    14161 tgagaggtga ggaagatgtt aacaaagcga caaaacgaca ttttacgtct gatcatccaa
    14221 cactatacga gtagtggcgt gcccgttggt tccaaaacat tgatgtctga gggagtcaag
    14281 gccagctcag caacgattcg caatgatatg aaagcattag aagatgaagg attgctgttg
    14341 aagactcact cttcttctgg gcggattcca tctgctttag gctatcgtta ttacgtggat
    14401 catttgttaa aacctgctcg cgtagcagaa gatgatttgc tgctgattcg tcagtctcta
    14461 ggcagagaat ttcatgaaat caatgagatt attaagcaat ctgctgagat attatctgag
    14521 ctgacaagct atacgacttt ttcattggga cctgaaataa aagaccgccg actgactggc
    14581 tttcgtatcg tacccttgaa taatcgacag attattgcta tcgtcgtaac agatatgggg
    14641 aatgtagaaa gccaagtgtt cactcttccc gaatatatgg gaagtcagga actagaaaaa
    14701 atggtacaga ttgtaaacga ccgtctagtc ggagatcctc tgatgacggt gtaccataaa
    14761 cttcgtacgg agattccgat gattcttcat aaatatttcc aaacgacaga agggatgtct
    14821 cagttatttg acaccgttct tggtcatgtt tttgaagata aggtttatgt cagtggacaa
    14881 atgaatctct tggattatga gccccgtcaa gatcttgatc agttcaaatc gatgttttct
    14941 tttatgaaag actcagacgg acttacacaa atgatcactc cgatggatag caatattcat
    15001 atcaagattg gtgctgaatt aggcaatgat ttattgcaga atatgagtat gattcaagca
    15061 agttacgaga tagatggtca tggaagaggt acaatagcct tgttagggcc tactagtatg
    15121 ccttattctc ggatgttcgg tctagtcgat gtttatcgaa gagaactagc agctaaactt
    15181 gctgattact accgttcgct tgacttgtca aactcgtaat gtgaataacg aagctatttg
    15241 cagctgatcg ttctctcttt cttagtaaga gcaatcaaac agctgactga ataatgaaag
    15301 gaagactgta tcgtgaaaga aaatcaagaa gaactagata aagaaatgac agatgctcag
    15361 ccagaaccgg aaatcgatgt cgaagctgca gaagattcgg gtatttcaga agctgaagcg
    15421 gaagaattcg aaacagcgaa attaaaagct gagttagaag aaatggaaga taaatacttg
    15481 cgggctcgtg ctgaaatcgc aaatatggca aatcgaggaa aaaatgagcg tgagcaatta
    15541 caaaaatacc gttcacaaga tttagccaaa aaattacttc catcaattga caacctggaa
    15601 cgtgcattag ccacagaagt gtcagatgat caaggggcag gtttgaaaaa aggcgtggaa
    15661 atggtcttgg aaagtttgcg taacgcactg gaagaagaag gaattgaaaa aatccctgct
    15721 aaaggagaag cctttgatcc taatcttcat caagcagtac aaactgttcc agcgactgaa
    15781 gatacaccag ccgatacgat tgtagaagta ctacaagaag gctacaaatt acatgatcgc
    15841 gtgttaagac caaccatggt cattgttgca caataattgt gcggatataa aacttacact
    15901 ttcaattaaa gaaggagacg ttaattatga gtaaaattat cggtattgac ttaggtacga
    15961 ctaactctgc agtagcagta ttggaaggaa acgaagcaaa aatcatcgct aacccagaag
    16021 gaaaccgtac aacaccttct gttgtatcat tcaaaaatgg agaaatccaa gtaggggaag
    16081 ttgcaaaacg tcaagctgtg acaaacccaa atacgatttc atcaatcaaa cgccatatcg
    16141 gtgaagcagg ttacaaagta gatgtagaag gtaaatcata tacaccacaa gaaatctcag
    16201 caatgatcct tcaatatatc aaaggattcg cagaagacta tttaggtgaa aaagtcgaaa
    16261 aagcagttat cactgtgcca gcttacttta atgatgcaca acgtcaagca acaaaagatg
    16321 ctggtaagat cgctggtcta gaagtagaac gtatcgtcaa tgaaccaact gcagctgctc
    16381 ttgcctatgg tttagataaa acagatcgcg acgaaaaaat cttagtattc gaccttggtg
    16441 gcggtacttt tgacgtatct atccttgaac taggagacgg tgtctttgat gtattgtcaa
    16501 cagctggcga caaccatcta ggtggggacg actttgataa caaaatcatc gactacatgg
    16561 tagcagaatt caaaaaagaa aacagcattg acttgtctca agacaaaatg gctttacaac
    16621 gcttgaaaga cgctgctgaa aaagcgaaaa aagatttatc tggcgtatca agcacacaaa
    16681 tcagcttgcc atttatcaca gcaggagaat ctggaccatt gcatttggaa atgacattga
    16741 cacgtgcaaa atttgatgaa ttaacagctg acttagtaga acgtacaaaa gtaccagtac
    16801 gtcaagcgct aaaagatgca ggtttatcac aatcagaaat cgacgaagtt attttagtcg
    16861 gtggatctac tcgtatccct gcagttgtag aagcagtacg taaagaaaca ggaaaagaac
    16921 caaacaaatc agttaaccct gatgaagtag ttgctatggg tgctgctatc caaggtggcg
    16981 tgatcactgg tgatgtgaaa gatgttgttt tacttgacgt tacaccattg tcattaggta
    17041 tcgaaacaat gggtggagtg ttcactaaat tgattgaccg caatacaacg attccaacaa
    17101 gtaaatcaca agtattctca actgcggcag ataatcaacc agcagtagac atccatgtat
    17161 tacaaggtga acgcccaatg gctgctgaca acaaaactct aggaagattc caattgacag
    17221 atattccagc agctcctcgt ggtattccac aaatcgaagt aacattcgat attgataaaa
    17281 acgggattgt aaatgtatct gcgaaagatc taggtacaca aaaagaacaa aaaatcacga
    17341 tcaaatcttc ttcaggtcta acagacgaag aaatcgaacg tatggtaaaa gatgcagaag
    17401 caaatgcaga agcagataaa gctcgtaaag aggaagttga cctacgtaat gatgtagatg
    17461 cattgctatt ctctgtggac aaaacattga aagaattaga aggcaaagtg gacgaagaag
    17521 aagtgaaaaa agcagaaaca gctcgcgatg aattgaaagc cgctgttgaa gcaaacaaca
    17581 tcgaagaaat gaaaactaaa cgcgatgcat tgaacgaaat cgttcaaaac ttgactgtta
    17641 aactatacga acaagcggca caacaacaag ctcaagaaaa cccagaagca gctcaaggcg
    17701 gagcagatga tgtcgttgat gctgattttg aagaagtcga tggcgacgat aaataatcag
    17761 ttcactgaat ttcgagagaa ggccaaagtt gctactttgg ctttttcttt tgaaaaatag
    17821 tttgaagtat cggtttttgt ttcaaacaaa atatgatatg ataacaagcg acgtgaaaat
    17881 gatgagaacc aataggagga aagcctatgg caacaaaacg tgattattat gaagtcttag
    17941 ggctctcaaa aggagcatca gaagatgaaa taaagaaagc ttatcgtaag ctttcgaaaa
    18001 aataccatcc tgacatcaat aaagaacctg atgcggaaga aaaattcaaa gaagtatcag
    18061 aagcatatga gattttaagt gacccgcaaa aacgcgctgc atatgaccaa tacgggcatg
    18121 caggcacaga tccaaattac ggtgctggtg gagctggtgg cggatttggt ggattcggcg
    18181 gcttctctgg tggcggcttc ggtggttttg aagatatctt cgactctttc tttggaggag
    18241 gcggtcggtc agtcgatcca aatgcgcctc gtcaaggtgc tgatttgcaa tatacggtcg
    18301 acttgtcttt tgaagaagcg atttttggtg tagaaaaaga aatcaagtat aatcgggaag
    18361 aaatctgtca tacttgtggt gggaacggtg caaaaccagg cacacaacca actacttgtc
    18421 ataaatgtca tggtgcaggt acgattaatg tagaacgcca aacaccactt ggacgagtga
    18481 tgagccgtca aacttgtgat gtttgtcatg ggacagggaa agaaatcaaa gaaccttgtc
    18541 caacctgtca tggctcagga catgagaaga aagcacattc agttaaagtg aatgtaccag
    18601 ctggtgtaga agaaggacaa caaatgcgtt tagctggtca aggagaagct ggagaaaacg
    18661 gcggaccatt tggtgatttg tatgtggtct tccgtgtaga agaaagtgat atctttgatc
    18721 gtgaaggttc tgaaatttac tatgaattgc ctttaagttt tgtacaagca gctttggggg
    18781 atgaagtcca agtaccaact gtccatggag atgtgaaatt gaagatccct gctggaacac
    18841 agacaggtac gaacttccgt ttacgtggaa aaggcgctcc gaagttacgt ggtggtgcaa
    18901 caggcgacca acatgtcaaa gtaaaactga tcacaccgaa aaatctaaat gaacaacaaa
    18961 gagaagcatt acgtgcattc gctgaagctg gcggcatcaa agttgaagaa cagcaagaag
    19021 acggtttctt cgataagttt aaagatgctt ttggcgggaa aaagcggaag tagtttttct
    19081 agtaaaaacg ctaagtcatt aataattaaa aaccagacga acaatcatat gttcgcctgg
    19141 tttttttgta gttgtcatgt ttgtaccaac aaaaaagcca gctttagaat atgataatcg
    19201 tcatagtttc taggggtata accagtgaga gaatggaact tgttcaatcg atattgcaag
    19261 gtgtttttat gaataaataa ttcttctgag caatttttga tgcttccgtt atttttactg
    19321 aagcatgcca aagtcttctt gaacaaatgt acttcttctt ctgtcaggct tttcaaaata
    19381 cgttttacat ataatgttcg ttgatctgac gggattgctg gtaaaacgat cccgaggtct
    19441 aaatcttcaa aaaagcggat ctcgttcaca gattgatgga aagctatcca ttcgcaaact
    19501 tgtttggcat gaaggaaaga ttgcggtgtc tcttgctctg tataacaaag cgacccaatt
    19561 ccaaagttta gctgtaactg atacatttta ttaaactttg tctggatttt atcaagcaat
    19621 gatagcaatg aggctctgga aatccgattg actaggataa tgatttgttg tctatgtaca
    19681 gtgagcaaag cctgtccgta ataagagaag accctttcga gcaactccaa taaaggattg
    19741 atccgttctt gacacaattg ctgattgtca gaaagttgtc ccacaactac ataatatgga
    19801 gaagaaaaat caagctcaat taagtgaggg tggtatcgac tatgtacttg atatcatcaa
    19861 tgaaccgatg gtactttctt atgcgatgga acaggtagag cgattgcttg tttgtgcagg
    19921 aaaacaagcg atgcggctga tacgattagg tgagaaaata agaagataaa aatacacggt
    19981 cccttcatgg cgaccgtgca tttttggttt ttattaaata tttaatactt tattcaagaa
    20041 atcttttgtc cgttcatttt gcggattttc aaagatttgt tgaggcgttc catcttctaa
    20101 aaagtttccg tcgtcaatga acatgacgcg attggccact tctttagcga accccatttc
    20161 gtgcgtaacg ataaccatcg tcataccttg ttctgctaac tttttcatga cgttcaagac
    20221 atcaccgacc atttcaggat cgagtgcaga agtaggctca tcaaaaagca tgatgtcagg
    20281 gttcatcgct agagcacgag caatagccac acgctgtttt tgtccaccag aaagcatttc
    20341 aggatacata tcttttttat cttctagacc aactgtctgc agtaatttga ttgctttttt
    20401 ctctgcttct tctctagatt ctttcttcag gtccatcggt gctaaaatga tgttttccaa
    20461 aatagaaaga tgagggaata ggttaaagtg ttggaatacc attccgatat gttgtctcac
    20521 caagttgata tctgtgcttt tatccatcaa gtgggcgccg tcaataataa tttcaccgtc
    20581 agaaggttct tctaaacgat tcaagcaacg caagaatgta ctttttcctg aacctgaagg
    20641 gccaatgata cagacgacat ctccttcgtt gatggataca ttgatgtcgt ttaatactgt
    20701 gttatcgccg tattttttga ctaaatgctc aactaagatt ttttctgcca tcttacttca
    20761 ccttcttttc taaaactttt gctaattttg tcaatgctgt gatcaaaatc aagtacatga
    20821 tcgcaatgat caagtaaaca tacgtacttt gtgttgtacg tgcaacaatg atcttaccag
    20881 tttgcagcaa ttcgactaca ccgattgcgg aaatgatcgt tgtgtctttt aatgagataa
    20941 cgaactgatt gacgaatgat gggatcatga tgcgtatcgc ttgcggcaaa atgatttttt
    21001 gcattgtccg attataagaa agacctaaac ttctggaagc ttccatttgt ccgacaggaa
    21061 cggcgttgat cccgcctcga acaatctctg cgatataagc acttgcgtta agagtcaagg
    21121 tgataacacc agcaaggaag tcaggaatcg taaatccaac gataccaggc aacccaaaga
    21181 aaataaagaa cgcaagaacc atcattggaa ttcctcggat gatatcgaca taaatactag
    21241 caattgtgcg aagagcgcgt attggtgcta cactgaataa tccaaaaatc acaccgatta
    21301 ctatagccaa agcaaaggag atcaaagtta ggagaattgt tctccaaagt cctttcaaca
    21361 atgcttgata gttgttttgg ataagtccaa gaaatgttga ttcatcagca gtggaagact
    21421 cactggaagt ttctgaacca tccgctacat attctttaat aatcttatcg tattcgcctg
    21481 ttctttttaa ttctttcaat ccttcattga acatattaag aagctcagga ttttgtcctt
    21541 ttttaacggc aaatgcatat tttccgccag attctttttt gatcggtgtt tccaattctt
    21601 gtccttgttt gatcgcataa ccgattaccg gataatcatc catcattgca tcgattgcgc
    21661 caacttttaa cccgtcgtac aattgatcag cagcatcaaa atatttgata gaatagccat
    21721 attcagattc atggtcgctt aaaaattcag cactttcggt accaactttt gctccgactg
    21781 tttttccttt caaatcttca taagacttga tcgaagtatc tccttttttg acagctaatt
    21841 ggatcccgct atcaaagtaa gaatcagaaa aatcatagct tttctttcgt tcatctgtta
    21901 cagtcattcc ggcaatcatt ccgtctgctt gtcctgattc caaagcttgc aaagcagcag
    21961 agaaaccacg gtagtccatt cggatgttaa atccttgcag tttggcgatg ttttccatca
    22021 attttacatc gatgccttcg tactcgccct ttgcgttttg aaattcaaat ggagcaaaag
    22081 cagagtcact ggcaattacg tatacgtctt ttttgggctc tattttttgc attgtctcgc
    22141 ttgtgcttga ctctgccgtt gtagtgttgt cagcttgtgc aacatgacca aacgcaagtg
    22201 tcacaagtcc tgtcattaag aaaacaaatg agtgaaataa atgctttctt ttcataatca
    22261 acctcctaaa tttccaatat tttattatta taggcgaaaa gtgctgaatc agacaagact
    22321 gtaagctcga aaaaatgaaa aaaatgcgag tttctaacat tttatgttat aaaacataac
    22381 atgtataata agataaaaaa gtggcgaaag tatgttcggt gtggtataat tttttagtaa
    22441 ggaatgcctt tgctttcctt ttctttttat tggtcgtaaa atgaaaagga atgaatgaaa
    22501 aggaggacga agaatgattg agagagatac ctcccgacac tttgagcttg tctcgaaata
    22561 ccaaccggct ggtgatcagc ctgaagcgat taaccaatta gtggatggcg tagtcggcgg
    22621 gaaaaaagca caaatcttat taggtgcgac tggaacaggg aaaacatata cgatttccaa
    22681 tcttattgag aaagtgaata aaccaacact gattattgcc cataacaaaa cattggctgg
    22741 tcagctgtac ggggaattca aggaattttt ccctaacaat gctgttgaat attttgtttc
    22801 ttattatgat tattatcagc ctgaagctta tgtgccttca agcgatacgt atatcgaaaa
    22861 agattcaagt gtaaatgatg agatcgacaa attacgacat tcggctacta gttcattatt
    22921 agaaagaaat gatgtgatcg tcattgcatc cgtttcatgt atttttggat taggctcgcc
    22981 ttttgagtac caaaaacaag tagtttcgat tcgacaggga gcagaactag atcgcaatca
    23041 gttgattcgt gacttagtca gtatccaatt cgaaagaaat gatatagatt ttcagcgcgg
    23101 tcgttttcga gtgcgcggtg atgtcgtgga gatttttccg gcttcaagag atgaacgtgc
    23161 cttacgtgtg gagttttttg gagatgaggt cgaacgtatc cgagaagtca atgcactgac
    23221 aggtgaagtt ttaggagaaa cggaacacgt agcaatcttc ccggcgactc actttgtgac
    23281 gaatgatgaa catatggagc atgccgtagc gaatatcaaa gaggaattag aacagcgttt
    23341 aactgtcttg cgaaatgaaa acaaacttct ggaagctcaa cgtttagaac agcgaaccaa
    23401 ttacgatatt gaaatgatgt tagaaatggg ctacacgtcg ggaattgaaa attattctcg
    23461 gcatatggac ggacgtaaag aaggtgaacc gccttatacg ctattggatt tctttcctga
    23521 agattttttg atcgtggcgg acgaatcgca cgtaaccatg cctcaaatca gaggaatgta
    23581 taatggtgac cgagcgagaa aacagatgct agtagattac ggtttccgtt tgccatctgc
    23641 tttagacaat cggccacttc ggttagaaga gtttgaaaaa catgtcaatc agatcattta
    23701 tgtctctgcg acgccaggac catatgaaca tgaacaaaca gataccgtta tccaacaaat
    23761 catccgtccg acagggctgc ttgacccagt gatcgaagtt cgtccaatca tgggacaaat
    23821 cgatgatcta gtaggcgaaa taaatgaacg agtcgaaaaa gaccagcggg tgtttgtaac
    23881 gacattgacg aaaaaaatgg cagaagacct cacagattat ttcaaagaat tagggatcaa
    23941 agtcaaatat ttgcatagtg atatcaaaac gctggaacga acagaaatca ttcgagatct
    24001 tcgattaggt gaatttgatg tgttagttgg aatcaatttg cttcgtgaag gattagacgt
    24061 acctgaagtt tcccttgttg ctatcttgga tgcggataaa gaaggctttt tacgtagtga
    24121 acgttcctta gtccaaacga ttggacgagc tgctcggaat gaagaaggta aagtaatcat
    24181 gtacgcagac aaagtaacag attctatgcg tctagcgatg gatgaaacgt caagacgtcg
    24241 tacgattcag cagaagtaca atgaagaaca tgggatcgtt ccaaaaacga tcattaaaga
    24301 aatccgagat ttgatttcta ttacgaaaga atcggaagat gatacaaaag aagcggtaca
    24361 agtctcgtac gaagaaatga cgaaggaaga aaaagacacg ttattgatga aattagaaaa
    24421 agaaatgaaa gatgcggcaa aagctttgga ttttgaaaca gccgcgaatg tgcgagatat
    24481 gattttagaa ttaaaagctt caaagtagga ggacaacatg gctaacgata aaattacgat
    24541 tcatggtgca cgtgcccata acttgaaaaa tatagatgta acgattccac gagataaatt
    24601 cgtggtcgtt acaggtttgt ccggttctgg aaaaagttcc ctagcatttg atacgctgta
    24661 cgctgaaggg cagcggagat acgtagagag cctttctgct tatgctcgtc agtttttagg
    24721 acaaatggat aagccggacg tagatagcat cgacggattg agtccggcga tttctattga
    24781 tcagaaaaca acaagtaaaa atcctcggtc gacagtaggt actgtgacgg aaatcaatga
    24841 ctatttacgc ttgttgtttg cacgtgtagg acatccgatt tgtcccaacg atcatatcga
    24901 gattaccagt caatcagtag atcaaatggc agatcaagta atggctttgc ctgagcgcac
    24961 aaagatccaa gtgttggcac cgatcgtggt aaagaaaaaa ggacaacata aaaaaatatt
    25021 cgaacgaatc caaaaagagg gatacgtccg cgttcgagtc gatggtgaga tctatgattt
    25081 aagtgaagtg cctgagctgg agaaaaacaa aaaacatgat atcgcgatcg tcatcgaccg
    25141 gatcattgtg aaagaaggga ttcgttctcg cctatttgat tctttagagg cggccctgcg
    25201 attagcagac ggctatgctc tggttgacgt gatcggtgaa gaagaaatgt tgtttagcga
    25261 acactatgcc tgtccttatt gcggatttac tgttggcgaa ctagaaccaa gactgttctc
    25321 attcaatgcg ccttttggag cttgtccaga ctgtgatggt ttaggtgtca aattagaagt
    25381 cgatcaagat ttagtgattc cagatagaac gaagacactt agtcaaggtg ctatcgttcc
    25441 atggaatcca atcagctctc agtattatcc tcaaatgtta gcgcaggctt gtgaaagttt
    25501 cggtatcgat ttagatacac cattcgaaga attaccggaa gagcatcagg agatcatctt
    25561 gaatgggaca gatgatcttt tccatttcca ttatgaaaat gattttggtg gcgttcgcga
    25621 tgtagaaacg actttcgaag gggtattgaa gaatatcgag cgtcgttatc atgatacgaa
    25681 cagtgatttc acgcgtgagc aaatgcgtct ttatatgaca gaattaactt gtcagacatg
    25741 taaaggttat cgattgaatc cccaagctct atctgttcaa atcaatggaa cgaatatcgg
    25801 gcaaacaaat gagttgtcta ttcaaaaagc agtagatttc ttctcaaact taacgttatc
    25861 tgaacaagag aaagtaattg ccaaaccgat tttaaaagaa gtaaatgaca gactttcatt
    25921 cttggaaaat gtgggactag actatctaac tttgagtcgc gcttccggaa cattatctgg
    25981 gggagaagcg cagcgaatca gattggctac acaaattgga tcgaatcttt ctggagtttt
    26041 gtatatttta gatgaaccat cgatcggatt gcatcaacgc gacaacgatc gactgattgg
    26101 ctcattaaag aaaatgcgtg atcttggcaa caccctcgtt gtagtcgaac atgatgaaga
    26161 tacgatgtgg gcagcagatt atttgattga cgtcggacct ggggccggag aacaaggcgg
    26221 acaaatcgtg gctgcaggca ctcctgaaga agtagctaat gatgaaaatt ctttgacagg
    26281 gaaatatctt tcagggaaaa aatcaatccc tgtaccaaaa gaacgccgta aaggtaatgg
    26341 gaaagcaatc aagatcactg gtgcttcaga aaacaatctg aaaaatatta gtgttgaatt
    26401 tccattagga gaatttgtag cagtcacagg tgtgtctggt tctggaaaga gtacattggt
    26461 caatagtatc ttaaagaaat cgttagcgca aaaattaaat aagaattctg ctaagccagg
    26521 taaattcaag acaatttccg gctacgaaag tatcgaaaag atcatcgata tcgatcaaag
    26581 cccaatcggc cggacgccga gaagtaatcc agcgacttat acaagtgtat ttgatgatat
    26641 ccgtgggtta tttgctcaaa cgaacgaggc aaaaatgcgg ggttataaga aagggcgttt
    26701 tagtttcaac gtaaaaggcg gtcgttgtga agcttgtcgc ggggatggaa ttattaagat
    26761 cgaaatgcac tttttgcctg atgtctatgt tccttgtgaa gtatgtcatg gtaaacgata
    26821 taattctgaa acattagaag tgcattacaa aggaaaaagc attgctgata ttttggaaat
    26881 gacagtagag gatgctgtag aattcttcaa gcacattcca aagattcatc gcaaactgca
    26941 aacgattgtt gatgttggct taggttatgt gacgatgggg caaccagcaa cgacattgtc
    27001 cggtggtgag gcacaacgga tgaaacttgc cagtgaattg cacaaaatct ctaatggaaa
    27061 gaatttctat atactagatg aaccaacgac aggacttcat agcgatgaca tcgcccgctt
    27121 gttgcatgta ttacaaagat tagtagatgc tggtaacaca gttttagtga ttgaacacaa
    27181 tctagatgta atcaaaacag cagattatat cattgattta ggaccagaag gtggagaagg
    27241 tggaggaacg atccttgcga ctggaacacc agaagaaatc attaacgtaa aagaaagtta
    27301 tacaggtcac tatttgaaaa aaataatggt ataaagagga tagatagctg agatagttaa
    27361 aaaaacataa aaaaatgaat ttttgcttgt tttattaata tcagtgttct agaatcatta
    27421 catggtagtt ctttctacac tgattggtat agataaaaac ttcctataag ttcaatccgt
    27481 tcaaaaaaga attgagcaat cggaggactt tcctttgatt gcttttttct ttatggtatg
    27541 atattccttg tgtagttgga aaagaaaaac aagagattat gagtaagtga gagataatga
    27601 tgaacagtat tgaaaatgaa gaatttatcc ctatattatt aggaagcgac atgaacgttt
    27661 atggtatggc acgttctttt aatgaagcat acggcaaaat ctgccaagca tatgcttcgg
    27721 atcagttagc ccctacccgc tacagtaaaa ttgtcaatgt agaagttatt ccaggatttg
    27781 ataaagaccc tgtatttatc gagacgatgc ttcgtttggc aaaagaaaga tattctgata
    27841 agagtaaaaa atatcttttg attgcttgtg gtgatggata tgcagaattg atctcccaac
    27901 ataaacaaga gctgtcagaa tattttatct gtccatatat tgattattct ttatttgaaa
    27961 ggctgatcaa taaagtaagc ttttatgaag tttgtgaaga atatgatctt ccgtatccta
    28021 aaacattgat cgtcagagaa gaaatgttag taaatggaca tttggaacag gaattgcctt
    28081 ttgaattccc agttgctttg aaacctgcaa acagtgtgga gtatctttct gtccaatttg
    28141 aaggaagaaa aaaagctttt attttagaga ctagagaaga gttcgattta attttaggcc
    28201 ggatatacga agccggttat aaaagtgaaa tgattgtaca agattttatc ccgggtgatg
    28261 atagtaatat gcgtgtgcta aatgcgtatg tagatgaaga tcatcaagtt cggatgatgt
    28321 gccttggtca tccactatta gaagatccta caccagcatc gattggtaat tacgttgtga
    28381 tcatgccaga ttataacgaa aaaatctatc aaaccattaa ggcatttttg gaaaaaatcg
    28441 aatatacagg ctttgccaat ttcgatatga agtatgatcc tagagatgga gaatataaat
    28501 tatttgaaat caatttgaga caaggtcgta gcagtttctt tgtgacattg aacggcttga
    28561 atctggctcg ttttgtcaca gaagatcgag tgttcaacaa accctttgtt gaaacgacct
    28621 atggaacgaa tcaatcagat aaagcaagat tatggatggg tgtgcccaaa aaaatctttt
    28681 tagaatatgc tcgggaaaat gaagacaaaa aactagctga gcaaatgatc aaagaaaatc
    28741 gttacggtac tactgtattt tatgaaaaag accgatcaat caagcgctgg ttgttgatga
    28801 aatatatgtt ccataactat attccaagat tcaaaaagta ttttcatgtg aaagaaggct
    28861 agttcatgga gaattttttc agtattttag gcggaatggg cacgatggcg acagaaagtt
    28921 ttgttcgctt gatcaaccac cgaacgaaag ctacaaaaga tcaagaatat ttgaattatg
    28981 tcttattcaa tcatgcaaca gttcctgatc gtacagctta tattttagat cgatcagaag
    29041 aaaatccaat gccgtttctg ctggatgata ttgagaaaca aaatttattg cgaccaaact
    29101 tcattgtgtt gacttgtaac accgcacact acttttttga agagttacaa gcggcaacgg
    29161 atattcctat cttgcatatg ccaagagaag cagcaaatga acttgtccgt cagcatacga
    29221 cagggagagt agcgattcta ggaacagaag gaagtatgaa agctggaatc tatgaacgcg
    29281 aagtcaaaaa tcttggtttc gaaacagtga ttcctgatac tgcgcttcaa gaaaaaatca
    29341 attacctgat ctatcatgag atcaaggaat cggattattt gaatcaagag ctctattacg
    29401 aaatcttaga ggaagcggta gagcgcctaa actgtgaaaa agtcatccta ggttgcacag
    29461 aattatcttt gatgcatgaa tttgctgaag ataatcatta cccagtgatc gatgctcaat
    29521 ctattttagc ggatcgaacg atcgaacgtg cattagctga aagaagcgag gcattggata
    29581 cagcatcgga aaagtaaaaa aattggattt ggggcaaata tcctaaaaga tatttggtcc
    29641 aaatcttttt gtaaaagaaa aagaaaactg gtaatgatac gcccgggatg atataatttt
    29701 attatgcaca atgtgagagg ggttcgtaaa tatgacagat aatttgcaat tagtcatcat
    29761 aacaggtatg agtggtgcag ggaaaacagt agctatccaa agttttgaag atatgggcta
    29821 tttttgtatc gataatatgc cgcctcgatt gattccaaaa ttctgggaat tgatcaaaga
    29881 atcaggtaaa gtcacaaaaa tggctttagg agtggatttg cgttctcgtt ccttctttga
    29941 agaaatccaa aacatgctga tcgaaatcga aaatacgaac ttcatcgaca cttctatctt
    30001 atttttagat gcttcagacg aagaactagt ggctcgctac aaagaaacaa gacgagcaca
    30061 tccaatggcg atggacggtt tgatcactga agggatacgt aaagaacggg cgatactaga
    30121 cgacttgaaa gcccaagctt ccgtgatcat tgatacgaca acattgacac cacgacaatt
    30181 acgtgaaaaa atcaatgagt cattcaaatc aaagggagac caaggatttc ggatcgaatt
    30241 tgtatcattt ggttttaaat acgggttgcc gatcgattcg gatattgtga tggatgtgcg
    30301 ttttttgccc aaccctcatt atatcccgga actaagacca ttgaccggaa aagatcagcc
    30361 agtctatgat tatgtgatgt cctttgatga aacgcaatca ttctaccata aatttttgga
    30421 tcttctggaa actgtattgc ctggatacat taaagaagga aaaagcagct tgacagttgc
    30481 aatcggctgt acaggcggtc aacaccgttc tgtggcattg actgaacgtt tggcaaatgc
    30541 tttagggaaa aactataaag tcaatgtgac acatcgggac aaggataaaa ggaaagagac
    30601 ggtgaaccgg tcgtgaaaat gaaaacctac cggataagaa aaccaaagat cgtagtggtc
    30661 ggcggtggca ctggtctgcc agttatcctg aaaagtttac gaaatcaagg agcagatatc
    30721 acagcagtag tgactgttgc agatgatggt ggaagcagcg gtgcaatcag agaatcgatc
    30781 gctatggctc ctcctggtga cttgagaaat gtcttagtgg cgttatcgga tatgccacaa
    30841 ttctatgaag atattttcca ataccgtttc aaaaaggaag atcagttttt agccaatcat
    30901 acgatcggta atctgatcat tgccgcagtt tccgagatgc ggggaagcac ttatgaggcg
    30961 attcaattat tagcaaaaat gatgcatgta gatggacatg tttatccttc ttcagaaact
    31021 cctttgacct tgcatgctgt ttttaaagac ggaacgactg cagtaggaga atctaaaatc
    31081 gcgatcaacc gtaaaaccat tgaccgtgtg tatgtctgca acacaaatga taaaagtgaa
    31141 gccaaagcgg ctcgaaaagt cgtttcagca attatggacg ccgacatggt cgttttggga
    31201 cccggaagtt tattcaccag tatccttcca aatttagtga taccagaaat cggcgaagca
    31261 atgctcaaga caactgctga aaccgtctat atctgtaata tcatgaccca aaaaggggaa
    31321 acggaacatt tcacagatgc cgatcatata cgtgttttac acaagcattt gaatcagcct
    31381 tttatcgata cagtattggt caatacggaa aaagtgcctg aagattatat ggacccagag
    31441 atctatgatg agtatctagt acaagtcgca cacgacttca acggattgag aaatgaagga
    31501 tgtcgagtga tttccaccga ctttttagaa ttgaaagatg gtggtgtctt ccacgatgga
    31561 gacaaagtag tagaagaatt gttccgttta gttttcggtt caaaatatta agcaatttat
    31621 tgttggagaa aggaggagaa taggatgtca tttgctgcag atgtgaagaa agaactaact
    31681 ggtttggaag ttcatcgaga acatgcgaaa gcggaattag ctgctttgct gcgaatgaac
    31741 ggctctttag gtattgtgaa ccagcagttt attttgaacg tccaaacaga aaatgctgca
    31801 attgccagac gtatctattc tcttttgaaa gatcattatc aggtacgaag tgagctactc
    31861 gttcgtaaaa aaatgaaatt aaaaaagaac aatgtctata tcgtccggtt gaagcaaggc
    31921 acaaaagatg tgttgatgga tcttgatatc atggatggta tgatgttcaa tggacacgtt
    31981 tcggacgaga ttatgggaaa ttcgcaaaaa atgcgttctt acttacgtgg tgcttttatg
    32041 gcctcaggtt cagtcaataa tccggaaacg agtcgttatc atttggaaat attttctatt
    32101 tatgaacagc ataaccaaga catttgcgat atgttaaatt attacggtct acatgctcga
    32161 acgcttgaac ggcgcaatgg ctatatttcg tatttaaaag gagcagaaaa aattgctgat
    32221 ttcttaacat tgattggtgc aaccaactca atgctccgat ttgaagatgt tcgaatcgta
    32281 cgggatatga gaaattcggt caatcgtcta gtcaattgtg agacagcaaa tctgaacaag
    32341 acgattgatg cggcttctaa acaaatcgaa aacatcgaat tgatcgaagc aaaggtcggt
    32401 ctacatgccc ttcctgaaaa acttcaggaa atcgcagaac ttcggcttca acatccagag
    32461 gtcagcttga aagaattagg ggaaatgatt ccctcaggtg caatatcaaa atcgggaatt
    32521 aatcaccgaa ttcgcaaaat aaatgaattt gcggaaaaac tgcgtgaaga agcagtttaa
    32581 tccaaagaaa aaactgatac atgaagcagg agatgcgaat gtatcagttt tttttaaaag
    32641 ctatacttgc ttttcttccg tcaaactata attccaactt tactggagta acataatgtt
    32701 gaaaggcttc tattgttttt taatacaatc gtataaaaag cggggagaca actgaatgaa
    32761 gattttagtt ttatacataa acttttgctt aatatagaag tcctgatata gataggatca
    32821 agtatttatc tataactgga gattaattaa aaactggaag gaactgctcg atcaaccttg
    32881 agaactgttt ttcttacttc tggtcaagat tctcgtggtt ggtggataag gatggttgat
    32941 aagttcattg gattagctag tcgaaaacaa ccaggtgtaa ttaatgtaga agttttaaca
    33001 aggggatgga gtgatttatt cagtgataat cataagttca taaatagtaa ttgggatgta
    33061 tggttggtat acgttatacc tgaacttgaa ctatcaagat ttggtttaga atttgagaat
    33121 cgatgtttat aaagggaggg caaaaaatgt gcttttttac aacttttact atcattatga
    33181 ttgcagtact ttttattttt ctagatatag caaagcgaaa tacagcattt ttattatatc
    33241 gggttttact tcgagcaggt ctcataacat ttatatcgat cgttggattt tttctattca
    33301 cagttattgt atttatttgg agaactacag caccaccatt gccagagatt acatatggag
    33361 aatttccgtt tagtcttgaa tatgaaatag atgaggaaag aattttgatt gaagatacgg
    33421 tgattgcaga atttatagga agttttagag ggaatgtgac aactcaacct agacgaagtt
    33481 ggagtataaa acttttaaat aatagtggag agttgaaagc atttcattat gaattcttaa
    33541 taatagaaag tgaagatgta acaatcactt taagtagtgg ctctgctgga tattttatga
    33601 atgatggtgg aagcaagcca cagctcacag tccgtgatcg tattgcaggt tttatgcatt
    33661 tttctcacta tgacttagaa gaagctcgta aaatacttgc agaatatggg atcacattaa
    33721 tcaattggga atatgcgcca ccgataagaa attttttcaa tgattattat tagtcttata
    33781 aaaaacagaa tgtaaaattt atgtgcgcga gtatttagtt ttccattttt tgtttgatag
    33841 atatatagca ttgttgaagc atgggatagt ggtgccaatt ttatcaatga ggttggtcag
    33901 gcagttaaca taattggtga tgctataaat ccatttaatt ggaattggag gaattaggtg
    33961 tggaaacagt gagattatgg atattcatga aaaattttcg ttcggctttg agatatgtta
    34021 ttctggaatc aaaatcaggt tattatctga ttgacacaga tcactatact ttttggggag
    34081 gctacctttt tccgattttt aattggataa tcccccataa ggttatgaaa attaacttgc
    34141 ctgcagaaga aataaataga ttaatactca acaaagattt acaaaggaaa agagagaaag
    34201 aacattctaa tgttgcttgg ataggtccag catttgcagt agtgacttct tcaattgtcg
    34261 gtcctatgct agagagtatt tatagtgatt tttctattgg aatacgttat ttatttgtta
    34321 ctttaagtat agctgttctt ttgtgcataa agggttatgt tagcaagaag aataaagata
    34381 ttttaacact aatcggtgta aacaatttat ctagtactaa aattatactg tttcctgaat
    34441 ctataaaaga aggatcaagg ttgttgataa tttttataat gcttatactg ttttctgttt
    34501 tatttggggt gatgtttata ga
//
LOCUS       DARPZF010000025        33449 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.026, whole genome shotgun sequence.
ACCESSION   DARPZF010000025 DARPZF010000000
VERSION     DARPZF010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.026"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            493..825
                     /locus_tag="SLE65_001541"
     CDS             493..825
                     /locus_tag="SLE65_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEI8448840.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            1416..1745
                     /locus_tag="SLE65_001542"
     CDS             1416..1745
                     /locus_tag="SLE65_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448841.1"
                     /translation="MIQKFAKMSKTAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVDDKCPVKISFSDIATIIEGIYYGEVDEEISSTKDLLDFLDKNKDTFIVLTDYEE
                     VTTNEKL"
     gene            1732..2073
                     /locus_tag="SLE65_001543"
     CDS             1732..2073
                     /locus_tag="SLE65_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HEI8448842.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLTDDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            2187..2426
                     /locus_tag="SLE65_001544"
     CDS             2187..2426
                     /locus_tag="SLE65_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448843.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            2493..2732
                     /locus_tag="SLE65_001545"
     CDS             2493..2732
                     /locus_tag="SLE65_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448844.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKMMKQKHLKRLSVMQYINDMKIT
                     GKEKACLLGSMKNFEQLRRTYVKTGSNCQLLLEVS"
     gene            2859..3548
                     /locus_tag="SLE65_001546"
     CDS             2859..3548
                     /locus_tag="SLE65_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEI8448845.1"
                     /translation="MNKNNKTLFNPYVGVIIVFLLFSYFAYQGYQKDKIAEKVDGVTK
                     TIHIQEQAKTYQDNLTSLTDISKRQLITNQKQALEKDLKGEIAGKLVFSSTGFILPVF
                     QGANSDTLSLGVASTYYLDTEMGNGNYILAGYNVDTPSVLLSDMTDLSEGEEIDLIDA
                     HYKYQYEVSKRGKISDYSQVVQSKENNSFLSLPKAGKKPLLTLLAFQANNMKKCDVIQ
                     CELVNVEKINK"
     gene            3554..4720
                     /locus_tag="SLE65_001547"
     CDS             3554..4720
                     /locus_tag="SLE65_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HEI8448846.1"
                     /translation="MSHIQELVEKLINKMSAIFLLLLVSILYLIWTVGLNPPTILFIY
                     DNAAQLVTFFVGCLFLLNLYKVKRNDLFFIAAGILFYLFFSFFRSYRGDTFYGDLIVP
                     TIIAIILIVKWTKFTVIDRSLYLVVFYVFLLVTVYRVFTEIPVPEGQSIWNPSNKLSD
                     IWINTNTIGSSLMTLALLITGFASSFGKWYMRLLSLPALILAGATIWVCQSKAALYAL
                     VIFIILEILPKKVFRNTHLSFWMYAAVSVLALPISYFAAMSDKVHLFTGREEIWRKFY
                     ETLGEKTGQIFVGMKPFFFHRGNQILGNHNTYHALVNHYGLIGFVLSIILLLSFLWLL
                     VRKRELTNGQLTFLWAFLAIMCQSFMEETLTTISWVPIVFLMLAMATHQYKTTR"
     gene            4802..5473
                     /locus_tag="SLE65_001548"
     CDS             4802..5473
                     /locus_tag="SLE65_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HEI8448847.1"
                     /translation="MKKWLFGFLGVALIVVCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            5526..7502
                     /locus_tag="SLE65_001549"
     CDS             5526..7502
                     /locus_tag="SLE65_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEI8448848.1"
                     /translation="MAINRYVKKAGMIVGMLGIIAGCFQGYRAYAEDVTQKTPPERVN
                     ITVHKLMYDQSTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGELVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGEEHSFQIGDAVNYQGTIHIPTDIAGGTDGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGAISAVVYFKKKA"
     gene            7515..8267
                     /locus_tag="SLE65_001550"
     CDS             7515..8267
                     /locus_tag="SLE65_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEI8448849.1"
                     /translation="MIIRHPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            8283..9044
                     /locus_tag="SLE65_001551"
     CDS             8283..9044
                     /locus_tag="SLE65_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448850.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGV
                     NGAKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLSSDQLKLISNGETKTIDQQT
                     GVFEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSE
                     ASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            9057..9317
                     /locus_tag="SLE65_001552"
     CDS             9057..9317
                     /locus_tag="SLE65_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448851.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            9314..11404
                     /locus_tag="SLE65_001553"
     CDS             9314..11404
                     /locus_tag="SLE65_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEI8448852.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLNNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTILAVSLLL
                     LVLATFGYAVLKFN"
     gene            complement(11440..13497)
                     /locus_tag="SLE65_001554"
     CDS             complement(11440..13497)
                     /locus_tag="SLE65_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEI8448853.1"
                     /translation="MKLLNPKTVIAIGTFAATVALAGSADAASTNVMYRLYNPNNHEH
                     FYTSSTKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVTSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNTLDSAYKGLKKKPAPTVNKTELQALYNQVKSTAKGDFTEGSWNNFQTAL
                     SNAKKVLDDSKASQTQVNNAKNSLDSAFKGLQHKPKPSEYAVTVRHMNRQTGTLLKEE
                     HVSVKAGTSYTAKARTDLTNFEAPQYQVNGNETQTQTINTNTTFTFYYDEVFLVEVKA
                     RPNKVSDTDPNIQELYNYSKSYPVVYGQSITIEAPMFTNFVLDPRESSSNTVTLNNVT
                     SNQGINFAYTHQYNVTVNHINVDTNAVLSTETQTVYEGDSFSTSWKNMTDQNYFLCRN
                     DDSSVTVDKNGQRVINNVDQNRTITFKYKNISLSDLNNYVRQKELAWLNSYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENINSFYLYVD
                     EILSDTGAVNAMVMWKDSAAHNANLLYNNQSIVGLSHAYEVSADGSLSSDNVFISANP
                     IFK"
     gene            complement(13642..13833)
                     /locus_tag="SLE65_001555"
     CDS             complement(13642..13833)
                     /locus_tag="SLE65_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448854.1"
                     /translation="MYADKEKIEWLLFETGKTAYEISKHSSVAESTIADLIKKKSAIE
                     KMRFDNAAKLTKYAESISS"
     gene            14021..14476
                     /locus_tag="SLE65_001556"
     CDS             14021..14476
                     /locus_tag="SLE65_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448855.1"
                     /translation="MKKLIMVFTSLIAMIVILGGCGSEKNKQDSQDNGVLKPGTVWKE
                     EVGGLVHNLKIIDDTTWEYSESVWHPEQVQITVEKLKDYKGLERYKVIDSGGVDLFIG
                     KTALIVSYNKDGLETFKFIPTNEKEHRDKSEILKEYSTKSGYKLQKTSE"
     gene            14473..14715
                     /locus_tag="SLE65_001557"
     CDS             14473..14715
                     /locus_tag="SLE65_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HEI8448856.1"
                     /translation="MIASLFIYPEGGIAVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            14733..15035
                     /locus_tag="SLE65_001558"
     CDS             14733..15035
                     /locus_tag="SLE65_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448857.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQGAATSLKNNLMIFAAVAA
                     VASIVLGGIFFFFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGMFGQTPQGL"
     gene            15104..17158
                     /locus_tag="SLE65_001559"
     CDS             15104..17158
                     /locus_tag="SLE65_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448858.1"
                     /translation="MYFTISGNTKKDKELIKKATKKVGKRTAFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVSQVSEVEVNDEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDLVEA
                     NEEPTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWERTKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCIE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMERHGQIQQELQAQIPKWKKEYEIQQQELKEQEEKQRQEEKEREQLELKKREQH
                     LAEQKVAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTAESSMENSKESDPSKAKEGSSDSTVHSNTSESSESNE
                     VK"
     gene            17158..19770
                     /locus_tag="SLE65_001560"
     CDS             17158..19770
                     /locus_tag="SLE65_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEI8448859.1"
                     /translation="MRIRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGSFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPENEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHKGK
                     KFHEERVKVGYRGFCEINFDCHLEQGDHVCLKYNHQGKQYVAWYEFSQKVLKDEEGKI
                     VYRKKRGETHLPELEKEAVLTLDEKKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSFENETAKKLLIQFYEEQATDRLQEYVEKLIKNEEISEMI
                     RKRLLLEAEKAVKE"
     gene            19767..22145
                     /locus_tag="SLE65_001561"
     CDS             19767..22145
                     /locus_tag="SLE65_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448860.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAVGKINGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGFGH
                     RKDITHDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTVE
                     DLTEKAKDTLEEKLDGTRAKEFAEAVKNPSEALEKQKEKASAVKEGLKDAYGEGQVNA
                     AVKANTTSEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEGQHGQLPKTDPEQYRY
                     KSNINSENEKRISDLPKRNQEVQTDEDSIDLPNDNGIEVGTEKSTKIGLPKTQNLPMK
                     DSRLNQFKENDQSFVHQSPAGTVQMKSSRLPENGNLTTVSYNLAESGETENASVQNIV
                     TKEAAPKPINKVHNGYRPANVAFTAPTKINVTRETKNRNNELKEQLLKDIKP"
     gene            22206..22748
                     /locus_tag="SLE65_001562"
     CDS             22206..22748
                     /locus_tag="SLE65_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448861.1"
                     /translation="MEDILIATFITALGAFLTIFVVTIKGFKDTDSLQKDHQSILDGQ
                     KTHTESIIVHLSEGFTYLKDAMPTFTVKLTEIFHSVEQISSELKEQRQQKDRQLGSLN
                     FRQETIQESLENVNRLNDEMQRVHLENEELRAQNYDLIQKKRNLEQKIVELKEENRQL
                     NYQLRRGKNRSRDLGNELEL"
     gene            22826..23158
                     /locus_tag="SLE65_001563"
     CDS             22826..23158
                     /locus_tag="SLE65_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448862.1"
                     /translation="MDKYIHMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWLAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            23159..23752
                     /locus_tag="SLE65_001564"
     CDS             23159..23752
                     /locus_tag="SLE65_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448863.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            23774..25798
                     /locus_tag="SLE65_001565"
     CDS             23774..25798
                     /locus_tag="SLE65_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HEI8448864.1"
                     /translation="MLDVIKTAFSTQSNQKVIDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLAFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            25798..26997
                     /locus_tag="SLE65_001566"
     CDS             25798..26997
                     /locus_tag="SLE65_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEI8448865.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLL
                     PSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPN
                     SKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSII
                     NTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEF
                     RPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQE
                     FANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLP
                     FLNSSKK"
     gene            27013..27657
                     /locus_tag="SLE65_001567"
     CDS             27013..27657
                     /locus_tag="SLE65_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448866.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTYKIEEVAK
                     NASDKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPVDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            27668..28474
                     /locus_tag="SLE65_001568"
     CDS             27668..28474
                     /locus_tag="SLE65_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448867.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIFYIH
                     EDKVKDHVKDEDYEQHAINYKVKGYKKEQKAAQKQIESFQATIDLNEELVKKLKDQLP
                     YQVAEDQENTENKINSYQQEIETSKTQMKDQEESIQKLQEKIDRMTKENI"
     gene            28497..28726
                     /locus_tag="SLE65_001569"
                     /pseudo
     CDS             28497..28726
                     /locus_tag="SLE65_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            28747..29820
                     /locus_tag="SLE65_001570"
     CDS             28747..29820
                     /locus_tag="SLE65_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4199 domain-containing protein"
                     /protein_id="HEI8448868.1"
                     /translation="MKKTYQKFLWISYIVLFIVGFLVSVSVIVGTLFLLFSDEDLVLK
                     GLMSTLSCVMLLYLCIQINEIMPPHWQEKKKEFKEEIEIKSNDWIEYTWLPLKRNSKR
                     KEFWALQLWPIGKLFIYMASLMVTLIGYLVVVYGVAYYLLSEPKQIAASNIFTAVMTL
                     MCVMCFSIFSYLLVQFIRQNLTMSKLFKSLLDLLILGSMLTTLTDRFEQSEKTVEGIK
                     NFLTTIDQFINGYMYLFEVGFILTLFGCVFIKLIKRSIEKEMVIDLIPTLSGYEYYVD
                     FGKYEELIHTDIVHTSIHEVTVKGIRSTLKDGQETKTIDRRKEVYNFYKVEASLRYGI
                     GKLRLDGSNIQQNKPYVLGKVVI"
     gene            29864..30133
                     /locus_tag="SLE65_001571"
     CDS             29864..30133
                     /locus_tag="SLE65_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448869.1"
                     /translation="MILLYRIVLIVGTELKILKKEQLFKVKEHHNQLLCIKTGTMNIQ
                     YRTEYLELTNQTDFLSIREQHKQEKLMATYSQLIDEWEQFKESKT"
     gene            30409..30684
                     /locus_tag="SLE65_001572"
     CDS             30409..30684
                     /locus_tag="SLE65_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448870.1"
                     /translation="MEVKIRDIDEKTIQRIDRRCIELSERTGTKWSRNRYLKVLIEND
                     FDHELMDHRKDQFDRLLEKFVDIQTYNTKILEEYIATNNQLIALLIE"
     gene            30726..31148
                     /locus_tag="SLE65_001573"
     CDS             30726..31148
                     /locus_tag="SLE65_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448871.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKPINESVHARVDPFDPTKFLKR"
     gene            31168..32760
                     /locus_tag="SLE65_001574"
     CDS             31168..32760
                     /locus_tag="SLE65_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448872.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPDE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWHYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKSLKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIESMD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            32781..33116
                     /locus_tag="SLE65_001575"
     CDS             32781..33116
                     /locus_tag="SLE65_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448873.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYSATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            33262..>33449
                     /locus_tag="SLE65_001576"
     CDS             33262..>33449
                     /locus_tag="SLE65_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448874.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT        12009 a         5153 c         6834 g         9453 t
ORIGIN      
        1 ttagttgttt taaatttaat tgtctgctat gcttgtgatg aattgatttt cgttctgcac
       61 ttttggacga taaatttgga caattgaaaa tacaaaaaaa agaaaggccc tgtgagactc
      121 ggaaggctac caaccttcgt cgacgtccac aggtggcatt aagtctatac cccttaatgc
      181 gtttaccttt cagtgttacg gtattacccg taacggattt agtataacag atattcaaaa
      241 gtgataccac tttttttggc tgtgttaagg ttaaaaatac gtgatattac gatgaatcta
      301 tgcctaagca taatgttata aaaatgtccg tggggctctt tgccgtatga cgaacgctga
      361 aattagaggg aacgcatgtt tgaatgcgtt ccctcttttt tgtttgtcat gaacgaaaat
      421 caattctcta tttttgaaaa ataacaagaa aaacttgtta aaaatattta aagtaagtgg
      481 gtggattatt ttatgtcata tacaggaatt ttgagtctcg aagatatttg tcactacggt
      541 aaacggtgta ccgctacaga aaagatcacg aagaaactat caactggtca aagtaaaacc
      601 gttgtgcagt gtaagaaata tataatccag aaagacaaag tctcagaaga aatgatttat
      661 tacattggga aacaaaaaca aataatttta aaagatccta tccctttaaa agagctatat
      721 ccaacaatca aacatgttta tgaccaaaac ggtgtactga ttggtcgaag aaaaaatgga
      781 gtcttgcgtt gtaccgcaaa agggatgggg cgtttaatca gctgaattga tcattctcat
      841 aacttgtatt ttatcgtttt tcgcttgctt gaaaatattg tcgagacttc taaaggaact
      901 tagaatcact agaaaaataa ggagtagact tgatctatca acaattccct tcggggagtg
      961 acggggtagg tttttacgat tggtaacgta aaaaattggt caatcgagta aatgcccttg
     1021 tttggatagt ggtgaaatga atttgtgtaa ataatatgca cagagtaaac aagagggaat
     1081 ttagaagtta gacaagttag aatagcgcct agattaatca tgagcagcta ctaagggatc
     1141 taggctttga cgcaaactca tggaataagg agtaggtctt ctcgtaatgg ggaggacgca
     1201 caagaaattg tgtcgtgtgc tgcagtacat gtagatactt gcgaggacgt tgatcattgg
     1261 atcaatcgag catttaccgc tgtctactag ggtttctcgt ttcggacgcc ataaacgagt
     1321 cgatttattt tatatatttt tgagtgaacg aaaaacgata aagatattcg ttatgaagta
     1381 aaactaattt agtagatagc aaaggtggta gaggaatgat tcaaaaattt gcgaaaatga
     1441 gtaaaactgc atggattgaa aagcttgaaa atgacttgag tgtcatgcga ttagctccaa
     1501 agaaattcaa acgagagatt gcagaaaaag aagcaatttt gtcggtattg aatgcggtag
     1561 acgataaatg tccagtaaaa attagttttt cagatatagc aacaattatc gaaggtattt
     1621 attatggtga agttgatgaa gagatatctt ctacaaaaga tttattagat tttttggata
     1681 aaaacaaaga tacctttata gtactaactg attatgagga ggttacaaca aatgaaaaat
     1741 tatgatccga atatacgatt gggcacacat acgattaagg tttctttcca acgttgggat
     1801 tacaaaggat ttgtgacgtt tagaagaggc ggaaattgta aaggattaga tgttttagca
     1861 ttagacgagg atgatttata cgatcaaaca ttgactgata atccaattgg attcggcttg
     1921 ctacctgaag atgatgaagg taatgaatgg tttaaaatga cgcttacgga tgataatgga
     1981 gacgaattat ctgttgaaga tacttggtca tatttgagtg attatattgt cagcgttgaa
     2041 atcattgaat ttgtagcgga taaagaagaa taaaaactgg aggaataaat tttacagata
     2101 aaggcttaga aggagtcacg acgaataata aaaaggtagt attaccttag gcattgagta
     2161 aggaatttat ttaggaggaa aattagatgg cgcgaccagt tttagaggcg atggatatgg
     2221 atactttgac aaaaggaagg tatgtacagc tgttagctcg tggttattca cctaaagatg
     2281 tattcaaatc cctgtctaaa ggaacagata tggaaaaaga aagattacga aaagaattcg
     2341 attattggag aacccataat ggaatcaagg atttgaaacc agcacggcca gtaattaaac
     2401 gaaagaaaaa gataacccaa gactgaagtg tagagcgtat gtgatcatag gcttttttat
     2461 ttttgcaaaa aacaagaaag gtaggaaaac tcatgaatta tgaagaaatc gaaaacagaa
     2521 aaaaagtgtc gaaagaaatg gaagaaaagt tgctaaaaat gatgaaacaa aaacacctta
     2581 aaagattatc tgtcatgcaa tatatcaatg atatgaagat aacaggaaaa gagaaagctt
     2641 gtttgttagg ttcaatgaaa aactttgaac agttgaggcg aacttatgta aaaacaggtt
     2701 ccaattgcca actattatta gaagtttctt gacgattatg atatgaaaat gatcaattat
     2761 gatgtggcat tgttattgaa taaaaagaat agtaaaattt aacatggttt atcttggtta
     2821 gatgtaggta aattaattca tatatagaag gtagatagat gaataaaaac aataaaactt
     2881 tatttaatcc ttacgtgggc gtaatcattg tttttcttct ttttagttat tttgcttatc
     2941 aaggttatca aaaggacaaa atcgctgaaa aagtagatgg tgtaacaaaa acaatccata
     3001 ttcaggaaca ggctaaaacc tatcaagata atttaaccag tttaacggat atttctaaga
     3061 gacaactgat tactaatcaa aaacaggcat tagaaaagga tctcaaaggt gaaattgctg
     3121 gaaaacttgt tttttcttct acaggattta ttctccctgt ttttcaagga gcgaatagcg
     3181 acacgcttag tttaggagta gcttctactt attatctaga tactgaaatg ggaaatggaa
     3241 attatattct tgctggttat aacgtagata caccaagcgt tttattatcc gatatgactg
     3301 atttatctga aggagaagaa attgatctaa tcgatgctca ttacaagtat cagtatgaag
     3361 tctccaaaag aggaaaaatt tctgattaca gccaggtagt tcaatctaag gaaaacaatt
     3421 cctttttatc cttgccaaaa gcaggtaaaa aaccactact cacactgtta gcctttcaag
     3481 caaataatat gaaaaagtgc gatgtgatcc agtgtgaatt agtcaatgta gaaaaaatca
     3541 ataaataagg gaagtgagtc acattcaaga acttgtagaa aaattgatca ataaaatgag
     3601 tgccattttt ctgttactgt tggtatccat tctatattta atatggacgg tggggttaaa
     3661 tcctcctacg atattattta tttatgataa tgctgcacag ttagtgacgt ttttcgtagg
     3721 ctgtttgttt cttttgaatc tgtacaaggt aaagagaaac gatctattct tcattgcagc
     3781 aggcattctt ttttaccttt tcttttcttt ttttagaagc taccgaggag atactttcta
     3841 tggtgatctg atcgttccga caattattgc tattattttg attgtaaaat ggacgaaatt
     3901 tactgtaatt gatcgtagct tgtatcttgt agtattctat gtctttttac tcgtaacggt
     3961 ttatcgagta tttactgaga taccagtacc agaaggacaa agtatttgga atccatcgaa
     4021 caaattatca gatatttgga tcaatacaaa tacgataggt agttctttaa tgacattagc
     4081 ccttcttatc acaggatttg ctagttcatt tggaaaatgg tacatgcgat tgctatcatt
     4141 accagcgttg attcttgctg gggcaacgat ttgggtttgc caatcgaaag cagcattata
     4201 tgcgcttgtt atcttcatta tcttagaaat tttacctaag aaggtttttc gaaatacaca
     4261 cttgtccttt tggatgtatg cagcagtttc ggttctagct ttaccgattt cttattttgc
     4321 tgcaatgtca gacaaagttc acttatttac aggacgagaa gaaatttggc gcaaattcta
     4381 tgaaacatta ggcgaaaaaa caggacaaat atttgtaggg atgaaacctt tctttttcca
     4441 tagaggaaat cagattctag gtaatcataa tacgtatcac gcactcgtca atcactatgg
     4501 attgattggt tttgttctat cgattattct tttgcttagt ttcttatggt tgctcgtaag
     4561 aaaacgtgag ctgacaaatg gacaactaac attcttgtgg gcttttttag cgatcatgtg
     4621 tcaatcgttc atggaagaaa cattaacgac aatcagttgg gtgccaattg tattcttaat
     4681 gttagcaatg gctacacacc aatataaaac caccagataa atgaaataga atagtaataa
     4741 gagaaaacac tttttcgttg tgaaaaagtg ttttttgttt tgtctgaaag gaggcagatg
     4801 gatgaaaaaa tggttatttg gttttttagg agtcgcttta atcgtcgttt gcagtgtgtt
     4861 tggctatgtt agctaccaaa aacatgaagg agaggtgttt aagcaaaata tagaaaaaaa
     4921 gatgcccgta gatcaaatca atgcacacgc aaagagttat aaggaggatg caacgaacgt
     4981 caataatgat atgtctttgg ggcaaatgtt gtccatacaa aaagaagcaa tcgaaatggg
     5041 cgtcaataaa caagtatttg cacaaattca gattcctgca cttggtttag cattgccaat
     5101 ttttaaaggg gcaaatcaat acactttgag tcttggagcg gctacttatt tttatgaaga
     5161 tgccgaaatg ggtaaaggaa actatgtcct agcaggtcat aacatggaaa tgccaggtgt
     5221 tttattttct gatattcaaa agttgtcatt aggggaggtg atggacttag ttagtaacga
     5281 tggcgtctat cgttacaagg taacgcgtaa atttatcgta cctgagtact ttaaattaat
     5341 cgatggcgtt cctgaagaga actctttctt gtctttacca aagaaaggag agaaaccctt
     5401 attaacgttg tttacttgtg tttatacgtc acaaggaaaa gaaagatacg tggtacaggg
     5461 agagctacaa taacaagaat ttaatcaacg cgagtcgttg aaatatgaaa tgaggagagt
     5521 aaaaaatggc aataaatcgg tatgtaaaaa aagctggaat gattgttgga atgttaggaa
     5581 tcattgcagg ctgctttcag gggtatcgag cttatgcaga agatgtcacg caaaaaacgc
     5641 caccagaaag ggtcaatatc acggttcata aattaatgta cgatcaaagt acgcaattga
     5701 acgttgatat tgacggaatc aaaaatgatg gttatacgca cgatcaatat cctacaggtg
     5761 taacgaaata caacaaggca gattatggtg atgttgagtt tacgttagga aatattacgg
     5821 atcaagtatt accgactgaa gattctgatc taaccaacgc gaaagtggac gaaatcgtta
     5881 aagatgtaga agacaaggga tctaacagtg agtacgttaa gaatgcaacc aataaaatta
     5941 cttcagctgt agatgaaaat ggtgagatca cttttgctga tcaaccagcc tatgtcaatt
     6001 ccaaagggaa tgtatatgtg gtttatgaaa gtaaatccgc tgctggatta gtcacacaaa
     6061 aagcaaaacc aatggttgtg attgcgccaa tgacagacaa cacaggatca ggatttttaa
     6121 aagatattca tttgtatcca aagaacattg tttctaagtt gagttttgaa ttaacgaaat
     6181 ttggtgacga tggcacagct caaagcaaac aaacaccttt aaaaggggca aaatttgagt
     6241 tatacaaggg cgaacctgga aaaggaacaa aattaggaga gcttgtatcg gatgatcaag
     6301 gaaagctgac tgcaactgat ttgacgttag gaaaatacta ctttgtggaa gttccttcag
     6361 aagttgtagt tggatcagat caagaaccaa cagcagacca atatttgtta ggcgcagacg
     6421 ctcgcaacga tgcgcacaat aagttaacct ttgaaattac gaatgacggc gtgacaagtg
     6481 atttaaaagc ttcctacgtg aactataaag caccagtgat cgataaaaca gtgacaaatg
     6541 gaacaggaga agaacattct ttccaaattg gtgacgcagt gaattatcaa ggtacaattc
     6601 atatccctac agatatcgca ggtggaacag atgggattac agtaaatggt gtaaaaagtg
     6661 aaacttctcc ttacagtgta tttaaatggg gcgacacagc aggtaaagga ctttcttatg
     6721 ttgctgaaaa agcagatatt aaagtaacaa ataatgatgg ttcagtcgta ttaaaagaaa
     6781 atactgacta taaaatcgaa aattctgata gtggttttgt gatcgatttt atcgtaaata
     6841 atggacaagt aagtgataca gttgcgaatt tacatggtca agatctaaaa atgacttata
     6901 acatgtttgt gaatgatagt gctgaaatcg caaatccatt aacaaatagc gtggatttcg
     6961 tttataacaa taatccattt aatcaggaag aacaccacga aaaaacgaaa gctgacgttg
     7021 tgacttatgg cgcaaaattc ttaaaagtcg atagcggcct atttggaaca ggtatcaaag
     7081 caacaccgct tgaaggcgca gaatttgcag ctaagaatgc agaaggtaag tactacggtg
     7141 gacttactga tacagataaa gatggtgtca aagaagcagt ttgggtagac gatgtagcaa
     7201 atgcagcaat cctaaaatca gataaagagg gtcattttga aatcactggt ttaactgaag
     7261 gagattactc actggaagaa acaaaagctc ctgaaaacta tcaaaaatta acaaaagaga
     7321 tctctttcaa agtagacaaa gattcataca aagaagaaaa ccgaatcacg atcaaaaata
     7381 atcaaaaagc ttccgtacca atgactggta gcaacggttt ccaatcttac gtattgatct
     7441 cttgcttgtt gcttggggca ggcgcaattt ctgcagttgt ttactttaag aagaaagcct
     7501 agaaggatca gctaatgatt atcagacacc ctaagaaaaa gcgaatcatg ggtaaatgga
     7561 tcattgcttt ctggttactt tcagctgttg gtgtcttact tttgatgcct gctgaagcga
     7621 gcgtggcgaa ataccaacaa aatcagcaga ttgccgcaat cgatcgaaca ggaacggcag
     7681 cagaaacgga ttcttctttg gatgttgcta agattgagtt aggcgatcct gttggtattc
     7741 ttacaattcc aagtatttct ttaaaactac caatttatga cggaacttcc gacaaaattt
     7801 tagagaatgg tgtagggatt acggaaggaa ctggcgatat tacaggagga aacggtaaaa
     7861 atcctttaat cgcagggcac agtggacttt ataaagataa tcttttcgat gatttgcctt
     7921 cagttaaaaa gggagaaaag ttttatatca aagttgatgg tgagcagcac gcttatcaaa
     7981 tcgatcggat tgaggaagtg caaaaagacg aactacaaag aaactttgtc acttacttag
     8041 aaccaaatcc caatgaagat cgagtaacgc taatgacatg tacgcctaag gggatcaaca
     8101 cacaccgttt cctagtgtat gggaagcgag taacctttac aaaatcagaa ttaaaagatg
     8161 aagaaaataa gaaacaaaaa ttatcttgga aatggctttt aggaagtact gtttttcttt
     8221 cagtcatgat cattggttcg ctatttgttt ataaaaagaa aaaataaagg agggtaacca
     8281 acatgagaaa tagaaaatgg ctatttgttt gtgcagccgc tcttttttct ttcactgcct
     8341 acacacagtt gacgtttgca gacagacaag aaagcacgga tagcacagaa caaacaatcc
     8401 aaacgtcaga tagcagcacg attcaaagca gcgatgaaac cgtcgattcg tcaacagttg
     8461 attcttcaga agaacctaaa attgctgaag acgatcaaat agtcaaacag accattcacg
     8521 ttcaaaaaat tatttcttcc gaacaattag acaaccaggg gcaaaagctt gaaaaacaag
     8581 aaggagtaaa tggcgcgaag ttttctgttt atgatgtatc ggacatttta caaaagatgg
     8641 atgttaagga tctcactact gaccaaattg aatcccaatt aaaagatcga gtgaaaaaac
     8701 tatccagtga tcaactgaag ctaatttcta atggagaaac aaagacaatt gatcaacaaa
     8761 caggtgtctt tgaattctcg gtagaagtac aggcaaatca gaaacaagct tattatattg
     8821 tcaatgaatc aagtcctgaa aacatttcta atagcgagga tattttgcta ttaacacctg
     8881 tttctgataa aaatggtgaa ttcttaaagg atgtgtggat ttatcctaaa tcagaagctt
     8941 cgcaacctaa agaagaagta aaaaaaatcg tatctactgg cgtaaagaaa aacttctttg
     9001 agaattgttg ggattttgtt actcacttgt tttctagaga ttaaggaaga aataaaatga
     9061 aactgatcaa attattatta ttcaattttt cttgtttaac cgcagtcttt ttgtactgcg
     9121 gtttattatt ttctaaacta tctattttgc caagctacca actataccta atgaggattt
     9181 taaacatacc agctgcttcc atgccgctag atattatgga aaagctcatt aggaatccat
     9241 tatttactac gatcaatttg atcgttattg tcggaatttc actagtcatt tataaaaaag
     9301 aggggatgaa gggatgaatt ttaaacactc gtggacaaga cggttaaaat atgtttttcc
     9361 cataatgatg atgttaggta cattgtttgg gttaaaaaca gccaatgtct ttgctgaaaa
     9421 agttattgtc gatccgtcaa atccaatcca gaacgtaaag aataatttta ttattccaaa
     9481 agatgttcct aatgcaaaaa caaatattac tgtaaacgga gcgtcaaaag tttacaaata
     9541 tcatgttgat gccaacaaag gtggttttac agacgactac gtaggattag tggagggaaa
     9601 caaaaatata cgctatcctt ctttccaaaa agaatacggt gaaacaaacc ttgttttaga
     9661 aggcgtaaca accaacacca aagtcaatat tgactatgga aaaatcggta cgtataacgg
     9721 gaaaaaagtc aatatcaagc tagttctatc taatattcac ttatactcgg atacgttgcc
     9781 gtggaatcta ctagataaca actatacaaa aactcatttt cgagacgatg gctataaaaa
     9841 tacgaatggt gcaatgagta aatctaaaaa aagaacagta ctttggatct cagacaatct
     9901 tttctcagga attgtttacc attcaacaca aatgaatgtg cagctagtag ccacatatga
     9961 ggacggtagc cccgttcaat tttcaggaga tacatttatc agttttaact ctttgaaccc
    10021 tgcaggagga aaaagcacgg atcttaaagg agaatatgcc cactatgaca aaatgaatac
    10081 gacagattgg tatgtcagaa aagatacggt tctttcagaa tttaaatctt tctacaacaa
    10141 tctgaacgtg gtaggtggcc acccaggagg aagctctaag ctgacacaag cggataatga
    10201 tttcaataat ttgcatgata aattaggaga tccgaagttt ggtcaaggta ctgtgtcctt
    10261 taaaatatct gaagcaaatc cgacgtttgt gattggttct tctaatgttc aaacctggtt
    10321 tactttatct tctgcgacaa tctttagtgt tgttcctgat caacctgaaa aaacaggggt
    10381 tgataaaaat ggaaataacg tgaacgataa aatgttgcaa gtaggagaca cgattcaata
    10441 tcgaatcaaa cagaaggtga atcgattagg agtggattta ctagcggttt acgatcgatt
    10501 tgagttaatc gataatttac caaaagaagt aaattacgtc gatgcacacg ttgaaagtgg
    10561 tacaaataaa aaattcgatg tatctggtga agtgacctat gacaaaacaa aacaccaggt
    10621 aaaatatgca gcgaaagctg atacattaaa aaatcgaatg aagtataacg gcgaaactta
    10681 cgaattagtg atcaatgtaa aagtcaatga attggccaat caaaatagtg tagccaaaaa
    10741 tcagggaacg tcgatcatta ataaagtaga aaaggataca aatatcatta ccgtttattt
    10801 ccctaaaatt ccagtgaaag aagtacaaca aaatggaaaa gatgtaaacg gacgaaatga
    10861 cggtaagaag ggtacgccga cagctccttt aaacgcagga tctgaagtac aatatctagt
    10921 cacacaaaaa tggcacacaa aaggcgtaga cgctgcgtca gatcactaca aacaatttag
    10981 tattcaagat ccaattgaag ctcgtttgac atataaagaa ggttctgcgc aagtaataga
    11041 taagagtaaa ggaaaagata ttacttctga aggcacacta acctatgata gcaattcaag
    11101 aacgctgaag tgggaagctt ccgctgactt cttaaataac aatcttttag atggacgaga
    11161 aattcagctg atatttacag ctaaaactcc attacaatca gaaaaaaata ttgataacca
    11221 agccgtagta gcagtagata atgtttctaa taaaacaaat gttgtgacaa ttggggttga
    11281 tcctaacttg ccacaagtta ttgttcctaa aacaggttct acacatttag taacgatttt
    11341 agcggtcagc ttactattac ttgtgttagc aacttttggc tacgcagttc tgaagttcaa
    11401 ttaaacaaaa aaacaaggct gaaaatcagc cttgtttttc tatttgaaaa tgggattggc
    11461 actaataaat acgttgtctg aagaaagtga tccgtctgca gaaacttcat aagcatggga
    11521 taaaccaacg atactttgat tgttgtaaag caagtttgcg ttatgagcag cgctatcttt
    11581 ccacataacc atagcattta ctgctcctgt atctgaaagg atctcgtcaa cgtaaaggta
    11641 gaaactattg atattttctc ctttagcacc gtagcagcct aagctttcta agagatcttg
    11701 gaaagtaccg ccgccaggtc ggtaatgact gaagcttact tgtaattctt ttgcacgaat
    11761 atctgcagct tgttgaacga tatcattgaa ttgcattggg gcaacgccat tttgttgacg
    11821 gtagctattt aaccaagcaa gttctttttg acgcacatag ttgtttaaat cacttagtga
    11881 gatatttttg tatttgaaag tgatcgttcg attttggtca acattattga ttacacgttg
    11941 tccattttta tcaacggtaa cagatgaatc gtcatttcta cacaagaagt agttttgatc
    12001 ggtcatattt ttccaagaag tagagaaact atctccctcg taaaccgttt gtgtttcagt
    12061 agataaaaca gcgtttgtgt caacgtttat atggttcaca gtgacgttgt attgatgagt
    12121 ataggcaaaa ttgattcctt gattacttgt aacgttgttt aaagtcacag tgttgctaga
    12181 gctttctcta ggatcaagaa caaaattagt gaacataggt gcttcaattg tgatgctttg
    12241 tccataaacg acgggataac tcttactgta attatagagt tcttggatat ttggatcagt
    12301 atccgagact ttatttggac gagctttcac ttcaactaga aagacttcat catagtaaaa
    12361 agtaaatgtg gtatttgtgt taatcgtttg tgtttgtgtt tcattcccat ttacttgata
    12421 ctgtggtgct tcaaagttag tcaagtcggt tctagctttt gcagtgtaac ttgtaccagc
    12481 ttttactgag acatgttctt cttttagcag cgttccagtt tgtcgattca tatgacggac
    12541 agttaccgca tattctgaag gtttaggttt gtgttgtaac cctttaaatg cagaatcaag
    12601 actattttta gcattattta cttgggtttg agaagcttta gaatcgtcta gtactttttt
    12661 agcattggat aaagcagtct gaaaattatt ccaagatcct tctgtaaaat ctcctttagc
    12721 agttgatttt acttggttgt acaaggcttg taattccgtt ttgttcacag taggagctgg
    12781 ttttttcttt aatcccttgt aagcagaatc taatgtgttt ttggcactat ccacttgttt
    12841 ttgagtcgct tttgagtcat ttaacacttt tttagcattg tttaaagcgg tttggaatgc
    12901 gttccaggta ttgtcggtat agtcaccttt tttagttccc ttaacgctcg tataaagagc
    12961 ttctaaagct gatttattca ctttgggttt agaggtgtca gcaccatacc aaccaatacc
    13021 ttcgtatttc cagccatagt ctttggttaa ccattgtact tctttccaac ttgcagtgta
    13081 gtgatgcgaa ccagaggtaa cacctggaag gaaaaggcgg tagatcggtt tattattttt
    13141 ttcggcagaa cgccaggcag gcccttcata agtccaaccg taatttttgg tcaaccattt
    13201 cacttcatcc caactagctg tgtaatggtg atcacgaagg cctttattgt ataaacgata
    13261 gacaaggtgg ccaccgctag tcggtgcttc ccaagcgggg ccttcataat taccccactt
    13321 aattttcact aggtgatcac gttcttttgt gctagaggtg taaaaatgtt catggttatt
    13381 tggattataa aggcgataca tgacgttagt tgaagcagcg tcagcagatc cagcaagagc
    13441 aactgtggca gcaaatgttc caatagctat aacagttttt gggtttaata atttcatgtt
    13501 ttcaactccc tattaaatga ttaaatattt tgtttacatt cataatatac cacggtatac
    13561 cgaggtagtc aacggtatac cgtggaaatt ttgaaataaa aaagccgccc tatgaagagt
    13621 gtaaggatgg ctgtttatat gctatgaaga aatggattcg gcgtatttgg ttagtttggc
    13681 agcattatca aatcgcattt tttcaatcgc actttttttc tttattaaat ccgcaattgt
    13741 tgattctgcg actgaagaat gtttgctaat ttcatatgct gtcttgccag tttcaaatag
    13801 taaccattcg attttctctt tatcagcgta cattgcaatg ctccctcttg attttttctt
    13861 tattatagct cttttttgta ataaatcaca atatcaagag gaaaagtttc tatagaaagg
    13921 tgggaaatta tgagtatccg ttccccgtgt atcaaaatga ggtttgttgc tactttcgtt
    13981 atttaatata ctaaaataaa acaacgaaag aaggaataga atgaaaaagt taataatggt
    14041 atttacttcg ttgattgcca tgattgttat tttaggtgga tgtggtagtg aaaaaaataa
    14101 gcaagatagt caagataatg gcgtgttaaa accaggaaca gtgtggaaag aagaagtagg
    14161 cggacttgtt cataatttaa aaattataga tgatacaaca tgggaatatt ccgaaagtgt
    14221 ttggcatcct gaacaagtac aaataacagt tgagaagcta aaagactata aaggattaga
    14281 aagatataag gtaatcgatt caggtggagt agatttattc ataggtaaaa cagccttaat
    14341 agtttcctat aacaaagacg gtttagaaac gtttaaattt attccaacaa acgaaaaaga
    14401 acatcgagat aaaagtgaaa tattaaaaga atacagtact aaatctggat acaagttaca
    14461 aaagactagc gagtgattgc tagtcttttt atttatcctg aaggaggaat cgcagtggca
    14521 aaagctaaaa cgccatttga aaaagccgcg tctaaaatct tagaacgtcg cggtgtatct
    14581 gaaacacagt ggaaacaaga agtccttgaa aaagcacaat ttgacctatt acggggaaaa
    14641 gacaaggact tagaaggata tatctatcaa cgtgaacgtg aaaagcttgt tttcgatgaa
    14701 attattaaac actaaaagga gcgaacaatt ttatgtttga atcaattaca atgaattttt
    14761 taacacaacc gaaagtagta gctgcggttg atatttttag agcattacaa ggtgcagcaa
    14821 ctagtttaaa aaacaatctg atgatttttg cggctgtagc tgccgttgcc tccattgttc
    14881 ttggggggat tttcttcttc tttggccgaa gaggagctga aaacgggaag atgcacgtag
    14941 gttatgtatt gatgggggta ggagttatat tagctgccgc ctctattgtg gtttcgttat
    15001 ttggaatgtt tggacaaacc ccacagggac tataaaaaat aaatagaagg agtaaaaagt
    15061 acgtggctac tttttactcc ttttttatga aaggagaata ctcatgtact ttacgatttc
    15121 aggcaatacc aaaaaagata aagagttaat aaaaaaagca acgaagaaag tgggaaagcg
    15181 tactgccttt ttaccgaaaa caattaaata ttctgtcatt gaaacggaag aacagctaca
    15241 tgtgttagga caagtgttag aacaagagaa tcaatcttct gttaaattga ctctcacgtt
    15301 acatgataaa gaaggaaaaa tagaaaaggc tggcacagaa tacgtttttg gcccactgga
    15361 ttatcaaatt tcagaaggtt tttatcctac attgatggat ttgatccgcc ttgatgtgtt
    15421 taaggaaacg gatgaaacca tgagtgtgga agagtcttat cgaaacgaaa aactgctaca
    15481 agttttagaa gaagagttag agagcgacca aagaaaagtg agtcaagtga gtgaagtcga
    15541 agtaaatgat gaagtaccat gggaacgacc aatctttcca aagaaggagt caaaagaaaa
    15601 agagacagtc tatgttgacg aacaagctga tattccgact cagaaatcga tatttgagga
    15661 agagaacgat gtaatgggtc aattggaggt agatcccttt gaagaaacaa tggaggatga
    15721 agagacggcc gaagtagaag ttgatctagt tgaagctaat gaagagccaa catggactga
    15781 aggggattct caggaatata ttgaaccact tatcagtgaa gaagtagaga aaaacgaaac
    15841 agagatacaa aaggcaactg tatttgatta tattttggat caatatccgc cagagcatga
    15901 atggatgaaa gaaaaaaata aattattttt aaatgagctt tattcgaaat atcaattacc
    15961 ccaaacctat caagcatttt tagagagtaa agaagaatta atctcacagg gtaaaggcac
    16021 acttttagaa cagttagagt ctgttcaatc aacaaattgg catgagcttg cacaagaaga
    16081 tttattagcc acttttgaag aacgtcaaca agaaacagat caagaaataa atgagtatgc
    16141 gacggaacag tcatctaatt gggagagaac aaaagaggaa ctaaataaag aagaacaacg
    16201 agtgattgaa gaagaagtac aaaaaattaa agagcgatac gaaaagaaac gcgacaatgc
    16261 gtattccttg tgtatagaga aaattaataa ctttactaaa actaatcaag aagctttatc
    16321 gaaagaaaaa gaaaacttgt taaaagaacg tataaaagaa cgaaaagaag agttctaccg
    16381 aggtttacgt acagataagc taaagattag caaagaatta aatgaacaac tgaataaact
    16441 ttatcaaaca acgactgaag ttcttatgga aagacacggg cagatccagc aagaattaca
    16501 agcacaaatt ccaaaatgga aaaaagagta tgaaattcaa caacaagaat tgaaagaaca
    16561 agaagaaaaa caacgacaag aagaaaaaga gcgcgaacaa ttagaactaa aaaaacgtga
    16621 gcagcatctt gcagaacaaa aagtggcgat agaaaaacaa cggttagagc aagaaaagga
    16681 aaaagaagca gctgctcgta aggaacgtca agaacaaatg gatacattgc gacaagcaca
    16741 gttgaattat ctagcacaac ctcaaccagt agctgctgtt caaacgccag tgaacaacca
    16801 agcaaattta actccttcac cacagcgttc ctttaacgga tggatggtgg gatgtattgc
    16861 aagtttaagc ttgcttctag gtggaggaac agtatttgct tttaatcata tcaatcaatc
    16921 ttcacaggca gattctgtag ccacaacggc gtcaatcaag gaagaagccc aggaacaagc
    16981 aagaaaagag tatgaacaac aattggaaga attattgaat cgtaccaatc agtcaacagc
    17041 agagtcaagt atggaaaata gcaaagagag tgatcctagt aaggctaaag aaggatcaag
    17101 cgattcaact gtacactcaa acacttccga aagttcagaa tcaaatgagg tgaaataatg
    17161 cgtattagag aaacaacgag acgaaaagac aaacgattca atttagaaaa gaataggtat
    17221 ctttctcatt tctatcgcta tactccttca ggagaagagc taccagaaaa acatgacaaa
    17281 cgtatttctc aaaagatttt ttatagtggc ttagcttatc ttcctttaaa ctatgttgtt
    17341 acaagaatac cagaagcatt tcatcgattt gagattattc caggaagttt acaaggagtg
    17401 aatatttttc agttacaaga aatgccgcag ttattccatt ttgattcaac tggtttttgg
    17461 aatcctttga ccccaacaac aagtttaggc acacgtttag ttgtttctac gatttgtgtt
    17521 gttccagctg tacttatggg attgaaaatg gacatgtggt ttcgtccgct agcagatggg
    17581 caaaaaggag ataaccgatt aaaaacgtta aaggaaatcc aacaaattta tccgcaaata
    17641 ccagaatcaa agggaagttt tcctggttat ggcggaatac caattactca ttataaaaaa
    17701 tactggtata ttcagacgga tacagtaaat acttgtattg ttggtacttc ccgctcaggg
    17761 aaaggccaga tagaagtttt agcaaccatt gacaatttgt cgcgtgcaga aagacaaagt
    17821 tcaatggttg ttaatgatcc aaaaacagaa ttatatgttg ctagtaaaga tgaactagaa
    17881 gctagagggt atgatgtgta tgcctttaat atcaccgatc cactgcaatc aatgagtgat
    17941 aatccattgg cactcattgt gaaatactgg aagcgaggag acatagacac cgcaacacag
    18001 ttaaccaata cttttacgaa tacgatttat tatgatgcaa atgcttcaga caataaatac
    18061 tttaacgaaa atgcgcagaa agctgtcaat gcgcttattt ttgcgttatt ggaacaagcg
    18121 gatcaaacag gggattactc caaattaaca ccaaataatc tcgttgaact actttcagaa
    18181 attggcggtt ttaattatta tccagatcct gagaatgaat tcaagcagct caatgcctta
    18241 gatgagttca tgaatcagtt accccctgga aatatagcaa aaaaacaata tggggcaaca
    18301 aaaattggat ctgataaagc gaaagggaat atcttgtcta cggcaattac aggattgaat
    18361 ccatttaccc taacgaaaat tgcgaagatg acttctcaat cgaccattga ttacaagtcc
    18421 attggttttc cgaagtattt ggatctcaaa ttacatgaaa gcctattaaa tcaacgcatt
    18481 gtcgtggaat tttatcataa gggaaagaaa tttcacgagg aacgagtcaa agttggctat
    18541 cgtggttttt gtgaaatcaa ctttgattgt catttagagc agggagatca tgtttgctta
    18601 aaatacaatc atcaaggaaa acaatatgtt gcttggtatg agttttctca aaaagtattg
    18661 aaagacgaag agggaaaaat cgtttatcga aaaaaacgag gagaaactca tttgccagaa
    18721 ctagaaaaag aagccgttct aacattagat gagaagaaaa gtaacctatt agtagagtct
    18781 attcggatgc actataccga taaaccaatg gctattttta tgttaacgcc tgattatgat
    18841 ccatctaacc atatcattgt tagcatcttt cttagtcagt tgtataaaga attatctacg
    18901 caatgtgtta agactaaagg agataaatgt caccgtagga ttcattttat tttagatgaa
    18961 tttggaaata tgccaccgat ggacaacatg gaaggaatca tgacggttac ggcaggtcgt
    19021 aatatgttat gggatctgtt tattcaatct tatcagcaac tttatgcgaa gtatggagaa
    19081 caaaacgcag cgattatcaa agaaaattgt cagacacata tttatattat gtcgacagat
    19141 gataatacca tcgaagaatt ttctaaaaaa gtggggaata agacggttga acaagagaac
    19201 agtaccatca attcattagg tatgaatact catatcaatc gcaatgttga ttcagatcgt
    19261 atcttaactc ctgaaagaat ttctactttt ttagaaggtg aaacgattgt actcgctcct
    19321 ttaaaacgac aagatttgaa aggtcataaa atacggccgt atcctatttt taatcatggg
    19381 gaaacgaatc ttccttatgc ttatcaatat attgaagatt tcaatccatc gtgggatatc
    19441 aatgatatag acatacattg tacacatgcg gacttggatc ttaaggcttt acaaattgat
    19501 tatgattatt tcctaccaga tgaatatgct agaaatctct atcatggact gcatgatcaa
    19561 ttagaagaaa aaaacgaaga aaatatgttt tataaaatcg ttcaatcttt tgagaatgag
    19621 acggctaaaa aattgttaat tcaattttac gaagaacaag caacggatcg tcttcaagaa
    19681 tatgttgaaa agttgatcaa aaatgaagaa atttctgaaa tgattaggaa acggctgtta
    19741 ttggaagctg aaaaggcggt gaaagaatga tcattggagg aattttctct ggcatagccg
    19801 actggtggtc aggtttattc ggagaagggg atgcagatcc caaaaccgta acgaaagtct
    19861 tacaagatta tggtaattat ctgcagtatc aagatgtatt cagttggatt tgtaatactt
    19921 ttttatgggg attgatcaaa gggttatata atctcaatac tttattagaa aaaacaattt
    19981 atcaaagctt tgatttaaaa gacttattga acgccgctgg tgttaatgaa ctatttcaaa
    20041 gtttgattag taaggtattg gctctttttt gtgtcgtcac attaatttat ttaggcttga
    20101 aattttttat gagtaaacac ccaccgaaag tcaaaaatat cttggttaat ttatttatgg
    20161 ccatgatctt gatttttggt ggtagttctt taatcgatga agggttaaat atcagtaaaa
    20221 acttttatgg agacgtcact gcagcaaata aagcagataa aacgggttca cctgcttttc
    20281 aaattattca aaataatgtg attgatgtca gtacattact agcgactgac ccgaataaag
    20341 tagaatcctt accaacagat aaaagaaatg ctttaacagc gaaaaatttc aaaacagcga
    20401 atatcaatgg gattattaca cctgatcaag ctaagaaaat gtctgaatca agtgatatta
    20461 gtacagtaca aaaagatcgg ttaaaggcat tacagtatcg actagagtta gacgataatg
    20521 ggaaagaaat ccctgttcaa attagtgatg aaggtttagc aaaatatgtg tatacgtcag
    20581 gctatcgtcg atacattagt agtccaggga ttattttggc tggggaatct tctttgtcgg
    20641 tagcctattt atttattttg tttacaatcg ttacttgcat tattgagcta gtatttaaaa
    20701 aattctattt agtaattgcc gcgtcaacgg actttgagac aggacaacgg atgaaaagtg
    20761 cgatagaaga tatttctcaa tccttcttgt tattggcgtt tacgatttta gaattacgaa
    20821 tctatacatt aatgctttca ggtatcggtg atttgcatgc ggtaggaaag atcaatggat
    20881 tcttgtatgt tgttgcttta attgtgctaa ctattgcgct attcaaaggc tctcaatcgg
    20941 ttacgaagat tttcggtgtt gatacgagtc tgaaaaacgg cagcaattct cttcttagca
    21001 tgtttgcctt aggaaatatt gcgaaaaatg tgggtagcgg agctaaaaac cttgcaagtg
    21061 ctggtaagag tggtttaagc catttaaatg atattcgtaa gaatggattt ggccatcgaa
    21121 aagatattac ccatgataac ggggaagaac aatcagacga taaagctaca actgtaccta
    21181 atagtaagaa gacagtttcc gaaatgttcg ggaaagcgaa aaatggtgtt tctaaagccg
    21241 cagaaggtct tggttacgtc aatgaacgtg ggttaaaagg aacagttgaa gatcttacag
    21301 aaaaagccaa agacacctta gaagagaaat tagacggcac gagagctaaa gaatttgctg
    21361 aagctgtgaa gaatccatcc gaagcactag aaaaacaaaa agaaaaagct tcagcagtca
    21421 aagaaggact aaaagatgcg tatggtgaag gacaagtcaa tgcagcagtg aaggcaaata
    21481 caacaagtga aaaagaaaat caagaaggtg cagcgattcc ttcagccaaa gatcaccaag
    21541 atgagttaca ttctaacgaa aattcgatcg gagaaaaaga ttcagaagaa ggacaacatg
    21601 gtcagttacc aaaaaccgat ccagaacaat atcgttataa atctaacatt aattctgaaa
    21661 acgaaaaacg catttcagat ttaccaaaac gaaatcaaga agtacaaacg gatgaggatt
    21721 ccatcgatct gccaaatgat aatggcatcg aagttggaac tgaaaaatca acgaaaattg
    21781 gtttgcctaa gacacaaaat ttaccaatga aagatagtcg tttgaatcaa ttcaaagaga
    21841 atgatcaaag ctttgttcat caatcacctg caggtactgt tcaaatgaaa tcaagtcgtt
    21901 tgcctgaaaa tggaaatctg acaactgttt cttacaattt agctgaaagt ggtgaaacag
    21961 agaatgcgtc cgttcaaaat attgtgacaa aagaagctgc acctaagcca atcaataaag
    22021 ttcataatgg atacagacca gcaaacgtag catttactgc accgacaaaa ataaatgtga
    22081 caagagaaac taaaaacagg aacaatgaat tgaaagaaca actattgaag gatatcaaac
    22141 cataaaaggc ctatttaagg gcctttttct ttataaaaca agtttaaaat ggaaaggaga
    22201 aaattgtgga ggatatttta atagctacgt ttataactgc actgggagca tttttaacga
    22261 tatttgtggt gactattaaa ggatttaaag atacggatag tttacaaaaa gatcatcagt
    22321 ctattttaga tggtcaaaaa acacataccg aaagcattat tgtacacctt tcagaaggat
    22381 tcacttattt gaaagatgct atgcccacat tcacagtaaa attaacggaa atatttcatt
    22441 ctgttgagca aatatcgtca gaattgaaag agcaaagaca acaaaaagat cgtcaacttg
    22501 gctcacttaa ttttaggcaa gaaacgatac aagaatcatt ggagaatgta aatcgattaa
    22561 acgatgaaat gcaacgagtt catttggaaa atgaagaatt acgcgcacaa aattatgatt
    22621 taattcaaaa gaaaagaaat ctggaacaaa aaattgttga attaaaagaa gaaaatcgtc
    22681 aattgaatta tcaattacga cgaggaaaaa atcgttctcg tgatttagga aatgaattag
    22741 agttgtaata tttagaaaaa cgctgtgaga aatcacagtg ttttttattt ctaaaaatac
    22801 aaaatataag gggtatggtt atattatgga taaatacatt catatgaaaa atcctccaag
    22861 atttagtggg gaatggaagt ttttcgcctt tttcttttta gatctattaa cgcttggtgg
    22921 ctgctttttt tgggcgaaaa tagtcaataa tcttgtccac ttaccactct tttttgcact
    22981 cttgaattat ggattatggc ttgcgatagc gttagtgatt gtttggcgac cctataataa
    23041 ccctggtcaa cgccaaattt ttgcgattat cgaatctatt ttctttacgg ataagaacca
    23101 ctatcatgcg ttagatccta accgaaatta tcatggtacg tataaggagg atgaataaat
    23161 gcgagtcaaa ggacaaaatt cagttgataa gaaatccatt ttgcagtttg gaaaaccaga
    23221 agagcgctct atcttggact tatttccata taaatcctgt acagaagagg gagtcttaat
    23281 tactagagaa gatcattttc agcgttatta tcgtgtcgtt tccactgacg tggagggatt
    23341 aaatgaacaa gagaaactag aacgaatgaa tcagttgacc accgtcatgc gtacgtatgt
    23401 gccaacaatt aagttagtta gtttgaccac agagacggat ctaacggaac aaatcgtgca
    23461 aaagcggcag ttattagata aaaatcgtat ggaacagtca ctaggaagaa atctacagcg
    23521 attaagaaaa tatgaaaaga aattagtaga ggagatccag gaattaaaac gggcagaaca
    23581 agaacgtcct gacttaagct tctttttcgt tattgaagga aagacaatca aggatttaca
    23641 aactagaaat cgtcagttaa tgcgatctag tggcatttta gggttaaaac cactctacaa
    23701 aaaagaattg attaagattc tttatcgaat gaacaacatg aatgacgaat aaaaaagatg
    23761 gaggaaatga ttcatgctag atgtgataaa aacagctttt tcaacgcaaa gtaatcaaaa
    23821 ggtgattgat ccattaaaac aacttggtaa tcgtgaaata gagattttaa aatcaaaagg
    23881 ttatgattta gatttcttaa aacaagtgat gccacaaggt gggttgaatt ttgatgaaga
    23941 atatgtgacc tatggaaatg gttattcacg atgtgtgaca gtttatcatt acacaaaaaa
    24001 tcctactctt ttttggttgg ccaatctcat gaacaatcct catacagtgg ccacactaga
    24061 tgttagcaca gatgaaaagc aaaaagtgat tgatcaaatc aaccgcgcat tagatgaatt
    24121 aaatgatcga tcagataatg aacgaaaagc gactgaccga aataaaagtg cggaagaata
    24181 cctggaacta gcggaatatg cccgaaaatt gacttctaat ggggaaattt ctaaacaagt
    24241 caaagtgaga gtacatgttt acggaaatac gatccaagaa gtggatgaac gggcgcagga
    24301 actgatcgaa aatctaaaag ggatggatta tcgtgcggtg acttatctgc ataaaaccaa
    24361 acgagattgg caatcgatgt ttaccatgtt cgatgaacaa gctgaatggt ttggaaatat
    24421 caaagggcaa tcacttccat cgttaaacat tggcggagga ttcccgttcc accaccaaac
    24481 gctaaaagat ccaggaggca cacaatatgg ggaaaccatg acaggcggcc catttgtctg
    24541 gaatgccacg tataaaaata gtgtacgttt atctaccaat accttgcttc taggaatgat
    24601 gggagctggt aaatcgaccg ttcttaaaat gatcgcggaa gcccatttag ctgcaggaga
    24661 ctttatttgg ggctttgaaa agggaaaaga ctttattcct ttcttaaagg aatataacgg
    24721 tattatggtg cgtttagacg gatctgacgg gatgatcaat cctttagaga tctttgccac
    24781 acggacgtat gatgaagcat ccagtttata tgacgatggt tcagtcaaag atttgaagat
    24841 caatgaagca gcgtcctatc aaacgcactt agacaaagta gtctatcagg tacagttagt
    24901 gagtcctcag ctaaaaggaa cgatgaaagc agaattcaag acctacttga atcgttttta
    24961 tgaagagtat ggaacagtac cacgcggttt tacttcctca aattcgcgtt caaatactga
    25021 tacgcaagtc acagggaaag atccagaagc ttatccgacg ttcaaagaat ttttagcctt
    25081 tttaggacaa ctggaactac caggggcttc ccaagagaaa aagaatcgga aagaagaaat
    25141 ggagtctatc gtggaatcct tatgtgagac ttatggcatg atttttgatg gtcatagtac
    25201 gattcgacac cttgaccaac aacagttggt cttttttgac attgactcta ttacaggcct
    25261 agatcgaggg gtacaacaat gtcagatgta catggccatg acgttgattt ggaatcaggc
    25321 attgattcaa ggacgaagac aacgacgctt aattaaagaa aaacaaatgg aagaacaaga
    25381 cttcaaacgc ttcttggcga tgattgatga gtgccataat gcgattaatc cagatttcat
    25441 tgaaacggta aattatgtca caaacttcca acgagaaatg cgtaaagtag aagcaatgac
    25501 tgttttagct acacaatccc cacaagaaat ggtgccagaa aatatgtctt ctgataactt
    25561 ctcgaaactg aagaaagtct ttgaattttc ttctacgaag atctttatgc gtatggatga
    25621 atctatttta cgtcatatag aaggattagt tggtaaatca atgacgaact cagaattaga
    25681 atccattcct caacaaaatc aaggagacgc tgtgatcaat tttggctcaa aagaaaccat
    25741 tcgtgttcat tttagtccga acaaacgtca attaaaattg tttgatggag gaaaataatg
    25801 gaaaaccaaa atgaaagttt aatcaaacag tatgttaagc gtcgtgcaaa gcggcgctta
    25861 tttttgtggg tgtttggtac ttctgcaggt ttgattacta tattgatcac tgtgtttgtg
    25921 accctttttc taatacttgc ggcaggttct attgataatt ctgattcaag tagtggtggc
    25981 gaagctttta caggagaata ttcggaaggc ttacccattt ataaagaaat caaaggaaga
    26041 ggcccttttt ctgatgagat tgcgcaatat gctgtaggtg cagcagtgaa gtataaatta
    26101 ttaccaagtg tgatcctttc gcaatacggt tatgaatcag cgtttggtac gtcggcgtcc
    26161 gcaagaaatg atctcaatta ttttgggatt acgtggtttg atgggtgtct gtttcctaaa
    26221 ggaactgcgc gtggaattgg tggcattgaa ggtggctggt acatgaagtt tcccaactca
    26281 aaagctgcct tctcctatta cggctttatg gtagccacac aatcaaattt taatgcttgt
    26341 gtcggaaata aaagccctgg cgcaagctta ttgatcttag gacgaggagg gtatgccgcc
    26401 gcaggaatta ctgaagacag tgcctattat aaaaattgta tgtctattat taatacaaat
    26461 aaattgatgg agtacgatga gtttgcgatt aaacactgga gagaaggcgg cggaactggt
    26521 ggtacgatta caggaagctg gggcaatcca ttcccaggaa gtagcttaga taaaaattcg
    26581 ttcagtggag gacaactttt tgggaaaaat ccaggaggag aattccgacc taacgggttc
    26641 catgatggac tagactttgg ttcagtcgat catccaggaa gtgagattca tgcggttcat
    26701 ggcggaaaag tcgtgtacgt tggcaatcct ggtatttcag gtttgggtgc gtgtgtgatc
    26761 gtgattaatt acgatggctt gaatatggtg tatcaagaat ttgcaaatag tacaggaaat
    26821 tctcgagtga aagtaggcga tcaagtgaaa gttggtcaag taattgggat acgagataca
    26881 gcacacttgc atttaggatt tactcgaatg gattggcgtc aagcacaagg acatgcattc
    26941 attgatgatg gtacatggat cgatccgtta ccatttttga atagcagcaa aaaatagatc
    27001 aggagaaaaa atatggaaaa taaaacctta aaaatcgtct taacagctgc aattagcgtt
    27061 agtttaatcg gcaatattgc gttgttttgg cagcttaaag aagaacaaga gacaaatacc
    27121 tataaaattg aagaagtggc taaaaacgcg tctgataagc tcaaaaaaaa ttcttctgaa
    27181 gcacaggcga agattgacaa gttaaatcaa accatcaatg agaaaaacca agaaatcgat
    27241 cagctgaagc aacaagatgg cacaaaagca aaagaggaag taactgaagc acaaagaaag
    27301 acggcagaag agttcggtca attggccatt gataaatcat taagcagaaa tgaattaacg
    27361 gaaaaactaa aagatgtcgc aacccaagaa gtgatcgaca aattaagtcc tgtagacgat
    27421 gatcaccaac atgatgatta cggaagttac tcttttacat taggtgacgt gcaaacttac
    27481 gctcaaacaa gcagtgtaaa agaggaacaa aattttgtcg tatttgttga ttatacaatc
    27541 ggcaatcctc aattcaaaga tgtcaaacca caaaaaataa aaggtggatt aactgtcact
    27601 gaaaaacaag tagatggtca atggaaagtc acagacttta gttatttcac tcgttaggag
    27661 gaagaaaatg agtaagaaaa aaggagcaag acaacgtttt aaaaaacgaa aaagttatct
    27721 tagatggctg gggatcttta tgattctcgg ctttttgatt cttgctagtc cgatttacac
    27781 acataaaaag gtagacatac cagatgaagt aagcacgaac gcatttttaa acacgaagga
    27841 actgacgatg gtttcaaaag aaaaaggagc gaaccagcaa ttagtttttg aatttgcgat
    27901 cgacgatgaa gatcagagct tattaaaaga actagctaat cttaattatc gtgtagaagt
    27961 aaagacagct aaaggggatt atcaagcaat aaaagccaaa gtgatcaagg tgtctgatga
    28021 ttattttgta gtgaagttag cacatgtacc agaagaatat attgctatgc gattaactat
    28081 tattcctgaa aaaattgatc caaaggtgga tatgcaagaa ccgcaagatc tgatttttta
    28141 tattcacgaa gataaggtca aagatcacgt gaaagacgaa gattatgaac aacatgcgat
    28201 caattacaaa gtgaaaggat acaagaaaga acaaaaagca gcacaaaaac aaattgaatc
    28261 cttccaagca accattgatt tgaatgaaga attagtgaag aaactaaaag atcaattgcc
    28321 ttatcaagtc gcagaagatc aggaaaatac tgaaaataag attaatagtt accagcaaga
    28381 aattgaaaca tcgaaaacgc aaatgaaaga tcaagaagag agcattcaaa aacttcaaga
    28441 aaaaattgat cgtatgacaa aagaaaatat ttagaagaat aggtggagta aaagaaatga
    28501 agcgagcgaa cttggtcggc aaagatactt tcgctgagca gaaagtattg attaaagcct
    28561 atctcaaagt tgtaaaagct aaagaaatat gtcaagaagt gaattatcta acacaacaat
    28621 atctgagttg aagaatggta gaaagagttt agatacctta aaattcagat catttgaagc
    28681 tctatatata gctgctaaaa aatattttac agctgataat aaataaaaaa ttaaggtggg
    28741 ttctatgtga aaaaaacgta tcaaaagttt ttatggatta gctatatcgt cctatttatc
    28801 gttgggtttc tcgtcagtgt gtccgtgatc gtcggaacgc tttttctttt gttctctgac
    28861 gaagatctgg tacttaaggg gttaatgagt acgttatcgt gtgtcatgtt actttattta
    28921 tgtatacaga tcaacgaaat tatgccccct cattggcaag aaaagaagaa agaatttaag
    28981 gaagaaatcg aaataaaatc caatgactgg attgaataca catggcttcc tctgaaaaga
    29041 aatagcaaac gaaaggaatt ttgggcattg caattatggc caataggaaa actttttatt
    29101 tatatggctt cacttatggt tactttaatc ggttatttgg tggtggtcta tggggtggcc
    29161 tattacttgt taagtgagcc aaaacagatc gcggcgtcaa atattttcac ggcagtaatg
    29221 acattaatgt gtgtcatgtg cttttctatt tttagttact tactcgtcca atttatcagg
    29281 caaaatttaa caatgagtaa acttttcaaa agtttattgg acttacttat cttaggcagt
    29341 atgttaacga ctctaacaga tcggttcgaa caatctgaaa aaacggtaga ggggataaag
    29401 aacttcttaa cgacgattga tcaatttata aatggatata tgtatttgtt tgaagtaggc
    29461 tttattctca ctttgtttgg ttgtgtattt ataaaactca ttaaaagatc aatcgaaaaa
    29521 gaaatggtta ttgatctaat tccgacgctg agcggctatg agtattacgt tgattttgga
    29581 aagtatgagg agttgatcca tacggatatc gttcacacga gtatccatga agtaaccgtt
    29641 aagggcatca gatctacttt aaaagatgga caggagacga aaacaatcga ccgaagaaaa
    29701 gaggtctaca atttttataa agttgaagca agtctacgat atggcattgg gaaattgagg
    29761 ttagatggga gtaatattca acaaaacaaa ccatatgttt taggaaaagt ggtgatttag
    29821 aacttcctat gaaagatgaa taaataagga gaatcttttg aaaatgattc ttctttacag
    29881 aattgtgctt atagttggca cggagttaaa aatcttaaag aaggagcagt tattcaaagt
    29941 gaaagaacat cataatcagt tactatgtat taaaacgggt acgatgaaca ttcaataccg
    30001 aacagaatat ttagaattaa cgaatcaaac tgattttttg tcgattcgag agcaacataa
    30061 gcaagaaaaa ttaatggcta cttatagcca attgattgat gagtgggaac aattcaagga
    30121 atctaaaaca taaaattcca tttaaacacc ttatttttta aagagcataa ggaaacgtgt
    30181 acccactttc aaaataaagt gggtagatag gctgtgccta tcacgtttct gaaaaaaata
    30241 aatgacccca aaattttcaa tttatgtgta ggtttatggg tagcaaaaat atgaatgtgg
    30301 gcagcaaaaa gttcatttgt gggtagtaaa attcaaatgt gtgtagcaat gtgtgtagct
    30361 acacacattg ctacacacgc tataacatat agtgaaaagg agatatttat ggaagtaaaa
    30421 ataagagata ttgatgaaaa aacgattcaa agaattgacc gaagatgtat tgaattaagt
    30481 gaacgcaccg ggactaaatg gagccgaaat cgatacctaa aagttttgat tgaaaatgat
    30541 tttgaccatg aacttatgga tcatagaaaa gatcaatttg atcggttgtt agaaaaattt
    30601 gtggatattc aaacttataa tacgaaaatt ttagaagaat atattgcaac aaataatcaa
    30661 ttaatcgcct tgttaattga ataataaaaa tagtattgtg aatttataaa aggaggaaat
    30721 caattttggc aaaagcaaca agaaaacatg tatatcttta cgatatgcat atcgaagtac
    30781 ttgatgaaat aatttctact catgaagata tatctaatta tagtgaagca gtcagacatt
    30841 tgtgtatgat gtatgatcca aaaatcgaag aaaaaataaa tccaattcaa attaaattga
    30901 atgcaatggg aaaagaaatt tctatattaa ccgaaatggt ttcagagttt gcggatcttc
    30961 atttgaaaga tacaggaata ctaattggta caaattcaac tgtctatcaa gaagcaaaag
    31021 agcgtgtgga agggaaaata aaagcgaatc aaacgaaaaa gtattctcct aagatcaaga
    31081 aaccaataaa tgaatctgtt catgccagag tagacccgtt tgatccaaca aagtttttaa
    31141 aaagataaaa agtagaaggg gaacatgatg aataaatcgc ctgcagtcat tctcacttgt
    31201 caatttacct tgcccaataa aaaatctttt tcaacataca ttgattatat gacaagagaa
    31261 aaagcgctgg aagaaaagga acgacgcacg ccggacgaag aacaggaact gcaacgaatc
    31321 aagaatgctt tagaggattt ttatattcct gaaggagaaa ctttttcgga gagtaagaca
    31381 gataaagaat tcagtgaaac gtcgaatgaa gctcaatcgt tgatggaaca tggaatcaat
    31441 tttgacaagt tagaggaaca agattttacc aaatatcttt cttatatgac ccgtcactat
    31501 gcgttagaac aaaagaaaga actgacgcaa agggaacaaa aagaatacca acggttgaac
    31561 caagcaatga aaaaatatca aacagagcca cataaaaaag cttcaggaaa tcttcctgga
    31621 gttttttcta tggcttcaga cgaagtgaaa ggaagtgatc tgaaggagat caaacaaatc
    31681 ttccaaagag ggcaacaaaa aggctcaatc atttatcaag atgttgtctc tcacgacaat
    31741 tcgtatcttg aaaaaatggg cttgtacgat cccaaaacag ataccttaga tgaagaagga
    31801 ttaaaagcag ctggaagaaa aatgatggag acattattcg agaaagaaca attgaatgaa
    31861 acaggttact ggatggcaac gattcaccgt aacactaagc atatccatat tcattttgca
    31921 gttgttgaaa aagaaaatac gcgtaaacct tacacggagg ttgaaaatgg tgtgagttat
    31981 atcgtaccga aaggtaagag aagacaagca acattagacg caatgaagac caattatgta
    32041 catgagttag aacgtttttc ttatgaaaag gatcgaatga ttggtatgga gaaacgaaat
    32101 ttattgacgc ggaaaagtga tttgcgtaac accttaacaa aagtggtaaa agagccagcg
    32161 cgttacgatc gacacgcaat gaacttatta aatgaagtat ataaaaccct acctgacaaa
    32221 cgttcggaat ggcattatgg ggatgaaaaa cgaaccaaac tttcaccata cacaagagag
    32281 aaactcgatg agttaaccaa atatgtgtta acaaaagaac ctgaatatca agaatatata
    32341 cagatttcaa aatcattgaa agaagaagca aaaagtcttt atggggaaag caagagagaa
    32401 tcaaaggatg cagaaaaaaa tgctctcttt gatttgaaga agcgcacagg aaatgccatt
    32461 ctaacagaac tgaagaaaca ggatagtcaa ataaaacctt taatagaaag tatggatcag
    32521 atgcaatcta tttacaatga acgatccttt cgaacgctta aacagttacc aacgaatgaa
    32581 tacaaatata gttacgaaga attcatgaag cgcaggaaac aattccaaca aagagttgtc
    32641 acgcaacgga gtttgcgtca attaaatcga acgattaatg cccatgaaga aaaataccac
    32701 gcaagtaaag cctacgaaga gcaacaacga agaattcaaa tggaacaaga aagacagtaa
    32761 agacagtagg aggaatagca atgaaacaat atttagatca atggaaagtt atagaaggat
    32821 cattaagaga agaacgaatc gaacaacttc ccgattgttt agaaaaagag catttgtttc
    32881 agataagaga aatgttgaga aacgaacagt ttgatccaaa tcaattttta gtcgttgagt
    32941 actcagctac tggtgtgtac tgttgtaatc atgtgaaggg tgaaaaatat tttatcattc
    33001 aagaatatga gggcaagtta gcgccttatt atactacttg ggaaatgaat gaagagggga
    33061 tcaataactt cccgtgtaaa agcattgaag agtctatttc actcacagaa tgttagttgt
    33121 taagtgaata aaagaagtaa aagagtcctg aacgtaattg tccaggactc tttttttcaa
    33181 tgaattgttt tccgccaatt caatgagtgg tgcgatttgc gactacatta tatcaaaaga
    33241 aagagaaggg aggaagaaga aatggcttat tcaacgattg gagttgttgt tgaaaaaagc
    33301 agagacaatc tcgtttttgt gacagaaatt caaacgggca gagcttttgt cgtcacagac
    33361 aaagcggcaa aagcgtatca aagtggcgat attttaacgt taaatctgac tacgaagacg
    33421 ttcgtcgatg cggcagaaga ttatccatt
//
LOCUS       DARPZF010000026        32662 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.027, whole genome shotgun sequence.
ACCESSION   DARPZF010000026 DARPZF010000000
VERSION     DARPZF010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.027"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            162..392
                     /locus_tag="SLE65_001577"
     CDS             162..392
                     /locus_tag="SLE65_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEI8448875.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            489..1790
                     /gene="murA"
                     /locus_tag="SLE65_001578"
     CDS             489..1790
                     /gene="murA"
                     /locus_tag="SLE65_001578"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEI8448876.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1803..1979
                     /locus_tag="SLE65_001579"
     CDS             1803..1979
                     /locus_tag="SLE65_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEI8448877.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2114..2410
                     /gene="yidD"
                     /locus_tag="SLE65_001580"
     CDS             2114..2410
                     /gene="yidD"
                     /locus_tag="SLE65_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEI8448878.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2595..3062
                     /locus_tag="SLE65_001581"
     CDS             2595..3062
                     /locus_tag="SLE65_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8448879.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3147..4031
                     /locus_tag="SLE65_001582"
     CDS             3147..4031
                     /locus_tag="SLE65_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEI8448880.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4145..4381
                     /locus_tag="SLE65_001583"
     CDS             4145..4381
                     /locus_tag="SLE65_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEI8448881.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4469..4549
                     /locus_tag="SLE65_001584"
     tRNA            4469..4549
                     /locus_tag="SLE65_001584"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4503..4505,aa:Tyr,seq:gta)
     gene            4556..4627
                     /locus_tag="SLE65_001585"
     tRNA            4556..4627
                     /locus_tag="SLE65_001585"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4588..4590,aa:Gln,seq:ttg)
     gene            4752..4922
                     /locus_tag="SLE65_001586"
     CDS             4752..4922
                     /locus_tag="SLE65_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448882.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVRVKSKRP
                     TNHTKKWMAKNR"
     gene            5142..5849
                     /locus_tag="SLE65_001587"
     CDS             5142..5849
                     /locus_tag="SLE65_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8448883.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5908..6552)
                     /locus_tag="SLE65_001588"
     CDS             complement(5908..6552)
                     /locus_tag="SLE65_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEI8448884.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDEAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGIPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6678..6965
                     /locus_tag="SLE65_001589"
     CDS             6678..6965
                     /locus_tag="SLE65_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448885.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7073..7393
                     /locus_tag="SLE65_001590"
     CDS             7073..7393
                     /locus_tag="SLE65_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8448886.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7474..8787
                     /locus_tag="SLE65_001591"
     CDS             7474..8787
                     /locus_tag="SLE65_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEI8448887.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLSNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKIL"
     gene            8784..9503
                     /locus_tag="SLE65_001592"
     CDS             8784..9503
                     /locus_tag="SLE65_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEI8448888.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVNSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQIAQPKIIRTISLAR"
     gene            9631..10182
                     /gene="raiA"
                     /locus_tag="SLE65_001593"
     CDS             9631..10182
                     /gene="raiA"
                     /locus_tag="SLE65_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEI8448889.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTANAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10404..12938
                     /gene="secA"
                     /locus_tag="SLE65_001594"
     CDS             10404..12938
                     /gene="secA"
                     /locus_tag="SLE65_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEI8448890.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            13064..14165
                     /gene="prfB"
                     /locus_tag="SLE65_001595"
     CDS             join(13064..13135,13137..14165)
                     /gene="prfB"
                     /locus_tag="SLE65_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEI8448891.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14270..14956
                     /gene="ftsE"
                     /locus_tag="SLE65_001596"
     CDS             14270..14956
                     /gene="ftsE"
                     /locus_tag="SLE65_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEI8448892.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14940..15833
                     /locus_tag="SLE65_001597"
     CDS             14940..15833
                     /locus_tag="SLE65_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8448893.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            15985..17433
                     /gene="cls"
                     /locus_tag="SLE65_001598"
     CDS             15985..17433
                     /gene="cls"
                     /locus_tag="SLE65_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEI8448894.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEIAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYILQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            17770..18627
                     /locus_tag="SLE65_001599"
     CDS             17770..18627
                     /locus_tag="SLE65_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEI8448895.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18742..19662
                     /gene="pstC"
                     /locus_tag="SLE65_001600"
     CDS             18742..19662
                     /gene="pstC"
                     /locus_tag="SLE65_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEI8448896.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19662..20546
                     /gene="pstA"
                     /locus_tag="SLE65_001601"
     CDS             19662..20546
                     /gene="pstA"
                     /locus_tag="SLE65_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEI8448897.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20561..21367
                     /gene="pstB"
                     /locus_tag="SLE65_001602"
     CDS             20561..21367
                     /gene="pstB"
                     /locus_tag="SLE65_001602"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEI8448898.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            21383..22141
                     /locus_tag="SLE65_001603"
     CDS             21383..22141
                     /locus_tag="SLE65_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEI8448899.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            22154..22831
                     /gene="phoU"
                     /locus_tag="SLE65_001604"
     CDS             22154..22831
                     /gene="phoU"
                     /locus_tag="SLE65_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEI8448900.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            23068..24099
                     /locus_tag="SLE65_001605"
     CDS             23068..24099
                     /locus_tag="SLE65_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HEI8448901.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTNQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKHGLFALGSLIINIVLLLLLLLIFTKIEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNLWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            24096..24863
                     /locus_tag="SLE65_001606"
     CDS             24096..24863
                     /locus_tag="SLE65_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HEI8448902.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTTIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            24963..26531
                     /gene="liaX"
                     /locus_tag="SLE65_001607"
     CDS             24963..26531
                     /gene="liaX"
                     /locus_tag="SLE65_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HEI8448903.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            26828..27148
                     /locus_tag="SLE65_001608"
     CDS             26828..27148
                     /locus_tag="SLE65_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEI8448904.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            27148..27498
                     /locus_tag="SLE65_001609"
     CDS             27148..27498
                     /locus_tag="SLE65_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEI8448905.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            27665..28603
                     /locus_tag="SLE65_001610"
     CDS             27665..28603
                     /locus_tag="SLE65_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEI8448906.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            28618..29448
                     /locus_tag="SLE65_001611"
     CDS             28618..29448
                     /locus_tag="SLE65_001611"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEI8448907.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            29492..30517
                     /locus_tag="SLE65_001612"
     CDS             29492..30517
                     /locus_tag="SLE65_001612"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEI8448908.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHCLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPVEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            30532..31470
                     /gene="galU"
                     /locus_tag="SLE65_001613"
     CDS             30532..31470
                     /gene="galU"
                     /locus_tag="SLE65_001613"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEI8448909.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            31595..32035
                     /locus_tag="SLE65_001614"
     CDS             31595..32035
                     /locus_tag="SLE65_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEI8448910.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            32038..32640
                     /locus_tag="SLE65_001615"
     CDS             32038..32640
                     /locus_tag="SLE65_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEI8448911.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIIIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
BASE COUNT        10843 a         5540 c         7079 g         9200 t
ORIGIN      
        1 ttttgtctca gtcccttttt ttgcatattt ttagcattta tttcctaaaa aatgtaaggg
       61 gattcctata tttttaagta tacttgtttt tccttttata cattttatgg tattatcatt
      121 ttattagtta ttataaaaca atcgttagaa aggacgtcat tatgcaagta tacggaattg
      181 atgcggtgct tcgaatcgtg agtcatttgg cgtttatcta cttagccttc tggtctttac
      241 gttcgttacg cattgaaact tttttcagac caatgcataa tacgcaaatt agaatggcaa
      301 tcgtactttt ttcaattttt ttagggtaca ctgcaagtaa ttttttctta gaagttatcg
      361 ctttatgccg aaatcttttc gttagcctgt aaattttaaa aaaaggtact attttaaaag
      421 caaggatgtt ataatagaaa agattttgag taagtgtatg ctcattggaa ttttttggag
      481 ggaacaacat ggaagagatc atcgtaagag gtggcaatca attaaatgga acagtaagaa
      541 ttgaaggagc taaaaatgct gttttgccta ttttagctgc tagtttgtta gcagaagaag
      601 gtattacgac attagacaac gttccgattc tttctgatgt cttcactatg aatcaagtga
      661 ttcgtcactt aaacgtagat gtagattttg atgaacaaaa gaatcaagta acaatcgacg
      721 cttcaagaca attagaaatc gaagcgcctt atgagtatgt tagtcaaatg cgtgcttcaa
      781 tcgttgtgat gggtccgcta cttgccagaa atggacatgc aaaagtagct atgcctggtg
      841 gatgtgcgat tggtaaacga ccaatcgatt tgcatttaaa aggatttcaa gctttaggag
      901 caaaaattat tcaaaaaaac ggctatatcg aagcaattgc ggatgaattg atcggtaaca
      961 cgatttattt agatttccct agtgtaggtg ctactcaaaa tatcatgatg gctgccgtaa
     1021 aagcaaaagg aacaaccatc attgaaaacg tagctcgcga accagaaatc gttgatttag
     1081 caaacatttt gaataaaatg ggcgctcaag tctatggagc tggtactgaa acaatgcgta
     1141 ttgaaggcgt ggatcattta catgcagtca accactcaat cgtacaagat cgtatcgaag
     1201 caggtacctt tatggttgct gctgcaatga cacaaggcaa tgtgctgatt gcagatgcta
     1261 tctctgaaca taaccgccca ttgatttcta aattgatcga aatgggtgca gaaatcattg
     1321 aagaagaagg cggagtccgt gtcatcggac caaaacatat cttacctaca gatgtaaaaa
     1381 cgatgcctca tcctggtttc cctacagata tgcaagctca aatgacagct atccaattag
     1441 ttgcagaagg tacaagtgta gtgactgaaa cagtgtttga aaatcgtttc caacatttag
     1501 aagagatgcg ccgtatgaac gctcatgtca aaatcgacgg aaatgtagca atcatggatg
     1561 gaaaccatga attgcaaggt gcagaagtat atgcaacaga cttgcgggca gcagcagcat
     1621 tagttttagc tggcttgaaa gcaaatggaa tcacacgtgt gcgtaacttg aattatctag
     1681 accgtggata ttataatttc catatcaaac tacagcaatt aggtgcagac gttgaacgtg
     1741 tagacatgga tcaaacttct gctgaaaaaa cagcacaaac gattgcttaa ggaagtggct
     1801 gaatgagtaa ccaacgatat atcttattaa ctttgataaa gattttaatg gtgatcttat
     1861 tgcttatcct tctttttgtg gccggaacga tgatcggata tggtgtcatc ggtggcggca
     1921 atccatttaa agtatttcag ccaagtttgt ggattcatat tcgagacttt tttcattgat
     1981 aaataagaat cacagtggtt ctagtcgata tgaagtgagc catgaagcag aacatgataa
     2041 aagaaaacag aagggaacgt tgacgttagt cgcgatccct ttttttagta aaagaaaaga
     2101 aggaatctaa ttgatgaaga agatattgat ttatttagtt agaggatatc agcgctttat
     2161 ttcgcctgca tttccaccta gctgccgtta ttacccaacc tgttccaatt atatgataaa
     2221 agcaattcaa acccatggcg cgctaaaagg gacggtaatg gggactgcac ggatcttacg
     2281 ctgtcatcct tttgtcaaag gcggtatcga ttatgtacca ttgacattcc gattaacgcg
     2341 aaataagaaa gataaaaaag aaccagatta taaaaaggtt gtgaaaaata cgggtagcac
     2401 tgagcgataa agaaacaatt tggaaaatag cttcttatat tttgcaaaat tgtgagttat
     2461 tgccgaagtg ttggattttg aacaccgtca aaaaaaaggt tgtgaaaaat acggctagca
     2521 ctgagcgata aagaaaaaga ggaaatttat tgtcaaagta acaactccgc aactacttat
     2581 atgggggaca aaaaatgatc gaagaactaa acaagaaaga tttaccatgg tccttgttat
     2641 tagatgcaga tcctgataaa gaaaaagttc aagtatatgt ttccagaggg agtggctgga
     2701 tatggaaaga aaaagaaaaa acaataggtg tactgatcta tgtggcaagg gaaaaagaat
     2761 acgaaatcgt caatgtagca gtaaccccaa cgtatcaagg aaaggggatt ggcggaaaat
     2821 tacttgagac agcttttcag aagctttcac aactcgcttc cagtcaaact cagatcatca
     2881 tacgaaccgg cagtactagc agtgcggcgt tacatctcta tcaaaaaatg ggctatgtgg
     2941 agattggtcg agtcaaagac tattttatcc atcattactc tgagcccatt tttgaaaatg
     3001 gagatcaatt aagggatcaa gtgattttag caattcactt acctaaaaat agctttaact
     3061 aataaaattt caattcaaga aaatgctttc aaatgctaaa tagatacatt acaatagctt
     3121 tagcaaacaa aaaggagaat atttttatgg gaatattagt ttttgatttt ggtggatcgg
     3181 ctgtcaaata tggttgttgg gatggcaaag agattaaagg taagggacaa tttgcaacgc
     3241 ctgaatcttg ggaagaaatg aaagcgcaat tatttcaagt ttataaaaaa atactcgttt
     3301 cttttgaagt cgaaggaatt ggaatcagct ctcctggagt agtgaataat gagaaacagg
     3361 tgattgaggg aatcagtgcg attccttata ttcatggatt taatattttc cgagatttgg
     3421 aaactctgtt tcaacttcca gtaacgattg aaaatgacgc caactgtgcc ggaatggctg
     3481 aattttatga aggtgctgcc cgcgattatc aagatgttgc ttttgttgtg gcaggaactg
     3541 ggattggcgg ggcgttgttc acgaaaggac aaatcaataa aggggcacat ctttacggtg
     3601 gagaatttgg gttgatgttc ttaaatggcg ataagacatt cagtaaactt ggtacagcgg
     3661 tacagatggc ttggcgttat tgtgaacgca aaggtctcga taaaaatgct tataccggaa
     3721 aagatgtctt tgaattagca gaaactggag atgcaatagc aaaagaagaa gttgagagtt
     3781 tttatacgta tcttacaaag ggattattca gtattcaatt ttcgtttgat ccagaagtga
     3841 tcgtattagg cggcggggtt tctgcaaaag aagggctcat tgatgagatc aaaagccgaa
     3901 tgaagaagct gacagaacaa ttcgatctgc atgatttcga accgcagatt ttattatgtg
     3961 aatacagaaa cgatgctaat cttgtaggtg cagcagcaaa ctatctcgct gtacgtcaag
     4021 gggagaatta agagctttag agaaggtgca gcttgcataa aagaagtgaa tgaaatgaat
     4081 aggagatttt tacctaagga atgttttatt tgctgcagta tgataaaata tctgagaggt
     4141 gaaaatgatg tcaaaaaaaa ataaagatat tgaagtgcgt atagaagaag tgaaaaaaga
     4201 tatcaaaggt aagaattatg aagtcactca gttatttata gggaaaaaaa tgattggtga
     4261 gatcttagcc tatggaccaa aagaatatga aattttcttt ggtgaagaag attttggaaa
     4321 agaaaaaagt cttgaaaatg cgatagaaac agtgattcga cactggaatc tgcacgaata
     4381 aaaaaatatc aaaaaaactt tcaataaagg gttgcaaaaa tctggaaaat taggtattat
     4441 aactaagtca ggttgataca aacctttcgg aggagtagcg aagtggctaa acgcgacgga
     4501 ctgtaaatcc gttccttagg gttcagtggt tcgaatccac tctcctccat ttcattgggg
     4561 tatagccaag cggtaaggca agggactttg actccctcat gcgttggttc gaatccagct
     4621 accccagtat accacaatcg taagctctcg ttagttcgag agctcttttt tttgctttgc
     4681 taccttgttc cttgaagatt ctgctgattt aagatagagt taagttaact acaagaattg
     4741 gagggatcca catgaaatgg aaagaaaaag tagacgaagc agctgaaaag ttatatgatt
     4801 tggtcaaatc agaaaaatac aatattgaag tgaatattcc gaaaaaaggc ggaaaagcgg
     4861 tccgggtaaa atcaaaacgc ccaacgaatc atacaaaaaa atggatggct aaaaaccgct
     4921 aataataaca aaagatccat aagtcggcat tttcatcgat tttagggtct tttgttattt
     4981 tctaggttgg acatatctaa aaaattgttt ctgacaatag gagtaggaag aacgatgtgt
     5041 gtctaaatcc tctgttgatg gatagaaacc tttatctttt tcagttgtga atcaggtata
     5101 taccagttat aatagaagaa acgaaaggac gggtgtacgt tatgtcgaat caattacctg
     5161 tatatataca gattcatgac caattaaaaa atgaaatcga acaaggtata tggaaagtcg
     5221 gagaccgtct tccttcagaa agagaattag cagtgaaatt caatgtcagc cgtatgacgt
     5281 tgagacaagc aattcaaaac ttggcagatg aaggaatctt agaaagaaag atcggttcgg
     5341 gtacatatgt tgcacgagaa aaagtacaag aaaaaatgtc tggtgcaaca agttttacag
     5401 aaattatgga atcacaaaat cgagtaccgt ctagtcggac aatctcttat ttcttgactt
     5461 cgccaagctc aagtgaaatg gaaaaactaa acttgagtaa agatgacacg atcttgcgaa
     5521 tggaacgtat tcgtttcgca gatgatgtcc ctatttgttt tgaagttgcc agtgtgccac
     5581 aaaagctgat cgatggctac agcaaagcag agattactga atcgttgtat cgcacgctag
     5641 aagaaaaagg cgggaaaaag atcggtccag cgaatcaaac gattactgct gtgttggctt
     5701 ctgagaaaat tgctgactat ttagaggtaa aacgaggaga tgcagttctt cgtttgcgcc
     5761 agatttctta ttttgaagac ggtacgccgt ttgagtatgt gcgtacgcaa tacgtaggaa
     5821 atcgttttga gttttatttg gaaaaataaa aaacaggtga tccctgattc cgtattagaa
     5881 ataaaagaga atcagaatca cctgttttta tatatgatca gttaccagtt gctcgtgata
     5941 agaaacagga ccctcttcaa attggacttg tccgttcagc agctcaatga tggattcttt
     6001 aaagtggtca gcactttttt catctacagc acagatgacg ctaacttgat cagtatattg
     6061 gatttctttt ataaaaaaat gttggagttc aagataattc tgtaattttc ctagttgcgg
     6121 atacgtgatc atcacagaga tctcctgttg caaggtacct tctacgattc caatgtcaga
     6181 caatgcttga gagaccgcat gagtgtatgc tcgtattaat ccgcctgtgc cgagtttcgt
     6241 tcctccaaaa tatcgagtga ctactgcagc tacattgatc agttgatttt ttttgaggac
     6301 ttccaacatc ggtatgcccg ccgttccact tggttctcca tcatcgctgc ttcgctggat
     6361 ttcatttttt tctccaatga tgaaggcgct gcagttatgg ttcgctttcc aatgttcttt
     6421 ttttatttct tgaatgaaac tttttgcttc gtcctctgat tctattcgtc taagagaaca
     6481 gataaagcgt gattttttga tctcgatctc actttgtcca ttttctttta ttgtacgata
     6541 gcgctcgatc atcttgtcac ctcttttttc attttcttta ttcagtataa ataaagttct
     6601 aggttgtttc aacactgtaa cggttgcgca attgctgtag tatgcgataa taaagacaaa
     6661 ggcaggtgga tctggggatg caggaacgaa tgaaaaagta cgatgcaatt acgcattatt
     6721 tgaagaacaa tggcggctct caagtaacgt tgacctttac ccaatttgac gaactgctgt
     6781 ttcccagtaa cggacttccc aaaacagcaa gggaaagtac agattggtgg gcaaatgatt
     6841 ataaacaccc tgaaaaaggt gcctatggct ggataaatgc aggctatgaa gtagttgtca
     6901 tcaatttgga caaagaatat gtcgtgttca ataaattagt gaaatctagt tggctatttg
     6961 attaaataaa ccgcgtttag aaaacgttga caaatttctt tctttttata taatagagta
     7021 acagacgcga agaaaacgtt tgcgtagttt gttttaaaaa ggagagaaaa gtatggctaa
     7081 aaaaacaatc atgcttgtat gttcggctgg tatgagcaca agtttactag taacaaaaat
     7141 gcaaaaagct gctgaagcaa aaggaatcga ctctgatatt ttcgctgtgt ccgcttctga
     7201 cgcagataac aatcttgcaa ataaagacgt ggatgtgttg ttattaggcc cacaagttcg
     7261 ctttatgaaa gctgattttg agaaacgtct ggaaccaaaa ggcattcctt tagatgtcat
     7321 caatatggct gattatggta tgatgaatgg cgaaaaagtg ttagatcaag caatcacgct
     7381 cataggtgaa taaatagaac agtataacta tcgaacaagc gatccaaaaa atagatcgct
     7441 tgttttttcg tatatttttt tagggcgaat aatatgaatc atttttgggg tagaaggctt
     7501 ctgacgagag atattaaagc aatagactgt gaggaggtaa atttaccaaa ttatgagaag
     7561 atcgcagcag tggaacgttt gagcaactgg attctttgtc atcgctgtgg aatgagaacg
     7621 tccgtcattg atggacagct tgcagattac ggttattttt gtacacattg tctatattta
     7681 gggcgatgcg acactcaaca agatttatat ttgtttgatc agcctgaagc aaaacctcga
     7741 gaagtcgtct ttttttggac aggacagctt actgaaaaac aaacggaaat ctcaaagaga
     7801 atactttgcc attcagaaaa aagacatcat cttatttggg ctgtaacagg tgcagggaaa
     7861 acagagatgc tttatcctat tttagtggaa actttaaaag ctggaggaag agtagcgatt
     7921 tgtacaccgc gagtcgatgt ttgtaatgaa ttgtttttac gctatcgtta tgtttttcca
     7981 gaagaaaaaa tcacgttgct ccatgggaat acagcaacgg cttatacctt tacttctttt
     8041 gttatctgta cgattcatca gctataccgt ttttatcggt cctttgattt aatagtgatc
     8101 gatgagatcg atgcgtttcc ttataacggg gatgcaggat tagctcatgc tgtgcaaaca
     8161 gcgattaaac cagacggacg attcatctac ttaagtgcca cacctgataa aaagttacta
     8221 aaggagatca agcagacgtt tgacatccac aaacttgctt tacgctttca tcggcgtttg
     8281 cttcctgaac ccgtcttggt tttcatgaat aattggcgac aaaaatgcaa gaacaagaag
     8341 aagataaaat ctttggtgcg gatcattcat caattaatta aagaaaacca tatcctttta
     8401 ttttgtccaa gtatcacgat gatgcatcgt ttgaaagcca cacttcaaga ggctcttccg
     8461 agatatgaga tcacagatgt ttcttcaaga gacaatcagc gggcggaaaa agtccagaaa
     8521 atgcgagaag caaaatatga catactgtta accacgatga tccttgaacg tggagtcaca
     8581 tttgaaagaa tatccgttat cgttttagga gcggatcatc cggtttttac taaatcttct
     8641 ttggtacaaa tcgcaggaag agccgatcgt aaagggcctt atacgaacag tcaagtatat
     8701 tttttctatg aagaaaaaac tgcagctatt cgaaaagctt gtcaggaaat caaagaaatg
     8761 aatgaagaag ggaagaagat actgtgaggt gcagttgctg cagtaaagat atcgtccaaa
     8821 atttaacatt cagcgagatt attggtgttt cgaaatacag attacctcag acttgttcag
     8881 tttgtcgcgc acaatttcat ttattggaaa caagaggctg ttctggctgt caaaaaccaa
     8941 tccatttcaa tctagagagt acgaaaaaga aagtaaattc tatccccgtt tactgcagtg
     9001 actgtcaaga atggaagaag aaatatccga cctatgattt tcagcaccgt gccttttttg
     9061 tgtacgatga aaatatgaag gcctggctca atcaatacaa gtttatggga gatatccgac
     9121 tagcaggcac ctttgcatat aaatggacgc agataaaaaa agaatacccg acatacatct
     9181 attgtccaat acctttatct gaaaaaaggc gaacagaaag aggattcaat caagtaagcg
     9241 agatgttgaa agcagcaaga attccttttc agatgctact caaaagagag aagcatctgc
     9301 tggctcaagc aaaaaacacg cgaaaggaaa gattggagat gcctcaacct tttgaacttg
     9361 cagtcacctt ttctaagata caaaataaaa aaatattgat tattgatgat gtctatacaa
     9421 caggacagac tcttttccac gcagcagatt gtttgcagat cgcacagccg aaaatcatcc
     9481 gaactatttc tttggcgaga tgaattagat gtggaaattt gatagcgatt taatttgcaa
     9541 ataacctaga gttcgatata atagaattaa gaagagggaa agagtggtcc ttctccttct
     9601 tgattgtggt agacgaaagg ggtaattttt atgtttagat ataatgtacg cggcgaaaat
     9661 atcgaagtaa ctgaagcgat tcgcgactac gttgagaaaa aagtaggcaa actagaacgc
     9721 tatttcagtg acgcacccga tgcaacggcg catgtgaact taaaagttta tacagaaaaa
     9781 acagcaaaag tggaagtaac gatcccatta ccttatcttg tattacgtgc cgaagaaact
     9841 tctccagatt tatacgcaag tatcgatttg gttgttgaca aattggaacg ccaaatccgc
     9901 aaattcaaaa caaaaattaa tcgtaaatcc cgtgaaacgg gcatgaatac tgcaaatgct
     9961 gctgctttat tcaatgaaga ggacgaaaac gaaaatgatt ctgaattaga tatcgtacgt
    10021 acgaaacgcc tttcattgaa accaatggat agtgaagaag cagtcttgca aatgaacatg
    10081 ctgggacata acttctttat ttttgaagat gcagaaacaa atggtacaag tatcgtttac
    10141 cgccgtaaag atggaaaata cggactgatt gaaacagact gatcagcctt acttaaataa
    10201 caacgaaaac ttgcagcagc tactgacagc tgccgcaagt ttttttgagt ttcctcctct
    10261 tttagatgaa atatgaataa attatgaagt tcttacttta atacgcttaa gatatttcaa
    10321 ttatctataa ctaatgataa aatgaaaagt aaagtctaca tagtctggat aatacacaga
    10381 aggaaaagga gattacacaa cgcatggcca atttgattcg ttcacttatc gaaaacgata
    10441 agaaagaact aaaacgttta gatagcattg caaaaaaagt tgaagcatac gctgaccaaa
    10501 tggcagcatt aactgatgaa caattacagg caaaaactgc tgaattcaag ggcagatacc
    10561 aaaaaggaga aacattagat caattacttc cggaagcttt tgcagtcgtc cgagaagcag
    10621 caaaacgtgt attaggttta tatccatacc acgtacaatt gatgggtgga atcgtgcttc
    10681 acgatggaaa tatccctgaa atgcgtactg gtgaaggtaa aaccttgacc gcaacgatgc
    10741 cagtatatct aaatgctctg actggcgaag gggtacacgt agttaccgtc aatgaatatt
    10801 tagcaacccg tgactcgacg gaaatgggcg aactttataa tttcttagga ttaacagtgg
    10861 ggttgaatat caactcaaaa tcttcggatg aaaaacgcga ggcttataat tgtgatatca
    10921 cttatagtac gaataatgaa ttaggatttg actacttgag agacaatatg gtcgtttacc
    10981 gccatcaaat ggtacaacgt ccgctgaatt atgccattgt cgatgaagtt gactcaatct
    11041 tgattgatga agcgagaacg ccgctgatca tttcagggca agcagaaaaa tccacagctt
    11101 tatatacaag agcagacaac ttcgtgaaac gtttgaaaga agaagaagat tataaaatcg
    11161 atgtacaatc aaaaacaatc agtttaaccg aagcagggat cgaaaaagca gaagaaacat
    11221 tcggtttgga taacttatac gacattgaaa atactgcatt gacccatcac ttggatcaag
    11281 cattgagagc caactatatc atgcttttag atatcgatta tgttgtccaa gacggaaaag
    11341 tactgattgt tgaccagttc actggtcgga tcatggatgg acgccgttat tcagatggac
    11401 ttcaccaagc aatcgaagct aaagaaggcg tagagatcga agacgaaacg aaaaccatgg
    11461 cgacgatcac tttccagaac tatttccgta tgtacaagaa acttgcggga atgactggta
    11521 cagctaaaac agaagaagaa gaattcagag aaatttataa catccaagta taccagattc
    11581 cgacaaatcg tccggttatc cgtgatgatc gtccagattt gctttaccca acattacaaa
    11641 gcaagttcca cgctgtcgtg caagatatca aagatcgcta ccgcaaaggt caacctgtgt
    11701 tagtcggaac tgttgcggtt gaaacatctg agttattatc agatatgctg aatcaagaac
    11761 gtattcctca tgaagtgctg aatgcgaaaa atcactttaa agaagcagag atcatcatga
    11821 atgctggtca aaaaggtgct gtgacgattg ctaccaacat ggctggtcgg ggaacagata
    11881 tcaagttagg acttggggta agagaacttg gtggtctagc agttatcggg acagaacgac
    11941 atgaatctcg tcgtatcgat aaccagcttc gaggacgtgc aggacgtcaa ggagaccctg
    12001 gtatgtcaca gttctacttg tcattggaag atgatttgat gaaacgattc ggttcagaac
    12061 gaatcaaagc tttcttagat cggatgaaga tcggtgagga agatgctgtt atccaaagca
    12121 agatgctgac gaaacaagta gaatctgcac aaaaacgtgt agaaggaaat aactatgaca
    12181 cacgtaaaaa cgtcttacaa tacgatgatg tgatgcgtga acaacgtgaa gtaatctata
    12241 aacagcgaca agaagtaatc atggaagaaa aaagcttatc caagccacta atgaacatgg
    12301 tcaaacggac aatcagtcgt gtagtagatg cgcatacaca attagagaaa gaaaactgga
    12361 atttggaaag tatcatcgat tttgccggca gtactcttgt ccatgaagat agtattactc
    12421 ttgcagatat cgaaggaaaa acagctcagg agatcaaaga gtatctaaac gaacgagcac
    12481 aagaagtatt taataccaaa gcggctcaac taaatggtcc agagcaactg ttggaatttg
    12541 aaaaagtcgt gatcttgcgt gttgtggact ctaaatggac agaccatatt gacgcaatgg
    12601 atcaattacg tcagtcaatc ggcttacgtg cttatggaca gaacaatcca ttagtcgaat
    12661 atcaaacaga aggctataag atgtttgaag atatggtagg cgccatcgag tatgaagtca
    12721 ctcgaatctt tatgaaagct gagatccgtc aaaacgtaca gcgtgaacag gtttctcaag
    12781 gaacagcttc tcactcagaa gacggagatg ccaaagaaaa tagtaatact agcgcgaaaa
    12841 aacagccaat ccatgtgaac aaggtcggaa gaaatgatcc ttgtccttgt ggaagcggga
    12901 aaaaatataa gaactgtcat ggaaaaaatg caaactaatt tctgacagca ggattggtga
    12961 gacaaattct ttttttaaga attcgtctca ccttctttct gttatttgct gattctgtta
    13021 gactagatat aatgaaaaaa gtatagtgaa agaaggaaaa aacatggaaa tatccgaaat
    13081 tcgaaatctc ctgacagaaa tgcaggaaaa ggtcacaagt ttcaggaggt ctctttgact
    13141 tagatcagct ggaagaagac atcgcggaag cagaagcaaa aatggctgaa cctggttttt
    13201 gggatgacag cgaagccgca caaaaagtga tcagtgaaaa taacgctaat aaagaaacct
    13261 atgaccaatt ccattctctt gccgaagaac tagaagaaat cgaattgatg gtggagatgc
    13321 tgcaagaaga acctgatgca gcaatgcaag aagaagcaga aacacgtatc aatgcattag
    13381 atgaaaaaat gaagacgtat gaattatcta tgctgttaga cggaccttat gatcgaaaca
    13441 atgcgatcgt cgaattgcat ccaggggctg gcggaacgga gtcccaagac tggggcagca
    13501 tgcttttacg tatgtataca cgttgggcag agcagcatgg ctatcaagta gaaacactag
    13561 attatcaagc aggtgatgaa gcagggatca agagtgtgac cctgctgatt aaaggacata
    13621 acgcttttgg ttatctaaaa tcagaaaaag gtgttcatcg ccttgtacgg atttcgcctt
    13681 ttgactcagc gaaacgacgt catacttctt tttgttcggt agatgtgatg ccagagcttg
    13741 atgaaacgat cgatatagaa atcaatccag atgatttgaa aatcgatacg taccgagcaa
    13801 gtggtgcagg tggtcagcac atcaataaaa cagaatctgc tgtacggatc actcacttgc
    13861 ctacaggaac agtagtagct agtcaggcac aacgctcaca attgaaaaac cgtgagcaag
    13921 cgatggggat gttaaaagct aagctttatc aattagaagt ggaaaagaaa gaacaagaag
    13981 cagctgcact tcgaggagaa caaaaagaaa tcggctgggg ttcacagatc cgttcttatg
    14041 ttttccatcc ctattctatg gtaaaagacc atcggacaaa cgtagagaca ggaaatgtcc
    14101 aagcagttat ggacggtgac cttgatttat ttattgacgg ctatttaaaa atgcatctac
    14161 aataagaacc cattgttaaa ttgaaataaa attgtaagat tttgcaagca tgttgaaaca
    14221 ttgccatgct ataatagcta aagactgaaa aagatatgga gagaacgcca tgattgaaat
    14281 gaaggatgta atgaagaagt actcaaatgg tacgaccgct atccgcaatc tctcgattgt
    14341 catcgaacaa ggagagtttg tctatgtggt tggtccgtct ggagccggta aatctacatt
    14401 catcaaattg atgtatcgag aagaaaaagc ttcaaaagga actttgaacg tcgcaggtca
    14461 tgatctaata gcaatcaaaa accgcgaagt tccttatcta cgcagagaaa tcggcgtggt
    14521 gttccaagac tataaattat taccaagaaa aacagtatat gaaaatgttg cgtacgctat
    14581 gcaagttatc ggcagaaaac ctcgagatat caaaaaacga gtaatggaag tgctggacct
    14641 tgttggtttg aaacacaaag ttcgagtctt tcctagcgaa ttatccggtg gggaacagca
    14701 acgtgtctct attgctcggg caatcgtgaa tacgcctaaa gtacttatcg cggatgaacc
    14761 gacaggaaat ctggatccag aaaactcatg ggaaatcatg aaattattag atcggatcaa
    14821 tgcccaagga actactgtcg tgatggctac acataacagt acgatcgtaa atacgattcg
    14881 gcaccgagta attgctatcg aaaacggccg cattattcga gatcaagcgg aaggggaata
    14941 tggatacgat gattagaacc tttttccgcc atttattaga aagtatcaag agtttgaaac
    15001 gtaacggctg gatgacagtt gcttcagtca gtgcggtaac gatcacgttg actttagtcg
    15061 gtgtattcat ggcagttatc atgaatgcaa ctaaattagc tcaggatata gaaggaaacg
    15121 ttgatgtatc tgtattcgta gatatcggta caaaagacga agagatgaaa aagctagaaa
    15181 aagaattgaa tgacttagat catgttaaaa aagttgaatt ttcaagtaaa gaacaggaat
    15241 tgaaaaaaat ccaaaacgaa atgggtgatt cctggaaatt gtttgaaggt gacaataacc
    15301 cgttatatga tgtgtatgta gtaagtgcta ctgatccttc ttatacaaaa caagtagcag
    15361 aagaagcagc agatttgaag aatgtttctc gttctgatta cggtggagct tcctcagatc
    15421 ggattttcca aatcgctggt gcagttcgga catggggatt agttgcagcg gcattgctgc
    15481 tgttcgtagc gatgtttctc atttcgaaca cgattcggat cacgattttg tctagacagc
    15541 gtgaaattca aatcatgcgt ttagtcggtg caaaaaatgg atatattcgc tggccgtttt
    15601 tccttgaagg tggctggatc ggtctgatcg gtgcgattct tccgattttg atcatcacat
    15661 ttggttatgc atggtttttc caattgatca atccatcatt attacgttcc cattattcat
    15721 tgattcatcc acaaaatatc gtttggaaaa tcaatctttt aatggtcggc attggtgtga
    15781 tcattggttc acttggctcg atcatttcta tgagacgttt cttgaaattc taataccaca
    15841 atataaataa aatgagaaag ttggacagtt tcgttccagc tttctttttt tattggctag
    15901 gagaatagaa ggaagcggct tttttccctt tactttaaaa aacaacttgg gtattcttaa
    15961 gttggtagag gaagaggtga agccgtgaaa attatcgttg acaatttttt tacgatcctt
    16021 ttgattatga atattttgct ttcctttatc atcgtttttc gagaaagaaa ggaaactgct
    16081 caaacatggg catggctgct cgttttgatg ttcattccag ttgtaggatt tattttatat
    16141 atttttttag gaagagggat ttccaaagag aaaatctttg atttgaagat ccaagggaaa
    16201 atcggtaaga acctggaaat tgaagaagac aaacaggcat tgatgcgagg gctttatcct
    16261 catccgccta ctggacaagt agatgtgaaa caattgatct atatgctcac ggtatttgaa
    16321 agtacgctct atacgactaa aaatgaaatc actttattta cagatggtcg tgaaaaattc
    16381 gatgcgctga ttgaagatat caagcaagca gaagaccata tccacttcca gtattatatt
    16441 tatcgcagtg atgcattagg tgaagaagtt cgagatgcat tgacagaggc ggcaagacga
    16501 ggggtaaaag tcagagtcct tcttgatgca tggggttcca cacaagtttc ttccagcttt
    16561 tttcagaatt tgaaaaaagc aggcggagaa atcgcatttt tctttcctct atttgttccg
    16621 tatattaatc ctcggatcaa ttatcgcaat catcgtaaaa tcgtagttat tgatgggaaa
    16681 atcggatata caggtgggtt caatgttgga aatgaatatc taggattggt aaagaaattt
    16741 ggttattggc gagacaatca tttgcgtatt tacggagaag cggtgtatat cttgcaaaac
    16801 cgttttttga tggactggaa ttctcagcat acaaaagaag taggctattc tcccaaattt
    16861 tttccgtcca ttcactctac tggtgatata gctgttcaaa tcgtgacaag cggaccagat
    16921 accgaacatg aacaaatcaa aatgacttat ttgaaaatga tttcgttagc caaacgggag
    16981 atattgatcc aaacgcctta ttacataccg gatggatcga ttcatgaagc actgaagttg
    17041 gctcttcttt caggcgtaaa agttcatatc caaataccta acaaaccaga tcatcttctc
    17101 gtttactggg caacgtattc tttcgctgca gagctgatcg agtatggagc aaggatcgaa
    17161 acatatgaga atggatttat tcatgcaaag acgatgatta tcgatggtgg cattgtttca
    17221 gttggctcag caaatatcga tgttcgttca tttcgcttgg actttgaggt caatacactg
    17281 atttatgatg aacgaatggc ttcacgtgta agaaaagcat tttttgaaga ctcgaaaatt
    17341 tctacgcatc tcacaaaaga aatgtatgaa aaccgaggaa taatcatcaa gatgaaagaa
    17401 ggattagcaa gattgatttc gccgctcctt taaaacacaa aaaggacatg agaaccatca
    17461 acagatggag atctcgtgtc cttttctaac ggggccattt ctgagagtac gtcagaaatg
    17521 gagaaagcgt ctcgcatgag cgaaattaac tttggggtat ctcttgtttt ttggggaaag
    17581 caagaaataa gctaatatat gctattaaaa gagacacatt tcaaagccag tatagcatag
    17641 aaacttttaa tgagatagtt ttttttacaa ttatgaggat ttattttgtt atttaatgat
    17701 tttgattcgt tttcatcaag taatgaaaat gataaaataa acatacttta ggattaaagg
    17761 agatttctaa tgaaaaaact taaattattc ttaccaataa taggattagc tattctttta
    17821 tcaggctgtt caaagtggat tgatcgagga gaatccatta cggctgttgg ctcttctgct
    17881 ttacagcctt tagtagaaac agttgctgaa acttaccaga cagaaaatcc tggaaaattc
    17941 atcaatgtac aagggggcgg aagcggaact ggtttgtctc aagtacagtc aggagcagtc
    18001 gacatcggaa actctgattt gtttgcggaa gaaaaatcgg ggatcgatgc ctcagcatta
    18061 gtcgatcatc gagtagcagt tgttgggatc actcctattg tgaacaagga tattggcgta
    18121 aaagacatca gtatggaaaa cctgaaaaaa ctatttacag gcgagatcaa aaactggagt
    18181 gaagtcggtg gaaaagatca gccagtagtt atattgaacc gtgcttcagg aagcggaacc
    18241 cgtagcacgt ttgaaaaatg ggtattggac ggagaaacag ctgttcaggc acaagaacaa
    18301 gattcaagcg gaatggtgcg ccagatcgtt gccgacacac ccggtgcaat cagctatgtt
    18361 gctttttctt atgtttccga tgatgtagat acgttgaatg ttaacggtgt agaaccgaca
    18421 gatgaaaatg tgacaacgaa caaatggacg atttgggcat atgagcatat gtacacaaga
    18481 gatcatccaa aaaaactgac aaaagaattt ttagactata tcttatctga tgaagtacaa
    18541 gataacatcg ttggagaact aggttatatc cctgtttctc atatgaaagt cgaacgtgat
    18601 tggcaaggaa atatcgttaa agagtaatct ttacacaaaa tttacaaact tagctaaact
    18661 tttacatgtt attaaaacca aattgatgtt caatttgtac actgagtgag tatgttaaac
    18721 ctgattaagg gggagtcatc tgtggaagat gtgaaaaaag tattattaac aaaatcaaaa
    18781 cgttcaaaaa tggaacagcg tggaaaattc atcagttttt tatgtatcgc gctgatcgtg
    18841 ttggttgtat tatctatttt ttattttgta gctagtaaag gattggccac cttttttact
    18901 gataagatca atgtatttga ttttctgttt ggtacagatt ggaatccaag ccaaatcgga
    18961 gcaaatggga aaccaatggt aggggcattg cctatgatca caggttcgtt tattgtgacc
    19021 tttttatctg ctattgttgc cacaccattt gccattggtg cagcagtatt catgacggag
    19081 atctctccta aaaacggaac gaagatctta cagccggtca tcgagctgct tgtaggtatt
    19141 ccttctgtcg tttatggttt tatcggttta tcagttatcg tgccttttgt cagaagtatt
    19201 tttggcggga cagggtttgg tatcttagct ggtacatttg tgttgttcgt tatgatcttg
    19261 ccgactgtca caacgatgac tgttgatgca ttaaaggcag taccacggca ctatcgggaa
    19321 gcttcattag cgcttggtgc cacaagatgg caaacaatct acaaagtcgt gctacgagca
    19381 gccgtgcccg ggattttaac agcagtcgtt tttggtatgg ctcgtgcgtt tggtgaagcc
    19441 ttagctatcc aaatggtcat cggtaatgca gcattgatgc caacaggact tactactcct
    19501 gcttctacat tgacgtccat cttaacaatg ggaatcggaa atacaatcat gggaacagtt
    19561 gaaaataatg tgttatggtc attagcgctg atcttgctat tgatgtcatt attctttaat
    19621 atcgtgatcc gtatgattgg gaagaaagga gagctgaaat aatgaacgca aaacgctcag
    19681 ataaaattgc tacaggtgtt ttatatgtag tttcggggat catcgtattg attttagcag
    19741 ctttactact ttatatctta gttcggggaa taccgcacat ttcatggtcc ttcttgaccg
    19801 aaccttccaa agcctaccaa gaaggcggtg gaatcgggat ccagctattt aactcgattt
    19861 atttgctttt gatcacgatg atcatcagtt ttcctatttc tttaggtgcg ggtatctatc
    19921 tttcagaata tgctggaaaa aactggctga cagatgtgat tcgcacgtcg attgaaatct
    19981 tgagctcatt gccttctgtc gttgtcggtt tattcggttt cttggttttc gttattcaat
    20041 tccagtatgg tttctcgatt atttctggtg cattggcttt gactgtattc aacttgcctc
    20101 ttttgactag aacagttgag gagtctttac aagcggtcca ttacacacaa cgagaagcag
    20161 gattggcttt aggtttgtca cgctgggaaa cagtgataaa agtggtggtt ccagaagcga
    20221 caccagggat tttgactggt gtgatcctaa gttctggaag aatttttggt gaagcagctg
    20281 cattgatcta tacggctgga caaagtgcac ctgcgttaga ttttacgaac tggaatccat
    20341 taagtgtttc aagcccgatc agcattttcc gtcaagctga aacattagct gtccatattt
    20401 ggaagatcaa tacagaaggc acgatgcctg atggtgtttc tgtttcggct ggcgcttctg
    20461 cagtgttgat cattgctgtt ttactgttca acttcggcgc tcgtgcgatt ggcaaacgat
    20521 tataccgaaa aatgacttca gcctaaggag aagaagcaaa atgaaaaaat ataactggaa
    20581 tgaaacaaat gtcatcacca tgccaaaaga gaaagaagta gcactatata cggatgatct
    20641 acatgtctgg tatggcgaca atgaagcaat caaaggagtg gatctggaat ttgaaaaaaa
    20701 taagatcact gcactgattg gtccttccgg ctgcggaaaa tctacgtatc ttcgttcgtt
    20761 gaatcgaatg aatgatggga tcgctaatac gaaaatcact gggaaaatca tgtatcaagg
    20821 cgtagatatt aatgcgcctc aagtggatgt ttatgagatg cgcaaacgga ttggcatggt
    20881 ttttcaacgt cctaatccgt tcagcaagtc gatttatgac aatattacat ttgctttgaa
    20941 acagcacggc gaaaaaaaca aaaagaaatt agatgaaatc gttgaaacaa gcttgaaaca
    21001 agctgccttg tgggaccaag taaaagacag cttggacaaa agtgccttgg ctttatctgg
    21061 cgggcaacag caacgtttat gtattgctcg tgcgatcgcg atgaaacctg atatcttgct
    21121 gctagacgag ccggcaagtg ctttggaccc tatttcgaca ggaacggttg aagaaacact
    21181 tgtaaacttg aaagaagact atacgatcat catcgtgacg cataacatgc aacaagcggc
    21241 tcgtatcagc gactatactg cctttttcta tctaggaaaa gtaatggaat atgacaaaac
    21301 taacaagata tttaccagac caaaaattca ggcaaccgaa gattatgtgt ccggtcattt
    21361 tggttaagac ggaggcctca acatgacaaa agaaattatt tcatctaaag atcttcatct
    21421 gtattatgga aagaaagaag cactaaaagg gatcgatcta agtttcaatc aaggggaaat
    21481 cactgcgatg atcggtcctt ctggttgcgg gaaatccact tatctgcgtt ctttgaaccg
    21541 gatgaatgac ctgattccga atgtaacgat caccgggagt gttttatata aagacaaaga
    21601 catctatggt ccaaaaacag atgttgttga actaagaaaa gaaatcggca tggtattcca
    21661 gcagccaaac ccatttcctt tttctatcta tgaaaatgtc atctatggat tgaaattaaa
    21721 aggggaaaaa gataaaaaag tccttgatca agtagttgaa gaaagcctga aggcagcgtc
    21781 tgtttgggat gatgtgaaag acaaattgca taaaagtgct ttatctttat ccggtgggca
    21841 gcagcagcgt gtatgtatcg cacgtgtttt ggcagttaat ccggaaatca tcttattgga
    21901 tgaaccaaca agtgcgcttg atcctgtttc tactgggaaa atcgaaagta tgctgttaga
    21961 attaagagag cggtatacga tgatcatcgt gacccataat atgtctcaag cttcacgtat
    22021 ttcagataag acggcattct ttttagatgg tcacttgatc gaatacaatg atacgaagaa
    22081 gatattcatg aatccagaaa aacaagagac agaagattat atttcaggtc gatttggata
    22141 aggaggaaac ggaatgctac gtacacaatt tgaagaagaa ttgctgaatc tccataatca
    22201 gttctacgaa atggggatga tggtgagcag cgccgtgcac aagtcagttc gtgcatacat
    22261 caaacacgat aaaatcttag cccaagaagt tatcgaaaac gatataaata tcaataacat
    22321 ggaaacacgc ttggagaaga aaagttttga aatgatcgca ttgcaacagc cagttacaac
    22381 tgatttgcgt atgatcatta cggtcatgaa agctagctcg gatttagaac gtatggccga
    22441 tcatgcggtg tctgttgcta aatccacgat tcgcgtaaaa gggcagacga gaataccgga
    22501 aatcgaaaaa gagatctccg atatgtccga ttatgtgaaa aaaatggtgg acaacgtcct
    22561 agttgcttat gtcaaaacag acgaaaaaga cgcacgtacg atcgccaata tggatcaaag
    22621 agtcaatgac tatttcaatc gaatctataa tgcaacaatc aaaaatatgc aggaaaatcc
    22681 tgagacagtc atcagtggaa cagactactt gaatgttgcc agttatctag aacggatcgg
    22741 agactatgtg acaaacatct gtgaatggat cgtctacttg gctacaggga aaatcactga
    22801 gttaaatacg aaccacaatg agattttcta aactaaagcg gtgattctgc cgtttgttta
    22861 ggaaaagagg ttgtgaaatc agcggttgtg aaaaagctgt tctgcatcaa gtaataagaa
    22921 cagtcaaaca aaaatagctc ctcatatttt tcatttggct ggacttatta ccgcagatgc
    22981 aagcttttga acactgttta ttcgggaaag ggtttgtgac aaaatatgtc acaaaccctt
    23041 ttcatcattt catagaaagg ataaagaatg caaaaaaaaa ttagcatcat cactatattt
    23101 tttatttgtg tgcttacttc atgggttatt cagcatcaag ctgctttata tgaagtacct
    23161 gtcatcgaga tcgaaaaagt acgaataaaa gaggatcatc aattgattac aggaagactg
    23221 atgaacacga atcaaaaagg agaatcgatt tatttatcgg ttccttatca aaaaaatcaa
    23281 atagaaacag caaatataaa agcgagacaa atgtatctag tccaaatgca tggagatgaa
    23341 tggcagctag tagcaaaaaa aaatgatggc tggcttttct tcttcacaag tatcttcatt
    23401 ggcgccatgt tgcttattgg cggaaaacat ggtctatttg ctttaggaag tctcatcatc
    23461 aatatcgttt tacttttact tttgttgctc atctttacta aaatagaagg gatttctcta
    23521 ttaaatatat ctatcctgtt cgtcgttata gggatgatta ttagcatatt ggctttagat
    23581 ggatggaata gaagcagtat aatcaaaatt tcagctgcag ttacgagtgt ttttttagca
    23641 ttttttattt gtcttttgac aatgaatctt tggaaagacc aaggactgcg ctatgaggaa
    23701 ctgaattatc tgacacgacc gtatcgttct gtttttcttt ctagcgtact gattggaaca
    23761 gctggaggaa cactcgatac cgttatcaca gtcattgcga cattagaaga attgactaag
    23821 cgacaaccag aaataacagc gaaacagtta tggctttcgg gaaggcaagt gggtcgagat
    23881 gtgattggct cgatgaccaa tatccttttg ttcgtctata tcagtgggtc agttccatcg
    23941 cttcttttat atttaggaaa tcaatggtcg ttcaaagaaa cgatagaaca gcatttatca
    24001 ttggaatttt tacgcgtcat tgctggcagc ttaggaatag tattatcgat ccctatctcg
    24061 gtcctctttt ttctgactgt aaggaggctg aaacgatgaa tgtacttatt atacttgttg
    24121 ggattttagc aatcagcgtg ctacttattg gcggtacgca aggtatgtat attcttttag
    24181 gcttattcat caatttaggg atctttttct tgttgttatt cggttatcat cagaagtggc
    24241 cgatactggc attgtcggtc ataggatttt tattgattgc tgtggttatc ttatttttta
    24301 tcaacggtta taatctaaaa atgcgtgcag cttttgtgag tatactgatc tttttatttt
    24361 gtttcctact attgcttcct atcactgatt ttttagcaat ccaaggtttt acaacgatag
    24421 aactagaaga attatctggc ttagataaga ctttagcgat tgattttaga ttacttacga
    24481 gatcgttgct tctgattagt cttagtggtg ctgttttaga tgcgagtgta gcaatttcta
    24541 gtgggacatt cgaagtatat caggcaaatc cgcaattatc tttttaccaa ttgcgccatt
    24601 ctagtttcgc tattgctaaa aaaatattgg cgtcaacagt aatgacactt ctttttgcat
    24661 tcatgggaag ttctttagcg ttgatcctct ggtttattga tttagacatt ccttttcagc
    24721 aagtgatcaa tgaaaaatca tttgttctag aatatacgat ggctattctt accacattgt
    24781 ccgcactact tgttcttcct ttaacctgcg tgactacagc atatctcttt acaaaaaaga
    24841 aagaacaact caagatggag taaaagttac aacttaagtc ctatgacatt tttactgaat
    24901 cagtgcataa tatggatgta aggaaaagct tgcaaacaat tttgcttaag gaggcaattt
    24961 ccatgaaaga aagagaacgt attttagatt tagtgaaaaa aggaatcctt tcgactgaag
    25021 aaggcttaga tttattagaa agcatggcaa ctgaaaaaga cgaaaagcaa atcaaaaaag
    25081 aagcagacaa ggtaactgct agtcataaag aaaaagatca ggcaagtcaa ttgatcgata
    25141 aacttgaaaa cggcgaagaa gaaatttctg agccagttga tccaaaggaa agagaaagac
    25201 aagatcaaga aaacttagaa aagatcttag atgaactagc aactgaagcg aataaaactt
    25261 cggcgcgtct agatgaagta aatgctcaat tcgctgacaa taaggcagca cgcaatgaga
    25321 aacaggaagc attgatgcag ctgaatacaa aagaagaatt aggcgagttg acagaagaag
    25381 aattagcaca gcgtcagacg ttagaagcag aaatcaaaga gttagaagct agtggcgata
    25441 cactgttaga agaacaattg aaattagaag cagaattaaa agatatccgt aagaatcaat
    25501 ggtctgagaa aaaagaaacg tttactgata agtttgaatt gccagatgat tggaaagatc
    25561 aagcaacaga tacactgaat caagtaggcg aaaaaatgtc agaagctgga tcacagttag
    25621 gaaaattctt gaagaaaaca ttccaaactg tttcagaaac agtgaatgac aacatggaat
    25681 ggaaagatgt cagcttgcgt gtccctggga ttgcgacaac gaaatttgag catgaatttt
    25741 actatgaagc tcctgcagca agtatccttg atatcaaggc agcaaacgga aacgtgacgt
    25801 taaaaacgtg ggacagcaac gatgtgaaag ttgaagctaa gatcaaactt tacggaaaaa
    25861 tgggtgctga accatttgaa gcattctctg aacggagcca gattgaggtt aatgaagatc
    25921 atatctcctt ccaaattcca aataaacgtg tgcgtgcaga ccttgttttc tacttaccta
    25981 aacgagtata cgaccacgca gctattaaac ttctaaatgg caacatcatg attgaaacat
    26041 tggaagctaa agatatttat acaaaatcta cgaatggtaa catcatcgtg gaccaattaa
    26101 ctgcaacgat gctggaagta gaaggtgtaa acggcaatat cgatattcga aacgggaaca
    26161 tcttagattc tattatcgaa acagtaaatg gtacagtgac atttggtgcg acagcagaaa
    26221 acctttctgt gtctttggta aatggtgatg tacgtcttac gattaaagaa gataatttga
    26281 aaaaagtaga agcaagttca gtgaacggaa atgtcaaagt cgctttacca gatggcatcg
    26341 gtttggaagg acatgctaaa acaagtcttg gaagtatcaa cagccgtctg tccaattacg
    26401 aagtagttcg tgagaaaaaa gaacggacaa accaaatgtt gcaattccgt cgtgtttcag
    26461 atggtgaaat cgcgcaagtg caactttcaa cgacaacagg aagtatctat ttaaaagata
    26521 cagataaata aagaggttgt gaaagagatg ttcagccttg agcaataaga agcgattttg
    26581 taaaatagct tcccctattt tacaaaattg tgccttattg ccgataggct atctcttgaa
    26641 caccgtttac caagagatta tgaacttgcc aattatcgcc gagtcacaag gaataatttc
    26701 aaaaaaagct cgtcacgttt tatgaatatg gtaatttgtg accgagaatt ttgcaaaaag
    26761 acaccgatta agaagaaggt tgtcacaacg attttcttca tttaaaatag tagaacagag
    26821 gtgagacatg atgaaaaaaa agttgacaaa atccaataaa aatgttgttt tgacagggac
    26881 tttagcagga ataggagaat acatcgggat tgatccgact gttatccgtg tgctttatgt
    26941 attcctgagc ttagttgctt ttggaagtcc aatcatttta tacattttat tagctttgat
    27001 tatcccatct gcgcgttctg cacgaacaaa ctatggacat aacaatgcat attatgaaaa
    27061 aaacaattat cgtgaacaaa ctcgtgaaca aacaaaaaaa cgcaaagaag cggaaaaaat
    27121 cgatgatgac gaatggagtg acttttaatg tcgtactttc aacgtatttt agttaatacg
    27181 ttaacattca tatcattggc tgttcttttt cctgcgatgg tccatgtgag cagtatttgg
    27241 acggccgttc ttgccagctt cgtattgtct gtgttgaata tgtttgtcaa accgattttg
    27301 acgatactgt ccctgccctt tacattagtc acattgggat tgtttacgtt tgttatcaat
    27361 gcagcgattc ttaaaatgac ctcctttttt gtgggagcag aacattttag tttttcttca
    27421 ttcggtgcag cgttgttagt agctatcttg atgtcgcttg tcaatgtaat tgtcagcgaa
    27481 cataacagta gaaaataaaa gaaagctgtg ccgaactatc ggcgcagttt ttttatttag
    27541 aatcaggaat gcgttttcta ttacattggt aattaaataa aaacgttttt tttaattggt
    27601 agtacttttg gctagacaat gataaaatga tagagaacac tctaatagaa atgaggtagc
    27661 atgaatgtca gaagttgtaa aagttagcca attagtgaaa aaattatctt tggaaatcgt
    27721 gacaggcgac gagaaaagct tagaccgtgt catcgtaact ggggacatct cacgcccagg
    27781 actagagttg actggttatt ttaattatta ttcccataat cgtttacagc tatttggcag
    27841 taaagaaatc agttttgcgg aacggatgat cccagaagag cgtttgatca tcatgagaag
    27901 attatgtagt gaagatatgc ccgcatttat tatttcaaga ggattaccag ctccagaaga
    27961 aatgatccag gcagcaaatg aaaatgggat agctgtactg cgttctccca tctcaacttc
    28021 tcgcttatta ggagaattat ccagttattt agatggtcgc cttgcccctc gaacaagtgt
    28081 ccacggtgtt ttagtggatg tttacggatt aggtgtactg attcaaggtg acagtgggat
    28141 aggaaaaagt gaaacagcgt tggagttgat caaacgcggt catcgattga tcgcagacga
    28201 tcgagtagat gtttatcagc aagatgaatt aacggtgatc ggagaaccgc ctaaaatcct
    28261 ggaacatctg attgaaatcc gaggaatcgg gatcattgat gtaatgaatc tttttggtgc
    28321 gagtgcggta cgtggctcta tgcaagtcca gttggctgtt tatctggaag catgggcaaa
    28381 agataagaaa tacgaccgtc tgggctctga agacacgacc gttgaaatcg cggaagtagg
    28441 cattccacaa ataaaaatcc ctgtcaaaac aggacgaaac gttgcaatca tcattgaagt
    28501 agccgcgatg aatttccgtg cacgtacaat gggctttgac gcaacgaaaa catttgaaga
    28561 aagattaagt cgcttgattg aagaaaactc aggcaacgac tagcaaggag tgacaatatg
    28621 ttagcacaaa tcaatcgagt tgcttttgag cttgtaggga ttcctatcta ctggtatgca
    28681 ttgatcatcg tatcaggtat cattatcgcc atgtggctta gcagcagaga ggctgttcgg
    28741 gtaggattaa aagcagatga tgtgacagat tttatgttgt ggggattgcc tatctccatt
    28801 attggcgctc gcttatatta tgttttattt gatcttcccc agtatatagc tgatccaatc
    28861 caaatattca atatccgttc aggaggctta gctatttatg gcggactgat tgcaggcgcg
    28921 atcacgctgt atttttttac taaatatcat tttatttctt tgtggacttt tttagatatc
    28981 gctgcaccaa gtgtattatt agcacaagca atcggtcgtt ggggaaattt catgaaccac
    29041 gaagcatatg gaccagacac gacgcgaagc ttcttagaaa gtctgcattt accgcaattc
    29101 atcattgata atatgtatat cgaagggatc tatcgtcaac caacatttct ttatgaatca
    29161 ctttggagtt tgattggatt tattttgctt ttgtttttac gaaagaaacc acaccttttg
    29221 aaaaaaggtg aagtcctttt atgttatcta atgtggtata gtttcgggcg tttctttatt
    29281 gaaggattac gtacagacag tctttacttt ttaggtgtga tccgtatttc tcaattatta
    29341 tctgctgtgt tatttgtcgg tacattgatt ctatttattt ggcgcagaaa aaaaggaaat
    29401 ttaccggatt atgaccgctc attaggaaaa aatcaacaaa ttatctgatt tttagagcgt
    29461 taaaaatgaa aaaaatttca ggagtggtaa aatgaattat agagtagcgg ttttaggacc
    29521 aggctcttgg ggtactgctt tggcacaagt cctcgccgaa aacggacatg acgttcggat
    29581 ttggggacat cgtgcttcac aagtagaaga aatcaacacc caacacacga atcaacgtta
    29641 tttaccagat cattgtctac ccgattccat ccaagcattc accaatatgg aagatgcagt
    29701 aaaagacgca gatgcggtgc tattcgtcat tccaacgaaa gcaatacgtt ctgttgcaaa
    29761 agaactagtg cctaaattga atacaaagcc agtgatcatc catgcaagta aaggattaga
    29821 acaggggaca cataaaagga tctctgacat cttgttagag gaaatcccag tagaaaaaag
    29881 aaaagctgtt gttgttcttt ctggaccaag ccatgcagaa gaagtagcga aacatgacat
    29941 cactacgatc acagctgcaa gtacagatgc aaaagcagca aaatatgtac aagagctgtt
    30001 catgaataat tattttcgga tctataccaa tcctgatgtg atcggtgtag agatgggggc
    30061 agctttgaaa aatattattg ctattggtgc tggcgctatt cacggcttag ggtttggcga
    30121 taatgcaaag gcagcaatca tgacgcgcgg attagctgag atcagccgtt taggtgtagc
    30181 aatgggtgcc aacccgctga cctttatcgg attaagcgga gtaggcgatc tagtcgttac
    30241 ttgcacaagt gttcattcta ggaactggcg cgcaggcaac ttgttaggac aagggcagcc
    30301 cctagaagag gtgctagcca atatgggaat ggtcgttgaa ggtgtgaata ctacccaagc
    30361 agcgatggaa ctagcccaaa taatggaaat cgaaatgccc atcactcaaa caatctatga
    30421 agtgctgtat gaacaaaaag aaatcaaaac agccgcaaaa gaaatcatgt tacgtgatgg
    30481 gaaaaaagaa aatgaattct cattaacaat tttttgaagg agcgaatgta tatgaaagtc
    30541 aaaaaagcag ttattccagc agcaggatta ggaacaagat ttttaccagc aacaaaagct
    30601 atggcaaagg aaatgttgcc aattgttgat aaaccaacaa tccagttcat cgttgaagaa
    30661 gcgttgaaat caggtatcga agacatcttg atcgttacag gaaaagctaa acgaccaatc
    30721 gaagatcact ttgattcaaa tattgaatta gaaacaaacc taagtgaaaa aggaaagacc
    30781 gaattattga aattagtaga agaaacgaca gatgtcaact tgcatttcat ccgtcaatct
    30841 catccaaagg gtttaggaca tgccgttctt caagcaagag cctttattgg aaatgaacca
    30901 tttgtcgtta tgctaggcga tgatataatg gaagacgaag taccattgac acagcaatta
    30961 atcgatgatt acgaacgtac tcatgcttct acgatcgccg ttatgcaagt tcctcatgat
    31021 gaaacttcaa aatacggaat tatcaatcca ggagaagtat tggaagatgg gttatacaat
    31081 gtcaaaaact ttgttgaaaa accagatcca agcaaagcac caagtgattt agctattatt
    31141 ggacgttact tattgactcc agaaattttt gatgtattgt ccgagcaaca accaggagcc
    31201 ggaaatgaaa tccaactaac tgacgcaatc gatacattga ataaaacaca acgcgtattt
    31261 gcccgtaaat tcacaggtaa acgttacgat gtcggtgaca aatttggttt tatgaaaaca
    31321 agtattgaat atggtctaac acatccagaa gtaggtgcac ctttacgtga gtacatcctg
    31381 tctttaggta aaacattaga agcagaagga agcaagatcg atcataatcc aaaaggaata
    31441 acagaaatca aagaagaaaa gaaaaaataa cccttttttc taacgagctt cagctgctaa
    31501 ttgaataaaa agtagttgaa gctcgttttt atttgtttaa aaaacacgaa aatgctatcc
    31561 ttatagaaaa gagagacaag aagggagttt gatcatgtca ggaggagaaa ttgcaggatt
    31621 gatcgcagca atcgcctttg cgatacttgt cgtttttatc gttcgtgtgt tgttgcaagt
    31681 ttctaaaact ttagaaaaag tagatcagac tgtagcagaa gcaaatacga cgatcgaaat
    31741 cgtcacaaaa gacgtagatc ttttgtctag acaagtagaa ggcttactgg tcaaaagtaa
    31801 tgaactgctc ttggatatca atggaaaagt cgcaacgatc gatccattgt tcacagcagt
    31861 tgctgattta agtgaaagtg tatcagaact taatcattct agtaaaaaca tcgcgacgaa
    31921 agtcggcgga atcggtaaaa cgacagctaa agcgacggtt gccggaaaag tcggtgggac
    31981 agcgatgaaa ttttttaaaa acaaaaaaca tactgaaacg acaggaggaa aataaaaatg
    32041 gctaaaaaag gtggattttt attaggtgca gtagtcggag gcacagccgc agcaatcgcc
    32101 gcgttattgt tagcaccaaa atctggtaaa gaacttcggg atgaattagc tgcccaagcg
    32161 gatgatttga tggatatggc ttcagattac acagatatgg cgaaagaaaa atcgactgag
    32221 ttaacaggta ttgcaaaaga aaaagcgcaa gatctttctc aacaagcagg tgatctagca
    32281 ggtagtgtca aacaaaaagt aagtgaatca gcagatgaag caggaagtga atctgacgat
    32341 atcttgttaa atcttaaaga acaatcagct gacttatcta atcgtttcaa aaaaacggca
    32401 gaagatatga aaaaacctgc agatgaatta ggaagtattg ctaaagatac ttcagaagat
    32461 atcataattg atgtaaaaga cgctgctggt aaagcaggag atactgtcaa tgaaggaatg
    32521 tcagaagcaa aaccagttgc agatgactca aaagaaatga tgaaaatggc aaaagaagat
    32581 gcgaaagaag ctaaaaaaga aataaaagat acaatgacag attcatctac aaatcactaa
    32641 aatcacaaat ttatagaata aa
//
LOCUS       DARPZF010000027        30718 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.028, whole genome shotgun sequence.
ACCESSION   DARPZF010000027 DARPZF010000000
VERSION     DARPZF010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.028"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            311..1090
                     /locus_tag="SLE65_001616"
     CDS             311..1090
                     /locus_tag="SLE65_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448912.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSYVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
     gene            1136..2080
                     /locus_tag="SLE65_001617"
     CDS             1136..2080
                     /locus_tag="SLE65_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEI8448913.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVAIVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            2096..2875
                     /locus_tag="SLE65_001618"
     CDS             2096..2875
                     /locus_tag="SLE65_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HEI8448914.1"
                     /translation="MEETINLEEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            2887..3585
                     /locus_tag="SLE65_001619"
     CDS             2887..3585
                     /locus_tag="SLE65_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HEI8448915.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3613..4377
                     /locus_tag="SLE65_001620"
     CDS             3613..4377
                     /locus_tag="SLE65_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEI8448916.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEWLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQITAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            4422..5111
                     /locus_tag="SLE65_001621"
     CDS             4422..5111
                     /locus_tag="SLE65_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEI8448917.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFCHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYISHRSLMYDLRLILKT
                     FYVIVKPNGAY"
     gene            6338..7018
                     /locus_tag="SLE65_001622"
     CDS             6338..7018
                     /locus_tag="SLE65_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEI8448918.1"
                     /translation="MIGIEEKKGVQKDVTIDREENLRGHRFYWIGRRAQDIFFSALAL
                     IALSPVMLITALAIVIDDPGGSPIFVQDRVGRNGKLFKFYKFRSMCVDAEAKLEALLA
                     QNEMDGPVFKIKDDPRITRVGKFIRKTSIDELPQLWNILKGDMSIIGPRPALPREVEQ
                     YGDYERQRLFVQPGLSCYWQIAPHRNELSFEEWVELDVKYINERSFITDWKIIFLTLQ
                     AVLFGYGE"
     gene            7047..8360
                     /locus_tag="SLE65_001623"
     CDS             7047..8360
                     /locus_tag="SLE65_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEI8448919.1"
                     /translation="MNIILLSGGSGRRLWPLSNDIRSKQFIKLFKDENGEYESMIQRV
                     YRQITTVDPDAKVTIATSKSQASAIHNQLGDKASICVEPCRRDTFPAILLAAAYLHDE
                     LGVGDDESVAVCPVDPYVDNSYYEGVEALEKLVQQNTANLTLMGIAPTYPSEKYGYII
                     PESSNEVSTVKEFKEKPDKATAEKYLAQNAVWNAGVFAFKLGYLLEKAHAMVDFEDYR
                     DLYSKYETLTKISFDYAVVEKETSIQVMRYNGDWKDVGTWNMMAEVMADNIKGKAVMD
                     DTCVNTQIVNELNIPILAMGCKDMVIAASGDGILISDKERSGYMKPYVEKISTEVMFA
                     EKSWGTYTVMDVQEGSMTVKVSMQAGQKLSYHYHNSRDEVWTVVAGQGKAIVDGMKQI
                     LRAGDVVTIAAGCKHTIEAVTNLDIIEVQIGETISVADKYKSSLN"
     gene            9166..9933
                     /locus_tag="SLE65_001624"
     CDS             9166..9933
                     /locus_tag="SLE65_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HEI8448920.1"
                     /translation="MGIEGGYLMSRMRFMNTEIDNLTMGEVLVEVEKMIQDRRCGYVV
                     TPNVDHIVQLETGKELQDVYKNASLILTDGKPLIWISKFYKTPIKEKISGSDIFSLLC
                     KMAAEKGYTMYFLGAAEGVAAKAADNLMKRFPGLNVVGTYSPPYGFEKDEDEMFKIDS
                     QIKRANPDMLIVGLGCPKQEKFMFYNCDRLGVPVSFGLGASLDFEAGNVKRAPKWMSD
                     YGFEWLFRITQDPKRMAKRYLVDDLKIFKLALKYRKK"
     gene            9960..10961
                     /locus_tag="SLE65_001625"
     CDS             9960..10961
                     /locus_tag="SLE65_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEI8448921.1"
                     /translation="MIITKTPFRMSFFGGGTDMEDYFRENGGAVLSTTFDKYCYVNVR
                     HLPRFFDYSTELSYSRTERVTNIEDIEHPAIRNAMKMLDMHEIRLTYEADLPARSGLG
                     TSSSFAVGMLNAFYALKGKYADKKKLVDKAIYLERVLCNEAGGWQDQIAAAYGGFNRI
                     NFNSDGYEVLPIIITPERKKQLNNNLMMFFTGFTRFSSDVQKANNVSGTEDKRVRLKK
                     MYELVDEAEAVLTDKNRDLDDFGRLLDLTWRLKKATGGAISTGSIDELYEKGMAAGAL
                     GGKLLGAGGGGFLVFYVQPEKQNAVRSAMSNLMYIPFEFENGGTQVIHYTPEMYIPK"
     gene            10984..12270
                     /locus_tag="SLE65_001626"
     CDS             10984..12270
                     /locus_tag="SLE65_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIIA family hydrolase"
                     /protein_id="HEI8448922.1"
                     /translation="MKVVIMAGGKGTRISSVASDIPKPMIKIENKPVLEHEIECLRDQ
                     GFTDIILTVSHLGDIIMNYFGDGSGISPVTGQPFDVKIEYFLEKEPLGNAGALFRLKD
                     NLTEDFLLLNADAMFDVDFNRFVAYHREKGGLVTLFTHPNSHPYDSGLIIADKDGSVD
                     RWLVKEDSRPTYYRNRVNAGLHVISPAVLDVEINTPKIDLDRQLLKPLAGTGKMFCYD
                     SPEYVKDMGTPDRYYAVCEDFKAGRVKGKNLQNKQKAVFLDRDGTINQYVGFLRHIDE
                     FELIKGTEDAVKKINAAGYLAIVITNQPVIARGEVSFEELEEIHNKMETLLGYKGAYL
                     DAVYYCPHHPHKGYEEERPELKFDCECRKPKPGMLIQAATDFNIDLSQSWMIGDGEND
                     IKAGQAAGCKTALVGESEYGQDMTIATLSEFADKIC"
     gene            12304..12957
                     /locus_tag="SLE65_001627"
     CDS             12304..12957
                     /locus_tag="SLE65_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEI8448923.1"
                     /translation="MIDNRLQKHIDLLIKRYPTLEVIKQDIVDGYLIMEECYLNDGKL
                     LIAGNGGSAADSEHIAGELMKSFKTPRPVSREFADKLIAVDPVKGSELAKNLEYGLMA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRPGDVFLGISTSGNSKNVINATVVARA
                     LGMKVIGLTGAKGGELARVADVCVKAPETETYMIQEYHLPIYHCWCLMLEDKFFGNR"
     gene            12990..14195
                     /locus_tag="SLE65_001628"
     CDS             12990..14195
                     /locus_tag="SLE65_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEI8448924.1"
                     /translation="MNVLFITTQFPYPLDNGGKIGAYNGISVLSRDYDVTVLSFTEEP
                     QYVEEGVSFFREKFNSVKFENPVIHDVHIRNNPMKLVEALAIGYCLRQPYIVSKFYDS
                     KMLQLIDEKFSNNAYWDIIFIDYLNMQSYGQYIREKYKTQFGKYILKDHNIEYDLVLQ
                     EAESSRGLKKKLLQLEYKRTRKYEEAAVNRADYCFSVCDANTEVLKKINDNSYTMLPT
                     YEMLTGVKKNIEKNTILYLGNLSWKSNMQGLVWFLESIYPNIQQRIPDVKITIVGSGP
                     VGTDFSKYSGVDYRGYVKDISHIYDDQAVLIVPLLEGSGIRIKILEAFNNEIAVVSTL
                     VGCDTIGAKDGSELFIADNEKDFATAVVRLLEDMNLNEKVRKNAKLFLKEKYSLTARQ
                     DEFSAIINS"
     gene            14325..15650
                     /locus_tag="SLE65_001629"
     CDS             14325..15650
                     /locus_tag="SLE65_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448925.1"
                     /translation="MIVAAMSYHLTGNSNVASLIAVVGVVYAIVKACNNEYLAIWVMF
                     VLGSDIWGIVPYINIGSGVLHWSDFNVIVAIFLCLRFIKVKARSRYGIVYSVMLIFIL
                     IACVQSHSIYGQDVHTTLLTARELLVVISFWPIVKIVYSERITKNEFIDLVCKFTRWT
                     MCIYWFEWILVNMGFNITFLQTGARWGTRIYIDPIFIILYFFINLYAVIYKREGYNST
                     NKSIWNCIFSLLTFVIISQGRSGILYVVITSVIMLLISLKPSKIIRFGILGIALIACL
                     VSVTQIREVVISSFVESQSSDTGNIAYRIAEQDYFENKLEGHELFGVGIPNNHDARAV
                     EYSGKTIDFESKKYNPYYLEDLGAFEIRYRFGIIAYALYIVALAISIIDAGFRRDKSV
                     AAFAGMAFMVFMALNFNLLAYITARPFGFMISLILIEISAFNDEFIYIE"
     gene            15667..16797
                     /locus_tag="SLE65_001630"
     CDS             15667..16797
                     /locus_tag="SLE65_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448926.1"
                     /translation="MNLDRLKKIANMISPIIKVINAPLAYFSGKSDYMEKGILWPTVT
                     TYSNNSRKVIQYTTLPKNVDNMAQMQWAGESFEDICIVLQGPVLEDGDFTLNTVKMYN
                     KYYPKVKLVVSTWIGLSEETECKLREAGADVVLCKKPEKTGAYNINLQLTSAYEGVKM
                     AQKLGCSYALKTRTDQRLYANDVLKYFQTLLNIFPSSDCKVVNQRLIFTTYGKSFRYL
                     PFNLCDFLVYGETSELLKLYGIQRDNRASDFGKIIYTEEKEFNKKIFTLLEGKQGVSP
                     YDVFPDFDALYKKYMFAEYYIVYNYFLENIASNESYGDLMDAYYSYLKKYAVVADSEK
                     LLLYWPKYVQYNVKFENELDFYAKLDSKKWMDIYANYTPFSQ"
     gene            16823..17908
                     /locus_tag="SLE65_001631"
     CDS             16823..17908
                     /locus_tag="SLE65_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="HEI8448927.1"
                     /translation="MKIGIVTIVNGASFGNRLQNYATQKVLENNGYTVETINNCFDKE
                     GTLSIVIKNAIYTLFKFIPHFKKSKSIWKRMYTFYQWDKQYIDYSHRKIDASKKNSFV
                     SIKNDYDYFLVGSDQIWNPKYAANKGFELLSFVPNEKRVSLSTSLGVPSIPSDLEKLY
                     VTEWNKFKSISVRENQAAKIIEDLTGTTAAVHIDPTLMLERSEWEAFQKKPDNIDENY
                     ILSFFLTNPPKDTVDVLDKVAKDLKIGVLTLDASWEYFQDITPNHFVYLISHARMIYT
                     DSFHCTVFSLLFGKPVVVFDRFDSEKMNSRLSTLLNKVNKAHFWVGKKADEAMIRAIA
                     SEPEYDIDKLMVSERECVKAYLKEYLQ"
     gene            17931..18746
                     /locus_tag="SLE65_001632"
     CDS             17931..18746
                     /locus_tag="SLE65_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448928.1"
                     /translation="MEHLSDCFGKMKIVTTSCAREYFKDDLDKSEYSCFVDSRAAMFF
                     AMGQALAKRRNVVVMLADELTSCYTALTECAFQQVDLIVFAFQTVRHEIDLASLKNCG
                     CNLINCSAQDDIDRVVSNTKGLNQTTVIKINMNCESDKDHICEYIDLPDIPVFFHGSL
                     YSPASKKKYEQYGQVSKYLGYLVGGKDAILIISHNEFLNDISVWINYYSFGEIQPKII
                     IFDSPNDYQYKWLCDLECSVAHSTNRFLSEDLALLQNNGISIVLRGDNYDIVS"
     gene            18730..20448
                     /locus_tag="SLE65_001633"
     CDS             18730..20448
                     /locus_tag="SLE65_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylase"
                     /protein_id="HEI8448929.1"
                     /translation="MISSVKNVQILVSLLKQHNIKDIVISPGSRDFQLVHSVETDSFF
                     RTYTVVDERSAAFFANGLSMAIDKPVCVCCTSSTASSNYMAAAKDAFANGIQLVLLTA
                     DRDYRRLYQMEDQMIDQVDMYGAYVRSNVDIPIVKDSDDEWYATRKINEAILELNHGV
                     KGPVQINYQLMDLSAPFVETMPEYRKITRYQEDDLLSSVEIFKQKLLSKKRIMVLCGQ
                     QEENNLSALLEEFFIKYNTIIIKDNYSNIHGEHFIKTVLVTERMSVNAFIDYCPDLVI
                     TIGKHVWSFVKYTLRDKKLKFEHWRISEDSKIVDPFNKLTSVFQCSAEFFMETVTAGV
                     NSNNNLEYYNLWKTRLSKVCYPELVYSNFYAISELVKKIPDSALVHSSILNAARLYDF
                     VSDDKALLSFANLGADGIDGCLPTFLGQAEADKTRPAYLISGDLSFFYAMNSLCGDIP
                     DNAHIFLINNHSGSEFHTNFGKFYNGSLSVDKHIAAGHISNAKDWALENNIKYITADS
                     KESLKSGLDVFINTFDSPVLFEVFTDPDTDTSVLESFYSINKVITPKMYFRKALDIIK
                     KHLHIK"
     gene            20474..21310
                     /locus_tag="SLE65_001634"
     CDS             20474..21310
                     /locus_tag="SLE65_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8448930.1"
                     /translation="MAIKSYIKRLLLYIRHGDPKINLDVSYLSEGAMLAGKTVIITGG
                     AKGLGFAIAKSFIAQGASVIITGRDMDSLNNAKCQLGDMCSIRAFDITDAKMYRTFFE
                     DAYETFGRIDILLNNAGISLHEDGFMSVTEKTWDKQMDTNLKGVYFFTQEFIKFVKEK
                     NQMQANIIMMSSERGLCGDSIPYGLSKAAINSLVVGLSKKYISEGIRVNGIAPGVTAT
                     AMTGISEKGNLYNPATIGYRYFLPEEVAQVALFLASSLSNCISGEIIACDQGQYLSRN
                     WG"
     gene            21315..22748
                     /locus_tag="SLE65_001635"
     CDS             21315..22748
                     /locus_tag="SLE65_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEI8448931.1"
                     /translation="MGILLKKYNSLSEPAKASIWFTLCNVLQKGILFLTTPIFTRMLS
                     TAEYGKYTIFISWYSIIAIFTTLNLSAGVYNKGLIKYENKYALTSSFLGLSSFISLCA
                     LMLYLPFRTVINGLLDLSTEFVILILIESIFEPAFLLWSVKERFDYKYQKLVLITVLM
                     AVLNPGLGIILILSFGEYAIWRVRAYVVVNVVVGMFIGIGILAKGKKLFDKEYWTYAL
                     RFNLPLIPHYLSMTLLNQVDRLMINSMVGASEAAIYSIAYTISSMMNIITTAINGSFI
                     PFTYKAIKDGVYEKIKSVANQLLVLIFVLCSFTMLFGPELIWVVGGEKYMDAVWIIPP
                     VAASVFFMFLYPLFGNIEFYYEKTNYVMFASCVGSIAKIISNYVSIPRFGYISAGYTT
                     LICYMLFSFAHYMFYKKILRENGIKEDMYNIKNIIFLSVLMIVLTIGMTILYFSTILR
                     YSIIIGLVIVAFLKRTQIMKILKNIKN"
     gene            22786..24426
                     /locus_tag="SLE65_001636"
     CDS             22786..24426
                     /locus_tag="SLE65_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HEI8448932.1"
                     /translation="MRLLIPSAKIVPEELHHLGKLPAIIYPINQKIVFDYLYDQYKDV
                     CSAIDIACYEKMDKVARRLDKYIKSKTVNIIQLKELGDLGRTIYDSLIGCDEPVIINF
                     ADTIINDNIYSLECDSFFYAEDYYSNTWTFFEEKDGDIISVLDKNELKEDDGKKHKLF
                     SGVFQIMDAQYFRECLRKALMSNVVNVNSFYQALQEYSKRYEFLSIKTNNWFDIGHAD
                     KYYNSKLEVKAREFNHISIDKDRSILRKISEDVEKFIGEIKWYLKLPAQVEYVRPRIF
                     EYSTSYINPYVSMEYYSYHTVHELFLYSDLTKKQWIDIFNRIRFVCSDFKRYSVSGDN
                     IQKSLKDMYLDKTFQRFNKLRKDPRFTEFFSSDIQINGVRYKSLDQIEALLSVSVPRE
                     LFDITQFNIIHGDLCFANIMVDNTFSFIKVIDPRGKFGDFDIYGDYRYELAKLFHSVD
                     GKYDFIIKDLFTIKYDPKKAIIDYIVQDRKRDYDLYEVFYSVFKDEIGSDLKKIELIE
                     ALLFLSMIPLHGESLNHQMAMLATGLEILGRVVPDIYC"
     gene            24514..24912
                     /locus_tag="SLE65_001637"
     CDS             24514..24912
                     /locus_tag="SLE65_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HEI8448933.1"
                     /translation="MFKDYAFVFDIDGTLCPIKKKDEKYEDLVPYANMVEKLRYYKEN
                     GAKITLFTSRNMNSYHGNLGVINANTAKILLAWLDKWEIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLSCTLDQLDEICKKSKLKSE"
     gene            24937..25653
                     /locus_tag="SLE65_001638"
     CDS             24937..25653
                     /locus_tag="SLE65_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEI8448934.1"
                     /translation="MTVIITMAGLGSRFRKVGYTVPKFMIEAKGKTLFDWSLDSLLDY
                     NSHVEKYVFVVRKEDDATVFIKEHCSLYGIENVEVVEIDYMTDGQATTCMLAIPYCAP
                     DNAIMVYNIDTYVEPGEMKYVDISGEGHIPCFHADGDHWSFAKLNEYGDVVEVREKVR
                     ISNNCTLGAYYFSSAKLYASLYEEYYADERHLEKNEKYIAPLYNYMIEKGMKVTISIV
                     DKSKVHVLGTPEELDVFLNE"
     gene            26885..27464
                     /locus_tag="SLE65_001639"
                     /pseudo
     CDS             26885..27464
                     /locus_tag="SLE65_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317850.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
     gene            27524..29176
                     /locus_tag="SLE65_001640"
     CDS             27524..29176
                     /locus_tag="SLE65_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEI8448935.1"
                     /translation="MDHNANYYHWLTNANAEIVEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLSDYLNKTYETPSVVVGYDSRIKSDVFAKVAADIF
                     AANGIQVHLWPELLPVPTVSFAIRYLKASAGVMITASHNPSKYNGYKVYGAGGCQITT
                     EAAAEILAEIEKLDIFADVKMGGDASRIASIQPEVLTAFIEEVKGQSVLFGEEVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEINEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKNAEGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PTDPVMVKTIVTMDLGERIASNYGVRTVDVLTGFKFIGEQIGMLEKAGKVDSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLFDKLNEIYAKYGYCLNTLHSF
                     EFEGAAGFTKMQKIMVEFHKGLDMIGGKKVIETLDYSTGLNGLPKSDVLKYLLEGNCS
                     VVVRPSGTEPKLKTYISVSAESKEAAEVMEAVMAAELAEMFK"
     gene            29520..29885
                     /locus_tag="SLE65_001641"
     CDS             29520..29885
                     /locus_tag="SLE65_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEI8448936.1"
                     /translation="MYYFQQSYLPAILNKAISIGDTGVHIFFFCSGFGLYLSYLKKPI
                     TLGEFLQKRFIKIYIPYIIVITVSVLLPYMTQDLNAAKVYLSHVLLFKIFLPVYEESL
                     GPFGLFRQLFSSISYSYQL"
     gene            29973..30416
                     /locus_tag="SLE65_001642"
     CDS             29973..30416
                     /locus_tag="SLE65_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448937.1"
                     /translation="MEAYEFLGAALRNIFGNLLSACLVAEYLVKRKIVRFNNIFVIMA
                     SIVGIGFAGISKIIGGLMESINDIFAFFGYGAIAILMYQVIPFRKIMPRISRYSYDIY
                     LLHILVFSTIHQIIPNLVLAAFVSIPITLVLSYYYSIMLYRLKLK"
     gene            complement(30571..>30718)
                     /locus_tag="SLE65_001643"
     CDS             complement(30571..>30718)
                     /locus_tag="SLE65_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HEI8448938.1"
                     /translation="EKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRY
                     SLGY"
BASE COUNT        10005 a         4479 c         6588 g         9646 t
ORIGIN      
        1 tattattaat tcaatgttaa tttttttgtt attttatttt ttgtgtaact tttaaaaaca
       61 cctatgaaaa ttaaggaaat aaaaatgaaa tcgattaatt gttatcttat taatgtttta
      121 tttactttta aatcataaat tgccctagtc aagaaaacag tttgtggtat gattatatag
      181 ggaaaacttg tttacaaata tttctgtgaa tatattagtt taattatgtt ttttaaaata
      241 aaaagctgtc atttttatgt aagtgaatta tatcttaatt tatctatcat caatacttag
      301 gagtgaatct atggaaaagc cattcgtcaa gtcattgact gctgtggcgg taggtgcagg
      361 tgctattgcg atctgtttgt ttggttacca tatcaataat cagcggcaac atcagcaacg
      421 gatcaattat gcagaatctg ccatcaccaa tcaaaaagac accttgactt ctttatcaaa
      481 agaagtagac aagctgtata gtacaaaaga aaaaattttt ctaaaccctg aaataacaga
      541 agaaacaatc acaagtttgt caaataagct atcctatgtc aaactttcag cagatgatta
      601 cgacatcaaa gaatcagaat tgcctaaaga agctgttgca atccaagatg agaagaaagc
      661 aatcgtgaca cagttagata gtgcagaatc aaaactgaag atccagacag ctgtcaacga
      721 tttgtttact aaaaatgtat caaactggca gcaagctgta gacgatgtca tcatcaaaga
      781 aaaggtgaca agtgcagatg tcgctcgtgt acgtgaaaat atgagctttt ttaaagatag
      841 tccttggaaa acggttgtta tgcaatattt aggattcgct gatactcaga tcgcgcaagt
      901 cacgcaacta gatcagttat tcgatacgat gttgaaggat ggtcaagtga ctgccaccgc
      961 tacttacgat caatatttga cggcgctcag tcaaatagag cagatccgga atgaaaaaat
     1021 aagcgcagca tacgcaacaa aagcacaaac tgttgctcag caaatgggct atagcaatat
     1081 aagttattga cagttaaaac gttgattcaa gcaaggttag caaacggagg aaactatggc
     1141 aagacgaaga agaaaatcaa gagggaaaaa aatatttctg attattttag cagttcttat
     1201 cgtattagta ttagcaattg taggagtagg agcaaaatta tatctggatc tctcacattc
     1261 tattgagaaa acttacgaat cagtggaacg aacccaagga gaacgaacga aaccagttga
     1321 tctggacaaa caagaatctt tctctgttct attgatgggg attgatactg gagatttagg
     1381 tcgggtcgat caaggaagat cagatacgat gatggttgcc atagtcagtc ctgaagacaa
     1441 acagacaacg atcgtcagca ttcctcgtga tacgtatgtc gacatcgtag gtcgtgacac
     1501 aaaagacaag atcaaccacg cttacgcatt cggcggagct gccatggcga tggataccgt
     1561 acaaaaatat gtagacatcc caatcgatca ctatgtctct atcaatatga aagggctaaa
     1621 ggaacttgtt gatgcagttg gtggtatcga agtcaataat gacctcactt tctcacaaga
     1681 tggctatgac tttacaatcg gtaaaatcac attgaacggg gatcaggcat tatcttattc
     1741 tcgtatgcgt tatgaagatc caaatggtga ctatggtaga caagagcgtc aaagaaagat
     1801 cgtagaaggt gtagcaaaaa aagtattgag tttaaacggt gtcagcaact atcaatccgt
     1861 tttgaatgct ctagagtcga atatgaaaac agacatgagc tttgatgaaa tgaaaaaaat
     1921 cgctttagat tatcgggagg catttggtac gatcaagcaa gatcagctgc aaggagaagg
     1981 ctttatgcaa gataatatct cctatcaaaa agtcagtgat caagaacttg atcgtgtaaa
     2041 aaaagaatta aaagatcaaa tgaatctaga gaataaatag gaaagtggag aaaaaatgga
     2101 agagacaatc aacttggaag aaatttttga aacattacgc aaacacttgg taacaatcat
     2161 catctcaatg tttgctggct tggccatctc aggaatcgta acatttttca tcttgacacc
     2221 aaaatacagt tcacaagcac aattgatcgt gacactgcca caatcagaca cagcaaatgt
     2281 caatgatgtc aatacgaacc tgcaaatgat caatacgtat aaagatatga tcgtcagtga
     2341 tttagtacta aatgaagtca aagatcgttt agaaacagaa gacaatgtga aaatgactgc
     2401 tggacaaatc aaagatgcga tctccgtcaa tcagtcacaa aattcacaaa tgttctcgat
     2461 ccaggcaata agcacgaatg cagtgactgc tcaacagatc gctaacacaa cttcacaagt
     2521 tttccaagag aacgcaaaag acgtgatgaa tgtcgataaa atctcgatta tttcaggtgc
     2581 agttgccaat acgacacctg tttcgccaaa taataaattg aatctagtga ttggcttagt
     2641 attaggaatg atggtaggcg taggtctggc attcttattc gaattacttg atcggacagt
     2701 gaaagatgaa aaatatgtga cggatgcatt aggattccca atcttaggaa cagttccaga
     2761 aatgtcagcg aaagaattga acgctggtat ccgtaaaaaa ggaacagctc ctgcacgacc
     2821 aaaagctaca aacgataaaa cagccccatc acgcagaagc cgctcaagag tctaggagga
     2881 agaaaaatgg cacgaacaca gaaacaaaaa gcagcacaaa ctcatgcagt cagtttgatc
     2941 acattaacaa acccatcttc accaatcgcc gaacaatatc gtacgatccg gacgaatatc
     3001 cagtttgcct ccgcagctgg tcagcaaatc aaaacgattg tcgtgacttc atcaggtcct
     3061 ggagaaggaa aatccaccac tgcagcaaac attgcagtcg tttttgctaa atccggtcaa
     3121 cgagttctac tagtcgatgc agatttacgt aaacccgtcg tctataagac attccagctg
     3181 aacaatgcca ggggattaag tacagcactt agttcatcag gaagtgtagc agatgtaatc
     3241 caacgaacgc cagtcgagaa cttgtcgatt ttgcctagtg gacctaagcc acccaaccca
     3301 tcagaattgt taagttcgcc aagaatggat cagatcctag acgaagcaag acagttattt
     3361 gacgtggtga tattcgatat gccaccagta gtagccgtaa cagatgcaca gatcatgtct
     3421 tcaaaaacgg atggcacttt attggtcgta cgtgaaaata catcacgtaa agaatcattg
     3481 aataaagcaa aagaactgct agagatggta caagcacgag ttttaggtgt tgtatacaac
     3541 ggagcagaac atagcaaaga tgctggttat tactacggaa attaaggaat aagaagagag
     3601 gagacaagag aaatgatcga tctacattgc catatcctac caggaatcga tgacggggca
     3661 gaaaacttag aagcaagtat tgcaatggct gaaaaagcga ttcagcaagg catcacgcat
     3721 attttatgca caccacacca caataatgga aaatacagca atgaaaaatc acaagtcatt
     3781 tctctagtcg cttcgttaca agccgaatta gagaaaagac agttgccttt gacgttattg
     3841 gaaggacaag aagtacgtat taccggaacg ctcatcgaag acatccaccg agatgaaatt
     3901 ttatttacag atttagatga tacatatctt ctgatcgaat ttccgacact ggaagtgccg
     3961 ttatatgcag aatggctttt ttttgagttg ttagaactag gaaagacacc agtgatcgtc
     4021 catccagaac gcaacgcgca ttttcgagaa gacccaaatc atttgcttcc gttcctagat
     4081 atgggatgtt tggcccaaat tactgcgcca agttatgttg gtgtatttgg caaagacatt
     4141 cagaaaacag ccaaaacaat ggtcaaacat aatctcgtgc agatggctgc ttctgatgcc
     4201 catggggtct ctaagcgtac cttttactta aaagagtgct atgagcagat tgctaaggac
     4261 tttggtaagg aaaaagtagt acagatgaaa caagtcgcaa aggatctgat caacggggat
     4321 gaaatcagtt atccagtcta tgaagaggta aaaaagaaga agtttggttt attttagttc
     4381 tttattcgta gataaaaagg aaatgaggag agagggaaag tatggaaagt gaagatttat
     4441 tatctcgtat tagtgaagta catcctaatc aagtttggtt ggataaagaa aaagttgaaa
     4501 aacgatatat ctatttattt tttaaaagaa tgattgatat tgtaggaagc attattggtt
     4561 tgattttagc ttctcctttg atgttctatg tagcttatcg aatcagaaaa gaagagccag
     4621 gaagtccgat atttttttgc catacacgtg ttggtaaaaa tggaaaaaca ttcaaaatgt
     4681 ataaattccg ttcgatgtgt ttagatgctg aagaaaaatt ggaagaatta cttgatcaaa
     4741 atgaaataga aggtgcaatg ttcaagatga aagaagatcc ccgtgtcact aaaataggta
     4801 aaattatccg tgccaaaagc attgatgaat tgccacagct atggaatgtt ttaaaaggcg
     4861 atatgagtct aattggtcca cggccacctt tggagaggga agtagctgag tacacgagat
     4921 atgatcttca acgcttgtat gtaaaacctg gttgttcagg tttgtggcaa gttagtgata
     4981 gaaataatgt tagtttccat aaaatggttg agttggattt agagtatatt agtcatcgaa
     5041 gtttaatgta cgacttgagg ttgattttaa aaacgtttta tgttattgtc aagcccaatg
     5101 gagcatatta gttagggata gaatgatgga ttgttaataa aaaagattac acatgttcat
     5161 attatcgttt caaaagtaat aactgtaatt atggagggtt tgaatcactt gtagaaaatc
     5221 taaaaaaaga aaggtgaatg gggcaattca gtatcattat tcttatataa aagaaaatat
     5281 tcgaaatttt gggatgatac cactcttaaa tataatgatc taaatgcttt aatattggta
     5341 tatccgatat aggaactgac gagctattta gtatgataca aaagtatatt gatagccatt
     5401 aataaatttt ccaaaaaata atgacagcac accaattttt ataatttagc ttgttgaatc
     5461 ggtatgttca tgggacggtt caaaaaaaga atcgaaaaaa taaacggtaa aattttagtg
     5521 aatcctatgt aataaaattt ggatagatgg aaaaacagca cataaggagg ctgagtttgt
     5581 tgtcatttct gctcctacaa actatggtag tgaatgtgtt attgaattag tgatgtctgt
     5641 tacttcagag acattgggga taattaactt cactatacct gtagggtata caaaaaatgg
     5701 aagaaaaaat attatcaata gattttattt agttcagaat ttttacgtgg aagtaaatta
     5761 ttgatgataa tctttatcca attagaatta ttatcgtagg atgtgatgat gatagccgtg
     5821 aagttgttca agtatttacc aatgtctaca acgcagaaaa ttagtttggg tttttcggat
     5881 tggaaaattt caatgtataa aatcataaat ttgctgtaaa tagacagttt ggggtagtaa
     5941 tagcccaata aattgttcga taaactcatc tttggggtga gaatagctca atcattgaat
     6001 ttcaaacctg cctttggggt gggattagag gtcaatatgt acctacataa tactttttgg
     6061 aaaatgatgg tgttgagaat gtaagtacat ttcaatgtga aattctaata tagccccaaa
     6121 cgaggtcaat aaaaatgacc taaactcgta tttctcccct aaacgaggag gagatagata
     6181 tgaaaattga atgtgccggc gttggagttg gctgctttta gtaggaatga acatggttcg
     6241 atgagaactg tttcagatag agtggtcgat gatcacaggc ctttaagtcg tttacagatg
     6301 atgagacttg taaaaataga gggacgaatg gaaaaagatg attggtatag aagaaaagaa
     6361 aggtgttcag aaagacgtaa caattgatag ggaagagaat cttaggggac atagattcta
     6421 ttggattgga cgcagagcac aagatatctt cttctcggct ctagctttga ttgcattgag
     6481 ccctgtgatg ctaattacag cgctcgccat tgtgattgac gatcccggtg gcagcccgat
     6541 ttttgtgcag gatagagttg gaagaaatgg aaagctgttc aagttttata aattccgatc
     6601 tatgtgtgta gatgctgaag caaaattaga agccttgttg gcacaaaacg agatggatgg
     6661 tccggtcttc aagattaaag atgacccaag aatcacgaga gttggtaaat ttattcgaaa
     6721 gacaagtatc gatgagttac ctcagctctg gaacattctt aaaggtgata tgagtattat
     6781 tggacccaga cctgctttac cgagagaggt ggaacaatac ggtgactacg aaaggcagcg
     6841 gttgttcgta cagcctggtc ttagttgcta ttggcagatt gctccacatc gtaatgaact
     6901 gtcctttgaa gaatgggtgg aacttgatgt gaagtacatc aatgaaagaa gctttatcac
     6961 ggactggaag attatcttct tgactttaca ggctgtatta tttggatatg gtgaatgatt
     7021 atatatagta ttaggagttg aaatatgtga atattatttt attatcgggt ggtagcggta
     7081 ggcggttatg gccgctgtcc aacgatattc gtagcaaaca attcatcaaa ctgtttaagg
     7141 atgaaaatgg cgaatatgaa tctatgattc aaagagttta tcgccagatt acaactgttg
     7201 acccagatgc aaaggtcact attgcaacaa gtaagtctca ggctagtgca atccataatc
     7261 agttgggaga taaggcttcg atttgtgtag aaccttgtcg tagagatact ttccctgcaa
     7321 ttttgttagc tgcagcatat cttcacgatg aacttggcgt aggtgatgat gaaagtgttg
     7381 cggtttgtcc tgttgatcct tatgtagata attcctatta cgaaggcgtt gaagcccttg
     7441 agaagttggt gcagcagaat acggctaatt tgactttgat gggtattgca cctacatatc
     7501 ctagtgaaaa gtacggttat atcatccctg aaagttctaa cgaagtaagt actgttaagg
     7561 agtttaagga aaaacctgac aaagcaacgg cagagaaata tttagctcag aatgctgttt
     7621 ggaatgccgg tgtatttgcg ttcaaacttg gttacctgtt ggaaaaagct cacgcaatgg
     7681 tggattttga agattatcgt gatttgtatt ccaagtatga gactttaacc aagatcagct
     7741 ttgactatgc tgtggtcgaa aaagaaacga gcattcaagt gatgcgttat aacggggatt
     7801 ggaaagatgt cggaacttgg aacatgatgg ctgaagttat ggctgataat attaagggga
     7861 aagctgtaat ggatgatacc tgtgttaata ctcagattgt gaatgagttg aatattccta
     7921 ttcttgctat gggctgcaaa gatatggtaa ttgcagcaag tggcgatgga attctgattt
     7981 ctgataaaga gcgcagtggc tatatgaagc cgtatgttga gaaaatcagt acggaagtaa
     8041 tgtttgcaga aaaatcctgg ggtacatata ccgttatgga cgttcaggaa ggctccatga
     8101 ctgttaaagt ttctatgcag gccggacaga agttgagcta ccactaccac aattctcgcg
     8161 atgaagtttg gactgttgta gcaggacagg gtaaagcgat tgtagatggt atgaagcaga
     8221 ttcttcgtgc gggtgatgtg gtgactattg ccgcaggatg taaacataca atcgaagccg
     8281 tgacaaatct ggatattatc gaagttcaga ttggtgaaac tattagcgtc gctgacaagt
     8341 ataagagttc tttgaactaa aagttcgcga ggtagttatt atggagatac taaaatttca
     8401 acccgtgggt aaagattatc tttggggtgg agaacggttt aagacggaat ttggaaaaaa
     8461 ttgacttaac accattaagc ttatacgtgg gaatgcttag ttcatctaga cgataactac
     8521 gtacggaaat atcaaatatg aaggacagaa tggtaaaacc gagttgtggt atgtattgga
     8581 agctacaccg gggggtgatt tatgcttttg agtacgatgt aacagaagaa atgttacgaa
     8641 atgctgtgat ggacagatca cttgggaaac atttatataa agaagaagta cacaagggag
     8701 atctttttta tgtcagttca tggtattggc gctggagtat tagtggctga aatacaggaa
     8761 agctcaaatg ttacctatcg agtttacgat tatgatcgag tagataagaa tgataataag
     8821 tgagaattgt actttgaaaa agcgattcag gtaatgaata tggaagccac tttgaaattg
     8881 gagaaaagaa ataagctcat tcatttttat cctggtggct ctcgtgaaat actgtgtaga
     8941 tgtaaatact gtgagcccga aagaatccaa gtaaagacgg ggttttcgtt ctcggtaaaa
     9001 gaggaatctt ttcaagttct tttatgtata tcgggggacg gacaagttga gtcggcaaat
     9061 ggtgttatga aactcattag atttgtaaaa aagatattgt atgtttttgc caacgaatat
     9121 tggaagatgt taagtgttga gcgatgcgga cttactgaaa attagatggg gatagaggga
     9181 ggatatctaa tgtcacgaat gagatttatg aacacagaaa ttgacaatct tacaatgggt
     9241 gaagtattgg tagaggttga aaaaatgatt caagatagga gatgcggata tgttgtaact
     9301 ccgaatgtgg atcacattgt tcagttggaa acaggaaaag agttgcaaga tgtttataaa
     9361 aacgcatctt taattttgac ggatggtaaa ccattgattt ggatttcaaa gttttataag
     9421 acaccaataa aagaaaaaat atcgggatcc gatatatttt ctttactgtg caagatggct
     9481 gcagaaaagg gatacacaat gtatttttta ggtgcggcag agggcgttgc ggctaaagcg
     9541 gcagataacc tgatgaaaag atttccggga ttaaatgttg taggaacata ctctcctcct
     9601 tatgggttcg aaaaagacga agatgaaatg tttaaaattg attcccaaat taaacgagca
     9661 aatccagata tgcttattgt gggtttgggt tgccctaaac aggaaaaatt tatgttttat
     9721 aactgtgata gattgggagt acctgtgtct tttggtctag gagctagttt ggactttgag
     9781 gcagggaatg ttaaaagagc accaaaatgg atgtcagatt atggatttga gtggctgttt
     9841 agaattactc aggaccctaa aagaatggca aaacgatatt tggttgatga tttaaaaatc
     9901 tttaaattag cactaaaata tcggaaaaaa taaactatat tcaatgagga caatgaagta
     9961 tgattattac aaaaacacct tttcgcatgt ctttttttgg cggcggaacg gatatggaag
    10021 attattttcg agaaaatggc ggtgcagtgc tttccactac ttttgataag tactgttatg
    10081 tgaatgtgcg tcatttgcct agattttttg attacagcac agagttatca tattctcgta
    10141 ctgagagagt aacaaatatt gaagatatcg agcatcctgc aattcgtaat gcgatgaaaa
    10201 tgctagatat gcatgaaatt cgccttacat atgaagcaga tcttcctgca cgttctggtc
    10261 tgggtacatc tagttctttt gccgtaggta tgttgaatgc tttctatgct ttgaagggca
    10321 agtacgctga caagaagaaa ctcgttgata aagcaattta tcttgaaaga gtcctttgta
    10381 atgaagcagg cggatggcaa gatcagattg cagcagctta tggtggcttt aaccgaatca
    10441 atttcaactc agatggctat gaagtattgc ctattattat tacgcctgag cgtaaaaagc
    10501 agcttaacaa caacttgatg atgttcttta ctggattcac cagattttcc tctgatgttc
    10561 agaaggcaaa taatgtcagc ggcacagagg acaaaagagt aagactgaaa aaaatgtatg
    10621 agcttgtgga tgaagcagaa gcggttctga ctgataagaa cagagatcta gatgatttcg
    10681 gcagactgct tgatctcact tggagattga aaaaggctac cggtggtgcg attagcactg
    10741 gaagtatcga tgaactttat gaaaagggca tggctgctgg tgcattgggc ggtaaacttc
    10801 tcggagcagg tggcggcggt ttcttggttt tttatgttca gcctgaaaaa caaaatgctg
    10861 tgcgttcggc aatgagtaat ttgatgtata ttccgtttga atttgaaaac ggtggaacac
    10921 aggttattca ttacacaccg gaaatgtata ttccaaaata aagaaatcag cgaggataag
    10981 aatatgaaag ttgttattat ggcaggcggt aagggaactc gcatctcatc ggttgcaagc
    11041 gatattccaa agcccatgat taaaattgaa aacaaaccgg tattggagca cgaaatcgaa
    11101 tgtctgagag accagggatt cacagatatt attcttaccg ttagccatct tggcgatatc
    11161 attatgaact attttggcga tggttctgga atttcaccag ttactggtca gccctttgac
    11221 gttaaaattg aatacttttt ggagaaagag ccattaggaa atgccggtgc attgtttcgt
    11281 ttaaaggata atttgaccga agacttcctc ctgctgaatg cagatgcgat gtttgacgtt
    11341 gatttcaacc gatttgtagc atatcaccgt gaaaagggtg gcttggtgac attgtttact
    11401 caccctaaca gtcatccata tgacagcggt ctaatcattg cagataagga tggctctgta
    11461 gacagatggc ttgtaaagga agattcccgt ccaacttatt accgtaacag agtaaatgcg
    11521 ggactccatg tgattagtcc tgctgttctt gatgtcgaga taaacacacc taagattgac
    11581 ttggaccgtc agttattaaa gccgttggca ggaaccggaa aaatgttctg ctatgatagt
    11641 ccagaatacg taaaagacat gggtacccct gatcgttatt atgctgtctg tgaagatttt
    11701 aaggctggaa gagtgaaggg caaaaatctt cagaataagc agaaagctgt tttccttgat
    11761 cgtgatggaa cgattaatca atatgttggc tttctgcgtc atattgatga gttcgaacta
    11821 atcaagggta ctgaagatgc agtgaaaaag atcaatgccg ctggatatct ggctattgta
    11881 ataacgaatc agccagtaat tgcaagaggt gaagtttctt ttgaagaatt ggaagagatc
    11941 cataacaaaa tggagacact tcttggatat aagggcgctt atttggatgc agtttattat
    12001 tgcccgcatc atccacataa gggatatgag gaagagcgcc cagagctaaa attcgattgt
    12061 gaatgcagaa agccaaagcc cggaatgtta attcaggcag ctacggactt caacatagat
    12121 ttgagtcagt cttggatgat tggcgatggc gagaatgata ttaaagcggg ccaagccgcc
    12181 ggctgtaaga ctgcattggt tggcgagagt gagtatggac aggatatgac catagcaacc
    12241 ctgagtgaat ttgcagataa gatctgctaa gggatgtttt atcacgaaag gagagtataa
    12301 acaatgatag acaatagatt acagaaacac attgatttgc tgattaaacg ctatcccact
    12361 cttgaagtaa tcaagcagga tattgttgac ggatacctga ttatggagga atgctattta
    12421 aatgatggca agctgctgat agcaggaaat ggcggatctg ctgctgattc cgagcatatt
    12481 gcgggtgagc tgatgaaaag ctttaagacg cctcgccctg ttagtaggga atttgcagat
    12541 aaattgattg cggttgatcc tgtaaagggt tctgaattag ctaagaatct tgaatatggt
    12601 ttgatggcga ttcctctcgt tgctcatgaa gcgctttcca ctgcgtatat taatgatgtt
    12661 gatggcctag gtgttttcgc acagcagttg tttggatttg gaagacctgg cgatgtattc
    12721 cttggtattt cgacatccgg caatagcaaa aatgtgataa atgcaactgt tgttgctaga
    12781 gctcttggta tgaaagtaat tggcttaact ggagccaaag gtggagaact tgcaagggta
    12841 gcagatgttt gtgttaaagc tcctgaaaca gaaacatata tgattcagga gtaccatttg
    12901 ccaatttacc actgttggtg tctaatgttg gaagataaat tttttgggaa tagataaaat
    12961 atctaagccc atattgaaag gataaaatta tgaatgtact atttataaca actcaatttc
    13021 catatcctct agataatggc ggaaaaattg gtgcgtacaa cggtatcagt gttttatcta
    13081 gagactacga tgtgacggta ttgtctttca ccgaagaacc gcagtatgtt gaagaaggtg
    13141 tcagtttttt tcgagagaaa tttaatagtg taaaatttga aaatcctgtg atacatgatg
    13201 tacacataag aaataatcca atgaaattgg tagaagcttt agcaataggg tattgtctac
    13261 gccaacctta tatagtttca aagttttatg attcaaaaat gctgcagtta atagatgaaa
    13321 aattttctaa caatgcatat tgggatatca tttttattga ctatctgaat atgcaaagtt
    13381 atggtcaata catacgggag aagtataaaa cacaatttgg taagtatatc ttaaaagacc
    13441 acaacataga atatgattta gtcctacagg aagctgaatc aagtcgaggt ttaaaaaaga
    13501 agttgcttca gttagagtat aagcgtactc gaaagtatga agaggccgca gtaaataggg
    13561 ccgattattg ctttagtgtg tgtgatgcaa atacggaagt actgaaaaag attaatgaca
    13621 acagttatac gatgcttcca acttatgaaa tgcttacagg ggtgaaaaaa aatatagaga
    13681 agaacacgat cctatatttg ggtaaccttt cttggaaatc caatatgcaa ggattagttt
    13741 ggtttttaga gtcaatttat ccaaatattc aacaaagaat tccggatgta aaaatcacaa
    13801 ttgtcggtag cgggccagtt ggaacagatt ttagtaaata ttcaggcgtg gattatcgtg
    13861 ggtatgtaaa agatatttca cacatttatg acgatcaagc ggtgctaatt gtacctttgt
    13921 tagaaggtag tggtataaga ataaaaatat tagaagcgtt caataatgaa attgcagttg
    13981 tatctacatt agttgggtgt gatacgattg gcgcaaaaga tggaagtgag ttatttatag
    14041 cagataacga aaaagatttt gcaacggctg tagttagact gcttgaagac atgaatttga
    14101 atgaaaaagt aagaaagaat gcaaaattat tcttaaaaga aaaatactcc ttaacggcta
    14161 gacaagatga gtttagtgcg ataattaaca gctaatatat atataagctt atctgatgat
    14221 gatttatagg aggaaatata tggagatggc tgagagaaag gaaaagaaac ttggaaataa
    14281 gaatatcata ttattttaga aaactcctgt tattttatgt ttgtgtgatt gttgcggcta
    14341 tgagttacca ccttacaggc aattccaatg tagcgtcatt aattgctgta gtaggagtag
    14401 tttatgctat tgtaaaggcg tgtaataacg agtatctggc tatatgggtt atgtttgtat
    14461 taggttctga tatatggggg atagtgccat atattaacat tggtagtggt gtgttgcatt
    14521 ggtcagattt taatgttata gtagcgatat ttctctgctt gagattcatc aaagttaaag
    14581 ctaggagtag atacgggatt gtctatagtg taatgcttat atttattttg attgcatgtg
    14641 tgcaatcgca ttcaatctat ggacaagatg tacatacaac gctcttaaca gctagagaat
    14701 tgctagttgt aatatccttt tggccgatag taaaaatagt atattcagaa agaataacta
    14761 aaaatgaatt cattgattta gtgtgtaaat tcacaagatg gacaatgtgt atatattggt
    14821 ttgaatggat tcttgttaat atgggattca atataacctt tttacagaca ggtgcacgct
    14881 ggggtactag aatctatata gatccgatat ttatcatttt atatttcttt ataaatctat
    14941 atgcggttat atataaaaga gagggctata atagtacaaa taaaagtata tggaattgca
    15001 tttttagttt actgacattt gttataatct cgcaaggcag aagtggtata ttatatgtag
    15061 taataacctc ggttattatg cttttaattt cgcttaaacc atccaagatt attagatttg
    15121 gtatattagg aattgcctta attgcatgtc tagtgtctgt gacccaaatt agagaggtcg
    15181 ttatatcttc gtttgtagag tctcagagca gtgacacagg taatatcgca tatagaattg
    15241 ctgaacaaga ttattttgaa aataaattag aaggtcatga actatttgga gttggtatac
    15301 caaacaatca tgatgccaga gctgtagaat attcaggcaa aacaatagat tttgagtcta
    15361 aaaaatataa tccctattat cttgaggact taggcgcttt tgaaattcgt tatagatttg
    15421 gtataattgc atatgcgtta tatatagttg ctttagctat aagtattata gatgccggat
    15481 ttcgaagaga caaatcggtc gccgcatttg cgggtatggc attcatggtg tttatggcgc
    15541 ttaattttaa tttgctagcg tatattacag caagaccgtt cggatttatg atttctttaa
    15601 ttttgataga aatatcggca ttcaatgatg aattcatata tattgaatag gtaagggaga
    15661 gcacagatga atttagatcg attaaagaaa atagcaaata tgatttcacc aatcataaaa
    15721 gtgataaatg cgccgttagc gtattttagt gggaaatcag attatatgga gaagggaata
    15781 ttgtggccta ctgtaacaac ctactccaat aacagtagaa aagtgattca atatacaact
    15841 ttacctaaaa acgtagacaa catggctcaa atgcaatggg ctggggaaag ttttgaggac
    15901 atatgtatag ttcttcaagg tccagtatta gaagacggtg attttacact aaataccgtt
    15961 aaaatgtata ataaatacta tcctaaagta aaacttgtag tgtctacttg gataggatta
    16021 tctgaagaga cagaatgcaa gttgcgtgaa gctggtgcag atgttgtatt atgcaagaaa
    16081 cctgaaaaaa caggtgcgta caatattaat ctacaactta cttctgcata cgaaggcgta
    16141 aaaatggcgc aaaaactggg gtgtagttat gcgctgaaaa cgcgaactga tcaaagacta
    16201 tatgcaaatg atgtactaaa gtatttccaa acattattga atatttttcc atcttcggac
    16261 tgtaaagtag tgaatcagcg attaatattt acgacttatg gaaaatcatt tagatatctt
    16321 ccgtttaatt tatgtgattt tttggtatac ggagaaacta gtgaattatt aaaattatat
    16381 ggtattcaaa gagataaccg agcatcagac tttgggaaaa ttatttatac tgaggaaaaa
    16441 gagtttaata aaaagatatt tacactacta gaaggaaaac aaggtgtatc tccatatgat
    16501 gtttttccag attttgatgc actatataaa aaatatatgt ttgcagaata ctatattgtg
    16561 tataattatt tcctggaaaa tattgcaagt aatgaatctt atggtgactt aatggatgcc
    16621 tattatagtt atttaaagaa atatgcagtt gttgctgatt cagaaaaatt gttactatat
    16681 tggccgaaat atgttcaata taatgttaag ttcgaaaatg aacttgattt ctatgcgaag
    16741 ttggattcaa aaaaatggat ggatatttat gctaattata caccttttag tcagtgatta
    16801 tatggaaagg atgaggtgaa taatgaaaat cggaatagtg actattgtta atggggcaag
    16861 ttttggtaac agattacaaa attatgcgac tcaaaaagtg ttggaaaata acggctatac
    16921 agttgagaca attaataatt gttttgacaa agaaggtacc ctatccattg ttatcaaaaa
    16981 cgctatttat acattattta agtttatacc gcatttcaaa aagtcaaaaa gtatctggaa
    17041 aagaatgtat acattttatc aatgggacaa gcagtatata gattattctc atcgtaaaat
    17101 tgatgcatct aaaaaaaaca gctttgtgag tataaagaat gattatgact atttcttggt
    17161 tggtagcgat caaatttgga atccaaaata tgcagccaat aagggatttg aacttttatc
    17221 atttgttcca aatgaaaaaa gagtttcatt atcaaccagt ttgggagttc catctatacc
    17281 aagtgattta gaaaaattat atgtgacaga gtggaataag tttaaatcaa tatcggtacg
    17341 tgaaaatcaa gcggcaaaaa taattgagga cttgacaggc acaactgcgg ctgttcacat
    17401 tgacccaact ttaatgttgg agcgttcgga atgggaagcc tttcaaaaaa aaccagacaa
    17461 tattgatgaa aattacatct tgtcgttttt cttaactaat ccgcctaagg atactgttga
    17521 tgtattagat aaggtcgcta aagatttgaa aataggtgtt ctcaccttag atgcgtcttg
    17581 ggaatatttt caagatatta ctccgaatca ttttgtttat ttgatttcac atgcaagaat
    17641 gatttataca gattcattcc actgcacagt tttttcattg ctatttggaa aaccggttgt
    17701 ggtatttgac cgttttgata gtgaaaaaat gaattctagg ttaagtacat tgttaaataa
    17761 agtaaataaa gcacattttt gggtaggaaa aaaagctgat gaagcaatga ttcgtgcaat
    17821 agcatctgaa cctgaatatg acatagataa gctgatggta tcagagaggg aatgtgtaaa
    17881 agcttatctt aaagagtatt tacagtaaaa ttttgaaatg ggatgaaaat atggagcatt
    17941 taagtgattg ttttggtaaa atgaagattg ttacgacttc atgcgcaaga gaatatttta
    18001 aggatgattt ggataaatca gagtattcat gttttgttga ttctcgagca gctatgtttt
    18061 tcgcaatggg acaagcttta gctaaaagaa ggaatgtagt tgtaatgctt gctgatgaat
    18121 tgacatcgtg ttatacggca ctaacagaat gtgcatttca acaagttgat ttaattgtgt
    18181 ttgcttttca gacagtcaga catgaaattg atttagcatc tttgaagaat tgtggttgca
    18241 atctaattaa ctgtagcgcc caagacgata ttgatagagt tgtgtccaac actaaggggt
    18301 taaatcagac aacagtaatt aaaatcaata tgaattgtga gtcggataaa gatcatatat
    18361 gtgagtatat agacctgcca gacatacctg tttttttcca cggtagctta tactcacctg
    18421 caagtaaaaa gaaatatgag cagtatggac aggtatcgaa gtatttaggc tatctcgtgg
    18481 ggggaaaaga tgcaatactc ataatttctc acaatgagtt tttaaacgat atcagtgtat
    18541 ggattaatta ttattctttt ggagaaattc aacccaaaat tattatattt gacagtccga
    18601 atgactatca atataaatgg ctgtgtgact tagaatgcag tgtagctcat tcaaccaacc
    18661 gatttttgtc tgaggattta gccttattgc aaaataacgg aatttccatt gtgttaagag
    18721 gtgataatta tgatatcgtc agttaaaaat gttcaaattt tagtatcttt attaaaacag
    18781 cataatatta aagatatagt tatctcgcca ggtagtagag attttcaatt ggtgcatagt
    18841 gtagaaacag acagtttttt tagaacctat acggttgtag atgagcgcag tgctgccttt
    18901 tttgctaatg gactttctat ggcgattgat aagcccgtgt gtgtatgttg tacttcttca
    18961 actgcctctt caaattatat ggcggcagct aaagatgctt ttgctaatgg catccaactt
    19021 gtacttctta ctgctgatag agattaccgc cgcttatatc agatggaaga tcagatgatt
    19081 gatcaggtag atatgtatgg ggcttatgtg cgttctaacg ttgatattcc tattgttaag
    19141 gattctgatg atgaatggta tgctaccaga aaaataaatg aagcaatatt ggagttaaat
    19201 catggcgtta agggtcccgt gcagattaat tatcaattaa tggatttaag tgcgccgttt
    19261 gttgagacca tgccagagta tcgtaaaatt acaagatatc aagaggatga tttactgtca
    19321 tcagtagaga tttttaaaca gaaactatta tcaaaaaaga gaataatggt tttatgtgga
    19381 cagcaggaag aaaataattt aagtgcctta ttggaagagt tctttattaa atataataca
    19441 attataatca aggataacta ttctaatata cacggtgaac actttattaa gactgttcta
    19501 gtaacagaaa gaatgagtgt aaatgcattt attgattatt gcccagattt ggtaataact
    19561 attggtaaac atgtatggtc ttttgtgaaa tatactctta gagataaaaa gcttaaattt
    19621 gagcattggc ggatatctga ggatagtaag attgttgatc cgttcaacaa gctaacatct
    19681 gtctttcagt gctcagcgga attttttatg gagactgtca ctgctggtgt gaatagcaat
    19741 aataatcttg agtattataa tctatggaag acaagattat caaaagtttg ctatccagag
    19801 ttagtctata gcaattttta tgcaatttca gaactagtaa aaaaaattcc agatagtgca
    19861 ttagttcatt ctagtatttt aaatgcggct agattgtatg actttgtatc tgatgataaa
    19921 gcattactca gttttgctaa tttaggggct gatggtattg atggttgttt accaacattt
    19981 ttaggtcagg cagaagcaga taaaactcga cctgcgtatt taatttcagg agacttgagt
    20041 ttcttttatg ctatgaatag tttatgtggt gacattccag ataatgcaca tattttcctt
    20101 attaacaatc attctggaag tgaattccat acaaattttg gtaagtttta caacggatca
    20161 ttaagtgttg ataagcatat agctgcagga catatttcaa acgcaaagga ttgggcatta
    20221 gaaaataata taaaatacat tactgcggat tctaaggaaa gtctcaaatc ggggttggat
    20281 gtatttatta atacatttga cagtcctgtt ttatttgagg tctttacaga tccggatacg
    20341 gatacgtctg ttctggaatc tttttatagt ataaataagg taatcacacc aaaaatgtat
    20401 tttagaaagg cgttagatat tataaaaaag catttacaca ttaagtagat gtttattgcg
    20461 aggtgaaaca aatatggcaa taaaatctta tattaaacgg ttattgcttt atatccgtca
    20521 tggagatccc aaaataaatt tagatgtgag ttatttatct gaaggtgcaa tgcttgctgg
    20581 taagactgtg ataattacgg gtggtgcaaa aggacttggt tttgcaattg caaaatcatt
    20641 tatagctcaa ggcgcaagcg ttattattac aggaagagac atggattcgt tgaataatgc
    20701 taaatgtcag cttggagata tgtgttctat cagggcgttt gatataactg atgctaaaat
    20761 gtatcgaacg ttttttgaag atgcatacga gacctttgga cgtattgata tactgcttaa
    20821 taatgctggg atctcgttac acgaagatgg atttatgagt gttactgaga aaacttggga
    20881 taagcaaatg gatacaaatt tgaaaggtgt ttatttcttt acacaggaat ttattaagtt
    20941 tgttaaagaa aagaatcaaa tgcaagcaaa tattattatg atgtcctcag aaagaggctt
    21001 gtgtggtgat agtattccgt atggattatc aaaggctgca attaactctt tagttgtagg
    21061 cttgtctaag aaatatattt ctgagggaat tagggttaat ggtattgctc ctggagtaac
    21121 tgcaaccgct atgactggta tttctgaaaa gggtaatttg tataatcctg caacgatcgg
    21181 ttatagatat tttctcccag aagaagttgc tcaagttgct ttgtttttgg caagtagtct
    21241 ttcaaactgt atcagtggtg aaatcatagc ctgtgaccag gggcaatatt taagtcgaaa
    21301 ttgggggtaa taacttggga atattattaa aaaaatataa tagccttagt gagcctgcaa
    21361 aagcatctat ttggtttaca ctttgtaatg tgttgcaaaa aggaattcta tttttgacta
    21421 cacctatttt tacaagaatg ctttcaactg cagaatatgg taagtatacg atttttatat
    21481 cgtggtattc tattatagca attttcacaa cgttgaattt atctgcaggt gtctataata
    21541 aaggactaat taaatacgag aataaatatg cattaacctc gtcattttta ggattatcgt
    21601 catttatttc cctttgtgca ttgatgctat accttccatt tagaacggtt ataaatgggc
    21661 tactggattt atcgacggag tttgtcatat tgattcttat tgaatcaata tttgagccgg
    21721 cttttttgct ttggtcagtt aaggaacgat ttgattacaa gtatcaaaaa ctagtactca
    21781 tcacagttct tatggctgtt ttaaatccag gtctcggtat tatattaatc ttatcatttg
    21841 gggagtatgc tatttggaga gtacgagctt atgtcgtggt aaatgttgta gtggggatgt
    21901 ttattggcat aggaatactg gctaagggta agaaattatt tgataaagag tactggacat
    21961 atgcgctcag atttaatttg ccattaatac cacattattt atcaatgaca ttgctgaatc
    22021 aggttgatcg ccttatgata aatagtatgg ttggagctag cgaggctgcg atttatagta
    22081 tcgcttacac tatatctagt atgatgaata tcataacaac agctataaac ggttctttta
    22141 ttccttttac atacaaagca attaaagatg gcgtgtatga aaaaattaaa tccgttgcta
    22201 atcaactatt agtgttgatt tttgtcttgt gttcgtttac tatgctgttc gggccagaat
    22261 tgatttgggt tgtcggagga gaaaaatata tggatgctgt ttggattatt cctccagttg
    22321 cggcatcagt atttttcatg tttttatatc cgctttttgg caatattgaa ttttactatg
    22381 aaaagacaaa ctacgtaatg tttgcatctt gtgtgggctc tatcgcaaaa attatttcaa
    22441 actatgttag tattccccgt tttggatata tttcggctgg ttacacgaca ttgatttgct
    22501 atatgttgtt ttcctttgcc cactacatgt tttataaaaa aattcttaga gaaaatggta
    22561 taaaagaaga tatgtataat attaaaaata ttatatttct ttctgtctta atgattgtgt
    22621 taactattgg tatgacaata ttatactttt ctacaattct aagatatagt attattattg
    22681 gattagttat tgtggctttt cttaaaagga cgcaaataat gaaaatcctt aaaaatataa
    22741 aaaattaaca agcaaatctt gggaatggaa cggaggcacg gtgaaatgag attattgatt
    22801 ccatctgcta agattgtacc ggaagaactt caccatcttg gaaaacttcc tgcaattatc
    22861 tatccgatta atcaaaaaat tgtatttgat tatttatatg atcaatataa agatgtatgt
    22921 tctgctatcg atattgcctg ttacgaaaag atggataagg tagcaagacg attagataag
    22981 tatattaaat ctaaaacagt aaatattatt cagcttaaag agttagggga tcttggaaga
    23041 actatatatg attctctaat aggatgtgac gagcctgtta ttattaattt tgctgatacc
    23101 attatcaatg ataatatata ttccttggaa tgtgacagct ttttctatgc tgaagactat
    23161 tatagtaata cttggacatt ctttgaagaa aaagacggag atattatttc tgttttagat
    23221 aagaacgagt taaaagaaga tgatggaaag aagcacaaac tgttttctgg tgtatttcaa
    23281 attatggatg cccagtattt tagagagtgt ttgcgtaaag ctttgatgtc aaatgtagta
    23341 aatgtgaata gtttttatca agctttacaa gagtatagca aacgatatga atttctctct
    23401 attaaaacaa ataattggtt tgacattgga catgcagata aatattataa ttccaaattg
    23461 gaagttaagg caagagaatt taaccacatt tcaattgata aagatcgtag catcctgaga
    23521 aaaattagtg aagatgttga aaaatttatc ggagaaatta agtggtatct taagttgcca
    23581 gcacaggtag aatatgtgag acctagaata ttcgaatatt ctacttcgta tattaatcca
    23641 tatgtaagta tggaatacta ttcgtatcat actgttcacg agttatttct ctatagtgac
    23701 ttaacaaaaa aacaatggat agatatcttt aatagaatac gatttgtatg ctcagacttt
    23761 aagagatact ctgtttcagg ggataatatt caaaagtcat tgaaagatat gtatctcgat
    23821 aaaacatttc agagattcaa taagctcaga aaggaccccc ggttcacaga attcttttct
    23881 tctgatattc aaataaatgg agtcagatat aaatctttgg accagataga agctttattg
    23941 agcgtaagtg ttccaagaga attgtttgac attacgcaat ttaatattat tcatggtgac
    24001 ttatgctttg ccaatattat ggtagataac acattttcgt tcattaaagt catagatccg
    24061 cgaggtaagt ttggagattt tgatatttat ggtgattata gatatgaact ggcaaaattg
    24121 tttcatagtg ttgatggaaa atatgacttt ataattaagg acttgtttac aataaaatat
    24181 gatccaaaga aggcaatcat agactatatt gttcaagatc gtaaacgaga ttatgattta
    24241 tatgaagtat tttactctgt cttcaaagat gaaataggtt ctgatttgaa aaaaattgaa
    24301 cttattgagg ctttgctgtt tttaagtatg attcctttgc atggagaaag cttaaaccat
    24361 cagatggcta tgttagcaac tggtttggaa attttaggac gagttgtccc ggatatttat
    24421 tgttaatgct ttgagctatt gtttttctat ttgatcagtg taaagccggg catataaatt
    24481 gcctggctaa aataaaggag atgtcttagt tatatgttta aagattacgc atttgttttt
    24541 gatattgatg gaactttgtg ccccatcaaa aagaaagatg agaaatatga agatttagtt
    24601 ccgtatgcta atatggtgga gaagttgcga tactataagg agaacggagc aaagattaca
    24661 ctgttcacat ctcgcaatat gaattcttat catggtaatt taggtgtgat caatgcaaat
    24721 actgcaaaaa tcttgttggc ttggctagat aagtgggaga ttccgtatga tgaaattctt
    24781 tatggaaagc cttggccagg ccataaaggg ttttatgttg atgatcgcac agttcgtccg
    24841 gatgaatttt tatcgtgtac cctggatcag ctcgatgaga tttgcaaaaa atccaaattg
    24901 aaatctgagt aaaggagact ttataaagtg aataagatga cggttattat tacaatggct
    24961 ggtcttggca gtcgctttcg taaagttggc tacactgtgc ccaaatttat gattgaagca
    25021 aaaggtaaaa ccttatttga ttggtcctta gacagcttgc ttgattataa ttcacatgta
    25081 gaaaagtatg tttttgttgt gcgtaaggaa gatgatgcta ctgtttttat caaagaacat
    25141 tgcagtctgt atggaattga aaatgtcgag gtagttgaaa ttgactatat gactgatgga
    25201 caagccacta catgtatgct tgcaattcct tattgcgcac ctgataatgc aattatggtt
    25261 tataacatag atacatatgt tgagccaggt gagatgaaat acgttgatat ttctggagaa
    25321 ggacatattc cgtgtttcca tgcggacggt gatcattgga gttttgccaa gttgaacgaa
    25381 tatggtgatg tagtagaagt aagagaaaaa gttagaattt ctaacaattg tactttaggt
    25441 gcatattatt tttcttctgc aaaattatat gcatcactct acgaagaata ttatgcagat
    25501 gaaaggcatc tggaaaagaa tgagaaatat attgcgccgc tatataatta tatgatagag
    25561 aagggcatga aggtaaccat tagtatagta gataaatcaa aagttcacgt actcggtact
    25621 ccagaagagc tcgatgtgtt cttaaatgaa tagggaaaat ataatcatag aaaatgttaa
    25681 ttataaagct gcgtgtgtgg gggagtacta ttcgatagat attctaaaaa tactaatggc
    25741 tattttagtt gttgttcgtc atttaggtca aaactattta gctccagatt aagcatttag
    25801 tattggtatt gttgcaggac tgagtacggt tgccgttcct acttttttca tcatcagttc
    25861 ctttttgttg tgtagtggtg aagttacatc cgctaaatta tctaaacaaa tctacagagt
    25921 acttaaaatt tacattattt ggtctatatt atatattcca ttagtattaa agaattgggt
    25981 acagtcagat tttagctgga aaacagatgt attattgtat atcagagatt ttctgtttat
    26041 tggtagttac tatcacctgt ggttcttgcc tgcactggct tttgctctat ggttagtacg
    26101 caaaagccag gtttctaaaa taaagtttct cagtggtttg ttgctatgcg tagtaggttt
    26161 agcatttgaa tcttattggt ttatattatc tgggaatgat tccatcgagt atattagata
    26221 ttgttataaa agcgtgtttg taacaactcg taatggatta tttataggtg taccatgcgt
    26281 cattattggg caacacttag ccttccacaa aaacactata cttaataagg tctttaaata
    26341 ccgtaatttt atcttatgtg ctgttttagc tataggatgc ttattagttg gtgaaagttt
    26401 catcataaat caaatagctt tgcgagaagt caataatttg ttaatatttt ccattccatt
    26461 agcactggta gttgtatcag tatcactgag cctaaagata gtacatttat aaaaataaca
    26521 gtacatctgc gaagaattag tacgttatta ttttgtttac atccgtatat aatagctgct
    26581 ttaaatttta ttttcccaaa attggggatt acaaattcat taatagaaat gacttgtgga
    26641 atgataataa ttttaatttc tacagttttt gtgtatgcgt gtagtgtgaa atttaccttg
    26701 ctgaaaaaat tatattagat tagtaactgg tacatgtaaa tttgttgaaa ttatagcagc
    26761 atagagatag gaattctgtt gagttttatt ttcgctggcc gaggttattc atgttagagt
    26821 gggtacctcc ttttacgaaa ccttcttgat ggtactcatt tagcgcatga tgaaaggaga
    26881 gtttatgaag aaaatcatat cttctatttt ggttaatgtg ttatctgcat tgtatcaaat
    26941 atttgggttt cgattttaat tgcagttttg gctatgtttt tatacttgtt tgcgatggct
    27001 gaggagaaat caggattagg tttgaaaaaa tcttttcttg tctggattcg gtatttcaga
    27061 aaatcaagct catttagaaa aatgtttttg cttgtgtttt ttacaaatat gattcttttt
    27121 agaacactga tggatagata tgtttggcta aatcctttgt ctaatgtgtt tggtagttgg
    27181 tggatttact ctgtgaatga aacgacaggg gagattagat taactacaga atgttttgaa
    27241 aatgttattc tgtttattcc atttataatt ctagtaatgt ggtataaggc ttcagaaaaa
    27301 gattttggaa aaatttatca gagattataa aatttgtttt tttatgttcg tgtcttatag
    27361 agtttttgca gttattttta cacatagaga cattccaatt gtcagattta ttttataata
    27421 ctttgggtgg cggcattagt ggggttatat attatttgag ctgatatatt catcctaacc
    27481 ttaaaaataa atgagcagaa ttttaaaaga ttggagagat tctatggatc ataatgcaaa
    27541 ttattatcat tggcttacaa atgccaatgc agaaattgta gaggaactgc ggtcatattc
    27601 cgagaaggac attgaggact ccttctataa aaatctgtcc tttggtaccg gtggtctgcg
    27661 tggcaccatt ggtgcaggca ctaatcgtat gaacgtacac accgtaggta aggcaagcca
    27721 gggactgtca gactatctga ataagaccta tgaaacccct tctgtcgtcg tgggctatga
    27781 ttcccgaatc aagtccgatg tatttgcaaa ggttgccgcg gacatctttg ctgcaaacgg
    27841 tattcaggtg catctgtggc cggagctgct gcctgtgcct accgtatcct ttgctatccg
    27901 ttatctgaag gcttctgccg gtgttatgat caccgcatcc cataatcctt ccaagtataa
    27961 cggatataag gtctatggcg caggcggctg ccagatcacc accgaggctg ccgctgagat
    28021 tctggctgaa attgaaaagc tggatatttt tgcagatgtg aaaatgggcg gcgacgcttc
    28081 cagaatcgct tctatccagc cagaggttct gactgctttc attgaagaag taaagggcca
    28141 gtcggttctg tttggcgaag aagtggacaa gaatgttgct atcgtgtatt ctcctttgaa
    28201 tggtaccggt ctggtgcctg ttacccgtac tctggcagaa atgggctaca gcaatgtgac
    28261 cgttgtcgaa gagcagcgtc tgccagacgg taatttcccg acctgtcctt atccgaatcc
    28321 ggaaattaat gaagctatgt ctctgggcat ggagtatgcc aagaagtata atgctgatct
    28381 gctgctagct accgaccctg actgcgaccg tgtgggtatc gccgtgaaga atgcagaagg
    28441 ggattatgtc ctgctgtccg gtaacgaaac tggtctgttg cttctggact acatatgctc
    28501 tcagagaatt aagcacggca agatgcccac tgaccctgtg atggtcaaga ccatcgtgac
    28561 tatggatctg ggcgagcgga tcgcttccaa ctatggcgtg cgtactgtcg atgtgttgac
    28621 cggcttcaag ttcatcggcg aacagattgg tatgctggaa aaggcaggca aggtggacag
    28681 ctatattttc ggctttgagg aatcctacgg ctatctatcc ggcagctatg tccgtgacaa
    28741 ggatggtgtc aacgccgctt atctgatctg cgagatgttc tcttactaca agactcaggg
    28801 tatcagtctg tttgataagc tgaacgagat ttatgctaag tatggctact gtttgaacac
    28861 cctgcattcc tttgagtttg agggtgcggc aggttttacc aagatgcaga aaattatggt
    28921 tgaattccat aaaggtcttg atatgattgg aggtaagaag gtcattgaaa ccttggatta
    28981 cagcacggga ctgaatggcc tgccgaagtc tgatgttctc aaatatctgc tggagggcaa
    29041 ctgctctgta gtggttcggc cttccggcac tgagccgaag ctgaagacct atatcagcgt
    29101 tagcgcagaa agcaaggaag ctgccgaagt aatggaagct gttatggctg ctgaactggc
    29161 tgaaatgttt aagtaatact atgaaaaaga tctgagtgtc aatgtccgaa gtagcaacat
    29221 ctatgtttaa taaaaatttc ctgctttacg gttctgttta cataattgag gtaaaggggc
    29281 cgactgtgtg gatcgaaaag gcaaagaagt gttaacagag acacagcagc ctgatgaagc
    29341 accgatcaaa gcagtaaggg agaaataaga gatattagag ttttaataat gtattcagca
    29401 atagagatga aaggagtaga atatgaataa aactattgaa ataataaaat gagggggaaa
    29461 gaaataaacg tgatattatt agttttgaga aggcgttttc aatattcgct attgtattga
    29521 tgtactattt tcagcaatcg tatttgccag caatactgaa caaagcaata tctattggtg
    29581 atacaggagt gcatatattc ttcttttgct caggttttgg gctatatctg tcatatttaa
    29641 aaaagcctat tacattgggt gaatttttac agaaacgatt tatcaagatt tatattccgt
    29701 atattatcgt aattacggta tcagtgttac taccttatat gacacaagat ttaaatgctg
    29761 caaaagtata tttgtctcat gttttgttat ttaaaatttt tctaccagta tatgaggagt
    29821 cactgggtcc ctttggttta tttcgacaat tattcagttc tatttcttat tcataccaat
    29881 tgtaaaacta tagagaaaaa taggaatgaa atgattgctt gttgcaagct gagttattag
    29941 tatctgggct attatgatgt ttcatacagg atatggaagc atacgagttc ttgggagctg
    30001 ctttgcgcaa tatatttggg aatttacttt cggcatgttt ggttgcagag tatttagtga
    30061 aaagaaaaat agtaagattt aataatatat tcgtgattat ggcgtccatt gttggaattg
    30121 gttttgctgg tatatcgaaa attattggtg gactgatgga gtctattaat gatatttttg
    30181 cattcttcgg ttacggtgca attgcaattt taatgtatca agttattcca tttagaaaga
    30241 taatgcctag gatttcaaga tactcatatg atatatatct actccatatt cttgtattta
    30301 gtacgattca tcaaattatc cctaacttgg ttttggcggc atttgtttcc attcctataa
    30361 cgttggtgtt gtcatattat tatagtatta tgttatatag acttaaatta aaatgatagc
    30421 ataattgtcg cctctaccgg gcggttgcca tcctgattaa cagcctccac gcggcggatg
    30481 gtgggcactt aggtagttcg taacctagtg gtagatggtt ggtaaaaagg agataaaact
    30541 aaatgattac acccgtggtg ctagttaatt ttaatatcct aaagaatatc tcaaagttcc
    30601 ttcaaaacgt cgttgtgctc gacttaatag aacactgtaa gccagtaata tgctttcaaa
    30661 tctactctct agccctttaa cagaacgtga gttgaaattt tgacaaccta atttttct
//
LOCUS       DARPZF010000028        29154 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.029, whole genome shotgun sequence.
ACCESSION   DARPZF010000028 DARPZF010000000
VERSION     DARPZF010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.029"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..1030)
                     /locus_tag="SLE65_001644"
     CDS             complement(<1..1030)
                     /locus_tag="SLE65_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8448939.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="SLE65_001645"
     CDS             complement(1112..1801)
                     /locus_tag="SLE65_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEI8448940.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="SLE65_001646"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="SLE65_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEI8448941.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="SLE65_001647"
     CDS             complement(2328..2831)
                     /locus_tag="SLE65_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEI8448942.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="SLE65_001648"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="SLE65_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEI8448943.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="SLE65_001649"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="SLE65_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEI8448944.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="SLE65_001650"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="SLE65_001650"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEI8448945.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="SLE65_001651"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="SLE65_001651"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEI8448946.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="SLE65_001652"
     CDS             complement(6443..7462)
                     /locus_tag="SLE65_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HEI8448947.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8540)
                     /locus_tag="SLE65_001653"
     CDS             complement(7635..8540)
                     /locus_tag="SLE65_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEI8448948.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="SLE65_001654"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="SLE65_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEI8448949.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="SLE65_001655"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="SLE65_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEI8448950.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="SLE65_001656"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="SLE65_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEI8448951.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="SLE65_001657"
     CDS             9753..10397
                     /locus_tag="SLE65_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEI8448952.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="SLE65_001658"
     CDS             complement(10453..10956)
                     /locus_tag="SLE65_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEI8448953.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="SLE65_001659"
     CDS             11553..12518
                     /locus_tag="SLE65_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEI8448954.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="SLE65_001660"
     CDS             complement(12617..13789)
                     /locus_tag="SLE65_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8448955.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="SLE65_001661"
     CDS             complement(13776..14921)
                     /locus_tag="SLE65_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8448956.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="SLE65_001662"
     CDS             complement(14935..15867)
                     /locus_tag="SLE65_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8448957.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="SLE65_001663"
     CDS             15984..17063
                     /locus_tag="SLE65_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEI8448958.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17689
                     /locus_tag="SLE65_001664"
     CDS             17060..17689
                     /locus_tag="SLE65_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8448959.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17799..18026)
                     /locus_tag="SLE65_001665"
     CDS             complement(17799..18026)
                     /locus_tag="SLE65_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEI8448960.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18129..20717)
                     /locus_tag="SLE65_001666"
     CDS             complement(18129..20717)
                     /locus_tag="SLE65_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEI8448961.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20737..21396)
                     /locus_tag="SLE65_001667"
     CDS             complement(20737..21396)
                     /locus_tag="SLE65_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEI8448962.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="SLE65_001668"
     CDS             complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="SLE65_001668"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HEI8448963.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22169..23035)
                     /locus_tag="SLE65_001669"
     CDS             complement(22169..23035)
                     /locus_tag="SLE65_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEI8448964.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23144..23785
                     /locus_tag="SLE65_001670"
     CDS             23144..23785
                     /locus_tag="SLE65_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEI8448965.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="SLE65_001671"
     CDS             complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="SLE65_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HEI8448966.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25226..26125)
                     /locus_tag="SLE65_001672"
     CDS             complement(25226..26125)
                     /locus_tag="SLE65_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEI8448967.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26127..26924)
                     /locus_tag="SLE65_001673"
     CDS             complement(26127..26924)
                     /locus_tag="SLE65_001673"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEI8448968.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26902..27606)
                     /locus_tag="SLE65_001674"
     CDS             complement(26902..27606)
                     /locus_tag="SLE65_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEI8448969.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27737..28312
                     /locus_tag="SLE65_001675"
     CDS             27737..28312
                     /locus_tag="SLE65_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEI8448970.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28430..29107
                     /locus_tag="SLE65_001676"
     CDS             28430..29107
                     /locus_tag="SLE65_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HEI8448971.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8582 a         6173 c         5242 g         9157 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga
    17221 catccgcatg cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc
    17281 caaagccatc cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt
    17341 ttccatcggt gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt
    17401 caaatccgct tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca
    17461 aatgatgaag aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga
    17521 gcttgcaatc atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt
    17581 gtacttgagt gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt
    17641 acgggatcgc acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa
    17701 cacaaaaaaa cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt
    17761 caattgtccc gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca
    17821 ggattcgttg gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt
    17881 tctagttttg attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat
    17941 tctttttcca tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct
    18001 aatttatctt cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca
    18061 tatcacactg aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat
    18121 ctttaaaatc aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca
    18181 atcatcggat ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa
    18241 acagcaggtt ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt
    18301 tccactgttt ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt
    18361 agcttttctt ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt
    18421 ccgaccaaag aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca
    18481 ttatccatga tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa
    18541 gtgacatagg cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc
    18601 gtgtagagca aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc
    18661 atcttgaatt cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta
    18721 ttccattcgt ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc
    18781 actttatctt cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg
    18841 aatacattca attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg
    18901 gtgtcgttcc aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc
    18961 attttattta acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata
    19021 tcttgtgcac ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca
    19081 atttgataag catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt
    19141 ggcagacgtc cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc
    19201 cgataaatct gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt
    19261 acttgaccag gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata
    19321 ttcgtcggaa tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca
    19381 tcaacaatca aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt
    19441 ccattcagcc ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt
    19501 cgtttagctg ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat
    19561 tttgaaggat ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc
    19621 acagtagttt tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct
    19681 tcagcgatag cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc
    19741 cgaatattct tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg
    19801 cgctggatcg aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta
    19861 gtctcttctt gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga
    19921 tcaggctgga tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat
    19981 gtctccgccg gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag
    20041 atagctgctc gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta
    20101 tctgcacgtt tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg
    20161 atgatatcca aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg
    20221 aacccgtaac gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc
    20281 tcagcaagca tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga
    20341 tcagcaatga ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt
    20401 ttcttcccga ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt
    20461 gttggctttt cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc
    20521 actaattctc cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg
    20581 actacaatct ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact
    20641 ttgtaaaaat tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc
    20701 atttcttctg gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt
    20761 ttcagttcct aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca
    20821 aggctcttca gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa
    20881 ctcacttagc tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc
    20941 tacgaataaa agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat
    21001 acgtgtgatt gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa
    21061 atgattacgc aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg
    21121 accttctaaa gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg
    21181 acgagcaagc tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga
    21241 ataaattgct ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta
    21301 actttgtggc aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca
    21361 ttgtgtcttc ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt
    21421 ttattttact ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa
    21481 ttctaaatta gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt
    21541 cgataaattc aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc
    21601 gttttcacgc ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg
    21661 ctcttctcca tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa
    21721 atgtagttta cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat
    21781 atttacatca ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa
    21841 acctagtggc tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt
    21901 tccagtgttt gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc
    21961 tctcatattt atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt
    22021 atcaactcgg tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt
    22081 tatcagaaca ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc
    22141 ctcaactttt ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag
    22201 ttccttttaa taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg
    22261 ctttgattcg ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat
    22321 tttcctctgg tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt
    22381 cagcaaactt ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat
    22441 aaaaagcctg acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc
    22501 catcttctga gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa
    22561 ccgcgttgaa tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg
    22621 cttcggcaga ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag
    22681 cattttgaat ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa
    22741 catctaatag cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat
    22801 acatgccaga ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt
    22861 taaccgcatg ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat
    22921 ttttgcatat caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga
    22981 acagctgatg attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc
    23041 cccctcattt ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg
    23101 atacaatgcc tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg
    23161 cgctgaaaac tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt
    23221 gtgtgacaac ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt
    23281 aagttatgct ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga
    23341 cttcgtctat aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa
    23401 attagggacg gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga
    23461 ggccttagaa ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt
    23521 tgacagtatt cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt
    23581 tgaccgtatc ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg
    23641 gcttaaagaa ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt
    23701 cactgcagag aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac
    23761 caaaatcgtg gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa
    23821 tgcttattgc aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata
    23881 ttgaaataaa tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct
    23941 actgctggat caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc
    24001 gccactgtga ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt
    24061 ttccaaaaac ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg
    24121 gtcaagactt cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca
    24181 agtcgacgaa cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc
    24241 agcgaaatga agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt
    24301 aaagaagcgg tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac
    24361 gctgccttta ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa
    24421 tcgctagcag cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac
    24481 aaatgatcat cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt
    24541 gccacatctt cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca
    24601 gaaatcattg cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc
    24661 tgaccttctt gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc
    24721 ttcagcacgt acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt
    24781 gtcatgatcg cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca
    24841 tcgtctgccg acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc
    24901 aagtcaacag cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc
    24961 atttcatcta ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc
    25021 gctaattctt taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat
    25081 tggtagaatt gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga
    25141 atattatttt cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt
    25201 tcatccaaac caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt
    25261 ctgcggctaa aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca
    25321 gatcataaca atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat
    25381 catcaccgag cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc
    25441 ctgtatgcag ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact
    25501 cagtctgtgc cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc
    25561 gggcgatcgg caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta
    25621 aggcctgata ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg
    25681 caaatccatg ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca
    25741 catggattac ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca
    25801 ttgtcccatt tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta
    25861 ccagaacgtg ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt
    25921 catgttctcc ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca
    25981 agacattttc tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta
    26041 acagaccctt tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt
    26101 tctcataatc ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga
    26161 tgccaaaaat gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa
    26221 taaattgagc ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct
    26281 tctgtatttt ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc
    26341 aaagtacgaa acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata
    26401 ctaggatgga tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta
    26461 gaaatcgtca atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg
    26521 gctaccatcg tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg
    26581 tccggtgttt catccaaata actgatccga acatccagca agggataact aacactttgt
    26641 tcccggttcg ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg
    26701 taaaacccta aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg
    26761 tagtgatgga acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc
    26821 tcatgatcat ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact
    26881 tctatagtct ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct
    26941 ttcgctttct ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg
    27001 ggagaataac cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa
    27061 ctgataggca gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc
    27121 ttgatattta taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg
    27181 aatctggatt tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat
    27241 caccagatga taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg
    27301 gagaactttc atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac
    27361 aaactgacac atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat
    27421 tggaatatgc cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt
    27481 gacaaattca atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag
    27541 tttcactttc aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg
    27601 ttccatagct gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa
    27661 gttttttcgt actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca
    27721 aaaaggagtc gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa
    27781 gcaagagtac gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca
    27841 gactaatatt tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg
    27901 gatccgtttc gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg
    27961 tctcgaaaca acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg
    28021 tctgcctcgt tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc
    28081 attaatccaa accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact
    28141 tttagctatt gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt
    28201 aggggatgca tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc
    28261 ttatcgtcct gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt
    28321 cattttcaca aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg
    28381 aaagaatcta gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat
    28441 ctatttattt gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca
    28501 atttatcgaa gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc
    28561 tttggtcaat ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa
    28621 tcttgaggaa cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc
    28681 ggcgcagttt caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt
    28741 cggctgtaat gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg
    28801 cggcgatttg aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt
    28861 ttctgatcaa aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta
    28921 caattatgcc tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct
    28981 ttggagaatc acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga
    29041 acatttacat acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc
    29101 taattaaaaa aggctctttg tcaaatgatg ttggtaaaga gaaatcttag aata
//
LOCUS       DARPZF010000029        28682 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.030, whole genome shotgun sequence.
ACCESSION   DARPZF010000029 DARPZF010000000
VERSION     DARPZF010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.030"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(20..1186)
                     /locus_tag="SLE65_001677"
     CDS             complement(20..1186)
                     /locus_tag="SLE65_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEI8448972.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(1198..1551)
                     /locus_tag="SLE65_001678"
     CDS             complement(1198..1551)
                     /locus_tag="SLE65_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEI8448973.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            1679..2704
                     /locus_tag="SLE65_001679"
     CDS             1679..2704
                     /locus_tag="SLE65_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEI8448974.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDRS"
     gene            2720..2881
                     /locus_tag="SLE65_001680"
     CDS             2720..2881
                     /locus_tag="SLE65_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448975.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(3140..3574)
                     /locus_tag="SLE65_001681"
     CDS             complement(3140..3574)
                     /locus_tag="SLE65_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448976.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(3684..5543)
                     /locus_tag="SLE65_001682"
     CDS             complement(3684..5543)
                     /locus_tag="SLE65_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEI8448977.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(5661..6820)
                     /locus_tag="SLE65_001683"
                     /pseudo
     CDS             complement(5661..6820)
                     /locus_tag="SLE65_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
     gene            complement(7127..8551)
                     /gene="araA"
                     /locus_tag="SLE65_001684"
     CDS             complement(7127..8551)
                     /gene="araA"
                     /locus_tag="SLE65_001684"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HEI8448978.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(8567..9265)
                     /locus_tag="SLE65_001685"
     CDS             complement(8567..9265)
                     /locus_tag="SLE65_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEI8448979.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(9222..10883)
                     /locus_tag="SLE65_001686"
     CDS             complement(9222..10883)
                     /locus_tag="SLE65_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HEI8448980.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            11101..12501
                     /locus_tag="SLE65_001687"
     CDS             11101..12501
                     /locus_tag="SLE65_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HEI8448981.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(12753..13832)
                     /locus_tag="SLE65_001688"
     CDS             complement(12753..13832)
                     /locus_tag="SLE65_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8448982.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(13918..14877)
                     /locus_tag="SLE65_001689"
     CDS             complement(13918..14877)
                     /locus_tag="SLE65_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HEI8448983.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(14889..16400)
                     /locus_tag="SLE65_001690"
     CDS             complement(14889..16400)
                     /locus_tag="SLE65_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HEI8448984.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(16422..16985)
                     /locus_tag="SLE65_001691"
     CDS             complement(16422..16985)
                     /locus_tag="SLE65_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEI8448985.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(16991..17854)
                     /locus_tag="SLE65_001692"
     CDS             complement(16991..17854)
                     /locus_tag="SLE65_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEI8448986.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(17868..18764)
                     /locus_tag="SLE65_001693"
     CDS             complement(17868..18764)
                     /locus_tag="SLE65_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8448987.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(18939..20228)
                     /locus_tag="SLE65_001694"
     CDS             complement(18939..20228)
                     /locus_tag="SLE65_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEI8448988.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(20200..21717)
                     /locus_tag="SLE65_001695"
     CDS             complement(20200..21717)
                     /locus_tag="SLE65_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HEI8448989.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            21915..22805
                     /locus_tag="SLE65_001696"
     CDS             21915..22805
                     /locus_tag="SLE65_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HEI8448990.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(22878..23702)
                     /gene="nadE"
                     /locus_tag="SLE65_001697"
     CDS             complement(22878..23702)
                     /gene="nadE"
                     /locus_tag="SLE65_001697"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEI8448991.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(23714..25186)
                     /locus_tag="SLE65_001698"
     CDS             complement(23714..25186)
                     /locus_tag="SLE65_001698"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEI8448992.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(25823..26185)
                     /locus_tag="SLE65_001699"
     CDS             complement(25823..26185)
                     /locus_tag="SLE65_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEI8448993.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            26408..27160
                     /locus_tag="SLE65_001700"
     CDS             26408..27160
                     /locus_tag="SLE65_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEI8448994.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(27300..28223)
                     /locus_tag="SLE65_001701"
     CDS             complement(27300..28223)
                     /locus_tag="SLE65_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8448995.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(28238..28510)
                     /locus_tag="SLE65_001702"
     CDS             complement(28238..28510)
                     /locus_tag="SLE65_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8448996.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT         8477 a         5988 c         4884 g         9333 t
ORIGIN      
        1 tcccatctgt ctctttttgt tattctttct gctttttcaa cggattttct tcataaagag
       61 aagagattgt tgtgtaccat tcaaaaacat gagtaatcac tactttagct gctgcataaa
      121 caggaatccc caagatcaca ccgatgattc cgaacaattt cccagaagtc agcagaacta
      181 ataaaatcgt tactggatgg attgctaact gattccctag tactaatgga gagatcaagc
      241 gtccttctat tgtctgctct actgcaaaaa cgatcagtac tttgatgatc atgaatggac
      301 ctgctacaat ggctaaaaag atagccggaa tcatcgctaa aaatgatcct aagtaaggga
      361 tcaggtttaa aaaacccgca ataatcccca acgtgacagc atactctaaa ccaatgaccg
      421 caaaaccaat cataaacatg attgccacag caaaagccac agttagttgt cctcttatat
      481 aagaagaaac ttgactattc atttcactca gcacattcaa cgtcggtttt tgcatgcgtg
      541 tcggtaaaaa tttgacaaaa taaggtgcta attgtttacc gtctttcaat agataaaata
      601 agataaacgg catcgtcagc agagccacta aaatagtcgc taccgcgccg acaaaacttc
      661 caagactctg aactgtactc ttagatatat cttggatcat atcgcctgcc gaattcatga
      721 acttatcacc tgctgtttcc aactgttcgc gaaattggtt gaacagcggg tcccgcaaaa
      781 tctcggttaa tttattatca atcgtatcta catattgagg gaagttactg atgaagctca
      841 ctgtttgttc ctgaatctta gggatgatca ctacgctccc ccatgcgatt agtgcaacaa
      901 ccaaaacaaa cagcccaatg atactgtaaa gccttggtac ttttcgcttt tcaaagtaat
      961 caactaccgg attcatcaag taatacaaga ttcctgctaa aatgataggc agacctacga
     1021 ttgctaaaaa ttgccagatt ggtgcaaaca aatatgaaac ttttgtaaat aaaaagacga
     1081 tcagcaatat taacaataca acaagtaagg ctgtgactac ttgattattt aaaaaccagc
     1141 gccaaaacca cgataccggt ctgttcttct tattttttcc ttccataatt cctcctgtta
     1201 gttataaaaa atttggcttc ccaaaccaat agcaggcagt ctatgcggat gaagatagat
     1261 tccatttgca atttgtcctt cttctggaca agcatcaaaa atcaatgata cgtgagctac
     1321 tgtctttaaa ttcccattgg ccatcggacc gacataatcg atcgtatata cctgatcatc
     1381 aaaagcaatt gttccgcctg ctttcaaaga aaaaggttcg tcttttgata cttcttgaat
     1441 caccgaatat tttcgtaagg cagctgttgc tgttttatcg aacaaaatca gcatgggttc
     1501 ttccttgttt attgcttctg tcccaatttc tgtaatcttt gcctgaatca ttgcactctc
     1561 tcctttaatt gctttcaaaa acagtataac acattctcat tctttagccg tgtggaataa
     1621 ttatgtgata gaataaaaac gaaaactatt tcattacaat taggaggaat cagctcatat
     1681 gatcgaaaag ataattttag gaacctatac gcgtcgcgaa agtaaaggaa tctatacgat
     1741 cgaccttgat acagaaaaag aagaattagc caacctttca ttagctgttg aagaaaatag
     1801 ccctacctat gtagcaaaaa gtaaagctgg caatctttac acagttacta gtgtggatgg
     1861 attaggtggt gccggtgcgt acgataagga ttttcatttt ttgaatgcgg taacagagtc
     1921 tggcgctcct ttgtgttatg tagcggttga tgaagcacgt caattactat acggggcgaa
     1981 ctatcataaa ggtgaagtaa atgtctacca tatattagga gatggcgaac tgaaagcagc
     2041 agattcaata ttccatcaag aagcgacagg tcctcataaa aaccaagatc atgcgcatgt
     2101 ccactatacg gatctgactc ctgaccaacg attagtcgta tgtgatcttg gtacagatcg
     2161 tgtgtatact tatgatgtgt ccgaaaacgg caaattgaat cttgtaacta ccttcactgc
     2221 agagccagga acaggccctc gccatcttgt ctttcatcca aatggacaat tcgcttattt
     2281 atttggtgaa ttagacagca cagtccgcgt gctttcttat aataaagaaa caggtgcttt
     2341 tgaagaatta cagaaaatat cgaccttgcc agaagaattc gacggtgaaa atggaggggc
     2401 agctatccgc atttcaaatg atggcaagtt cctttatgct tctaaccgag gacataactc
     2461 gattgctgta ttcgcagttt ttgaagatgg ttcccacatt caaaacaagc aaatcatctc
     2521 aacagaaggg gattttcccc gcgatttcgc actagatcca agcaataatt ttgtcgtgtg
     2581 tgccaatcag aacaccgata atctgacatt atatcgccgt catcctgaaa caggattact
     2641 ggaattactg aaaaaagatg tctatgtacc agaatgtgtc tgtgtttatt ttgatcgttc
     2701 gtaagaaaag gagaatgaaa tgaatcagca agacgtatta gacagactac gggaagaact
     2761 aaatattcct ttctttgatg ggaaaatcga agataaagag tatagcgaag aggaatatca
     2821 gaaactcaaa gccgatttac agaactactt tgaacaatat gtacagaatg tagaaaacta
     2881 atcagctttc catactatct gaaaagaaca tcaggacaag acttttccgt ctatcctgat
     2941 gttcttttct acaaataaaa aaccgccgag atggttagac tcgacggaaa aggagtattt
     3001 actcgatttt gagtaagtac aaggttgttg ttggttatag gtatgtcatt atcataaagg
     3061 attttgatca ctctatcata aaggtaatat tacatttata ttagataact ctagttttta
     3121 ttgttatcaa agatttcttt tattttttca acaacaaatt agtcattttt tggatggcag
     3181 ctgtcaattg gtctgtcgct tggtcttgtt ttgcttcaga tgtattgaat agatcttcat
     3241 ctacccctga ttcaagatcg atactttgga tcatttcttc acagcctgct acatatgaaa
     3301 gataagcttt ttcaaaattt ttatgaatgc ccattgcttt tgctggtgga cgcaaagtac
     3361 tgactttcat aagcattgcc cgatattttt ttgttccttc ttcaaataac aggatgatct
     3421 cttcaagagt cgatttgtcc agttcacttg tttttccttc atcaattgcg tttctgatca
     3481 cttcatattt cggatgcatt ccttctccga ttgcttctgt ttccttgacg atttgatcga
     3541 tggactgcac ataatagcca atattcggta acatgttcgt tttcctactt tctccattgt
     3601 tgttattatt tattctactt gtttttatcc tcaaatgaca agtacttgaa aaaatttaat
     3661 ggtttctata cagctcgcca ttcttattcg tgctcaaaga aaccatctgc taaactatat
     3721 tgtttccctg cgacaatgtc atattggatc aattgatatt cgtcgtaaat ctcttgttgc
     3781 gagcgattga attgcgcttc tttataccac tgtccgtttt gatagtacag ttctcgttca
     3841 aacgccggaa gttcctgttc taatgataaa agcagctgat aaaagccatt tgttgtctga
     3901 ttcgtctgtt ccattagatt cgctgcaaaa taaaacggac tggtgattgc atcgtgagtc
     3961 gtttgctttt ctaattctcc tttactgtcg aacataagaa attgtgtttc atgcaatgtt
     4021 tgtttgtcat tttttgcttg gatcgtatct gaatagatcc ctggaagatg atccccccaa
     4081 aaaacaacta aagtccttct agaaagattc ttcaattctt ccgtgaactg cttcagtgcc
     4141 gtgctgctat aggaaatatc ttgcagataa ttctctaagt caagtgtccc acttccatct
     4201 gaagtttttg caggatagtc tagattatca tactttccat cgtagggcat atgtgtctgc
     4261 atcgtgacta aatgaatgaa ctgaggtgtt ttttcttcct tgagaagtgt cattacttct
     4321 ttgtaagctg actcatcaga aatatatgga ttattctcta tcgtatccgt ataggtcatc
     4381 gtacgctcgc tgatgaactg gtcaaatcct aatgtctgat aaacatcctc tcttttatac
     4441 atcgaagtat tgtatggatg gatcgctgtc gtctggtatg attgtgcgtt taacgctgaa
     4501 acgatagaag gaagctgatc catttttggt acaagcatcg tgtaaggggt ggtgagttgc
     4561 gcattaaata acgccataga aaaaccagtc aatgcttcaa attcgatatt tgctgttcca
     4621 ccgccatagt tttgagaaag catattgcca ctatatgttt gatcagctac ttcataataa
     4681 tctgccaatg gctcaccaga tacttctacg ccgtttaatc gactaggatc tgagaaactt
     4741 tcactcatca cgaacacgat gttcggcgac tcttcctcta cagttttatt tttttcatcg
     4801 gctagcttct ggtatttttc agtgatttct ttgatctttt ctttcgaata tccttcaggt
     4861 tcatccattg gttctacctt cagattgtac aaaaacccac cgataaaacc agtgttatag
     4921 tagttcattt tctggctgta aggtatccat agtgccgttt tattatatgc ttttcgcaac
     4981 aaattatcgg gattgttgaa attactgata taccctagca gtccaattgc cacaagcagt
     5041 gtcgttaatc ggatcaattg gaatcgcctt ccttttttca ggcttcgaaa catgtaccag
     5101 caaaacaatc ctatcacggt tcctgcggca gctaagatca ctgtaaacag catagtgccg
     5161 gtcatatctt tcagcaatcc gatttcagtg atcatcttca aatcgtctgg ataaatcggt
     5221 tcttgccgat aactcatttt catataattt gcaaaaccta atacaccgat ggctacgaca
     5281 tacgtaaggg aacctaaagg gacagatcct gctagtgcaa tcagaaaaat aagaataatc
     5341 agcaagacga gacaggctaa gaagaatttt tccgtatgcc aagaaaaagc aaatttcaac
     5401 gcaaggtcta cggatagatc attttgacac cactgcaaaa ataaattact aaaaacaaca
     5461 agaaaaaaga tactgatgat tgctgctgtt ccttttaaaa tctttttctg tttggtcgaa
     5521 agtctgctta tatatctttt caaatgcttg ctccttcatt tctatcaata aaagaatgtt
     5581 gcttctctta ttttagttgt acgaaattcg aaagtaaaga acggaaagaa gaattaatga
     5641 aatccaaata ttctctttct ttatggcctt tctggtttct ttaataagcg gacctttcgt
     5701 actccagaaa ttttttctag ctgttgtttc acttgattga gctgttcaaa atcagtactg
     5761 tctatgtcaa tcaatatgta gacatgctca ttcttatggt tacgcgatat atctgcgatc
     5821 gctagctcgt tctcattcag cagagaaaat atctctgcta atatattggt tttcttttga
     5881 taaaatatag tgaatcgaaa cggcgcttgg aaaaacattc gtgcggatgg ataattgacc
     5941 gcttctctaa ccgtaccgaa caaaagataa tcttttaagg cttcaactgc caaacgtccg
     6001 ctgtctgcca aagcttcctg agtcgatccc ctagatgagg caacataagt atacggtcat
     6061 tttctaagaa ctcttcttct ggaaaatcag tcaagtattt agccagatgt tgtttttcca
     6121 atgcttgcat aacagcatat ttatcaacaa tttcacttct tcctacattg ataagtacag
     6181 catctttttt cattttttct atattcgcct gatcgatcaa tccttttgta tcttctgtca
     6241 acggcagcat gactacgatg taatccgagg tagaaagaac tgtttctaaa tctgcttgcc
     6301 gaacataatc caactgggca tcgcggatag aataacccaa gacatccatc cctaagctat
     6361 agcaacttag cgctactttt gtgcctatcg ctccaagacc aagaagaccg atggttttgc
     6421 cttgcaattc tcgtcccaca taagcacttc ttttgttttc tgcctgttct aaaatattag
     6481 gacctgttag tgtttgtacc atacgacttg cttcgattat cggacgggaa gataagagca
     6541 aacagcacaa aacaagctct tttactgcat tagcatttac acctggtgta ttcatgacga
     6601 tcgtcccgtt ttcagaagct ttttcaacgt tgatcgtgtt caccccaaca ccagctcttg
     6661 aaattgctag caaatctggt gtaagccatt catctttcac tttcgtacta cgaataacta
     6721 ttccttcggc tggcaaatca tctattattt tgaaatattc cccttgtaac ttttctatct
     6781 cttgttctgg aatagcatca atcaaatgaa cgtgatacat aaaaccccct ccttactaac
     6841 aagtatctcg aaatttctgc aattagacaa ctgtttacca tttgacttcc tagaagcaaa
     6901 aagagcagtt agagcagagt aggctgagtg ataaaaataa ggctatgaca agttactgcc
     6961 ataagcctta ttttcgagag caaaatattg agggtgagat atcttgataa atggtgttcc
     7021 gttagctgac attgataata agactaaatt tcaaaaaagt tgaaaagcaa atttcgtcaa
     7081 tctcttctta tttcttaaaa ctaagtggct ttttcacaac ctctttttat ctaataacca
     7141 ctgtttccaa ctcaactaat tttgcccacg tttcaatttg atctgttgtt agatttagcg
     7201 agacaacggt atgatgaccg ccacctgcct gaatccatga atggacacct tcatggaaat
     7261 tcggtttagt tttccataac acacgtgcaa caggtaaatt aggtgcttca gtcgttggtt
     7321 caaaggcttc tacttcattg atcagcagtt tataatgcgt accgaaatct gccatcgata
     7381 cgactacccc ttctcctgct ttcccatcaa atacaagacg cgccggatct tctctatctc
     7441 ccattgataa aggagaaaca acgattcttg gtttcgtcgc agcaagcgtc ggatctactt
     7501 ccatcatatg ggattccaag attgcttctt ggccactagc tagctcgtaa gtataatctt
     7561 ccatgaatcc tgtatctttc cctcgagcca tgattttcag caaccgatca atcgctgcag
     7621 ttttccagtc gccttcccca gcaaaaccgt atccttctgc catcaaacgt tgtacagcta
     7681 gtccaggtag ttgtttcatt ccatacaggt cttcaaaatt agtcgtaaaa gcgttatagc
     7741 ctccttcttc taagaaacgg cgaataccga tttcctgctg agcttgtact tttacatgtt
     7801 cctcccatgt cttttcttca taatcaccat agtcgaaggt atacaattcc ttgtactctt
     7861 caaataattg atcgacttct tcgtctgata cgcgatcgat tacttgtaca agatctccga
     7921 taccaaaata atcaacagtc caaccaaatt gaatctgtgc ttccactttg tctccttctg
     7981 tgacacccac gtttctcatg ttgtcaccaa aacgagccac ttttattcca aaactttcat
     8041 tataggctac tgcaacatcc atccaatcag caatctcttt ttggatctca ggtcgtttcc
     8101 agtagccaac gacgatttta ttttgtttat ttaatcgagc attgatgaac ccatattcgc
     8161 ggtcaccatg agcggattga tttaaattca tgaaatccat atcgatcgtt ttccaaggaa
     8221 tgctttcgtt atattgcgta gctaaatgaa gcaatggttt ttgtagaagc tttgtcccgc
     8281 ggatccacat ttttgctggt gagaaagtat gcatccaagt gatcacacct gctacttctt
     8341 ctcgataatt gacctctttc atgatttttg tgatcgtatc agcagtaact gctaattctt
     8401 gaaggcggat tggataaggc aattggccat tttcattcag ttcatcgacc atttcttgtg
     8461 catgtttctt tacttctcgc agtgcttctt ccccatataa atgctgtgat cctacaacaa
     8521 accaaaattc tttttctcca atattcaaca taattagcca ctccttttat ttgttttgtc
     8581 cgtaatacgc attttttccg tgttttcgta aataatgttt atctaaaatc cgttgaggca
     8641 gctcttctga aaatgaattg agctgtctgg taaataaatt catcttgcat acttcatcta
     8701 gtacgactgc gttcattacc gcactttgcg catctttccc ccaagtaaat ggaccgtgtc
     8761 cgtgtaaaag tacccctgga attgctaagg gatcaatttt gcgttctttg aatgtttcta
     8821 tgataacttt tcctgtttca tattcgtacc cgctgtcgat ttcctgttgt gtcaaaaatc
     8881 gagcacaagg taccgatcca taaaaagtat ctgcatgcgt cgtccccatc gcaggaacat
     8941 ccaatcctgc ttgtgcccag atcgtcgccc atgtcgagtg agtatggacg attcctccga
     9001 tttgaggaaa tgaacgatat aaaacagcat gagtaggcgt atccgaagag ggattgagtt
     9061 taccttcaat gatatgattg tccaagtcca caacgaccat gtcgtctgct gtcatctctt
     9121 cataactgac tccgctaggt ttgataacga aatatcgtgt ttcaggatca aaagcgctca
     9181 catttcccca tgtatatttg acgagtccgt gtttaggcaa gtcaagattt gcttggtata
     9241 cttcttcttt cagttgttcc agcattttct atcactcctt tttcttgcaa ttgatgaatc
     9301 gctgtttttt caatgtcgat cccctcacgg taacgtctca taaatatctg atagcctgct
     9361 atttcttctg ctgaaggtgt gatggtgatt ccttggtctt gtccaaacac gtcttctgcc
     9421 aagaagtttt ctaaagactt cccatgtcga tccatcatat aggctgctaa taacgcgatt
     9481 ccccacgctc caccttctcc ggctgtgtcc atcactgtaa ctggtgcctc catagcagat
     9541 gctagaatcc gctgtccaac ttctggtgtt ttaaaaatcc ccccatgccc cactaaacga
     9601 tcaatttgga cattctcaga tttcaatata tccattccga ttctcattgc accaaaagca
     9661 ctggctaaat ggatccgcat gaaattcgct aaatcaaaac ggctacctgg tgtacgtaca
     9721 aataatggcc ttccttcatt tactcctgta atgttttcac cggaaaaata accataagaa
     9781 agtaatcccc cgcaatccgt atcgccttct agcgctttgt tgaataatac cgtgaataat
     9841 ttatctctgc ttatctccat acccaaagaa ttggtaaatt cttcaaaaat actgacccaa
     9901 gcattgatat ccgaagagca gttattcgta tgaaccatgc ctactagttc tcctgaaggt
     9961 gtagtgacca tgtcgatttc cggatggaca ttttctagtt ctttttctaa tacgatcata
    10021 gcgaaggcgg aagtaccagc cgaaatgttc cctgtccctt tggctacact gttcgtagcg
    10081 accataccgg ttcctgcatc cccttctggc ggacaaaccg ggattcctgg tctcaaattt
    10141 cccgtagggt cgatcagata agcccctgat tcgcttaact tgccagcttc ttctcctgct
    10201 actagaactt taggcaaaat gtgatccaag tcaatcgcta cgtgcgcttt ttcgattaac
    10261 tgaccaaaaa tatttttcat ttcttgatgg taggttttcg ttgaaggatc gataggaaac
    10321 atgcctgatg catctcctac gcctagtact ttctcaccag taagctgcca atggacataa
    10381 cctgcaagcg ttgtcaaaaa attaatttct ttcacatgtt cttctttatt caaaatagat
    10441 tgatacaaat gagcgatact ccatctctgc ggaatattgt attgaaattt ttccgttaat
    10501 attcgttctg cttcttcagt gattgtattt cgccaagtac gaaatggtac tagtaactgt
    10561 tccttgctat caaatgctag ataaccgtgc atcattgcac tgaacccaat cgacccgatt
    10621 gtcgtaagat tctcgccata gatttcgaat acttctgctg ccatttttcg gtaactgacg
    10681 cgcagtcctt tccaaatatc ttctaatgaa taggtccaga taccattttc tagtttgttt
    10741 tcccactcat aactaccagc ggcaatagga gtaaaagatg aatcaatcaa tacagctttg
    10801 atcctagttg atccaaactc aatccctaaa gatgtacgac catctatgac atctaacata
    10861 ctttgcgcat ttacttcctt cataatgatt taactccctc cttctcgtca aacctgatca
    10921 aaccgtcttt ttagtagcgc ttacaatgat tattgtatac ttttgtacgt acatgtcaag
    10981 cagttattta caagaataca ataaaaaaca cttgttttgt acgtacataa gttataaaat
    11041 gaaattgctt acaaaatctg atcaaccgcc ttctcgaaat tctagaagga gagaatactt
    11101 atgaaaaaag aaaaaaaagt ttcctcatcg tttatttatt tttttggcgc atttggcggc
    11161 attctatttg gatatgatat tggtgttatg accggcgcct tacctttttt acagcatgat
    11221 tggggtttgg caggtaaagc ttctttgata ggatggatca cgtcttcggt catgttaggt
    11281 gcgatccttg gcggctcttt atctggtctt ctttctgata agcttggacg acgaaaaatg
    11341 attcttcttt ctgcacttat ttttatggct ggttctgtcc tttctgcatc tgcccctcac
    11401 aatggttctt attttctgat tgcagcaagg attcttctag gtttagctgt tggcgctgca
    11461 tctgccctag ttcctgctta tatgtctgaa atggctcctg ctagactaag gggaagattg
    11521 tcagggatca atcaagtgat gattgcttct ggcatgctcc tttcctatgt tgcagattat
    11581 ttgctaaaag ggttgcctga aacgatggct tggcgcgtga tgttagggct cgctgctgtc
    11641 cccgcgctga ttttattttt cggtgtttta gctctaccag agtcaccgcg ttttcttatg
    11701 caatctggcc gcttggaaga ggcaaaaaga gtattgaact atattcggac accaaaagaa
    11761 gctgaacagg aattcgaaca aatccagctg aatgtcaaac aagaaaagac aaccggaact
    11821 tcttggcata ctttgttttt agaaaaatat cgttccttag tcattgccgg tattggtgta
    11881 gcagtattcc agcaatttca aggagctaat gctatttttt actatattcc gctgatcgta
    11941 gaaaaagcga ctgggcatgc agcgagcgat gcattgatgt ggccgatcat ccaaggaatc
    12001 attttagttg ctggttcttt gctctttttg gttattgcag acaagttcaa tcggcgaact
    12061 ttattgaaaa taggcggtag cgtgatggga ctttctttca tcctaccagc tgttttagga
    12121 actgtactgg atgctcatac aaattcgttg ttgattctct tgtttttatg tatttatgtc
    12181 gcattttatt cttgcacatg ggctccactg acatgggtaa tcgtaggcga aatattccca
    12241 ctagctgtcc gcgggcgagc atctggccta gcctcttctt ttaattggat tggttctttc
    12301 ctagttggct tgctttttcc tgtgatgact gcttctatgt ctcaagaaat cgttttcggc
    12361 atttttggga tcatctgctt tttaggggtt ttatttattc aagagatcgt accagaaact
    12421 cgtgggaaat ctttagagga aatcgaacaa agtgcatcta aaaaaactta tcctaaacgt
    12481 atttctatcc atcattctta aagaggttgt gacagaagtg gtcagcttca agaaataaga
    12541 aggaaccgct tagtttccag tcacaaggaa caatttcaaa aaacagcttc tcatgtttga
    12601 tgaatattgt gacttgtgac cagttggtag gagaacaccg tttagtggag aggtggtgaa
    12661 agaaacgttc agccttgagc gatgacaaaa gctctcacaa acattgcgac gagtaaccgt
    12721 aggagcaata agaggcggta aaaacccgtc tcttattttt cgttttcttt cactgtttcc
    12781 cgttcaacta gtacaggttc atagagaata tttggctgtg cctgtccttt ttcaatcgtt
    12841 gtgacgatcc accgtgcggc atcttgtccc aacttttctt ttggatgcgt caatgttgtc
    12901 aattttttat tccctaaatg gcttaaagaa gaatcgtctg ttcctacgat cgataggtca
    12961 tctggaatat gatagccatt ttctgtcaac ttatctagca ttaaactagc tatttgatcg
    13021 ttatagcaaa tgatgccatc taaagcttgt tcttctttca accgttgtac tgttttttca
    13081 gcgattgttt ctcgtgtttc cgtggtgaaa gtaatgatat cttccgtcaa aaaacgcaca
    13141 ttatactgtt cacacgcgct gataaaacct ttcatcctgt attttccttg aagatcgtcg
    13201 atttttgtga tgaacaacag acgctgatgt ccttttttta tcaaatattc tgctgccata
    13261 aaaccgactt tcacatcatc taaacaaata taagaggcat ttaactcttc ataagcagca
    13321 ttgatcatca ccatcggaat gccttgttct ctcaaagcaa cataaagtgc taagtttggg
    13381 ttatactgat tacttttcgt aggctcaacg atcaaaccat ctaccccata agcaatcatt
    13441 ttcttcaaac actctttctc caattcgtga tcgttattcg tactggctaa aagcaatgaa
    13501 tacccagatt ctcgtaattc attttcgatt cctcggataa tcgacggaaa aatataatca
    13561 gagagatatg tggtgatgac accgatcgtt tttgttctgt tcaatggtgt tttttctttc
    13621 ttatagctgt catctacata tgtgcccgac cctttttctt tacgcagata gccctcattt
    13681 accaacacag cgattgcttg ccgaatcgta tgtctgctga cgtcatatat ttcttgcagc
    13741 ttgaattctg agggaatggt tgtatttact tcgtattcct cacgaaggat cttttgtttt
    13801 atctcttctg caatatcttg atattttgcc atttgccttg ccccttttta tttgtacgta
    13861 catatatcat aacgagtctg caaggtttat tcaagcaaaa atcaaggttt cttgtgctca
    13921 taaggcatac ggaacaggtt caccaaattc tggaaatcct tgctcattcc acgtaaagca
    13981 ttgcgcgttc gcgtgccgat taggattgtc taacggatcc cctttttggt tcttctctgg
    14041 tcgagcatga tagatcaaaa tatcaaagca cccgtcttct gaaaccgtaa acgagttgtg
    14101 accaggacca aattgcttat ttttttcaga agaaacgaat actggctccg ataatttatg
    14161 ccatgattct tttaataaaa gattcttgtg ctcatcagcc cacagcaggc ccatggcata
    14221 gttttcatct gttgcactac cagaatacgt aatgaatatt ttcccattgc gagtaaggac
    14281 tgctggacct tcatttactg aaaaaccccg tttttcccat tcatactcag gtatagaaag
    14341 gaggatctgc ttccccttta acgtccaagg attatccatt tcggatagat aaagattaga
    14401 attcccagta atttcaggat cttgttgggc ccacacataa tatagctttc cttgagaaga
    14461 gaaagttgtt ccgtctaaac tgaaagtttc ccttttcgtt tttatttgtc ccttttctat
    14521 ccaatctgta ttcattggat ctatatgctg attttcaagt acgaacatgc ggtgatgatg
    14581 agattcatca cgtatagttt tatgattgct tgcagcaaag taaatatacc attttccatt
    14641 gatataatgg acttcaggtg cccagatcaa ttcactcatc ggtccttctt catgagcctg
    14701 ccatacaatc aggcttgcag catgttctaa ttcattcagt gactttgccc ttcttaattc
    14761 aatcacttgg tagcctggaa ccgatcctgt aaaataataa taaccatctg tatgtttata
    14821 tacccaagga tctgcccgtt gccgaacgat aggattatta taaagtgtct tcatcataac
    14881 aaatttcctc acattttctt tattctaatt acattccaag agtatttttc tatccctaca
    14941 tttaattcgt catgtttttc tattgaaaaa tagtttattt caggttttat tttttctggt
    15001 tcttcacgtg tatttttgtc caacagatcg ctactggtta atgtgtagtg ctctccttga
    15061 tctagcaaat tgaaatcatg ttcaatcgtt atcttttgtt gttcatttgt gcgattgatc
    15121 aagaaaatag tcagctgatt gccgttatct acgatcacac tgtccacata aggaacattt
    15181 tttatctttt cacaatcata aacagggcaa atgatttgtt gtttcaatac ttgaccttta
    15241 gcatatttcg ataagtgttg catcacataa taagttggat tcctccatgc ttgtccttta
    15301 gcatctgtca gtattaaagg tattgtgttt actaacaatg attgacaact aatctttacg
    15361 cgatctgcgt gtcgtaaaat agccagccct aatgaaccaa ataataatgt atcttccata
    15421 gtaaagtaac accaatcgat gggactaccg acttcaaaat ccctatgtct tttttccggt
    15481 tgggcatgta cattccattc atcaaacgct agatacattg ttttctcact tctcaaatat
    15541 ccttttacat aatcacaagt agcaacgatt tcttcaattt gacgatcgaa tcgataagct
    15601 tttgcaaggt atgtcgctgt atcatcacgc tcatttttag gaggtttagt caagtcttct
    15661 tcatcatact tatcaatata gttatgcaaa gctaaataat ctacattctc ataagcttct
    15721 tctaatgcga tacgatccca ttcagggtac gatggtaaac gtggcgtaga gcttccaact
    15781 aagattgttt caattgaatc atccactaac ttcatgactt ttgaggcttc atttgctaac
    15841 ctaccatatt cataagcact cttagccccc acttgccatg gaccgtctag ctcattccct
    15901 aaacaccata atttaacgcc aaaaggcttt ttttgcccat tttttattct taaatcactc
    15961 cagaaggttc cttttggaaa attacaatat tctactaaat tttttgcttc atcaattcct
    16021 tttgttccta aattcaccgt gaatatcggt ttcgcttgta catgactgat ccatttaaaa
    16081 aattcgtgga gtccaaaaga atttggttct atacctcgcc atgctaaatc aatttttttt
    16141 ggtcgttgtt ctttcctacc tacagtatcc acccaatcat aaccagatgt aaagtttcct
    16201 ccaggatagc gaatgacacc taattctaat tcctttacat aagagaggac atcttgtcta
    16261 aacccgtcac catcagctgt ttcatggccc ggttcataaa tccctgtata gacgacactt
    16321 cccatatgct caacaaatga gccaaacagc cgagaactga tctctcctac cgtaaaatcc
    16381 tctctgattt ttactttcac ttcttcgtcc aacagctttc cctacctttc atttcctata
    16441 gtcaagataa tagatacaag tttccatacg ccaccagcaa agataaaaat aaaaggaggg
    16501 aaaagaaata tgagcagtac aaatcctaat aacaatacgc aacaaagaat atttctcaaa
    16561 aaatcaaaaa atactttcca tgcactttgt tcaaaaattt gtaaaaatgt gatatctttg
    16621 ttttcagaaa tcacatatat ccaggataaa agaaacatgg aataaataag taaaactaca
    16681 tatccactaa ttgaaagtac gattgtctgt tcttctaata attgattaac aagaaaataa
    16741 ataatgatcg ttaacagact aaggaacaag ttcttaccaa aatgttgctt tattccttga
    16801 aagaaaaaat aaatgatatt tcctgatccc tcacctttcc attgcgccat tacataaaaa
    16861 acagcacatg tagcaggcac gatagtaata acaggcaaac acacgattac ccagagaata
    16921 cctaataaga tgtaatcaga aaccacaatc aactgtccat aaagtttagt ctcaactatt
    16981 ttcatcttcc tcactctttc attccagaca tagctgttcc ttgaacaaaa tatttctgtg
    17041 caaaaatata aaccactagt aatggcagca ttgaaataac cgttccagcc attacaggtc
    17101 cataaaaaga aatgttctgc cctgtaaata aagctaaccc tgctggtaaa gttctcattt
    17161 ttgaactact tgtcaatatc aatggataaa gcaagtcatt ccaactattc atcagcgtga
    17221 aaatccctaa tgataaaaga gtaggtttgc tcaatggcaa catgattttc aaaaaaatat
    17281 taaactcact taatccatca atgcgtgctg cctcttccaa agaatctggt aaagtaataa
    17341 aaaaggaacg catcatgaag ataccaaatg cagttgtcat acgaggaatg atcaaacctg
    17401 cataagtatc aagcatgcca agcaaattga cttcaataaa tagaggaatc atgaagactt
    17461 ggaatgggat catcattgtc agcaaaacga aatagaacaa aactgatttt cctttgaaac
    17521 gcatacgagc aaatgcatac cccgcaagag aatcaaagaa tacagaagtg atcactgtcc
    17581 ctccagcaaa aatcactgta tttttgatgt aatctaataa agggatcgtt gtccaaacct
    17641 taatatagtt atctagggta tagctatctg caaatattct aggcggaaat gagataatgt
    17701 ctttttcgtg tttaaaagaa gaaataatca gccacaaaaa aggaaacgca ataaccaaca
    17761 atataactag catactaatc gttcgaatga tttttttacc actaactgct tttcgactat
    17821 tcacagtaac tgtaatcgag ctttctggtg ccatacaggt ttccctccta tttcatttgt
    17881 ttttctttcc gtgacatgta cacattagtg gagatagcta tagttgcaac aatgataaac
    17941 aaaaccgaag acagtgctga tgcatagccc aattcataag gtgctgtaaa tcctcgactg
    18001 taaatatatt gaacagctgt ttctgtctta aattgtgggc caccagcggt tgcaacatat
    18061 acttggtcaa acacttgcat cgaaccaatc agattcgtta aaatacaaaa acctaaggag
    18121 ggaacgatct gaggtagcgt aatgttaaaa aactgctgtc gatttgttgc accatccatt
    18181 tgagcagatt catacaaaga gggagagatt ccctgaatag cagtcaagag aatcgtcata
    18241 gtaacaccaa aattcttcca aacagtcatg atggctaccg tcggcatagc aagggttgga
    18301 tcgcgaaaaa attgagggat cggcaagccg acttgtgaaa acaagtaagg aatcgcccct
    18361 acattcggat caagcaacat agaaaaaata atcgcaattg acgtcaatga acaaataact
    18421 ggaatgtaaa atgtcgaacg acaaaaacga ttgaatctgg tatttttaga taatgctact
    18481 gctgctaata aaccaacgat aatttgtgtt ggcgtttcga gtacggtgaa atataaagaa
    18541 tgaatcaacg aattaactgc tcgttcatca ctaaatatac gtgtgaaatt ttcaaaactt
    18601 acaaaatttc ttgatgtaaa gaaaatattc aaatctgtaa aactaatagc aaatgttcct
    18661 aaaagcggta tgacagtaaa taataataaa actaaaaaag atggagttaa aaacaaatac
    18721 gcagcacgat caggacgatt ccaatatttg gtgaatccgt tcatatagtc cacctcatct
    18781 ttcattttga taaaatatac aatcttggtt taaacgaatc tgaataagat atccgaacaa
    18841 tcgctgtgat ttttgcaata acacctatct gcaaatacta ggtcgatcat tcagatatct
    18901 gtatcttgcc aacagtctat cctgtataaa gttctgtact atttttgcag taattgattg
    18961 atggcatcat ctgcatcgtt catgagtgtc tcaggatctt ctcctgctaa taatttttca
    19021 atcagtggat tgatgatatc gttattgatc gcagagattt gggtaaaacc tggtaaatat
    19081 ggctctgcat agtccatttg tttcgataat tcagatacaa taggatcatt ttttacttct
    19141 tcatcttttg ctactgaatc caagtaggca ggaaaaccat tttcgatact ccatttttta
    19201 ccaatttcag ttgtattcca atatttcaaa aactcataga cagcttcttt tttattatta
    19261 tctgtacttg ccggaatggc atatcctacg ccatctaaaa tagctgtttt tttgtctgaa
    19321 tcactccctt gtggtaaggt agtcacatta taatcaatct cgtttgcttt caatccgtta
    19381 tttaaccatg gcccattgat ttcaatggct agttgaccag cattcattaa attgtccatt
    19441 tcggcgccag aaatcgattc tggaccagtc ttgtctacat ggatcatttt ttggatcgct
    19501 tttaacgttt taaggttctc aggagacgca aattcagact tagtataatc atcgttcact
    19561 aatttaccgc catttgctaa catccagtta tataacggtg cagttccatc cttattgaag
    19621 acaaaacctg atacattttt actactatca gttaattttg gtgccatttc tgtcaattct
    19681 tcccaagtag taggtggttg ttcagtatct aatccagctt gtttaaacaa atcattattc
    19741 caatacatat acatgccttg tacctgcatg gggacaaaat actgtttacc ttctacttca
    19801 cctaattcaa tagccgtttc tttaaaatca gatttatcta ctccatcata ttcccagaaa
    19861 tcgtctaatg gttgtaccgc tccgttttct acatactgtg caaaatctgg ataatttaat
    19921 gcaataaagt caggtgcttt tttagaagaa atcgctgtag gaagtttttc attcaaattg
    19981 gcccaagtca tgatatccat ttcaattttg atgtttttat catttgtttt attaaattca
    20041 ttaacgattt cttgcaatat ttcaccatca gatgcagtaa acccattcca aaaagtcaaa
    20101 gtcacttctt tatcagaatc agattctgct gaacttccgc caccgcaagc tcctaaaata
    20161 cctgttgcag ctaccaacaa agagccaatt aaccattttt tacctttcat tttttgttcc
    20221 tccttcatct gataaacgac atctgaccac attccaagat agcggtttca ataaacaatt
    20281 gattttccca tcttcagctt ttacatttgt tgaatgactt ggttttactt gttcactttt
    20341 aggaagatta gttgcttttg tatcaaatcc actcatttca gaaaaatcaa tcactccctc
    20401 taatgataat tcagacaagt gaacagttag attcatttct tcttctccac ggttaactgc
    20461 aaatatgaca agttctttgt catttattac ggctatactt tctaaatacg gcacttcttc
    20521 aaaatcttcc gtcgcatagt ttgctgaacg aatttgtggg cttaacacct ctccttgtcc
    20581 atacacagca gcttgcataa atggataata gatcgtctgt ctccaagctt ctccgtttgt
    20641 ttctgtcctg attggtgcaa taacatttac caattgagca agacaagcaa tctttactct
    20701 atctgcatgt ttcaataaag tgattaatag acagcctaat agtaatgcat cttcaaaatt
    20761 atagttatct tctagtaaag gaggagcaat ctgccaaggc gctgcttgct catcttgttc
    20821 cgctgaatga taccaaatat tccattcatc aaaggacagg ttgatctgct tcttactatg
    20881 tttcttcgcc ttgactgtat cgcacatcgc tgtcacttca gaaatgaacc gatccatgtc
    20941 taaggaacgt gcaagataat gagaaagatc atttttttgg ttgccataat attgatgcag
    21001 agacaaataa tctatttgat cgtacgcttg atcaagaact gttaactccc aatcaccaaa
    21061 tgtaggcatt tgccgattcg aacttccgca taaaaccacc tcaattgaat catctacgag
    21121 tttcatcgcc ttagccgttt cctctgctaa ccgtccatat tcttccgctg ttttatgtcc
    21181 aatctgccaa ggaccgtcca tttcattccc taaacaccat gtcttaattc caaaagggct
    21241 ctcttgacca ttcgaacgcc ttaaatcact ccaataagtt cctttaggaa aattacaata
    21301 ttcgactaaa ttacgagctg catctactcc acgagtaccc agattgacag ccatattgat
    21361 ttcggccccc acatgctgac accagttata aaattcatga atcccaactt cattcgtttc
    21421 aattgtccgc caagctaaat ccaaccttct aggtctattt gctatgggcc caatactgtc
    21481 ttcccaacga aatcctgaca caaaatttcc accaggatat ctaatcatgg gaatgttcaa
    21541 ttcttttacc aagtgaatga cgtcttggcg aaatccactt ttattagctg atggatgatc
    21601 tggctgataa atcccttcat atactgctcg tcccatatgt tcaataaatg aactgtacaa
    21661 ccgcggatca actttgccta cacgcttgac actactaatc aacattgtgg cttccataac
    21721 tgacctcctt taatttatac atgaataata cacctcgttg aaagcgttgt caataatata
    21781 aatgttaaac ttacttattt tttatcgatt ttaattaacc aaaatattaa taatgattaa
    21841 aacaaataat ttaatataac ttttattaac aaatatgtta atatataaga aaaacctttt
    21901 aagaggtgat atatatgcaa ctacaaataa acgaagaatc cttaccggta tatgaagcat
    21961 tagctagtaa aacaaggatc aagatcatcc agctactttc caaaaaaaag atgaatgtca
    22021 aagatttggc aaaagaactt ggagtgagca gtgctatcac gacgatgcac gtgaaaaagc
    22081 tagaggaagc aaacatcatc aaaacagaaa aagtaggaca acaaaaaatt tcgagccttc
    22141 gtgtcgataa aatcgatatc agttttccag aaaaaatatt caatgctttt gatacgaaag
    22201 aaacatcgat acctattggt cactatacaa attatgcaat tgaaccaaca tgcggtttag
    22261 ctacgatcca tgattttatc gggaaagtgg atgaaccacg ctattttatg gatcctcgaa
    22321 ggatggatgc ccgcattctc tggtttacca gcggatttgt cgagtatcag gcacctaatt
    22381 ttttaaatac agaggataca ttggagatgt tggaagtttc tgtggaaatt tcttctgaat
    22441 ttcctttttc aaatgacaat tggccttcag atatcacttt cagcctaaat ggtgtggagc
    22501 taggaacatg gacgagccct ggagattttg ctgatatccg cggtaaatat acgcctgatt
    22561 ggtatccaga taatcttaat caatacggct tgctgaagac gatccgaatt accaaacact
    22621 tgacgaatat gaatggagaa cccttgtcaa acatcacgat caacgacatc cctaaagagc
    22681 aagacacttg gcatttgcga atcgaagtga aagacgatgc caaacatgtg gggggctgta
    22741 ctttatttgg taaaggattc ggtaattacg atcaggatat caaattaaaa gtttactaca
    22801 gctgatattt ttcttttcta ttttataaaa caaaaacagc caatccctat gaagggacgg
    22861 ctgtttttgc tttattgtta tttccagaaa tcatccaaaa cggaaattgg caaatgtcgt
    22921 ttatgttgtg tcttgttcca ccatgcttcg attttttctt gtgcttgagc gggaacttct
    22981 tttccttcta gataatcatc aatttcatta tatgtgacac ctagtgcgac ttcatctgca
    23041 atcattggtt tcccatcttc aagatctgca gtcggaattt ttgtgtataa tttttccggt
    23101 gcattcaatg cttgaagcaa ttgtttccct tgtcgtttgt ccaaacggaa taatggcaaa
    23161 atgtcggctc caccatcacc aaatttcgtg aagaatccag taatgttttc tgcagcatga
    23221 tctgtcccta atacggctcc tgctctttct ccagctacgg catattgcgt aatcatacgt
    23281 tgacgtgctt tgatatttcc tttgttaaaa tcgctgattc ccacacctgc ttcgcttaat
    23341 acttgtactt gtgcatcaac agctggtttg atatttactc gcagactaac atcgggctgg
    23401 ataaagtcaa gagcagcttt tgcatcttct tcatctgctt gttcaccata aggaagacga
    23461 acagcgataa attgatagtt ttcatctttt gtttcttcac gcatttcttc catcgttagt
    23521 tgcgccaaac ggcctgctaa agtagaatct tggccgccgc tgatacctag tacaaaagtt
    23581 ttaagaaacg gatatttttt caaatatgct ttcataaagt caatactttt acgtatttct
    23641 tcttttggat caattgttgg tttgacacct aattcattga taatttctgt ctgcaggctc
    23701 atttattctc ctcctatgct tctgtatgaa gttctgctac gctttttttc attcgttcca
    23761 tgatagccat tttatggttc cagcattcag tagacagatc gactgggtat ttttgcggat
    23821 tcaagtctcg tttatactct tcccatagtg aatctagatt ttcttttgta tattctttga
    23881 tttcgtttag tgcaggtaat tcgtaaactc tttttccttc gataaagata tcttgtaaaa
    23941 ctgggcgagc tgtaaagtct cgaacagttt tattgataaa cgtatgcact ggatggaaca
    24001 tgaagatagc ttcttcttct cgagggtctt catcccataa tgtcacgtag tctccttcag
    24061 atttcccatc aaaatttcga gtgatgcgcc acacttgttt tttccctgga gtagttactt
    24121 tttctgcatt gcttgataac ttgatcgtat ccatcatttt tccttcatca tcttcgatcg
    24181 atactagctt gaatactgca ccaagggctg gctgatcata ggctgtgatc aattttgtcc
    24241 caacacccca tacatcaatt ttagcttttt gcatctttaa attcaaaatc gttgcttcat
    24301 ccaagtcatt cgaagcatag atttttgctt ccgtaaatcc ggctgcatct aattgttccc
    24361 gaacacgctt agatatatag gccatatctc cactgtcgat gcgtacgcct tggaagttga
    24421 ttttgtcacc taattctttc gccacgcgaa tcgcacttgg cacacctgat ttcaacgtat
    24481 cataagtgtc gactaagaac acgcagtctt tatgggtttt agcgtaggcc ataaatgctt
    24541 cataatcatt tccataagat tggactaacg aatgagcatg ggtcccgcta gctggtatcc
    24601 caaatatctt cccagcacgt acattgcttg ttgcatctgc tccgccgata tatgccgctc
    24661 tagttcccca gactgctgca tccagttctt gtgcccgtct agttccaaat tccaatagtg
    24721 gatcttctcc gatgacagat ttgatacgag ctgcttttgt cgcgatcaac gtttggaaat
    24781 tgaccatatt caacagtgct gtttctacta attggcagtg cgctaaaggc ccttccactt
    24841 ggattaatgg ttcatttgca aaaactagtt ctccttcacg agcagaacga actgttgctt
    24901 taaattcaaa attttgtaaa tactccaaaa aaccttcagg atagacttct aatccacgca
    24961 agtaagcaat atcggaatca ttgaacgtca gattctctaa ataattgact aaccgttcca
    25021 atcctgcaaa aaccgcgtat ccgtggttaa aaggcatttc tcgaaagtaa cattcaaaaa
    25081 cagcatgtaa atcagctcga cctaattccc agtatgtctg catcatattg atttgatata
    25141 gatccgtatg cagcgtcaaa ctgtcgtctg ggtaagtatt attcatcttg tattactcct
    25201 cttggcaagt tttcatttcc tacccattat aacaaaaaaa attaatagga aaagaaatct
    25261 tccatttttt ctgaaaaagc acatgtttta cggatatttc ttgctaaaaa tgaactccat
    25321 ctgctaaaac tatcctttct tattggtatt taacctaaac gagaaagaat acttatttta
    25381 ttcaatgtat ccgagacacg aagaaattag cgttttctat ttttcttact tgataaaata
    25441 agtagatttt cctactacaa tcgtagccgt taagataccg atgattgaac aaatataacc
    25501 aaatgtctct acaacataat caatggcaaa agtttttgaa gcaataatac gtctttcctt
    25561 ttttgcttct tatccccaaa gaaacggata taacttatta tgtattgaat ttttttggaa
    25621 aggcgaatta tgacaagata taccttgcgt tgaaaaaact cgcggaaaaa atatcacacg
    25681 tttttaaaaa gatacaaagt aagaaagcag ctgtcaatag aatggaaaca aaaatggcga
    25741 gacatcaatc agtctcgcct tgttttttat tgtatacatt agatatggag caggttacca
    25801 taaagatgat tattagtcgt tattaaatag aatccttcgt atttttttgt tctatcacta
    25861 caatatcttt atttggacgt ttgaattgta ttccggcacg ttctagctcc tgtttcactc
    25921 ctacatggac tttgacatct tctcgtgtca tttttaaaac gtgatgaatc gcatagtcga
    25981 tttcttgcct tgtgattttt ttcttcgtat tgatcatcac gacttgcttt ttatcatatg
    26041 tgtctaccaa tagcagttgt gttcgatcta acgaaaataa tttgtaataa ttaatagccg
    26101 tattcccaaa aaagaattcc actactttag gataaaatgt cttaatattt aaattactat
    26161 tcacaggtgt ttcgattagc ttcatctcat tcctcttttc tatatagtcg atttagatcc
    26221 aatcttaagt tatgttacca tctttcctag cattaaggaa tcggttacaa ttgaaccttt
    26281 aaagacaaaa ggatttacct tttatcactt aatagtataa cataatttcg tgagaaaaaa
    26341 atacaatttt ttcttgacca tctcgttacg taaaggatta tgcttacatt tgtcaggagg
    26401 aaaaataatg gagtacacaa taaagaaaat gtcagagata tcaggagtca gtccgagaac
    26461 cttgcgcttt tatgatgaga ttggactgct aaaaccagct aggatcaatt cttcaggtta
    26521 tcggatttat ggcaaaaaag aagtcgatcg tctgcaacac atcttatttt atcgaacaat
    26581 ggcattcaag ttggatgata tccaagaggt cttagacaat ccatcttttg accaccagaa
    26641 agctttaatc aagcatcagc aaatgttgct ggaaaaacgg gcacaaatcg ataccctctt
    26701 gacaactgtc caacagacac ttgatatgta cgaaggagga agaaaaatga gtgacaaaga
    26761 aaaatttgaa gggtttaaac aacaaaagtt gaaagaaaat gaagaatcct atggacaaga
    26821 gattcgacaa aaatacggaa aaaaaaaggt tacagcatcc aatgaaaaat ggatgaatat
    26881 ggataaagaa acgtatgaag aaatgcaaac tgttgaaaag cagatgttat ttgatctcac
    26941 tctttactta aaagaaccag aagatgaaag cttagcagac cgtatcttcc aagctcataa
    27001 gaagtggttc tcttacagct ggcctgaata tcagccaaaa gcgcataaag gactaggaat
    27061 gatgtacgaa gccgatgaac ggttcactgc atattatgac gagcgaagtg gtcatggtgc
    27121 agcaaaagct ttaaatgaaa ttatccaaaa aaaggcgtaa tcttttacat gatccaacaa
    27181 aaaagtacac gtaaaatgac ctaataacaa aacagcagac acccaagtta gatttttatg
    27241 ctaacttttg gtgtctgctc cattctttca caagtttttt catcctactt taaatatatt
    27301 catcgttgaa taaacgtata aggtattttc actttatcct ttttttctgt aagaaacaat
    27361 tgaaatgcca tttctccgca agcttccaga tggtggtcga tggttgggaa accaagaagc
    27421 tcgctgatca gcaaattatc gcgtccaatc accactggtg tcttatcttg cagatagctt
    27481 tgcaagatgc ctgctgcaac catatccgaa tttgtaaaga caccatcaac tccaagctct
    27541 ttaaaaaaga agcctgcttg ttttcctttc tctgcatcta tacaatccca aaaaacaagt
    27601 gattcatcaa aagatggaaa aagttgatga catagctgca aagtgatttt tgagttataa
    27661 cttagcctgc cacttcgccc caacgtgatg cccaattgct ttataccttg ctgcttcaaa
    27721 taagtaagac cttctgtaat tgattgttct cgatcaataa agacacagct tgcctgtttt
    27781 cccttgattt cttcacaaaa aactagaggt ccatattttt gatatgccaa taaatcatct
    27841 agtgtattgg cacgagacgt aatgatcaat ccatcgaaag ctttagctgc aaattcttca
    27901 agataccttc gctctttttc tttatgatag cccgtcggta aaagtgtcac tttgtaatca
    27961 taatcaaacg ctgcttcaat gatcccactg atcaactgat caaaatacgg atgattggta
    28021 taaggcagaa tcactccaat gcttttcgtt tttccataac ttaactgtct ggcatttgca
    28081 ttagggatat aatcgacttc tttcatgacc gcaagtattt ctttcctttt ttcctcatct
    28141 acatatggat gtccattgat tacacgtgaa atagtagaaa ctgaataacc tgtgagcttt
    28201 gcgatatctc gaatgtttgc cactgctgct tcgccaccta tacaaaaaga ttttcttgta
    28261 aatagtctac cacagctgga ccgcattcaa aaaactgata catttttcct tcatgcgaaa
    28321 aactgatccg ctgcccgccc caatatatat cttttgtcaa attttcgatt tcattcattg
    28381 gtatttcttt tactatattc ctattcaacc cttgaaaact gtacaacgtt aatacggatc
    28441 ccttgaactc gacaaacgca taaaaataat tgttcgttgt gccatctgtt atctctacat
    28501 aagtattcat tgcaagccct ccttttgata ctttgagtat agtgtatgaa acgcgtctca
    28561 tagcaaggag tttgttttgc caaagaaaag ttttattcct ctttcattat taccaaagtc
    28621 tcttatttta aattgaatac attataatga tactgtaaat atatctttat tattagtgaa
    28681 tg
//
LOCUS       DARPZF010000030        27634 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.031, whole genome shotgun sequence.
ACCESSION   DARPZF010000030 DARPZF010000000
VERSION     DARPZF010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27634
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.031"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            119..766
                     /locus_tag="SLE65_001703"
     CDS             119..766
                     /locus_tag="SLE65_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEI8448997.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            850..1794
                     /locus_tag="SLE65_001704"
     CDS             850..1794
                     /locus_tag="SLE65_001704"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEI8448998.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            1929..3380
                     /locus_tag="SLE65_001705"
     CDS             1929..3380
                     /locus_tag="SLE65_001705"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEI8448999.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            3401..4237
                     /locus_tag="SLE65_001706"
     CDS             3401..4237
                     /locus_tag="SLE65_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEI8449000.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            4237..4896
                     /locus_tag="SLE65_001707"
     CDS             4237..4896
                     /locus_tag="SLE65_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEI8449001.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            5022..5711
                     /locus_tag="SLE65_001708"
     CDS             5022..5711
                     /locus_tag="SLE65_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449002.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            5717..6673
                     /locus_tag="SLE65_001709"
     CDS             5717..6673
                     /locus_tag="SLE65_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HEI8449003.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            6717..7229
                     /locus_tag="SLE65_001710"
     CDS             6717..7229
                     /locus_tag="SLE65_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8449004.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(7485..8033)
                     /locus_tag="SLE65_001711"
     CDS             complement(7485..8033)
                     /locus_tag="SLE65_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEI8449005.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(8122..9303)
                     /locus_tag="SLE65_001712"
     CDS             complement(8122..9303)
                     /locus_tag="SLE65_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HEI8449006.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(9539..11047)
                     /locus_tag="SLE65_001713"
     CDS             complement(9539..11047)
                     /locus_tag="SLE65_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEI8449007.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            11206..11397
                     /locus_tag="SLE65_001714"
     CDS             11206..11397
                     /locus_tag="SLE65_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449008.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            11600..12517
                     /locus_tag="SLE65_001715"
     CDS             11600..12517
                     /locus_tag="SLE65_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HEI8449009.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            12510..13583
                     /locus_tag="SLE65_001716"
     CDS             12510..13583
                     /locus_tag="SLE65_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449010.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            13731..14249
                     /locus_tag="SLE65_001717"
     CDS             13731..14249
                     /locus_tag="SLE65_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449011.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            14230..14622
                     /locus_tag="SLE65_001718"
     CDS             14230..14622
                     /locus_tag="SLE65_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HEI8449012.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            14698..15633
                     /locus_tag="SLE65_001719"
     CDS             14698..15633
                     /locus_tag="SLE65_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HEI8449013.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            15766..16545
                     /locus_tag="SLE65_001720"
     CDS             15766..16545
                     /locus_tag="SLE65_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEI8449014.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            16538..16855
                     /locus_tag="SLE65_001721"
     CDS             16538..16855
                     /locus_tag="SLE65_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEI8449015.1"
                     /translation="MTKLYLLLLVVCLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            17099..18709
                     /locus_tag="SLE65_001722"
     CDS             17099..18709
                     /locus_tag="SLE65_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEI8449016.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            18866..19714
                     /locus_tag="SLE65_001723"
     CDS             18866..19714
                     /locus_tag="SLE65_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEI8449017.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            19945..20424
                     /locus_tag="SLE65_001724"
     CDS             19945..20424
                     /locus_tag="SLE65_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449018.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            20457..22685
                     /locus_tag="SLE65_001725"
     CDS             20457..22685
                     /locus_tag="SLE65_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEI8449019.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            22814..24457
                     /locus_tag="SLE65_001726"
     CDS             22814..24457
                     /locus_tag="SLE65_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEI8449020.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKINK"
     gene            complement(24530..25075)
                     /locus_tag="SLE65_001727"
     CDS             complement(24530..25075)
                     /locus_tag="SLE65_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEI8449021.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(25098..25583)
                     /locus_tag="SLE65_001728"
     CDS             complement(25098..25583)
                     /locus_tag="SLE65_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEI8449022.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(25573..26385)
                     /locus_tag="SLE65_001729"
     CDS             complement(25573..26385)
                     /locus_tag="SLE65_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HEI8449023.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(26524..>27634)
                     /locus_tag="SLE65_001730"
     CDS             complement(26524..>27634)
                     /locus_tag="SLE65_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HEI8449024.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT         9049 a         5026 c         5526 g         8033 t
ORIGIN      
        1 tttttcttta tattttcata ataaaagttt ggttctttaa tttttaaaca tgacagaaaa
       61 ttttttcttc gttatacttg taatagaata ctattttata acaaagggga tcgaatcaat
      121 gaaaaaaact gttatttata ctagtttatt tgcagctttg tttttagctg cttgtcaatc
      181 aaataccaat caaggcacat ctgggaatac gtcttccagt agcgaacagc gctcttcaca
      241 ggtatcggac tcctcaacaa aagcaagcac atcttcgtct agccagacaa aaagttctag
      301 tgaagcaagt actcagtcag atatcaaagt gtctgcagct cgtgcgatcg aattgttcca
      361 agataaatac ccagatactg caattactag tttggaatta gatagtgatt ggggatctta
      421 cttctacaag atagaaggtg tcgatgatca aaaagaatac gaagcaagaa ttgatgctca
      481 aaatgaaaaa atggagacag agaatccaga aactctagat cgagatgaac aaaatggtca
      541 aaagaaaaaa gaagatggtc tggatgttga taaattgatc acgattgagg aagcagcaaa
      601 aatcgccgtc gacaaagtag gaagcggtac ggcaacagat tgggatttgg ataaagattt
      661 aggtactact tattgggaag tcaaagtaaa agacggcaat caaagtacat cagtcaagat
      721 caatagccaa acaggcgaag tactgtcaac tgaacaagat gattaagaat ttcttcggaa
      781 aacaagagtt gatttttctt ttagtcatga tacactagac aaaataactt gtttgaagga
      841 gcgatttact tgagtttaga aacgaccttt gccaatcata tctttgccaa tcctttgatg
      901 aatgcatctg gtgtccactg catgactacc caggaattag atgaactggc tcattcagaa
      961 gcaggagcat ttatcactaa gagctgtacg atcaatgaac gaaaaggaaa tcccgaacca
     1021 cgctattttg atgttccttt agggagtatc aattctatgg gacttccaaa cttaggtttt
     1081 tcttattatc tagagtatgc tcttgcgtat gaaaaagtgc aggaaaacca aaatcaaccg
     1141 ttattttttt ccattgccgg gatgagtgtc caggaaaact tggaaatgct tgagaaaata
     1201 gaaaaaagtg ggtttaatgg gatcactgaa ttaaatttat cttgtcccaa tgtgcctgga
     1261 aaaccacaac tagcttacga ttttgaggcc acttatgaaa cactgaaaga agtattcagc
     1321 atcttttcta agccgctagg aatcaaattg cctccttatt ttgattttgc tcattttgat
     1381 cagatggctg atatcttgaa tcagtttcca ttgacctatg tcaatgctat caacagtgtg
     1441 ggcaatggtt tgtatatcga tacagaacaa gaagcagtag tcatcaaacc aaaagaaggg
     1501 ttcggcggca ttggcggaga gtatatcaag ccgactgctt tggcgaatgt tcgcgctttt
     1561 tatacacgtt tgaaaccaga aatccaaatc attggtacag gtgggattcg gacaggacaa
     1621 gatgcatttg aacatctgct atgtggcgca agcatgttac agattggtac cgagcttcat
     1681 aaagaagggc cggaaatttt ttctagaatc ataaaagaat taacgcagat tatgtcagaa
     1741 aaaggatata cgtcaattga cgaatttaaa ggcaaattac gcaccatttc atagcaaaga
     1801 gacgaaggtc atgattgatc ttcgtctttt tttataaaaa acactcgtct gttcattcct
     1861 gtgcaagcgt actcattgta tgttagacga acttgtggga aaataacaga ggcaaaaagg
     1921 aggataatat gaatgatgca acagaattag caaaagagct taaagaaaaa gaatttagtt
     1981 ttcaagaact agttacggat atacagaaaa aaataaagaa gcaaaatcat gaattgaatg
     2041 cgtttgtcgc gcttgaacca ttcgagagta attcccacga gctattgatt ccccagtcag
     2101 aaaaagggcc attggctggt atcccatttc ctttaaaaat gctcggtcaa gaaaaaaagg
     2161 gatggctagc tacttcagga tctcgtttat ttgaaacaca ccgagcttct catacatcta
     2221 attatgtgcg gcaagcagaa gcgataggtc tagttccttt tggacaaacc aatgcgccag
     2281 agtttggttt caaaaatatt acagacccag tcatctatgg cccagcaaga aacccttgga
     2341 accttgaatg tacaccgggc ggatcaagtg gaggagctgc tgctgcagtt tcatcaggaa
     2401 tcgttccttt agctggtgct agtgatggcg gtggttctat tagaataccc gcttcgtttt
     2461 gcggattgat tgggctgaaa ccttcgcgag ggacgatgcc agttggtcca tatgcttgga
     2521 gaggatggca aggagctgct attgatttcg gcttgacagt ttctatgaga gacacggagg
     2581 ctttatttta tgggatgaga agtatccatt ccggtgcgcc atatcaagta tcgccagttg
     2641 agtggcaaac acatccaaga aaaaaacggt tgaagatagc tttttgtgtt gattcaccga
     2701 tccactcaca gattagtgaa gaggcagtac ttgctgtaaa aaaagctgta gatttccttg
     2761 gaaaagaagg gcatgatttg acagagattc cttacccact agatggtcgt aaactgatca
     2821 cgtcttatta tcagatgaat ggcgcagaaa cagcagcaat gatccgctcg attgaaacag
     2881 gcatccagcg agctgtcaga aaagaagaac ttgaacccat ttcttggact ttgttccaat
     2941 atggtcagaa gctctctgcc gctacttaca tcgattctct gcatgtatgg gatgaagcag
     3001 caattgtcat ggaaaaccta catcaagaat acgatctatt cctttcacca acgactgcat
     3061 ttaccgcccc taaaatcagc gaagatttgc aaagtgatgc gataagagca cagatggaac
     3121 acatcagtga ttgttctgaa gtagaaggtt tagacgttgt ttcttccatg tttgaggaga
     3181 gcttgaagat cacaccttat acacagttgg ctaatctgac tggacaacca gcaatcagct
     3241 tgcctactca tttgacaaaa gaaaacatgc ctctaggaat ccaatttatg gctgccagag
     3301 gaagagaaga tttgctattt caaatcggct atctatttga agcaaatcat cagttccatt
     3361 taccaaatcc atggaaatag cagaaacaag gagaagaaga atgaagaaaa aaagattgtt
     3421 tgctctaata actagtgcct tttttatttt aagcgcttgc ggtacagctg ccgctaatca
     3481 ggaagataac agctggagta atgtagaaaa aaagaaagaa ttagtagtag cgacttctgg
     3541 cacactgttt cccgcatctt attataatga tcaaaatgaa ttagttggtt atgatgtaga
     3601 tttggcaaaa gaggtggcta aacggttaaa tgtcaaaatc tcctttaaag aatacaacgt
     3661 ggatggacaa atcacttctg tttcaaaaag agaatcagat tttgctgcga acgattttgg
     3721 tatcacaaaa gaaagagaaa aaaaattctc cctttcagag actttcaaat attcatttga
     3781 cagtatgatc gtacgaaaaa aagatgattc aggaatccac tcacttgaag atcttaaagg
     3841 gaaaaaagca gctggcgaac ccaatactag ctatatgcgt ttagcggaaa aacacggagc
     3901 taaattagtc acatatgaca atgccacgaa tgatcagtat ttaagcgatg tagcaaatgg
     3961 tcgaacagat gttattctaa atgattatta tctgcagaaa atggccgtat ctgctttacc
     4021 agatatccct gtaaaaatac tggagaacgt ttatttcaat gaaaacgaaa gtggtttttt
     4081 attgaaagaa ggaaatgatg ctctgaaaaa gaaaatcgat ggcgtattaa aagagatgaa
     4141 agaagatggg acgacaaaga aaatatctga aaaatatttt caaactgatg tttcagtcaa
     4201 accgaaagaa acgatggctg agtcggtgag tgagtgatgt actttcctct aattgatttt
     4261 tccctcatgt ggacttcact tcctttcgta ctgcaaggct tggtatacac attagggatt
     4321 ggcttcgtgt cgtttctttt aggaaatctg gtagggttgc ttttgacagt tttaggtctt
     4381 ttggattggc tgcctctgaa tgtatttatt cgtttttatt tatcgttctt tagaggcatt
     4441 cccgcactag tcctgctgtt tctgttatat tttgggttac cttatcaatt aagtgcctta
     4501 acggcttcag tcatctgctt tacgattacc agcagtgcat ttattggtga aatctatcga
     4561 ggatcactag caggcgtttc ttcaggtcag tgggacgctg gtttagcttc tggtttttct
     4621 ttctttgggg tattgaaata tatcgttttg ccgcaagctt ttcgaatctc agtaccggca
     4681 ctcagtaacg tagctatgga tctagtgaaa ggtacttcgt tagcagcaac aatcacagtg
     4741 ccagaaatat ttcaaaaagc aaagatcata ggcggtcgga cattcgatta tttttctctc
     4801 tatattttag ttgcactgat ttattgggtc atttgtatcg ggatcgaaaa agtgcaacag
     4861 tatttagaaa aacgttctat gcatcagtca atctgaaaaa tagaaatggt gctagcgtgg
     4921 ctggcaccat ttctattttt tgtttcttgt atattctgcc tagtatttta aaaccatttc
     4981 atgtaaaatg taaatcgaaa atatgttcgg aggtagaaaa catgaagacc ccgctaacca
     5041 tcgaaataga atcctcgtta taccaatatt gcatcgagca aggcggcttg gttgtagaag
     5101 aagtcacgat gcctgatgac caaggaattg tagatacgct tagctgcttg acaaaatttg
     5161 atggaagccg agaatggcga tgctatgagc tgaaagtgac aaaagcagat tttcgctcta
     5221 cagccaaact gtcatttgtt ggacattata attattttgt tttaccaagt aaactatatg
     5281 aagaagtaaa aactgaaatc cctacaggaa taggtgtttt agtgtatcgt ccgtacacgg
     5341 ttgaagagga gatgcctgcc tctggtacat ttctgattgc gaaaaaagca gcaaagaaag
     5401 agcttgctgt accggaagaa gctttgacaa accgcttcat ggcttcttta ttcagggaag
     5461 taagaaaagc aaagcaaatg gagcgaggcg taaaatattt tccaacagat caattgtaca
     5521 aagaattgaa aagacgttca gaaaatcaag atccattttc taacgaacga tattatgaac
     5581 ggtttttaga ggaaatagct agtcaggcaa tcaatgagtt gcaagaagaa gttatcgcgc
     5641 ttcagcatga ttatgaatat ttgaggcaac aacagcagat ccgtcggttg cctacagagc
     5701 cattggagtg aaaaatatgt actatcctta tttaagagga aaacaatttg acctattagc
     5761 attaaaagaa gcactgtcgc gaggattgct ctccaataaa atccaaccag tgatcgaacc
     5821 agtacgtgat tccgctacgc ttaaaaatgt gatcgaatta tttcaaaaaa agcaccatcg
     5881 aatcgctgtg atccaaaatc cccaagtagg acaattcaaa ttattcgatc agcatgtgca
     5941 cagttggaca gtcaaagaaa atagctctgt cgtccctgca cagatcttaa cgccagaaaa
     6001 tctcagtgaa gtactggatt cacctccagc gtttcttgtt ttcgatggac agcactaccc
     6061 aaaagataca gaggtgtgga aacagttggc aggagttgat tcgaaatttt tgataccaga
     6121 tactagtcgc tttcgcatct ggctgcccga aaacaaaatt gtgatccgtg actcttttca
     6181 aacgagaaag catgttgaaa gttatgcaga taaaacagat gactttttta gtgatgacta
     6241 tctttttttc cacgcagacg gatatattgg attttctgat ttcacgatcg aaggtagccg
     6301 ttatttcgat aaagggttcc ctagccgagc gcttgctatc catctaacgt atattgatgc
     6361 ttacggcaat atacgcgtga aacattttgt ctctgacagt aacgactctg ctaaagacca
     6421 agcattgaag tttcttgaag caggagataa aatgaaaaaa tggatcatgc gtcaccatca
     6481 tcaactcttg attacttcag gaatgattga attattggct ctttaccagc aacaaaaatt
     6541 ccctggactg ggagtgttga aaaagtggtc acttatgcat catttggaac ttattagtca
     6601 cctgctagat catccaaaag attggcttaa atattattca aaagttcagg aactatatga
     6661 agtgatccaa tgattagata atgtaaatga aaaaggaata gaaaagagga aactggatgt
     6721 atattcggca aacaaggaaa gaagaagtag aagaagtggt agaaatcatt aatgccgcag
     6781 cggatttcat tgcttcgcaa ggctctcctc aatggcaaaa cgggcagaaa ccaacaaaag
     6841 aaacgatttt gaacgatatt gaaagaaaag aaagctatgt attaatagtg gaagatcaaa
     6901 ttgctggaac agctgcatta gtctcaagcg tggatcccgt ttacacaaaa atagatggta
     6961 gttggaaaga atcaactggt ccttatttat cgattcatcg tgtcgcttta gcagaaagta
     7021 ctcgaggaaa aaaactagca aaaccgttct tagaacattt gttgacgatt gcagccagca
     7081 aaaatatcca agatatccgt atcgatactt atccagctaa tgaaccgatg gaaaagacca
     7141 tctattctgc tggattcact tatcaaggga tgattgaatt tccttttgaa cacggcgaaa
     7201 gaaaagcata tcaaataatc atcaattgac tataaaatca tctgagcaaa gataaagaca
     7261 ttaacactac tgaaaaaaac aatcatatga tagccaagag gttgtaacag aagtggccag
     7321 cttcaaaaaa caagaaagaa tttccgaaaa tgcttctcaa atttttgtgg aattttagcg
     7381 tattttacga aatagctgct ttctgaaact cccttcatcg agaggtcgtg acatagcttt
     7441 tgtcacgacc tctcggctta tcctacgagt attattcgat acatttatat caataatcct
     7501 ttttttattt tatctgcagc ttcttggaac gctccatcgt ttgacacgac taaaagtgag
     7561 gggatagctt tcaaacgttt caactgtgct aaatcttcta cataaaccgc cagtctggct
     7621 gaaatctgtt cagatgaatc tccacgtttt ttcaggcgcg attgcaatgt ttctttagag
     7681 atcgtaataa agataggacg gactaccgtc ccgaaatact catataaatg ccaaaaacca
     7741 tttgctgtca aaacggcgta acaatttcct actgtcagtt tctttttaat ttctgcttta
     7801 ctggaaccat atttatgttg agcatattgg tcccactctg caaactcatt tcccttgatc
     7861 atctgattga atgtattgtc agaaacaaaa taataatcct cttgatcttt ttccccaggt
     7921 cttggtgatc gattcgtgta agtaatgatc ttttgttccg gctgaaaaat agcttctgcg
     7981 agtgaagttt ttccagaacc agaaggaccg ataaatacat agcaataatt cattgtcatt
     8041 tctcctttga tgattgaaca agtgaaaaag ctttggaaaa tatttccaaa gcttttaaaa
     8101 gtaactttgc ttttttgtat attataccag caagccagtc acaatagcac ttaaaaagct
     8161 gactaaagtc gctgttagca aaattttcaa tccgtgtttt gcgacaagat ttcctttttc
     8221 ttcatttaat cccttcatcg caccagaaat gatcccgata gaagagaagt tggcaaatga
     8281 aacgaggaag acagatataa ttgctgttgt acgctcagta aaatggaaat taccatttgc
     8341 taattctgtc atagcaacaa attcatttgt aaccagttta gtcgccatga tactaccggc
     8401 atccactgct tctttccatg ggattccgct gatgaaggca agaggggcaa agatgtaacc
     8461 taggatctct tggaaagtga tgccgaatat cccgtggaag atagcattga tcatggcaat
     8521 caaagcaaca aaaccgataa gcatagcagc aaccgtgatc gccacatgga aaccatcaag
     8581 aatgtattct cccaacattt ggaaaaatgt ctgttctttg ttttcttcaa tgatcagctc
     8641 atcttctttt tcttctaata catagggatt tacaattgaa gccagaatat aaccgccaaa
     8701 taagttcaaa acaagggcag tgatcacata tttagaatcg atcagtgcca tataagatcc
     8761 gacgatcgac atagaaactg tagacatagc cgatacactc atggtgaaca aacgtttctc
     8821 agataggaag ggtaattcct tttttatgga aataaaaact tccgattgtc ctaaaatagc
     8881 agaagctact ccattataag attccaattt gcccatcccg ttgattttac ttaatcctag
     8941 accaacagct ttcataaata atggaagaat cttgatatag cgtagaatac cgataatagc
     9001 agaaataaat acaattggca tcaatacgga aagaaagaaa ggtgcacttc ctttatttgc
     9061 tacaccggca aaaacaaagt caacaccttg cccagcaaaa gcaagaagat gatcaaacat
     9121 ttttgccaat acagaaacaa ccgctgtacc aaaagttgta cgtaataata cgaaaccaag
     9181 aacaagctgt aaaacgaaca tcacaattag tggtttcaat ttgattgctt ttttgttact
     9241 gctgatcaaa aaagcaagcc ctaatgtgac aaataaacca ataataccta ataaataact
     9301 caaataatca ctcctattcc aaattccgtt ttattttacc tgttttgcaa ataaaatact
     9361 aatctttagt gaaattttca ttactttttt agagtgaaac gcattcattt tccattagaa
     9421 aataaagcga acaaaataaa aggtttaaaa agtgtaacgt cttagtaaag tctataaaaa
     9481 aacgaaacta tcgattaagc taatagtttc gttttcaaca tttataagta aactttttct
     9541 attggtaata tagattttcg gaagggtaga caggtgcgca ggtaatatcg attcctagtt
     9601 ttttcaatgt ttgttcatca tttttattga ccatcacagt agagtgggct tgtgctccct
     9661 caagttcagc tagtttatca taagcaactt gagcgattgg attcgttact gcactgattg
     9721 ataaagcgat caagacttca ttgatgctta gtgcatccaa agaggaatga agtgtctttg
     9781 atttcaatcc ttgtattgtt tcaagaacta atggtgacaa taaaggaatg tcatctgcga
     9841 tatgggctaa atgttttact gcatttaaga taactgccgc tgacgcatcc atcaatgaac
     9901 ttgtacgccc ggtaatgatg acttcatctg gtaattcgat tgcaatcaca gcagaaggat
     9961 cttttgtagg actttgcgct tgaatcttat ctgcatagtc atgggcaggg actaccacgt
    10021 ttcggtcttc aggacgtaaa ccgacttctt ccataatcag tttgattcga ttaactgctt
    10081 cttcgtcgat caatcctttt ttgaagtcgc attctgtttg gaaataacga cggatgattt
    10141 cttgtttaga ggcttcttgg acaacggtat catccacgat cccaaatcct acacgattca
    10201 cacccatgtc agtaggagat tgataaacag attctttacc agtaattttt tcaataatac
    10261 gtttgattac aggaaatgtc tcaacatccc gattatagtt cacagctact ttattgtagg
    10321 catcaaagtg gaaggaatcg atcatattga catcttttag atcgactgtg gctgcttcat
    10381 aagcaatgtt cagcggatgt ttcaacggaa cattccatac tgggaaagtt tcgaacttgg
    10441 agtaaccagc tgcatgtcct ttttggcttt catgatacag ttggttcaag gaagtagcga
    10501 gctttccact tcctgggcca ggagctgtca ctacaacgat tggtttagtt gtttcaatat
    10561 actcattttt tccaaaacca tcttctgaga cgattttttc tacgttgact ggatagtctt
    10621 cgatttctga gtgtttatag accttgatgt ttcgtctttc tagtttattg ataaagactt
    10681 tcgtggcagg ctgtccacta tagcgagtga taacgacact gttgattaat aagccataac
    10741 cacgtaattc atcgattaac cgcaagatat ccatatcata agtaatccca taatcaccac
    10801 ggatcttatt acgttcaata tctccagcat agacgcaaat cagtatttca gcttgatctt
    10861 tcaatttttg cagcaatttg attttcgcat cttcttcaaa tcctggaagt acacgtttcg
    10921 catgcttgtc gtcaactagc ttcccaccaa attctaaata taatttgtca tagtggttca
    10981 ctcgttccaa aatatacgct gactgctctt caatatattt ttctgaatca aaaccaattt
    11041 ttttcactag gttccctcct taagtactaa agcatttttt catttttttg aggattcgtc
    11101 aactggaaga gcgaaattcc tcaaaaaaac aaagaaaatg gtttaaacca acttgtctag
    11161 atagttattc attggtatga tagtttttga taaggaaggt gctacatgaa aaaaagacag
    11221 aaaaagaaaa acgcatataa acactatatc cgttcgattt ttaccggtta tgaaagaatg
    11281 cttgaagatc ccgaattgga acaattgacg tttacttatc taaacgaaga aacgcagcta
    11341 actcgtgatg agcatcagcg cattcatttc acaacaagag atctgcctag taaataaaaa
    11401 ataagataaa ggtcatcgga ttcgattctg tcctatcaga tggaaagact agttgatcga
    11461 aaaaaaggct gtaccaaatt ttggtgcagc ctgttttatg gagcattgcc cgctcttttt
    11521 tataacaatt ttttacagaa aatggtacta ttgaagtatt aataagtgaa aaacagatga
    11581 gtaagaggag gcaagtagta tgaaagagcc agatacaaat gcaaattatg agccagacga
    11641 actagaggag acgaatgcgg atcaggatac aggacaagaa tcgtcttctt tttacgatat
    11701 caaagaaaaa gcaagcatga atctttccca attattagaa gacttacagg cttttgaaaa
    11761 agctgtccgc gaagaagata tccctgagat ctaccgttta tacaatggcc gattgaatga
    11821 agaattaaaa agaagctcaa atgaaaatca cgagatcgat caattgctga tgcgtaagat
    11881 ccatgatcgt tttttacagg aatttccttt tatggaacaa gtagaaaaca tctcgccaac
    11941 gatgagctat tacaaaatcg gcacttatta ccatgatcgg cccacggtcg gtattgatgc
    12001 aagtctgcca gaaatttttg ttttgcctaa gatcgatgaa gagtgggaga aatattccca
    12061 accggagtca acggactatg acaaaaaaat caatgagcta gacgcaaagg tgatcactgc
    12121 tcagacagaa attgaacgtt tagatgaaca aataaaagaa atcaatcgac aaatgactga
    12181 tttgaacgac aataaaggat tcttgaatcg taaaaaaatc gaggaagaaa ttcaagaatt
    12241 agagaagaag aagcaagtac tatctaatga aaaattaggc tggcttcctt atattgagac
    12301 gcctgaaaca atccagcagc aaaaagaagc attgaagcaa gaagcaagag cagaccagct
    12361 tcgtgcagcc atcgtagaaa aagaacaaag gcaaatcaga cgctatttcg gtagcaaaga
    12421 gggattcggt caagcaatcc atgaattctt gatgaattat cttggcaatg agaatcctaa
    12481 taatcaatct aatgaaggag gttccgagta tgaatgaaca cgatgaagca gaatggacaa
    12541 aaaatgaaga acaaacagaa gatcatgaag aaacgaacac ttcattggaa gaacaaacaa
    12601 gtaatcctct ggatgacaca gaagaaatcc ctatgctaga ggaaacaaaa atacacgaaa
    12661 aagaaaaagt aactccgacg aatacgaata ctgcagaaaa cacccatgct tacgaaataa
    12721 ctgaaaatcc cgggtattta gaaggaaaag agcaagatca tcaagatatc gtcagtttga
    12781 ttgaaacagc ggaagcagaa ttagcggatt tacgtatgag aaaagatttg atcgaatcag
    12841 attttccaca attattagaa tcatatgatc gttttatatt gaatgaagaa ccaatctcca
    12901 cgatcggaaa gacaagcctg atcgaatact tcacgtatga attactgaaa ccgttgaatg
    12961 atattggtct ggaacggtca aattcagctt atgacacatg gaaaacaaga catttttcga
    13021 tcaattatac gttgaatgga caaaacgaat tagtcttttc ctttgtatta ccgaccatcg
    13081 atcaacgata ccaagtggaa tcgatgagtc tcctaaacgt atcaccagag acaatggaaa
    13141 tcaatgtcca agatgaccgg gtgctttctt tgatccgaca ctggtcagtg gatcgagtat
    13201 tctctgcagg gcagatcacg atattcaatc acaaattgaa tcaattatta gcccatgcaa
    13261 gaacacttgg ttttaccgtt aatcagacat tactagacaa tacgaagcca cttcgtttga
    13321 atcttcagag cgaatttgaa ttgacgaatg aagtattgga tgatattttt atcgtggcaa
    13381 tgaaaaatcc atcctacgat atggaaaaga tcaacgaaac tacttatcaa gtacgattag
    13441 ataaaggaca gtctttaacg ataacaacaa acgaaaaaga tcaaacagtc ttgtcgatct
    13501 catctggaga ctacccacga tctgtcattg atttctttat caattacgaa ttcttggtcc
    13561 cattaatggt gagaaagtcc tgattggata agttggatta ccagatgtca ttcagataat
    13621 tctgttccaa aggacttgcg gcagttatcc agaataattg tcacaagtct tttctgtatg
    13681 tactaaatgg acgtgaataa cttgctgatg aaggagggat ttcattagga atgtccacaa
    13741 ataaaatagc acagcttagc ttattgtctg ctgcttgtgt agcaggtagg atcgcttttc
    13801 aatttattcc gaatttccag ccaatgactg ctattttttt atttatagta ctttacttaa
    13861 gcttaaaaga tgcgttaatt gtcatgagtc tttctattgc gatcagcagt ttttattttg
    13921 gtgttggacc atgggtcatc ggccaatgga tcagctatac tgttgttctg agtttgtttt
    13981 caatcgtctg cttgagaaaa acagtgcaaa ggaatctatg gttaaaggga gtctgttttt
    14041 ttctggcggg catggtttac ggaataggta tgaccgtttt tgatacgctg ttatatcgtt
    14101 tgcctcaacc ttggatctat taccttcaag gggtgtcgtt tgatttgatg cacagtatag
    14161 gcaatgttgt gttctttctt gtttttctgc cagtcgtcaa acgtttttac aatcattcag
    14221 gaggaaaaaa tgaaaaaaat aatttatagt ttgcttgcaa tgagtgtcag tatactcatt
    14281 ttgacaagtt gcagtacaac ctatacacaa tcggcttcca accaaaagga ggaagtaaaa
    14341 acatcgcaaa aagcaacaat cacgttacaa gaaaatggtc aaaacttttc ggaaaaagaa
    14401 gtgttcttca aaaaaggcga tgatttactg agtattttga aacgaaattt tgaagtcaaa
    14461 gaagataacg gcttcatcac ttcgcttgaa gggcactcac aggatgagaa aaatcaactc
    14521 tattggatgt ttactgtgga cgggaaaagt gctactactg gtgccaaaga gatcaaattg
    14581 aatgatggac aatcggtcat tttcaatttg tctaaactat aagtttcata aaaaactgtt
    14641 aaagggcgaa tattgccata attcagtgag ttcagttgat gaaagaagga aaataacatg
    14701 gaaaatttta aaaaaagcgg aatgttttcc gtaattgctg ctctaggggc taatattcta
    14761 gttgctatca gcaaatttgt cggctatgca atcagtggca gtgccgccat gctaaacgaa
    14821 agcatccaca gtatcgttga ttgcagcaat cagattttgc tgttattcgg tgataaacaa
    14881 gccaataaag gacagagcga gttgcatcaa tttggtgaag gacgagcaaa atactttttc
    14941 agtacaatcg tcgcaatgat gcttttcttc ggcggtgggg cacttggggt gatggaagct
    15001 tttgaaaagt tgacgcatcc atcccatgaa gtgggtaatc cgatcattgt tatagcaata
    15061 ctgttatttg gtttggtaat cgaaggaagt tcgttacgcg tggcaatgaa agaaatcaaa
    15121 gaattgaata ctgaaaaact ttccacgatg cgctttttgc gcgaaagtcg acacagtgaa
    15181 atactgatta tttttacgga agacttgtgt gctgtaatcg gtttggtctt ggctttagca
    15241 ggaacaatat tgacttatgc aaccgggatt gctgcatttg atgcgatcag cggattgctg
    15301 atcggtttct tgctgatggg agccgccatt ttcctagcaa aagaatttta tagtctgatc
    15361 atcggtgaaa gcgtgacagc aagcgattta tcaaaaatca agttagcttt tgaacgtcct
    15421 gagatcagtc ggctgatcga tataaaaaca gttcatttaa gtccaacgga gattttagtt
    15481 gcagcaaaag cagatatcgt tggtaacaaa gagaatgaag cttactcggt catcaatgat
    15541 attgaaaaaa atatgcgtca gtctcttcct gacaagaaga tgtatatata cattgaaaca
    15601 gataaatatg acccaaatta ttctcgtaaa taaaacgttt attcatgaat tgaagcaaaa
    15661 atgagaaaaa tataatcttg tttttaaata aaacggctac aatttagcga atttatgtta
    15721 caatgagtcc gctgtttatt tgttgtaatt aaaggagata ttttaatgaa caaaaagaaa
    15781 agtgcgccat ggcttcaagc tttgcatgca gtgatgccac tttgtataag ctatatacca
    15841 gtaggattag cttgcggagt attgttgcaa aaagttggat ttgatcctct cttatcagga
    15901 ctgttatcga ttctggtctt ttccggtggc gcgcagtttt tagttgcatc tatgcttacg
    15961 acgcaagcat catttgcaac gacattattg atggttttct ttttagaatt acgctataca
    16021 ttattaggag caagtcttgc cggttttatg aaaaaagaaa agcggacgtt tttggctgtc
    16081 ttttctcaat cactgaatga tgaaaactat gcggtgaact acttaaagtt ttcaactgac
    16141 ccttcctgga ataaaagaaa ggctttatat gtcaattggt tctcaatgac tgcatgggcc
    16201 ggtagcaata tgatcggtaa ttttttcggc tcggtgattc gagtagatgc tgaccttgtc
    16261 cattttgctt tgacggccat gttcattttc atgtttatca tgcagatgaa aagcgcacta
    16321 ctgatcttta caggtttatt ctcaggcgta ttaggggtcg tattcatggt attattccaa
    16381 aatactttcg gattgattgc agcaacagtc attgcttcat ttgccggatt tatgctggag
    16441 aaggcattca aaaaagaaaa agctaagaaa ctaagagacc gcggtaaaga tgtcaatgag
    16501 ccgctcttca acttcccgga acaggaggcc aatcaccatg actaaactat atttgctact
    16561 tttagttgtt tgtctgttca tcgtggcata tatcccgcgc ttgttcccga tgctttattt
    16621 tactcatcga aaagtgccat cctggttcag tgactggatg aaatatgtac cggtggcatt
    16681 atttgcggcg ttagctttta aagatgtttt cattactcat gaacatctgg atattgcttg
    16741 gaatatcaaa atagctgcaa tgattctagt agcaggcgtg gcttacaaaa cacgttcgat
    16801 ggcgttgtca gttttgacag gacttgcgtc tgtctttttg ctgtctatgc tttaaactgt
    16861 tttattttat taaaaacaga gattgcgaca taagttgttc aaactgatct atccgaactg
    16921 catttgcaac agtcaattct ggatgcaagt ttattcgtag ggataaaaaa gattagtgtt
    16981 ggcttatgat gcaagctctt ttttatttta ggaattagag agggatttgt ccttctatga
    17041 ttttttgcta taatagggaa gatgtttatt ttatgaaaga atagttgagg gaatttaaat
    17101 gaataaaaaa ttgatgcaag gaacattttg gctaaccttt gctaatcttc tatgtaaagt
    17161 tttaggggta gtctatttga ttccctggct aagtatgatg gggaacaatc aagatggtat
    17221 gcttgctacg acattgtata atgttggcta tcttccttat ggattgttcc tgatgcttgg
    17281 tacagtcgga tttccaaatg cgattgcaaa aaaagtagct gtagccacaa aagaaggaga
    17341 taacgctgct tgtcggctga tttttagaag tacgatcaat atcatgtttg tcatcggtat
    17401 cgcctctgct gcactgatgt atttatttgc tcctttacta gccggaatca gtccgattgc
    17461 taacgttaat aatgggatac tagctatcag aagtttatgc ccatctttga ttgctatccc
    17521 aattcttagt gcaatgagag gatatttcca aggaaaaaat gatctgcggc cttatggaac
    17581 ttctttgatt atcgaacagg ctgtgcgagt gatcgttatc ttggctggta cttattactt
    17641 gcgcgtattg actgacggaa ccatattaga agctgtattg atcagtacag tcgcttcttt
    17701 cttcggtggg ttagctgcga ttatccatat gtatatcgtc ggacgcagaa aagacttctt
    17761 cgaacttaaa gattttttga tttccagccg ttatttcgaa agagaaaacc gatctgcctc
    17821 tgtctctatc attcgggaaa cactaccgtt tatttttgtc ggctcagtca ttactatcgt
    17881 tcaaatgatc gaccaagtaa cgatgaaacc actgcttcac tttttccgtc cagagatcgc
    17941 agatcagcaa ctggaattct tattcagccg tgcttctgtc aatccaaata aattgacatt
    18001 gatcctgatc tccatggtag gaacagtagc tataagcagc ttgccaatat taagcacgat
    18061 gaagaaaaaa gatcggatac aaatcgaaaa aacagtagga gatagttttt cgattgcgtt
    18121 attgattctt cttccttcat tgactggaat gtctttatta gctggaccac tatacacatt
    18181 gttttttggc tatgatcctg aaagtgtcgg atatttccaa atggctttgc tagcttcttt
    18241 gtttttctct ttattcacga tcctatctac gatgcttcaa tctttgaatc accatcgttt
    18301 tgcgatccga ttaactgtag aagcaattat cctgaaagtc atcttccaag taatcggatt
    18361 aggattagtt ggcggatacg ggatgagctt atcaaatggc ttagcattcg gtattgtctt
    18421 tgttcgcggc tatcacttta tgtgcaaaga ataccgaata gcacctttag caaagatcag
    18481 caattttttc ttaaaaactt tccgctccac cctgattatg cttgcagtat gttttgccgt
    18541 tttctttttg ctgaatcagc gattgtcaat ggaatcaaaa agctatgcaa tgatttattg
    18601 tgtggctgta ggaagtattg gcggcttagt atttttattt tctcaattcg gaaaaaatgg
    18661 gtttcgaatg ttgaaaaatg ttaaacatca tagcagaagc aaagaatagg ttaactaatc
    18721 gttttttgct gtcacttgaa aaacggcaac tcgtatgatt acgcttgtcg tttttctatt
    18781 ttccaatttt agtttcatat ctaatcttac ttatgatata gttataaggt ctggaaaaat
    18841 tctttgaaac gaggaaatta aacacatgaa acttgcagta gttacagata gttcggcata
    18901 tctgccggaa cgtatcaaga accatcccga cttattcgtt attccaatcc ctttgattat
    18961 ggatgggaaa atttataacg aaggaatcga tatcgaagcg gatgaatatt atggactttt
    19021 aaaaaacagt aaagattttc ctactacttc acaacctgtc gtaggggaag ttttgggttt
    19081 atatgaggaa ttgaaagaga aagggtatga cacgatttta agtatccatc tttcttcagg
    19141 gatttctggc tttgtcaaca cattatttgc gatgaaagat gacatcagcg gagtaacggt
    19201 cattccttat gactctaaga tcactagtat gccgatggga cacatggtag aagctgcctt
    19261 agacttaaat gatgaaggtc agtcccttga tgaaatactt gcacatatcg atcgaatccg
    19321 agataatacc tacgcttatc tgattgtaga tgatttgaac aatttagtac gaggaggacg
    19381 tttgacaaat ggtgcagcgc tgattggcag cttattaaaa atcaaaccga tcctgacatt
    19441 ttctgaaggg aaaattgttt tattcgaaaa aatccgttca agtaaaaaag catttgctcg
    19501 agctgaagaa attattggta gaagaaataa cgaaatacaa ccgccagtca aactttacgt
    19561 gatacatgca aataatttag aagtagcgat tgcggagaaa gagaaattgc agaaaaaata
    19621 tccaaatgca gaaatcgaaa ttggtcattt cggaccagtc attggtacac atttaggtga
    19681 aaaagccatc ggcattgcca tttcagcgca ataattcctt ttattcaaaa aacataccaa
    19741 aaatattcca acatcatctt ggactttcta catgttacta atgagcgtgt aaaagaacga
    19801 gatggtgttt ttatttctat caatgaagct ctttttcttt gcaatcctca cttcaatcct
    19861 ctataatgtc gcatatagtt tagtaaatga gtaaactact aatttactta tttactaaaa
    19921 ataaaaggat gaggagttaa aataatggaa ataccaacaa atttaaaaca taaaccagta
    19981 atcgttgtag aagactatga taaagttgat ggaagaaatg cattaaatac ggatgcaaaa
    20041 gggctttcac tgggccttgc tcagtggaat gatcgtggaa aagtcgatat ctcaggcaag
    20101 gtatggcgac atactggaga aaaatggtca cgacagtcgg aagaattacc aatcacacgt
    20161 attttagatt tagcgatctt agctgcacaa ggaagtttat acttccaaga tgcttatcgt
    20221 tatgaaaaat tttatgatcc agaaaatcca gtcgtagaca tcattggatt acaagggaac
    20281 cgaatgacgg tagaagtaga taccaaaaat ccaaagatcg atgaagacat cattttgtat
    20341 tacgatacac tacaaaaaga cggagaactg attggggaac gattccgtat tttaaaacgt
    20401 cttttagatg agctaggata ttaatagaca gagatgatca aaaggggaag agaagcatgg
    20461 agaatttctc actaacagaa aaccgaacct tttcacggct agaaaagcaa atgatctgga
    20521 agaaaccgaa aagccatcgg acaagtgcag aagaatggcg gatcgcctcc gaaatcaaag
    20581 ggaattggca agatcctgaa atgaaaatca gtaacgtact tttggaagga gatgccgggt
    20641 cggggaagac acaattagcc aaagcactat ctgctgatct gcaacttccc tatacaaaag
    20701 tgacctgttt tgcagatatg gacaaatcag atgttttcgg agccttatta cctgtagtag
    20761 attctaataa ggaacaagac caagaattac tagaagctat ttaccaaaca gatacacttg
    20821 aagctgtact gacactgatc cagaaccatt acggcattga tcctttttct gctaaagaaa
    20881 aattagcaga gctagttcaa aggatcgaag ctgattatcc agatgcaatc cattacagct
    20941 attacccttc tgaaatcgtt cgagcgattg aaaaaggata tttattagag attcaagagc
    21001 cgactgtcat ccgagatgcc tctgttcttg tggcacttaa ctcagcgctc gaaccaaatg
    21061 ggatgttgaa tttaccgaca ggaatcattc gtcgccatcc agattgcgtc attgtgatca
    21121 ctacaaatcg aaattaccaa ggaaatcgcc cattaaatga atctttaaga gatcggatgc
    21181 aacatgcgga aaaaatggat cttcctgcct tagaagtcat ggcagaacgt gcgatggcga
    21241 aaactatgat ccaaaaacaa gaacttctct taaagatggc agagattatc cgtttgttgg
    21301 atgaaactgc aaaagctaac gccatcaaag gtgtagcagg aatgcgttct tatttttatt
    21361 gggcaaatac ctataagcaa ggacaagatt tactccagtc gatttatcca aaagttttgt
    21421 ataaattatc cactgattca gatgaattgg caattcttga acaagctttg tctgacagtg
    21481 gattgctact ggaacttcag gacatattga gaaaagaaaa atggggtcat cctcaatctg
    21541 agcatacaaa aggaagaacc attagcgccg aagaagcaaa tgaacgaaac atcactgaaa
    21601 atgctgaaga aattctgcgc ttagatgaaa agaaatcgtt gtctgctgaa gaaccaaatg
    21661 agggagaaga gaaacaagaa gaaacaatag aaaaaaacga gattcctcct caaatgcaaa
    21721 aagaacgcag tagcgatatc gaaggaaaaa atcaaaaaga acaacaaaca ggagatgatt
    21781 ctcaagaaat gtctgcttct gacatggaag cacatgataa ggaaatcaag aagcaactga
    21841 ataaagaagc gcgacaaatc atgaaggaaa cgattcatga aaaagaaggt ctcatcgttc
    21901 accgaccagc tttccaagga aaaacgccgg aagcacgtga gctacacatg caagtaatgc
    21961 caatagtaga atcacttagc cggcaaattt tagagttact ggataatgaa caaacagaga
    22021 cgtaccaaaa aggaaaatac gaaggtcagc ggttcaatgc aagcaaagta gcatatggtg
    22081 atttgagaaa ttttgacaaa aagaacccgc cacatgagca accttcttta gcggtagctg
    22141 tacggatcga tgaatctggg tcaatgatac gggatgatcg gatcgaagcg gcaaaaaaag
    22201 cagcgattgc cattgccgaa ttttctaaga aagtcgatat cccattgttg atttacggag
    22261 atacagcaga ccgttcgtca agagaaaaga cttctttgtt ttcttataaa gaatttgaag
    22321 acggatttca atggttaaat gaaaaattag tcactatgaa accaaggcaa aacaatcgtg
    22381 atggtgctgc acttcgttta gcagcagaaa aattaaacag acaatccgca acaaccaaac
    22441 tgttgcttaa tattagtgac ggtcagccaa aagcgttgcc ggattataca ggcaaaaaag
    22501 caaaagaaga tatccagtct gttttgaaag aatatgaacg tcaaggaatc ctatttgtct
    22561 ccgcagctat tggccaagac aaagaagaaa tcaagtcgat ctacggtgaa agtcgttttg
    22621 tagatattac tgacttgaat gaatttccca agcaaatgat tcaactgatt gcccgctatc
    22681 tatgataaaa taaagctcaa cgaacgcact tagcagattc gttgagcttt tcgtttctag
    22741 ttaccggtaa caaggatact tctaaaatag aatcggttat aatcaagagg gaccgttaaa
    22801 ggagtgaaac gatatgatac aagaacaaaa atggtggaaa gaagcagtag gctatcaaat
    22861 ctatcctgct agtttcaaag atagcaatgg cgatggtcaa ggagacatca atgggatccg
    22921 tgaaaaactt aattatttga aagatcttgg tatcggcttt atctggatca atccgatcta
    22981 tcaatctcca tttgtcgata atggttatga cgtaagtgac tatcaagata tagaagagag
    23041 attcggaacg atggaagatt ttgatttatt gctaaaagaa gcacatgaat tagggatcaa
    23101 agtgattatg gatcttgtca tcaaccatag ttcggatcag catcaatggt ttgaagaatc
    23161 gaaaaaatct aaagaaagcc cgtatcgcga ttattacatt tgggtcgacg gggtagatgg
    23221 caaagaaccg aataattgga catcgatttt cggcggttct gcttgggagt attctcatga
    23281 aactggacag tattatctgc atgtttttgc aaaagaacaa ccagacttaa attgggaaag
    23341 cgagaaattg aaagaagaac tattcaatat gatccgatgg tggttggata aagggataga
    23401 tggatttcgt ttagatgcga tttctcatgt aaaaaaagat gaatattcag taaaagccac
    23461 agagaaccct ttctcaccct ttcaaaatgt ctcaggaatc gaagaacatt tgaccgattt
    23521 gaaacatgtt tttgaagagt acgatatcat gactgtcgga gaagcaagtg gtgtcactgc
    23581 agaagaagga ccacaatggg tagggaaaga cggttatttc gatatgatat tcgaatttga
    23641 tcatatccat atctggcagc aagaaaaaga agggcaatta gatgtcctta aattgaaact
    23701 tgcattaagc gcttggcaaa cttcattgga tggtatcgga tggaacgctt tatatatgga
    23761 aaaccatgat gttcctcgtg ccgtttcagt gtttggagat actcgtcccg atttttgggc
    23821 tatgtctgca aaagcaatcg ctatgatgta tttctttttg caaggtacgc catttattta
    23881 tcaaggacag gaaatcggaa tgacgaatat gccctttgaa tcgatcgatc aagttgatgc
    23941 agtagattcg aaaagacttt ataaaaggct gcttgcggaa ggtaagacaa gagaagaagc
    24001 attggatatc attcgtgaaa caacgagaga caacagcagg acacccatgc aatggacttc
    24061 ggaacaatat gctggttttt ctacacatga accttggctg atcactaatc caaataccaa
    24121 aacgatcaat gtagaacaac aagaatatga accagagtcg gtcctgcaat tctataagaa
    24181 catgatccgc attagacaaa ccaataaagg tctgatatac ggttcttata aagaatatct
    24241 tcatgaacat ccacaacttt atgtctatga aagatattta gaagatgaac aatatcttat
    24301 tatggtaaac ttaacagaat cacttgctga ctatgaactt ccaaaagaag cagatcagtc
    24361 ctggacatta ctcttgtcaa attcctctag cggagaattt gaagctaaag gcatactagc
    24421 accttatgaa gctcggttat ataaaataaa caagtaaaac ttcctcgtta aagttcatta
    24481 gttggacttt gcgaggaagt ttttcagatt gctctgtcaa ttactcattt caataattcg
    24541 ctctaggacc accgatatat ttaggacgag agcgaagggc tgtcacgtga gcttgtccaa
    24601 gggttttcaa acgaggtctg acaggtactt ggacatgttt gatatgcata ccgattgatg
    24661 tgtcaccgat atcgataccg gcttgtccaa ctacgtgttc cacttcgaca ggatcattga
    24721 actggtcaaa agcagcaaca gaacaagcac ctccagcatg tagtgcagga acaacagaga
    24781 caatttcgaa attttttgct tctgccactg ttcgttctac tactaatgct cggttcaaat
    24841 gttcacaacc ttggacagct agcgcaattt ctttaggatc caacaactct tttaacgtac
    24901 ggatgatcca ttgaccaact tccgcactgg aattttttcc aatatgtcct ccaacgactt
    24961 cgcttgtgct gcatcctaaa acaaaaagat cacctttttt caagtgtgcc tcagccaata
    25021 tgtcattaac tatttcagtc aattggtctt ttaattcttt ttctgacaac ttcattttct
    25081 aaaaccttct ttttcaatta atattgcttc cgtgcttgaa tacgttgaag acttgcagtt
    25141 ataggaaagg caagtcccat tccaatcaga ttttggaaga tgtttcctgg tatagaagcc
    25201 actccagccg gccaatcata taaaatccaa ccggcgatac catagccgat gatcataact
    25261 aagcttccta ataaaagccc taatccccac atacgagtag aagatttgct gaaagaacca
    25321 gcaacatatc cttgtaaccc gtggatcact aatgaaaaaa ctgcccactg cggatatcct
    25381 gaaatcaaat cgatcaatag accactggaa gcaccaacaa ctaatccacc cgttggacca
    25441 taaagaaaag cagcggtata gatcccggcc tcgcataatg tcacaaatcc attcgtagcc
    25501 ggtacaggga tcaaaattgt taatgaaagg gcaactgtca acgcaatcag catagcatag
    25561 atcgttaatt gcttagtttt catttctcat tcctcctttt tgaataccgc cagaccagac
    25621 acttccggta tgatcgttca tcagcacgcc attagaaata caatgggcaa caaatttttt
    25681 actttctgct actgctttgg taaaatctgc ccctaacaca agattcgctg ttattgcaga
    25741 agaaaaggca caaccggccc cgtttactgt tgtagtgtcg atttttttat gagaaaatac
    25801 ctcataatga tcaattgaat agagaagatc cacagcttca tctccagcca tccttgtgcc
    25861 gcctttgatc acaatgtttt ttgttcctga agcagtgagt tctttagcga gatggatcat
    25921 ttctgttaac gaagagggaa gagcttgacc agaaagtaaa gcagcttctg ccaaattagg
    25981 cgtaatcatc gtaacaagtg gaaaaagttc ttcgatgagc tgcgaaatat acaattgatt
    26041 gatcacagct tcagtttctt tgaatgccaa aacagggtct aaaatgattg ggatattttg
    26101 ttttgttttt atgaagtctc gaacaaccat gattgcttca cttgaattca ataacccaat
    26161 tttgatacca tctaatgaag tcattttatc aatcgaaact aactgtcgtt taagcaattc
    26221 caaagatata gattccagca taaatcgctc attaatatct agtgccccta tagaagtcaa
    26281 ggcgcttagt ccgaatagac caaaattctc aaaagttttt aaatctgttt ggattcctcc
    26341 accagcaaat ggatcagaac cgccaattgt caagattctt ttcataacat tttcctccat
    26401 gaataagagt ataacgaaat tttcaaaaaa gaaaaacagc caattggcat atttttatct
    26461 catccaattt aaaaaaacaa aaagaaaaga aagaccaaaa tggatctttc tttccttaaa
    26521 tagttaggac ttttgtgatt ttaattcttt ctcgatttga agccgttgca ctttcattgt
    26581 agctgttcgc gggattgcat caaaatcacg gatgataggg acgttcaagc gaggaagttc
    26641 atggacttgc tcccaccatc gattccaatc catttcttta tcaggagcta aagcaataat
    26701 cggttgtgga gaatgatttt tatcccttac aatcactact tctgccaaaa aatctaacga
    26761 atctaataaa aagtcttcaa tagctaatgt actattgatc gtttcgatca aatccacttg
    26821 ccgatctttc aaaaataggt ggccatgctt atccataaaa ccgtaatctc cgctatccca
    26881 ccaatcgcca taaacatttt cctggaaccg tgcatcttcc ttgtaataag tcaaagcccg
    26941 tcctttagac agtaattgta tatgaccatc tgtgttttca ggtaggacat tcccaactga
    27001 atctgtaatc cgagcgcttg tcatgtcttc cagtccaacg cccatatctc ttgcatcact
    27061 tgttttcaaa ctctctagtg tatgagcctt aagaatcatt ggtccgcatt cactttggcc
    27121 atatacttga agaaataccg catcctgtgc catcgacgtt cgcaaaaatg tcttcattgt
    27181 ctggttgttt atagcatcaa aagtggagtg atagtatcgg atacccgaaa aagcttctgg
    27241 atgctcctta gcagtaaaac gccactgaac aaagttattc ggatgggtct ctagtgcaat
    27301 tggccggtga gcttccaaca tatgaacaac ttttgaactt tgtgcgtttg ctaaaggcat
    27361 cataggaaat cccatggaca tcaaagaaga gataccaata ttgaatctgg aatgcactgg
    27421 agagatgtga aaagcgatta atttcttttc cgaaattttt gtgaaaactg ttttttgcca
    27481 tttcgtccgc catcccatag aatgagcaga atgacaaata agtttaggga taccagttgt
    27541 accagaagta tgggtcatat aagaaatttc atttttgtct aaaaatgatt gagaaacaga
    27601 caaagcaggt tgttccatta aataaagaat agga
//
LOCUS       DARPZF010000031        27310 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.032, whole genome shotgun sequence.
ACCESSION   DARPZF010000031 DARPZF010000000
VERSION     DARPZF010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.032"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            647..964
                     /locus_tag="SLE65_001731"
     CDS             647..964
                     /locus_tag="SLE65_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HEI8449025.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1055..1420)
                     /locus_tag="SLE65_001732"
     CDS             complement(1055..1420)
                     /locus_tag="SLE65_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449026.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1627..2109
                     /locus_tag="SLE65_001733"
     CDS             1627..2109
                     /locus_tag="SLE65_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449027.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2306..3196
                     /locus_tag="SLE65_001734"
     CDS             2306..3196
                     /locus_tag="SLE65_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEI8449028.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            complement(3483..4757)
                     /locus_tag="SLE65_001735"
     CDS             complement(3483..4757)
                     /locus_tag="SLE65_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEI8449029.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMNSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            5030..7501
                     /locus_tag="SLE65_001736"
     CDS             5030..7501
                     /locus_tag="SLE65_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEI8449030.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(7604..9340)
                     /locus_tag="SLE65_001737"
     CDS             complement(7604..9340)
                     /locus_tag="SLE65_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEI8449031.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(9337..10041)
                     /locus_tag="SLE65_001738"
     CDS             complement(9337..10041)
                     /locus_tag="SLE65_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8449032.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            10172..10675
                     /locus_tag="SLE65_001739"
     CDS             10172..10675
                     /locus_tag="SLE65_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HEI8449033.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            10635..10973
                     /locus_tag="SLE65_001740"
     CDS             10635..10973
                     /locus_tag="SLE65_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEI8449034.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            10994..12412
                     /gene="ffh"
                     /locus_tag="SLE65_001741"
     CDS             10994..12412
                     /gene="ffh"
                     /locus_tag="SLE65_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEI8449035.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            12524..13102
                     /locus_tag="SLE65_001742"
     CDS             12524..13102
                     /locus_tag="SLE65_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEI8449036.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            13106..13627
                     /locus_tag="SLE65_001743"
     CDS             13106..13627
                     /locus_tag="SLE65_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEI8449037.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(13706..14260)
                     /locus_tag="SLE65_001744"
     CDS             complement(13706..14260)
                     /locus_tag="SLE65_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEI8449038.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            14513..14788
                     /gene="rpsP"
                     /locus_tag="SLE65_001745"
     CDS             14513..14788
                     /gene="rpsP"
                     /locus_tag="SLE65_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEI8449039.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            14800..15051
                     /locus_tag="SLE65_001746"
     CDS             14800..15051
                     /locus_tag="SLE65_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEI8449040.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            15176..15967
                     /locus_tag="SLE65_001747"
     CDS             15176..15967
                     /locus_tag="SLE65_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449041.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            16137..16658
                     /gene="rimM"
                     /locus_tag="SLE65_001748"
     CDS             16137..16658
                     /gene="rimM"
                     /locus_tag="SLE65_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEI8449042.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            16648..17409
                     /gene="trmD"
                     /locus_tag="SLE65_001749"
     CDS             16648..17409
                     /gene="trmD"
                     /locus_tag="SLE65_001749"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEI8449043.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            17545..17892
                     /gene="rplS"
                     /locus_tag="SLE65_001750"
     CDS             17545..17892
                     /gene="rplS"
                     /locus_tag="SLE65_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEI8449044.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            18265..18927
                     /locus_tag="SLE65_001751"
     CDS             18265..18927
                     /locus_tag="SLE65_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449045.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            19006..22233
                     /gene="fss3"
                     /locus_tag="SLE65_001752"
     CDS             19006..22233
                     /gene="fss3"
                     /locus_tag="SLE65_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HEI8449046.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            22347..22661
                     /locus_tag="SLE65_001753"
     CDS             22347..22661
                     /locus_tag="SLE65_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEI8449047.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            22674..23048
                     /locus_tag="SLE65_001754"
     CDS             22674..23048
                     /locus_tag="SLE65_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEI8449048.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            23058..23402
                     /locus_tag="SLE65_001755"
     CDS             23058..23402
                     /locus_tag="SLE65_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEI8449049.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            23473..24618
                     /locus_tag="SLE65_001756"
     CDS             23473..24618
                     /locus_tag="SLE65_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEI8449050.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQCATCF"
     gene            25333..27192
                     /gene="ltrA"
                     /locus_tag="SLE65_001757"
     CDS             25333..27192
                     /gene="ltrA"
                     /locus_tag="SLE65_001757"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEI8449051.1"
                     /translation="MNKVKTNKTLRHSEYYGMTQIFDELYVKSDKKEVFTELMTIIMS
                     DENIRLAYRNIKNNKGSYTASTDKKSIRDIKTLSEDTFLTEVKVLFRCYKPRAVRRVE
                     IPKPNGKTRPLGIPSIWDRLIQQCILQVLEPICEAKFHNYSYGFRPNRSTHHAIATCN
                     RLANRGKLHFVVDVDIKGFFDNVNHSKLLRQMWTIGIRDKWLLGIIRSMLNAPIVLPT
                     GKVEHPKKGVPQGGVLSPLLSNIILNELDWWVASQWQNTTIETEKIMDRRDKGKGIDK
                     TNQYRALRRTNLKEIYIVRYADDFKIFCRKRSHADKIFHATKMWLKERLSLEISEEKS
                     KIVNLKKGKSEYLGFELKLIKKGKKYVVESHMSKKSMTRVKIQLKKQLRKVARPKNHC
                     EQAKEIGLYNSMVIGIHQYYGIATCVNLDCSKIAYTLKPFINHKLPTKKHGKILNTFI
                     KSKYGKSKEMRWLNNVPIVPLNYVQFRLAVPLSEGTCKYTESGRSKIHSKLKLDLALL
                     LHMMRNSNYERSIEFVDNRISKYSAQKGKCAITGKFLEYEEIHCHHIVPVKQQGTDKY
                     SNLIIIHKNVHALVHAIEEKIIHKYLNVLNLTNEQIEKLNELRVKAGNSVLTV"
BASE COUNT         9287 a         4756 c         5580 g         7687 t
ORIGIN      
        1 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tacattatgc
       61 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      121 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      181 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      241 ccatatattt gaatttacta agaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttataatta ggatttagag taattaatta gatgtttatt ttataggact gatactatag
      361 attacaaata gtatcgtatt tcgcaatctt aaaattatct tcttactgtg aataagataa
      421 taaaatttgt atttgtcctt tttaggtaac ttattttaat ctatatacct ttctggatca
      481 acgaaagtat actttatata gtcataacgc cgatggtaac tatgcactgt aacgataatg
      541 ctgctaaaat atctttttac gaaaaacatc acaaggaaaa acttaactat ggtattatct
      601 aaacataatt ttttcggtat ttaatattta attaggaggt aatattttgc ttttttatag
      661 taattttatc ttaatagtag cgatattatt acttctgaat atatggattt ttgataggag
      721 tagaaattca agtataggtt ttagaactaa acgaagtttg tcttctaaaa aaaattgggt
      781 atactcacaa actatttttt atggaggaat tgttttaatt agtttacttt cttcaacact
      841 ttattctttg aatattatag atgtttccac ctcaaattca atatctatta ttggaatcat
      901 tattgctgca attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa
      961 atagaaaaac tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga
     1021 aagtagcttc tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag
     1081 ataaggctac cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa
     1141 gcaagatcag ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg
     1201 cgcaaaataa ataggaagtg acagtagata taatattggc aatgaataaa gatataatac
     1261 gcctgttcct ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc
     1321 cgcttacgga atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag
     1381 ataaaagcaa cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa
     1441 gtgttattat tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc
     1501 attatttcta gattaaatga ataaactctc atgccattat ctctaaaaaa atgtttttcc
     1561 ccctaatttt tttagataga aaattgtata gtatgatgag agaaaaagta gtttggggga
     1621 acgttaatga gaagaaaagc agtaatcgat cggctttatt tatttttttg gttttttcct
     1681 atcgttttgc taccttttac atgggtaaat gctgttgtac aaggtgcgga gatattaggc
     1741 ctgatccaag gaagcggatt tgtggtttct aggaattttc cagctttgat tgttttctat
     1801 ttagtgataa gtgtaggtct cttattacca aaatctctga tcaatcacta caattggcag
     1861 ctgctttact tttcttgctt attagtattt acatctatgt tttctttgct gcctcgcttg
     1921 attatcggcc ctaatggttt gagcgagagt ggattgaagg atttagctta ttcctccatg
     1981 tatttcttga cgatcaaacc atggttctat ttagtaattg cctcatttat tcttgcaaca
     2041 tttttttact tctggacaga aatcaggata aaaagtgaac gatctgtatc tataaaaaat
     2101 aactattgat ggtggatcat cagtaaaaaa acatatgagc tgcgtaaaat gcatgtttct
     2161 catatgcttt ttttattatt atgtaaagaa tgcgaaaaac gtttacatga tttttacata
     2221 acttaactat atttttacag caaccatacg agggatttac agtcgactga taaactttag
     2281 ttgtaaataa gaaaggagca ataaaatgaa aaaagtattg tttactctag gtatgatggg
     2341 aattctttta gccggatgcg gctcaggatc aggaaataca gatggctctg ccacacaaaa
     2401 taattcaagt gactcaaatg aacaagtaaa aatcgttgcg gtaggttcga cagcattaca
     2461 gccgttagtc gatgcagcac aagaaagctt tgtacaagaa aatccaaatt atcaaatctc
     2521 tgtacaagga ggaggaagcg gaactggttt gagccaagtc gaagctggag cagttactat
     2581 cggaaactct gatgtatttg cagaagaaag agacggagtt gatgcttcaa aattagtgga
     2641 tcataaagta gcagtggtcg ggatggcacc aatcgtcaat aaagatacag atgtcaaaga
     2701 tatcaccaaa caggaattga ttgatatctt tacaggaaaa atcactaact ggaaggaagt
     2761 tggcgggaaa gatcaaaaaa tcaacgtcgt gaaccgtgca aacggcagcg gtacccgcgc
     2821 gacattcgaa aaatggggac tggatggtgc tacccctgtg cagtcccaag aacaagattc
     2881 atcaggaaca gttcggcagc tggtaagtca aacaccagga gcaatcagct atttagcttt
     2941 ctcatatctc gatgattcca cacaagcact aagtatcgac ggtgtagaac caaaagaaga
     3001 gaatgtagca gataacagct ggggaatctg gtcatatgaa catatgtaca cgaacggaaa
     3061 accttcccct gaagtccaaa aattcttaga ctacatgatg acagaagaaa tccaagaagg
     3121 acctgtcaaa gaattgggct atttaccaat cacaatgatg gaagtagaac gtgatcacga
     3181 aggaaatatc aaataactag cagataaaca tgccacggta gtcgttacta ttaaggaaaa
     3241 atcaactatg tttccccaca tatacatttt tcctttaatt gtgaaaaata gttcctcata
     3301 ttttgccgtt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tattcgaaaa
     3361 aaagagctac gacatagaac tgtcgtaact ttttttggct cttcgtcaaa tcgtgttggt
     3421 gaagacaaat ttgaataaaa cttagtccga tatgcggcgc gttctgtgcg ccgcatattt
     3481 ttttagtttt caaagatcag accttgttgt aaatagatcc gtgcccgaaa gttataaaag
     3541 ttgcgataac caaacgcaat tcgtttaatc agcttgatct tgttattcag cccctcagtg
     3601 acgccgtttg agtgggacac cttaaaggca tttgaaatac ccgattggta gcaatggaag
     3661 atcgtgaatt tctttttaaa cgactgaggt aacgtagatg aaattgtttt aagggtttct
     3721 tgaaagcctt ccgtacctcg tttaacgaaa taatagcgta ataattgaca aaaatgatac
     3781 gcagttcgca attcttcgtt gtagcttaac agctcatcaa cgatttctgt ttgactaatt
     3841 ggtcgtttaa acagtcgatg ataatgccgt ttgagtggct cccatgtcgt ggaatctttg
     3901 agtaagagtt tccaatatcg cttgagccga cggtacttct tctgattttc agagtgtgag
     3961 gttcgaaaac gattcatgat ctggacacgt aattgattga agctgcgatt gatgtgttgg
     4021 acaatatgaa agcggtcagt tacgatctcc gcatttggaa agactgtttt aagcaactga
     4081 caatagctgg cattcatgtc catcactagg tacttgacct ttaaacgggc ctttctagga
     4141 aagcgcagga agtattgagt tagtttgtaa agtctgcgat cttcaaggat cgtaaatagc
     4201 tgattggttg tcccatcaac acaaataaaa ctcatggaac cagaaacaga attcattgat
     4261 ttgaactcat ccatacacaa caccgtcgga aggaagttca tacgtggctg gtaatgcttc
     4321 gttgcttcac gcaagatccg tgtcaccgtc ccatccgaga cgaagtactt cttagcgatt
     4381 agtttacgtg attgattttc gtacagttcc atgagaatcg cctgcttcag ttcctttgtt
     4441 agttgatgat gttcatcaac taagtccgtt ttcgcagaaa aggtccttcc acaatcatgg
     4501 cagagaaaac gggtacgttt taattctaaa atagttaact tttctttgac tttcaacatc
     4561 tgagtgcgtg tcgtatagga accgttgcgg ataatacgaa ccgatcgaca gtgttcacaa
     4621 taggaagaag agtcatccaa ttttccttta ataaactgcg cttgaacgcc tttatattct
     4681 ttttcaatca gccattcttc atcaaaaaat aaatgtttat ctgttaatcc gagtaatttt
     4741 ctagtatgat tatccattga gagactcctt tggtaggatg acgttttggt cgactaaatt
     4801 ttaccaaaag tgagtctctt tttgagttga aacgaagaaa aagtgttagt agaaaatcgc
     4861 cttcgatttt ccaccaacac aaaatattat agaacccttt ttttttgcta tatgacagga
     4921 atgaaaggtg tttgcaagct taatgtgagg aacactttcc atatctgttc tatactggat
     4981 aggagaagtt tggaaatatc cagaaaacga aatcaatcga ggtagccaca tgaagaataa
     5041 atggataaat cgaagtaaaa aaaagaaagt aacacaaaga tcatcagata aagtcatccg
     5101 tctttttcca tcgtataaag aaggattaac ggcagatcaa gtcaaggaac gaatagaaaa
     5161 aggtgcagca aataattcag tcgatcccac attcaaaaca aatcagcaaa tcgtattgga
     5221 aaacatattt acgtatttca atttgatctt tcttatctta gccattttgc tttgtttagt
     5281 agaatcctat aagaacttga cttttttacc agttatcata gccaatacag gaatcgccat
     5341 ttttcaggaa attcgatcca aaaagatctt ggacgaacta aatgttttaa atacagcaaa
     5401 agtcaatgtc atacgagacg ggatagaaca aacaatagat atagaagacc ttgtaataga
     5461 tgacattgtt attttagaga ctggatatca aattccagca gatgcagagg tcgtggaagg
     5521 gaaactgcaa gttaatgagg ctttattgac aggcgaagca gatgaaataa ccaaagaaat
     5581 aggtgatcca ttaatgtccg gcagtttcat tgtttccgga aaagcttacg cccgattaga
     5641 caaagttgga gcagattcgt atatttccca gctgacagtc aaagccaaga caatgggaga
     5701 aggagaacag tcggagatga ttgcttctct taatcaattg atcaaatgga ttgggatcat
     5761 cattattcct atcggtatcc tgcttttttc tcaaagttac ttttttaatg gaaacacgat
     5821 caaagaaagt gtcgttgcaa tggaagcagc attgatcggt atgatacctg aaggactgta
     5881 cttgctgacg acgattgcat tagcattaag tgcgactaaa ctagcaaagc aaagagttct
     5941 tttacacaat atgaaaagca ttgagacatt ggcaagggta aatgtccttt gtgtagataa
     6001 aacaggaacg atcacagaaa ataaaatgtc tgttcaaaaa atgatcgtct ctaaaaaaca
     6061 agaaataatc agtcagtcag atcaattgga agcatgcatt gctgactatg caaaagcgat
     6121 ggcaggagac aatgcaacaa tggaagctgt taaagcatat tttacaaaaa ccactgatca
     6181 atcctatcac catgttattc ctttttcttc tgtccaaaaa ttcagcagtg tagcgttggc
     6241 agacaaggtg tatgttttag gagcgcccga aatggttttg cgcgatcaat tgccggaata
     6301 tgcggaagag tttgtttctt tcgctgaaaa aggctatcgc gtgttggtct ttggtgtgta
     6361 cgatgggatt cttgaagaac cagtattgac agaagcagtc acaccattag gctatattct
     6421 gattgctaat cctatcagaa aagaagcaag agccacattt gattacttca aaaaacagca
     6481 agtagccatc aaagtgattt ctggagataa tccgctcacc gtatccaatg tagctgtcca
     6541 agcagggatt tcacatgctg atcagtacgt tgatgcatct aaattatcag aagaagaata
     6601 tgaagcagct gtcgaaaaat atacagtttt tggacgcgtc aagccagaac aaaagaaaat
     6661 cttcgttcaa ttgataaagc gtaacaatac agtagctatg acaggtgatg gcgtgaatga
     6721 tattctagcc atgaaagaag cagactgcag tatagcgatg gcttccggaa atgaagccgc
     6781 catgcaggcc tcacaagtgg tcttacttga ttctgacttt tcacgcatgc cagaagttgt
     6841 tgcagaagga cggcgcgttg tgaacaatat tgagcgatca gccagcttgt ttttagtgaa
     6901 gaatattttc tcctttttgc tctcactgtt ttcagtgatc tttgctctga cctatccttt
     6961 agaaccatca caaatcacat tgattagttt gtttactatc ggacttccat ctttcttgct
     7021 tgctctagaa gaaaacaaaa agcgaatcag agggaaattc atcatgaatg tgatggaaaa
     7081 agctgtgcca ggtggactaa cagatatgat cgtagtcggt gcgttggtga tctgcggggt
     7141 gactttgaat ctaaataaaa cagatgtttc tacagcatct accatgcttt tgattgcagt
     7201 agggttcctc gttctctata aaatctgttc accgctgaat aaattcagaa gtcagatcat
     7261 tcttttctgt gctagcggta actttttttc ggtcatcttt ttgcataagc tgttttcaat
     7321 caccggtatc tcagctgtat cacttttgct gttgagcatt ctatttttct cggcagattc
     7381 gatttttagg catttgacca cattggtaga atatttgttt gaacgtaaaa atgaaaaaga
     7441 gcaaaagccg tttagtcgcg tagctaaaaa atttctatcg atatttaaac gagaaaattg
     7501 acgaaaagta tctcaaaaaa gagtaaaaaa gaacaaccac tcgtgtatct ttcgaagcag
     7561 gatgagtcat ccaactttaa aacgcacgag cagttgctct tttttacatt ttcggaatgg
     7621 taacggtgaa agtcgaacct gttccaagat gactgtctac agtaatcgta ccattaagga
     7681 gttgcacgta gtcttttaca atcgctaacc ctaatccggt cccgcctgaa tgtcggcttc
     7741 gcgccttgtc tacgcggtaa aaacgctcaa agatccgttc ctgatcctca atgtcgatac
     7801 ctataccaaa gtcttggaca gaaaacgata gatcatctgt tgcctgatag cggataataa
     7861 tctcgctgtc gctttttgaa tattggacag cattttcaat cagatttttg ataattggat
     7921 aaaggatatc tgttttagta gtaaatggtt cgttctttcc aatcaatcga atcgtcaacc
     7981 gtttcttttc gatgattggc tgataatttt gaacgatttg ctggaaataa ggttctgtat
     8041 aaattgtctg gatctcgtaa gaattctcgc catcttttga cagctggatg atttcccgaa
     8101 tcagtttatc taaccggatc gcatcttttt gcatgatctc aagaaaagaa gtcagagttt
     8161 gcgggtcatc ttttgcacca tccagtaaag tctcggtaaa accaatcagt gaagtcacag
     8221 gagtttttaa ttcgtgagag acgttgccaa cgaaatcctt ttgtagcttt tctaaacgtc
     8281 gcactttcgt taagtcatac gccaccccta gaatctgtcc ggtaccttct gaattagtaa
     8341 agtagcgcaa actcaagtct aatgtctgcc gaccttctgt aagggtgatc tcctgatgga
     8401 tcagcggatg ctcaggagtc acttgatgaa tcagctgaat gagttttggc tcttgaatga
     8461 cttctgtgta ccgctgttca ggttgatagc ttaccacgtt taaatgtagc tgcatctttg
     8521 gattaagcag tagtaaacga gaatcagcat catcaatcag gaatacgcca atcatcagtt
     8581 cgttcagtaa cgtatataat tgctcttctg tggtagtaca cgcccgatac atcttactca
     8641 tttgttcgct caacgcatta atcgtctgat acaattcttc ccattgatcg ggtgtttgca
     8701 tgattacttc cgcctgatta ggattttgca ccattttttt tagtacgggc agcacggttt
     8761 tcaatggctg gtttttttga tagatcagat aatagatcat tcctgcaaga acaaggaaga
     8821 aagacagaaa gaagaaaaag acccaacggc gaaaactctc agttctcggt aaaaaaacgc
     8881 ttgtcggttc tgcgatacgt aaaatggctt ctaactggcc actttttttg actggtaatg
     8941 cgacatataa aagatcctca ttcaaagtag tacttttgcg caaagcgcta cctaggttcc
     9001 caccattcaa tacggctttg atttcgggac gggagtttcg ctgttcattc aatgtttcat
     9061 tgtttgtgtc aaataagatc tttccagtag catccattaa agtaatccgt tcgttcgact
     9121 gatggacgaa ttcttccaaa gcagttttgt tttgcgctgc ttggaggttt tcgacatcta
     9181 attgccggat cagcagttgt gctttttttg tcaggtagct ttcttgctgt tccacgatct
     9241 gctgttgaaa ataatgggaa atcaattgcc agccaccaaa aaacaaacta actaaaagaa
     9301 taagaaagaa gagacgttca taaatttttt tccatttcat cgtttgggtt cctgaaactt
     9361 atagccaaat cctctaatag tcaccaagta ctttgggtgt tttggatctc gctcgatttt
     9421 ttctcgcaaa tgactaacgt gtacatctac gattcggctt tgtcctgcga agtcaaaatt
     9481 ccaaatgcgg tctagcaatg tgtctcggtc gatcacacgg tcttttcgtt tcatgaaata
     9541 aacaagtaat tcaaattctt tcggtgttag ttcaatcaga tggtcgtcta cggtcacttg
     9601 ataattggtc aaatcagcag tgatttgtcc aatcgataga tattcaggct cagcttcatc
     9661 ttttgattgc ttacgaggtt caattcgtct gaatattgct ttcatacggg ctaatacttc
     9721 gcgaggacta aatggtttgg tcaaatagtc gtcagcacct atttctaggc caatgatccg
     9781 atccacttgg tcatctttag ccgtcagcat caaaatcggt gtttcatttt tttcttgacg
     9841 cagccgctga gtgatctcca tgccatccat cgttggaagc atcacatcta aaatgatgaa
     9901 atcaaatgat tgttctaatg ctaattctaa tccttcgcct ccatctgtgg cactggttac
     9961 cttgtagcct tctttttcca aattgaacgt caagagcgtt acaatagaag gttcatcatc
    10021 aacaactagt atttttttca ttcaaatctc ctttaaatag gtttcattct gtttatattt
    10081 tagcatagaa tcagtacaaa gggctatttt acaaaagaaa taaatggtat aataggaagg
    10141 cactttgctg aatagaaagg aagagcagtc aatgattgga atcagtgcat gtttaggcgg
    10201 tctggcctgt cgctatgatg gacagaaaaa agaagtacca gaattgatgg aactagttga
    10261 aactggagaa gctgtcatgg tctgtccaga agtgatcggc ggattaccaa ttcctagaga
    10321 tcccgctgaa atcattggtg gaaatggatt cgatgtgtgg aaagatcaag caaaagtatg
    10381 gacgacaagc ggcgaagatg taacggaagc gtacaaaaat ggcgcgatca aagcctatca
    10441 aaaattgcag gaaaaacaca ttgatctagt catcatgaag gaaaaaagcc cttcatgcgg
    10501 aacccattcg atttatgacg gaagtttttc cggaataaaa aaaaatggtg ccggagtggc
    10561 tactgcttat tttattcagc aaaaaatgac tgtgctctct gatgaagaat ggctgaaaac
    10621 tagaggtgag cagaatggaa atcgaaaaga ccaatcgaat gaacgcgctc tttgaatttt
    10681 attcgacctt attgacagaa aaacaaatga actacatgga attatattat gcagatgatt
    10741 tttcattagg tgagatcgcg gaagaatacg aagtaagccg acaagcagta tatgacaata
    10801 tcaagcggac aagcaagatc ttggaggatt atgaaaaaaa actccatctt ttttctaatt
    10861 atattgttcg agaacaggta ttggaaaata tgactgcata tattacagat aagtacccgg
    10921 aagataaaaa actacttgaa tatgtacagc aaattcaagc aatcgaagaa taaataaaag
    10981 gaatgaagaa aatatggcat ttgaaagctt aactgaacgt ctccagcagg cgatgggaaa
    11041 aataagaaaa aaaggaaaag tatcagaagc tgacgtaaaa gaaatgatgc gggaaatccg
    11101 ccttgcctta ctagaagccg atgttaactt gcaagtagtc aaagatttta ctaagcgcgt
    11161 acgcgaacgt gcggtagggg cagaagtgct ggaaagttta tcacctgcac aacaaatcgt
    11221 aaaaatcgtt gatgaagaat tgacgatcac acttggttct gaaacagcag agttaaataa
    11281 atcaccaaaa ataccaactg ttatcatgat ggctggtctt caaggggcag gtaaaacgac
    11341 ctttactggt aaattagcca attatttaaa gaaaaatgaa aatgctcgtc cgctcctaat
    11401 cgcaggggac gtatatcgac cagctgcgat cgaccaattg aaagtattag gtcaacagct
    11461 agacgttcct gtatttgata tgggaactga agtcagcccg gtagagatcg tccgtcaagg
    11521 gatggagtta gcaaaagaaa agaaaaacga ctatgtattg atcgatacgg caggacgtct
    11581 gcatatcgat gaaacattga tggatgagtt gaaacaaatc aaagaattga cgcaaccaaa
    11641 tgagattttg cttgttgtcg atgccatgac tggtcaagat gccgtcaacg tagctgatag
    11701 cttcaaccag caattaggta ttacaggggt cgtcatcact aaacttgatg gggatactcg
    11761 aggcggggca gcactatcga tccgctcagt gacaggcgca ccaatcaaat tcatcggttc
    11821 tggtgaaaaa ttgactgact tagaagtatt ccacccagat cgtatggcta gccgtatcct
    11881 tggtatgggg gatatgctga cattgattga aaaagcgcag caagactacg acgagaaaaa
    11941 agcggaagaa cttgcacaga aaatgcggga aaattcattc gatttcaatg actttattga
    12001 acagcttgat caagtgatgg gtatgggccc actggaagat ctaatcaaaa tgatcccagg
    12061 aatgaatcaa gtccctggaa tcgaaaacgt caaggtagat ccaaaagatg ttgaacgcaa
    12121 aaaagcgatg gtttattcta tgacgccagc agaaagagca aatcctgatc tgttgaaccc
    12181 aagccgtcgt cgccgaattg ctgccggttc tggaaacagt gttgttgaag tgaatcgaat
    12241 gatcaaacaa ttcaaggaat caagaaaaat gatgcagcaa atgtccaaag gggatatgaa
    12301 catcccaggt atggaccaaa tgtttggttc aggcgtcaaa ggaaaactag gcaaaatggc
    12361 gatgaatcga atgatcaaga aaaataagaa gaaaaagaaa aaacggaaat aagatgaaaa
    12421 aaacagcttc ggtacagact gaaaatgtct actgccggag cttttctatc agcaattttt
    12481 attctttact aatacaatta ctctaaacga agaggtggca cagatgagat gtccgtggag
    12541 tgaacaaaca gaaagtatgc ggcaatatca tgatactgtc tggggtgttc ctgaatatga
    12601 tgaccaaaag ctgttccgaa aattgatgct tgatattaat caagccggat tgagctggca
    12661 gacgatttta aataaaagtg aagcattcga tgaagcatat gatcgattcg atatcaaaaa
    12721 agtcgcaaat tatggagaaa caaaaatcag tgaactaatg gaaaacaaag gaattattcg
    12781 taaccgaaga aaaatcgaag cagccgtcca aaacgccaaa gcagtcttga aaattcaaga
    12841 agaaatcggc agtttttcag agtatctttg gtcgttttct aatggaaaaa tcgttgattc
    12901 ttcttatcat tcacaagaag aagtcccaac aacaagtcct ctttcagatg aattagcaaa
    12961 agatctaaag aaaagaggat ttaaatttat cggaagcaca acaatctatg cttttttaga
    13021 agctgtcggg atcatcaatg atcaccttga cagttgtttc cgcaaagaag aggtcgtacg
    13081 tatcggcaga aagggcgaat aaagcatgcg aaaaatcata ttttatggtg ctataagttt
    13141 agatggctat ttggcaacga aaacggatga tcttcaatgg ctttttgaca ctccaacagg
    13201 taagcaaact acttatgaag ctttttatga aacaatcgat acgaccatca tgggcagaaa
    13261 aacttatcag gaagcaaaaa aatatttgga gaccgaagca atttatccag agaaaaagaa
    13321 tttcgttttt tccacccacg cacaattaca attgccagat gctgaggtcg taaacgaaga
    13381 tcctgttgct tttctaaaaa atctacaaat gacagaagga aaagatatct gggttgtggg
    13441 tggcggtcga ttgatcaaac cgctattgga acatcaaatg attgatgaat ggtatatcca
    13501 gattacccct gtattattag gggacgggat tcctttattc caaaaaggaa catatgaagc
    13561 gcgttttgaa atgctagaca cgacacgatt cggtgaattt atcgaattgc attatgtacg
    13621 aaagtagaag taaataaaat aaaaaaggca actatatgca gaaatgtcct gtacatagtt
    13681 gcctttttta ttaccgttat gctttttact ctgttaattt gttagaaaaa tctagatacg
    13741 catctaaaat cgtttggaag aaacttaatg ttccttcaac gatattacca ttttcatcaa
    13801 ttagattcgc aacgtttccg atatatgctt ccggttgctg caaggttggc acattcaaaa
    13861 agacaagtga ttggcgtaga tggtggtttg cgccaaagcc gccgatccca cctggtgatg
    13921 cagtaacgac taaacctggt ttatgatccc aaacactgtg tccataaggt cttgagccta
    13981 catctaaagc atttttcaat actgctggca cagaacggtt gtattcagga gtaacgaaaa
    14041 cgacaccgtc tagtcccctc acttcctcac gaaaacgagt ccattcagca ggagcctgtt
    14101 ctggagtttc gagatcctca ttgtaaaatg gcagatcatc gatttttaca aatacacttt
    14161 cgtacccttc aggaagcaat ttcgcaaaag cttctgctac ttttttgttg taagaatctt
    14221 ttcttaaact accaataaaa aatccaattt tttttgtcat acgatttttc ctccttcaaa
    14281 ctatctataa taatcttaca aaagataagt aactggagca aataaaaaca cttactgaca
    14341 aaagctacat agaagataga ttacttattt ttaacaaaaa agaagtctaa aatcttctat
    14401 tttctaaaaa aaatcgaatt taatcaagct gtaaagaaaa aaagctttac agggtaaaaa
    14461 aaaactgtta cactacatct tgtgaataaa acaatggagg tggaaataaa taatggcagt
    14521 taaaatccgt ttaaaacgta tgggttctaa aaagagtccg ttttaccgta tcgtcgtagc
    14581 tgattcacgt tctcctcgtg atggacgttt catcgaaact gtaggtactt acaatccttt
    14641 gaaagaccct gcagaagtag ttttaaaaga agacttagtt cttgactggt tatcaaaagg
    14701 tgcacaacct tctgacactg tacgtaacat cctttcaaaa gaaggcgtta tgcaaaaaca
    14761 ccacgaagct aaattctcaa agaaataagg tgaccggata tgaaagattt aagcgactta
    14821 gtcttaacaa tcgttcgtcc gctagtcact tatcctgatc aagtcaagtt agacgtcgta
    14881 gagtcgaaag acttttacga gtacaatcta acagtggctc ctgaagatat tggccgtatc
    14941 attggaaaac aagggcgtgt tgctaaagca atccgcacaa tcgtttacgg tgttcggatc
    15001 aatgcaccga aaaaagtgcg tttgaatatc atcgatgata aggaaaagta aataaacgtg
    15061 ctgtactcga attttcgagt gcagcttttt tgtttttttt attaattgaa gaaatgatta
    15121 tttggcaaaa caagcaagaa agcgtatcct tataggagga gggagtgaac agccaatgag
    15181 aaagaaaatg ttatttattc catttgctct attgttaagc gcttgtagtt cggttactca
    15241 agaatcagac aatacacatc tatcaagcag tatatctgaa actgttacca gtccagaaaa
    15301 aagtagtacc aaaacggctt ccaccactga acaaacaatg gctacctcaa ataatgagaa
    15361 aaagactgct ttagaccagt tgaaagaaca acagccaaat gttcccatgc ctctagatgt
    15421 accagtctct tcaggctatc tcaatatcgc agcgacacat acaaagcaag gttattctat
    15481 tttatattac agaacagatc gtcccctcgg gttgaatgct gacgaattga atcaagaaac
    15541 gcctattgca acctatctat atcaatatgg gtttgcttct agtcaagaaa caatccaagt
    15601 tttgcagcca tttgagatcg acacaaatgg tcagcaagtg gacttaggtt ctcgaatcac
    15661 agggtatcag caaggtgcag caggttcaag ttttcttgaa tggcaagaag gaaactggcg
    15721 tattcgaatc cgtgggaata atatagaagg ccaagatccc ttactattag ctaaagaaat
    15781 cgtagcttat ttggaagaaa acagtctacc agcacctgaa caatttggta aaattactgt
    15841 tgatatgggt gatacgacga atcgagccgt agaagtaagc tggcaagaac cgaaaaatgc
    15901 ctatacgatc actcatcaag atcctatgtc tgcgttgaag atggcagttt ctatgaagag
    15961 gttgtgaaat cagcgcgctg atctgagccc atcatttaac tccaagtcac aggaagtaat
    16021 caaaaatagc acgccgcatt tttgcataat tttggcttaa taccttaaaa gaaaactaga
    16081 attgcctctt cacacatgct aaaataaaac agacaaaaaa gaaatgggga tataagttga
    16141 ctgaatactt gaatgtagga aaaatcgtaa acacacaagg tatcaaaggc gaagtccgtg
    16201 ttatctcaac aacggatttc ccagaagaac gttacaaaaa aggaacggtg ctaacactat
    16261 tccaagacgg aaaagcacct gtggaattaa cagtcaaaag tcatcgcaaa cataaaaatt
    16321 ttgacttatt gagttttgaa ggacatcctt ctatcaatga tgtggaaaaa tatcgggatg
    16381 gcatattaaa agtgtcaaaa gacaactctg tagatctagc tgaaaatgaa ttctattacc
    16441 atgagatcat cggtctgcat gtattagaag atggaactga gttaggtaaa gtaaaagaaa
    16501 tcttgtcacc aggtgccaat gatgtttggg tcgttcaacg tccgaaaaaa gctgatatat
    16561 tgcttccata tatcgcttct gtcgtcaaag aagtcgattt agaagctgga gtggtccgtg
    16621 tagaaattcc agaaggactg attgacgatg aagattgatg tattgacttt atttccaaga
    16681 atgtttgaag gtcctatggg ggaatccatc atcggtaagg ctgtagataa aggattatta
    16741 gatatcaata tctctaactt ccgcgattat tcagataaca aacatcagac agtagatgat
    16801 tatccatacg gcggtggagc aggtatgctg ctcaaagtcc agcccatcta tgataacatc
    16861 caagccattg aaaaagctgc accggatgtc aaaaaaagag taattcttct tgacccagct
    16921 ggtaaacgat tcgatcagaa aatggcagaa gaattttcac aagaagaaca cttagtattc
    16981 atttgtggtc attatgaggg atatgatgaa cgtatccgca cattagtgac agatgaagtt
    17041 tccttaggag attatgtcct tactggggga gaattaggtg cgatggtcat gatcgatgca
    17101 acagttcggc ttttgccaga tgtgttaggg aatcagactt cagctcaaac ggattcttat
    17161 tcaaccggtt tattggaaca tccccaatat actcgcccgg cagaatataa agggatgaaa
    17221 gtaccagaag tattgacaaa tggaaatcat aaattgattg aagaatggca attaaaagaa
    17281 tcactaagaa ggacctatca acgtcggcct gatcttttgg aaacacttga atggacacct
    17341 caaatgacga aatttttaga agaaatcaag aaagaagaac aagaaaaaac agcagatgaa
    17401 gccaagtgac tttttctaaa atcttcttta cagtaggttg ataatatgtt agtattttat
    17461 ggtgagtgca aaagcactta actattacga tattccgctg tgagaaaagc tcataagaat
    17521 atttggaata aggagaagaa aaccatgaat ccattaatcg aagaattaac aaaagaacaa
    17581 ttacgttctg acatcccagc gttccgccct ggtgacactg tgcgtgttca cgcaaaagtt
    17641 gttgaaggta ctcgtgaacg tatccagtta tttgaaggtg ttgttatcaa acgccgcggt
    17701 gctggaatca gcgaaactta tacagtacgt aaagtttcta acggagtggg cgttgaacgt
    17761 acattcccat tgcatacacc acgtgttgca aaaatcgaag tagttcgcta cggtaaagta
    17821 cgtcgtgcaa aattgtacta cctacgtgca ttacacggaa aagctgctcg tatcaaagaa
    17881 atcagaagat aaacacggaa aacttccttg gaaatctgaa atttgtgaaa agtccttgta
    17941 tatcaagggc tttttctttt ttctctatca cagttttaag ccatttttgg ctgttttgga
    18001 ccatttttca atcatattcc cttaaaaatt gtcctagatt gtccgacatt gactatcagt
    18061 gtcgtcaaaa tagggcaaaa tttagtagtc agcttgacga caaatataat acgaaaaata
    18121 ccaaaacatt taccgaattt agcaactttt gaacccaagt ttctcaaagg gtcagctatt
    18181 agcaaaaaag acaaaacatg tacttttcta ctaaaaagtt gatgtgatag gcttctatct
    18241 aaataactat taggagtttt tatcgtgaag caaaatgatg gacgtatcat ttggaaaaat
    18301 caaagtgagt taaaactgat tttaacaatt aatgaattca tcgaaaaaca cggaattaca
    18361 tctagccgtc aataccagaa aaagctatca gaaaatccaa attctgcacc aagtatgtgg
    18421 ttcattaaca aaaaatatgg atcatgggag aatttattga ttagtatagg acgagaaaat
    18481 actgggtatg gaaaatgggc tagaatgtca gaacaagaat tattggaaat agtagaagcc
    18541 tttattaagt gcgagaagat aacctctcaa cgaatgtacg aacaaaaatc agtagggaag
    18601 aatattcctt cacttagtac cattaaaaag atgttaggag atatacgtcc actttttaaa
    18661 gaaaaaaatg atggatctcg atttactgat ttcgaactgc tgttagaact aaaaaatgaa
    18721 ataatccgat taaaactaca ggatgattta tcaatgacaa agtttcgaaa actagttcaa
    18781 tccccaaaac taccatcagt tgatacaatt atgaaaagaa cgaacaaaaa ttgggaggaa
    18841 ttgatggcag agattggatt tgattatcga agaatcaaaa tttataagca gagaaacaac
    18901 ctatccaaga caaagaaaac taaatagtat cactctaaat cagacgttca aaattaaaat
    18961 ttggacgtct tttttattac ccaaaaacga aaggagattt attttatgaa aaagccaaga
    19021 tttaagaatt ggcgtttgct cgcaacactg agtctattat gccaaacaat tggtggatcg
    19081 cttggcccaa cgattgcctt tgctgatgaa attactcatc cacaaacggt aactgtggaa
    19141 ttggatttgg ctcaccagta tgctgtcgaa ggtacattta gcgatggtcg tcccatgtca
    19201 gaagttaccg ttccgcacta tgcagtttac aatggtgtga agcaagatat tttctgtatt
    19261 gagccagggg tgccgattta caatgagttc actcctggtt atgagaaaaa tccattgcct
    19321 gatatgtcgg agaaagcgaa attagtttcc gttttatgga aggaagctgg tacggatgtg
    19381 gatacacata ttgtggccca gaagatgatt tggcaagaag ttaatggcta cacgcttcac
    19441 tcaattaaac gttctgatgg tagtgcagta aatatcgcag ccattgagtc aaaaatcaat
    19501 caagccattg cggattatca aaagaaacca agcttccata actccacagt gaaaaccgtg
    19561 ttaggtcaat cgactactgt gacagatacg aacggcttga atttatcgga gtttgatgaa
    19621 gttgtcgaga atatcgcaaa tattgattat cgtgtgaacg gcaatcaact agtgattact
    19681 ccaaatgcca attcaaaaga gagtggtgaa ttaaccctaa agaagtcagc taatacagga
    19741 acaccggtag cttataaaat ggctggtcaa caaactttga tggcgggggc aattgataag
    19801 cccaatacct acacaatcaa aattgatgtg gaaactgagg gttctttgaa gattaaaaaa
    19861 gtcgataaag aaacaggaaa tgttgtaccg ggaaccgttt tccatttaga ctttggaaaa
    19921 acattacctg caaaagacgt gaccaccgat aaagaaggca ttgcgacatt ggatgagatt
    19981 cctcatggcg cgaaagtaac cattactgaa aaatcagtgc cagctcctta tacgattgac
    20041 actacaccaa tcaccgcaac cattaaatct ggtgagacta tttctgtgac ttcaaaaaat
    20101 actcgcgaaa aaggtcaaat cattttgaat aaaatggggg tggaaacagg aactgatctt
    20161 tggaacgaca aatactcatt agccggaaat acgtttgcca ttcgcaaaga cagtccaacc
    20221 ggtgaaattg tccaagaaat gaccacggat gaaaaaggtc atgcggaaac accaaaagag
    20281 attgccaatg cgttggaatt gggaacctat tatgtgaccg aaaccaaagc tagtaatggc
    20341 tttgtgaata cctttaaacc agtaaaagtc gaattgaact atgtcaatca aaccgtggct
    20401 cttgttacca gtaacgtaaa agggcaaaac caagaaatca ctggtgaaac cactttgaca
    20461 aaagaagaca aagataccgg taatgaaact caaggtaaag ctgagtttaa aggagctgaa
    20521 tatactctct ttactgcaaa agatggtcaa gcggtcaaat ggagtgaggc ttttaaacca
    20581 gagttagtga agggaacgaa agcttctgat gaaacggtga ctttgacttt agatgaaaag
    20641 aatcaagttg ctgttaaaca cttagcgatt aatgagtatt actggcaaga aaccaaagca
    20701 cctgaaggat ataccttgga tgaaacaaag taccctgttt ccatcaaaaa ggtggatgat
    20761 aacgaaaaaa atgccgtgat tacccgagat gttacggcaa aagaacaagt cattcgcttt
    20821 ggctttgatt tctttaaatt tgctggatca gctgctggga ctgccgaaac tggcttcaat
    20881 gatctgacct ttaaagtatc gccattggaa ggaaccagtg agattacagg tgccgaagat
    20941 gaagcaatta cagcttataa cgagcaacta ggttttgatg gctatggcaa gtttgaaaat
    21001 cttccttatg gggattattt acttgaagaa gtagaggctc cagaaggatt tcaaaaaatt
    21061 acgccattag aaatccgttc tacttttaaa gaaaataaag cggattacac taagagtgaa
    21121 tacattttta cgattaccga aaaaggacaa aaacaaccaa ttaaaacggt gaccgttcct
    21181 tacgagaaac tgacgaataa agcattttct gttagcttga atcgtttgat gctctatgat
    21241 ttacctgaag aagaagatag cttaacttct cttgggactt ggaaagacgg aggcaaagaa
    21301 ttgacagacc ttgattctac cgagctagtt gataaattga gctataactt gcatgaaatc
    21361 aaagaagact ggtatgtggt agcgcaagcc attgatgtgg aagcgacaaa agctgcccaa
    21421 gaaaaagatg aaaaagccaa accagtggta attgccgaaa caaccgcaac gttggcgaat
    21481 aaagagaaaa caggaacttg gaaaattttg cataaattaa ccgcagaaca agttttggat
    21541 aaaaccatcg tcttattcaa ctatgtgtat gaaaacaaga aaccctatga agcaggtgat
    21601 gatccagtag cgaaagatgc tagcttgaac aatcaagccc aaactgtcaa ttgtacggtg
    21661 gaacgccatg tttccatcca aacaaaagcc cacctagaag atggttcgca aacctttact
    21721 catggggatg tggtggatat gttcgatgat gtgtcgatta cccatgatgt actggatggc
    21781 tcaaaagaag cttttgaaac aattctgtat gcattacttc cggataatac gaccaaagaa
    21841 atttggaaat ctggcaaaat tgattatgaa gtgaatgaca aagaattcac taaaaccgta
    21901 cttgcggaaa aagtggacac aagtaaatat ccagaaggta caagttttac cttcaaagaa
    21961 attaactatg gcaaagacgg aaacatcaat gggaaacaca atgaggatct aaaagaaaaa
    22021 actcaaactt taacacctaa aaaagttccg acaacaccaa gtgcaccaga acaaccggaa
    22081 ataccaactg ttccaagtga ctctcaagaa tctagtccta cagtaaagac attcccacaa
    22141 acaggggaga aaaattctaa tgttctgctg tttattgggt ttaccttgat ctttgcgact
    22201 gctgggtatt atttctggaa tcgccgaaac taaggtgatg tgatgaaaca actaaatagg
    22261 aaaaaccaac gtgcgcgacc gcctcctaaa aaaagtggtc gcgctatttt tgtatccaaa
    22321 actaaaaatg aaaagaggaa aagaagatgg aattgaaatt tgttgtgcca gatatggccg
    22381 aaacctttgg aaagataagg tatgccggcg aaggcgaagt tttaactgaa ggatatgggc
    22441 ggaatactac agtaattggt cgtagttatc atttgtattc cagtaagcaa cgagccgatg
    22501 atattgaagt ggtggtagct gcggaagccg gcgaaaagga ttttgatcaa gatcaaccac
    22561 taaaagccgt gaatccccat ttggttgcca aaggctatga gattgagaat cgtgggttta
    22621 ccgactacgt gttgtatgtc gatgatttag tgaaagcata ggaggaaaag aagatgagat
    22681 taacagaagg tattgttgta gattcaggac taacgtttgg gaaattacga ttttccgcat
    22741 tacgccgaga agtacggaag caaaatgagg atggaacggt tagtaacgag gtaaaagaac
    22801 ggacttataa tttgaaatcc tctgcgcaag gtcgaatgat ccaagttagt atcccagcaa
    22861 atgtaccctt acgcgagttt gcctatgacg cagaggtaga gttggtcaat ccaatcatgg
    22921 atacggtcgc caattatgtt ttccgagaag gaactactgt caattggttc attaaggccg
    22981 atgatttagt cttgaaacga caaccagatc agggaaattc tacaaaccaa aatgaaggaa
    23041 agaaataggt gaagcgtatg gaaattaatg ttgaacatat tttagattgt ctcgatcaat
    23101 atggaaaagg tgagctaacg gaggaacaac tcactaaagc attaacctat gatgaaaaaa
    23161 tgtttctgat tatgcatcaa gggttactgg aagtaggtaa cgatgccgaa gaagattttg
    23221 atgtactgaa ttggttaggg gaagaagagt ccttctttat ggttatcgaa gtaaatgaaa
    23281 gtctatgtcg agaagccgaa accgtattgg aagaaattgg tgtggaaatg ccggatgcca
    23341 ttgaagtttt tttaaagcaa ctagtggaaa cgaaacaact ccctatagca gtaaatgact
    23401 agcataactg cttgaaattg gatcaatgaa atcctatgaa gcttttttcg attggaggtg
    23461 gaaaccataa aaatgtacaa agggcatcgt atacgggcag gagatcagca cttggtttat
    23521 cactttgttc ttggctggct actcgctctg ttcatcggtt ggatgagcgt cttttatttt
    23581 caagagctta gacaatttga tatttctaag ctatcacttt ctactataga aatcgttcgt
    23641 tctataaaag atttaatcta tttgctagga agtctcgttc tttcaggaag cacgatgttg
    23701 ctttatatac acttttttca ggatcattgg cgcagtttgt ggcatcgaca aaagctagcc
    23761 cggatgattc tagaaaatca ttggtacgaa gtaaaacaaa ctcagagtga aggatttttc
    23821 aaagacctca atagtagtcg aaccaaagag acaatcagtt acttccccaa aatctattac
    23881 cgtatgaagg atggtttact ttctattcgc gttcaaattt cactgggaaa atatcaagat
    23941 cagcttttaa agctggaaaa gaagttagaa agtggtctat attgtgaact agtagaaaag
    24001 gaactcaaag actcctatgt ggagtacact ttactgtatg atataattgc caatcgaatt
    24061 gggatagacg aagtagtggc agaaagtggg gctttgcgat tgatgaaaaa tcaagtatgg
    24121 gcttatgatt ctttacctca tatgttaatc gctggcggca caggtggtgg gaagacttac
    24181 tttttactca ctatcatcga ggctttatta aaatctgatg ccgagctttt tgttcttgat
    24241 cccaaaaatg cggacttagc cgatttaggt acggtaatgc ctcatgtcta ttcccaaaag
    24301 gaggaaattt ctgcttgtgt ggaagatttc tatgagcgca tgatgactcg tagcaaggca
    24361 atgaaagaaa tgcccaacta caaaacagga gagaattatg cgtttcttgg acttccacca
    24421 aactttttaa tctttgatga atacgtggtt tatatggaaa tgttaacgac gaaggaaagt
    24481 gcggtgattt tgaataagct caaacaaatc gtgatgttag gtcgtcaatc tggtttcttt
    24541 ctgattctag cttgtcaaag accggatgcg aaatatttag gagacgggat tcgcgatcaa
    24601 tgtgcgacat gtttctaact gaaaaggtta ggcacttaaa agaagaaaac ataagtttcc
    24661 ttttaaggag aactgatatt ttgagcagtg gaatgatggg gtaacgccct gaaacgctcc
    24721 cttaatactc cgactggctg tttaacatat agctgttaga tggtcagaag ctcggtgaag
    24781 tcggctgaaa gttaccgtaa atatgataaa ttcatatacg aaagttgttc agaggtgaat
    24841 gatgtaacct ataggtcgga ggtctataaa atactcacgg tgagaatgta agtaatacta
    24901 ctgacgaact tgcgaatgaa agaatctata cacggactgt atagaaatgt acaggattct
    24961 accgtatcaa cggaacagaa tgtatgttgt ggtttagtaa gattattggt tatgaacaac
    25021 catgcaatgt tacaggcatt ggaaatatac aggttcaaag caagcaccta aaagtatata
    25081 taaagataaa aatatcgaaa catgggaagc tggcaatgtg gaggaaacta tattccattg
    25141 aaacatttgt gacgaagaat aataagcaca tttatgccag tgaaagtggt ggcacagtac
    25201 caatgaggat atagaaatat atcggaggaa tagccactag tcaaaagaaa tcgttaatta
    25261 aatgatgtat ttcatagaat cgagtaagac aaaataaaca ctacaaccta agtaaacaaa
    25321 ggtagtggtg ctatgaataa agtaaaaaca aataaaacac ttcgtcatag tgaatactat
    25381 ggcatgacac aaatatttga tgaactgtat gtaaaaagtg ataaaaaaga agtttttaca
    25441 gagctcatga caattattat gagtgatgaa aatattcgac tagcatacag aaatatcaag
    25501 aataacaagg gcagttatac agcgagtacc gataagaaaa gtattcgaga cattaaaaca
    25561 ctgtcagaag atacctttct aactgaggtt aaagttcttt ttcgctgtta caaaccacga
    25621 gcagttagac gtgtagaaat tcccaaacca aatggaaaaa cacgccctct gggcattcca
    25681 tcaatctggg ataggttaat acaacagtgt attttacaag tcttagaacc gatatgcgaa
    25741 gctaaatttc acaattatag ttatggattt cgaccaaacc gttccacaca tcatgcgatt
    25801 gctacctgca atcgactggc aaataggggg aagctacact ttgtagtaga tgttgatatt
    25861 aaaggattct ttgataatgt caatcactct aaacttttgc gtcaaatgtg gacgattgga
    25921 atccgtgata aatggctatt aggtattatt cgatccatgc taaatgctcc tatagtccta
    25981 ccaaccggta aagtcgaaca ccctaaaaaa ggtgtacctc aaggtggtgt cctatcccct
    26041 ttactatcta atatcatatt gaatgaatta gattggtggg ttgcttcaca atggcaaaat
    26101 accacgattg agacagaaaa gattatggat aggcgagata aaggcaaagg cattgataag
    26161 actaatcagt atcgggcatt aagacgaaca aacttaaaag aaatatacat tgttcggtat
    26221 gctgacgact tcaaaatctt ttgtagaaaa cgaagtcatg cagataaaat atttcacgca
    26281 acgaaaatgt ggcttaaaga acggttatca cttgaaatta gcgaagaaaa atccaaaatt
    26341 gtcaatctca aaaaaggtaa atcagaatat ctaggatttg aattaaagct aatcaagaaa
    26401 ggtaaaaaat acgtagtcga aagtcatatg agcaaaaaat caatgacaag agttaaaatc
    26461 caattaaaga aacaattacg taaagttgcc agaccgaaga atcattgcga acaagcaaaa
    26521 gaaattggat tatataattc tatggtgatt ggaatccatc aatattatgg aattgcaacc
    26581 tgtgtaaatc tcgattgcag taaaatagcc tatacactaa aaccgttcat caatcacaaa
    26641 ctgccgacaa agaaacatgg aaagatatta aatacattta tcaaatcgaa gtatggaaaa
    26701 agtaaagaaa tgcgatggtt gaataatgtg ccaattgtac cgctcaacta tgttcagttt
    26761 agacttgctg tccccctatc agagggaact tgcaagtaca ctgaaagtgg acgaagcaag
    26821 atacacagta aattaaaatt agacctagcc cttttacttc acatgatgag aaatagtaat
    26881 tatgaaagaa gtattgaatt tgtggataac agaatatcta aatattctgc tcaaaaggga
    26941 aaatgtgcta tcacgggtaa atttctcgaa tacgaagaaa tccattgcca ccatatcgta
    27001 ccagtaaaac aacagggtac agacaaatac agcaacctca ttattattca caaaaatgtt
    27061 cacgcattag tccatgctat cgaagaaaaa atcatacaca aatacctgaa tgtattaaat
    27121 ctaaccaatg aacaaataga aaaactaaat gaattacgtg tcaaagctgg taatagtgtt
    27181 ttaacagttt aacttgaaaa atatatcata cttaacattc ttttgatgga acgccgtatg
    27241 aagtgaaagt ttcatgtacg gtgtgaagcg ggggaaaatc tggagatgac atcaaaggat
    27301 tacctatcgc
//
LOCUS       DARPZF010000032        26957 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.033, whole genome shotgun sequence.
ACCESSION   DARPZF010000032 DARPZF010000000
VERSION     DARPZF010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26957
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.033"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            123..1127
                     /locus_tag="SLE65_001758"
     CDS             123..1127
                     /locus_tag="SLE65_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8449052.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            1128..2072
                     /locus_tag="SLE65_001759"
     CDS             1128..2072
                     /locus_tag="SLE65_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8449053.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            2072..3034
                     /locus_tag="SLE65_001760"
     CDS             2072..3034
                     /locus_tag="SLE65_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8449054.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            3061..3975
                     /locus_tag="SLE65_001761"
     CDS             3061..3975
                     /locus_tag="SLE65_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8449055.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            4001..5782
                     /locus_tag="SLE65_001762"
     CDS             4001..5782
                     /locus_tag="SLE65_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEI8449056.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            6130..6816
                     /locus_tag="SLE65_001763"
     CDS             6130..6816
                     /locus_tag="SLE65_001763"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEI8449057.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            6836..10417
                     /gene="smc"
                     /locus_tag="SLE65_001764"
     CDS             6836..10417
                     /gene="smc"
                     /locus_tag="SLE65_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEI8449058.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            10426..11235
                     /locus_tag="SLE65_001765"
     CDS             10426..11235
                     /locus_tag="SLE65_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEI8449059.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            11246..12244
                     /gene="ftsY"
                     /locus_tag="SLE65_001766"
     CDS             11246..12244
                     /gene="ftsY"
                     /locus_tag="SLE65_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEI8449060.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            12431..14698
                     /gene="gshAB"
                     /locus_tag="SLE65_001767"
     CDS             12431..14698
                     /gene="gshAB"
                     /locus_tag="SLE65_001767"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HEI8449061.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(14787..15239)
                     /locus_tag="SLE65_001768"
     CDS             complement(14787..15239)
                     /locus_tag="SLE65_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEI8449062.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKSNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            15389..16339
                     /locus_tag="SLE65_001769"
     CDS             15389..16339
                     /locus_tag="SLE65_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEI8449063.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            16332..17291
                     /locus_tag="SLE65_001770"
     CDS             16332..17291
                     /locus_tag="SLE65_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEI8449064.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            17288..18043
                     /locus_tag="SLE65_001771"
     CDS             17288..18043
                     /locus_tag="SLE65_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8449065.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            18066..19019
                     /locus_tag="SLE65_001772"
     CDS             18066..19019
                     /locus_tag="SLE65_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEI8449066.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(19663..19959)
                     /locus_tag="SLE65_001773"
     CDS             complement(19663..19959)
                     /locus_tag="SLE65_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HEI8449067.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            20314..20670
                     /locus_tag="SLE65_001774"
     CDS             20314..20670
                     /locus_tag="SLE65_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HEI8449068.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            20680..21579
                     /locus_tag="SLE65_001775"
     CDS             20680..21579
                     /locus_tag="SLE65_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HEI8449069.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            22096..22827
                     /locus_tag="SLE65_001776"
     CDS             22096..22827
                     /locus_tag="SLE65_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HEI8449070.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            22972..24999
                     /locus_tag="SLE65_001777"
     CDS             22972..24999
                     /locus_tag="SLE65_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEI8449071.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            25107..26204
                     /locus_tag="SLE65_001778"
     CDS             25107..26204
                     /locus_tag="SLE65_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HEI8449072.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            26511..>26957
                     /locus_tag="SLE65_001779"
     CDS             26511..>26957
                     /locus_tag="SLE65_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8449073.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT         9042 a         4665 c         5688 g         7562 t
ORIGIN      
        1 taattattaa taattcatta cacaaagata agaataacct ttgttataaa acgatttatt
       61 ctgtgtaatg tcctttttta ttaagaaaaa cttccattta ggaagcagag aggggtattc
      121 gattgtccga taaccaatta ttagaagttc agaacctaca tacaggattc cgactcaaag
      181 atgactatta cgatgcagta gatgacgttt catttacttt agacaaaaac gagattttag
      241 caatcgttgg ggaatctggg tgcgggaaaa gtaccttggc tactacgatt atgggattac
      301 ttgatcctaa taacacaaaa attacaggtg agattttata taacgatctg aatttaatcg
      361 acctgaacga aacgctctat aataaaatcc gcggaaatga tatcggaatg attttccaag
      421 atccgttgtc tgcattaaat cctctcatga gaatcgaaga ccagatcaaa gaaggacttt
      481 cctatcacac aaagatgaat gcagaacagc gtcaagctcg tgcactagaa ttgctagaac
      541 aagtagggat tcctaatcct gcgagagttg gacgccaata tccccatgaa ctatcaggcg
      601 gtatgagaca acgtgtcatc atcgcaatcg caatcgcctg caaacctcca atcgtcattg
      661 cagatgaacc gacgacagcc ctagatgtaa ccatccaagc acagattctt gatttactga
      721 aagaccttca ggaagaaaca aaaacaggga tcatcttgat cactcatgac ttaggagtcg
      781 tagcagaaat ggctgatcga gtggcagtga tgtatggcgg acagttcgtt gaagtagcag
      841 gtgtaaaaga actgtttgat catcctaagc atccttatac acgctcttta ctgaactcta
      901 taccacaaga aggaaatcat gatgcagaac tccatgtgat cgaaggtgtc gttccttctc
      961 tgaaaaacat gcctcgtaaa ggttgtcggt ttgcaccacg tattccatgg ataccagcaa
     1021 gcgatcatga agaagagcct atccttcatg aagtcgcacc gaaccacttg gtacgttgct
     1081 cctgctataa gcatttccac tttagagacg aaaaaggaga ggtgtagatg acagaattaa
     1141 tcacaatcaa agacctgaaa gttcattacc ctattcgcag tggattcttc aatcgagtaa
     1201 cggatcatgt atatgctgta gatggtgtgg attttattat cgaaaaagga aagacatatg
     1261 gtttagtggg agagtctggc tctggaaaat ctactacggg aaaagccgtt gtgggattag
     1321 aaaaggtaac agccggacaa atcatgtatg aaggaaaaga tgtaacgaag cgaagcaacc
     1381 gcaaaaaaat gggttataac aaggatgtgc agatgatctt ccaagattca atgtccagtt
     1441 tgaatcctaa aaagcgagtg ttggatatca ttgctgaacc catccgaaat tttgaacggt
     1501 taagcgatca agaagaaaag aaaaaggtaa aaggactgct agatatcgtt gggatgccgg
     1561 aagatgcgct atataaatat cctcatgaat tttcaggcgg acaacgtcaa cgtctaggag
     1621 tagcccgtgc tgttgctacc aatccaaaac tgatcgtagc cgatgaacct gtatctgctc
     1681 tggatctatc tgttcaagcg caagtattga atttcatgaa acgaatccag caagaatacg
     1741 gcctcagcta tttattcatt tcacatgatt taggtgtagt aaaacacatg tgcgacaata
     1801 tcgcaattat gtacaaaggt cgatttgtag aaatcggtac aagagaagac atttataatg
     1861 acccgcgaca tatctatacg aaacgtctgc tttcagctat tccgcaaatc gatgtagaaa
     1921 atagggaaag ccacaaagaa aatcgacgaa gagtagaaca agagtatatc caaaaccaaa
     1981 aagaatacta tgatgcgact ggtcgagtct acgatttgcg tacgatcaca actacacaca
     2041 aagtggcgtt gaaagatgga ggtgcaagct aatgtggaaa acgattctgc gacgtgtttt
     2101 attgatgatc ccgcaagtta ttattttaag tgttctgatc ttcttattag cccaagcgat
     2161 gccgggggat ccatttaccg gtttgatcaa tccaaatcag gatccggcag tgatcgaaca
     2221 gatgcgacaa gcagctggct tgaatgaccc atggtatgtc cagtacttcc gttggatcgg
     2281 aaatgctttg caaggcgatt ttggtcaaag tttcttatac aaacgctctg ttgctgactt
     2341 gatcggcgaa cggatcatca acactttata tctatcgatc ttgacagttg tccttactta
     2401 tttgattgct gtgcctctgg ggatgcttgc tggccggtat caaaattcaa tcttggataa
     2461 gattgtcgta atctacaact tctttagttt tgctgttcct ttatttatct tcggcttgat
     2521 catgctattt gtttttggtt atcgtttagg ctggttccca acaagtggat cacaaacact
     2581 aggtttgcaa ggtggattta tcactcaatg gatagaccgt ttgaaatata ttctgttacc
     2641 atcaattacc caagcatttt tggcgactgc cgtcacaatc caatatctgc gaagtgaagt
     2701 aatcgattcg aaatcgctcg attttgtcag aacagcccgt tccaaagggg taccgacgaa
     2761 taaagtattc agtcgacata ttttccgaaa tgcagcgttg ccgatggctt ctcaaatggg
     2821 gtatgaaatc acttcgttga ttgctggttc tgtagttatc gaaaagattt ttggttatcc
     2881 gggagtcgga aaactattta ttgattccat cggccaacgg gactataccg tgatcacatc
     2941 cttagtattg attttaggaa tcgcgacgct agtggggaca ttactttcag atatcatcat
     3001 gagtatcgtt gacccgcgta ttcggattca ataaaaccaa tcagaaagga gaatggatcg
     3061 atgagtgaaa aaaacaatac agcagttcaa gaaagtattc ctcctatggg gatacgaatg
     3121 attgctcgag aatttaaaaa agataaaatt gctatttttt cattaggttt gctagtggtt
     3181 ttattattag tgatctttat cggtgcgatg ctgaccgatc aagacaaagt gatgtatgtt
     3241 agtatcttcg acaaatacgc tgcaccagga acagtttcga cacaaggaca aaagttcatt
     3301 ctgggagcag atgaaggcgg acgtgatgta ttaggacaat tgatcatagg tgctagaaac
     3361 tctgttacga tcggatttgc gatcacgatc cttacttcga tcatcggggt tggattaggg
     3421 atcatctctg gctactacgg agggatcatt gacaacatct tgatgcggat cgttgatttt
     3481 atcatgattc taccgatcat gctgatcatt atcgtcttcg tatcgattat ttccagatac
     3541 aatgtctggt cctttatatt catcatgagt gcattttatt gggtagctaa agcccgatta
     3601 ttccgaagca agacattatc tgaagcaaga agagattatg tcagtgcctc aaaaacaatg
     3661 ggaaccaatg attttaaaat catgttccgc gaaatcatgc cgaatctaag ttcattaatc
     3721 attactaatt tgacgatgaa ctttgcggca aacatcggta tcgagacaac tttgactttc
     3781 ttaggtttcg gcttgccggc aaatgtacct agtttaggta cattgatcgg ttatgcaagt
     3841 aacggagaag tcttagtgaa tcggcaatgg atctggttac ccgcatcaat ccttatttta
     3901 gttttgatgt tgagtatcaa ttatgttgga caagcattca agcgttctgc agatgcgcgc
     3961 caacggttag gctagtatag aagcgaaggg ggaaatagga atgaagaaaa cgatttttgg
     4021 atttgcagcg ctgatgtctg ctgtcgttct tgcagcatgc gggggcggag gtacagatac
     4081 ctctggaaac aactctggag gcaacggcaa taacaaagag gaattaactt ttccaattgc
     4141 aacaaaaaat aatgatgatg caatcgaaga cggcgaatta gaagctgcgg tcgcaacgga
     4201 cagtcagttt aaaggattgt tccagtggga gttttaccaa gattcatatg atgcagcttt
     4261 tatggctcct tctcatgaac cgctatttgc aaacgatgac gatttcagaa tcacagacga
     4321 cggagctgca acgcttgatc tagatgaaga tacgaaaaaa gcgacaatca aagtaaaaga
     4381 caacgtcaaa tggtcagatg gtgaagatgt aacggcggac gatgtgattt tcccttacga
     4441 aatcattggg aataaagatt acactggtat ccgttatgac gacactttcc gtaacatcgt
     4501 aggtatggaa gaatatcatg atggaagtgc cgacacaatc tccggaatca aaaaaataga
     4561 cgacaaaaca gttgaaatcg aatataaaga agtaaaccca agcatgcttc aatcgggtgg
     4621 tggtatctgg tcatatgcag caccaaaaca tacgttagaa ggtgtagcaa tcaaagatat
     4681 ggaatcaagc gatcaagtac gtaaaaatcc agtgactttt ggcccttatt acatgagtaa
     4741 tatcgttgca ggagaatcag tagaatactt gccaaacgag cactactgga atggtacgcc
     4801 taaattgaaa aagatcacga tgaaatctgt accgatggca agtgcaactg aagcattgaa
     4861 ctctaaatta tatgatatga ttttccaaat gccaacagat acttacgata cctataaaga
     4921 aattgctggc tatacaaact taggccgtga acaaacttct tatacttatc taggattcaa
     4981 gttaggtaaa tggaatgcag atacaaagag tgtggaatac aatccagatt caaaaatggc
     5041 tgataaatca ttacgtcaag caatgggcta tgcattagat aataatgcag taggtgaacg
     5101 tttctatgca ggtttgagaa gcaatgcgac ttcattgatt cctccagtat tccagtcata
     5161 ccatgatgat gagatgaaag gattcacaca agatctagac aaagcgaaaa aactattaga
     5221 tgatgctggc tacaaagatg tggatgacga tggtttaaga gaagacaaag atggaaataa
     5281 actaacaatc aactttgctt cgatgtccgg tggggaaaca gcgcaaccat tggcagatta
     5341 ctatatccaa caatggaaag aaattggttt ggatgtccaa tacacaacag gtcgtctgat
     5401 cgaattcaat tctttctatg ataaattaga aaacgatgat cctgaaattg atgtttacca
     5461 agctgcttgg aatacaggaa ctgatccaaa tccaagtgga ctatggggac caaatgctgc
     5521 gttcaactac actcgttatg aatcagaaga aaatacaaaa ttgatcaacg atatcagttc
     5581 aagcaaagca tttgatgaag agtaccaaaa agaagcatat caaaaatggc aacaatatgc
     5641 atttgaagaa gcatttgcga ttccaacgtt gttccgtaat gaagtattgc cagtcaacga
     5701 ccgtgtcaaa gactgggatt ggtcttatga tgtaccaaac ccatgggcaa atgtttctgt
     5761 tacagcagat tcacgttcat aatcactaaa aatgaccgaa aaagggcgat gtcctttttc
     5821 ggttttttga tatttttctg tttatttctc taatattcag gtcaaggcgc tgatttcatg
     5881 acttctccaa taaacggtgt tcaaagtcca gtttctcggt attaagtcaa atttatgcaa
     5941 aaatatggaa agccattttc acaaaatttt ttcttcatac tcgaaactaa acgaattttt
     6001 cacaacttct cgtcaatcac taggattatt aaagctttac ttaccttttg accgaaccat
     6061 ttcaaatttg acaaaaaacc agtataataa ggaagtatcg aaaaaatatc cataaaagga
     6121 atgtggaaaa tggacaacca gctgacaaaa gaactaaaag aaaactataa catcgttttt
     6181 cacgatctaa atttgcttga acaagctttt acccattcat cctatgtgaa tgagcatcgc
     6241 aatctgcaat tatcggataa tgagcgactt gaatttttag gagatgccgt tttagaactg
     6301 atggtttctc agtatttatt ccgtttatat cctcatttgc cagaaggaaa attgacaaaa
     6361 acacgagctg cgatcgttcg cgaagacagc ttgtcgaaat ttgccaaaga atgtcacttt
     6421 gatcaatatg ttttgttggg caagggagaa gagaattcag gaggacgtac gcgaccagca
     6481 ttgctttgcg acctattcga agctttttta ggcgcgttat atcttgacca gggattcgac
     6541 acgacccatg cattcatcga aaaagtgatt tttcctaaag tcaaagcagg tgctttttca
     6601 catgagatgg atcataaaac aaaactacaa gaagtcttgc aaaaatcagg tgatgtatca
     6661 atcgaatacc gattgatcaa tgaagaaggt ccagctcatg aacgagtatt ttggatcgaa
     6721 gtttatgtag atgatcaatt gattggcact ggacaaggga aatcgaaaaa attagcagaa
     6781 caagctgcgg cggaaaatgc attggcagca ctgtaaaagt aagtgaggga aagctttgta
     6841 tttgaaacga attgaaatag ccggttttaa atcatttgca gacaagacag tcattgattt
     6901 tgaaaatagc gtcacagcag tggttggacc aaatggcagc ggaaaaagca atattacaga
     6961 ggctatccgc tgggtattag gagaacaatc tgctaaaagt ctgcgaggcg gaaaaatgcc
     7021 ggatatcatc tttgccggtt ccgatacccg taagcagctg aatattgcag aagtcacagt
     7081 gattttagac aatagtgatc attatctgcc attggagtac aatgagatca gtgtaacccg
     7141 ccgttatcga cggactgggg aaagcgagtt tttcatcaat aaacaaagct gcagattaaa
     7201 agatatccaa gaattgttct tagattctgg attaggaaaa gaatcgttct caatcatttc
     7261 tcaaggaaaa gtagaagcga ttttcagtag taaaccggaa gaccgtcgtg ggatctttga
     7321 agaagcagct ggtgtcttga aatacaagca gcggaaaaag aaagcagaac agaagctttt
     7381 tgaaacagaa gacaacctca gccgcgtcca agacatcatc cacgaattgg aagaacagtt
     7441 aactcctttg gccgcccaga gtgaggcagc aaaggagttt ttacggctaa aagaaacact
     7501 gactcaaacc gatgtctctt tgatggttgc tgaaatcaag acagcaaaaa aagattggga
     7561 caacaaacaa gcacagcttg cgaaattcaa tctagaatta ggcaaactat ctgagtcgat
     7621 ccaagaacaa gaatccattt tggcgaagca gcgtaaagaa aatgcgcaag ccgatcgtct
     7681 gatcgaaaaa aatcagcaag tattattaga tctttcggaa aaactgaagc agacagaagg
     7741 acaaaaagat gttttgcagg agcggacaaa gcatacacaa aaaagctcgc aagaatatca
     7801 aacttcatta gcagaagcac aaaaaaaggt taaacatttt gaaaagcttc aagaaagctt
     7861 gatgaaagca gcagcagaaa aagaaacaga gatccaaaaa gctgaagcaa atctcataaa
     7921 aacacagcaa gaattagaaa aataccaaaa atcaacgaaa gaattattgg cagaattaag
     7981 agatcaatat gttgatttga tgcaagaaca agcagctgta ggaaacgaac tgaagtatct
     8041 agaacgtcaa tatatacaag aaacagcaaa aagcaagcag acgttagcca agcaatcgga
     8101 agtagaagca tcagtagacc gattgatctt acaaaaagaa gaattgacac aaaagcaggc
     8161 gcagctaaaa tcatctttaa ctgaaacaaa agagaagtta gaaatgatcc aacaaaacgg
     8221 gaaaaagttc caagaagcat tagcaaaaga acagcctaaa atgtatcaat taatgaatca
     8281 agtccagcag ctacgtgctc gtaagaaaag ccttcaagaa atccaagaaa actattttgg
     8341 tttttaccaa ggggttcgat tggtcttgca gcataaacag cagctttcgg gtattgtcgg
     8401 agcagtggct gaactgatcg atgttcctgc agatttcacg ttagctatcg aaacagcttt
     8461 aggtggggca gcccagcatg tcatcgttga aaatgaaaaa gatgctcggc aagccatcac
     8521 gtatttgaaa cagcaaagag gaggaagagc aacattcctt ccactgacga caatcaaacc
     8581 aagacaatta ccggctcata tattgacaca agcagcagct gtagaagggt ttatagggat
     8641 tgccagtgaa caagtcagtt atcccgatca aatccaaact gtggttcaaa acctgctagg
     8701 aacgatcctt ttagccaaag acttaactag tgccaatgca atcgcgcaaa cgatccgcta
     8761 tcaatatcga gtggtttcct tagaaggtga tgtgatgaat gccggaggat ccatgacagg
     8821 tggagcgaat aaacgaggaa accaaggcag tttgtttgta caaaatcaag aattgaaaca
     8881 gttgactagt gaatttgaag aagcagataa acaactccaa gcacaagaaa aaaaagttca
     8941 ggagctgcaa caagaaacag ctcgtttagc cgaagaacaa gaagttttgc gtacacgagg
     9001 cgaacaatta cgttttgaag aacaagaagc gacaaatcag ctacaaaaca tcataaatga
     9061 acttgaacgt tttgaaaaag aaaagcaaat ctcaactttt gagacacgtg aactgcagca
     9121 gtttatcgaa gattacgaaa agcaaacgaa cgaattgaaa gacaaacaaa cagatcttga
     9181 atcgcaacga caaaaaatcg acgaagaaat caaatcgtta agtcaagaaa gcgaccagat
     9241 ggaagccaga agagcacaag tacaaagtca aaaagcacaa gaacaagcag atcttgctgt
     9301 cttgaaagag cagtttaatc atctgcagat ccagctccgc ggtgcccgag tccaaaaagc
     9361 agaggcaacc gaacgtcaag aagcgataga aaagcagttg gcgacattga cagcagactt
     9421 ttctgatcat gaagtcacag aagaaagttt ggaaaaacaa attaacgaat tatctgctca
     9481 gcgagaaaca ttaaaagccg agttggcaaa agccaaagag cagcgagata gaaggcaaaa
     9541 ggagatcgat aagcttgaag cagtcttggc agagcgtaat cgtgagcaaa aagcacgact
     9601 gtcggaacaa tccaaattag aagtccaaaa agaccgagct gaaatgattt tagataatca
     9661 tttgacctat ctgcagtcag aatatcagct gacatttgag aaagcttccc aagactatca
     9721 agaaacaacc gatatcgaag acagtagaac aaaggtttca tccttaaaag aacagattga
     9781 aaaactggga ccagtaaact taaattcaat cgaacaatac gaacaagtca gtgaaagaca
     9841 tacattctta gcaacacagc gagatgatct gttagcagcg aaaaaccaat tgtttgaaac
     9901 gatggatgag atggatgatg aagtgcggac aagattcaaa gaagtatttg aagctatccg
     9961 tcaagaattc aaaattgtct ttccaaatat gtttggcggc ggtaaagctg aattagtact
    10021 gacggaacca actgatttgc tgaaaacagg tattgagatt gaagtacaac ctcctggcaa
    10081 aaaactgcaa agtctaagtt tgctttctgg aggagaacga gcacttacag ccatcgcgtt
    10141 gctcttttcc attatccgtg tctgtcctgt tccgttttgt atcttagatg aggtagaagc
    10201 agcgttagat gaagccaacg tgaaacgttt tggtcgttac ttgagcgatt tccaagatga
    10261 cacacaattt atcgtagtca cacaccgcaa aggaacgatg gtcgcagcag atgtactgta
    10321 cggagtgacg atgcaggaat ccggtgtatc aaaaatcgtt tctgtacgga tggaagatat
    10381 caatgaagag gcgaaaatca acgaaacgaa agtgtaggaa cgaaaatgat caaattagta
    10441 gcaatcgatt tggacggtac attattaaat gaacaaaagc tgatttcaga tgagaataaa
    10501 caagcattag cacaagcaaa acagcaaggg gtcaagatcg ttctatgtac aggacgcccc
    10561 ttagctgcga tggcgcatta tctgcaagaa ttaggactgg tagatgaagg tgactacagc
    10621 atcactttca acggcggttt ggtacaaaaa aatgatactg gtgaaatcat ggaaaagaaa
    10681 gtgatggaag tatcagatat ccaacgctta tacaaactgg ctcagcaatt ggatctgcca
    10741 ctagatgttt tgtctgacaa tgtggtttta cagctgccta gtgccccaag gaagcaatcc
    10801 ttgtacaatg tgttgaataa gctgctgcaa ttccaaccag cggatataag cgatattaca
    10861 gatgaatttg tgcttaataa ggcagtaatc gcttatgacc aagaagaatt agatcctaaa
    10921 atcaaagaaa taccagcaga attccatgaa atgtatgaga tcatcaaaac aagaagtatg
    10981 cttttggaat ttatgccaaa aggtgttaca aaagcttatg gtatttcttt attggcaaaa
    11041 gatcttggtt tgaaacaaga agaaatcatg gcgatcggtg atgaggaaaa tgatttaccg
    11101 atgatccaat atgctggact aggcgtagcg atggagaatg ctgtgccttt cgtcaaagaa
    11161 gcagcagatt tcgtgacagc cagcaatgaa gaaaatggcg tagccaaagt gatccaaaaa
    11221 tttgtattag agtaggggga gtcaaatggg attttttgat aaaatcaagc gtgcttttac
    11281 tggcgaagag aaaacagaag aagttgaagt acaggagaag tacgacaagg gtttagaaaa
    11341 gacgcgtaaa acatttggtg aacggatgaa tgagttgttt gccaattttc gaacagtcga
    11401 tgaagacttt tttgaagaat tagaagaaac acttatcggt gcagatgtag gttttgaaac
    11461 agcgatacga attaccgaag cattacgtca agaagtgaaa ctcagaaatg cgaaaaaatc
    11521 ggcagaagtc caaaatgcga tcatcgagaa acttgtggat ctctatgaag cggaaggaat
    11581 caatgaagta aatgaactaa atatccaaga agacggacta acagttattt tgtttgtcgg
    11641 tgttaatggt gtagggaaaa caacaagtat tggtaaactt gcccatcagt tcaaaaacga
    11701 aggtaaaaaa gtattgatgg cagcagcaga taccttccgc gctggagcaa tcgaccagtt
    11761 agttgtctgg ggcgaacgcg ctggtgttga agttgttcgt ggcaatgcag gaggcgatcc
    11821 agcagctgtc gtattcgatg ctttggaaag agcaaagaca gagcaggcag atgttttact
    11881 agttgatact gcaggccgac tgcaaaataa agtgaacttg atgaacgaat tagaaaaaat
    11941 aaaacgagta atccagcggg aattaccaga agcaccccaa gaaacacttc ttgtattaga
    12001 tgcaaccact ggtcaaaacg cgatggttca agcaaaacaa ttcaaagaaa caacagatgt
    12061 gaccggtctt gttttgacaa aattagatgg tacagcaaag ggcggtatcg tacttgctat
    12121 ccgtaatgaa ttgcatttac cagtgaaatt ggtcggtctt ggtgaaggaa tcgatgactt
    12181 ggagccgttt gatccaaatg attttgtcgt tggattgttc aaaggattac taaaagaaga
    12241 ataacccatg tctaaaaagc aggagctgtg acaaaagttg cagctccttg tttgaatgat
    12301 tgtttttaac atagctgtgt ttttgatgcc ttcattttta tacttatttg taagcggttc
    12361 tcaaacaatt tcgttctttt tcttagactt tttgattata attagattca tatgaattgg
    12421 aggtcactta atgatgaatt ttaagcaatt attattgcat gtcaatgcgc gcccttttat
    12481 cgaccaagct cgatttggta tagaacggga aggacagcgg gttgatcttg caggaaatct
    12541 agcaaaaacc gatcatccag caatctttgg cgatcgatcc tatcacccct atatccaaac
    12601 agattttagc gaaacacaaa cagagatgat cacccctgtt accgattcta ttcccgaatt
    12661 atttcagtat ctcgctgctg tttatgatgt gactgctcgt tctataccga aagaagagat
    12721 gatctggcca ttaagtatgc cacctgcctt accggaaaaa gacgaagaga tcattattgc
    12781 aaaattaaaa aatttcgaag atgtcttgta tcgacgttat ttagcaaaag aatacgggaa
    12841 gcgaaaacag atggtaagcg gtattcattt caattttgaa tttggcgatg agttgctaag
    12901 aacattgttc agccatcagg aagaatttca agatttttcc gaattcaaaa cagaacttta
    12961 tttgaaaaca gcgagaaact ttatgcgcta tcgctggatg atcacttatt tattcggtgc
    13021 ttcaccaatg agtgagaaga actacttttt agatgaatca catccgcaag aacctgttcg
    13081 cagtattcgc aacagtgcgc tgggctatac gaatcatcca aatgtgaaag tttcctatgc
    13141 ttctatgaaa cagtatttag cagatatcga gcgaatgatc gaagaaggga aactttcgga
    13201 ggagaaagaa ttttatacac cgcttcgttt ccgaggcgga aagaaagtcg cagatttagc
    13261 aacaacaggt gttcgttata ttgaattgcg gaatatcgat ttgaatcctt atgcaagatt
    13321 gggtatcaat ccagagcaag ttcggttctt acaattattc ctgatgtaca tgttatggac
    13381 agaagaaaaa gaagactgtg accaatgggt agcagaaggt acgactcgaa ataacaaagt
    13441 agcactagaa caaccatcag atcaaacaga atttcatcaa gaaggtagag aaattcttga
    13501 aggaatgaag caaatgctgg ttgaattgga ttggttggat tctctttatt tagtagagga
    13561 agcattgact caaatggatc atcctgaaca aacgttagca gcgaaactct atcaagaagc
    13621 acagctatcg agtcagcaag aagttgctgt ggcattggga catcaatatt ataaagaaag
    13681 ccatgaacgt ccctatcagt tggccggttt tcgcgaaatg gaactttcta ctcagatatt
    13741 tatgttcgat gccatccaaa aaggtgtcca agtcaaagta ttagatgagt cggatcaatt
    13801 tttgcgtctg caattccaag accatgtaga atatgtgaaa aatgcaaaca tgacaagtaa
    13861 ggacagctat atcgtcccac ttatcatgga aaacaaaaca gtaacgaaaa aagtcttaaa
    13921 agaagctggg ttccgggtac caggaggcgc agaattttca tccatggaag aagcggtaaa
    13981 agcttatccg agatttgccg agcaggcatt tgtgatcaaa cctaaatcaa ccaattacgg
    14041 gttaggtatc acgattttca aggaaggagc tagtctggaa gattatcaag caggtttagc
    14101 cattgctttt cgtgaagaca gttcggtttt agtagaagaa tttatgccgg gaacggaata
    14161 tcgtttcttt gtgatcgacg gagaagtcca agccatcatg ttgcgagtcc ctgctaatgt
    14221 tattggtgac agtatccgaa cagtgaaaga acttgttgaa gaaaaaaata gtgacccttt
    14281 gcgtggaacg aatcatcgtg cacctttaga attgatccaa ttaggtgaat tagaacaatt
    14341 gatgttgaaa gaacaagggt tgacgatcga atcagttccc caagccaatc aaattgttta
    14401 tctaagggag aactcaaata tcagtacagg tggtgattcg atcgatatga ctgatgaatt
    14461 ttctgaagct tacaaaaaaa tcgccgtttc tgcggtagaa gcactaggag ctaagattag
    14521 tggtatcgat ttgattatac cagataaaga aatcgatcct acaactgata aaaaagcata
    14581 tgggatcatc gaagcaaatt tcaatccagc catgcatatg catgtttatc cttttgcagg
    14641 aaaaggcaga agattgacga tgaatgtatt gaaattgtta tatcctgaag tattttaaaa
    14701 gaaaaagctt ttgacagatt gtcctatttg atgtcaatct gatcaaaagc tttttttgca
    14761 tgtaaaaatt tatgtgtttt ttcgttttaa aataaacgat cccagaagct ttttttcttt
    14821 tttggttttt ctttttcagc tggcgaagag ttttcttctg ggtatttttt ttcgatatca
    14881 atcacaggtt catttactgc ttcttttgct gttaagagca atccgaattc ctcaggattt
    14941 gcagtgacgt aatcgttgac tacagtgaaa cggctattgc ttttcgttgc tagctggata
    15001 tattggtttt ggacagaaag gggtagagcc ccattcaaga gtatggaagc atctggatgt
    15061 tttttgagtt cttttaaaaa gttttctttg ttttttggtt ggatcatttc agcaacagtc
    15121 atactaagat agcagcgttc cctgaatgtc cctaaatatt tatgctgttc ttcagggttc
    15181 actaaaggtg taccataaag tcccttatcc aaatggcttt ttacatcatc ttgtgccata
    15241 aaaaataccc tccttcttct ctttgtcttt cttacgatta tagcatattc ccaataatac
    15301 ctaaaacata tgaaaaagcg gttgcttttg ttcaacgatt cacttaaaat aagaatgaaa
    15361 atcattctca attagaaagg tggattggat gcgctacgga cgactagtag cattattagt
    15421 tattttaagt agtatttcat tgttcatcgg agtatcgaat gtacaattgt cagaactgct
    15481 ccagttagat gggcaaagct tacaaatctt gctagtgact cgtttgccac gaacgatttg
    15541 tttgatcctt gtgggagcga ccagtagtat ttgtgggttg atcatgcaac atttgaccca
    15601 aaataaattt gtttcaccaa cgactgcggg cacgatggat agtgcgcgtt taggtatttt
    15661 agtggctatg attttcctac ctggtgcatc cttgattgtc cgatccttga cagcattttg
    15721 ctttgctttt gcaggaacat tgcttttttt atcccttacg cgattgttcc tccagaaaaa
    15781 tcaattgatg cttccgttga ttggagtcat gttagggaat atcattggtt cagttgctac
    15841 tttttttgct tatcaattcc agttggtaca aaatatgact tcatggcttc aagggaattt
    15901 tgcgactgtg atacgaggaa attatgagtt attgtatgct gttgttccat tgttgctctt
    15961 ggtttggcta tttgcttacc gatttacgat cattggtctg ggcgaatcgt ttgcagtaaa
    16021 tctgggaata gattaccaga agatgcagtt tttaggcatt ggcttagtat cattggctag
    16081 tgcagtcatg ttgatcatgg taggaagcat tccttttatc ggagtgatca ttccgaatct
    16141 tgtctctaga atatatggag atcaagtgca caaaacaatt ggcgtaactg ctttagcagg
    16201 tagtttgttc ttagtatttt gcgatcttgt cgctcgcgtg ttgatttttc cttatgaaat
    16261 accagtcagt gtgatcgttg gaatcatcgg tggggctatc ttcctttatc ttctgataag
    16321 gggacgacga tatgcttaaa aaaaagccat ctatttttat tggtatgctt gttcttgttt
    16381 tatttgttac aggaatgtac ttgacgatcc atacatatgg aaactggcat tttgcatgtg
    16441 cattgaggag taagaaaatt tttgcattta tccttgtctc gctagctgtc agcagtgcca
    16501 caatcagctt tcagacaatt acgcataacc agtttttgac tccttcagta ttgggacttg
    16561 agtcgttata tgtccttgtc caaacggtcc ttttcttctt tatcggagga gtgacgatgc
    16621 ttcagcagac aggtacagtt tttttcttat tgaacgttgg gctgatggtc gggctgagtc
    16681 tattgttatt tttctttctt ttgaaaaaaa tgagagcgaa tcttttttta ttactgatgt
    16741 cagggatgat tttaggtacg ctttttggta gtgtcagtac ctttttacaa gtcatcatgg
    16801 atccgaatga atatgatttg cttcaaggca gattatttgc aagctttggc aatatccaga
    16861 gtcagtatct tttgcctgct tctttgatca ttatcggctg ctggtacctg ttatttcgat
    16921 atcgacatgt gctagacgtt ttccatctcg gaaatgaaca agcagtaaac ctcgggatag
    16981 acacagatcg ttttgaattt ttgattttat gttgtgtcag tcttttgaca gggacatcaa
    17041 cggctcttgt gggtccagtt acttttttag ggtttattgt cgcaaatatc agttatcgtg
    17101 tcttttctac ttatcgtcat ggtcagctat ttatcggaag ctttctggta gctatgctgt
    17161 ttctgacagg aggacagctc gcagtagagc agattttcgg ctggaataca acagtgagtg
    17221 tcgtcgttga atttgtcgga ggaatttatt ttgtcacaaa attgattcgc gaaaggaaga
    17281 gtatcctatg attgatttac aaaaggtcaa taaactgtac catggaaaat cagtggttaa
    17341 agatgtacag ttaacgattc ctgaaaagaa attgactgct tttatcggtc caaatggtgc
    17401 tggaaagtca acggtgttgt cgatgatcag tcgtttgata ccaaaagata caggtgaaat
    17461 ctatttagac cataacgaag taaaggcttg gaaatccaat gaattagcca aaaaattatc
    17521 gatcctacga caatcgaatg aaataaatgt ccaaatcacc gtgaaagaat tagtagaatt
    17581 tggacgattt ccttatacga aaggaaaatt gacgacaaaa gacgaggaaa tcgttcagga
    17641 atcactggaa caccttgggt tagaagaaat agcggatcaa tcgattgaca ctctttcagg
    17701 cggtcaactc caacgtgcgt atattgcaat ggtgctagcg caagacacgg attatatttt
    17761 actggatgaa cctttgaaca atctagatat gaattttgcg gttcaaatca tgcagatttt
    17821 aaaaaattta gtacaagaaa tcgggaaaac aattgttatt gttcttcatg atatcaactt
    17881 tgctgcaagt tatgcagacg aaattgttgc aatgaaagat ggacagttat ttacgcaagg
    17941 aacgacccaa gaaatgataa aaaaagatgt attggatgaa ttatacgaaa tggacatacg
    18001 gatttgtgag attgaaggcc gcagattctg tctttatttc taaaactaac attaggagag
    18061 aagagatgaa aaaattagta gtaggtatct tgattctagc atcatttggt ttagcagcat
    18121 gtggaaatag caacaacacc agtcaggcag acacaaaaaa aagcagcaca caaactgaaa
    18181 ctacattgac gataacagat agtaatggag accaaatcga ggtgccaaat aatccagaaa
    18241 aagtcgtcgt attcgacaat ggttctttag atacgatgga tgctcttggt gttggagata
    18301 aggtagttgg agcagctaca agcagccttc ctgagtatct ttcatcctat aaaaaagtag
    18361 aatcagcagg tggaataaaa gaaccagact tagaaaaaat taatcagctt cagccagatc
    18421 taatcatcat ttctggccga caaagagatt ttcaaaaaga tctaagtcaa attgctccga
    18481 ccattttcct ttctttagat gcgaaaaatc catgggaatc tttccagcaa aatgtcactg
    18541 ctttagggga gatctttggt aagcaagaag aagctaaaac tcaattagag gaattatcta
    18601 gtgcaatcga tcagacgaaa aagaaagcag aagctactga caaaaaagca ctagtcacac
    18661 ttgtgaatga agggcaatta tcagcctacg gatctggttc tagattcggt ttcatccatg
    18721 atttatttgg ctttgaacaa gcagatgatc aaatcgaagc atccactcac ggtcaaagtg
    18781 tttcttatga atatgtgctg gaaaaaaatc cggatatctt atttgtagta gacagaacaa
    18841 aagctattgg tggagacgac agcaaagatg atatttctgc caatgaactg gtagcacaaa
    18901 cgaatgctgg taaaaatcag cagatcatct cccttgaacc agatgtctgg tatttaagcg
    18961 ggggcggttt agaatcaatg aaactgatga tcgaagatgt gaatcaagca tttaaatagc
    19021 ataaataaca gaggattaaa ctctcatact atgtaacaat aatgtttctt acattcttaa
    19081 atagcaagag cctatcctca aagaagttat caaaaaccat ccgtaaaatc gtattgatga
    19141 ttttacggat ggtttttatt tatttgagaa atcttttttc aacgtgaatt cattatctac
    19201 atcatacggg ttgattctag aatggggagt ggcaaaaaat agtgtgatcc attttttcag
    19261 catcaagatc gcctcctttg atttgaatca aaggtacaaa gcgaaactta gataaaactt
    19321 aaatttagat atttttattt tgtaccgatc tcttctttaa acgatgttcc atctgctgct
    19381 tctcggcaat aagtccacta gactagaaaa tatgagaagc tattttctgt ccagcgttct
    19441 tattactcaa agcaaatcgc agttgtcaca atctcttcta aacgatgttc catctgctgc
    19501 ttctcggcaa taagcccact agactagaaa atatgagaag ctattttctg tccagcgttc
    19561 ttattactca aagcaaatcg cagttgtcac aatctcttct aaacaatgtt caatcagctg
    19621 accttcggta ttagctcaaa gcactgattt cacaacctct atttaggcat gtgtctcagc
    19681 aagcggttga tagttgatga tctgcatttt tcgataaaaa tcggcgggaa gcttactcca
    19741 ccgttttaat aattgataga aataactctc ttctgctttg attttatact cgcttaatat
    19801 caatccaaaa ctattcgttt tttttgaagc taatttttta taaatatcca atgctttggt
    19861 tttatcttca ttgacaaaga gtgtttttac ttcaatataa gaaccctcga tattttgtgt
    19921 ttcttcgata aaatagatgt tttttatata ttccttcata gtgattcctc caaagaagtc
    19981 ttttatttga taagtttact ctaccgaaga gttgttaata atccgtgaac aaaaagtaat
    20041 tctttttcca atagttgtta aaggtttttt attttttata gtattttttg ttatttaaga
    20101 aaggaataag gttaaacaaa taacaggttg ctttttgggt ctttttccgt tcaagaaact
    20161 gaacgaagaa aagggaaagt tgtctctttt gtgataagag aaatcataat aaacgaatga
    20221 cttactttcc aataaattga gaacagtcag aaccagacaa attagttgca tctgatgaat
    20281 aaagtgatta ttctatgaca tgaggtgata cagatgaaat tagaagtgac aaaagaagca
    20341 caagaagtat tgaagaataa attagaagca gacgatcaac ttttattaga tatcgaaaac
    20401 ggtgacggtc catttgcaga aagccaagtc agttgccaat tggatacggc atttcgattg
    20461 atcattgtca aaaaagatac acaaacagat ctaagtcttt attctgtagt ggctgataca
    20521 ccagttggac caatcaaaat caaagacagt gcaatacttt acatggatga tccatccaca
    20581 cttgctttag aaccaactta taatagttta caattaaaag gaccaagcgg cttgagaaaa
    20641 ggcaacttgc aagttgttcg aaaagactag agggataaaa tgggaaaatt ggcgatcatc
    20701 agcgacctac atgtggacat caataaattc ggcgaatcag agctgatgca gctttggcaa
    20761 gttttgcaaa agcacaagat cactcggctt catctagccg gagatacggc taataaagta
    20821 gaccgttgcc tagctgttgt cgaatttttc gtcaataaag gattatctac gacatttcat
    20881 ttcggcaatc acgagttggc agatgtgccc aatgaacaga tgatggacca ttttccagac
    20941 ccacattttt taaatgaacg gtatattgct ttaaatgagc agaccgttct tttagggatg
    21001 aatggctggt acgactatca gttttccgaa ttgaaagatt acgaggcaat cgtacgaatg
    21061 aagcgtttgt attggtatga tcggttcatc cagcgtggga aaacagatct cgaggtcaat
    21121 gcagaaatgc ttgcagctgc aaaaaatttg ctagaccagc tggaagcaaa aaaacttgag
    21181 gtgattttat ccactcattt cgttcctaaa cgggcattta tcatgtatca atctgctcct
    21241 tatgagcgtt ggaacaaatt aaatgcattt ttaggatcag aatcattcgg agaattactt
    21301 gaccgttatt caaatatcaa acaagtagtt tttggccata cgcatcgtcg ctttgaagat
    21361 aaatccatcg gtcacacgat ttacagctgc agaccttttg gttattatta tgaatggcag
    21421 ctgacccgag attttgtctt gaaagaacag ttgctagaca gctatgatcc tatgaaatta
    21481 cgtgtcctct tgcgtgccca tcacccagct tttcaggcct atcaaacaca acatttgcaa
    21541 gaggaatttg aacaagcgat gacaatcgtt ccgtattgag acagcattag taatgtgtaa
    21601 aagaaaatac cttgtaaaac ataaggataa gtaagagcag tagatccatt tatcgtggat
    21661 atgctgcttt ttttgcggaa aataatcagc gaatgtttat ttgatcggat gatttgtaac
    21721 tcgcagagta ctagatgcaa gcgtgtattc tttttttgaa cgataatcac aaaaaaaaat
    21781 ataatataca ttttttattt aattataatt aatattgatt gaagtctagg cagtcaagtc
    21841 acattttgat agataggagg gggacttacg aattatttta aaggctatga cagctgtatt
    21901 tctagattgt gtttgcatca agttgcaata aaaactagaa atcaaatcgg gctgataatc
    21961 atttataact aatcgataca taggaccaaa tataggtcta tgttctttta tttcataagt
    22021 atcgtaaaac agaattttgc tatggattaa tccaatcgac tgatatgttt agtaaataaa
    22081 gaaagaggaa tgtcaatgat gaaaaaagaa atcgtattaa cagcagcaat gatgttattc
    22141 agcatggtag caagtacgac ttttgtttct gcaactgaag tatacccaaa ggaatataac
    22201 acagaaggaa cgattacatt tgaagcagga gatgagggtg taactcctcc tgttgatcca
    22261 gagaatcctg atcccaataa acctgtcgat ccatcagatc ctccaagccc tggaacagga
    22321 ggggcattat cgattgatta tggatcaaaa ttcaaatttg ggactcaaaa aatttctact
    22381 gcggataaaa cgtattatgc agctgctgat gtgatgaacg atgggtctag aaaaccgaca
    22441 tatgtccaag tgacagatag gagaagtacc ttatctgggt ggaaattaag tgtctctcaa
    22501 ccagaacagt ttaaaactgc cagtggggat gaactagttg gagcacagct gaaatttacg
    22561 aaagggcagg ctgtttcttt ggttgatcca acatatacgc cgcaaacggt gaattctgaa
    22621 ttaacgttga caccgggagg aaacaatacg ttagcaatta atgctaaatc aggaacaggt
    22681 gtggggactt gggtctatcg atttggtgca aatgaaaatg aaaatcaaga tgcggtacag
    22741 ctttcggtac ccggtaaatc tgtcaagtta gcgcaacaat attccactaa attagtttgg
    22801 acattagaag atacacctaa caactagttt actgaaaaga actgttaaaa ataaatacgt
    22861 agtcatattg tcttgcgagg taatcgagca aaaattgtca aaggctaggc taaatttgtt
    22921 tggatacgaa tagttcatct aggaatttaa cgatcaggag gaaaagatat attgaaaaag
    22981 aggaggatcg tgctcatttt aagcagtctc ttagtgacta atatctttcc gatcataggg
    23041 tactctttgg aattgaatca gttggagcat ggaaatagaa gagacgaaga aagcaaactc
    23101 acttcgacat tcgacagttt aatagaatcc aaccagacac aagaaagcag tgaggattta
    23161 agtatttcga gtagtggaga gaccactgac aacgtagaag ctgagggttc ggacaaacaa
    23221 ggactagaag atgcaccaat ttctgcggtt gagctgcctg acgatcccaa tattatttct
    23281 atcgataaaa tttttcaaac acctatcggt actagcacgt ccatattgga aaatgggaag
    23341 ttactgcagt tgaacccagc agaaaggtct caaagaggag ctatttggtc aaataagaag
    23401 attagtttac tctcggattt tacatttaaa tcttatttat acttaggaaa tcaacgagat
    23461 agagcgggag atggcatgac ctttacattg actggcgatc ctagaatggc tagtaatccc
    23521 agtcaagtta ttggatcgcc aggtatggga attggctcat attctactcg ttctggccaa
    23581 ccttacattg cgaatgcgct ctcgattgag tttgatacgt ataaaaatag tggttcttct
    23641 gatcgaatgg atcgagagat aactgctgat aatagagggc atggacatgt cgcttttgtc
    23701 acgcctaaac caaataataa taattattct ggagagcata ctggcgtgac ggtagctcct
    23761 acatttcttt ctaatggcac atggcgcttg ttaataatta aatgggacgc ggagcaaaga
    23821 agtcttactt atgatttgga aggtgtcggt cgctcttctc ggattatacc tgatctcatt
    23881 aggcagtttg gttctacaga agtaaattgg gggtttactt cttcaacagg tacttttttt
    23941 caagaaaatg ctgtcgctgt cacgcgactt ccatcgaatg tcacatcaac agctgatgta
    24001 aaagtcaacg atagtgatta tggggccatc gctgaagctg gaggaaacga taagataact
    24061 atcagaaata cattgaaggt cgagggggat tttcttgaat ataagaaaat gcagactagt
    24121 atcgacctcc cacaagaatt aactattccc gagcatatct tgatcaatgg aaatcaaatt
    24181 gatgccaaag atatcttgat aaccggaaat cgagtcacgc taaatctgac agattatttt
    24241 attgctggag atacgttaat aatcgaattg gagacaactt tgcaggaagt aattcctgaa
    24301 aaagtactca ctatgcattt tgaatacctt gaaaacggga atttgattga gcaatcgaat
    24361 gaaataaacc taaagatcgc aaagctgaag gagatagata tccatgttta ttataaagat
    24421 aaagacagtc agattgatat tgctgaaatg aaaacaatca ctgggaaaat aggagagaag
    24481 tataaagaaa ctcctattga tattgaaggg tatgtttttg actcggattc agcgaataca
    24541 gaaggcatct tctccgaaaa tacagaggat atctattttt attacagaaa aggcaaactt
    24601 tatctctcaa ctgctcctca atatgtcaat tttggaaaac ataaaatatc cagtagacca
    24661 ttaagtgaat tcggacagtt ttcaggtggg ttgaaaatta tagatgaacg ggcttttgga
    24721 agttggaaat tacaattgaa acaagagaaa gttcttacaa atggagattt tgagcttcca
    24781 gaagctcttt cctttgttac ctctgaaaat acaacggtta tagggacatc cgctgttacg
    24841 attttcgaaa gtgatcaaaa gggtgaaagc gatttgtcct ctcttttaga ttctacagct
    24901 catcgtggaa tcagaataga tattcctgta gaaaaccaaa gaatcggaac ctttgagggg
    24961 aaactatctt ggatacttgc agatgtccca ggaaattaac aggaagagaa gaatataaca
    25021 aaattattga gtttcaagaa gggcacaggt accataggct cttgtgtccc acagagacaa
    25081 gattttgtta tagtcttctc ttacatatga ttaaaggagc gattttcttg agaccaaaac
    25141 aacaattatt tataacactc ctagttattt taggggcact ttttaacaat atatcagtgt
    25201 cagctagtgc atttaatttt tcagtgacgc cgataacttc agagaatcaa atcgacaaga
    25261 gaaaaactta cttcgatctt caacttgatc cggatcagga agtagaagta aaagcggaat
    25321 tgagaaatga tacagaaaaa gaagtgaaaa tcgatatttc tgtgaatagc gcaaccacca
    25381 attcaaatgt gatggttgaa tacggaaaaa acgagattga aaaagacatg agcctgatct
    25441 ttgatctggt agattatgtg agctatccac agatagtgac gctaaaacct aaaagtgtcc
    25501 aaaccgttgc ttttcatgtc aggatgccga atgagcgatt tgatggtgta ttggctggtg
    25561 ggatcacatt ccaagaaatc cagacggaaa aggaccaaac agaaactaag gatcaaagct
    25621 tatcgattga gaatgaatac acctatatta ttgctttgtt gatgcaacag acactgaacg
    25681 aagttgctcc gaaccttact cttcatgaag ttaaaccaga tcaaatcaat gcaagaaatg
    25741 tcatcttagc aaacgttcaa aatgatcaaa aaacctatat caatcaagta gttattgaaa
    25801 caaaaattac aaaaaaagga cattctgaag ttttatatca agaggaaaaa gaaggattgc
    25861 agattgcgcc gaatacaaat ttttcttttc caactgcttt aaatggtcaa ccgctaaccc
    25921 caggtgaata tcaccttaca atgactgttt taggaaatga aaatgaaaat ggaaaatttt
    25981 cgagaaaaaa aggaaatact acgatcaact ataccaatca atgggtattt gaaaaagatt
    26041 ttacaataga cggaaaagta gccaaggaat tgaacacgac ggatgttacg attaaaaaag
    26101 acaataattg gatttatatc ttagtagctt cacttttctt attgtttatt ttattatgca
    26161 tacttttgtt tgttttgaga aaaaaagaag agaaagaaaa gtaaggttaa gataacaaat
    26221 agtaaatttt tattattgta ggatggttgg gctcttttta taacaatata aaatatacca
    26281 ttttattaat aaaaatgcat actagtaaat gatataattc taataacagg tttgatcgcg
    26341 agaaaggcca aataaaacgc tctccaaaat gttaaaaaaa agacaggacg atgtatatta
    26401 tacaaacaag aatcgctgac aacagtgact cggatccagg aaatcagttt tatccccagc
    26461 tagttggtga atgcatggaa agtaatatac gtagaaagag ctgatgacta atgaattatg
    26521 agtttttttt aagcaaagaa gatcacagaa gttattcatt acttaaatat ttagaagcaa
    26581 gctcaaattt atcagagtca atatcgaatg ttcaagaaga gttgtcgcta tcgacatttc
    26641 tcttgaaaaa aacgatcgat aagctgaaac atgatttaca aaagttcgat ctagagaaaa
    26701 atttgcgagt aaccgtcagt gaattggata tatgtctgga aattaatgga aaatgttcta
    26761 gcaaagctct gttatctcgt tatataacgg attctttatc tatgaaaatg gtattggctt
    26821 tctttcagga aaaatatatc tcagtagaaa attttgctaa acagcatcac gtgagttatt
    26881 ctgtggctta taaagtatta caaagactaa aaagaaatct aaaaaaatat caaatttttt
    26941 ttgaaaagag aaagttg
//
LOCUS       DARPZF010000033        26902 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.034, whole genome shotgun sequence.
ACCESSION   DARPZF010000033 DARPZF010000000
VERSION     DARPZF010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26902
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.034"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(40..1146)
                     /locus_tag="SLE65_001780"
     CDS             complement(40..1146)
                     /locus_tag="SLE65_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEI8449074.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRTRYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            1356..2357
                     /gene="ccpA"
                     /locus_tag="SLE65_001781"
     CDS             1356..2357
                     /gene="ccpA"
                     /locus_tag="SLE65_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEI8449075.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLADRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEGFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(2694..5039)
                     /locus_tag="SLE65_001782"
     CDS             complement(2694..5039)
                     /locus_tag="SLE65_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEI8449076.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            5318..6220
                     /locus_tag="SLE65_001783"
     CDS             5318..6220
                     /locus_tag="SLE65_001783"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HEI8449077.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            6433..8208
                     /locus_tag="SLE65_001784"
     CDS             6433..8208
                     /locus_tag="SLE65_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HEI8449078.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(8274..9860)
                     /locus_tag="SLE65_001785"
     CDS             complement(8274..9860)
                     /locus_tag="SLE65_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HEI8449079.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQEMVEEIE"
     gene            10111..10335
                     /locus_tag="SLE65_001786"
     CDS             10111..10335
                     /locus_tag="SLE65_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEI8449080.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            10476..12227
                     /locus_tag="SLE65_001787"
     CDS             10476..12227
                     /locus_tag="SLE65_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8449081.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSVKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIISAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            12227..14011
                     /locus_tag="SLE65_001788"
     CDS             12227..14011
                     /locus_tag="SLE65_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8449082.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            14337..15188
                     /locus_tag="SLE65_001789"
     CDS             14337..15188
                     /locus_tag="SLE65_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEI8449083.1"
                     /translation="MLIEKVLNNNVVITRDERDREMIVMGKGLAFKKKVGDPILDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVHLNDSVYISLTDHLY
                     TAIERQKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GAKSEDGEVSEELFQVVQKKYKDTFGCVEKIADFLTGAFDYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            15285..17165
                     /locus_tag="SLE65_001790"
     CDS             15285..17165
                     /locus_tag="SLE65_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEI8449084.1"
                     /translation="MGKYQELAENIVKNIGGKENIRSLTHCVTRLRFKLKEENKAKDD
                     VLKKMEGIVTIMKSGGQYQVVIGNHVPDVYAEVLTVAGISDEVEEEVSSSSNLFNRLI
                     DILSGCFQPFLGALAAAGMVKGLNALFLFLKFYTEGSGTYIMLNGIGDAIFYFMPVIL
                     GYTAAKKFHLNPMVGLVIGAALCYPTVQGAALQSGFPDGSPAPYSLLGLPAYETFLGI
                     PWVGSSYTSSVVPVIFIIAFAGQVQKIAKKWIPAVVQTFLVPFSVLLIALPAGFLIIG
                     PIVSILTDLLSTGFQALMDFSPAVYGAVLGFLWQVLVIFGLHWSIIPLAIMQLAQNGW
                     SQMLVGVYGASFAQTAVVLAMYFKFKDQKMKALCMPAVISGIFGVTEPAIYGITLPKK
                     KPFIYSMIGGAISGIYLMASGTISYTMGGLGIFGVVNYITETDASGMFQAFIGIAIAS
                     VIGFSLTFFFWKDEAGETDAIQKKSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGRGI
                     LIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESLVQ
                     QGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGETVGPDDALITA
                     LT"
     gene            complement(17205..18107)
                     /locus_tag="SLE65_001791"
     CDS             complement(17205..18107)
                     /locus_tag="SLE65_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEI8449085.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKYLLLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENKVILRTAEILKQNHVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            18338..19741
                     /locus_tag="SLE65_001792"
     CDS             18338..19741
                     /locus_tag="SLE65_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEI8449086.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALNDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            19741..21174
                     /locus_tag="SLE65_001793"
     CDS             19741..21174
                     /locus_tag="SLE65_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEI8449087.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDVFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQVKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            21319..22245
                     /gene="trxB"
                     /locus_tag="SLE65_001794"
     CDS             21319..22245
                     /gene="trxB"
                     /locus_tag="SLE65_001794"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEI8449088.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            22459..24186
                     /locus_tag="SLE65_001795"
     CDS             22459..24186
                     /locus_tag="SLE65_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEI8449089.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEEAKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            24201..24551
                     /locus_tag="SLE65_001796"
     CDS             24201..24551
                     /locus_tag="SLE65_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEI8449090.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(24643..25503)
                     /locus_tag="SLE65_001797"
     CDS             complement(24643..25503)
                     /locus_tag="SLE65_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HEI8449091.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLKQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            25595..26023
                     /locus_tag="SLE65_001798"
     CDS             25595..26023
                     /locus_tag="SLE65_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HEI8449092.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            26185..26361
                     /locus_tag="SLE65_001799"
     CDS             26185..26361
                     /locus_tag="SLE65_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEI8449093.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            26388..26834
                     /locus_tag="SLE65_001800"
     CDS             26388..26834
                     /locus_tag="SLE65_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HEI8449094.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT         8514 a         4797 c         5747 g         7844 t
ORIGIN      
        1 aaaaaggtgg gagcggacta gctctcacct tttttactct tatttttcta aaacaagtaa
       61 ttcttttggt gtagtcgtga atggcacaca gccatcgctt gtcacatata cacagtcttc
      121 gatacgtacc cctacttttt caggaatata gattcctggt tcaagagaga agcacatccc
      181 ttcttcgatt actaagtcat ttccttctac aagggaaggg aattcgtgga cggttgttcc
      241 gatcccgtga cctaaacggt gattgaaata ttcgccgtag ccatagctgt tgatcacgtt
      301 tcgtgcgatt tgatcaagtt cacctgctgt cacacctgga cggacggctt cttgtgcggc
      361 aagctgtgct tcaagagtga tgttgtagat tttttcttgg aagtcggttg gtttttgata
      421 agcaattgta cgagtagcat cactgcaata gccattccaa acaacgccaa gatcgaataa
      481 cacaagttca ttcggtgaaa tcttcgtatt tcctggtgta ccatgagggc ttgcagcatt
      541 tgctcctgca aggactaatg tgtcgaaaga catttgtgaa acaccttgtt ttttcaattg
      601 gtattcaatt tctgcaatga tcgcttgttc agtcacgcct tctttcactg ctttaaagcc
      661 aatctcaaat gcaacatcgg cccatttacc agcttcgatc agtttgtctt tttcctctag
      721 agttttgatc agttgtagac gttggatgat ggaagttaga tcagtgtaag aatccgttcc
      781 cgtcaagata tcagagatag catcgaagcg ctcgacagtc aaggcgttct tttcaatccc
      841 tacattgcca ggctgaccat agcgagtacg aagttctttt ccgatgatct cccaagggtt
      901 ttcgctgtct aaatagccgc ggacatcata cgcccaacta ctgttttgag catcttcaac
      961 ttccaaagca ggagtgaaaa ggaaaggatc ttgttcaaga gggataaaaa gagctagtac
     1021 acgctcatga ggatcacttt cgtatccgga aaagtaagcg atgtggccag ggtcgctgat
     1081 ataagccaat tcgacttggt gttgtgccat ccattgacgt agttcattga tttttacgtt
     1141 attcatttgg caacctactt tctaaattaa ttttgtattc aataattgta ccactgattt
     1201 attaaaagac caacgttcta aaaactgaaa aaagtaaaaa ttttcatgaa aacagagata
     1261 aaacggttgc aattcttgag attatttgat attctatttt agaaatgtaa gacgtatttt
     1321 cagaaaacat ataaaatatg aatgggagaa cacaaatgga aaagcaaaca atcactatct
     1381 atgatgtagc gagagaggca aatgtttcga tggctactgt ttcacgtgtc gtaaatggca
     1441 atccaaacgt taaaccagca acaagaaaaa aagtcttgga agtcatcgat cgcttggatt
     1501 atcgtccaaa cgcagttgcg cgtggcttgg caagtaagaa aacaacaaca gttggggtaa
     1561 tcatccctga tgtcagcaat atgttctttg cttctttagc acgtggtatc gatgatgtgg
     1621 caacaatgta caaatacaat attatcttag caaattcaga tggcaacgac caaaaagaag
     1681 tcaatgtatt gaataactta ctggctaagc aagtggacgg cgtgatcttc atgggtcacc
     1741 atatcacaga cgaaatccgt ggagaatttt cacgttcaaa aactcctgtt gtattagctg
     1801 gctctattga tccagatgaa caagtaggta gcgtaaacat tgattatgta tccgcaacaa
     1861 aagatgcagt aaataaattg gcaaaaagcg gcaataaaaa aatcgctttt gtcagtggtg
     1921 cgttgatcga tcctatcaat ggacaaaatc gtctgaaagg ctataaagaa gcattaagcg
     1981 aaaataacct accatatagc gaaggattga tctttgaagc acaatacaac ttcaaagatg
     2041 gtctatctct agccgatcgg atccataata gcggtgcaac agctgtctat gtttcagatg
     2101 atgaattagc catcggtatt ttggatggtt tattagatcg tggcgtgaaa gtaccggaag
     2161 gattcgaaat catcacaagt aacaattcac tactgacaga agtagctcgt cctcgtttaa
     2221 caagtatcac acaaccatta tacgatttag gggcggtatc tatgcgccta ttgacgaaaa
     2281 tgatgaataa agaagaagtc gaagaaaaaa cgattatctt gccttatgga atcgaagaaa
     2341 aaggatctac aaaataataa aaggacaacc attcagaggt tgtgagcctg ccgtttaact
     2401 ctgcgttaca aggagcaatt tcaaaaaaca gcatttcatg tttgatgaat attgtgactc
     2461 gtgattcgga gttggcagga gaacaccgtt tattcgggaa aaggggttat gacaaaattt
     2521 tgttataatc ctttttttgt gtcttaaaaa agagagaaag tggttgaaat tacatttatc
     2581 gtatataaaa caatccgtgt atagatgctg cattttgttc accaccatca aaaaaataag
     2641 ggactgtgac aatactattg tcacaatctc ttattactgt gtattctatt aaatcaatca
     2701 tctttctcat ctgattcttt ggttgcttga ttcgctcttg cataagctga agcggtgttc
     2761 cagtaatctg tatagttttc atcggtaccg ccaacgccaa atttaaaggc gcttttcttc
     2821 ggtccatttt tcgcccatag cgattcaact gtttttccag gtgtttggat ggatttttta
     2881 ttgacagtaa cttttccagg tgtttgacca gtaaatccag atactttttt cttcatcaca
     2941 tcagatgata attcgaattt ctcatcagtg ccaaaaatgt caggttttgc ttggtaagct
     3001 tgattgatca gattggcaag ataattagcc gaacgtatcc ttgctttgct gtccattcca
     3061 gtattgtcat cgtgccctgc ccagctactg atggtaatag acggagtaga gacaattagc
     3121 catgaatctc ggtattcatt ggtagaacca gtttttccga cccaatctgc ttttcctaga
     3181 tttccgttta agcttgagat ggcatctttg aatggtgtag tgatttttgc attgatcaca
     3241 ctgcgcatca tgtcattcat gatcgatgcc gttgcttccg aatagatccg gacagagttg
     3301 ctttcgtgtt tataaattac atttcctgcg ttatctgtga tggaatcgat gatatagcct
     3361 tcttcataga cgccgccgtt tgctaaagcc tgaaatccat tggtctgttg aagcgtcgtg
     3421 acatctactg tacctaaagg agcagattca acgccccaat tgtcatttgc cgggtagttc
     3481 atctttgcca agtagtgctc gtaagcatat tgtttcgatc caccggaatt caacacatct
     3541 tgatataagt gataagccgg gatattgttg gaccattcta gtgactcacg gacggtttgg
     3601 aaggtgttcg atccttcgtt agtagcattg acgattttct cgccagcatt ttctccttct
     3661 tgccaagttg ttgcataatc tgatacacgg gattctgatc cgataagccc catgtcgatt
     3721 gcaggtccat aaacaagaac tggtttgatt gatgagccag cttgacgttc tgtatcgaag
     3781 gcatggttat tttgattctg actgtaattc cgtccgccaa cgaatccgta gatgcggcca
     3841 gttctgttat ccatcaatac atttccggtt tctacttgac tgccagcacc atcatctaac
     3901 atgtatccat aattttctac gccattttgc aatgcagcat agacatcttt atcgattgtc
     3961 gaatggattg tatatccttt attttggatt gtttgctgtg ccttttgata ataagcgtca
     4021 ctgaccgatg aatcagacat atcagcgttg tctttttcag ccaattgttg tgcaatgatt
     4081 cttgttgctt cattcatcac agtataatac aagaattctc tgtcagtctg ttctgcgatt
     4141 tgttgtggta gaaagtcttt tgtaaggtca taggcttttg cttcttcgta ttgttctttc
     4201 gtaatttggc cttcacgata catactgaat aaaacaaaat cttttctggc aaggccggca
     4261 gaaagatctt cttttagcgc acctgtgttc gtgtatggac tatacgtgat cgggctttgg
     4321 ggtaatccag cgatataagc agcttgcggc agcgtcacat cttttgcatc tacaccaaag
     4381 attcctcttg cagcttcctg gactccagca atgttttgtc ccttattatt acgaccaaat
     4441 ggtgagacat tcaaatacgt agcaatgatc tcatcttttg aaaagtattt ttctacttgt
     4501 gcagaaagaa tgatctcgtt tgctttacgt ttgaatgttg tttcatctgt aaggatctgc
     4561 tgtttgacta attgctgtgt caaagttgat ccaccagaag agccaatacc agtagcttca
     4621 gatactaacg ctcgtaaaac agctttagga acgtaacctt ggtgtttatc gaagtattca
     4681 tcctctgtgc tgataattgc agttttcaat aaaggtgaaa ttttatcaga tgaaatagtc
     4741 gtgcgcatca gatctgtctg gatttttgat atctctgtat tatctgcata aacaatcttt
     4801 gacgtttctg taatgtttcc tagttctgtc tgcagtgctt ttttagtcgg caattgtgtg
     4861 tcttcgacga gataggcaaa atagccagcg cctattccaa tacctagagc tgcgaacatc
     4921 aaaagaagaa cagtaataaa aacagtcaat gattgaaaaa ctctaaaaat aatcttagga
     4981 acaaaccatt tttctttttt tcttctattc tgtttttttc gagtattttt gcgtggcaaa
     5041 agggtcacct caactaatgg ttttatttcg ctaattatag caaataatag aacaaaaaaa
     5101 cagacaaggc tgtttttggc aggaatttct tttttaaagg agttaaaacg tgagaaaatg
     5161 atctttttta taaaagagtt cttaagcttt tctttagaga aaatttcagt tactatggag
     5221 aacagggcaa agaaaaatca atcattttct ttgtatatca tcttaccaat atataggaat
     5281 tgttagtaac aattgccttt caaggaggaa tccatccatg ttattaggct cacacgtcag
     5341 catgagcgga aagaaaatgc tgttaggagc agcagaagaa gcagccagtt atggatcttc
     5401 gacttttatg atctatacag gcgcccctca aaacactaga agaaaagcca tcgaagagat
     5461 gaatattgat gccggaaaag cgtacatggc agaaaacggt ctaacaaata tcgtcgttca
     5521 tgccccttat atcattaatt tggggaatac gatcaaacca gaaatgtttc cttttgccgt
     5581 ccaatttctg agagaagaga ttgttcgtgc ggaagcttta ggcgctactc aaattacact
     5641 tcacccaggt gctcatgtag gggcaggaac agaagccgga attgctagaa ttattgaagg
     5701 cttgaatgaa gttttgacaa aagaacagac ggcacaaatc gctttggaga caatggcagg
     5761 taaaggtacg gaaatcggtc gaacatttga ggaattagcg caaatcatcg atggagtaaa
     5821 attgaatgaa aaattatccg ttacttttga cacctgtcat acgaatgatg ccggttataa
     5881 tattaaagaa gacttttcag gtgtaatgga agagtttgat aagatcatcg ggttagatcg
     5941 gcttaaagta ctccatatca atgattctaa aaatccgcaa ggttcgcata aagaccgaca
     6001 cgccaatatt ggttttggaa caatcggatt cgacacgctg aataagatcg tccatgatcc
     6061 aatgtttgac aatatttcga aaatcttgga aactccctat gtcggcaaag ataaaaagaa
     6121 agcttacgca ccatatggaa aagaaatcgc catgttcaaa gcacaaatat tcgatccaga
     6181 agtgtttcct gagttattag cagaagaagt gatactctaa gattttctat ctgacagcag
     6241 caaaaaagga ccaggcacat tgccttgtcc ttttttgttt aagaaacaaa ggagtgcttt
     6301 ttgcagtctt tttcatcatg catcttctcc cccctctttt taaatttaga caaacagggt
     6361 atactggtag aaaagtaaaa aaacgaaaag tttcacaagc aagtggcaaa acgtgattgg
     6421 aaggacgaaa agatgctgaa cactttaaaa cccttgatca accaactaaa aaagaaacat
     6481 acatacttta ttcttggcat agccctatta tttacaatta ttcgtttgta tttatatagt
     6541 aaagcaatct atggaacaga catgtcggca acctatgatg accagctgct gattcgctat
     6601 gctcaaaata ttttggacgg taaatggcta ggggagtata cgactacaac actttccaaa
     6661 ggaatctcct acagcttatt tttagtactt gcacataaac tgcatctttc ttatgcagtt
     6721 ttgttcggca tgttcagtat ttttgccagt atattggttg cactcgcgtt taaaccgatc
     6781 gtgaagaaca agtatcttct tttaagtttc tatttttatt ttttgttttc tccgattagt
     6841 tttacacatg aatattccac tcgaacgtat cgtaatgccc tcgtgattcc ggctgttgag
     6901 atcattatcg cttgtttact agctatttat taccgcaaat acggttctag cagaaaattg
     6961 ctgccatggt ttttagggct ttctgtcgct tttcctttct tttggttcat tcgcgaagat
     7021 tctatctggc ttcttccttt tactgtagta gctttgggta tcagtttcgt ccagatcttg
     7081 ctagggcaag acttttcttt caaagaagta aagaagttaa aaaaacgact ctttcttctc
     7141 tcgaaacggg aatggctgaa actttcattg tttttacttc ctatagttgg cttttccatc
     7201 gtctatcagt ggatcgaata taaaaatgag acaacatacg gtattgcaac catcaatgac
     7261 cgttccagtg gagaatttgg acgtttgatg aaacaactga tccgaataga tgatgaaacg
     7321 aacttgaata aagaaaacag tgagatatgg gtctcacatg ctgcactaaa taaagcatta
     7381 gccgcatctc ctacattcca tactgtttct acccgtattg acgaattata tacgactcac
     7441 gcgtggactc aaggtggaaa agtaaaagaa ttacccggag atatcatctt ttgggcattg
     7501 cgagatgtgg taagcgaatc tggttattac caaaacaatg caaaagaaac caatgatttt
     7561 tggaaaaaag tcaaccaaga attagaagaa gcctatcaca agggaaccat caaaaagaaa
     7621 aaagagttct atctgatggg atcaggagat ggaaagacga tgagtgatct accaatcgta
     7681 ttcgatttcc ttcaatcagg atacgcttat gcatggcgat ataaagattt ccatcaagga
     7741 ggaaattata gtttcggaac gcaagaacaa gtcaaacagg ctcaagaatt attaaacctt
     7801 ccgctaatgg agaattggat cgatagtaat gaaccgagaa cacctaattt ccaattaaca
     7861 aaatcagcaa aagtcgcgaa tgtcatcata aaaatttacc aagttctggc tattcccgtg
     7921 ctgattgctt caatagcagg gatattactt atgatactag gaaccgtatt tgcaaaagct
     7981 gatcgtgcct attatagttc ctctttgatt gtggtcaccg gattaatact gacacaattg
     8041 gtttttcttt tcggtgtctc gtggttttgt tcttatgcgc cagaaaaaaa ggattatttt
     8101 ttaagtgtct acactggcgc aggcgtgccg ttaacgcaat tcatcgtagt aacaagcatg
     8161 ctagttttca gtaaattaaa tctgaaaaaa gctttatctt ctaaataaaa agacccttgg
     8221 tagctagatt tttaacctaa ctatcaaggg tctttgtgtg gaaaaatcag tttttattcg
     8281 atttcttcta ccatttcctg caaacgctgt tcatattttt tgtttccttt atataaatca
     8341 ccaatcgtcc atgccaacag gaggaggaca agaacaatga ttacataagc gatgtgatca
     8401 gccaatgcta gttgagcgga agtggcttgc tcgccgaaga aactttcgat ctgtcctggt
     8461 aatcctcgta agttcaagta agttagacta atcacagaga accagccaag aagttttacg
     8521 atgaatgaat ttttaaatcg gctacccatc tccgcttggc tgttggtcat catcagtaaa
     8581 gggatcatcg aaaacggcaa cgcaaaagcc aagaacacct gggattcatt cattaagtta
     8641 ttcaaagcgg tatgttcttc gatcgttcct tttgtacttg taaacaaaac acaaatcaat
     8701 acaggaatca cagaaagcaa tcgtgtgacc agtcttctta gccaaatcgg gatacgcata
     8761 tggatgaatc cttccatgat gacttgaccg gtcaacgtac cagtaatagt agagttctgg
     8821 ccagaagcaa gaagtgctac agcaaataaa gtggacaaga taccagattt tgctacagca
     8881 atcaagatac cattgctcat agctgatgga tcagataaag cttcatacag accaaaaaag
     8941 gaaggatctt gaacagaacc ggttttgaag acagcgacac ccataatcaa tagcagcgca
     9001 ttgactagaa aagccatcga caattggata ttagagtccc aagtagaaaa acgtacagct
     9061 tgtgctacat cttcttcgtc ttggtgatcg atcttccgag tttgtgaaac tgctgaatgt
     9121 agatataagt tatgtggcat gactgttgcg ccaataatcc ctaatgctcc agttagcgga
     9181 gtttcgccac caatgacagg tgagtcggag aatgtatggc tgttagggat aaagccagca
     9241 aataaactgt gccaatctgg gttagacaag ccaacttgat agacaaaaac gaataaaatg
     9301 acgaaaatca agcagacaac cagtgcttcg atcttacgaa acccgacttt tgtcagtagt
     9361 aagagaacga aaacatctaa tacagtaata aagacggcaa tcaccaatgg aatatcaaaa
     9421 agtaagtaga gggcgattgc tgcaccaatg acttctgcaa tatctgttgc cataatggct
     9481 aattcagtca agatccataa aatgacaccc aatgtcttac ttgtgcgtgc tcggattgct
     9541 tgggccaaat ccatttgggt cacgattcct aattttgctg ccatatactg taaaagcata
     9601 gcaatcagac tagacatcaa aataactgac atcaataaat attggaaatt ttgtcctccg
     9661 gtgatcgaag tagaccagtt acccgggtcc atatacccaa ctgctactaa cgcaccaggt
     9721 ccagagtaag caagaagtgt tttaaaaaaa cttttcccct ttggtacatc cactgttcca
     9781 tttacttcag ctaaagataa accatttgta tgttcaataa gtcgatgctt atgaaattgt
     9841 ttgttggatt gattattcaa gaaaaaacca cctttcctat ttatctacga ttacattcta
     9901 cacctcaaaa agaaaaaatt aaagaaaaag attcggtatg cctaattttt tttcgtggcg
     9961 tgtcttgcta gatgacgaaa gaaattttgt tctcctctaa aaaaaccact attttttgca
    10021 tgaaactaaa gaatacgcct ttcttttttc aataaacttt agtaaaataa gtcattgaga
    10081 gcaattcgga aatagaaagg agagatttat atgttatcaa caggtattgt cgtacttatt
    10141 gctattattg ctttgctaat cggcgcagta ggtggctttt tcctagcgcg taaatatatg
    10201 aaagactatt tagaaaaaaa tcctcccgtt aatgaggaca tgttgcgatc aatgatgatg
    10261 tcaatggggc aaaaaccatc tgagaagaaa attcgccaga tgatgcagca aatgaagaac
    10321 caagggaaaa aataggttct gacccaacga ctttttacgg gctgattttt tcagtccgtt
    10381 ttttatttcg taatttgtta gactattcag attattcagc aaaaagacaa gcacagacaa
    10441 tcctaggctc ttgataaaga caaaggagga gtaaaatgtc gatttttaga aagttaggct
    10501 ggttttttcg tcaggaaaag aaacattatt taattggggt tttctcgcta ttcgcagtgg
    10561 ccttggtaca gttagttcct ccaaaagtga ttgggatcat cattgatgag attgccgata
    10621 aaaatttatc agtaaagatc attttcgggt ggatcttcct attgattatc gctgcttttt
    10681 tacaatatct ttttcgttat atctggcgga cgaatatttg gggaagtgca gctcggttgg
    10741 agaaagaact tcggcagcag ttattcaaac attttacaga aatggacaat ctcttttacc
    10801 aaaaatatcg gactggggat ttgatggctc atgcaacgaa tgatttgaat gcgatccaga
    10861 atgtagcagg agctggtatc ttgacctttg cagattcagt gattacgggc ggaacaacga
    10921 tcattgcgat gattttgttt attgattggc gcttaacact gattgcgctg attcctctgc
    10981 ctttgctggc cgtcacttca cgagtgctgg ggtcgaaact ccatgatgct tttcgtgatt
    11041 cgcaagaagc tttttctagt atcaatgata agacacaaga aagtatcact gggatcaaag
    11101 tcattaaaac atttggacaa gaaaaagaag atctagcgga ttttgaagaa aagattgaag
    11161 atgcaattat taaaaacaaa cgagtcaatt ttttagactc cttatttgat ccattcatta
    11221 ccttgattat cggtctgtct tatgttgcaa caattatttt aggtggaaag tatgtcttgg
    11281 aaggcacgat ctcgatcggg cagatggtct catttattag ttatatcggt atgcttgttt
    11341 ggccgatgtt tgcgattggt cgattgttca acgtattgga aagaggaaat gcttcttatg
    11401 atcgcgtcaa tgaacttttg catgaaaaaa cgcatatcgt ggaacaactg ggtgcagtgc
    11461 agaccccggc aaaaggcgag ctgaatgtag ctatttcctc ttttaattat ccgaaagaag
    11521 aatcaccagc attagaacaa atcaagtttg caatccaaga aggagaaaca ttaggtattg
    11581 ttgggaaaac tggtgcggga aaaacgacga tcatcaaatt actgatgcgt gaatacgatg
    11641 attatcaagg gaaaatccaa tttggcggac gttcgatcaa agaatattca ttgaatgctt
    11701 tattaggatc aatcggctat gtgcctcagg atcacttctt gttttcgatg accattcgag
    11761 ataatatccg tttttctaat ccaaaacttt cagaagaaga agtagagcat gcggcttctt
    11821 tagcatttat caacaatgaa atcaaggaat taccaaaagg ttatgatacc ttagttggag
    11881 aacgtggagt ctctttatct ggcggacaga aacaaaggat ttcgattgct cgagcattga
    11941 tcaaaaatcc tgaattatta atattagatg atgcactttc tgcagtagat gccaaaacag
    12001 aagaagctat cttgcataat ttaaaagaaa taagaaaaga gaaaacaact atcatttcag
    12061 ctcaccgttt aagtagcgtg atgcatgcaa aagaaatcat tgttgtcgat caagggaaaa
    12121 tcattgaacg aggaacccat catgagctgc ttgcactagg cggctggtat gaacaaatgt
    12181 gggagaaaca gcaattagaa gcgaagatag aaggaggcga ggcctgatgg atgaaaatta
    12241 tcaatcggaa tggacaaaat cgattccact taaagaacag aaaaagatca tcaaacgact
    12301 gatgaagttc gccaaacctt ttagaagaac gttcatcgtt gctatcttat ttgcgtttgc
    12361 tctgtctgtg atcaatgtcc tattgccaag gatcatccaa acttttatgg atgatcatct
    12421 ggctaaacag tcggctacga cacaagttat tttgtttttt gctggtatgt acttatttgg
    12481 agtcatagta aaaagtatca tttggttttt ccaatggtat ttgtattcca tggcttcatt
    12541 gaagacctat cagtatatta gggtaaaatt atttgaaaag ctgcatacac taggtatgcg
    12601 ttattttgat cagacaccgg caggatcaac cgtttctcga gtgacgaatg acacagaaac
    12661 gctatttgaa ttttggtacg tctttttgat ggtattgact gggatctttg cagtcgtttc
    12721 ttcattcatt gccatgtttc aaatcaatgg agaaattgcc ttgtggactt tggtgttctt
    12781 gccaatttta ggaatagtca tctggtatta ccagaaattt agttctcgta tttaccggaa
    12841 tatgcgggaa aaattaagtc agctgaatac gaaattgaat gaatcgattt ccggcatgcg
    12901 tattatccag cagtttcgcc aagaagctcg tttagctaaa gaatttgaac aagtgaacaa
    12961 tgagtattta gacacgcgtt atgcgatgat caaaacaaat tcgattctgt taagtccgat
    13021 catcaatttt ctatatgcat tggcgattgc gttggtgttg actttgtttg ggatcgatgc
    13081 gttgcattct cccgtagaag ttggactgat ctatgcattt acgacctatg tccagggatt
    13141 ttttaatcca atgtctcaaa tgatggactt tttgagcatc ttcacagatg ggatggttgc
    13201 tggtagtcgt atcttgaaga ttatggatac agaagaatat gcaccacaac aaaaccctgg
    13261 agcagatcaa atgattactt caggtaagat tgagtttcgc aatgtaagct tttcttatga
    13321 tggagagcac aatgtattaa acaatatctc ttttgttgct aatccgggag agaccgttgc
    13381 attagtggga cacaccggaa gtgggaaaag ctcgatcatc aatgtgttga tgcggtttta
    13441 cgaattttat gaaggtcaga tattgattga tgatcatgac attcgagaat atccaatgga
    13501 agagttacgt aagaaaatgg ggctggtctt gcaagatgct ttcttgtttt atggggatat
    13561 cgcaggaaat attcggatga tgaatccagc tatcacagac gaacagatac gccatgcggc
    13621 tgagtttgtt caagcaaaca aattcatcga tgaattacca aaaggatatc actcaaaagt
    13681 gatcgaacat ggtgccagct attctagtgg acaacgacag ctgatcactt ttgcgcgaac
    13741 aatcgtgact gatcctaaaa ttctagtatt ggatgaagca acagcaaata tcgatactga
    13801 aacagaagga ttgatccaag aaggattggc gaaaatgcga caaggacgga caacgattgc
    13861 gattgcccat cggctgtcaa cgattcgaga tgcagaattg attttagttt tagacaaagg
    13921 tcatatagta gaacgcggga atcatgaaac acttctagcg caaaatggtt tgtatgcaga
    13981 tatgtacaaa ctgcaaagca gtggtatata aaagatgttg tgacagtagc attttgacct
    14041 aagcactaga gtgaaaataa aacatagctt cccatatttt tcatctgtga gagttagtgt
    14101 cgtagttacc agatttaaaa aagacgacgt cagctagtca gaagtgccta atagccccta
    14161 agaaagcgtt gacaaaatcg tttgctttcg ataatataaa gaaaacgata caacttggat
    14221 agtgattgcc tgatgcaagc taaacctaat gagtctccca tggtttcatg gacggctttt
    14281 tgggtttttc tttttgtttt ggatacagcc ctatatatca tggaaaggag caaaacatgc
    14341 tgattgagaa agtactgaat aacaacgtcg taataacaag ggatgaaaga gatcgggaaa
    14401 tgattgtgat gggaaaagga ttggcattca aaaagaaggt gggtgacccg attcttgatt
    14461 catgcatcga caaaaaattt cagttgacaa atgacggact ttcacaacag ttccaagaat
    14521 tggcacaagc gattcctctt gagtacttag aaatttcttg tgaaatcatt gaatatacaa
    14581 aagaggctct gcaagtccat ttaaatgatt ctgtgtatat ttcattgacg gatcacttgt
    14641 atacagctat cgaacgtcaa aaaatgggga tctttgtgcc aaatgtattg ctgtatgata
    14701 tcaaacaact gtttcctaaa gagtatgcca ttgggaaaaa aacagtgaag aaaatctcgg
    14761 ataaatacca catcaagtta tcagaagacg aagccggatt tatcgcattg catttagtca
    14821 atgcacaagg cattcaaagc cagcaagaca atacctacct gtttaccaca acaatacagg
    14881 atattttaaa tatcgtccgc tattactata agattacatt tgatgaagat tcagtccact
    14941 tttttcgatt cgtcacacac ctgcgttttt ttctgacacg tgttctagat ggagcgaaat
    15001 cagaagatgg agaagtttct gaggaattgt tccaagttgt tcaaaaaaaa tataaggata
    15061 cgtttggttg cgttgagaaa atagcagact ttttaaccgg ggctttcgac taccagatgt
    15121 ccacggatga aaaaatgtat ttaacgatcc atactgcgcg tttagtgcat gagaatcgtt
    15181 gtaaataaat aaaaaaggag gacaaattaa caagaacgta tgaaaataag ggtagtgaca
    15241 ttcagttggc taaaccttcc actaattaat tggagggaat agaaatggga aaataccagg
    15301 aattagcaga aaacatcgta aagaatatcg gaggaaaaga aaatatccgt agcttgacac
    15361 actgtgtgac gcgacttcgt ttcaaactaa aggaggaaaa taaagcaaag gatgatgttt
    15421 tgaaaaagat ggaagggata gtcaccatca tgaaaagcgg cgggcaatat caagttgtaa
    15481 tcgggaatca tgtgccagat gtctatgcag aagtactgac agtagccggg atttccgatg
    15541 aagtagaaga agaggtttct tcaagtagta atctgttcaa tcgattaatc gacatattaa
    15601 gtggctgttt ccagcctttt ttaggtgctt tagctgcagc gggaatggtc aaaggattaa
    15661 atgctttgtt cttgtttctc aaattttata ctgaaggatc gggtacgtac atcatgctga
    15721 atgggatagg ggatgcaatt ttttatttca tgccagtgat cttagggtac acagcagcga
    15781 aaaaatttca tctgaatccg atggtggggc tcgtgattgg tgcagcactt tgttatccga
    15841 ctgtacaagg agcagcacta caaagtggtt tccctgatgg cagtcctgcg ccttatagct
    15901 tgctgggtct tccggcttat gaaacatttt tgggtatccc atgggtgggc agcagttata
    15961 ccagtagcgt cgtacctgtt atcttcatta tcgcatttgc cggacaagtc caaaaaattg
    16021 ccaagaaatg gattcctgca gtcgtccaga cctttttggt tcctttttct gtgttattaa
    16081 tcgcacttcc tgctggcttt ttgattatcg gtccgattgt cagtatactg acagatctat
    16141 taagcacggg attccaagca ttgatggact tttctccagc tgtgtatggt gcagttctag
    16201 ggtttctttg gcaagtactg gtgattttcg gacttcattg gagtattatc cctcttgcga
    16261 ttatgcagct agcgcaaaat gggtggagtc agatgttagt aggcgtttat ggcgcgagtt
    16321 ttgcacagac agcagtggta ttggcgatgt atttcaagtt caaggatcaa aaaatgaagg
    16381 cgctttgcat gccagctgtg atttcaggaa tcttcggcgt aacagaaccg gctatttatg
    16441 gaatcacctt accgaagaag aagccattta tttactcgat gattggtggt gccatttcag
    16501 gaatctattt gatggcatct ggaacaatca gctacacaat gggcggatta gggatttttg
    16561 gggtggtaaa ctacatcacg gaaacagacg ccagtggtat gtttcaagcg tttatcggca
    16621 ttgctattgc ttcggtaatc gggttttcgc tgactttttt cttttggaag gatgaagcag
    16681 gtgaaacaga tgctatacag aaaaaatcag gtaaagaaat tgtaaaaaca ccgatacaag
    16741 gacaaatcgc tccactaaat gcagcgaagg atgcagcttt tgcacaagga acactaggtc
    16801 gaggaatctt gatctaccct gaaaaaggag aagtacgtgc cccttttgac ggaacagtca
    16861 tgaccctgtt cccgacgaaa catgcaattg gaatggtttc tgaaacaggg ctggaattgc
    16921 tgattcatgt cggattggat actgtgcagt tggaagggaa atattttgaa agcttagtgc
    16981 agcaaggaga aagagtgaaa caaggcgatc tgttgctacg cttcgacaaa aagaaaatcg
    17041 aaaaggaagg atacagttta gaaacacctg tgatcgtcac caattacacg gattatttgg
    17101 atattttgga aaaccaaggg gagacggtcg ggccagacga tgcacttatc accgcactga
    17161 cctgaacggt taggtgaaga atggaatagg cttaactatt ctttttattc cacttcttta
    17221 ttttcaaaat tgaaaggctc tttcatgatg gctgagctga tagggcgttt atcgaatttt
    17281 tgaccgacag aaattagatg gactaaattc tgttgataat tttctgcaaa aacacaacta
    17341 tataacacgt ctagaagata acaaattgat gtattgatcg taaaattacc aatttttgaa
    17401 tacagtcgct cgcgtgtcgt aagtcgcaaa gcggctgtac tcattgcaga tagcgttgaa
    17461 tcaccgatac tggtcaaagc taaaattgga acatgatttt gtttcaatat ttctgcggta
    17521 cgaagaatca ctttattttc acccgtataa gaaatcagga tcccgcacat atcgctcgtg
    17581 caattgtacg cttcatagaa tgattcacca aaagtggtga caattgtgac atccattttg
    17641 atgcgcttca ttttcagcat gaaatcttga gaaatcaaag tattcgagtt actggcgaag
    17701 atcacgattt tttttgcctg gagcagtaaa tacttggctt tttgcagttg gtcatgatga
    17761 atgagagaaa gtgtatcttg aatcgtcatc tgttctaaag aagccatttt atttgcgatc
    17821 gtcataatac cgtctgtggt ggaaaaagga agattcgcat ctacgtcttg aaaattccct
    17881 tcaagatagg ctgtttcagc taaaaaagca ttacgaaaac tgacccagcc atcaaaaccc
    17941 attttttttg ctacacggat gagtgtagac gggtggacat agcatcgctc agcgatctct
    18001 tggatggtca tttcgccaag tgctggagaa tcgcttaaga gaaactggat cacttcattt
    18061 tctgaaggag aaaaggagat ttctttgatt ttttcacgta ataacatgta gttaccttct
    18121 tcttattttt ttacgtaaat tataactttt ttgaaaatgt tttgtaaacg gatttatact
    18181 atataactta aaatagactt tttttgacaa gatatttaca aaaatccact agaaaacagt
    18241 aacttttgta aatgttactg gaaagaaacg gatttctatt gtttgttttg tttacaaaaa
    18301 agataatgaa agtgtaaaaa agtaaaggag tgagaacatg gcaaaaggaa tcaaaatcgc
    18361 tacgattggt ggaggcagca gttacacccc tgagttgatg gaaggattta tcaaaagata
    18421 tgaggaatta ccgatacgag aaatctggct cgtagatgta gaagaaggaa aagaaaagct
    18481 tgagatcgtt agtcagatgt ctcagcgtat gtgggatgct tctccgtatg aagtcaaaat
    18541 ctatgcaact ctggatcggg aagaagcatt gaatgatgcg gattttgtta cgactcagtt
    18601 tcgtgtcggt caattagatg cacgaatcaa agacgagcgg atccctagtt attatgggat
    18661 gattgggcaa gaaacaaatg gtgctggcgg gatattcaaa gcttttcgta ccgttccagt
    18721 ggtcttggca atcgttgaag acatgaagcg tttatgtcca aatgcttggc tgatcaattt
    18781 cgcgaaccca agtgggatgg tgacagaagc agttatcaga tatggcaaat gggataaagt
    18841 gattggatta tgcaatgtgc cagtaatggc gatgatgaca gaaccagcaa tgcttggcaa
    18901 gaaaaaagaa gagctgatct acaagtttgc cggtctaaat catttccatt ggcacaaagt
    18961 agcagataat aaaggaaatg accgcacggc agaattgatt gatcgtttat acgatgaaga
    19021 caatggattg ccgaaaaata tctttgatat cccgtttttc aaagaacaat taaaacaaat
    19081 gaatatgatc ccttgtggct accaccgcta ttactaccgt gaagaagaaa tgctggaaca
    19141 tgctttagaa gaatatcaaa cgattggtac aagagcgcag caagtgaaag aaacagaagc
    19201 agagctattt gaattataca aagatccaga attagaccat aaacctgaac aattgcaaaa
    19261 acgaggtggc gcttattatt cagacgctgc ctgtgaaacg attgcttcaa tctatggaaa
    19321 taaagaaaca cagatcgtgg tatctacaaa gaatgatgga gctgttcctg acctgccggc
    19381 agattgtgta gtagaagtca ctgcctatgt tggcgcacaa ggagcgagaa atgtagcgtt
    19441 tggttctctt cctgctgctg aaagaggctg gttgcaagta atgaagaata tggaattgct
    19501 gacgatcgaa gcagctgtga ctggtgatta tgggacagct ttacaggcgt ttacgatcaa
    19561 tccgcttata cgatcaggaa agacagcaaa acggatcatg gatgagttgt ttattgcaca
    19621 ccagcagtat ttaccgcaat tcaaggaaac aatcagccga ttaaaagaag aaggaatcga
    19681 agttcaagat gaactggcaa gagaattatc aggtaataca catataatgg aggaagtata
    19741 atgggattca gaaaagattt tttatggggc ggtgctacag cagccaatca atgtgagggc
    19801 ggttatgatg aaggtggacg cggactagca aacgtagatg ttgtgccaat cggaaaagac
    19861 cgttttcctg ttatcaccgg aaagaaaaaa atgtttgaat ttgatgagga tcatttttat
    19921 ccagcaaaaa ttgcaatcga tatgtatcat cgttataaag aagatattgc tttgtttgca
    19981 gaaatggggt tcaagactta tcgaatgtcc atcgcctgga gtcgtatttt tccaatgggg
    20041 gatgaaaaag agccgaatga agctggcttg aaattttatg aggatgtctt taaagaatgc
    20101 caaaagcacg gaatcgagcc acttgtgacg attacgcatt ttgattgtcc aatgcatttg
    20161 atcaaagaat acggtgcgtg gcgttccaga gaactcgttg gtttttatga aaatctgtgt
    20221 cgagtcatct tcaatcgata taaaggactt gtcaaatact ggctgacatt caatgagatc
    20281 aatatgatcc ttcatgcacc attcatggga gcaggactgt actttgaaga aggagaaaac
    20341 gaagaacaag tcaaatatca agcggcacat catgagttgg ttgcaagtgc catcgcaacg
    20401 aagattgctc atgaagtaga tccggagaac aaagtaggct gtatgctggc agcaggagca
    20461 tattatccat acacttgcaa tcctgaagat gtttgggctt ctagaaaatc agatcgagaa
    20521 aattatttct tcattgatgt tcagtcacga ggagaatacc cagcttatgc attgaaagaa
    20581 atggaacgaa atggcattca gatcgaaatg gaaccagggg atgccgcatt gctgaaagaa
    20641 catactgttg attttatctc tttttcttat tattcttccc gagtttcgac taccgacaac
    20701 gaactcttgg aacagactgc aggaaatatc tttgcttctg tcaaaaatcc atatctgcaa
    20761 gcaagtgaat gggggtggca aattgatcca ttaggcttga gaataacgat gaatgatatt
    20821 tatgatcgtt atcaaaaacc attatttatt gtagaaaacg gcttaggtgc agtcgatacg
    20881 ccagatgaga atggttatgt ggaagatgat taccgaatcg attacctggc agcgcatatc
    20941 caggcgatga aggatgcagt agaactagac ggagtcgatc tattaggcta tacgacttgg
    21001 ggatgtattg atttagtatc agctggtacc ggtgagatga agaaaagata cggattcatt
    21061 tatgtcgatc gtgataacca aggaaatggc acattagccc gttcaaagaa aaaatcattc
    21121 aactggtata aaaaagtaat tgattcaaat ggagaaaatc tttcgaacga ttgatcaatg
    21181 atttataaaa gtctattgtt tttcagcgga tttttcgagt ataataaagc tattcgagaa
    21241 acgcaagcag aacaatagac tttttttcgc attggctgta aagtatgctt acttgattaa
    21301 gtaaaggaga atctacatat gtatgatgta atcgttattg gcgcaggtcc tgctgggatg
    21361 actgctgctt tatatgcttc acgttcaaac ttatccgtat tgatgatcga acaaggtgcc
    21421 cctggcggcc aaatgaacaa tacggcagaa atcgaaaatt atcctggatt cgattcgatc
    21481 atgggccccg atctagctta taagatgtat gaaagtgtct caagatttgg gacagaaaat
    21541 gcttatggaa tcgttcaaga tatcaaggat cacggcagcc ataaagaagt catctgtgaa
    21601 gataaaagtt acgaaggaaa aacagtcatt atcgcaacag gctgtatcca ccgtaaatta
    21661 ggcgtacctg gcgaggaaga atttgctgga cgaggcgttt cttactgtgc agtctgtgat
    21721 ggtgcgtttt tccgtaacaa acgtctagta gtcatcgggg gtggggactc agcagtagaa
    21781 gaagccatct atttgacaca atttgcttct gaagtagtga tcgtccaccg tagagatgaa
    21841 ttacgtgcac aaaagatcat ccaagaccgt gcatttgcaa atgaaaaaat ttcctttatg
    21901 tgggatacag tcgttgacga aatcgttgga aacgaaatgg tagtgacagg tgtgaaagca
    21961 cgtaatgtca aaaccggcaa tgaatttgat ttagcagcag acggagtatt catctatgtt
    22021 ggactggatc cattaactgc accttttaga gaagcaggtt tgacgaacga agctggctgg
    22081 attccaacag acaacgaaat gaaaacgaat atgccaggcg tttttgccat cggagatgtt
    22141 cgtgaaaaag atttgcgaca aatcactaca gctgttggtg acggcggtat tgctggacaa
    22201 caagtgtata aatacttgga atctttagaa gaaacaactg cataagttta aaaagagtag
    22261 aagaacgggt tcaattgttc ttttactctt ttttttcgcg tgaaatttac tgaatctgat
    22321 ttatgcgaac acgtccaaca ccttttgata aaagaatcct ttcttgattt aagcgttttt
    22381 tggtcctcat actttcatat ctaataagtg aatgctatac ttattaagaa ccatatttca
    22441 gaaagaggtg ttattttcat gtcttgggaa caagtgtatg aacaatgggt acatgaagaa
    22501 aatttagaag aaaacttaaa aaaacaatta aatgatctgg gtgaagatcc tgaaaaactt
    22561 gaagatgctt tttatgcacc gttggaattc ggtactgcag gcatgcgggg aatcttagga
    22621 cctgggatca atcgaatgaa catctatacg gtaagacaag caacagaagg actagcacgt
    22681 ttcatggata cacaaggtga agaagcaaaa cgccgaggtg tcgctattgc ttatgactca
    22741 cgccatcagt caccagaatt tgcaatggaa gcagccaaaa cactggcaca tcacaatatc
    22801 ccgtcttatg tattcgaaag tctgcgtcca acaccagagc tttcttttgc agttcgtcat
    22861 ttgaagacgt ttgcgggaat catggtaact gcatctcaca acccagcggc ttacaatgga
    22921 tataaagtct acggagaaga tggcggacaa atgcctcctg cagacgcaga tgcattgacg
    22981 aaatatgtcc gtgaagtcag caatccgcta aaagtcgaag tattatctga cgaagaagct
    23041 aaacatagcg ggttgatcac gatcatcgga gaagaagtgg acgctgctta tctagaagaa
    23101 atcaaagcag tgacgattga tcgtgaattg gtagaaacaa tggggaaaga tttgaaactt
    23161 gtgtacacgc cacttcatgg aacagggaaa atgttgggcg aacgtgcgtt gaaacaagct
    23221 ggattcgaac aattcgtact agttcccgaa caagctgtgg cagatccaga tttcactacg
    23281 gtcaaatcgc caaatccaga agaacattca gcttttgaat atgctatacg acttggagaa
    23341 aaagaaggag ctgacttgct gattgcaaca gatcctgatg cagaccgttt aggcgcagcg
    23401 gttcgtttgc cagatggttc ttatgaagta ttgactggga accaaatcgg ggcattgttt
    23461 gctcaatata ttttggaagc acatcaatca agaggcactt taccagaaaa cgcagcggta
    23521 ttgaaatcaa tcgtttccag cgaattgcct acagcaattg cggaacacta cggtgctacc
    23581 atgttcaatg tgttgacagg gtttaaattc attgctgaaa aaatccaaca attcgaagaa
    23641 gaccattcac atacttttat gtttggattc gaagaaagtt atggttattt agttaaacct
    23701 tttgttcgcg ataaagacgc gatccaagca ttgcttttat tagcagaagt agcagcttac
    23761 tataaaaaac aaggcaaaac gttgtatgac ggcttgcaaa cgatttttga aacctatggc
    23821 tattttgcag aaaaaacgat ttctgtgaca atgagcggac aagaaggttc tgcgaaaatc
    23881 tctgctttga tggaaaaatt ccgtaaagaa gcaccgacag aatttgccgg agcaaaagtt
    23941 attcaaacag aagactttaa agaattgacg agaacagacc gtgaaggaaa cgtagaaaaa
    24001 ctaacaacac cgccatccga cgtattgaaa tatacattgg aagaaaatgg ctggattgct
    24061 atccgccctt caggaactga gccgaaaatc aagttttata ttggtgtaaa aggaagctct
    24121 acagaagacg cagccgaaaa agtagcctct tatgaagcga ttatcaaaaa gatgacagaa
    24181 gaataaaaaa cttgagactg atggaaaaag tggtaaactt tagaagtcag tcttttttca
    24241 agttggaggt gaatggattg ccagacacgc aaaaatcaaa agtagagaaa gtcagtcaat
    24301 tattcaaaat gttgagtgat cccactcgtc ttaaaattct gctatatctg aaagacgggg
    24361 aacaaaatgt gacagcaatc acccaagcag tggaaatgga gcagtctgct gtatcgcatc
    24421 aactacgttt attaagagaa aatcatgtcg tcaagtctca tcgcgaggga aaagcgattt
    24481 tgtatagtct tgatgattct catgtactgg atattttgaa ccagacactc aaacatgtgg
    24541 aacatcaata acgataggtg caaatagata aacactggag tgtgacaacg aaatttcttc
    24601 gttgtcacac tccagtgttt tttaagaaaa agacaaaaat gattaatcgc ttttttctgt
    24661 tgtttcagtt ccataataac tatgatcttc taggtctaaa gcattcaaaa taagcgaagc
    24721 cgtttcttca atagataaag atgccacatt gatcactaca catcctagtt tttcataaag
    24781 atcattcgca aaatcgagtt cagctctaat tttttcgata tcggaataag cagtatcagg
    24841 gtttaatccg taagagcgca tccgttcttt acggatatta tttaaaatat ctgggttatt
    24901 cgttagtccc acgatttttt taggatcgat ctcccaaagc tgtttgggaa tatgtgcttg
    24961 tgggatcaaa ggtaaattgg caacttttaa atttttgtta gctaaaaaca agctcaaagg
    25021 cgttttggaa gttcgggata cgcctagcaa aacgacatct gcttctaaaa aaccacgagg
    25081 atctttccca tcatcgtatt ttacagcaaa ttccattgct ttgatccgtt tgaaatagtt
    25141 ctcattcaat aaatggaggg caccaggttg ccgaattggc ttgataccgg ttaaacgttc
    25201 aatttctgat atcggtggcg tcatcacatc aaaactaaat aattgatgtt cttcacaaaa
    25261 agaacgtgtt atctcgatca gttcttgatt gattaatgta tgcaggacaa gtgctttttc
    25321 ttctaatgca tcttgcaatg cctgctttaa tgttttttca tctgtcacga acgttctgcg
    25381 gaataggttg aactcaacgg taggatactg agccatagta gcttgcgcta gttttgtcgc
    25441 agtttctcca gcagagtcgg agatgacaaa aaaagtaacg atttctgtag aatcggaaga
    25501 catggataaa acctcacttg catttttttt atgtttatta taccatactc tagaatgcgt
    25561 acttcgtaat cattttgatt tggaggaata agtcatgaaa aaacagacat tgatcgaaca
    25621 atcattagaa acattgaaaa ataacggttt taaatatact aaaaaaagag aagcattgtt
    25681 aacttattta gtgaagcgta accgctacgt atctgctaaa gaagtttttg actatatgaa
    25741 tcaggaattc aaaggggtaa gttatgatac gatttatcgg aatctccatg attttgcaga
    25801 gatcgattta ctggaagaaa ccgatttaaa tggagaaatg aagtttcgtt ttcattgctg
    25861 tcagggggaa atcggccatc accatcattt tatctgtaca gtgtgcggaa caacgaaaga
    25921 aatccatatg tgtccgatga attatttcga agaacagcta ggtggatgca cgatcgaagg
    25981 gcatagattc gagattttcg gaagatgtga aaattgtcaa taagggttta aataaaataa
    26041 catttgataa ttttaaaaaa aagcaagatt tccttgacgg tcaaaacagc attagatata
    26101 atatttacag gacagtcttg ttttttgaga tatatttcaa taacaattac ggttactttt
    26161 taagctcgga gggagggaat taacatgtca aaaacagtcg ttcgcaaaaa cgaatcactt
    26221 gacgatgctc ttcgtcgctt caaacgttcc gtgtcaaaag cgggtacttt acaagaatct
    26281 cgtaaacgtg aattctacga aaaaccaagt gtaagacgca agaaaaaatc tgaagcagct
    26341 agaaaacgca aaaaattcta gttctgtgat gaattggagt tggtagtgtg tcactactaa
    26401 gtagattaaa cgatgacatg aaagcagcga tgaaagcgaa agataaggaa tctttacaag
    26461 tcatccgaat gatcaagtca tctatacaaa acgagcagat taaagaaggt cacgacttga
    26521 cagaagaaga agaactaacg gtgttgtctc gcgaaatgaa acagcgacgt gattctttgc
    26581 atgagtttga agaagcagga cgtgacgatt tagctgaaaa agtaaaaagt gaaattgtaa
    26641 tagtcgaaaa atatatgccg gaacaacttt ccgatgaaga aattcgacaa cttgttcaag
    26701 aagcaatcac tcaaactggt gcttcatcaa tgaaagaatt tggcaaagtt atgggtgcaa
    26761 ttatgcctaa agtcaaagga aaagcagatg gaaaccaagt gaatgcgatt gtgaaagaac
    26821 tattacaatc ttaattttat catttaaact gcggacagtg attgtccgca gttttttgtg
    26881 ttcgtaaaaa aagaactaaa aa
//
LOCUS       DARPZF010000034        26423 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.035, whole genome shotgun sequence.
ACCESSION   DARPZF010000034 DARPZF010000000
VERSION     DARPZF010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.035"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(81..1028)
                     /gene="arcC"
                     /locus_tag="SLE65_001801"
     CDS             complement(81..1028)
                     /gene="arcC"
                     /locus_tag="SLE65_001801"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEI8449095.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(1143..2162)
                     /gene="argF"
                     /locus_tag="SLE65_001802"
     CDS             complement(1143..2162)
                     /gene="argF"
                     /locus_tag="SLE65_001802"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEI8449096.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(2253..3482)
                     /gene="arcA"
                     /locus_tag="SLE65_001803"
     CDS             complement(2253..3482)
                     /gene="arcA"
                     /locus_tag="SLE65_001803"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEI8449097.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            3943..4644
                     /locus_tag="SLE65_001804"
     CDS             3943..4644
                     /locus_tag="SLE65_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEI8449098.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(5253..6269)
                     /gene="tsaD"
                     /locus_tag="SLE65_001805"
     CDS             complement(5253..6269)
                     /gene="tsaD"
                     /locus_tag="SLE65_001805"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEI8449099.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(6266..6730)
                     /gene="rimI"
                     /locus_tag="SLE65_001806"
     CDS             complement(6266..6730)
                     /gene="rimI"
                     /locus_tag="SLE65_001806"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEI8449100.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(6737..7279)
                     /gene="rimI"
                     /locus_tag="SLE65_001807"
     CDS             complement(6737..7279)
                     /gene="rimI"
                     /locus_tag="SLE65_001807"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEI8449101.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(7263..7985)
                     /gene="tsaB"
                     /locus_tag="SLE65_001808"
     CDS             complement(7263..7985)
                     /gene="tsaB"
                     /locus_tag="SLE65_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEI8449102.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(8176..9156)
                     /locus_tag="SLE65_001809"
     CDS             complement(8176..9156)
                     /locus_tag="SLE65_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8449103.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(9180..10664)
                     /gene="galT"
                     /locus_tag="SLE65_001810"
     CDS             complement(9180..10664)
                     /gene="galT"
                     /locus_tag="SLE65_001810"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEI8449104.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(10676..11665)
                     /gene="galE"
                     /locus_tag="SLE65_001811"
     CDS             complement(10676..11665)
                     /gene="galE"
                     /locus_tag="SLE65_001811"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEI8449105.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            11913..12080
                     /locus_tag="SLE65_001812"
     CDS             11913..12080
                     /locus_tag="SLE65_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEI8449106.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(12142..13953)
                     /locus_tag="SLE65_001813"
     CDS             complement(12142..13953)
                     /locus_tag="SLE65_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HEI8449107.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTNENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(13950..14315)
                     /locus_tag="SLE65_001814"
     CDS             complement(13950..14315)
                     /locus_tag="SLE65_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HEI8449108.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(14478..14873)
                     /locus_tag="SLE65_001815"
     CDS             complement(14478..14873)
                     /locus_tag="SLE65_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEI8449109.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(14891..15853)
                     /locus_tag="SLE65_001816"
     CDS             complement(14891..15853)
                     /locus_tag="SLE65_001816"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEI8449110.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(15853..16065)
                     /locus_tag="SLE65_001817"
     CDS             complement(15853..16065)
                     /locus_tag="SLE65_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEI8449111.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(16086..16784)
                     /locus_tag="SLE65_001818"
     CDS             complement(16086..16784)
                     /locus_tag="SLE65_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEI8449112.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(16804..17346)
                     /locus_tag="SLE65_001819"
     CDS             complement(16804..17346)
                     /locus_tag="SLE65_001819"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEI8449113.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(17478..18482)
                     /locus_tag="SLE65_001820"
     CDS             complement(17478..18482)
                     /locus_tag="SLE65_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEI8449114.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(18479..19468)
                     /locus_tag="SLE65_001821"
     CDS             complement(18479..19468)
                     /locus_tag="SLE65_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEI8449115.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(19465..20271)
                     /locus_tag="SLE65_001822"
     CDS             complement(19465..20271)
                     /locus_tag="SLE65_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8449116.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            20437..21393
                     /locus_tag="SLE65_001823"
     CDS             20437..21393
                     /locus_tag="SLE65_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEI8449117.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(21470..21988)
                     /locus_tag="SLE65_001824"
     CDS             complement(21470..21988)
                     /locus_tag="SLE65_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEI8449118.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(22076..22225)
                     /gene="rpmG"
                     /locus_tag="SLE65_001825"
     CDS             complement(22076..22225)
                     /gene="rpmG"
                     /locus_tag="SLE65_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEI8449119.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            22453..22899
                     /locus_tag="SLE65_001826"
     CDS             22453..22899
                     /locus_tag="SLE65_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HEI8449120.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(23094..24989)
                     /gene="asnB"
                     /locus_tag="SLE65_001827"
     CDS             complement(23094..24989)
                     /gene="asnB"
                     /locus_tag="SLE65_001827"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HEI8449121.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNETIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEKWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(25314..26288)
                     /gene="bsh"
                     /locus_tag="SLE65_001828"
     CDS             complement(25314..26288)
                     /gene="bsh"
                     /locus_tag="SLE65_001828"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HEI8449122.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT         7859 a         5555 c         4521 g         8488 t
ORIGIN      
        1 aaaatccaga tggcctaaag gagaagaaat accacctgga tagctataaa tcatttcgta
       61 aatacgaaag acttaacaaa ttaatcagct acgataatcg ttccttcttc agaagctaaa
      121 agattctcga tattttctaa agaagtgatg attgccttag cgtttggttt tgcttcaaca
      181 aatgcaatag ctgcttctac tttcggaagc atgcttcctg gagcgaattg cttttcatca
      241 atgtattgtt tcatttctga aacagtaaca gtttctaatt tcttttgatc tggtttttgg
      301 taattgacat acacattgtc tactcctgtc aatacgatca gcaaatccgc atcgatgatt
      361 tcggctaatt tttctgaagc aaaatcttta tcgattacgg cttctcgtcc ttctaatcca
      421 gtagctgttt ctacaacagg aatcccaccg ccaccaacag agactgtgat aactccttga
      481 tcgaccagcg tttcgatgac acgtgcttct ttaatcgaga tgggtttagg ggaagcgact
      541 acttttctcc atccacgtcc agcatcttct ttgaatgtca cagtggagtc agcattcatt
      601 tgttctttgg cttcttcttc cgtgtagaat ggaccgactg gtttacttgg atttttgaat
      661 gaaggatcat tttcatccac aataacttga gtgactaaag aaaccacatc tttatcgatc
      721 cctttttcct tcagtacttc gcccatggcg ttttgtaacc agtaaccgat agatccttct
      781 gtcattgcaa cacatgtatc taaaggcatt gccggtgttt tctcagaatc agcagcttgc
      841 tgctgaatca ataggttacc gacttgcgga ccatttccgt gggagatgat caattcatct
      901 ccttgttcga taaatttcac taaatacttt gctgtttcca ttaacgcttc ttgttgggct
      961 tttgcacttg catccgtaga caagatggca ttgcccccta aagcgacaac tacttttcgt
     1021 ttggccattt cattcgtcct ttcttcagtt ctaccgaatt ttctagataa caaaacgagc
     1081 cagcgttttg tgattttccc tcaatgctga ctcgtttttt cgtgagatga atgtggttat
     1141 gcttaaacgc gagggataaa caagttacct aatgttgctg ccatgatcgc tttgattgag
     1201 tgcatacgat tttctgcttg gtcaaattga cgagcatatt tgctgcggaa gacttcatct
     1261 gttacttcca tttcagtgat gccaaagcgt tctttcattt gttcaccgta aacagtgttt
     1321 gtatcatgga aagctggcaa gcagtgcaag aagatcaaac gatctgtgtt gtgtgttttt
     1381 tctaccattt ccatattgat ttggtaaggt ttcaacaatt tgatacgttc ttcgaattta
     1441 tcttcttcac ccattgatac ccatacatca gaataaagga cgtctgctcc gtctacacct
     1501 ttatcaacat cgtcggtaat catcaattgt gcaccggatt tttcagcaaa gccttctgcc
     1561 attttgacga tttcttcttc aggttgtaat tcttttggtg caacgatacg catattcgct
     1621 cctaaaattg cacctgtgac taataaagag ttagccatat tgtttcgacc atctccgcag
     1681 taagcaacag tgataccttc tactgttcca aagttttctt ggatagttaa aaagtcagcg
     1741 atcatttgtg ttggatgcca ttcatcagtc aagccattcc aaactggaac accagagaat
     1801 tctgctagtt cctctaccat tttttgactg aatccacgga attcgattcc gtcaaacata
     1861 cgtcctagta ctttagctgt atcttctgtg gattcttttt tacctaattg gatatcattt
     1921 gcacctagat attcaggatg tgcacctaga tcgatcgctg cagtagtaaa tgcagaacga
     1981 gtacgtgtag atgttttttc aaataaaagc gcaatatttt ttccttctag atagtgatgt
     2041 gggataccac gttttttcaa gtctttcaag tgttctgaaa aatcgatcaa atattgtaat
     2101 tcttcttttg taaagtcttt ttctgctaat aagcttcttc cttggaatac tgattctttc
     2161 atattaaaca ttctccttta gattgttttt atttaagatt aaagaggaaa tcccgacggc
     2221 agctgacagt aagactgccg tcaggaaaca aattacttca agtcttcacg gacaagtggt
     2281 tggctcatgc agcgtggacc accacgacct cgtgacaatt cacttgaatt gatttctaac
     2341 actttgatgc catagctacg aagcaattcg ttcgatacat aatttcggtt ataagtgact
     2401 acaacacctg gagcgattgc caatgtgttt gatccatcat tccattgttc tcgaggtgca
     2461 acgatctcat ctccattacc agttgggatc agtacaagat catctaatcc aagagcagct
     2521 ttcatcgttt cgtgtaagtt atctgaatga gtaatcttga tatcatcacc atctggttcg
     2581 attgtaaaga catccatctt accgtcttta ctttgaattg ctggatggat agtgaattta
     2641 tcgtgatcta ccattgtaaa tacggtatcc aaatgcatca ttgcacggtt gttcggaatt
     2701 ttgattgcca acactttttc aaatcctgaa ttttttgcga ataggtggcg tgctaatttt
     2761 tctaaagctt tcgcattagt tcgttgagaa atcccaacag ctactacttt atcgcttaag
     2821 atcaattcgt ctccgccttc gatatgatct ggattttcac gatccaacca tacttcgatt
     2881 cctttatttg caaatcttgg atgatgtttc aaaatatatt ctgtaaacat cgattcacga
     2941 cgacgtgctt caaaagtcat cttattgact gtcatcccat ttcccattga tgcggaaggg
     3001 tcgcgtgtaa agtacaagtt tggcattggg tccatgtaaa atggatagtc atcgtctgct
     3061 gacagatcat atagactgct agaacgtact tcgatatctt ttgtacgaac cccagccatg
     3121 attttatcta ccatttcttg cgtttccatt gatagaagga actcatgaag accctctctt
     3181 acagcattcg atgcaatatg agattcatcc aacattttat tcaagaattg ttctttgaca
     3241 ttgcctgcgt caatcgcttc tgccgctaat ttttccaagt aaagagtctc gacgccttca
     3301 ttttgcaatg tcttcgcaaa gttgtcatgt tcttcttgag caatcggaag atatggaata
     3361 tcatcgaaca acagacgatc cataatatct ggtgtcaaat tttccacttc ttgtccaggc
     3421 cgtttcagta aaactgtctt taatttccct atttcagaga aaacgtgaat aggtttatcc
     3481 atgttgtgtt gcctccttct ttttgattac atgtatagga tatcctcctt ttgtaatcac
     3541 tttcataatt ttgtctcatt caaaatgaga cattcctcac attaatattc gataattaaa
     3601 taattaaacg tttttctatt tttaagcgta atttattcat tttttattct gtatacactt
     3661 tcaaaaaaat atttattcat tgaaaaaatt tttttgaata aattaaaaaa ataaattata
     3721 ttatcgttgt tagcgtttac tatatgtatt attgttgttt tttatacaca aatcattcgc
     3781 ttcaaaacaa attattcaat accattgtat attttttaca taataacaaa ttatatttgt
     3841 aaagtattaa aacttgtttc taatgttggt atgttaaaac tttacaaatt ctttaaaaaa
     3901 agtgacaata aatatagtga acaataagga gaggactttt taatgcgtgt taataaaatc
     3961 gattttcact tttcaaaact cagatatcaa cctgattttg aacatttctc ggatgaagag
     4021 ttccaacaga tcaaggaaca tactgttctt cgttcttata aaaaaggaca gatccttttc
     4081 gacgatggtg atcccagaca acggttgtat atcttgacca aaggactcgt tcgtttagaa
     4141 cgttatgatg aaagtgcaac ttattactac tatgactatg tgaatacaaa taaccttttt
     4201 cctatgtcag gaatgtttgg agaagagacc tacacttata cagctcaagc gatgactgat
     4261 attgaaacat tctaccttcc tgtttcctac tatgaaaaat tagcacgaaa aaatcccgaa
     4321 cagttgatct atatgataca aaaaatttct aaagtagttg aaatacatga attgcgtatc
     4381 caaatcggat tgacctctag cgcctttgac cgggtaaaac aaaatttatt cattttgaaa
     4441 gaagaattgg gcgtaccaac aaaagatggt catatcacca ttccttatcc gatcacctta
     4501 aaagaattag cagtgaatag cggcacgaca cgtgaaactg ctggacaagt aatcaaacaa
     4561 ctacgtgatt ccgggctgtt agattatgac aaaaagcgtt ttactttctg taagacagct
     4621 actactccag ctatgagaga ataacgcgaa caaaaataag cagtgaccct gataaatatc
     4681 agggtcactg cttattttcc tccctaaaac ttctgaaaga tccggcagtt ttagatcact
     4741 ggacaagact caaagatttt ctatgtgtgt ttcagttatg taatattcac tgtttgcaaa
     4801 aaatactgtt agattaacta gatgaagcgt cttgtcctca tccgatctag attattcgat
     4861 attcctcgac aataaacgat tactcagtga gggcaatcag aggaacggat aatgataaat
     4921 aagctgtaaa aaatagcaaa ataacaataa tgattaaaag tatgtaaaaa atagggcttt
     4981 gacaaaaacg tgtcacagcc ctatttcgat taaacggtgt gtacctgtca actcttcggt
     5041 cacaagtcat aatgttcata aacatgagga gctgtttttt gaaattgttc cttgtgaatc
     5101 agagttaaac gacaggctta cgaactcttg attaaacggc gttcaaaagc ttgcatacgc
     5161 ggtaataaga acagccaggt caaaaacatg agaagccgtt tttcctgggc tgttcttatt
     5221 acttgatgca gggcagcttt ttcacaacct ctttattcag ataaaaccaa gcttggatca
     5281 gcattcaact gatagctagc aaaatttctt ttttgcattt ccacatgtgc tgctgctcca
     5341 atcattgcag cattatctcc acaaagtcga agagggggaa tcactagttc tacctcaggg
     5401 agtttagttg ccaaagcatc ctgcaatcct tcacgcaacc cttgattggc cgctacacct
     5461 ccagctataa tcagttgctt gactggataa ttttgacaag ctcgaagtgt tttagtaatc
     5521 aatacatcga tcacacttgc ttgaaagcta gctgctaaat catttttgtc tagatcttct
     5581 ccacgctgtt gtgcattatg caccaaattg ataaatgcac tttttaatcc gctaaaactg
     5641 aaatcataat tatcttcatg gatcatcgct cgcggaaaat ggtaattatc ttttccctga
     5701 tgagctagct gatcgatttc ttttccgctt gggtaagaaa gacctaatac tcttccaact
     5761 ttgtcataag cttctcctgc tgcgtcatct cttgtctccc caatgatttc atatgatcca
     5821 tcttcttgca tatagactaa ttctgtatgt cctccgctaa caagaagtgc catcaatgga
     5881 aactggaatg gtttaaccag acgggctgca tagatatgcc ctgccatatg gtttacagga
     5941 ataagcggca attggtgtgc ccaagcaaaa gccttagctg cagaaatacc aatcagcaac
     6001 gagccgacaa gtcctggtcc ataagtgaca gcgactgccg ataaatcttc tgccgacaca
     6061 ccagcttcta ccagtgcatc ttccaagcat aaggtgattt gttctacgtg atggcggcta
     6121 gctacttcag gtactacgcc accaaaacgt ttatgactgt ttatttgaga agcaacgatg
     6181 ttagataaga tctctgttcc atttctaacg accgctacac tcgtttcatc acaacttgat
     6241 tcaatcgcca gaatcaattc ttcattcatt tcatcgtctc cgtttttaac tttctgctca
     6301 taatgatcgc atcttccgtc ggattgcgat aatatgattt ccgtttacct aatatacgaa
     6361 acttttctga ttcataaagt tttcttgctg cttcattaga tagacgtact tctaaaaaaa
     6421 catgcagcga atcttttatt tgttccgtaa tcagtaattg taacaaatgc cgtgcatgcc
     6481 cttttccttg ttctgaaact gcaacagcaa tatttgtgat ctcgacttca tctattactt
     6541 tcgagtatcc aataaagcca cagatctggt tatcttcagc taaaagcaga taatcagagt
     6601 gaggctgttg gatgtctgcc aaaaactgca ttttcgtcca aggtgaacca tgtggataag
     6661 cattttcgct aatcatccat acgcattctg ccaagtacgc ttcatcaaaa tctttttttc
     6721 tgcaaatcaa ctaatctcac tcattttcta aaagttttat catatccaac gcatcttctt
     6781 ttgtttcagt gtaatatctt tttttgatcg ttgttgcttg aaaccccaat ttccgataaa
     6841 gtctttgtgc atcttgatta ctcatacgca cttctaatga catcgtctca cagcgattca
     6901 ttatagcaaa gttctcgatt tcgtcaataa gcagcgaacc gattcgttta cgctgatatg
     6961 ccggtcgaac ggcaatattc gtgatatggc aatctaaacc gaacgctctt gaaccgataa
     7021 aaccaatcat tcttccatta tcaaagatac ctagatatag atgaggaagc ggtgacttca
     7081 attctgatat aaaggcactt tttgtccatg gcaattcgcc attatagact tctcgttcga
     7141 catccagcag ctctttgata tcttctgtag tcaattctct tagtacgtaa cgacgatcga
     7201 tttgttcgac tgttttttct gtataaatca ttttatcttg aaaaaagctt ctggcatacg
     7261 ctctaaattt tttcaacata actttcgtct ccaggtgtgt gcgtctccaa ccatttttct
     7321 tctgcttcta ctcgttttaa atagcgagga agaaaagctt gtttctctgc aactggttca
     7381 actaaagcac ctaattgagc cacagttaca ccacttggaa tatcccatgc tggaactgta
     7441 ttaatcatcg cactaggcaa tatttccttt atttcagaga agaatttgtg acaatcactc
     7501 ccgacgaaat aaatagcttc attcagcttt tgtagttgtg tgaacaaatc agaagcagaa
     7561 atatgtacat cttcaagtac agtttctaat ctattttctt tccagcggta tgccccagcg
     7621 tatacatttt ttcttcgagc atcaaacatg ggcacaataa tattatccac accgatgcaa
     7681 ttagccgcga tggttttcag actagatact cctactagct ctttatctaa tgtataagca
     7741 atcgtttttg ctgtcgttac acctatacga agccctgtat aagaaccggg accatcagaa
     7801 accgcgattc ggtcaatgtc ttttggactt atttgaagat ctgcaaacaa ttggtcgatt
     7861 gcaggcatca gtgttacact gtggttgcgt ttgatatttg tttgtatttg tccaagaatt
     7921 tgttcgtctt ctaccacacc gatcgccaaa gtttggtttg cagtatctat tcctaatgta
     7981 atcatatatt tgatcctttc tgctatgaca ttctcgcctt ccattgtagc atactttttt
     8041 attctgagga tgaaaatacc aaaggcaaaa ctagtacaat aatacatgat tatctgctgg
     8101 cgggcaaatt ttgccccttc ctgaaacaca aaaaagctgc ggtatcactc cattttccca
     8161 cagcttttcc atcttttatt tcgttgattc tcgaataatc aactctgttt ccacaataat
     8221 ctttcttgaa accggtgctt tggaattact taattgaaga atcgtctcca ctgctagctc
     8281 tcccatccat tcggtataaa cttttacagt agaaagcgag ggcgttacat atttcgctac
     8341 actgacatca ttgaagccca tcacagaaat atcttctggt accactaaac ctttttcttg
     8401 aatcgctttc agtgcgccaa tcgctaatgc atcattagct gcaaaaagcg catcaggaac
     8461 atgcggattc gtttttaaat actgcttcac tgcttgatat cctgactcga cagaaaaatc
     8521 tgcttcgata attggacctt cgtcgtagcc tttttctgcc aaaacttgtt gaaatgccat
     8581 aattctggga tcttttagcc gctgatggtt tttcttcgta tattctgttc cagcaagcat
     8641 agcgatatgt tgcgctttat gggagacaaa gtgttcaatg actttttgaa cacttgactt
     8701 aaagtcgaca actagagagt cgattccttg agaagtgccg tcagaatcta ccaaaagcaa
     8761 ggcattttgg gatcctttca tttctaataa ctgagcttcg tcgaattttc ctagtgcgat
     8821 cgttccatct gccggaagat cactaatgga atcccacgtt tctttcaata aagtaacgtt
     8881 tgcttcttct gccttttttt cgattcctag gcgaatagat aaataataaa gatcttcaag
     8941 ctcttccgta tcgtcgtacc actggatcag gcgaagcgtt tgcttagtat ttgctgcatt
     9001 tttacgatgt ttcgtataat ttaagcgttc tgctgcttca aaaatttttt gctttgtggc
     9061 taagccaacg gaaagatcag gatcatagtt gagaactctt gaaacagtag caggagaaac
     9121 tcctgccaac tgcgcaatgt ctttaattgt tgccatttgt ctctcctcct tttttacgtt
     9181 tataaaatcg cagtaaatcg ttcaaacgct gcctgtcctt tttcatctcg cttgaatact
     9241 ccagcgtctt ccagtacacg tgcaaaaacc tgacctacag atttttgtac gacatcggtg
     9301 accgtatctt tcgtcaaatc aggatgttct ttttttaatt gttctgccca cggacgatga
     9361 tattcagcca tctggttttc ttctcctaat aagaaatgct ctacttctac tagttctggt
     9421 ttcaaacgag gtggtaaaac agcaagcccc attacttcga tcaacccaat gttctccttt
     9481 ttgatatgtt ggacatcttt atgtggatga aaaatcccat caggatgttc ttctgaaaca
     9541 ttgttgtctc gaaggacaag gtccaactca aagtaattgt cccttcttcg tgcaattggc
     9601 gtaatcgtat ggtgtggtgt accatctgct gaaaaagctc tgatagatac tgtttcatcc
     9661 gaatatgctt tccatttttc caatactgag ttagctgctt caataagcaa gtttttctct
     9721 gttgattgca aacggatcac agacatcggc catttcacga ctcctgcgat gacttgcgga
     9781 taatcttcta gtttgataag tttttctatc ggtgcttttg ccataggaaa ttcatgacgt
     9841 cctgcctgat aatgatcatg agaaagaatc gatcctccaa caattggtaa gtcagcattc
     9901 gaaccaacaa agtaatgagg caagacttca gtaatccgaa gcagtctagc aaatgtttcc
     9961 tttgtgattt tcatcgggcg gtgttgttct gataaaatga tcgaatgttc attgtaataa
    10021 gcataagggg aatattggaa tccccagctt tcaccgtcta gattcattcg aataatccgg
    10081 tgattggtgc gggctggata gttcaagcga cctctatatc cttcgttttc catgcaaagc
    10141 atgcaggtag gatagtctac ttttaccgcc tcgcgttctg ctgcgatttg ttttggatct
    10201 ttttctggct tagataaatt gattgtgatt tccagttcac catactccga ctctgccgga
    10261 aatttgatgt tttttgcgat ggctcttgtt ttgatgtagt catttttctt acttaaatta
    10321 aagaaatact cagttgcttc ctctgggctt ttcgaatagt gctgtgcaaa gaatgcattg
    10381 acgactgaag gtggcggtgt gagaaaatcc attaattgcg cttcaaaaat ctcttgttct
    10441 gctggcaatt ctgaaagaac accattttct cttgccttag cgacaagctg atccaataag
    10501 tctacagatt cttccttaac tggtcttact tcaatgcttt ctagagcatc ttctcctacc
    10561 atccctaaaa gacgattctg taaatataag cggtccattt ccatccatcc gccagcttcg
    10621 atcgcaagtg tggcaaaatc acaaatcgtt tgactgattg acatatctca ttcccctatt
    10681 cttcataacc atttggatgg ctgacatgcc aatcccatgc tgttttgata atcgctttga
    10741 tatctgtgta ttcaggtttc cagcccagaa tctctctcgc tttttcactt gaagcgacta
    10801 atcggctagg atctccagct cttcttggtg ctatttctgc tggaatttct tttcctgtca
    10861 cttctctagc tgcttctagc atttccttga ctgagtatcc tttgctgctg cctaaattga
    10921 agaagttgct ttcatttcct tctttcaagt attccaaagc taaaatatgt gcagcaatca
    10981 aatcttctac ttgaacataa tctctgatac atgttccatc tggtgtatca taatcgtctc
    11041 cataaacagc caaggctttt ctttgaccaa gagctacttg taaaatgatt gggacaagat
    11101 gcgtttctgg tgtatgatct tctccgatag atgcatctgc ttttgctccg gctacattga
    11161 agtagcgcaa agcgacatag cgcatgccat atgcttggtc acaccacttc atcatttttt
    11221 ccatcatcaa tttactttca ccatacggat ttttaggatt agctggtgta tcttctgtga
    11281 ttggagactc tttcggctct ccataagttg ctgcagtaga agagaatacg attttattca
    11341 cgttgaactc gtgcatgact tcaagtaaga tttgcatacc gtatacgttg ttgttgaaat
    11401 acatcaatgg tttttcgaca gattctccta ctaaagagct tgcagcaaaa tggattactc
    11461 cttcaatcgg ttccttttca aatacggaac gtagaaattc tttatcccgg atgtctcctt
    11521 cataaaaatg agcatctgga tgtactgctt gtttgtgacc tgtgagcaaa ttatctacca
    11581 cagctacttg ataccccttt tgaactagct ggtctacagc gtgcgaaccg atataaccgg
    11641 ctccgcctag tactaaaatt gtcataaaaa acactccttt gattagtaaa attgtgtttg
    11701 ttgattctat ataatttaaa aaacgaagtt tacttttatg gtgaaaacaa acaaagtaaa
    11761 atttcgtaaa ttcatatggt aaatttataa taaaacattt agtaaacatt ttcaaggatt
    11821 ttttgcaaag gtttacaaac aaacgtaaaa ctagcctttt tttctctttt gttccataat
    11881 agatataaca aataataaat gaggtggatt caatgaaaaa atttgtatct ggaatattag
    11941 taggaagtct ggcaacagcc gctgccgttg ctggtttggt tgcttctgtg aaaaaaacag
    12001 tgatcgatcc aattgacgaa aaagaagcaa tgatcgaaga aaaccgtaaa aaagcaatgc
    12061 gtaaacgcgt ttctcgttaa taattattta aaaatacgca tgaagacttt ctaaaaaaca
    12121 gataagtcat catgcgtatt tttatttgtc agtcaatata agttgtgcta ttttatctgc
    12181 ctgtctcaga ttccatggat ctgtataagg tctagctact gctgcagtta gccaatccac
    12241 accttcaaca ggtattccat agcaataaaa gtcagactgg atttcccctg aagcatcaat
    12301 cacgcgattc gtacctcgct caacatctat agcttctgaa tgataacttc ctgtattatc
    12361 tgaaaatgaa aaagggcgaa caagtttgtt ttccttcaaa ttttttatga caggattact
    12421 tgaacgagaa aagcttgttt gtggcaatcg agcttcaatc aaatagcgac tgctgatttc
    12481 tttatcttgt agagaaataa catagcggtt gtgcttttgc tgaatatcaa atggcggttc
    12541 gatcaaatga aaaatacccg catctatcag tgctgctaat tctttcgtcc gaatgattgg
    12601 cggaccgatc gttaaaaagc tatttagatg agtaaaccat ccccatagta tttctttgta
    12661 ttccttagca gaaaaaacgt gccattcaat agcctgccgg attggatcac gccagtcttt
    12721 taatgcatca aatgttgaag caaatgctcc tgtgcaattg cctttttccg cttcttttat
    12781 ctgcccttca ataaatattc ggctagcttc tgaaaagggc tcattctgat aggcaagagg
    12841 agtttctaaa tacgaccaat cccatctata agggattagt gctggatgct ttccgagaca
    12901 ctcctctgaa gagagggaga gaaaatcatg ctcaaaattt ttctttggaa tcggcaagtg
    12961 atattcttcg atgattttct tgtaataaaa caactcaacg tcttttttca gatagtcaaa
    13021 aaatgtttcg ccagtcaaaa atcccgactg atgccattgc tccaggtttt catttgttag
    13081 taaccgtggc catgccattg ctccgccttg cttttgattt cttcctcgag ggtaataagg
    13141 gagccccctt cttgatccac tgtatacaat cggttccttg cctgatggat gatagaccag
    13201 ttttcccttt tcgttctcga agcgccctcc tcttgatact gtaaacaatc cgacataatc
    13261 aaaaaaactt aagcctagac ctcttaaaaa gacattttct ttaggcggta tcttcgaaag
    13321 atctacatct gcaggattag aaggaagctg atacagtaaa acatttttct ttgcgtagtc
    13381 tacccacact ctttcttctt ctgtctcatc attttcccag tgaccgcttg ctaaaacaag
    13441 ctgatcgata gaatagcttt gctgatctgt ctgtaaaaga taaccatctt ttcttttgct
    13501 tacttttttt actaaagaat aaacaaactg aatagaagct ggaaattctt cttgcaactt
    13561 tgagaaaaac cagcgttgat agagtccgta taaacatcga gtagattgct gatctttttc
    13621 cagacgattg atttcttcta taattagttg cttatttttg gttaccgtct gttcgatata
    13681 atctgtagca ggtcctttac tccattgaaa caagttgggt ccctgtgtta ccaatcctcc
    13741 actggacaat gtttcatctg taaaaagcgt cacttgttga gaaacagaat tcattaataa
    13801 ctccggtggc tgattcaacc gccaaactcg acctccagga ccattgggat cgaaaagaaa
    13861 aagttcaaga gaatgtctgt cctgattatt atggagaatc ctttctgcta cacttaatcc
    13921 tctaggtccg gcaccaatga tccctatttt catttgcatg cctccatttc gataaatttt
    13981 ttcaataaaa cagcatggtt ctgatgttca ttttttgcac cataaacaaa agtaatgact
    14041 ggatgttctt tcataagttg actgagttta aaaatagctt gcttcttttc ttcttcgaaa
    14101 atcaattctt gctggtattt ctttgcaaat gaagcaaatc gttctggtac atggtcaaaa
    14161 gttttgcgtg cttcattact aggtgcaatt tctttcaacc acagatctaa ctgcgctttt
    14221 tcttttgaaa ttcctcgtgg ccagaatcta tccacgagta ttctatagcc atcctctttt
    14281 tcagcatcaa ggtaaacacg ttttaatttg atcatagttg tttccttctt tctacctttt
    14341 cgcttagctt atatatgtag ataatagcac aaaataaaaa aaatgaacgg cacaactatc
    14401 cattgcgccg ttcatgtgat cttggtcaaa atctaatgat tgattcggtt tttaaagctg
    14461 tcatacaatc atctgtttta tactttttta cttttgattt ttccagacca tccgtcatat
    14521 ccacccttaa gtaaataaat ctcttgataa cctgctttac gtaatttatt tgctgtacgg
    14581 atgctcaaac ttttcttttg atcgtaaata tagacaggct ggtcttttcg aatagatcct
    14641 aatgaatctt tcaaaacagt gtaagggatg tttcttgcac ctaaaatatg cccagcatca
    14701 aacacatctt tttcgcgaac atcgattact tgtgcttttc tcattccttc tcgaaattct
    14761 tcttctgtca aagtcgttgc tgaacgtttg gccattactc gtagatagac ttcccaaagg
    14821 atgattgcaa gcacaatcaa tagcaaaatg atattaatta cccataaaac catgtaatgc
    14881 ctccgttttt ttaagcaaat ttcaaggcta atgaggcagc accaatgaca ccagcttcat
    14941 taccaagctc tgctaatttg atttttgttg attctcttac ttgcgggaaa gtaaattctt
    15001 taaaatattt ctctacacgg ctacgtaaaa attctcctgc tgccgatact cctccaccta
    15061 acacgatact tgacggattt aatgtattcc ccaagtttcc gcaagctaaa cctaagtaga
    15121 agcatacgcg atcaacaacc atcaatgcaa acggatcgtc ttcttgagcc atttcaaaga
    15181 tatctttact tgttacttct tctccgttgt ctagcattgc tttcagtttt gaatcccctg
    15241 cgtattcttc tgccaagaaa cgacctaggc gtaccacacc tgtagcgcta gatacagttt
    15301 ctaaacatcc gcgtttaccg caagtacatt cgaacccttc aggatccaca gtgatatgtc
    15361 cgatttctcc tccagctccg ctcacgccgt gaatcaaatt tccgccagca acgatacctc
    15421 cgccaacacc tgttcctaga gtaacgaata caacgtctgg atcgttttct ccagcacctt
    15481 tccatcgttc acctaaagca gcaacattcg cgtcattatc gatagcgaat ttgattcctg
    15541 ttcctgcctc gatcagtttt ttcacaaatt gaacttctgt ccagtttaag ttatacgcac
    15601 caataaccgt tccagcttcg ctgtccacgc ttcctggggt acccatgccg attccgataa
    15661 agtcttcggc tttcatatta tataaattca aacgatgatt gattgattca atgatttcag
    15721 gaacgatatg cttaccatca tccaaaatat tggtatcgat gctccatttt tgctgaatct
    15781 ctccttctgg tgttaaaatt gcaaattttg ctgttgttcc acctaaatca atcccaataa
    15841 tcttcttgtc cattacaaat ttcctttctt tcggctttct tcaattcggt gctctctttt
    15901 taatatgcgc cacgctgtca tgtatgtatc atgatcaatc aaacggctat catacagatt
    15961 acgcaattcg atagtcatta attcaatgtc atagatgcgt gcacccacat agataaagat
    16021 gccaaatttt ttgaacagct gctgtacatc atataagctc tccatcttta agcacttcct
    16081 tcatattata caagtaaacc atattttttt aaacccagta aaatacatat tacaaaaaga
    16141 aatacaaaaa ctagtgtaga aagaatcctt tggtgtatcg aatagcttgt ctgttgtttc
    16201 ggtagaccca aaacattccc taacactaat ccgccaatta gcccaccgac atgtccccaa
    16261 acatctacag aggtatccag aagaccaaaa acaaatgtca acacaataaa taaaagaaaa
    16321 tgtctgacta gctgctggat cgctgggtta tgtttaaaat gaaaccctaa gataaacaac
    16381 gcaccgaaca aaccgaatat cgaagtactt gcaccaccag acagaacatt cgcttcgtta
    16441 aaagcaaagc ttgctgtatt tcccattatc ccgctgaaca tataaatcaa gaaaaaacgc
    16501 caatggccat agattgcctc gatttgctgc cccataaaat acagtatcag tgagttcatt
    16561 acgaaatgca tcagtccaaa atggatgaag attggtgtca ctaaacgcca ccattcattg
    16621 aagtgaacaa gataaggacc atacattccg gcataataag ggatctcaag tcgcggaaat
    16681 aattccatca tgaggaagac cgctgtctgt atccctaaaa aagcataggt ccataacggt
    16741 cgtcttaacc atgcacgcaa ttttatttgc tgttgataat tcatgaaaac ctcccatttc
    16801 attttagtca ataaacaatt gttggatctt ctgatcaaag ctctccggtt gccattgttc
    16861 attcaattgt tcacgaaaaa caaggctaca tgttttttta tgaaaattat ttaaataccg
    16921 gtcgtaataa ccaccgccaa aaccgattcg ataaccggct ctattgtaga taatacctgg
    16981 tacaatgagg agatcgatca tctccggcaa atagagcttc tctgattgtg gctcaagaac
    17041 accaaaactc gaacgtacaa gaacggactg ttcatccatt tcataaaacg ccatctgacg
    17101 tttcggcaaa gttttaggta caactatttt cttttgttct ttttctgctc gttggataac
    17161 cggctgtgta tccagttcaa attcattcga taaagtcgtc cctatcactt ttgctgactt
    17221 ccagtactcg ctggcgaata gctgtttata gattcgctgt tctttttcct ttttcttgcc
    17281 acttttggcc agatttttca gcttttcgat tcctttccgg cgtaatctta ctttcaattg
    17341 gtccaaaaac tcacccttcc ttctctcata aaatggtata ggaaaaaaag aaaaatagca
    17401 atcgaacttt caaataaatg cataaataga ataaaaagaa gacctagaaa tgattggcct
    17461 tcctttttta atgaatttca actgttcagc gcgtgttttt gtctgataaa aagtgcatac
    17521 agaaaatatg gcgcaccaaa aagggcaatc aaaattcctg taggtacttc cccacttagt
    17581 agaatcactc tagcaaccat atctgcacta agcagaaaaa tggaaccgaa caaaccgctc
    17641 agaacaaagg tccagttatt ttctttacgt acgactagct tcgcagcatg aggagctagt
    17701 agtcctacaa aagataaact acctgtcacc gctacactac cgcttgccaa agcaacagct
    17761 aacaacaaaa ggattttttg acttttagcc acgttaaggc ctaatccttg cgcgcgttct
    17821 tgaccaaatg atagcaatac aatcctctgt gcataaagtc ctcctagcgg aattaagata
    17881 accgcccatg gaagcaatgc ccaaacataa ggccagctcg caccccagat tgatcccgct
    17941 aaccatgcat tcacaaatcc ataattttcc ttagataatt ggatcgtgca tagcaatgtt
    18001 aatgcagaaa ggccggcatt aacggcaata ccggacaata agattcgatt catacccaaa
    18061 aagccatttc gatcataggc cgcaagatag acacagcaag cagctaaaac accacctaga
    18121 aaggctacaa ctagcaatag aaacggcagc gaatagtgcg aaaagaaacc taaataaagc
    18181 atcactaaaa atcctgctcc ggcattaatg cccaatatac tagaatctgc caattcattt
    18241 cttgttactc cttgcaagat ataaccagaa acgccaagac aagctcctgc taataaactg
    18301 atcagtaatc gaggaactcg aaattctcta acaatcagcg ccaaagaaga tgattctttc
    18361 cctatgaacg tggcaaaaag ctgatccagg taaataaaag gcgtaccaat cattaaacta
    18421 cctatagaca ggatgacaag tacaaaaagc aagaaataga acgtccaata tatttttttc
    18481 accgttgttc cctccttact tgtatcagta aaaacggaac gccaatcaat gcaatgacta
    18541 atccaaaagg tgtttcaaaa gggggattga tcatcctcgc tgtaaaatcc gccaacataa
    18601 ccaatccacc gccaactaaa aaagagacag gtagaacata acgatagtcc gttccaacca
    18661 ttccgcgaac aactggcgga accaacagcc caataaatga aacaggtccg actaacgaaa
    18721 cggcaatggc tgctaacact gcaactagac agaaaacaat caaccgcgtt cgtttaggat
    18781 gacttccaag agctaatgca tgtgtttcac tcaaatgaat caaagatatt gcttttccta
    18841 atgaaaaaga aaccaaaaca gcaagtatat ataaaggaaa caatactgct aattgtttcc
    18901 atgtgatatt ggcagctccg cctacaaacc aaaaagcaag atcctgctgc agattaaaga
    18961 attgggtaag tgcttggctg atagcagtaa aaaaagaact aatagctacg ccagctaaaa
    19021 tcagctgtaa aggattcatg cccattttcg aaaactgcaa aaaaccaaat acgagcaaag
    19081 ttacagcaaa agaacctgcc aatgacatta gaaacacaga aaaatcagaa gctttaggcc
    19141 aaaaagcaaa actaagggcc attgccaacg aagcacccgc gttgattcct agtaagcctg
    19201 aatctgctaa aggatttctt gtcactcctt gcatcaatgc accgctcaat gcaaaacaac
    19261 tccctacaag aaatgctccc gccacacgag gcaaacgaat atttcgtatg atttggtgac
    19321 tttgttttga tctatcaaaa tcaaacaacg cctgccaaaa atctgctttt cccacagtcg
    19381 ctgcgccatt tgaaagagca acaaaaaaaa taatcaaaag aacaaaacag accaaaagca
    19441 ggagtctatt tttcttcata gtcctcataa ttgatcctcc tgctcttttg gcaacaaatc
    19501 ataggttaga aaaactggtt tatttgttct tggaagcgtg acaatcgttg catcaatctc
    19561 aaatattttt ttcatacact cttttgtgat cacttcttca ggtgtacctt ctgtgatcaa
    19621 cttaccgttt ttcattgcta ataaataatc tgaaaaacgt gaagcatgat taatgtcatg
    19681 aatcgacatc aagatcgttg tttgtttcat ttgattgatt tcagtcaata actgtaggat
    19741 ctctaattgg tgtgccggat ctaaaaatgt tgtcggttca tccaagatca agatatctgt
    19801 ttcctgagca agcgccatag cgatccagac acgctgggtt tgtccaccag acagcgttgc
    19861 gatatcccgc atacgaaatc cagctagacc tgtagcatcc aacgcccact cgattgcttc
    19921 atgatcttgc gtgtccatgc cactgaacag tttttgataa gggtatcgtc cgtaagatac
    19981 tacttcttct actgtcatac ctgtagggtg ttcactagtt tgtgctaata atgcaatttt
    20041 ttttgcaagt tcttttgaac tgtatgtaga gatatcagag ttattgacaa tgatctttcc
    20101 tgatttcaca ggtagtatac gggtaaaact tttcaataaa gtagattttc cacttccatt
    20161 tggcccaatc aaactagtga ttttcccttc aggaatcgta acagacatgt tttcaatgat
    20221 ttttttgttt tcgtagccgg ctgcaatgtc agctgctctt aatctcgtca tttcacccat
    20281 cctttcgctg aaaatcattc tcaattatga cgctgtttca acatttcgtc aagcgctact
    20341 ttcatatcta tagccaaatg aagcggttga cagcgttcga aatatcagga ataataacca
    20401 atgagaaaga ttctcaatta tgttaggagg aaagaaatga aattaaaaac aaaagtattc
    20461 acattatcta gcatattgct gctggctgga gtactgagcg cttgctcccc ctcttcagat
    20521 aaagaaacag ctacaactgc caattcgacg acttcatcca atagtactca tacagtcaca
    20581 gatacacttg gacataaagt agagattcca aacgcgccca aacggatcat cggcagttac
    20641 ttagaagact atctgattgc actaggggaa aaacctatcg cccagtggac tgttggcagt
    20701 ggttccattc aagattatct gcaagatgat ttaaaggatg tcccaacgat ttcttatgac
    20761 cttccttatg agaaagtgtt aagctttgag cctgatttgc tgttgatttc ttcttccgct
    20821 actgtcgaag gcgggaaata cgaacaatat agcaaaatcg cgccaactta tgttgtaaaa
    20881 aacggaacag atgtcacatg ggaagaacaa ctaaaagatg tcggcaaagc tttggcaaaa
    20941 gaaaaagagg cagaaaagat catttccgat tatcaaaaat ccatcaagaa aactcgagaa
    21001 gaactagcag ataaaatcga gaacaagaca gctgcagtgt tgtgggtgac caacaactca
    21061 gcctttatgg tcagcaaaaa tcggtcaagt ggaagaatcg tatacgacga tctggaattt
    21121 ggtgttcctg atctagtgga agaggtctcc aaaaaagcca cttctgactg gtctgctgtt
    21181 tcctctgaaa agctagctga attagatgct gactacatca tccttgtgaa cagtgacaaa
    21241 gatgctgcca tgttcaatga accaagctgg aagaatctta aagcagtgac agacaatcat
    21301 gtactgcaat tcggacctga atctagttgg ctatataacg gacctattgc cagtcaggaa
    21361 atggtcaatg atatcaaaga aaaactaaat tgattttaac taaaaaaagc atcttcacga
    21421 ttagtcgtga tatgcttttt ttcttattaa caaactagac gcatagattt tattcttctt
    21481 ttgaagcaac cctatttttt actctttccc atttttgaaa acgatgggca tatagatttt
    21541 cttgatccgt tatcccctca tactcctcta taagggcgaa gtctgaaaaa tcaatattcc
    21601 caatatacgt atcgccttca aacgtgctat cgatcaatgt tcgccagatc cgaccagtgt
    21661 aaggaagaag ttcttgaaaa atccgactac cacccgaaac atagatatct tctgagatcg
    21721 tttgactata cgacaaaagt tcatcgatcg aatgcattac ttccgcattt tctttcgtgc
    21781 gaaaatttgg ctgcgttgtc aacacgatga tatggcgata aggaagtgaa agatccccca
    21841 ttccttcata ggtctttctt cccatcacta aaattcgatc cattgtatgt tcgcgaaaga
    21901 aacgcatatc atttggcaat cgccatggta acaaaccatt tttgccgatc agaccatttt
    21961 tatcttgtgc ccacatggaa ataaacatat tatccgctcc ttatgatttt agatgttttg
    22021 agataaaaaa agtctcaatt ctttgaccag caaggaattg agaactttaa aaacattatt
    22081 ttgtttcacg gtgcaaagta actttgcgtt cgcgtgggca atatttttgt ttttccaaac
    22141 gatcaggatt gttacgtttg tttttgcttg ttagatagtt acgttcttta caagaagtac
    22201 actctaaagt gatgtttacg cgcatgtttt tccctcccat ttttacaaga atcctctaag
    22261 atgactctca gacttgatta tcttaccatg attttttcta gattgctagt gtttttcacg
    22321 attttgttaa gtaaaactac ttgacgataa atacaacggt tttacttctc aaacaaaatc
    22381 tttttctttt tgtataaata cccttacact tgtttatata gattatgttt tttaataaag
    22441 ggggatacta atatgccatg gaacatgaag gactttcctg catcaatgaa aaacttagat
    22501 aaattgacaa gaaaaaaagc aatcgacatc gcaaatgcat tattagatga agggtaccct
    22561 gataaccgtg cgatcccaat tgccattgat caagcaaaaa aatggtatga agatgctagt
    22621 gaatcagaaa aacgaacttt cgaaaaagaa aaaaatccaa gcaagacgga tgaacacgat
    22681 acgaatcctc gtgctggaaa actgcttgat tcagatgtga tcgtagaata tgaggaagaa
    22741 caatggatcg tgaaatctaa aggggcaaaa aaggcaagca accattttga tacaaaaaaa
    22801 gaagcaatcg aaaaaggaaa gcaagtagca caaaacaaag aatcaacttt gttcatttat
    22861 aaaaaagatg ggacaaaaga aaaagaaatc gattattgaa catatgtaaa ggggttgtga
    22921 cgaaaatcgt gtcacaaccc ccttatgttc gaaacaatgg tgttcctctg ccaactccga
    22981 accataagtc ataatatcta taaaacggga agagctgttt tttgaaattg tttcttatca
    23041 ctcagtgtta aacggtagga gaaaacctct tttttattga tatttgattt tcatcaaaca
    23101 gtcacatagt cgattgcttc tgcttgcgga atcgtttcat ctacaaagta gactttatac
    23161 catgtcaaga aactgaagat tgtccagatt tttctttgct cttctttacg tccttcgtga
    23221 tggtcatcta gcaacttcat gattttttct tgatcaaaaa attcttttgc aaaatctgct
    23281 tcgaacaatg ctttgacttg ttcgtagccg tgttcttctt tcaaccaagc tttgattggc
    23341 acagggaatc ctaatttcac acgattcgac catttttccg gaagatgttt gttcgcagct
    23401 tgtctgaaaa tatcttttgt gttgttttga ttcaataaaa acttacttgg tatttgttga
    23461 gccaatttca tgacttcgat atccaataaa ggtactcgga cttccaaaga acttgccata
    23521 gaaagtttat ctgcctttaa caagatatct tttggcatcc attgatgaag atcgacatat
    23581 tgcatcttat tgacttcatc tttgattcct tctgttttct cgtaatgaac agtcatgatt
    23641 tcatccacag atggtgctgt ttgatatttt ggtgttaaca cttctgatgc ttctgattct
    23701 tcgaacactc gagcatgacc gataaaatat tcttttgcag gagcaagtga ttcatataaa
    23761 tggatccgtc catggaaatt tttcattttt ccgattttac gtcctaaatt atagcgtgtt
    23821 ccttttggta attttttcaa tccttgagca atcacacgga tgaattttga attcgtatgg
    23881 aatccatacg tttggtatcc cgcaaacagt tcatccgccc cttctccaga ttggactacc
    23941 cgcacacttt gtgaagcaag atttgctaaa aagtacaaag gtacgcaaga aggatttgaa
    24001 tcaggttcat ctaagtgata ctggatcaaa gggaatgctt tgaacgacat gtctccgtcg
    24061 atcactgctg ctgtattatc taagtccaat agttcggtta gttttctggc ttcaatcgtt
    24121 tcattatagg ttttatcatc aaacccgatt gagaaagaat gatctggttt caatacagag
    24181 gttacataac tggaatcaac cccgctggat aagaaagaac caacttctac atcactgacc
    24241 gtatgtgctt caatagaagc ttgaacggtt tcgtcgattt tttcgatcca ttcttgtcgg
    24301 gaatgcgttt cttttgtttc aaaatctgca tcccaatatt gctgaatgtc tatttttcca
    24361 tctttatacg tataataatg gccttcaggc aaacgataga catctttgaa gaatgtttcg
    24421 ccgtttaatg gagaatattg gaaagtcata taaggtttca acgcttcttt gttcaattct
    24481 ttgttaaaat caggatgagg cagaaaactt ttgatttctg aaccaaacat aaatgttccg
    24541 ttcatttctg cataataata tggtttgatc ccaaagtggt ctcttgcacc gaataactca
    24601 ttcttttcat tatcccaaat agcaaaagca aacattccgc ggatcttttg caataattct
    24661 gttccccatt cttcgtaacc atgcaaaagg acttctgtat ctgcatgtgt ttgaaaaacg
    24721 tggccagctg caatcaattc ttctctcaaa ggctggtaat tatagatttc gccattaaaa
    24781 ataatgatct ttgtccgatc ttcattgtaa ataggctgag taccgccctc taagtcaata
    24841 atacttaatc ttctgaatcc taaagcaaca tgtttatcga tatattctcc tgaactatta
    24901 ggtccacggt gaacgattcg atccatcatt gtattaataa ttgttttttt gttgtccttg
    24961 tcgttaacaa aacctacaat accgcacatt taactttcac atcctaatat aaaattactg
    25021 tttatttcat tcatatgcat cttatcatag aataaatagc ggacgaatat tttctctctt
    25081 acaatttcgt cacgtgaaaa caaaagatga aagtttctgt ttttacagaa aataaagtcc
    25141 caatatctaa tttaccatgt tttctttttt gaggctacct tattctcttc gtgttaaaaa
    25201 aatattagtg gatgctattt ccaaaaaaac cagcaaaaaa agacacgacc taaagatcgt
    25261 gtctaattat gactgtatca gaaaatatga taccaaacgg atctattcat taattaattg
    25321 acatagttta tctgttgctc ttttatgact ggataactga ccaattcatg acgatccaag
    25381 tcttctttat tcatatttac agcagtaatt tgactgtctt catacgtacg ataataataa
    25441 atccctttat caacgttaca gcaagaagaa taaatcgtat attcgtattt tctttctcca
    25501 gtatcgcata ctcctttttg ttgctcgact gagcctagta tatgaaaaaa ttgactgata
    25561 ctttcagatt ctgaatcacc tgatgcagca ttcattttag taaatgtggc ttttacaaat
    25621 cgagaaacag aagagagatc tccaggtaag cccaatcctc ccatcccacg actataaaca
    25681 ttcaagctga tctggtttga aaaatgattt tctggtgttc catttgatag cgagcgataa
    25741 ttgttcagat taaataattg ataatcaaat ggcggattat ttgtcaacac accgacagga
    25801 ttatcatata aatgaagtcc atctttcata ctttcaatta ctatcgattt ttctttatca
    25861 gctaataacc agtgtaaagg tgacaagggt agtttttcac taaaatcgat attgactaga
    25921 ttgatagtag ccaataattc tttagcttcg tctatggttg agcattgccc tagtatccat
    25981 ggaataaact caaatggtgc aacgttatct tttccttctt gtaattcttt ataatcagca
    26041 ttgccaggaa aattcagtcc tgccatactc aacccttttt catttgtagc ctcataatag
    26101 agtggatagt tggatacccc agctgctatt cctatcattg cataatgttt atctaaattt
    26161 tttacctttc taaaatcgaa acgataattt cttggagtaa tagtgaccac ttcattataa
    26221 gacatctcat aatcaaaatt ccttccaaaa taatggtctt tcgttgcata agtgattgcg
    26281 gtacacatcg tttcccgtcc taaaacaaat cgtttttaca cttttatctt acatctagta
    26341 ttttttttat caaaaaaagg ccaaagaaga ttgatttact agcatttata aaaaatagta
    26401 ctcaggggga atcaaaaaat att
//
LOCUS       DARPZF010000035        26027 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.036, whole genome shotgun sequence.
ACCESSION   DARPZF010000035 DARPZF010000000
VERSION     DARPZF010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.036"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(43..681)
                     /gene="plsY"
                     /locus_tag="SLE65_001829"
     CDS             complement(43..681)
                     /gene="plsY"
                     /locus_tag="SLE65_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEI8449123.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            808..1242
                     /locus_tag="SLE65_001830"
     CDS             808..1242
                     /locus_tag="SLE65_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEI8449124.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            1408..3453
                     /gene="parE"
                     /locus_tag="SLE65_001831"
     CDS             1408..3453
                     /gene="parE"
                     /locus_tag="SLE65_001831"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEI8449125.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            3465..5915
                     /gene="parC"
                     /locus_tag="SLE65_001832"
     CDS             3465..5915
                     /gene="parC"
                     /locus_tag="SLE65_001832"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEI8449126.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDRSIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            6192..8423
                     /gene="pflB"
                     /locus_tag="SLE65_001833"
     CDS             6192..8423
                     /gene="pflB"
                     /locus_tag="SLE65_001833"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEI8449127.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            8667..9428
                     /gene="pflA"
                     /locus_tag="SLE65_001834"
     CDS             8667..9428
                     /gene="pflA"
                     /locus_tag="SLE65_001834"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEI8449128.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            9513..10439
                     /locus_tag="SLE65_001835"
     CDS             9513..10439
                     /locus_tag="SLE65_001835"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEI8449129.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            10621..11514
                     /locus_tag="SLE65_001836"
     CDS             10621..11514
                     /locus_tag="SLE65_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEI8449130.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            11648..11773
                     /locus_tag="SLE65_001837"
     CDS             11648..11773
                     /locus_tag="SLE65_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8449131.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(11907..12539)
                     /locus_tag="SLE65_001838"
     CDS             complement(11907..12539)
                     /locus_tag="SLE65_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449132.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(12687..13229)
                     /locus_tag="SLE65_001839"
     CDS             complement(12687..13229)
                     /locus_tag="SLE65_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HEI8449133.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            13364..13753
                     /locus_tag="SLE65_001840"
     CDS             13364..13753
                     /locus_tag="SLE65_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449134.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            13757..14521
                     /locus_tag="SLE65_001841"
     CDS             13757..14521
                     /locus_tag="SLE65_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEI8449135.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQAGEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            14650..15597
                     /locus_tag="SLE65_001842"
     CDS             14650..15597
                     /locus_tag="SLE65_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8449136.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            15727..16467
                     /locus_tag="SLE65_001843"
     CDS             15727..16467
                     /locus_tag="SLE65_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449137.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(16758..17426)
                     /locus_tag="SLE65_001844"
     CDS             complement(16758..17426)
                     /locus_tag="SLE65_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEI8449138.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            17560..17847
                     /locus_tag="SLE65_001845"
     CDS             17560..17847
                     /locus_tag="SLE65_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449139.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            18263..19801
                     /locus_tag="SLE65_001846"
     CDS             18263..19801
                     /locus_tag="SLE65_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEI8449140.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            19798..20763
                     /locus_tag="SLE65_001847"
     CDS             19798..20763
                     /locus_tag="SLE65_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8449141.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            20750..22072
                     /locus_tag="SLE65_001848"
     CDS             20750..22072
                     /locus_tag="SLE65_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEI8449142.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      22135..22239
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            22313..23056
                     /locus_tag="SLE65_001849"
     CDS             22313..23056
                     /locus_tag="SLE65_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8449143.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            23071..24063
                     /locus_tag="SLE65_001850"
     CDS             23071..24063
                     /locus_tag="SLE65_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEI8449144.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            24075..24812
                     /locus_tag="SLE65_001851"
     CDS             24075..24812
                     /locus_tag="SLE65_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8449145.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            24802..25524
                     /locus_tag="SLE65_001852"
     CDS             24802..25524
                     /locus_tag="SLE65_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEI8449146.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(25608..>26027)
                     /locus_tag="SLE65_001853"
     CDS             complement(25608..>26027)
                     /locus_tag="SLE65_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HEI8449147.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         8953 a         4426 c         5429 g         7219 t
ORIGIN      
        1 atttgtcaca ctcccgtttt atctctttgg aatgaaaaag tatcaggatt ttttcttgct
       61 gctattcaaa ccaaacggga ttcgactttc agtatggttt ctgatacgct tgatattgtc
      121 tttatgccga taaaagataa aggaagaaac taaaaaggca atgatcgtca gtaaccaatt
      181 gggcttagcc aaaatcacag gagctacata aggaaggacg atcgtagata aagtgatcaa
      241 tactgcactg atcatactgc tcaaactcac catacttgta caaaataaac taacgataaa
      301 gatgatacaa gaataaacaa aaaatacagg attaaatcct aaaagcattc ctgcacttgt
      361 cgcaacagct tttcctcctt tgaacccagc aaaaatcgga aatgtatggc caagaatggc
      421 gcatacccca aaccaaagag ggttaatccc agaaaggtgg aagatcatcg gcaaacaagt
      481 agccaatgta ccttttaaaa tatccataag caggacaaca atcccggctg ttttgcctaa
      541 tacacgaaat gtattggtcg ttccagtatt accgctcccg tgttgtcgga tatctttttt
      601 gaaaaacaat ttgccaatcc agacaccgga aggaatagaa cctaaaagat atgctaaaat
      661 aagtaataag atcaatttca ttttttaccc tctttcaagt tgaaaactat cctttatttt
      721 agcatgaata ggtaacagga acaattgaaa aaatgaaaga tacaagtata atagatggaa
      781 taaaaagaaa agcaaggggt ggcagaaatg tctgtaaaaa atccaacaca agaaacgatt
      841 ttcaactatt tggaagaagc aaaaaatatt gccgtcgtag gcttgagcaa taaaccagaa
      901 cgaacaagtt acatggttgc acaggtattg caagacaatg gatataaaat cataccagta
      961 aatccattat tggctggtga agaaattcta ggcgagaaag tctatgcgaa tttgacagaa
     1021 atcgatgatc caatcgatat cgtagatgta tttagacgga gtgaattttt acctgaaata
     1081 gcaggtgatt ttttgaaaac tgatgctaaa gtgttctggg cacaattagg gattgaaaac
     1141 aaagaagcag ctgagatgct aagaaaagca ggacgtacag atatcgtaat ggatcgttgt
     1201 attaagattg aacttggtaa gttgaaagaa aaccaaaaat aaaaatgacc acaaagaaga
     1261 gatgatcgat agaggggaat gtcgaaaaag cggttaggag ataattaaaa ttgatttctc
     1321 gtctaccctc ttttttttca cgaccttttc tagtatgata atcgtggtgc ggttttgccg
     1381 caaagtatta ttgaaggagc gtttgccttg gcaaaaaaag taaacaacga atacaatgac
     1441 tcgtccatcc aagtattgga aggattagag gcagttagaa aaagaccagg gatgtacatt
     1501 ggatccactg acagccgagg cttgcatcat ttagtctatg aaatcgtcga taatgcagtt
     1561 gacgaagcat tatcaggtta tggcagtgag attgatgtga ccatccatga agacaatagt
     1621 ataactgttg cagatagcgg acgtgggatg cctgtaggaa tgcatgcttc cggaatacca
     1681 acagttgaag tgatttttac tgtgctgcat gctggcggaa agtttggtca aggagggtac
     1741 aaaacttctg gtggactgca cggtgtagga gccagtgtgg taaatgcctt atcgaaatgg
     1801 ctaattgtaa cgatcgttag agatggcgta gagtatcagc agaaatttaa aaacggcggt
     1861 aaacctgacg gtactttgaa aaagatagga aaaacaaaaa aagcaaacgg gacgactgtc
     1921 cattttttac cagatgatac aatattcagt acaacgaaat tttcatatga aattttagcc
     1981 gaacggttaa gagaatctgc ctttcttcta aaaggcgtta aaatctctct ttctgatctt
     2041 cgtggagaag aaccagtcaa ggaaattttt cattacgaag aaggaatcaa agaatttgtt
     2101 gattatctga atgaagaaaa agatacattg acaccagttg tttatttttc aggagaaaaa
     2161 gaaggtatcg aagtagaggt cgcttatcaa tacaatgacg gttattcaga aaatgtttta
     2221 tcttttgtca ataacgttcg gacaaaagat gggggaaccc atgaagctgg tatgaaagcg
     2281 gcgatgacga aatcttataa tgaatatgcg agaaaagttg gtttgctgaa agaacgggac
     2341 aagaatctgg aaggtagtga tttcagagaa gggttagctg ctgtactttc tatccgtgta
     2401 cctgaaaatc ttctgcaatt tgaagggcaa acaaaagaaa aacttggtac gccagttgct
     2461 cgtaccgtag tagataacgt catcagtgaa caaatgggct tttatttgca ggaaaatagc
     2521 gaaatgagcc agatgttggt ccgtaaagca atcaaagcca gagaagcgag agaagcagca
     2581 cgtaaagcca gagaagaaag ccgaaatggg aagaagcgta aaaaaggcga atctcttctt
     2641 tcaggaaaat tgacacccgc acaatcccga aaccctaaga aaaatgaatt gtatttagtc
     2701 gaaggggatt ctgctggcgg atctgctaaa caaggaagag acagaaagtt ccaagcaatt
     2761 ctacctttac gaggaaaagt catcaatacc gaaaaagcta aaatgcaaga tatcttgaaa
     2821 aatgaagaaa tcaatacgat gatctatacg attggtgcag gagtcggtcc tgagttttct
     2881 atcgaagact gtaattacga caaagtaatc atcatgaccg atgcggatac agacggcgcc
     2941 catattcaag tattactgct tactttcttt tatcgttata tgaaaccgct gattgaagct
     3001 gggaaagtat atatcgcgtt accgccttta tataaagtat ccaaaggaca aggaaagaag
     3061 caagtcattg aatatgcgtg gacagatgac gaattggcag caatgattaa aaaagtcggc
     3121 aaaggatata tgctgcagcg atataaagga cttggagaga tgaatgcgga acaattgtgg
     3181 gaaacaacga tggatccgac ttcccgtacg ttgatccgcg tccgtatcga tgatgctgcg
     3241 caagctgaac gtcgagtaac cacactgatg ggtgacaaag tagaacctcg aagaaaatgg
     3301 atcgaaaatc acgtgcaatt tacgctcgaa gaagatggca gtatcttaga taaaaaagag
     3361 gatactgaaa tctctccttc agtttctaat gatttattag atgaagaacg agcagataaa
     3421 aatgaaaaca atcagttatt tgaagtagaa taggaggtca cctgatggaa aatcgacaag
     3481 aagtacaaga attaacttta gaagaagtga tgggtgaccg cttcggacgt tattccaaat
     3541 atattatcca agaacgtgca ctgcctgata tccgtgatgg attgaagcca gtgcaacgcc
     3601 ggatattatt tgccatgaac aaagatggca atacgtatga caaaggattc cgtaaatcag
     3661 caaaatctgt cggaaatatc atggggaatt atcatcctca tggtgaccgc agtatttatg
     3721 aagcgatggt ccgcatgagc caagactgga agttgcggga agtactgatc gaaatgcacg
     3781 ggaataacgg gagtatggac ggtgatccac ctgctgcgat gcgttatact gaagccagat
     3841 tatccaagtt aagtggagag atgctagcag atatcgagaa agaaacagtc gatctcgtgt
     3901 ggaattttga tgatacagaa aaagaaccaa cagtccttcc agctcgatac ccaaaccttc
     3961 tcgtcaatgg atcgacaggt atatctgctg gatatgcaac agaaatcccg actcataact
     4021 tagctgaagt gatcgatggc acaatctata tgatcgatca tccacaagcg agccttgaaa
     4081 aattgatgga atatattcct ggacctgact ttccaacagg agggatcttg caaggaaaag
     4141 atgaaatcaa aaaagcttat gaaacaggac gaggaaaagt tattcttcgt tcgaaaacaa
     4201 agatagaggc aatgaagggt aataaacagc aaatcgtgat cacagaaatc ccatatgaag
     4261 taaataaagc gaccttggtg aaaaaaatgg atgagatccg tttgaataag aaaatcgatg
     4321 gaatagctga agtacgagat gaaagtgata gaacaggtct gcaaattgtc gtcgaattga
     4381 aaaaagacgc caatgctcaa ggaattttga attatttgtt caaaaacact gagctacaga
     4441 tcaattacaa tttcaatatg gtcgctatcg accatatgac tccgcatcaa gttggactga
     4501 aagacatttt aagaagttat atcgagcatc gaaagcaagt cataacaaaa cgtagtcaat
     4561 tcgatttagc caaagctcaa aaaagacagc atatcgtaga aggattgatg aaagctttat
     4621 cgattctgga tgaagtaatc gcaacgattc gtgaaagtaa agacaaaaaa gacgccaaaa
     4681 agaatttagt cgacgtcttt caatttacag aagaacaagc agaagcaatt gtcacattgc
     4741 aattataccg tttgacgaac acggatatca cagagcttca aaaggaatcc gaaagcttga
     4801 ttgcgcaaat cacagagttg aataaaatcc tttcaaatga caaagagctt ttctctgtta
     4861 tgaaaaaaga attgcgagaa gtgaaaaaaa attattcttc cgctcgtcta acgacaatcg
     4921 aagacgaaat cgaagaaatc aaaattgata cgcaagtctt agtggcacaa gaagacgtaa
     4981 ttgtcagtgt gacgcgagaa ggctatgtga agcgaacaag ccttcgttct tatagtgctt
     5041 ccaaaccaga agaaatcggg atgcgagaag gcgactactt gctatactca ggtgaattga
     5101 gtacattgga ccatgttctt ctgatcacaa ataaagcaaa tgtgatctac cgccctgtcc
     5161 atgaactacc cgatttgaaa tggaaagatg ctggtgagca catttctcaa acaatctcca
     5221 atctgtctgt agacgaatcg attttagctg ttttcccata tcaaaaaatt caagcagaga
     5281 aaacatttgt attcatcagc aagaatggat tgatcaagca aacacgaatg acagagttcg
     5341 aaccatggcg cacctataag agccgtccgc tcagctgtat gaagctaaag gcggaagaag
     5401 atgaactgat tgctgtgtat ctgaaagaag atcagccagg cttagatgtt ttcttagtaa
     5461 cgcatcaagg aatgggtttg cgctatcctt taacagatgt tcccgttgtt ggagcaaagg
     5521 cagctggagt gaagtctatg aatttgaaag atggagatag gattatcaac gggctgcttg
     5581 tgttagcaga aggtgatacg ccgatcgtaa tcgttactca gcgaggagct gttaaacgca
     5641 tgcttgctca agaaatcagc caaacttcac gtgcgaagcg gggagtgacg gtcatgcgtg
     5701 agctgaaaaa aaatccgcac cgtattatct atatgtcgga aggaagatca aaagaaataa
     5761 ccttgatgaa tcaaaaaggg cagcagttaa cgattgaccc aactgatttc cctataggtg
     5821 atcgaacatc gaatggatca tttgcgatgg atgagaaaaa aggtggagaa gtcatcgaag
     5881 ttatcgatgc tcctgagatt ttcatcgagt cgtaactgtt gtagtatttt aatgaagaga
     5941 cgccatctgt attaatacag gtggcgtctc tttttcattc atttttaata aatccttata
     6001 cgtttgcaaa aaaagatgaa agtgttcaca atgcttaaat gttggtatgt caacgttgat
     6061 ttaaatatat gtaaataaaa cataaaaatt gttaaataaa aaacaagaaa acccttgcaa
     6121 agatagggtg ctgtgttata ctaatcacgt aaaaactgtt acataaaaca gaaatttagg
     6181 aggtccatac aatggagcaa tggaatggat ttaaaggtac caaatggaaa gaaggcgtag
     6241 acactagaga ctttattcaa aataactaca ctgaatatcg cggtgatgac agctttttgg
     6301 aaggcccaac agaagcaaca gaaaaattat gggatgaatt gcaaaagtta aatgatatcc
     6361 aattcgagcg taacggtgtc tatgatatgg acacagaaat cgtatcaact attacttcac
     6421 acgatgcagg ctatttggat aaagatttgg aaaaaatcgt cggtctacag acagacaaac
     6481 ctttgaaaca agcattcatg ccgttcggcg gaatcaatat ggctaacaat gcgctaaaaa
     6541 gcaatggcta tacaccaaac gatgaattga cacatatttt cactgactgg cgcaaaacac
     6601 ataatcaagg tgtatttgac gcttatactg ctgaaatgcg tgctgctcgt aaaaacaaaa
     6661 tcattacagg gcttccagac gcttacggtc gcggacgtat catcggtgac tatcgtcgtg
     6721 tggcattgta tggaatcgac tatttgatgg aacaaaagaa aaaagatcat gatatgactg
     6781 gttatcatac aatgagtgaa gaagtgattc gtttacgtga agaaatcact gaacaatatc
     6841 gtgcattagc gcaaatgaaa gaaatggctg cgaaatatgg ctatgatatt tctaaaccag
     6901 ctgcaaatgc aaaagaagct gtccaatggc tatacttcgg atatttagca gcaatcaaat
     6961 cacaaaatgg tgctgcgatg tcaatcggac gtatctcagc attccttgat atctatatcc
     7021 aacgtgattt ggataatgga gtaatcacag aaaaagaagc acaagaattg atcgaccact
     7081 tagtaatgaa attacgtatg gtcaaattcg cgcgtacacc tgaatataac caattattct
     7141 caggattccc tatctgggct actttatcca ttgcaggtat gggattagat ggtcgttcat
     7201 tagttacaaa gaatgatttc cgtctgcttc atacattaac aaatatggga ccttcaccag
     7261 aaccaaactt gactgttttg tattctgaac accttccaga aggattcaga acatatgcta
     7321 gcagaatcgc tatcgaaagt tcttcgattc aattcgaaaa tgataatcag cttcgtgaac
     7381 aatggggttc tgatgattgt gcgattgctt gctgtgtatc aggaacagtt gtcggaaaag
     7441 acatgcaatt ctttggcgct cgtgctaact tggctaaaac actattatat gccatcaatg
     7501 gcggagtcga tgaagtgact ggcgcccaag ttggaccaga atatcgtcca atcacatcag
     7561 aaatactaga ctttgaagaa gtgaaacata acttcatgaa tatgatggat tggttagcag
     7621 aactatatgt caatacgttg aacatcattc attatatgca tgataaatat tcttatgaag
     7681 cagctcagct ggctttgatg gattctgact tgcaacgcac atttgctaca ggtattgctg
     7741 ggatctctca tgcggcagac agcttgtcag cgatcaaata tgcaaaagta aaagcaatcc
     7801 gtaatgaaaa aggaatagca gttgattttg aagtggatgg cgacttccct aaatacggaa
     7861 atgatgatga ccgtgcagat gaattagttt catggatctt ggaatacttc atgggacaaa
     7921 tcaaacgtca taaaacttac cgcaactcaa aaccaacaac ttcattattg acgattactt
     7981 caaatgttgt ttacggtaaa aatacaggaa atactcctga tggccgtgaa gctggaaaac
     8041 cacttgcgcc aggagcaaat ccaagttaca atgcggaaca aagtgggtta ttagctagcc
     8101 tgaactcaac agctaaaatg aattacggct gtgcattgga tggaatttca aatacccaaa
     8161 caatcaatcc ttcaggtctt ggaaaagaac aagatacaag aatcgaaaac ttgcgtaatg
     8221 tcttagatgg atacttctca aaaggagctt atcatttgaa tgtcaatgta ttcagtaatg
     8281 atttattgcg tgatgcaatg gaaaatccaa tgaaatatcc gaacttgacg atccgggtat
     8341 ctggttatgc agttaaattc cgtgacttga caagagaaca acaattagat gtcttgatga
     8401 gaacttcaca cgacagaatg taaaaagttc gtgaaaaaag tttttcgact tagcgtcgaa
     8461 aggacgttga atagccatcg catcaaaatc gaataatcag tatgcttatt tgaaagaaac
     8521 gatttacagg ggcaggactt gtatgttccg tccctgtaaa ttttacacat aacgaagcgg
     8581 caattgcgaa aaattttgtt cagaaagctt cgcttcgaca gctaacttgt acttaaaatg
     8641 aaatcaaaga aaagatgtga acttaaatgg aagaaaaaac aatcggctat gttcattcta
     8701 tcgaaacttt cggttcagta gacggacctg gactgcgctt tgtcgtgttt atgcaaggat
     8761 gccgcatgcg ttgccaattt tgtcacaatc cagatacttg gaatattggc ggagggaaag
     8821 aatacacagc agatgaactt ttagataaag cagaacgctt cagaccttac tggggagata
     8881 aaggtggtat tactgttagt ggtggagaac ctctattgca gatcgatttt ttgatcgaac
     8941 tatttaaaaa agcaaaagag cggaagatgc atactacatt ggatacatgc ggaaaacctt
     9001 ttacgtatga agaacctttc ttttcacgtt ttcaagaatt gatgaagtat acagatttac
     9061 tgttatttga catcaaacac atcgataatg aagagcataa aaaactaacg cattgggaca
     9121 atgaaaatat tttagaaatg gctcaatatt tgtcaaaaat caacaaaccg gtttggattc
     9181 gccatgtact agttcctgag cgaagtgatt atgatgaata tttgatccga ctagacaact
     9241 ttattcaaac cttgtcaaat gtagacagag tagagattct tccttatcat acgatgggaa
     9301 aatacaagtg ggaaacactt ggtttgaaat atccattaga agggatcgaa ccacctacaa
     9361 aagaacgtgt cgaaaatgct aaacgattgc ttcatacaga agagtataca aaatatttaa
     9421 cgcgataggt cgcatcggaa agaagataag tattgcttct ttccgttttt ttgctattat
     9481 taaataggag aaatcacaaa ggagcgaatg acatgtcaaa aattttagtt tttggtcacc
     9541 aaaatccaga tacagatgca atcggggcag ccattgcgtt ttcacacttg caaaatgaat
     9601 taggtaaaga aacagaagca gttgctctag gtacacctaa tgaagaaaca caatacgcat
     9661 tagaccactt tcagctatct gcaccacgag tagtagagtc agctaaagca gaaaatgcag
     9721 atgtcatgct tgtggatcat aatgaattcc aacaaagtat ttcagatatc agcgaagtaa
     9781 atattttagc tgtagtagac caccatcgta ttgcaaactt tgaaacagct aatccattgt
     9841 actatcgtgc agaaccagtt ggatgtacaa gtacgattat tttaaaacta tataaagaaa
     9901 accaagtaac aattcctaaa gaaatcgcag gaatcatgct ctcagctatc atttcagata
     9961 cattgttgtt caaatcacca acatgtacgc ctgaagatga agcagctgca aaagaacttg
    10021 cagcaatcgc tgaagtcgat ctaaacactt atggacttga aatgttgaaa gcaggaacaa
    10081 atctaagtga taaatcagct gcggttcttc ttgatttgga tgcaaaaagt ttcccaatgg
    10141 gcagttccaa cgttcgtatc gctcaagtca atacagtgga ccttaatgaa gtgatggatc
    10201 gacaagcaga gctagaagca gcaatggaag atgaaatgaa agcaaatggc tacgatctgt
    10261 tcgtattagt tgtcacaaac atcttagaca gtgattcaga attacttgtt gctggtaaag
    10321 gaaaagaaaa agtagaagaa gctttccaaa caactttgac caacaaccgt gctttgctta
    10381 aaggtgtcgt ttcacgtaaa aaacaagtcg tacctcaatt gacggctgta tttagctaat
    10441 caaatggtag tatgaagcat tcaaaatgaa tggataagcg attgatataa aaagaaacat
    10501 agaacatact aaaggccgaa gaaatggagg agaataacag tcaattatga ctcttgttct
    10561 tcctcctttt tacgtaaaag ccttttaagt aaaataaaac ggatagaaaa gagaacatat
    10621 atgaactatt attcaaaaaa taaggaaaac ttttatcaaa aactgaccga tgatccgctt
    10681 ttttcttcat tgaccgatta tctatatgaa catcgagaac aagaaacgat tctaagagaa
    10741 ttgaaaaaag aattttcgca aaataaattt tcccattttc ttgatttatt gatcgatgca
    10801 ggattaatca agagggaaga acgaagatat catttgaact ttccaatatt tgatcctaaa
    10861 gattacttgc aacaagccac ttcggctgct gaaaccatag ctgaacaatt gaagagactc
    10921 tctgttgatg aacaaaaatt agcgatggga gaagttattt gggcgtattg tttcgaagat
    10981 gaacggaaag aagcgtattt ttatggagta agaaacagcc gagagacaga attgctgagg
    11041 acaactgcag gaaatgagaa gtaccgtttt atcacacttt cctctataga acacttcccg
    11101 cttactttgg ctaattactt ttttgtacag aagaatcagc ttcctgtaac gaaggcattc
    11161 aaagaattag ccgaacttat tggagacgta aatgaatcgt acttttttga tcaaatagaa
    11221 gttatcgttg acaggatacg taagaataaa tataaaaatc gccggcctag tattttccat
    11281 cagtctctac ttgtgacgaa tactataaag gaagaagaat cattcacatt agaattacct
    11341 attgtcgaaa aaaacaattt tgagattgaa ttaccaacat tggatccttc attgacaatg
    11401 gaggaaatgg cctttcttaa acgacaaatc ttttctgagc tgagcaagaa atttataccg
    11461 catgcatttt cttatatcaa agaatatgga acagttttag tgagtaaaac ctaagagagc
    11521 agtaagcaaa aattatactg actcttgcag gaggagcctt tctcttcctt tatggttaaa
    11581 agaattattt gagtattttg cctatctacc acctattaga ttcactacat ggtctggaaa
    11641 caaaggaatg caaaaaaatg gtgagaaatg tggaatgaca aaggaagtag tgataagaaa
    11701 agttagattt ttaaataatc aatattatga ttcagtcaag tatggcattt tatgggaaga
    11761 actagctgat tagattagga agtccatttg ataatccaga atcactaaga aacgaatggc
    11821 gagtcattaa taatttatcc aatcttgggt tattctttta gattgaagtg tttaaaacta
    11881 aaaaagcatt tatgaagtcg taatagtcag gcttcaaaat gctttttatt ttgtttgttt
    11941 tttctttgcc acataaatac acctagactg acgatgaaga gcatatccaa cagatttcct
    12001 gcgacttgga tcgtcgaagg gttggtcagt ggcattaaag caaggacaaa aaaggaaaac
    12061 aagctgtaaa taaaacaggt gacaggaact aatcgaaaga agagcggaca tttcaattgg
    12121 ctaaaaatga gtgaaaaaat aaaataagta aaaatggata aaatcacgac taaaccattc
    12181 atgataaaga agaaaagcgt attgtgatta aacgaataaa aaagaattgc taaaaaagaa
    12241 aacgttttaa atgcaatcaa tacgcttgaa gcttcgttta acgtaccagg atgtcgatga
    12301 aaaaaatagg caccgaaata aacagaaaac agtaagccgc aaagagaaga caaaatcaaa
    12361 aaaaacggat tttcttcggc ttctgtgata tcagaatgat ccaaaagcaa ccagcctaat
    12421 gcactagaag gcgcatgtga ggtcttaagg tatgaataac atagaaaaaa taagatcgtc
    12481 aaagttgcaa aaaaagagcc taaatgtaaa aaattagtgg ttctacgttg aatttccata
    12541 atatctccaa attaaattga taagtatata aagtataata acaaattgat gagtatatgt
    12601 cgatgttttt taatcaaaat aataaataaa aactgtctaa catttaaaat ttaatttaga
    12661 tattagacag tttttaagtt tgtgagttat tttccttgtc gttttctcac ttttttagtc
    12721 cagaaaccac ctgaaatata ttttggctca taagaaatga taaaagcacg ctcttcgatt
    12781 tctttgatca ggcgatacag ttcacgttcg ctttttctag gagaaagtat ttcgagaact
    12841 agccgctcac cttccagccc cattgcagaa gtctgtgtca caccataacc gtgttctctc
    12901 agtatacccg gcaaactttt atcttctgcg ctatttgctg gcaaaatcgt tgtgaccatg
    12961 atgtatccta atgccaattt gtcttcaatc aaaattccga cactgatacc tactgcgtaa
    13021 cctaacgcat agacaaataa attcagtgga ttatctaaac gatctaaaac aagggataag
    13081 ccgacgatat aaatcgtgat ctcgaccata ctgacaagtg gagcaatcag tcgatagcct
    13141 ttcattgtca acatgaaacg taacgtgttc agagtgatat aagcaaaatt aatgaggaag
    13201 atcatcccca acatttttgg atcaatcatt tgtaaaactc ctttcattta tataacaaca
    13261 atatcaaaaa aaatcgtaag tgaagaaaaa ttgaaacttt atacatacaa aaaaatgata
    13321 aaatgattat aatagaatta taaagatagg ttaggtgatt aaaatgaaaa cggtcaatcg
    13381 tgtgttttgt gccagccacg tgctaagtct ccttctcagt atatacttag gtgtctattc
    13441 gattcaacag ccaattgagg tagagaacat tgtttttcag atgtcgctga cagatggttt
    13501 aattttaagc gtttttttct ttttgatact gtttattggt aatattttcg gtagcgttgc
    13561 cagttttttg aatttttcta tttatccact cctttcgcta gcattaggag tggtgggact
    13621 ttgttctctg tgcttatttc ccgagccatt cagtcctgca tttatattat ttggtacact
    13681 gaacctgttc cagacaactg ttggagcatg gttgctatgg cgatcaggaa atttaatgaa
    13741 aataggtgag taacaattga atccaattat attgaaacgt tctgtccatc atattccagt
    13801 gttagaagtt gttctgaaag aattaagaga ggaacgtatt cccgttgtca tctattatca
    13861 cggatggcag acaagtaagg agttagtttt gacgcaagga agaaaaattg cgcagcaggg
    13921 cattcgtgtg atcctgccag atgcgatgaa tcatggggag cgcaaacagc cggtttcttc
    13981 tattccatcc tatacatttt gggatagtat ctacggaaat ctgtttgaat ttgacacact
    14041 tatcaagcat ttagaaaaaa gaggtcttct acatgatcag cttgcagttg gcggggtttc
    14101 gatgggggga atgacaacat gcgccttgtt ggctaaacat cctcatatag tagcgggcgt
    14161 gtgtttgatg ggttcccctg cacctttgga atatggaaaa gaaatcgtaa ggcgcgcatc
    14221 ggaatataat tatgtcgtac caaaagacta ttttgatttg atttcatggg ttaagagcta
    14281 tgatttgtca ttgcagccgg aaaagttagc tggacgtcct ctgttctttt ggcatggaca
    14341 agctggcgaa aaaatccctt atatacaaac ggaacgattt gtagaaaaaa atcggcataa
    14401 gtcttacgga aaagaaattg tttttcgttc ctcaaaaaca cagcgacata tggtacaaat
    14461 accactaatg gaagaagctt ccactttttt agcaaaaaat ttgataaaaa agtataaata
    14521 attgaaacgg aaaatcactc atgacgatag aggattttcc gttttttatt ttgggctata
    14581 ataaactctg ttaggaaaat ttggtataat tgatagtaag aatgacaaca tgttagaaag
    14641 gaagagagca tgcccacttt agcagatgtt gcaaaacgtg ccaatgtttc aaaaatgacg
    14701 gtctctcgag tcatcaatca tccggaacag gtgactgacg aattgaaaga gttagttttc
    14761 tcagcaatgg ctgaactgga ttaccgtcca aatattgctg caaaagcact tgtcacgaat
    14821 cggtcgcaga tcatcaaatt atttatactg gaagaaatcg acacaactga gccctattac
    14881 atgaatttgc tgatgggaat cgctaaacgg atcggtaaag cgcattattc tctccaatta
    14941 gttacaaatg atgccttcga cgtcggttct tgtgatggat acatcatcac aggtgtcaga
    15001 aaaaaagact tcgattggat cgaccgtttg gaaaaaccag ttgtcttgtt tggggaaaat
    15061 tctgaaggat atgattatgt agacagcgat aatgaatatg gtacagcaaa agcaacgcaa
    15121 tatgccttag aaagagatta tcaaacgatt atttatatcg gtatcgaagt ggacgagcct
    15181 tttgaaattt caagggaaac tggttattta tctgtgatga aggaagttga tcttcctagt
    15241 aaaatcttgc ggtttccaaa tcattcgaca gaagtagaaa gatatatgac agaaaactgg
    15301 gcagatttta cagataaaac ttgttttgta tgtagttcag atcggctagc actaggagca
    15361 gtaagaggga ttataaatgc tggaggacac ttgcccgaag aatttggtgt gattggattt
    15421 gatggggtat ttttagacca aatcagttca cctaaattga caacgatcaa gcaagatatt
    15481 atacgtatgg gtgaagtatg tggagaaatg ttgttaaaaa aaatagaaga aaaaggggcg
    15541 agtcaaggtt atcgtcgttt ttttcctgaa ctagttatca gagagacaac gaattaagtc
    15601 ttattactat atatatattt atgaaattca tcgctatttt cttaaaataa tcagcgcatt
    15661 gctactgaaa acaatgaatc tgtgctatta ttgagaaaag ttccattttt gagaaggatg
    15721 gtttgaatga aagaaatcag acgaaaacat ttccgttttc ctgcgtacga tgatgagtta
    15781 ggcgtaaaat taaccaacga caagaagcga gtattatttg acggacaaga agatcttttg
    15841 actgaacaga atcagtcccc gtttgaacag atgaaagaat ttcatttcac gaacacgaac
    15901 accgagaaaa tccgtcgcaa gcgtcgtgca acaaatggat tgaagtcagc tccgcgtaag
    15961 gaaaatttgg aaaagcataa aggaaaatta ccggattata ccggccatta ccaatcagaa
    16021 atcacatcga caggacgaaa aaaacttttt ggtgattcct ctcgttctgt cagacaaagt
    16081 gaaacaagga cagagtccaa gcatactaca cgaaacgcat ctgttgacac gaaggtgcgg
    16141 gagcgttctt attttgttcc taaatatgta cccgcatcga ttatcccaga ccctagagaa
    16201 agcaaaattt ctgaggatca tttaatcgaa tcgatgaaaa aaacggatga ctcttatctg
    16261 ttgttcgata cagaaccgac gccgtatcaa gaaaaaagaa atggtgagcc gtctgtacga
    16321 acattcaatc gaacaaaaac gttagaggaa acaaagcagt cagaagaaaa aaaatcgaaa
    16381 aaaagccatg gtatcttaga acgctcatta caaggattga tcgatgatca aggaaactct
    16441 ttgggagaaa atagctattt taaataagtg atatacaaat ttatattcgg ctacagttgg
    16501 aaaggaaacg ctgcggcgtt tccttatttt atactctatc cgaaagttta tatcgtatcc
    16561 tcaaattttt ttgagtttaa gcgaattttt tctcccaata agtaagaaaa taatggcaaa
    16621 ataaaaaaac aaactatttt cgcagatcgt ttgcaaaaat agtttatttt tttataaaga
    16681 agattttact gaataatatc attttagttt acataatgat atttctgtaa attaaataaa
    16741 gtagtgaaaa ataagaatca gtgctctaac tgttcaagag gatcaagtgg ttcaaatgtt
    16801 tctgtagtct gttttgcttc caattggggc aaaacagatc caatttccag atacttcact
    16861 ttattcaatg tataagatag aatagaacag ctaagtaatg tatacagaaa atgtgtgaga
    16921 tccaaataaa gcaaggagac aactaaaata ccaaaagtaa tcaagaaaag acttttgcca
    16981 atcttaatat gaaaatattt ttcaatggct tgataaatga tatctgttcc gcctgtgctt
    17041 ccgccgaatc gaaagacgag accgcaacca atgccagaaa gaatacctgt catcaaacta
    17101 ttgatcagta gactatctac agcaaaatgt atatgaaggc tctcccataa atgtaaaaag
    17161 aaaactagcg caaatgttcc gacgatcgtc cggagaaaag cgtgttttcc aaaaagaaac
    17221 aatgagataa gcaataaagg taaattaaaa agcagtgaag tgacagaagg agcgaatcca
    17281 aaaagattat gcaaaagcaa agcaatacca gtaaccccac catctgccag cttagatgga
    17341 atattgattc ctgtcacagc taatccgtag attcctgcgc ctaaaatgat tccgcacaat
    17401 tctgtaaata aatttaattt tttcatttct agcctctttt cttttgaaaa ttttcagcaa
    17461 cttctttatt atactgactt atactcttac ttcaagagga aaatgaaaaa aaattatttt
    17521 tggctgtttc tttttattta tcaaataagg agtggaaaaa tgcgagcagc agacttattg
    17581 acaattctta caaaatcacc caaaaaaaca gagtatcaag gagttttttt ggctcaagaa
    17641 caaaaactgg tgcctgtgac aatggtccag ataaataaag caaatcaatt tatcttttta
    17701 tttgaacacg gcaaagcacc acttgctatg aaagacatct ttcttttttt gatgaagaac
    17761 cgtgagaaag ctgtttatta tcagtcaaaa gaagaactca ttcctcttta tggagtgaaa
    17821 gagatagaaa ataaagtggt gatataagta aaaataagaa aacaagacgt ttatgatgtc
    17881 aaaacaacca ttttttacat ttttggcaaa aaagtgtcat gatacagtat aatattcgtt
    17941 gaacaggcca ataaaggtgt tctcccccac gagatttcta ctttattggc tgtttctttt
    18001 tattaaaata aaagttgtgt gtgtaaaaaa gatatagctg attccaagtg acaatttcgt
    18061 atagattttt atggtattcg tagtgaaaaa acgagaacca aaaagttgat ccgactttgt
    18121 tgcttggatt ctttttttgt cagcatattt agaggtattt ttttcttttt tttgttcgtg
    18181 ctgtaaggtt aaggcaagac aagttagttg ggaaaaagga aagaaatgtt tatacttaaa
    18241 gaataacaga aaggaaggtc gcatgaataa ttttatacaa acattaagtg aaagaaaagg
    18301 cgagttgctg gaagctgcat ttcaacatct gtccatttct ctcatttctt tgctgattgc
    18361 agcactgatt gctattcctt tagcgatttg ggcagccaat cataaaaaaa tggcagaagt
    18421 cttattgcag atcacgggtg tgctccaaac gattccttca cttgccttat taggtttact
    18481 tatcccattt gtagggatcg gaactgttcc agcattgatt gcacttgtta tttacgcttt
    18541 gcttccgatt ttccaaaaca cgtatattgg tctagctgaa attgacccgt ctattgaaga
    18601 agcagcggta gcatttggta tgtccagaat gagacgcttg ctgaaagtag agcttcccat
    18661 cgcattacct gtcattatct caggtatccg aactgcctta gttttaatca tcggtacggc
    18721 tactttggca gcattgatcg gagcaggtgg attagggaca tttattttgt taggtattga
    18781 ccgaaataca cctgttttga cattgattgg tgcgatcagt tctgccttgc ttgcaattat
    18841 attcagcgga ctgattcgct ggttgcagca taagaaacct cgatattcca tcattacttt
    18901 agcagcagtg gtgtgtttat ttggcggcgt ttctttatat cagtctgcct tgtttaaaaa
    18961 tgaaaccatc acgattgctg gaaaattagg agcggaacct gaaatcctga tccaaatgta
    19021 taaagaattg attgaagaca acacaaaaac agaagttgaa ttaaaaccga attttggcaa
    19081 gacgagtttt ttgttcaatg cactggatca aggtcaaatc gatatctatc ctgagttcac
    19141 aggtactgtc ctagaaagct tggtgaaggt acctgaagca atgaaaagtg ctgatttgac
    19201 aaaagaaaaa acatatgacg aagcagaaga attattgaat aagcaattcg atatgacatt
    19261 attaaaacca atggcttacc aaaatacgta tgccttggca gtcaagagat cttttgcgaa
    19321 cgaacatcaa cttaaaaaga tttccgattt ggcagctatc tctgatcaga tcaaagcggg
    19381 attcacactg gaatttattg atcgttcaga tggatataaa ggaatccaag aagcatatgg
    19441 cttgaatttt tcaagtgtac aaagcatgga gccaagtttg cgttaccaag caatcaataa
    19501 tggagatgtc aatattgtgg atgcctattc cacagatagc cagctcaagg agtacgatct
    19561 agtgactcta gaagatgatc gagggttatt cccagcttat caaggcgcac cgctgatgaa
    19621 aaaagatttt gctaaagaac atcctgaaat cgttaaagca ctgaataaat taagcggaaa
    19681 aataacagag gatcaaatga ttgatatgaa ttaccaagtc aatgtcgaaa agaaaaagcc
    19741 gacagaagta gcacgaatct tcctgaaaaa tgaaggatta gtaaaggagg aagatcagtg
    19801 actaaattaa tcgagttcaa acatgtgcaa aaaaagtatg atggaaagta tgtcatcgat
    19861 gacctaaatc tggcaatcaa aaaaggagaa atctttgttt tggttggtcc ttccggtagt
    19921 ggaaaaacaa ctactttgaa aatgatcaat ggattatcta aaccatcagc aggagacatc
    19981 tacttcaaag gaaaatcgtt aaatgaatat aatctgcaga aaatgcggtg gaatatggga
    20041 tatgtgctgc agcaaatcgc tttgttcccg accatgacag tcaagcaaaa tattgaagtc
    20101 atccctgaaa tgttaggttg ggaaaagcag aaaagagcag accgtgtaga tgaacttctt
    20161 caaaaagttg gcttatctcc tgatatttat cgagatcgta tgcctagaga gttgtctgga
    20221 ggagaacagc aacggatcgg gatcatccga gctattgctg caagcccaga tgtgattttg
    20281 atggacgagc catttagcgc attagatccg atttcaagaa actcattaca agaattggtt
    20341 ttgtccttac acgaagaatt gggcacgacc atcgttttcg ttacgcacaa tatggaagaa
    20401 gcaatcaagc taggtgatcg tattgcattt atgaaggatg gagaaattat ccaatgtgac
    20461 acaccagagc agttattgat gaatcctaaa aacgactacg ttcggcattt ctttgatgaa
    20521 ccgaaacaga cgaaagagtg gcgagtagaa gatttagtcg tcaatggata tttcttaaat
    20581 gaaataccag aaaatgctcg tcaacaagtt tgctttgata cgcctatgaa agaagtatat
    20641 tcgcttcttt cggtgtatcc aagcattgtg atagtagaaa agcaaagaag tattgggtcg
    20701 ctgacaagta aagaaatctt tgctttttta agtcgagagg aggaaggaaa tgaaaacata
    20761 tgatgcaatc atcatcggtt caggtgtgag cggcttaagt gctgcttatg gattgaaaga
    20821 agcaggtaaa acagtactag tggtcgaaga agatctatgg ggcgggactt gtcctaaccg
    20881 tggatgtgat cctaaaaaag tcttgttaag tgcagtagag gcacgtaatc gggtaaaaca
    20941 attgagtgga aaaggtttta acgagatccc aactgccaac tgggaagaac ttcaaaaatt
    21001 caaacgaaca tttacggatc cagtcccaga aagccgaaaa aaacaattag cagaagctga
    21061 aatcgatcat ctttcaggaa ccgctcgttt tttggatgat tcatctattg aagtcaacga
    21121 agaagtcttc catgcggatt acttagtttt ggcaaccggg caaagaccta cgatcttacc
    21181 agtggaggga aaggaatact tgaaaactag tgcagacttt ttatcattgc ctgtactgcc
    21241 taaagaaatc atttttatcg gtggtggtta tattgctttt gagctagcta cgattgccaa
    21301 tgctgcaggg agcaaagtaa ccattgtcca tcataatcaa cggccattaa aagaatttga
    21361 ggcgtctttg gtagaggaag ccgtccatca aatggaagca tctggcattc agtttgcttt
    21421 tggtgttgaa acccaaaaga tcatttcaga aggtactcgc tatcgtttag tcggaaaaga
    21481 gacggaatta gtagcagata tgattttttg tgcgactggg agacagccga atacagaatc
    21541 tttagcactt gagcaagcga atatcgtctt tgataaacac ggaattgcag tcaatgatta
    21601 tctgcaaacg agcaatccaa aaatttttgc gtgtggagat attgtttcaa ggaaaacccc
    21661 aaaattgaca ccagtcgcca cttttgaagg aaattatgta gctaagcgga taacggatgc
    21721 aacaagcgaa cctatcaaat atccgattat acctacgatc gtctacgcca gtcctaaact
    21781 tgctgaagta ggagttacaa aaagtcacgc ctcttcgtca gatcaagtgg tagagatgga
    21841 tcttaccagt tggttcacct atcatcgtgt caatgaacca gttgctaagg ctgaattgac
    21901 ctttgaccag caaaattatt tgattggtgc tgcagtgatt agcgagcaag cagacgaatt
    21961 gatcgatgat ttgacactcg tcatcaatca aaaattgact aaaaaagagt tggatagcta
    22021 tatcatgggg tatccgacat tggcaagtga tctctcctat ttattgaaat aatcagcatg
    22081 ataactaaag cgcttgttgc tttttccttc ttgtgctaca ctttaaaaaa tgaatacctg
    22141 tttctgggga tgtcgtagac gacatgagag taagttgtga acttagaccc attgaacctg
    22201 tcagttaata ctggtgaagg gagaaacata gcagacgctt gaagcgggtt actatgtcgt
    22261 gcccatttca agcgtttttt gttattcata ttagaagaaa ggaggtaaca aaatgaagaa
    22321 aaatctttat ccagcagtca gtatggcatt cattttaatt atttggcaga ttgttgtcat
    22381 agtttggaaa atacctgcct ttattttacc cggacctgct gctgtatttt ctgcattagc
    22441 ggcagatgca caagtattac tttcccattc tgtcacgaca ttaaatgaag cagtgcttgg
    22501 tttggtaata gctagcgttc tttcttttat tactgccttg gcaatggatt attggaagtt
    22561 tttagaaatg tctttttatc cgttactagt gatttcacaa atgttgccaa tcatggtgtt
    22621 agggccatta cttaccctat ggtttggttt cggtatgctt ccaaaagtga tccttgttgt
    22681 cttgataagc tattttccga tcgtagtttc tttttcggat acattgagga aagtatcaaa
    22741 agagcaaatc atctttttga aaacgatggg ggcagataca gggaagattt atcgaatata
    22801 taaaatacca gcgggtttat ccggcttctt ttccggttta aaagtggctg ctacttattg
    22861 tgtcagcgga gcagtcgttg gagaatggct aagcgctcaa gcaggcttag ggtattacat
    22921 gatacgcgta aaaaacagct accagatcga taaagttttt gctgcgatca tttgtgtcat
    22981 tctattgagt ttattgctga atggcgcttg ttcattattg aaaaaagggt attatcgtat
    23041 gctttatatt ttttaagaga aggggatcaa atgaaaaaat tatggctttt attaccgcta
    23101 ctgttgcttt tatccgcttg tggcactgca aaagaaacaa gtagcaaaca agaaataaag
    23161 gatttgaaaa aagtgacact tgttttggat tatgtaccga atactaatca tactggcatc
    23221 tacctagcaa aagaaaaagg ctattataaa gaggctggtt taaatgtcca aatcatcgaa
    23281 ccaggagata attcgacaag tattggtcta gtaggtgcgg acaaagcaca atttggtgta
    23341 agttatcaag aagatgtcac ttatgctcac gcagatggac agaatatacc agtcaaagca
    23401 attgctacag tgatcaaaca taatacttct ggattcgcca ccctatcaga cagtaacatc
    23461 cattcaccaa aagattttga aggaaaaaca tatgcaggtt ggcaaagtcc aagtgaagaa
    23521 gctgtcttaa aagctgtgat ggaaaaagac ggcggggact tttcaaaact gacaatggta
    23581 ggaagcaatg gagaagggcc agaaagctta ggaaaatcct cagatatcca atggtacttt
    23641 gaaggttggg atatgatcaa agcaaaagaa gcgggtattg aactaaacta tatcccattg
    23701 aaagaattag atgaacggtt agattactat actccggtaa ttattacgaa tgatcaactg
    23761 atcaaaagtg atccagaatt ggtacagtct tttatggatg ccacgaaaaa aggctatcag
    23821 gaagctatta aggatccaaa tgacagtgct aaactgttgc aaaaatatgc aaaagaaaat
    23881 gatcggacgt ttttagaaga atcacaagca ttcttgtcaa aaaattatac ggatgatcct
    23941 gagaattggg gattgatgga agaaaaagtt tggcgcaatt atacagcttt tatgcaggaa
    24001 aacggattga tcaagcaaga tgtaccttcg caagaactat tcactaatca gtttataaaa
    24061 taggagtgat agatatgtca atccaaatca gccacttgaa tgtagtcatt gaaaacctga
    24121 aaatattaga agacatccat ttcactatcc ctaaagatac ctttacatcg attgtcgcgc
    24181 caagcggagc cggtaagtca acattgctga aaactttaac aggagtccag cctatgactt
    24241 ctggaacgat caaagtagac gatcaaaaag taactggtct ccatacagca tttagttata
    24301 tgccgcaaga agatatgtta cttccttggc tgagcgtcta tcaaaacgtt acgttatatc
    24361 aaaaaatcaa tcatctaaca atcaatgaag aacaagtaag ggattatctg gatatctttg
    24421 ggttaaacgg ctatgaacat tttttgccgg aacaattatc tggcgggatg aagcagcgaa
    24481 cggccttgtt acgaacaatc atgaatcctt cttcttactt gcttcttgat gaaccatttg
    24541 gagcgttaga tgctatgacc agagggcaga tgcaagactg gatgttgaag ctgcctaaaa
    24601 aagcaaagcg gactacttta cttgtgacgc atgatatcga agaagcaatt tatttatcag
    24661 acaggattct tgtgctttcc gcccgtccgg cacatgtgat tgctgagatt caagtgcctg
    24721 aaaaacgacg gtcacgtgaa tggctactgc agcaatcaga gttgaagcaa acgatttatc
    24781 agttattggc aggtgaatta gatgttaagt gatgctcatt gtcatttaga tgggagtcag
    24841 agtttagcac tccttcagca ggaacacacg attttgacga tcatcaattg tgattcgcca
    24901 gaagaatgga aggaaaacag acagcttgca gcaagtaaga ctcaagcctt aagttacggt
    24961 atccatcctt ggaaagcaga tagctatacg tttgaacaag ttgagccttt tttgaaaaaa
    25021 gcaaggatca tcggtgaaat agggttagat aatatttgga cgaatgtacc gatgactaca
    25081 caaaaaaaag tatttgagcg acagcttgct tttgcagcca taaatgagaa acctgttgta
    25141 ctgcacacaa aaggatgcga aaaagagatc ttaaattata tccaagctta ccctaatcac
    25201 tatttgatcc attggtattc ttctttggac tatcaacaag actatattga tttaggctgt
    25261 tatttcagca ttggtcttga tttgaaaaag aatccagcag tctggcaact agctaaagca
    25321 gtcccaatcg accacttact tattgaaacg gatggactac atgcagcaga gtgggcttta
    25381 ggggggattt tttcagaaaa agattatgtc tcactgcttg aagaacagtt aaagacaatc
    25441 gctgagatca aagagctatc agttgaagaa gttaaaaaaa atacttatca aaacttggaa
    25501 cgtttcatta gattaggtaa ataaaaaaga gatgtgacac aactagtgtc gcacctcttt
    25561 ttggctttct ttgtataaaa gtaaactgtt tgattaataa atgaatctta gtaccaaccg
    25621 tttgcttccc agaatgcttt cgccgcttcc caagaaccat aacgtgaagt aacatattgt
    25681 tctgctactc tttcttggtt tgcagcagag tagtcaccat ttaagtaaga agaatctaat
    25741 tggtaacgtc cgatgtaacg tccgttcgtt gctgtgtaag aaccgcttga ttctttttgt
    25801 gcgatccatt cttttgcaga gcttgtgctt gctggagtag cagcagtttc tgttacagca
    25861 ggagcaggtt gtgtttcagc aacaggcgct gcttgttttt ccgtttgaac cgtttcttgt
    25921 acaacaggtt gttcagcttg gactggtgct tcttgaacgg ctgcttgagg ttcagcagct
    25981 gcttgtgcag agccttctgt tgggattgtt aattgttgtc ctgagta
//
LOCUS       DARPZF010000036        25936 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.037, whole genome shotgun sequence.
ACCESSION   DARPZF010000036 DARPZF010000000
VERSION     DARPZF010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25936
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.037"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(1236..1901)
                     /locus_tag="SLE65_001854"
     CDS             complement(1236..1901)
                     /locus_tag="SLE65_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8449148.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2081..4063
                     /locus_tag="SLE65_001855"
     CDS             2081..4063
                     /locus_tag="SLE65_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEI8449149.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4067..4705
                     /locus_tag="SLE65_001856"
     CDS             4067..4705
                     /locus_tag="SLE65_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8449150.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            4733..5161
                     /locus_tag="SLE65_001857"
     CDS             4733..5161
                     /locus_tag="SLE65_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449151.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     EKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            5618..6529
                     /locus_tag="SLE65_001858"
     CDS             5618..6529
                     /locus_tag="SLE65_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HEI8449152.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            6746..7183
                     /locus_tag="SLE65_001859"
     CDS             6746..7183
                     /locus_tag="SLE65_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449153.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            7278..8162
                     /locus_tag="SLE65_001860"
     CDS             7278..8162
                     /locus_tag="SLE65_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEI8449154.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            8386..11553
                     /locus_tag="SLE65_001861"
     CDS             8386..11553
                     /locus_tag="SLE65_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449155.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            11573..12118
                     /locus_tag="SLE65_001862"
     CDS             11573..12118
                     /locus_tag="SLE65_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HEI8449156.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            12146..12601
                     /locus_tag="SLE65_001863"
     CDS             12146..12601
                     /locus_tag="SLE65_001863"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HEI8449157.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            12598..13356
                     /locus_tag="SLE65_001864"
     CDS             12598..13356
                     /locus_tag="SLE65_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HEI8449158.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(13442..14182)
                     /locus_tag="SLE65_001865"
     CDS             complement(13442..14182)
                     /locus_tag="SLE65_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8449159.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            14243..15496
                     /locus_tag="SLE65_001866"
     CDS             14243..15496
                     /locus_tag="SLE65_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEI8449160.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            15818..16045
                     /locus_tag="SLE65_001867"
     CDS             15818..16045
                     /locus_tag="SLE65_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEI8449161.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            16168..16494
                     /locus_tag="SLE65_001868"
     CDS             16168..16494
                     /locus_tag="SLE65_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HEI8449162.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            16562..17275
                     /locus_tag="SLE65_001869"
     CDS             16562..17275
                     /locus_tag="SLE65_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HEI8449163.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            17585..18436
                     /locus_tag="SLE65_001870"
     CDS             17585..18436
                     /locus_tag="SLE65_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEI8449164.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            18557..20422
                     /locus_tag="SLE65_001871"
     CDS             18557..20422
                     /locus_tag="SLE65_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEI8449165.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            20470..21879
                     /locus_tag="SLE65_001872"
     CDS             20470..21879
                     /locus_tag="SLE65_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEI8449166.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            21987..22688
                     /locus_tag="SLE65_001873"
     CDS             21987..22688
                     /locus_tag="SLE65_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8449167.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            22847..23326
                     /locus_tag="SLE65_001874"
                     /pseudo
     CDS             22847..23326
                     /locus_tag="SLE65_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            24174..24749
                     /locus_tag="SLE65_001875"
     CDS             24174..24749
                     /locus_tag="SLE65_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HEI8449168.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            24749..25189
                     /locus_tag="SLE65_001876"
     CDS             24749..25189
                     /locus_tag="SLE65_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HEI8449169.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            25205..25906
                     /locus_tag="SLE65_001877"
     CDS             25205..25906
                     /locus_tag="SLE65_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEI8449170.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         8758 a         4214 c         5352 g         7612 t
ORIGIN      
        1 ctacctgtat tagtcctctt ttttgaccag attttgacca gtctatttta cattctaata
       61 tattcatatg agctaatttt atgattaaat ggtaagtgtt tccttgtttg ttttagttta
      121 aactagtgtg taatttaaaa atctatatgg aagggtctgt ggggtaatac ttaaataaag
      181 gctaggaacc tgataacatc aaggttccta gcctttttat aataaaatga agcgaaaata
      241 atttctttta aagagccgag attatcagct atataagagt gaatttgatg caaaaaacag
      301 agccgaaaca gtcttggtgt tcgtagctct gcttatatgt ttcgaattta agacaaagag
      361 ttggcaaaag atgttgataa ggaagataag ataactgtgt tatataaact aggtaactaa
      421 ctgtaacaag ctaattttaa gagattctta ttagaagacg tttaggaata taactaagaa
      481 aatgattata caggtaattg tcatttcaat aatgttttct aattttcgcg tctttgtttt
      541 aagaaaaagg ccagaatcag ttggaaaaaa gttcgtacga tagtgaagag gggcaaaatt
      601 tcctactaat attcccacta acaagagata aaacggccag gttggtgtga ttcctctata
      661 aaaaaatgcc catgctaccg aaatcccata gattaacaac tgaacaattt ttacaatgaa
      721 aaaattgttc tgccattact caaagtctct tcctccttgt atcgtttatt tgtttcattt
      781 tatcattatg ataggcgctt gaacaatcca ttttgtattt tattgagtac tcttggataa
      841 actaccagcg attatcatat ttatttatgt tactgtaagc catcatataa aagtaaatga
      901 gcagatcata gaaatataaa aaagaactaa aattgatcta aattatgtgc agcttgacta
      961 cgtaccaatc tatattactt actagattgg tcgttaatct attcggatcg aatgagcaaa
     1021 atatttttgt gaatgtccat ccttgattat gattccaaaa agaatcattg ggaggctgtg
     1081 gcgtaaatat tatactataa gccagaaata cctatcattc tgaacttttt tatttaggaa
     1141 ctttcatctc aaggcttttt caattaattt gtacccctgt tttttggata agatcatgtg
     1201 cattgatttt ttctatctct acgttcatct cctacttaat gcctatctgg ctcctgaggg
     1261 cttcttttta aggcgtcgtc atagtcttgg ctgaggattt cttggtaatc tgagggaatg
     1321 gcttcccaag tgagcaggcg aacattcatg acgtgttttc ctttgtgttt gattacagca
     1381 tggtttttct ctttttctac ctctccagcg tgaaaagaca gccatgtacc atggccaaag
     1441 atatcattac atacccaacg ttcgatggaa ttgtccacgt atcctacagg gagtgtggta
     1501 tagccgattt gtggtttcaa aaaaggattg aatcgatcga tcgtttcatt tttgtattga
     1561 taattgataa gaaaaagata gaccaaacaa aagacgagca gaaagaaaga tagtgtcttt
     1621 ttgagtgaga agggttgttt tgatgaataa gatttcttgt taacaagagg ttcatctggc
     1681 aatgttggtt ctattgattc ggtagctgat tcaatagaag gaaaatcaat cggcagacct
     1741 aaagtatgat gtaaaagtga cagcatttca aggtctggca ttgtacgaga attttcccaa
     1801 ctagaaatcg ttttatcgga aacaccaatt ttttcgccta attctttttg cgtaagctta
     1861 caatttctgc ggtaagttcg tattttttct ccggtgttca tcttcttctc ctttcgattc
     1921 tacagtatat agatttattc tacatgacct atacacttga tagatacgtt tttttgatga
     1981 aaaacggtat gattttatca aagaatcatt taagtaaggg agagtggtga taatcaaaaa
     2041 aaagttcaca gttttactca caatcatagt gaccggtatc atgagtggtt ttgccttggt
     2101 tagtataaat aaacaggtac tctatcggac aaatgaattt ttccatcaaa cagatactta
     2161 tactccgatt cgattgccac aacattttat tgggcaagaa gaatatgagc agctaatcat
     2221 ggtatttgaa aatgtctcat cagaaactga gctttcttat atgaaaaaaa cagtaaatga
     2281 atccaatgaa gtagatacat cttggaactt caagatacag ccaaagcttg aaatgacatt
     2341 gtattatcaa ggggatgtca aatcttctca cgagaaggta ccctattcta atacctcctt
     2401 tcgcgtaacg tccattgaag aatcgatcaa aataaaagat tttgaaggtg aatttttctt
     2461 gatgacgaga gaaaaagaag cctatgaacg gttcatttca ctattcactg atcgattcaa
     2521 tcaagcattt cacactgatt atgccactaa tatttttgaa gactttgaaa atagctattc
     2581 gtattcggtt atttcaaata cagacgtata taattatcga gtgtatttaa ctattggatt
     2641 gattctttta ttccttttgt tatcatcctt tttcttattg atgaataaag aaatcagttt
     2701 attgttgaat aatgactttt cattacatca agtattgtgg tgtttattgg ggaaaaagaa
     2761 aatcattatt acattcataa ttgcaggaat cattggtggt tttattttta tgtattataa
     2821 ggagcaattt ctttatttgt tccagatgta cgttttcttg ttcagcggaa tatatggtat
     2881 ctctttgatt tctcttttat tagttgaaaa aatcgcttcg ttaagagaag cgttcaacta
     2941 tatccaatac attcttttta catttggatt gttgttttct cttcttttga ccgttgccaa
     3001 tgtcgaatta gcaactatcg ttttttcttc ttcacagtta gctgtttccc atgaaccacc
     3061 aaaagaaatc gctggtgagg actatcatgt attttatcca gtaaccatcg ggaaaaacca
     3121 cgtggatttt atttattcca atcgttttgc atcagcagca gatcaggaat tatatgaaac
     3181 tttgaataaa aacggaagta tattagtcaa tgtatcagat tacttgaatg aagaaaatga
     3241 acagtttggc agagggataa aaataaatct gaattatctt aagaaatttc ctttgattga
     3301 tgtctctgga aggttgatcc aaataaccga aaaagaaacg caccctgtta tattgatccc
     3361 tgaacgatat agacatacag atttaaaaaa tgacctggcg caaataacag aatattatca
     3421 agaaatcagt gaaaaagaac cgaaatttct atttataaaa aacaatcaac ccatttatac
     3481 atttattcct tctatcccct ggatcgaaca ttatccggtt gttgaaatac tgacattgaa
     3541 aaacagtatg tatttggaaa gaaatattct cagcggagaa atctatccac cgttaaagat
     3601 caagataggc tctttgtcga aagaaaggtt atttgagctg attgaagaaa gtcagttacg
     3661 tgataacttg cagttatcat ttccgtatac tcagactgaa gagatagctg tcaaagtgtt
     3721 aagcagatca tttcattact tgatacagat atttttactc actttctttt ctttcttctt
     3781 gttgagctat gtcatgttat gcatatattt tgtctacaat tgtcggaaaa tcgctatctt
     3841 tcgttcaagt ggttattcgc tctttgaaac gtataaagat ttcttcatga tgaacctcat
     3901 caaatgggga acgacaagtg taatcttcct ttttcttata gaaagagagc ctaaatatct
     3961 ttttaatatt tttttcttta gcttcattga ttttattctt tcagttgttt ttattttgtc
     4021 tacagaaaag aaaagtcagt tattgctgat gaatggaggt taacaattgg agccgttgat
     4081 agtgataaaa ggtgcgaaaa aaatcattcg aaacaaaacg attcttcatt tggatcgttt
     4141 cactgcggat gctggggatc ttgtgactgt tgttggagaa agtggagcag gtaaaagtac
     4201 gttattgaat atattaggat tgaatgatca gttcagttca ggacaattct atttgttcga
     4261 tcaagagacg aaacaattaa ctgggagaga gaagcgcttg ataaaaagaa ataccatatc
     4321 ttttcttttt caagattttg ggttgattga atatgaaaca atcgatttta atttagatat
     4381 tggattgaag ttttcgaatt taaatgtttc agataagcga acagcaaagt atgaggcatt
     4441 gaaaaaagta aatataaaca agaagctaag tacgcctatc tacacattat ctggtggtga
     4501 gaagcaaaga atcgcctgtg cgagagtctt attgaagaat agcaaaatca ttttagccga
     4561 tgaaccgact gggtcattgg ataaaagaaa taaggataaa gtagttgaaa tcttatcgca
     4621 acaagcttcc caaggtacgt tagttatcgt agtcacgcat gatccatatc tgaccaaaat
     4681 aggaaacaag aagatcatgc tttaaaaatc aaaaaggaaa ggatgtcgtt ttatgaaaaa
     4741 agcagttatt atttgtgcac tagggatagg ttttgttgga ggaaacgcta tgtcatctga
     4801 agtggaagca aattcagttc acggtgaaat ctattacaaa tctttaaagc caggagagat
     4861 tcattttgat gctaaaggta atattattaa gtcaaattta ccagtagacc gggaaatttc
     4921 tagaacagca attaatcata gctctggaag atgggtttat tatagtgata caacttgtac
     4981 gagaaaaaca ggtcattcta accactatag tcgtgtctat aatcgtcacg gtgcaaaaga
     5041 gaaagttgga aactctattc gatcagcaaa tgcaacaaaa ggagtatggg cctatgcaag
     5101 tgcgacagga aatagaactg acacattctc atgttggtac aatccaaccg gttggtatta
     5161 agtatccaaa agtttatata aaatagaaaa aacatataat gaaacagcgt taaaagttat
     5221 ttttggtagt tttaatatat tcatttttag ttgtataaaa atatatcata ataaaaacaa
     5281 caaaaaaatg tctggaaaat cgaacataaa agtgtctgat ttgaatatcc cagcagcgga
     5341 agaagaaaaa caaaatcgat aacatttgtt ctaagaatta gttacgttaa atacggaacg
     5401 caagatagac ttgaaaaacg gtaacaaaag aagtagtata ttaaggtgtg atgtgctact
     5461 tgacatttat tctgctgagc gaactttctg gattgtgtag ccttatatct attcaggacg
     5521 tatcgagcag attagtaaag gtgttcttga tgattttcat cttgaacacc tttgttttta
     5581 gcaattcgca aaaaacgaaa agtaggagaa ttgataaatg aaaaaaagat ttttagcact
     5641 tgccatcgta ctaggcactg gcttattgtc aggctgtacg aatgccggtg aaaaaacagc
     5701 cgttagttat aaaggcggta caatcagcga acaagaagta atggatagct tgaaaaaaat
     5761 gcaaggagca gattccgctg tgcaacagtt gatcgtttat caagtatttg aagataaata
     5821 tggagatgac gtatcaacca aagaaatcga ttctcaatat gatcaaacaa agaaacaatt
     5881 gggtgattca tttgattcac aattgaaatc tgcaggttac acagaacaaa cattcaaaga
     5941 cagtatcaaa caaagtctag cctttcaaga aggtctaaag aaacatatca aattgaccga
     6001 tgaagattta aaaacggctt gggaatcttt ccatccagaa gtggaagctc aaattatcca
     6061 agtagcaagt gaagatgatg caaaagatgt gaagaaagct gctgataagg gagacgattt
     6121 ctctaaatta gccaaagaca agtcaactga tactacgaca aaagaagatg gcggaaaagt
     6181 gaaatttgat tccactacta caacggttcc ggcagaagtc aaagaagcag cctttaagtt
     6241 gaaagatggt caagtttctg atgtgatcac ttctaccaat gcttcaactt atactacgga
     6301 atattatgtg gttaaaatgg tgaaaaacca aaacaaaggc aacgacatgg ataaatacaa
     6361 aaaagaattg aaagaaattg caacagacac aaaattaagt gacagtacct tccagaataa
     6421 agtaattggc gaagtattga aagacgctaa tgtaaaaatc aaagacaaag actttgaaaa
     6481 tgttttgagt acattcactt cagattctag tacagcaagt agtaaataag cggtataaat
     6541 aaaaaatatg aactatttaa atcaataaaa ctgttcatct aaatcttttt attagaacta
     6601 aatcaacagt agtttaatta ctacttgatt tagttctttt tattttaaaa atttttttta
     6661 cttagaatcc agcgacccta gatatttttc tgtataatct taaataaaga aaacaatatc
     6721 aaaaaatgca cgtagaagta gataaatgga gtggttttgc aaatttcttt tatttctaga
     6781 agttattcac gtatacggat ttgtttttct cacaaataaa aaggcaggaa gtacaatgga
     6841 tcatttgtat ataaaatata ttcatcaatt ttccgttttg gtgttaggca cactaattat
     6901 agcggggatt gtcgcattta ttattcaagg ccgtgacata ttaacagtac atcaagagtt
     6961 tttcagttat gcatttggta ttcctctgat cgctataagg tctgataaca aaaagtggaa
     7021 gaaacgctat tacattctct tgctattttt gtgtttttat ctgccaccta agatttttac
     7081 tttattaggt atacaatgcc tatcattttc ttttatttcc tatatcattg ttttaatttt
     7141 cctcagtttc atagtatgga tgttttatct tgtcaaaaaa taaatgaatg tttcatgaac
     7201 agtacttcat cacagcctaa tttttttctt tatgctatcg ttatattaaa gaaatcaatc
     7261 agaagggaaa gaaagtgatg aaaaaagttt tattagtggt aaaccccagt tcaggcggtg
     7321 aacaagcaaa ggaatttgag caattagcga tagcaaaatt ggaatcggtg tttgatgaag
     7381 tggtcgtctt gcatacaaaa aaagcagggg atgcaaaaaa ctttactcgc gaagcggcta
     7441 cggaagggta tcatagtgtg tttgtcatgg gcggagatgg aacagtcaac gaaggaatca
     7501 gtggaatcgc tgaacaagaa catcggccaa atttcggatt tttcccattg ggtacggtga
     7561 atgacttggc tcgagcatta gggataccgc tagaacctga ggaagcgatc aatcattttt
     7621 cgattgaatc agtcaagcca ttggatattg gaaaaataaa tgacgactat tttatgaatg
     7681 tcgtcgcaat tggctctatc cctgaatcaa tcaatgatgt agatgcggag aagaagacga
     7741 aatttggaaa actagcttat ttcatgtcag gaatcaaaca gttagcttcc acacaatcct
     7801 actcgtttca cgtagaagtt gatggaaaga aggaagaaat tgagagcagt accttgctga
     7861 taggactaac taactcagtc ggcggttttg aaacattact tccaaatgca aaagtggatg
     7921 atggtaagct ccatttggtt tatttaaaag attcttcttt gatcgatacg cttaaaacat
     7981 tgccagacct attaaaagga gtagatgaat ctacgaaaaa tctagcctac cttacttgtg
     8041 agcaattagt tgtgtcatta gctgatgagg aagaattgac gacgaatgtt gatggagatg
     8101 aaggggataa attacctgtg acaatcaaag tattgccctc acatttacag gtttattgtt
     8161 aaaatggagg ttgtgaccga ggagttggcg ggagaacacc gcttgttcgg gataagggac
     8221 tgtgacaaga cttttgtcac agcctttttt ttgtacaaaa aagaaattta cacctaatag
     8281 aaaaattttt ccataaaaat acatatttta aatatgaaag tacaattgga aatagattaa
     8341 aacgataaaa taaaattgtc aaaacgtcag agaggatggt ggagaatgaa tcaatgtgta
     8401 aaaaagctga ttgcgtcgat tttgtttgtc ttccctctct tgatggtgac atccgttttt
     8461 gccgatgtag agaaaacaaa cgaatcaacg caatcagaga atcaaagttt tgacaagact
     8521 actttttcag aagaatcgat tacttctgaa actacagaat ctcaaagtga ggcttctact
     8581 aataaaaggc aagaagaaaa taagacaagt gagacctcag aagtagctga acaaacgtct
     8641 gatagcagtg aagcggcact ggcaagagct gtttcagcgg atgggtacag cgaagctgcc
     8701 acaacagaag aactggcgca gcttctcgca gacgaatcag taactaagat ccgactgatt
     8761 cagcctttga ctttagacag ggaattagag atcaaacgag atatcgttat tgattttggt
     8821 ggattcgctc acaatttcgg cacacaccat atttatatca atgagatacc tcagtcgatc
     8881 gagttccaga attttaaagg aacagctgca catccaggtg gattgacacc aaatatcgat
     8941 ggaaatgcca ttatcattgc ttatatgacc gatttttggg gaagcagata tcattttacg
     9001 ggagaaataa aatttaccgg gacacttgat ttgtatgatg ggtccaaatt aggactgatt
     9061 tacgctcctc gtgcaactgt cacattagat ggtgtttccg gtgtgttgga tgtccaacca
     9121 gtgaaggaag gactgaatgc cgctccgggt aaagcctatt tttgtagaag ctatcaattg
     9181 aatgtgatca atggtagtca actttatgga ccgtatctag ggaaattcta cggttttcta
     9241 gattcaggag atgagactgg tagtggaaaa acagcgccag gaatccatat cttaagcggt
     9301 tcaaaggtct ctcttgatta tgatcgggca gatggcgtta gcgatgaagg agaggcagtc
     9361 gatacgctac ctggtaatgt catgtttgaa gtcagtggtt cgggaagcga attttcggta
     9421 aatacaaaga tcaatattac caatgacaac aatcgcggaa tcatccaaat gagaggttca
     9481 ggatcgaaag tcactgtatc gaatggtggg aaaatcacca tcaatacagc aactacgggc
     9541 ggatttcgct tgcaaggaga ttctagtcaa atccatgtat caagtggtgg acaaatctcg
     9601 gtcaaaatgg ctggagatga cgatcaaccc gggaacaatg ggatgcgttt tgtaggaaaa
     9661 ggcctttctt tgatcgtaga aggagccgga tcagttatcg acatcgataa gcagagtggg
     9721 cgttccagcg cagttcgttt tgagaatggt acgcaaaagc tgacagtaac caatggaggc
     9781 tcattgaggg taagaaatac aggtgatggc aaatcttacg tgaacagact caatcaagga
     9841 aatcaagcga tccaatttta tgacgcttct ggttttctag aaagtccagg ttcagctgat
     9901 tttacagtca ctggagaaaa atcaaatatc gatatacgcg cagattccgg agcaactgta
     9961 gatacaactg gagatattga tttaaatttt acggcaggtg aaaaaactta tttagtcatg
    10021 gtcgggaaaa caggggaaga taagaccggc atcatcagtg gggatgtgtt gaatgtggac
    10081 ttagaatctc ctacctattt tgatttccaa aacaaacgga ttggaagcga gaccaatggc
    10141 ataggcggct gggtattcca aggaaatgga gattcttctt taaagatcgc ccattcagaa
    10201 atcgctttat ggcgaaaaac aggcgcaaca ttcgataact ttgaaaaaga cccggattat
    10261 ttttctgata tgacagactt atcgatcaat gggaccgact taggcaattt cgtatcaagc
    10321 cctagtgcag gtttaacaaa tgaatttgct cagacaggtg ccggaatgaa aaattataat
    10381 cgaatcagtg ccaataatca gctcccgatg attgaatcct taagagtgcc aacgaatgca
    10441 gataaaaaaa tctatgggca tgtcgttgtt cccgaaggtg tcgaggcaaa gccaagagat
    10501 gcttggacag gcgaagtaga agtgacttta cgtattactt acgcagatac gacgaaatca
    10561 tctgtagaaa ttactgctct cacgcaagga caaacagatg aaaatgaagg ggcaggatat
    10621 aacccatggg gagaaggcga acaaggcggc ttgttcgaag ttcaagtacc caatgatgag
    10681 agattaaaaa cggaggatca agtgcaagtt gttgctgcta aaaaagtaag aggtggccaa
    10741 gaagtgacag aactggactc tgccaaaacg acagtcgatg tgattcctcc tgaacctgct
    10801 aatttaagta ccacattgat caatgcagct tctcgcacga tcacaggtac aggtgaagca
    10861 ggagccttgg tttcattgaa aaaaaatcaa gctgttttgt cagaaacaac tattgatgat
    10921 acaggggaat ttgttctttc tatcccagaa aatcaacttt ttgcaggaga tgtattagaa
    10981 attgtattaa acgaccaagc aggagaagct actgctaagg gtgtgcagaa caagccaagt
    11041 accaacgatg aaattgggaa tcacaatcca agtgatacgc cagttgttta tcatgatgcc
    11101 ccgccttttg cacctgctac gaagatcgta gtagaaggtg gtctctcatt tcttgcccct
    11161 tccaaactcg attttggtca gatcaaagca actggtttga cacaagaagc atttggccaa
    11221 atggatatac aggaaaaatt atggatttat gatcagcgag aaacgaaaaa tccgtggatc
    11281 ttaacgataa aattatctca gcctttcaca aatgatgcag gattttctat gcaggatgtc
    11341 ctatatttca agaaaggaga ggagtatcaa ttagtgaatg aagaagaact ggaaattgtc
    11401 agaggacaaa attcaacgaa tgtgcaagca gattattcag aatatttaaa taacggtcgg
    11461 gcgtttaaac ttgtcttaac caaagaaaat cagatagctg gtaattactc agcagagata
    11521 acatggacat tagcagatgc gccgacagaa taaagatcaa ggaggatgat tgatgaatcg
    11581 aatatggaat aaaagtcatc gaaacaactg ctctttactt atgatccttc tccttggatt
    11641 catcctttgg cagacacctg tccatgcctc cgaattcaat tttgcggtag attttgaatt
    11701 accggctaat cagattgata agaacaaaac atatataaat gtaaggatgg agcctgggaa
    11761 aacacaggaa atcccctaca cggtctttaa ccgaacagat aaatcagtaa cagttgagac
    11821 attgatccac tccgctacga cgaattcaaa cggtgtgatc gaatatggag aatcaaaaag
    11881 taaatttgat gaaacattaa gttatgatat gaaaaactta gcaaaaacag tgggagaaat
    11941 aactgttcct cctcaaagtg cggtcactga gacactttca ctgaaagcgc cagaaaaaga
    12001 gctggctggt gtggtcgcag gagggatcac gtttcaagaa aaaaaagaga acgtttctaa
    12061 caaaagtaca gttggtgtcg tcaatcagtt ttctcaagtg aaagcaatct tgatttgaaa
    12121 tagcgaaaaa gagtcttccc cagatttgaa attaaaaaaa gcttatgcgg atcaaagcga
    12181 tggaagaaat gtgattaagg cgaatcttca aaatccaaat gcttcttata tgttcggctt
    12241 gactacatcg gttgaaatct acaaaaaaga aacaaaagag ccttaccttt caataaaaaa
    12301 agaaaaaata gatgtagcac ccaatacaaa ttttgattta cttgtcccat tagaaggaaa
    12361 aaaattagct ccgggacatt atcaagcggt tgtgaagggt gcttggaaag aaaaacgctg
    12421 gaatctccat accgattttg aaataactga tgatgcagcg gaccaattga atgaaaagga
    12481 tattgattta aaaaatcagc cagaaacatt tgactggcga tggctgatac ttgttggagt
    12541 cattcttatt ggcttatttg ctggattatt tattttaaaa gaaagaagga aaaagaaatg
    12601 aaaaaaacaa ttgcattaag taccgttcta gctggaagtc tattattatg tacacaaagt
    12661 gtttttgctg agaataagag ctcagccact acagaaggaa cgatttctgt gaccaaacca
    12721 gatgctgcaa atcctgaaga cgttgttcca gttcctcctg ttgatccaaa tgatcctgat
    12781 actcctttta cacctgacga accaaatcag ggaacatccg gattactgac gattgaccaa
    12841 gctccagatc ttgattttgg aacaatcaag ttaggtacag caaaaacagt atatgctgca
    12901 ttacaaagcg gaacggacag tactggagca caaacacaag tacagaattt cgtacaagta
    12961 acggataaaa gcggaaatta tgccggttgg aaattatcag tcaaacgaac agaatttatt
    13021 ggtacaacat ctgatacgaa taaactaact ggttcaaagg tgaaattcaa aaacgccgtg
    13081 attcgaaata gcgcaactaa tagcagtgga atgccatcta ccgtttctgg aactggcgct
    13141 gaaggaatcg aaatcccagc agatcaggca gtagatctag taactgcagg agcaaatgaa
    13201 gggattggca catggattta ttcattagga gagaatgtgg aacaagggag acaatcagtg
    13261 gaattatttg ttcctgtatc caattatgct gtagacaact acgtttcaac attcacatgg
    13321 tcgttaacag atgctcctac agaagaggaa gcgtaaaatc atatcaacga tttcagggag
    13381 tggagccgat tcaaggccca ctccctgaaa tctgctatgc ttacgtctca gctcttattc
    13441 atcaactcga agcagttttt tggaagtcat ggaaacgttc ctttgtcttt tcaaagatct
    13501 ttcgaccaac gagtaaggag tcaccgttga aaaattctaa cacataatga gcagaatcaa
    13561 ttttctgcaa ttgcgataag ttgatacagt aagattttaa aagtaaaaag taagcatact
    13621 tttctaactc tgtcttcaat tgttttaaag aagtattcac taatttatct tctgtagttg
    13681 ttttgaccat aacttggttt ttcaaacctt tgatactttc aatatataaa atttcccgag
    13741 gatacaggac gagacttcca cctttttgat caataaagat tttatcgaca tttacgatct
    13801 gctgttcttt ccaattgatc tgttctagca cttgacgaat ttgttcagat aaattcctgt
    13861 cttttctgat atatccaatc ggaaggattt tccgattgat gatctctact gcaaaattcg
    13921 tataagcggt gaaaaaaaca atattactat gtgcattttt tttacgtatt tgttcggcga
    13981 catcaatacc tgtgagtgat tgcttcaagt cgatatcgat aaagaaaaca tcgtgattat
    14041 caatagtgcc caactggatc aactgattga tttgagagat agaagtgagc tgcacgatat
    14101 tctcgatatg atgattgacc aattctctga tgatccattc gctgtgaaac tggttatctt
    14161 ctatgataaa atactttttc atatgcaggc tcctattaaa aaaatatgtg tacattttga
    14221 aacaaaacaa tggaggaata agatggtcgc aacagtgaca ctttatttga cctttacttt
    14281 gattttagat ttaggtatct atttattctt ttcgaaacaa ctgctagtaa aaaacagctt
    14341 tggttgtata gctttgatgg tggtgacact tttacttcct atccctaaag tgagctttcc
    14401 ttacctagtt ggcttattat tgatgtttct tttttatttt actacgaaaa acctgtttat
    14461 cagctgtttg atcagtaatc ttttttttgc tatcactgga ctcagctttt ttctggtttt
    14521 tgatctgatg gattatttag gaaagagaca tcttggaaca gcaagttttt ttgcactact
    14581 tatcgcattt attttctatc tattagtaaa aagtatagac aaacagacga gatttctcaa
    14641 cttgcttttt acttatccaa ctgaacacta ttttggaggt atttgtattt tattaagctg
    14701 gggcgtgatt tacttggtat tgggaagtgt tcacttccgc tcatctaatt atctgcttct
    14761 atctcttttg tcgatagtca tcagtttttt ttctttgttt ttttccatta tgttgatcag
    14821 tttccaagta aaagaaagac aacatcagga atcgcttcaa ctgtatcaaa taaatgaaga
    14881 atattaccat catctagagg aattcaaaca tgattataaa agtctactgt tttcattaaa
    14941 aattactctt caggaaaata aaaaagaaac gttggaattt ttagaaatat tagaagatca
    15001 ttctgcagct atttttgaaa aaccgcaaat acaacagcta acaaatattg tatccccagc
    15061 tgtcaggggt gtctttttaa aatttctaga aaaagcagaa tcggagaaaa tcccgatcca
    15121 agtagttatt cctgtcgaag tgaaaacaat cccgattgat ctggttgttt ttattcgctg
    15181 tttatctatt tttatttcta acgcattcga tcatcgtgta gccgatcaga gtccgattac
    15241 gatcaatctg ctggaagaaa aagagggatc acgttttagt atagcgaaca aggcaaatcc
    15301 aacgaatttg acgctatcgg agatggtcaa aagaggaaaa acctctaaaa aaaatggcgg
    15361 gttaggtcta tacagtgcga aaaaaatgtt ggatgtttac gaaaatgcag aactaaaaat
    15421 cgaattttca aaacagaatc actatttttt tgtagaaatg tatctggcat ctagaaagag
    15481 caaatcagcc tactgactta ctgtcaaagg ataagtttga ggaaagtcta cacggagata
    15541 gagacaacaa cacagcatat tcaaaagaaa cagaagcgtg atgaccgttg tcacccttct
    15601 gtttcttttg ctatgtagtt aaacaaagta gttgacactt ccgctactta gtattagtac
    15661 gaaagtatac ttcatgatac taagtagata agaagtgaaa agcggaaccc acgatcgtca
    15721 aaatgctaac tgctttgctt acaccagata aagggaagag caatatcgct tattttaggc
    15781 gtggagaagc aagcaaatcc ctacgatcac aaaaaaaatg ctgacccagc agttaagaga
    15841 gttagaacaa gatgaaagta tccatcgaaa agcctataac caagtcccgc ctaaagtaga
    15901 gtactcgctc accgaagaag gaaaatcatt aagagagatt ctagtagcgt tgtctgtttg
    15961 ggaagaagaa cgtatcgaaa aacaaaaagc ctcaagggaa gaagacacgc tactgcatac
    16021 acatggtggc tacctaaatt attgattttc tatgacattt attttaaata aaagaaaaca
    16081 ggagtttttt taaaagcatc atctattttt tatgtaaaaa aatggtatga ttaatcaagt
    16141 aagaagtgat tggaagaagg caagcaaatg aatagtatgg aaaaagtcaa ccagtttaga
    16201 gatgaacgta attggcgaca atttcataac gaaaaagatt tggctatctc tatttctttg
    16261 gaagcatctg aattgttaga actttttcaa tggaaaacgc cggaagaagt aaaagaaaca
    16321 caattagaac gaatcaaaga agaactggca gatgtattga tctattcata catgatggca
    16381 gacaaccttc acctggatct agatgagatc attgaagaaa aattgatcaa aaataatttg
    16441 aaatatcctg tagaaaaaag cgcaggtgta cgaaaaaaat acacagagtt gtagaaatgt
    16501 gtcattcggc tgttggaaag agcaaaagaa aaacagtaaa atgagtctgg agggagagaa
    16561 aatgaaaaaa aaaggaaaag caaaaagatg gctagtcaat atcctcttgt tcctcttgtt
    16621 attagtagga ctagctttga ttttcaatga acagatcaag gattattttg tcagagagac
    16681 aggagataaa tatgctatag cgaatgtaac aaaagaagat ctgaaaaaga ataacgataa
    16741 agatgtcagt tttgactttg atgcggtaga accaatgacg acagaagggg tcatgaggtc
    16801 gcaaatgaga ggaacagatc taccagtgat tgctagtatc gcagtccctt cagtttcaat
    16861 caatttaccg gttttcaaag gcttggataa tacgtcacta ctttacggag caggaacatt
    16921 atctccagat caagaaatgg gaaaaggaaa ttatgcctta gcaagccatc gtgcaacgaa
    16981 ccctgaattg ctgtttacac cgctagaaaa tttagagatg ggtgccaaga tctatttgac
    17041 agatttagaa aatgtgtata catacaaaac attttttaaa gaaaaagttg ctcctacaga
    17101 tacccaatta ctgaatgaag tcgagggaaa agaaattgtc acactaatta cttgtggcga
    17161 catggacgcc gtcacgcgac tagttgtaca aggagaactg gaaagtgtta catcgataaa
    17221 agatgcgaca gatgatatga gatctgcttt caatctagag acaaaaacat tttaggatac
    17281 tgggacataa gtcgttacag attaaaaaca gccaaaggat atgaatcgat aaggaaaaac
    17341 caatttgctg aaaaaaagag aaacgcaaag aggtgcatct ctgatttggt tgttttctag
    17401 atagacttgt gttccagttt ttttattttt tatatgaaaa ggcttgcata aataaaaatt
    17461 cgatggtatg atgattttga ataagaaatg gattgttact gtacggcagg caaaaccaga
    17521 attcagctaa gaaacagtag gcgaattcta ggttttttta tttttcttga gagggcgaag
    17581 caaaatgaaa attgataaaa ttttgaataa caatgtcgtc atttcgaaaa atggattcgg
    17641 ggaagaagtc gtttgtatgg gaaaaggact agcttttcaa aaaaagattg gggacgagat
    17701 ttcgccagaa gcggtccaaa aagaatttgt tttaagagat tcttttgcta aaaaccaatt
    17761 ccagcagctg atggctgata ttccggcaga ggagatcgaa tgggtcaaac aagtagtcga
    17821 actggctgaa gataaactaa aagttgaatt ttcgcctaat atttatctga cattgaccga
    17881 tcatcttcat tatgcgatca cacgagcaaa agaaaatatc caactgccta atccattatt
    17941 atttgaaaca aaaaaatttt atccgaaaga atatcaagca gcgaaagagg ctcttttgtt
    18001 cgtgaaacaa aagacgggtg tggaactttc tgaggatgaa gccggtttta ttgcctttca
    18061 ttttgtgaat agccaacaag gaaacgaaga catgcaagtg acgatgaccg ctaccacaat
    18121 ggtaagagat atactgagta tcatcagtaa attcttcggc atcgtgttcg atgaagaatc
    18181 tttgaattat cagcgtatca ttactcatct gcagtttttt gcccagcgtt atctcaaagg
    18241 ggaaggatct gacgagcaag atgaatttct ctacgcatta gttcaaggaa agtatccaaa
    18301 agcgtttcat tgtgtcgaac ggatcaatga gtatcttcga caaacgcaaa aacaggaaat
    18361 ggggatcgca gagcagattt atttaacgat tcatattcaa agagtagtaa gtgagaaaaa
    18421 aagcatccaa tcataaggat tgttactgta tggcaggcaa aacctggatt gaaaaaatag
    18481 gttcacgaat gtttgtgact gtttttttca atctgggttt ttatttttta aataaaaaag
    18541 aaagaaggaa aaaacaatgg ataatcaagc agttggtcgt cgtgtatggg aagcggtagg
    18601 aggacaaaag aatgtcaaaa gtttagtaca ttgtgctacg cggttgcgat tcagattaaa
    18661 agatgaatct ttagcagata cgcaaaagtt aaaagaagac ccggacgtga tccaagtcgt
    18721 acaaagtggc ggtcagtatc aagtagtgat tggcagtaat gtagcagatg tttatcaatc
    18781 gatcgtggat gaggaaggtc ttgcagtttc ggaggatgga aaagaagagt ccaaaaatat
    18841 tttgaatcgt ctgatcgata ttatctctag tatatttaca ccttttctag gggcgatggc
    18901 agccgccggg gtattgaaag gattcttatc attggcaacg gtgatgggct ggctgacagc
    18961 tgatagcggt acttatcaaa tattgtttgc tgcagcagat ggtgtcttta ccttcttacc
    19021 tgtcatgctt gcttttacag cagctaaaaa gttcaaagcc aaccagtttt tagcagtagc
    19081 aattgctatg gcacttgtgt atccagctat cacagcagtt gctggtgcgg gagaagctat
    19141 cagtttcttt gggatcccag tgattctttc accatctggt tatacttctt ctgtcatacc
    19201 aatcattcta gccgtatggg ttcaaagtaa attagagcca ttcgtaaaaa aagtgattcc
    19261 gcaatttctg caaatgattt tagttccgct tgtcgtttta gtagtgatgg ttccattaac
    19321 atttcttgct ttaggaccaa tcgggacggt tgccggtaat gctttaggcg gtctcttcaa
    19381 ctcgatttat ggatttagtc caatcgtagc aggtctaatc atgggaagtt tatggcaagt
    19441 attcgtgatg ttcggcatgc attggggatt cgtaccgatc atgtttttga atatcgaaca
    19501 atatgggttt gatgtattga tgccaatgct tcttccagcc atcttggcac aaggtggggc
    19561 tgctttagct gtagcattgc gaacaaaaga tacgaaactt cgagcattag ggatttcttc
    19621 tacagtgact tcgttatttg gaatcactga accaactgtg tatggtgtga cattaccttt
    19681 gaagaaacca ttcattgccg cttgtatttc tggaggtatt ggtggagcta ttatcggatt
    19741 ttccggagta aaagctttct ccagcagttt ggtcagctta ttgacgattc cgactttcat
    19801 taatacggtg gatggtgtag agtcaaatgt gacagtagca gtaatagcta caggaattgc
    19861 ttttgttctt gcattcgtag gtacattgat tttaggattt gacgaacaaa cacaagacaa
    19921 tcaattagaa aacaaacatg cgaatgcagg agaaccgatt acttcagcac ggcatacctt
    19981 aaaaagtcct ttaacgggta aagtactgcc attgagtgaa gtaccagacc aagttttttc
    20041 ttctggcgtg atgggaaaag gtatcgctat tgatccagaa gtaggagaac tagttgcacc
    20101 tgcagacgga gagatcacga ctatttttcc aactggacat gctgtaggga tcacaacgac
    20161 tgacggagcg gagattttga ttcatatcgg gatggataca gtagaattaa atgggaatgg
    20221 ctttgagatc ttagtcaaac aaggggatct cgtcaaagca ggagatttat tgattcgttt
    20281 tgacatcgaa gcaattagag cagctggcta tagcgtaatc actccagttg tcattacgaa
    20341 tactgatgca tttgccgata tacttgaatt agaccaaaaa gagattattg caaacgaaga
    20401 tgttctggca attgtaaaat aaggaggaaa tcaggatgca atcacgtttt tcagaaaaat
    20461 ttttatgggg tggagcaact gctgccaaat caattagaag gggcttatga tcgagacgga
    20521 aaaggactat ccgttgcaga tgctatgcct ggaggtaagc agcgctttgc gattatcggc
    20581 agtgaagaat ttgactggac gattgatcaa gaaaaatata tttacccgaa tcatcgagga
    20641 atcgatcatt acgatcgttt caaagaagat cttgccttgt ttgcggaaat gggattcaaa
    20701 tgttatcgtt tttcgattgc ctggacacga atttttccaa atggagacga aggtactcct
    20761 aacgaagcgg gattagaatt ttatgatcag ctgattgatg agtgcttaaa atatgatatt
    20821 gaacctgtga tcacgatttc tcattacgaa atgcctcttc atttggcaaa agaatacggt
    20881 ggctggaaaa atcgaaaact gatcgacttc tatgaacgat ttgctcagac agtattagag
    20941 agatacagca gtaaagtcaa atattggatg actttcaatg aaatcaattc ggcctttcac
    21001 tttccagctt taagtcaagg attagtaaaa agcaatggag caggagagta ccaaaatatt
    21061 ttccaagcat ggcataatca attcgttgca agtagcaaag ccgtaaaaat cggccacgaa
    21121 ttgcgttcgg atatccaaat cggctgcatg attatctatg caacaactta cagcatcgat
    21181 gccaatccag tcaatcaggc agcaacaatg atccaaaacc aagaattcaa ttttttctgc
    21241 acggatgtcc aagtacgtgg agaataccct gcatacacag cgcgtaccca taaaaaatat
    21301 ggagtcgatc cggaaaaatt agagcaaacg gaaaaagact tccagttgct aaaagaatat
    21361 ccagtggact acatcggatt tagttattat atgtctacgg caatcaatga gactgatcca
    21421 caagcagcaa cttcagaagg gaacttgctg ggaggagtaa aaaatccgtt tcttgaggca
    21481 agtgaatggg gctggcagat cgatccagaa gggctgagaa tcgcattgaa tgaattatac
    21541 aatcgttacc agaaaccatt attcattgtt gaaaacggtc ttggagccat tgatcatatg
    21601 gaagaggatg gcacgattat tgatgattat cggatcgatt atttacgtcg tcatatcgaa
    21661 gcgatggcta atgcagtagc agacggtgta gatttgatgg gctatacgcc ttggggatgt
    21721 atcgatcttg tcagtgcatc aacaggagaa atgagtaaac gttacggctt tatctatgtg
    21781 gatctagacg atgaaggaaa tgggacactg aatcgatcaa agaaaaaatc ttttgattgg
    21841 tataaagaag taattgcctc aaatggcgta aacttgtaat taaagcagct gaatgaaaaa
    21901 gaacacactt ctcacatgtg atttgtgttc tttttttatt ttttatgtgc tattctttta
    21961 gtaatagtaa agcaaagggt gacgttatga aaaggacacg tgtactatac ttggaagtcg
    22021 cagataaaat taaagaagat attttctcag gaaaatatcc agtcggttcg atgttgccga
    22081 cagaaagtga attagaagaa ctgtttcaag tcagcaaaat cactgtccga aaggcaatcg
    22141 aactgctggc atcagatgaa tatgtcgcaa agaaaagtgg tcgtgggacg acggttctaa
    22201 gcaatcgtcc ttacaatcga ttatccaaag cggcaagctt tacgcaaatc ttggagaact
    22261 cccgatatga agtccggaaa gaaacgctgg atttgcaatt ggtccatata aagaaggaag
    22321 atcctttgtt ttcctttttc ggtgagcaag ctgtttgttt taagcgctta tattatttga
    22381 acaatcagcc ttatatttat tttgttcatt atcttccaca agaaatgatg caattcagca
    22441 gagaagaatt tggcaaagaa tctttgtatc gtttgctgac gaaaaaagga tatactattg
    22501 actcattttc tgatgatttc tcggcagtat ttttaacaga agaagaacaa ggaattctga
    22561 aaacagacgc acagatcggc atcaaacgga tacggaaatc gtctacgcaa attggggaaa
    22621 tgattgaata ttcggaggcg gtctaccata cggagctgca tccttaccat attgattatg
    22681 aaacataaat aaaaaaagag gttgtgaaaa agctgccctg catcaagtaa taagaacagc
    22741 caaacaaaaa tagcttctca tatttttcgt ttggttaggc ttattaccgc agatacacgg
    22801 ctgtttctgg attaccattt attctggata agggggtgtg gcacgatttt cagaaggaat
    22861 ctatgaacca atcactgtat tgattttagc ttcgatggta accccattcg gcttgacgat
    22921 cgcttatttc ttagggaaaa tcattcgtaa aaatatactc aatcgtcaag aaatcgatac
    22981 attgaagacc gcttttccta tggggatctg tcagatcaca gagggatgtt tccctatcgt
    23041 attgaacgac ttggcacgca atgtcatagc aacgggagtc ggtgggacag taggtggcgg
    23101 attaagcatg ttttggggcg cagatagccg tattccggca tcgggaatgt ttgcagtcgc
    23161 tacgatgacc agaccatggg cattcattgg tgcattgtta gctggttctt ttgtcacagg
    23221 aataaccatt ttattattga aaaaaccagt agatccgaat gcagaaatca tccaagaaga
    23281 aaaagaggaa gaagacatat cttgggatga tttgacaatt agttaggaga ggcagaatgg
    23341 attacaagaa aaaagtacaa tagatgtacc ttgagacagg aatggtatga aagaatcaga
    23401 gttagaaaga atcgaatata cagattttgg tttaggagcg atcgaaactg tccagagcat
    23461 cggcaccctc cttgaaatga cgatgaagga aaaatgagaa cctttcgttg tcgaaagggt
    23521 ctggtatacc ttatgtcgaa ggaaaggaaa caaaaaaact ttcctgtact attccaaaaa
    23581 ggaaagaaag ttattataca gtaaaaaaag aaattattct tcatgctaga gatcagtaca
    23641 cgttcgagcc caatatcaaa cactagttcc aggcaggcgc aacaggtgcg gttatcactg
    23701 aattttcttc cagcagtgac gattcaagtg atatttttac aaatccagct atttatcgtt
    23761 aacaaaaaga tttttaggag aagctgatga acaaaaatga tcaaattttg atcgtttagt
    23821 tcgtcggctt ttttatttag agaaacatca tttatcagtg aaacataaca cgagaacaaa
    23881 atgatttttt cgttaataaa agaaacaagt atttgttgtt taaaataata cacgttattg
    23941 gcatatagga cgaaatccca gtatcttcta taagtaagtc atttcatatc gatgaaaaca
    24001 cgttatttat ttttgtttta tctataaaat ggctgaaaaa tgattttttt ctaaatacta
    24061 tatatagtgg cgtctatcct atataccact aaaaaactac aaaatctagt cttttatttt
    24121 aaaaaaacac gtgtagaatg aagatagact tttgagttag ggagtgtttt tttatgaaac
    24181 ttactgtttt ttgcggttcc cgttttggta ataaagaaag ttacaaattt attgcgcaaa
    24241 cgttaggaaa atacatggca caagaagaaa tcgaactggt ttacggtggt tcatactccg
    24301 ggattatggg agtgattagt aaaacagtac tggaaaataa cggaaaagtc acaggtatct
    24361 atccgaatgg gctttttgaa actgaattgc ctggaaaaga tgttactaca tttattccta
    24421 cagaaacgat cgatgaaaga aaggtattat tatttgaaaa gggagatgct gtcctcgttt
    24481 tccctggagg tctaggtaca ttggaggaat tctcacaact tctttcttgg atagcaatcg
    24541 gtctgacgcc cgacaagcca atcggaatat tgaatattgg cggttattac agcggcttgc
    24601 aacaattatt agaaactttt gcaaaagagg attttatgga taaaaaatgg ttggatcaag
    24661 taatcttttc caacaatcca ttggaactgg tcaatgaatt acgagcagta tctattaaaa
    24721 atcagttatt attgaaggag gcaaaataat gagtcaaata tatttagcag gaccattttt
    24781 ttcagaggag caaatcgatc gagtaagtcg tatcgaaaaa gcgttggagg aaaacaaaac
    24841 agtcacaagt ttctactctc cacgtcatca ccaagaaagc aattatgaac tattcagcgc
    24901 tggatgggcg caggaagtat acgaaaaaga tatggaagaa ctgacaaatg cagaatttgt
    24961 tgttgctatc cttgactttg agcatcaaac aatcgatcca ggaacggctt acgaattagg
    25021 tgtggcaact atgttgaaaa aaccgatgat cattgtacaa gaagagacgg tacctacgaa
    25081 cttgatgatt acacaaagtc tccatacgta tttaaaatca gaccaagctg tacgtgaata
    25141 tgattttgaa acattgcctg ttgaaactta cgtaggcgag tacttataga agaggaaggg
    25201 ttgtatgtca gtgattttga tttcaggaac gattggtgca ggtaagagca gtttgacgga
    25261 tatgcttgca aaagagattg attctaaacc attttatgaa aatgtcgaag ataacgaagt
    25321 attgccgctc ttttattcaa atcctgagca gtacgctttt ttattgcaaa tcttcttttt
    25381 gaacaagcga tttttagcaa tgaaaaatgc tttagtgaac gatgacaatg tgctagaccg
    25441 atccatctat gaagatagcc tgttgttcca tctaaacgct gatttaggtc gggtaacgga
    25501 tatcgaagta cagcagtacg atagcttatt agatacgatg ctaaacgagt tagatgatgt
    25561 tgctccaaaa aaacggcctg atttgatggt ccatatcaaa gtttctttgg acacgatgct
    25621 agaacgtatc aaaaaacgtg ggcgtgacta tgaacagcta gaaagcgatg agacgttata
    25681 tacctattat gaaacgttga acacccgcta taatcaatgg tatgaagatt ttgatgtatg
    25741 tcctaaaata caagtggatg gggataaatt cgattttgta gaaaatccag aagatgcaaa
    25801 aaaggtgatc cgtcagatcc aagaaaaatt agctgaattg gaaggaaagc ctgctggaaa
    25861 atattttacg gataaccagc atgcaaaagg tcaagaatta ggctaaaaat aaaaaaccaa
    25921 acgacgggaa agaaaa
//
LOCUS       DARPZF010000037        23734 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.038, whole genome shotgun sequence.
ACCESSION   DARPZF010000037 DARPZF010000000
VERSION     DARPZF010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.038"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            257..532
                     /locus_tag="SLE65_001878"
     CDS             257..532
                     /locus_tag="SLE65_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449171.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            545..2623
                     /locus_tag="SLE65_001879"
     CDS             545..2623
                     /locus_tag="SLE65_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HEI8449172.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            2783..4669
                     /locus_tag="SLE65_001880"
     CDS             2783..4669
                     /locus_tag="SLE65_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEI8449173.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            4681..5628
                     /locus_tag="SLE65_001881"
     CDS             4681..5628
                     /locus_tag="SLE65_001881"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEI8449174.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            5648..6175
                     /locus_tag="SLE65_001882"
     CDS             5648..6175
                     /locus_tag="SLE65_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEI8449175.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6238..6891)
                     /locus_tag="SLE65_001883"
     CDS             complement(6238..6891)
                     /locus_tag="SLE65_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEI8449176.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            7023..7865
                     /locus_tag="SLE65_001884"
     CDS             7023..7865
                     /locus_tag="SLE65_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEI8449177.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            8023..8919
                     /locus_tag="SLE65_001885"
     CDS             8023..8919
                     /locus_tag="SLE65_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEI8449178.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            8922..9635
                     /locus_tag="SLE65_001886"
     CDS             8922..9635
                     /locus_tag="SLE65_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEI8449179.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            9655..10173
                     /gene="msrA"
                     /locus_tag="SLE65_001887"
     CDS             9655..10173
                     /gene="msrA"
                     /locus_tag="SLE65_001887"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEI8449180.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            10170..10397
                     /locus_tag="SLE65_001888"
     CDS             10170..10397
                     /locus_tag="SLE65_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEI8449181.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            10549..11100
                     /gene="lepB"
                     /locus_tag="SLE65_001889"
     CDS             10549..11100
                     /gene="lepB"
                     /locus_tag="SLE65_001889"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEI8449182.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(11183..11683)
                     /locus_tag="SLE65_001890"
     CDS             complement(11183..11683)
                     /locus_tag="SLE65_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HEI8449183.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(11962..12360)
                     /locus_tag="SLE65_001891"
     CDS             complement(11962..12360)
                     /locus_tag="SLE65_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEI8449184.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            12620..13480
                     /gene="ylqF"
                     /locus_tag="SLE65_001892"
     CDS             12620..13480
                     /gene="ylqF"
                     /locus_tag="SLE65_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEI8449185.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            13473..14240
                     /locus_tag="SLE65_001893"
     CDS             13473..14240
                     /locus_tag="SLE65_001893"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEI8449186.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            14296..15153
                     /gene="dprA"
                     /locus_tag="SLE65_001894"
     CDS             14296..15153
                     /gene="dprA"
                     /locus_tag="SLE65_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEI8449187.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            15275..17353
                     /gene="topA"
                     /locus_tag="SLE65_001895"
     CDS             15275..17353
                     /gene="topA"
                     /locus_tag="SLE65_001895"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEI8449188.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            17322..18698
                     /gene="trmFO"
                     /locus_tag="SLE65_001896"
     CDS             17322..18698
                     /gene="trmFO"
                     /locus_tag="SLE65_001896"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HEI8449189.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            18896..19801
                     /gene="xerC"
                     /locus_tag="SLE65_001897"
     CDS             18896..19801
                     /gene="xerC"
                     /locus_tag="SLE65_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HEI8449190.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            19838..20386
                     /gene="hslV"
                     /locus_tag="SLE65_001898"
     CDS             19838..20386
                     /gene="hslV"
                     /locus_tag="SLE65_001898"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HEI8449191.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            20400..21800
                     /gene="hslU"
                     /locus_tag="SLE65_001899"
     CDS             20400..21800
                     /gene="hslU"
                     /locus_tag="SLE65_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HEI8449192.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            21818..22609
                     /gene="codY"
                     /locus_tag="SLE65_001900"
     CDS             21818..22609
                     /gene="codY"
                     /locus_tag="SLE65_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEI8449193.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            22691..23566
                     /locus_tag="SLE65_001901"
     CDS             22691..23566
                     /locus_tag="SLE65_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HEI8449194.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
BASE COUNT         8215 a         4093 c         5000 g         6426 t
ORIGIN      
        1 tttttgtcgc agccccattt ttttgttgtg ataaaagaac aagaaaggca ggaatgggaa
       61 agtaaacatc cttttgtcag aaacttttat ctttcttaag ttttacttga tatctgatac
      121 tatttggaat agaatgaggc gttgaaaaat ttatggaaat ttctaactag caataaacga
      181 tgaaacaatg aaatattttt catccaaaaa gaactttgct ataatgatgg aagtttgtgt
      241 ataggagatc tggaaaatga gagagagttt tgaacaacaa aaaaaactgt tgcatgatcg
      301 ctatggcgcc ctttcgatgg atgaccgccg tcaaatactt tgtaagttgc gtaaaagaaa
      361 tatattgatg tatcgtcagt tggaacgtct gaaacatgat ctgcttcgtt tggagtcaaa
      421 acgtgtacag tgtgaattag aggggaacca aacacaggtt gaagtagtcg aaaccaaaat
      481 tttaaagaaa aaagaacaat ttttaaaaat gcttacacaa aataaaaaat aaaggggatg
      541 gacgatggaa tttgctgagt tagttattgt atttgcagta acgatcacct tatcgaacat
      601 agctagccgc attttgccaa tgattccagc tccactgatc caaattttcc ttggagtggt
      661 attaggtctg acagagtggg gacaatcaat cgattttgaa cctgaattgt tcttagttat
      721 gattattgca ccattgttat ttagagaagg agaaaaagca gatatttctt cgattctcaa
      781 aaatttcggg acaattttgt tcttggcatt tggaggagtc attttgaccc ttgtcggggt
      841 aggtgcgacg ttatcattcc tgttgccaag tgtcccactt gctgcctgct ttgcttttgg
      901 agcagcgtta ggtccgacag atgcggtagc agtcagttct ctttctggac gagtgaatat
      961 ccctaaaaag gcgatgcata ttttggaagg agaaggtctt ttgaatgatg catctggtgt
     1021 tactgccttc cagtttgctc ttggtgcgct gatcaccgga tctttttcag cagtaaacgc
     1081 ggggatgagt ctagtagttt ctagtattgg gggagctttg atcggctttt tgcttgtctg
     1141 gttcaaacaa aaaataattc atttgatcga aaaagcatca gcacaagatg tcacagggta
     1201 tctgctgatc gaacttttgc ttccttttct agcctatgta ttggcagagg catttgatgt
     1261 atctggaatc attgctgcag tggcagcagg tattctccaa gcttctggtt ttaggaaaat
     1321 ctctgtgttt gatgcagaat tgtcgagctt gtcccacagt acatggacaa ctattgcttt
     1381 tacactgaat gcattagtat ttatattttt aggaatcgaa ttgacgcaag tgttctcgcc
     1441 agtatgggga gacggtttat atccaaacgg tcttttatta gcgattatcg tattaatctc
     1501 tgtcatgctt tttgtgatca gattcatttc tatcagtctt ttttatgtat tcaaagatgg
     1561 cagtaaaaag ttcaaaaaac agttgaacga gatcttgatc ttaacatttg gcggtgtaaa
     1621 gggaacagtc agtttggcta cgatttttat tttgccattt tcaatcaata atatgatgtt
     1681 ttaccagcgg tctttgcttt tgtttctgac ggcgggtgtc atcttagtga ctttggtcat
     1741 agggatcatt gtcttgccta tgctgacgga aacagaggaa gcgaaaagca cggatttgaa
     1801 tgctttgatg attttagaag aggtcgttga agttttgcga aaagaaataa aggaaattga
     1861 tcgtaataca aaagaatttt tagccactga agcagtgata gaaaattatc aagaacggat
     1921 acgtgatctg tacttggaag atttaaccga tgatgaaaag caagaagtac aagaaataca
     1981 agcactgatt ttgtcgatcg aacgggatgg attggatgaa agttatcgtt cgggcaagct
     2041 ttcttctaat ggttatcgtt tttactcccg ttttctttct cgattcgaac attctatcac
     2101 aagccagatt ttgtctttta tcggcttttg gttcattgtt gtccgtaggt taatgcgaat
     2161 cgttctccat ccgaaaatgt tttggcaaag aagatatgct gatcgtcaga catttattag
     2221 tgatgaagat atccaagaaa tcagagagac atatcaaaaa aatactcagt tgattattga
     2281 aagtttagat aacttgactg atatttatga tgaaacgatg gttcaatttt ttatccagca
     2341 acgcaaactt gaaggaataa aaatgaactc ggggaatttg atttcttcgt ggatgatcca
     2401 gcaagatagt ctgtttacga aaaaaatgct aagaggttat tatcttgaaa gaaaaatcat
     2461 tgatgaatac gaagttgctg aaaaaatcac gacgttttct gcgaacagct atcgcaggaa
     2521 tatcaatttg ttagaatctt atacgatgaa caaaccatct gataactttt ctttccgatt
     2581 tgcgtttcga gcaaagtcaa aaaaaacgag tccaataaaa taaaaaggta aaaattttca
     2641 agttttataa aaaacaaaac atatcagaac aggatcgaat cggtcctgtt ctttttttga
     2701 gaacacaaaa agaacaaata ccaaaaaaat tttcctgaag ttcactattt ttatgataca
     2761 atatccaaga taaggaggga acatgttgaa agaattaaaa gtaactgacc tcaaaaaaac
     2821 ttatggtgaa aaagatttgt ttgaccagat ttcttttttg gtccacgaaa aagaccgtat
     2881 cgggttgatt gggacgaacg ggacgggtaa aacaagtctc ttaaatatta ttgccggtat
     2941 cgatagcagc gacggtgatc ggcaaacagt gttttatcca actgattacc gtattggtta
     3001 tctttctcaa gcagctgaat tttccgatga attaactgtt ctccaagcag tctttcaagg
     3061 aaacagcccc ttgatccaaa ctgttcgagc atatgaggaa gcattgatcg aactagggga
     3121 aaacggagaa gaccctgatg tgcaaaaacg ttatgctaaa gcagaagaac aaatgaataa
     3181 agaagatgct tggactacag ataccaacgc aaagattatt ttgcaaaaat taggaatcag
     3241 tgaattagat aaaaaaatca gtactttatc aggtggtcag aaaaaacgag ttagtctggc
     3301 gcaagtgttg attgatgaac ccgatttact attactagac gaaccaacaa accatttaga
     3361 ttatgaagcg atcgagtggt tggaaaacta tttgaaacaa taccgtggcg cactattgat
     3421 ggttacccac gatcgttatt ttctagatag agtagcaaac cgaatcttcg aactttcatt
     3481 tggaaaatta tacgagtata aaggaaatta tgaagcttac gtcttagaaa aagcagaacg
     3541 tgatcgtgta gaagtagaac aagaagaaaa gcgcaagcgg ctttataaac aggaattagc
     3601 ttggatgagg gctggcgtac aggcacgtgg caccaagcag caagcacgga tcaaccgttt
     3661 cgaagatcta aaggagaact tgtaccaagt aaaccaagaa gatgatttag agctgaacct
     3721 agcgacacaa cgtttaggga aaaaagtact ggaaatcaaa gatggcagtt accgtataaa
     3781 tgaccaaaca ctgctagaac atttagattt attgattcaa tctcgggaaa gactaggtat
     3841 tactggtaaa aatggtgcgg gaaaatcgac attgcttaat attctagctg gcagaattcc
     3901 cctggatagc ggtacaatgt ctatcggtga aacggttcat cttgcgtatt atacacaaga
     3961 aaatgaagaa atggcaccag ataaacggat gattgcttac ttacaagaag ctgctgaaga
     4021 agcaaaaaca gcagatggca gtcaaatcgg agtagcagaa ttacttgaac gatttttatt
     4081 tccaagattt atgcatggga cactgatagg caaactttca ggcggagaaa aacgccggtt
     4141 atttttgttg aaactgctga ttcagcaacc taatgtttta ttattggatg aaccgaccaa
     4201 tgatttggac atagcaacat tgacgatttt ggaagattat tttagaagtt ttccaggtgc
     4261 tgtgatcact gtttcccatg accgttattt cttggacaag gtagcagata agttattagt
     4321 attccaagga aacggaaaac aagaacttta ttacggaaac atgtccagtt atttactgaa
     4381 gcaaaaagag acccagcagc ctgctgaaaa agcgaaacca aaaatacaga gcaaggaacc
     4441 tgctgaaaag aagaaattat cttacatgga acaaaaagaa tgggaaacga ttgaagatga
     4501 gattgcagaa cttgaagaaa aaatctcatt gctccaagaa gagatgaatc atcaaggaga
     4561 taatttcact cgattacaag aattgcaaaa cgacgtatct gaaacagaag cacaacttga
     4621 agaaaaaatg gcacggtggg aatacttgag tgaatgggta gaagattagg aggaaaaagg
     4681 atggaacaag cgtatcttga cttaggaaga aaattgttgg aagaagggca tcgtaaagaa
     4741 gacagaacag gcacaggcac attaagctta ttcggatacc aaatgcggtt tgatctgcaa
     4801 aaagggtttc ctttgttaac aacgaaacga gtaccttttg gattgatcaa aagcgaattg
     4861 ctttggtttt taaaaggaga tacgaatatc cgctatctat tacaaaataa aaaccatatt
     4921 tgggatgaat gggcatttga acgctacatc aaaagtccag actataatgg accagatatg
     4981 actgattttg gccatagatg tttgacagat cctgaattca atgaagaata taaaaagcag
     5041 agcaagcttt tttgcgagaa gatcctaacc gatgattcct ttgctgaaac atacggcgat
     5101 cttggacaca tctacggcta tcaatggcgt cactgggaaa caaaagacgg tggctttatc
     5161 gatcaaatca aacaagtgat cgaagcaatc aaaaagactc ctgattctag aagattgatc
     5221 gtttctgcat ggaatccgga agatgttcct agcatggctt tgcctccttg tcatacgatg
     5281 tttcaatttt atgttcaaga gggacggcta agctgccaat tgtatcaacg cagtggggat
     5341 gtgtttctag gcgttccgtt caacattgca agttatgcgt tgctgactca cctaattgca
     5401 catgaaacag gtttagcggt tggcgaattt gttcacacat taggagatgc tcatctttat
     5461 atcaatcata tcgaacaaat gaaagaacaa ttgagccgag aaatacgcgc atttccgact
     5521 ttagttttga atcaggaaaa gcagtcagta tttgattttg agatggaaga tatccaatta
     5581 gaaggatatg acccacatcc ggcgatcaaa gctcctatcg ctgtttagaa tcagaaagga
     5641 tgagaaaatg ttagctgcaa tttgggcaca ggatgaaaac ggattgattg gaaaagaaga
     5701 ccgtcttcct tggcgtttgc caaatgatct gaaattcttc aaacaaatga cagaagcaaa
     5761 tacactagtg atgggacgaa aaacattcga agggatgggt agccgtccgt tgccgaatcg
     5821 tcagacgatt gttttgacga gagattcttc ctataaagca gaaggcgtgc atgtcatgca
     5881 tagtgtggaa gacgtgcttg ctctggaaaa agaaacagac ggtatctttt tcatcgctgg
     5941 agggtcagct gtttatcaag aatttctgcc attttgtacg atattatacc gtacagtcat
     6001 ccatcatgta ttcgatggag atgcttattt tccacctgtt gactggtctg attggtcact
     6061 gatcaatact agtcaaggag aaatggatga aaaaaatcgt tatccgcatc aatttgaaac
     6121 gtatcagcgt aatgagaatc ctgtaaaaag cgggacaggc gaattgacga tataaaaaag
     6181 ctatggatag actagctgtt atttagagct gtcccatcca tagctttatt ttttttatta
     6241 agtaaagaat aaaacagaga agtacataaa acctgcacct aacataacaa acaaatgcca
     6301 aacaacatgc atatagcgga tagaattcaa gctataaaag aatgcgccta tcgtgtaaga
     6361 aagcccgcct gctaccatca aaataacacc agtcattcca agagagtgat aaagaggaac
     6421 agcagccacg acacagagcc accccataaa aatatagatg atcgtagata cttttgatac
     6481 tctctcccgt ttatgcaacg tcaacgcttt atatataatg ccaagaatcg caaacaacca
     6541 gattaataca aataaagtcc aacctagcca tcctcggata ctcagcaaac aaaaaggagt
     6601 ataacttcct gcaatcaaaa gaaaaatcga actatgatcg aatacttgga acaccttttt
     6661 tgcttttgta aaaatcaatg aatgaaacaa agtagacgtt aaaaataaaa gaatcatcat
     6721 cgatccatag atagcataag agacaatatg gagggaggaa tgcaagtggg caccttttac
     6781 taaaagaacc actagtcccg cgatactcaa tccagtccca attccatggg tgactgcatt
     6841 aaacacttca tttaatattt catacgttcg attaaatttc gttttttcca tgaaaacggc
     6901 tcctttacta ggtgtaatta atgaaaaatc attatttgtc tgttatacta aaaatagaaa
     6961 ttgtcttaca tgtagtttaa catgaataag gcatcttgtt aaagaaagag agagagaaaa
     7021 taatgacaaa tgtaaaaatc gtaacagatt cttcatgtac gatggaaaaa aatgtacgcg
     7081 atgctttagg cattcgtgtc atgccgctat ccatcatgat cgacggaaca gtatatcccg
     7141 atgatgacca actagacggc gaaagattta tggaaatgat ggcgaaagca aaaaatctgc
     7201 ccaaaacaag ccaaccacca attggagaat tcatctcgat gtatgatgag ctaggagaag
     7261 acggcagtga agtgatttcg atccatatga caaaaggctt gagtggaaca gtagaagcag
     7321 caagacaagc cagtaatcta acaaaaacga aagtaacggt tatcgacagt gataccactg
     7381 accaaggatt atcttttcag gtaattcgag cagctgaatt agcaaaagaa ggtaaaacag
     7441 tagagaaaat ccttgaagaa gtcaaaaaag tacaagacaa tacaaaatta tacatcggaa
     7501 tatccacact agataacttg gtaaaaggtg gaagaatcag ccgaacaact ggtttgctgt
     7561 ctagtgtttt gaacatacgc gtggtgatga atttcgccca ttctgaatta atccctgtaa
     7621 ctaaggggcg aggaaagaaa acgttcgata aatggtttaa taatttgaaa aatgaactga
     7681 aagaattgcc aaatgtgcga caaatcggta tttcacatgc ggatgcaaaa gaattggcgc
     7741 aagaattcaa agagggtttg caagaattat tcccggacat gcatatccct gtactgcata
     7801 cgaatccggt tatcgctacg catactggta aagacgcgtt tgcaatcatg tattatgtag
     7861 attagtcgaa aagaggataa gccctcagcc tgaaaggctt gcagcttatt ctctttttct
     7921 ttataaaatt aggaaaataa ttgttttctt ttttcataaa gactaccttt ttgataaaat
     7981 ttttgataac attagaacca atcgaataca agaggtgaaa aaatgaaatt aacgaaacga
     8041 catttgatcc tcgttttgtt cccattatta attgcgatca tcatctatgc aggtttagct
     8101 gcttctatac cgaaagctgg cccactaatg aaaccagtaa ctactgtgag agaagatcca
     8161 aataaaaaag aaaaacttca ctacatagct atcggagatt cgctgactga aggagtagga
     8221 gatcaaacca agcaaggagg attcgttccc cttgtcgcaa atgatctaaa agaccgttat
     8281 aatttgaccg cggttgaaac agaaaactat ggtgtaaatg gtgaacgaag tgaccagatc
     8341 ttaaagcgag taaaaacaaa agaagaaatt cgaaacaata tcaaaacagc tgattttatc
     8401 acactgactg ttggcggtaa tgatttgatg aaagttatcc aaaataattt attcgggtta
     8461 acggtcaatt cctttaaaaa gccactgaaa aactatcagg aaaatgtcac agaactattg
     8521 gaagaatttc gatccctcaa taaaaccgca cctatttaca ttttaggcat ctacaatcca
     8581 ttttatttga actttcctga gatcactgac atgcagacaa ttgttaacaa ttggaacaaa
     8641 ggaacagaaa cggtgacaaa aaaaatgccg aactgctact ttatcccaat caatgatttg
     8701 ctttatcaag gattgaatca ggaagtaggt gtcacagaag aaggaacaga tcaaacaact
     8761 agcacgacag aaaatctaaa tggcatcaaa aataatgtgc tctatgaaga agatcatttc
     8821 catccaaata atttaggtta tcaattgatg gcaaatgcag tgagagatca gctgatcgag
     8881 acacaaaacc aatggttaga gaaggaggat gatcaataaa catgaaaaca agatctgacg
     8941 tatcttcaaa caaaacaaag aaaacaaatt actggaaatt cgccttcctt atccttcttg
     9001 gggtagtact tggttcgacc gtatttttag gcagccgtat ttttgctaat cgggaaccag
     9061 aactcccaga aataccagct cttacggaaa gacaaggaga tcctgtctta acgatcaatt
     9121 caaataaaga aaaagtcaat caaatcatca gctttttcct tagtgagtat caaaaagata
     9181 gtgatattga atataaattt tatttggaaa atgaagcact actcaatggt actttcgaag
     9241 tactaggttt tcctatcgat ttctatttat attttgatcc gtatgtgatg gaaaacggaa
     9301 atgtccaact aaaagctaga agtctttcta tcggaacatt gagtttgcca atcaaagatg
     9361 tgatgaatat gatcaagaga aactataaat taccagattg gatcgaagtc aatacagatg
     9421 atctgactat catgcttagg ttggatcaat tccgaatgca aaacgggatg tatattaaag
     9481 cagataaaat cgacttagta aatgatgaca ttcggtttag tctatatttg ccaaaagata
     9541 cctctgatgc ttcaaacaac tcaaatacca acaaaactag caccagcagt actgaaagca
     9601 agacaaaaga aaataaaaaa tcatcggatg agtagtatta gagggggaat cataatggaa
     9661 cgagcaatat ttgcaggagg ctgcttctgg tgtatgatcc agcctttcga cacgcttcct
     9721 ggtatccata cagtgatgtc aggatatact ggagggcatg taccagatcc gacttatgaa
     9781 caagtaaaaa gccaaacgac tggacataca gaagcagtgg agattatcta tgatccaaca
     9841 ttgatttcat atgaacaatt agtagaactt tactggcagc aaactgatcc aactgacgct
     9901 ttcggacaat tcgaggatcg cggtgacaat tatcgcccgg tgatctttta tttgacagaa
     9961 gaacagcgga tcattgctga aaaaagtaag aaacagttag ctgaaagtgg acgtttcgaa
    10021 cagccaatcg ttacaaaaat cgaaccagcc caaccatttt atctagcaga agaagaccat
    10081 caagagtatt ataaaaagca tcctgaaaat tttaaaagaa accatgcacg ccgggctgcc
    10141 tttatcgaag aaaattggag gaacgaaggg tgaatcgaag cttttttcat tatttaatga
    10201 cactgcgagg cggtggcaca catgatgctt tatctgtttt cgctacagaa gccggtaaag
    10261 acatccaatt tcctaagcac agctctagct acgaagaaat ttctaattat ctggaactga
    10321 atgtcgacta tttgccgtcc atggatatct ttgacgaagc atgggaaaaa tatttagaaa
    10381 ataatcatga catataagag atagttttgt actttatgat caaaaaagtt ttttgtccaa
    10441 tagcctaatt gaaagaatta tttttatttc agctatctag tcgcattttt ttgatatttt
    10501 tcttataata aagaaagaat gaaaaaaaga gggatggatt gatagagatt gacaaaaaaa
    10561 caacgctata ttaatcgctt ctggcttgta ttcaaatact tacttgtttc tgtattcctt
    10621 gcgttcatgt tgcggggatt tttattcatc ccggtaccag tggaaggcaa ttcaatggaa
    10681 aacgtgttga agcaaggtga tatggttgtg atggaaaaat tttcggagat cagacgattt
    10741 gatattgttg tttttcaatt agcagatggc acgatttata tcaaacgagt aatcggtctt
    10801 ccaggagaaa atgtcagcta ccaaaatgat caattgaaga tcaatgggaa agtagttaag
    10861 gaaccttatc taactaaaaa cctgaaatca gatcatgcaa atgcatccta tacgacggac
    10921 tttacactac aagagctaac gggacaatcc aagcttccgg aagataatta ttttgtactt
    10981 ggagataatc gaagagtttc aaaagatagt cgttcgtttg gcacgatcaa taaaactgat
    11041 attctaggta aagcaagatt tgtctattat ccacttgatg aaataaaatg gatccagtga
    11101 gaaacaataa agcgtgcagt ctgttgagac tgcacgcttt attgtttaat ccaaaatcag
    11161 tttactacct tagtacgtaa aatcaaacag ctcgtttaaa cacttttcta gcctctaaag
    11221 ttttgataaa tgaataaaca accattattt gaatagggat ttggatcata ttcctgatga
    11281 atctacctag aaaaattact ttgaaatctg caccaaacaa aacagacatc agccaagaat
    11341 tgataaaaag gctgactggg atcataatca ataattgggc agcgatgacg gaaggcaggt
    11401 ttatcttttt atgatataaa aataagccat taataaatcc accaaggaaa gccgtgataa
    11461 gaaaagcagc ttgaaacgtt cctgaaccaa atatcgtgaa atttaaagtg ttcgacaaca
    11521 tttcaagcaa accagcccag atcggtccat atagataacc cataagcgcc atacttaaaa
    11581 atccgaatgt gatttgaaaa taagcaggac caatcgctat cttgtataag atgacatcaa
    11641 gggctaataa aagagcagag gtcgacaaca atcttgcatt catttcgggc aatctaaaaa
    11701 cgtcttttgc aatcaaagtg ttcaaaatat tctctccttt gtcagttaat aataaaagga
    11761 taccataaaa tcaccaatgt gtcatgacac attggtgatt tacatacact ggcatctaac
    11821 aattaaaaaa agggtgagaa gactgctttt ataaactgta aaaaagagat tgtacgaata
    11881 aaaaaaatag aggcggagaa tacttatcgt atcatccgcc tttgtttttt tgttataaaa
    11941 aacgtcagat tagttatctg cttacatctt catccatacg ggttctaatg tatttccgtc
    12001 tagatcttgg acttctaatg aaaacatttc ttcttcaggc attcccatat ctacttcgtg
    12061 gaaagtacca ccattttctt ttgcaatttg agcaaatttt tttacttcat ccgcattttc
    12121 aacactaaac gaaatcaaag caccacttgt ttttttatta tcagctattt ctttatcttt
    12181 tataaatttt ttataaaaat catgagagag aagcattatc caaaaagtgt catcccatac
    12241 cattgaacca gcttcttcag tagaaaattc ttcatttttt ttaaaaccca gcttttcata
    12301 aaaagcaacg gaacgattga catcagcaac aggaaaatta acaaaaacca tactattcat
    12361 ttgtttcgtc tcctttctgt tttgttcgtc tatcatctct tatttaggaa acgctgtcaa
    12421 aaatttagat tcatatatag aaaccaaaat aaaaatttgc atcatcaaaa aagtgaagat
    12481 gtgatagaat gaggactggt tcactttcac ttaactaata gatggaattt ctttataata
    12541 aaaaagtgaa tttatattga aaaagaaaaa aacaagtaaa gccggggaat attccggtat
    12601 gaaaggaatg gagagaacaa tgaccatcca atggtttccg ggacatatgg caaaagcccg
    12661 acgagaagtt tctgaaaaaa tgaaatatgt ggacatcgta tttgaattgg tagacgcacg
    12721 attaccttta tcttctcgta atccaatgct agatcagatc attcagcaaa aacctcgcct
    12781 tgttttattg aataaagcgg atctggcaga tccacaacag acaaagctgt ggcaagaata
    12841 ttttcgtaaa caaggccatc ttgcattagc tatcacggca caagaaagta aaggaattaa
    12901 aggtctagta cctgcggcta aagaagcatt gaaagaaaaa cgggcaagag atgctgctcg
    12961 ggggatcaag cctcgcgcta ttcgggcaat ggtcttaggt attccaaatg ttgggaaatc
    13021 tacgttgatg aatcgactag taggcaagaa aattgcacag acaggaaata agcctggcgt
    13081 aacaaaaggt cagcagtggc ttcgtttagg taatgagttg gaattgttag acacaccagg
    13141 gattttatgg cccaaatttg aagatgaaga aatcggcaaa aaactagcgc tgacaggcgc
    13201 gatcaaagac cagcttgtcc atttagatga tttagcgatt tacggattag acttttttgc
    13261 ccgatattat tcaggaagaa tcagcgatcg ttatggttta tcaatcgagc aagaagaaaa
    13321 attggcaccg gaattactga tggatattac agcaaaacgt gggtataaag aagactatga
    13381 tcgtggcagc gaattagtcg tgcatgatat tcgtcaagga aaacttggac gatacacact
    13441 ggatcgttgc gaagaaatgg agcaaaaaag tgatgactga atccatccaa agtatcaaag
    13501 aacgattgaa aagcatacag agaatagatg atcctacact agaatcatta agaaatgatc
    13561 cacgcaaagg cgtgcagcaa gcactggctt cttttgaacg acgattgaaa aaggaagcat
    13621 taattaagga aaaatatgaa gaaatgtttt gctttgaaaa gcaagggtac gcacaaggtc
    13681 accaatggat tgccggcatt gatgaagtag gaagaggacc attagctgga cctgtcgtgg
    13741 cagctgcagt tatcttgccg aaaaatgaga tcatattagg gctgaatgac tccaaacaat
    13801 tatcagagaa aaagcgagaa cttctttatc aacaagttca agaaaaagcc ctggcaatcg
    13861 ggatcgggat cgttgatcag cagacaatcg atgatgtgaa tatttatgaa gcaagtaaat
    13921 tagcgatgat ccaagcagta gaaaaattgt ccattgtacc aagctatttg ttgatcgatg
    13981 cgatgacctt ggatttgcct attcagcagg aaaaaataat caaaggggat gcacgatctg
    14041 tgtcgattgc tgctgcaagt atcattgcta aagtatatcg agaccaattg atgaaagaat
    14101 atgacgtgct ttatcctgga tatggtttct cgcataatgc aggttatgga acaaaggaac
    14161 acttagaagg acttgaacga caaggaatta cgccaatcca tcgtaaaagt tttgcacctg
    14221 taaaaaaata tttacaataa aaaacagccg cttttacgta tcttattaga aagagagacg
    14281 aaaggcggtt ttatgatgta tcaaatagaa gaaaatttat tgaaacttgc ttatacaaaa
    14341 ggaatcagta gtcaaggaaa atgggcactt gctaactgga tgatgcagta tccttataaa
    14401 gaaatcggat ttgaagacat cattaagata ggtaaaataa ccaaacaccg ggagctgttt
    14461 cgcaaaagtt ggcaggaaat tcacgctaac tggggcaaaa tccaatcgaa acagtcgttt
    14521 atcacttgct ttgatcccaa atatccccct cagctgcttc acttgaccta tccgccaatt
    14581 gtactgtttt ataatggtga tctatcttta ctttcttgta acatgttaag cgttgttggt
    14641 ggaagacaca cttctgcttt agccaaaaaa acagtttatt atttactaaa accagtgata
    14701 gaagctggat atgtgatcgt cagtggctgc gcgaaaggga tagatacata cggtcaccaa
    14761 gcagcaatct ctcatggtgg acggacaatc gcagtcattg gaacagggat agagcaagtc
    14821 tatcctgctg aaaatcgtga cttgcaagag gtgattgcaa atgatcatct tcttttgagt
    14881 gaatatcctc ctcaatccgg cccgaaaaag cattgttttc caatgagaaa tcggattatc
    14941 gcagctttgt ctaaaggaac atgtgtcttt gaagccaaga aaaaaagcgg ctctctgata
    15001 acagcacagc aagcattgga tcttggaaga acagtttttt ctgttccagg aaatatttta
    15061 acagaacatt ctaccggatg tcatcatttg atccaagacg gtgcagtttg cacggtttcg
    15121 ggtgaagata tcttggcaga atttaaagaa taacaccata cttttcattt gcttttcttg
    15181 acaaacgttt tctgaatgga tatgattagc tacgatttgt atgaatcctc ttttaatagt
    15241 aggaacacga caatggaaag gagtccattc agtaatggcg tataaatatt tagtgattgt
    15301 agaatcacct gcaaaagcca agacaattga gaaatatctt ggacgaaact ataaagtaat
    15361 ggccagtgtt ggccatataa gagatttacc gaaaagtaaa atgggtatcg attttgaaaa
    15421 caattatgaa ccccattata tttctatacg cggaaaaggc gatgtcatca aaagcctgaa
    15481 agccgcagca aaaaaagctc aaaaagttta cttggcaagt gacccggata gagaaggaga
    15541 agcgattgct tggcatttag cgtacctact tgggttggat ctgaaagaaa aaaatcgggt
    15601 ggtcttcaat gaaatcacaa aagacgcagt caaagcagct tttaaggaac caagaacgat
    15661 cgatgtagat ttagtagatg cacagcaagc tcgtcgtacc ttagacagaa tcgttggtta
    15721 ttcgatcagt cctattctct ggcgtaaggt caagaaaggg ttaagtgcag gacgtgtcca
    15781 atctgtcgct ttaaaaatta ttattgaccg tgaaaaagag atccgagaat ttgttccaga
    15841 agaatattgg agcatcgacg gtaattttaa aaaagctcgc aagaaattca aagcaaattt
    15901 ctggggaatc gacggtaaga aaaagaaatt accagatgca caaagtgtaa aagaagtcac
    15961 tgctagaatt gatggaacag acttcgaagt taaaaaagta gaaaagaaag agcgcaaaag
    16021 aaaccctgcg aatcctttca ctacaagtag cctgcaacaa gaagctgccc gtaagttaaa
    16081 ctttcgaaca agaaaaacca tgatggtagc acagcaatta tatgaaggaa tcactttggg
    16141 taaacaagga acagtcggct tgattacata catgcgtact gattctaccc ggattgccga
    16201 tacagcaaaa gcagaggccg cagcatttat tgaagatacg tatggaaaag aattttctag
    16261 acatgatcac cgaaagatca aaaatgctca aggcgcacaa gatgcccatg aagctgtgcg
    16321 tccaacgagt gtgcttcgta caccagatga actcaaacaa tatttagata aagatcaatt
    16381 gaaactttat acattgatct ggtcacgttt tgtggctagt cagatgacac cagctatttt
    16441 agatacaatg aaagtgacat tagaacaaaa tggtgtcatc ttcattgcga acggttcaaa
    16501 aatcaaattc aaaggattca tgcaagtgta tgtggaaggt agagatgacg gcaaagaaga
    16561 gaaagaaaat attcttccag aacttgaaga aggcgatgta gtccaatctg ttgatattga
    16621 accaaaacaa cattttactc aaccaccagc acgttttagt gaggctacgt tgattcgtgc
    16681 actagaagaa aacggggtag ggcgaccttc cacttatgca ccaacacttg atacgatcca
    16741 aagacgctac tatgtaaaat tgacacaaaa aagatttgag ccgactgaac taggagaaat
    16801 tgtcaattca ttaatctgtg aattcttccc tcaaatcgtc gatatccatt tcacagcaga
    16861 aatggaagga gatttggata aaattgaaga aggcacggaa gcgtgggtca aagtggttga
    16921 tcgtttctat aaaccgtttg aaaaagaact gacgaatgcg gaagaaaaaa tcgaaaaaat
    16981 tcaaatcaaa gatgaaccag caggattcga ttgtgatgtc tgtggacatc cgatggtgat
    17041 aaaattaggg aaatatggga agttttatgc ttgcagtaat tttcctgatt gtcggaatac
    17101 gaaaccaatc gtaaaagaaa tcggtgtgac ttgcccagta tgtcatgaag gacaagtcat
    17161 tgaacgaaaa tctaagaaaa acagactatt ctatggttgt tcccgtttcc cagaatgtga
    17221 attcacttct tgggataaac cagtgggcag aaattgtcca aaatgtgacg gatatctggt
    17281 cgagaagaaa gtcaaaggcg gtaaacaagt agtctgtgta aatggagatt acgaagaaga
    17341 catccaaaaa taatagaaaa gaggttcttt cattgaaaat ggtaaatgtt gttggagcag
    17401 ggcttgccgg aagtgaagct gcttggcaga tcgcacaagc aggagtccct gtccgtttat
    17461 atgaaatgcg tccagtcaaa tcgactgagg cgcatcacac aagtaatttt gctgaactag
    17521 tatgttccaa ttcattaaga ggaaacagtt tggctaatgc agtagggtta ttgaaagaag
    17581 aaatgcgccg attgaattcg gtagtaatca cttcggcaga tgaaacagca gtgccagctg
    17641 gtggtgcctt agctgttgac cgcgattctt tttctgaaac aattacccga aaagtcaaag
    17701 agcatccatt agtaacagtg ataaacgaag aaattactga aataccggaa ggaatcaccg
    17761 tagtagcaac aggacctttg acttctcatc cattagcaga aagcatcaaa gcattcaatg
    17821 gttcagatgg tttttatttc tatgatgcag ctgcaccaat cgtagacaaa gctacgatcg
    17881 atatggataa agtatatttg aagtcccgct atgacaaagg agaagcagct tacttgaact
    17941 gtccgatgac agaagaggaa ttcaaagctt tccatgaggc actaatcaat gccgaagtgg
    18001 cagaacttaa atcttttgag aaagaaaaat attttgaagg atgtatgcca attgaagtaa
    18061 tggcacagcg aggattcaaa acgatgcttt tcggacctat gaaaccagtt ggattggaag
    18121 atcctaaaac tggcaaacgt ccttatgctg ttatccagct gcgtcaagac aatgctgcag
    18181 cttctttata caacatcgtg ggctttcaga ctcacttgaa atggggcgag caaaaacgtg
    18241 ttttccggat gattcctggg ttagaaaatg ctgaattcgt tcgctatggt gtgatgcacc
    18301 gaaacagctt tatgaattcg ccagaattgc tgaaaccgac ttaccaatca acgaaacgcg
    18361 aagatctgtt ctttgcaggt cagatgactg gtgtagaagg ctatgttgaa agtgcagcga
    18421 gcggactact tgctggaatc aacgccgcac gcttagcaaa agaaatggaa ccagtcgagt
    18481 ttccacaaga aacagctatt ggaagtatgg cttactacat tactcatgcg gaaggaaaac
    18541 atttccaacc gatgaatgcc aactatggtc tgtttcctga actgccagag cgcattcgag
    18601 acaaaaaagc aagatatgaa gcaattgcac aacgagcttt aaaagctaat gaggcaataa
    18661 aaacagaatt agaaaaaact gcaatcccaa atgagtaagg aaactccatg aagagggtga
    18721 gacggatagt ctcgctcttt ttcttgcgtt tttcttaaga atttctcaaa caaaatgtga
    18781 ggaattgcgc caattgtgaa caaacttaga aatattggtt aaattctgac aatttatttg
    18841 tctttttata aacgctgtgc taaattattc tctgggacaa aaggaaggtg agaaaatgac
    18901 agaagccacg tgggaacaaa aatttttgcg ttatttgatt gtcgaaagag gatattcaga
    18961 aaaaacgaaa gaagcatatg aagaagacat tctccatttc aaacattttt tggaggaatc
    19021 tggagacgct gatctgctga aggcggaata ttttacggtt cgtgtctatt tgagtgcatt
    19081 agctgatcat cgtcctagct atagcagaaa ttctatcagt cgcaagatag ccagcctacg
    19141 ttcgttttat cagtatcttc tcaaagaaga agtgataaaa gaaaatccat tttcttacgt
    19201 tcatctcaaa aagaaaaatt tgagactgcc acgttttttt tatgaaaatg aaatgcaagc
    19261 actttttgac agcgtagcag gagatagtcc tttggatttg aggaaccgcg ctttactgga
    19321 agtcctttac gggtcaggca tccgtttaag tgagtgtagc agtttgtcgg tatcagacat
    19381 tgattttgat tcagaggtca tgttgatcca tggtaaaggg aacaaagaga gatatgctcc
    19441 tctaggttct tttgctcaag atgctctgca agaatatttc agggaaggcc gccaggtatt
    19501 gatgacaaaa tatcacgaag agcatgatat cgtttttgtg aatcatcatg gaaaaccaat
    19561 cacgcctact ggaattgaat atgtcttgaa tcaaatgatc aaaaaaagca gtttggatag
    19621 tgatatccat cctcacatgc tgcgccatac atttgctact catttattaa ataatggggc
    19681 agatttgcgg acagtccaag aattgctagg acatgccaat ttatcgacta cccagatcta
    19741 tgcccatgta acaaaagaaa gtttacaaaa aaactatcgt tctttccatc caagagcgta
    19801 aaaataagga aaagaacaaa tttaggagga aacaaacatg gtcgaatcac catttcattc
    19861 aaccactatc tgtgccgtcg aaaaagacgg gaaatttgct atggctggag atggccaagt
    19921 aacaatgggt gaatctgttg tcatgaaagg cactgcaaag aaagtacgac gtatctacaa
    19981 tggagaagtt gttgtaggtt tcgccggaag tgttgcagat gcgtttactt tagaagaaaa
    20041 atttgaaggc aaactaaacg aatataacgg gaatctacaa cgcgcagctg tcgaattagc
    20101 tcaagaatgg cggacacagc aatctatgca aaaacttgaa gcgatgctga tcgtaatgaa
    20161 tgataaagaa atgcttcttg tttcaggtac aggagaagtt atcacaccag atgatggtat
    20221 cttagctatc ggatcaggag ggaattttgc gttggctgca gcccgagcaa tgaaaaacta
    20281 tgctcaaaac gacatgagtg cgaaagaaat tgcagaaaat gcgttaaata ttgccgcaga
    20341 tatctgtatc tttactaatc ataatattat cgtagaagaa ctgtaagagg tgagtagata
    20401 tgtatgaatt aaaacaaaca ccaagacaaa tcgtaagtga attagatgaa tatatcgtag
    20461 gacagcacgc agcaaaaaaa tctgttgccg ttgctttgcg taaccgctat cgccgtttgc
    20521 agttagatga aaaaatgcaa caagatatta caccaaaaaa tatgctgatg atcggaccta
    20581 caggggtcgg taaaacagaa atcgcacgac gtttggcaaa aatcgtcaat gcaccatttg
    20641 tcaaagtcga agcaacaaaa tttactgaag tcggttatgt cggaagagat gtagaatcaa
    20701 tggttcggga tttagtagaa aatgcgatcc aaatcgtaga aaaagagcag tacagccgtg
    20761 tatacacaag tgctaaaaaa aatgcagaaa aacgtttggt aaaaatcttg gtacctggta
    20821 tcaaaaaaga acagaaacaa tccactaatc aatttgaaca aatgatgaat ctttttaatg
    20881 ctagtcagca aaataccgct gaaccgcaag aagaagtgac agaagatatt cgaatcaatc
    20941 gccgtacagt cttggaacaa ctacaaaagg gtttactgga tagtcgtgaa gtaaccattg
    21001 aagttgaaga ccaaaagaaa cctgcaccaa tgatgaacaa tggattggag caaatgggga
    21061 tcgacctaaa tgaaactcta ggtgctttga caccgaagaa aaaagtggaa cggacggtaa
    21121 cagtcaaaga agctttagag ttattgatca aggaagaatc agcaaaatta gtcaaggatg
    21181 ctgatatcca tagtgaggca atcaaattag cggaagaaag tggaattatt tttatcgatg
    21241 aaatcgataa gatcacttct aaatcacagc aatctggaga agtatccaga gaaggcgtcc
    21301 aaagagacat attgccaatt gtcgaaggtt cacaagtaaa cacaaaatac gggatcatcc
    21361 aaacagatca cgtcctattc attgcttcag gagctttcca tttgtctaaa ccaagtgatc
    21421 taattccaga acttcaagga cgcttcccga tacgggtaga attagatgat ttgacagctg
    21481 aagattttgt gaagattctg accgaaccaa ataatgcttt agtaaaacaa tacgtcgcgt
    21541 tgatcggtac agaaaatgtg tcagttacgt ttacaaaaga agcaattgaa cggatcgctc
    21601 aaatcgcttt cgatgtcaac cgtgacacag ataatatcgg cgcacgcaga ctgcatacca
    21661 ttttggaaaa actactagaa gatctattat ttgaagcacc agatatgcaa atgggagaaa
    21721 taacgatcac agaagcatat gtggatgaca aacttggctc aattgcggca aatgaagatt
    21781 taagtcgcta tattttataa aaaatcggag gacgacaatg acagacttgc taacgaaaac
    21841 ccgcaagata aacacacttt tgcagcaaaa gaatactttt gacatgcaag cagatttgcc
    21901 ttacgataaa atggctgtca cactaggtgg tattcttgac agcaacacct atatcatagg
    21961 aagtgacgga gtattactag gttataatga acgtcacgat gtgaacaatg aacgaatcaa
    22021 aacaatgttt gttgagaaac aatttcctga atcttatact gatacagtgg cacagttgat
    22081 gaaaactgaa gctaatatcc caattactag tgatattact gcatttccgg tagagtcaag
    22141 agagaaatat ccatttggtc tgacgactgt cgttccgatc tttggagctg gcgaacgttt
    22201 gggtacgatt atcttatctc gtatggaaca atcgtttgca gatgacgatc tagtcttagc
    22261 agaatatgga gctacggttg tcggtatgca gatcctttat cagaagtctc gaagcatcga
    22321 agcagatgta cggagtgcaa cggctgtcca aatggcaatc aacacattat cttatagcga
    22381 attgaaggct gtacaagcta tctttgaagc attggatgga gatgaaggtc gtctgactgc
    22441 ttctaatatt gccgatagta tcggcatcac tcgttctgtg atcgtcaatg ctttacgaaa
    22501 attggaatca gctggaatca ttgaatctcg ttcgttaggc atgaagggaa cttatttaaa
    22561 agtattgaat tcccgtttta aagacgagtt agcaaaacac agttattaga agtaagggga
    22621 ctggggcaga tagaaatgtt tgttccagcc ttcccatttt aaaaagtaag tcgaagttgg
    22681 aggaatggca atgactgtta ttattcaaaa tgaccagctg atcgccgaaa tcgctgaaca
    22741 cggtgcggaa ttgatcagtc tgaaatcaaa agaacatggt ttagagtata tctggcaagg
    22801 tgatccagcg tattggggca gacatgcacc ggttttattc ccttttgttg gacgtttaaa
    22861 agatgatcag tatgtttatc aagggaaaac atatcaaatg gggcaacacg gatttgctcg
    22921 ggatatggat tttgaagtca ttgaacatgg acaagaaatg gctagtttca tcttaaggag
    22981 tacgccggag acattagaaa agtatccatt tgattttgaa ttagtgatca gctatgaatt
    23041 aggaggagac ggcatcacgg ttcattatca agtggcaaat accggtgaaa aagaaatgtt
    23101 cttttctatc ggtggacatc ctgctttcaa tgtacctctt gaagaaggat tgtcatttga
    23161 agatttctat ctggcatttt ctccattgaa atcaagatta cgcctaccat tgaaaggccc
    23221 attcatcgat atggatcaaa agacgttagg tcagacaaat acgaatctgg ctttgaatcg
    23281 tgaacttttt gagcaagatg ccttggtttt tgaaacaagg ggtctaaatg cgtacgccat
    23341 tcgaagtgaa aaatcttccc atagcgtaac tttaagctat aaagatatgc cttatgtagg
    23401 gatctggtct ccttatccaa aagaagcgcc tttcgtttgt atcgaaccgt ggtgcggaat
    23461 cgctgacacg gtgaacagta gtggaaactt gatggaaaaa gtagggatca atcaactagg
    23521 tgcccatgaa atcttcaaga caaaatattc catcacagtg aagtaagagg ttgtgaccga
    23581 gaagttagca gggaacaccg tttaccaagg tgtgtaaaaa agctatcctg taagtaataa
    23641 gggagtgtga catcgatttg tggctctttg tcaataagga ctgatgagtt gtgcaaaatc
    23701 aaatctgagt cagaatgaac cacattctgg ctca
//
LOCUS       DARPZF010000038        23578 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.039, whole genome shotgun sequence.
ACCESSION   DARPZF010000038 DARPZF010000000
VERSION     DARPZF010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.039"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            44..676
                     /locus_tag="SLE65_001902"
     CDS             44..676
                     /locus_tag="SLE65_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HEI8449195.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(678..1583)
                     /locus_tag="SLE65_001903"
     CDS             complement(678..1583)
                     /locus_tag="SLE65_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEI8449196.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(1668..2327)
                     /locus_tag="SLE65_001904"
     CDS             complement(1668..2327)
                     /locus_tag="SLE65_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEI8449197.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            2643..3587
                     /gene="mvk"
                     /locus_tag="SLE65_001905"
     CDS             2643..3587
                     /gene="mvk"
                     /locus_tag="SLE65_001905"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEI8449198.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            3580..4557
                     /gene="mvaD"
                     /locus_tag="SLE65_001906"
     CDS             3580..4557
                     /gene="mvaD"
                     /locus_tag="SLE65_001906"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEI8449199.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            4570..5655
                     /locus_tag="SLE65_001907"
     CDS             4570..5655
                     /locus_tag="SLE65_001907"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEI8449200.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            5652..6716
                     /locus_tag="SLE65_001908"
     CDS             5652..6716
                     /locus_tag="SLE65_001908"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEI8449201.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(6965..7768)
                     /locus_tag="SLE65_001909"
     CDS             complement(6965..7768)
                     /locus_tag="SLE65_001909"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEI8449202.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(7788..8630)
                     /gene="kduI"
                     /locus_tag="SLE65_001910"
     CDS             complement(7788..8630)
                     /gene="kduI"
                     /locus_tag="SLE65_001910"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HEI8449203.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(8646..9653)
                     /locus_tag="SLE65_001911"
     CDS             complement(8646..9653)
                     /locus_tag="SLE65_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEI8449204.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(9660..10304)
                     /locus_tag="SLE65_001912"
     CDS             complement(9660..10304)
                     /locus_tag="SLE65_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEI8449205.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(10404..11162)
                     /locus_tag="SLE65_001913"
     CDS             complement(10404..11162)
                     /locus_tag="SLE65_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HEI8449206.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(11289..12440)
                     /gene="fucO"
                     /locus_tag="SLE65_001914"
     CDS             complement(11289..12440)
                     /gene="fucO"
                     /locus_tag="SLE65_001914"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HEI8449207.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(12522..12833)
                     /gene="rhaM"
                     /locus_tag="SLE65_001915"
     CDS             complement(12522..12833)
                     /gene="rhaM"
                     /locus_tag="SLE65_001915"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HEI8449208.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(12835..13680)
                     /gene="rhaD"
                     /locus_tag="SLE65_001916"
     CDS             complement(12835..13680)
                     /gene="rhaD"
                     /locus_tag="SLE65_001916"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HEI8449209.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(13694..14950)
                     /gene="rhaA"
                     /locus_tag="SLE65_001917"
     CDS             complement(13694..14950)
                     /gene="rhaA"
                     /locus_tag="SLE65_001917"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HEI8449210.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(14947..16407)
                     /gene="rhaB"
                     /locus_tag="SLE65_001918"
     CDS             complement(14947..16407)
                     /gene="rhaB"
                     /locus_tag="SLE65_001918"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEI8449211.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            16560..17429
                     /locus_tag="SLE65_001919"
     CDS             16560..17429
                     /locus_tag="SLE65_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HEI8449212.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(17555..18454)
                     /locus_tag="SLE65_001920"
     CDS             complement(17555..18454)
                     /locus_tag="SLE65_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8449213.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(18619..19443)
                     /locus_tag="SLE65_001921"
     CDS             complement(18619..19443)
                     /locus_tag="SLE65_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HEI8449214.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(19454..20749)
                     /locus_tag="SLE65_001922"
     CDS             complement(19454..20749)
                     /locus_tag="SLE65_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HEI8449215.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(20765..21244)
                     /locus_tag="SLE65_001923"
     CDS             complement(20765..21244)
                     /locus_tag="SLE65_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HEI8449216.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(21250..22278)
                     /locus_tag="SLE65_001924"
     CDS             complement(21250..22278)
                     /locus_tag="SLE65_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HEI8449217.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(22295..23401)
                     /locus_tag="SLE65_001925"
     CDS             complement(22295..23401)
                     /locus_tag="SLE65_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HEI8449218.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
BASE COUNT         6779 a         5200 c         4239 g         7360 t
ORIGIN      
        1 tcccgcttct ttgctatact aaagaaaaac gaggtgaacc cacatgaaaa aaatcgaacc
       61 tattccacct tctcttcctc ttcttacaaa gggagagttt tatttagaag atgaggagat
      121 cttctctggt cttctgatca acgggggtga ccaaagctat ctcgatgcca aaaatatggt
      181 attaagagag agtcatatcc aaaaacttac gatgcaaaaa acagttttac gtcattttga
      241 atgcagtaat gtcatttttg aaaaatgtga tttttccaat ctggagtgga ttggtggcag
      301 tttccaccaa gtcgtgtttc atcaatgtaa attaacaggt acgaattttg ccgaaagtta
      361 tcttcgagac tgtactttca ctgattgtat tgcttcgatg gcttccttta gtagtacaaa
      421 cttgaaagct gtctccttcg atcattgtca attagaagac agcgaatttt atgaggtcac
      481 ttggaaaaac ctttttttgt ctgacaatca gttgaccggt tcgaactggt ttcgaacttc
      541 tctgaaggga ttagacttta cgactaattt cttcacagca atcgctttat ctcaagattc
      601 tttggcggga ctaatcgtca accaagagca agcacttgtg atcgcccaag cccttggttt
      661 gcagatcaaa gactagatca acgaatccgc cgccacagtg caataagcat ccaaatagat
      721 aagaccaaac tgatgatcaa ggcgattccc catccgaaaa cggaatgggt aaagggtaac
      781 tggagattca ttccgaagaa tcctgtcaca atagttggaa cggtcaagat cagcgaccag
      841 accgtcaaaa atttcatcgt gtcattcaag ttgttattca gcaaattatt ataagtgcca
      901 gagagctggt ctaaaatctg cgaagctaag ttcgtcattt caactgcttg tcgtgcttcg
      961 atcagcgcat cgtccaactc ttctttttcc ttttctgaca acttgcgata aatagccaat
     1021 gccttgattt gttctaaaag tactacattt tgttttgttc ctgtaactaa gtaaaccaaa
     1081 ccgatctcta aatctgaaag ttgcagcaga ttcttgttcg ttgttttttc tcttaatttc
     1141 agattaagcc gctgacgttc actattcact tcctcgatta aaggaaaaaa ggaatcagaa
     1201 atcaaaaaca atgtacgaaa caataaactg tatacactca tgtctggcat tcgttccaaa
     1261 agcgatcgaa ttagtcgaat cacgtactcg gtattcggcg tggtaaatgt aaacaaaccg
     1321 tcttctttta aaataaaagc gataggacta gtttcataat gattatcgac tttttgctgg
     1381 tgcggaacat ttgatacaag cagtaacgct tcatcaaaag aatcgtactc tacgcgcgcc
     1441 cgttcatttt tatctagaga ataagtcagc atctcgtcac taatgccata ttcttctttt
     1501 aagtttttaa cagctagcac atcgttttgc tgtacattga tccaaaaatt acggtcttga
     1561 ttaaaatagt gtttttcccg catactctat cctcctgaca tttgtttcca gtataaagaa
     1621 aaaagtcgct caaataaagg tttacccttt atttgagcaa ctgtaaatca aatggctact
     1681 ttggtttggc gaatctctgc taatttttct tcgatcattt tcaagacttc ttcttttgct
     1741 tgaggatctt ccacaaaatt atagcggtct ccatcgattt ggatttttgg actttctttg
     1801 tattcttcat accattgatc gtaacgtctg ttcaattctt tgtaataatc gtatagactt
     1861 ggatcaaagg acaattgttc atacgaacga ccacgttttt cgatacgctc caacatcgta
     1921 tcaaaagata cacgaatatg aactaataaa tccggatgtt ttttatgggc agcataggga
     1981 agttcttcca tcatgttttc cagcagttca tcatacacac gaacttctgt ttctgttgct
     2041 cttcctagat ctgcatttag atggaaaagc agtgaatctt cataaatcga acggtccaat
     2101 acattattgt catctttcat tgcttgtttg atgcttgcaa aacgtttatt caaaaaataa
     2161 atttgcagca aaaaagcata ctgttcaggg tttgcataaa ataagggcaa gacttcatta
     2221 tcatcaatcg attcataaaa tgcctgacta tcaaagtgtt cagccatcat ttctgttaaa
     2281 cttgattttc cggcaccaat tgtacctgct aaaacgatca cgctcattta cctccagctc
     2341 acttcatcac taaatattgt gtttaactcc aaccttttta aatatacccc caatatctag
     2401 tagtgtcaat tgtatttttt tctagtcaaa gaagaaaaaa agtcaaaaaa ttcttaagaa
     2461 aaaagtgttt tttctttaga aaacgtattc ttagttttac ttctgagatg gttttagtaa
     2521 aataaaggag gaatgttttt tgagaccctt agtggacaaa aaaattcgtg aagcagcgca
     2581 actcgttttg ggcgctttat tttttgctta aaaatcactt ttacgtgaga aggagttaga
     2641 ttatggcaaa ctatggccaa ggagaatcaa gcggaaagat catattgatg ggcgagcacg
     2701 cggttgttta tggagaacca gcgattgcct ttcctttcta tgcaacaaaa gtcaccgcat
     2761 tccttgaaga gctggatgca atggacgatc aactggtttc ttcctactat tcaggaaatt
     2821 tagccgaagc tcctcatgca ttaaaaaata tcaaaaaatt attcattcac ttaaaaaaac
     2881 agcatgacat ccaaaaaaac ttgcaactga ccattgaaag cacgattcct gctgaacgtg
     2941 gaatgggatc aagcgctgca gtcgccacag cagtcactcg tgctttttat gattacttag
     3001 catttccttt gtctcgtgaa atactattag aaaatgtcca gctttcggaa aaaatcgccc
     3061 acggtaatcc tagtggaatc gatgcagccg ctactagcag cttgcagccg atttatttta
     3121 caaaagggca tcctttcgac tacttttctt tgaacatcga tgcttttttg attgtcgctg
     3181 atacaggaat caaaggacaa acaagagaag ccgtcaaaga tgtcgctcac ctctttgaaa
     3241 cccagcctca tgaaactgga caaatgatcc aaaaattagg atacttgacg aagcaagcaa
     3301 aacaagcaat cattgaaaat tcaccagaaa cgttggcaca gacaatggat gaatcacaat
     3361 cacttctgga aaagctgaca atcagcaatg attttcttaa tctattgatc caaacagcaa
     3421 aagataccgg ggcattgggt gccaaattaa ctggcggtgg acgcggtggc tgtatgattg
     3481 cattagcaca aacaaaaaca aaagcccaag aaatcagtca agcacttgaa gatgcgggtg
     3541 ctgctgaaac ttggatacaa ggattaggag tacataccta tgtttaaagg caaagcacgc
     3601 gcatatacca acattgctct aatcaaatat tggggtaaga aaaatgaaga actcatcctt
     3661 ccaatgaaca acagcctttc gttaacattg gatgcatttt atacagagac agaagtcatc
     3721 ttttctgata gctatatggt agatgaattt tatctagatg gcaccttgca agacgaaaaa
     3781 gcaacaaaaa aagtcagtca gtttcttgac ctttttcgta aagaagccgg cctctcacta
     3841 aaagcttcag taatcagtca gaatttcgtt cctaccgcag ctggattagc ctcctctgcc
     3901 agcgggctag ctgctttagc aggcgcttgc aatactgctc ttaagcttgg attagatgat
     3961 ctctctcttt caagatttgc tcgacgcggg tctggttcag cttgccgaag tattttcggt
     4021 ggtttcgtcg aatgggaaaa aggccatgac gacttaagtt cttacgctaa gccagtccct
     4081 tccgattctt tcgaagacga tttagcaatg gttttcgttt tgatcaacga ccagaaaaaa
     4141 gaagtgtcca gcagaaatgg gatgcgtcgg acagtcgaaa catccagttt ttatcaaggc
     4201 tggttagatt ccgttgaagg ggatctatat caattgaaac aagcaatcaa aacaaaagat
     4261 ttccaacttc tcggagaaac gatggaaaga aacggactaa aaatgcatgg aacgacttta
     4321 gctgcccagc ctccattcac ttactggtct cctgacagct taaaagcgat ggatgcggtg
     4381 cgacaattga gaaagcaagg cattccatgc tactttacga tggatgctgg ccctaatgtc
     4441 aaagttttag tggaaaacag ccatttatct gaggtacaag aaacatttac caaattattt
     4501 agcaaagaac aagtaattac tgcacatgct ggtccaggaa ttgcgattat tgaataaagg
     4561 gagattttta tgattgaagt atctgcacca ggcaaactct atattgccgg agaatatgca
     4621 gttgttgaaa caggccatcc agcagttatc gctgcagtcg atcaattcgt gacagtcact
     4681 gtagaatctg cacgaaaagt cggaagtatc caatctgcac aatatagtgg gatgcctgta
     4741 cgttggacaa gacgcaacgg agaattagtt ttagatattc gggaaaatcc ttttcattat
     4801 atccttgctg ctattcgctt gactgaaaag tatgcacaag aaaaaaacat tcttttatcc
     4861 ttttatgatc tgaaagtaac aagtgagtta gacagttcaa atggccggaa atatggattg
     4921 ggttctagcg gtgccgtgac cgttgcaacg gtcaaagcct tgaatgtttt ttacgcgttg
     4981 aatttatctc agttggagat tttcaagatt gcagcactag ccaatttagc agttcaagat
     5041 aatggttcct gcggcgacat cgctgctagc tgttatggtg gctggatcgc tttctcaacc
     5101 ttcgaccatc cttggctcca agaacaagaa actcagcatt ctatcagtga gttacttgcc
     5161 ctggattggc caggtctatc cattgagcca ttgattgctc ctgaagattt acgtttattg
     5221 attggttgga cgggtagccc tgcctctact tctgatttgg tcgatcaagt tcaccgttcg
     5281 agagaagata aaatggtggc ttatcagctt ttcttaaaaa atagtacaga atgtgtcaac
     5341 gaaatgatca aagggtttaa agaaaataat gtaacgttga tccaacagat gattcgaaaa
     5401 aaccgacaat tactgcatga tttatctgca atcactgggg tcgtcatcga aacgcctgct
     5461 ttgaacaaat tgtgtaattt agctgaacag tatgaaggag ccgcaaaatc ttctggtgca
     5521 ggtgggggcg attgcggaat cgtaattgtt gaccagaaat ctggcattct tcctttaatg
     5581 agtgcatggg aaaaagcaga aatcactcca ctgccgttac atgtctatag cgatcaaaga
     5641 aaggaaaacc gatgaatcga aaagacgaac atgtttcact agctaaagcc tttcatgata
     5701 aacaaaaaaa cgaatttgac ttcgtacgga tcatccataa ccctttgccg caaatagcag
     5761 tttctgatgt cgatctaagt acacaggcag ttgggtttac actaagcagc ccattttata
     5821 tcaatgcgat gactggcgga agcgaaaaaa caaaaaaaat caaccaagat cttgcaatcg
     5881 tcgcaagaga agcagatttg atgattgcca ctggttcagt cagcgctgcc ttgaaagtcc
     5941 cttctttagc cgatacttat acgattatgc gacaagaata tcctcacggg aaaatcattg
     6001 ccaacatcgg tgcagggact tctgtcgaaa gagccaaaga agctatccga ttgtttcacg
     6061 cagatgcctt acagattcat ttgaatgcac ctcaagagtt ggttatgcct gagggagacc
     6121 gtgattttac caattggaaa gtacttattc aagaaactca aacagccatt gacgtccccc
     6181 tcatcgtaaa agaagtcggt tttggcatga caagagaaac gctcaatgat ctagctgctt
     6241 taggagttca tacagttgat atcagcggtc gaagcggaac aagcttcacc cagatcgaaa
     6301 acgcccgtcg ctccaagcgg gaactgagtt atttagctga ctgggggcaa tcgacagtct
     6361 cttcattgct tgaagcaaat gaagcagaca cttctatgga aatcctagcc tccggaggta
     6421 tccgcaatgc ctatgacata tttaaagccc tttgtctcgg cgcaaatgcc gtgggtactt
     6481 caggaaccgt actgacgcat ctgatgaatc acggcgtaga agaaactatt atactgatga
     6541 agcaatggca agaagagctt cgtctgcttt atactatggt cggcgcaacg aataccgcgg
     6601 ccctacacca acaatctctg atcttttccg gaccagtgaa ggattggtgc gaagcaagag
     6661 ggatcgactt agtgaagtat ggaagacgca cagaaaagag cgtgggacaa aagtaaagaa
     6721 cacttttgtc tcacgctcta aacacgtaca aacggcggaa gtaaaagcaa ctccttcgga
     6781 aataagctga aattcacaaa aatttgaaaa gcaattttcg tgaattcctt cttatttctt
     6841 ggagttaaat gcttctgtcc cagcctcttt tttcgaataa atgatgttta atcagctgtc
     6901 cttcggtatt cgttcaatcc gctgatttca caacctctcc actaaacagt gtactaaagc
     6961 tcttttaagg ttgttttccg atataggcaa gtatgcctcc gtccacatac aagacatggc
     7021 cgttaacgaa atcagatgcg ctagaagcca agaagacaga tggtccagcc aaatcgattg
     7081 gctcgcccca gcgtgctgct ggcgtacgtc caacgataaa ttgatcgaat ggatgacgtt
     7141 caccgttttc ttgtgtttcg cgtaatggag cagtttgcgg tgtagcaata taacctggtc
     7201 caattccatt acattggata ttgtattgac cgtattcaga agcgatgttt ttcgtcagca
     7261 tttttaatcc gccttttgcc gcagcataag cactgaccgt ttcgcgtcct aattcactca
     7321 tcatggagca gatattgatg attttaccgc cgcctttttc gatcatatcc ggaataactg
     7381 cttttgaaac gatgaatggg gcatttaaat ccacgtcgat tacttggcgg aagtctgccg
     7441 catccatttc gatcatcggt gtccgtttga tgatccctgc attgttgact agaatatcaa
     7501 ctgaacctac atcttctttg atctgttgaa ccatcgcttg aaccgcttct tcatcggtca
     7561 catcgcagac ataacctttt gcatcgatgc ctgcttcttt ataatgcgct ataccttcat
     7621 caactgattc ttgattcaag ttattaaata cgatttttgc tcctgctgta gctaaagagc
     7681 gtgcaatctc aaatccaata ccatagacag caccggtgac taatgctact tttccatcta
     7741 aacgaaacat atccatacta aattccatca ttttctctcc cttatgctta ttttaattga
     7801 tccatttgca ccatatccat gtctgtatag gtgatatttt ctccgcacat tgcccagatg
     7861 aatgagtaat tgcttgtacc tacacctgaa tggatcgacc agcttggcga aataatggct
     7921 tgttcattgt ctacaactaa atgttttgtt tcatctggtt tgcccatcat gtggaacaca
     7981 cgtgtatctt cattggcata atcaaagtag acataagctt ccatacgacg ttcatgtgta
     8041 tgacaaggca tcgtattcca agcgcttcct ggttctaaaa tcgtataacc catttgtaat
     8101 tgacagcttt cgcatacatt tggatggatg tattggtaga ttttacgttc attcagtgtc
     8161 aggccttcac cagtctccat tggttttact tggtcgatac tgatttttac atttggatat
     8221 ttatgatgag ctggaacaga actaatatag aatttagctg ggttttcagc atcttgagaa
     8281 gaaaatacaa catgtcgtgt ttcttttccg atatagtatc cgtcttgttt tttcatttct
     8341 tctttttgcc catcgatctc gatgaatcct ggtccaccga tattgatcac acctagttca
     8401 cgacgctcta agaagtaatc aacacctagt tctttgtcta atgtgatttc taattctttt
     8461 tcagtaggtg tcactccacc aaagatcatt cgatcgttgt gcgtataagt caaactgatt
     8521 ttccctggtt caaatacctt ttctactaaa aattcttttc tcaattgttc cgttgaataa
     8581 tgacggatat cttctggact gtgtgtataa cgtgtttcca tttcttgcat tttcttctac
     8641 tccttctatc gaatgatttt tccagagccg catgctaaaa attgtgcgac ttcttcttga
     8701 ctaaattggt tgcagtcccc atggatcgta tgcttcaagg cagaagctgc cgtagcaaaa
     8761 tcaatgattt cttgcggaga catattggat aaaatcccat ggagcacgcc acctgcaaaa
     8821 gcatctccgc cacctactcg atccacgatt ggggtgattc tatggacttg ggattccaca
     8881 tattcatggt tcatccacaa tgtccccttc aattcatttt cacttgctga atgaacggta
     8941 cgcttggtcg aataaaacac ctgaatattc gggaactttt cctgcatttt ttgataataa
     9001 taaattagag gttgttcttc tgcttctggc gctttctcga tacctaacaa ataaagagca
     9061 tccatttttc cagctgagca gatatctact aaaggtaaaa gctgatggat tacttcgctg
     9121 gcttcttgct gtgtccataa ttttccacga tagttgatat cgaagctgat caggcagcca
     9181 gctttttttg cagcttctat cacctgtttc gtcatttttt gccatttttt agacaaagct
     9241 ggggtgattc ctgaaacatg aaatatatct attccttgga ataactcctc tagcgaccat
     9301 tccaaatgat ccatttcagc aaaacttgat ccggcacgat catagatcac tgaggcggcg
     9361 cgttcgccac taccagtttc catataataa gtacctagtc ttgatccacc agataatacc
     9421 tgtttcgtat ctactccata acattgcaag tgctttttga ctgcttttcc caatgcgtta
     9481 tcaggtactt ttgtagcaaa aatcgcttca tgtccgtaat tagctaaaga aattgctacg
     9541 tttgcttccc ctccgccata atgggcagcg aatcgttcac ttgaatcgat acgggttccc
     9601 tgctctgtgg acaatcgcaa catgatttct ccgagtgtca ctacttttcc cataagcagc
     9661 tacctcttga tttctttcat ttttgctgca tactgttgcg cgacttccgt tactttgtca
     9721 aaatctcctg tagctgcggg tgctaaaagg ttcccaccta ctccgactgt tacgacacca
     9781 gcatcgaacc actctttcat attgtccaga ctcacaccgc cagttggcat gatattgact
     9841 tgaggcatcg gcgccttgaa ggcagaaatg atacttggtc cataagcgct tccaggaaat
     9901 agtttgacga tatctacccc gcttttcagc gctgttttga tctcggtaat agtcatacat
     9961 cctggtaagt aaggaatttg atacagattg cacatctctg ccgtttcttg atcaaaggaa
    10021 gggctaacaa tatactctgc gccagctaag atagccaagc gagctgtgac agcgtctaat
    10081 actgtgcctg cgccaatcac tatttctggt tggtctttgt agaatgacaa aagttctttg
    10141 attacttgat ctgcttgagg gactgtaaaa gtcaactcaa taccagttag accacctttg
    10201 atgattgcgt ggcaagcatt caaagcttct tctttgcttt ttccgcgtac caccgcaatc
    10261 actccggcgt ttttcaatcg agataaaata tcaatttttt tcatcttctc cacctatttc
    10321 ctatttagaa attttatttt ataacttgga aatctatacc catattatac ggcagaaaag
    10381 aaaaattgca aacgcttttt tcattatttt tgaattcttt gctcgatttc gctttttgtt
    10441 tgcttgaggg cactgattat ttgttctttt gtctcatctg ttaaacgata tttcggcata
    10501 cttacactaa atgcaccaat gatttgttcg tttttcacga ttgaggctcc tatacaaaaa
    10561 atatcacgtt cgatttcttc atcgtcaaat gcgatgtggg tttcttttac cgtttggatt
    10621 tcctttttca accgtaatgc attggtgatc gtatattctg tgtaagggat caacggatgc
    10681 ttttcaagat aatcagtgta ctgctcttca ctgaattctg ctaatacggc tttgcccatc
    10741 gcagaattgt ataatggtcg ggtgattccg atttttgaag acatgcggat cgtttgatgt
    10801 tttggatcta gtttgttcac gtacaagatc tcattgttgt ccaatacccc taagtggata
    10861 gtctcatcga tcttttgctg cagctgttct aaaaacggta aagtcaactc taccaaatcg
    10921 atttgttcaa tgtttttatt cgcgtagcga ataagctttg cacctaaacg atagtttttc
    10981 tctgaatttt tatttacgta gccgatcatc aacaaagtat ctagtatttt caagactgta
    11041 gaagaggtca ttcccacacc ctttgcgatc gtctgcaaag agacatcttg gttttccgct
    11101 aaatagtcta gtattttaga ggctttgatc aatacagttc cataaggctt tttattttcc
    11161 atataatatt ctcctatttc tttataagaa aaattatagc ggaaatacca tcaatttaaa
    11221 agagatatcc agatataaac taccatttct ctttacaggc aatttaatgt tgaagatccg
    11281 cttcgttttt acatcaaact ttgatataaa gcaatgattt cttctactgt cgtttctctt
    11341 ggatttcctg gtgtgcatac atctcgcaaa gcatcttctg caattgctgg aatatctgct
    11401 tcttttacac ctaattcaga aatggtttct gggattccaa ccgctttgct caaccgatcg
    11461 atctcaccac aagccgcttc tcttacatct tctaaagaca tttcagctgc tcctttaatc
    11521 cctagaacaa gagcgatctc acggtacttt tctccagtat attctttgtt atatttcatg
    11581 acagttggca aaagtgctgc acacgctacg ccatgaggaa tgttgtacca tgcacttaac
    11641 gggtgagcca tcccgtgtac cagtcctaaa ccgacatttg agaagcccat tcccgcaata
    11701 tactgtccta atgccatttt ttctcgccca ttttgatcgc catctacaga agcttccaaa
    11761 gaatggccga tgatttcgat tgcttttaaa tgcagcatat cagtcatttc ccaagcgcct
    11821 tttgtgataa acccttcaat agcatgcgtc atagcatcca tacctgttga tgcagccaat
    11881 tttttcggca ttcccatcat catatcgctg tcgatgaacg cgacgattgg gatatcatga
    11941 ggatcaacac aaacaaattt tcggtgattt acttcatctg tgatgacgta gttgatcgtt
    12001 acttctgctg ctgttccaga agtcgttggt atagctaata taggtaaaca tggatttttc
    12061 gtatcagcaa caccttctaa actaatgacg tctgaaaact ctggattcgt caaaataatc
    12121 ccaatggctt ttgccgtatc gattggcgaa cctccaccga ttgcgatcaa acagtctgcc
    12181 tctgcctctt taacaaaagc cactccatct tttacatttt ggatcgttgg attaggtacg
    12241 atcccgtcgt ataaagcata agcgattgct gctttatcta gaagttctgt tacttttgtt
    12301 gctataccgt gctcgatcaa tcctttgtca gtaatgacag ctgctttgcc gaatcctcgc
    12361 tgctgaaatt cagggacgat cgactcaatc gctccttttc caaaatacga tgtttcattt
    12421 aaaatcattc gattactcat tttctattcc tcctaatttg tattattttt cacaataaaa
    12481 acgaaagaac cccaagcaac cggttgccca gttgcttgtt gctacagttc aaagactggc
    12541 atcaattccc aactgactgg agaggcatct ggatttgtct ccatgatatc ttccatgtac
    12601 ttccaccatt tttgattgat agatgtattt gccatttttt cccataactt ttcatcttcg
    12661 atcactaagt aaccaaataa caaacttgta ctcggatcaa gatagatcga atagtcgatg
    12721 accccgtgtt cacgaagtgc tgtacgcatt tctggccaaa gttcatcatg tctttttttg
    12781 tattcttctt gtttttctgg gtaaactttc atgcaaaaag cttttttcac catgtcagac
    12841 acctgctttc gtatgaactt cctccaaata acctgctttt ggagtgacac caaacgcatc
    12901 tgctaaatgc cacaggtttt cgtccgtgat tgtttgcaag attggtcctt gcgctttgac
    12961 gtacgtatag acttctgctg ccttttctgc tgtctcgatc aaaccaaaga cttcatccat
    13021 gtcttttcct gacccgtaga ttccatgttg tggccataaa accaatcgag tttctttcat
    13081 tttttcagct gttgcttccc caatctcatt tgttcccgga accatccacg gaatgatgga
    13141 aattccttct ggaaaaacaa ctaagcattc cgtacacatt tgccatagcg tacgactaaa
    13201 ggaacgttcg tctaattcat gcgtaaaact catcgctaat agatgactag catggcaatg
    13261 cataacgatc cgattatctg ggtctacttc taaacgggcg atatgactca tgaaatgact
    13321 tggcaactcg cttgtaggaa ggcattcgtt ttccagcccc cacaaaagtt ccagtgtttt
    13381 gccatcttca gcaactcgaa cgattccaag attctcggca ggttcgctcg ctacattttt
    13441 aaaatatctt cctgaaccag ttacaataaa atagcatcct gctaaacggc tggcatcaaa
    13501 aatcatcgag atgcggcgga tcactttttc aggatccaag aacggtgtga tctcttcttc
    13561 ttttagtaaa taagaaatat tcccgccatt tctttcatcc catcccaagc gataaagatt
    13621 cgacgtcgtt tcgatcattt ctttcacata aggcgcttgt aaaatatcta tttttttcaa
    13681 tatagccaca ctcctatttt cttaattcca acacgtcttt ttgatattcc tggacttctt
    13741 ccagccaatc caaaccaact ggaacttgat ttttgtaaca gaaataattc catacatcgg
    13801 catacgggaa atctttcaat tcttccgtat aagccattct tgaagtaaag tcaaaagcca
    13861 gctccatttc tttcaatcgc tcaactggtt ccagcatagc tttcagcagt gctttttgtg
    13921 tatttctcgt accgatgacc caagcagcga tacggttgat cgttgcatca aagaaatcca
    13981 gaccgatatt tgttttttcc aacaattcgt tacggactaa ttctttagcg atttcctgca
    14041 attcatcatc catcaaaacc acatggtctg aatcccaacg cactggacgg gaaacatgca
    14101 acatgattcc tttgctgaat aaagctaatg aagataattt attggaaatc acttctgttg
    14161 gatgaaaatg tccagcatct agacaaacaa gtttgtcacg agtcaacccg taacccatat
    14221 aaaattcatg ggaaccgact gtataagctt cagcgcctaa accaaatagt ttgctttcta
    14281 ctgcatcttg tacataccgt tcatctaact cttctgtaaa aatttcatcg agtgattcca
    14341 ttaaacgttc ccgtggggta aaacgatcaa tcggattatc tttcatccca tcaggtaccc
    14401 aaaagttatt gatacttgtt tgcccagttt ctttcccaaa gtactccgcg attttgcggc
    14461 ttcttttccc gtgttcgatc cagtattcac gaacttcttt atctggatga gccaatgtaa
    14521 agccgtcttt catcattgga tgcgaaaaga aagtcggatt gaagtcaaga ccgatttctt
    14581 ctttttttgc ccactctacc catttttcaa aatgtttcgg ctcaatttca tttagatcga
    14641 cagattcttc tgtatccaaa tagatagcat gaaggttcaa tttgtgtttg cccggtatca
    14701 acgaataagc cttctccaga tcttgtctaa gctcttcagg tgttcgtgcg gctcctggaa
    14761 aattccctgt cgccatgatt ccaccggtca attcgccatc cggtgtcaag aaacctttga
    14821 catcatctcc ttgccagcaa tgcatagaaa ttttgatgtc ctgtatcttt tctagtacag
    14881 catctgtatc tacaccgata gttgcatatt tttcttttgc ttgttcgtaa tttctttcaa
    14941 tcgtgttcat acgattactc ctttgatttt attcacgtac cattccatcg tgttttgctt
    15001 attttcatct gggtaaaaag tttcacatgg aaacgactgt ttgattacat ttcttgcttg
    15061 ttctatattc gaaaactgac ctgtactgag catttgcatg gcaacattcc cgattgctgt
    15121 ggcttcacta ggtcctgctt ctacaatgat tccggcataa tctgctgtca attgattcag
    15181 tagacgatta ttcgatccgc cccctacgat gtgcagcttt tccaatttcg ttccagttaa
    15241 gtgttctact ttgatcagct cttgtgcgta acaaagagca agattatcat acacacaacg
    15301 agcgatagct cccgatgaga cagggactgg ctgctctgtt tcaaaacagt attgctgaat
    15361 ctcttctatc atatttgggg gattcaaaaa tcgagggtca ttgatttcca tcacttgctg
    15421 cagcggtttt tcttttgcag caagctctgc caattccgca taactgtact cgtactcttg
    15481 cattcgggca acttcctgga tcaaccacat ccccatgatg tttttcaaaa aacgcaccgt
    15541 gttatgggca ccccattcat tcgtataatt ttcagaaaaa gcattgcgag aaacattggc
    15601 gatctttgtt tcaatcccta aaagcgacca tgtcccactg ctgatataac cccaacgttc
    15661 tccttgacct ggcgttccta atacagctga cgccgtatca tgacttgcta ctgtgataaa
    15721 ggtcacatct ggcaaatcat attttgaaaa ttgttctttt tgcagatctc ctagtatcgt
    15781 tcccggctct gtcaatggtg gaaataattc cttcgagaca ccgatttttt caagaagttc
    15841 tatttcccat tcttttgtcc ctgcattcag cagctgcata gtagatgcat tagttttctc
    15901 cgtcaccatg ttaccagtaa agacataccc taaataatca ggtatcagta acaatttatg
    15961 tgcttttgcc aaattttctt tttcttcagc aaacaattgg aacaaggtat tgaaaggctg
    16021 gatctgaatc cctgtctgct catacaactt atctagagaa tagatttcag aaaactgttc
    16081 tactgctcca ttggtacgct tgtcccgata agcaatcgga tcatttatcc gatccccttg
    16141 ttcatcaatc agacagtaat cgactgccca tgtatcgatc cccgcaaaaa ggcgatcaat
    16201 ccctgtctgc tttaattttt caaatccaat caaaatctct ttgataagat aatcgatctt
    16261 ccagcgatcg tgaccgtctt tgttccgaaa gccgtttttg aaccggtgta cttcttccaa
    16321 gatcaaagaa ccttttgcat ccctcgtact tttcattagt cgtccgcttg atgcaccgat
    16381 atcgatggca acaaatgttg gattcatttc tccacctctt ttactttatt gttgattagc
    16441 actttattaa taaagcgtta tcatttatta acaatgctat cataatacag aatcttatat
    16501 tttgcttcac actattttgg tatataattg cattatcttg acaagttggg agtgtttaca
    16561 tggattactg ggaaaaagcc aaccactcat ggtcggaaga ctcaaaaaga gtgatcttga
    16621 cgcctacaca aagaagcagg aatttatttt tttatatcca agaaatcggt tacttcaaag
    16681 caccaatccc ttactatact gaacgagcac atttaccttc ttacttgata aagtttactt
    16741 tgtctggcaa aggttcgctt acatataatg ataatcagca acagctaaaa gctggagact
    16801 tattttttat tgactgccaa gaatatcagc gttatcaaac gatcagcgaa gaaccatggg
    16861 aaatggattg gatccatttg aatggtcaga acgtccaatc attttatcag gagttcacaa
    16921 aagacggcca taacaccttc cattcaacag gggatccatc agaaaacaag atccaccatt
    16981 tgatcacaga attgatccac atgcaacaag gcacgaatgc ccgtaccgat ttccagtcct
    17041 ctgtagctat ccacgagttg ctgaatgaac tgattttgca aaagtatcag ctagatttcg
    17101 aagaagagga tattcccgcc tacgtttaca aactgaagca atacttagac gaacatttca
    17161 aagaaacgat tacacttgat caattagaac aacaattctt attgaataaa tatcagctga
    17221 gcaaagattt ttccaaattt atcggttctc caccaatcga ttatttgatc agcaaaaaac
    17281 tttcttacgc taaagacctt cttcggtata cagaatttac ggttcgaatg atttccgaag
    17341 aaatagggat tgagaatttt gcttacttta gccgcctgtt caaagcaaaa acaggactat
    17401 cgccgagaga ctttcgtaaa ttcagctgat tcatataata tgtacgtcat tttttcaaaa
    17461 tattttgaaa tatatagata aaaataaaat aaccgcagtt tctgcttcta tgtaaacaac
    17521 agcagctact gcggttattt tttagtgatc attctcattg ttcatcttca aaatgttcat
    17581 aatgaaccaa ctgtttctgt gtatcacgtt tcaaaaattc tttaggcgtt atgccgaact
    17641 ctctcttgaa tgctttcaga aaatgcggat aagaagaaaa accactttta ctatatacag
    17701 cactagagct gcggtattct cgcaacaagt gcttggcata gatcagcttt ttcttcatta
    17761 catactgatg aaacgtaaat ccagtgtact ttttaaattc tcgtgtgata tggtatttgc
    17821 tgacaaaaaa ctgcttttcc atttcctcta aagaaagcgg atgagataaa ttttttgaga
    17881 tatattgtaa catttgttcc acacgctcat taggaactac agcattctgt tcttgcgcac
    17941 tctcttcttt ttgtacaact tgattgagaa aaatcaagta ttctaccaga gcttgttcat
    18001 attttatgtc ttcaccgtaa atttttttat caggaggatg gtcgataaat gataattttt
    18061 gcttcaatac ttcctgttct atttgcaata cacgactcct cttctctccc attggttgaa
    18121 agcaagccga tagattagac catggcgtgg aacgactttc tagaaaagaa ggggtgacaa
    18181 agatatagac acgctcgaat acatctgaag attggcggac gatacgatgc aaatcattgg
    18241 aatggatgag cagcacactt cctgctttga tcgtaaattg tcgtccgttc aaataaaaag
    18301 tcgcttctcc ctttaatgta gcatggatct catagaaatc atgatgatga tagatcgttt
    18361 tattttggct gacgacatct ttgacatgat agatttcata ctgatcagaa accatcgtat
    18421 tgacttgttc accgctgatt ttcttttgga gcatgtgccg cacctccttt tgttcactta
    18481 tgcacaattt tattatacca cgttttttgt aatcaaaaag agctgctttt atatactctt
    18541 ataaaaaaga agagacgtgg catcttctag ccccgccccc tccattctaa atattagtta
    18601 accaacgtct tctttacatt attcaagaag acttcttcca taacgaatcc catcatcttt
    18661 tgtttcttca agaaccacat acaggtacgg acgattcttc atgatgattt ctttgatttt
    18721 tgtgtactcg atcacaccgt ctcccaaatt taccggcacg attttttcct gttcgacacg
    18781 aaaatctttc aaatgaaccg cacatatctt ttcaccaaaa cgttcaaaag cttcttctac
    18841 caattggact tgttcttgat aatcactact tgtgatcaaa ttggtcggat ctaaaatgat
    18901 tcctagatag tccgaatcta ctgcttggat cagctgctct acccttgcta aagaatacac
    18961 cggatgattc aaacctggtt ctatccccac catcatttgg tatttttctc cagcttttac
    19021 caagcgacgg ataacggaca cagcttcagc aaatgcttca tctgtgaaat tttcttccgt
    19081 atattggatt tccggcaaaa cacatccagt ttccgaagca accatcgacg caccaaagga
    19141 agaagcatag cgaagatact gctcgaactt tgtcagcaac tcttgtcgta tcgttaaatc
    19201 tggatgaatc atattgatat agcaacttaa aattcctacg gtcacttctt gcttttctaa
    19261 aactcgtttg acataatttc ccatcccaga attgatctca tttgcgccag aaggtatttc
    19321 aggaaacgaa agacctaagg cgagctgcag tgtatgaatc ccttgttctt ttgttttttc
    19381 tgcaagatct tctatcgttt ggacttcgga aagatcatgt cctctaattg taatgttcaa
    19441 cataactatt ctcctaactc agcatattgg gtagccacat gacgatttgc gggaagtaag
    19501 taatcaaaaa caagacgact aagataaccc cataaaaagg aagaagcggt ttcagcattg
    19561 cctctgcttt tacgcctcct acacttgcac cgacatatag tcctgtacct actggcggcg
    19621 tgatggagcc tacacacaga ttcatgattg aaaacaaccc gtaatgtaca ggatcaaccc
    19681 ctacacttgt gacgattggt aaaaatattg gtgtaaaaat caagatagca ggcgccacat
    19741 ccataaacat acccaccagt aataacacaa gattgactaa taacagaata ataaatttat
    19801 tatccgttac gcccataatc aacgaactaa ttgcctgagg aataccggta aacgccatgg
    19861 cgaaagacat catggaagaa gtagccaata agaacatgat cgtccctgac attgctactg
    19921 attgaaacaa catattaggt atatctttta gttttaccgt tttatagtaa aacatagcaa
    19981 tcaacaggga gtaaatgaca gctatcgctg aagcttctac tgctgtaaat atccccgtca
    20041 agataccacc gataatgatg acaatcaata gaaggctagg aatcgcctct tttattattt
    20101 ttccagcatg agccatctgt cctttttcga caacagggta tttattcttt ttagcaacga
    20161 tgaatgctac tagcatgatt cctagcgccc acaaagcgcc tacgagataa cctcccataa
    20221 acaaagcaga gatcgaagca ccaccagcaa caagtgaata catgataaaa gcagtacttg
    20281 gaggaatgac catacctgtc ggagctgacg cgatattgac cgctgtcgca aacttccggt
    20341 catatccttc ttccacttgc tgagggatca acactccgcc aatcgcggta gaagcggcaa
    20401 tggccgagct agagatggaa ccaaataaag cattccctaa cacattcgta tgagccaaag
    20461 cccccggcac gcgcccgacg aacaacatcg caaaatccac tagtttctta gctatccctc
    20521 cattattcat gataatgccc gagagaacga aaaacggaat agcgatcagc gaaaaactat
    20581 tgatacttcc caccattttt tgagctgaac taaaagcaga aacatcaaac ggtataacta
    20641 acaataaagt catcatcgat gagaatgcaa tacttatagc aatcggcatc cctaatacaa
    20701 gcaacacaac aaatacaaaa aataacacta atccggcttc tattgccatt ttattcctcc
    20761 atttttatat tttttcttga attgctggct tgttgcttaa tgtatcgatt agattgatca
    20821 ggctatagat aatgatgagt acccccgata caggtactga cagataaaca tatcccatag
    20881 gaatacttaa agaaggcgag atctgcccca ttgtcaatgt gacagcattc catccgccat
    20941 acaccatgat catcgcagca aataccagaa ataaactttg aacaacaact tctaaaattt
    21001 tacttttttt gccagttaat ttttcactta aaaccgttac ggctaaatgt gctttttgtc
    21061 ccacaacata cgcggaagac aacatggcaa accagacaag accgaatcga acaagctctt
    21121 ccgtgaccgt atttggattt cctaaaaccg ttctggaaaa tacttgccat aaaacaacag
    21181 cgaccatccc aacaagcaaa acagctccca ggatctctaa taccttgttt aaaatcattt
    21241 tcatcacagc tacgctcctt gctcttggat cttttgataa aggtctttgt aggtaggatc
    21301 gtttttgaat atatcatgaa gtggggcaac tgcctctcga aacggtgtat tatctacatc
    21361 attgaattgg actccatgtt cttcttgtgc taaagctttt tcttcttcaa ttgcttttgc
    21421 aaaagcttca atttcaaaaa ccgttgattc tttcgctgct tcttcaatgg ctttttcctg
    21481 ctcatcagtt agctgttctt tgatggcatc attcatgatg atgatatctg gcacacgtgt
    21541 atgctcatca taggaatagt atttagccac accaccatgt ccagctgtat acaagacaaa
    21601 ttcattgttt tctgatccgt tgatcaaatt ggattgaaga gacgtgtaca cttcatcact
    21661 tcccataggt acgggcgaac cgcctaaaag ctctaccatt ttgatagcgg tttcgctttg
    21721 catcacacgg atcttctttc ccttcaaatc ttccggcgta tggatcggac cgtctaccat
    21781 ataaaagctg cgctgaccag aatcataata ggtcaatccg gtaaatccta aatttttggt
    21841 cgattggtag attggctcca ttatttcttc attatccatc accttaaaga aatgttcttc
    21901 atcattgaat agataaggaa ctgaaaaaat cgaataatct ttagagaaac tttccaacgc
    21961 tgaggcactt acttttgtga aatctactgc tcctgactgt gtcaattcga tcagttcacg
    22021 ttctccaccc agttgtccat ctgggaaata ctggatctgt acggaaccat ctgttttttc
    22081 ttttactaaa cgcccaaatt cattcattgc atcaattact ggctggctgt tgcttgcata
    22141 agcaaagcgc aaggtaacta tctcatttac atctgcatct gcgacagttg ccacactaga
    22201 attatttccg cagccgctta gacctagcag acctaggcta agcgaacttg ctgcaaacag
    22261 cagtgatgtt tttttcatat gggtttcctt tcttttaaca ataagagacg agcaattctg
    22321 tcaaacaaag caccgttaac gactgtccat aaggcattgc tgtgattccg atattccgat
    22381 aaaaatctaa actgtccccc attcctgtcc cgattgaaac gttttgaact tctccttttt
    22441 catcgatttg ttcaagcaat ccttggatag cacgataagc gacttcttta tattcttgtg
    22501 gtaaataacg tttatggacc gctttcaaaa taccgtaagc aaatcctgca gttgcagaag
    22561 attctacgta agaagaagga tcatccaaca acgtatgcca taaaccgctt tcagactgat
    22621 aagtttttaa tgcacgcact tgtgcttcaa gtgtttcgat caataatttg cgcaatgcat
    22681 cttctttcga taattctaag atttcaatga tctctggaat agcaatcgtc aaccagcagt
    22741 ttccacgagc ccaaaatgct tcggcatagt tatgatttcc ttcaaacgtc cagccgtgat
    22801 accacaatcc tgttcgttta tccatcaagt atttgatatg gatcataaac tggtaacgag
    22861 cttcttctaa atattctggg cgattcaaca gtttcccgat ttttgccaaa ggaagcactg
    22921 tcatcatcaa tgtatcgtcc cacaactgat tcttattttc cggtccatat gtggcatgct
    22981 gtaacccgtc ttcatttgtc cgaggcatgt cattcatgac ccattctgcc cattgttcta
    23041 aataaggcaa atagcgtgaa tctttcgtgt cttcatacaa gtaagccata gtcaatagcg
    23101 gtgccattgt attgacgttt ttgggcggag cgccttcttc catacgatcc tcaaaccatt
    23161 cattgaccac ttgataagcg cgaggatttt ttgtcatctg gtaattttta taaataccat
    23221 atagaccgac accttgtggc caattccaca ctgtccagct tttgtcatct actttcagtc
    23281 catcaaagtc caacaaaaat tcaccattat cgtctttgat cgttgtcagg ttttcaacga
    23341 gcaggtcaat tttttctttc actaattctt taggtacaaa aatctcttct ttaataatca
    23401 tctttacgcc acttttttaa acgctttcat tttatatcct taatatagca gtaataccgt
    23461 ccactataaa tatcgctttt tgaacaaaaa ctgtctaaaa ttgacctaaa tgttaaataa
    23521 caaaagtaac tttcagttac ttggaaatta aaaaaagaac ttggagaaac aacgtttt
//
LOCUS       DARPZF010000039        23365 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.040, whole genome shotgun sequence.
ACCESSION   DARPZF010000039 DARPZF010000000
VERSION     DARPZF010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23365
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.040"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(110..181)
                     /locus_tag="SLE65_001926"
     tRNA            complement(110..181)
                     /locus_tag="SLE65_001926"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(146..148),aa:Arg,seq:ccg)
     gene            241..1575
                     /gene="rpoN"
                     /locus_tag="SLE65_001927"
     CDS             241..1575
                     /gene="rpoN"
                     /locus_tag="SLE65_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HEI8449219.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            1724..2815
                     /locus_tag="SLE65_001928"
     CDS             1724..2815
                     /locus_tag="SLE65_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HEI8449220.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            2856..3857
                     /gene="gap"
                     /locus_tag="SLE65_001929"
     CDS             2856..3857
                     /gene="gap"
                     /locus_tag="SLE65_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEI8449221.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            3967..5157
                     /locus_tag="SLE65_001930"
     CDS             3967..5157
                     /locus_tag="SLE65_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEI8449222.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            5261..6016
                     /locus_tag="SLE65_001931"
     CDS             5261..6016
                     /locus_tag="SLE65_001931"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEI8449223.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            6132..7430
                     /gene="eno"
                     /locus_tag="SLE65_001932"
     CDS             6132..7430
                     /gene="eno"
                     /locus_tag="SLE65_001932"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEI8449224.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            7829..8968
                     /locus_tag="SLE65_001933"
     CDS             7829..8968
                     /locus_tag="SLE65_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HEI8449225.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(9035..9610)
                     /locus_tag="SLE65_001934"
     CDS             complement(9035..9610)
                     /locus_tag="SLE65_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEI8449226.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(9615..10589)
                     /locus_tag="SLE65_001935"
     CDS             complement(9615..10589)
                     /locus_tag="SLE65_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HEI8449227.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(10613..10657)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            10872..11840
                     /locus_tag="SLE65_001936"
     CDS             10872..11840
                     /locus_tag="SLE65_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEI8449228.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            11937..12230
                     /locus_tag="SLE65_001937"
     CDS             11937..12230
                     /locus_tag="SLE65_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEI8449229.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            12348..12584
                     /gene="secG"
                     /locus_tag="SLE65_001938"
     CDS             12348..12584
                     /gene="secG"
                     /locus_tag="SLE65_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEI8449230.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            12687..13442
                     /locus_tag="SLE65_001939"
     CDS             12687..13442
                     /locus_tag="SLE65_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEI8449231.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            13445..15802
                     /gene="rnr"
                     /locus_tag="SLE65_001940"
     CDS             13445..15802
                     /gene="rnr"
                     /locus_tag="SLE65_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEI8449232.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            15824..16288
                     /gene="smpB"
                     /locus_tag="SLE65_001941"
     CDS             15824..16288
                     /gene="smpB"
                     /locus_tag="SLE65_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEI8449233.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            16590..17309
                     /gene="atpB"
                     /locus_tag="SLE65_001942"
     CDS             16590..17309
                     /gene="atpB"
                     /locus_tag="SLE65_001942"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEI8449234.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMVISLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            17362..17577
                     /gene="atpE"
                     /locus_tag="SLE65_001943"
     CDS             17362..17577
                     /gene="atpE"
                     /locus_tag="SLE65_001943"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HEI8449235.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVVALILVFGV"
     gene            17668..18192
                     /gene="atpF"
                     /locus_tag="SLE65_001944"
     CDS             17668..18192
                     /gene="atpF"
                     /locus_tag="SLE65_001944"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEI8449236.1"
                     /translation="MLNQLAIAEVGNAMLGNVIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            18179..18721
                     /locus_tag="SLE65_001945"
     CDS             18179..18721
                     /locus_tag="SLE65_001945"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEI8449237.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYAYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMNYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLENMRNQLNR"
     gene            18744..20300
                     /locus_tag="SLE65_001946"
     CDS             18744..20300
                     /locus_tag="SLE65_001946"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEI8449238.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            20314..21216
                     /locus_tag="SLE65_001947"
     CDS             20314..21216
                     /locus_tag="SLE65_001947"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEI8449239.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            21239..22645
                     /gene="atpD"
                     /locus_tag="SLE65_001948"
     CDS             21239..22645
                     /gene="atpD"
                     /locus_tag="SLE65_001948"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEI8449240.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            22659..23081
                     /locus_tag="SLE65_001949"
     CDS             22659..23081
                     /locus_tag="SLE65_001949"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEI8449241.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         7865 a         4237 c         4990 g         6273 t
ORIGIN      
        1 atctatacag atacaacaaa aaactgtcca ccaattctct ttggcggaca gttttcactt
       61 aaaaataaag aagcaactat tcgtaaatta tgctaaaata gcagtagaac gcgtcctgag
      121 ggaatcgaac ccccgtctca agaaccggaa tcttacgtga tatccactac actaaggacg
      181 caagcactgg gataattgta actaaacaga taaaaaatta caaggggatt ggacaaaaaa
      241 atgaaatttg agcaaaattt ttcacaaaaa cagcagcaga cacagaaact agccatgacg
      301 caacagttgc aacagtccat ccaagtttta caatataaca gtgaggagct gttggcattc
      361 gttgagaatc aagcaatgga aaatccattg gtggaagttg ttgagccgga atggcagcca
      421 gattacataa aagcttcttc atcttcttat gaaggagaag agacaaatta cctaaatcag
      481 attcctgata caaaagggtc tttatttgat tcattgatcg aacaagtcca tttgaattac
      541 cgagatactt ttttgaggaa aatcgttctt tatcttgtag aatacatcga tttgaacgga
      601 tttttgacga ttagtttaga agaagccgga aaagagattg gagctacgcc tatccaaatg
      661 ctcgatgcgt tgactctgat tcagcaatta gaaccagctg gagtaggtgc acgtagtttg
      721 caagaatgtc tcatgcttca aacagaacga gatgattatg cgccggaatt agcttatatc
      781 gtgttggaag aatgttttga ggaactggtg gagcgaaaat ggaaagaaat cgcacaacgt
      841 ttttctgttg atctacatgc tgttcagcag atattcgact atttacaaac gttgagtcca
      901 agccctggcc ggattttcga ccgtagcagc gaattgtaca ttattcctga tgtccgggta
      961 ttagtggacg acgataaaaa tgtacaagtt atctcaaacc gaaaaaatca gccaaatata
     1021 cgctttcaag agagttactt caaacaaatg tcacaacaag cagataaaga aactgaaaat
     1081 tatttaaaag aacggaaaca ggaattcgaa tggttgaaga aaacgatcct ccaacgtggg
     1141 gatacaattt tgcgggttgc tcaagtcatt gtttcccggc aaaaagcttt ctttatcgac
     1201 aaggaacgtc caatcaagcc tcttacgtta aaggaagttg caactgagat agatgtgcat
     1261 gaatccacgg tcagtcgtgc agtcaacggg aaatatttgg aaacagattt cggtgtattt
     1321 gaattaaaaa aatttttcac tacacgaatt cctacgaata gtacagaaca gacagaagac
     1381 ctttcagcag atacagcgaa gaaaaagctg caggaattag tcgatcaaga agacaaaaac
     1441 aagccgttgt cggaccagaa attggttgaa ttgctgaaaa aagatgagat agcgatctca
     1501 agacgaacag tagcaaaata tcgtgattta ttaggaatcc cgagttcatc aaaaagaaaa
     1561 cgttatgata actaatcagt caaaagacta gaaaaagtat ttcacttttt ctagtctttt
     1621 tagttgaaaa acgagagcaa aactgttaga cttacagtcg tgaggttgag atttcccttt
     1681 attgatgtga aattcgaata gttaatttct ttttttatcg tatatgggtc gttttaagtc
     1741 tacattggac gtaaagtgtc caactaagga gatcgctatg ctggatgaaa taaaaatgat
     1801 tgaatctgtt gcaccagata ttatcgaagt gttgcaagaa cgctataaaa ttttacgaaa
     1861 tatctattgg atgcagccga ttgggcgtcg aagtttatcg gaaagtatgg ggatcacaga
     1921 acgagtctta cgaacagaaa cagacctttt gaaaaatctg aatttgatcg acacctcaaa
     1981 aagcggtatg acgctgacaa ctaagggcga agaagtttat caaagccttg aaaacttcat
     2041 ggatcagctt ttaggtacgc atcaaaccga acaacagttg gcagaatatt ttggtaacca
     2101 acgctgtatc gttgtttcag gaaacagcga agagcagacc aaagtggctg atgcattcgg
     2161 cgaagcgctg agcgaagcct tagaccgact acttccagaa ggcgagaata tcatcgctgt
     2221 gatgggagga actactatgg ctgtggtagc cgaacaattg tctaatctgg aaaataagaa
     2281 acggcataac ctgtttgtcc ctgcaagagg cgggattggt gaagcgataa ctgtacaggc
     2341 aaattctgtc agtgcaagaa tggctgctaa agcaaacggt aaccaccgcg cactttatgt
     2401 tccggaacaa ttaagtctgg caacttacaa ttctttactc aatgagccat ctatccaaga
     2461 agtcttaaac ttgattagtg aagcgaattg tgttattcat agtattgggc gtgcattaca
     2521 catggcagca cgtcgtaaga tgactgaaaa agaattagtc atgctgaaac aagcaaatgc
     2581 tgttgcggaa tcttttggct actttttcaa tgaaaaaggt gaagtcgttt ataaggtccc
     2641 tagaatcggc atagaattgc aagatttgga aaaagtcccg atcatcatgg caatcgcggg
     2701 cggaaaatca aaagctaaag caattcgagc ttatatgaaa aatgcaccaa aacaaacgtg
     2761 gctcatcact gatgaagctg ctgcaaatga gattttaaaa ggggtaaccc tttaaaataa
     2821 atattttttt gattttcata aggaggaaat cttaaatgac agttaaagta ggtattaatg
     2881 gttttggacg tattggacgt ctagcattcc gtcgtatcca agatgtagat ggaatcgaag
     2941 tagtagcaat caacgacttg acagatgcta aaatgttggc acacttgtta aaatacgaca
     3001 caactcaagg acgtttcaac ggaacagttg aagttcatga aggttcattc aacgtaaacg
     3061 gaaaagaagt taaagtatta gctaaccgca acccagaaga attaccatgg ggcgaactag
     3121 gcgtagatat cgttctagaa tgtactggtt tcttcacttc taaatcagca gctgaaaaac
     3181 atttaacagc tggtgctaaa cgcgttgtta tctctgctcc tggcggaaac gatgttccaa
     3241 caatcgttta taacacaaac cacgaaacat taactggtaa agaaacagtt atctcaggtg
     3301 cttcatgtac tactaactgt ttagctccta tggctaaaac attgaacgac aaatttggtg
     3361 ttgttgaagg attaatgaca actatccacg cttacacagg tgaccaaatg actctagacg
     3421 gacctcatcc taaaggtgac ttccgccgtg cacgcgctgc tgctgcaaac atcgttccta
     3481 actcaacagg tgctgctaaa gctatcggtt tagtaattcc cgaattgaac ggtaaattag
     3541 acggagctgc tcaacgtgtt cctgtaccaa caggttcatt aacagaatta gtaacagttc
     3601 ttgaaaaaga agtaactgtt gacgaaatca atgcagcaat gaaagaagct tcaaacgaat
     3661 cttacggata caacacagac gaaatcgttt cctcagatat cgttggtatg acttacggtt
     3721 cattatttga tgctacacaa actaaagtaa tgacagttgg cgacaaacaa ttagttaaaa
     3781 ctgttgcttg gtacgacaac gaaatgtcat acactgcaca attagtacgt actttagaat
     3841 acttcgctaa cttataagat agacaaacgt acaagtgtaa attatagaca tgtacattta
     3901 aaagcgggga agcaatcgcg cttcttccgc tttttttgat aataagttta ttcaggagga
     3961 aataaaatgg ctaagaaaac agtgaaagat atcgatttaa aagacaaaaa agttcttgtc
     4021 cgtgttgact tcaacgttcc tttgaaagac ggcgtgatca ctgacgacac tcgtatcaaa
     4081 gcagcattgc caacaatcaa ctacgttcta gaacaaggcg gaaaagcaat ccttttctct
     4141 caccttggac gtgtaaaaac agaagaagat aaagaaggaa aatctttagc tccagttgca
     4201 aaacgtctag gcgaattatt aggtaaagaa gtaacattcg tacctgaaac tcgcggagaa
     4261 caattagaag aagcaatccg caacatgaat gacggcgacg ttgtcgtatt cgaaaataca
     4321 cgttttgaag atattgacgg taaaaaagaa agcaaaaatg atacagaact aggtaaatac
     4381 tgggcttcat taggcgatgt atttgttaac gatgctttcg gtacagctca ccgtgcacat
     4441 gcttctaacg taggtatcgc ttcaactggt atcccaacag ttgctggatt cttgatggaa
     4501 aaagaaatca agttcatcgg tgaagcagta gaagaaccaa aacgcccaat gattgcaatc
     4561 cttggtggcg caaaagtttc tgataaaatc ggcgtaatcg aaaacttgat tcctaaagca
     4621 gataaaatct taatcggtgg cggaatgact tacacattct acgaagcaaa aggaatcaag
     4681 atcggtaact ctctagtaga agctgataaa gtagaactag caaaagaatt aatcgaaaaa
     4741 gcaggcgaca aacttgtctt gccaatcgac aatgtctgtg caccagaatt ttcaaatgat
     4801 gttgaaacac aagtaatcga aggagacatt cctgatggtt tgatggcttt agacatcggc
     4861 ccagcatcag taaaattatt tgctgataca ttacaaggtg caaaaacagt tgtttggaac
     4921 ggacctatgg gtgtatttga aatgagtaac tttgctaaag gtacaatcgg tgtttgtgaa
     4981 gcaatcgcta acttagaagg cgcaacaaca atcatcggtg gcggagactc agctgcagca
     5041 gcagaacaat taggattcgc tgacaaattc acacacatct caacaggtgg tggcgcaagc
     5101 ttggaattgc ttgaaggtaa agaattacca ggactagcag caatcaacga taaataaacg
     5161 accaagtttg ctcaattctg acgagtaatc gatcaaaagg tgaagggagt tttcatgact
     5221 ccctagccat ttttcaataa attaaggagt gtgttcctca atgcgtaaac ctattatcgc
     5281 aggtaactgg aaaatgaaca aaactgcatc agaagcaaaa gaatttgctg aagcagtaaa
     5341 aaacaaaatc ccttcaaatg acaaagttga ttcagtcatc ggatctcctg cattattctt
     5401 acaagaatta atgacatcag ctgaaggtac agaactaaaa atctcagcac aaaactgcta
     5461 ctgggaaaac tcaggtgcgt tcactggtga aacttcacca gcagctcttg ctgatctagg
     5521 tgttcattat gtgatcatcg gacattcaga acgtcgtgaa tatttccatg aaacagacga
     5581 agacatcaat aaaaaagcaa aagctatctt tgcaaatggt atgacaccaa tcctatgctg
     5641 cggcgaatct ttagaaacct atgaagcagg caaaactgct gaatggatcg aaggacaaat
     5701 tacagctggt ttagctgatc tttcagctga acaagtgtca aacatggtta ttgcttatga
     5761 accaatctgg gcaatcggta ctggtaaatc agctgacgca caaatcgctg acgaaatttg
     5821 tggagttgta cgtcaaacag ttgaaaaact ttatggaaaa gaagtatcag aagcagttcg
     5881 tatccaatac ggcggttctg taaaaccaga aaatattgct gaatacatgg caaaagaaaa
     5941 tgttgacggt gctttagtcg gtggcgcaag cttgcaagca gattcattct tgtcattgtt
     6001 agacgctgta aaataattgt tgaaaatttg tgaaaaatgc aagaaatgtt tgcactaatg
     6061 agcaaaatta actaaaatcg tatatgaggg aaatccctta ggaaaaaaca aactcaaagg
     6121 agagacaaaa catgtcaatt attactgatg tttacgctcg cgagatctta gactcacgtg
     6181 gtaacccaac aatcgaagta gaagtataca cagaaagcgg agcttttggc cgcggaatgg
     6241 ttccttcagg tgcttcaact ggtgaatacg aagcagttga attacgtgac ggagacaaag
     6301 ctcgttatgg cggtaaaggt gtaactaaag ctgtcgacaa cgtaaacaac atcattgctg
     6361 aagcaatcat tggctacgat gttcgtgacc aaatggctat cgacaaagct atgatcgctt
     6421 tagacggaac tcctaacaaa ggtaaattag gtgcgaacgc tattttaggt gtttctatcg
     6481 ctgttgcacg tgcagctgct gactacctag aagtaccttt ataccactac ctaggcggat
     6541 tcaacacaaa agtattgcca acaccaatga tgaacatcat caacggcgga tcacatgctg
     6601 ataactcaat cgacttccaa gaattcatga tcatgcctgt tggcgctcca acattcaaag
     6661 aagctctacg tatgggtgct gaagtattcc acgcattagc ttcaatcttg aaagctcgcg
     6721 gattagcaac ttctgttggt gacgaaggtg gatttgctcc aaaccttggt tcaaacgaag
     6781 aaggttttga agtaatcatc gaagcaatcg aaaaagctgg ctatgtacct ggtaaagacg
     6841 ttgttcttgc tatggatgct gcttcttcag aattctacga caaagaaaaa ggtgtttacg
     6901 tactagctga ctcaggcgaa ggcgaaaaaa caactgacga aatgatcaaa ttctacgaag
     6961 aattagtttc taaatatcca atcatctcaa tcgaagatgg attagacgaa aacgactggg
     7021 acggattcaa gaaattaact gacgtattag gcgacaaagt tcaattagtt ggtgacgact
     7081 tgttcgtaac aaacactcaa aaattatctg aaggtatcga aaaaggaatt gctaactcaa
     7141 tccttatcaa agtgaaccaa atcggtacat taacagaaac tttcgaagct atcgaaatgg
     7201 ctaaagaagc tggctacaca gcagttgtat ctcaccgttc tggtgaaaca gaagattcaa
     7261 caatctctga tatcgctgtt gcaacaaacg ctggccaaat caaaactggt tctctatcac
     7321 gtactgaccg tattgctaaa tacaaccaat tactacgtat cgaagaccaa cttggtgaag
     7381 ttgcagaata caaaggtttg aaatctttct acaacttaaa aaacaaataa ttcttttcta
     7441 atgaagatac atgatcgact attgaaagat agtcgagtat gatcacttag ttaagtaatc
     7501 gaactctcta cttgctgaaa tatcagcagg tagagagttt ttttgcaact agcttctgta
     7561 tatgatgttt acaaagaatg gtacaagaaa agatcatcct tgaaaaagga aagctaacaa
     7621 taactagcat catataagag cttttaagga tagaacagta gaataggaat ctatgagcaa
     7681 gtcctctcgt ataaataaaa taggagggaa gtagcagcat atttttcata aagtggctct
     7741 ctttcttcat ttttactttg gttgctccta tttgaaaatt cgagcacact caaatacaat
     7801 aaaaagaaat ggcaagggag aggattagat gaaaaaagaa gaaaaaatcg cgattttaca
     7861 agagatcatc cgaattaaat cagtgaatgg aaacgaaggt gaagtagcag cctatttgaa
     7921 taagcttttg gcaaaacatg acataacagg agagattgtt tcttacagag atggtagaga
     7981 taatttgatt gctcgttacc aaaagggcca atcaggaaaa gtgttaggcc tatctgggca
     8041 tatggatgtc gtggcggctg gtgatgaatc gtcttggacc tatgcaccct ttgcagcaga
     8101 aatccatggg aaccgtttgt acggacgtgg tgctacagat atgaagagtg gcttggcagc
     8161 aatggtgatt gccatgatcg aactgaaaga gtcaggaaaa ccatttaacg gaacagtcaa
     8221 attattagcc actgtcggag aagaagtggg tgaactaggt ggggaacagc tcacgaaagc
     8281 aggctatgta gatgacttag atgccttgat catcggagag ccaaccaatt acagtttgat
     8341 gtatacgcac atgggatcaa tcaactatac agtcacctcg cacggaaaag aagcgcatag
     8401 ctctatgcca gaccaaggtt ataatgcaat caatcaccta aatgaattca ttacgaaagc
     8461 aaatgctgaa atgaatcacc tcgctgaaac aatcgagaat cctgtcctag gaaaaacaat
     8521 ccataatgtt acattgatca gtggcgggaa tcaagtcaac agcatcccaa gccatgcgca
     8581 gctccaaggg aacattcgat cgattccaga atacccaaat gataaaatca ttgcattgct
     8641 gcaatcaatc gtcaatgaat tgaatcaaga gacagactat catttggaat tgatgatcga
     8701 ttacaacaaa atacctgtca aagctgatcc agattctcct ttgattcatt gcattcagca
     8761 acaattcagc cagccattac ctttagttgg agcggcagca acaacggatg cagccgaatt
     8821 tacgaaagct aaccattcct tcgactttgt cgtctttggg cctggtgtcg ttactttgcc
     8881 tcatcaagta gatgagtatg ttgaaatcga taattatttg gatatgatcg aaaaatatca
     8941 aggaattatt ttatcctact tagcgtaaga tttttttaat aaatgaaaaa acagagccag
     9001 attagcatta ttttgctaat ccagctctgt ttattcagcc tatttttctt tttgaatata
     9061 tcaagcgttg tggcaacata gtgatgacta atgaaacaac gacgatagac aacaaacgat
     9121 caaggtagtc tgtacctgcc tgtaccaaga tcacacttgt tgtctgactt aaacctaacc
     9181 catgtaatag ctgaacgatc atactggatc ctgaggaggt gatcccgcca aataactgaa
     9241 cggtaatgat cgaagaaacg atcgttccag gtaccgacaa aatcaaagcg agtaataaca
     9301 gtttcaagct gtttttatct ttgccgagat atcttggcaa aatcaatcca gcaagcaagc
     9361 ctgtgagaat ttggattggc gaataataca gagaaaaaat atctgtagtc actccactta
     9421 aaataccgct ggacaatcct gtcagcattc caggtacagg cccaagcaat gcaccagcaa
     9481 aaatcgttcc gatagaatcg agatagattg gcaaacgaag ccataaagca atcgttcctc
     9541 caatataatt gatcccaata cacaaagcca tcactgtaag tacgcgagtt gccattttgt
     9601 ttttattcat tttgttagcc catctttaac ctttccaaat ctttcataat cgtttcttct
     9661 tgtgcattta aaagaacggt taaaaacttt cggaaaaaaa gacgagtatc tacttttgtc
     9721 ataattttac tgttagcagg tttctgccaa aattcataac gatcaaccaa tgtttgtcca
     9781 cgacttattc cttgagtttc cacagcagtg aagcttttga aaccttcaca gatggcctcc
     9841 tcgataaaat aagcaacagc taacggatca ttgatgacac atcctaaaat tctttcttgt
     9901 ttccagtgga agtcaaaata aaaacgagtg atcgctttta gatactctcc ctcttcagga
     9961 ttcatttgac agcagtattc gaggatagtc ggtgtcaaga cgatttctct tgtcacatct
    10021 aacccaacca tttctatcgt ttgtttgaga ttctcgaata cataagaagc tgcttcagga
    10081 tcacaccagt aattgtattc agcaactggc gaacagttac catggctttt gtaagttcca
    10141 cccatcgaga caaaacgttc catatgtttc ccaatatttg ggttgacttt caaagcagaa
    10201 gcgatattgg tcaaaggacc caaagcaatg actgatgtat ttgtcttttc tttgaaataa
    10261 tcagccaaaa aatcaacggc atggagaggt tctgcctgtt ttctcaagat catcgggaaa
    10321 tttgtttccc ctaaaccatc cataccatga gtgtcttgtg cactgatgaa aggttgcttc
    10381 aaaggttttt ccattccttg ataaacagga atgtctaaac gatcacagcg ttccaggcat
    10441 ttcagcacat tctgcgtacc tatatctgca gggacattcc cacaaactac ggtaatagca
    10501 actacttcga tatcagggga tttgacagct aatgataaag ctaaagtgtc gtcgatccct
    10561 ggatcgcaat caataattac ttttcgcatt atttccaatc tcctttcttt agagatactt
    10621 agttttttat tctgggaagt ttccgaacca gtccaagacg agcgtcttga ttataatgca
    10681 cgaaattagt atactggctt ttattgcgaa tgtaaatgct ctcttacaag taaatctatt
    10741 gaggagaact ttaagtaaat gatacaatga aaaagaaatg gaatttacgt gtgccgaaaa
    10801 taaagaatcc tatggatcgg tacattggat aatagataga ttatagtttg gcagaaagcg
    10861 gcgggtgtac aatggttatt ttttatttca ttcttattct gataattata gggatcagtt
    10921 accattttct ttcttatttt tatgcaaaga aattagtaag agcgggagta cagagaggat
    10981 atgactggta tgaagacact ggtcatcgtt tgatggaccc tgctgcagtc acgtcagtag
    11041 aaaaaaaacg acaaaaatta gaagaagagt gtgaaagctt ttgggagcag ggaacaccca
    11101 aaacaatcaa aagttatgac gggttgaaac tagctggtca gatgttcatc catccaaata
    11161 agcagaataa atgggtcatt tgcgtacatg attaccgaag cacagggaaa agagacatgt
    11221 ctcatatagg taaaagatat gcagagaaag gattcaacgt tcttgtacct gatttacgtg
    11281 cgcacggaga aagtgaagga gaaatcatcg gaatgggatg gctagatcgg ctagatttaa
    11341 ttgcctggat ccaactcatc ttagatgaac agccgaatgc gtccattatt ttacacggcg
    11401 gatcaatggg agcttctacg atcatgatgg caagtggtga aaaacttcca tcagcggtca
    11461 aaggatttat tttagacagc ggatatgttt ctgtttatgc agaattccga tatatgttaa
    11521 gtaaaatcac tgtctttcct aaaaaaatgg tcatgagata tgcgaatcat tatgcccaga
    11581 aatacgccgg ttactcctta aagcaagcat cagctacgag acagcttggc agcaatcatc
    11641 tgcctttatt agtcatccat ggtgaaagag atcattttgt ccctacagaa gcagcgtaca
    11701 cgattcaaaa tgctacggca ggggataaag cactgctgct tgttccggaa gcagaacact
    11761 tggaagcatc gatgaaagat ccgaaaacct attggacagt gattttttca tttattgaac
    11821 aaagaataac gatgaattaa ttttctcttc ttttttgtaa gtaattcgag gataaataat
    11881 tgtttataga tcaggagact gctaaaataa ggtaggaata aaaaaatatc agttatttga
    11941 ggagtgcggc atatggaaat caaagaagaa aaaatcgtct tgctttattc aatgatgaac
    12001 aacaagagat cggagaaatg acatggtcag atgcgggccc agacatcatg atcattgacc
    12061 atacatttgt agatccagca tatcgtggtc aaaagttagc tgaaaagcta gtgtatactg
    12121 gagtagaatt agcaagacga gacgggaaaa agatcattcc tttatgccct tatgcaaaaa
    12181 aagagtttga aaagaaacca gaatatcaag acgtcttacg tcagtcataa gaataacagc
    12241 tgaaagtttt gaactttcag ctgttattcc atttatatag agttgtcacg gacttttatc
    12301 tatgataaag ttaaagagac gatatctttt gggaaggagg ctgcgatatg tataatttaa
    12361 ttttgggaat cgtgatcgtt ttatcgattg ttatggtcat tgcgattatg atgcagccaa
    12421 gcaagcaaaa tagtgcagcg agtgcattta ccggcggtgc ggatcaacta ttcggcaaac
    12481 aaaaagctcg cggctttgaa gctgtcatgc agcgatcaac tgcagttatg ggagctatct
    12541 ggatgatctt attatttgtc ctagcatatt tatcttcgaa gtagttgaat aagcctctcg
    12601 caaaacggcg ggcggctttt tttattgcaa agagaacgct taagaagaag ttatgaaaga
    12661 aactatggta aaatgaggcg aaagaggtga gacgagtgag acaattacca aaaccccttt
    12721 atgcaaaaca tggaaagcga gcggttttgc tgcttcacgc ttactcagga agtccaaacg
    12781 atgttcgaat gctcgcacga tttttggaaa aagcagatta tacagtttat gcgccgcttt
    12841 ttaaaggaca cggaacaatg gagccatatg atatcttgca agaaaaagca gaaagctggt
    12901 gggcagacac taaaaaagcc atccattttt tacagtctga gcagttttct gatattgccg
    12961 tattaggatt atcaatgggc ggcatctttg ctgtacgagc actagaagaa gaatcagtga
    13021 ttggcggcgg ttttttctgt tcgcctttgt ctcctgtaaa aacaaacgtg cctgaaaact
    13081 ttgaaaaata cgtacgtcaa gtgctgaaga cagcaggtaa atcagagaaa gaaatcaatg
    13141 aaaaagcagt tgcttaccgc tcgttagctg aacaacaatt aatggatata caagatcagg
    13201 cagcaatcgt agaaagtagg ttgtcagata tccaacagcc gatattttta gctcaagctg
    13261 ggaaagatga aatgatcgac cctaatggcg tatttgaaac tgcacgcaag ttgagccgtc
    13321 agcgagtgac acttcaatgg tatcctgaaa gtggtcatgt gattacagtt ggtacagcaa
    13381 gacgcgaatt agaaaaagac gtcttggaat ttttagaaaa attaccttgg aatgaggaat
    13441 aaatatgaca aaagaaacga taaaagagaa aattctcttt ttcatggaaa gcagtcgcaa
    13501 acgcagtttt tctatggaag aaatcgctga aggtttaggg ttccaaaaaa gcgatgattt
    13561 taaattacta gtacaaacga ttgctcaaat ggaaagagaa cagagtatag ttttcaataa
    13621 aaaaggaaaa gtgaaacttc ctttaaaacc aatcttgatc gaaggaacat ttcgagcaaa
    13681 tgaacgagga tttggatttg taacgattga tcccgaagaa gatgacatct atatcccaaa
    13741 agaagcgact ggttttgcaa tggatggaga caccgtagca atcgatatca tgaagcgagc
    13801 aaatacagat atggatcgcg gagcagaggg gaaagtagtc gagattcgag accgggcgac
    13861 tactcagtta gcaggggaat tcgttgctta ttcagaagaa gaaatacaag aaacagatct
    13921 ttacggcgtt gttatcccga aagatagaaa gctcaaccaa tttaaagtat atgcagcagc
    13981 agagggagtt cgtccagttg acggaagtat tgtgctgatc gaactgaccc attaccctga
    14041 aaaagggtat gcgactagtt tagaagggat aatcaagcaa gtgattggtc ataagaatga
    14101 ccctggcatg gatatcctct caattgtcgt ggctaatggt atccctacga aatttcctga
    14161 tgatgtattg tctgaagcag atgaagttcc agatcaaatc agcgaaaagg atataactgg
    14221 acgtagagat ttaagaaatc agctcattgt tacgattgat ggagaagatg caaaagatct
    14281 agatgatgca gttacggtta aaaaattaga taacggtaat tattttcttg gagtacacat
    14341 tgcagatgtt tcttactatg tgacacaagg cagtcaattg gacagagaag catatgaaag
    14401 agggacaagt gtatatttga ctgatcgagt aattccgatg atcccgcaac gtttatcgaa
    14461 tggtatctgt tcactgaatc cccatgttcc aaggctgacc atgagttgcg aaatggagat
    14521 tgatccaaat ggacaagtag tctctcatga tattttccca agtgtgatcc aaacaacaga
    14581 acggatgacc tacacagctg tcaatcaaat cttagaagat caagacgaag aaacgatgca
    14641 acgctatgct cagctcgtac ctatgttcca agaaatgggt gaattgcacc gaatccttga
    14701 aacgatgcga atcaaacgtg gcgcgatttc ttttgaggat cgcgaagcga aaatccttgt
    14761 tgatgctgaa ggacacccaa atgacatcca gctaagaagc agaggaattg gtgaacgctt
    14821 gatcgaatct ttcatgcttg cggccaatga aacggtagct gaacattata ataaattaaa
    14881 tctgccgttt atttaccgaa tacatgaaca gccaaaagaa gaaaaaatgc agcgcttctt
    14941 tgattttgct tcagctttgg gcattctggt ccgaggaacg aaaggaacga tcacaccaaa
    15001 agatttacag catgtgatcg aaggagtaga agacaaacca gaagctgcag ttatcaatac
    15061 tatgttgcta agaagcatgc aacaagcacg ctattcagaa gacaattttg ggcattatgg
    15121 cttagcggca gattactaca cacactttac atctcctatt cgacgctatc ccgatctaat
    15181 cgtccatcgt ctgatccgtt cttacagtga agataaaagt gaaagcaatc aaagttcgtg
    15241 ggctgcggaa cttcctgaaa ttgcagatca tagttctaag atggaacgtc gtgcagtaga
    15301 aacagaacgt gaagtagatt ccatgaagaa agcagaattc atgatggaca aagtgggaga
    15361 agaattcgat gggatcatca gctctgttgt gaaattcggc ctgtttatcg aactgccgaa
    15421 tacagtagag ggattgatcc atatcaatga attgaaacag gactacttcc attttgttga
    15481 aaatcattta gctcttgtag gtgaaagaac tggtctgact tttaaaatcg gacagaaagt
    15541 gcgagtaaaa gtagtcaaag ctgatccaga tgaacgagca gtagattttg aacttgtttc
    15601 cgcagaagag gttacagcgt tggaacggcc aaaaacacga aatggaaaat caggaaaacg
    15661 cgaaggaaaa caagcaggaa aacgcccaga aagaaatggc aagaagaaca aacgatatag
    15721 cgatagtaag caaacgttcg gtaagaaaaa agggaagaag ccattttaca aaggtgttaa
    15781 aaaaaagaaa aagaaaaaat aaaatgagtt ggaggaaaca gctatgccaa aaggcgaggg
    15841 aaaattaatt gcacaaaaca agaaagctcg ccatgattat tcgatcatcg acacgatgga
    15901 agcagggatg gtcttgcaag gaaccgagat caagtcgata cgaaacagcc ggatcaatct
    15961 aaaagatgga tttattcgcg tccgcaacgg agaagctttc ttgcataatg ttcatatcag
    16021 tccttatgaa caaggaaata tttttaatca tgatccgttg cgcacgagaa agttattatt
    16081 acacaaaaaa caaatcatcc ggcttgaaaa tgaattgaaa aatactggaa tcactgttgt
    16141 tcctttaaaa gtctatattc gtaacggcta tgccaaggta ttgattggtc tggcgaaagg
    16201 gaaaaaatct tatgataaac gggaagattt gaaacgaaaa gatatcgatc gacaaattga
    16261 tcgaacatta aaaaatttct ctagataatt tcattatcct ttttcgcata ttcggtgctt
    16321 ttgcttttac ttaatgataa aatttgttag catttaatct gataaaacat gattatcata
    16381 ggttttttct tagatcagga gcaccgtgta taaagaaaaa ttcgcttcgt ttttgactga
    16441 aataaaaaag tgtctaattt tcatgaaaat gttttgaatt ttctgtttca tggtggtatg
    16501 ataccgtgtg gttagaaacc gattggaaaa aaccagatac gcacatgaat tgattttatg
    16561 tgaatttcgg ggaaaagagg tgaaatggat tggatgaacg ctcgctaacg ttccacattg
    16621 gaccaatttg gtttgatggt acagtttgta taatggtgtt actgacctgt ttgattgttt
    16681 tcttcttagc ttactttttt acaagaaatc ttaagttgaa accaacaggc aaacaaaatg
    16741 cgatagaatg ggtcattgat tttagtcgag gaatcgtaac agataatctg cctagaaaag
    16801 aattgagcaa tttccatttg ttggcattta cattgttttt atttgttttt gttgcaaaca
    16861 acatcggttt agtaacaaaa atcgttttac ctaacgaaac aacactttgg aaaagcccga
    16921 cagcagaccc gtttgttact ttaactttgg catttataat gatcttactt actcacttat
    16981 ttggggtgaa aaagttaggc ttcaaaggat atttcgtaaa ttcgttcttg aaaccatata
    17041 gttttatgtt tccgatgaaa ctgattgaag aatttacaaa cttattaaca cttgctttac
    17101 gtctttatgg gaatatttat gcgggggaag ttttgctaac cttgattgca aaaatggtaa
    17161 taagcttagg ctggttctca ttgccgttag caattccatt agagatggtc tggatcgcat
    17221 tctccttgtt tatcggaagc atccaagcat ttgtcttcgt tactttatct atggtttata
    17281 tgagccataa gattgaagtg gaagaataat attcgtttta aaaacaaact actatttatc
    17341 taatttagga ggaaaacaat tatgaattat atcgcagcag caatcgcaat catgggagca
    17401 gcaatcggag ccggttatgg taacggtcaa gttatctcta aaacaatcga atcaatggct
    17461 cgccaacctg aaatgtctgg tcaattccgt acaacaatgt ttatcggggt agctctagtc
    17521 gaagctgttc ctatcttagg ggtagttgtc gccttgattc tagtttttgg tgtttaattg
    17581 aatcagtatt aaggcagaaa caatttggtt tgttactgct tttttacatg aaaactagaa
    17641 gtacttcaaa gaaaggaagg ctcgcctatg ctgaatcaat tggcaattgc agaagttggc
    17701 aatgcgatgt taggaaatgt catcgttgtc agcggctcat ttttgatact actggctctc
    17761 ttgaagcatt ttgcttgggg accaatcagc gatattttga aaaaacgtga agacaagatc
    17821 gccaatgatt tggattctgc agaacaatct cgcatcaact cagcgaaaat ggaacaagaa
    17881 cgcgaacaac aattgttagc ctctcgttct gatgcagctg atatcatcaa aaatgcgaaa
    17941 gaaagtggag aattaagccg ccaaaatatt ttgaaggatg ctcaagaaga agcagctcgt
    18001 ctaaaaagta aagcccaagc tgatatcact gtagaacgtg attcagcgct gaactctgta
    18061 aaagacgatg ttgcagaact atctcttcaa atcgcggaaa aaatcttgaa caaagaatta
    18121 tctccagaaa tgcacgaatc attaatcaat caatatatcg aaggtctagg ttcttcaaat
    18181 gaaactagat aaatatacag taggaagacg ttacgggaaa gctttatttg aactggcgat
    18241 cgattcaaat caagcagaag aaatctatca agatctcgta agcttacgtc aaatctatga
    18301 acaagtacct ggattaggta atatgttaag tgatgttcgt ctagaacctc atgaaaaacg
    18361 agaaatcatg gacaagcttg ttagtggcta tgatggaatc gttaaaaact ttttagaagt
    18421 tgtttatgcg tataaccgaa tggatgatct tttgttcatg atcgaagaat atgaacgtcg
    18481 atatgatgaa catcaaggtt tgctgttggg aagtgtcaca acagcagttc cactttcaga
    18541 cgaacaacga atacaattag aaaagaatgt tgcaaaaaca atgaactatc aatcagtcga
    18601 attaaaacaa atcgttgatt cttctattat tggtggcgcg attgttgaag ctaaccatcg
    18661 agtaatcgac ggaagcattc gcacgcaatt agaaaatatg cgtaatcaat taaatagata
    18721 gtacaaagag gtaggtgaat cgaatggcca tcaaagcaga agaaattagt gccttgatta
    18781 aagaacaaat tgaaaattat caaaacgtgc tttcagtcga agaaatcggt accgtaactt
    18841 atgtaggtga cgggatcgct cgtgcacatg gtttagaaaa cgcgatgagt ggtgagttgc
    18901 ttgaattttc aaatggctca tacggaatgg cgcaaaactt agaatcaaat gatgtaggta
    18961 tcattatcct tggcgatttc gagtccattc gtgaaggaga taaagtaaaa cgaacaggaa
    19021 agatcatgga agttccagtt ggagaggcct tgatcggacg ggtagttaat ccgctaggtc
    19081 agccaatcga cggactaggt gaaatcgtta ctgacaaagc tcgtccagta gaagcaatgg
    19141 caccaggcgt tatgcaacgt aaatctgtta acgaaccaat gcaaacaggt ctaaaagcaa
    19201 tcgacgctct tgtaccaatc ggacgtggcc aacgtgaatt agttatcggt gaccgtaaaa
    19261 cagggaaaac ttctattgcg atcgatacga tcatcaacca aaaaggtcaa gatatgatct
    19321 gtatctatgt agcaatcgga caaaaagatt ctacagttcg tacacaagtt gaaacattga
    19381 aaaaatatgg cgcaatggat tacacaatcg ttgtgaatgc cggtgcgtct caaccagcgc
    19441 cgttgcttta tatcgcacca tatgctggta ctgcaatggg tgaagagttc atgtacaacg
    19501 gtaaacatgt cttgatcatt tttgatgatc tttcaaaaca agctgttgct tatcgtgaac
    19561 tttccttgct acttcgccgt ccaccaggtc gtgaagctta tccaggggat gttttctact
    19621 tacactcacg cttattggaa cgtgcagcaa aattaagtga tgatttaggt ggcggttcaa
    19681 tgactgcctt accatttgtt gaaacacaag ctggagatat ctctgcttat atcccaacaa
    19741 acgttatttc gatcactgat ggacaaatct tcttagaaag cgacttgttc tacgcaggta
    19801 ctcgtccagc ggttgatgcc ggactatctg tatctcgtgt agggggttct gcgcaaatca
    19861 aagcaatgaa aaaagttgct gggactttac gtctagactt agcaagttac cgtgaattag
    19921 aagcatttac acaattcggt tctgacttgg atgcagcaac acaagcaaaa ctaaatcgtg
    19981 gacgccgtac agtagaaatc ttgaaacaaa aattgcatgc accgctagct gttgaaaaac
    20041 aagtagtgat tttgtatgct ttgacacatg gattcttaga tagtatccct gtagacagta
    20101 ttttagactt cgaacatgaa ttattcgaat atctggatac caatcattca gatatctttg
    20161 aaacaatccg tacaacaaaa gatcttccag aagaagaagc gttgaacagt gcgattcagg
    20221 aatataaaga catgttctta gctacaaaag gaaataattc ctctacagaa gataaattga
    20281 aatccattca aaatgcatag tgaggtgaga tgaatgggtg cttcattaaa tgaaatcaag
    20341 acacgtatcg cttcaacgaa aaaaacgagc caaatcacgc gggcaatgca gatggtgtct
    20401 gcttctaagt tgacaaaatc tgaagcttct tcacagaagt ttcaggttta tgcaacaaaa
    20461 gtaagagaaa tcgttacgca tttgactgct actcagttaa atgatattgc ctcagaaaat
    20521 cctagagggg atatcaatta caacagcatg ctgctcagcc gtcctgttaa gaaaactggt
    20581 tatatcgtca tcactgcaga tggcggttta gtcggtggat ataacagctc gatattgaaa
    20641 caaacgatgt ctattttaga agaagaccac caatcacccg atgattacgt gatgatcgca
    20701 attggcggaa ctggtgcaga cttctttaaa gcacgcggta tcaatctagc atatgagctg
    20761 cgcaatctat ctgatcagcc aagctttgat gaagtccgca aaatcgtaaa tatggcaaca
    20821 actatgtacc aaaacgaagt attcgatgaa ttatacgtat gttataacca tcatatcaat
    20881 tcgctaacta gtcagtttcg tgtagaaaaa atgctgccaa tctcagactt agatccagaa
    20941 gaagcaacta ctttcgaaca agaatatatt tttgaacctt caaaagaaga aatcttgtct
    21001 cagttattgc ctcagtatgc tgaaagtttg atctacggtg cgatcgttga cgccaaaaca
    21061 gcagaacatg ctgctggtat gacagcaatg aaaacagcaa ctgataatgc tgctaatatc
    21121 attgatgagc tgacggtttc ttataaccgt gcaagacaag gggctattac ccaagaaatt
    21181 accgaaattg ttgccggagc ttcggcacta gaatagtatt gagattggag gaaaaaagat
    21241 gagttcaggc aagattgttc aagtaatcgg tcccgttgtc gacgtggaat tttctttaga
    21301 ccaatcctta ccagatatca acaacgcatt agttgtttat aaaaatgacg aaaataaatc
    21361 aaaagttgtt cttgaagcag cgttagaatt aggggacgga gtgatccgga ccattgcgat
    21421 ggaatcaaca gatggtttac aaagaggaat ggaagtcatt gatacaggca aagcaatctc
    21481 tgttcctgta ggtaaagaaa cattaggtcg cgtattcaac gtactaggag atacgatcga
    21541 tttagaaaca cctttcccag aagatgcgga aagaagcgaa attcataaaa aagcaccagc
    21601 ctttgacgaa ttaagtacaa gtacagaaat tttggaaaca gggatcaaag ttatcgattt
    21661 gcttgcccca tatttaaaag gtgggaaagt cggactattc ggtggtgccg gtgttggtaa
    21721 aaccgtactg atccaagaac tgatccataa tatcgcccaa gaacatggtg gtatttctgt
    21781 atttactggt gtaggtgaac gtactcgtga aggtaatgac ttgtattatg aaatgaaaga
    21841 ttcaggagtt atcgaaaaaa cagccatggt gttcggacaa atgaacgaac caccaggtgc
    21901 acgtatgcgt gttgctttga ctggtttgac gattgcggaa tatttccgtg atgtagaagg
    21961 tcaagatgta ctgttgttta tcgacaacat tttccgtttc actcaagctg gatctgaagt
    22021 atcagccttg ttaggacgga tgccttctgc ggttggttat caaccaacat tggcaacaga
    22081 aatgggtcaa ttgcaagaac gtatcacatc tacgaaaaaa ggttcgatca catcgatcca
    22141 agcaatctat gtgccagccg atgactacac tgacccggcg ccggcaacag cattcgccca
    22201 tttggatgcg acaaccaact tggaacgtaa attaacagaa caagggattt atccagcggt
    22261 agatccattg gcttcttctt caagtgcttt agcacctgaa atcgtgggag aagaacatta
    22321 taaagtagca acagaagtcc aacacgtatt gcaacgatat cgtgaattac aagatatcat
    22381 tgctatctta ggtatggatg aattatccga tcaagaaaaa gtgttagttt ctcgtgcccg
    22441 cagagtccaa ttcttcttgt cacaaaactt taacgtggct gaacaattta ctggtcttcc
    22501 aggttcatat gtccctgtag aagaaacagt gaaaggattc cgcgaaatct tggaaggcaa
    22561 atacgatgat cttcctgaag aagctttccg aagtgttggc cgaatcgaag acgtcgtaga
    22621 aaaagcgaaa acactaggct actagaaagg ggtgccccat ggatcaatat ttaacagtaa
    22681 atgtggtaac tcctgccggt ttggtctatg atcaccatgc agctatcgtc gttgcacgta
    22741 cgacagctgg tgagcttggg attttgccta aacatgcacc aatcatcgtt ccattgacga
    22801 ttgatgaagt tcgtgtaaaa cgaacagatt cagataccca cgtcgattgg atcgctgtta
    22861 atggcggaat catggaagtt cgtgataatg ttgtttcaat cgttgctgat agtgcggaac
    22921 gtgaacgtga tatcgatgta tctcgtgcgg aacgtgcaaa acaacgcgca gaacgccaaa
    22981 tcgaagaagc aaaagcaaaa caagatacga acgaattgaa acgggcaact gttgcgttgc
    23041 accgagcaat caatcgtatc aaagtatcta agcactcata aaatgagatg cggatgttta
    23101 tccgtgttta agaacagtaa aaagaggtta tgacagaagt ggtcagcttc aagacataag
    23161 aaggaattta cgaaaattgc ttctcaaatt tttgtgaaat ctcagcttat ttttcgaaga
    23221 agctacttct ggaacaccgt atatcagagg ttgtaaaatc agcgttttgt cctgagtatt
    23281 agagaaacaa atggaaaaga gttcctcata ttttgccgtt ttttgagcta ataccgaggg
    23341 tcagatgatt gaacaccgtt tattt
//
LOCUS       DARPZF010000040        23012 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.041, whole genome shotgun sequence.
ACCESSION   DARPZF010000040 DARPZF010000000
VERSION     DARPZF010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23012
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.041"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(260..1492)
                     /locus_tag="SLE65_001950"
     CDS             complement(260..1492)
                     /locus_tag="SLE65_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEI8449242.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSAHHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1747..2316
                     /locus_tag="SLE65_001951"
     CDS             1747..2316
                     /locus_tag="SLE65_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEI8449243.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2494..2934)
                     /locus_tag="SLE65_001952"
     CDS             complement(2494..2934)
                     /locus_tag="SLE65_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEI8449244.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            3092..3856
                     /gene="map"
                     /locus_tag="SLE65_001953"
     CDS             3092..3856
                     /gene="map"
                     /locus_tag="SLE65_001953"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HEI8449245.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3888..4811
                     /locus_tag="SLE65_001954"
     CDS             3888..4811
                     /locus_tag="SLE65_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEI8449246.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            4887..6026
                     /locus_tag="SLE65_001955"
     CDS             4887..6026
                     /locus_tag="SLE65_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEI8449247.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            6019..6819
                     /locus_tag="SLE65_001956"
     CDS             6019..6819
                     /locus_tag="SLE65_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEI8449248.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            6819..7646
                     /locus_tag="SLE65_001957"
     CDS             6819..7646
                     /locus_tag="SLE65_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEI8449249.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            7624..8358
                     /locus_tag="SLE65_001958"
     CDS             7624..8358
                     /locus_tag="SLE65_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEI8449250.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            8458..9324
                     /gene="rfbA"
                     /locus_tag="SLE65_001959"
     CDS             8458..9324
                     /gene="rfbA"
                     /locus_tag="SLE65_001959"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEI8449251.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            9338..9910
                     /gene="rfbC"
                     /locus_tag="SLE65_001960"
     CDS             9338..9910
                     /gene="rfbC"
                     /locus_tag="SLE65_001960"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HEI8449252.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            9932..10960
                     /gene="rfbB"
                     /locus_tag="SLE65_001961"
     CDS             9932..10960
                     /gene="rfbB"
                     /locus_tag="SLE65_001961"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEI8449253.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            11058..11909
                     /gene="rfbD"
                     /locus_tag="SLE65_001962"
     CDS             11058..11909
                     /gene="rfbD"
                     /locus_tag="SLE65_001962"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEI8449254.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            11943..13976
                     /locus_tag="SLE65_001963"
     CDS             11943..13976
                     /locus_tag="SLE65_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449255.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            14020..15299
                     /locus_tag="SLE65_001964"
                     /pseudo
     CDS             14020..15299
                     /locus_tag="SLE65_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
     gene            15509..16315
                     /locus_tag="SLE65_001965"
     CDS             15509..16315
                     /locus_tag="SLE65_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8449256.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            16327..17547
                     /locus_tag="SLE65_001966"
     CDS             16327..17547
                     /locus_tag="SLE65_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8449257.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            17537..19123
                     /locus_tag="SLE65_001967"
     CDS             17537..19123
                     /locus_tag="SLE65_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEI8449258.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            19162..21300
                     /locus_tag="SLE65_001968"
     CDS             19162..21300
                     /locus_tag="SLE65_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEI8449259.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(21668..22651)
                     /locus_tag="SLE65_001969"
     CDS             complement(21668..22651)
                     /locus_tag="SLE65_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEI8449260.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
BASE COUNT         7216 a         3934 c         4747 g         7115 t
ORIGIN      
        1 cgagtctctt ctttctgagg agagacatca agagtcgctg cgctactgct cctgacctct
       61 ctcctcagaa agaaaggcat ggcagttagg ttcacaacgc aaaacattgt gcttttgatg
      121 aggttgaact tttacacaag attgtggact tgactaaaaa aacggtgggg ttgtttagcg
      181 aaataaagga tctaagccaa tagcttagat cctttattct atgctttata ttattttttg
      241 catgtgtgcg aaagtatact caagcccaat cgccatttcg gaaaatcggt actgtagagc
      301 catcttcacg gattccgtcg atatccatct tgtcagatcc taccatgaaa tctacgtggg
      361 tttgacttct attcaatcca gcttctgcta attcttcatc ggacatttct gtaccgcctt
      421 tcacactgaa ggcataagca gaacctagtg ctaagtgatt cgatgcgttt tcatcaaata
      481 atgtattgaa aaagatgatg ccagattgag aaataggtga agggtcaggt acaagtgcga
      541 cttctcctaa acgacgcgca ccttcatctg tatcaagcag ttttgctaag acatcttctc
      601 cttgttcggc agaaaaatca acaacttttc catctttaaa agtaaatttc atacccgaga
      661 tgatggtgcc agcataactc agtggctttg tacttgaaat gtaaccatct actcgatgac
      721 tgtcaggtgc tgtgaacact tcttccgtcg gcatatttgc catgaatttt tctccacgag
      781 cattatagct tccagcgcct tcccaaagat ggtttttagg caatccgata atgatatctg
      841 taccgggagc agtatagtga tgggcagaaa attgttctcg attcaattct tctgcttttt
      901 ttgctaattt ttcatcatgc ttcttccatg ctaagacagg gtcttcttca tagacacgag
      961 tcgttttgaa aatctgatcc cataatgcct caacttgttt ttcttctggc agttctggga
     1021 agacttttgc tgcccattgt ttaccagccg cagccacgac agtccaactg actttatttg
     1081 cttgagttgc cttgcgtaaa ttcattagtg ctttgccatt cgctgattga taagacgcta
     1141 ctcgatggct atctacacca gcaaatgcat cgggatcggc agaaacaacg ctgatcctgc
     1201 ttgctccttt ttcaagccat tcatccgctt gatcgatttt agattgtggt acattctcaa
     1261 tacgatccgt tgcagcatgt aaaagaaatt ctctttggat ctggtcgtca gtccattgaa
     1321 cgataacctc agcggctcct agtttataag cttcttgtgt gatcaatcga gcaaggggtg
     1381 cctgttccac gctgatctgt aaaacaactg tgtgtccttt ttctgtggct acgccagttt
     1441 ctgcaattaa gcgtgcatat ttttttagaa gttcattaaa atcagataac ataataaaaa
     1501 ttcctcctca ccattttttc tggtaactat tagcatgata ccatttaatt atgattcaaa
     1561 caatgaggct ttaaataaaa aaaggaggtt atttttttaa ggttaagttt catgatatat
     1621 gttactactt gctatttcag cttgtgaaga aaatcaaaaa ctaattttgc atatcaaaaa
     1681 aaacatgtta caatgaaatt aatcaatggt ggaagcgtta taaaaaaatt aaggagatta
     1741 aaaaatatgg caagaaaaaa gacgattact agagaacaga ttttggcagc tgcttatgaa
     1801 gtagctgcca ccgatggatt tacacgattt actgcgagaa acatcgcgaa caaaatgaat
     1861 tgttccacgc aaccgattta tcttgagttt aaaaatatgg atgacttgag acaagctctt
     1921 tttgagcaga tctatgatca tttacaatat gaagtgttca ctgttgagca tacagggaat
     1981 acgattatcg atcttgcttt taattatatc cattttgcaa gaagagagaa gaagttgtat
     2041 cgttcactgt acttagaaga atatggtgga ggaaaagaga tgcagaattt ctcttatact
     2101 tactttgtga atacagtgaa acgcgatcca gcttatgtga atctttcaga agagcagatc
     2161 gaatctttgt ataatgggac atggatcata gctactggga tcgcagcttt gatgtcttca
     2221 agcatcatcc atccaactga tgaacagatt gaaaagatga tccaagacag tatagatgct
     2281 atcttgaaat tcaaagaacc aatcgaaatc gattgaatat actcaaaagt tccacaaatc
     2341 agtaggtaac aagagatgtg tcaaaataag gaaaagttcg tttttcttac agcgtatgca
     2401 tttttaactc ccgaagaact cttccatgaa tgcaatgaat aaaagagcca tacagattga
     2461 ataaatctgg atggctcttt tattgcaagt atattaaatt tttgcgacta gttctttagc
     2521 gaaagcttct aaattttcga tatcttcttc ttcagcattc agatccactt taacattttc
     2581 ggctcctttt gatgcgcctg tttttgcaaa agcagcatcg aaatcatcca ccgatttgca
     2641 gaattcatcg taaaaagtat caccagatcc gcagacaccg taaatttttc ccaatagatc
     2701 caattcttgc aagtcttcat aaaagtctac gatctcatca ggcagatcgc catcatcgta
     2761 tgtataagta gctactacgc aaatatctgc ctcctcgaat tcatctgcat ctacttgggt
     2821 acattcgttg atttcgactt cgatatccag attttcaaat gcttctgcaa caatatcggc
     2881 gatttcttca gtgtttcctg tcatgctagc atatacgatt tttgctaaag ccatgatgtg
     2941 cctcctcgtt tataattatt taacaattat gaattatacc aaaacatcat tgaaaagaaa
     3001 ataaaaccta gagacacctg gggaatgtca tttggctaaa tgtatgccgc tatgttaaaa
     3061 tgagagggat ttgtaaaaag gagacgaaaa tatgattact ttaaaatcag cacgtgaaat
     3121 tgaaatgatg gcagaatctg gagctttatt agcagatgta cataaaaatc tgcgtgattt
     3181 tataaaacca ggaatcacaa gttgggatat tgaggtattt gtcagaaact atatcgagag
     3241 tcatggcgga attgctgcgc aaattggctt tgaagggtat gaatatgcga cttgtatcag
     3301 tataaatgat gaaatttgtc atggattccc tcgtaaaaag cctttgaaaa acggtgattt
     3361 ggtaaaagtc gatatgtgta tcgatttgaa aggcggcatt tctgattctt gttgggccta
     3421 tgtagttgga gaatctacac ctgagatcga ccgattgatg gaagtaacga agaaagcttt
     3481 gtacatcggt attgagcaag cacaagtagg gaatcggatt ggtgacatcg gtcatgctat
     3541 ccaaacttat gtagaaggcg aaaatctagc gatcgttcgt gattttattg gtcatggcgt
     3601 tggtcctacg attcatgaag aaccagcagt tcctcattac ggagaagctg gaaaagggtt
     3661 gcggttgaaa gaaggcatgg ttatcacgat cgaacctatg gttaataccg gaacttggaa
     3721 aatgaaaatg gatcctaacg gctggactgc gtatacaaga gacggcggac tttcttgcca
     3781 atatgaacat acattggcta ttactaaaga tggtccaaga attttgacat cacaaggaga
     3841 agaaggcact tattgatcta tccagtcaat aggtacggga gaggtacatg aaagtttgga
     3901 acaaaataaa acaaaatgaa aatctgatgc gctttattga gacgactcaa aagcgcatca
     3961 ctgattcaga aatgagtacg acctctgtcg tcgttgctta ttatttactc ttgtctttat
     4021 ttccattgat tattgctttt ggtaatattt taccgtttct ccacatcgat caagagactg
     4081 tactgaccta tttacgagaa gtgattcctg agaccgttta ccagtttatc ggtcctgcaa
     4141 tcaaagacct tttgacacaa agttcaggag gcttgttatc cgtttctgca ttagcggctt
     4201 tatggtctgc aagtcaaagt atcaatgctt tgcaaattgc gatgaataaa gcgtatggcg
     4261 tagaaaatag aaaaaatttt ttgatcgtcc gtttcttctc actaattgtc attgtcttgt
     4321 tcatgattgc tattagtggg gtaactatcg ttcttgggtt gggacagctg attttggatg
     4381 ctattcagcc aatcgtacaa atacccgtga actttatcga tcagttccaa actttgaagt
     4441 ggccaatcac attggtagct ttatttgtca tcatgttctt gatttattta attgtcccta
     4501 atgctcagtt gaagttgaag acgatcattc cgggcacgat cttcgctact gtcggctgga
     4561 tgctgttatc acaagtgttt agtatctatg ctaggtattt tgcaacgagg atcagcggtt
     4621 atcagatcat aggaagtttt attgtactca tgctttggct taattttgct gctacgatca
     4681 tcattttggg cggaatcatc aatgcagttg ttcaagaata cgtgacgggt catcaaatca
     4741 aaaaacgtcg agatccaagc cgaaaatggt tcaataaatt gaaaactaaa ttttctcata
     4801 aaaaaaagta gaaacaagag ttcttattgt aaatttatat cagtaattta taataattat
     4861 gactcttaat taaagtaggt gcccatatgc ttgtttcttt tagtatggtt ataagatttt
     4921 ttctgacaat tttattatca ctgatattaa cacctgtatt caaaatcatt tcagtacaaa
     4981 caggtatggt cgacaaacca aatgaaagaa gaataaataa agttccaatg ccttcagcgg
     5041 gcggactgcc tatctttatt tcatttgtta tatcgacttt attcttattc cgtaaaatta
     5101 tccctcaatc gtatattgta ccgatcttga ttgcttcttt agtaatcata gtcacaggag
     5161 tgctcgatga taaatatgag ctgacaccta aacaaaaaag tatagggatc ttgattgctt
     5221 ctcttattat ttattttgta gcagatatac gtattgattc cttcacgctt ccttttattg
     5281 gatatatcca actaggctgg cttagttttc ccgtaacgat tttttggatc ttcggtatca
     5341 cgaatgcggt caatctgatt gacggtttgg atgggctggc ggcagggatt tcattgatcg
     5401 gtttaattac gataggaatc attggatatt ttttcctcca tgcttctaca gtgtatattc
     5461 cagttgttat tttctgtctt gtagcaagta ttatcggttt ttttccttac aatttttatc
     5521 cggcaaagat ttatttaggc gatacaggag ctctattcct agggtttatg atggccgtcc
     5581 tttcactaca agggctgaag aacgtgactt ttgtttcatc gatttctttg ctgatcgtca
     5641 tgggagtgcc ggtaacagac acgttttttg ctatcattag gagaaaagca aaccgtgttt
     5701 ctttttctac agcagataaa aaacatcttc atcaccgact aatcagttta ggctttactc
     5761 ataaaggtgc tgtcctgacg atttatgcga tggctttgat gttttctttc acagctatgg
     5821 tcatgaatta tactggaaga atcggaacga tcatattgat tattgccatg ttgtttgctg
     5881 caattttatt atttgaattg attggtctga tcaatgagaa acatcagttt attttaaaaa
     5941 cattgcgatt tttagggaat aaagagtacc gtacgcaagt aaaacagaaa tatttgaaga
     6001 aatggaaccg tcatatagat gaataacaaa ttaaaccagc cgatccttat tagtattgtg
     6061 acggcaaaca gtgataaaat ttttcggaca ctagataatt ttatttcaac tgtaaaagat
     6121 gaaacagcag taaaaatccg aatttttgac aacaattcac ttcccgagta caaaaaaaga
     6181 ctaacagagt ataggaaata tccctacatc gatatctatt ttcatgatga aaattccgga
     6241 tttggttatg gacataatca caatctgata gctagcgatt ctcgctatgg cattatttgt
     6301 aacccagata ttttagtgga tgaagagaca gttacagcat tggtcttgtt attgaaagaa
     6361 catccggaat gtgcgatgtt agcacctaag attcttaatg aagatggaac aactcagcac
     6421 ctcatccgtg agcagctggc tgtttttgat tacgttttgc gctttgtgcc tttcaaatgg
     6481 gtcaaaaaaa agtttgacaa acgactggct gtgtttgaat gccgaggatt gcctactgat
     6541 gctaatagtt atgtacggat gatctcaggt agttttatgg tagctgatat tgataaattt
     6601 aaagagataa aggggtttga tgagcgtttc ttcatgtact ttgaagacaa cgacttgtgt
     6661 ttgagttttg aaaaagcagg ttacaagtta ttgtacacac ccttttatgc agttatccat
     6721 ttttacggga agggtgcgca tcgaaatgca aaactgtttc gcgtgttttt gacttctatg
     6781 atgaaatttt tcaataagtg ggggtggcgt tttttctgat gaaaccagaa atattagtag
     6841 tcgttgtgct ttatcagcaa ctattcagtc aatctccagc ttatggacca ttaagcaaag
     6901 cacttagcga aaagcaaatt cagcttatta tttacgataa tagtcctcaa aggcagcaaa
     6961 atgagctgtt tgaaaaagaa aatatcgttt atcatcatga tccgcaaaat cctggtttag
     7021 cggtggctta taattttgcg ttgtctcaag cagatgaagg aacacgttgt ctcgtcactc
     7081 tggatcagga tacgaggcta gtcgacgatt attttgaact attgcgtaaa gtaaccttta
     7141 cagatgaatg tgttgctgca gttccgatga ttttttctgg gagccgacaa gtttctcccc
     7201 tatattcaga tcgttatatc aatcgtacag ctcaagcagt agaagttgaa ggcccaacag
     7261 ctgaacgaat catggcaatc aattcaggtg ttgcctggtc tgtcaaattt ctaaaaaaga
     7321 ttggcgggtt taatcctgct ttttctttag attttttgga tcattggctg ttttggaaag
     7381 tggatcagtt ggaaaaaact gtggagatcc ttcctgtacg aatggaacat gatctttcgg
     7441 ttttagacta tgaaaaagtt tcaagtaatc gataccgttc tattttacaa gcagaaaatc
     7501 gattttatca tgaatatgat caaaggcatt tatccagtca ccgacgacaa ttattgttaa
     7561 gaacagctaa acagttcttg accgtcaaaa accggcatat ctggcggatg actttgcgct
     7621 catatgttaa gaattggaag gtgtgaattc gtgcgttcgg tttgtatagc tacctttaat
     7681 ggaggcagat atttaagaga gcagttagat agtattttat ctcagctttc agcagaagat
     7741 gaagtagtca tttctgatga tgggtcagta gatgatacat gggatatatt aactgaatac
     7801 gcagaaaaag ataagcgaat ccagcttttt tcggggcctc gtcaaggatt gatcgctaat
     7861 tttggttatg cgatccagca gacgaaagga gatctaatct ttttggcaga ccaagatgat
     7921 gtttggttgg agacaaaagt gaaaaagatc actgactatt ttgagcagaa tccggatcag
     7981 ctagtagtag tttctgattt aatcattgtg gacagcgagc tgcaagagat ccatgattcg
     8041 tatttttcgt ttcgaaattc caaagaagga tggcttaata atgtgataag aagtcactat
     8101 attggtgctg gtatggcttt ccggtcttct ttaaaacccg atattttgcc gatcccgtca
     8161 gaagtgccga tgcatgatat gtggattggt ttgctgggag gaaagaagac tgggttccta
     8221 agagaaccgt taactctgta ccgaagacat gatttaaacg cgagtgagat tgaaacacat
     8281 tctaaattac ggcaaaaaat ttcttggcgt gttcatctga ttacggcgtt gatcaaacga
     8341 aaatggttta aacgttgata aaagatgttt aaatccttaa tatttccatg acaaatataa
     8401 caattgatga gataataaca aagtgaaatt tgaaatcaaa aaggagagca gatatccatg
     8461 aagggaatca ttcttgctgg gggcagcgga acacgtctgt accctttaac aaaggcaaca
     8521 tcgaaacaat tgatgccgat ttatgacaaa ccaatgattt attatccaat gtctactctg
     8581 atgttggcgg gaatcaaaga aattctgatt atttcaacgc cacaagatac accacgtttc
     8641 aaggaattat ttggaaacgg aaatgattta ggactgcaga tcgaatatgc agtacaagaa
     8701 agtccagatg gattggcaca agcgtttatc attggagaag aatttattgg agatgatagt
     8761 gtctgcttgg tattagggga caatatttac tatggtggcg gtctgtctaa aatgttgcaa
     8821 cgagcagctt caaaagatac aggcgcgaca gtatttggct atcatgtcaa tgatccagaa
     8881 cgctttggtg tagtagaatt tgatgagaat atgcaagctt tgtcgattga agaaaagcct
     8941 gctcagccaa aatcaaatta cgctgtaact ggcctttatt tttatgacaa tgaggtaatt
     9001 tctatcgcta aaggtatcaa accttcagaa cgtggagaac tagagattac ggatgtcaat
     9061 aaagcatatt tggataaagg aaaactatcc gtagaactta tgggacgcgg atttgcttgg
     9121 cttgatacag gaacacatga atcattgctt gaagcatcta cctttatcga aacaattgaa
     9181 aaacgtcaga acttaaaagt ggcttgtttg gaagaaattg cttaccgtat gggctacatc
     9241 gataaggaac aattgctggc ccttgcacag ccattgaaaa aaaatcaata cggtcaatat
     9301 ttattgaatt tggccgctga ataaggagtc cttacagatg aaagtaacag atacaaaatt
     9361 aacagatgtc aaaatcgtag aaatggacgt ctttggcgat catcgcggtt tcttcacaga
     9421 aagttattca aaagcaaaat ttgcagaaca tggattgaaa tatgactttg ttcaagacaa
     9481 ccattcacta tcagctgaag ctggtgtcct tcgggggctt catttccaaa aaggagaagc
     9541 tgcacagaca aaattgattc gggtagtcac tggagcagtt ttagatgtag tagtggatat
     9601 ccgcaaaggt agcccgactt atggtcaatg ggacggattt atcttatctg aacataatca
     9661 tcgacagttg cttgtaccta aaggatatgc ccatggattc gttactttga caccaaatgt
     9721 gaacttcctt tataagtgtg ataattacta taatgcagaa gcagatgggg gcatcgcatt
     9781 tgatgatcca gatttagcga ttgattggcc aattgatcca tcaagagcga ttatgtcgga
     9841 aaaagatcac cgtcatccga cattaaaaga atttgaagca gaaaatccat ttgtttacgg
     9901 agaaatctaa gaattaagga gaaattttct tatgaaaaac atcattgtta ccggaggtgc
     9961 cggattcatc ggctctaatt tcgttcatta cgtggtaaac aatcatccag aagtgcatgt
    10021 cactgttttg gataaactga cttatgcagg aaacaaagag aacttggctg gacttcctag
    10081 cgatcgcgta gaattggtcg taggagatgt tgcagatgca gaattagtgg accgtctagt
    10141 aaaagaagcg gacgcagttg ttcattacgc ggcagaatcc cataacgata attcattaaa
    10201 agatcctttc ccatttgtac aaacgaatat cattggtacg tatacacttt tagaagcttg
    10261 ccgcaagtat gatgtacgct atcatcacgt atctactgac gaggtttacg gcgatcttcc
    10321 attacgtgaa gacctgccag gacatgggga aggcgaagga gaaaaattca ctgcggaaac
    10381 accatataat ccttcaagtc catattcttc tacaaaagct ggttcagatc tgttagtaaa
    10441 agcatgggtg cgttcttttg gcttacgtgc aaccatttca aactgttcaa acaactatgg
    10501 tccttatcag catattgaaa aatttattcc tcgccaagta acgaatatct taagcggtat
    10561 tcgtccaaaa ttatatggcg aaggaaagaa tgttcgtgac tggatccata cgaatgatca
    10621 ttcttcagca gtgtggctga ttttgacgaa aggcagaatt ggcgaaacct atctgatcgg
    10681 tgcagacggt gaagaagata ataagaccgt gatggaattg atcttagaaa tgatgggtca
    10741 accaaaagat gcgtacgacc atgtaaacga ccgtgcagga cacgacttgc gttatgcaat
    10801 cgattcgaca aaattacggg aagagttagg atggaagcct gagtttacga acttccgtga
    10861 tgggttggct gacacgatca aatggtacga agaacatgaa gactggtgga aaaaagaaaa
    10921 agaggccgtt gaagcagcat atgccaaaaa tggacaataa tacagagaaa atgtcactgt
    10981 attaatggaa aaacacatgt gaggcaggcg ctcgcctgtc tcttttttaa aataaaaatc
    11041 aaggagcgga taatcatatg tttttattaa ctggaggaaa tgggcaacta ggtacagaat
    11101 tgcgccattt attagatgaa aaaaatctgc aatatgtttc aacagatgca aaagacttgg
    11161 atatcacaga tgccgagaaa acaatggctt acatcacaga attaaaacct gatgttattt
    11221 tccattgtgc agcttacaca gcagtagata aagcagaaga agaagcaaaa gaattagatg
    11281 agaagatcaa tgttgatggt acaagaaatg tagcacttgc agcaaaagct gtgaatgctc
    11341 aattcgtcta tatcagtaca gactatgttt tcgatggaaa aaacaaaaat gtagaatacg
    11401 aagtagacga ccaaacgaat ccactaaatg aatatggtcg tacgaaatta ttaggcgaaa
    11461 aagcagtaga agagatttta gaagactatt atatcatacg aacttcttgg gttttcggga
    11521 tctatggaca caatttcgtc ttcacgatgc aacgcctagc ggaaacccgc gacaaactga
    11581 ctgtagtaaa tgaccagttt gggcgaccaa cttggacacg tactttggca gaatttatgg
    11641 tatatgtcat cgaagaaaaa gcaccatttg gtatttatca tttgtcgaac gaaaatagct
    11701 gttcttggta tgaattcgca aaagaaatat tgaaagatac agatgtagaa gttgcacctg
    11761 ttacgtcaga agaatttccg caaaaagcaa cacgtccgca gtattcagtc atgagcctga
    11821 aaaagacaga agagttagga tttgtcatac caacttggca agaagcactt gcgcaaatgc
    11881 tggaagctgc caaaaaaatg aataagtaat ttccttttat caaatagaat ttggagcatg
    11941 atatggaaaa acaaacaaga agtgcacgac gaaaagaaaa gccaaaagcg aaccaggcag
    12001 attcgaattt ggtgcttgac ctgtttctaa aactccgcta tcttattggc gttttagtca
    12061 tcgtggtcat cgttactttt aatttaaacg gaagttcact tggtgtttgg gataaatatg
    12121 tgtcgcaaag agacgatggg aaaaaaactg atgtgatttt tggacagaat cgggaagtgc
    12181 ggtcagacga atggctggtg cagacacctt tttacctctc acaagctgaa gaggactttc
    12241 cgttggtgaa cgaggattat tcattaaacg gacaaaacat gatcattgcg tataattctc
    12301 ctgtaaagga tattacggtt atcggaaaac cattcaactg gggattcttt ttcctcggaa
    12361 gagatcgagg actttccttt tattgggcga tgaaattagt cgtcatggtc ttgcttggat
    12421 tcgaagtact gatgatatta acgaagagaa aaaaagctct atcgctaatc ggtgcatttg
    12481 cgctgacatt ttctccagca gtccagtggt ggttcatgca acatgtgggc gatttgattt
    12541 tctttacttt gggactgatg actgcttttt atcattattt ctacaatcat gataaaaaat
    12601 ggctacgaac gttgatgatg cttttggtgg ttattttcgg tattgggttt attttagtga
    12661 tttacccagc ccatcaagtg atgctggcgt acttgctgat tttttatttt gttggcctgc
    12721 ttatttacta tagcaagaaa gtttcatggg atctgttgga tgtagtgttg attggagggg
    12781 cagttttatt tattggcgga gtcatggttc atttctggct aacgtcaaaa gacgcattgt
    12841 tagcttcttt gaatacctta tatccaggaa aacgggtaag tactggagga aagtggacga
    12901 ttggcgaatt tttttctttc cttacaaatt ggaaaattcc ttttgaagat atcaactatt
    12961 cgaataactc tgaagtggcc ctgttctatc acttttttcc aactgtattc ctagcaagtc
    13021 catttgtgtt atttggcaaa aaagatagcg aacaaaagtt actgggacgt attttgatga
    13081 ttttttgtct gttttctatc ttttggatta ccgttgggtt gccaaaatgg ctagcagaaa
    13141 tcactctgct gtcttatgtt cctccattaa gagccatcct tacttttagt tttgcggctt
    13201 gtttattatc gatctggttt atcgcttata tttggagaga agatgttatt cctatttggt
    13261 ataaattcat tttgttggca gtaaatgcat ggtcttattt ctatgcgatt acgcattcga
    13321 aaatggataa ttatttttcg gattttgaaa ccatcgcagt tgctgtgttg ggaacagtga
    13381 ttttagcttt tgcattattt ggctggagac gcttgtttta cctcgctttt gccgccttag
    13441 ttatcgtatc tggctttttc gtcaatccag tcgtagaagg tacaggagcg atttttgaaa
    13501 aaacactggc aaaagaaatc caaaaaatcg atcaacaaga tcctggtaaa gtttggttgt
    13561 ctgaagatga attatataac ttcaccccaa cattgggagt gaaatccttc aatacagtac
    13621 gcttttatcc agatatagct gcatggaaga aaatcgatcc gaaagaagaa tacgagaagt
    13681 attataatcg gtatgctcat acaagagctt ttatcgctaa ggaagataca aagttcattt
    13741 tagatcgtcc agatatgttt tcggtcacgt tgaattttga agacgcagaa aaattaggga
    13801 tcgactatgt gatcagtaaa cgaccattaa ctgattacaa ccaattatat gaagcgcagt
    13861 tcacgcagct atatggaccg gataaagacg gttatatgat ttttaaagta gaatatccgg
    13921 attatccaga tgtaccacaa acacaaactc aggaaaatca gctagtcgta cagtaatagg
    13981 ctagctgaga ataatcctga aatgttagta gaaaggagag tggagataat tcaagcaatc
    14041 gtacaaaaat ttgtcaacaa aatgagtgtc ggtttcttgc ttttgttact gacgctagtc
    14101 ttttttgttt ggacagcagg gttaggtttt ccagcaactt tgtttatata taacaatagt
    14161 tcattactta tcgcttttag tgtggctatt ttgctcattt taaatgttta taaagcaaaa
    14221 ggcgtcgatt ttctttatct aggtgttgcg cttgcccttt tcattttctt ttcttacttt
    14281 cgggaattaa gaaatgagtc tttatttgga gacttactgt ttcctttgat tattttattt
    14341 tgtttagtaa ttaaatggat cgagtggaca aaatgggatc gcggtattta tctgattgtc
    14401 ttttcggtct tcctcggaat cacgtttatc gtgtatttac agagatccaa gtaccagaag
    14461 gacaaagcat ctgggctcca ggcaattcgc tttctgatat ttggatcaat acgaatacaa
    14521 tcggaagttc tttgatgact cttgctttat tgatcagtgg atttgccagt tcttttgaac
    14581 gatggtatgt acgaatcatc ggtgcagtag cagttgttgc agcttttctc gggatttggg
    14641 tctgccaatc tagaggtgca ttagtcgcgt tgattgtttt tgcgatattg gatcttttac
    14701 ctaaatcgtt gatgcgtgtc attcgtgcgc catttattgc ttacacggtt acgattcttt
    14761 tagctttgcc gatttcttat ctggcggctg tctctgaaaa agtcaatttg tttaccggtc
    14821 gagaagatat ttggcataaa ttctatcaga cgctaggaga aaaatctgaa caaattttac
    14881 taggaatgaa aacatttatc ttccaacgag gaaaccaatt tttaggaaac cacaatagtt
    14941 ataattctat tttgaatatc tatggattga taggatttgg gattgctgct ttgctgctta
    15001 tcctttttat tggtcgctta acgttgaaag cagatttatc caacgggcag atgactttta
    15061 tctgggcctt ttttgcggtg atgatgcagt catttatgga ggatacattg acttcataac
    15121 catgggttcc gattatttat atcctgttgg ctatggccgt tcatcgatat gatgaaccag
    15181 aagttgcgga ggaattctat gttatggaag aggcatatga cgatatgact tatgatgata
    15241 catcttatga ggaacaacca gatagcgctc attcttccag gatccaacgc tatcattgat
    15301 aggcacaaaa tacgagagag gctgtgacaa ccgtcgcagc cttttttggt ttattgcaat
    15361 tgtctagcat cttctgtaaa atagaaacgt tagagaaaat cttgtatcat agaaaattaa
    15421 gaaagaaata agaacgcagc tcggtaccaa aaatatggta aaatggcact tgactgtaat
    15481 tcactgaaaa tcgcttggag gaacacaaat gtttaaagat ttgtatttat ttatgaagga
    15541 catttatcag aacagaaaat tattgctaca gttttcgatc aatgacttca aatcaagata
    15601 tgcaggatcg tttttaggaa tcttatgggc gtttatcaat ccgctattta ctgtattgat
    15661 ttattggctg gtatttggtg ttggactgaa agcacaaatg atcgatgcaa aatacccatt
    15721 tatcgtatat ttagttaccg ggatgattcc ctggttcttc ttctcagatg catttgcatc
    15781 aactacggtt gtttttcggg aatatactta tttagtaaag aaagtcgtat tcaatattcg
    15841 tatcttgccc acgacgaaaa tcctatccaa tctgtacacc catttattct tcattctgat
    15901 tggcatagct gtcgcgctta taaatggtat atatccttca gcaatgtctt tacagctgat
    15961 ttattattta ttttgcatgt gtgctttctt gacaggattg acttggctga cggcatcgat
    16021 ccaaccattt ttacctgata tcatgcaatt aattacgatc gtgctgcagt tgatcatgtg
    16081 gacattaccg atattatgga gccctaatca gtttgattca ggtcttgtaa gcatattgaa
    16141 attaaatccg ctgtactatg ttgttcaagg ttatcgtgag tcatttttaa gtgaagcttg
    16201 gttctgggag catggaacat atactttgta tttctgggtt ttcacgttag taatgttcgt
    16261 aatcggctct gcagtgttcc gtagattgaa accacatttt tcagatgtgc tgtaaggaga
    16321 atagctatga cagaatatgc aattagacta aaagatatca caaaatctta taatatgtac
    16381 gcaaaacctt cggatcgatt tcgtgaagcc ctcaatcctt ttaagaaatc ctatcatgat
    16441 gtattttatg cgttgaaaaa cgtgaatgta gaaataaaaa aaggtgagat gatcggtttc
    16501 gtgggagaaa acggatcggg aaaatctaca atgttgaaaa tcattacggg agtactgaca
    16561 ccaacatccg gcacgatgga aatcgaagga aaaatctcag ctttgctaga actaggatca
    16621 ggattcaatc ctgagtattc tggctatgaa aatatctatt taaatggaat ggttctagga
    16681 ttttcaagag aagaagtcga tgaaatggtc gatgatatca ttgaatttgc tgacatcgga
    16741 gaccatattt atcaacctgt aaaaacttat tcaagcggga tgttcgttcg tctagctttt
    16801 gctgtagcaa tcaatgtgaa tcccgatatt ttgattgtgg atgaagcatt ggcagtaggc
    16861 gatcttgaat ttcaactaaa atgtatggaa aaatttacag aaatcaagaa ctcgggaaag
    16921 acgattttat tcgtttctca tgatatcagt tcgattcgtc gtttttgtga tcgttcctat
    16981 tggttgaaaa acggagaagt cgtcgaatat ggcgatacga tggaagtaac gacgaattat
    17041 gaaaactttt taaagaaaaa atcagttaaa acagtggatc ggaataaaaa ccaagtagaa
    17101 cggttcgccg ctccagatat cgtcgacgtg acgaaagcgg aattgttgga taaagacaaa
    17161 aatccggtgg atatgctgga acaaggagaa aaactatacg ttaaagtaac ttatgaagta
    17221 aaagatgata caatcaaaaa tccggtttta ggaattgcgc tacgaacagt cgacaatttt
    17281 tatgtatgcg gacttaatac tctactagat ggtatcaaga ttccttggaa aaaaggagag
    17341 aatatctttt atctggagta tgaaaagtta ggtttgttag ctggtgaata ttattttgac
    17401 gttgcggtct ttgaagaaaa tgcaacggtt cctttggtat ataagacaaa gtacatgaac
    17461 ttgtttgtca gcggttctta tatcggagaa ggcatcgtgg tcttagacca taaatgggaa
    17521 gaagggactc atagcaatga aatatgattt tgaaatggac ctagatgaac aaagcagtgt
    17581 gggaaaaatt gccgcacaga tcaaaccagg aagtaaagtt ttagagtttg gtcccggaaa
    17641 cggccgatta acgaaacatt taatcggagc aaaacaatgt gaagtgagca ttgttgagtt
    17701 agataaggaa ttgttcgatt ttgtcagcga atttgctcaa gatggatttt atggtgatat
    17761 cgaaagtttt gagtgggcaa actattatgc tggacagaca tttgattacg tcttgtttgc
    17821 ggatgtttta gaacatttgg tagatcctgg aaaaacattg aagaaagtca gagaattttt
    17881 gaatgaagaa ggagagatcc tgattacatt ccctaacttg gcgcataatt ctgtcatgat
    17941 cgatttgttc aataaccaat tgccgtgggc ttcttatggt ctcctagatg aaacccataa
    18001 ttctttttat actcatgatg gcttccaaaa agtttttgaa aaagcgggat tattcattaa
    18061 tattgaagat tatttgtact tagctgtagg tgatacagaa ttaaaatcaa cttatgaaga
    18121 attgccggaa gctgtacgct atgatttcaa aatgcgacca tttggtgaag tctaccaata
    18181 ctttttctca ttgatgaaac atccagtagc acaaagttcc attgcagagc cacaaaattc
    18241 taattatgta aaagtgttag aagtaaccca gcaaacgaaa caagatgaaa caatccaaca
    18301 aataccattc aataatttca caggggaaaa tgagacacta agtttccccg tatcagaaac
    18361 aacagaaaga atggtgtttc gcttcgcgca acaacctagc tttatcgaat tcagcgcaga
    18421 agctgccgga gaaaaactaa catttatcga ttcgaatgct gtagtcaaaa cagtaaatga
    18481 ttgttatttg tttgatggga aagaattacc agagttcgtt ctaacggata tttctgggaa
    18541 agaagtgact atccattgtc actatcgctt tatcggggaa ttgacaccaa caatgaaaga
    18601 attgttggaa acgattcgtc ccatggctga agtcacaaag cagctttctg agaaaaatga
    18661 cgaattagaa agagaaaatc atcatcttct tgaggaaaat acaagactag accatacgtt
    18721 aaaaacaacc acaaatcgct attgcacatt gttggaaagt gatgaatgga caataaaaca
    18781 tagactagga cgacgtaaga aagaaacttc gaaaaaaatc caagaaaaag aactttctat
    18841 atgtattgac gagaaaatct gggatgcaga aacaaaaata ttaaaaatca tcggatgggg
    18901 aatcgctaat tcggatcgcc agcccttgtc ctataagtta tcagctgacc aatcgccatt
    18961 tttcgaagca attcctgttt cacgagaaga agtcaatcaa gcagaacagc tcgcaaaagg
    19021 aacagaagcg ggatttgagt tacgaatcct ttgcgagcaa gaacgttcat tcttagtgga
    19081 agcagtagct caaaatggcc aatcatggat cattgaaatg taaataatga ttaacttata
    19141 aagataagga gtaaacgaat cgtgcaaaaa aaagaaattg ccgtatttat cgatcaaatc
    19201 actcgtgaac gggccactgg cgatttgctt attgtgggct gggcaattga tgaagtgacc
    19261 aaagaaatcc ctacgataaa ggtagaaaaa gaaaatgtga ttgctgaagc aacacatgtc
    19321 gtaagattgg atatcaatca tttatataat cttgatgtta agacccaaag cggttttaag
    19381 gtacgtttat cagggaaaat gagaggaaaa gccatcttag acttccaaac agcgagacat
    19441 caaaatggca tagctgtgaa attaaacggt aaataccctt atgatgacgg cattgaatct
    19501 tcatgggaaa gaaaaaaaag attactgaaa aaagggataa attatgcaag gactcatggc
    19561 gtaaaaaaag cgatccgtcg ggtcaaattg gaattgaagc caggatcgat cgactatgca
    19621 gagtggatca gtcgtcatga gaaaccagat ttgaaagagc aaaggaaaga agcacaagga
    19681 tttgcgtacc gtccattgat ttccatactt atgcctgtct ataacgttga aatcaaatgg
    19741 ctcgaaaaat gcattgattc ggtactggat caaacgtatg atcattggga actatgtatc
    19801 agtgatgatg cttctactga tccagctatc cgaaagtgtc tggaatccta tcaagcaaaa
    19861 gatgatagaa tcaaagtcgt tttccgaaaa gaaaatggac acatcagtct ggcaactaat
    19921 tctgcattgg aaatagcaga aggagaattt atagcactct tagataatga tgatgaatta
    19981 ccgccatttg cattatatga agtggcaaaa gtgctaaacg tacatccaga actggatgtg
    20041 atctacagtg acgaagataa aatcgatgca gatggcaatc gctttgatcc gcatttcaaa
    20101 gcagactggt cgcctgatac attgatggga aataattata tctctcactt aggcgtatat
    20161 cgaacaagca ttgttaaaga acttggcggt ttccgtaaag gctatgaagg ttctcaagat
    20221 tatgatttgg tccttcgtgt gacagaacaa atccctgcag atcatattta ccacattgac
    20281 cgagtcttgt atcattggcg gacgatccca ggatcaactg caagtaatgg cgaagccaaa
    20341 agttatatct atgattccgg agtgaaagca ttgacagatg ccctgtctag aagaaacatc
    20401 aaaggaagcg tacgtcctgg cagaatttct ggattttatg agattgctta tgacgtcttg
    20461 caagaggatt tggtcagtgt gatcattcca acgaagaatg gctatgaaga tctaaaaact
    20521 tgtgtggatt cgatcatcga aaaaacgtct tattcaaatt atgaaatcat tattgcggat
    20581 aacggaagta cagatccaaa aatgcaagaa ttatttgcag aatacaagca tcagctgaaa
    20641 gaccgcttta tcgtagaatt gattgacatt ccattcaatt attctcgaat taacaattta
    20701 gcagcagaaa aagcaaacgg caaatacttt ttattcttga ataacgatac agaagtgatt
    20761 gagccagatt ggatgacggt gatggtttct tatgcacagt ttgatcgaat cggctgtgta
    20821 ggagcaaaac tgttttatcc agatgataca acgcagcatg caggagtatt attaggaatc
    20881 ggtggtgttg cagggcatgc attgaataac tatgatcgaa cacattgtgg ttatttcggc
    20941 cgattggtca ttgacgtcaa ttacttagca gtcactgcag cttgtatgat ggtcaaggca
    21001 gctgacttca atgctgttaa cgggtttgat gaaacattag aagtagcatt caacgatgtt
    21061 gacttgtgct tgaaagttta tgaactgggt cgttacaatg tctatgcaca tcaagcagaa
    21121 ttgtaccatt tcgaatctaa atcaagaggt tatgaagata ctccagaaaa acaaagacgt
    21181 tttgctggtg aaatcaaaaa aatgcaagat aaatggccag catatattgc gcatgatcca
    21241 ttttacaatg ataatttaac aaaagaagga atcggcgact tttcgttgag accagattaa
    21301 actataataa aaagctgtta tgttgtgatt cgctcgcaca taacggcttt ttatagtttt
    21361 ttgtcaaaaa aaggcagaag gtgccgactc aaaaaaataa gtcgaggttg ggacagaagt
    21421 gtttaactcc gagaaataag aagaaattca cgaaaattgc ttttcaaatt tttgtgaatt
    21481 tcggcttatt taagaagaag ttgcttctgc tcccaccgtt tattcgtttt taaagaatga
    21541 gacaaaagtg tttcttactt ttgtcccacg ctcttattca tgctcagagc gccaatagat
    21601 acaaaatcat agccaaagtt tcacgaaccc tagctgtcaa agaatcgata ttttatttta
    21661 atataggcta ttttaaaata aatggtttaa ggtattcctc tacaaaagcc actctatcaa
    21721 ttatcatggg tttaaaataa gaagtgatgg agataaccag attgttctta gcgtcaatat
    21781 aaagaacatt tccactatta ccaattgctg aatatatttc gttctcagaa tctaataccc
    21841 accataaata gccatatctc atattttgta agtcttctaa agcactggtt ctaggtttga
    21901 acatctcgtt tatccacatg ggtggtacga tttgttttcc tttatacatc cctttattta
    21961 ggcataatac accaattttt gccagatcac ttgccgataa acacaaacca tatcctgccg
    22021 tcccgatatt tagtggatca caaaaccaga cattggtttt aggagactta tccattgtaa
    22081 actgcttatg ttcttcagct gtttcagcat aataattgac atggtttggt atccctatag
    22141 gatcaaatag atacttattg gcaaaatcaa cagttgttag cttacttgtc tgatacaaca
    22201 agccagttaa tatgtgtaaa cagacagttt gatagttgaa ttcgccggtt ataccttttc
    22261 ttcctcccaa taaatctagt gatgtttttg tccaatcttc acttgaacag acttttgtcc
    22321 atggatcgcc tttacatttg tagggtgctt tcattgttag caagtgcttg attgtaatag
    22381 cgtaaatagt tttctccccg cgtttcactt tatactctgg aaaataatct aatactttat
    22441 catcgatact tttgattaat ccttgctcta aagcaatgcc aatcagcaaa gatacaatac
    22501 ttttcgttgc tgacatgata tgacaagtat cgtctttttt ataaccattc cattcatctg
    22561 tataaacttc taccccatcc ttatatgcga caatttgaca tatatttggt tgtcgaaaac
    22621 caataaaatc atgcaactct tgtttattca taagatatta cctcactttc ttctataagc
    22681 ataatgtcat taaaaatcga tttcaatttt ttcgattctt cacgtaatac aggtattctt
    22741 atggactaga cagcgctttg ggaagatgga ttctctgaaa aatataaagg ttcactttat
    22801 gagtggataa aaaaagcagc aaatacttcg acttctttaa tttaccaaca ttagtgaaaa
    22861 tcgattcatc tggagatttg taatttagag tccttgtctt gattagaggt gtataaagct
    22921 ttttattaga catttttaaa ttccattaca atttgcttat aaactaggtt tttaaaggtg
    22981 actatggtaa gataatagag atattatttt gt
//
LOCUS       DARPZF010000041        22455 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.042, whole genome shotgun sequence.
ACCESSION   DARPZF010000041 DARPZF010000000
VERSION     DARPZF010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22455
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.042"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..210)
                     /locus_tag="SLE65_001970"
     CDS             complement(<1..210)
                     /locus_tag="SLE65_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEI8449261.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
     gene            complement(309..623)
                     /locus_tag="SLE65_001971"
     CDS             complement(309..623)
                     /locus_tag="SLE65_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449262.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            complement(691..1185)
                     /locus_tag="SLE65_001972"
     CDS             complement(691..1185)
                     /locus_tag="SLE65_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449263.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            complement(1178..1492)
                     /locus_tag="SLE65_001973"
     CDS             complement(1178..1492)
                     /locus_tag="SLE65_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449264.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            complement(1708..3099)
                     /locus_tag="SLE65_001974"
     CDS             complement(1708..3099)
                     /locus_tag="SLE65_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEI8449265.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            complement(3084..3695)
                     /gene="mobC"
                     /locus_tag="SLE65_001975"
     CDS             complement(3084..3695)
                     /gene="mobC"
                     /locus_tag="SLE65_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEI8449266.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            complement(3699..3896)
                     /locus_tag="SLE65_001976"
     CDS             complement(3699..3896)
                     /locus_tag="SLE65_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449267.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            complement(3887..6460)
                     /locus_tag="SLE65_001977"
     CDS             complement(3887..6460)
                     /locus_tag="SLE65_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449268.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKF
                     DSNHETVIIDSEIRENDKGSKSRRRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSC
                     N"
     gene            complement(6447..6665)
                     /locus_tag="SLE65_001978"
     CDS             complement(6447..6665)
                     /locus_tag="SLE65_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449269.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            complement(6741..7793)
                     /locus_tag="SLE65_001979"
     CDS             complement(6741..7793)
                     /locus_tag="SLE65_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEI8449270.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDSSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            complement(7946..8272)
                     /locus_tag="SLE65_001980"
     CDS             complement(7946..8272)
                     /locus_tag="SLE65_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449271.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDAGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            8297..9463
                     /locus_tag="SLE65_001981"
     CDS             8297..9463
                     /locus_tag="SLE65_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEI8449272.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            9877..13104
                     /gene="fss3"
                     /locus_tag="SLE65_001982"
     CDS             9877..13104
                     /gene="fss3"
                     /locus_tag="SLE65_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HEI8449273.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVALVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            13217..13531
                     /locus_tag="SLE65_001983"
     CDS             13217..13531
                     /locus_tag="SLE65_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEI8449274.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            13544..13918
                     /locus_tag="SLE65_001984"
     CDS             13544..13918
                     /locus_tag="SLE65_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEI8449275.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            13928..14263
                     /locus_tag="SLE65_001985"
     CDS             13928..14263
                     /locus_tag="SLE65_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HEI8449276.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            14346..15686
                     /locus_tag="SLE65_001986"
     CDS             14346..15686
                     /locus_tag="SLE65_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEI8449277.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            15764..16438
                     /locus_tag="SLE65_001987"
     CDS             15764..16438
                     /locus_tag="SLE65_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEI8449278.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            16431..16595
                     /locus_tag="SLE65_001988"
     CDS             16431..16595
                     /locus_tag="SLE65_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449279.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            16671..17813
                     /gene="dcm"
                     /locus_tag="SLE65_001989"
                     /pseudo
     CDS             16671..17813
                     /gene="dcm"
                     /locus_tag="SLE65_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            17803..18093
                     /locus_tag="SLE65_001990"
     CDS             17803..18093
                     /locus_tag="SLE65_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449280.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            18352..19536
                     /locus_tag="SLE65_001991"
     CDS             18352..19536
                     /locus_tag="SLE65_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEI8449281.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            19533..19670
                     /locus_tag="SLE65_001992"
     CDS             19533..19670
                     /locus_tag="SLE65_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HEI8449282.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            20416..22326
                     /gene="ltrA"
                     /locus_tag="SLE65_001993"
     CDS             20416..22326
                     /gene="ltrA"
                     /locus_tag="SLE65_001993"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEI8449283.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         7324 a         3906 c         4145 g         7080 t
ORIGIN      
        1 taaatcagat acataagccc atgtacccgt tcgttgtaaa taaagttctt cttgtaacaa
       61 ctcccatttt ctcttagaaa tcataatgac gccatcgttc aatccatttt tagaatccct
      121 agtaatttct atttcagaat ttgaatgaac tacttcttgc aacactttac ctatattttc
      181 tttgaagttt gttggagtaa tagtatccaa aatgaatacc tctcttctct atacctctat
      241 tatgaagtgc ccataaaata aagcaagcgt tgaggaataa ttctatcaac acttgcttta
      301 ttaagctttc attttgtagt ttgactaaaa ccaataatct tatttctaaa ctctcgaaaa
      361 acttcttgtg gttgataata gtctggatct atttcaaatg tttgtgagaa taattcattg
      421 aatttttcta ctgaaataat gattttacca ttcttctctc gactgttttc tattatttct
      481 gcttctaatt caaataaatc tagtgacgaa ctaaaatcat aaatcatgtc atattgaata
      541 aaaaaatcaa gaaaaagttg ctcaaactct tccttattta tcactaatgt ttcaaacgga
      601 acaactttat tttcctcagc cattctccca gttccatttt caaaaatcac aaaactgata
      661 ttaccttaaa aactactaac aaaataaaac ttataaagta aatggcaacc caactatgta
      721 accattctct ctacgtacta cgatttggta gtcctgcctt tcaatcggta attcataata
      781 gtaatttact gtttcttctt tgccactttc aatatactct ggattatcca atatcatatc
      841 atactcataa agttcttcac catccttatt ttcaatcgac cattgttgtg gacgtatcgg
      901 attttctgta tcatttataa gtgtataggt cacttgtaat acacgatcat gttgtgcaaa
      961 ttcatttctt ttttcggtca cttcaatatt tttaaatgtt agttcaaccc catctgcctg
     1021 ataagtttca cctattttta aatcttttgt tacaattttt attggctttt cttctggaaa
     1081 atgtctggct ttaattgtta gataacttcc aaaaagaatc aatcctagta gcactaaaag
     1141 aattccttta acgagccact gaaacgggaa gtaaacttta aacatctttt ttctcctccg
     1201 ttttgtattt gttttttaga gaatacgata acttttgatc aatgtcatcc agcttttcaa
     1261 ttacttcatt acttatcatt gattctagtt ctgaaatttt ttgttcaaat ttaatgcttt
     1321 caggatcatt aaatttatta tttgatggac tagctaacac tggtaaattt gaaaccataa
     1381 cacgaaacat atttgccttt gaaccaaaaa ttcctttgtt ttggttgtaa aaattgttga
     1441 atatttcttt agtttcttct gaagccgaga ctttaaaata tggatagttc atttttttct
     1501 tccacctttc tttttttggg agggagtctg tagggagctt gctccctcag agatttaccc
     1561 gccatctgac ttgccagaaa gtagcctagc gtgagcgggg cggattgact ggcaagtaga
     1621 tgggtagctg gcgtatgtcc taaaaactgc ttctttccaa gcaactcttc ataggcaaaa
     1681 aactggaaag tccactaaca agcccattca gaattccatt tcaaaatttt gttgcctttt
     1741 ttgctgattt tcaatcattt gttgtgtgaa ttcataatcc tttttagcac gatacatttt
     1801 tacatcgtca ttcattatgc gactgatttg atagtgaatc tgtttagcag aaggtgtatg
     1861 agaacaattt tcaaaaccct ttgccggtag aaataactct ttctgatcag tctttttaat
     1921 agaaattgtt ttacttttcg cactacgtaa agtttgagga ttcacatccg tatgaagttt
     1981 aatcgtgtat tcttgatcat cttctaaaga cattgtattt acaaaatgct tgtctacctc
     2041 tcgcaagaag tcatcatatt taatgaattt ttcatcgcct tcacggtcgc taaattgctt
     2101 ttgtgcgatg gaatctaatt ccacaaacgg tacatttaac tcaccagttt tgtaatttac
     2161 tccactaatt agcgacataa cttgctctct ttccatatta aaaaaatttt ttatatgtga
     2221 ttcttctaaa ttcttttcaa gttgttcaga aacagattca aatgaatatc ttttccctaa
     2281 ctttcttgca ctaaaagtac gttcgacata ctgacttttt tcttttctag attgtttatc
     2341 tcttcctaaa gtaattaact cacctctacg ctcatagaaa tttacacctt gtttgtaaag
     2401 aacatagcca agtttgttat ttgtttttga aaattgataa acttcaatgt tatattcttt
     2461 tgccaaatga tccgaaaaat cttcaaaaga attcacttcg catttttcca acgttgcttc
     2521 gatcgcattt tgcacaaact cttgataatt aatttttcca tatttcatct tagaaggatc
     2581 gtttgaataa agattggttc tcttttctaa gttttcatag tactcattat tcactgattc
     2641 aagaccatgt tcattgagga cttgatcgtt aatttttcgc attagttcta aatctttagg
     2701 gtcaatacgc aaccttttac atgtttccat gttaatatta ttaatgacaa gatgactatg
     2761 aaaatgatct ttatcattgt gacttgcaac aatgatttgc gaatttggaa aagctttctc
     2821 tgcaaattcg acagctattt cgtgcatttt atcaatactt aactctttag aagtactctt
     2881 atcaaacgaa tgaataacat gaaacgcttg tgctatatct ttagatttat tcatcttggt
     2941 acgtactaaa ttcatttctt gcagtgcttc ctcactatca tcactacaat ttattcctga
     3001 gactgcaaca catttttctt tttttgaagg attagctgca tattgtaata gcgaggataa
     3061 atttttcttg cgtcctttcg atgttatagt agctcccaaa gttgtttcac ctcatctttt
     3121 aaacttgcaa taatctgaat tgagtgaatt aaattccgat caactttttg ggaatactct
     3181 tctttcgtac ccggtctagt ttgcttttct atccaatatt cgaaatattc tttttctact
     3241 tctgataatt taaaaaaaga gggggcactc cgattggact ccaaaaaaat gtcatctgga
     3301 taactaatca tcaacttttt tgctatgcta ttcgcaagtt catctttaaa aatgttgtaa
     3361 cggctagcat caaaactaaa atgtaggctc ttttcttttt tatcttcaga ttcttctcta
     3421 aaatatttag caatgatatt taatgccttt accgcttgat tcaaattgtt accaatttga
     3481 tttaactgtt tggttaaaac taccctatca tcttcagcta acaacggcgg ttcatatttg
     3541 agtcccttta accgctcacg gcaaacgtct gctctagaaa ttcccctttg ttttgcaatc
     3601 aatgtcagtt caagataagt ctttttatcg acacgaaaat ttaaggcctc actatgtttg
     3661 cgattttttt cgtacatttt ttgtttatca tccattgatt atcccctcac atttttttct
     3721 agagagcaac atttgaaatt gctctctatt tcatttttca tctttaattc ttcttgaatc
     3781 atcagttcaa tataattagt gaccgtgatt ttttcatttg ttgcgttctt tactgattca
     3841 cataattcgt caagttctaa gaaatcatgc gtactaatct ttagaattaa ttgcatgaca
     3901 atccccccct tttatttctt aataaattat cgaaaagtgg attaggatca ttaagtgtat
     3961 ctctgaataa ctcattgtct tcataagtga atcttcgtct tgattttgat cccttatcat
     4021 tttcacggat ttcactatca ataatcactg tttcatgatt tgaatcaaat tttttcgctg
     4081 actttctgtc ttcaacgata ttgatttttt gtgttttttc tttcatttct ccactatctt
     4141 tttgaatgtt ctcccgaaca tctactgttt tgaatccttg actacttgta gaattttgta
     4201 cattttctcg aacatctact gtttttggtt gacttgtact gctactttgc agattttctc
     4261 gaacatcaat tgtcttagta ccttgagcat ttgaagaact ttgtaaattc tctcttacat
     4321 caacattccg tccaacatga ccattcagtg aaccttgaat attttctcgg acatctactg
     4381 atcggccacc atgactactt gtagaatttt gtggattttc tttgactaat ttttctaatc
     4441 ctgtatttga atttttagct tcttgaattc tttctttggt caacgcttct tttccgtcaa
     4501 tattagcgcc tgtccgccct tctacacgtt tccttaacat tatttcctcg cgattcattg
     4561 cttcaggcgt gtatttcgct tcatgacgct tctgattaat taattcttca gcagacttag
     4621 cttgaccgtg catagcattt ttacgttctt caatatcttg ttggactttt tgctgaattg
     4681 cgcttgcagg attattattc gattcagcat tatttttcat tgcttcacgc atacgttcag
     4741 aactagacat aattctatcg gcattttcaa ctttagcacc atcttttcta tctgaaagac
     4801 gtgttggcac ggaatcagca tattttccag tttcatcttc tttattttta gctaacatag
     4861 gtttgctatt tttattaata gcggacactg taccatcatc taaaccttct ttaaacttat
     4921 tcttggtatc attagctata tcacgcatac tcttaaatgg ttttgttgct ctttcactag
     4981 ccattgtagc tccatctgaa gctaaaccgg ataatccacg ttcatgggca tatcccaaag
     5041 ctcttccagt tttgccagct ttttttgata gagtttcgcc gaaattcttt tctggttttc
     5101 gatcttctcc ttctccgctt cctttagcac gattaaatcc atttgatcct tttctaaaca
     5161 gcattgcgcc cattccaaaa gcagaagcaa gttgcccata gccttctttg agtccaatat
     5221 caacaccaaa gtatctcatg actgttccac tgcctttgat taaaacaaaa acggcacaga
     5281 tataagcaat tgtttttata aaaatatttg ttgagatacc ttgtcctgag ttcagaaaat
     5341 tgataaacat agcaaacatt gataacccaa atccttgaaa cccaacagtt aagtaacatt
     5401 gtagaatatc tgatagaaca acttttgaac gctgtcctgt ctcaatatct gttgcaaaaa
     5461 caagaacacc taacacacgt ttaaatgcaa gttctagtat tgctgtaatg atcacaaacg
     5521 cgctgaacac ataggcgatt gctaacgctg tcaacccaat tgaaatcccc catagatttg
     5581 cttggtatcg gtaatagcct gatttcaagc tatcagaaaa tgttgataag aagttgtcag
     5641 aaaactttgt agcaacaaat tcattattag aattttcaac taattcataa cgaagattgt
     5701 ccgcaattgg attttctttt tccaatttat caatcacttt atccgttaac acttgtgtga
     5761 gatccgtctg ttgaaaattt tttcgtgtta aattatttcg atcctccgtt ttatcaatgc
     5821 ttgagtactg atctgtttta ttaatatatg ctaaatctgt tactccttgt tttatcaatg
     5881 accaagcgac tccgtcatct gaatttgtaa tcgtagtaga gtccttataa aatgttttag
     5941 caaattgaat accactagaa atcatggttg gcattaaaag tattaatgct atagacatca
     6001 ctacgttcat tccaaccgat tttaaatcca ctgttccttt tccagtaatc attttgtaac
     6061 caacaaacat caatgaaagg atcattaatc caatgacaat tgtatttacg gctgattgat
     6121 aaacattatt tagccctgta ctttcaatga aattgaacaa atccagcaca tctggaatca
     6181 tattttgaat cgaatctgtc acagtaaaca tgccttttac cacagcccat ccgagccaaa
     6241 tcccgaactg actaaggaaa tctccattgt acttttttag gtaaggtcta taaagagaat
     6301 tattcaaaaa ctctgtttga ctttttgtgt catcaaacca attgaaaata ctcgcatgag
     6361 caatattact tgtaaaaata atcatagcta tcagaacaag aaaattaaca accaaccaat
     6421 ttattttttt attggcaatc tttttttcaa ttattttcat cgttacctcc cttagcccat
     6481 tttctgaggc tctcagagag cttctgagcc attttttgat taattatgac atgagttaca
     6541 caattatcat tttcagctct taaatcgaga actatagtgt tgaagcaaat agtctcgatt
     6601 aattcgagac tatctgtatt ttgatctaga caccaaactt gatctattaa acgattttta
     6661 atcaaaataa cccctcctat attcaaagtt ctcaaatgaa gtggagatac ccctccattt
     6721 catttgactc aattctattc ttattgctta tctattcctt cgctgatttg caattcaatt
     6781 agttctaacg ctttattttt tagagaagca aagatataat cgtctttttg tttgatacga
     6841 tgatctgttt ttgctcttcg tatcaagtca cgtaaagtca ttgatagctg ttctctaaca
     6901 tgatctacaa aatacttgtt attacaaatt tcatagataa ttttcagttg aattttttgt
     6961 tctttttcag cagatctaat cgcatatttg aattttttgt accagttgtc gaattgacga
     7021 taatcactat tgctagccag ttttaagcaa ttcacaatac tttctcccca tatttgttta
     7081 agaagatttt cttcaataaa tgtttcgatc aattcttcat ctaatttatt atttttagtt
     7141 gaaagtgatt caagaagatc atcattatgt gattctttaa tatctttact atctttataa
     7201 gacttatata attctagttc attttttgaa ctatcagcaa aattgttttt gtctcttgtt
     7261 ttcattgatg tgtcgcatag ttcaaatttt gaactatcaa cagaatattg atttgttcca
     7321 tagttcaaat tttgaactat caagtttttt tgtctatttt cttgatgggt tatcttatta
     7381 attttataaa catcatcttt gcacagaaca ggctttaaca aataataaaa atttgggaac
     7441 atttgcattt tacttttatt gaagccattt tttcttttca caagaagttt aactttttga
     7501 agttcatcta gtgctgataa gattgtattt tttgacattc ccgaaatttc tacgagattt
     7561 ttgatttcaa atatcaaaaa aattttttga ttctcatcat acaagttatt tttcaatgaa
     7621 agtctatttc tatcttttag taacatataa actaacttag aacttagttt cattttctta
     7681 tatttttcat ttacgtttaa aaaaatagga tattgatagt ataattctgc atatatatca
     7741 gaattagaat agccttgctt ttcaactaag ctttcaactt ctttttcatt cattgtcaca
     7801 cctgcttctg attttatttg ctataataga ttcaaataaa gttttctcag aactttatta
     7861 ttgagtgttc ccccgatctg caaactgacg ggaacactct ttttaatttt ttctacttca
     7921 tcaaatttaa aaaacgaggt gttttttaaa tttgatgact caatatccat tttttgcatt
     7981 cttcttttga aaacaactcc attttttcta ataaaataac tggcaatccc attcttttaa
     8041 atttcaaaaa agttgtatat gatacattca aatatttagc catctctttt ccttttagaa
     8101 atggtctttc taatccggca tcaattcttg cttgatcaat agcctctttt gtcatttcaa
     8161 aaacataatt tttcaattga ttcgtttgtt gtttatctaa cattactgta attcctgcat
     8221 ccattatttt tctcctctca ttttctattt cttcaatcag ccaactcgcc aagttatcag
     8281 attggagaga ttagttatgt caatacaaaa gtacacaaca aaaagcggtg cacgatatag
     8341 tgtccgcttg tatgttcgta aagatgaaaa tggaaagcaa gaatactatg taaaaaaagg
     8401 gtttaaaact gaaaaagaag ccaagttaca cgaagcaaga aaaaaggtcg agattgaaga
     8461 taccggctat cataagcctt ctaatgactt gtttataaca gtgtatgaag aatggttgcc
     8521 ttcttatagg aatcgtgtac aagaaacgac atatcaacgt acaaaagacc ttttccgctt
     8581 gcatatacta ccaaaattcg ggaataagtc catttctaag attactcctg ttcactgtca
     8641 gaatgcagtc aatgaatggg ctttaaaatt caagaatatc aaacagctta agtcttacag
     8701 ctctcaaata tttgagtatg ccatttttgc agagctatta caccgaaatc ctatggcaaa
     8761 tacaaatcta ccaaagcggg aaaagaaaga aaatgaaaat tacttttcat tagaagaact
     8821 aaaagctttt tgggatattc tcaataaaga agagccttta aaacatattt taatcttcca
     8881 gcttttgatt actactggta tacgtaaagg agagctagct gctcttcatt ggtctgacat
     8941 ttattttgaa gaacagctaa tgtatgttag aaagagctat gcaactattc gaaatgaaga
     9001 gaagaatgca agaagaaaaa ctgtcaggat tcaaaaaaat acaaaaaata tatcttccga
     9061 acgaatatta ccaattgatg cacaaactat tgaaatgtta aaaatctgga aaaaagaaca
     9121 agctcgagag cttttgcagt ttggcataaa tacaaataca aaaaatcaac ttatctttac
     9181 ctatgtaaat gcagacggtg acattaatca acctttgcat gcggactatt caaataatat
     9241 attgaaacgt ttagagaaga aatataaatt taagcacgtt actattcatg gattccggca
     9301 cactcacgct actcttctac tagaaggtgg agcaagtatc aaagaaacac aagatcgatt
     9361 gggtcataaa aatgctgaaa ctacccttaa cacttattct catgttactg aaaaagctca
     9421 acgaaatgcg ttagaaaaat tcattgctta cactggttta taatattgtc attacctttc
     9481 tcattaccag aacgaaaaaa agacaccttc tcgcaatgag aaagtgtctg aaatcgttgg
     9541 tataacaacg attaacgttt tgaaaactgt gaagctttac gtgctttctt aagacctggt
     9601 ttcttcgtat cattgaataa gtttgaaaaa ccttgattta taaaggtttt cccgtaaata
     9661 tattttatta tatttgatta aatttgaaat gtttgtgttc taaaatgtgt tctaatttaa
     9721 aggcagtata tttcgtattt tagattaaat ttttaggctc attcattctc aaatccattc
     9781 tattcagtca ataaaaattt taaaaagact ttataaacaa agatgttcaa gcgagcatct
     9841 tatttttttg tgcttaattt gaaaggagaa catttcatgt ataaaaaaca aaaaaagaaa
     9901 ttatgtgtat taactatttt gagtttggct gttcaagcaa ttgttggagc aattgctcct
     9961 acgattactt ttgctgatga aattacccat ccacaaacgg taaccgtaga actagattta
    10021 gcacatcaat atgctgttga aggaactttt agtgatggtc gtccaatgtc agaagtcact
    10081 gttccgcatt atgcagtgta caacggcttt aaacaagata ttttctgtat tgaaccagga
    10141 gtcccgattt acaatgagtt cactcctggc tatgagaaaa acccgttacc agatatgtcc
    10201 gataaagcca aattagtttc cgttttatgg aaaaaagtag gtacagatgc agatactcat
    10261 attgtggcac agaagatgat ctggcaagaa gttaatgggt atacccttca ctcaataaaa
    10321 cgatcagatg gtagtgccgt aaatatcgca gccattgagg caaaaataaa tcaagccatt
    10381 gacgattatc agaagaaacc aaccttccat aatagtacgg ctaaaacagt attagggcaa
    10441 tcgactactg tgacggatac gaataatctg aatttgtcag agttcgatga ggttgtggaa
    10501 aatgccgcaa acattgatta tcgtgtgaat ggtaatcagt tgataatcac cccaaatgcc
    10561 aattcaaaag aaagtggtgt gctgacgctt aagaaatctg ctggtaccgg aacacctgtc
    10621 gcctataaaa aggctggcca acagacttta atggccgggg cgattgataa acctaatacc
    10681 tacacaatca aaattgatgt ggaaacggag ggttctttaa agatcaaaaa agtcgataaa
    10741 gaatcgggtg atgttgtacc aggaacggtt ttccatttag actttggaaa aactttacct
    10801 gcaaaagacg tgactactga caaagaaggc attgctacat tggatgagat tcctcatggt
    10861 acaaaagtaa ccattaccga aaaatcagta ccggcgcctt atacgattga taccaccccc
    10921 atgactacca ccattaaagc aggcgaaacc atttacgtga cttcaaaaaa cgcacgggaa
    10981 aaagggcaaa tcattctgga taaaagcgga gttgaaacag ggagtgatct ttggaatgac
    11041 aattattcct tagctggtaa tacgtttgcc attcgcaaag acagtccaac cggtgaaatc
    11101 gttcaagaaa tgaccacgga tgaaaacggt catgcggaaa caccaaaaga gattgctaat
    11161 gcgttggaat tgggaaccta ttatgtgacc gaaactaaag ctagtcatgg gttcgtgaat
    11221 acgttcaaac ctgtaaaagt cgaattgaag tatgccaatc aaaccgtagc ccttgttacc
    11281 agtaacgtaa aagggcaaaa tcaagaagtc actggcgaaa ccactttgac gaaagaagac
    11341 aaagatactg gggataaagc acaaggtaag gcagtctttg agggtgctga atacaccttg
    11401 tttactgcta aggatggaaa agctgttaaa tggagtgagg cttttaaacc agagttagcg
    11461 aagggaacga aaggttctga tgaaacggtc actttgactt tagacgaaaa gaaccaagtt
    11521 gccgttaaac atttagctat caacgagtat tattggcaag aaacaaaagc gcccgaagga
    11581 tatagccttg atgaaacaaa gtatcctgta tccatcaaaa aggtggatga tagcgaaaaa
    11641 aatgccgtga ttacccgaaa tgttacggca aaagaacaag tgattcgctt tggctttgat
    11701 ttctttaaat ttgctggatc agctgcgggc actaccgaaa ctggcttcaa tgatctgacc
    11761 tttaaagtgt cgccattgga agggaccaat gaaatcacag gtgccgaaga tgaagcgacc
    11821 acagcttata acgagcaatt agggtttgat ggttatggca agtttgaaaa tcttccttat
    11881 ggggattatt tacttgaaga agtagaagcc ccagaaggtt ttcaaaagat tacgccatta
    11941 gaaatccgtt ctacttttaa ggaaaacaaa gaagactttg tgaagagtga gtatgtcttt
    12001 accattaccg aacaagacca aaaacaacca attaaaacgg tgaccgttcc ttacgagaag
    12061 ctgacgaaca aagcattttc tgttagtttg aaccgtttaa tgctctatga tttgcctgag
    12121 gaagaagata gtttaacttc tcttgcgact tggaaagacg gaaacaaaga attaacttct
    12181 ctggattcta ccgagctagt tgataaattg agttacaatc tacatgaaat caaagaagac
    12241 tggtatgtgg tagcgcaagc cattgatgtg gatgcgacaa aagctgccca agaaaaagat
    12301 gaaaaagcca aaccagtggt gattgcagaa acaagcgcaa cgttggcgaa caaagagaaa
    12361 acaggaactt ggaaaattca gcataaatta accgccgaac aagttttaaa taaaactatt
    12421 gtcttattca actatgtgta tgaaaataag gaagcttttg aagcaggcga taagccagta
    12481 gcgaaggatg ttagcttgaa taaccaagcc caaactgtca gttgtacagt ggaacaccat
    12541 gtttctatcc aaacaaaggc ccacctagaa aacggttctc agacctttac tcatggtgat
    12601 gtggtggata tgtttgatga tgtgtcgatt actcatgatg tactggatgg ctcaaaagaa
    12661 gctttcgaaa caattctgta tgctttatta ccggatggta caaacaaaga aatttggaaa
    12721 tctggcaaga ttgattatga agtaaatgat aaagaattca ccaaaactgt gcttgcgaaa
    12781 aaagtagata ccggaaaata tccagaagga accaagttta cttttgcgga aatcaattac
    12841 gataaagatg ggaatatcaa tggaaaacac aatgaagatt tgaaagaaaa atctcaaacc
    12901 ttaacaccaa aagaagttcc aaccatacta agtacgccga aacaaccgga aacaccaact
    12961 gttccaagtg gctctcaaga atctagtccc acagtgaaga ccttccctca aaccggggag
    13021 aaaaattcca atgttttact gttcattggt tttactttga tttttgcgac ggcgggctat
    13081 tatttctgga atcgccggaa ctaaggtgat gagatgatac aagtaaatcc taagaaccaa
    13141 cgtgcgcgac cgcctcctaa aaaagtagtc gcgctatttt tgtatccaaa actaacaatg
    13201 aaaagaggaa aagaagatgg aattgaaatt tgtcgtgcca gatatggctg aaacctttgg
    13261 aaagttaagt tatgccggtg aaggagaaat tataacagaa ggatatggac ggaatactac
    13321 ggtgattggt cgcagttatc atttgtattc cagtaagcaa cgggccgatg atattgaggt
    13381 ggtagtagct gcggaagccg gtgaaaagga ttttgatcaa gaccaaccgc taaaagccgt
    13441 gaatccccat ttggttgcca aaggctatga gattgagaat cgtgggttta ctgattacgt
    13501 gttgtatgtt gatgatttag tgaaagcata ggaggaaaag aagatgagat taacagaagg
    13561 tattgtcgta gattcaggtt taacatttgg gaagttgcgt ttttccgcat tacgccgaga
    13621 agtacggaag caaaatgagg atggaacaat tggtaatgag gtaaaagaac gaacctataa
    13681 tttaaaatcc tctgcacaag ggcgaatgat tcaagttagt atcccagcta atgtaccctt
    13741 acgcgagttt gcttatgatg cagaggtaga gttggtcaat ccaatcgtgg ataccgttgc
    13801 caattatgtt tttcgagaag gaactaccgt taattggttc attaaggcgg atgatttagt
    13861 cttgaagcgg cagccgaatc aaggaaatcc tacgaaccaa aatgaaagaa agaaataggt
    13921 gaagattatg gaaattaatg ttgaacatat tttagattgt ctcgatcaat atggaaaagg
    13981 cgagctgact gaggaacaac tcgttaaagc attaacctct gatgaaaaaa tgtttctgat
    14041 tatacatcaa ggtttacttg gagaaaatag cgacagtgaa gaagactctg atgtactaga
    14101 ctggttagga gaagaagagt ctttctttat agttgtcgaa gtaaatgaaa acttatgtcg
    14161 gcaggcagaa tccattttgg aagaaattgg tgtggagatg ccggatgcta ttgaaggctt
    14221 tttaaatcaa ttggttgaaa cgaaacaact cccctcctcg tagcagtaaa tgactagcat
    14281 aactttttga aattgcctaa tgaaatccta ttgggctttt tcgattggag gtggaaacca
    14341 tcaaaatgta caaaggacat cgcatacgcg caggagatca gcacttggtt tatcactttg
    14401 ttcttggctg gctactcgct ctgttcatcg gttggatgag cgtcttttat tttcaagagt
    14461 ttagacaatt tgatatttct aagctatcac tttctactat tgaaatcgtt tggtctataa
    14521 aagatttagt atgtctgctt ggaagtctcg ctttttcagg agctatgata ttgctttata
    14581 ttcacttttt tcttgatcat tggcgaagct tgtggcatcg acaaaagcta gctcggatga
    14641 ttctagagaa ccattggtat gaagtgaaac aaactcaaag tgaaggcttt ttcaaagatt
    14701 tgaatagtag ccgaaccaga gagactatca gttacttccc caaaatctat tatcgaatga
    14761 aagatggatt actgtctatt cgcgttcaaa tttcacttgg gaaataccaa gatcagcttt
    14821 taaaattgga aaagaagtta gaaagcggac tgtattgtga gttagtagaa aaggaactca
    14881 aagactccta tgtggagtat actttactgt atgatatgat cgccaatcga attgggatag
    14941 acgaagtagt ggcagaaaat gggactctgc gattgatgaa aaatcaagta tgggcttatg
    15001 attctttacc ccatatgtta atcgctggtg gcacgggtgg agggaagacc tatttcctcc
    15061 tcaccattat cgaagcacta ttgaagtcag atgcagaatt gtttatcctc gatcccaaaa
    15121 atgcagattt agctgattta ggtacggtga tgcctcatgt ttattcacaa aaggaagaaa
    15181 tttctgcttg tgtggaagat ttctatgaac gtatgatggc tcgtagcaag gcaatgaaag
    15241 aaatgtctaa ctacaaaaca ggagagaatt atgcctatct tggacttcca cccaactttt
    15301 taatctttga tgaatacgtg gcttatatgg agatgttaac gacgaaagaa agtgcggtga
    15361 ttttgaataa gctcaaacaa atcgtgatgt tgggtcgtca atctggtttc tttctgattt
    15421 tggcttgcca aaggccggat gcgaaatatt taggagacgg aatccgcgat caattcaact
    15481 ttcgcgtggc tttgggtcgt atgagtgaac tcggatattc catgatgttt ggggaggtcg
    15541 aaaaaaactt ctttatgaag cacatcaaag gtcgaggtta tgtggataca ggtggcagtg
    15601 tgattagtga gttttatacg ccacttgtac caaaagggta tgatttctta gattcaatta
    15661 gtaaattaga aaagatgaat gattgagtga tcttcaatac tgactttata cttcaagtaa
    15721 cgtataatac ttttatatag taggaagaaa ggggataatt aatatggaaa gtaatgattc
    15781 ttatttagag tatgcaaaag caaataagga taagtttatt tcttatatta tcaaagggaa
    15841 atcccccgaa gttggacgag acgcagtttt tatggcaggg agtcctgggg ctggaaaatc
    15901 agaggttgcc attggattag ctgagaatta tgataaccat gtgattattg atgcggatta
    15961 ctttcgcacc cagtttcctg attataatgg aaaaaactct agtctctttc aaaaagcatc
    16021 ttcttggttg gtagagcagg catttagata tgtcttagat catggctatt cttttattct
    16081 ggatgcaact tttgcaatat taagtgctga aaaaaatatc tcgcgggcgt tgaaaaaaca
    16141 ttttcgagtg acgattttct atgtttatca agaccctaaa atcgcttgga aatttacaca
    16201 agaacgtgaa attgcagagg gacgtcatgt gccgaaaaag gcatttatta acgctttttt
    16261 caaatcaaga gagaacattg caaaagtaaa gagtaaacat ccagatgtat tgcttcatat
    16321 cataataaaa gattatacga ataatatttc cgaagttcat tatgctacgg ataatctaga
    16381 attattttta ccactagggt atagtaggaa agatttggag gttcaattac atgactgaga
    16441 aagaacaagt aacgaaaatt gtaaagaaat acaataagag cattgcggat ttatcggaaa
    16501 atgctactgc aaaagagttc aaaacggtga ttaaatatgt agccgatcag gccaatgaaa
    16561 aacaacggaa attagttgga ttaaataaaa aatagtagga caaattaata atgtatgagc
    16621 caagagcaaa atgttcttgg cttttttctt tgcaatgaat gaggtaatgt atgagatttt
    16681 tagatttatt cgccggtatt ggtggctttc gtttaggtat ggaacaggcg agccatcatt
    16741 gtatcggttt ttgtgaaatt gataaatttg ctagacgtag ttataaagca attcatgata
    16801 caagtaagga ggtggaaatg catgacatca caagtgtatc agatgagttt attcaatccc
    16861 tcggaccagt ggacatcctt tgcggcggat ttccgtgcca agctttttca attgcgggaa
    16921 agcggcaaag attttccgat actcgaggta ctttattctt tgaaatcgct cggttcacca
    16981 ctcttctccg acctaagctt ttattccttg agaacgtccg aggattgctc aatcacgaag
    17041 gaggggctac gttcgagacg atcctccgaa cgctggatgg attggggtat gacgtggagt
    17101 ggtaggtgct taactcaaag gcctacattc cccaaagccg ggagcggata ttccttatcg
    17161 gacattctcg agacgcatgt accgaacaag tatttcctat cattggaccg tcttcaacat
    17221 ctgatcaaaa catcagaaat ttggtaaata tcaatccttc caatcgagga atgggtggac
    17281 aagtctatgg ttcagatggc gtagcgccaa ccttaacagg tgatgaagga atcaaaatcg
    17341 cactgccagc aagggatgga atctctgtag caggactatt accgggaaag tttgaacaag
    17401 gtaatcgagt ttatgaagtt actggaaccg cccccacctt gtcaacgaaa caaggtggta
    17461 caaaaatcat gattcgaaaa aatgaaacag aatatcaaga ggtgaagcca gaagacagtg
    17521 tgaatctggc ttttcctaat tccacaagtc gccgaggtcg tctgggaaaa cagagtgttc
    17581 ataccttact aacaggagac caacaagcga tcgtcacgga tcagtatcaa attcggaagc
    17641 taacacctag agagtgttgg cgacttcagg gctttcccga ttgggctttt gatcgagatt
    17701 ctcaagtcaa ttcagatagt cagttgtata agcaagccgg aaactctgta acagttccgg
    17761 tcatttttga tattgccaga agattaaaag agttggatgt acatggttta tgatgagttg
    17821 attggagaaa tttattgggt gattggaaag attcagtcag acccagaatt agaagaacaa
    17881 ttgcgacggt taaaatttga tattcgcaag aatggtgtca aagtcgctgg cgatccatat
    17941 ttaatgaatg aggagacgga tgctcgaatt gaaataaatc aagtaattgc agaatttgag
    18001 cggattgcgg accaagcaaa agaaccagat attcgtcaat acttgttaga aatgaaagca
    18061 gagttggaag taaatggtat tacagatgag taacctaaac caacacaact gactgttagg
    18121 cgctgaccgc ggaggattcg cgaagcagaa atcctccgtg gtgctgtgcc tgttcatgga
    18181 cggcgttagc cgaccatgat gtctcacccc cgtatctaac aggggggtac aaaaacacaa
    18241 aaaataagta agcaaccatt aagaatgctt gttgtatcaa agatagtaag taatttgtat
    18301 aggtgttaac tcatttgaaa aagttaacac cttgaatttg gaggtgagaa cttggcacaa
    18361 cggaatttag attatcggct attaaaagac cgacgcaacg aatacggcgt ttcacaaaat
    18421 aaattggcta cggcttgtgg acttagtcgg ccgtacttaa atcagataga aaatggtggc
    18481 gtaaccgcat ctataaaaac catgaggaaa atttttgacc aactggaaag ctttaatccc
    18541 gatttgcctt tgacgttact gtttgactat gtaaggattc gctttcccac aacggatgca
    18601 cgaaaaatta ttcaagaaat tctccatttg aaatttgagt atatgctcca tgaagattat
    18661 gccttttact cctatcaaga acagtatgtc atgggtgata ttgtggtgat gttgtctcat
    18721 gaagaagata aaggtgtgct tttagaatta aaggggcgag gttgccgaca atttgaaact
    18781 tttttactcg ctcaaaagcg tagctggtac gactttttcg aggattgtct aaaggccggt
    18841 ggcgtgatga aacgcttgga cttggcaatc aatgatcgag tggggctatt ggatatacct
    18901 gagctaacga aaaaatgtca gaaggaagaa tgtatctcct tgtttcgtac ctttaaaagt
    18961 tatcgttccg gggaactttt aaaggctgat gaaaaggacg gcatgggcaa taccttatat
    19021 atcggcagtc tcaagagtga ggtttatttc tgtttgtatg aaaaagacta tgaacaatat
    19081 atcaagttag ggattccatt agaccaaact gagacgaaaa atcgttttga gattcgactg
    19141 aaaaatgacc gtgcttttca tgcgattcaa gatttgttaa aaggtcgtag cattgagagc
    19201 accacgtttt ccattatcaa tcgttacttg cgatttgcgg ataaagtaga aggtaaaagg
    19261 cgaaccaact ggcccttgaa tgaacaatgg gggcgtttta ttggacggaa tcggaaagag
    19321 attcaattaa cttccgagcc aaaaccgtat accattgaac gaaccttgaa ttggctaggc
    19381 cgacaagtcg cccctacgtg gaaaatggct aaggagttgg atcgattgaa tcggacaacc
    19441 tatatccagg atatggtaca gaatgcacgc ttatcagacc gacataaaaa gattttggag
    19501 caacaaagta tggcaattga aaatttgatt atatgaaaag aggaatcgtc atgggaattg
    19561 taaaagatat ttttttggta tttggtggca gtatgcttgg tgttactgtg atgtgcttga
    19621 tgaatgcaag tgcagcagcg gatcgagcaa tggaaaagaa aggaaagtga caagatgaat
    19681 ttcggacaaa atttatgtgc gactcgttcc ttagtgaaaa gctaaggcac taataaaaga
    19741 acgaaaaagt ttggttatta ggagaactga taatctgaca ggtggaatga tgaagtaacg
    19801 ctctgaaacg cctgccctga gcctccgaca agcattgtat gaggaaactc agaatgtttg
    19861 aagctcggta aagacggctg aaagataccg taatagttga tgaacatata tcttctatcg
    19921 aaaactatcc agaggtgggt agcgtatcca acaggtcggg ggtctataaa atatctatgg
    19981 ttagaatgtt ctataaggaa ctgacgaaac agcgaatgta cgggtctaaa tttgaacttt
    20041 gtagaaatgc aaaggtacga gaaatcgtag ctggtgtggc aaagtaagaa tataggttat
    20101 gaaatgccat ataacgttac aggcggtatc aagccagcag gcttatagct agtgacctaa
    20161 ggatatatat gtatagataa gattatcgga acgaggaaag gtattgggtt ctcatcaaga
    20221 gaataaactg acgaagaaca ataagcagtt gaactaatgc tgaaaagcag agggcgaacc
    20281 taagaaattc ttgtaatgag aatggaggaa tgccctcaag tcgtgtatat attagaaaag
    20341 tattatgttg tttcaataag gattacgagt aagataaaaa agctcactca atttcaagta
    20401 aaggagtgaa gccttatgcc taaaaataaa aatgaaacat tgtgtgtaga agatttaaga
    20461 cacgctgaat attacgaaat gcaaaacacc tttgatgatt tatatgccaa aagtaagaat
    20521 ggagatattt tcactcatct tatggatatt atcctatcga gagaaaatat attactggca
    20581 tatcgaaata tcaaagcaaa tgcaggcagt aaaacagcag gaacagacgg tacaataatt
    20641 aaagatattg gcaaattgcc agcagaaaca gttgtcaaaa aagtaagata cattgttgca
    20701 ggcagtccac atgggtatcg acctaagcca gtgaggcgaa aagaaatacc aaaaccaaat
    20761 ggtaaaacca gacctctagg tattccttgt atgtgggaca ggcttataca acaatgtata
    20821 aaacaagtat tagaaccaat ctgcgaagct aaatttagtg aaaacagcta tggttttaga
    20881 cctaataggt cagttgaaaa tgcaataaaa gcaacctata accgcctaca aatcagccag
    20941 ctacattatg tgattgaatt tgatattaag ggtttctttg acaacgtgaa ccattccaag
    21001 ctgataaaac agatatgggc tatgggaata cgggacaagc acttgatatt cattttaaaa
    21061 aggatattaa aagctccaat caaaatgact aacggtacaa taacatatcc agagaaagga
    21121 actccgcaag ggggaataat atccccacta ctagcaaaca ttgttcttaa tgagttagac
    21181 cattgggtag aaagccaatg gcaggaaaat cctgttacaa aaaactatgt ggttcatatc
    21241 aataaaagcg gtagcccatg taaaagcaac gcttacaaag aaatgaagaa aacaaagtta
    21301 aaggaaatgt atatggttcg ttatgcagat gattttagag ttttctgccg ctacaaggaa
    21361 agtgctgaaa aagccaaaat agcaatcact caatggattg aacaacgatt aaaattggaa
    21421 gtatcacaag aaaaaacaag aattgtaaat gttagaaaaa gatactccga ctttcttggt
    21481 ttcaagatta aaatgatacc gagaagaaag aagttagttg ttaaatcaca tataagtgat
    21541 aaacaattca aaaaccaaaa agacaagctg gtatcacagg caaagaaaat tgcttctccc
    21601 tcaaaaggga aaacggaatt agaagaaaca agactttata attcaatggt attaggtatg
    21661 caaaattatt atcagattgc aacgaatgta aatctggatt gtatgaaact gaatagagct
    21721 gtaatggcta tcttcactaa cagattaggt acaaacaaaa ggggcagatt gagaaaaaca
    21781 ggcagacaac ttacgacaaa ggaggcaaca agatatggta aatctaaaat gcttcggtat
    21841 gttgctggcg agggcgaacc tattttccct gttggatata tccaacacag aaaaccaatg
    21901 gcaaaggtgt atttagcgaa ttgctacact ctagagggaa gaaaatttat ccacaccaat
    21961 ctaagtgttg ataaattact gatgtaccag ttaatgaaat tatctttgga aaatcgcaca
    22021 atagaatacg cagacaatcg aatttcgcta ttttctgctc aacatggaaa atgtgctata
    22081 actctggaag aatttcaaca agctaatgaa atacattgtc atcatattgt accaactgga
    22141 gctggtggaa atgacgatta taaaaatctt attttggtaa aagaggcggt acaccgtcta
    22201 atacacgcta aaacagaaga aacaatacaa aaatatatag ctctattgaa gctaaataaa
    22261 gtccagctca taagactaaa taaatataga gtattagctg gcaatcaaga attaaacttg
    22321 atataggtct actacataaa tacttttcaa tataaacacg atggaacgcg gagtgcggtg
    22381 aaagtcgcac gctccgtgtg aatgggggga aaagtttgag atatttataa tatcaggaac
    22441 ttacctatcc atata
//
LOCUS       DARPZF010000042        22133 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.043, whole genome shotgun sequence.
ACCESSION   DARPZF010000042 DARPZF010000000
VERSION     DARPZF010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22133
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.043"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..524
                     /locus_tag="SLE65_001994"
     CDS             <1..524
                     /locus_tag="SLE65_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HEI8449284.1"
                     /translation="GGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGIVA
                     NCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIFGS
                     LIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILTVL
                     LLPLFFQPFAGLF"
     gene            524..2110
                     /locus_tag="SLE65_001995"
     CDS             524..2110
                     /locus_tag="SLE65_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8449285.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            2129..2350
                     /locus_tag="SLE65_001996"
     CDS             2129..2350
                     /locus_tag="SLE65_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEI8449286.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            2347..3108
                     /locus_tag="SLE65_001997"
     CDS             2347..3108
                     /locus_tag="SLE65_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEI8449287.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            3488..3997
                     /locus_tag="SLE65_001998"
     CDS             3488..3997
                     /locus_tag="SLE65_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEI8449288.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(4072..4611)
                     /locus_tag="SLE65_001999"
     CDS             complement(4072..4611)
                     /locus_tag="SLE65_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEI8449289.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(4751..5362)
                     /gene="rpsD"
                     /locus_tag="SLE65_002000"
     CDS             complement(4751..5362)
                     /gene="rpsD"
                     /locus_tag="SLE65_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEI8449290.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            5624..6475
                     /locus_tag="SLE65_002001"
     CDS             5624..6475
                     /locus_tag="SLE65_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEI8449291.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            6503..7138
                     /locus_tag="SLE65_002002"
     CDS             6503..7138
                     /locus_tag="SLE65_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEI8449292.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            7158..7931
                     /locus_tag="SLE65_002003"
     CDS             7158..7931
                     /locus_tag="SLE65_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEI8449293.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            8339..9136
                     /locus_tag="SLE65_002004"
     CDS             8339..9136
                     /locus_tag="SLE65_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HEI8449294.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            9114..9527
                     /locus_tag="SLE65_002005"
     CDS             9114..9527
                     /locus_tag="SLE65_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEI8449295.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            9511..12156
                     /gene="mutS"
                     /locus_tag="SLE65_002006"
     CDS             9511..12156
                     /gene="mutS"
                     /locus_tag="SLE65_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEI8449296.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            12174..14282
                     /gene="mutL"
                     /locus_tag="SLE65_002007"
     CDS             12174..14282
                     /gene="mutL"
                     /locus_tag="SLE65_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEI8449297.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            14304..14864
                     /gene="maf"
                     /locus_tag="SLE65_002008"
     CDS             14304..14864
                     /gene="maf"
                     /locus_tag="SLE65_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HEI8449298.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(14949..16937)
                     /gene="treP"
                     /locus_tag="SLE65_002009"
     CDS             complement(14949..16937)
                     /gene="treP"
                     /locus_tag="SLE65_002009"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEI8449299.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            17160..17873
                     /gene="treR"
                     /locus_tag="SLE65_002010"
     CDS             17160..17873
                     /gene="treR"
                     /locus_tag="SLE65_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEI8449300.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            17950..18396
                     /gene="msrB"
                     /locus_tag="SLE65_002011"
     CDS             17950..18396
                     /gene="msrB"
                     /locus_tag="SLE65_002011"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEI8449301.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            18566..19168
                     /gene="ruvA"
                     /locus_tag="SLE65_002012"
     CDS             18566..19168
                     /gene="ruvA"
                     /locus_tag="SLE65_002012"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEI8449302.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            19181..20182
                     /gene="ruvB"
                     /locus_tag="SLE65_002013"
     CDS             19181..20182
                     /gene="ruvB"
                     /locus_tag="SLE65_002013"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEI8449303.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            20211..20789
                     /locus_tag="SLE65_002014"
     CDS             20211..20789
                     /locus_tag="SLE65_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEI8449304.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            20841..21323
                     /locus_tag="SLE65_002015"
     CDS             20841..21323
                     /locus_tag="SLE65_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEI8449305.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            21440..21814
                     /locus_tag="SLE65_002016"
     CDS             21440..21814
                     /locus_tag="SLE65_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449306.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7237 a         3991 c         4790 g         6115 t
ORIGIN      
        1 tcgggggcaa ttttttgact atgctgatta ctcctgcgac agtggcactt gccatccctc
       61 tttataaaaa cttccgttta ctgaaagaga atttttatcc tgtaatggct gcgattttag
      121 caggaatagt cgcaaattgc ttggttagtg tagggttcgg ttacttcttc tctcttcata
      181 aagagatggt gatctcatta ctacctaaat ctgtaacgac ggctatttct gtcgatttat
      241 ctcatacgat gggcggggtg aatgccgtga cacttgctat tgttgtctct acaggtattt
      301 ttggttcgct gatcgccact catattttcc gcctattcaa gatcgaaagt ccagttgctc
      361 gcggtgtggc gttaggaagt acttctcatg ctattggtac agcaaaagca atcgagattg
      421 gtgaaataga aggaatcatt tccggacttg cgatatgcgt caacggaata ttgaccgttt
      481 tattgctacc gttattcttt cagccttttg ctggcttgtt ttgatgcgaa aaccactatt
      541 ttatgctaca ataaccaaaa cgttcgagca taaaaaagga gggaaagacg tgtatttgtc
      601 ttccgagtat cttaaacaat ttgataaaga tctatattat aagattctcc tcctagaaag
      661 ttttgaggat caagcttggc ataccgctgc acaattagcg caagttgttc agctggatgc
      721 ccgcagcgtg tcgaaatacc tgaacgagct gtctaaaaac tatcagcagt ttagcggtaa
      781 gacacaccct ttgtttacaa aaaatcaccg ttctggttat aacttttatg atacgctcga
      841 ttcaattgaa catgagcgtt ttttgatcta tctcgtgcaa agtacgctga aattccagtt
      901 gctgcacgac attttttttg aagaattcca tacaatgtac caatttgcgc aaaagcatta
      961 cattagtgaa tctactgctc atcgaaaaat caatgaatgg aaacagcaac tgcaaactta
     1021 cggaattcgg ctgcaacgag gtacatatat cgctcaaggc gaagaagaaa tcattcgact
     1081 ttacttgcat atgacattct ggcagttgtt tcgagggaaa atctggccat ttgaaacgat
     1141 ttctcaaatg gacgtaaaga atatggcaga acatatcatg gcttttttta atgttcgtct
     1201 gaacgagatc aaaaaaagac gattggaata tatgctaggt gccttttttt taagaaaatc
     1261 acagaagcat tatgttgtat tgaatgagaa aaaaagacgg ctgatttctg acaatctgtt
     1321 gttccagcga ttttgccagg tcatggagcc ggtatttcct aattattttc aagtagaaga
     1381 cgagttaggc gcattatttc ttgtactgat gactcgtgaa gaatattata gtgatcctaa
     1441 gatacggaag aaaatttttg attttcatca acaagcaaaa acaccgccct ttacagccct
     1501 ttcagaagca aaagccgctc tttctcttta tcaggaagag caggggctgc cagcagaaaa
     1561 tctaaccttc gaggcagaaa actatttatt cagcagtcat tttttcgcct atctttttcc
     1621 taatgcgaaa gaaacgattg atggcaatag tagtgatttt attaatcatt tagttattga
     1681 aaacaaggaa ttgaaacaat ggctcgtaca tttttttgaa agtagacaca aacatcccaa
     1741 tcatctggca tttaaaaatc atgcgttttt gatggggcgg tatctgactg tgtttaaaac
     1801 attaggagcc tttactccac agcttccaaa gatcacgatc cttttaatga cagatttccc
     1861 attatttgaa gagcaactgt tagaggaggg attacggaca tttttccgta atgagtatca
     1921 gctgattttt ctgccaacag attatcgggg gagagaagtt gatcttctga tttcgacaag
     1981 taaagtccac cgcaaaccat gggcggatct tgactatttt attgtgactg aagaactaaa
     2041 attaattgat tacatccaac tatctcaaaa atttgaaatg attcaaaaac aaaaactatt
     2101 aaaacaataa caaagaagga gaaaaaagat gacatttgaa gaaattttac cagaattgaa
     2161 aaaaggtgca aagattattc gtaaaggatg gagtggattt gaactttatg ttgttctcgt
     2221 atccgatgat gaatttgatg gctgtccggt gacgccgtac ttattgatca aaacaagtga
     2281 cgaaggtttt tccagcttcg ctcctacagt ttgtgatatt ttagcagatg attgggcgat
     2341 cgtagaatga aaaaccagta tccagatcta gctaaacagg ttgtatttat cacaggagct
     2401 gcttctggaa ttggtgctgc gcaagcccga gcgtttcttg aacaagatgc ttttgtattt
     2461 ggattagatc aaaagttcgg taaaatggaa gaaatttctt tgcgatttcc tgaaactttt
     2521 gcctacgcac taggtgatgt tcgacaaatg aaagaactcc aacaagcggt atcgaaatgc
     2581 caaaatcatt ttggtgaagt tacgatttta ctgaatacag cggggatatt ggatgcctac
     2641 aaacccttga tggaaactga cgaatcgctg tgggatctga tttatgagac gaatgtgaaa
     2701 agcatgtatc agctgacaaa aatcatcctt cctgatatga tccgccaaaa aagcggaacg
     2761 atcatcaata tggcttcgat tgctggcttg attgctggtg gaggtgggat cgcttataca
     2821 agcgcgaaac atgcgattgt cggatttacc aaacaactcg ctctggatta cgcaggacag
     2881 ggtatccgag taaaaggaat tgctccagga gccatccaaa caccaatgaa tgcggctgat
     2941 tttgaaggga aaggtgagat ggcagagtgg gtggcaaatg aaacaccagt caagcgatgg
     3001 gcacagccgg aagaagtagc tgagctgacg ttatttcttg cctctcctca agcaagctac
     3061 atacaaggaa cgatcatccc aatcgacggc ggatggttgt taaaataacc ttgtgttttt
     3121 ttcaagcttc tgtatgataa aactaaagag agaaacaacg gttgatgata aaaaaagtcg
     3181 atgactgttc ccgacattcg atgccgaaca gccagttcaa aaaattcttt ttaataatcg
     3241 ttaatattcg aaactaagcg gcttttcacg acctcttgat ataaacgata ttcaaaagct
     3301 tgcaactgcg gtaacaagtc cagccaaatg aaaaatataa ggagctattt ttatttgacc
     3361 attcttatta cttgttgcag ggcagctttt tcactacctt ctgcgacact tcagttggaa
     3421 ttttcttccc atcctttggt cgcggtcatt accaagataa aattatcttg caaaggagaa
     3481 atagaacatg gaaaaaaata atacccgttc agccaaacgc tggacaacga cagatgtgac
     3541 tcggatggcg ctagtcactg gtttatatgt ggcagtgacg ctggttttgt ctgtctttag
     3601 ctttggagtg attcagattc gtctctcgga gatgttcaac tatctgtcct tgtataacaa
     3661 aagatacatc gtcgcggtaa cagcgggagt agctttggct aatattgctt ctcctcttgg
     3721 actgatagat gttgcagtag gaagcgtcag cacgctgctt gtattgctta tcaactataa
     3781 aatcactagt cgcatcaaaa acatgaaaat caaaatggcc gtgacagcat gcgtatttgc
     3841 tttttccatg tttacagtag ctggtcagct aacgatttta tatcaactac cttttttctt
     3901 gaattggtgg gtgattgctt taggagaatt ggcatcaatg attgtcggtg ggataattat
     3961 ttattggatc ggtaaaaaag tggatttgtc aaaataaaga tctgtttaat ttaaaatagg
     4021 gcagcatgga agagactgaa tgttgagtct tcttccatgc tgcttttttg attaatttgt
     4081 atgaagaaat cgatttagcc gttttttcat caagataccg atataagctg ctccagttgc
     4141 cttgattgct tccggcagta aaaacggcag tagtccactg gcaaatgcag ttgtaaaagt
     4201 aagatcacca cttattttca gccagatcgt tccgcagatc aatgcagcaa gagagcccat
     4261 tagattggca aagattgcat ataagtaatg agcatccgtt ctttcgatca tccaaccagt
     4321 tatccacgtt tgtaagagaa atccaatcaa atatccgcca gttggcccaa ataaaacagc
     4381 tatacctcca gtcatccctg aaaatacagg aagaccaatc aagccaagta aaagataaac
     4441 tccaacagat atcaatccta gttttcttcc gagaaaagtt gctgttaatc caatagcaaa
     4501 tgtttgccct gtcaaaggaa ccaaaccaaa aggaatggtc atctgagaaa ggacagaaat
     4561 aatcgcggca aattccgcag caagtatcaa ttctttcaat gttcggttca taacgccctc
     4621 ttttcgttaa cttaatattt ttatttggtt aacgaaattg taaaacaaag tgattacttt
     4681 gtaaatagaa aatataaaaa aagaccagct atccaataga tagcggtctt tttcaagaaa
     4741 gcttttgaaa ttataagctt tggttgtagt attcaacgac aagagcttcg tcgatttctg
     4801 gatatagttc gtcacgttct ggtaaacgag tcaatgaacc ttccaatttt tcagcgtcaa
     4861 agcttacgaa tgctgggcgt ccaacagttg cttctacagc ttcttttact gttacgatgt
     4921 tttgtgattt ttcacgaact gagatcactt gacccacttc tacgtggtat gaagggatat
     4981 caacgcgttt gccatcaact aaaatgtgac catggttaac taattgacgt gcttgacgac
     5041 gagtcgttgc aagtcctaaa cggtaaacaa cattgtctaa acgttgttct agtaagatca
     5101 tgaagttaac accatgttta ccttctttga ttttgctagc ttttacgaac aagttacgga
     5161 attgacgttc gttcattccg tacatgtgac gaagtttttg tttttcagtt aattgcatgc
     5221 cgtattctga ttgtttgcca cggctattag gtccatgttg acctggtgcg taagggcgac
     5281 gtgctaattc ttttcctgtg cctgacaatg agatgcctaa gcgacgagaa attttccatg
     5341 atggtcctgt ataacgagac attaaaattt cctccaatga atataagttt ttggagtaaa
     5401 ataatccgtt gaaaaattca taatcatata gtttgttctt caatcttcac ctttgcagcc
     5461 gcggttacac aatcgaaccc gagacggggc aacaaactag ggatgagtta ttatttttct
     5521 gctgcattat tttacacaaa ttacagtata tgatagatca tccacgaatg tcaagataat
     5581 tagtacataa aaacgcttta caaacctagg ctgtctttat aaaatgagag ggtatgtgca
     5641 aatggaaaaa agcgaaggaa gtttaaggag aaaatcaatg aatccggtat caccattatt
     5701 tgagaaaatc gatgcttcaa ttgaaaagaa ggcgaatctt tttgaaaaca gcttttcacg
     5761 ttacgctgtt cgagcggttc tcgcctgttt gtttttgact ttaggaacgg ctgtggcatt
     5821 tgcgatcgcg atgaaggggg aagatatcgc gcatggtcta ggaaagattt tatacgcatt
     5881 tatgttcagc tggggtctgg tcatgattct atacatgaac gccgaattag gaacatcgaa
     5941 tatgctttat atgaccgtgg gtgtttttcg gcagagactt gctttaagta aggcagccaa
     6001 gattctattt gcctgtattt ttttcaatat gattggcggt atattatgtg gatttctaat
     6061 ttctatgact acgccatttc aagatttaac gttggacaac tttatgttag aatcaatagc
     6121 agtaaaacta gcaaaacctt cagcaacgat tttggtggaa gggatgtttg cgaatatcgt
     6181 tgtcaatacc gctgtactga tcagcatgcg gatgaaagag gatgtcggaa aagtgatcac
     6241 agtcgtattc atcattttca tttttgcttt tttaggatat gaacacgtga tagcgaattt
     6301 tcctgccttt acgcttactt actttgcttc tcacggacag atggatggaa tgacagtcag
     6361 caatgtgtta cataatttgt tttttgcttt ggcaggaaat tatattggtg gcggtttagt
     6421 aatgggactg ggatatgctt ggctgaatca gtcaaaatca tcctatgtgg actaaaaagt
     6481 cgttcattaa aggggaagtg ccatggaagt tttagttttt ccaaaaaatg aggaaaaagc
     6541 gttacaaatg gaaaagtaca tgaaaaatct tttttccttt gctggagtac ctaagccgga
     6601 acgcgctctt ttacaacaac cgttactgga tgagagcaaa aatttatcta tttctgaagt
     6661 tttagctttt gttcattatt attatgaaca aatcgaaaga gagtatcagt atgtagcgat
     6721 cgatttagtc cagaaaaaca tcaaacggct tacatttgaa gacttagtcg tattgttgcc
     6781 actagttcag aaaaaagaat ggtgggacag catcgactct tggagaaaag tatacagcac
     6841 atggtgtaaa gcctacccag agcagcgtga agaagtcttt caattgtttg aaaaaaagga
     6901 agatttttgg ctacgtcgaa tagcaatcac gttgcaatta ggttataaac agcaaacaga
     6961 cacaggacta ttgatccgag caatagacga agatcgtcaa acaaaggaat tctttatcca
     7021 aaaagcaatt ggttgggcat tacgcgatta tagtaagacc gatgccgatt gggtaaaaag
     7081 acagctgaca acagatttga gtaagttagc tgttcgagag gcaagtaagt atttataaga
     7141 aagcgagacg acaagagatg agacgcaaat tatttgcttt tgatattgat ggaacgttgt
     7201 tagattcaaa caaacaagct ttagatagca caagagaagc attggaaaaa ttacgcaaag
     7261 ccggtcatct ggtcacgatt gctacagggc ggagccgatt tcatgcgcaa gagatcattc
     7321 gcgatcttga ttttacgaac tacattttat gtaatggagc ggccggtttt ttagaccatg
     7381 aacaagtata taagaattta ctagatcgcg accagttgga tgcgttcgtt caagaagcgc
     7441 atcatgagca gatcgataca gcttttgtca gcttagacaa tatcaagcgt tcttcttcca
     7501 atgatgtaac ggtgatggaa gaagcgatgc attctttcgg tgctgtcttg cctgaattag
     7561 atcagttttt tgcagaggaa caagaaatat accaagcgtt agcatttttc gatcaaacat
     7621 atgatgggaa gttctcttca tatgataaaa ttcgatttgt ccgctggcat gagaacagtg
     7681 tagatgtcgt acctaaaaat ggttctaaag cagcgacaat tctgcactta gcagaacaag
     7741 taggcatccc tcatgaagac atcatcagct ttggcgatgg acaaaacgac cgtgaaatgt
     7801 tgcgcatgtc aggaattggg atagctatgg ggaatgctgt gccagaagta caagcagaag
     7861 ctaagatggt cactgataca aacgatcagg atggaatttg gaaggcattg aaagagttaa
     7921 gcgtgattta aaagaggttg tgaaaaagct gttctgcatc aagtaataag cccagccaaa
     7981 caaaaatagc tcctcctatt tttcgttttt ctgggcttat taccgcagat gcaagctttc
     8041 gaacaccgtt taaggaagag gtcgtgacag aagtggtcag tttcaagaaa taagaaggga
     8101 tttacgaaaa ttgcttctca aatttttgta aaattacggc ttatttctga agaagtagat
     8161 gaaacaacgt ttattcggga aatgggactg tgacaagatg tttgtcatag tcccattttt
     8221 ttattttatt tttcaaaact aagaaatacc aggaaagagt tccttttgtt tgaccttttc
     8281 tttcttattg aaaacaacta taatatagag tgatgttaaa agagaagagg aatttagtgt
     8341 gcgggtattg tttattggtg atgtagtagg ttcaatggga cgagagatga ttactgaata
     8401 tcttcctaga ttgaagaaga agtaccgtcc gcaagtaacg attgtaaatg gtgagaatgc
     8461 cgcttctgga cgtggaatca cagaaaaaat ctataaaaaa tttttgcaag acggcgtaga
     8521 tgtcgtgacg atggggaatc atacgtggga caaccgcgga atctttgagt ttgtaaatga
     8581 agctaaaaag atggttcgtc cggcaaattt tccggaaggg acgcctggac aagggatggt
     8641 ctttgtcaaa gtgaaccaag tcgaactggc agtgatcaac atgcaggctc gttcttttat
     8701 ggtggacttg gatgatcctt ttcgtaaaat gaatgagctg gtagaagaag ccagaaaacg
     8761 tacgccgatc atttttgtag attttcatgg agaaacaaca agtgaaaaac aagcaatggg
     8821 ctggttttta gatgggaaag tttcagcagt ggtcggtaca catacacacg ttcagacaaa
     8881 tgatgcgcga attttgccaa gaggaacagc gtatctgaca gacgttggga tgacaggtcc
     8941 ctatgatggt attttgggta tgcgcagaga acctgtaatc gaaaagtttc tgactgcatt
     9001 accaaaacgt tttgaagttg tggaacaagg ccgatcgatt ttaagcggct gtatcttgga
     9061 attggatgat acgacaggtc atgcaaaaga aatccagctg attcagatca acgatgatcg
     9121 accgttcatg gagtagaaag agaggcagtt ttttgcagca ggagccggaa attcaaaaag
     9181 aagtaaggaa actgacaaaa cttttaagag agaatgaaac gatcattcgc tacaaagaac
     9241 ttgaagaaaa gatccagcaa aaccagtatt tagctgagtt gagagaaaaa atcaaacaag
     9301 cgcaaaaaga tgctgttcat tttgcccact atgacaaacc agcagcagaa aaagaagcaa
     9361 tcaaacaagc ggatcaattc atgcaagaat ttgatcagca tccgcttgtt gtagcttata
     9421 gaaaacagct gttggaagca gatgatctgc ttcatcattt aacaactatg atacaagaag
     9481 aaatcaatgg acaaatagag gaggaaaaac atgcctcaaa aaactaaaaa tactcctatg
     9541 atggaacaat atctaagcat caaggcccaa taccaagatg cttttttgtt ctatcgttta
     9601 ggagactttt atgaactatt ttacgaagat gcgatcaaag cgtcacagct tttggaatta
     9661 acgttgacga gcagaaatcg aaatgcagaa gaacctattc ctatgtgcgg tgtacctcac
     9721 catgcagcac aaggatatat cgatgccttg attgaaaaag gctataaagt agcgatttgc
     9781 gagcaggtag aagatccaaa gacgactaaa gggatggtca agcgcgaagt gatccagcta
     9841 gtcactcctg gtacagtcat ggacagcaaa ggattgtcgg caaaagacaa caatttttta
     9901 acagctgtag ttagtcaagg aaatgaattt ggctttgctt atgccgattt aagtacggga
     9961 gaattgaaga cggctcggtt gcatgatgaa gaagctgttt taaatgaagc ctctgcattg
    10021 cagacaaaag aactcgtatt aggcagtgag atcactgata cccttcgtga acagctaagc
    10081 gggcgtttag ggctagtctt ttctcaacaa aatgagatgg aagaaaacgc ggaatttagc
    10141 tttttgacaa gcgaactagt cgatccgctg gaaaaagaag caaccggcaa actattgact
    10201 tatttatcgg tgacacaaaa gcggagttta gctcatatcc aaaaagcagt agaataccaa
    10261 ccagatcatt ttttgaaaat ggattattat tcaaaattca acctagaatt aagccaatct
    10321 attcggactg ggaaaaagca cggcactctt ctatggttgt tagatgaaac aaaaacagca
    10381 atgggtggcc gtttactaaa acaatggcta gaccgtccgc ttatccaggc aaaacaaatt
    10441 aaagcaagac aagaaatggt cgcttctttg ctagacagct attttgaacg tatcgatttg
    10501 cagtcagcat taacgaaagt ctatgatctg gaacgcctag caggtcgagt agctttcggt
    10561 aatgtcaatg ggcgagactt gatccagctg aaaacttctt tagaacaagt gccaatgatc
    10621 agagggttga ttgaaggaat cgatcaaggt caatggcaaa gtctgctttc agaaatgcag
    10681 ccgatggacc atctcgtcca attgatcgac caagctatcc aagatgatcc gccgttacaa
    10741 ataacggaag gaaacatcat caaagatgga ttcaatgagc agctcgatat gtaccgttct
    10801 gctatgagaa acggaaagaa atggttggca gaacttgaag caaaagagcg tcaagaaaca
    10861 ggaatcaaga acttaaaaat cggatttaac cgcgttttcg gttattatat agaaattaca
    10921 aaagcaaatc ttggaaatgc agaactggag aagtatgaac gaaaacaaac tttagcaaat
    10981 gcagagcgtt tcatcacacc agaactaaaa gaattggaga cacaaatcct cgaagcagaa
    11041 gaaaaatctg ttgatttaga atatcagttg tttttagctg tgagagaaga agtcaaaaag
    11101 gctatccagc cgctacaagt acttgcaaaa gcaatcagtg cagtagatgt gctacaaagt
    11161 tttgcaacga tcagcgaacg ctatcagtat gttcggccag aacttgtcag tgacaagcat
    11221 cagcttctga tcaaagacgg acgacatcct gtagtagaaa aagtattagg acatcaggaa
    11281 tatatcccta acagcgtaga aatggcagaa gacgaaatga tcttgctgat tacaggaccg
    11341 aatatgtctg gtaaaagtac gtatatgcga cagttggcat taactgttct gatggcgcaa
    11401 atgggctgtt tcgttccggc aaaacaagca gttttaccta tttttgatcg gatttttacc
    11461 cgaattggtg caagtgacga cttaattgct ggacaaagta cttttatggt agagatgatg
    11521 gaagccaatc aagccctgcg ttatgctacg ccaaacagtt tgattttgtt tgacgaacta
    11581 gggcgaggaa cagcaaccta tgacggaatg gcgttggccc aagcaatcat cgaatatatc
    11641 catcgtcatg tacaagcaaa aacactcttt tctactcatt atcatgaact gacggtactt
    11701 gagaaagaac ttccgcagct taaaaatgtc catgttggag ccgttgaaaa agacggagaa
    11761 gttgtcttct tgcataaaat gatggatgga cctgcggata aaagctacgg catacatgtg
    11821 gcaaagatcg caggattgcc ttccaatcta ctagaacgag cagcagatat cctgcatacg
    11881 ctagaaaatg gcgataacgg acaccatact gttccagctg aagtagaaga gaaaactaaa
    11941 acagccaaac aggagcaaat aaaaccacct gcagaaaaag taaatcaaga ccatatacaa
    12001 gaccgtgtaa aagaagaaaa ccaacagctt tctttattca gtgaattatc cgaaaatgaa
    12061 acagaagtca ttgaatcact gaagcaaata aatttactag aaatgacgcc aatggatgca
    12121 ctaaacacat tatatgaatt acaaaaacaa ctgtaggaag aaggcggata tcgatggcca
    12181 aaatccaaga attatctgaa cgtttagcta atcagatcgc tgcgggagaa gtagtggagc
    12241 gaccagcttc cgttgtgaaa gaattagtgg aaaatgcaat tgacgccggc agtactcaga
    12301 ttgatatctt agttgaagaa gcgggactgc ggacgatcca agtgattgat aacggagaag
    12361 gcattttggc agacgacgta gagaatgcct tcaagcggca tgcgacaagt aagatccata
    12421 atcgcgacga tctttttcgc atacgaacgc tgggctttcg aggggaagct ttgccaagta
    12481 ttgcctctgt ttctgaaatg actctggaaa cggcgaatca ggaagaaaaa caaggcacct
    12541 atctgtcgct gaaaggcgga gaagttattg agcatcgacc agcaccactg cgtcaaggaa
    12601 cgaagattac cgtcagcaat ctgtttttca atacgccagc ccgcttgaaa tacgtgaaaa
    12661 cactgcacac agaattagcg aacatcgggg acatcgtcaa tcgactggca ttgagtcatc
    12721 catcgattgc ttttcgttta gtacatgatg gaaacaaaat gctggcaact gctggaaatg
    12781 gcgatctgaa acaaacaatt gcgggaatct acggattatc taccgcaaaa aaaatgctga
    12841 aaatcgaagg aaaagatcta gattttgagt tatttggcta tgtttcattg cctgaggtga
    12901 ctcgtgccag taggaattac ttatcgacga tcatcaatgg acgttttatc aagaactttt
    12961 ccttgaataa agcaatcgtt gcaggttatg ggtcaaaatt aatggtcggt cgtttcccta
    13021 ttgctgtatt ggaaatcaaa atggacccgc ttttagtaga tgtaaatgtt catccgacga
    13081 agcaggaagt ccggctgtcg aaggaaaaag aactaacaga gctaattagt aacgccattc
    13141 aaaaagcatt gtctcaagaa aatctgattc caagtgcagc ggataatcta cggtttaaga
    13201 aaaaagtacc tgatcagcct aaaacagaac aaatcgaaat cgatttgtcc tacgcttttg
    13261 aagaagaaaa acctaaaaag ccaagtagtt tgaattttga tcgagagaca ggtacctttt
    13321 tcgtagaaga actaaagaac acatttgttg acagaattgt tgataagtct gtggaaaatg
    13381 ttgaaaacta ttctggtttt tctgaagaaa acaccactta tccagaaaaa acagcgaaaa
    13441 cggtggataa gtttggtgaa aatgttgata actttgtaga aaaaacagtg gaaaaatctg
    13501 aaaagaaaga atttcccatt gtggataaca tggagaaaac aaatgaagaa caagcagata
    13561 aatccgtaga agaggatgaa aagatttacg aggaagaatt gacactccat cctgaatttg
    13621 atttcactca aggaaacgac aaaacattag aacaagccat caagaaatta gaaacggaaa
    13681 aaccagtaca acgttttcct cagttggaat attttggaca gatgcacgga acgtatcttt
    13741 ttgcccaaag tagcgatggg ttgtacatca ttgatcagca tgctgcccaa gagcgcatta
    13801 agtatgaata tttccgggaa aaaattgggg aagtatctga tgatctgcaa gaattgcttg
    13861 ttccatttgt gttagactat ccaaacagtg atgctttgaa attaaaagag caaaaacact
    13921 tgctagaaga tgcagggatt tatttagaag aatttggtca aaacagcttt attgtacggg
    13981 cccatcctac ttggtatccc aatggagaag aagaatcgat tattcgggag atgatcgata
    14041 tgctgctgac aactggaagt gtgagtgtaa aaaaattccg tgaagcaaca gcaatcatga
    14101 tgagttgcaa acgatcgatt aaagccaacc attatttgaa tgaagcacaa gcacgtgtgc
    14161 tgctgaagga tctggcacga tgcgaaaatc ctttcaattg tccccatggc cgtccagtat
    14221 tgattcactt taccaattcg gatatggaaa ggatgttcaa acgaatccaa gacccgcatt
    14281 aagtcaaaga gaagagggaa aacatgaaga ttgtattagc atcccaatca ccaagaagaa
    14341 aagagttatt ggctcatatc gtttcagaat tcgagattga acctgctgat atcgatgaaa
    14401 cgccatttcc agacgaacag cccgtcgatt atgttcgtag aatggctgaa gaaaaagcac
    14461 gaactgtctg ggaacaagat gaaaaagaag accatttagt gattgccagt gacacgactg
    14521 ttgttctcaa tcaagagatc atgggtaaac cagaagatct ggctgaggct gaattcatgc
    14581 tgaaaaaact aagcggggaa acacatactg tatatacagc tgttgtttta aaaacaaagg
    14641 aacgagaaga acggatacta gcagaagcac atgtcacttt ttatcctttg acagacgaag
    14701 agatcaaacg ctacttggag acgggggatt atgcggataa ggcaggggca tacggcatcc
    14761 aaaatgctgc gagtgtattc gtcaaagaaa tttctggaga ttattacagt atcgtaggat
    14821 ttccgattgg tgctgtcaat caggcactga aaacattcat ttaaacaaaa aagcggacta
    14881 tctgattttc gattgaaaat ccatgatagc ccgttttttt tattgaaaag attacttatc
    14941 tactctgact aagattttac ttcagcttta ccgactgctt cgcccgggcg aacaagtcct
    15001 gattggtcaa gagaaagtcc tgcaactttt tcattattgg tcaaagcaac aataatgtca
    15061 gttttcttgc cagcttgttc tatttctggc aaatccattt cagcaatcag ggtctctggt
    15121 gtgacaaggt atccttcttt cacgaataca ttgaaaggaa caccctttag ttcaacagta
    15181 tctaatccca tgtgaacaag tacttccagc ccctcattag aaagaatacc aatggcatgt
    15241 tttgtttcaa agacactcgt cactttaccg tttactggtg catagacttt gccgtttgac
    15301 ggttcgacag cataaccgtc acccatcatt ttttgtgaga aaactgggtc atttacttca
    15361 gttatttcct tgatggtccc tgcagcgact gcgaataatg tttcttttgt tgcaactgcc
    15421 gtaccagttg ctgaaacagg ttcgaaagac tgtggcgttg ctgttgcgcc atttgctgtt
    15481 tgaagttgta catcagcagc attttcagga acagcaggat caatcttatt caaaattccc
    15541 tgacgtctaa agatgatcgt caagccaaat ggaatgatga cagcaatgat cattgcgatg
    15601 atgaaaggta cccatgtttc tgcttggata gctagtattc ctggcaaacc gcctactccg
    15661 atcgcgttag ctcgaacacc catcaagtta gcaaacatgc cagctaatcc agagccgacc
    15721 attgcagcga cgaaaggata gacgtatttc aaattgattc cgaacatagc aggttcagtt
    15781 acgcctaagt aacaagaaat cattgctgga atcgagattt gttcttcttt tttattccca
    15841 cgatgtaaga agatgatggc taagactgca gagccttggg cgatatttga taaagcaatc
    15901 atcggccata aattcgttga tccgaaatct gcaatcagct gcatatcgat ggcattggtc
    15961 atatggtgga gaccagtaat cactaaagga gcatacagga atccgaatac ggcactaaac
    16021 aaccagctga tagaagacgt caatccagta tttacgatat ttgagatcca gcttccgact
    16081 gtccagccga taggacctaa aataacgtgt gcagctaaaa cagttggtaa caatgaaaac
    16141 aatggaacaa aaatcatcga gatcgactga gggatatatt tgcggaagaa gatttctaga
    16201 tacgctaaca taaaccctgc cagcatggct ggaataactt gcgcttgata accaatcatc
    16261 tggacttgag caaaaccaaa atcccaaaat ggaatatctg ctgcggctgt ggaagctaca
    16321 ctataagcat ttaataattg cggagaaact aacgtaattc ctaaaacgat tcctaatatt
    16381 tgtgtagtac ccatcttttt tgcaatactc caagtgatac ctactggaag aaaatggaaa
    16441 attgcttcac ccggtaacca caaaaaggca ttgacaccat tccaaaactt cgagtgttca
    16501 acgattgttc caccaagact ttcaaactgg ataccttcaa gtacatttct gaatccaagg
    16561 atcaatccac cgacaatgat tgcaggaatc agtggtgtaa agatttctgc taaaacggca
    16621 atagcacgtt gaacgggatg aaggttttgt tttgcagctg cttttccttg ttctttggaa
    16681 accccttcaa ctccagatac tgcaacgaag tcgttataaa aagtagaaac atcgtttcct
    16741 atgatgactt ggaactgtcc tgcattcgtg aacatccctt ttacgctagg tatatcttcg
    16801 atcgcttttt cgtccgcttt tcctggatca ttcaggacaa aacgcatacg agtcgcacaa
    16861 tgactaactg cagcaatatt ttcttttccg ccgatatcat gtaacagctt ctcggcatct
    16921 gcttgatatt ttgccatatc aataaacccc tttctcttaa cttgtctatg caagttgttt
    16981 cttcatttac tatacttttt ttcggagaga attgcaagcg ttttattaaa aagtacgaga
    17041 gaaaatgata tcgttttaaa aagcttaaaa taagcttttc ttaaaaatag gaacattgaa
    17101 atacaaaaag agctgtagta tagtgaagaa atgatggaag aacgagtgag ggaaaaaaca
    17161 tgaataagtt caatgaaatt tttttagatt tggaacagaa aattttagcg aaagaatatc
    17221 ctccgcattc gcttttaccc agtgagaacc aattgatcaa aatttatggt gtttcacgag
    17281 aaacaattag aaaagcgctg aatcttttga ctacggaagg ttatattcaa aaaaaacaag
    17341 gaaaaggttc gatcgtactg gatcggaatc gcttcgactt tcctatttct ggattgacta
    17401 gctataaaga gctacaggag acccaacgta ttccaagtga aacgatcatc catacgttag
    17461 aagaaacaga agtgacaaaa gcattgaacg agatcactgg ctgggagatc ggtgcgcctg
    17521 tttggcattt gatacgcgaa agaaaaatca atggcgaagt agttatatta gacaccgatt
    17581 atctattaaa ggaaatcgtt cctattttaa ctccagcaca agcacaagga tcgatctatg
    17641 aatattttga aaatgagctt tctttgacga ttgcttacgc gcaaaaggag atcacagtag
    17701 aagaagtaac ggaaatcatg aaaacagcga tggatcttca cgatgacact tatgcagtag
    17761 tagtcagaag cctcgttcat ctggaagata cccgctgttt cgagtattct gagtcggttc
    17821 accgattaga taaattccgt ttcgttgagt ttgcccgacg ccgaaaagtg taaatagttc
    17881 aaaagaaagc aaattgttgg catctgtcca ctttggcgct atgataggat cacaaagggg
    17941 gcatttttaa tggataaacc aataagacca gaaaaagaag aactgaaaga aaagttatca
    18001 cccatggctt atgcagtcac acaagaaaat gcaacagaac gaccatttag cgggaaatat
    18061 gatgattttt acgaaaaggg gatctatgta gatatcgtca gcggtgaacc gttattcagc
    18121 tctgcagaaa aatatgatgc aggttgtggc tggccatcat tcagcaaacc aataacgaaa
    18181 agacaagtgc gcgaaaaagc cgatttttct catggcatgc atcgaataga agttcgaagc
    18241 aaagaagcag attctcatct cggacatgtg tttaccgatg gaccagtaga tcaaggtggt
    18301 ctacgttact gcatcaattc tgcctcactg aaattcattc catatgaaaa gatggatgaa
    18361 ttaggttatg gggaattcaa atcacttgta gaataatgga aatacacaaa gagcggtaca
    18421 atacggggat ttactcgatc gtccgctctt tttttattca agcgattgct atttgaaaga
    18481 aacgctccct agactccttt tttcacaagg tgaaatgtgc tacaataaag ggaacgtatg
    18541 tgtgcaaaag aaagaggact agaatatgta tgaatatctg acaggtgtgg ttacctttat
    18601 caacccctat tacatagtag tagaaaccaa tggtatcggc taccagatcg cactaggaaa
    18661 tccttaccgc tacagtagca aactaaatca aaaaataaaa atttatgtcc atcaggtaat
    18721 acgtgaagat gcgcatcttc tgtatggatt tgattcgcta gaagaaaagc aactgttttt
    18781 gcgattagta agtgtttcag gaatcggtcc gaaaagtgcc cttgcaatca tggcaagcga
    18841 agaccactcc ggtttgattc aagcagtaga atccagtgat gtcacttatt tgacgaaatt
    18901 tccaggagta gggaaaaaga cagcacaaca aatgatcttg gatctaaaag gaaaattcgg
    18961 tgagctgagt atcgatacac cttttagtct atttgatgaa gcaaacacaa aagacgctac
    19021 agctctatct gaagcaatgg aagctctctc ggctcttggt tacagtgatc gagaaatcaa
    19081 acgtgtagaa aaacaattaa aagaagtaga taatcagaca acggatgagt atctacgcca
    19141 agcactcaag ctaatgatga aaaaataagg aggagaccaa atgacagatg aatacttgtt
    19201 atcaccagaa tctggcgaaa atgaactgag tttggaaaaa tctcttcgac cacagctgct
    19261 ttctcaatat atcggacaga gaaaagtcaa acaagaactt cagatttaca tcgaagctgc
    19321 cagaaatcgg gaagaacctt tagatcatgt tctgttgtac gggcctcctg gattaggaaa
    19381 aacgacgatg gccatggtca ttgctaatga gatgaccgta aatattcgta cgacgagtgg
    19441 ccctgctatc gaacgtccgg gtgacttagt agcaatcttg aatgaactgg aagcagggga
    19501 tgtcctgttt atcgatgaga tccatcgatt acctagagtg gtagaagaga tgctttattc
    19561 agctatggaa gatttctatg tagatatcat ggtaggacaa gggccaaccg cacatccggt
    19621 tcatttccct cttcctccct ttactttgat tggcgcgacg acacgggcag gtatgctttc
    19681 tgcaccttta cgagatcgat ttggcatcat ttctcatatg gaatattatg acgaacagga
    19741 tctgcaggag atcgttttac gttcttcgga tatttttcaa acagagatca ttgaagaagg
    19801 ggcattggaa attgctcgcc gatcacgagg aacgcctaga atcgctaatc gcttgctcaa
    19861 acgggttcgt gattttgcgc aagtccaagg agacgggaaa atcgatcgtc ctatagcgga
    19921 tcaggcactt actttgctac aggtcgatca ggctggattg gattatgttg accagaaatt
    19981 gttgcgaaca atgatcgagt tatatggcgg cggaccagta gggttaagta cgctttcagt
    20041 aaacatagga gaagagcgtg agacggtaga agatatgtat gaaccgtatc tgatccaaaa
    20101 aggattttta aagcgtacac ctagagggcg aattgctact gcttatgcct atgaacattt
    20161 tggttacgac tatcatatat gatttttgct tttagattgg aggaaaatga atgagtgata
    20221 caacacgtac gaaacaattg atcaaaaacg tattgattga tttgtgccaa acgcaatctt
    20281 ttcgaaaaat cagcgtccaa aaaatcgcaa acgaagcaaa aatcaatcga caaacatttt
    20341 attatcattt tacagataaa tacgatttgc ttcgttgggt ctattgtgag gatgcattgc
    20401 attatttaga tccacaatgt ctttcacttg ataattggga agagcaagca ttgaaaatgc
    20461 tgaaagcaat tgctgagaag aaagaatttt atgcaaatac tgtgctttct gacccagaaa
    20521 ttttacaaaa agagttttct caactgatcc aaaaatcatt tatcaagatt tttgaacaaa
    20581 tggatgaaga aagacaactt tctgcaagag acaaactatt ttatgctcgt tttttttctt
    20641 acggttgcag tggtgtatta gtcaattgga tcacgaatga atatgaagaa acaccgatgg
    20701 aaatcgctat gcagcttttc cgtttagcca aggatacgga attatattct tatcgtcttt
    20761 atgcaaaaga agagttggaa gaacagtaat agaaaaattt tttgttggaa aagcaataat
    20821 cgctaaaagg agatggggaa atgacaaaaa ttttatttgt ttgtttggga aatatttgcc
    20881 gttcaccgat ggcagaaggc ttgctgagaa aacgaatagc attagaagga agggaagcag
    20941 aattttttgt ggattctgct gctacaagca cgtatgaagt tggaaagaca ccgcaccctg
    21001 gaacgaaaaa aatattaaac caagaaaaag tagatatgac gaatatggtt gctcggcaaa
    21061 tcacacccca cgattttgaa acttttgatt ggatcattgg catggatcaa gaaaatgtag
    21121 aagaactgaa acgaagagca ccacgctcag cgcaggggaa aatccatttg tttttaagta
    21181 gcattcctgg aaaagaaaaa gaaaatgttc ccgacccata ctataccaat aactttgatg
    21241 agacatatca cttgatcaca gaaggcctga atcattggtg gaatatttgg attgatgaaa
    21301 ataaaataac aaacaatttg taaagttaac gctttctttt taaggcgatg ttagagcatt
    21361 tccttgtttt tttgtaaaat gttaggtaaa ataaaattaa ttaagtaaca ctttcttagc
    21421 taaaggagga gtgcattcga tgaacgaaga gacagtatcg ccaatgaaga agcttacgaa
    21481 gttagttact catacttcgt atcaactttt tgattctttt gtaaatgaca ctgaagaaca
    21541 tgctaagaat gtacgattgc aaggaaagtt tattcttgag ctgcaaaaag ctgctactga
    21601 acatagtcta gttatcttac aagtaagagc aaatcgtttg agtagcaagt atgaaacgat
    21661 ctcaggctgg gtggcgacaa aaacggtcga aaaagaccga gtgatgatcc gcctacaaaa
    21721 cgaagagcag cagatccgga tggttcctgt agaacaaatt gaaaaaataa caatcctttc
    21781 accagcaggg gaacaggaac ggttatcaaa ataatttata ccagatagaa aagcacgtat
    21841 gagcttgtac catcaatcat tactaatcaa aaataaccga atgctttaag ctgatatcag
    21901 taaaacggaa cgttttagga tgagtatcat agcatgacag cattcggttg attagttgaa
    21961 tcgattggat ggtacaagtt tttttgataa aaaaaggtcc tgctagccgg ggagctagca
    22021 ggataaggag ttaaaaatga aaaagtgttg ttagggttgt ttgttggtat gcttatataa
    22081 tagtcattag ttgtgaatat tttgtgacga aagttttcga aagttgttaa gtt
//
LOCUS       DARPZF010000043        21503 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.044, whole genome shotgun sequence.
ACCESSION   DARPZF010000043 DARPZF010000000
VERSION     DARPZF010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21503
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.044"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            5..403
                     /locus_tag="SLE65_002017"
     CDS             5..403
                     /locus_tag="SLE65_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEI8449307.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            387..1082
                     /locus_tag="SLE65_002018"
     CDS             387..1082
                     /locus_tag="SLE65_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEI8449308.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1666..2553)
                     /locus_tag="SLE65_002019"
     CDS             complement(1666..2553)
                     /locus_tag="SLE65_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HEI8449309.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2738..3577
                     /locus_tag="SLE65_002020"
     CDS             2738..3577
                     /locus_tag="SLE65_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEI8449310.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3773..4747
                     /gene="sgrA"
                     /locus_tag="SLE65_002021"
     CDS             3773..4747
                     /gene="sgrA"
                     /locus_tag="SLE65_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HEI8449311.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5045..5401
                     /locus_tag="SLE65_002022"
     CDS             5045..5401
                     /locus_tag="SLE65_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449312.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5404..6561
                     /locus_tag="SLE65_002023"
     CDS             5404..6561
                     /locus_tag="SLE65_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8449313.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6587..7027)
                     /locus_tag="SLE65_002024"
     CDS             complement(6587..7027)
                     /locus_tag="SLE65_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEI8449314.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7187..7693
                     /locus_tag="SLE65_002025"
     CDS             7187..7693
                     /locus_tag="SLE65_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEI8449315.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7861..9774
                     /locus_tag="SLE65_002026"
     CDS             7861..9774
                     /locus_tag="SLE65_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEI8449316.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9779..10780
                     /locus_tag="SLE65_002027"
     CDS             9779..10780
                     /locus_tag="SLE65_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEI8449317.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10982..11188)
                     /locus_tag="SLE65_002028"
     CDS             complement(10982..11188)
                     /locus_tag="SLE65_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HEI8449318.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11834..12682)
                     /locus_tag="SLE65_002029"
     CDS             complement(11834..12682)
                     /locus_tag="SLE65_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEI8449319.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12681..13748
                     /gene="gnd"
                     /locus_tag="SLE65_002030"
     CDS             12681..13748
                     /gene="gnd"
                     /locus_tag="SLE65_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HEI8449320.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13750..14751
                     /locus_tag="SLE65_002031"
     CDS             13750..14751
                     /locus_tag="SLE65_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HEI8449321.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14748..15032
                     /locus_tag="SLE65_002032"
     CDS             14748..15032
                     /locus_tag="SLE65_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HEI8449322.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15065..15862
                     /locus_tag="SLE65_002033"
     CDS             15065..15862
                     /locus_tag="SLE65_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEI8449323.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     LYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15876..16709
                     /locus_tag="SLE65_002034"
     CDS             15876..16709
                     /locus_tag="SLE65_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8449324.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16727..17584
                     /locus_tag="SLE65_002035"
     CDS             16727..17584
                     /locus_tag="SLE65_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEI8449325.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17606..18115
                     /locus_tag="SLE65_002036"
     CDS             17606..18115
                     /locus_tag="SLE65_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8449326.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18152..18553
                     /locus_tag="SLE65_002037"
     CDS             18152..18553
                     /locus_tag="SLE65_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449327.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18665..19018
                     /locus_tag="SLE65_002038"
     CDS             18665..19018
                     /locus_tag="SLE65_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449328.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19052..19495
                     /locus_tag="SLE65_002039"
     CDS             19052..19495
                     /locus_tag="SLE65_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEI8449329.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19512..20597
                     /gene="uxuA"
                     /locus_tag="SLE65_002040"
     CDS             19512..20597
                     /gene="uxuA"
                     /locus_tag="SLE65_002040"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEI8449330.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20590..21303
                     /locus_tag="SLE65_002041"
     CDS             20590..21303
                     /locus_tag="SLE65_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEI8449331.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         7401 a         3301 c         4491 g         6310 t
ORIGIN      
        1 agagatgacg atctttgaaa cggttgtaac agatgttggt atagaagcag aagtattcag
       61 gaaagaaaaa ataatgattt tatttggaga tgaagcaccg gaaacattaa cagattattg
      121 ttataagatt gaattgaatc aggtaagaaa agaaataact tgtgatatga agctctgttt
      181 tgataaacaa atgtatgtaa tcacagcagt aggagatgtt gtccaaacta atttgaatga
      241 attaggacat atcacgataa aatttgatgg atctcatgag ccggaacttc caggaacaat
      301 gtatgtagaa gataaggaaa tgccgcattt aagaaagggg acaatcatta aaatcgatca
      361 agaggatcag aatgggggaa agctatatgg aaatcatgct tgatacagca aatacaaaaa
      421 gtatttattc ttgtcaacag tttttgaatt taacaggcgt aacaacaaat cctacaattc
      481 tgaaaaaaga aggagcgtca aacttcttct cgcatatgaa agaaatcaaa aaaataatcg
      541 gacagattcc tatccatatt cagacaatag gaagaacgga agaagaaatg atagaggatg
      601 ctcgagttat catagaagaa ctgggaaaag atacgtttat caaggtgccg gtgaatcaag
      661 caggccttca agcgatcaaa aagttgaaaa aagaaggtta tttgattacc ggtacagcta
      721 tttacacaga attacaaggg tatttagcta ttaataatgg agcagattat attgcacctt
      781 attataacag gatgcaaaat caaggcattg atgctatgaa agtgattgat tcgttgcgga
      841 ctgagatcga acgtacgcaa agaccaacaa aaatattagc agctagtttc aaaaattgtg
      901 aacaagtcac tacagccatt cgatctggag ctcatgcgat aacgttaggt aaagagctac
      961 tagatcaagt attagagatg ccctcgattg ataaagcagt gaggggcttc caagaagatt
     1021 gggtgcaaac tttccaagca gaaacgattg gtgaactaaa aaaggtcgct gattacttct
     1081 gaatcaattt ctccataaaa taaacgatag ccttctcgaa aactcgagga ggctatctga
     1141 cgattcaata ttcattaatt taaagtttgg gtgactatta cttatttctc atttaaacga
     1201 tgtattccct aacctctaat acatccttgt aactctgaag ttacgccagt tttgaataaa
     1261 tttcataaaa acaaatgaaa agtgtcgcat aaaaatatct ttcgtgtttc tctagtataa
     1321 cagaataaga ggaacaagtc cagaagggat atttttagtc ttttttaaaa taacttttca
     1381 gtcgagtttg agtttatgat agttgttttt gaagcgatac ggcaagtgaa aaaataggga
     1441 agcatgaaag aatctactta atggcgcatt gattcatgtg atagaaataa aaaacttttt
     1501 taaattatat cctcatgatt gtaacaaatc cagtgatttg ttttggtaca aataaaaaaa
     1561 ggccccgatg aagttgtggc aaaagtggtt tgcctcaaaa ataagaagga atttccaaaa
     1621 atcacttctc aaattttgcc acatccccaa ttgggtcaaa tttgtttatt tgaatatatt
     1681 ttttacataa ggatctttaa tagttacatt gtcttttttc atcactttac ggattgtttt
     1741 atccatgaat tccgtatcaa gagtttttgc ttcggtagca attttttcta gctcagattt
     1801 gtatttgtct ttattagaac ctttatcctg tttttttacc atttttacta gataatagct
     1861 ttgctgataa gtcgttggat ctgttacagg aatgatatca gaaacttccc cgttttttag
     1921 tttaaatgct gcttttttta cttcagtagg aatctctgga ttggttgaat caaaattcat
     1981 ttttccatca gtttccttta atgttttatt ttttccataa gcttgaacaa gcttggagaa
     2041 attttcccct tcatttgctt ctttttttgc tttatctgct tcttctttag tcgaaaatag
     2101 aatgatctgt gtactaactt ctggatagaa ttctttccaa gcagtgtcta gatctttatc
     2161 tgttaatttt acattggctt tcaaaccgta ttggaaagcc agcatctgtt taaagagttt
     2221 cttatatgtc tcttctgttt ggccaactgc ttttaattgt tccttgtagt ttggaccgag
     2281 ttttttgatt tgttcattat attcttttgt tacttccttt gaagaaatct cttttccgta
     2341 tacatcatca aatgctttga agacaatcat tttttttaat agtgtttgat tatttgattt
     2401 aacttttggg ttatcataaa aatcctgaac tgtaagtgtt ccacctttaa acgttgcaat
     2461 cgtttcattg gacttgctac aacctgagaa tagtaaaatt gcacatgctg aaaggcacat
     2521 aattagtagt tgttttttca aaaaatttcc catcctttcc ttattaaaaa cagtctaaca
     2581 gaagaattag ggagacagtc tttcattttc gtaaggttgc tgtagatatt cttagttcgt
     2641 aaaaatctat tctctctatg atggagaaca tttacatagt tttcacgaga caagaaagaa
     2701 aagggttgtt aaacttaata taaaggaggg atgaaagatg atcaggatta ttcggttgat
     2761 tggatctgtt ttaatagtct tagttggttt tgttttagga attcttgtca ataatgcact
     2821 tgcggatatg tttattggaa atagtgaatg gattggagca attgccggta cggtcggaca
     2881 tttagctgtt tttttactag ctttatttct tgctagtaag gtcgaaggaa aaagaataga
     2941 agattatggt gtttctgttc gaggaaaaga ctgggggtat ttagcgggag gtctcgttgt
     3001 tggaattgga gtgtttctgc ttattactag tccattatat ttgacggggg cgtatcggtt
     3061 agattcagga aacgcaaaca ttgtgccgct gataacgagt tttattttat ttattgcagt
     3121 gggggcatca gaagagcttt tattccgtgg cttttttcag catcagatgc ttagatttgg
     3181 tccgttaata gcaatgattg gatctgctgc attatttgct cttttgcacg gattgaatcc
     3241 taacatgaca tttctggcag ttttcaatat ctttttagca ggttgctttt tcagcgcact
     3301 tatctacagt acaggaagtt tatttacggc tattggtgct catattactt ggaattggac
     3361 acaaggagct attttgggta taccagtcag cggaacgcaa gaacaaggtt ttttctccac
     3421 tctgatccaa tcgcaaaata caataattac tgggggaaac tttggggctg aagcatctat
     3481 atcaactaca ttattcttgt tagtcttgat tgttggtttg ttactctatg catataaaac
     3541 aaagcggatg aagaaataca ctgctgttta tcaataaaag atgaagaaag caaggctgat
     3601 atcggtcttg cttttttaag tctgtcattg attaaacgaa aaagtaaaca aattcaagcg
     3661 aatacacgac atcttttgtt agattttcac aactgactgt cgtgttctca tcattttcat
     3721 tttatataat tcctttatca aatagaaggt aattatatgg agagtgatag aaatgaagaa
     3781 aacagcgacc gtattatttg ttattcttgg gctgagtata attgcagcaa tgattggaat
     3841 cagtacttct gcaaatgaac gggcaaatga gaatctttca tttactgtga aaactgatcg
     3901 gattgtttat gacatgacac aacaagtcat tactattcca gtcaaaccaa acaaaagcgt
     3961 gaatgctagt gatgtacatg ctgttctaac atatggttgg gatggtaatg gaagttcaga
     4021 aaaagttatt ggggaagttt atttaaaaga cgtacaatgg accgctggta ttgagtatac
     4081 aataatgatt tctgcagaac tatcgattga tgagatcaag agtaaagata aagttgattt
     4141 gattgttttt tatgatggac agatgacgat cacggagaat ttgaaaccaa gcagttggac
     4201 agttgttgga ccgccaagca gtacggatag cacaagtagt gaaagcagta cagaaaacac
     4261 gagcggtgaa agcagtacag agagtacgag cagtgaaagt agcacagaaa acacgagcag
     4321 cgaaagcagt acggagagta cgagtagtga aagtagcaca ggaagcacga gcagcgaaag
     4381 cagtacggag agtacgagta gtgaaagtag cacaggaagc atgagtagtg agagtagcac
     4441 aggaagcacg agcagcgaaa gcagcacagg aaaagtaaat aatgaacttg atttggtacc
     4501 tatcatacca actaaggaac aaaagagaaa tgcagggagc aacctaaaaa gtgtgctaaa
     4561 acagcctgat tttgtttctc gtggaattga tcatcaagaa aaagcgaaag aaacagataa
     4621 tagaaaaagc gatttaccag aaactggtag tagaaccttg aacaagctaa ttacatggat
     4681 gggtgtgtta ctcattttga ttgtaggagc aagctatttt cgttctctct tccatcgagt
     4741 gaaataaaga ataaaagcaa cagatctaaa attgaataaa acgatagatt tttgagtgaa
     4801 tatttcattc gagagtgctg tattgcctgg cgaagttgta gctttgccag atctattttt
     4861 gtttactaac atatttgaga aacaggaaat aacaggaaca caaatggaaa ataagagcaa
     4921 gaataattga caatgcacac tgcgcatggt agtatctctg aaaaatcagt aacgaatcta
     4981 tttgtacgtt attcatgtag ctgtcggaat aagtctaaat aatagataaa aaggagtatg
     5041 tactttgttt gaagaattta ttgatatcaa tgaaaggcaa gtatatcaat ttttgaacta
     5101 ttgttatgaa agagacgaga aattatatgt ggtgaaggat atcgctttag atctaaacta
     5161 caccctggct aagatgaatt cggtgattca acaagcagaa tcgttttgcg aaaggtatcc
     5221 agaatataaa ttatcttttc tttcagaaaa caagatgata aaagtcgagt tttcttctca
     5281 gtttttactg agtaaagttt attctatact tttagaggga acgattggtt atattttact
     5341 ggattcactt tacaaaggta cttatcaatc cttagaaaat cttagtcaaa aaattatata
     5401 agtttgcgta cgattcaaag aaaattaaga gaacttaata ctattttgaa aaactatcat
     5461 ttatcttgca gcttgaaaaa aggtaatccg atagaaggag aagaataccg tatccgatac
     5521 ttttttcact tgatgtattg gcagtcattc gacgaaaatc attctgatat attatcaagt
     5581 ataaaaaata aacgtcaact attagaaaaa tttgcgaaac atgcgccata tacgcgtagt
     5641 atagatagaa agaaatggat cagcctacta agaatttcgt tgcaacgaat gaaacaaggc
     5701 cactcgatta cgtatgtccc agaagagatg aacaaatttg tgcatccatt gataacaaaa
     5761 gaagagttta cgcattacat actagagcct ttttttgaag caaacttctg gtcgatgaat
     5821 cacatcactc caacagagca agcttacctt tattttatgt ttggtgtaat gaacacctat
     5881 ttggaagaag atttgttgga tactccagat aaagtacaag aaagttgggg ctggattgaa
     5941 tcgtctattg tagaaaattt tgaaaaaaac ttcaagattt gttttacaac ttcagaaaaa
     6001 aattatctat atgtcaattt ggcaatgatc catttgtatt caagggtttt tgggacaaaa
     6061 aagaaggtgg atgcttttgg aaaatcagca gaagacagag attttcagca tatatttcca
     6121 gtgatgtatc caatcatgca acagtttttt agtggggtag ctcgcagaat tccagagctt
     6181 aatacttatt atgaaaagaa cagacggttg atttttcaat actgtatgtt agtcagggat
     6241 atttttataa aacacgaaca acctgtcata ttctatattc aatcaaagta tggtaaaaca
     6301 caggaattat gggcaaagaa aaggatatta tctatgactg aacgcccaat aaaatatagt
     6361 gcatccgctg atcagttacc tgatattgtc attagcgatt atcctatcga caaaaaggca
     6421 tatgatcaaa cgaatacaca gatattttac tggaatggac aacctacaaa aaatgattgg
     6481 gcgcgtctga aagctgaaat cataaaaatc aggaatgaga aaaatagatc catattggaa
     6541 aaattggatt tcgttaatta agaaaagcag attgtttatg ccaaaattaa gacattgcaa
     6601 aaagattatt ttctttaaaa tcgacaagat gaccagaaag caagagttcg ttgagctctt
     6661 gctttctttt agttttagaa aggaacatcc tgattttatc ttcgctaaat ccagtcaaaa
     6721 gttttgcaga ttggtcgtag ataatcggtt ttttcaataa agaaggggat gtacgaatct
     6781 caatatatag ttcactcaaa ctgagttcat ctattctgtg aacaagattt ttataactaa
     6841 tagaatgagt agagagcatt tcggtcacgc cgttgtttgt caattttagt aagtggataa
     6901 attcattttt ggttagtggt tgacgaatta agttctgttc gataaacggt atatcatgga
     6961 cgataagcca acgttttgcg cgtcttgaag acgagcagcc agaacctgta tacaatttaa
     7021 tcatcataca ttcctccaat agctaagtat ttatgaaata ataacatgaa gaaatagtcg
     7081 aaaagtgcca tttagaggtg taaaataaga aaatgttgtc acgtataatg gaactagcta
     7141 gataagaaat actattaaat caagaaaaaa gaaagaaggc acaagtatgt caaacacagc
     7201 cgacgcaata gtagtgatcg atttacaaaa aggggtatgt tttgattctt cgccgataca
     7261 cgaattagaa acagtgacag cattagtgaa taaaagaatc aaaacatacg aaacgattgg
     7321 gaaaccagtt attttcgttc aacacgaaga tgctcaatta gtgccacaaa caaaaccatg
     7381 ggagctattg tcggaattat ctattcctga gcacagttat tttgtgagaa aaacccatgc
     7441 gaattcattt tataagacta atttgagtgt tttattaact gaattggact gtcattcgat
     7501 cgaattatgt ggggcacaag cagagtattg tatagatacg actgtgaagt ttgctcatgg
     7561 attaggatac cagcttatga tgtgtagagg agcaacgaca acttatgata atccttttat
     7621 gaaagcaaag gaaacaatcg ctttttacga gaaaatttgg gataaacgat ttctgacatt
     7681 tttggagcaa taagttgttt cttcgtttaa aaaaagcaga atggatactg gtttatccat
     7741 tctgctttat tacgtaaaat gagaaaataa tcctgttcta tttttatggg ataaaccatt
     7801 tattttttgt ataaaaaatg tttgcgttta catataattc tcctagaaac ataaaaagga
     7861 gtgaatagct tgagaacaaa acaagtatta aagggagcgt tggtcatctt atttgctgta
     7921 agtacaagcg tcccgcaatg gacagtatat ggagagagca tttcttccga atcggaatct
     7981 cgggaggtag aaaccacaga aactactgat gctggaaatg aaacgaaatc gagtacttca
     8041 caaacagaaa caaatactga aacaacggtt gagacatctg ttactagcac agatcaagaa
     8101 acgaccgcta ccacagataa ccaacaaaca gaagaagcaa cagctacaaa aatgtcaaac
     8161 gacgaatcct cttctgctaa agtaagtgac aaagagaatg ggacagaaaa tgatgatatc
     8221 ggtaaaggtg aaaatttcaa tggtaaagaa tatttgaatt acttcggtaa acagatgaca
     8281 gaaatactta atggaccaac agaagacatc aagtcaaaat taatagagtt attagtcact
     8341 gagcttgctg ttaatgatta tggtgtagat aaagagatta tcaaacatct gattgctact
     8401 tatctattgt acgatatcgc ttttgcaaaa aacagtgtgt tgatgtcgat gcttggaggt
     8461 acagatgatg ggacaacgcc tacagaaaac acaggcttct atccaaatac aaaacaactt
     8521 catcaaactg tactaaacaa acaagatggc aaaatgatgg atgtatatgc atattatgtc
     8581 gatcaaggtt cagataaaac agtcatgatc catggcggat ttcgagggaa ttggaataac
     8641 gggatcgtta cagaagaata caatgatttt tataaggccg ggtataattt attatttgtt
     8701 gattccagag cgactggtaa tagcggaggc gattatgtga cctatggaca atatgagtca
     8761 gatgacgtcc tttactggat aaatcaagaa gttcgagagc ggccatctca aaagatttta
     8821 ctttatggtg gttcgatggg agcagctacg atgatgtctg tattagcgaa agatattcct
     8881 gtcaatgtca aaggaattat tgaaaattgc ggatttgcat caattgatga acaactacgt
     8941 tttacgtaca gccagacagt agcccccgca ctaccggatg ccataaaaaa tcagttagac
     9001 atcattgggg atcaagagca tgaagattta tttatgggcc ttttgaaaca atactatttt
     9061 gatcaggaga tgcatttgga tacaaaagct gctctaccta cgattggaat gtcagattca
     9121 ttgcctaaat tgattatcca tggaacagca gatgatgtag tacctgtgtc taacgcgcaa
     9181 aaattatatg agttatcagg agggtataaa gatcttttat tagtagaagg agcagggcat
     9241 ggaaaggcac aggaagttga ccatgctgcc tacacgaaac atgtaacgga ctttttgaaa
     9301 gtagtgttcc atgatcagat aaacgtaaag tatgtggatg aaaacaataa aagtctactc
     9361 aaagaccagg acgaaatcca gctttacgga gcttatggag aaaattatat gacagagcaa
     9421 aagacattcg aaggatacga attagcaaat gttgaaggac cgactgaagg gatttttaat
     9481 gagacgatac caactattat tttctattac aaaaaaatcc cagtagctcc accaaaaaag
     9541 caagatccga cagagaatgc agacaataag ggaaagaatg aacctcgaga ggatcaatca
     9601 agtgatgata cgcaaccgat tcagatgaca gtgaaagtac aaaaaaagac agatgcaaaa
     9661 aaaagaatgt tgccgaaaac tggagaaaag aaacattcgc ttctcattta ttcaggtgga
     9721 tttttatctg ttagcacgat tatcacatgg atttggcgaa gaaagagagg gtaaatgaat
     9781 gaaatggttc aagcgaatag tgattgcagt accagttatc atcgtagtta ttttagtcac
     9841 tgtatttttg attaatcaaa tcacaccaaa gccgattagc ttgcttgtta gaaaacaatt
     9901 tgacacaagt gaaaaagaac aagtatatgc ccgaccagat gatttccagc aaaaaatcga
     9961 acaaatcgat ataaaaaaag aaatatccta tccttcaaag tacaaaaata ataatatgga
    10021 tatctacaca ccgaaagtgg aaaagaaaaa attaccgatt cttttctgga tgcatggagg
    10081 cgcatatgta ggaggggata aaaatgattg tcgtgattat ttggaatatc tatgttcaga
    10141 cacgcagcaa atcatcgtaa atatagatta tgaacgatca ccggaagcaa aacatcctac
    10201 accagttatc caattgaacg aagccattca agcagctaaa aaagagataa aagatcaagc
    10261 agattggtcg aatatttcga ttggtggaaa ttcggcaggt gcacaaatta gtggagaata
    10321 tttgttagca cttcaaaatg aagaaattaa aaaagctgat catcttgatc cgactttgga
    10381 gaacaagcag attacgaagt ttatttcttt gtctggtctg ttggatcctt ctgcacttac
    10441 tcaagtaagt gataaaatct ctagctttct ttatgaaaaa tgtggatggg cttactttga
    10501 taataaggac tttgaacaat cagagaaggt caaaagttta gccttggtca gacatgcgga
    10561 tcgttggacg caaaacacat tcttaacgga tggaaataca aatacgttta cgaaacaaat
    10621 ggaagaagta acttctgtat ttgagaaagc gggggtgaaa gtcacaaaag tagattatgc
    10681 ggagaaaaat gctgttttga accatgaata tcagtttgat ttcagcaata aacaagcgca
    10741 agaaacatat caaaagttag taatgttttt caaggagtaa agtcttatga tgcaaaagag
    10801 gttgtaatct gtcacttagc tccaagtcac aaggagcaat ttcaataaac aagcttttca
    10861 tggtttatga atattgtaac ttgtgactga ggagttagag atggcaaggg gcacctttta
    10921 ttcgaaattt gggaatatca cacgattatt gtcacgatct cttttacgta aattttataa
    10981 gtcagatttg ttgttttgat cgtttaaaaa aagcaacaaa tccgaagcct gcggaggcaa
    11041 gaagggacaa aaagccgagt ggtaagcaaa agaatgctgg ttccactaat attccgttgt
    11101 tattgatata aggctgggaa caaagatgaa tagcaaataa aatcaatgca ctagcgaaaa
    11161 aaagcaaaga aatatggata gctttcataa gcagcacctc cttttttata attgtatgat
    11221 aaatagatta agaatctata aatgtgacaa gtttgttagg atgtgaataa aatgatcatc
    11281 tagcgaactt gaaacaaaga tggctaatga taagcaatta atgattcagc aatcagatag
    11341 gtacaaagtt taccatcata cgtctagacc aataatagaa aatatgggaa tataatagaa
    11401 aagatttagg atacccccaa aagaatttcc ccaaaaattc gatgtatcct aaactttttt
    11461 attttacata acaatcatat caactgtgaa ataaaattac aaatgataac ctaaaatgag
    11521 gccaaaagcc agtgttatca aggaaatact taattcacca aaattttttt taatttttta
    11581 gaaaataaga aacaaaaata ataaaaaaaa gaaaagataa attttttact actgtatact
    11641 aactttgtta tcgcatctaa caagtaactc gaataatacc aatacaacct tctccaaaga
    11701 tgcgatgaca tacgttctaa cccaccgact attgatgttc tgtaccaccc ttgcagaacc
    11761 aaaaaagcca ctaccaaata tttggtagtg gctttttttg ttttatggat ttttcgcttt
    11821 ttctgttatg gtgctattct ttgatttcag aaatagtatg tcgaacttta gcgatagaac
    11881 gacgtgattc tttttcgttg taaaacatca aaatcacata tagagagtcc aaaatgctta
    11941 gttgagaaat acgggaagct aaagcttcag atcggaattc tgtttcttca gaaatagaaa
    12001 taaaaacgac atcgccaagt ttagcaaggg aagaattagc ttggctagta ataacgattg
    12061 tttttgctcc agtttttctt acggtttcag caatatggat tgtttctttt gattgccctg
    12121 tgtgagaaat caaaacagca cagtcttttt ccgtcaataa agaagcttcc atcaattgaa
    12181 tatggtaatc cgtgctgtga gaagttgcga taggggaacg caaaaattta tgataagcgt
    12241 cagttgctac aatctctgaa ccgccaacac cgaaaaaata gacacgttta gattcattga
    12301 taatagtagc cgcttttttt agatcctttt gttgtaacaa cttttttgtg tcatttaaag
    12361 ttgaaatact agactcgaac accttttgcg ccatagtgag ctcagtatct gttttctgaa
    12421 tattttcgtg gatagaaata gcagatagat cattttcttg gatcaacatg gccattttaa
    12481 aatctttaaa tccattataa ccaagttttt ttgtaaattg aaaaaaagta gagtcagcaa
    12541 tgcccagttc acttgctaaa ttgctaatag gactatgact tactttgctt ggattttcta
    12601 aaatataatc ggcgatagcc tgttcttttg ggctgaagtc gttgtacatt gttttgattt
    12661 gtagtcttat ggagacgctc atgagaattc ctcattttca taataagatt atcatttttt
    12721 ccgttctcat taatgttaaa gatacaagga gagtaggaaa aaatcaaaca aaaaatattt
    12781 ttgtaaaatc tatttacaaa aaaatttttt tgtataatga gggtataaga aatggaggcg
    12841 ctatcatgga aattggtgta attggtttgg gaaaaatggg attgaattta gctttaaact
    12901 taaaagagca ccatcacaaa gtacaaggac tcgacatttc aagtacagct gttagtcagg
    12961 caagagaaaa tgacattcct gcttatcaag agatctctga atttctagct acttttgagc
    13021 agaaaaaaat catctggtta atgcttcctg ctggagagat aaccgaaaac atgttaagaa
    13081 aactttttcc aaaactcgga ccaggagaca ttattattga aggcggaaac tcttattata
    13141 aagattcaat ccgtcgagca gaagagtttc agaaaaatga aatcggttac ttggattgtg
    13201 ggacttctgg aggaatcgaa ggagcacgac atcaagcctg cttaatgatt ggaggagata
    13261 aagaaacttt tctatccgtg gaacaattat tcaaagatgt agcaattgaa agaggatatc
    13321 tgtatgctgg tgcatccgga agcggacact tcttgaaaat gatccataat ggaatcgaat
    13381 atggaatgat gcaagcaatc ggtgaaggat tccaacttgt acaaaaaagt gagtatgctt
    13441 ttgacttgga acaagtcgca cgtgtttgga atcatggttc ggtgattcgc ggctggctga
    13501 tggaaatcat ggaagatcag ttaaacgaac atcccaattt aagtaattat cggggaatcg
    13561 tttctgcatc aggtgaagca aaatggacgg ttgaaacagc gctagaaatg gctgttccag
    13621 ttccagtaat tgcaactagt ttgttcatga ggaatctttc acaggaagaa gatagttttt
    13681 cagcaaaagt agtttcagca ctaagaaatg ggtttggcgg acatgaaata gttgaaaagg
    13741 gtgagtaaaa tgccagatta tcatatagca atcgttaatt ccagcagttt cggaagagtc
    13801 tttccacacc acttggaaag attaaagtca gttggagacg ttcatttctt tactgttgat
    13861 caagagattc caggaaaaga actagcggag ttacttaaag gattcaatat cattattgca
    13921 agtgttacgc cattttttcg acgagatttt tttgaaaaca aagatgaact gctattgatt
    13981 tcccgacatg gtattggtta caacaatatt gatttaaaag cagcaaaaga acaccagaca
    14041 atcgtatcta tcatacctgc tttagttgaa cgaaatgctg tagcagaaaa taatataact
    14101 aatttgttgt ccatgcttcg acgcacgaca caagcacaag caagagtcaa ggacgatcga
    14161 tgggaagatc gggcggagtt cgtcggtagg acgctgttta acaaaacagt tggtgtgatt
    14221 ggtgcaggaa ataccggaag cggagtaatc gaaattttgc gtaacggttt tcgctgtgat
    14281 gttctagctt atgatcctta caaatcagat ttatacatcg aaagctttgg tgcaaaaaaa
    14341 gtagaacttc aagaattact ggaacaatca gatatcattt gtttatgtgc gaatttgaca
    14401 gaagagaact atcacatgat ttctgataaa gaagtcgatc agatgaaaga aaatgtttat
    14461 ctatctaata gtgcaagagg cgctctagtt gatgaagaag cgatgattaa tggtctgaaa
    14521 agcggaaaga tcgcaggata tgccacagat gttttagaag aagaaccggg acgtcaagat
    14581 catccgtatt tagcgtttga acaagtagtg attacgccac atatatcggc ctacacaagg
    14641 gaatgtttag aagcaatggg tgaaaaatgt gtcagagatg tcgaacagat cagtcagcac
    14701 cttcttcctg aacgttctgt ccagacaaag agcaactata taaaaggatg atgaagaaaa
    14761 tggtgaacgg tttaaaagtg aaaacaggcc ctcaatttta tttatatgaa gaaggtggta
    14821 tttcaaaagt ttctgatctc ttgaaatcat acggcgcgaa aagagtactg gtcacccacg
    14881 gaacggtatc atgggaaaag gcgctaccta aattagtatt tttgaatgac gaaacgattc
    14941 aattttttta tcatcgttat tctggagaat gtagttatgc tgaagccaga cgaatagcta
    15001 caatcatcaa aaaaatgaaa tcgatttcgt agttggcgtt ggcggaggaa aactgaccga
    15061 tctagtgggt tatagtgcca atcttgcaag aatcgatttc ggagtcatcc ctactttagc
    15121 tagtaattgt gctccatgga cacctcttgc tgtcatgtat aaggagaatg gacaagcaga
    15181 agggaaaaca gaacacttat acagacaagc tgcttttttt ataacagatc cccaattagt
    15241 gattgattcc cctgttccat atttcattgc cgggttagca gatacactag caaaatggta
    15301 tgaatctgag ctcatcttag aacaagattt tttgcaagat gaatcatttt tgaagctagc
    15361 acaagatact gcgaagatct gcaaagaaga gattttgaat cattctgcta aagcaatcca
    15421 agatatggca caaagaaaac tgacatcgga gttcaaacag ctttcagaga ttatctttgc
    15481 tgttgctggt ttagttggag gattaggaga taaatacgca agaaatgtgg cagcacatgc
    15541 tatgcatgac gctatcagta aatatattcc ggaaagccat cgttttctac atggagaaaa
    15601 agtagcgtat gggattttct atcaactggc actagaaggt cgctgggaaa aaatagacga
    15661 gttatatcct ttgtatcggg aattagaact gccggtttct ctagaacaaa tgggattatt
    15721 tccgaaagat aaacagataa tagataaaat ggctgaattt attgattcga aagagaaagt
    15781 gcatttgatt cctatagagg taacacagaa atcactgata cagtcaatga tggaactgga
    15841 aggttatatc agaaagatct gaaggaggag gacacatgga aacattaagt gtagtacaaa
    15901 gtttgttgat tgctttatgg gtagccgcgg ttatgtcccg ctggttaggt ggaggagcca
    15961 cgttgacctt acgtttttct cctttgatga ctggattagt cgtcgggttg atcatggggg
    16021 aagttgcaca agcgatgatt gttacagccg ctttgcaaat gatttatatg ggggtttttt
    16081 ctccaggagg atcaatgcca gctgaaccat ctattgcagc agctatcgca gtaccagtcg
    16141 cattattagg ggatctgtcg ccagaagcag cgattgccgt tgcggtgcca gtcggattgc
    16201 tcggaagtta cttgtatcag tttcgttttt tcatcaatac ttttttaggt aaatatacag
    16261 acaaagctgt agaagatttg aatacaaaag ctatggcccg atcaattatt ctttatccaa
    16321 cggttgcctc atttttatta ttcgttccgc ttgttttcat tgctttatat ttaggggcgc
    16381 cattgatcgc tgatgtaatc aaagctttag agggaacagt cgttatccac attcttgaag
    16441 tagtaggtgg agggttagcg gcaatcggta tcgcgacaac tgtatacgtt atcggtcgaa
    16501 aagattatct ggtctttttc ttccttgctt attttatgag tgttgttttg aaatctttag
    16561 atattacgat ggttacttat gccatttttg ggattattat cgctttgatc tttgtccagt
    16621 cgcaaaaagg gaaacaagta cagcctgcca caagcaataa caattcagca tcttttgatg
    16681 acgaagatga ctatgatgac ggattttaat ttaggaggaa tgggaaatgg ctgaaataat
    16741 ggataatcaa acaggtgctc ctgaagaaat cacgaaaaaa gatgtaacaa aagcctatct
    16801 gagatggcat tttgcaaacg aaattcctca ctcttttgaa cgttacttgg cgccatcact
    16861 actatacgga atgatgccaa tcttgaaaaa actttataaa gatgaagact ctttaaaagc
    16921 agcatataaa cggcagttac tgttcttcaa cactcaatta agctggggtg gcggtgtgat
    16981 tactggccta atgtcttcta tggaacagca aagagcagaa gaagagtatg aagaaaaaga
    17041 gatcttgatg caggatgact tgatgtataa cacgaaagcg ggattgatgg gggcactagc
    17101 aggaatcgga gatgcaatcg attcaggaac cgtccaatat atttttatcg caatcgcggt
    17161 accttgggca caacagggaa gtcctttagg cgcacttttt ccttttatct gctttgggtt
    17221 gtatcaggtt ttactagggg tatttttcgc aagacaagct ttcactatgg gccgtaatgc
    17281 tacaggccta aagcaaaaca ctggtgttca gacagcgatt gaaatgctat cagttttagg
    17341 gttgtttatg atgggggtgc ttgcgggaaa ctatgtaaaa gtagaatctt cattgaaatt
    17401 tgcgatatcc ggacgtgagt ttgttatcca ggaaattctt gatcaaatcg tgccagggat
    17461 attaccttta gctgtcgtaa tgggtgtgta cttgttctat acgaaaaaag gattgaaagt
    17521 cacacaagca ttattatggc tgactggaat attaattgtg ctagcaggaa tcggtatttt
    17581 ataaaaagaa gggaacgtga ataagatggg tgtagtcaat ttagcgcgtg tggatgagcg
    17641 tttgatccat gggcaagtaa tggtaacgtt atctcaaaaa agtggagtga attccatttt
    17701 tgttgtagac gaagttgtag caaaagataa atttatgaga gatctttaca aaaatgcagg
    17761 aagccgtaca ggacaaaaaa caattgtcat tacaccagag aaagctaaat tctattggga
    17821 tgaatatcaa tttaaagaat acaattgtat tttgatcgca aaaacagtcc aaacgattta
    17881 cgacttagta aaacacggaa tccccatgga agaattgaat attggaggga ttgctcaaaa
    17941 aaatcctgat acagatcttt tagtgacgaa atctgtttat ttaaataaat cagatgctga
    18001 aaaattgaaa gaaatgaatg aacaatatgg cgtaaagaat atttattttc aagccactcc
    18061 atctgcacct aaaacaggat taaaagatgt attgaacaag tttgatttgt cataaacaaa
    18121 tgcttagaaa aaagataaag agggcgaaaa aatgaagaag aacgagctgt ttcgtgattg
    18181 ggaatttcgt tatcgctata tttaccgtaa gcgccgtaca aaaaagagta aacagcgttt
    18241 tctttcagca ttagtatcag atatttacag tatgagaaca gatgtgacag tcattgctta
    18301 cgatacgcta gcctaccgat caaaaaatat ttatgttgga gatatcgaaa aagcagagaa
    18361 agttatctgt acttattacg atacacccgt tcatgcatta ggaagttatt tcatgtttga
    18421 ttggaaagac caaaggaaaa aaacaatcta ctctatatta ttgtccttca ttttgttgtt
    18481 cagtttaggt tggtggggaa tgatgatata taacaaaaat cctcatcacg tattcgatct
    18541 gctatccgta taaacaggta tcactgtact agcatttggg agctactttt tcttattggg
    18601 aaaagcagct cgcggatggc ctagcagaca aacttttatt cgaaatactt catccatatt
    18661 aacgatgcta gaaatgatcc gtacgattga tgatccgagt gtagcgtatg cgtttgttga
    18721 tgaaggctgt tatggagaaa agggcttaga cagcgtgaga tcgggtatga aaaaagaggc
    18781 tattcttttt tatctagact ctgttggggc agatacaccg ctacagtttt cgggaaatta
    18841 tttttcaaat aaagaacagt ggctgaaaca agttgataag ttgaaagaaa aaaacgtcaa
    18901 ttatattttt agtgcaagaa aaaagcaagc gcagttcttc tatttgacca aaacagattt
    18961 acgagggaaa acatttaatt ggcaaaatgc caatcagatt attgctcttt ttcgataagt
    19021 aaaaagtgca aaacaaggag tgagaagact aatgttggaa atcatgatcg ttacacatgg
    19081 taagttgagc gaaggactga aagatgcggc ggaagtaatt gtcgggacat cgagccatat
    19141 tgaaacaatg tgcttagagt ctggggagga catccaaaca ttcggagaga aggtcaaaga
    19201 aaaattaact atgatcaaca cagcagaacc catgctagta tttgttgatc taattagcgc
    19261 aagtccgtac aatcaagcgc tcttggcagt caatgaactg actgaagaaa agaaagcagc
    19321 cacttatgtc atagggggcg tgaatctgcc aatgttgtta gaagcaatca atcatcagat
    19381 gcttcacaca ccgatagaag aagcggtgga acaaattgtc aaacaaggaa aagataattt
    19441 aactgtttgg catgcttcag cggaagaaaa aaaattagat gaggacgatt tttagaagga
    19501 aggctgaaaa gatgaagtgg ggatttagat ggtatggtga aaaaggggat tcgatcccat
    19561 taaaatatgt tcgccaaata ccgggaataa atgggataat tggaactttg ctgactaaaa
    19621 tgcctggaga tgtttgggag atttcagaaa ttgaggagtt gaaagcatct gttgagagcc
    19681 aaggactgga actgcttgga attgaaagtg tagcgatcca cgatgcaatc aaggcaggga
    19741 cagatgaacg agattactat attgataact atatacgaac aatcaaaaac ttgtctcgat
    19801 gtggggttcg attgatttgt tatagcttca aaccaatttt tggatgggcg aaaactgatt
    19861 tgtttaatga aaacaacgat ggaagctatt ctcttttata cgatcagaaa atcgtcgatc
    19921 agatggagcc aggagaaatg tatcaattga tacacagcca gtcaaaggga ttcaaattgc
    19981 cgggttggga agaagaacgg ttgaaaaaat tcgctcagct ggaaaaactg tatgaaggaa
    20041 tgaccgaaga agaattattt gaaaatctga cttatttttt agaaaaagtg attccagtgt
    20101 gcgaaaaagc agatgtaaaa atggctatcc atccagatga tccgccatgg gaactttttg
    20161 gttttcctag agtgacgaaa aatcttggcg acttgaagaa aattctaaat gcagtagatt
    20221 ctccatataa tggactaacg ctgtgcacag gatctttagg ggcaaatccg gaaaacgatt
    20281 tagttgaaat catccatgag gtaggttcgc gcatccattt tgtccacttc agaaacgtgg
    20341 agtttttagg agaaagaaag ttcaaagaaa cggcacatcc ctctacagaa ggctcccttg
    20401 atatgtatca tattatgaaa gcgttggtgc aagaagggtt cgacggtcct atacgccctg
    20461 atcatggtag aaccgtgtgg ggtgaagtgg ctatgcctgg atatggcctg tatgatcgtg
    20521 caatgggact cacttacatg caaggtctat atgaggcgat aagtaaggaa aaaccactgg
    20581 gagagcatta tgaataaaat caagctcttc atctttgata tggatggcct tttattagaa
    20641 actggacgtt tagcttatcg tgcttatgta aaatcagcac aaaagtatga ttatgaaatg
    20701 cgtaaggaag tctattattt actaactggc caaacagaaa tggcgataag agaacaaatg
    20761 ggcattttgt acggagaaga tgttccatat atcaaatggc gagaagcaat caatcaatat
    20821 aaagaaaaaa tcgtgaaaga agataagaga gtatatacga aaaaaggagc agaagaaatt
    20881 ttatcttttg caaaagaaag aggaatccat acaatcgtgg cttcgtctaa tacacgggta
    20941 aaagtagaaa tgtatttaaa aatggaaaat ctatatgcct tgtttgatca aatcatttca
    21001 ggggatgatg taaaaaaagg aaagccggaa ccagagatct ttttgaaagc ttgttcaaaa
    21061 atgaatattc ctccaagtga agcacttgta tttgaagact cgattgcagg gatcgaagca
    21121 gcaaggcgag cgggcatttt gtcttttctc atcaaagatc atttgatagg gttgcccgat
    21181 cataatggga agcataagtt gaaagtagat gtaagtttat atgaatccaa taaagcagac
    21241 tatgaatttt atgacctgca tcaagcaaaa cgatttttag aaagtaaagg gttgtatctc
    21301 taataaagag gactattttc tagtcctctt tatttattgt cctgcacgac tgagggaaca
    21361 gatgaaaaag aagtaatttt ttattttgaa gtatctacct tatttgtagt gaacaattta
    21421 gaacaaacac aaaacgcatc tactgttatc taccagtaga tgcgtttaaa gagaagaacg
    21481 agaatcgtcc atatgagggt ttc
//
LOCUS       DARPZF010000044        20938 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.046, whole genome shotgun sequence.
ACCESSION   DARPZF010000044 DARPZF010000000
VERSION     DARPZF010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20938
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.046"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            165..359
                     /locus_tag="SLE65_002042"
     CDS             165..359
                     /locus_tag="SLE65_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449332.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            628..926
                     /locus_tag="SLE65_002043"
                     /pseudo
     CDS             628..926
                     /locus_tag="SLE65_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1023..1457)
                     /locus_tag="SLE65_002044"
     CDS             complement(1023..1457)
                     /locus_tag="SLE65_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8449333.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1689..2399)
                     /locus_tag="SLE65_002045"
     CDS             complement(1689..2399)
                     /locus_tag="SLE65_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEI8449334.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2389..3249)
                     /locus_tag="SLE65_002046"
     CDS             complement(2389..3249)
                     /locus_tag="SLE65_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEI8449335.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3254..3892)
                     /locus_tag="SLE65_002047"
     CDS             complement(3254..3892)
                     /locus_tag="SLE65_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEI8449336.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3907..4206)
                     /locus_tag="SLE65_002048"
     CDS             complement(3907..4206)
                     /locus_tag="SLE65_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8449337.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4249..5733)
                     /locus_tag="SLE65_002049"
     CDS             complement(4249..5733)
                     /locus_tag="SLE65_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEI8449338.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5753..6214)
                     /locus_tag="SLE65_002050"
     CDS             complement(5753..6214)
                     /locus_tag="SLE65_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEI8449339.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6232..7299)
                     /gene="ulaG"
                     /locus_tag="SLE65_002051"
     CDS             complement(6232..7299)
                     /gene="ulaG"
                     /locus_tag="SLE65_002051"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEI8449340.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7517..8287
                     /locus_tag="SLE65_002052"
     CDS             7517..8287
                     /locus_tag="SLE65_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEI8449341.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8560..9387)
                     /locus_tag="SLE65_002053"
     CDS             complement(8560..9387)
                     /locus_tag="SLE65_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8449342.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9955..11190
                     /locus_tag="SLE65_002054"
     CDS             9955..11190
                     /locus_tag="SLE65_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HEI8449343.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12189..12449)
                     /locus_tag="SLE65_002055"
     CDS             complement(12189..12449)
                     /locus_tag="SLE65_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEI8449344.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12476..13777)
                     /locus_tag="SLE65_002056"
     CDS             complement(12476..13777)
                     /locus_tag="SLE65_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8449345.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14069..14527)
                     /locus_tag="SLE65_002057"
     CDS             complement(14069..14527)
                     /locus_tag="SLE65_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEI8449346.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14540..15871)
                     /locus_tag="SLE65_002058"
     CDS             complement(14540..15871)
                     /locus_tag="SLE65_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HEI8449347.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGRDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15882..17324)
                     /locus_tag="SLE65_002059"
     CDS             complement(15882..17324)
                     /locus_tag="SLE65_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEI8449348.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17311..18075)
                     /locus_tag="SLE65_002060"
     CDS             complement(17311..18075)
                     /locus_tag="SLE65_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HEI8449349.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18179..19054)
                     /locus_tag="SLE65_002061"
     CDS             complement(18179..19054)
                     /locus_tag="SLE65_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEI8449350.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19309..19393)
                     /locus_tag="SLE65_002062"
     tRNA            complement(19309..19393)
                     /locus_tag="SLE65_002062"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19357..19359),aa:Leu,seq:caa)
     gene            complement(19411..19482)
                     /locus_tag="SLE65_002063"
     tRNA            complement(19411..19482)
                     /locus_tag="SLE65_002063"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19448..19450),aa:Gln,seq:ttg)
     gene            complement(19492..19564)
                     /locus_tag="SLE65_002064"
     tRNA            complement(19492..19564)
                     /locus_tag="SLE65_002064"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19529..19531),aa:His,seq:gtg)
     gene            complement(19626..19710)
                     /locus_tag="SLE65_002065"
     tRNA            complement(19626..19710)
                     /locus_tag="SLE65_002065"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19674..19676),aa:Leu,seq:caa)
     gene            complement(19731..19801)
                     /locus_tag="SLE65_002066"
     tRNA            complement(19731..19801)
                     /locus_tag="SLE65_002066"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19767..19769),aa:Cys,seq:gca)
     gene            complement(19847..19918)
                     /locus_tag="SLE65_002067"
     tRNA            complement(19847..19918)
                     /locus_tag="SLE65_002067"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19884..19886),aa:Gln,seq:ttg)
     gene            complement(19930..20002)
                     /locus_tag="SLE65_002068"
     tRNA            complement(19930..20002)
                     /locus_tag="SLE65_002068"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19967..19969),aa:His,seq:gtg)
     gene            complement(20005..20078)
                     /locus_tag="SLE65_002069"
     tRNA            complement(20005..20078)
                     /locus_tag="SLE65_002069"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20044..20046),aa:Trp,seq:cca)
     gene            complement(20085..20165)
                     /locus_tag="SLE65_002070"
     tRNA            complement(20085..20165)
                     /locus_tag="SLE65_002070"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20129..20131),aa:Tyr,seq:gta)
     gene            complement(20167..20242)
                     /locus_tag="SLE65_002071"
     tRNA            complement(20167..20242)
                     /locus_tag="SLE65_002071"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20207..20209),aa:Phe,seq:gaa)
     gene            complement(20278..20350)
                     /locus_tag="SLE65_002072"
     tRNA            complement(20278..20350)
                     /locus_tag="SLE65_002072"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20315..20317),aa:Asp,seq:gtc)
     gene            complement(20360..20432)
                     /locus_tag="SLE65_002073"
     tRNA            complement(20360..20432)
                     /locus_tag="SLE65_002073"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20397..20399),aa:Val,seq:tac)
     gene            complement(20448..20519)
                     /locus_tag="SLE65_002074"
     tRNA            complement(20448..20519)
                     /locus_tag="SLE65_002074"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20484..20486),aa:Glu,seq:ttc)
     gene            complement(20534..20623)
                     /locus_tag="SLE65_002075"
     tRNA            complement(20534..20623)
                     /locus_tag="SLE65_002075"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20587..20589),aa:Ser,seq:gga)
     gene            complement(20663..20736)
                     /locus_tag="SLE65_002076"
     tRNA            complement(20663..20736)
                     /locus_tag="SLE65_002076"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20700..20702),aa:Asn,seq:gtt)
     gene            complement(20746..20861)
                     /gene="rrf"
                     /locus_tag="SLE65_002077"
     rRNA            complement(20746..20861)
                     /gene="rrf"
                     /locus_tag="SLE65_002077"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         6599 a         4390 c         3332 g         6617 t
ORIGIN      
        1 gaacaatagc cttttattat atatattatt caaattagtt atatcgagtg aaaaaaactt
       61 tcaaattgat tctttttatt tatcataaag atatagatac ataatcattt tcacttacat
      121 atatttgaat attaactaaa aacagcaaga aagaagagga tcaaatgtat tatgtagaag
      181 taaaaacaaa aggcgtcaaa aacaaacaat atgtgaaagg tatcagtaac gaatatcctt
      241 tacttggttc atggaaagaa gctgctcctt tttccaaacc atgtgccata aaaataaaga
      301 acgagctaga aaaagaactg acttgtggta aagctgttgt agatatcatc gaaaagtaaa
      361 tccaatgtat agaaaggaag atcacacatg aaaagcgacg tacaaattgc taagattata
      421 gaattagaag aagaagacgc agtgttgaca attgaaaaaa aataaatgtt tgtataccat
      481 atgattattt caatatgtat cctggaattg gagatctcgt agagctatat caagatgaat
      541 caaatatact tgtcattcat catgaaatat agagacttat aaaattgttt atttttataa
      601 tgtatcagta tagaaaggaa ataaaacatg gattatactg ttgaatttga cagtgaacta
      661 cttaagcaat ttccacaaga agaacatttc atgtataaag aagcaatttc ccacaaagtg
      721 acagagtatt tggagcataa tttttttcgt ataaagccag tgcgtactcg ttcggcaaaa
      781 ggaatatacg agatgaaagt caaaattaat aaaaaaaatt atcgcatagc atttgcttta
      841 aaaaaaatca tgtgttcatt ttttatatta gttcgaattt gcaaaaaatt gtatttgata
      901 aagaggtgag taaaaaaata aaatagctga gcattggagg atagattgag tgatactaag
      961 tctatcctct tgtttttcta aagaactaag ctagaatttt ttcttttgta cgttattata
     1021 tgttatttgt cattaccaaa aagcaccttt tttcttctag tatctatgac ataagaaata
     1081 ccacccattt cctttacttg aacaaatcct actgattcat aaaatttttt tgttttctca
     1141 gtatcatctg tcaataattc gatttggact ggtccataac tagtgatctt ctccaaagct
     1201 tcattcaaaa gcactttgcc tattccttgg cgctgatacc tcggatgaat gaggatatct
     1261 tgaataaatg cgatcgtcgc aaaatcagtg atccaacgaa cgattccgat aatcttccct
     1321 tccccattac gctttatcag agattcagat tgttcaaatg ctctagctaa ccttgcagtg
     1381 tcttttgtgt aattcgtcca accaacgctc ttatataatt cagaaatctc atcgatcata
     1441 agggaatcaa tattcatttt tttcttcctt tcttatacaa ttctccctct aataatacag
     1501 ttctttgact atttaatcta tcacatataa ctctcctgta aagattctct cgattcctta
     1561 aaattcctct ttccttttag aatgcatact ttttgataaa taaaaaggtt gtgataaatt
     1621 ttcttcacaa cctctgtttc tctctatcaa gtgttatctt ttaattttct acccttaccc
     1681 tagcatctct attgcccgta gtatgcatac tttccatgtt tgcgaaaata atgtttatct
     1741 agtaaatatt gcgggatttc acatatattg gggttgatca gctcgttttc tttggccatc
     1801 agacaaattt catctaagat caaactgttt tctactgctt tcataggtga atccccccat
     1861 gtgaacggtc catgtccata gacaagtact ccagggactt cgtttggatc taattttctt
     1921 tccttaaacg tctcgacaat cacattccct gtatgaactt cgtaagcttc tcttacttct
     1981 tctttcgtta attggcgtgt acaaggaacc ttaccataaa aagcatcagc atgagtcgtg
     2041 ccataagctg gcaaatcgcg tcctgcttgc gcccacatga cggagtgcgt ggaatgagta
     2101 tgagtaatag cagttatatc ttcaaaagtt tgatacaaaa caacatgtgt ggggagatct
     2161 gaagatggtt ttaagctatc ttcttctatt atatttcccg acaaatctgt taccaccatt
     2221 tgatctgctt gcatgcattc atatctgaca ccgcttggct taatgacgat gactcctagc
     2281 tcacggtcca cttcactcac attgccccaa gtcaatttga ctaatccgta tcgcggcaat
     2341 gccagatttg cttcaaggac acgttgcttc attgctgcaa ttttttcttc acaagacatc
     2401 atagccagcc tccttcaatt tagaacttaa gtagtctttt gcctgctgga tttctcttcg
     2461 aaagtcttgg cttttttcac tccacatttc aatcagaaat gttccatcat aatctagacg
     2521 tttcaaatgt cttaataatc caagaaaatc aacacaaccg ctaccaaaag gaacatcacg
     2581 aaactggcct gaatattctt ttgttacagg gtaagtatct tttaagtgga tagcagtgat
     2641 ataatcgatc cctttctcaa gttctcgagc cggattattt tccggccatg cggacaaatt
     2701 gcctaggtct ggatatactt gtagaaaagg tgaatgaatc tgttctttga tttctaaaaa
     2761 ttttgaaatg gagttcataa atggatcatc catgatttcc acggaaagaa tgatgccata
     2821 tttagaagct tcctttacgc tttcttttat tccttcgata aagtcttctc tggaattcat
     2881 tgatttctct tcataataaa catcgtatcc agctatttgg attactttga cgcttagatt
     2941 atgcgccaaa tggattgctt ttttcattag ttgtttcgct gcttttttct tttctggatc
     3001 agcagaacca aacggaaatc gccgatgcgc acttaaacaa atcgaatgga tacgtacacc
     3061 ggagctgaac atctcttctc tcagctcagc tatcttttct tcagaccaat ctaatcgtgc
     3121 taaccgctca tccgtctcat caatcgacat ctcgataaaa tcgaagtcca tttcttttac
     3181 aagggaaaaa cgttctttcc atgaaatatc tttgggtaac gctttttcat aaatcccaat
     3241 ttgagccatt tccttacccc cagatacgaa tgatctcatc tttgaagttt tgtgcggcct
     3301 tcatcggatc atttgctgct gtaataccac gaccagtgat aaaggtatac acatcgatcc
     3361 cttcaaataa gtgtaatgtg tgtggattta atccaccagt tacagaaaca ttaaagccta
     3421 gttcaatcag ttttttgatc ttcgataaat ctttttcacc ccaagtttca ccagataaca
     3481 gcgcatcacg gctttgatgg tagattacct gccggatacc gatgttatgc caatccatgg
     3541 cttgttcaaa agtccaattg ccgtagagtt ctacttgcaa ttcacctatt tctttttgtg
     3601 ctgcctccat agttggaatc gttgcacaac aaatgactgt catccagtct gctcctgctt
     3661 ttgcaacatt actcgccact gttcctccag cgtctgcaca tttcgtatca gcgactagtt
     3721 ttttatctgg gaacatactg cgaatacagc gaatcgcttt ttgtccttcc tgtaagcaaa
     3781 gaattgtgcc cacttcaata atatctacta catcaccaac tttcataaca tctcctaatg
     3841 catgttctaa gtcattgtga tctaacgcaa tttgcaaatt cggcctgctc atcttagttc
     3901 cttcctttac ttgttttttt ggtaccactt tgtttcagca aatttttcac tgatttcttt
     3961 gactgacatc acatttttga taccgataac tgtaactcct tttttctctg cctgagtaaa
     4021 catattcaaa aaattgactg gcgtaaaaac tacatcgtat tggccagctg aactttttcc
     4081 ctctgaaatg gcacaatgat ggattttggt aattggtacg tttagttctt tcattgcttt
     4141 ttccacactt ctcatcatca tcaagcttgt tcctgatcca tttgcacacg atactaaaat
     4201 tctcatctta atccctccat tatgagtgtt gtctaatcag attttctttt atactctctg
     4261 cttttctgca tatgtgtcat agtcttctac aatcaaaaaa taaccatcag gatttttccg
     4321 atattgtaac tgcggaatag ccaataaacc aatgacaact acggcaattc cagcataacc
     4381 taggactttc atgattactg taaacaatgg ccaagctgtt gcccagtcga acatcccgat
     4441 ataaccaccg tatgttgaca tcccaatcca tgtagcgaat aatgctgaac cgcctacttg
     4501 tatgattcct gaaagaaacg ggaacaggca agcggctttg aatccacctc ggttattggc
     4561 ataaactgct ataacggcat tatcaaagaa caacggaatg aaaccggcta tgacgatcgt
     4621 tggtgatttc aataaaatca gtaaaccaat catcaaaaac tgtcccaaag caccaaacaa
     4681 gaacccaatc gttaccgcat ttggcgaacc aaagccaaaa gtagcagcta cgtcaattcc
     4741 tggaacagct cctggtaaaa tcgtgtttga gattccttgg aaagattgag ttagttcatc
     4801 gacgaatgtc cgaacaccta attgcaagat cgccagatat accgcaaaat ttaaagaagt
     4861 cgtcataatg tagaataaga aactctgccc ttcttgcatg aattgcgctt gaatcaaata
     4921 atctttgcct agtacaatca gaatgatccc aaagaaaaat agcatgagta acgaagtagc
     4981 aaccatattc tcattgaaaa tcgacaagaa tcctggtaat ttgatatctt caattttttt
     5041 gtcttgcttg attgatctat ttttcttttc atcccgcttt ttcatccact cagctaattt
     5101 tgcaaatata aagattccga acatttgctg atgtgccact gcaaatccgg caccttctgt
     5161 caattcctgc gtgattccta ctgttaagtt agaagctact gtccaataac aacctaaaat
     5221 cagtcccata aaaatcaatg cttgtatcct acctagatca ggaaagcaaa acagtaaaat
     5281 ccaaaaagcg gtagctgctt gttgaacctg aacgtttccg gtagtgaaaa cggaacgcag
     5341 tttcgtatat ttctgaaaac ggactaataa gatatttaaa acaaatgcaa tcagtaataa
     5401 aatcatcaca tctccaaagg tacggccaaa tgtctccatt aatccagcat ccacagcatt
     5461 ttgtccaaaa taaggatctg taaccatggc atccaaattg aaccgttcct ttagtccaac
     5521 caagattggc cgaaaattat tgaccaaacc accagagcca acagtcaaaa taaagtaacc
     5581 gaccgttgcc tttaagaatc cagcgatgca ttcatgaagc gggcgtttca gcaaaatata
     5641 gcctaataac acgataaaac caatcaggta tgctggctgc gtcaagatat ttgttgcaaa
     5701 atacgtccaa atgcttaaca aaaattcccc catctttttt ctcctctatc aattaattat
     5761 attctgccat cacaacttgg taatcatcga tggagttcgt agagatgaga cgctcaacca
     5821 atccatctgt cattaataat tcggataatt tttggatatt ttctagatgt tcttctggat
     5881 cttttgctgc gagtgtaaaa aacaaactag ccgttttctc ctcattctcc ccttcacttt
     5941 caaaacggat tggctgtttc aacttggtaa atgaaatagc tgttccaaaa acaccatcac
     6001 ttttttctga agaatgcggc attgctactt gaggtgcgat cacaatataa ggaccgtatt
     6061 tttctacaca atggatgatc tcctccacat acgtttcatc aataatttcc ttatcgatca
     6121 atacaagaca gctttcggcg atagcttcac gccaatccgt gatttcttta tctgggtaat
     6181 gaatcaattg atggtcaaaa aagtatttca gcaagaaact ccccttcttt cttataaaaa
     6241 cgacggaaac ggtgtatcat tttcaatcga gaagacatct tcaaatcctc gataaaaatt
     6301 aaactcaaga tcatctttgt ttgtcggata gatgaatttc ccgcctactt gccagatata
     6361 aggtttaaat ccatacttca ggcgatcctt tttgaatttc caaatttcag tgatctcttt
     6421 tggatcagcc ataaaattag accaaatatc gtagtggaca ggaatcacta cttttgcatt
     6481 caatgactcc gccatgcgca gcatatcaac agaagtaact ttgtctgtta tccctcgtgg
     6541 gttttcacca taggccccta aacagacatc gattttgtgt tcattaccat gtttggcaaa
     6601 taaattggag taatgtgaat ctcctgcatg ataaagattc cctcctgatg tttcgaataa
     6661 atagtttact gcaatttgat ccatctcctg aggcattttt ccttttaata cctcttctgg
     6721 atcttcacaa gtgaccaacg ctgtccgatc aaacgcttct aaagctacta cattgatgtc
     6781 tttgattttg actgcatcac ctggctttac tgtaatcgtt ttttcttcag gaattcccca
     6841 tttttgccac gtgcgaacca cttcttttgg cccaatgaat gttgcttcag gacaattttg
     6901 atgaactgct gcggctgtat ggatatctag atgatcggaa tggatatgtg taacgattaa
     6961 agcgtctaca ttttttatcg caaaaggatc gattacgaaa ggctgagtac gtaaattagg
     7021 ctgcatattt tgaacgccac tcatacgcat catctgatgg ccttttttca tcatgccatt
     7081 cccatgacta cgttttcccg tcccacacca tagatcacat aaaatattcg ttccttcatg
     7141 acttttcagc caaattcccg tacagcccag ccaccacata gcaaaagttc caggatccac
     7201 tacttctgtt tcgatttctt cattcaagta tgtgccccac tcaggaaatg tttctactaa
     7261 ccacttttct tttgttactt cattgacagt tttactcatt tgcttgctcc ccccatatcg
     7321 ttgttccaac ttacaagtaa atattaatgt gtatcagcat ccatgaaaac ccttttatat
     7381 gaccgtttgt tttttatatg attttctttc agtaatcaat gattgtttca gtataataaa
     7441 gacagatatg aatgtttaaa tgaacaacta gtcaaataaa tccatggatc aagatgtccc
     7501 tcaggaggca aaagtcatga aaaactcact tgtcaatatt gaaaaacgtc aaaaagaaat
     7561 tttggaactg cttcagcaga ctgaacaact atcaactttc gaattagctg aatcccttga
     7621 tgtatctatt agtacgatac gaagagattt aaatttatta gaagaaaaaa acgagatcat
     7681 acgcaattac ggttattgtt cttataatta caaaaaccag actgattttg atcaatctgg
     7741 tcctgaaagg attaaacaag cgattgccag agaagctagt aaatacatta acgattatga
     7801 tacgctgttt atcaattcta gctcgactgc gttgaaaaca ctggattttc ttcaatctaa
     7861 ccatttgaca gtcattacaa acaacgtgaa aatcaattac tctccgcaca aagataattg
     7921 tagttatatt ttaactggtg gagagatgcg ctttccaaaa gaagcactag tgggcgacat
     7981 cgcattaaat acgatttctt cagtcaatgc agacatttgt atcattggct gtagcggagt
     8041 cgatgtagta catggggtca caacaaagat attaaatgaa tcaacgatca acgaaatgat
     8101 ggtcaacaag acaatcaaat gtaagatttt agtcgctgat catcgaaaaa tcggactgac
     8161 atcaaagttc aagattgctg atatttcagt ctttgattat ttgatcactg ataaattttg
     8221 ttctgaaaaa gtattagagg agatcagaaa tacggggata aaaaccattc aagtagattc
     8281 attttaagaa ccaggacgta aatatgtaaa taggattatc aaaaaaatga ataacaaatt
     8341 tatcgataaa tgaaaaacac gctacgctca aattgataaa ggaatcccaa gatgtatcca
     8401 tccaatcgat accatcataa tctattgctt cttttataac cgttatatgt tgcctaaata
     8461 ggaatcaaac aatatcgaaa aaaggaggta tgacaaaagt cacacctcct tttttcgaat
     8521 aaacggtatt caaatcagaa cactgatttc acaaccactt tatttcaggt cgttttcaat
     8581 cacctttacc gcgtaatcat ttccgttgaa acgcgctatt ttttttgcgt ccatatatct
     8641 ttctaaataa tcatcttctc ctaattgctt atggcaagaa gcaatttcat aaagcaagta
     8701 ttccaatgca taagtcgatt tatgtttctt attatactca atacccttct cacataattg
     8761 gattgcttta tcataatcct cgattttacg gtaataggtg gcgatatcat aatatacaat
     8821 gcagaccatc agattatcaa aatcagtctc actcaatatt ttaagtgtac gctccacata
     8881 aactttcgca aaatctaatt ctccttttga caagtagatc attgccacgt ttgcagctgc
     8941 ttgtaagtga tggatatctg tttcggtcgt ttgttccaac acttgattaa aataaaataa
     9001 tgctgcatct ggttttttcg cataaagatg atcaagcagt ccttgataaa ataaaatttg
     9061 atttaaaaga tcagaattac ttactttttc ctgatcgatc gtttgtaaaa ttttataaga
     9121 ttcttggtat tttgatacag aattcaatga ttgaatctca tttatttttt tcctgatttt
     9181 gtcttcttct gtttctacta atatatcgga gatctcgaca ttcagctttt tgcaaagcgc
     9241 acttaagata ttgatgcctg gcgacatatt cttgttttcg atattgctga cagttgcttg
     9301 ttcacaaatg ccttctgcta attgtacttg tgttaacccc tttttctttc ggtattcttt
     9361 tagtaatgct ccatctactt taatcaaaac aatttccttc cctttaaaaa attatttctc
     9421 ctttatatca tacacaaaaa aaagttctaa acaaccaaaa atgtttagaa cagaataaaa
     9481 attttaattt taaaataata ttcaaattaa acaactggcg tatctgctcc ttgatttctt
     9541 tttgtgttat ctgaataatt atcgtttaca gttataacac atagtgaaaa ttgtcatggc
     9601 gagaaagtct aagaatattt ttaaacataa ctatttcttt cttacgtgtg tataatgacg
     9661 acagcacacc tatcaattaa tataattatt ttattttttt atgttctcat gtttattttt
     9721 aatgacacaa cttctcgtat ttatctggca caacatataa atcgatcaaa aaattgttgc
     9781 gtgttttttt gaaaattgga gtttcaactt gattacaaaa tttaaattta gaagttgtga
     9841 aaacagcgag agacagttta atattcaaaa tatacatagg ctactcgaac gctgtgtttt
     9901 ttagtatact agtaagaaac gaagggatag actcattcca ataaggagga tttcatgaag
     9961 acaattcttt ttgctcctgc agtattcaat ttagctgaga caacacgaat gattgaggtt
    10021 gccaaagcta tgaaagaccg ttattactgt gtattctttg gcttttctaa aacttttgct
    10081 cctttgatca cagaaagtgg ctttgagtat catttactag cgccgatcct tacgaaaaaa
    10141 caagaagaac aaatcataaa atttgaccag ttgcgtacac ttaaaaaccc ttttaccaaa
    10201 gaaatggttg cctctcgtat cactagtgaa cagagtctga ttgctaagtt tgagcctcga
    10261 ctgattgtga caggttcgaa tgtgacaatt tttttatcgg cccgcaataa aaagattcct
    10321 ttagtatatg ttaaacccta tgctttgagt gaaccttttt ttcaatcaga gcatgcgctg
    10381 atgccccacg agttacgttt cttcggccct ttaagcaatc ccctttggca ctggacaaaa
    10441 aagcgtatag taaatacccg atggatcccc aatgccttca aacacgctgc acaaaaagaa
    10501 atgcttcctt taccaaaaac aagtttacaa atgatggatg ctgatctaaa tctcatcaca
    10561 acgcctaaac tatttttgga agaagaacag ctgccggaaa attatcgaat cgttggtcca
    10621 atttttgcta agctcagtac ttccttgcct gaagaagtgc taacttttat acagcgaaag
    10681 caacaagaaa gaaaacgtat tatctatttc gcaatgggta gttcaggcaa tccgcgtatg
    10741 ttacgcaaaa ttttgttctt cttacaaaaa caaccggatc tagcggttat tgcacctatt
    10801 gactatctgc ttgatgacat tcaatctgac tcagaagatc ttttaataac agaatatctg
    10861 tctagtcatc ttttgcatga attcattgat ttttctttta tccacggcgg ggaagggacc
    10921 gtccaaactg cctgtgaatc cggcaaaccg tttatcggtg tggggatgca atttgagcaa
    10981 agctgtaata ttgactattg tgtaaaatac ggaaacgcaa tcgccctcac aaaaccagtg
    11041 actgaaagaa aactgcagat tgctctgcgc gaagtttctt cacccaagat tcgtcagcag
    11101 gcacgcacgc tgcaagccgt ttttccaata aatggtccac aacaagcaat tcaagaaatc
    11161 gaaaccttcc tgagcaacca cccaatatag tttcaagtag aaaaagcttt tttaatagag
    11221 actcatcagt aatttcgcta ttcgagaccc agacagtgaa aatacaaaaa aagtaaatag
    11281 tggattgaaa agttagagtt acttaaatta cggtgtctaa aaaacacaaa atcatcctta
    11341 aaataaaaga tctgacgcta tccaaatgag cataggtagc gtctgccatt tattcttagt
    11401 caaattcttt gacacctttc tctggttgga tcatctcaac gtttcttcaa aagaaagacc
    11461 ataataatta ggcaaataca ttttcttaaa atgtgtcata tagatctaga agcatcgctt
    11521 tgtagagatt tgtgccgcta gtcccctcaa caattactaa atcaaatgta ggatttacca
    11581 ctttatcttt gataatcaac ctccctcttc tgttgagaca atgatctcgc aatccgatgc
    11641 atactcctat ataaactgcc agcaatcccc acatattgag tagatcatgt cagaatgttc
    11701 tatgtcgtca gcaacgatac actaaaagtc acgttcacca tgactgattg ctattcccag
    11761 cacaattatt tctatacacg tttcatgatt tgaataaaca ctcacatcat acatattacc
    11821 attcatacac catactgcag cccctactat atggttgtaa gctcccaaat ctatatttga
    11881 cttgatcact ttggtagtag atctactaat tctaaatcca ttgctgataa aatttccatt
    11941 ttttcctcct tctttctgcc aaaacagtta aaacaataat aatctttatg taaaaaaggg
    12001 ctgtgacaaa agccttgtca cagtcccata ttccgaataa acggtggtca aaagcttgca
    12061 tctgcggtaa taagttcaac caaacgaaaa ataagccaac atttcacaaa aatttaagaa
    12121 gcaattttcg taaatttctt cttatttctt gaagctaacc acttctgtta caaccacttt
    12181 tagaacattt aaagcttcga tgtgacaaac catctatgct gctcgatcat aaaattgata
    12241 gcaaaaattc cacaaagtac atatgtcccc catgaaaaca aaacattcat atgcggtaca
    12301 atgatctttg gaagaatcac gatcaaaaat gatgccagtg cccaaatcca tcgattgatt
    12361 tgaatatgat atgtagctag catattcaat ataaggtgac tagccgttaa taaaaagata
    12421 aaaacaaaaa ataaaatcag ccaatacatt gtttcccacc ttctaaaaac caaacttaga
    12481 cagtctggac ttcgttttct ccacgacttt gttcatctga cagcatcttt ttatcataag
    12541 cttttacaaa tggataatag ataataaatg ctatcaatgt gttgatcatg atcaagataa
    12601 caacacgcca gtcatttcct gctgaaagat aaccgccgat tggagctggt aatgtccatg
    12661 ttggcaaaac agtaaatcta ttgaccattt ctaatttgac tgcaaaataa ctgataatag
    12721 tcaaaactaa aggaactaag ttgaacggga tgaacatgta aggattcaac atcataggag
    12781 ctccaaaaat tatgggctca ttgatattga agataccagg aataatagaa aaacgaccaa
    12841 cctctttcaa gaattttgat ttacagaaga atataaacaa aacagatacc acgatcgttg
    12901 ctcctgcacc accaattgtt accgtccatt gataaaactg ttcaggagcg atatagggta
    12961 attgggtggc agctgtacca tctgccaatg cctttgcatt ctcatccaac atgatcagcc
    13021 acattggacg aacaacagcc cctacaatac tcatgccatg gataccaaat gaccacaaca
    13081 aatggatcaa aaacattggt agtaaaacac caagcaaatt attccctaaa atattggtta
    13141 aaggctcgaa taacgataat aaggcagcgt ttacatcaaa gcccgcgacg cttcgaatca
    13201 gccaagtaat tgttaaaatg actgcacctg gaatcaatgc ctcaaaacta cgggcaacag
    13261 caggtggcac ttgttctggc attttgatag taatatttcg atttttaaag aaacgatata
    13321 cttccactgc aaaaatcata gataagatcc ccgcaaacat cccagatgct cccaaagaac
    13381 tcataggtaa gacccagcca agaggtgcct cttcaggagt taaaacgttt acaggaactt
    13441 gtaacataaa gaacgttcct aaagataata taccacctgt cacactatct aatccatatg
    13501 atttagctag atccgaaccc ataacaaaag ttgcataaat agccatcaat cccatcgtca
    13561 tcctaaaggg taaaacaatc gttgccgaat aaggggcaat aaattcattc catccaggaa
    13621 acggtaaatt gataaagacc ataaaaaatg tcccaatcaa aatcaatgac aatgttgaaa
    13681 caaccccatt acgaattgct aataaatgac gctgtgtacc aatttttgcc attggtggga
    13741 caagtttctc ttcgacccat ttcatcagct tttccactaa aaccactcct tttcaataaa
    13801 atatgaacca ttcattgcat gacaacgcaa agaatgttca taactaatta tataattaag
    13861 aaattttatt tcaatatatt ctcttaaata atcaaattta tttttaagaa tcctgaaaat
    13921 aagttttcta aatcatagga gcaacaaaaa aattcgataa ttaacaaaaa tcaaaatgat
    13981 taaatctagt gattgaaaca tatcatttca aaaaaatttt gtaaattcac ccataaatat
    14041 caccctattt aacttttttc atcgtacact aaaattcaaa acaactatct ttaatcttta
    14101 cttcttggtt ttgttttaat aaatttcctt caaaaatgcc tggagaaact acaatgatca
    14161 ccgtatcttt ttgtgcttgc tccaacttct tcaaatctat aatagctaac agtgtccctt
    14221 cttttacctc ctggttactt tcaacccgta tctgaaacgg acttccttcg agttcaactg
    14281 tatctaaacc catatggatc agtatttttc tgccagattc actttcgatc gttatggcat
    14341 gtcgggtagg aaatatatta tcgattattc ctttaactgg cgcatggata tatccatcat
    14401 gattcgttat agcgtatcca actcctatca tttttgaaga aaagacctcg tcttttactg
    14461 ctgttaatgg aataatttga ccactagcta cagcttttag aatgtttctt gttttaaaga
    14521 aatgcacttt ttatcacctc tactttaatg ctggccaata ttttttgttt actttgatca
    14581 tttcatctag tatttttttt gcgactctgg catttggtac ggtttgattc aatgtaaatg
    14641 cttgtaaagc tttttgataa gaaccttcaa agtaagcatc tactagtaac ttctctactg
    14701 caacttgtgc ctccatcaat cctttatgaa aatcactgat tggttttctt agtgtaattg
    14761 gctccacacc agttgcacca acatatgccg gtatttcaac aactgcatct gaccgtagat
    14821 tcggaatcgc cccttgatta ggaacgatta gcataaagcg acgacgatca tcattcaaca
    14881 aggaaatagc tatatcgacg atatattgtc catgctcccc aaaattaaag ttcaatactt
    14941 cttccacaat accgcggcgt attttatcag ccatttcttt ggtatttttc tctcgtccat
    15001 ccatgaccat attagcacgt gtatactctt tgtcagtatg ctcaacgacc atatcaggat
    15061 ataagtaata ctctaagtaa ttattcggga tattacttgg aaaatttttc gtgatgactg
    15121 acatcatttg aaaggttttt tgccaagttt tatctcctat attaaaatcg gcgacttgca
    15181 tttcttttgt tattagtttt tcaataatct ctggcataat ttctcgttgc aattctttat
    15241 cataaatcga tgtataccag ccaaagtggt ttaaaccata atacgtaacg atccaattct
    15301 tacgatcata accgtaattc actgcaatcg tttcttcaat tgaaatagtc atatcacagg
    15361 cattaatcat ttttacattc ggatatttac gacgaacagc ttcagaaacg atcgactctg
    15421 gatttgtata attcaaaatc catgctttgg gggcatagtc ttgtatatga tcgacaattt
    15481 ccaataaacc tttgattgag cgcatcccat aagcaaatcc tccgagtcca cacgtttctt
    15541 gtcctactaa tccatgttta agtggaatct tttcgtcctt ttctcgcatc tccaatcctc
    15601 caacacgaat ttgtgagaaa acaaaatcgc gtcctgtaaa agcaagcttt ggatcatccg
    15661 ttgcacgaat gcgaatattt gaaaaacctt ttcttttcag cataaattta acaatcaagt
    15721 acatatccat atttctttct tcatcaatat catataaacg tatttcagat aatggcaacc
    15781 gtttttcatt gttcaaaatg gcttgaacga ttcctggtgt atacgtactc ccgcctccag
    15841 ctatagtgat aatctgtttt ttcatcatca tcttttcctt tctattcttc taataattta
    15901 ttgaattctg ccataacata agtcacttct aagccgatga taatttgata atttttttca
    15961 gttggtttaa tgatcccgct tatccctaat tgcttgattc gctgttcctc gaccatggtg
    16021 ggatccacta cctctacccg taggcgtgta ttacaactat agacatccag gatattggct
    16081 tttcctccaa acgcttgtag catttttgtt gccatatatt cataattttt acttgctaac
    16141 cctaactctg tttcttctaa ggttacttca ttgccaaact ctgccttagc ttcacgtcct
    16201 aatgtctgaa tgtttctctt attgatcaaa taataaaaag taacgtaata caaggcaaaa
    16261 aagaaaattc cgattggaag aatcaaaata gcattggtag cgattcgaaa attgatgaga
    16321 taatcaacaa tacatgctcc gaatgtaaaa ccaattcgta tattgaataa gtaacagaca
    16381 atccctgcta aaccggcaaa aagtgcatgg atcacgtaca acataggaga aagaaacatg
    16441 aaactaaatt caacaggctc agtgatattt gcaataaatg aagttcctgc accgcttccc
    16501 atgattcctt tgaccatctc tttattttct ttataagctg ctttatagat agctagacat
    16561 atagctggta taccaaacat cattactaca aaaaaaactg ataaaaacag tccagcctga
    16621 ggatctccgt tgataaagcg tgtcatctct cctctgaaaa cttccttgct aggagatgta
    16681 tagcttccta aatcgtaata aatatacgta ttcaacacat ggtgcagtcc aaaggggatc
    16741 agcaaacgat tcaaaaacat aaatatcccc acacctaatg ctcccatatc aacgagcagt
    16801 tttgcaaaat tatcaatccc aatttggatg agcggccaga taaagcccaa aaaaacagct
    16861 gcgattgttt gtagaatcat caccatagtc aatgggaatt tttcgcccgc aaaataagaa
    16921 aaaactactg gtaatttttg ttctttaaag cgattatacg tccatgccgc tactaaaccg
    16981 gaaataattc caccaaaaat ccccatattc acttctgggt ccataatttc taagcctttt
    17041 ttcaaggtag caatcgctaa aaaaccagta agtgcaggta ttcctttgtc cttatttttg
    17101 acaaaaccga ttgcaactcc tatagcaaat aagatatcca agtttccaaa aacggcattt
    17161 ccagctgcac caattactgg gatgttcagc atatcgtcag ctgataaacg catgatcaat
    17221 cccgctaatg gcatcgctgc aactggaagt agcatcgctc ttccaagctt ctgcacattt
    17281 gatttaacat tcatttttat tcctcctcta ttaaatatcc tcatatgtta ctaactcaat
    17341 caaaggatca tttttcactt tttgagcaaa tgctgaatga attaaaaatt cgacttggtg
    17401 ggtacgagga tacacaaaac ttgaaccatt taacaattcc tgatccaaat acgctgcgtg
    17461 acacatgact tcgatcgttt tatcttctct caatatcatg agtaaacttg ccaaatattc
    17521 ttccacactc gtattgattt gtcgtttttt ttcatcagtt tctcctacga catcgaaaca
    17581 aggctcaaaa taatcgacat gacgaacttc atcttttcgt tcaaagttgc tccgaaccgg
    17641 caaatcatat ttttttgcta atgtaacaac tacctcctga ttttcatcca aagtatgagt
    17701 atgatgatga ctgtctaaat gagttggtat gatccccgca tgataaattt tttgaatctg
    17761 agcattccat tcctgataca gttgatcttt gtcaatgtta aatggatgct gataataaga
    17821 taaggatctg aactctccgc tttcgataag agtatcgaca gttttgagga gtggtttgcc
    17881 acacgtcaat gttaaatgga ctcctacacc tagcctaggc atttcctttc ttagtttcac
    17941 agcatgctcg aaacccggca tatttgccat caatgtagtt gatgtcaaaa ttcctcgctg
    18001 ataagcatcc ataatcccat aattcacacc atggctatag ccaaaatcat ccgaattaaa
    18061 aatcactttt cccatttcat tctccttctt ttttctacta aaataggcgc aaccaaataa
    18121 tcatagtcca tttactatgt gtcatttggt tgcgcctata gatagttacg cccttatttt
    18181 aatagattct tgctagatga attgccaaat agatgatttc attttcttga atggcaagtt
    18241 gaaattgctg ttcgatgata tctttaatct ttagtgctgt acaatacgct ttgctatgtt
    18301 taaatgtttc agtaaaaaaa ccaatatttt ctactggcgt ttcttcctga taaatcaagc
    18361 gtttaaccag gaatttgata tgaaccatta agcgatgata agtcagtgat tctttatcat
    18421 aaacgtttga ataggatttt tctagatggg acaaaatcgt ggtcgtcatt tctactattt
    18481 ttaagctctt taaactatta ggctctccta gctcagcatt aatgatatgc atagtgatga
    18541 atcctacttc atttgaccct aactcggttt gatatcgatg attgattcgc tcgaccactt
    18601 ctactgctat atcatattca tttggataaa ggaatctcat ttctggcaac ataattgctg
    18661 tgacatctct atcttctctt tttcgttgaa tagcaaaata aatatgatct gtcaatgtaa
    18721 tatagatatt tgaatctaat ggagaggaga tcctagctgt tatcagttca atcacttctt
    18781 ccgcaaaatc cataaattcg attggaatct gcgagactat ctcactgaat cgtttgatct
    18841 tttctttaga atctaataca aataatttgt cagcatcctc aacatcaaat ggcttactca
    18901 ctttagcaga aaagccaatc cctttcccca tcgcaatttt ttctattcca tcgtcatcga
    18961 tcaatacagc attatgattc agctttttca tcacatacac cgttaattca cctcctctat
    19021 atgataaaac aaaacaactt gcagactcct tcatacatat ttttgtctcc aaacaatttt
    19081 taaagacaaa aaacgaccta agaaagaacc ctttcttagg tcgtgcctaa ttgaatagta
    19141 gcaccctaca taatttacaa aaatagttta acacataata aaagcgttat caatatcttt
    19201 tttactcgtt ttatgataat acttgtatcg aattgatttg gaggtaatta cataaaaaca
    19261 aaaaaaatat agcaactctc tataagaaag ttgctatatt gataattata ccggcggccg
    19321 gggtcgaacc ggcacgtcct caacggacac tggattttga gtccagcgcg tctgccaatt
    19381 ccgccacgcc ggcaaattta aaaataataa ctggggtagc tggattcgaa ccaacgcatg
    19441 agggagtcaa agtcccttgc cttaccgctt ggctataccc caagaataaa gggcgaatga
    19501 tgggaatcga acccacgaat gccggagcca caatccggtg cgttaaccac ttcgccacat
    19561 tcgccatcat aaaagatgtt atttaatttc tcaataaaaa actaagatga agacatctta
    19621 gtcaataccg gcggccgggg tcgaaccggc acgccctcaa cgggcactgg attttgagtc
    19681 cagcgcgtct gccaattccg ccacgccggc aagttgattt attagtacta aggcggtaac
    19741 cggatttgaa ccggtgatga aggttttgca gacctctgcc ttaccacttg gctataccgc
    19801 cattatacta ttatcaatct ataaaataaa gaataaatta tagaaactgg ggtagctgga
    19861 ttcgaaccaa cgcatgaggg agtcaaagtc ccttgcctta ccgcttggct ataccccaag
    19921 aataaaaagg gcgaatgatg ggaatcgaac ccacgaatgc cggagccaca atccggtgcg
    19981 ttaaccactt cgccacattc gccatggcag gggcagcagg aattgaaccc acactaacgg
    20041 ttttggagac cgctgttcta cctttaaact atgcccctat aaaatggagg agagtggatt
    20101 cgaaccactg aaccctaagg aacggattta cagtccgtcg cgtttagcca cttcgctact
    20161 cctccatggt ggcgcgggac agaatcgaac tgccgacaca cggagcttca atccgttgct
    20221 ctaccaactg agctaccgcg ccatatttta aaattattaa ttgaataaca agaacgacgg
    20281 ttccgacggg aatcgaaccc gcgatctcct gcgtgacagg caggcatgtt aacccctaca
    20341 ccacggaacc agttcattat ggaggttaac gggatcgaac cgctgaccct ctgcttgtaa
    20401 ggcagatgct ctcccagctg agctaaacct ccaacattca attaaaatga cccgtacggg
    20461 attcgaaccc gtgttaccgc cgtgaaaggg cggtgtctta accgcttgac caacgggcca
    20521 ggtaaatttg ctacggagag taagggattc gaacccttga gacagtttgg caccatctac
    20581 atgatttcca atcatgctcc ttcggcctct cggacaactc tccagagtga aagaagctca
    20641 atactctttc tcaaaatgag aactccggca gtaggactcg aacctacgac atcatgatta
    20701 acagtcatgc gctactacca actgagctat gccggaataa catcagcgtg gcgacgtcct
    20761 actctcacaa ggggcaaccc ctcactacaa tcggcgctaa gaagcttaac ttctgtgttc
    20821 ggcatggtta caggtgtatc cttctcgcta tcgccaccac actgtggtgt tatcttttat
    20881 tgagtaaatt ttgttcactc aaaactggat ttgaagtcac ataagttttt ttccgagt
//
LOCUS       DARPZF010000045        20784 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.047, whole genome shotgun sequence.
ACCESSION   DARPZF010000045 DARPZF010000000
VERSION     DARPZF010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20784
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.047"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(20..1576)
                     /gene="rny"
                     /locus_tag="SLE65_002078"
     CDS             complement(20..1576)
                     /gene="rny"
                     /locus_tag="SLE65_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEI8449351.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(1987..3036)
                     /gene="recA"
                     /locus_tag="SLE65_002079"
     CDS             complement(1987..3036)
                     /gene="recA"
                     /locus_tag="SLE65_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEI8449352.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(3145..4386)
                     /locus_tag="SLE65_002080"
     CDS             complement(3145..4386)
                     /locus_tag="SLE65_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEI8449353.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(4626..5204)
                     /gene="pgsA"
                     /locus_tag="SLE65_002081"
     CDS             complement(4626..5204)
                     /gene="pgsA"
                     /locus_tag="SLE65_002081"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEI8449354.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(5413..6336)
                     /locus_tag="SLE65_002082"
     CDS             complement(5413..6336)
                     /locus_tag="SLE65_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8449355.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(7075..8361)
                     /locus_tag="SLE65_002083"
     CDS             complement(7075..8361)
                     /locus_tag="SLE65_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEI8449356.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGATANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(8354..9622)
                     /locus_tag="SLE65_002084"
     CDS             complement(8354..9622)
                     /locus_tag="SLE65_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEI8449357.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            9874..10335
                     /gene="mscL"
                     /locus_tag="SLE65_002085"
     CDS             9874..10335
                     /gene="mscL"
                     /locus_tag="SLE65_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEI8449358.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(10394..10840)
                     /locus_tag="SLE65_002086"
     CDS             complement(10394..10840)
                     /locus_tag="SLE65_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8449359.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(10933..11178)
                     /locus_tag="SLE65_002087"
     CDS             complement(10933..11178)
                     /locus_tag="SLE65_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEI8449360.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(11292..11870)
                     /locus_tag="SLE65_002088"
     CDS             complement(11292..11870)
                     /locus_tag="SLE65_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEI8449361.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(11947..12477)
                     /locus_tag="SLE65_002089"
     CDS             complement(11947..12477)
                     /locus_tag="SLE65_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEI8449362.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(12481..13341)
                     /gene="rlmB"
                     /locus_tag="SLE65_002090"
     CDS             complement(12481..13341)
                     /gene="rlmB"
                     /locus_tag="SLE65_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEI8449363.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(13334..13729)
                     /locus_tag="SLE65_002091"
     CDS             complement(13334..13729)
                     /locus_tag="SLE65_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEI8449364.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(13726..15138)
                     /locus_tag="SLE65_002092"
     CDS             complement(13726..15138)
                     /locus_tag="SLE65_002092"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEI8449365.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(15135..15671)
                     /gene="cysE"
                     /locus_tag="SLE65_002093"
     CDS             complement(15135..15671)
                     /gene="cysE"
                     /locus_tag="SLE65_002093"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEI8449366.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(15757..15996)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(15993..17453)
                     /locus_tag="SLE65_002094"
     CDS             complement(15993..17453)
                     /locus_tag="SLE65_002094"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEI8449367.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(17623..18780)
                     /locus_tag="SLE65_002095"
     CDS             complement(17623..18780)
                     /locus_tag="SLE65_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HEI8449368.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(18814..20184)
                     /gene="radA"
                     /locus_tag="SLE65_002096"
     CDS             complement(18814..20184)
                     /gene="radA"
                     /locus_tag="SLE65_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEI8449369.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(20247..20774)
                     /locus_tag="SLE65_002097"
     CDS             complement(20247..20774)
                     /locus_tag="SLE65_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEI8449370.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         5472 a         4593 c         3706 g         7013 t
ORIGIN      
        1 tcttcttttg tattttttat tatttagcat aatcagttgc acgagtttcc cgaataacga
       61 ttactttgat gtgtccagga taatccagtt cttcttcgat tcgtttacga atatcacgta
      121 ctaaacgaac agcgtctaaa tccgagattt cttctggctt gaccattacc cgaacttcgc
      181 gtccagcttg aactgcgtaa cttgattcta caccggcgaa gctgttcgaa atattttcca
      241 gacttcttaa acgacggatg tagttttcta atgattcact tcgcgcacca ggtcttgctg
      301 ctgagagcgc atctgctgca gctacaagga cagagataac agaagtagct tccacatctc
      361 catgatgaga agcgatcgcg ttgattacta ctgggttttc tttgtacttg gcagctaatt
      421 ccgcaccgat ctcaacgtga gatccttcaa tctcatggtc aagtgctttc ccaatatcat
      481 ggagcaaccc ggcacgtttt gctaattgga tatcttcgcc aagctctgct gctaagatac
      541 cagctaattt tgcaacctcg accgaatgct tcaagacgtt ttgtccataa ctagttctga
      601 atcgcagacg tccgatgatc ttgattagat ctggatgaag tgtatgagca ccgacttcaa
      661 acgctgcctc ttccccgtat tcgcgaatac gttcatccat ttctttacga gatttctcga
      721 ccatttcttc gatacgcgct ggatggattc gtccatcttg tatcagtttt tccaaggtca
      781 tccgtgcgat ttctcttcgg attggatcga atccggaaag aacaactgct tccggtgtat
      841 catcgatgat taaatcgata ccagtcagcg tctcaagcgt tcgaatatta cgaccttctc
      901 gtccaatgat acgacctttc atttcatcat tcggaagggt aacgactgaa acagtcgttt
      961 ctgaaacttg atctgctgcg cagcgttgaa tcgctaatga taataagttt ttcgctttgc
     1021 gatctgcttc ttctttggca cgctgttcag attcttttac cattagagtt aactcatgat
     1081 tcagctcttc ttcagtcgat ttcatgatga catctcgtgc gtcctctttt gataaaccag
     1141 caattttttc tagttctttt tgttgatctt caatcatttt ttcaacgtct ttttctcgct
     1201 cttcaattaa ttgctgtttt gaactaagtg cttcttcttt actttcaagt gagttctcgc
     1261 gtttttctaa cgagtcatct ttacgattca gcgtttgttc gcgttgaatc aaacgattct
     1321 cttgagattt taattctaac ttactttctc tcagctcact ttcaacttca gaacggtatt
     1381 tctgattttc ttccttagct tctaacaatg cttctttttt tagagtttct gcttcttttt
     1441 ttgcactatc gatgattcca gcagctgatg attgtgcacc agctatttct ttctcgtgac
     1501 gtgactttgc gaccataaac cctaaaccaa gaccgacaat taaaccgatg atagcgagga
     1561 gaatgttgaa taccataaaa tccacctcca tactatcttt ttcattttta tcatctatac
     1621 agcttctatg ataaattatt ctaaactcgt caatatgcat cttcgcatat atgtgtacaa
     1681 aaaacatgca caactttatt ctaatgtttg taccccgtag tgtcaacttt aaataaacaa
     1741 agaaacggct ttctacttat tcattaaacg atggttttta aaataaatga cactagtttc
     1801 atataggtaa acctttaaat tgagaaactt ttctattaaa ttattctttg tagatgaaca
     1861 gatattttta ttttatgtac ccactcgtat aattaaataa ctcacgattt ctttattcaa
     1921 taaaaaaacg gcaggtcaag gagagtacct actcttcaga ccagccgttt ttgtttatca
     1981 taatttttat tcttctacta aaggcaattc ttcttgtcct ttttcatctt ctgggacagc
     2041 gacttcttca ccaataccat aagctgctct aactagagca gaaacttctg ccatcatttc
     2101 aggatgatta gccatataga ttttagcgtt ttcccgtcct tgaccaatcc gatcttcttt
     2161 ataagaatac caagcaccgc ttttatcaac aatgtctttt tctactgcca tgtctagaag
     2221 ttctccttct tgtgagatcc ctaaaccata catgacatct acttcagcga ttttgaaagg
     2281 aggtgctact ttgtttttta cgactttgat ctttgtacgg ttaccaacaa tatctgtacc
     2341 ttgtttcaat tgttctgcac gacgtacttc caaacggatc gttgcgtaga atttcaatgc
     2401 gcgtcctcca ggagtgattt ctggattccc aaacatcacg cctacttttt cacggatttg
     2461 gttgatgaaa atagcgattg tttttgtttt gttgatcgaa ccagagagtt tacgcaatgc
     2521 ttgagacatc aaacgtgctt gtaacccgac atgtgagtca cccatttcgc cgtcgatttc
     2581 tgctcgtgga actaaagcag caactgaatc gactactacg atatctacag ccccacttga
     2641 tactaaagca tcagcgatct ctagaccttg ttctcctgtg tcaggctgtg aaagaagtag
     2701 ttcatcgata ttcacaccta atttttgtgc atattgcgga tctaacgcat gctcagcatc
     2761 aatgaaagcg gccgttccgc catttttttg tacttctgca atagcgtgta gtgcaactgt
     2821 tgttttacct gaactttcag gtccatatac ttcgatgata cgtccacggg ggtaaccgcc
     2881 gacacctaaa gcgacatcta acgcaagaga gccacttgga attgtagaga tttgttggtc
     2941 gattttttcg cccaatttca taatagagcc tttaccatag ctcttttcaa tttttttcag
     3001 tgcagcatct aaggctgctt tacgatcatc tgccaatacg ataatcctcc ttatatttac
     3061 aaatcagagc aacatttcat tatccttatc atatcttttt tagtgaaaaa aagcaagaaa
     3121 aaaccgaaca aatattcgca tttatcattt tcttaaaagc tgttttctca aaagatcaaa
     3181 tccttgcata accgcattat atctgatagc agcacgatct ctggcaaagt gatatttttc
     3241 cgaaaccacg ccgtctttag atgaaatagc gatccatact gttcctgcag attgaccttc
     3301 taacgtgtcc ggtccagcca ctccggtgaa agctacactg taatctgttc ttgctatctc
     3361 acgtgcttga atggccatct gctccacaca ttctttgctg actgttccat attctgctaa
     3421 tagctccgga tcaatctcca gaaaaccagc ttttgtttgg agcgagtagg taacgaatcc
     3481 gcctggaaat acttcagata caccagcaat gtcgcctaat gcggcttgga aggcgccggc
     3541 tgtcaaactt tccgctgctg ttacagtctg cttgttttct ttcagtagtt ccactacgac
     3601 ttttgctagc gaattatcat cgccgtatcc ataaaaatat tcccctactc gttcttggat
     3661 tttttcttct aatgctaaaa gagcttgatt ccctgcctga acatcatttg ttttcactgt
     3721 cagtcgtaat gtcacttcat ttggtttggc atatggtgcg atcgttggat tgatctgtgt
     3781 ctcaatcaga tcttttagct cagtgaccag tcgcgattca ccaatcccat aaaagcgcaa
     3841 aactttagaa attagttttt cttcagaagg aaaacgttcc tctagtaaag gacgtacttg
     3901 ttccacaaac attggtttca actcattagg cggaccggga agaaggatat acgcatgtgt
     3961 atctgtttga taaaaagtcc ctaaagcaag ccctgtacga tttggtagag gaaccccgcc
     4021 ttcgataatc tgggactgtt gcagattgtt tttggtcatt tttcgatggg ttgtttcaaa
     4081 atatgccaat aattttttgt atccttccgt attttgtatg agagacttac cgaggtgagc
     4141 cgcagttgct tcttttgtca ggtcatcttc tgtcggtcct aatccgccac ataagagtat
     4201 gagttcactt cttgtttcag ctagagcaat caactcttct aaacgctgct gattatctcc
     4261 tacaactgtt tgataataaa cttcgatacc tagatcagct agctgttctg acaagaaagt
     4321 ggcattcgta ttcacgactt gtcctagtaa aagttctgtt ccgacagcta ttatttctgc
     4381 tttcattact tcccgctccc ttatatagta tacgctgtat ttttatattt ttttatttaa
     4441 aaagagggca aggagctgtg acaaaaatct tgtcacagct ccttgttcca aataaacagt
     4501 gttctcctgc caaaacctcg gtcataagtc acaatataca taaaacatga aaagctgttt
     4561 tttgaaatta tcccttgtga ctcagagtta gacggcaggc tcacaacctc tccactaaac
     4621 gatacttaca ttgatccttt gaacacaccg ctgtttttga tgaagtaatc cacacctgaa
     4681 tagatagtaa agatcagaca agcataaagc atgatttgat ctactggaat accgatcagg
     4741 ctgaatggga tattattgat aaacagcaag ataatagcaa ccatttgtgt agccgtcttg
     4801 acttttcccg gccaagctgc agccatgact tctccatgtt cgacaagtag taaacgcaag
     4861 cctgtgacgg ctaattcacg acagacaatg atcgctacta cccaaccagg ggcctttcct
     4921 tggtcaacca acatgataaa agcagtcata actagcattt tatctgccaa cgggtccgca
     4981 aacttgccaa aattagtgac aaggcctcgc gcacgggcaa tttttccatc taaccagtct
     5041 gtgatactag ctaaagcaaa aataactgca cctactagct gtgtgacagc cagtgtggtg
     5101 tctcctacgt taaattgtcc ccaatctaaa ggtaaaccta caaccaaaat gaaaatcggg
     5161 atcatacaaa ttctaagtac agttaattta tttggtaaat tcacactatc gactcctttc
     5221 ttccctattc tacgtgacta tcagcgaagt ttccaccgat attatttact tttccaaatg
     5281 aatttattca aaggagtatt tttattgaaa ttgatctttt tgaattaacg aagaaggacc
     5341 gcgacacaga tttgtcacga tccttctttt ttatacctac aagtaaacag atgcgtaaac
     5401 taatttatac gatcattctg cgtattgaag agtaaggttc acattttttg gactctgatt
     5461 gttttcccct ggattaactg gtacggattc tccattcgct ttgatcgttg cattgcttgc
     5521 tgcaccaatc gtgatggtcg catttgttgc tgtttccggt aacacggtac tctgtgtttc
     5581 atttgctgcc agtgtccctt gataaacata ggcattgtct actagcacac ctaaccatac
     5641 acgattgaca gcagtaaatt caagggttac aggcttggta gcgtctgtga tatttactgc
     5701 gatggcactg ccagaatctt ctcctgtagc tattgccatt ttcttttctt cacttgattt
     5761 tgttgttgat tctactgtag aagactcttt ggtctgcgtg ctttgctctg aggaagagga
     5821 ctcctcgact gatccttcta ctttaagcga agaagctgtg tctccgatta ttggatcagc
     5881 ttgacgatct tgccaagtca tatagcccac gacaacgaca atcgccaaag caaccaatcc
     5941 taataaaatg acaggaagac ttgtccaaaa gcgacttgga tgcgattctt cctgatgcat
     6001 tgcttttcta gaagtactta ctgtttcagg ctgcggacgt tcagggaccg atcctgtcaa
     6061 tttgcttttc ccatcaaaaa catcgactaa atggtctcca tcttctccta cagcttcagc
     6121 gtattgccga ataaatgccc gcacgtaaaa tttaccaggc aattggtcaa aatcatcatt
     6181 gtcgattgct tccaaataac gtttttgaat ttttgtaatc tgctgtaatt catctaaaga
     6241 tattttttta ttcaggcgtg cttgccgtaa tttttctccg atggtttcaa aagccactcg
     6301 ttcatcttct ccagtctgtt tgattctccg aagcatctgc tgttgcaacg aaagacgtta
     6361 tgtttgggtg ctgtgacaaa agtcatgtca cagctccttt tttccgaata aacattgttc
     6421 tcctgccaac tcctcggtca caagtcacaa tatccaataa atataagaag ctgttttttg
     6481 aacttgttcc ttgtgactcg gagttaaacg gcaggctcac gacctctttc ttaaacggtg
     6541 ttcaatcagc tgttcctcgg tattagctca aaaaccggca aaatataagg agatattttt
     6601 ccgtatgttt ctctaatact caggtcaaaa cgctgatttc acaacctctt ccttaaacgg
     6661 tgttcaaaag cttgcatctg cggtaataag tccaaccaag ttaaaaacat taagaagctg
     6721 tttttacttg gctgttctta ttacttgatg cagggcagct ttttcacaac ctcttggtac
     6781 acggtgttcc agaagtagct tcttcggcaa taagccgaaa tatcacaaaa atttgagaag
     6841 caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac aacctctttg
     6901 attacttcgt ttgattttat tttaatataa gttgattaaa agagagcatg atttgtttta
     6961 ttttctcact aatttttcca acacaactaa gaataccata aaagctgatt ttggaggagg
     7021 ttcctactac aagtctaaaa cgaaatttaa gacttttcct cataaaatac tggtttattt
     7081 tggtctcatg taaaactcgc tgaaggcctc ttcacttata aatgcttccc cagctgccag
     7141 tacgtctttc atttggatcg aatcgatgat ttcaggaaga tcaaataaag ttcgatcgcc
     7201 aaataaactt tgcgtaaatt gattggcaat atattcgatc gaatttaatg attggaaata
     7261 ttgtccaagc attttcttct tcagcaaatc gagatttgtt tctgacactt ccggatcatc
     7321 agcgaatcca agaatgattt ctttgacttt ttctgctgct ttctctggtt cgtccgtatc
     7381 tccgctgaag tccgcaaagt gaaattcacg atccaagctg aattcaaaac caaagctgtc
     7441 atcgataatt ccttgattgt acatcgctag atagtttcga gaagtattgc ctaaaatcat
     7501 ttggaacaac agattgattg ctgttttata gcgtaacagt tctgttcctt cttgcggcaa
     7561 tgtgtctaat cctttaatac caagtacaaa tttatctcgt gtaatggctg cttccaatgc
     7621 actttgtttg atgatttctt ttgtgttttc agggaaataa cgtacaattt cttgctttgg
     7681 agggaaattt tttgcttctt ggttttcccg aataagtttc atcaatttct caggctccat
     7741 cttaccaact acaaataaaa ccatattgct tggctgataa aacgtccgat agcacgtata
     7801 caagtcttga gctgtgattt tgtcgatact ttcaaccgtg cccgcaatat cgatatgcaa
     7861 tgggtgtgta ggatacaagt tatttagtat gccaaaaaac atccgccagt tagggtcgtc
     7921 ttcatacatt tggatttcct gaccgatgat tcctttttcc ttgtttacag tttcttctgt
     7981 gaagtaaggt gcttgtacaa aatcgatcag agtcgtcaga ttcttttcta cctgatccgt
     8041 cgtagaaaac agatagctgg ttttcgtaaa acttgtgaaa gcattggcgg tagctccttg
     8101 tttcccaaat aattgaaaga catcaccatc ttctttttca aacaacttat gttctaaaaa
     8161 atgggcaatt ccatctggaa ctttcacctt ttctttttca ccatagggaa taaattcgtt
     8221 atcgatcgaa ccataattcg tactgaacaa accatatgtc ttgtgatagt catttttagg
     8281 caacaaatac acggtcaaac cgtttggcag tacttcatga taaagtgttt cattgatttg
     8341 ctcatattct gttttattca tttgcatttc ctcctgctaa aaagaagatt gcctgcaatt
     8401 cgatttgctc agctacttgt tgtatctctt tgatcgttac gctctccata cgtttcaacc
     8461 attcttcatc agataatttt gtttccggca gccagctgtc caaaaaagaa gcttcgattg
     8521 ccgcttgcgg agagtctaga gaaagcagat attggtttct cagcattgct tttgtctgag
     8581 acagttccaa ctctgttatt tcaccatttc gcaaactttc taattgctcg tgaatcagat
     8641 gaagtacttg atttcggttc ttttcatcga taccggtttg gacactcatg aatcctcgga
     8701 acgtatccac gctactagag gcataataag ctagactttc tttctctctg acattcatga
     8761 aaagtttaga gtgaggaaaa ccgccaaata aaccgttaaa gaccattagc gcaaaacgtt
     8821 ctggttcatc gtaatacaca tttgtctgat aagctaggtt cagctttgct tgaacgattg
     8881 gctcacgtac ttgtcgttcc ttcacgatat tcacttgagg ttgggtataa aacagatctg
     8941 gataaactgt ttcccgcgac tcaaatggta attgcccaac tgcttcagct gctttgtccg
     9001 gatcaacatc gccgacaaca aaaatgtcga tttgatcatt tgccatcatt tcttgatagt
     9061 aggacgctag cgaactagca gtgatcttgt ccaaatcttc gactacgccc aaccctggga
     9121 tcttttgttc cgggctgttt tcaaaataaa gttcttgcaa ggcataggaa gcaaaagttt
     9181 gtttatcttc cttcaaactt tccaaatata gacgcagatt gttcttttcc aagtcaaacg
     9241 tcaactgatc aaactgatga tttttaatat ttggataaaa taaaacctct tttaaaaaat
     9301 ctaccgcttg agaaaaaagg tttggatcat tgacatattc accattcaca aaactgatcc
     9361 ctgcgtttag ccaatgtaaa tttccttttt ttctaactga taatccaaag cttgcgccat
     9421 aaagctctgc aagttgcgca cttaactttg tctgatccgg ataattcaaa ctatttgttt
     9481 ccaacatgct gctgagaagt gaacgtttcg tgatgacttc ttgttgcaga cgcgcagtaa
     9541 aacggataaa aatccggatc gttttgtatt gttttgttgg taagacatga agattcacgc
     9601 cttctgccaa ttgatacacc atatttatat gctccttttc acagttgatt gcccgcttac
     9661 tcttttaatg ggtcaacctg ccttttttac ttattcctct gcttgaaatt tataagttca
     9721 ggcaattcgc cgttttttct aaatgatgtt acactttata gtatagcata gatgtttttt
     9781 atcaaaagaa acagacggct aaaagcgtat attgtttttt tattttttat ttttcgatat
     9841 actaaagaca aataaaagaa gggagggtca ttcatgatca aagaattcaa agagttcatc
     9901 atgcgtggag atgtcttgga tcttgctgtc ggcgttgtta ttggtagtgc gtttacaagc
     9961 atcgtaaacc aagtggtgca aggcttgatc acaccactaa taggttggtt tgtcgcaatg
    10021 atcacaggta cttctgattt agaaggagca ctttcaattc ttgactggtc gccgacaaaa
    10081 ggcgtcacat ttgcgtttgg taacgttatt agtgctatca ttacatttct gatcactggt
    10141 tttgtcttat tcttagttgt caaagcggca aaccgtgcga agaatttacg ctccaaagaa
    10201 gagcaagtgg aagtggaaga aactcctact gcagaagatt atcttagtga catacgcgat
    10261 cttcttgcca aacaagtggc agaagacaat acacatccag tagagcaaac aaatctttcc
    10321 gatacttcta aataataaag aatctaaaaa aaagaaagcc gattttcagt gtcggctttc
    10381 tttttttaga ttcttaactt gctacttgtt cctttttcat gtcgatatgt ggaatatcat
    10441 cttccaaata cacatctgag attgccttga atccaaacga ctcataaaaa gcttgtaggt
    10501 attcttgtgc gccgatcacg attggttttt ctggaaaatt tttctggatc atgttaatcg
    10561 tttcttgaac aatctttctt cctaaaccat ctttacggtt gtcctgatga acaaggacac
    10621 gtccaaaatg gatactctcc gcttcttcat atactcgcgt gtaggcaagg atcttcccat
    10681 cagtatcttg aaaaaacgta tgccaagctt gtccatcaat gtcatcaact tcttgataag
    10741 gacactgttg ttccacaaca aaaactgcga ttcgttcttt gacgatcgcg taaaactctg
    10801 ctgttgacaa ttcttcaaat ttctttacct gatattccac taagcaaacg ccccctgctt
    10861 ttttattctt agcataccga ttcgcacaca aaaaagcaaa cgaaccttac gaatctcagg
    10921 ctcgtttgct ttttaaactg cttcagttaa aaattcgatc tcaactgtcc gagtaagtac
    10981 atctgaatag ctgtaagata ctcgttcaaa agaattttct tcaggatcca aatcaacaac
    11041 gaatactgaa ggataggttt ctgttaaaac gccgcggcgt tctgtttgac gctttcttcc
    11101 tgtctgagca accaacatga ttgggctgcc gatacgacct tctaaatctt tcttgattga
    11161 agctaaagtt gttggcatac agttcacctc tactatcaac tataccacat atttttaaaa
    11221 ttttcaagtt taccataaaa aaaaagaaat gcaataaaaa taaataagaa gctcattaag
    11281 atttttctaa attattcctc attataaaat ttcaagtgtt tttttatttt gagttttact
    11341 ctcccgtaag cgctcattac ttgcttgtga tccattgcta aacattcagc catgtctaca
    11401 aaatcaacgc cttgcatata ataatgaaaa attttagctt ctatttttga aaactggatt
    11461 tcgcaatttt cgattgcttc ttttaataaa agatgctgaa tcgctaaagg ttcttgcaat
    11521 gtgatctctg ctaaaaagtc tggtccttct gtctctattt tttggtcgat tgagacttca
    11581 tctttttgat cacgacgctt cagcgcgttc tgcttcctca acagagaata gatttgattg
    11641 cttataatgc ttttataata acttccaaag ctaacacctt tgcttttttc gtaagttctc
    11701 aatgcctgat ataaagcgat ccttgcttct tgttcccaat cctcagaaac ataatttctt
    11761 aaataatagg tgtttttcaa acgtagtaaa agtggaaaat atttttgata cagggcagca
    11821 aatgcttctt cgtcaccatt acgtgcagcg cgcaataact cctcagacat aaaataattc
    11881 ctccataaat tcgtttatgg aggaatctta tcatcaatga ttcatcgaac tgattagaac
    11941 gatatgttat ttattttttc tcattaaatc gtccaatttt tgggacaatt tttttaactg
    12001 ctcttcattc catggagaat tacgtcggaa atcaataaaa tgcatatctt tattttcttg
    12061 ggctattgtt ttttccgttt tttttatcgt cttatataat tcataagcag aagttcgtaa
    12121 tgctccttgg gaaaagatca tccactgttc tgctaaatcg cttgtcgcca ctgtcacttg
    12181 tgtcaaacgg tcattcagct gaccagcgat tctctcgata taactgtcag ccgtttcgtc
    12241 ttctttcgta aaaacaacat ccaactggta tttcttataa ttttgttgga tgcccggaac
    12301 tagttgggca tcgaagacaa cgatgacttc cattccttca tatttcgcat aatttgataa
    12361 acgatgtaaa agagcttctc ttgcatccgc cattttgtcc tgctttttaa gctggacaag
    12421 ttccggccac gaaccaatca tgttgtagcc gtctacaatc aacagctgtt ttttcatggt
    12481 ctactccccc tgacgttggg aaaaagcctg atacataagc aaaccagcag caacactggc
    12541 atttaagctc tggacgtgcc cggtcatcgg gatcgtcagc aattcatcca tttctttttt
    12601 caatcctgga ctcattcctt tgccttcatt accaatgact aaagcaattg atcctttggc
    12661 attccatttt tggaagtttg tgccggtcat atctgtgcca aatacccaaa atcctgtttc
    12721 tttgagctgt tgcacagctt gtaccaaatt cgtcacgcgt gcaacaggga catgttcgac
    12781 tgccccagtg gaagtctttg ttacgatagg tgtgattcca actgctcggt gttttggtat
    12841 gatcacacca tcgacgccac ttgcgtctgc tgtccgtaaa atcgacccaa aattgtgtgg
    12901 atcttcgatg ctatccaaaa tcaaaaagaa ggggtcttct tttttctctt ttgttcgttc
    12961 aatcagttgg tcaagggata aatattcata aggtgtaatc gcaagaacga ctccttgatg
    13021 cacgccgtga tcgctcaaag tttctaattt ttgtttagga acccatttga ctggcacagc
    13081 ttgttcacgt gcgatttctt tcagttcttc tactttttct cctcgtgaat cttcttgaag
    13141 aaagagttta ttccctcgcc cttgttgtag cgcttctact gcggcatggt gcccaaagac
    13201 gaaattatct tctaatgctt cttcattttg atcagaaact gactgatttc gtccagtttg
    13261 ctttttattt gaatatctat tttgtttttt gtcttcaaat ccacgtttcg attgatgttt
    13321 gtttgttctt tctttaccca tttttttcac caactttctg aatacaccag cggatcaatt
    13381 cttccatccg ctcggtttgt tttgtcaaat gcagatagcc catgagcgct tcgaaccctg
    13441 ttgcgacccg atacgtcgta acatcagcat tttttgcgct cgtatggctt ttagcatttc
    13501 ttcctctgcg ataataaagt tcttcttctt ctgtcaaaag atgttcttcc agcatttgct
    13561 gaatcaaaaa ggcttgtgca ttcgcagaaa cataattcgt tgccgcacga tgcagcttat
    13621 tgggttttgt ttctccttga tcaatcaggt ggtcacgaac atagatttcg taaatcgcat
    13681 ctccaacata agccaaggct aaaccgttca attgtgtgta atctctcatg cttctcttct
    13741 ccatcgggtt ccttgcggtg tatcttctaa taagatccct ttttctttca acaaatcacg
    13801 aatttcgtcg cttcggacaa aatcacgatt gcttcttgct tgatttcgtt cttcgatcaa
    13861 ttgttcaatc tcttcatcta ataactcttc tgctgtaaat aaaataccga agatcgaaag
    13921 ccattgcgag aataaagctt ctccttgtgc caagacagcg gcagaaactt tcggctggtc
    13981 tagataagtg ttcagccact tagcaagctc atagaccact gtgatcccat ttgctgcatt
    14041 aaaatcatcg tccatttctt cgatgaatcg ctgttctaaa ttttctaaca aagcgatttt
    14101 atccgcatca tctgccaaat tctctgaggc agtttcttgg cggaatttca aattgtcaaa
    14161 cgtattcttc agtcgttgta aattggtggc tgcttctttc atcgtcgttt cactgtagcg
    14221 gatcggacga cggtattgtg tggtcgccat gaagaaacgc aagacttgtg gatcaacgtt
    14281 tttgatcatt tcatgtacag tgatgaaatt ccctagagat ttactcattt tttcatcgtc
    14341 ttcgccaatc gttacatagc cattgtgcat ccagtaatta gcgaattttt tccctgtttt
    14401 cgcttcactt tgtgcgattt cattttcatg atgaggaaat tctaaatctt gcccgccacc
    14461 atggatatcg atcgtttctc ctaaatgttt tgttgccata acggaacatt caatatgcca
    14521 accgggacgt cctttgcccc atggtgaatc ccaagaaatc tcgccaggtt ttgcttgttt
    14581 ccataaagcg aaatctaatg ggtcttcttt ttgctgctgt tcttcccctg tacgctgact
    14641 tgctccgact tccagttcat cgatggattg gtcacttaat ttcccataat tttcaaattt
    14701 acgggtacgg taatacacat cacctgaaga ttcataagca tagccttttt caaccaacac
    14761 ttgaataaat gctaaaatat ctggcatatg atccatgact cttggatgca gtgtagcagg
    14821 ctcgacattc aacgctttcg tatcttcttc aaatgctcgg atgaaacgat cagcaacttc
    14881 tggtgctgta atacctaatt cgtttgctgt acggatgatt ttatcgtcta catccgtgaa
    14941 attcgatacg aaatcgactt tatagcctcg atattcaaaa tagcgtcgaa ttgtatcgaa
    15001 agcaatggtg ctacgagcat ttccgatatg gatataatta tacacagtcg gtccgcagac
    15061 atacataccg acatgtccct tttgtatagg gatgaattct tctttttttc tggtcaatgt
    15121 attgtagatt tttatcattc tgatctcctc actttttctc ctttgattcg aacgactttt
    15181 gctggtactc ctaccgctgt agcgtcgtct ggaacatctt tcaacacaac ggcacctgca
    15241 ccgattttgg cgttttttcc gatcgttacc ggtcctaata tctgcgcatt cgcagagagc
    15301 atggctcctt gtttaacagt tgggtgtctt ttacccgttt cttttcctgt gccgcctaat
    15361 gttacgccat ggaataaaat cacatcgtcc tcgatttctg cggtttcgcc aatgacgatt
    15421 cccattccat ggtcgatgaa cacgccagtt ccaatcgttg ctcctggatg gatctcaaca
    15481 ccagttagga aacgccagaa ttgagcattg atcttcgcca ataaaaagag ccggtgctga
    15541 tataaaaaat gagagaaacg atgccaaaac aaggcatgaa aaccagggta tgtcaaaacg
    15601 atctcagctg tcgaacgtgc agccggatcg tttctctttg ctgcatcaat cgctcgggta
    15661 aaccaactca tgactttcca ctcctttcgt aagaatttta tgtaggaaat catcttctta
    15721 taaagaaaag aagcgccttt taaataagtt tccttatcaa aagacgcttt ccgcgtggtt
    15781 ccacttttct tcataatcaa tgattatctc tgacagctaa cgcctgttat acgttcttgg
    15841 ctactttgtt tcctataaaa cagtttttcc tgttttctgt gtttcgccaa gaccactccc
    15901 agaggcattt cggcaaccat tcattgatac cttgcaccac ccggtatctc tcttgtaatg
    15961 atcagctgct tacttttttc tgttcatcgt gtttagttca gtacttgatt taaatgtgct
    16021 aatgattttt cacgaccaag caattcgatc gtttcaggca attctggacc atgcatttgt
    16081 cctgatacag ctacacggat tggcatgaaa agattttttc cttttacgcc agtttctttt
    16141 tgaacagctt tgatggcagc tttgacagtt ggagcatcta ctacttccat ttgttctagc
    16201 tgtgctttga atgcgtggag aacagtagga actgtttcac cagcaagtac ttcttttgct
    16261 gcttcattca atacaggatg ttcattgaaa aatagcgtag acagatcaac gatttctgca
    16321 gcatagctca tttgaggttg atacaggcta acgatcttct tcacccattc gattgtcttt
    16381 tcatctgggt tttctgctac acgtccatca gcgattagat aaggcagaca catgtcagta
    16441 aatgcatcta gatccattgc tttgatgtaa tggttgttta cccattgcag ttttttcgca
    16501 tcgaaagctg cgggtgattt acttaggcgt tttggatcga acattttgat caattcttgg
    16561 tgttcgaaga tttcgtcttc gcccacaggt gaccagccca ataatgcaat aaagttgaac
    16621 attgcatctg gtagatagcc taattcgcga tattgttcga taaattgcaa gattgattcg
    16681 tcacgtttgc ttagtttttt acctgtttca ctgttgatga tcaatgtcat atgtccgaag
    16741 gttggtggtg tccagccaaa tgcttcatag atcatcagtt gttttggtgt attggcaata
    16801 tggtcatctc cacgtaaaac gtgagtgatt ttcatcaaat gatcatcgac cgcaacagca
    16861 aaattataag ttggcatacc atcgcgtttt tgtatgacaa agtcgccacc gatattatcg
    16921 gattcgaacg aaatagcgcc tttcaccata tctgtaaatg cgtattctgt attgcgaggc
    16981 acacggaaac gtacaacaga ttctagacct tgtgcttctt tttctgcttg ttcttcaggt
    17041 gtcaagttcg cacatgttcc tgcgtaatga ggcatttctc ctcttgcgcg ttgtgcttcc
    17101 cgttctgctt ctaattcttc ttctgtgcaa tagcatttgt atgctcgatt gctagcaagc
    17161 agctgatcaa tcagcggttg atagatttct ttacgttcag attgacggta agggccgtat
    17221 tctccaggat tttcaggaga ttcatcccaa ttcattccca accaagcaag gttttccaac
    17281 tggctttttt cgccatcttc gatattacgt ttttggtcag tatcctcaat acgaataata
    17341 aagtctccat cattgtggcg ggcaaacaaa taattgaata atgcagttct tgcatttcca
    17401 atatgcaggt gcccagttgg acttggtgca tagcgtacgc gtactttcgt cattttcttc
    17461 ctcttctttc aaactagact ttgactaaca gcaaaaattc cgtcagttac ggcttctcaa
    17521 atatcattta tttaaagcca ctcagcacaa attttacctt ttctaaggta aatagtaaag
    17581 ccaactggtt gaatttcctt accagttggc tgaatttctt ttttattttg attgtttagt
    17641 ctttttctct gtctcttttt tattgtcgat tcctcgtcct gcatgtgcag gtttagcaaa
    17701 gatcatgcgt ccagcagctg tttgaagggc acttgttaca acgacttcga tacgttcatt
    17761 catgtaatgc tgtccatctt ctacgacaac catcgtgccg tcatcaaggt aggctactcc
    17821 ttgttggcgt tctgtcccgg cttttactac tagaacattc atcgtttcac cagggatgac
    17881 gactggtttt acggcatttg ccaacgcatt gatattaaga acaggtacat tttggaattc
    17941 agagacttta ttcaagttat agtcattggt tacaatgaca ccatctaaaa gcttagccaa
    18001 tttgatcaat ttgctgtcta cttcactgat atcttcaaag tctccatcgt acatttcgac
    18061 agatataccc tcttcttttt gcaaggcatt taggatatct aatccgcgac gaccacgcac
    18121 acgtttcaaa ctatcccctg agtccgcgat gtattgtagt tcgtaaagaa caaaattagg
    18181 gatcatcaag gttccttcta agaatccagt ctttgtaata tcataaatcc gaccgtcaat
    18241 gatcacgctt gtatccaaga ttttatattt atggaaattt tctcctgatt ttcgttctaa
    18301 cagttgactc tcaacttgac tagctgtttc ttgctcgatt tttttgcttc gtgaaccaaa
    18361 aactttcttc cattcttcga ttcgtgtcgt tcccattctc aatcccagat agcctaagat
    18421 gatcatcagt aaaatcggca atacactatt gacgaatgga atttccatat tgtaaagagg
    18481 ggtcgagatc acaacaccta aagtcaatcc gatgatcgca ccgatcgcac cgaagagaag
    18541 ataagtcaag ctgacctcac ttagtttttg ttctacttgt ttgataatag ctgagatatg
    18601 tttggccaac agcaaagata ataaaaagaa aataagtgcg cctaacaggc tgttggtaaa
    18661 tgtattattc agccatccgt ttgactgttg accgattgcc tgccaagctg agggtaaaaa
    18721 tgaaataccc aagcttgcgc cgacaatgat catcagcaaa gtaatgacac gtttttgcat
    18781 cgtttttcct ccgtttcgac aatcatttat tagttagcgg aacacacgct tcaacgtttc
    18841 agccaaagtt gctactccaa ctatctcgat tccttttggc gcttcccagt tacctaagtt
    18901 gtttttaggt aggtatactt ttgtgaagcc gagtttttgg acttctttga ctcgttgttc
    18961 aatatgactg acacgtctga tttctccagt cagtccaatt tcaccgatga aacattccgt
    19021 tggctgtgtt cctttttctt tatagcttga agcaatactg acagcgatag ctaaatcaat
    19081 cgctggttca tttaatttta ccccacctgc agcttttaag taagcatctt gattctgaag
    19141 aagcaaccca gctctttttt ccagcactgc catgatcaga gatacccgat tgaaatcaag
    19201 acctgttgtt gttcgtttgg catttccgaa catagtaggt gtgactaatg cttggatctc
    19261 taccaaaatt ggacgtgtcc cttccattgc cacaacgata gcagagccag ttgcaccgtc
    19321 taggcgttct tctaagaaaa tctgtgaagg attagcgact tcttccaatc catgctcatg
    19381 catttcaaaa atcccaatct cattcgttga gccaaatcgg ttttttactg ctcgcaaaat
    19441 ccgaaaacta tgatgttgtt caccttcaaa atataacacc gtatccacca tatgttctaa
    19501 cattcttggg ccggcgatcg agccttcttt ggtaacatga ccgacgataa aaatggctat
    19561 cccatttgtt ttagcgattt tgagtagttc tgcagtggtt tctcttactt ggctgacact
    19621 tcctgccaca cttgtgatgt ctggctgcgt catcgtttgg atggaatcaa tgataacata
    19681 atcaggggag atatgttcga tggcacgact gatttcgttc atatctgttt cagcgtatag
    19741 ataaaattct gtgttgatac ttccgaggcg ttccgcgcgt aattttatct gctctgcgct
    19801 ttcttcgccg gatacatata agacttttcc gcctatggct gctaattgct gagaaacttg
    19861 taacagcaaa gtggatttcc cgatacctgg atcgccacca atcaagacca tagaccctgg
    19921 caccacacct ccgcctaaca cacggttcag ttcttctaat tttgttttga tccgaggttc
    19981 ttttttaggg acgacgtctg cgatttttgt tggttttgct ttttctcctg tcaaacttgt
    20041 ccgagttctg cggtccgttg tatcttgttc gatttcttcg accatcgtat tccattttcc
    20101 gcaatttggg cagcgtccca agaacttagg cgacacatac ccgcaatttt ggcaaacaaa
    20161 ttgtactttt gatttttttg ccattgtacc gcctcctttt atcctaatca tgagacatta
    20221 aatcaagctt aagtatcttt aacgttttat ttactggaag aaccaaatcc gccttgacgt
    20281 tgagcagtcg tttgatcttg atctgctttt aaaaacggca aaaagatccc ttggccgata
    20341 cgctcgcctt ttttgatcac tacatccttg aaaccaaagt tggtgaattg gaacatgata
    20401 tggccttcat ttgcctcatt attgtaataa tcactgtcaa tcacacctac tccgtttgtc
    20461 aacactaaaa accgcttcaa cggattgctt gaacggttag caagctgcaa aaattcatct
    20521 tctcccatgt aagctttgat tccagtaggc acgagggttg gtttcaattg tttttcattt
    20581 tctgatacat cttttttcaa tccatctgcg actgtttcca accccttttt ccagcctgct
    20641 ttccagatac ttggaatcac gacctcttct gctgcttcaa aatcatagcc agcagcatga
    20701 tgtgtagcgc gctgcggtag attgatattt tgatctttat atttagaaat aacttcaaat
    20761 cctctttttc tcaccggttt tcct
//
LOCUS       DARPZF010000046        20181 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.048, whole genome shotgun sequence.
ACCESSION   DARPZF010000046 DARPZF010000000
VERSION     DARPZF010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20181
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.048"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            208..1014
                     /gene="proB"
                     /locus_tag="SLE65_002098"
     CDS             208..1014
                     /gene="proB"
                     /locus_tag="SLE65_002098"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEI8449371.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1011..2258
                     /locus_tag="SLE65_002099"
     CDS             1011..2258
                     /locus_tag="SLE65_002099"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEI8449372.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2334..2678
                     /locus_tag="SLE65_002100"
     CDS             2334..2678
                     /locus_tag="SLE65_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449373.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2795..3121)
                     /locus_tag="SLE65_002101"
     CDS             complement(2795..3121)
                     /locus_tag="SLE65_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449374.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3494..4696)
                     /locus_tag="SLE65_002102"
     CDS             complement(3494..4696)
                     /locus_tag="SLE65_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8449375.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4813..5328
                     /locus_tag="SLE65_002103"
     CDS             4813..5328
                     /locus_tag="SLE65_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEI8449376.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5527..5973)
                     /locus_tag="SLE65_002104"
     CDS             complement(5527..5973)
                     /locus_tag="SLE65_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HEI8449377.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6020..7498)
                     /gene="msr(C)"
                     /locus_tag="SLE65_002105"
     CDS             complement(6020..7498)
                     /gene="msr(C)"
                     /locus_tag="SLE65_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HEI8449378.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7852..8481)
                     /locus_tag="SLE65_002106"
     CDS             complement(7852..8481)
                     /locus_tag="SLE65_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEI8449379.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8465..8929)
                     /locus_tag="SLE65_002107"
     CDS             complement(8465..8929)
                     /locus_tag="SLE65_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEI8449380.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9416..10684)
                     /locus_tag="SLE65_002108"
     CDS             complement(9416..10684)
                     /locus_tag="SLE65_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEI8449381.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10915..11652)
                     /locus_tag="SLE65_002109"
     CDS             complement(10915..11652)
                     /locus_tag="SLE65_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8449382.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11719..12288)
                     /locus_tag="SLE65_002110"
     CDS             complement(11719..12288)
                     /locus_tag="SLE65_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HEI8449383.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12416..13288
                     /locus_tag="SLE65_002111"
     CDS             12416..13288
                     /locus_tag="SLE65_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEI8449384.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13630..14502
                     /locus_tag="SLE65_002112"
     CDS             13630..14502
                     /locus_tag="SLE65_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEI8449385.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14499..16457
                     /locus_tag="SLE65_002113"
     CDS             14499..16457
                     /locus_tag="SLE65_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEI8449386.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16708..17559)
                     /locus_tag="SLE65_002114"
     CDS             complement(16708..17559)
                     /locus_tag="SLE65_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8449387.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17682..18149
                     /locus_tag="SLE65_002115"
     CDS             17682..18149
                     /locus_tag="SLE65_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEI8449388.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18412..18894)
                     /locus_tag="SLE65_002116"
     CDS             complement(18412..18894)
                     /locus_tag="SLE65_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HEI8449389.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(18994..19857)
                     /locus_tag="SLE65_002117"
     CDS             complement(18994..19857)
                     /locus_tag="SLE65_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEI8449390.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         6066 a         4155 c         3664 g         6296 t
ORIGIN      
        1 tactcctatt ctaacatatc cgaggctgta aaagactttc tttacaaatt cttcaagaaa
       61 ttctgctatc ttaaagtaaa ccattaattc gttctttttc caaacgactg caagttgtac
      121 aaaaaaacta ttttttacat gactttactc gtcaaaacaa gtagaataga acgaaattaa
      181 tgagtggata tttgattgag gtgtcacatg cgtaaagaaa ttaaaaatgc aaaacgaatt
      241 attgtcaaag taggaacaag tacattgatt tatcccaatg gaaatatcaa tcttgcggca
      301 atcgatcagt tagcttttgt cctttctgat cttagaaatc ggggaaagga agtgatctta
      361 gtctcatcag gagctgtagg cgttggtatg cataaattac atttgtcaga acgtccgact
      421 ttgattcctg aacagcaagc tgcggcggct gttggtcaag ccgaactgat gaatatctat
      481 aatcaaagat tcagtgtata taatcaacag acggcacaga tcctcgtgac aagagacgtg
      541 gtagattatc ctgaaagtcg taaaaatgtg aggaatacat tggaacagct tttgattatg
      601 gacacgatcc ctatcgtgaa cgaaaacgat actgtagcag tggatgaatt agatcatctg
      661 acaaaatttg gcgataatga tcagctgtca gccatcatgg caaaacttgt cgcggcagac
      721 cttttgatcg tcctttctga tatcgacggg ttttattcag ataatccgac tacaaatccc
      781 gaggctcaga tgtatcgcta tatcgataaa atcgatgaaa agattctggc acaagcaggt
      841 ggtgctggta gcacatttgg aacaggcggt atgcagagta aattaaaagc cgcttctagg
      901 atatttgaag caaacagcgc aatgatttta gcaaatggaa aaaatccggc aattattttt
      961 gatattcttg caggaaaaga agtaggtact ttatttaagg aggacttgaa atgactgact
     1021 tgatgcaatt aggacaacag gcaaaagata gcgcgcaaca actagcactt atgcctacaa
     1081 accgcaaaaa tgagctactt gttcaaatgg cacaaaccat caaaaagaat caacaagcga
     1141 tcattgaagc aaatcataaa gacttagaaa aagcagtcga aaacaatatc agtgaaacga
     1201 tgcaagaccg cttgcagctg acacctgagc gaatcaatgc catggctaca gagatcgaaa
     1261 aaattgcttc gttagacgat cctattggaa aagtagatga gatgtggacg aacaccgacg
     1321 gattgagaat cggcaaaaag cgcgtgccac taggcgtgac cggcatcatt tacgaatctc
     1381 gtccaaatgt cacgacagat gcagctagtc tagcattcaa atcagggaat gccgttatcc
     1441 ttcgcggtgg caaagaagca ttcttctcga atcaattatt agtccaatta ttgcagcaag
     1501 tactggtcag tgctggcgaa tctccttatg ccatccagtt tgtcgatgat acttctcatg
     1561 aaactgcagg acagttgatg cgattgacag aatacttaga tgtgctgatt cctcgaggcg
     1621 gagcaaaatt aatccaacga gtcaaagaac aggcaacggt acctatcatt gaaacaggta
     1681 caggaaataa tcacgtatat atcgataaag aagcacagtt atctatggca gtgaacatca
     1741 tcgtcaatgc aaaagcttcc cgtccatctg tctgtaacgc ggcagaaaca ttgctgatcc
     1801 attctgagat cgcacctttt ttcttgccag ctattgaaaa agaactggta gaacacgggg
     1861 tctctttacg tgcggatgct cgtgcgttag aatatctaga gacggctgct ttagcagaag
     1921 acacagattg ggatactgaa tatctagatt atatccttgc tgtcaaagtg gtcgattctt
     1981 tggatgaagc aattgcacat atcaatcggc ataatactaa acattcagaa acgatcgtga
     2041 cagatagtta tgcggctagt caacgtttct taaatgaagt ggacgcggcg gctgtctatg
     2101 tcaatgcctc cactcgtttt acagacggat cggtatttgg ttttggtgca gagattggta
     2161 tctctactca aaagttgcat gcccgtggtc caatggggtt aaatgaatta acttccacaa
     2221 aatatatcat ttatggcgat ggacaaatcc gcgaataatg tttcgtgtga aacattattc
     2281 ccgccttttg ccttttttct gtaaaggttc tatccaacta gaaaggtgtc aatatgtttg
     2341 aaattttaat gatttttttt atttacctta tttctctgaa tatcgctgct tttctgggag
     2401 tcggtatttt atcccttttc tttcaattca aaaaacgaag catagggagt caacgggaaa
     2461 aatggtcgca gtattttgac aaaatcgggc aaaaagggct ggttacacgc ttgcacatta
     2521 gttacatggt tgcattatgc ttattagcga caatcaatta ctattctttt ttcgatcatt
     2581 caatcgctta tacgattacg ctactgattg ctgggatttt tcacttatct tataaatatc
     2641 agctgaataa aaaccacttg aatcggactt tccgctaaaa aatatccgta cgataagtag
     2701 agtgccttga agatcggcaa aaaactgccg gactttttag aggctgtgac aaagattttg
     2761 tcacagcctc tttttccata taaacggcgt tcgcctacca gctgcctggt aaatctgttt
     2821 cctcttcgtt aagaagcgaa aatccgtcaa atgtttcgcc atcataataa cgaagcagct
     2881 catccatgga caagttcatc gttttttctt tttcttcttc cgctgattca gccagtagct
     2941 gttcccgata cacctgatac ataccagcta ttttttgctg catcgctttt ctagtttcac
     3001 cttccgcatt gattattggc aattctttga tatagccacg ataaatcaac cgatcatctg
     3061 aaaattcaat gggtaattca acgagtgtca acccgacttc ctgaaaatat tcttccagca
     3121 tctattatcc ccccattctt tttcttaaat gaattttagc ttacctactg aaaattttcc
     3181 agtttcatta ttttgagaaa aaaagggaat gtgacaaaaa tcgtgtcaca tccccttttt
     3241 ccgaataaat ggtgttcttc tgccaactcc tcaatcataa gtcacaatat tcaacaaaca
     3301 tgagaaactg ttttttgaaa ttgttccttg tgattcagag ttaaacgaca gtctcacaac
     3361 ctcttggtaa acggcgttca aaagcttgca tctgcggtaa taagcccaac caaacgaaaa
     3421 atatgagaag ctatttttgt ttggctgttc ttatgacttg atgcaggaca gctttttcac
     3481 aacctctgat ttcttattct tcttcatttg tagcaaaata attacggtga taaatgatac
     3541 aacatacact gataagaaca atggcacctg caaaataaaa cgcatagctt tcaccaatat
     3601 gttcaccaat cacacctgca ataaatggtg ctaaagctcc accgaaaaag cggacaaaac
     3661 tatagctgga cgaagcaacg tttcgttgca gacctggtat ttccatagca atcgtcgtca
     3721 acagtgtatt gataattcct tggaaaaatc ctgctaacac aatgctgatc ggtacaagga
     3781 ctggcataga agttccagct cctaataaca gcaaacaaat aatgaataag acaaatgctg
     3841 ctaaaattgt ccgataagtc gtaaacttcc gctcaagagc cggtgcaacg aaaatcgaag
     3901 caatagccag aagcacaccc cagccaaaaa atacaaaacc gacttctaat tcagaatagc
     3961 caatcaataa aaatggcgca tacgcaagta aagtaaagaa tccgaaatta tataacaatg
     4021 cgattagtcc aactgaacga agtttatgat tgcttaacgc tttgacacct tcccaaaggc
     4081 ctacttttct ctttggtttc tcagtttcag gtaaaagtac cgctagggct ataaaaccgc
     4141 aaaacatcaa aaatgctacc ccaaaaaatg gataacgcca tgaaccactg cccaagaccc
     4201 caccgactag agggccaaca gccattccgc agccaagtgc tgcttcatac atcatgattg
     4261 ctttttctgt gttaccaact aaaatactga cgatcgttgc taaagcagta gagacaaata
     4321 aagcattccc gacaccccag ccggcacgta acccaatcag cattccgata ttcccagata
     4381 atccgccaag accagcgaat acaacgatga taaacaatcc tgtcatcaat gtttttttca
     4441 aaccgatccg actagataag aaacctgtaa atagcatcac cacaccagtg actaacatgt
     4501 aactagtaaa taacagggtc gtttcagctg gcgtagcgtt taactgtgca gcaatcgttt
     4561 ttaagattgg gtctactaga cccactccca taaaagcgat catacaggta gctgctacaa
     4621 ctagcgctga acttttcccc tttgtttctt catttgtttg ttcttgtata tctatttgat
     4681 tctccaatat ttccatccct ttctctctat tagcatcata catgatttat tttacatgta
     4741 aatatgcaca tgtaaaacgt ggaaacttta ctgtgatata ataaagaaaa taagacgaga
     4801 ggtaggattt ttatgaatac tttagcctat atattattat gcgtgctttt atccaaacca
     4861 cgttctgggt atgaattgaa gcagctgatc acaatttttt gggaagccca tcacagtcag
     4921 atctatacaa cgcttgccaa gttagaccag cagggttatg tgaccgtttt ggacaaagac
     4981 gagcactctc aaaaaaagat ctaccacttg actgatgaag gacgtgctct tgtagaggaa
     5041 tggatcaaag aggaaactcc cgctcctacg caaaaagatg aatttctagc aaaaatctat
     5101 gctttttcga cgctcgataa aacaacagct actggactgc tattcactag agaacaacag
     5161 ctgaacaaaa tcatgcaaaa aaatcaaaaa aaattgaatg acctctcgct agacaagaaa
     5221 caagaatttg gacgttatgt tgtgatccag cgcagaatta tgctttgtca gcaggaactc
     5281 caatggtgtc agcaagtaag agaacaaatg cagcagtttt ttgagtaagg gataaacaga
     5341 acctttctag aaatatctat tgaagagcaa attatcttca ataaaagagc aatacagttg
     5401 gaaaagaaaa agcgatccga acgacaggcc aaaacctatc gttcggatca ctatttttct
     5461 agaactgcat tcaagagact atgacaaaaa gcatgccaag gccttttttc aaataacagt
     5521 gttccatcat tcattacttt gaattgcttt tagcacactt cttgaaagcg ggccaacgat
     5581 gatcaactgc aacggtaaag cggcaatcac attcattttc caagcattca tataagcaga
     5641 gaataattga tcaggtattc cttgttccat gatcacaccg aataaagaca tacatgtcac
     5701 cattcctaaa accatcaagc atgaaatagt taagatcatt tggaccttgc tttctggatt
     5761 tactggtagt ttaaaggcaa tttttttcgc cagcacaccg atgatgaaga catccaaaat
     5821 gaaagccacc acgaatccag gcactagacc aatcaacaaa cttgataaat gaagatcttg
     5881 atgcagccat aaattatacg cgctcatccc caagaccatc aaaaaacaca tcattgttgt
     5941 aaaaattatt ccttcttttt tatttgtagg caatctgtac cactccttta aatttgtcac
     6001 gaaaatcatc gtagcacatt taaaaatttc tcgtaagtac tttttttatt ttctgccctt
     6061 ttatttcata aacttcatca gccgtacgct cgacaaagta agaatcatga gaagtaaaca
     6121 aaatcgttcc cggatatatt tgcattagct tctctaaagc ttcgatcgtt gccatatcaa
     6181 taaaattagt cggttcatct aacagcaaca cattacttgg cttagtaaaa agcaaagcaa
     6241 tcgtcagacg ggtcgcttct cccccactta atgtacataa cggtttcgtc aaagtttcct
     6301 gagcaaaccc taagtgattc agcaaactac ggacaagcga ttctgaaaac tctgtttgtc
     6361 tcatgacaaa acgaatgatg gattcttcag atgtcatttg ataacccttt tgctgatata
     6421 cttgaaagct tactttcgga gagagaagga ttccttctcc ttgtttgcgg atatgttcta
     6481 ataaggttgt cttacctgaa ccattttcac cgacaatcgc gattttttta cctaaagaaa
     6541 actgaaaatc accatttacc agtaatgttc tcccacttct ttccaattgg acattttgtc
     6601 ccatgatggg atagcggctg tggagttcaa gagattttgg tactggaaaa cggatttgtt
     6661 tcatctgctg cggcttggtt gtttctccta ttttttggag tcttctctct aatgttttcg
     6721 cattcttttg gatggctttt tgtacactgt ctttttgttt agaggaagac aaccgatccg
     6781 gtctgatttg ttgctttttc tttttactgg acactttttc caacttttcc gcttgttttt
     6841 tcttttcttg gatcgatttt tccaatcgtt ttttctcttt catgatcgac tctgcttctc
     6901 gtagctgagt ctttttctcc aattcctttt gagtgagata ggcactataa ttccccgaaa
     6961 actctcggat ttctccgtct tttacttccc agattttcga tgctagctca tctagaaaat
     7021 agcgatcatg actaacaaaa accagcgtac cataataata acgaagctct tcaatcagtc
     7081 gatcaatact ttttctatct agatgggttg ttggctcgtc tagaagcatc ccttgttcat
     7141 aagaagaaag aagacgtatc aactcgatct ttcgttcttc ccctccgctc catttccgct
     7201 ctgaagtttc ttccagtctt aactggaaat gactggctaa ttccaaattt aggtcctttg
     7261 cttcagcgag ataggttaat tgaggcaggt agttgaaggt gatctctgtt tggattttcc
     7321 catgatcggg aaaaagttca ccggctatta gtttgagcaa agtcgattta ccgacaccat
     7381 tttctcctat gatccctata cgatcttgct gatagacacg aagagaatca atagatagtt
     7441 ctagctggtt gccaaagctg acttgtagat ttgttatatt tactgctaaa ttttccatat
     7501 gttttacact cctatttcat gtaaaacaac aattatcgat actaaaaaag agcagaaaaa
     7561 tctgtttgca aaaaaactgc atcacatctt ttcctactct gaacgaaata actatgacta
     7621 aatcaccaaa tctgtcatag ctttcaccta ttctactgtc gttcgaaaaa atggacatac
     7681 tccatccatg aaattgttgt ttatacatgt cttttgaatt tatttagttg ttattcaaaa
     7741 gttcgaaacg taatttcatc gatgcagtca tttttccgac ctcctttttt attaggttac
     7801 cacacacgat tcaaaaaaag caatagctac tgaatagtaa ctgaaaacct tttattcgaa
     7861 cgtagtgatc ttttctggtg ctaaacgaac agactcgtaa ccttcttcta ccgcttttcc
     7921 tattgataaa ataataactg gaacataacg gtctttatcc aaaccaaatg cctctgccaa
     7981 ctgatctgct tcgaatccac caattggatt tgtttcatag ccatgatcac gcgcaactaa
     8041 catgaattgc atagccgcta agctagaatc gactttgact acatcgttca tttcttctct
     8101 tgaaaaactc ttgtaataag gaatgatcgc agctaattgt tgatctctga cttcttttgg
     8161 catcttccct gattcgtaag cttggttata gatttcttcg ccatattcgt aacattgcat
     8221 atcgccaaaa atcatgacca ttgcagaaga agtatcattt tgtctcgtat tgaaacggat
     8281 caaaggacgc aagatttctt ttgcttcctc gctttcagcg accacaaagc gccatggttg
     8341 catattgaca gaagaaggtg cagtcgtcgc ttctttgatc atttccagca tttcttcgtg
     8401 tgggattttg tatgtttcat catatacgcg aacggatctt ctaccagtca taattgttga
     8461 aaaatcattt ttttgttcca ttattattaa cctctttcgt ttctgttgtt atattgcaaa
     8521 gttgggtatt caatttatct aaaagtgtta gaaattgttt catttctaca tcgctgaaag
     8581 ccggggatag cacggaacct gtatctttat ggtccatttc acaatgctcg attttcttct
     8641 gggctttttc tgttagcgct acatacactt cccggttgtt ctgaggattt ctctgacgcg
     8701 aaacatagcc atttgcttcc aataccttca gatgacgagt aactgctcct tgatcaatct
     8761 gcaacttttc ttgcaaactg ctttgtagca atggattttc ttctttcagt ctcatcatga
     8821 tctcgtatct agtaagactt ataccgatat tttcttcaaa gatctggacg attttttgat
     8881 cggctaattt gatttgatat aaaaggtgac taatctcttc taaagacata atttcctcct
     8941 ttctaataat tgactcgtca acgattgact tgtcaataat agaataaaaa aagaaaaaag
     9001 tcaaagaatc agctgtgtaa taaaaaaaac gctctcaata gaaaagtata gagaaaagaa
     9061 attttttgta gaatgaacgg aaaaaatgat aaagaaagca caacgctaaa accaagatta
     9121 ttgattctta tcaaactata gaagatagct cttctgcagt agaaaatttt acaccgccaa
     9181 aaatttccga aatcgccttt tgcaagaatc ccgtcgaata ttagaaattg gatcagtatg
     9241 cttaaacagt aataaaaaag ttatgacaag atgttgtcac aacctttttt gagtaaacgg
     9301 tgttcaaaaa cttgcatctg cggtaataag ttcaaccaaa caaaaaacat gaaaatctgt
     9361 ttttgtttgg ctgttcttac tacttgatgc agggcagctt tttcactacc tctttttaat
     9421 aaccataaaa tcctattcct tcatatctcc agcccatcgg tgttagccaa tctctttcct
     9481 tagcactcaa ggtatagtga tgggtaccag ttttttcatt tggattaaat agtcgataaa
     9541 ttggcttgga accaccagaa taaaaactta gaccttcata acgccaaccg atttttgtta
     9601 aagagttgat ctcagattgt gccattgtgt aatgatggtc tccactgtaa ggattgtata
     9661 aacggtagac aggttgtccg ctgtttggtg cttgccaagc aatcccttca tattcccagc
     9721 ctacagttgg cagataattt ttttctccgg cattcaatgt atataaatgt tctcctgtat
     9781 gacggttata cagacgatac atcggagaag ttgaagttgg tgctgtatca tactgtgtca
     9841 gattataggt ttcgattaca ttgttcaatg tagaaccata attaggcgca gtggcataac
     9901 gacctgttag ccaagccgta gcatctttgt aagagttcgt attgcttttc catgcaccgg
     9961 aatagtagta aacgcctggc tgaaaagaag tcgtcttcaa taccgttacg ttatcttgca
    10021 atgattcttt gtacgaagga tattttctaa aagcggcatt caccgtaatc cattgcccat
    10081 tcacatattc cgaagtaggc atcgtaacag attggccatt atagcttcct ttaatcccaa
    10141 atagattgta attaggggca gaagccaaag tactgttccc ccagccactt tcaacgatgg
    10201 cttgagcaat catgactgat gcatataagt cattggcact tgccaaactt tgtgcagttg
    10261 aggcaatact atcaatgaac gcttgttgag aattagcaga tgagcgagca taaaaagcat
    10321 agccagtata gttttcgaat tcagacaaat ctgcttgatg ggtatgtgtc aatgtttgcc
    10381 catctgtcaa ttggttcgtg atttcttctg cattctctgg attgttctga gcttctgctg
    10441 atgtactgtc ttcggtttgt gtttgttctg ttgtttcagt tgttggttct tcggttgaaa
    10501 ttgtattttc tgagacagta gctgactgca aagtactctc tgtatcgttt tcaattcctg
    10561 tttctgaaga actcgatgtc tgagttgcga cagtttctgt cgattcttca gctagcactg
    10621 ttgtgttggc aactgctaga tttcctaaaa gaataacgct aaataataaa ttctttgctt
    10681 tcatcttttt tctcctttga attatgaaac ttttcctaaa taacagtgta actaaaaaag
    10741 taaaagcaag tcaatgtcca tatttaaata acatttgttt ctttttgatg aatttgcttt
    10801 ttctacataa aaagacgtaa atgaagaata ttcttctcca ttcacgcctt aaattgatgg
    10861 tcgtttgaat aactatttaa caagtaattc tctttggata ttatccgtta tggattatac
    10921 ttcctgtgtc gtcggacgga taatcatgtt actgacagac atccggtctg gcgtttctat
    10981 cgcaaatgct acagcagaag ctatatcttc ggaggtcaat ccccattctt tttgcgcttc
    11041 atgaagttca agagcagcct ttttgtcgct gatggtttga tataattcag tttgaacagc
    11101 tcctggagag atgatcgtag atttgatgtt attttgccgt tgctcttgac gtaatccttc
    11161 catgattgca cggacagcaa attttgttcc gcaataaacg gcggaatcag gataaacaac
    11221 atgtcccgcc acagaatcag ttgaaatgat atgcccagat ttttgttttt ccatgattgg
    11281 aagtacggcg gaaattccat ttaacacacc catgatgttg atatcaagca tattttgcca
    11341 ttcatcacgg tgaccttcaa ctaatggagc ggttggcatg attcctgcat tattgtacaa
    11401 tacatcgatt cgaccgaact tttccatcgc taaatcgata actgcttgga cttgtgcaaa
    11461 atctcttaca tctgctgttt gaatatatag ctcagcttct ggtaaagatt cttttattgc
    11521 ttttaggcga tcttctcggc gtgcagctat aactagttta gccccttttt ctgctaatag
    11581 cttcgttgtt gcttcaccga ttccgcttga agcgcccatg atgacaatca ctttttctga
    11641 taaatcattc attctattct cctcctgttt tgaaaaatct cttgcttata ctcactatct
    11701 cttatttcat cttactgttc aaataatccg ttcgacaggt ttgacgattt tggcagggat
    11761 tcctgcaacg atggtattgt ctgggacatc tttcgtaaca gttgcattcg ctgcaacaat
    11821 ggcattctcg ccaatcgtta cgcctggcag aatagttgct cctgctccga tccaagcatt
    11881 tttcttgatg tggattggct ttactgacaa gcctcttcgt tcttttggat cggttagatg
    11941 gttcaccgtg atgaggttga cacgaggacc aatcaatact gaatcttcta aacagatgcc
    12001 acctaagtca acgaacatca cttgacgatt gataaagaca tttttcccta tactaatatg
    12061 tttgccgaaa tctgtataaa aaggcagcag aacagtcacc gtatcatcta ctttgtcact
    12121 aatgatattt tctagccgtt tgcggatatc tgctggttca tggtacccag tattcagcgc
    12181 tgctaaaggc tcttcgtttt cagcttggat ctgatggatc acttcaaaga gcggatccgt
    12241 tactcgaatc tctttattga cgatttgttt ttcgatgagg cttgtcattt tgctccctcc
    12301 ttttatcctt actttataac ggacggctta tcatgtctaa tacttataaa acatacttaa
    12361 ctattccttt taactatact tagtggtatg cttttttaaa aacaggaggg aaaaaatgga
    12421 tattcgtata ctgacgtatt ttttagcagt agctagagaa aaaaatatca gccgagcagc
    12481 aaaatctctg catatcacgc aacctactct ctcaaaacaa ctgaaagatt tagaagaaga
    12541 acttggtgtg acacttttca ctcggggctc ccgagagata cagttgacgg attctggtcg
    12601 atatctttat tcaaaaggaa aagaaatctt gtcgttggta gaaaaaacgg cgaacaattt
    12661 aacaaatgac gcaatcatct ctggagaaat ctacattggc ggaggcgaaa ctaaagcaat
    12721 ctctttcatt tctgatagcc ttcattcgtt gatcaaggcg catcctgata tccagtttca
    12781 tttatatagc gggaatgcag atgatatcat agacaaactg gatagcggat tacttgattt
    12841 tggactcgta atcgaaccga caaacaaaca aaaataccag tcatttcgac tgccagccca
    12901 agatcgttgg ggacttttga tacatcgaaa tcatccttta gcaaagcaaa ccgtcatcca
    12961 tccgcaggaa ctgaaaactg ttcctttgat catttcccgg caaacgtcag tggacagtca
    13021 actagctgaa tggctaggtt tcagcataga tcagttatcg atcgtcggaa catataactt
    13081 attgtacaat gcttctttga tggtcgataa cgggactttt ggtgcattag ctctagatgg
    13141 gatcatcaat acttatggga cggaaaaaat attcatccca ctcgatccgc cattacaagc
    13201 ttcactgaat ctcatttgga aaaaagacca gcctctttct cctgctgctc gtaaattttt
    13261 agatgtccta acggagaaat acagttaagt agagtttttt tccttcgctt tcagcttttt
    13321 aacaacgaat aagataagca aaagatccaa cgattaaata acataagttt cttaatttat
    13381 ttcttccttt tatttctgat aattccagta aattactata attataaaaa aagaattgac
    13441 aaaacataac tgtctatata aaattgatta cgttaacaat aattcgtttc atgtgactag
    13501 atcatactag gcatgaaaaa tctctgagga acatggtttc cctaggaggt ttttcgtgtc
    13561 tatttttgtt tggccgcaat caactggtct agcaaacgtg aaaaccaaat cttcaaaaag
    13621 ggtgcgcgca tgaaaatcaa aaagatcttt aatcaaaatg cagtattggt agatgacggt
    13681 ggacaggaaa aagtagctat tggaaaaggg attggatttg acagaaaaag aaatgatttg
    13741 atttttgatc gtgatgtcga acggatattt gtcatggaac cagaaggtca aatcaagttg
    13801 caaaatttac ttaatcagat tgatgaacgc tttttatttg cagcagaaac gatcattgat
    13861 catgcggaaa ctgttttgat ggaaaagttg aatgaacatg tattgatcgc tttgaccgac
    13921 cacattgctt tttctgcgga gaacattaat aacggtatcg tcatccgcaa caaactttta
    13981 agagaaatcg aagtgcttta cagtgatgaa ttcagtattg ctcaatgggc agtagagtat
    14041 ctgacaaaag agcttgggat tccatatact tatgacgaag caggatatat cgcaatccat
    14101 attcacagcg gacgaagcgg tcggaacaat aaccatcgca gtatccgtga agtgacgatt
    14161 gtatctgaca tcatccattt agtggaatca gaattggaaa cagatatcca ttcagaacca
    14221 ttttcactga attattcaag actggtgaat catttacgac tacttctaca acgaacccat
    14281 gcgcaacaat atgctgtttt agacacggaa atcgtagaaa tggtcaaacg aaaataccca
    14341 gaaagctata agatttctaa aaaaatccgt gtgttgctga ccaaagaata ccagctcgcg
    14401 atcacgaaag aagaactggg ttacttggcc atccatatcg agcgtttaag aagcgcaatc
    14461 gtacaaacaa atgttaacaa tcatgaggag gaaaaaaatt gaaagcatat ctacaacgaa
    14521 tgggacgttc ccttcaactt ccagttgcgg tcttacctgc tgctgcttta ctagtaggga
    14581 tcggaaactg gtgggcatct tatagtaacg acattgtcgc tcatttttta caagctggcg
    14641 gtaacgcagt tttaggtcaa ttacctttgc tgtttgccgt tgggttagca ctagggatgt
    14701 cagtggacaa atcaggtgct gctgccttgg caggtttggt cgcatttgaa gttccagtaa
    14761 atgttttaaa aactgattca gtagctactt tattgaatat caaaccagaa tcagttgatc
    14821 catcttttgc tcagatcagt aacgtattta ttggtattat tgccggattg attgcggcag
    14881 ctctttataa tcgtttccac gaagcaaaat taccgatggc tttatctttc tttagcggca
    14941 agcgtctagt gccaatcttg gctgcctttg tcatgttgct gatcagtgca gtgctactgc
    15001 tcgtatggcc tccggtttac tctgctttag tttcttttgc taaattcatt ttgagtttag
    15061 gctggggtgg tgcaggtctt tatggcttct tcaaccgttt actgatccct acaggattgc
    15121 atcaagcaat gaactccgtg ttctggtttg acgtagcagg aatcaatgat attggtaaat
    15181 ttttggcttc tgaaggaaca aaaggcgtaa caggaatgta tcaagctgga tttttcccaa
    15241 tcatgatgtt cgggcttcca gcaggagcat atgctattta cagaaatgca cgtccagaaa
    15301 acaaagcaaa aacagcttcc ttgatgctag cagcagcttt tgcttcattc tttactggtg
    15361 tgacagaacc acttgaattt tcatttatgt tcgttgcttg gccattatat gtcttgcatg
    15421 caattttcac tgggatttct ttagcagtga gtgcattctt ccattggaca gcaggatttg
    15481 cctttagtgc cggatttgtc gattacttcc tatctttgaa aaatccgatt gcgaatcagc
    15541 cattgatgtt gatcgtccaa ggattagtaa cagcagtgat ttactacttt ggctttaact
    15601 ttgctatcaa aaaattccat ctgatgactc ctggccgcga ggaagcagat ctttcagatg
    15661 acgatactgc aacgactaat tcagacaata aatatgcggc acaagcaagc aaaatctacg
    15721 ctgcattagg cggagccgac aatgtaactt cgatcgataa ctgtactaca cgccttcgtt
    15781 tgcaagtcaa agatacaggc ctgatcgatc aaaataaaat caaagccact ggcgtacctg
    15841 gtatgaagat catcgacgga aaaaatgcgc aagtcatcgt aggtacagaa gtacaattcg
    15901 ttgcagatga gatggcaaaa ctacatggtg gtgctgcagc acgacctgca caaacaaaca
    15961 ccgtggttaa aacagaaaca tttgccggtg aaacgatcga acaagatatt tacgctatcg
    16021 caaatgggaa actgattcca atcactgaag tttcagatga tgtattcgcg gaaaaaatga
    16081 tgggtgacgg ctatgctgta ttaccagaaa atggagaaat cttctctcca atcgctggta
    16141 cgatcacaaa cattttccca acgaaacatg ctgtcggaat ccaaacagat gctggtatcg
    16201 aagtcttgct tcatatgggc atcaacactg ttgacttaaa aggcgaacca ttcactttat
    16261 atgtagaaga aggtcaaaaa gtcgcaagag gtcaattgat tgctttagtt gatcttgccg
    16321 ctattcaatc tgcaggcaaa aacacggata tggtcgttgt attcacaaat ggcgacaaag
    16381 tccaaagctt agaaatcgaa cccgcacgtg atgtaaaagc aaatgataaa atcggctctg
    16441 tttccaacaa agcctgagcc atcgtcttcc ccagactttt ttatcgataa acaaacagga
    16501 gctgagacaa aaatcttgtc tcagctcctt tttccgaata aaaacggcgt tctcctgcca
    16561 actccgcggt aataagtcca gctaaacgaa acatatgaag agctattttt tatttgactc
    16621 ttcttattac ttgatgcaga acagcttttt cacaaaattt ttcttcatac tcaaaactaa
    16681 tcggcttttt cacaacctct ttatacatta ttcctgatcc aatatttctt ttaatgctgc
    16741 ttcaagagaa gttaatggtt ttcccaatac tttttctaaa tcatcagagg aaatagctaa
    16801 ctgatccttt ttaatatcat gttggatcgc taaaaacatg tcagctgctt cttgagggaa
    16861 tccggcttct tttagatttt cgacaaacgc tgcatcactt gcttcaataa tttctaactc
    16921 tttacctgtc gcacgctcta atgccttggc taattcttca tagtcagtta gattgccgga
    16981 taattctaag atttctggag agtcactttc tactagtact tttgctgcag cttctgcata
    17041 ttcacgtttc aatgcccaac ctgtttttcc atttcctgca gcataaacga attgaccagt
    17101 ttttaaagcc tgcccaatga taggtaattc attctctaca taccaattat tccgtaaaaa
    17161 tgtatgggaa atacctgaat ccttaatcat tttttcagtg aattggtgat ctggcgctaa
    17221 tacactgatc gagtgatcgg catctgcaaa acttgtataa gcgatataag ataccccagc
    17281 tgcttgtgct gccttcacta cattcttatg ttcggcttga cgatttcctg gaacgccaga
    17341 gacaaaaagc aatcgatcta ttcctttcaa cgcttctttc attgagtcta aatcatcata
    17401 atcaccaata cgtatattaa atccagcttc tttcagtgct tctccttttt cttcactacg
    17461 tactagtaca tagatttcat tttgtggaac catctttttt aagaattcca gcgcataacc
    17521 accaaaacct ccagttgctc ctgttactaa ataatgcata tttgccactc cctattcttt
    17581 ttatttgtta agatttacag ctgtacattt ataaattaca cctttatcat aaagagtgtg
    17641 gtaagataag tcaagcaaaa aaaatgaaag gatgacaact gatgaagtat tctctgcaat
    17701 ttagtgatgc aatccatgta cttgcctata ttgaaatgtt tcaagatacc cgatcacttt
    17761 ctagtgagat gattgccagt agtatcgaaa caaatgcagc aaatgtacgt aaaatcatga
    17821 gtcagctcaa aaaatccggt ttgatcttta caaaaaccgg aaaaccgcag ccttcccttg
    17881 ccaaaagtcc agatcagatt tctttactag atgtctatcg cagcatcgaa ggtaatacac
    17941 agcttatcca agtcgatcca aaaacaaatc caaattgcgt cgttggtgcg aatatccaag
    18001 aagctttaga agaaagctac gctcggctgc agaaaaaggc agaagaagaa atggctaaga
    18061 tcacacttga tagtctgata cataaaatag ccgttttgga aaaagaaaaa agaccagaaa
    18121 acacaggcct cgtagagaga tttttataat tctctctact gtgcctgcat ttttctgatc
    18181 ggaatcgtct acataaattc ttttattctc cgggggacaa aagccttgtc atgccccttt
    18241 ttcctctcta atgctcaggt caaagcgctg aagtcatgac gtcttgataa acggtgttca
    18301 agtagctgac cctcggcatt agttctgaaa aatgcaaaat atggaaagct atttcccatt
    18361 tttcctctct aatgctcagg tcaaagcgct actttcacga cctctatatt atcatggttt
    18421 attgactacc ggtatccaga tttctcccat atatttcccg ttggtaactc ccatttcgac
    18481 tacagcattt ggacccccaa cataggcgta atcttctact tctcttaaaa catgcccaaa
    18541 ggccgtattc gtcaaatcat ttcttaattc ttcaggcgat tctgctaaag cgcttacaac
    18601 aagatacgtt ccttttggga atgggatgat tcgcgtagtg tttggaacat cctgactcgt
    18661 ttgaacaccg acatagtaca tcattttccc gttatagggt tcgttgactg taaagaaata
    18721 atgattttca gcagcttgtt tcaatgcatc tattgttcca ttaccgataa ctttttgctc
    18781 aaatgcttgt ttctctgcag ccaaaccgac aaaatccgta ttgctactct tcaattccac
    18841 accaataccc gtcaccgtaa aatctggttt ttcttcgatc ctatactttg ccatttctcc
    18901 caccctttct attatattaa gttcatctta cataaaatta aagggaaatg acacgattac
    18961 gctctttttt ctagggatat ttttattttt taactatttt tttgctttca ctgcaatcca
    19021 aatctcactg taaacattac tgaaatcctc tccccatttt gtaaaagaga tctcgggagc
    19081 ttcgactaac ccataatctg aagaaggaag ccattctgca tagattttcc cccaagtatc
    19141 ttgtaaagtt tggggaaatg gccctttatt aggaaaaatg gcccaagtgt gttcttctat
    19201 agcaagcatt tctaaatcag cgtacggatt ttcttttgtc gtagcaaagc caatcatgtg
    19261 catcaaactg cccttttctt ccaagcggtc tccatcaaat ccataagaaa cgttgattac
    19321 ttgatttgga tataaatctc ctaacttatg catctcttcc ctttgagtct ccgtgatcgt
    19381 ctgcgctaac ttttgtattt cttgattgac tccttcaaat ttgacaggaa cttttttcgc
    19441 cacacctgcc acataaaact gttctttctt ttcgatacga aattccatcg attttcctcc
    19501 tctgacatca ataaaaaatg tcaagcgtgg aaaagatttt tgtatgccgt atctgctgat
    19561 ttctgaaggc agatatcctg accaatcacg aaaagctctt gaaaaacctt cgactgtttc
    19621 atatccatat ctaaacgccg tttctgtcac tcttgatcca tctagaagat cgcgattagc
    19681 caaagccaat ctacggtttt tgatatagtc cattagcgac atccctgcaa taaacgtaaa
    19741 gatgcgtttt aattgatatt cagagattcc tgtattttcg gctattattt tataggaaag
    19801 tccttctgtc aaatgttctt cgatgtaatc gatcaattgg ttcagatctt taagcatatt
    19861 tatcttcctc cttgattgcc tttttatcat attatcaaag aaagtcaatt acttgatgaa
    19921 tcaggaacca atttagtcag atgtagaaaa tgttgtatgg atctaaagaa aattctcaag
    19981 cagcgtttcg taacggataa ttggtattat ctgcctatct atgttttacc tttagaaaaa
    20041 taaattttgg ggaagacaga ttctaagtaa acaaagcggt aaaaatatct tttattccct
    20101 tagttaatcc gcttactacc tactgtacaa agcaaattgt tgttcaaact gctgatcaga
    20161 acgctgcttg gatttttctt t
//
LOCUS       DARPZF010000047        19195 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.049, whole genome shotgun sequence.
ACCESSION   DARPZF010000047 DARPZF010000000
VERSION     DARPZF010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.049"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..1416)
                     /gene="nhaC"
                     /locus_tag="SLE65_002118"
     CDS             complement(<1..1416)
                     /gene="nhaC"
                     /locus_tag="SLE65_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HEI8449391.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGEIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(1819..3042)
                     /locus_tag="SLE65_002119"
     CDS             complement(1819..3042)
                     /locus_tag="SLE65_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HEI8449392.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(3073..3912)
                     /locus_tag="SLE65_002120"
     CDS             complement(3073..3912)
                     /locus_tag="SLE65_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEI8449393.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(3929..4609)
                     /locus_tag="SLE65_002121"
     CDS             complement(3929..4609)
                     /locus_tag="SLE65_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8449394.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(4611..5684)
                     /locus_tag="SLE65_002122"
     CDS             complement(4611..5684)
                     /locus_tag="SLE65_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8449395.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(5740..5978)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(6021..6254)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(6331..7002)
                     /locus_tag="SLE65_002123"
     CDS             complement(6331..7002)
                     /locus_tag="SLE65_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEI8449396.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(7089..9767)
                     /gene="mgtA"
                     /locus_tag="SLE65_002124"
     CDS             complement(7089..9767)
                     /gene="mgtA"
                     /locus_tag="SLE65_002124"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HEI8449397.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            10426..10863
                     /gene="ndk"
                     /locus_tag="SLE65_002125"
     CDS             10426..10863
                     /gene="ndk"
                     /locus_tag="SLE65_002125"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEI8449398.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(10885..11751)
                     /locus_tag="SLE65_002126"
     CDS             complement(10885..11751)
                     /locus_tag="SLE65_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEI8449399.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(11911..14004)
                     /locus_tag="SLE65_002127"
     CDS             complement(11911..14004)
                     /locus_tag="SLE65_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEI8449400.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(14753..15376)
                     /locus_tag="SLE65_002128"
     CDS             complement(14753..15376)
                     /locus_tag="SLE65_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449401.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(15535..16932)
                     /locus_tag="SLE65_002129"
     CDS             complement(15535..16932)
                     /locus_tag="SLE65_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEI8449402.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(16964..17935)
                     /locus_tag="SLE65_002130"
     CDS             complement(16964..17935)
                     /locus_tag="SLE65_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8449403.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            18309..18734
                     /locus_tag="SLE65_002131"
     CDS             18309..18734
                     /locus_tag="SLE65_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449404.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
BASE COUNT         5550 a         4067 c         3232 g         6346 t
ORIGIN      
        1 ttgttctaat tgcgctgtct tgcttactgc ttcttgcggt ttcacaaatt tttttgagat
       61 tccccaacct gtgaaggcac tgaccatcga aaacacagga gaaagcaaac tgaaaaatac
      121 gaatggcaag taagtgagtg taggaatacc aaatgtactt gctacgaaac ttccggcaat
      181 tccccaaggc actaagtagt tgattactgt tccaccatct tctagcgttc tacctaatac
      241 agttggatca aatcctgctt tttcataagt ttctttaaat gcattaccag gcagaataac
      301 agataggaat tgttcaccaa taaaaatatt tactccgata cttgtcatca atgttgtaaa
      361 aatcaaattt ggtgtgttcg tcatctttct tgatactcgt tccatcacgg ttgagatcaa
      421 gccaaattcg atcaacaatc cacctaatga caaagttaga ataatcaatg acacagtagg
      481 catcatactt tcgatttctc cgcggctaag cagtgaatcg atttgttggt ttccagtatt
      541 tgaaacaaac cctgattcga tgaccccagc caacttcgtt aaggaagttt gtgggttttg
      601 aataaaaatc attcctactg ctacagcgat attcaacaaa atcgttaaaa ttgccggcac
      661 ctttttccat gcacacagta acattaaaaa taaaggaatc agtgaccaga ttgaaatagt
      721 aaagtttgct tctagaacat cagtcacttc acgaatagat gaaagacttg cggctttact
      781 tgtgtgtcct aaaatcatga ataaaaagaa agaaacaaca aatgccggga cagttgacca
      841 catcatatgc ttgatgtgtt tgaacaaatc ggcatcaaca atagctgctg ctagatttgt
      901 tgattcggat aatggagaca tcttatctcc aaaaacggca cctgaaacaa tagctccaac
      961 aaccagcgct ggatttaagc ctagtgttgt cccaataccg aaaaatgcaa tcccaatcgt
     1021 tgacataaca gtaaaggcac tccctacagc gctacctacg attgcacaca caacaaatac
     1081 agaagggaca aaccactgga cactgatcaa tttgaaccca atgaccatta gagttggaat
     1141 gatccctgct tgtatccata cagcaatcaa tgaaccgact aaaataaaaa taaagattgg
     1201 gatgattcct ggtttgatgc cattgatgat tccttcgtgc agccaatctg tcgggtatct
     1261 ttttatcact gcatacaaca tgaccattcc gatcgctgct aagatcgtga tattaggtga
     1321 gacctttaat ccgacaacgc caatcgcaat gcctaaaaca ataaccatta atacaagtgt
     1381 tgcttctaaa aaacttggtg ttcctttttt tcccatgata atctctcctt ttttagttgt
     1441 tcttatgttc taaaaaagtt aagatatcgg attactccgc cgcaattcat ccgcgattcc
     1501 tcctttataa aaataaaaag acctgtttta aactaaggac gaatgactcc gcggtaccac
     1561 cttaattaaa aacagatctg tttttcactt tcaaactttt attcaaatgt atggactttc
     1621 catgtaattc gtcaattagg cttgatcggt tcacagcgac caccgacttt ctgaacaaaa
     1681 cacctaaccg ctactgcgtg aaaagttgac ttgtacgaag tttaccttcc ataagatcat
     1741 ttgtcaatga aaaagaaaat attttttcat ttttctgaaa attattttta taactttcac
     1801 acacaagttt attttttact agaaagtagc gccctcttgt ttttttcttg ctactatttc
     1861 ttgatgttct tgcttgattc tttctaatag ctttggctct ttcaacagat caagagctgt
     1921 attggcgagt agttctgctg caatcgcaat agaagcaagg cctttgtcac ttttagcagc
     1981 agctttgaat tcttctgtgt gtccggcaat atatgtctca gagattgcta ccgtaggctg
     2041 gattgttggt atgacttggc tgacatttcc tacatcagaa gaaccgagac ttgttctttg
     2101 ttccgtttct atttcttcat ctggaacacc tgcttctttt gcatgctgga agaataagtc
     2161 atcaaaagaa ggagtaacga tgacatcatc aactgcattt tggaacaatc caaactcaaa
     2221 agtcgtgccc gtacttatcg cagcacctcg tacgatattt tccacttttt catatacttt
     2281 atctaatgtt tgccgatttc ctgcacgtaa atagaaacgt ccagcagcgt aatctggaat
     2341 gacgttggca gctactcctc cgtctgtaat gatcccatgg atattgacat cttttggcaa
     2401 ttgcaagcgt agagcgttga ttccattaaa cacttggatc aatgcttcca aagcatttac
     2461 tcctttttca ggtgctgctg ctgcatggga agcgacaccg taaaatttga tgtcgactgg
     2521 atcattcgct aaagattctg tcgttttccc ataacgaaaa gctggatgga cgcataacgc
     2581 tacatcgaca tcctcaaaaa aaccttctcg aacaaagctg cctttagctg atccgttctc
     2641 gcccccttct tcccctgggg tgccatatac acggatttct ccaccagttt catcaatgaa
     2701 ttgcttcact atgctggcgg ctaatacgga gtaagtacca aacaaattat gcccgcatgc
     2761 atgaccaata cctggtaaag catcgaattc tgccaaaaag gcaattgtgg gaccgggttt
     2821 attggaaata taacgtgcat caaaggctgt tcggtgtcca gctacttctt tttctaccca
     2881 aaacctttct ttttctaatt gtttaatcaa cgctgctgag gaataaaact catagttact
     2941 tacttcagga tgttcgtgga tatctagagc aagtgcttga tattctggta aacgatattg
     3001 gattagatcc ttcaattggt ttgttgagat tgttgttgtc ataaaaaatt cctcctatgc
     3061 tagtcatttt tcttattttc tcccgaatgt ttcccatgca ggcacgcttg atccttttga
     3121 tgttttctcg attactttga ctgtgtcttc tgtttgataa gcgtctacta ttttttgata
     3181 cgttttattg ttttcatctt cttttcttgc aacgatgata ttcacataag gacgtgcatg
     3241 gtcatccact ggttctaaga agatggcatc agaagcagga ttaaatccag catctacagc
     3301 tacaccgcta ttgatcactg aaatgtctac atctgacaaa gcacgtgctg tttgggaagc
     3361 atctaattca gaaatgtcta gattttttct attctcggta atatcagaaa cagtgggcgc
     3421 ttgtcctttt gccttatcca ctttgatcaa tccagcagtt tgcaataaca gaagagctct
     3481 gccgccattt gtaacatcat tagggattgc tacttttgct ccgtctttga tatcagctac
     3541 atccttcaaa gtgttagaat aaattcccag cggtgcattg acagtatttc cgatcgatac
     3601 taaatcagtt ccgtgttctt tattgtaatt gtctaaaaag aattgatgtt ggaaagaatt
     3661 caaatcaatc gatccatctg ctaaagccac atttggttga ttgtaatctg taaatttcac
     3721 gtattccaaa ttaatgttct cctttttcaa acggtctttc acgttgtccc atacatctgt
     3781 atcttctcca ataatcccta gttttacgat agtttctttt ttgtcagttg tatctgcttt
     3841 tccttggcta caccctgcca accaaataat tgctacaaat gtaatgacta caaaacgaat
     3901 aatttttttc attttttctc ctccactttc aatgtgtaat ttttttaatc agttgattac
     3961 tgataaattg acttaaaaaa actaagatta gaatcaataa tgtagccaca atcgttacat
     4021 ctgtttggaa tcgattatac cctctcgata tagcaagatt ccctaatccg cctgcaccta
     4081 ctgctccagc catggtagtc agtccgatca cgttgatgat agtcaacgcc gagacccgaa
     4141 tgataccagg caaaccttct aacaaataca cacgtaaaat gataccgatt ggactggttc
     4201 ccatcgcttc tgccgcttcg atcaccccag gatcaacttc tagcagtgcg ttctcgattt
     4261 gacgagcaaa aaacggaaca actccaaaaa tcaatggcac taaagctgct ttcgcaccaa
     4321 tcgtcgttcc aactaagaaa cgagtagtca atgctaaaag agaaagcaag ataatgaaag
     4381 ggatggaacg aatgatattg atcagcttat caagtatttc aaatagcaga cggttagcta
     4441 gtaatccatt agggcgtgtc actactaacg tcacacctaa gatgattcca atcatcccgc
     4501 caatgaatgc tgtccaaaaa gacatatata gtgtttgctt cgtcgcttcg acaaattcat
     4561 ccggaatcaa ataaacattg ggcaaatatg ttttaaagaa atcagtcatt ttatcttcct
     4621 ccttcgatca ctttgatacg actatctaaa tcgttttttt gtaaaatatt tatttttaca
     4681 ccagatttga tcaaataatc caatgctttt ttccgctgtt tggtttctcc agctaaagta
     4741 acgatcaaac tccctaacgg cgtttcttgt aataactcta cattgccata taaaatattc
     4801 gctgttactt gatatttgct gtacagatga gcgattagag gttcgttcgt ctgatttcca
     4861 atataactta attccaccag ccatttattg gcgatctgat cggcaaaagc agaatgggca
     4921 atgatcgttt ctaatgcttg gtcaagatga gtagctgttc gaataaaatc tttggtcaat
     4981 tcttcttcag gattgctgaa gatctggatg ctgctacctt tttcaacgat tcttccatct
     5041 tccataaccg ctaccttgtt gcagatttct ttgacaactt gcatctcatg agtgatcagg
     5101 acgattgtta aacctaactg gcgattcaat ttttttaaca atgcaaggat ctgaagggtc
     5161 gttttcggat caagtgcact ggttgcttca tcacataata ataccttagg ttcattcgcc
     5221 aaagctcgtg cgattgctac tcgttgtttt tgtccccccg acagttgttt aggataagca
     5281 gatgcttttt cttccaaacc gacaagttcc agtagttcat tcactttttg acgacgttcc
     5341 tgtttcgatt ttccagaata ctttaaagaa aaatcaacgt tgtcaaaaat agttcggctt
     5401 tccattagat tgaaatgctg aaagatcata ccgatggcct ttctttcttt tcgcaattct
     5461 ttgggagaga gctgactcag attcgtctga ttgacaatga cttctcctgc tgttggtttc
     5521 tgcagcaaat tcatcacacg aactaacgta cttttccctg cacctgagta accgacgatt
     5581 ccataaacat cgcctttttc aatcgttaaa tctacagaat ctactgcctg tatctctttt
     5641 tctttttgtt tgaaacatac agaaacatct cgcaattcaa tcattaaaat tcctccttat
     5701 ctaaaaaaag cgtcctcaag aaaatgaaaa tgtcattttc ttgaggacgc ttttttgcgt
     5761 gttaccacct catgttcaag ctgtgttcac acacaactcc tcttcaagta cgatcatact
     5821 ctagcaagat atcggtcgca gccgtcatcg ccttacatct atgctcggga tgaattgctc
     5881 gatggccatt ttccaatagt cgttccttgc ttcttctcag ctaccgaagc tctctgtcaa
     5941 aggttcttct atcgtactta ccatttcaat gcaaataata ttcaaaaaaa aagtcctttt
     6001 actaacataa actatgtcag taaaaggacg acgtatcgcg gtaccacctt ttttcggaag
     6061 tttccttccc tcaagcccaa catctcaaaa agagagattg gcgttcgttt taacggtcga
     6121 acagttccga atttgcctac ttatcgacaa attattctcc aaggccattt tcagcttttc
     6181 ttacttgact cttctcacca gccagagcct ctctgcaaag tttccaaact tactttcctt
     6241 ttcaacgaaa tcgatatttt gttgttggga ttaatctaca tgaggaaaac tgaaaagtca
     6301 agtacgaaat tcaaattatt ttttctatat ttatttttct gtttttttat ttaacatttc
     6361 aataacagtt cgaagatctt ttccttccgc aagaagtttc aatttttcct tttcttcgac
     6421 ggtataattt cggacaaaac tggaatcagg tatcaaaaca acgcctaatc ctgctcgtga
     6481 agcagctgtt gctcctacta aagaatcttc cactgcaaag gctgaactag cttctaatcc
     6541 tgttcgttcc aaagctgtca gataaggaat cggtgaaggc ttgttctccg acacttcgtc
     6601 tccgaatgta aacgtgtcca agtaatcagc taatttaaag tgatccaaga tatctgttgc
     6661 tcttttcgta acagtggtcg tagcaatgcc tagtttcata tgacgttctt ttaagtctgc
     6721 caatatttct tttgcatatg gttttaagtg gatggctccg cttgtcagct gttgataaaa
     6781 atattcttca cgcttcgctc ggacttcctg tactttttca gggctacctg ctgctttcac
     6841 taaaatatca aaactttgtt tccagttttt tccgccccaa gcgtcaacga tttcttttgg
     6901 gatatggata tcaaattgct gaaatcccca aagccagcca tcacgatacg ttttttctgt
     6961 gtcaactaac aaaccatcta aatcaaatat tgcacctttc atctatacat taatcctttc
     7021 caaaacaata cacatagttt agcacgactg gtccaaaaag aacagaagca aagaaccagc
     7081 cttctcgttt ataagagttc ttggaatcga cggatataga ttttcttcac agctgtcaca
     7141 agcgccagat aagcgatgac tgtagcaaat aaccataacc agtaattgcc aggaagtggc
     7201 atcaagccta attcagcacc aaaacttgta aaaggaagga cagaaccgac aataattcct
     7261 aatgtagtga taacaaacat ggcaaatgtt gcgttgcttt ggataaatgg tactttcggt
     7321 gtacgcagtg catggagcac taaggtttgt gtccatagtg attcgacaaa ccatcctgca
     7381 tggaataatg cgatgaaaat cactcgctgt gaactatcca atgtatggaa acttccgccc
     7441 actacagcag gacaaataac aaaatacatc aacaagtaag tagtaatatc aaatatcgaa
     7501 cttgttggac caaagtaaac catgaattcc ccaatactag atgcattcca tttttttggc
     7561 tcgtccaaat attctttatc catccgatcc catggcaagg aaatgcagga aacatcatag
     7621 atcagattca aaaacaaaag ttgtaaaggc agcattggta aaaatggcag gaacgtactt
     7681 gcaatcagca cggaaaacat attgccaaaa ttagaacttg ctgtagcctt gatatatttc
     7741 atgatattcc caaaagtttc tcgtccagaa agaaggcctc tttccaaaat cgtcaaatct
     7801 ttttctaaaa ggatcacgtc tgcagattct ttcgcaatat ccacagctgt atctacagaa
     7861 ataccgatat cagccacttt cattgcagga gcgtcattga taccatctcc taaaaatccg
     7921 acagtatgac catttttacg taaagctgtc gtcaaacgtg ctttttgctg aggattcaat
     7981 tttacgaata cttcatggtc ttcagctact tgtgctaatt catgatcact catttccgag
     8041 attttctcac cggtaaccaa ttcattgatc tctagaccta cttgacggca cactgaacgt
     8101 gtaactaatt cgttgtcccc agtcagaact tttacagcta caccatgttc tttcagagct
     8161 ttcaacgctt gtttcgttgt ttcttttggt ggatcaagga aagcaagata accaatcaaa
     8221 accatgtctg actcatcttt gactgaaaat tctccaacga cgcttggatt ggtcttttgt
     8281 gcgacaccaa tcactcgtaa gccatcttca ttaagtgact gtacttttgc aagtacggct
     8341 tcttttcgtt cttttgttaa tggtgtaaca gtaccgccaa gatcaataaa tttagaaatg
     8401 ttcagcattt cttcaatcgc gccttttgtg atcatttgtg ttttaccagc tggatcagca
     8461 accacaacac tcatacgacg acgttcaaaa tcaaaaggaa tttcatccac tttttgataa
     8521 ttgatcttat ctgtatctaa agtttctgtt gcttcatcaa tgatagccac atctaacaaa
     8581 tttttcagcc ctgtttgata gtagctattt agatacgcat ggcgcaaaac acgatcatct
     8641 tcatttcctt cacaatccat atgatattca agaatgattt tatcttgtgt caatgtcccc
     8701 gttttatccg tacataacac atcgattgca ccaaagttct ggatggcatt caaatttttg
     8761 atcactgttc cttttttggc catcacactt gctcctttga ccaaattcgt cgtaacgatc
     8821 attggaagca tttcaggtgt tagaccaact gctacagata gtccaaaaag aaaagcttct
     8881 agccaatccc cttttgtaag cccattgatg acgataactg ctggagccat caatgacata
     8941 aatttgatca gtagcatgga tgttttatgg atgcctaatt caaagcttga ttgaattggt
     9001 ttttcagata gcgtttctgc tacatgacca aatagtgttt catttccaac agaaacaatg
     9061 attccttccg cacttccact gatgacatta cttcccataa agacaagatt ttcgtaactt
     9121 gtttcgcttt gctgatcgtc ttcacatact ttcgcatgct tttctactgg atagctttcc
     9181 cctgtcaatg ctgcttggga aatgaataaa tcctttgcgg acaataaacg catatccgct
     9241 ggtatcatat cccctgctga aagccgaaca agatctccac agacgatttc ttccatagga
     9301 atctctgtgt actttccatt acgttttaca gctgccgtta ctttcacaag tgatttcagt
     9361 ttttcagccg cttgattgga acgtacggac tgaatcaacg tcattgtccc gctgacgata
     9421 accatagtga agataatggc tacaccgaaa agatctttat ctccaggagc tgctaataca
     9481 tattccgtga tgaatgaaat aattcctaat gcgatcaaca ctaatgtaaa tggcgtgatg
     9541 tatgctttca atatttctac aatgaatggt gtttttttgc catatgaaat cgcattttca
     9601 ccgtaatttt ctcttgaacg ttcgatttgt tcttctgtca atccatttgc tgatgcatgg
     9661 aatagttcaa ataattcttg tttcgttttt ccagcaaaag ctgcatagat tttttgtgta
     9721 tctttctttt tttccatctc aatctctcct ttgtgtccaa aagacagctg ttctcgctgc
     9781 ttttggtctt tagctattca tcggatcgat agagaaaaaa ctgaaagggg ctgagaacag
     9841 atagataata gccctggcct ttcctctaga tccttgtttt tcgaatgact gtcatccatt
     9901 tgttctcatc tcctttacta agtaatttta attcatgact tccaatcatt tttcgaatag
     9961 ttatttttcc aattagacca cctccttttt atttttcacc gatggggatt tgcggcaaca
    10021 aaaaaacctc tcgccaaata ctcagcgaaa ggtttgaaaa agcatattaa aaaaagcttc
    10081 tcagatctca tcgttgagtt ttgacactgt acaacgtaaa aagcagatac ctgcttttag
    10141 ctaccttatg aaaagcctta tctcgacaat tcctgttcta cccattggcg tctctcgacg
    10201 tttttgggca gtagcctatg tttgtatagg agcctcacct aacaaatctt attcggtttt
    10261 ccttcgttaa tataacaact aaaaaagagg atgtcaaatc aattttccat gtttttcata
    10321 ctttttttaa aatacacacg ttatattcct gtctcacgcg gttttatttg tctcattttc
    10381 cacctcccgc tataatagaa atatagtagg aaacgaggtg ctgttatgga aagaacactt
    10441 gttattatca agccagacgg cgtgagacgc catttagtcg gaagcatcat ccaacgtttt
    10501 gaagcaaagg gactggccat tgctgaaatg aagtttgaaa ctatgactcc tgaattagca
    10561 aaagaacatt atcagcactt gactgagcgc agtttttttg atgaactgat cgattacatg
    10621 acttccggtc ctgtcgttta tcttgtgctg gtcggcgagg aagtgatcga tatcgtccgt
    10681 aagatggttg gagcaacaaa agctgccgat gctgttccag gtacgatccg aggagactac
    10741 gcgctgccgg ggactgaaaa catcattcac gcttctgatt cccgtgatgc tgcggtaaaa
    10801 gagatcgccc gctttttccc gccattcgat ataaacaaac cgtctgaaaa agcggcgaag
    10861 tgatacaaat tctaaactgc tggtctagtt gctgggttca gcaatggcca gcagtttttt
    10921 ctctaaggac ctccgttgat tctttcctaa catatattcg agcactgtga agaattcttg
    10981 gtagtctttc gtcttttctt cccctaaagc agcagaaatc aatctttgat aataatctgc
    11041 catcaatgtt tcatagatca ctgtacttct ttctttatgt gctaagctcc gtttcatatc
    11101 ttcattcaca ctacgtgcct ttttcaaccg accattttct atataaaacg aagtcaggtt
    11161 cattaaaaaa gtaaagagat actgctcatg attgttcaac tgtgctaatc gtcgcattct
    11221 ttttttgatt ttcaaataat tgttctcaat gaaccgatca ctgaatatcc aaggaaaatc
    11281 agctagaata gatagttcaa attgaccata gtctggtatc tgcatcaagt attcttcaat
    11341 gattcggcat tcataacgta aaaattcaaa ttctgtctca gatacttctg ttttttcgac
    11401 catgtgaaga ttcaaaacca aataatacag atcttctgtt ttcttaaaat gcctacggtt
    11461 attgctgatc tctttataag gatcaaagct gtcttcttgt acccgatcta gcattcgtct
    11521 ttttttcttt aactttattg gttcatccag ctggtttcgc atccattcat attctgcaag
    11581 tgtcatgttc attcgctcta aaaatgatct caatgttaca aatgacattt ttttcactga
    11641 atttgtctca atcccgacta gagaagtctt aaaacagatt ccttccgcta attgggactg
    11701 tgtcaacttc ttgttgactc gaagtttctt gatcaattca ccatcataca taatagttct
    11761 cctttttaat ttaaattttt ccacattcaa taaatagata cgttaaaaag gaaaaataca
    11821 cgaaaaaaat aaaaaaatgt ttttttcata aaaaatacca accttcaagc attagaatgt
    11881 tgtctaacta ctgaaggttg gtttgattgt ttattgatta tttttttgct gttcaacgtc
    11941 tgttcttgtt actggatata agttggttgt tgttttatta ccattttttg aaaagacact
    12001 tgtcgaatgt tcgccttttt gcttttcgat tgcttcatta cgttccgctt catttttata
    12061 gtcatatttt ttcggatcaa tcgtctcaaa tccgtttggc acataaaacc gcaagagatt
    12121 ttcctgattc agcttatctg aaagacttaa cgcagtcttg actttttcct gatctttgga
    12181 gatttcctca tcgattcctg ctgctttcgt atcgatgatt tctcctgtct gattattgta
    12241 agcttttcct cctaggacgg tgtatttggg tgtcacaaag ttcccatttc gaaaagcaac
    12301 tacttgatca tgctgagaag ataataagtc tgtaccaaaa tgaagataat ctttatcatc
    12361 gattcccaat agatgtagta atgtcggcaa aacatcgatt tctccaccgt attcatgatt
    12421 gactgtccct ttagtataac caggcatatg gatcatcaat ggcactcgtt gcatctgtgc
    12481 gttgtcaaat tcatcccatg tatctggatc tttaccaaga gcgcttgcta aatctttatt
    12541 atctgtattc gagatcccaa aatgatcccc gtaaatcaca aagattgaat tttggtaaat
    12601 accagatttt ttcaaatacg taaaaaattg ttccaatgat tgatccagat aatgtgccgt
    12661 tcgaacataa ttatctactg tgctattgcc agtattcaaa gatggaaagt cgaaattctt
    12721 gtcatccgta taataaggcg tgtggttggt tacggaaaga aatttcgtgt aaaacggctg
    12781 ttgtagatgc tcaagatatt gggcagattc tctgaataaa tctttatcta atatcccata
    12841 acctaacgtt tcgtcggatt catcaaaata agatcgatca aagaaattgt cataacctaa
    12901 gtttttatat acatgatctc tattccaaaa actagctaca ttcccatgga aaacagcgct
    12961 tgtatagcct tgcttttgtc caaggatcgc tggtgcggct tgaaagacat tgtctgaccc
    13021 aagttctgtg aataatgagc cttgaggtaa accaaatgtg ccagtttcca acatattttc
    13081 agcatcactt gtctttccct gtcctacttc atgaaagaaa ttgtcaaagc tgatcgttgc
    13141 ttgattctgg aaaatactat ttaaaaacgg tgtgacttct tgtccgtcta ccttcatatt
    13201 aatcaaaaac tgctggaaac tttctaaatg gagaacgatc acatttttcc ctttagcgat
    13261 cccaaatgtt tcgggatttg gctctgcata atgtttcttt gtataatcta aaacttcatc
    13321 aatcccatta ctgcttgcat gcgcgcgaac actgctagtc attcctgttt tgattccgtc
    13381 ataaatagta tacgcatcga ttcctagata tttgacaata tatgaacggt caaatgttcg
    13441 ctgcagcaat tgtggacggt tggcttcgct cagcgctaga tttcctgaaa aaataagccc
    13501 tgaaagacag gtaacagcga tagccatcgg tttgccgaca gggttgcttt tgataggtat
    13561 tttcttgacc ttcaaccaaa ccagtagccc aatgaacaca gcgatatcca gccagtagat
    13621 gacatcatgg ggcttcatca aagaaaagga gcttcctgac aatccttgcg acactttcga
    13681 aaagcctaat acagatttga ctgtaatgaa atctgtgaat tcccgataaa aaataatatt
    13741 caagtacaac aaaagcgtat ttaaaatatc aatgatcaaa agaatagcta acgctggctt
    13801 tggcttttta atatacaaag aaaggccaaa aaacaataag gtagtcgcaa ttgggttgat
    13861 ccacaagata aagtactgga tcgtaccttc cacacctaat gaaaaatctg catagtaggc
    13921 aatgatcgtc ttcagccaga aaaagaaaac agctgtcaaa acgattgcta aacgattttg
    13981 gcacaatttt ttaagttgtg tcacgtatat cacttctctc tattcacatt ttttcttatt
    14041 ttgctcctga aaaatgaaaa tttcctaaaa aagttgttat cttaagattt ttttattctt
    14101 tctaaagatt attccgtcca cttttcacag cataaaaccg ctgcgatgta agcgattaaa
    14161 ctaatgaaga gataaaagtc ttgtggtgac cgcttcactc cacggtattc aaaagccagt
    14221 ttctcggtat tcgtacaaaa aaagaggctg tgacaaaatt cttgtcgcag ctccttattt
    14281 cttgatgcag gacagctttt tcacaacttc ttccttaaac ggtgttctcc tgccaactcc
    14341 tcggccacaa gtcacaatat ttataaaaca tgagaagctg ttttttgaaa ttgttccttg
    14401 tggctcagag ttaaacggca ggctcaagac ctcttgatac acggtgttca atcagctgac
    14461 cctcggtatt agattatgtc aggacgctaa ttttacaacc tcttggtaaa cggtgttcaa
    14521 aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa tataaggagc tattttttga
    14581 aattgctcct tgtggctcag agttaaacgg caggctcaag acctcttgat acacggtgtt
    14641 caatcagctg accttcggta ttagctcaaa aaacggcaaa atatgaggaa ctattttgcc
    14701 gtttgtttct ctaatactca ggtcaaaacg ctgatttcac aacctctgtt tttcattgtc
    14761 cataggattg atattgtcct tgtgatgact cattcgtaat aattgaggct tgattttctt
    14821 cacttcccgt tatcgtttgt ccactgccag aatctgaagg acttgttcct gtcgactcgt
    14881 ttttttgaga agagacagtt gttttcttga cttgttcatt tgtctttttc cattccgcta
    14941 aacgatcggc gaccactttt ttgtctactt tttcagaata agcggtgatc acttttccat
    15001 ttttcaaacg ggctactttg tcgccatcat gagtcaaaag caaaacggtc aaatgcttgt
    15061 ctttaaattg atattgtctg agagaaatcg cactaagtac gtcatcgata ttaataaatt
    15121 gattttcttc ttttcctttt ggcaaataaa tgtccaattc gcctttttcg taattggcag
    15181 ttattttata ctccgcccac caataagttg agaattcttt tttgaaatta tctactgatt
    15241 ctttgcttgc tacgattttt tctgtttctt tctgagcaag atctgctgtc atttttcctg
    15301 aaaatgctgc ggataaaata agcagtaaga aaaaaccgaa taaccaaaag agaagaaacg
    15361 gtcttttttt cctcatgctt tcctccactc ctatttaatt ttgactattc tattatatac
    15421 aaaaaatgaa atagaaagac aaaaaagttg aaaaagatcg taaataattg aacttctttt
    15481 tcacaaaatg gtaagaatgg agaatttcac gcatttgctc tcaactattc tttcttaagc
    15541 ctcaaatccg tttttatctg atacgtcttt gaaccaatga cccgattttt tgattgttct
    15601 ttttccatct tgtgctaagt ctactgaaat aaagccatat cgattcttat atgcattggt
    15661 ccacgaccag ttatccatac atgtccacat atgatagcct aaacaattgg caccttcttg
    15721 aatggcttga tggacatatt tcagatgaga ttggacaaat tcgatccgat aatcatcgtg
    15781 gatcatgcca tcttctttga taaatcgtgc ttcgttttct acacccatac cgttttcaga
    15841 aataaagcag tcgatatttc cataatgatc tcgtacattg atcaaaatat catagattcc
    15901 ttgttcatag atctcccatc cgcgataagg attcatttta cgaccaggca tttcataatt
    15961 gtcgaaataa tcctcaggca ttggaccgtt tttagtatcg attggtgttt cttttgcttt
    16021 tacccggcgt ggctggtaat aattgatacc taaaagatct actgtatttt ctttgataac
    16081 cgtcaaatcc tctgcatgga tcacaggcat gagatcaagt tcttttacta tctcaatcaa
    16141 ttcacttgga aactcgcctt ttacagctgg atcaaggaat gaacgattga agaacgcatc
    16201 tgctatttgc gctgctttaa catcttcagg gtttgattcg tctcttggat agcttggtgt
    16261 cagattcaag atgataccaa taacaccacc ttgctccatt tcatggtaag atttgatggc
    16321 taacgctgaa gccaacgctt catgatagcc aacttggatc gcttttttca tatctgactc
    16381 ttctggataa tgccatcgat ataaataacc tgcttcgact ggaacgattg gttcattatg
    16441 agtaaaccat ttttttactt tcgaaccaaa caattcaaaa caacttttgg catatttttc
    16501 ataggcttca accgtttctc ggttcaacca tccgcctttt tcttgcagat acatcggcat
    16561 atcgaaatga tacagattca caaagggttc gataccgttt tcaatcaact catcaaaata
    16621 acgatgatag aaacgaacgg cttcttcgtt gattgttcca gattcatcag gtatcaaacg
    16681 gctccattgg atagatgttc gaaatgaatt atgcccagtc tgtttcatca actgtacatc
    16741 ctcttgatac ttcgtataaa cttgcgaggt tttttcaggt cctacttgat caaagaactt
    16801 ttgcggttct tttttgtacc aataatcaaa aatgttctct ccttttccat cgcctgaaat
    16861 ccttccttct gtttgtgggc cacttgctgc agaaccccac caaaaatttg ctggaaattg
    16921 atattttttc atcaaagcac ctctttttct tttttagttc gttttagttg attccatgta
    16981 tgatattttc catcacaatc actttttcat tttcttcctc ttcttttttg attcgtttta
    17041 acagctgttc tgctgctcgt tccccgattt tatctgttgg tggcgtgatc gtgattttcg
    17101 gaaggatact cagatcgttt ttatctaaat aatcatagtg actgaacgca atatccttcc
    17161 cgattctgac accttcttga ttgaaacatt cgatggcacc aatcgacata ttgtaattgc
    17221 tgacaaaaat agcagttgcc cctttttcta ataatgcttt tgccccgtaa tagccgcttt
    17281 ttctagaata gtctcctgta aagacctcta attggatcga tggatcattt tggaccgctt
    17341 ctttggctcc tgctaaacgt tctcttgcta cgtagtctgt ttgagtggca gcaataaatc
    17401 cgattttttt atgtccttgt tcaccatgat gagcgatcac ttttgctaca ctttctcgat
    17461 cattcactaa tattgtatca atacctgctg gtccttctgg acaattcaat gcgataactg
    17521 gaatactcat ttttgtgagc atttcaaatc cagaccactc ttcttcggat aagaagacaa
    17581 tcagcccatc gatcacatgc ttcatcaggt attcaatttt ttgttcaatt ttttctggct
    17641 gatcggcaaa cccgcttaat aataagctat acccattttc ttcagctact ctttcgatcc
    17701 ctgagacaac ttccgaccca aaacggctgg aaatcccgtt tatcaaaagt ccaatagaga
    17761 agcttcgatt attcttcaac cctttagcaa tgatgttttc tttatagtcc aacgctgaaa
    17821 tcgcttctgc tatttttttc atgttctttt ccttcagttg ctgaccattc aagtaacggg
    17881 aaactgttcc cactgaaaca ccagccatct tagccacatc acggatcgat gccatacatt
    17941 ctcactcctg ccagttacat ttgatttctc tttcttgttg ttcgattatg atgaccgcat
    18001 tctttgcata gtgttgcttg tcatcaatat ccatataact aaagtcttca gtagagcaac
    18061 ttcctctcac tattaattat acttaaacaa gtatttgaac cggttcattt ttaatatagc
    18121 atttttttaa aagattgcaa cactttttta aaacgctttc tgaaagtggc ggattttttg
    18181 cctttttaaa attttattct aaaatttact ctatttgtgg gtgttttgtg cgtttttctc
    18241 ttccatccgt ttgaagtttt acattccaat ggtataattt ctttatccta tcaaatgggg
    18301 gaagtatttt gaagaaatta atcgtactat ttattttgtc tgcgggactt ttgacattga
    18361 ctggctgtga tttgtttggc ggctctgacc aatcctcgga cgaaacaacc gattcttctg
    18421 tcttaaaagc ggaaaaagca gataccacca acagtgtata tacgctaaaa gtacgtaaag
    18481 atatggattt atccgcggga cagttgacat ttacagataa aaaaatggaa tggacacgca
    18541 cgtatcagac acaaggaact gattcttctg aatcatctga agaaaaaaca gtgctgacag
    18601 atatcaagat cactaccaaa gatgacgaat atattatttc aggaaaagaa aataaaaaag
    18661 aaacaacagt catatttaca aaaatcggta attaccgttt gaaggatgag gatggcaaca
    18721 tctacagtct atagtgccgt ctgttggatc ttcttttgtt tctccccttc ttttctgcta
    18781 tagtaaagaa gcaagatgat tgtaaaggag acgaaatgga tgatcgatag tcctgattat
    18841 tgtacatgta ataacaacaa aaatatccat acagaattta atgaccaagg aagcttgagc
    18901 atatgcgaca actgtcacaa actagtcaaa gattcattta aaacatttga atcttatcct
    18961 gttcaaaatt atgtaaaaag tagaagaaga taaacaaatc caagcaaaac tcactatggc
    19021 tgatttttat gaacttcaaa ctcagcttct tcctttgatc aagcttcatc agtaaaacaa
    19081 acagtggatc atttcagttt acaaatcaaa gagtaaagat ttatttattt caaatatttg
    19141 aatataaaat aaccaaacga tagaaaggct tattctacat cacgtagtaa ttttt
//
LOCUS       DARPZF010000048        18966 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.050, whole genome shotgun sequence.
ACCESSION   DARPZF010000048 DARPZF010000000
VERSION     DARPZF010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18966
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.050"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(21..251)
                     /locus_tag="SLE65_002132"
     CDS             complement(21..251)
                     /locus_tag="SLE65_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449405.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(687..1253)
                     /locus_tag="SLE65_002133"
     CDS             complement(687..1253)
                     /locus_tag="SLE65_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEI8449406.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1253..2209)
                     /locus_tag="SLE65_002134"
     CDS             complement(1253..2209)
                     /locus_tag="SLE65_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEI8449407.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2209..2865)
                     /locus_tag="SLE65_002135"
     CDS             complement(2209..2865)
                     /locus_tag="SLE65_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEI8449408.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3235..5253
                     /locus_tag="SLE65_002136"
     CDS             3235..5253
                     /locus_tag="SLE65_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEI8449409.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5323..5529
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5680..8094
                     /locus_tag="SLE65_002137"
     CDS             5680..8094
                     /locus_tag="SLE65_002137"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEI8449410.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8442..9995
                     /locus_tag="SLE65_002138"
     CDS             8442..9995
                     /locus_tag="SLE65_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HEI8449411.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10376..12160)
                     /locus_tag="SLE65_002139"
     CDS             complement(10376..12160)
                     /locus_tag="SLE65_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8449412.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12175..13896)
                     /locus_tag="SLE65_002140"
     CDS             complement(12175..13896)
                     /locus_tag="SLE65_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8449413.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13996..14757
                     /locus_tag="SLE65_002141"
     CDS             13996..14757
                     /locus_tag="SLE65_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEI8449414.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15724..15992
                     /locus_tag="SLE65_002142"
                     /pseudo
     CDS             15724..15992
                     /locus_tag="SLE65_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16664..>18966
                     /locus_tag="SLE65_002143"
     CDS             16664..>18966
                     /locus_tag="SLE65_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449415.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVET"
BASE COUNT         6231 a         3366 c         3805 g         5564 t
ORIGIN      
        1 ctcattaaaa agcataacca ttactccgat ctgtttttaa aattagtttc tacctctaat
       61 atatatcgag tttttatttt gccttcagag aatactgttt ctttttttgc agttacaggt
      121 tgtttatttt cggaaaaagc taatatagct aagattgaaa catccatctg gaatttatct
      181 tttttactgc tttgatcata aaagtctgca tattcatcac tgatattttt tctaataaat
      241 tcttccatca taaaaatcac ctcaaaacga ttatacgaac ttacgttctt gttgtaaagc
      301 gatatttgag gggcaaaaaa ggggcataat ttgactgata ttaagttagc tattgatata
      361 tgaatgacat acaaaaatat aaaatctttt aaaaatgctt atatatcaat gtttttgcca
      421 ttcttttata tatctgttat atgtcaaaaa aatgtgttca atttcaattt gtatttgaat
      481 aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaat caaaaacagc
      541 ttctcatgtt tttgatttgg ttggacttat taccgcagat ataagctttt gagcaccgtg
      601 aataaagagg ttatgaaatc aacgctctaa cctgagtatt agagaaaaaa acgcaaaaca
      661 tatcatttat gttttgcgtt ttttatttat ctttttttct caatacaata taaaataggc
      721 ggctggttct tttggttgat aaaccgataa ttcagcacat tatatgtttc ctgtggcagt
      781 ttggaacaaa aagaatcaac catatccagt tctttttctc caccttcatg accatagtag
      841 acgacaagga tcaatcgtcc gcgaggcaca agtcgtttca atatttcttc catagctgtg
      901 cgtgtagtct ctggcatagt gatgattgct ttatcacttt ttgggagata ccctagattg
      961 aaaatccctg ctttgagatt ttgttgttca gctatcactt ctcctaacgt ttcgtggcct
     1021 tgtagaaaca atgagacacg ttcttctaac tgacgctgtt ctagcctttc acgagtagca
     1081 tcgattgctt gttgctggat atcaaaacta tagacatgac cagtttttcc gatgtgttct
     1141 gctagaaaaa ccgtatcgtg gccattgccc atcgttgcat ctacgacgtg atcccctggt
     1201 tgcaagattt cttgcagtaa tgtatggctg aaatgcaaag cagtttgcaa catcagacgc
     1261 tcaccttttt ccgtacatca tattttcctt ggaagctatc tctgcgaaga agttcttcat
     1321 caattgcatt caagacttcc cattttttca agctccacat tggtccaatc aaggaatccc
     1381 acggcgcatc ccctgtcaaa cgatggatga tgatctcttt tggtatcatt tccagctggt
     1441 cgcaaatgac attgacatag tcaggacggc tcattaattg aaggcgacct tcatgatagt
     1501 cccgcaacat tctcgttttg cgcatcagat gcatcaaatg gagcttgatt ccttggatat
     1561 ctgaatctaa aatggtgcgt ctgacatttt ctttcatcat ttctaaactt tcgcctggta
     1621 atccgttgat caaatgcgta caaacacgga tattatgttt gcgtaattta gccacgccat
     1681 ctaaataagt ttgataatca tgtgctcggt tgatcagttt tgaagtttct tcaaaagttg
     1741 tttgcaatcc aagttctacc cataaataca tccgctcgtt cagttcagca aggtaatcaa
     1801 ctacttcatc tggcagacaa tccggtcgtg taccgactga taatcctacg acacctggta
     1861 aattgactac ttgctcaaat cgttctttga ttatttcaac tggcgcatgg gtgtttgtaa
     1921 aattttggaa ataaacgatg tattgttgga catgaggcca tttttgatgc atcatgtcga
     1981 tttctttctg gaattggatt ggaagagggt cttcaggtgc aacgatcatg tctcccgaac
     2041 cagatacact gcaaaaagta caaccgccat gggcaacagt cccatctcga ttcggacagt
     2101 caaatcctcc atcgatcggc accttgaaaa ttttcccgcc aaactcattt cgtaaagcgt
     2161 aattccaaga atgatatctt ttatttcctt ctgaataagg aaaagtcatt aaaagtcctt
     2221 ctttctgtaa gagttatcta tttgttttct tttttctcta tacactggat aagtcaggca
     2281 cagccaagaa agactgagta agtagccgcc gatgatatca gtaggaaaat gaacgcccag
     2341 ataaatgcgg cttatcccga cacttactat aataaacatc atcagcaatt gaagcaatgt
     2401 gcgtaaggtt cttttttgaa caaaagctgg aagcagaaat agtaaagaac cgtaaagaat
     2461 catactgcct gctgcatgtc cactagggaa actgtaactt gtttcaacta ctaagtgcgc
     2521 caatgaagga cgctctcgca tgaaaaatag tttgatcacc gggttgatga ttccagcaat
     2581 tacaataaat ccagaaacga accaaaatgt ttctgccctt tttttcttat accacatcca
     2641 taaagccgca caagcaaata aaatgatgac ggtaagagga ttaccgaatt tagtcataaa
     2701 gagttggtag ctgttcagat caggataaga agctctgaca atgcctgtaa accactgatc
     2761 gaaaccagaa agccacgaca gatggaactt tacgatccag cccaaaatga aaaacaggac
     2821 aagaaagaag ctaccagcca cctgaaatga tgttttatat ttcatacaat tcctcctttg
     2881 aagcaatgac ttattatagc atttttggtc cagcgaaaaa aacggtaaag agataaaacc
     2941 aatgtatgat tcctctttga ataaccaata ttcttataaa aaaaataact gtaatcggaa
     3001 agacattttt tggtaatgca aatgaaatgt tagggaaata aaatcagtgt ttttcgaaat
     3061 ccttttaaac aagaacgtag acgtaggaag aacttgaaaa tgaacagaag ttgttcatta
     3121 cggtaaatta caatatgatt acaaaaaaca acaaagctct taaataactt ttaataaata
     3181 ttaagagaag ttataattat taataataga taaattgaag ttggaggata gaagatggaa
     3241 aacattgcaa gaaaagaacg gagacgttta gaacagacca aacgttttcg aaaagcaaaa
     3301 cgaggggcag caatcgtggg aactgcgatg gtaggctgtt ctgtcgctgc cccattagta
     3361 cagccggttc ctgttcaagc ggatgaaaca cctgttcagt tcggcgcaag aatcaataca
     3421 gcggcattta tcacagaaat tgctacttat gctcaaccaa tcgctcaagc caacgatcta
     3481 tatgcatcag tgatgatcgc acaagcagtt gtagaaagcg gttggggcag tagtgcgtta
     3541 tctcaagcac cttattataa tctttttggg ataaaaggca gctatcaagg acaaaccgtc
     3601 tacatggata cgcttgaatt tttaaataat caatgggtaa ataaaaagga gcctttccga
     3661 caatatcctt cttttgctga atctttcaat gacaatgcct atgtacttag aaatacttca
     3721 tttggcaacg gttattacta tgccggtact tggaagagca acacgaaatc ctatacagat
     3781 gcgacagctt gtttgacagg gcgttatgcg actgatcctg gttacgcagg caaattaaat
     3841 aatatcatcg caacttacgg attgacccaa tatgatacac cagctagcgg aaacgcaggc
     3901 ggtggagcga ctacaggtgg caataatact ggaagtgcag gtagtactgg cggttcaagc
     3961 aattctggta atacaaactc aggttcagca acttcgacca cttatactgt ccaatctggt
     4021 gattctgttt ggggaatctc aaataaattc ggtatcacaa tggatcaatt gatccaatgg
     4081 aacaacatcc aaaacaattt catttatcca ggacaaaaac tgacaatcaa aggtagccag
     4141 gaaaatggct cttcgacgaa taattccggt aacaatacca actcttcagg aaatgctggt
     4201 acatcaaacg gaggacaaac aactggtgcg aaatacactg ttcaatctgg tgattctgtt
     4261 tggaagatct caaatgatca cggaattacg atggctcaat tgattgaatg gaacaatatc
     4321 aagaacaatt tcgtttatcc aggacaacag ctaatcgtat caaatggcgg ttcttctaat
     4381 gctggagcaa atactggctc aaatactggg aatacaagtg gctctagttc gtccagctca
     4441 agttcttcta atacagcttc aggaacgaaa tatacagtta aagccggaga ctctgtttgg
     4501 agcgtctcaa ataaatacgg aattacgatg gctcagctaa tccaatggaa caatatccaa
     4561 aataacttta tctacccagg acaacaactg actgtttcaa acagtggatc aacaaacagc
     4621 acgtcaggta atacaggttc gtcaaccaat acaaataaca gcagttcagt taatactggc
     4681 agcagttcgt ctcaaggcac ttataccgtg aaagcaggtg aatctgtttg gagcgtggca
     4741 aataaaaacg gcatcacgat ggatcagtta atcgaatgga ataatatcaa aaacaacttc
     4801 atttatccag gacagcaatt gatcgttaaa ggtggaactt cggcaaatac aaatacaggt
     4861 tcaactactt ctgcagcgaa accaaataca ccgaatacgt ctgctacgac aagtacatca
     4921 tccactggta atacgatgta taccgtgaaa gcgggcgagt cagtttggag cgtagcgaac
     4981 aaacatcata tcacgatgga tcagttaatc gaatggaata atatcaaaaa taatttcatc
     5041 tatccaggac agcaagtgat tgtgaagaaa ggttcatctc aatcaacaaa ccaacaatca
     5101 gttactggtt cgaaaaccta tactgtgaaa tctggagaat ctgtttggag tgttgctgac
     5161 agtcatggaa ttacaatggc tcaactaatc gaatggaaca atattaagaa caactttatt
     5221 tatccaggtc aaacgttgat tgtagctaaa taaaatagct gttcgaagaa ataacgattg
     5281 aattccacaa aaatatttgt tactataagg ctacttaaat atgacaacac ttgaaaagga
     5341 agtagtaaaa agactgaagt ttcagagagc gcatggctgg tgagaatgtg cacggatgct
     5401 tttgaactcg cctttgagtt gcccttgctg aatacccgag taagcaagcg gcggtgacgg
     5461 ccgttacaac gttcgaggcc ttttcactaa ggtaaaatta ggtggtaccg cgtagattac
     5521 gtcctataaa aagagcaatc tttttatagg atttttttat ttcttttgtg aagtttgaga
     5581 aaacaaagca aaaggaaata aaaataaaca gattctgccg gttttttcgt tatatttata
     5641 atagaaacaa gtgttttcaa tagaacagga ggacagcaaa tgagttacaa tcataaagaa
     5701 attgagaaaa aatggcaaaa atactgggca aaaacgaata ctttcaacac ccatgatgat
     5761 cctgaaaagc caaaatttta cgcactggat atgtttccct atccatccgg tcaagggcta
     5821 catgtagggc atcctgaagg ttatacggca acggatatcc tttcacgtgt gaaaagaagt
     5881 caaggataca acgtgctgca tccaatgggg tgggatgcat tcggtctgcc tgctgaacaa
     5941 tatgcgctag atacaggaaa cgatccagct gagtttaccc aaaaaaatat cgaaacattc
     6001 cgacgccaaa tcaattcttt aggatttagt tatgactgga atcgcgaagt gaatacaact
     6061 gatccggagt attataaatg gacacaatgg atctttacga agctttatga aaaaggtcta
     6121 gcttatgaag cagaagtagc ggtaaactgg gtacctgaat taggaacagt tatttcaaat
     6181 gaagaagtga tcgatgggaa aagtgaacgt ggtggctatg atgtagtcag aaaaccaatg
     6241 cgccaatgga tgctgaaaat cactgcttat gctgatcgct tattggatga tctagaatta
     6301 gttgattggc cagaaagcat taaagaaatg caaagaaatt ggatcggtcg ttcagtagga
     6361 gcaaatattg aatttaaagt ggctggtacg gataaatcct ataccgtatt tacgacacga
     6421 ccagatactc tattcggtgc aacttactcg gttcttgcac ctgaactaga tcttgttaga
     6481 gaaattacga cccctgaaca aaaagctgct gtagaagctt atatcgaaga gacagctaaa
     6541 aaatcagatc taaagagaac ggatcttgca aaagaaaaaa caggagtatt tactggtgct
     6601 tatgcaatca atccagttaa tggcaaggaa atcccaatct ggatcgccga ttatgtatta
     6661 tcttcatacg gcacaggagc catcatggct gttccagcac atgatgaacg tgactttgaa
     6721 ttcgctcaaa ctttcggact agaaattctt ccagttatcg aaggtggaga tgttgaaaaa
     6781 gctgcttaca cagaagatgg tacgcacatc aactctgaat ttctagacgg catgaacaaa
     6841 caagaagcaa tcgataaaat gaatgaatgg ctagaagaaa atggcgtagg gaaaaaagaa
     6901 gtcagctatc gcttacgtga ctggctattc tcccgtcaac gttactgggg tgaaccaatc
     6961 ccaatcatcc attgggagga cggaacagtc acagctgtcc cagaagaaga gctaccatta
     7021 cggttgccta agacaaaaaa catcaagcca agcggtactg gagaatctcc attagcaaat
     7081 atcgaggagt gggtcaatgt cgttgatcct gtaacaggta aaaaaggccg tcgcgaaacg
     7141 aatacaatgc cacaatgggc aggaagctca tggtattacc tgcgttatat cgaccctcat
     7201 aacaaaaaag aactagcaga ttatgaaaag ttgaagcgtt ggctaccagt tgacatctac
     7261 attggtggag cagaacatgc ggtacttcat ttactatatg cacgattctg gcataaattc
     7321 ttatacgata tcggtgttgt tcctacaaaa gaaccattcc aaaaactata caatcaagga
     7381 atgatcttag gcgaaaacaa cgaaaaaatg tcaaaatctc gtggtaatgt agtcaatcct
     7441 gatgatgtgg tcgaaactta cggtgcagat acactgcgca tgtacgaaat gttcatgggg
     7501 ccattagatg cttcgattgc ttggagcgaa aatggcttag aaggaagccg taaattcttg
     7561 gatcgtgtat ggcgtttgat cgttgatgag aacaataaaa tgcgtgaccg tatcactaca
     7621 ttgaatgatg gcaagcttga taaagtgtat catcaaacag tgaaaaaagt gacagaagac
     7681 tatgaaaatc ttcatttcaa tacagcaatc tcccaattga tggtctttat caatgaagcc
     7741 tataaagtgg acgctctgcc ttatgaatat atcgaaggat ttgttcaact actcgcaccg
     7801 attgctcctc acatgggtga agaactatgg gcaatccttg gaaatgatgg tggtatttct
     7861 tacgcaccat ggccaacata cgatgaagca gcacttgttg aagacgaagt agaagttgtt
     7921 ttccaagtaa acggtaaagt tcgtgcgaaa agcaatgttc cccgagactt aggaaaagat
     7981 gagctagaaa aagcagcatt agccaatgaa atagtgcaag aatatattga aggcaaaaca
     8041 gtcagaaaag ttattgcggt accaaacaag ttagtcaata tcgttgctaa ttaattggct
     8101 ctttgtcaat aaggactgat gagttgtgca aaatcaaatc tgggccagaa tgaacttcat
     8161 tctgtctcag attttttgtt atttcaaatt gattaattga ttgatcaaaa aggttttgat
     8221 tttcatgttc tcaaacacgt tcaatgtctt tttcttctga atggtcttgt aagagatctc
     8281 tgtaatcatc aaatttttgt ctattaatct tagtattttt tgatgtataa actacctgaa
     8341 attgagagta cataccaaat tcataaattt tttattagtg ggactagtga ttgtatggat
     8401 tttgacgcat aatgaatgaa gtatgagaaa aggagagaca aatggatcaa gaactattta
     8461 ttatcgaagt attatcagct aaacaaaaaa ttatcgagaa agcgaaaaaa agagcgaaaa
     8521 gaataatgtt caagctttta agcttagtat ttttctctgg tttgcttttt ttcggagctg
     8581 tatcgttcct atatcgccat atgagtgcag tagtccgttc agctgaaggg atgcaaaaat
     8641 taaataattt gtatcacttt tcgtggggag ttggcggaat aacaattgtt gtgcttattg
     8701 tttttcttct acttatttgg ctccgttacc atcaattgtc gcgtcatttc gatcaatggc
     8761 ttagtcaaag agcacaacag tttttacata ataaaccaac ttctcaagat gatgactatc
     8821 tttattttga gaagacttcg acgagtcaag cttttcggat acaaaaaagt gattgccagt
     8881 tattgctgag atcacttgat gatttaccta tctacttagg cgaaagcaaa tcaaaattcg
     8941 gaatgaacac attccatatt tttttactag aaaacgaacc cagatgggaa aaaagccagt
     9001 cttcgcctgg tggatacctg acaactaaga tgagtacatt agtcactggt tttttcctca
     9061 ttcttttagc tggaacaatc tattatggga gatacactca gccaaaaatg tcttctcata
     9121 taaatgctgc ttctcacatg acaatgaact caactaacga tacgcatata caaaagacaa
     9181 atgaagggtt gttagctgat cctaagcaaa aggtaaattt gacaacacaa aagataaatg
     9241 atctcaaact tgatacagag acgcactctc tctatatgac aacagatagt ggtgctaatt
     9301 gggtatttgt gccgattgat tcgcaatggt tgcgttttgg cgaatacacc ctgacaacgg
     9361 ggctgattcc tgaaggttat tggatggaca acacatatga tatttccgcc gatttctcat
     9421 ggtttatcta ttcttctggg gatgatgtac gtctgctgac ttcaagagat aatggtaaaa
     9481 catggcaaac gtctattatc acccaatcag ttcagccgat acgttatcga aaagcggtat
     9541 tttatggcaa cgatggtcta tttatctgta catcagccag tgggatgtct gcagaaactt
     9601 tgtacattta cactactatg gatggcggaa tcacttggat aaaaagtgga agtacaatga
     9661 tcaatcagcc agtacaaaat gtcagcttcg ttacaacttc tttaggtttt gtttcgacac
     9721 gtgaaagttt gttttataca aacaacggag gacgctcatt caaagaatca gttctgtcga
     9781 ttccggaaaa ctatcagaca ggggggatag atctttttca atcaccaaat gaagttactc
     9841 aaataagcgc gaatacgtta gagacaaaat tttatttgtt gaaaaaagga ccaatcgatg
     9901 cagggaaaat gtttgcctgc ctcttccgtt caactgataa cggggaaaca tggcaattcg
     9961 ttcagcaact atcgcaagta gaacaaggag attaaagaag agagattgtg agcctgacgt
    10021 tcagcaccga gtcacaagaa acaaattcaa aaaacagctt ctcatatttg ttgaatagtg
    10081 taactcgtga ttcggagttg acaagagcaa caagaagcga ttttgaagta tagcttctcg
    10141 tattttacaa gatcgtgtct tattgccgat aggttgtctc ttgaacaccg tttattcgta
    10201 aaaagggatt gtgacaagtc ttttgtcact acttaccgaa cgaaactgaa ggagctatcc
    10261 aaaaagtatc attagtatta ttctttgtgt ttctagtggc accactagta catttaaaaa
    10321 agctatcgat catggactaa tcatacatga tcgatagctt tttagataat gtttgttacg
    10381 ctatctgaaa ttgactatta taaagactgg cataaagcgt tggtgattgg agtagttcag
    10441 aatgtgttcc tttttcgacg atatcgccat tcttcattac aaggatcatg tctgcatttt
    10501 caatcgttga caaacggtgt gcaatcacaa aacttgtcct atcttttgtc acagcttcca
    10561 ttgcttgctg aatcaatgct tctgttcgtg tatctacgct agaagttgct tcatctaaaa
    10621 taacgacagg aggattcgct agaatgactc gagcaattgt caataattgt tgctgtcctt
    10681 gagataacgt gccgttttcg ctagaaatga tcgtatcata tccgtctggc agtgttcgaa
    10741 taaagtgatc acattgtgcg atttcagccg cttcgataat ttgttctctt gtggcatcca
    10801 ttttcccgta ggcgatatta tcagctaccg ttccttcaaa cagccaggta ttttgtaaaa
    10861 ccatcccaaa agaacgacgt agttctccac gtgaaagctt ggtaatatca agaccgtcga
    10921 attcgatctt tcctttattc agttcataaa aacgcatcag cagattgact aaagtcgttt
    10981 ttcctgcacc agttggacca acgatcgcta ccgtttgttt tggctttact gaaaaatcga
    11041 cttgattcat caatatttta tctgatgtgt aaccaaactg tacatttttg aaagctattt
    11101 ttcctttcgg ttgttctaaa agtcttgcat ctggaaggtc tggaatttca tctgtttcat
    11161 ctaatatctc aaatatccta tcgattgctg ccattgcgga ttggatcgag ttgatcacat
    11221 aagaagcggt agaaattggt tcagaaatct gattgatgta ctgaagataa gcttgtaaga
    11281 agccgatcgt cacaccacct gatagaacaa gcatagcacc gaataccgca cttatgatga
    11341 aggcgagttg attaatgaaa cgaatggccg gatagatagc acagttcata aattgagcac
    11401 gtttaaaagc gttgtattgc tttttattta cttcgtgtat agcagcttct gcatgagctt
    11461 gctgattgaa tgttttgacc actagattac cagctaagat ttcttccatt cgattattta
    11521 aaacacccag ttcatactga ttctgttcag aaatctgttt gtttttgttc gcaatcttag
    11581 ttgtaacaat tgaactgcca acgatcagca ataagacgag caaagtaagc ttgctttcga
    11641 tataaaacag catcagacca gcagcagcta ttgttacgac agaagtaaaa aattgattga
    11701 tacctgtcaa taacacttga gaaagttgat tgagaccggt agttgtccga ctaatgatgt
    11761 cacctacttg atgattgtca aaaaacgaca tcggtaatgt tttgaatttt tttgtgattt
    11821 cttttcgcac cctcaatgtg atcttttcgc ttaacgctgc cattgtccgt tcctgaataa
    11881 atgaagtgat gctgcttaag actgaacagc cgatcagcaa taagacaggg aacaacaatg
    11941 cttgtttgat atcactgaaa gaaagctgtc caatacctgt ttttcttatt tctgataaga
    12001 gatcatcgat cccgattccc atgatcaagg gcatggctac gactaatagg ttcccgaata
    12061 aactgcatag aaacaatccg taaaaatatt tatgttcagg tttgatcatt ttccaaaaac
    12121 gtatcaaagc acgcgtgttc aacgtttttt tcttttccat cgtatccctt ctttctatat
    12181 tccttgtgat tttgcaaact cctgataagt ttggcaatta gacagtagtt cttcatgagt
    12241 accttgtcca acgatttttc cttcatctaa aacaatgatg ttatctgctt gttggattgt
    12301 actgaggcgt tgagcaacaa tcacgagagt tttctccgac atgtgtttat gaagggctgc
    12361 tcttaatgcc gcatctgttt tatagtctaa agcggagaaa ctatcatcga atacatagat
    12421 ctctgctggt ttgatcaacg ctcgagcaat acatatccgc tgtttctggc cccctgaata
    12481 attagaaccg ccttgagcaa caaagctgtc caatccgtca ggaagggtgt ccactagttc
    12541 ttctaattga gcgatcttga tcgctttaga caactcttct gttgaggcat attcatttcc
    12601 catctgcaag ttgcttaaaa ttgtcccgct gaataagaaa gccttctgag ggacataact
    12661 gatgtgggag cggatctgtt cttgagtcat ttgagtaaga ggaataccac caagggttac
    12721 ttttcctatc gtagggtcac taagtctcaa gagaagtttc gccaaactac tttttccaga
    12781 tccggtcccg ccaacgatcg ctgttgtttt tcctttaggt attgtgaaat caatatcttc
    12841 tagaactgga tcagagattt cagtatattt aaatgtgaca tgttcaaaag cagctgcatt
    12901 tgtctgatca aaggttggtt cagctactgt tttgatcgtc tcttcctcaa tttcgatctc
    12961 tgcttgcagt atttcttcta tccgtcgtaa tgaggcaaac gatttaggga taatgaccaa
    13021 taccatagct gcgatcatca agtaagcaag tgtcagcata gagtattcga ctacagcagt
    13081 cacgacaccg atttgtaatg ctccttctgc tacaagattt ccgccaaacc acaaaataga
    13141 agcataaacg attcccatga gcaaaaaagc aattggagtg acccaagcaa atattcggtt
    13201 cactttgatc atttgattag catagtcagc aaagctctta ttcgttcgct tttcttcata
    13261 tgattgatta tcaaaggcac ggatcatatt aatcccagta aagaattctc tcaatgtgat
    13321 ggtgatccga tccatttttg gctggatact caaagataaa ggtgcccctc gtttcatcag
    13381 tcgataaaca atccatacat aaaaaacaac agagatcaat gtaacccatg ttagtaatag
    13441 agaataacga aacatcatga gaatggtgaa aacgcaaata accggtgctg gtaagatcat
    13501 ttggcaaaat aaaacaatca tttgctggac attatcgaca tcattcgtca ttcttgtcaa
    13561 aagagatcca gaactaaaac gactgatatc cttcattgac agctgttgga atttacggaa
    13621 atatttctcc cgcgtttgga atccaaacct agcggaagcc aatgctgaaa agtaactaga
    13681 ggcaactgca gcgattgttc ctagaaacgc tacaagcagc atttcaactc caattttttt
    13741 tataactgag gcttcgccac ttgctatacc tgtgtcgatc agctttgcta ctaattttgg
    13801 tacacctaat gtaccggcga tttctaaaca gatcatcaca aaggtaagga gagcgagtcc
    13861 tttgtttttc tgtaagaatg tttttaagat agacatatta ttcctccttt tttcctgata
    13921 cttttcgatt ctataccttc aagtaacttg aaggtcaata gaaaaaagaa taaactgaaa
    13981 aagaggtgag aaaaaatgaa aaaaatgtat acgattggcc aagtatcgga actatttgat
    14041 ttgccaaaat caacgatccg ctattgggat gaacaaggat taatccgttc aagtagacaa
    14101 gaagagaatg attatcgatt gtttgatatc gatgatattt ttatgcttta tgatatcgtt
    14161 ttttatagaa aattagatat accgatcaaa cagatgaaga atttatatgg aaaaacattg
    14221 acggagttat atgagacact tgatgaaaca gaaagaagaa tccataaaga actggtggtg
    14281 atgaaacaaa aacaaaaaga gataagggag caaaaaaaac agttgaaatt gatgatcgat
    14341 acaaacgagg aagaatttcc tgtagaagag atcccttttg actgtatgat ctcaacggag
    14401 tttgaagata ttgtggaaat caaaaaattt ctacctaact attcaagctt tgggatgatg
    14461 agtatgccag cttccagttc acagacgatg tatggatttt ttatcgaccc tagtgaagta
    14521 catttattta ctcaagacgt gatttgggag aaaaaagata cggctgttta tcgtcgattc
    14581 ttattgaaat ccgagatgaa ccatgcggaa cgtaataata ttttagaaat cagagaaaga
    14641 atgtatgaaa aaggatggaa aacaggagaa gtgatcggcc agtatctatt gacgaatacg
    14701 gatgaaaaca atatcagaac tgaatattat catgcatgga tagaaatgaa aaaataggaa
    14761 atatgtgttt aagataactc gaaaatgatg gttgttttag ttataaagaa aaattttctg
    14821 gttcgattac gggtttaatg tgggggatta ttagtcgtgg atagatagaa ttttagtttt
    14881 ttagaggaaa tatgtcttta aaaatggaat ggttgcaatt cttagcgata tatacgatgt
    14941 aattgtcctc ttaaaaaagt atggaaaaat aattgtattg ggtgttatgt ataattcatg
    15001 gtgaactgag actaatgaga agaaaaattc atattgttat gagtgagatt gtatcagatg
    15061 agaatgataa attaaatagg tgcataaaag cattacactt aaaatacatt gttgcttaca
    15121 ttattacaat atgttaataa ggcaaaaata aatagatgga ttgaataaac atatttttta
    15181 atcaaatagt ccctactgtg actttcctca gctatcggtg atactaccga tagcattttt
    15241 ttgcttataa aataattata agtatttaga gatttttctt ctaacattct tcaaacaaga
    15301 aaaatcacaa aggttattgt tatttttata tattcttttt aagaatgatt gtttttttat
    15361 agaaatttta aaaaataaaa cacgttattg atggatagtt agtttgttat ttggtaatat
    15421 tatagaagtt gactggtagt gatttatttt tcgtcgtttt ataaaaatgt tattttttgg
    15481 aaaaattcac aaatatgtaa cgaatgtttt tctggaattt gctgtgttaa aaagcagtat
    15541 gactaatata aatactattg tcatttatgc aattttttat ggatagtaat tttagagggg
    15601 aatcaatgaa ggaagaatag aagggaaaaa tagttgcaaa tacgccagtt agcaaaaata
    15661 gcaatacatc ttcaagcttt aaaattcgag agaatcatct tggtagtgga atcaactaca
    15721 acaaaaggat taaaccaatt aatagataga attaccaatg gaaaaataga aaaggtagtt
    15781 attctataca aaagttgttt aattcgcttc ggttatgaac ttagtgaaac cctttgcaat
    15841 atatggtaca gaatatagaa attattgaca ttacagaaaa tgatgaagat ttaatacaga
    15901 ttgtcactat ttgtagatac cttttacaag gaaaccgagc caataaagct aagaagatga
    15961 ttaaggagtt gatggaagac gatacaagtt aagaaagtga aactacgccc aaataaagag
    16021 caaaaagagt aattggacgt ggaaaatgca agaaatgaac catcgattcg gtggacagtt
    16081 tattagtaat gacggtttga gaacatccat gacgagaatg aaggaacatc ctaaatgcgt
    16141 ttagttgaac caagtgccaa ataatatggc caaataagcg atcagttatc gatgaatccc
    16201 aagtattcta aactatatat tcattttgat gctaagcatt gatatatttt tttgggattg
    16261 atgaaggtta accaatacag ggactcactg atgaaattct agagtctgac cttggtatca
    16321 acgatttagt gattgtttct aatggaaaag tataaaagta tataagtaca ttaacaaaat
    16381 aactattagg gttacgctcc agcttgtgca aggcactggc aggaggaatc gtgaaatcat
    16441 aattatggtt aagccacacg gacaactaaa agtcatacaa agctatcgaa tcaatcaaca
    16501 gaagacaatc ggcaatcatt agctttgttt acagcttaca ttgcaacgct tgagttgaac
    16561 cgaaaatacg agggaggtaa cgcagccatt ttgagttggg gaatcttttt agaaaattat
    16621 cgggtacctt gttgtttagt caaaattata agggggagta atagtgagga acaaatttca
    16681 taaactgtta agtatgtttc tagttatgct tattgtgatc aatcaatttg ggaacataac
    16741 ggttctagct gagtctttag cagaacagcc agagcgttcg ctgacgatcg aagttgatca
    16801 agaggaggct gctttgggtg agcagttcca gttgcgagtc agaggaacac cagacctgct
    16861 aaatgcattg gtcattgata agagtgagga tttgattgaa ggggaagtga agcaactcaa
    16921 tgattacgaa cgtctgatta cttattcttc ccagcattca ggtaaatacg aattgaccgc
    16981 aagaagcggt gatattcaat caaatacggt ctcaatagaa atcagtgtac cagaagaaag
    17041 cacaagtgag tcttttaatg taccagaaga aagcacaagt gaatctttta atataccaga
    17101 agaaagctta agtgaatctt ttaatgaagc cagatcatct gagccatcta taacgcagga
    17161 atctcagatt gaaagacaag aggagctctt gaattatgac atcggcatct ctgctgagcg
    17221 ccccactttg ccgagcaggc atacacaaac gttaaaggga tacattcaag gaggcgctgg
    17281 cgatattctt gaagaatatg gggagatggt cgtacgagtt cctagagcat cgattggctt
    17341 aattgagttc attagagtgg aggtcgctga tgattcacct ttaaagccac tggcatttta
    17401 ccaagaaggc acagacgttg tttttccatt tacctttgat tatgaaggat taaatgaagc
    17461 cgctcagtcg tatacattca gtatcacgtt tgaagttgct ttctttcaat caggcggtac
    17521 tgagccaaat aatgactttc aagtgagtct tacttatgct gagcgagcag caaacacgga
    17581 attttcaatt acgcctattc cttcatcaag acccattttt tcgaaattat actatggctc
    17641 tagagaaatc gacagccaag gaaatcttgg gaatctgctg attgacgggc aagacgtgac
    17701 caacagtaat aaatttattt tgcaggtaaa ttatgaagga tcacgaaaag acggtgtagt
    17761 ggttaccgat gtactaccgc aaggaacaac tttggcaccg aatccgacta catggagttc
    17821 cactggaaat agagaaccta tttcaggtgg ggttcggatc gcagaagtaa cgaatccagg
    17881 tgaagcaaac gttagaactc attatgtttc cgaggaattt gtggacaaag tatcttttaa
    17941 taaggaaacg aatacacttg ttgtggactt tggtaatcta gcagagggtc aatcgtattt
    18001 tattgaatat gctcttgaag tgaccgatgt cgacttgttc aatgaaggaa gacaagagga
    18061 tgggttttct cggaatcgag cgagtatgac ctacaataat caggtaatga gccgagacta
    18121 ccgcttgaga atccctgaaa gtaatcttcc ggcaatctct ttaagaaaaa gtgtggacaa
    18181 aaatgttatc aatctcaatg aaaatgaact aacgtatact ctgcatgtct cgatgttttc
    18241 tggaacaaga aatacgcttg ttattgaaga tgttttggaa gaaggcatgg aatttgtgtc
    18301 atttctatca gatattccct ctttcattga tgccgaagtc aataatggaa tagttcgttt
    18361 cagtgcgaat aatacgattg gtggtccgac aagttttacc ctctctttta aggtcaatgt
    18421 agaggcgtat gcggtcggcg atcaaatttt aaactttgca acgcttgtga atagtgacaa
    18481 tcgattgaat acgagtactg taagaacaag gaaaatcgat gggcgtatta aagtaattaa
    18541 aactgatgag aatggccaaa ggctggcagg agcaaaattt gaaattttat caagcgattc
    18601 acaagtgata caagaaggta taacggcaga aaacggagaa tttttaagtg aaccgcttcc
    18661 tgtaggtagc tatcaagtcc gagaaacaga agcaccggaa gggtatcttt tagatgcgac
    18721 ggtacatgat gtttttataa atgaatactc catagaagaa gtgacgttaa ccattgaaaa
    18781 catccttgat acgggtggtg ttgaactaat taaacatgct gaaggcagtg gtgaagtcct
    18841 tcaaggagct gtttttgagt tacagaaccg agaaggagaa acgctacaaa ccggtttaac
    18901 tacaggagaa gatggaaaac tggcaattga cggtttagca ccaggagcat atcagctggt
    18961 agaaac
//
LOCUS       DARPZF010000049        17903 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.051, whole genome shotgun sequence.
ACCESSION   DARPZF010000049 DARPZF010000000
VERSION     DARPZF010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17903
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.051"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(193..1494)
                     /locus_tag="SLE65_002144"
     CDS             complement(193..1494)
                     /locus_tag="SLE65_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEI8449416.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(1724..3682)
                     /locus_tag="SLE65_002145"
     CDS             complement(1724..3682)
                     /locus_tag="SLE65_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HEI8449417.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(3859..4125)
                     /locus_tag="SLE65_002146"
     CDS             complement(3859..4125)
                     /locus_tag="SLE65_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEI8449418.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(4635..6761)
                     /gene="pnp"
                     /locus_tag="SLE65_002147"
     CDS             complement(4635..6761)
                     /gene="pnp"
                     /locus_tag="SLE65_002147"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEI8449419.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(6949..7218)
                     /gene="rpsO"
                     /locus_tag="SLE65_002148"
     CDS             complement(6949..7218)
                     /gene="rpsO"
                     /locus_tag="SLE65_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEI8449420.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            7469..8032
                     /locus_tag="SLE65_002149"
     CDS             7469..8032
                     /locus_tag="SLE65_002149"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEI8449421.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(8285..8806)
                     /locus_tag="SLE65_002150"
     CDS             complement(8285..8806)
                     /locus_tag="SLE65_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEI8449422.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(8809..9651)
                     /locus_tag="SLE65_002151"
     CDS             complement(8809..9651)
                     /locus_tag="SLE65_002151"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEI8449423.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(9644..10369)
                     /locus_tag="SLE65_002152"
     CDS             complement(9644..10369)
                     /locus_tag="SLE65_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HEI8449424.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            10545..10841
                     /locus_tag="SLE65_002153"
     CDS             10545..10841
                     /locus_tag="SLE65_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449425.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            11409..13001
                     /locus_tag="SLE65_002154"
     CDS             11409..13001
                     /locus_tag="SLE65_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEI8449426.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            13014..13754
                     /locus_tag="SLE65_002155"
     CDS             13014..13754
                     /locus_tag="SLE65_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEI8449427.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            13922..15271
                     /locus_tag="SLE65_002156"
     CDS             13922..15271
                     /locus_tag="SLE65_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8449428.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(15399..15989)
                     /locus_tag="SLE65_002157"
     CDS             complement(15399..15989)
                     /locus_tag="SLE65_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HEI8449429.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            16136..17488
                     /gene="brnQ"
                     /locus_tag="SLE65_002158"
     CDS             16136..17488
                     /gene="brnQ"
                     /locus_tag="SLE65_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEI8449430.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         5147 a         3627 c         3420 g         5709 t
ORIGIN      
        1 aactagatca tcaatcgtaa gcatcgcaaa ttgatttcta ccattcgtat tgtttttaga
       61 catcatagct atcactcctt gcattcgttt tcataaatct attataaaag aaaagactgt
      121 agatatcatc cataaaatgg actttgtcta cagtctgagg ctgtgacaaa aaatgtcaca
      181 gccttttttc ttttattcta tttttctttc cgtggactct actttgaaat aatcgatatg
      241 tgcatgctgg tattctaata ccgtgaaacg gaatgatgca atctcaatga ttgttcctgc
      301 ttttatttct ttatatcggc tagaagcaaa gcccgcaagt gtagtaaaat tcgtttcttc
      361 aaactctgga atctctacat gaaaataacg ctggaaatca tctaatgtta gtttgccgga
      421 gatgatataa gagccatctg actgttccgc tatcaatgct tcgtccaaat ctgtctcatc
      481 tcggatttcc ccgacgattt cttctaaaat atcttcaatc gtcactaagc cgcttgtccc
      541 tccgtattca tcttttaaga tagcaatatg ctttcccttt tttcgcatga tcgtcaataa
      601 tttttttata gggatcgttt cagttgttac gatcggctct tcaatcaact gttctactgt
      661 cagctggtca tctttataag attgcttgat caaatctggc aaggtgacat aacctaaaac
      721 attgtctttt gattctaaga taaccggata gcgagtatgt ccttgttcaa tcgaagcttt
      781 tatcgcttct ttgacggttt ctgaagcttc gaatacttgc atggacgtac ggtctacttg
      841 tatatctttt gccaaggtat catcaaattc aaacacgttt tccaaataat gatattcttc
      901 tttggtcaac tctccttttt cataagaatt caatgcgact aatgtcagct cttcttgaga
      961 caatgtctct tctccttcag atacgagacg cacacctaat agcttcccta gccctgcagc
     1021 tgaatgattc aatacccaaa taaaaggaaa cattacttta taaaaataat gaagtggttt
     1081 aactacgaac aagacgacct tctccgtatt gacgatacta tagctcttag gaagcagttc
     1141 gccaataacc acatcgatat acgtaactaa aataaatccc agcgccacag agattgtact
     1201 gctaatagcc gaactaaaag gtagtttacc gatcactggt tctagtaaag ccgcgacaga
     1261 tccttcaccg acccacccga tgatcaaacc ggttagcgta attcctaatt gactagctga
     1321 taaatagtta tctaaatggt gtgtaacatg aagagctagc ttggcgttct ttacattttc
     1381 cttttctagt tgttccaatc ttgatcgtct gattttcact aaagcaaatt cacttgctac
     1441 aaaaaatgaa gtaattgcaa tcatcaaaaa taaaataatg aaattgataa ccatattctc
     1501 ccgcctttct ctttttctat tgtacccttt ttctacaaaa agattgaaaa taatgcgtat
     1561 tcatatttag gaataaaaaa ggagatgcgg catttttcag ccacatctcc ttatcacttc
     1621 aaaatcattg cgttacttgt tgctaaacag ctttttcatg acctctgata aacggtgttc
     1681 aagtagctga cattcgacat tagttcaggt caaagcgcta ctttcacaac cgctctttca
     1741 accatgtttt ccgagtattt ccaatgataa gcggaacagt ttcatgtttt acttcgctgt
     1801 actctagccc aaaccatgtt tctggcgagg tagcgatttt tttgattgcc agttttgcct
     1861 gcatgatttg acgttgccat tttcctagag ttgtcacatt ggaaactact tcatcaatca
     1921 ggacaaattg gaaatcgcca acttctcgcc ctggtgtcag agagtatctt tgtggctgtt
     1981 ttggcaaacg gccttgtttc atcaaatcat ggatgacttg gcgaacatat acgttgattt
     2041 cctgttggac cctgaaacct aagaacagat tcacttggac aataaaatca gtgtccatca
     2101 tatctacttg atattctttc gtatatggct catccgtcac ttccacatga acaaaccaat
     2161 agactcgtgc tcttttaggc cgtttatcta aaatcgaata gatgaactgt cggccaactt
     2221 tatcttcagc catatcagga accaagaaga ccacatttgt ctgatagatt ggtaaagaag
     2281 tatcatcacg taattctcta agctgcggga tataatctct caaagacaca tcctcggttg
     2341 acgattcgcg aataatgttc ccttgttccc aaataaacat cacgactaag atgatcaaac
     2401 caatcagaac ggctacaaaa ccgcctcgga agaatttgac aacacttgag ataaagaaaa
     2461 cgacttctat cgcaccgaag aaaaaggtaa ctaaatatgc aagccaacga gaatgcccat
     2521 tttggataag ataaaagtaa agcagtgctg ttgtcatcaa catcgtcaca gtgatcgata
     2581 gaccgtaagc agcttccata tgatgagacg ttcggaatgt gacaaccact agagaacagg
     2641 cgatccataa aatcagattg actgctggga tatacatttg cccgatactg ttcccaggat
     2701 acatgatctt taaccgaggc agcagtttca acttgattgc ttctgaaact agcgtaaacg
     2761 aacctgtaat caatgcttgc gaagcaatga ctgcagcgac tgttgcaaaa gcaacgccga
     2821 tcacgatcca actttgaggc atcatttgga agaatggatt caggttcttg atttgctgtg
     2881 cttcagggtt ttgataaaca ttcaacaacc acgcagcctg cccaaaataa ttgataacca
     2941 aacaaatttt gacgtaaggc cagctcagac gaatatttcg tttgccgaca tgtccaagat
     3001 cggaataaag cgcctctgca cctgtcgtag ccaggaaaat atttccaaga atgaacaagc
     3061 ctaatttgtt atctgcacta aaaagcagct ggatagcata ataaggattc agtgcacgga
     3121 taactgtcca gtcttgactg aagttcatta atcccattac gcctaaaaaa gtaaaccaag
     3181 cgaacatgat tggtccgaat gcttttccga caatatctgt accaaagcgt tggaccatga
     3241 ataaaacaaa aataataact aaagtgataa tgacgatcac gttctggtta ttaccgaacc
     3301 ggtcaaaaaa ctgcggaatt cctcgcaagc cttcaatcgc agtcgttacc gtcacagcag
     3361 gggtcaatac cccatctgct agtaaggcag ctcctccgat cattgcagga atgatcaaat
     3421 atttcccacc ttttcggaca agtgtgtaga gtgagaaaat tccaccttca ccatggttat
     3481 ctgcattcaa tgcaatcacg acatatttga ttgttgtcag tagagtcaat gtccaaaaaa
     3541 tcaatgagac tgatccgata acaaaatcag gattgattcc tgacaatccg ccattatctt
     3601 caacaatcga tttcataacg taaagcggac ttgtcccgat gtctccgtag acgactccca
     3661 tcgctacaag caggccagcc attgatatct ttttggtatt gtgcgttgtt gccacgtttt
     3721 tccctcattt cttgttatat ggatatcctt taggtaagct tgaatgatag atgatattct
     3781 tatccatgac acccgctttc ctaaattgct tctaattatc caagtaacac actgaagtgt
     3841 caacttattt gaataaaatt attctttctt tggacgttct ctgatacgtc ttgccacaaa
     3901 tgaataaaga gcaaggcaaa aaattgcacc caataatgct ggtatcaaat aaaaaccgcc
     3961 gagttccggt cccagtggtc ctagtaaaaa ttcgccgagc caactaccta aaaaaccgat
     4021 aatgatattt ccagatacgc ctcccgggac ttcctttcct aaaattgcgc cagctatcaa
     4081 acctaatata ccgccgataa ataacgacca taaaaaattc agcatctcct ttccctcctt
     4141 tatccatatt tctcactttt attttacgct ttattcagaa ggactccaaa aatatgcgcc
     4201 aagaaactcc agaaaaaaag aagttgtaac aaaagtgttc agcttatttc cgtagaagct
     4261 gcttctggaa caccgtgaat cagaggttgt gaaatcagcg gtttgacctg agtattagag
     4321 aaacaaacgg aaaaatagtt cctcatattt tgccgttttt tgagctaata tcgagggaca
     4381 gctgattgaa catcgtttat tggagaggtt gtaaaaaagc tgttctgcat caagtaataa
     4441 gaacagccaa gtaaaaacag ctcctaatgt ttttaacttg gctggactta ttaccgcaga
     4501 tgcaagcttt tgaacaccgt ttattcgaaa aaaaaggact gtgacacggc ttttgtcaca
     4561 gtcccctttt ttcgaataat tattgtcccc ctgtcacctt cacgatcaca agtacattat
     4621 tcctatgaat taaattattt ttcttcattt ttcgttgaac catcttcgtt caacattgct
     4681 tttcttgaca gatttacgcg tccttgttta tcgatttcag ttactttcac aaggatctca
     4741 tcacctagtt taacaacatc ttcgacttta ttgacacgat cgtttgctaa ttgggaaata
     4801 tggacaagtc catcttttcc tttgatcaag ttgacgaatg caccgaattt ttcgatacgg
     4861 acaactttcc ctagataaac ttcaccaact ttgacttctt tggtcaaatc ttcgatgatc
     4921 ttgatagctt ttttgatcat ttctgcatca gctgaagcaa tacttacttt tccatcttga
     4981 tcgatatcga ttttcacacc agtttcatcg atgattccgt tgatcgtatc gccgccttta
     5041 ccgataacat ctttgatttt agcaggttcg atctggatca tttcgatttt tggtgcatat
     5101 tggcttaatt cttcacgtgg agcagcaatc gttgaagtca attcttctaa gatttccata
     5161 cgtgcttgtt ttgcttgagt taatgcttca gttaggattt gttctgtgat tccttgaatc
     5221 ttgatatcca tctgtaaagc agtgatacca tcttttgtac cggcaacttt aaagtccata
     5281 tcgccaagat gatcttccag cccttggata tcagttagga tcgtatagtt ttcaccatca
     5341 gaaacaagtc ccatcgcaat accggcgact ggcgctttga ttggtacacc tgcatccatc
     5401 aatgctaatg tgccagcaca gatacttgct tgggaagaag aaccatttga ttccaatact
     5461 tctgctacta aacggatcgt ataaggaaat tcttcttctg aagggattac ttgtgctaac
     5521 gcacgttcac ctaatgcgcc atgtccgatt tcccgacgcc ctggagagcc tgcacgtcct
     5581 gtagaaccaa cagaaaattg agggaaattg tagtggtgga tgaatcgttt gctgacttcc
     5641 acccctaaac catcaatgat ttggtgctct cctagaggtg cgagtgtaca agctgataaa
     5701 gcttgtgttt gtcctcgtgt gaacaaacct gatccatgta cacgtggcaa taagctgacc
     5761 tctgatgaca atggacggat ttcatccaat ttacgcccgt caggacggat cttatcgatg
     5821 gtgatcaatt cacgtacgac atctttttca agatcttctg tgatttgttt aacttctttc
     5881 aacaagtgat cttcatcttc atgacctgca aatttctcag cataagcttc gcggatatcg
     5941 atcttcacct gctcgatatt atcttcgcga gcaagttttt cttcagtcat tactgctgct
     6001 ttcattgtag cgtaagaagc atcaaagatt tcttttttca atacttcatc aacttgcagt
     6061 aaagtcactt ccattttttc tttccctact gcttgaacga tttcttcttg gaaagcaact
     6121 aactctttga tagcgtcaaa accaaacagc aatgcaccaa gcatgtcttc ttctgaaact
     6181 tctttcgcgc cgctttcaac catattgatg gcttgtttcg ttccggcaac agtcaattcg
     6241 atatctgttt gttctgcttg ttctactgtt ggattcaaga cgtactcgcc atttacacga
     6301 ccaacttcta cgcctgcgat tgggccgtca aatgggatat ctgagattga tagtgctaaa
     6361 gaagaaccta gcattgctgc catagctggc gagcagtctg tttctacact catcacgatg
     6421 ttcgttactt ggacttcatt acggaagcct tctgcaaaca tcgggcgaat tggacggtcg
     6481 atcaaacggg cagtcaatgt tgcttccgta cttggacggc cttctcgttt gatgaaacct
     6541 ccagggattt tccctgctgc atacattttt tcttcataat tgatcgttaa tgggaaaaag
     6601 tctgtatctt ttgcttcttt agaggccaca gctgcactta agactactgt atctccataa
     6661 cggactaaaa cggctccgtt tgcttgtttt gctagctgac cgacttcgat ttgtaaggga
     6721 cggccgcccc atgtcgtttt gaatacttgt ttttctgaca taacttctcc ttttccttct
     6781 cgtgaaagca agacgctact aaacaaatga aaactgccga aagccgtctt ttgagcagct
     6841 ttcatttggt tagtaggagt ccatctagct tgatcacgga attttactta attgatatac
     6901 gagtaaaaaa agtgagattc atgtgaatcc cactcttttt gactaaaatt aacgacgcaa
     6961 gcctaaacgt ttgatcaatt cgcggtaacg ttgaacgtca gttttacgta agtaagctaa
     7021 caagttacgg cggtgaccaa cttttttcat taggccgcgg tatgaatgat ggtctttttt
     7081 gtgcacgcgt gcatgttcat tcaagtggtt gatttcttca gttaatacag cgatttgtac
     7141 ttctggagaa ccagtatccc cttcatggcg agcgtattcg ttgatgattt cattcttgcg
     7201 ttcttttgaa attgccattt ctttcacctc tttcgattat tcccctgcga ctgagtaaaa
     7261 cgttggtgat tcgcttaacc aagtggcagg tcatgtgcct agagcacaca gctatacttt
     7321 acctgaaacc gggttgaaaa tcaagtagtt aatcattaag aaaaggtagt tttcaaacaa
     7381 tcttactact acttttccat ttttgtggta aactataatg cgaaaataga cttgaaacac
     7441 agtcttttaa gaaaggggta catattccat gattacaatg gatgatatca ttcgtgaagg
     7501 aaatccgacc ttacgcgaag ttgcaaaaga agtttctctt ccattaagcg aagaagatat
     7561 ctctttagga aaagagatgc ttgagttctt aaaaaacagc caagatccaa tcaaagctga
     7621 agaactacac ttacgaggcg gtgttggctt agctgctcct caattagata tttctaaaag
     7681 aatcattgct gttcacgtac caagtcctga cccagaggca gatggacctt ctctaagtac
     7741 tgttatgtat aatcctaaaa ttttgagcca ttctgttcaa gatgcttgtt taggggaagg
     7801 tgaaggctgt ttatctgttg atcgagaagt accaggatat gttgttcgcc atgccaaaat
     7861 cactgtgtct tattatgata tgaatggtga aaaacacaag attcgtttga agaattatga
     7921 atcgatcgtc gttcaacatg aaatcgacca tatcaacggt gtgatgttct atgaccacat
     7981 caacgatcaa aatccatttg cactaaaaga aggcgtattg gtgatcgagt agagaattgg
     8041 caggttcctt cgatactatg ctacaagaaa gctttataaa aaaggggagt gctcaaaagc
     8101 tgcacttccc ttttttatgt ttctccacta atcgaaattt agatagacat ctagaaatcg
     8161 caattccaaa aaattctgtg tattggatac gcatcttttc ttattttttc ttatttcttc
     8221 catatgggtg tttatctcag agatgataga atagtttcta ggataaaaag tagcagctac
     8281 gatgttatcc ttcgtagagg attcctgctt cagctagttt ttgtttgatg tttttcagca
     8341 tatgcttttc tgggtagcgg atcgtatgca gatggatgcc gcctgttaat tcggataaca
     8401 aagtagcatt acttttttga taacgtctca taaaggaatc gatatcttgt ggcgttttga
     8461 tgtgcaaagt tcctgctaac tcaccgtaaa ggggatgttc cacaattaca tcaatgattt
     8521 caccaccatt ttcaacgatt agtctcagtt cttcttctgt ttgatctttt ccatgctgga
     8581 cagcgatttt actgatgtgc ccagtattgg tttcttctgt ttcgaggata taacctcttg
     8641 ctgttgccac gatactttta cctgcagctc gtagtaaagc aatatcgcct acaatgatct
     8701 gacggctgac tccaaaagtt ttcgcaaact tgctagcact cactggtttt tctgtatttg
     8761 ccaaggtttg catgatttgt tttcgccgtg tctctccttc gatcacactt attcctcctt
     8821 cattttgttt tggtattcgc gcgagtgttt catcaaatca acatacgtgt ctgttattgt
     8881 ttccttatat cccttatttt tcagcagact aacaacttta tccaatactt gctgctctct
     8941 ttttgcatca taaactgctt ggttttcttc ttttttcact tgtcctattt tagttaccgt
     9001 atccattctt ttttctaata aagcaaccaa ctctcgatcg atcatatcga tcttatgacg
     9061 taatgtttca agagactctt ctgttagttc ttcctctact gtcttgatga tacgagcagg
     9121 atttcctgca atcactacat tgtcgggaaa agatttggtc acaaccgaac ctgcgccgac
     9181 tactacgttg tcccctagag tgacacccgg cgtgacgata actcctccgc ctaaccaaac
     9241 attattaccg attttaatgg gttttgcgta ctccagaccg ctgttacgtt tcactggatg
     9301 tagtggatgc gtcgccgtgt aaagctggac attcggagcg aacatgcagt tatcaccgat
     9361 ttcaatcgtg ctgacatcta aaaatgtaca attgaaattt gcataaaaat tctccccaac
     9421 aaatatatta tatccgtaat caaaattgat aactggctcc atatagattt ttttccctgt
     9481 acggccaaaa gtctctttca acaattggga tcgcagttcc gctgattctg cttggttgat
     9541 gatttggctt tgacttcttg caaacatacg gtcggcaacc agctcaggat cattggcaaa
     9601 ataaagctcg cctgcaatca ttttttcttt ttcggttttg aattcagtca taatctgctc
     9661 ctaattcttg tatttttttg aaaacaaccg ctccgtcttc ttgaataaac gtataaggct
     9721 ccgctaaata aacaggcgtt tgattgatta ctaagatttt ggctgacggc tggcgaaact
     9781 gtaccagatc acaaaacgga tgaacttgaa aactcgttcc aacaatgacg atcagctctg
     9841 cttggctgac ggcataagcc gcctgctcca tgactccatc ttgaaaccct tcaccatata
     9901 acacgatgtc tgggcgtatt tgtcctccgc atgcttgatg tttgtcgctg tgaagatatt
     9961 ctttccagtc taccgtttgt tgacattttc gacaatgaca ttgatacaga ctcccatgaa
    10021 aattgacgag ttgcgggctt ttagcctttg cgtgcaaacc gtcgatgttt tgggaaacaa
    10081 cccaaacatt tttttctttc gctagatgtg ctatttccaa atgaatgata ttgggttttg
    10141 cttcaggatg ataaatcttt ttgacaaatt gatagaattt atccggttca ttcaccattg
    10201 cttgatgact cagcaagtat tccggctgct ccatcccgtg gtagattcct gacaaagatc
    10261 gatagtctgg cactccagaa ggtgtggata cccctgcacc ggtcaaaaat gtaatttgct
    10321 gataagctaa tatctctttt gctgcttcgt ctactgttaa ttgtttcatg ttttgtcacc
    10381 tcactttcca ttatagccca tactcgaaca aatttattgt tgaaaagtca gaaaaatggg
    10441 aataaaaaag tgttatgggc atttgagcaa tttatcacaa tgttcactga caaaagaatg
    10501 aaaacgtgtt acaatactgc tgtataaaag tgaggtgaat cgatatgtta ccattcttta
    10561 tttattgggg cgttattctg gcttgtatcg cctggttagc gttaagcgtt tatttctctg
    10621 ttttttatct tgtacgcaaa gaaaatggaa atctttgggc ttttgcttta ttcaacgtga
    10681 ttgccgcaat tgttttagcc attacattag ccgtatatcg aacatggggc tggggaatca
    10741 cccaatactc aagtttgatt tatctaatat tagccattta tggcgtcgtt gttcttttgc
    10801 aagcgatcct aggacgtgag ccaaagaaag cggcagctta aatgatcgag atggaactgg
    10861 acacaggaaa ttttctgttc tagttctttt tttattgtat tacatacatt tttgtgtata
    10921 attatactat cgtttgcaat ggatagatga ttcacatttt gattgttttt tcggtaaaag
    10981 taaagatttc tatatttatc agtatttttt caaaaaccag cagttataga ttgacaaagc
    11041 ctctcgagta tcgtaaactt tttttgtata aataactgaa tacgagatgc ctcaatcaat
    11101 gaggtagagg tcgcgagaat cattaaccct gtggagtgaa gcaaacatgg agaagcagga
    11161 atagggagga tcgccgaaat gtgcactttt ttgcttggag tgtatgttgg gacgcaagtt
    11221 aagagcttgc ggactgtctt agcagtgatg ctaagttgcg ctatgttttg tgagaggttt
    11281 atcaccttat ggaattttag cggccttttt atatctataa atcggtcgct ttttattttt
    11341 tcagataaag ctttaccgca tttcatctag accgctcgtg tatcatataa tcagaaaggg
    11401 agaaaaaaat gaaaaaaaat atggtttcag ttgccgtact atttgctttt gtcttctcac
    11461 tattcagtgt gggatctctg gcaaatgcag atgaaaaaac accgagcgat gagtttcgcg
    11521 taggtatgga ggctgggtat gcacccttca actggtctca acaaacagat gagaataatg
    11581 ccttgccaat tcaaggccaa aatagttacg ccggcggtta tgatgttcaa atcgctaaaa
    11641 aagtagcaga tggtttaggg aaaaaattag tcatcgtcca aacgaaatgg gatggtctgg
    11701 ctcctgccct tcaatcaggc aagatcgacg cgatcatcgc cggaatgagc cctactgctg
    11761 aacgacgaaa agaaattgat tttaccgatc cttattacga atcacaatta gtagtagtag
    11821 ttcaaaaaga tagcaaatat gcaaaagcaa aaagtttagc agatctttct ggagcaaaga
    11881 tcactgctca gttaaataca ttccactata ctgtgatcga tcagatacca gatgtgcaga
    11941 aacaacaagc aatggataat ttctcagcaa tgagaacagc tttagcttct ggaatgatcg
    12001 atggttatgt cagcgaacgt ccggaaggtg taacggcaac tagtgtgaac aaagacttgg
    12061 aaatgcttga attcagcggt gcagatggct tccagacaaa cccggaagat gttcagattt
    12121 ctgttggtat gcgtaaaggc gacccggata tccaaaaagt aaaccagatt ctttctggca
    12181 tctctaacga tgaacgaacc aaaattatgg accaagcagt caaagatcag cctgctgcaa
    12241 ctgatagtga agaaaaacct ggcatcattt ctgatttcac tacgatttgg aaacaatacg
    12301 gcaatatgtt cttacgaggt gctggactta ccttgttcat cgcattgatc gggacagttg
    12361 tcggtactac acttggatta ctgattggtg tcttccgttc ggtacctgaa tcaggaaatg
    12421 cactgactcg cttcttccaa aaaatcggaa atgcacttct ttctatctat gtcgaagtat
    12481 tccgcggaac accgatgatg gtacaagcaa tggtcatctt ctacggtctg gcactcgctt
    12541 ttggcatttc attgaaccga acgattgccg ctttgtttat tgtctctctc aatactggag
    12601 cttacatgac agagatcgtt cgtgggggga tttttgcagt agatgaaggg cagttcgaag
    12661 ctgcgcaagc cattggtatg acccatggcc aaacgatgag aaaagttgtt attccacaag
    12721 ttttacggaa tatcttgcca gcaacaggaa atgagtttgt tatcaatatc aaagatacag
    12781 cagttttaag tgtaatcggc gtagctgatt tgttcttcca aggaaactct gcttccggtg
    12841 cgaatttcca attcttccaa acatttacga tcgtcgggat catctactta gtcatgacct
    12901 ttacgatcac cagaatcctg cgggcggtag aaaagaaaat cgatggtcct tcagcttata
    12961 ccaagcttga agaaatcgac aattcaaatt tgcaggaata aggaggaaga atcatgaatg
    13021 aaaaaattat tgaaatcaaa catctaagaa aaagcttcgg tgaaaatgaa gtattgaaag
    13081 atatcagcgt aacagtcaat aaaggtgaag ttgtgacgat catcggttct tccggttctg
    13141 gtaaatctac tttcttgcgc tgtatcaatt tactggaaaa accaacaggc ggcgagatca
    13201 tttataatgg agaaaatgta ttagctccta aatataattt acctaaatat cgaacgaatc
    13261 taggtatggt tttccaatcc ttcaacctgt tcaacaatat gaatgtcttg gaaaactgta
    13321 tgtctggtca aacaactgtc ctgaaacgag ataaagaaac tgccaaaaaa gtagcaatcg
    13381 aaaatctgga aaaagttggt atggatcgtt atatcgaagc caaaccagca caattatctg
    13441 gtggacagaa acagcgtgtc gcaattgctc gggcattatc aatgaatcca gatgtattgc
    13501 tattcgacga acctacttcg gcgttagacc ctgaaatggt tggcgaagtg cttaatacga
    13561 tcaaagactt agcacatact ggcttgacaa tgcttatcgt gacgcatgag atggaatttg
    13621 caaaagatgt atctgaccgt gtcattttta tggataaagg tgtgattgca gaagaaggta
    13681 caccagaaga tatctttgtc catccgaaag aagaacgtac aaaagaattc ctttcacgta
    13741 ttttaaatgc ttaggatcaa tagctgattg ggacaaagag ctgcggtgtt taccgcagtt
    13801 cttttttatg aattactcat aaaaggtaaa tttctgaaaa ttttggaatc ttagttgtgt
    13861 ttttcagaaa actctcttaa tatggaagta attaaacttt tttagttagg atgatttaaa
    13921 aatgaatgaa gagcaagaac tgcagcgtgg actgaaaaat agacatgtcc aactgatttc
    13981 tattggcgga gcgattggaa cggggttgtt tttaggttcc ggaaagtcta tccagctagc
    14041 tggcccttcg atattgctcg cctatcttat tactggatgc atctgttttt tcattatgcg
    14101 tgcgttaggc gaacttctgt tatcaaacac caataaccat tcttttctgg attttgttgc
    14161 agaatatctt ggcaaaaaag cggctttcat cactggctgg acgtattggt tctgctgggt
    14221 atcgattgca atggccgatt taacagccat cggaatgtat gtacgctact gggcgcctgg
    14281 tgttcctcag tggcttcctg aactgattgc attaggtctt cttctttgct tgaatatggt
    14341 ggctgtctca ttgtttggtg agttagagtt ttggtttgca ttgatcaaag ttgtagcgat
    14401 cattgccttt atcctcgtag gagcttatat gatcctcacc cactatacga cagatattgg
    14461 cacagccagt atcacgaatc tatggtctca tggcggattc tttccaactg gtgcaaaagg
    14521 atttatctta gctttccaaa tggtaacctt tgcttttgct gggatagaat tagttggatt
    14581 agtcgctgga gaaacagaaa atcctgaaaa agtgttgccg gaagctatca ataatattcc
    14641 tatcaggatc atcttatttt acttaggatc tctttttgtc attatggcaa tctatccatg
    14701 gaacagcttg aatccagata acagtccatt tgtagaagta ttttcggaaa ttgggatcac
    14761 gattgctgct tccttgatca atttagtcgt attaagtgca gcagcttctg cctgcaacag
    14821 tgcaatatat agtacaggac gtatgcttcg ttctttagcg caagaaggca gtgcccctaa
    14881 aaaattcaaa aagttaacaa cacatcatgt gccagggaat gctttgacat tttctactat
    14941 cgtcattttc atttctgtta tcttgaatta cgtgatgcct agtgaagtat tcacactagt
    15001 aagcagtatt gccactactt gtttcttgtt tatctggagt atgcttgtct acacgcacat
    15061 gaaatatcgt aaaagtatcc tcggcaaaaa agctcattca tttaaaatgc cgttgtaccc
    15121 atttagtaat tatctggtat ttctttacat ggcctttgtg tgtgtcgtct tgttcctagg
    15181 aaaagatacg agaatcgctt tattactaac acctgtgtgg ttcttgcttc tattactaat
    15241 ctatcatatg aaatatgaac gtaagaagta agaaagtagt tgtgacagaa gtggtcagct
    15301 tcgagaaata agaaggaatt tacgaaaatt gcttcttaaa tttttgtgaa atttcggctt
    15361 atttcttgga gataaaagct tctgtcccag cctcttttct atttccccgg aaacaaccgc
    15421 tgataatagg catctgcttt tttataggaa aaaatccaaa taccagatac aaaaaaacgt
    15481 ccgaataacc cgatcaacgg tacaaaaaag acaccggcaa tcaagcataa gttaatcatc
    15541 atggagataa gacttcgacg gtcctttgac aaaactctca cgacatggga atctggttta
    15601 tttgctttca tgatttgcct catcaagata ccaaaagaaa aactccacat cgtgtatact
    15661 aagacataag ccatctcagg ccaaaaagct tcagggttac gcccgaccca actagtaaca
    15721 gaaggacata aagtcagcca aaagagcaaa aagatattcg accagaccac tcggtaatta
    15781 attcgttctg ccatctgaaa tatacgatga tggttcaccc agatcaccgc aacaaatata
    15841 aagctgatgg tataagctaa taatgtattt cggatgaccc ataaagaatg aaagctagat
    15901 gtattaggga tcttgatctc taatacaata actctcaaaa caatggctac cactccatca
    15961 gtaaatgctt ctaatctcga ctttgtcacg atgattcctc ctcagatgat tcagcgcttt
    16021 tattttatca cttacgttat taaataacca tcgttttata tagggaattt tctgaaaatt
    16081 gttgcatatt tttcgaaatt ttgttacttt taaaaaaacc gtaaaggagt tatgtatgac
    16141 aaaaaaatta tcatttaaag actatctttt tataggctcc atgcttttcg gtctattttt
    16201 tggtgctgga aatcttatct ttcccgttca tttgggtcaa gaagcaggcg ctgctacctt
    16261 ttgggcgaat ctaggtttct tggttaccgg tatcggtctt cccttcttag gggtgattgc
    16321 cattggtgta tcgaaaagct caggtgtata tgaattagca aaacggataa atcaaacata
    16381 tgcgatggtt tttaccatct tgctttactt agttatcgga ccgttttttg ctttacctcg
    16441 ccttgcaacc acatctttcg agattggttt agcaccattt atcgatccta gcagacagac
    16501 gctatatcta gcaattttca gtattgtatt ttttgtgctg gcttggtggt tttcaagaaa
    16561 accgacaaag atattagatt atgttggaaa gttcctgaat cctgcatttt tggttttatt
    16621 aggtgctttg cttctccttg cttttttgaa tccactaggt tctgtaaatc aagcgcctat
    16681 tcagccaaat tatcaagagc atgctttttt cacagggttt actcaaggat ataacacatt
    16741 agatgcgctt gctgctttag catttgggat catcattgtc acaacaatcc aaaacatggg
    16801 tgtaacaaaa cctgctgaaa tcgctaaaga cacgatcaaa tctggtgcga tcagcattat
    16861 attgatggga atcatttata ctttgctcgc ttatttaggt gctatgagct taggtagctt
    16921 tgctctaagt gaaaatggcg ggatcacgct ggctcagatt gctgatcatt atttaggtac
    16981 ttatggcagt atcttattag catttatcgt tatattagct tgcttgaaga ccggtattgg
    17041 tttgattaca gcttttgcag aaacattcac agatttgttt ccgcaaagaa attacgcatt
    17101 ctttgttgca cttgctagta tccttccttg tttagcggca aacgtaggct tgacgaatat
    17161 cattcaattt tcgttgcctg ttttgatgtt catctatcca ttagcaatga cactgatttt
    17221 actagtgtta gttggtcctt tgtttaagca gcgtacggct gtttatcgaa tgactactta
    17281 ttttacattg attgcttcga tttttgatgg gttgaacgct tgcccagaaa ctatcaaaca
    17341 aacacctatt gttcaaaatc ttttatatgt tgcggaaagc tacttgccgt ttttcaaatt
    17401 ggggatgggg tggatcgtac cagcagttat cggttttgtt atcggactga tttggagttt
    17461 cgctaagaaa gaagaagtag cagattgata aaagaggttg tgaaagagac gttcagcctt
    17521 gagcaataaa aagtaatttt gaaaaatggc ttctcacatt tttgcataaa tttgacttaa
    17581 taccgagaaa ctgacttttg aacaccgttt attgagaggt cgtgaaaaag ccgcttagtt
    17641 tcaagtatta agaaatattt tgtgaaaatg gcttctcaca tttttgcata aatttgactt
    17701 aataccgaga aactggcttt tgaacaccgt ttattgagcg tctataaact gacctgagta
    17761 ttagagaaac aaaacggcaa agtagctcca tatactttgc cgttttgttt tgaactaata
    17821 ccgaagagaa gctgatcaaa caacatttct tttataatat agattttaga catatatatg
    17881 atataaaaat agttttcgca aaa
//
LOCUS       DARPZF010000050        17106 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.052, whole genome shotgun sequence.
ACCESSION   DARPZF010000050 DARPZF010000000
VERSION     DARPZF010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17106
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.052"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            7..1398
                     /locus_tag="SLE65_002159"
     CDS             7..1398
                     /locus_tag="SLE65_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEI8449431.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIETSGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            1414..2454
                     /locus_tag="SLE65_002160"
     CDS             1414..2454
                     /locus_tag="SLE65_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEI8449432.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            2473..3558
                     /locus_tag="SLE65_002161"
     CDS             2473..3558
                     /locus_tag="SLE65_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEI8449433.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            3591..4553
                     /locus_tag="SLE65_002162"
     CDS             3591..4553
                     /locus_tag="SLE65_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HEI8449434.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            4546..5979
                     /locus_tag="SLE65_002163"
     CDS             4546..5979
                     /locus_tag="SLE65_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEI8449435.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKGELI"
     gene            5976..7046
                     /locus_tag="SLE65_002164"
     CDS             5976..7046
                     /locus_tag="SLE65_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449436.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            7033..8454
                     /locus_tag="SLE65_002165"
     CDS             7033..8454
                     /locus_tag="SLE65_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEI8449437.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            8467..9474
                     /locus_tag="SLE65_002166"
     CDS             8467..9474
                     /locus_tag="SLE65_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEI8449438.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            9486..10490
                     /gene="neuB"
                     /locus_tag="SLE65_002167"
     CDS             9486..10490
                     /gene="neuB"
                     /locus_tag="SLE65_002167"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HEI8449439.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            10487..11635
                     /gene="neuC"
                     /locus_tag="SLE65_002168"
     CDS             10487..11635
                     /gene="neuC"
                     /locus_tag="SLE65_002168"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HEI8449440.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            11608..12285
                     /locus_tag="SLE65_002169"
     CDS             11608..12285
                     /locus_tag="SLE65_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEI8449441.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            12275..13417
                     /locus_tag="SLE65_002170"
     CDS             12275..13417
                     /locus_tag="SLE65_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEI8449442.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            13430..14407
                     /locus_tag="SLE65_002171"
     CDS             13430..14407
                     /locus_tag="SLE65_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEI8449443.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            14407..15315
                     /locus_tag="SLE65_002172"
     CDS             14407..15315
                     /locus_tag="SLE65_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HEI8449444.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            15316..16068
                     /locus_tag="SLE65_002173"
     CDS             15316..16068
                     /locus_tag="SLE65_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HEI8449445.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            16073..17020
                     /locus_tag="SLE65_002174"
     CDS             16073..17020
                     /locus_tag="SLE65_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HEI8449446.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         6163 a         2190 c         3090 g         5663 t
ORIGIN      
        1 gtatatatga ataaaaatgg agaatggagt gctgcacgac ggatattcat tatattaatg
       61 gatgttattg tatacaatgc agcaatatat agtagtttct tactgaagtt tcgtggagag
      121 atcccattac gaaatttaga aactttccaa cactcagcaa ttattatttc agtgattttt
      181 attgcgttga acattttgtt gggtgcatat gttttttata atcgaatgat cagtgacatc
      241 gtgtttgtca cagtcatcgg tcaggtattg atgacactag ggatcatggt agtgactttt
      301 gcgggccgct ggtttgcttt tccacgtctt gttatcttac tttcatttgt tctcggtacg
      361 cttttcttaa gtatctatcg tattctcgta tataaacttt atttacgcgt aagtcgagat
      421 aaaaaggtcg tcattattgg gttagaaaag gatgtcgcac cagcaatcca aaattttggt
      481 tcaaagaaaa acaacaaaca taaagtcgaa gcagtcattc ttgataacta ttatgcaaac
      541 atcaaaaata tgattaaaga catcgatatt gtctatcttg cttctcatat cgaagaaact
      601 gaaaaaatca aaatctatca attagttact aaaaatgaaa aaaaattgtt tttgaataca
      661 acatttgaaa acttgacatt gatcaatcca aatattatga atttcgaaga tgaaagtatt
      721 attgaaacat ctggatttag aatccaacct gaatatgaac tattcaaacg tttgtttgat
      781 atcatcgttt cacttgtttt attagttatt gcttcaccat ttatgttatt cacagcaatt
      841 ttagtcaaag tgacatcacc gggaccaatc atctataaac aagtgcggat cacaaaaaat
      901 caaaaggaat tttcaatcta taaattccgc tcgatgaccg ccacagccga agcaaaatct
      961 ggaccagttt tagctaagag caatgatgca cgagtaacgc ctgtaggtaa atttattcga
     1021 gctgtccgct ttgatgaatt accacaaatc ttcaatgtgc tgaaaggcga tatgtcgatc
     1081 gtaggaccac gtcctgaacg tcctttcttc gtcgatcagt tcaatgcaga aaacccttat
     1141 tactacttac ggcataatgt tcgtgctggt atcactgggt atgcacaagt ctatggaaaa
     1201 tatgtctctg attacaacag taaattacgt tttgatttac tttatatcaa aaaatattca
     1261 ttgatgcttg atttaaagat cttgctgcaa accatcaaga tcctatttga taaaatgtcc
     1321 tctcaaggac ttgaagaaga cgaaaatgtg atctcattgg cagaaattgc ttttccgaat
     1381 gaaaaaatct ttcgctagtt gggaggcgta aaaatgaaca atccgaaatt cagcataatc
     1441 gtaccagtat acaatgcaga agcaactatt ggtcgaacga ttgatattct aaaagaattg
     1501 gattatgaag agtacgaagt cgttttagta aatgatggat caacagatca aacacaggaa
     1561 atcattcaag aactgattga aaatgatgaa cgttttgaat tgattactac gaccaatcaa
     1621 gggcccggat tagcaagaaa cgaaggaata agacagtcaa aaggagaata tctcttattc
     1681 ttcgatgcag atgacacgcc agtaaaaacg atcttgtcag attatgatca tttgctagaa
     1741 aagagtccaa aagcggatct tgttgttagt tcgtttgttt ttcgtacaat ggacgaggga
     1801 agaatcgttt ccgaaaaaga aaacttagtt acagaatgtc actatctaac tcacgaagag
     1861 tttataaaag acatgtatca gttaatgaat gaacagttga tgtatgttgt atggaacaaa
     1921 tgctatcgta gcgatattct gaaaaataac caaattctat ttaaaactta taatagttgt
     1981 gaggatcgaa tatttaactt acattattat gaatactgtc atcaagtgat catgaaccca
     2041 aaagtagaat atatttatga atttgaaggt gggaagggga tcactaatca ataccgacct
     2101 aacaagttcg aaacatttaa agaattctat tcattagcaa atactgtaac agacgatatt
     2161 aataaagacg gtatggcggc gcttctttta aaagggacaa cttcagttat tttttctatt
     2221 tatagtacct ctgcaagaac ttcaaaagag aagaaagacg aagcaaagca gatattgagt
     2281 gatccagtga tccgagaagc caagcaaatt gctaagacgg attcttcagc aaaaaaaata
     2341 acaaagttgc tttacaatat gccagctcca ctatttttat ctgctgtaaa agttggaagc
     2401 ttcgttgaag tgaaaatgcc agggttaatg gctgctttga agcgagtata ttagttaatg
     2461 gaggaaaata taatgaaaag aattttgcat tttcagggac gaatgggttt aggtggagca
     2521 gagtctttca tgatgaattt atatcgtaaa attgatcgta caaactatca atttgatttt
     2581 ttgatttatg aagattatgc agatgttcaa gactatcatt cagagattga aagattagga
     2641 ggccgtattt ttgttgtacc taatcctaag aaaaatattt ttaaatattt aatagaagtg
     2701 aataagttac taaaaaaaga atctttttct atagttcaca atcaggttta ttttggcggg
     2761 ggaattaatt tatggttagc caaaaagaat ggaatcagac agagaattgc tcatagccat
     2821 gcaactgaag atggaaaatc tcaaaatatt gtaatgaatg tattgcgtaa atttttaacc
     2881 aaattgttgt tacaaaatgc aacagactac cttgccgtta gtcaagaagc tggtgaaagt
     2941 ctgtttcaaa accatccctt tgagatagtt cataatggta ttgatttaga gctttatagt
     3001 aaaaattcag aagctaaggt taataagaga aaagaattgg atatctcaat gagtactttt
     3061 gttgtgggaa acattggacg attagagaaa caaaaaaatc aatcttattt gttagagatt
     3121 tttttagaaa tactaaaaat gaattctgat tcttacttga ttttagtagg tgaagggtca
     3181 cttagaaata aactgaaagc caaagcagta gaattggata tagagaaaag agtaaaattt
     3241 ttaggagaaa gaaacgatat tcccgagtta ttatctgtga tggatgtttt tgtaatgcct
     3301 tctctttatg aaggtctgcc aatggttgga ttagaagcac aagcagcaaa attaaaatta
     3361 gtcttagcag atactatttc caaagataca aagttaacaa ataatgtgga ttttgtatca
     3421 ttagatgaaa caccacaaga atgggcaaaa aaagtaataa aagagccgta tgctaataaa
     3481 ataacacaag aactaaagag ttatgatgtt tcgtacacta ctgaacaaat ggagagtata
     3541 tatagtagag atcattaaaa atgttcaaga tattttagga gtgattattt ttgaaaatat
     3601 gttatttgat attggcatac aatgatattg gcaacttaaa gagattggtc aatcgattga
     3661 acgaaaatgc agtttttatt attcatatag ataaaaaaac tgatatagaa ccatttattg
     3721 aagcatttaa atcatatgat aatgttgaat ttttatgtaa taaaaaccgt gttaaaattt
     3781 attggggtgg tttttccatt gtacaagcag aaatcaattt agtaaagaga gcattacaaa
     3841 atgagaaata tttaaaatat gtattattat ctggtgctga ttatccaatc aaagataatg
     3901 agtatattta taattatttt aaaaagaata gttcagtgga gtttattcgt ggaatagatc
     3961 tagatcaaat taaacataaa gaattttatt ataaacatat agatgtatat caaaaacatg
     4021 attatcctag aattaatagg aataacacaa ctgcatttaa aatttttaga gctataatta
     4081 atcgttgtct gaggatgatt aaacttcccc caaaaattag acaccataaa tttgatttgt
     4141 atcatggttc tcaatggtgg gctttgtcga aagaatgcct aacagaatta atacaaatgt
     4201 atgaacaaaa tcaacaagac tacctgaatt ttaaaatagg tatgtttgcc ccagatgaaa
     4261 aattttttca tacacttttt tttaattcct cgttcaaaaa taaaaatgtt attggaggac
     4321 cagatttacc acttgaattg aaaaatattg aagaaactac tttacaaact tcgaaattag
     4381 caaatattca tattattgat ccttccatga acaaatggtt tgatgaaagg gatatagatc
     4441 aaataaaaga aagtgaaaaa ttatttgtaa gaaaagttaa atcggattac tctgataaac
     4501 tattaaatag aattgataaa gaaattttga aagttggaaa tatagatgaa tagaatagta
     4561 cctgttttag agaagagttt attaagtcga gatgcgtttc gagtaataaa tttaatcatt
     4621 tgtctgcttt attttatgcc tagtactttt aatgtaacta atatcccgat gaaaatagct
     4681 tttgcttggg gtggaattat agttttgtat gaggttttta taaagaaaaa tttttttaaa
     4741 atgcgttttt cttggctact gattggagca atgattagtt ttatcttaac tataatcatt
     4801 aacagagaaa attttttaat tccatctatt tataattttg gatatttgct gattactttg
     4861 atagtaattt ttcctgcaga cttttcacaa agtgaagagg aaaaaaagaa aaaaatggtg
     4921 tattttaata atgttttcat tatcataatt tttttagctg cgctaatatc tatctatcaa
     4981 tttatttttt tgatttctta tcatgtccca acaggaacgc caggattact tgcaagacaa
     5041 ggttttattg aacatcggtt atttggtgtc tatacaagtc caaatgttgg agctatgttt
     5101 ggatatactt ctattatttt aagtttaatt agtgtattaa tttcaaaaat aacaaaaacg
     5161 attcgtgttt tttatatgat gaattttatc gtacaaatat tttatattac actttcttcg
     5221 tctagaggtg cccaggtagt aatttgttct tttttagtat tatttctttt gttgtttgcc
     5281 aattcaaaat ttagaaagag cattagagaa gtactacctg taaaaatcaa atggatggta
     5341 agcatattat tagttctatt ggtatatttt tcttttggta ctaattatgc taaggatttt
     5401 ttagcaacaa ttcctgtatc gattgataga aaagtagaag ttatagagtc aaatgaatca
     5461 gataaaactc cacttccaga aaaagaagta atattacagc attctagtga taactccgaa
     5521 atttcagctg gtcgttttac gatttggaaa gctgcgctta aagttataag accaactttg
     5581 ttatttggtt atggagagac cgatttctat gggaatagcg atgcaaaatt tttgaaaaaa
     5641 gtagatcttg atactacaga tgtgaatgaa ctaaaaagag cacatggaaa catgcataat
     5701 ggatttcttc aagtacttgt atcaagtggt ataattgctt ttatatgtat ctatgctttc
     5761 tatgtgttaa atatctttag tttactcaaa acatttttta gaagtaaagt gaattatgcg
     5821 tttcttggta ttgttttaat ttttatacta tctattttta tagatgaaat ggtggaggct
     5881 catgtacttt tcaataagcg cgatgtcatt tcaattgttt tctggtatta tttgggaagc
     5941 atttcttact tgtatttaaa aaaaggagaa ttaatatgaa gacagctttc attgcttgga
     6001 ctcctttaca tttgattaat atattaaatg tttatcaaaa tttttaccga gaatcaaaag
     6061 gagatttatt tatttattct gaatttgaaa acgctagaag atatagtgag cgtataaaag
     6121 aattagggct atttaatgat gttgtttttg tgaatcaccg gaaaatcggt tcttccttta
     6181 aacgtaaaat taacttgtta actaaccata atcaattttt ctcggatgat ttatccgttt
     6241 atgatgaaat ttttatacag ggggaaaatt atttcacaaa aatacttttc tccaatgttt
     6301 acaaaaaaaa tccagatgta aaactaaatt atatagaaga tggtttgggt acttatttga
     6361 agaagagtat attttcaaca agtaaaaacg ttcaaagagt ttttaaaata ttaaataaaa
     6421 atagcatctt caaaaaaaaa attgacgatt attttgtcta ttgtccggaa ttgttacttt
     6481 atgatgtaaa aaatataaaa aaaattccca aaatagatga aaacagtaaa ttgatgaaaa
     6541 acatacaatc aatctttggg atagaagaag tttttgtcgg agataaatgt atcttttttg
     6601 atcaaccttt attatctgat ggttatggca tagatgaaac agatattttc gctaaagtaa
     6661 atagtatatt ttctggaaaa aaagaaactt taattaagct tcatcctaga gcaaggacaa
     6721 atcgttatgg tgaaaaaaac atattgaatt ccagtttacc gtttgaagtc ttgctacttg
     6781 aaaatgactt ctcttcaaca cttttgatta gtcctatatc tacaatttct ttttcaccat
     6841 ctatgatgtt tgaaaagacg atcaactcta ttatgttggc taaattaatt ttaaatgaat
     6901 atacagcatt atctgaagat aaaaaagaaa cattgacaaa tattgttctt ttctgtgaac
     6961 attataaccg tctatcagaa gaaaaaattt tactcccaga aaactgggca gaattaagaa
     7021 agttggtaga gtatgggatt atttaacaca ctttccaagt caaaattagt taagtccagt
     7081 ttctggtata ctatagggaa tttttttatt aagggaattt cattcataac tattcctatt
     7141 tttgtaaata ttactactca agcagaatat ggtttgatta ataatttcac ttcatttgta
     7201 tcaatttttt cgattcttgt tgggctaagc ctaaattcgg caattaataa tgcaagtttt
     7261 gactataaag atgacataaa tgaatttatg tcatcggtac tttctctagc tacactttcg
     7321 ttaattgtgt tcttattaat agggaacata tattttttgt tttcaaatgc tttttttgat
     7381 atgaaccaac ttgtatttaa tttgatgtta ttacaaagtt ttgctagttt tgtaattagt
     7441 tatatccagt cttattttac gattaacttt aaccatttta aatatttgat tttatctttt
     7501 atatctactt ttttgaatat tgcaatctct gtagctttga tgcagacatt atattttgat
     7561 gataaatatg ttggcagagt agtcggcgga acactgtcat ttgtgttgat aggtttagta
     7621 atttatttaa gaataatgat aaagggtgct catttttttg ataaaaaaca gtggagatac
     7681 gctttaaaaa tctctttgcc gctaatccca cattccttag caaatatagt tttagcacaa
     7741 ttcgatagaa ttatgattaa ttcttattta ggtcctgctg cggggggaat atattcctac
     7801 attagtaaca taggtattat tctaagcgta atatggatgt ctactaataa cgcctgggtt
     7861 ccatggttct atggtgagat gagtaaaaat aatgaaaaaa aagtgaagaa agttagtaac
     7921 tattatttag tagtctttac tttgattacg atgattgtaa tggtagtttc gattgattta
     7981 gcaaaattta tggctccgaa agactattat tctgggttat ctttagtggt tccgataacc
     8041 ttaggctatt tctttcagtt tttatatagt ttaccagtta atgctgaatt ttatgagaaa
     8101 aaaacatcgt ttattgcgat tggtacagta gcaagtgcta tagttaatat actattaaac
     8161 atgattttca tacctaggtt aggaataatt gctgctggat acacaaccgt atttacgtat
     8221 tttttacttt ttatttttca ttataatatc gctaaaaaaa ttacgaataa acaattattt
     8281 gacacaaaaa aaatatgtat cataataatt tttgtatcaa ttttttcttt gatacttcat
     8341 attttaatca atcaaatgtt gattcgttac gttttgacat cattattgat aattagttta
     8401 gttatatatt ttttaaagat taagaatcga attatagatg actataattc ataggaggag
     8461 atataagtgt ttaaaggaaa aacaatatta gtaactggcg gaactggttc cattggaagt
     8521 gaaattgttc gtcagctttt aaaatatgaa ccaaaagcta tcagaattta tagtagaggt
     8581 gaagaaaaac aattttatat gcaacaagag ctctcaaatc acactaattt gagattttta
     8641 attggtgata tcagagactc tcaaaggatt gattatgcat gtcgtgatgt ggatattatt
     8701 tttcatgctg ccgcaatgaa acacgttcca gcaagtgaat ataatcctat ggaagctgta
     8761 aaaacaaatg tgatgggaac tcaaaatgta atagatgcag cgatcaaaaa taatgtaaaa
     8821 cattttgtag gtatcagtac agataaagta gtgagtccta ctaacaccat gggtgcgaca
     8881 aagttattga gtgaaaaatt aataatagct gccaatcagt ataaaggaaa aacagaaaca
     8941 atattttctt gtgtaaggtt tggaaatgtc atggggtcaa gtggatctgt tattcctctt
     9001 tttagtaaac aaataaaaaa caataaagat attactttga cagatgttga tatgacacga
     9061 tttatgatgt caataccgga tgctgcaaga ttagttctgt ctgctgctat gaattcaaaa
     9121 tttggagaaa catatgtctt aaaaatgccg gcaatcaata ttttaacttt agctcaatca
     9181 ttaataaaaa tatataatga tacacatgat gaaaaatata gaggtgaaat aaaagttgta
     9241 ggtatcaggc caggagaaaa attatatgaa gagctaatga ctacagacga aattgaacgc
     9301 tcatatgaaa atgataaaat gtatatcatt ccaccacact atcatgctac tgacgaactg
     9361 tacaaagatt atgaaaaaat taaaatcact gcatactctt cagatgcaac agaattaatg
     9421 agtggacagg aatttattag aatcgcaaaa gagaataatg tcgtgacttg gtaaggagtt
     9481 ttatgatgaa atcagaagta tatgtaattg cagaaattgg tgtaaaccat aatggaagtc
     9541 tagatttagc tttagaaagt attgataaag ctaaagaatg tggagctaac gcggttaaat
     9601 ttcaaacatt taaaacgaat aagctagttt ccaaaaaggc tccaatggca aaatatcaga
     9661 aggataatct taaagaggac agttctcaat ttgaaatgct aaaaaaatta gaattatctc
     9721 aatctgattt tattagaata aaagattatt gtatacaaaa taaaattgat tttttgtcta
     9781 ctccttttga tgaagaaagt gcagactttc taaaacaaat tggtgtacaa ggatttaaaa
     9841 ttggctcagg agatttaaca aatttacctt ttcttagaaa aatagatatg tatgggttgc
     9901 cagttttatt atctacaggt atggctgata ttcatgaggt cagtgaggct gtagattgtt
     9961 tcatagatag tccagttact attttacatt gtacttcaaa ttatccggct agttctgaag
    10021 atattaattt attggcgatt aacacattaa aagaaatgtt cgggataccc gttgggtact
    10081 ccgatcattc attgggatat gatgttggta tttgtgctgt tgcgatgggt gctaaggtaa
    10141 ttgagaaaca ttttaccttg gataaggaac tacctggtcc agatcataaa gcttctttag
    10201 atcctcagga atttgcagat tttgtaaagc atattagaaa cactgaaata tttttaggtg
    10261 atggtgttaa gcgagcaatg ccttctgaac ttagtacaaa agaagtatca agaaaaagcc
    10321 tagtggtcac tgagaattta aatgtgggag atattcttac agagaaatct cttacaataa
    10381 aacgtcctgg aaatggaata gctcctaagt ttttatatca atatattggc aaaaaagtta
    10441 aaagaccaat aagtgcagat agtgttctgc ttgaggaaga tgttgaatga aaaaaatact
    10501 tatagtaagt ggaacacgag ctgattatgg aatatataaa cctgttgctg agaatttact
    10561 acaagataat tgggatgtat catttgttgt ttctggaatg catttatccc ataaatatgg
    10621 atttactaaa gaattgatct tagctgacgg atttagaatt agtggagaag ttcaaagttt
    10681 gtttttagag aacaataagg gaaacatggc tcggtctgtg gcattagaga taaatggttt
    10741 cacaaatata tttgaacaaa ctagccctga ttttgtatta ttactagggg atagaggaga
    10801 aatgttggca gctgcgatag cttgtttgta tcttggaatc aaaacagcac atattcacgg
    10861 aggcgaagtg tctggtactg tagatgaatc aataagacat gccataacga aaatagcatc
    10921 tgttcatttt gctgctacgg aaaaaagcaa agagcgttta ataaaaatgg gggaagattc
    10981 ttggagagtt tttcccgtcg gagctcctag aatagatact attttaaata atagattacc
    11041 tagttttaga gatataaaag aaaaatatca tctaaaattt gaaaagaaaa aatacgtttt
    11101 gcaagtattt catccagttg taaccgaact agaaaatata gaaaaacaaa ttttagcttt
    11161 gatcaattca atggaacaac aatctcaacc aattatttgc attttaccta atagtgatgc
    11221 tggtagcgaa attatcagaa aaatgtacca gaaatattta aaaacggata ttatttatat
    11281 tacgaattta gagccggagg aatacctgac tatattaaaa gagtgcaaat ttatgatcgg
    11341 aaattcttct tctgggataa ttgaagctgc atcattcaaa ataccagtaa taaatttagg
    11401 aaccagacaa aatggacgag aacaatctaa aaatattata aatgcaaatc taaatgaaaa
    11461 tgaaattgaa actgctttga ataaaataca agatcctcag tttataaaaa gcttgaaaaa
    11521 tgttaagaac atctacggtg acggcaacag ttctagaaga ataacaaaaa cattgaatca
    11581 aatattgaat gatggggaag atattaagtg gattcaaaaa caaatagctt attaaaatat
    11641 actagtgatc catacattat tattggggct ggcggacacg caaaagtcat tattgaaacc
    11701 ttaagattag aaaataagtt aatatatgga ttttttgatg ataagcaaaa taaaatgcaa
    11761 gatctgaaat atcttgggaa aataaacgaa ttgaatagct gggcggatag caaaaaaaaa
    11821 atctataaat ttattgtagc tattggtgac tgtgtagtaa gaaaaaagat tataaaaaaa
    11881 ttgaatatgc caagtgagca atatggaata gctgttcatc caagtgctat agtggcaaaa
    11941 gaaatttcaa ttggttatgg aactgttatt tttgcgaatg ctgtaattaa cccagatgct
    12001 gtaattggag agcatgctat aataaacaca ggtagcattg ttgagcatga ttgtagaatt
    12061 aataactatg ttcatttatc tccaggtgta tgcttagcgg gtggagtaca tgtaggtgta
    12121 ggaactcaaa taggaattgg ttctcaatgt atccagatga agaaaattgg atcttggtgt
    12181 atgataggcg cagggagcac tattgttaag gatattccct cacattcctt agcttatggc
    12241 aatccagcta aaattaagaa agaaggaatt aattttgaat tctagaattt tattatcaag
    12301 tcctcatatg ggaggaacag aagaaaaata tgttgctaag gcttttaaag ataattggat
    12361 agcgccatta ggtgaaaatg tggataaatt tgaagaaagt attacaaaat atactggttc
    12421 taagggcgga gcttctgcgt taagttcagg tacagctgcc atacatcttg ccttaagact
    12481 gcttaatgtt ggaaaaaacg atattgtctt tgctccttca tttactttta tagctacagt
    12541 aaatcctatt ttatatcaag gggctgtacc agtgttcatt gactcagaac ctaatacatg
    12601 gaatatgagc cctgttgcac tagagagcgc attagaagaa gctgaaagaa acaaccaatt
    12661 acctaaggca atcatcgtag tgaatttata tggtcaaatg gctgattatg aacgaatttt
    12721 agctattgca aaccaattta atgttccagt gatagaagat gcagcggaat cgttaggttc
    12781 tacttataag ggaatttcgt caggcttatt tgggacaatt gggatctatt catttaacgg
    12841 taataagatc atcacaacct caggtggagg agctctagtg tctagtgata aaaaatatgt
    12901 tgagcattca agatttttag caacacaagc aagagatcaa gcaccgtatt atcaacatag
    12961 cgaaataggt tataattacc gtctaagcaa tatttctgcc ggtatcggac gtggacaaat
    13021 ggaagtattg aatgatagag tagctaaacg aagagaaatt ttcaatcgat ataaggaagc
    13081 tttttctgga attgatagaa ttgaaatgat gccagaagtg gatggcatgg tgccaaatcg
    13141 ttggttgtct actttaacga tcaatgatta taattctatt gatcaagtag ttaacgtaat
    13201 aaataaacta aatgaaaaaa acattgaaac aagagctttg tggaaaccac tacatttgca
    13261 accagtattt caaggggtaa aaatgtatta ccatgataat aatcttagtg tgtcagaaaa
    13321 gttatttaat agcggcttat gcttaccttc tggaagtaat atgacagata gtgaacaaga
    13381 atttgttatt gatgagttta aaaaaatatt caagtaggtg tgatatttta tgaacatagg
    13441 aattattggt ttaggttcca tggggaaaag aagacttaga ctcattcaag aacactttaa
    13501 tgatatttta ctatgtggtg ttgatactaa tgaggcgaga cgaaaggaag ttgaaaagga
    13561 atttggaata ccaacttata atagtctaac agaggcaaaa aatttgtttg aaataaattc
    13621 agtttttgtt tgtacatccc ctataaccca tgaatttatt ataaaagagg ctttaaattt
    13681 agattgtaat atctttacgg aaatcaattt attaaatgaa tattatgatg aaataatcga
    13741 agtagctaaa aagaaagata gattacttta tctatcttct acatttttga agagaaaaga
    13801 aattcaatat attaagtcta aagtgacgca taataaaaaa atttcttatc aataccatgt
    13861 aggacagtat ttacccgact ggcatccttg ggaagattat cgcaattttt ttgtttcaaa
    13921 caaaaaaact aatgggtgta gagaaatatt cgctattgaa ttaccttgga ttatagatac
    13981 atttgggaaa gttaaatcgt ttactgtaat gacccagaaa ttatccaatc ttgatattga
    14041 ttattcggac agtttcactc ttattattga gcatgaaact ggtatagttg gaactttaag
    14101 tgtagatgtt gtttcaagag tagctaaaag aaatttaact ataattggtg aaaagatttt
    14161 aatagaatgg gaaggtaacc cggattctct attttcatgg aatgaagaaa cttctagtat
    14221 gacagatatt caattgtacg atgaggttat gcatgataat aattattcac atactattat
    14281 tgaagatgca tatttagagg agattaaaga atttttcacg cttttggaaa agaaaatgga
    14341 accccaatat acttttgaaa aagataagta tattattaac ttaattaacg acattgaggt
    14401 aaattaatga tgaaagtaat tttttttggg ttagggtcaa ttggaaagag acatctaaaa
    14461 aatctaataa gctatggaaa aaagaattct attaattttg atataacagc ttatagtagc
    14521 agtggaaaaa aagagtttga agaaataacg tatattcaaa atagagacga tttggataca
    14581 cattatgata tagcttttat tacaaatccg acttttaagc atctggaaac actaaatgta
    14641 attgttgaaa aagttgatta catattttta gaaaaacctg ctttttctga gagtattgat
    14701 cttactcaat ataattatga ttacaaaaat atttatgttg ctgctccact gaggtataaa
    14761 aatatcatgg aagttgttcg taatagtatt caaagtaaaa aagtatattc tgtaagagct
    14821 atttgttcta cttatcttcc tgattggaga aaaggtactg attatagaaa taattattct
    14881 gcctttaaat ctatgggggg aggagtagaa ttagactgta tacatgaatt ggattatatt
    14941 ataaacctat ttggtttccc taaatcagta aaaaaacagt ttggtaaata ttcgaatctt
    15001 gaaattaaca gtaatgattt agcaacatat atattgagat acgatgataa aattatagaa
    15061 attcatttag attattttgg aagagttcct acaagaaaat ttcaattgtt tactttagat
    15121 gaatgtatca atgttgactt attaaataat aaaataagtt ttgaagaaaa cattgttaaa
    15181 gaaatgcctg aatctgctaa tgatatgtat gagaaggagt tgaaatattt ctttgaaaac
    15241 gtagtaacag gcaaagaaaa ctggaatgat ttatatcatg caaacgaagt attgaaaata
    15301 gctgaggaga aataaatgga aattttattt actatttgtg gtagagctgg gtctaagggg
    15361 tttaaaaata aaaatttgaa atatttggca ggaaagcccc tagtccattt cgctttagca
    15421 atgatagata tctatcaaca aaaacatcct gaacataatt gcacgacttg tttgaatacg
    15481 gacagtaatg agttagtaga attgacgact aagttaaatc cgtctgtgaa aattgtagaa
    15541 cgtaaacctg aattagctac agatactgta gggaaaattg aagtgatacg tgattcattc
    15601 ttacaactag aaagagaaga taatatattt gatttaatta tagatttaga tttgacttca
    15661 cctttacgtg aagtttctaa tcttgaagaa ttaatagatg aacatctaaa aaatttagat
    15721 aaagacgtct acttttcagt tgtttctgca agacgtaatc cctattttaa tatggtaaaa
    15781 agaattgaaa atgaagttac tatagttaat aaatcaagat acacatctag gcaacagaca
    15841 cctgaagttt ttgaaatgaa tgcctcaatg tattctttta aacctgaatt tctaaaaaaa
    15901 agtaattata tttttgatgg gcaatgtggg ataataaaaa tgagagatta tctaatttta
    15961 gatattgata gtgaagaaga ttttaaatgg ttagaatttt tgtttcctaa atttttagaa
    16021 gattcttcgg agcttcaaga tatctataat tatttatatc ggaggtaaaa ggatgagctg
    16081 ttatcttatc accggtgggg ctggcttcat tggttctacc ttagccaatc atttaggaga
    16141 agaacatgtg gtaatcgtcg tcgatgactt atcaatggga aaagtagaaa atcttgatat
    16201 gacgaaaaat atcactttta ttgagggaga tgtcgctgag aaatccttga tggaagagat
    16261 catgaaagct aataaatttg attatatctt tcatttagca gcagttgcta gtgtggcaga
    16321 ttcagttgcc cgaccagtag aaacacatcg tgtgaatttt gaaagtgtat taatgatttt
    16381 agaattgatc cgcaagtatc aacctgattt aaaacggatc gtgtttagtt cttcagcggc
    16441 tgtttatggg gatgaaccga ctttaccaaa aaaagaagag tccgtgattc gcccattgac
    16501 gccttatgcg gttgataaat tcgctgcaga acaatatgtg ctagattatt gtcatttata
    16561 tgatgtaccc ggtagcgcag ttcgtttttt caatgtctat ggtccaaatc aaaatccgaa
    16621 ttctccatac agtggtgtga tttctattct cgtagatcgc tataagaaac aaatcgtagg
    16681 agaagcaact tcatttacat tatttggtga tggaagccag tctagagact ttgtttatat
    16741 agatgatgta atccaagcat tacttttagt tgcgaatgag gaagctgcac tggggaaaca
    16801 attcaatgtt ggaacgggta aagcaaccac acttttggaa ttgattcatg caatcaatga
    16861 aattctcggt gtagaattga cacttgaata caaagaagag cgttcgggtg atatccatga
    16921 ctctctagca gatattacta agatccagtc aattggctat caaccgaaat atggtatttt
    16981 aagtggaatg actaattatt tgaaaactga aatcaattaa aacatactaa gataagatta
    17041 gagggtaaat tcaggctctt tgtcaataag gactgatgag ttttgtaaaa tcaaatctgg
    17101 gataga
//
LOCUS       DARPZF010000051        17103 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.053, whole genome shotgun sequence.
ACCESSION   DARPZF010000051 DARPZF010000000
VERSION     DARPZF010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17103
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.053"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..153
                     /locus_tag="SLE65_002175"
     CDS             <1..153
                     /locus_tag="SLE65_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HEI8449447.1"
                     /translation="NKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFSFSVSTEIKV
                     LMGITA"
     gene            159..575
                     /locus_tag="SLE65_002176"
     CDS             159..575
                     /locus_tag="SLE65_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449448.1"
                     /translation="MEFREGAFDFQTSQQNRKFIPEDFQNLQLENMRLEDLFRLADDD
                     KYRFEVLKIKKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNR
                     NSTDVVMITDIYVEDEVIIKYMKPVIKLVNKNKGNG"
     gene            681..944
                     /locus_tag="SLE65_002177"
     CDS             681..944
                     /locus_tag="SLE65_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEI8449449.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDLKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            944..1216
                     /locus_tag="SLE65_002178"
     CDS             944..1216
                     /locus_tag="SLE65_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEI8449450.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTYEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            1293..1622
                     /locus_tag="SLE65_002179"
     CDS             1293..1622
                     /locus_tag="SLE65_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEI8449451.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            1612..1899
                     /locus_tag="SLE65_002180"
     CDS             1612..1899
                     /locus_tag="SLE65_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEI8449452.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            2185..3042
                     /locus_tag="SLE65_002181"
     CDS             2185..3042
                     /locus_tag="SLE65_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEI8449453.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            3043..3591
                     /locus_tag="SLE65_002182"
     CDS             3043..3591
                     /locus_tag="SLE65_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449454.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(3884..4831)
                     /locus_tag="SLE65_002183"
     CDS             complement(3884..4831)
                     /locus_tag="SLE65_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HEI8449455.1"
                     /translation="MHLEFSDYESLLVKICEDYYLEDINISEISKKYGITRYKALKYI
                     EDAREKQLVSISINSPYARNYELEEIFKNYFKTNIYILKSSEDLSQHDLLFSKFAADY
                     IQELIKKANVVALSWGDTVYKVIDQFKMGAREELIFTQFIGEIGKYNSLAGSTRLVQK
                     AAERYESSYLTLSIPLYVINETARELMALEPSLANTLATASHADMLISGIGTLSSIDS
                     VEPWNKHRKILFPSMTDTVGFLYGRPFNINGEFIKASEDKTFGLSLKEIFDIPKRIGI
                     CKSKFKAESCLGALNGNFFTDLFLDEKTAWKILSLIKKE"
     gene            5019..6206
                     /locus_tag="SLE65_002184"
     CDS             5019..6206
                     /locus_tag="SLE65_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HEI8449456.1"
                     /translation="MLDEVLEIHKKNVGVLRMETTEAVQDDQDLAKMYTPGVAELSLM
                     IEKNHALARELTISGKLVAVITDGSAVLGLGNVGNQAGLPIVEGKALLYKNLAGVNAI
                     PLAIEQKSVDEIVQTIVNLQNSFAGIHLEDIAAPKCFEIEEKLQEKLSIPVYHDDQEG
                     TAIVVLAGLINAAKIQRKTLTELRVLINGMGASGVATARLLIAAGIKNLTLVDKQGRL
                     KKQDSTLNKYQRELLDHIHDTNNNASVLEDAIVGQDVFIGLSIGNVLTPEMIGKMNDN
                     PIIFALANPVPEITPDLAKESGAKLIATGSSKYPNQVNNILVFPGLFKGLLLSKANKV
                     DLSLQLEVAKQLAAKVAEPTVEKFIPNVFDEGVANVVSQAVLDYLQKLKENEDNIHAE
                     NIK"
     gene            6187..7491
                     /locus_tag="SLE65_002185"
     CDS             6187..7491
                     /locus_tag="SLE65_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HEI8449457.1"
                     /translation="MLKTLNRIKIGFIPLSLYIILVLAYLAMTISNIVPENDMLVSLG
                     IMTVFAYLLEEIGKTIPILKDLGGKVLVVTFLPAFLVYKHWLPQSTVTVVSDFMNNNN
                     FLMFFITLLVVGSIASMNRQTLVKATSRIIIILILCDVIGSLIGTGVGILLGLSAWNA
                     YFFIVAPIMAGGVGEGAMPLSIGYAAILSGMGQNDIFGKILPCVMLGSLVAVLLSGML
                     KKIGEKYPQLNGQGNLIDGDDEHLENLKGSAKPVNIEKTLLAGVVAITIYFVAVYVEH
                     LLKSLLGFSIPSPVILLVSLMGAKMLGFIPKNIEEGGNSLYGFTVRGITPPLLFGVGV
                     AKTDWLELIEVFKNPATIVTIIVTVVAIVATAFIAAKFLKMYPVDTAIAVSCCSGQGG
                     TGALAILAAGDRMELMPFAQVAVRLGGAMTVTFAIFLMGLLS"
     gene            7517..8530
                     /gene="citC"
                     /locus_tag="SLE65_002186"
     CDS             7517..8530
                     /gene="citC"
                     /locus_tag="SLE65_002186"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEI8449458.1"
                     /translation="MFDQTDIQRLFLKNNYIKDQWENLLLDSGIQKKQIEDFQHLDQT
                     LGIYHKEKLVGTVSYQNNVIKYIAVSEKYKDGGHTFNVLVSAIIQAMSQQEIFHYIVF
                     TKPRYQKSFNFLGFETIVSTPKIAVLEMGDSSIKQYLERIPKVNGEKKAAIVMNANPF
                     TEGHYYLVKQAANNNDWVYVFVLEKEQNLFSTKDRLKLVQQGLQKLKNVIVLSGGEYI
                     ISPATFPTYFLREDDEIAKEQMVVDATLFKERIATYLDISARYVGEEPLSPMTRSYND
                     ILETILPPEIKVHVLARKKTEQHQVISASQVRKAYLAGQLEKIKYMVPETTYQYLKNK
                     RER"
     gene            8534..8827
                     /gene="citD"
                     /locus_tag="SLE65_002187"
     CDS             8534..8827
                     /gene="citD"
                     /locus_tag="SLE65_002187"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEI8449459.1"
                     /translation="MEINKSAIAGTLESSDVQIMISPNTEGIEIDLDSQVIEQFGKQI
                     KKVIYDTLAVYQIKNVKLKVVDKGALDCVIVARLKTAIHRSLGIQHQETPWEV"
     gene            8832..9737
                     /gene="citE"
                     /locus_tag="SLE65_002188"
     CDS             8832..9737
                     /gene="citE"
                     /locus_tag="SLE65_002188"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEI8449460.1"
                     /translation="MMKERLRRTMMFVPGNNPAMIKDAGIYGADSIMFDLEDAVSMAE
                     KDSARMLVAEALKTVDYGDTELIVRINDLHSEFGRADIFAMVKAGAHVLRLPKTETSE
                     DITEVEKVIIEAENYHNVPIGRTLMMAAIEGASGVLNAPAIAKASDRLIGIAIGAEDY
                     VTNMKTKRYPDGNELFFARSMIVHAARAAGISAFDTVYSDVDDMEGFLNEVRLIHQLG
                     FDGKSCINPRQIPVVNTVYQPSIKEIKRSLDIISAIEEAKEKGSGVISLNGKMIDKPI
                     VERAQRTLMLAKASRLIDEEGNIHA"
     gene            9730..11289
                     /gene="citF"
                     /locus_tag="SLE65_002189"
     CDS             9730..11289
                     /gene="citF"
                     /locus_tag="SLE65_002189"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEI8449461.1"
                     /translation="MHNKQRRSIPSSVLTKYKKEFQSVSLSPQTIQRCAPKVTTVTNQ
                     TNKLMHSIKEAIEKSGLKDGMTISFHHHLREGDFVFNQVMAVIREMGIKELTLAPSSL
                     TNTMNEMVIECIKDGTVTHITSSGMRGSLGEFISHGGMDNPVILRSHGNRPRAIESGE
                     LKIDVAFLGVPTSDDYGNANATVGKSVFGSLGYAKVDAQYADKVILLTDHLVPYPNTP
                     ISIPQTQVDYVVEVEAIGDPNKIGAGATRFTKNPKELKIAEMVKDVIVHSPYFKDGFS
                     FQTGTGGAALAVTRYLASEMEEKQIKASFALGGITKPTVDLLEKGLVEKVLDVQDFDK
                     GAAEGMARLENQQEIDASFYADPSNKGAVVNQLDVAILSALEIDTNFNVNVMTGSDGV
                     LRGAIGGHQDAATAKLTIISAPLVRGRIPTVVNDVTTLITPGKSIDVLVTEVGVAINP
                     QRKDLIAIFERIPQIPVFTIEELQQKAEKIVGIPEPLQFTDRIVAYVEYRDGSILDVV
                     RQVKEFEEERS"
     gene            11286..11843
                     /gene="citX"
                     /locus_tag="SLE65_002190"
     CDS             11286..11843
                     /gene="citX"
                     /locus_tag="SLE65_002190"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEI8449462.1"
                     /translation="MMFDTGEIQEIEDILIHKEQRANLQSNLLSKYSNSSLMVFTLNI
                     PGPIKNNPMIEQVFRQGQQSIQQMFLKKKVEMTYTKEINLPSGLDWYVIVTEAPLNLK
                     KWLVTLEEQDALGRLFDLDVLFKKGEQITIVSRQALNHGERPCFICGKSAKVCARNRT
                     HTVKEMQKKIEQIVADSLKGALKHA"
     gene            11836..12699
                     /gene="citG"
                     /locus_tag="SLE65_002191"
     CDS             11836..12699
                     /gene="citG"
                     /locus_tag="SLE65_002191"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEI8449463.1"
                     /translation="MHDNIQKIAQEAQLAMLYEVTCINKPGLVDPVDPGSHQDMDIFT
                     FLQSSVVLTPYFEEFIQTGLDRQHQPIEETFMAIRQIGLEAETAMFSVTNGINTHKGA
                     IFSLGIFLAICGRLTIWKVPCKKSFFQKEIQKMTKNLLNDFGKIDQTKPKAWTWGEYL
                     FVNHGLTGIRGEAKRGYPCVFDRGLPYYQAYQGSQQDKMIDTLLFLSMEVEDTNLIKR
                     SNNRHVFEEYQLLIRPYFELGGVKTIQGKKYLDYLNQQFKKKNWSIGGSADLLILTIF
                     LDKIMDKGWLC"
     gene            12933..13342
                     /gene="tnpA"
                     /locus_tag="SLE65_002192"
                     /pseudo
     CDS             12933..13342
                     /gene="tnpA"
                     /locus_tag="SLE65_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(13979..15151)
                     /locus_tag="SLE65_002193"
     CDS             complement(13979..15151)
                     /locus_tag="SLE65_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEI8449464.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRIGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LIASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWITFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNASWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNCVSANRLIGAVLIDQHDEWLSSSRKYIKFAK"
     gene            15825..16637
                     /locus_tag="SLE65_002194"
     CDS             15825..16637
                     /locus_tag="SLE65_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449465.1"
                     /translation="MILLAVSMSLLIYTHILSTFMSVIVIGFLFIGSLFSKRKERKEM
                     SNLISNMIKAVGWTILLTAYVWYPMLQQVLHQKINRPFRTKLQERALNISDSLIGAVN
                     NDLVTFTMGTIGVVSFILPLFFKKKFANKEKIINFCAVTTWFLSTNLFPWEFLQKTPI
                     QIIQFPWRILGFQVLFGSLILIIVFLKWKTSNKKSMCSLVGIVLLIFTVTVATEANYS
                     QKIQSYKGRLIMTKKDVTLYTTSRTGGLYDYAPLDALKYKDHLKKHEVKVYD"
BASE COUNT         5994 a         2562 c         3294 g         5253 t
ORIGIN      
        1 aataaatttt atcaaagtct ccgtacagcc tcttccacga ttaagggcat ggagaccatt
       61 cgaggaatat ataaaaagaa ccgaagaaat ggaacgctct tcagcttttc ggtgtctact
      121 gaaatcaagg tattaatggg aataacagcc taagatattt ggagttcaga gagggcgcgt
      181 ttgattttca aacttcgcaa cagaaccgaa aatttatacc ggaagatttt caaaacttac
      241 agttagaaaa catgcgttta gaagatttat ttagattagc agatgatgat aagtatagat
      301 ttgaagtttt gaaaattaaa aagaatgaac tattgaataa gttatatcct gagaatgcga
      361 taaaagcaca ttttggtgat gctaatcata tgtatagttg gttcattcct aaaagattta
      421 gagggaaaat caatgctgga gatcaagtga aagtactcaa tcgaaatagt acagatgtcg
      481 taatgataac agatatctac gtagaagatg aagttataat caaatatatg aagcctgtga
      541 taaaacttgt taataaaaat aaaggaaacg gataacactt tacaatgctg ttttggtact
      601 ccaatttaaa caaaacaatc gaatttacgt acttaattaa gtacgttaga atggagatat
      661 aaattagagg gggagtagat atggcaaaaa cagtcttaaa tcctagctca gcacggaaaa
      721 atttttataa gttgttgaaa gatgtaaatg agaatcatac ggaaattgaa atcattagtg
      781 agcgcagtga aaataatgcg gtgcttattg gtttggatga tttgaaagca atcaaagaaa
      841 cgctattact tgagcaaata ggcactttgg gtgttgttcg taagcgagaa aaagatgata
      901 gtggatttac taatgttgat gaaattgatt gggataactt ataatgaata actattctgt
      961 gatgattaaa aactcggcta aagctgattt aaagaaaatc aaacagtcta atttgaaacc
     1021 tcaatttgag aaggttattc agactttaaa ggaagatccc tatctcccta cccaatcatt
     1081 tgagaagtta aaacctacat atgaaggtag gtattctaga agattgaata gacaacaccg
     1141 ggttgtttat aaggtagatg aagatgaaca cgtggttgaa atttattcag caaggacgca
     1201 ttacgagtca cagtaattac ttgtaaatac attatctcgt ggtataatgt atttactaag
     1261 taattacata ctgttagaaa tgagggattt aaatgattac aaaaacaaga aaacaaggca
     1321 attcaatcat gttgacagta cctaaagatt ttaatgttcc taatggagtc gaagttgaag
     1381 caaagttggt agagaatggt attctttatg aatttgttga accacaaaaa gaattttatg
     1441 attttagcga agatattttg tctgatataa ttgcagaagg ctacgataaa gatgagattc
     1501 ttgtagaatt taagaataga aaaaacaaaa tgcattcttc ctttagagat attgctgaag
     1561 atacacttac taattctaaa gtaatgacta aagaggagtt ggcaacagaa attggcttat
     1621 gaaatcgttc cttcaaaaca tgtcattaag tatttaaaaa agctaaaaga gaagccattg
     1681 aaagaaaaat ttttgaattt aatttatgat gaaattgcga ttgatccata taagggtgaa
     1741 caaaaaactg gggatttatc aggtatttgg tctagtgggt tcaaatatgc gggcacaaca
     1801 tatagagtag cttacgagat tatagaaaac aaggttattc cagtattgtt atgtggaacg
     1861 catgaaaact tttatgaaca gttgaaaaaa ttaatctagt gatttgttgt cgttcttaag
     1921 aaggacggct tcttttttat cgaaaatctg attcgtctac atgactaaag tcgcgagtat
     1981 tctctgcttc tcgataaatt aaataacgtc attactttga ggaaagctat aaatcaatat
     2041 atttcaactt ttccttattt atgtactacc ttttacttat taattataag gtagtacata
     2101 tatatctttt ttttggtagt aactaaaaat aaatatgtta taatagtatc aaatgaatat
     2161 tgctaaaaga aaagaggtag gaacgtggta gcgaagaaat atgtaattgg taattttaaa
     2221 ggtggcgtag gtaaaagtac gtgcgcgcaa atgttagggt ttgaatcagc agttaatgaa
     2281 ggaaaaagaa ccttgataat tgacttggat atgcaaggaa atacttctga tgtgatgaac
     2341 ttaacgcata tgaacttcac taacgaagaa ggaggcggag aaggtgaacc gattgtttac
     2401 gaaaatactg tgactgacgt gttgataaac aatcttccac ctaaagaggc tgtctataaa
     2461 gtaatcaata acctctatat acttccagca gatatgtcct ttgaaatgta tgatgattgg
     2521 atcaaagacc aatataatga ttcattatcc caattcaaat atatgaaaga aaagctagaa
     2581 ccattatttg atgagtttga cgtcatctat ttagatgtcc caccttctat ttctgtatat
     2641 agtaaatccg cgatgtacat tgcggactgg gcaatcgtcg tcttacagac ccaagtaaaa
     2701 tcgatgagaa atgcgatgca atatcttgag tatatggact tttttgtgaa agaatttgat
     2761 acaaatttat atgttgctgg tgttattcct ttcatgttgg aaagcggtga cgcagtagat
     2821 caggaaatgt ataaacaagc ccaagagatt tatggggaac atttgattaa aaatgttgta
     2881 ctcaaaaatg cgcgcttaaa acgatacgac ggatcaggta ttacgatgga gaagacaaag
     2941 aaaggtctct taaaacaatg ggatcgcaaa agccacgaat tatttatcag tattttgaaa
     3001 gaattggaag aacacgagaa ttggtatgcg gaggtggagt aattggctga catcaaagga
     3061 cttgatattt ttgggaacaa caaaggactc gccaaaataa aaaaagaagc agaagcaaag
     3121 aaaaagcagc aagcaattac accatctgaa aataagcaat tagaagtgca ccaagttcaa
     3181 gaaataaaaa cttcctccaa tgttgaaaga cagagtagag gaagaacaaa aaaagttggc
     3241 gcaccaatca gaaagtttga taaggtttat tccaccaagc atcctttaaa actgtcgact
     3301 ttgttaaatg cgacttccag agttttagta gaaaagtatg agactaatat gacaagagat
     3361 gaattgctta gaaaagcttt agatgagtat attaaacaga atcttacgca agaagataag
     3421 caagatttgt ttaatgacgt ggtgaaagaa ctagacttgt tcagagaaaa atatccaatt
     3481 gttccagaat tagatgaccg tggagaaata ataagaacta ccagtcagat aaaacaagat
     3541 accgaagact cactgcgcaa agggtgggga atgaataata aagttagata gaaccccctt
     3601 tttatagcat aaaaaagatt tagaaggata tatgatctgc atgagaagta caataaaatt
     3661 aataagaagt aacattaacg aaaaaacgtg gaaattattc agtgaataca aagaaattaa
     3721 atcttgaaaa gtaatggagt atggcttgga aaagttcaaa aaatatcaag acaagcttct
     3781 caaaaaaagg gattttgata tccaataaaa agagtgaatc attgtactgc cctccaaaaa
     3841 agtagtacca aaaatctaaa ttttttggag gattttacat gactcactct ttttttatca
     3901 aagaaagtat tttccaagca gttttttcat ccaaaaataa atctgtaaaa aaattaccat
     3961 tcaaggcgcc taaacaactc tccgctttga acttactttt acaaatacca attcgttttg
     4021 gaatatcgaa aatttctttt aaagaaagac caaaagtctt atcctcagat gctttgatga
     4081 attcaccatt gatattgaag ggtcttccgt aaagaaatcc aacagtatcc gtcatgcttg
     4141 gaaataggat tttacgatgc ttgttccagg gttcgacaga atcaatagag gataaggtgc
     4201 caattccaga aattaacata tctgcatgcg aagcggttgc taaggtatta gctaaagaag
     4261 gttctagagc cattagttca cgtgcagttt cattgatgac atataaagga atactgagag
     4321 tcaaataaga agactcataa cgttcagcag ctttttgaac taatcgtgtg gagccagcta
     4381 aggaattata ttttccgatt tcgccaatga attgagtaaa aattaattct tcacgagcac
     4441 ccattttaaa ctgatcaatc actttgtaaa cggtatctcc ccaagatagt gcaaccacat
     4501 tggctttctt aattaattct tgaatgtaat cggcagcaaa ttttgaaaat aataaatcgt
     4561 gttgtgataa gtcttcacta ctttttaata tatagatatt cgttttaaag taatttttga
     4621 agatttcttc tagctcataa ttcctagcat acggagaatt aattgaaata ctaactaatt
     4681 gtttttcacg tgcatcttca atatatttta aagctttata tctggtgatc ccatattttt
     4741 tagaaatttc actaatattg atatcctcga gataatagtc ttcacaaatt tttacaagga
     4801 gtgattcata gtcagagaat tccagatgca tagtatagct cctaactttt tcaaatagat
     4861 attttttctc attataccaa aaaaattgaa tttagtcttt ttttaaattt ttaaaaataa
     4921 gcatcatttt tttaaaattt aaaatgaaag ggttttttta ttttaaaaaa agtgttaaag
     4981 tggttttgta attaaaaaat gtaaaaagga gtgaaggtat gcttgatgaa gttttagaaa
     5041 tccataaaaa aaatgtaggt gttttacgga tggaaacaac agaagccgtg caagatgatc
     5101 aagatttagc aaaaatgtac accccaggtg tagcagaact aagtttaatg attgagaaaa
     5161 atcatgcttt ggcaagagaa ttaacaatta gtggtaaatt agtggccgtt attacagacg
     5221 ggtcggcggt attaggtctt ggaaatgtag gaaaccaagc tggattacca atcgtcgaag
     5281 ggaaagcgct gctttataaa aatttagcag gtgtcaatgc gattccatta gccatcgaac
     5341 aaaaatcagt agacgagatt gtacaaacaa ttgtcaattt gcaaaatagt tttgcaggga
     5401 tccatttaga agatattgca gcaccgaagt gttttgagat tgaagaaaaa ttacaagaaa
     5461 aactttctat tcctgtgtat catgacgatc aagaaggaac agcgatagtt gttttagctg
     5521 gattgatcaa tgctgctaag atccaaagga aaacattaac tgaacttcga gttttgatca
     5581 acggcatggg agcatctggg gttgcaacag ctagactatt aatcgctgct ggtatcaaaa
     5641 atctaacatt ggtggataaa caagggagat taaagaagca agatagtaca ttaaataaat
     5701 atcaaagaga gttgttggat catatacatg atacaaataa taatgcaagc gttttggaag
     5761 atgcaatcgt tggacaagat gtttttatcg gtctttcaat aggaaatgtt ttaacgcctg
     5821 aaatgattgg aaaaatgaat gataatccga ttatttttgc tttagccaat ccagtaccag
     5881 agatcacacc cgatttagca aaagaatctg gtgcaaagct aatcgctaca ggttcttcga
     5941 aatatcctaa ccaagtaaac aatattttag tatttcccgg attgttcaag ggactattac
     6001 tatcgaaagc gaataaagtc gatctttcat tacaacttga agtagccaaa caattagctg
     6061 ctaaggtcgc agagcctacg gtagaaaaat tcatccctaa tgtttttgat gaaggagtcg
     6121 caaacgtcgt ttcacaggca gttttggatt atttacaaaa actaaaagaa aacgaggata
     6181 atatacatgc tgaaaacatt aaatagaatt aaaattggtt ttattccttt atctctttat
     6241 atcattttgg tactcgcgta tcttgcaatg acgataagca atatcgttcc agaaaatgat
     6301 atgttagttt ctttgggtat tatgactgtt tttgcttatt tattagaaga aattggtaaa
     6361 actattccta ttttaaaaga tttaggtggt aaagtattag ttgttacatt tttgcctgca
     6421 tttctagtct ataaacattg gctacctcaa agtactgtaa ctgtggtttc tgattttatg
     6481 aataataaca atttcttgat gttctttatc acactactag ttgtcggcag tattgcttca
     6541 atgaatcggc aaacattggt taaagcaact tcacgtatta tcattatttt aattttatgc
     6601 gatgtgattg gttctttgat aggaacaggt gtgggaatac tccttgggct atctgcttgg
     6661 aatgcgtatt tctttatcgt tgcgccgatt atggctggtg gtgttgggga aggagcgatg
     6721 ccattatcga ttggttatgc agcaatatta tctggtatgg gacaaaatga tatctttggg
     6781 aagattctac cgtgtgtgat gttgggaagt ttagtcgcag ttctactgtc tggtatgctc
     6841 aaaaaaattg gagagaaata cccacaatta aatggtcagg gtaatttgat cgatggggat
     6901 gatgaacatt tagagaactt gaagggttca gctaaaccag tcaatattga aaaaacattg
     6961 ttagcaggcg tggtagcaat aacgatttat tttgttgctg tctatgttga gcacttatta
     7021 aaatcactcc ttggcttttc tattccttca cctgtgatct tattagtctc tcttatgggg
     7081 gctaaaatgc ttggttttat ccctaaaaat atcgaagaag gtggaaattc gttgtatgga
     7141 ttcactgttc gtgggatcac acctccctta ctttttggcg taggggttgc aaaaacagat
     7201 tggttagagc tgatcgaagt atttaaaaat cctgcaacga tagtaacaat cattgtgacg
     7261 gtagtagcta ttgtcgctac agcttttatc gccgcaaaat ttttaaaaat gtacccagtt
     7321 gatactgcca tcgcagtttc atgttgtagc ggacaaggcg gtacaggtgc tttagctatc
     7381 ttagctgcgg gtgatcgcat ggaattaatg ccatttgcac aagttgctgt tcgactaggg
     7441 ggtgctatga ccgtaacgtt cgctatcttt ttaatgggtc tgctatcata agaacataaa
     7501 gaaaggacgt gaccatgtgt ttgatcaaac agatatccaa cgattatttt taaaaaataa
     7561 ctatatcaaa gaccaatggg aaaatctttt gcttgattca ggaatacaaa agaagcaaat
     7621 cgaagatttt caacatttag atcaaacatt gggtatatac cataaagaaa agttagtagg
     7681 aacagtatct tatcaaaaca acgtgattaa atatatcgcc gtgtctgaaa aatataaaga
     7741 tggtggacat acatttaatg tactagtctc tgcaataatt caggcaatga gtcaacaaga
     7801 gatttttcat tatattgttt tcacgaaacc gcgctatcaa aaaagtttta actttttagg
     7861 ttttgaaaca atcgtatcta ccccaaaaat agctgtatta gaaatgggag atagttctat
     7921 aaaacagtac ctagagagga ttcctaaagt gaatggtgaa aaaaaagcag caattgtcat
     7981 gaatgcgaac ccatttacag aagggcatta ttatttagta aaacaagctg ccaataacaa
     8041 cgattgggta tatgtatttg tactcgaaaa agaacaaaat cttttttcga cgaaggaccg
     8101 actcaaatta gttcaacaag gattacaaaa actgaaaaat gtcattgttc tatcaggtgg
     8161 cgagtatatt attagccctg caacgtttcc cacctatttt ttacgagaag atgatgaaat
     8221 agcaaaggag caaatggtcg tagatgctac tttattcaaa gaaagaattg ccacttattt
     8281 agatatctct gctagatatg tgggagaaga accactttcc ccaatgactc gttcatataa
     8341 cgacatactg gaaacgattt taccccctga aataaaagtt catgtccttg caaggaagaa
     8401 aacggaacaa caccaagtta tttctgcttc tcaagttcgt aaagcgtatc ttgctgggca
     8461 attggaaaaa ataaaatata tggttccaga aacaacctat caatacttaa aaaataaaag
     8521 ggagcgttaa gtaatggaaa taaataaatc agcgattgct ggaacattag agtcaagtga
     8581 tgtccaaatc atgatttcac cgaatacaga aggaatagaa atcgatttag acagtcaagt
     8641 gattgagcaa tttggaaaac aaatcaaaaa agttatctat gacacactag cagtttatca
     8701 gattaaaaac gtaaaactca aggtagtaga taaaggggca ttagattgcg ttattgttgc
     8761 acgattaaaa acagcgatcc atcgttcctt aggtatccaa caccaagaaa caccgtggga
     8821 ggtttaatta gatgatgaaa gaacgtttga gaagaacaat gatgtttgtt ccaggaaata
     8881 atccagcgat gatcaaagat gcaggtattt atggtgctga ctcgattatg ttcgacctgg
     8941 aagatgcagt gtctatggca gaaaaagaca gcgcaagaat gcttgtggct gaggcattga
     9001 aaacagtgga ttatggtgac acagaattaa ttgttcgaat aaatgacctg cactcagaat
     9061 ttggacgtgc agacattttt gcaatggtta aagccggcgc gcatgtatta cgtttaccta
     9121 aaacagaaac ctctgaagat ataacagaag tagaaaaagt gattatagaa gcagaaaact
     9181 atcataatgt tccgataggg cgaacattga tgatggcagc cattgaaggt gcttctggtg
     9241 tattgaacgc acctgcgatc gccaaagcat ctgatcgatt gattggaatc gccattgggg
     9301 cagaagacta tgtgacaaat atgaaaacca aacgatatcc agatggaaac gaattgtttt
     9361 ttgctcgcag tatgatcgtt catgctgcac gtgcagcagg catttccgca tttgacactg
     9421 tttactctga tgtggatgat atggaaggat ttttaaacga agtacgttta atccatcaat
     9481 taggttttga tggaaaatct tgtatcaatc cacggcaaat tccagtagtc aatactgttt
     9541 atcagccgtc aatcaaagaa atcaaacgat cactagacat catctcggca atcgaagaag
     9601 caaaagaaaa aggttctggc gtaatttctt taaatggaaa aatgatcgat aaaccaattg
     9661 tagaacgtgc acaacggaca ttgatgttag caaaagcatc acgattgatt gatgaggagg
     9721 gaaatatcca tgcataataa acaaagacgt agcattccat caagtgtttt aacaaagtat
     9781 aaaaaagaat tccaaagtgt ttcattatcg ccacaaacga ttcaacgttg tgcaccaaaa
     9841 gtaacgactg taactaatca gacaaataaa ttgatgcact cgatcaaaga agctatagaa
     9901 aaatcgggct taaaagatgg aatgacgatt tcatttcatc atcatttgag agaaggtgat
     9961 tttgttttta accaagtgat ggccgtgatc cgtgaaatgg gcatcaaaga attgacctta
    10021 gcaccaagtt ctttaacgaa cactatgaat gagatggtta ttgaatgcat caaggacggt
    10081 acagtaactc atatcacaag cagtgggatg cgcggcagct taggtgaatt tatttctcat
    10141 ggaggaatgg acaatcctgt gattttacgt tctcatggta atcgtccacg tgcaattgaa
    10201 agtggtgaat tgaaaatcga tgttgcattt ctaggagtac caacatctga tgattatgga
    10261 aatgctaatg cgactgttgg aaaatccgtt tttggttcat tagggtatgc aaaagtagat
    10321 gcacaatatg cagataaagt cattcttcta actgatcatt tagttcctta ccctaatacg
    10381 cccattagta ttccgcaaac acaagtcgac tatgtcgtgg aagtagaagc aattggtgat
    10441 ccgaataaaa tcggtgctgg tgctacacgg tttactaaaa acccaaaaga attaaaaatt
    10501 gctgaaatgg tcaaagatgt cattgttcac tcaccttatt tcaaagatgg cttttctttt
    10561 caaacaggaa cgggtggtgc agctttagca gtaacgcgtt acttagctag tgaaatggaa
    10621 gaaaaacaga tcaaagcttc ttttgcatta ggtggcatca ctaaaccaac ggttgattta
    10681 ttggaaaaag gtcttgttga aaaagtgtta gatgtccaag actttgacaa aggagcagct
    10741 gaaggaatgg cgcggcttga gaaccaacag gagatcgatg cttcctttta tgctgatcca
    10801 agtaataaag gagcggttgt taaccaatta gatgtcgcta ttttatctgc attagaaatt
    10861 gacacaaact tcaatgtaaa tgttatgact ggttcagatg gtgtgctaag aggtgcgatt
    10921 ggtggacatc aagatgcagc aacggctaaa cttactatca tctcagcgcc gttagtacgt
    10981 ggccgaatac ctacagtagt aaatgatgtt actacattga tcacaccagg gaaaagtatc
    11041 gatgtattag tcacagaagt aggggttgct atcaatcccc aacgtaaaga tctaatagct
    11101 atttttgaaa gaattccaca aattcctgtt tttacaatag aagaattaca gcaaaaagca
    11161 gaaaaaatag taggcatccc ggaacctttg caattcacag atcggatagt tgcctatgta
    11221 gaataccgag atggttcaat tttagatgtc gttcgtcagg tgaaagaatt tgaagaagag
    11281 agatcatgat gtttgatact ggagaaattc aagaaatcga ggatattttg atccataaag
    11341 aacaacgtgc taacttgcaa agcaacctgc tttccaagta ttcaaatagt tcattgatgg
    11401 tctttacatt gaatattcct gggccgatca aaaataatcc aatgattgag caggtatttc
    11461 gtcagggaca gcagtcaatt cagcaaatgt ttttaaaaaa aaaggtggaa atgacgtaca
    11521 caaaagaaat caatttgcca agtggattgg actggtacgt aatagtaaca gaagcacctt
    11581 tgaatctcaa aaaatggttg gtcacgttag aagagcaaga cgcattaggt agactttttg
    11641 atttagatgt cttgttcaaa aaaggagagc agataacaat tgtcagtcgc caagctctta
    11701 atcatgggga acgtccttgt tttatttgtg ggaaatcagc aaaggtatgt gcacgtaatc
    11761 gtacacatac tgtgaaagaa atgcaaaaga aaatcgaaca aatagtagcc gattccttaa
    11821 aaggagcatt gaaacatgca tgataatatt caaaaaatag cacaagaagc acaattagcg
    11881 atgctttatg aagttacatg tatcaataaa ccaggattgg ttgatccagt agaccccggg
    11941 tctcatcaag atatggacat ttttactttt ctacaaagta gtgtagtttt gactccctat
    12001 tttgaagaat ttatccaaac aggattggac cgacaacatc aaccaattga agaaaccttt
    12061 atggcgattc gacagattgg tttagaggct gaaactgcga tgttctcagt gacaaatggt
    12121 ataaatacac ataaaggtgc tatcttttca ttggggattt ttcttgctat ttgtggccgg
    12181 ttaactattt ggaaagttcc ttgtaaaaaa agtttctttc aaaaagaaat tcaaaaaatg
    12241 acgaaaaatc tacttaacga ttttgggaag attgatcaaa caaaaccaaa agcatggact
    12301 tggggagaat atctatttgt taaccatgga ttgacaggga tacgagggga agccaaaaga
    12361 ggttatcctt gtgtttttga ccgaggattg ccttattatc aagcatatca agggtcgcaa
    12421 caagataaga tgatagacac tttacttttt ctatcaatgg aagtagaaga taccaatttg
    12481 atcaaacgaa gtaataatag acatgttttt gaagagtatc aattacttat tcgtccttat
    12541 tttgaattag ggggtgtaaa aaccatacaa ggtaaaaaat atttggatta cctaaatcag
    12601 caatttaaaa agaaaaattg gagtattggt ggaagtgcag acttattgat ccttacaatc
    12661 tttttagata aaatcatgga caaaggatgg ttatgttgat actataatac attattttgt
    12721 attagtaagc taataactaa aaaatggttc aatacaaata ttttataaaa aatggtagtg
    12781 cctatccttt cagattgtag acaaagaaaa atttctttgt ctacaatttt tttgttaatg
    12841 acttcagtca gtttcgtgcg caaagcgtgc gaaacaagaa aaccatgcgt ttctacacgt
    12901 ggaagaacta gcatatcgaa aggagttttt tcatgtcaaa tgacgataaa agtttagccc
    12961 atactcgttg gaattttaag tatcatattg tatttacacc aaaatatcga cgaaaagtaa
    13021 tctataggca attacgaaaa gatattggaa aaatacttag gaagttgtgc aaaataaaaa
    13081 acgtggaaat tatagaagca catgcaacgc cagatcatat tcacatgctt gttcaagtac
    13141 catcaaaaat aagtatatcc agttttatag ttatctgaaa gatcgtagtg ctgtgctaat
    13201 ccacgagcag cacgtaaatc acaaatatag atacggaaat aaatcatttt ggtcggagga
    13261 atattatgtg agtacagtcg aattgaatca aaagacaatt gaaaaataca tccgtgaaca
    13321 agaagctgat gatcgcattt gagatagtat aagtaaaaga gagtagatgt tgcaataaca
    13381 aaagggtaaa aatggactac ctccagtaaa ataccgaaaa atagtttaac ttttggagat
    13441 aagtccattt aagggtctat agaatgacaa tttttttagg ggattttact attattactt
    13501 caagacccgc ttggattcgc aaagtgagtg aactcttaaa actacctgat agtaggttgt
    13561 tttaagagtt atctgaaagt aaaaattgca tttatatttt tgataaatac gtaaatttat
    13621 atatacgtat ttatcaaagt tttaggccaa aggaatattg tgtaaataca ctaggattga
    13681 atgaatagac cagaagaaat tgcgtccaag aacaaaagaa gcatgatagt gctctatata
    13741 aattgggcat tcaagaatct gaaatttaaa ggtagaattt tagttagact tttagatttt
    13801 aaacacaaaa ataaccatac aagcaacaag aagcaaagtg ctatattata aattgtccgt
    13861 ccgtttactt acataagatc attggggcta tttttaaaag agaataatag ataataaatg
    13921 aaaaaaaagt caagtccaca atcctgtgta aaatactata caatgctctc actatttttt
    13981 acttggcaaa tttaatatat tttcttgatg aagaaagcca ctcatcgtgt tgatcaataa
    14041 ggactgctcc aattaaacga ttggctgaaa cgcagtttgg aaagatacga ataatttttt
    14101 ctcttctgcg cacttcttga ttcagtcgtt caattagatt ggtactcttt agtcgattgt
    14161 gggaatttcc ttgtacggta tattgaaagg cgtcttcgaa tccatcatcc aatgatgcgc
    14221 aagcttttga atattttggt tgatcgatat aatcatgaat caatcgattt ttagcctcac
    14281 gagctaagtt aatatctgtg aacttaaaaa ttcctttaac agcttctctg aaagattttg
    14341 aatttttttt aggaatggtg gtaaagatat ttcttaggaa gtgaacttgg catctttgcc
    14401 aacttgcgtt ggtgaaggat tttctaatgg cagagactaa tcctttgtgc gcatcagaaa
    14461 taacgagttc tgtaccttgt aaaccgcgtt cttttaggta ttcaaaaaat gttatccagg
    14521 tctcttcgct ttcgccactt tgaatcatga agccgataat ttcacggtcg ccatctttgg
    14581 ttattccaat cgctatatga cagctttttg agagtactcg attttcttct cgtactttta
    14641 tatagagtac atcggtcatt aagtaaggat aatttttttc tgataataaa cgattctgcc
    14701 actcgttaac cattggttct agctgttctg ttaagctaga aacgaaggac ttagagacgg
    14761 atttaccaca aagttcttcc acaatttttg atactttacg agttgaaacg cctgatacat
    14821 acatttccaa cattgaagca atgagggctt tttcgtttcg ttgataacgt tcaaacactg
    14881 tgggtgaaaa atggccatca cgtgttctgg gtacttttaa ttctagcgtg cctatacgtg
    14941 tcgtaaagct gcgctcataa tagccatttc gttgactttg tcggttttct gttcgttcat
    15001 attcttttgc ttgaatatat tctgttcgtt gattttccat tagttgatta aataccgttg
    15061 ttaaaatatt tttagaaacg tcatccttta cagaatattc aataatgctt tgaatctctt
    15121 cgcttttcag tgtaaaatgt acttgggtca tgtaaaagtc ctcctgggta tgtttttgtc
    15181 gttaaaaaca ttgtaccgta aaaggactgt tacatggcct ttttactttt acacaattat
    15241 aaggacttta tcgaaaaaaa gcagttattt gttaaaatca ttgatattat taataataag
    15301 tattttttga aaggggaaat ataaaaggtt tttgaaaata aataaaaaat agtattactt
    15361 gttctattgc tagttattgc tagtctttat tcttttttgt tttttaggga tgtacaaaag
    15421 atctcaacca caggagacat tgcttttcac ttttctagaa taaaatgctt gtcctcagta
    15481 ttttctggtc caataaattt taccacattt aatagctatg gcggaggcgt gaattttttt
    15541 atccatatct aacatctttc cagccgtaat attttactgg acaacaaaca atttgattct
    15601 aagttatata cttactatac gttgggatac tgaatatctg tacaattcta gtgagctatc
    15661 aatatggaca aaagaataga tgcagccttc ttattcagct gtttgtatag cttttatgga
    15721 ttgatatata ttagcgtact gcaatttcag aatcaattgc gttgacgatt gtaccagttg
    15781 tcttgtatta cacatatact cttctttatg aaagaaaaaa ctgcgtgatt cttttagctg
    15841 tcagtatgag tttgctcatc tatacccata ttctctccac ctttatgagt gtgattgtta
    15901 ttggcttctt gtttatcggc tctcttttct ctaagcggaa agagagaaaa gaaatgtcga
    15961 atctgatatc aaatatgata aaagctgttg gttggaccat tcttttaaca gcttacgttt
    16021 ggtatccgat gttacaacaa gtcctacatc aaaaaattaa tcgtcctttt cgcacaaaac
    16081 ttcaagaaag ggcattaaac atttctgata gtttaatcgg tgcagtaaat aatgatttag
    16141 ttacatttac aatgggaaca attggtgtgg tttcatttat tcttccactt ttctttaaaa
    16201 aaaaatttgc caataaagaa aagattatta atttttgtgc agtgaccact tggttcttat
    16261 caacgaatct ttttccatgg gaatttttac aaaaaacacc tattcaaatc attcagtttc
    16321 cttggagaat cttgggtttt caagtgcttt ttggttcatt gatcttaatt atagtgtttt
    16381 taaagtggaa aacaagcaac aaaaaaagta tgtgtagcct tgtaggaata gtccttctta
    16441 tttttacagt gactgtagca acagaagcga attattcgca gaaaattcaa tcgtataaag
    16501 gtcgtttaat tatgaccaaa aaagatgtta cactttatac aacctcgaga actggaggtc
    16561 tttatgacta tgcaccatta gatgcattga aatataaaga tcatttaaag aaacatgaag
    16621 taaaagtcta tgattgatgg gagaatgcat ctcataaagc acataattct aaaataatct
    16681 atacagtagg agatgcgaat gagcaaaata tcacgttacc tgtatttaat tactgggaac
    16741 agttatgaaa gtaaatggga aaaagagcac tatagaaaat gacaatggtt tagtgtctat
    16801 taaaggtacg ggaaaaagaa ctatagttga ggtttcatct acgtatccaa ctacgatgat
    16861 tctatcttta ttaattagtt caataacttt tatattctta tttacacgtt atttaataag
    16921 atgctgcggt taaatgaaaa tagattagat agatattata aatatgttga ttctattttc
    16981 atagcaatgg agaaaataca ttagcaatat ataaaagaag gtatcaagag tcacggtgaa
    17041 tttattccga aaagtgaaaa gaacaaatat aaaatttaat aaaaatatag aactaaatag
    17101 gaa
//
LOCUS       DARPZF010000052        16999 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.054, whole genome shotgun sequence.
ACCESSION   DARPZF010000052 DARPZF010000000
VERSION     DARPZF010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16999
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.054"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..125)
                     /locus_tag="SLE65_002195"
     CDS             complement(<1..125)
                     /locus_tag="SLE65_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HEI8449466.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(229..540)
                     /locus_tag="SLE65_002196"
     CDS             complement(229..540)
                     /locus_tag="SLE65_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEI8449467.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(542..739)
                     /locus_tag="SLE65_002197"
     CDS             complement(542..739)
                     /locus_tag="SLE65_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HEI8449468.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1133..2860)
                     /locus_tag="SLE65_002198"
     CDS             complement(1133..2860)
                     /locus_tag="SLE65_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEI8449469.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2853..4046)
                     /locus_tag="SLE65_002199"
     CDS             complement(2853..4046)
                     /locus_tag="SLE65_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEI8449470.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4233..4877)
                     /locus_tag="SLE65_002200"
     CDS             complement(4233..4877)
                     /locus_tag="SLE65_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8449471.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4971..5105)
                     /locus_tag="SLE65_002201"
     CDS             complement(4971..5105)
                     /locus_tag="SLE65_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HEI8449472.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5107..7239)
                     /gene="feoB"
                     /locus_tag="SLE65_002202"
     CDS             complement(5107..7239)
                     /gene="feoB"
                     /locus_tag="SLE65_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HEI8449473.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFFMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7236..7709)
                     /locus_tag="SLE65_002203"
     CDS             complement(7236..7709)
                     /locus_tag="SLE65_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HEI8449474.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8103..8327
                     /gene="nrdH"
                     /locus_tag="SLE65_002204"
     CDS             8103..8327
                     /gene="nrdH"
                     /locus_tag="SLE65_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEI8449475.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8486..10645
                     /gene="nrdE"
                     /locus_tag="SLE65_002205"
     CDS             8486..10645
                     /gene="nrdE"
                     /locus_tag="SLE65_002205"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEI8449476.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10695..11660
                     /gene="nrdF"
                     /locus_tag="SLE65_002206"
     CDS             10695..11660
                     /gene="nrdF"
                     /locus_tag="SLE65_002206"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEI8449477.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11749..12888)
                     /locus_tag="SLE65_002207"
     CDS             complement(11749..12888)
                     /locus_tag="SLE65_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEI8449478.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13197..13910)
                     /locus_tag="SLE65_002208"
     CDS             complement(13197..13910)
                     /locus_tag="SLE65_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEI8449479.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14164..14865)
                     /gene="nagB"
                     /locus_tag="SLE65_002209"
     CDS             complement(14164..14865)
                     /gene="nagB"
                     /locus_tag="SLE65_002209"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEI8449480.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15099..16631
                     /locus_tag="SLE65_002210"
     CDS             15099..16631
                     /locus_tag="SLE65_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEI8449481.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16822..>16999)
                     /locus_tag="SLE65_002211"
     CDS             complement(16822..>16999)
                     /locus_tag="SLE65_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8449482.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5276 a         3494 c         2909 g         5320 t
ORIGIN      
        1 gaaaaaacac attccactaa atttgatgcc ggttttcctt gaggttttgt tccagcacct
       61 cctttaattt ttttaagctc ttgatctgaa cattgtttag catttagtct atttttttct
      121 tccattacga ttccccctac aaactataaa tacttttatg tcactgattc aatataccta
      181 tttttctaat caaaaaattt tgagacatat ttaatattat aagtatcatt aaaattgaga
      241 tttatctcca taatctgctc gatataaacc atttattcca gcagttcttc caatttcact
      301 caaatttctt attaattcct cttgatattc agtgaatctt attttattag tataagcagt
      361 aaaatataga taattcacca atctatttat taaaggactg ggatctaatt catatttttg
      421 tttttctaat tttaaatata ccttttgtaa aacctcaaga atatcagaat atttaggatc
      481 tttacttata gatatatcat tatataattc atgaacaatt tgcttagcat tttttttcat
      541 tttagcactt ccctggaatt gctccaccta aaaaaccacc tatagacatt cctgcaatac
      601 aagtagttgc cttggcccaa tcgaccgtac atttattttt agtgcaatac actccatttc
      661 cataatattt tccactatga gtggtacccc catagataag ttgtgtctct ttaatagaca
      721 aaatttttaa atgtttcata atctaatcac ccctaaatta atgtttttag actattattc
      781 taacattcat taaatttcaa aaaacaattc cttcttgaaa cgtagcaaaa taattcctga
      841 ataagaattt aatcactttt aagtatataa actatgtata ttctttaata ttttttgaga
      901 atgcacttcg tacataataa actttaatca cattagtctt tcatacctac gatcgatctc
      961 tttgactcgc acccataaat tcataatagt ttgtcggcgt ctttgaacgt ttcgaagatg
     1021 agctacgcat tctctttttt tatagacaaa aaagatagag acgaacatgg agcttccaaa
     1081 tttggatatt tgatccaatt ttggaagctc catttatttc gtgtctgtct ttttattttt
     1141 tccagctttc gactaattct tggttctctt tgatccagtc ttttgctgct tgctgtggat
     1201 cttttccatt gttgatttcc aacataactt tttccatatc tttttctgac caatggaaat
     1261 tgtctaatac tttgtaagct tctggctggt cttctttcaa tccttttcga accatcgtat
     1321 ggatctgctc ttcgcttccc attccgtttt caggatcttc taagtatttc agatcatatt
     1381 tggcaaacat ccaatgaggt gtccatcctg taactacaat tggttcgtgt tttttgatcg
     1441 cttgacctag tgcaacggtc attgctcctg aagaagatgt ctctactttc cagtctttca
     1501 agttgtcata tttttggatc gtgttttcag cagccgtaac tacaccagct cctggctcga
     1561 ttcctatgat tttcttacct gcctgatcgg ttaactcatc gatcgaattt acatccatgt
     1621 aggctggcac tgctaaacca acttttgctc ctgtcaaatt ggcacctagg tcttcgactt
     1681 gatctttata ttgtgcatat tgtgaaccat gagttttagg tagccaagct gaaaccatgg
     1741 catctgactc gccatttgaa acagatttcc acatgattga attatctaat ggcgtcatcg
     1801 ttacatcata gcccatttgt ttcaatactt caccgactac atttgttgaa gcaacttctg
     1861 tatcccattc aacataagat aagttgatac gttttgtttc tttggcagat gaaaaactcc
     1921 ctataccaat cgcacctaag atcactacta ctacagcacc aatgatcagt ccttgacgtt
     1981 ttttactttt ctgtgttgtt gctcctgcag cttttttatt gtttggctgg ttcaaatgct
     2041 gtgtaaaacg gtcaatgatg attgctaaga taactaatgc aaccccgttg acaaatccat
     2101 tcccgacttg tgctctttgc aatgctgata atacgccgcg tcctaagccg ggtgcaccga
     2161 tcatagaggc aataacgacc attgaaagtg acagcattgt tgtttgattg atccctgcca
     2221 tgatcgtact tttagctaaa ggcaattcta gtttgaatag tttttgacga cttgtgctcc
     2281 cgaatgaatc agaagcttct actaattctt taggaacttg tcgaatccct aaattcgtaa
     2341 aacgaacggt tggtggcaga gcaaagatga ctgaggcaaa tacccctgga accatcccga
     2401 taccgaaaaa tgcaactgct ggaatcaaat aaacgaatcc tggcattgtc tgcataaagt
     2461 caaggatcgg tttgataata ctttgggctt tactgctttt tgccatcaag atccctaatg
     2521 gtaccccaat gatgatcgag atcacactag ataaaagaac aagtgtgaca gtattcatca
     2581 aatcattcca tagaccttgg ttataaataa accatagacc gattaatgtg aacaacgtaa
     2641 gtcctggacg tttcttagaa ataaagaaag ctgctaccgt caataacaag ataaacaaag
     2701 gagctggaat cactaacagt aaatttgtaa tccccgacat cactgcctgt ccaatcgttt
     2761 gtaaaaatga aaataggcca gaaaaagttg tcgtaaacca ttctgtgata ttttctaccc
     2821 agtttgccac tggtaattga tagttcaata gattattcat gttcactcac ctcgcttgtt
     2881 tctgctaatg cttcaatcac actacctcgg atgacgacac cttttaattt tccatcctct
     2941 acaactgcaa gtggagtcgg tgagtcataa ataatattga aaatatcact taccaccatg
     3001 tctttcccaa tcaccgtcac attttcatct aggaagtcga tcaatggacg tttttgcttc
     3061 ctagcttcta acgcttgatc tgcagtgatg atccctttca ggtgtctctt tctgtcaaca
     3121 gccatcagca tgctgacttc ttcattacgc atccttgtca atgcaacgtt tggtccatca
     3181 gattcgatat tcgtcgtcaa tgcaggtacc atgatgtttt gagccgtaag cactttggaa
     3241 cgatcgactt cttccacaaa ttcacgtaca taatcatttg ctggattggt caatatttct
     3301 tcacctgttc cgatctgcat gatttcgccg tctttcatca aggcgattct gtccccaatc
     3361 cgtaaagctt cattcaaatc atgggtaatg aaaataatcg ttttttgaac attggcttgc
     3421 aggtccagta attcgtcttg catttctcgc cggatcagcg gatcaagagc cgagaacgct
     3481 tcgtccatca gcaagatctc aggatcattt gctaaagctc tggctaggcc aacccgttgt
     3541 tgcatcccac cagataactg actaggatat tggtctttaa atgaaagcaa actagaattt
     3601 tctaatgctt tttctgcttt ttcttgtcgt tcttctttag gtacaccacg gacttctaac
     3661 ccgtattctg tattttccaa gatcgttcga tgtggaaaca gaccgaagtt ttggaaaacc
     3721 atattgattt tatgacgacg gacttctcgc aattcttctt tgcttaactt cgatacatct
     3781 tctccatcaa tatagatact gcccgaagtt ggctcaatca gacgattcaa tagacggatc
     3841 aatgtggatt tcccactccc ggaaagcccc atgatcacga agatttctcc ttcttttacg
     3901 tcaaaattca cgtcatacac accaaccgtt gcaccggttt tctttaaaat ctccgttttc
     3961 ggctggtgat cattcatcat atctaaagcg gcttgtgtct ttttaccaaa tatctttgtt
     4021 aaatgtttta cttctacttt taccaaacaa attctccttt tttatgtaaa ttcatttttc
     4081 tttctgaaaa aagtgaccac actatgttaa catcatgtag tcactttgtc aaaaatgaaa
     4141 gaaatttgct tgtccaaact gaaaaaaact tggctaaatc tttgtaaata aaaggtttag
     4201 ccaagttaat atttttttaa tatttcacac aatcattctg caagctgatg ctccgggtaa
     4261 aaaaagtttg tcatacgctg tagtgtatat tcatttccaa taaaatgaac gatgtcccct
     4321 gccgtaaatt tagcataggg gccaggtgaa acaagcagtt cttcattatg agaaattgcg
     4381 ataactgtgg cgccagtcgc ctgccagata ttcaactcgc taattgaacg gtccagatgc
     4441 attgcttttt ctgataaaga taattcaaac ggaagtaaag gattcatctt atgtattcgc
     4501 ttcgtttgat tgaccagctg atccaataat tgagaaaaat gattcagctc atcttgttgc
     4561 ttctccacac ttgccatgat ttctgctttt gtatcttgga tggattgtac atcttgatat
     4621 tgcaatagga aatcttttgc tttttccttc gaagcaacaa atgccccact tccatgccgt
     4681 acttccatga ttccaagatc taccagcaca ttgatagcct tgcgggtagt ctcaggagaa
     4741 gcattgtacg tactggcaag tgttgagcgg gcatggatct tctcacccac tttatatcgg
     4801 ttttcaacga tacgttcggc taaatcaaca gcaatctgct ggtagcgcgg gcggacgatt
     4861 tttttctttc cagacatttt ctttcctctt tcttttttta ctttccctca tcttactatg
     4921 ctctagcaaa ataagcaaaa aaggggagaa tagcctcttg caacgactga tcatcgcttg
     4981 atctgttcct tttttactgg gcaagctgtt tgacagtcat cacaattctt accggatttt
     5041 aaacgagtat agacaattgc gcctgcactt ccaaagatta acacacttaa taagaatgtc
     5101 gccatcctat tcctctcctt ctaatgacaa tatagtataa aactggttct tggattttgg
     5161 ctgacggaac aaaacataaa cgagtcctat catcagtaaa atagcaagat acgtccctaa
     5221 cgctacctgt ccaccctcca ataagtgtcc caactgataa atcacaaaac taactaaata
     5281 agctaaaccg cattgatagc ctatggcgat ccaagtccat ttcttggcat tcatttcccg
     5341 atggatagcc ccaattgccg caaaacaagg cgcacaaagt aaattgaagg ctaacaatga
     5401 ataagctgct gcgggagtat atgtgtgttg tagcacttgc cagatttctc tgccattttc
     5461 ggatacttcc gcatgaccaa acaaaatacc aaatgtgcca ataatatttt ctttagcgac
     5521 caatcctgta atcgctgcga ctgttccttg ccagtttccc caaccaagcg gctgaaaaac
     5581 aactgccagg attcgcccga aaaaggctaa gatactttgg tcttcagaaa caggttgagc
     5641 ataaaaatta taagaagagc tgaaccagat cacgatacta gaaacaaaga taatcgttcc
     5701 tgctttttta acaaaagact tgctgcggtc ataggtttgt cttaggaccg ctgaccattg
     5761 aggaaaatga tatgcgggca attccatgat aaaaggagct gtatctccag caaacaaacg
     5821 tgtttttttc aagctgattc cagagaaaat aattgcagtc ataccaagaa aataggcaga
     5881 aggagctacc caagattgat gaggaaaaaa ggcccctgct actaaggcaa taatcggcaa
     5941 ctttgcagaa caaggcatga aggttgtgac catgatcgtc aaacgacgat cttgctcgtt
     6001 ttcaatcgtg cgactggcca tgacgcctgg cactccacat cctgtagcaa tcagcatagg
     6061 aatgaaggat tttcctgaaa gaccgaattt cctgaaaagt cgatccatga aaaaagcgat
     6121 cctcgccata tatccgcagt cttccagaaa gctcaagcat aaaaacaata taatcaattg
     6181 cggtagaaat cctaacactg ctcccacgcc tgcgatgatg ccgttcaaga tcagctcctg
     6241 catccatccc gctacttgcc attcagctaa caatctgcca acatgttctg gtaaccatgt
     6301 accaaacaat gtgtcattga tccaatctgt ccccattgtt cctactgttt gaatagccag
     6361 ataatagatc agccacatca caaatgcgaa gatcggcaag gctaaccaac gattcgttgc
     6421 aatctgatcg attttgtcac tcatcgataa ttggaaagaa tcatttgaca caacacagag
     6481 tgtacatagt tgggtaataa attcataacg ttcattgacc agaatcgtct cactatcgtc
     6541 gtccaatagt ttctctgtta actggatcag ttgctcgatc tctttttgct gagaaactgc
     6601 tatctcgtaa tcctctctta ccttctgatc tcgttcaaaa tatttcattg cataccagcg
     6661 tttcttgccg ctttgttctc ctagtacatc ttcaatttca tgtaaagctg cttctaaacg
     6721 tggatcatat gtacagggaa caggaataga aggccgcttt tttgcagact cctgaatctt
     6781 ttcgattagt ttttcgattc cttgcttttt caatacgctg attggtaaaa ctggtacacc
     6841 aagaccatag gaaagctttt ctagattgat tttttttcct tcttttttga tgacatccat
     6901 catattcaga ccaatgatca taggaatgtc taaatccaat aactgcgtag ttaaataaag
     6961 atttcgttct aaattggtag catcaataat gttgatgatc agttcaggct gttcctgaac
     7021 caaataatct cttgcaatca cttcttctgg tgtataagga gacaaagaat agatgccggg
     7081 taggtcctga atatgaatgt tcggattttt tttcaacgat ccttcttttt tttctactgt
     7141 tacgcccggc caattcccta catattgatt cgaaccagtc aagagattga acaagctagt
     7201 tttcccgctg tttggatttc cgactaacgc gatattcatt ctttttcctc cctttgtatc
     7261 aagattagtt cggcctctga ctttcgtaac gtcagttcat accctcgcac tgtcagttcg
     7321 attggatctc ccagaggggc tagttttcgg ataactattt ttacatttcg cgtcaatccc
     7381 atatccatta accgtcgctt cactgcgcct tgtccgtgga ttgctacgac gatcccagtc
     7441 tctcctgctt ttaattgatc aagagaagtc cagctttcag aggaagcagt ctttttattg
     7501 acaaagattt gacctagtat ttcccgactt actgccactc gatgactttt taccagtaaa
     7561 atggcattgt tgcctgataa attgacgacg acgattttac ttccggcaac gatcccgata
     7621 ttttgcaaat ggcgttttgt tttttcttct gtttcgattc gttcgacttg ataaacgaaa
     7681 ttctgctttg cctgcgctaa ggtctgcata ttgattcctc tcttgtgaaa taaatcatgt
     7741 attaaaatca ttcattatat gttctaattt tcttacgtgt tacgcaaata aatgagaatc
     7801 attctcacat agaatactct cggtaattga gaatgtcaat tatacttgtg atattatgag
     7861 cgaatcttta gtgataaaaa tgagaaaaaa atatttcttc atagttttcc acaatttttt
     7921 ctctattaaa tttgctattt tcccacacga tacttgtttt cagctctttt ttcaaaaaca
     7981 caaaacttag tattccacag tttccacaac acaatatgta gtgtttgttg tttgactttt
     8041 ttactaagag ttttatacta tctattatag ataataagaa tgtgttagag gaggcactca
     8101 ccatgaacgt aaaaatcttt tctaaaaata attgtatgca atgtaagatg gtcaaacggt
     8161 ttttaacaga aaatcaaatt gcttttgaag aagtcaatat cgatgaacag cctgaagcag
     8221 tagactggtt gaaagcacaa ggattccaaa gtgttcctgt cattacttct gatgcagaaa
     8281 cagttatcgg attccgtcct gatcagttgc gtaaacttgc cagctaacat gactaaaaga
     8341 atcaaaacgt gatacatgga tttgaagggc ttgagacagc accagttttt gtcgcaaact
     8401 tccaaatcct tttttaaagc ttaaaaacaa tgcaatgatt tgcaatcaag catcatcaaa
     8461 tacgaaatga aggttgggcg tacgtatgag tcttaaaaat ttacaagatg tcagttattt
     8521 caagctgaat aatgaaatca atcggccagt caatggtcaa atccctttga ataaggataa
     8581 agaagcttta gttgcctttt ttgaggaaaa tgtcaaacca aatacgatga cttttccatc
     8641 tattatggaa aaaatcaatt acttgatcga tcaagaatat atagaagcag aattcattca
     8701 attgtattca ccatcattta ttgaaaagct atatcaattt ttggacgagc aacatttttc
     8761 tttcaaatct tttatggctg cttacaaatt ttattctcaa tatgcgttga aaaccaacga
     8821 cggttccgct tatctggaaa cttatgaaga tcgagtagcc ttcaatgcgc tttactttgc
     8881 gaacggggat gaagaattag cacttgctct tgcagacgaa atgatccatc aacgatatca
     8941 gccagctaca ccttctttct tgaatgctgg acgtaaacgt cggggcgaat tggtgtcttg
     9001 tttcttgact caagtcactg acgatatgaa ctctatcggg cgctcaatca actctgcttt
     9061 gcaattgtcc cgtattggtg gcggcgtagg gattacttta tcaaatcttc gtgaagccgg
     9121 cgctcctatc aaaggatatg agggtgctgc aagtggtgtc gttccagtca tgaaattatt
     9181 cgaagatagt ttcagctatt ctaatcaatt aggtcagcgt caaggagctg gcgtggttta
     9241 tttgaacgtt ttccatccag acattattgc tttcctttca gcaaaaaaag aaaatgcaga
     9301 tgaaaagatt cgcgtaaaaa ctctttctct tggcgtgatc gtacctgata aattttatga
     9361 attgacacgt aaaaacgaag atatgtattt atttagtcca tatagtgtcg aaaaagaata
     9421 tggtgtccca ttctcttatg taaatattac agctgagtat gatcatctag ttgcaaatcc
     9481 aaacattcgc aaacaaaaaa tcaaagcgcg tgatcttgaa aatgaaatct caaaattaca
     9541 acaagaatct ggctatcctt acgtaatcaa tattgataca gcgaaccgcg agaatccaat
     9601 cgatggcaag atcatcatga gtaatttatg ttcagagatt ttacaagttc aaacgccttc
     9661 tgtgattaac ggcaaacagg aatatgaagt attaggaaca gatatctcat gtaacttagg
     9721 ctcgacaaat atcgtgaatt tgatgcaaag ccctaacttt ggtcaatctg tgcgtacgat
     9781 gactcgtgca ttgacattta ttacagatgc atctgatatc gatgtcgtac caccgatcca
     9841 aaacggaaat aagctgaatc atacgattgg attaggtgcc atgggcttac acacttatct
     9901 tgcaaaagaa caaatggaat atggctcaga ggattcatta gactttacaa atatttactt
     9961 catgctgttg aattattgga cacttgttga aagcaacaat atcgctcgtg aaagaaaaca
    10021 agttttccat aattttgaaa aatcagctta tgctgacggc acttatttcg aaaaatacgt
    10081 aactggagaa ttccagccaa aatcagaaaa agtcaaagca ttgtttgaag gcatttttat
    10141 cccaactgct gaagattgga atgctttgaa acaagcagta atgaaagatg gactgtatca
    10201 tcaaaatcgc ttggcagtag caccaaatgg ctcaatttca tatatcaacg atacgagtgc
    10261 aagtattcat cctatcactc gcatgatcga agaacgccaa gagaagaaaa tcggtaaaat
    10321 ttattaccca gcgccttatc tatccaatga gacgattccg tattacactt ctgcttatga
    10381 tatggacatg cgtaaagtaa tcgatgttta tgcaacggca caacaacacg tcgatcaagg
    10441 catgagtttg actttattca tgcgttctga aatcccagaa ggcatttatg aatggaagac
    10501 aacaacgaag caaacgacac gtgatttgaa tattttaaga cattacgctt tccacaaagg
    10561 aatcaaatcc atttattacg tacgtacctt tactgatgat gcagaagaaa tcggaagcaa
    10621 tcaatgtgaa agctgcgtga tctaatatca tagatagatt cgcttattca tattttaatt
    10681 aaaggagcat tctcatgtca gaaacatatt atgaagcaat aaactggaat gaaattgaag
    10741 atatcattga taaatccact tgggagaagc tgacagagca attttggcta gatacacgta
    10801 tcccactttc aaatgaccta gatgattggc gtacattgtc tcaattggaa aaagatacag
    10861 taggacatgt atttggcggt ttgacactgc tagatactgt ccaatctgaa agtggcatgg
    10921 atcagttgcg taaagatgtc cgcactcccc atgaagaagc cgttttgaac aatattcaat
    10981 tcatggaatc cgttcatgcc aaaagttatt cttctatttt tagtacactg aatacgaaaa
    11041 aagaaatcga agaaattttt gactggacaa atacgaatcc ttatctgcaa aaaaaagctg
    11101 agcgtatcaa tgaaatctac aaacacggta caccgctaga aaagaaaatt gccagcgtct
    11161 ttttagaaac attcttgttc tattcaggtt tttatactcc tctttattat ttaggaaaca
    11221 acaaattggc taacgtagca gagatcatca aactaatcat ccgagatgaa tctgtacatg
    11281 gaacctacat cggttacaaa ttccaattag gattcaacga gttacctgaa gcagaacaag
    11341 aaacgttaaa agactggatg tacaatcttc tttatgagct ttacgaaaac gaagaacgtt
    11401 atacagaaga attatacgat ccaatcggct ggacagaaga agtcaagaca ttcctacgct
    11461 ataatgccaa caaagcattg atgaacctag ggatggatcc actctttcca gatactgcca
    11521 atgatgtcaa cccaatcgta atgaacggga tttcaacagg cacaagcaac catgacttct
    11581 tctcacaagt cggaaacggc tatttgttag gtcatgtaga agcgatgaaa gacgacgatt
    11641 atttgattgg attggaataa ggatttattt taattcaaaa atttttcgaa aaataaaaag
    11701 agtttagcgt acagatattt taaatgtaca ctgaactctt ttttatgctt attcacttgt
    11761 ttcttccagc acttttggac tgtctaactt ttccgaaaca tgttccattc ttctcaataa
    11821 atagattttc cggatattta atattatcgt cttaatcact gcatagacag gtatgcaaat
    11881 cagcatgcct aatattcctg cgacacttcc tgctccaatc aataccaaga tgatcgtcaa
    11941 aggatggata ttcattgatt tcccaaataa caacggcttg atcaaatttc catctaattg
    12001 ttggatcact aaaatcgaca acgccatata caaagcttga aatggagaga taaacaaacc
    12061 gacaatgatt gctggtaccg ctccaataaa agggccgaca tacgggataa tattcgtgat
    12121 tccgcaaatg accgcaagca acaagctata aggctgatcg aatattctca ttgccaaaaa
    12181 gctcattaca ccaataatca aagcatctaa gatcgtactg ctgatatagg cagataatgt
    12241 ttcgtttaat tcttttaccg tttggcgtaa ctctttacga atcgctttcg gaaagaagtg
    12301 agacaacgca tcaataaatt tgtgcccatc cttgaacata aatagcaaaa taaatggaac
    12361 ggtaaataac aaaataaaaa attgcatcat aaatgaaatg atttttgaga cacttgcaga
    12421 taaactgact aatatgatat tgaacaaatt actaagagat aaatttgctg atgctaattg
    12481 ttcttccaaa ttgaaatttt taaactcttc ccgctgcgcc aattcattta accatttgct
    12541 tgtttcatct gcatacattg gcaagctctg ggtcaattga attgtctgtt ccattaactg
    12601 aggcactaca ttcatgacag ttaaaacaac taaaatgatt acgaccaaaa acgtcaataa
    12661 aaaaccgaac actctcggga tccgatgctt ttcgagaaaa acaacgattg gatcgaacat
    12721 ataatagata aaaccagcaa caagcaatgg taaaaaaatt gccgaaagca ttttcaatat
    12781 tggactaaaa atattcggca tttgtaaaat aaagtacacg ccgatgatcg tgagtactag
    12841 ctccactgtc cagaaaaata attttgattg tttaaaacgt gattgcatac atctcctcca
    12901 aggtcctttg atacttctat tctatcattt aacaaagagt tacgcgctga gattttcatt
    12961 tgcttaaaaa aaacaaaaaa aataaacata ttttaatgag tagacgagta cttaaacaaa
    13021 aacacggttt ggagtagtga caaaaattat actgcagtcc ctttttccaa ataaacggtg
    13081 ttcaaaagct tgcatcttcg taataagccc agccaaacga aaaatataag gaactatttt
    13141 tatttggctg ggcttattac ttgatgtagg acatctattt tacaacctca gatcatttat
    13201 tgcgcaatac tgactaaatg caactttgtg atatttttgt gtacggacaa ctcctcgatc
    13261 acatcggcat aagtgagccc ttttggaaga tcaatcgtat agatattttt gtacactcgg
    13321 tagtcatcaa cgaattttac gtcaaaattc acatcttcga ttacgatatt tttctcttca
    13381 aaataatcgg taagaaaatc tttggtttct tttctatgga taaattggat ttctaacttt
    13441 ttagtcgtag gtacatggat cacgcgtttc actactgtga gtgcaatagc aatcccgata
    13501 aaactgatga tcgcaatgga atagtaaccc atgccgatgg cgatccctaa tccagcaatt
    13561 gcccataaag aagcggcagt cgtaagtccc gtcaccgatt gtttcgtgac gatgatcgtt
    13621 cccgcgccta agaaaccgac accactcacc acttgagcaa tcagccttgc ttcatctgaa
    13681 cgaatcgttc cagcaagctg tggatactct aaagcatctc ttaatgcacc actagcgatc
    13741 tcaacttgga tcaatgcaat gatacatgct cccatacaaa ctaaaatatg cgtacgcata
    13801 cctgctggac gatttttata ttgtcgttca aaaccgattg ctccgccaaa tagcatagcg
    13861 atccctaaac gtaaaataat ctctggaatt gtcaatacca tatcattcat ctaaacaccc
    13921 tccagtccaa tatatcatgt ctgaaaggag cagacaaaaa aagtgcaatt tttacctctt
    13981 acgaaaaaag gactgtgaca aaatttttgt catagtcctt tttatgaata aacggtgttc
    14041 aatcagctga ccctcggtat tactcaacaa acggcaaaat atggggagct atttttcctt
    14101 tgtcttctct aatactcagg tcaaaacgct gatttcacaa cctctttagc ctactattga
    14161 aaattacaac ttacttgctg cttcttcatc gatgatcaca acaacattgt cgtgattttg
    14221 caatacactt gctggcaaat gattcgttac aggtccttca atcatccctt tgattgcatc
    14281 agctttgctt tcgccaaatg ccatcaagac gatttcttta cttttcataa ttgaaccgat
    14341 tcccattgaa acagcttttg ttggtacatc ttctgcttta tcgaagaatc gtttgtttgc
    14401 attgattgtt gattctgtta agtcaactac tgaagtcgtt ccgtcaaatg aagcaccagg
    14461 ttcattgaaa ccgatatgtc cattttgccc gattcctaag atttggatat cgattggatg
    14521 tgcatcgatg atttgatcat actttttgca tgctgcttcc agatcttctg cttttccatc
    14581 tggtacaaac gtttctttga atggtttttt atcaaataat tggacatcca tgaaatgacg
    14641 gtagctttgt tcatctgaac cgcctagtcc aacgtactca tctaagttta cagaagtcat
    14701 ttcactgaaa tccaaatcgc ttgaagtcat ttctttatat aaagtaactg gtgtgcttcc
    14761 tgttgccaat cctaatactt ttgcaccttt gttcatacct tctttgatga tttcaaatgc
    14821 tttttttccg ccttcttcag cgttttttac acgaatgatt tccatagtga ttgctccttt
    14881 atattttggt atagcccaat tatagcattc tttttttctt tttacaataa ttagtataga
    14941 ccaaattgca tttttttcat tttcttgaca ataaatagga atccgtgtta ggtttcataa
    15001 gatggttcaa tcaaacaatc catgttgcat gaaaaccaag caagtgattc actgtggacg
    15061 ctttatgtct gcagtttttt tatgaaaaag gagttattat gagtatactg acattaaaca
    15121 acattaccca gcaatttggc gacaaaatcc tctatgaagg tgtcgatctg caattaaatg
    15181 ctggcgaaca tcttgggctg attggacaaa acggagccgg taaaagtaca ttgattaaaa
    15241 tcatcactgg tgagatctta ccagatgacg gacagatcca ttggcaaaaa aatattcaca
    15301 aaggttacct cgatcaatat gtggaagtcg atgaaacatt aacaatcgaa gaatttctaa
    15361 aaactgcgta cgcaaaagaa tacgaaaagg aagaaaaaat tgcttttctt taccaaacat
    15421 atagcgagac cttcgatgat tccttgctgg aaaaagctgg gaaactccaa acggaattag
    15481 accaaggagt gttttatcaa atcgacacct tagttgctga gatgagcagc gggttgggga
    15541 tcgatgtctt aggtttagat tcactgttga aaaatctaag tggtggacaa cgttcaaagg
    15601 tgattttagc aaaactactt ttagaaaacc cagatgttct gatcttagat gaaccaacca
    15661 atcacttaga tgatcagcat atccaatggc tgacgcagtt tcttcaggat tttgacggtg
    15721 cgtatatcgt gatttcccat gaccaagaat ttcttgatca gatcaccacc catatcgcag
    15781 acatcgagtt tggaaagatt actaagtata ctggccatct aaaacaagca ttgaaacaaa
    15841 aggaacaaaa tcgcgaaagc tatttgcgcc aatatcatgc tcaacaaaaa caaatcgaaa
    15901 agaccgaagc ttatattcga aaatacaaag ccggttcccg atcaacgatg gcaaaaagcc
    15961 gacaaaaaca attagataaa atcgaacggc tgacgcctcc agcttcagca agtaaagctg
    16021 tctttgattt tccattctcg cctattgtca cgacattagc agtggaaaca actgatttag
    16081 tcatcggata tgatcgaccg ctacttgcac ccatcaattt gaccatccgc tttggtgaaa
    16141 atattgccat tcgaggcttc aacgggattg gaaaatctac tttattaaaa acactgatcg
    16201 gtgagattga aaaaataagt ggcgatttcc acttcccaga taacacaaaa atcaattact
    16261 tttcacaaga tctgtactgg gaaaatccat tagaaacacc actacaatat ttaagcagtc
    16321 aatttccaaa agcgactatc aaagaattac gtcgccaact agctaaagca gggttagtta
    16381 atcaattagc aagtgaacct ctcactacat taagtggtgg ggaacaaact aaggtgaaac
    16441 ttgcacagtt gacaatgaac caaggtaatt tactgattct cgatgaaccg acgaaccata
    16501 tcgatcaaga aacgaaagaa agcttacaag acgggataca gaaatttcca ggaacagtaa
    16561 tcatcgtctc tcatgaacaa gaattttatc aagatcttgt gcaacgagtc attgagattg
    16621 aaccaaaata aacgtttgat tgaatagttg aaaaaaagga gctgtgacaa aagttttgtc
    16681 acaactcctt cttctgaata aatggtggcc aattagctga ccttcggtat tagctcaaaa
    16741 aacggcaaaa tatgaggagc tatttttatt tggctattct tattacttga tgcagaacag
    16801 cttttcacaa cctcttttcg tctatttttt attttcgaga tttctctttc ctttaaaaac
    16861 aactgtttga aagaagaacg cacatccttg aaaaacaagc ccgctaaccg ttacacctaa
    16921 ccagccatac tgctgccaca ttgtcgtccc tagcaatgaa ccagccgcac ctccaataaa
    16981 gtacataaac ataaataca
//
LOCUS       DARPZF010000053        16669 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.056, whole genome shotgun sequence.
ACCESSION   DARPZF010000053 DARPZF010000000
VERSION     DARPZF010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16669
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.056"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..1350
                     /locus_tag="SLE65_002212"
     CDS             <1..1350
                     /locus_tag="SLE65_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEI8449483.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1484..2827
                     /locus_tag="SLE65_002213"
     CDS             1484..2827
                     /locus_tag="SLE65_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEI8449484.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            2939..4390
                     /locus_tag="SLE65_002214"
     CDS             2939..4390
                     /locus_tag="SLE65_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HEI8449485.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            4739..5371
                     /locus_tag="SLE65_002215"
     CDS             4739..5371
                     /locus_tag="SLE65_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HEI8449486.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            5959..7398
                     /locus_tag="SLE65_002216"
     CDS             5959..7398
                     /locus_tag="SLE65_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8449487.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            7693..7911
                     /locus_tag="SLE65_002217"
                     /pseudo
     CDS             7693..7911
                     /locus_tag="SLE65_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8160..8375
                     /locus_tag="SLE65_002218"
     CDS             8160..8375
                     /locus_tag="SLE65_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449488.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(8592..8848)
                     /locus_tag="SLE65_002219"
                     /pseudo
     CDS             complement(8592..8848)
                     /locus_tag="SLE65_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9035..9946)
                     /locus_tag="SLE65_002220"
     CDS             complement(9035..9946)
                     /locus_tag="SLE65_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEI8449489.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(9965..10969)
                     /locus_tag="SLE65_002221"
     CDS             complement(9965..10969)
                     /locus_tag="SLE65_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEI8449490.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(10966..13089)
                     /locus_tag="SLE65_002222"
     CDS             complement(10966..13089)
                     /locus_tag="SLE65_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEI8449491.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(13094..15541)
                     /locus_tag="SLE65_002223"
     CDS             complement(13094..15541)
                     /locus_tag="SLE65_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEI8449492.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(15528..15917)
                     /locus_tag="SLE65_002224"
     CDS             complement(15528..15917)
                     /locus_tag="SLE65_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEI8449493.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(15977..16480)
                     /locus_tag="SLE65_002225"
     CDS             complement(15977..16480)
                     /locus_tag="SLE65_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEI8449494.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(16493..16654)
                     /locus_tag="SLE65_002226"
     CDS             complement(16493..16654)
                     /locus_tag="SLE65_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449495.1"
                     /translation="MAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGVKDVLL
                     SLFNRIVGA"
BASE COUNT         5384 a         3110 c         3069 g         5106 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1501 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1561 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1621 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1681 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1741 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1801 agttatatta gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc
     1861 taatattttt tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga
     1921 tagtactatt aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga
     1981 agccataaga aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc
     2041 gacttattac gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat
     2101 acatctttgt ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat
     2161 agtcactaca agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct
     2221 atctaatagt ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac
     2281 taatgaatac cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac
     2341 tttttttacg tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac
     2401 agcttatatt gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt
     2461 tacaaatggc ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac
     2521 agcacgatta ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc
     2581 ttttttgaga aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag
     2641 aatagtaggt gtacaacttt gtagtcaaga agatttatct ggactattat caatgttttc
     2701 tcttgctata gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca
     2761 tcctagtttt agccaaccct ataattttat tttaaaggca gtaacaggat taaacattga
     2821 aacataatcg ttactaaatg aaatcaagaa atatactgta ttactcaatt cattgaaaat
     2881 atttatcata atttttaata gaaaacacta ttaaagagaa aaaagagagg taaatcaaat
     2941 gaaaaaatct ttaaaacttg catcagcagt tatattaatg tcccaactcc ttatagcaac
     3001 acctttccat gtgttggcaa gcgaaaattc aacatacaaa attgcaaaag aaagaaccga
     3061 gacgactgaa atgagtaatt ccgatgtaac agcagagagt agtgaacttt tgacaacttc
     3121 atcaagtgaa agtagtacga cttcaaatgc cgagtcttca acaacttcat caagtgaaag
     3181 tagtacgact tcaaatgccg agtcttcaac aacttcatca agtgaaagta gtacgacttc
     3241 aaatgccgag tcttcaacaa cttcgtcaag tgaaagtagt acgatttcaa gtaccgaatc
     3301 ttcaacaact tcaagtagta caagtgaaat aacttcttcg aaagtgacaa aaccaaacca
     3361 tatagaatct tcaaaaaagg aagcgccaaa aacggaagga caaacaaaaa ctttttcgac
     3421 accacagcaa atagaatcaa cagaatcttt ccaatcacaa ccaatactat ctggtaatga
     3481 agaaattcat tttgacaaaa atgaatctgt agaaaatttt attatgaaaa ttggtgagtc
     3541 tgcgagaaaa attggtcaga aatatgattt atatgcttct gttatgattg cacaagcgat
     3601 cttagaatct gccagtggtc aaagccagtt agctcaggca ccgaattaca atttatttgg
     3661 gataaaagga acttataatg gaaactttgt cattatggta acaaacgaag atttgggtaa
     3721 tggaacgctt tatacgaccc aatcaaaatt tagagtgtat gaaaactatg aggaaagctt
     3781 tgaagattat gccaaattat taactaaggg aattagtgga aataaagatt tttatgcagg
     3841 agcattaaaa gctaatagta aaacatatcg agaagcaact aaattcctta caggacggta
     3901 tgcaacagat acacaatact atttgaagct aaatgaatta attaaaacct acgatttaac
     3961 caactatgat aaagaagtta aaggtccaca aatgagtaag actggatacc aagtgcctat
     4021 tcataattat tcaataacca gtttgtttgg aaatcgtgga aatgaatttc accgaggact
     4081 tgatatggca gctacacagg gtgagccgat tcatgcagtt aaagctggta aggttgttaa
     4141 agcagagttt cactactctt ggggaaatta cgtggtgata caacacgaag atggatcaac
     4201 cgcgttatat gctcaccagc aacaatacct agtaaaaact ggagataatg ttttgcaagg
     4261 acaaataatt ggctatgtag gaagtactgg gaatagtact ggcccacacc ttcatttgga
     4321 aatttgcaaa gatagtagtc tttctcagag catgttagtt gatccgaaaa ccttattatt
     4381 cggagactaa aaaaggtaat caatctgaca aagtaacaag aaaatggttg gattcttaga
     4441 cctttgatca ggatattgag actggaattg atatctcgat tacgatgggt ttgacaaata
     4501 aaacaagtcc attatcgaat atcgagtgta ttattgccgt ctttatgctc atattttgag
     4561 caggtttcac tagatgaaaa caatttatct atcttgagga tttcgtgtac gtatcgttca
     4621 gtcttgtatt gtaaattagt cataaaatca gactaagaaa aattggaaat atttttttct
     4681 gatttattaa aagttaattg aaattatatg gtacttcttt cttgggaggg taggtgcagt
     4741 gaaggaaaga tatggtcacc ttactgttgt tgaggagatt actcataatg gatataaaaa
     4801 atatcgttgc ctatgtgact gtgggaatga aacgattgta tatcgatcaa acttactatc
     4861 aggtagaacc aaaagttgtg gatgtggaaa ttataaaaat aggcataaat ataaaaattt
     4921 gacaaataaa acttttggta agttagttgc aatcaagcca actaaactgc gaagtgaagg
     4981 aactgttgtt tgggaatgtc aatgtctgtg tgggagaaaa aagttagtat cggcaaagcg
     5041 acttctaaaa ggtgatgtaa aaagctgtgg atgtttgaaa tcaaaaaagc atcacattga
     5101 aaataaaaaa ttcggattac ttactgcaaa gtatcctttg gacaataact gttcatggaa
     5161 aacaaaatgg gtttgtcatt gtgagtgtgg cagtatgtgt gagataagtt atagtaactt
     5221 attttttgga catactcaaa gttgtggatg tttaaaaagg caagaaacaa ggacatgtgt
     5281 tgaagggaca gtaatagagt gtctaacgtc aaaattaccg aaaaataata caagtggtgt
     5341 taagggagtt tatcgttcta aagagaaata gattgcgtat ataactttaa aaaaaaagag
     5401 gtactattta ggatcgtatg attctattaa gagtgcagct caagctagaa aagatgctga
     5461 aaataaattg tttcaacctt tgattgacaa atatcgaggt aatcattaat tattgtggat
     5521 aataattaac agtgatatat aaacatctat aatatattat tcatactatt gatatttagt
     5581 ataatcctat ggaattgaat atcatagcaa tgtatttgaa aagcaaattg gaaaacaaat
     5641 aggtgcaaca ccataaatat gaaaaaattg ggaaaaagta gaatggaaat ttgcttacgt
     5701 ctcacgagat agctcacact attaatctga agaacaatga agtcgacttt tagaaattgc
     5761 tagaagaaag taaagcgaat tatcactagt tactatagag taagttcaaa taaagcatct
     5821 ccaacttaca tggttacatg aggatatcaa atcgaaatta ctcaagcttc ctatggctag
     5881 agtcgcgaga agttgttggg cagtagacat aggttatatt gttcttagct acacgatcat
     5941 tagaaaggaa atcctattat gtatagttat caagaagatg caaaagtcca aaaaaatcgc
     6001 tggtggattt tgattgctat atctatgttt accttcatgt ccacattgga tggcagtatt
     6061 gtcaatattg cactacctac catctcagat gatatgggca taccaatgaa tcaagcggaa
     6121 tgggtagtgt ccgtttatct gatgattgtc tgttcttgtt tgttgctgtt tggtaaaatt
     6181 ggcgatagcc gtgggaaaat caaagtattt cggattggta cgctgatctt tgtcttggga
     6241 tcgctgttgt gtgggttcaa tcattcgcta ggtattttat tgttcgcacg ggtggtacaa
     6301 gccattggtg ctagtatgac tatggctaca aatgccggaa tcatcacgga agtctttccc
     6361 atacatgaac gtggtcgggc attgggagca ataggtgcgt ttgtttcatt aggctcgatt
     6421 gctggaccag gtcttggcgg cttgattttg tcccaatttt cttgggcgta cattttttgg
     6481 atcaatgtac cggtgggaat cgtaacgatg ttgattgctg aaaaattctt accaaaagat
     6541 atcaccatga gcggccatac aatcgatgga gggggctttg ctgccattgc ggctacgatt
     6601 atcagctttt ttggagcaat ctttttgggg caagaaagtg gctttttcca tccagtcccc
     6661 cttgtactgt tcgtaatttc agtgattgcc tttgtcagct ttttaaaagt tgaaaagaaa
     6721 gcagcctctc cattgatttc tttcggtatt tttaagaaca agatttttac catgagcttg
     6781 attacagcct tgttgatttt ttcttccaac ttctttgtca atgtagtgat tcctttttat
     6841 ctgcaaaatg ctcgcgggtt gagtcctagc tatgctgggc tgttgatgat ggtctttcct
     6901 ttgatgatgg tcgtcggggc gcctttaagc ggctacctga ccgaccgggt tggcccggag
     6961 attttggtat tagtaggctt gggcttattg tcggtaaccc aggtcatgta tatgtttttg
     7021 tcagtggact ctcctttgtg gctatacatt gtcgctactg ccatcatggg tgccggcaat
     7081 gccttgttcc agtcccccaa taatacgatg gttatgagct cggtcactat cgaaaacttg
     7141 ggactggcag gctcgatgaa ttcctttgcc cgaaatttgg ggatggtcag cgggatttcg
     7201 ctttctacga cggtcttata tcaagcgatg tctgctaaga tgggccagca agtaactaac
     7261 tatatcgcaa atcggccgga tgtcttttta tatggaatga agattacctt tttaggcagc
     7321 tttgttttgt gttttgttgc ctttttcctg actatctggc gtatcaaaaa acaaggaggt
     7381 attcagaaaa atgtctgaaa aaaccactgt tgaagaattt ttggaggcct gcgtatgggt
     7441 gagtgggatt tccatggatg atggaagatg aagtgaactt ctaaaagccg aaaaactcaa
     7501 gtattatctt caaaatacta gtgctcaatg agatgcttga tttgatcaca agaagactgc
     7561 gaaagccgct ggcaaccgca agctaggtat cccaccgatg gactacgttt tagaggctac
     7621 tggttatgaa tacggagcca acgctctcat ctgcataaga atacatcacc cagattatgt
     7681 aaagattttc gatacttctg tcaaaaaatc attaagatag ataaatgatt tccgtctagt
     7741 caaattggtt cagaatgtag acacacagat ggtaagaagt cactcacaat tcgagaatgg
     7801 acttgtccta tttgccgtat acatcataat cgaaacgtca acgatagtat caatattttg
     7861 accaagggct atgaatacaa gcattgcctt agaaaacatc aagaacctta ggaacaacgg
     7921 ggatagcttg gttaataaga gataccgctg tttaggcttg caagtatact cttttatcaa
     7981 gaattccgtg gctttagtca tgagaggctt aatactatga aaattttctt tagcattttt
     8041 gatttaggtt ccttttctaa ttataataag atgaccacta cagtaaccta ctgaaatata
     8101 taaacagcca ctgtagtacc attttcaaag tagtctatga gaggagaatc ttcattctta
     8161 tgaacgctgg aattgcggat atgaatttaa taaaaaaaac ccttaatgat tttacttcca
     8221 attcaatatc aaaaggtact ggtatcaatt taagcacaat aaaaaagctg aaaagtggtg
     8281 aaagatcagt ggaaaagctg aatcttttag atgctataaa aataacggaa tttgctatga
     8341 aaaatggaaa agctgagatt gaaatatgga gataattatc gtctagtgaa ttacttgcca
     8401 cttagctgaa tttaacgatc cttggtgctt gaagggggag attcttggga atagagcata
     8461 cttgcaagcc tatgtcttta ctaacaacga tatctcttat taaccaagct atccccgtag
     8521 ttctaaggct tttactttta tctaagcaat aatcgtattc aaaggaaatt tttgaccctt
     8581 agaaagtctc attttatcag acgtgagctt aggcattgct gaattttgtt aattcggttt
     8641 taggttgtgc tttgagcata atatgaaagt attctttatc acgatttcat tcatctaagg
     8701 taatgtgatg tgattctgaa attctttcaa aggcagtttt tgcataagct gacattacat
     8761 catcaatgac atgtttacaa tgtttcacta ctaaaataag ggggtaacca agaagaaaaa
     8821 ctgaatgatt atttgtatct aattccatgg tatatcaacc atttcctata tagactgatt
     8881 atgacatgga ttaaaataaa aaggcactat gtcttaattg tcggttttcg agttaccgaa
     8941 tggcattcat cacccaccta tagaggatgg gcgacttctg cctgaaataa gttacactac
     9001 ttataacttc taataaaatt agattgagtc attattattt aacatcaacg attttccagt
     9061 ttccattttt ttgtaatact aatttgtact gaaagtagct agtggttttt gatacattat
     9121 caaggtattt tatctttgta ctcactagaa aattttttcc gttttgtaga taaactggat
     9181 tctctaactc cgaaaacttt aagtcaatat tgattggtcg catcgcacca ttttcaacat
     9241 aatactccaa ttctttttca gaagctgatg gataaagttt aaaaaatgtt tctaaaaaat
     9301 cggtgatttc ttccgttgtt ttggcatcaa tttctgaatc gttttctact tgttttgctt
     9361 catattttgc cttgtctggc tttccaatca ttgttggcaa actagttact aaatgattcc
     9421 tgttttcatc ttcaaagatt gtcactcgat atgcagaaga aattgattgc gtcttttttc
     9481 cctctgtaat atgttgctcc actaaaaatg aaacgacaaa ttcttccgag tgtttttcaa
     9541 catctagaat ttttacagat tgaacttcgg aactcgtggg aatatctgct cgaaccatat
     9601 cttggattaa agcgagaccg ttttctgtaa ggtactgttc gagattactc attctctttt
     9661 caattgcttc tttgttattt ttccatgaaa aatattcttt cgcaaaatcc tctgtaaaac
     9721 tttcaacgcc agaagtattc actaccttct cttttataac cactttttca tgagttgtat
     9781 gttgatcaat ggcggtgaaa tttttataaa cgccaaaagc aagactacaa gacaataaaa
     9841 gccaaagggc aagcaccatt tttcgatgct tacccacgga tacaactcgt tcttttttct
     9901 tttttgggct cttttccttt tgattccgtt caatttttat cttcattctt tttcctcttt
     9961 tctcttattt gtatcggcca gctccgataa gatgctgccg ccaatagttt tccgttagat
    10021 tcgtccaccc cactggatct cctgcatgaa acatgcgatt ctcccctgcg taaatgccca
    10081 catgggtcac ataagtaccg gcatcatagg ttgaatgaaa gaaaactaaa tcacctggtt
    10141 tggcatcttt tagatcaata tgagtcatgg catcatattg atcctgagcc acccgaggaa
    10201 gtttcaggtc aactttggca taacaccatt gggtcaagcc actacaatca aaccccgttt
    10261 ctggacttga gccaccaaac acataggccg ttccttcata cttaaatgcc tcatcaaaaa
    10321 tttcttggac tattttgtca tcaaactgag ttgtagttag gtattgcttc actaataaac
    10381 agtaaaacat attgccataa ttataccgcc acccaccatt ttccttaatc gcgattgggt
    10441 tggggtaatc gactttttga ccacctgatt tttcctttga aaaagattca gctaaagcaa
    10501 aactatgctt cttcccgttt ttcccgacat gatctagata cccgccacca tagttatagg
    10561 cctgaataat actatcttga tcacacccta gttctttgga acgcttaacc aaagacgcaa
    10621 aatagagaca gccttgtttg atggatgcct cggtacttaa tgaattaggt ggtaatccgg
    10681 ctgactcaga actttgcata acgtcttcca ttgtgccacc agattccact tgaataatcg
    10741 ccaaaagaat tggaatatac tctgttatat ccgattcttt ggcatacttt tccaccattg
    10801 cacggtgttt caatacttct tctgagacac tagttccgcc aggagaagtg ccagaactac
    10861 catttccctc actgtcttca ccaaacaaca aacccacaca catcaaaata cccataaaag
    10921 agatggtcag aaaagttaat gaaataacac ccactttctt caagttcatt ttttctcacc
    10981 tgaccttgat tttggacgat ggttcattct tttttgtact ttttgattgg tctgctttgg
    11041 cagagtggac ctctgtttca cttgttggaa agaatttttc ttacttgctg attggctttt
    11101 cccttttgaa atgatttctt gactagttag ttttcgtttg atttcgggat tcagatttgc
    11161 tctcacaatc cgctttggtg cttctttttt cagcatcata tctttctgag gttgagctgc
    11221 tttatctatt ggaatattcg cccttctttt tccctgacga tttgttgctt cactcagtat
    11281 cttgcgtttt tcgtccattt tcgcatttct tcgttgtcgt tgtttttctc gcaaatccac
    11341 tcgatccgct ttttcttgga acagtccgcg cttgaattct tctggtgctt ttttcgactt
    11401 ttcgattcct ttatggagat tgtatttcaa attcgttggc gtattcctta cctgatcctt
    11461 tacttgttta gtcttatctt tcaccaaagc ttgggtatcc aaaactttgc cgatttttct
    11521 cccagccaaa ttcattcggg attgtttctt attatttgaa actggattct ccttagttaa
    11581 gtcagatagt atttcgtgat cgttcggtaa tcgtgaattc tttcgtagag aagaaccgga
    11641 tggcttaaat ttggattttg attgttcctt tgccaactta tttccgactg ctgcaccacc
    11701 accaaaagcc aaagctcgtc ccacatttcg attgagttgc cgcaattttc gattcattaa
    11761 catttgcggt tttcgcatga cgcgtcttcc cattgactgg ctatcattac tctggaggtt
    11821 gaacatactc ataatgtcgc ccaatttgaa atagataccg gcaaaggtca caatttgcag
    11881 aaaagcaacc atgaaaaatg gataggttgc cgaaatattg aaaaacatcg tggagatgct
    11941 aaatgcagtc gtaatcacca aagtaacacc cgctcgcatc ataatcgtat tgaataaacg
    12001 aataatcgcc ttctttccta aactttcata agtcggcaac atggacaata agaaactaat
    12061 tggcagaaac atcgcaaaga taatgaagag aatttgcgag aacaacataa tccctgttag
    12121 aagaaaaaca aagaaggaaa tgccaatatt gaacaatacc aaaaagacca cggtccctaa
    12181 acggttcatg gtcttggtaa tactgagatt cgcattgtca ttgtcttcaa tctctgcctt
    12241 gaccgcttct tcccgatctt tgcctttgtt ttcatctgga ctcacagata gaatcttgtt
    12301 gacccggtct tcaccaattt cttctatgtt ggaatcatca aattgcagta gtaaccaagg
    12361 ttgttggact tgaatcgaaa acaaactatc ccgaatcaaa tccacactat cttttccttg
    12421 gctttctgaa ttgggtacaa cgatctcggt tccaagggta agggccgctt cactaacatc
    12481 tgagctaaag tcattgattt ttgtgatata ggtaggcgca taagcaatga acgaacccga
    12541 tagtagaaaa atcatcacaa aattaatcac ggctcgaact gctttcgtgg tttctcgttt
    12601 taataatccg gtatacgcca catacacccc cagagctaaa atcatcaata atagaaaccc
    12661 aaaataaaat ccggaggtct ggagtccatt ttcagtaata ccagccaatg tttggatatt
    12721 ctttccaata ctttcagccg tatccgaaat gaaatctaat ttgtaagcct cttgaaccac
    12781 ataacccgtg gcgttcgaca aatacaaact caccgtccaa atgaaattag taatggcata
    12841 aagaccatac atcacgcttt tccctaagcc atccccccaa ttccaaggca accaatccca
    12901 agagctatcc acaaagaaat ctagttgata gttgttcagt gaatatttgg aatatagatt
    12961 tcctgcttca actgtatcat caactagccc tgtcgcctcg gctaccgtac caactaaact
    13021 caatagaact atcagagtga gtatgctaat aaaaacgatt cccacaatcc gaaaaagttt
    13081 ctttttcatc ccctcactcc attctctctt gaacaggtgg acgggtatca aaggcatgga
    13141 agagttcttc aaagactgga tgtacctgaa ccacgcctac ccgaccatac aaatcctgca
    13201 tcaagcattg gccattttcc aaatctcgta ggcgtttttg attgctttca tcttctcgat
    13261 ccaagccaaa gaattccaag gttttcttga tttcatgaat atcggtactg cgaaacgcaa
    13321 acttcaaccc gatattattc ttcaagcgtt catccagtaa atcatcacta ttttgcgtga
    13381 caaagtaaac cccggcattc atagcccgcc cagcacgaac gagcttattc gataatgttt
    13441 tcccttgcgc tacttgaaga aaactccacg cctcatctaa gtctacaatt ttgaagattt
    13501 ctcgattact atggataaag tccaaggcaa aagtggaaat gacgattagc atggaaacac
    13561 taagcaattc catggtggta tattcttcaa aagtggtttc tgcatctggt aaaaccaaat
    13621 ccgctacttg aatgatattt aactgcctat ctaaactaat cgactgggta atcgaaccat
    13681 ctgagaaaag caaatgggca aaatcataat cggtaaagga ctcgatgtga tccgcgatat
    13741 tttccgcaac tggtgagcct tcttttcgaa gctcattaat tacttgtaat aatccccgtt
    13801 gattgctttg ggtaaccgtc cgaatggcct tacgcaacac tggaaacttc tccccatctc
    13861 gactagaaat tcctgttaaa aaggtcagaa tatcaattgc tagactttca gaatccttct
    13921 ttttctccat aatcacataa ggatcaagta atccttgatt ttttggctta ctagttaagt
    13981 tgagaatatt gatttcatcc gcaatttctg gcaaggtttc tttccagcca ccccgttccc
    14041 cttttggatc gacaatcaca gcttgtccac caaaaaggac ggcgtaataa actaagagat
    14101 tgttactaaa ggactttccg ccaccgagtg aaccgaggaa tgccgctgct agcgcattgg
    14161 taactgaacc cttgacccct tgtgaggcca atgccggttt caggtaaaca ttgcgccccg
    14221 tatctacgtt ataaccaaag taaatgcctt ccaactcccc taacatctga gtggcgccaa
    14281 aaccaagtcc ggcgagaaaa tcagacgtaa catactggat ataatcattc atgtatcgct
    14341 tactagaagg taagaattct tcatgtagcc ccatcatatc gccaaaaggc cggactagtt
    14401 ttacattggt atcatcataa aaatctagca cttcatcaca ccggcgcttt agttcatcta
    14461 ctgattcggc acttactcga accacatagc tcagtttgta catggattct ttggactgat
    14521 ccaaggtagt ttccaattca tctacggaat ccaatgcatc taagacattg gaatttgttt
    14581 cattgtcaga ttgataggca tggttgtcca agtcttttaa ttcctttttc ttattgcgaa
    14641 cggtagcaag tgcctttttg ttcgtcacaa tctccacatt catactagtg tcaattggga
    14701 atgtaaattg ttgttgctgg taatagaaaa gttctgagga gggaaactcc atttccccca
    14761 caattgtatt aattgttaag tacgctacat atgattcatg attctcatgt tccatgcata
    14821 agtaccgggg cttttcttca atcaaacaac gactgggacg taataagtcg taacgtttca
    14881 ccaaagtttc cgacttcagc tttttctttg gtagctgaaa ttcatattct tcaaatggtg
    14941 tacccttttc gccatagata tgttcaatca aatacatcag atcactcggt gtgactcgtc
    15001 tgactttaaa tcttcgagcc aatttacttt ccattagttt ttcaagcttg gtatatcggc
    15061 gaatttcttc attggataag gaaacaaaat cgcccatcaa atgatgattc actccataga
    15121 caaattcttg aaagccggag aagaaagatt tcttgagatt ctttagattg acctcttcat
    15181 ctgtcgcaat cagtttgaag ccaataaaaa agcgataatc aatctgacta tcgccaatca
    15241 tggatactaa tgcctctgtc tgtaaatcaa ttcgttgttt cgctacttct gttaatcgcc
    15301 cggtaatttc cttttttgat cgttcttgcg tggcacgaat actactttct gtggcaattt
    15361 gtaaggcatg aatcttgcct tcacgatttt gcgcaatcaa ttgacgaaag ttatcgtgga
    15421 cttgatattt ctgttcaggt gacaaaaagg agtaattgta aggtattaac tcatagtagg
    15481 caaaacattc tccctcttga ttaaagacaa gattattttc aatatactta atcgggtaca
    15541 tagttcacac tccttaccag agtaatgggt tcgtcccatc gtttcttctg ttctttgact
    15601 ttctttcctg cgaaagtgac cttaaatcgt aagtgatagc taataaaaga tcgtaaaaat
    15661 cccaatggtt tcttaccgtc aaacgttttt tgcgacatga accaagtaac tgccaccggt
    15721 atacctaagt attttaaaaa ggccccctct atcatagata gtggaggcac atgggcaaat
    15781 acgatgacaa acagcaagga taaaacaaac caagccatct ggttaaaagt cacaggaaaa
    15841 ggcagttgaa agtcattaat tgcataaatg accttttcaa ctgcccaaat actggtgtag
    15901 ctttttattt tcttcatcaa atcattcctt taaaaagaag gatagtttag aaatcaacta
    15961 cccttcaata attttgttaa tatggatact caaaaacacc tcgactcgtt accaaataat
    16021 tgcctccaat ctccaagtct ctaccacacg catcaaaatc aatatacgtc ttcaagtgtt
    16081 ctggtacttc tccaaaatca ccagcttcta caatcaagaa atatgctaca tcactcatat
    16141 catcgcaatc tggataatag ataatatcat ccacatgctc taccatctcc tcaaaagaat
    16201 tgaagaaagc atgttgaatc tcagaagcaa cttcaccaac tggcgttcct tcaagttcct
    16261 ccgctaagcc acacaaccga ttaatttcct caattggcgt atactcatca atctcaaagg
    16321 gaagttcata atcatgaatt gcatattcct cgtattcgtc atttaaccca attcgttctt
    16381 tcacttcatc aaaatcgaca ggtggggtaa accacgcccc caccaattca ccttcgttat
    16441 atttcccgag gttcgcaata taaacacgca tctgttccat cgtgcttccc ccttacgcac
    16501 cgacaattcg gttaaacaaa ctgagtaaga catccttcac cccagaagca ttaaagacca
    16561 atccgaccgc aatcaaagca atcaccaaaa agccaatcag tttggaaaac tcccgcttaa
    16621 atcctaaaaa caaaccaatg accacaattg ccagtaagac taaggattg
//
LOCUS       DARPZF010000054        16585 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.057, whole genome shotgun sequence.
ACCESSION   DARPZF010000054 DARPZF010000000
VERSION     DARPZF010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16585
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.057"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..495
                     /gene="scm"
                     /locus_tag="SLE65_002227"
     CDS             <1..495
                     /gene="scm"
                     /locus_tag="SLE65_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HEI8449496.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSK
                     TSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYK
                     KSKR"
     gene            complement(650..1636)
                     /locus_tag="SLE65_002228"
     CDS             complement(650..1636)
                     /locus_tag="SLE65_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEI8449497.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1659..2225)
                     /locus_tag="SLE65_002229"
     CDS             complement(1659..2225)
                     /locus_tag="SLE65_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HEI8449498.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2239..2655)
                     /locus_tag="SLE65_002230"
     CDS             complement(2239..2655)
                     /locus_tag="SLE65_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HEI8449499.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3112..5046)
                     /locus_tag="SLE65_002231"
     CDS             complement(3112..5046)
                     /locus_tag="SLE65_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEI8449500.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5327..6283
                     /locus_tag="SLE65_002232"
     CDS             5327..6283
                     /locus_tag="SLE65_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HEI8449501.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6373..7476
                     /locus_tag="SLE65_002233"
     CDS             6373..7476
                     /locus_tag="SLE65_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEI8449502.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7489..8442
                     /gene="menA"
                     /locus_tag="SLE65_002234"
     CDS             7489..8442
                     /gene="menA"
                     /locus_tag="SLE65_002234"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HEI8449503.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9377..10723)
                     /gene="gor"
                     /locus_tag="SLE65_002235"
     CDS             complement(9377..10723)
                     /gene="gor"
                     /locus_tag="SLE65_002235"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEI8449504.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10857..12110)
                     /locus_tag="SLE65_002236"
     CDS             complement(10857..12110)
                     /locus_tag="SLE65_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEI8449505.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(12116..13039)
                     /locus_tag="SLE65_002237"
     CDS             complement(12116..13039)
                     /locus_tag="SLE65_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEI8449506.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13260..15752)
                     /locus_tag="SLE65_002238"
     CDS             complement(13260..15752)
                     /locus_tag="SLE65_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEI8449507.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15759..16226)
                     /locus_tag="SLE65_002239"
     CDS             complement(15759..16226)
                     /locus_tag="SLE65_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEI8449508.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(16362..16435)
                     /locus_tag="SLE65_002240"
     tRNA            complement(16362..16435)
                     /locus_tag="SLE65_002240"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16399..16401),aa:Arg,seq:acg)
     gene            complement(16493..16566)
                     /locus_tag="SLE65_002241"
     tRNA            complement(16493..16566)
                     /locus_tag="SLE65_002241"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16530..16532),aa:Pro,seq:tgg)
BASE COUNT         4897 a         3467 c         2954 g         5267 t
ORIGIN      
        1 acatcagctt caagtgacag tacagatact acctctacca caagtgatag cacggacacg
       61 tcagcttcaa gcgacagtac ggatacatct accacaacaa gtgatagcac ggacacgtca
      121 gcttcaagtg acagtacaga tactacctct accacaagtg atagcacgga cacgtcagct
      181 tcaagtgaca gtacagatac atcctctacc acaagtgata gctcagattc atcaacttca
      241 agcgatagta cagacacgtc gtctaccaca agcgatacac gtcatgcaag tgtctccttc
      301 tcaaaaacaa gttcggataa caggacgaac tttaacttaa ctaataaaac aagcaatgac
      361 aatggaaaca aatcaaaaag agcacttcct aaaactggaa gtcaatcgaa taattggata
      421 acactcgcag gcgttatatt acttgtaatc ggtttaagaa tcacttttat gagttataag
      481 aaatcgaaaa ggtaaaaaaa tattcaagat aaaaaagagc aacgtcgcta acggacgttg
      541 ctctttattt ttgcttttta tcataaatac aagaactaca attcaatttg tcaaaaaaca
      601 cgtagatttc cttctgagaa atttatttac gtatcgaacc tttccctatt cagtctttgc
      661 gatccaaaat cagttgggta agggaaaaga gattctcttt tgttcgaaga gaggtggcag
      721 gtaatttctt tatttccttc aaagcctttt ctgtgtaaga ggccgctaac ttcctagctt
      781 cttccacgcc tcctgtatgt tcaacgattt tgcgtacggc gtcgacatct tcttctgtca
      841 ttgccgcttt cttctctaaa taaggtagta gctttggttt gtttttttgc aaagagtaga
      901 tcaacggtaa agaatagacc ccttgacgca tgtcttctag tacaggtttg ccgatttcct
      961 ggctctcttt tgtataatct aaaatatcat cgataatctg aaaggccatc ccgatagaaa
     1021 gtccgatatc tcctgctttt tttgcgaagc gctcgcttgt tccactttca aaagcgccaa
     1081 cagaacaact taattggaac agttcagctg tcttacctga aatattttcc aaatattctt
     1141 ttacagaaag ttcataatta tagcgatcat ccatctgccc taattcgcca ttcaatactt
     1201 tttccatact gcgagaattc aattggagac ttttcaagga agtggagtaa tcagacaata
     1261 gtttaaaaca gcagacaaat aaatagtctc ctgcatagac agaaacgaca ttaccaaact
     1321 gactacggat attaggctga ccacgtcgca gatccgcttc atcaacgata tcatcatgga
     1381 tcagtgtggc cgtatggagc atttcgatag aagctgccaa agcgatggct ttgtctcgat
     1441 cttgctctgg tccaaattgt gagaacaata gctgataggc aggacgcaac agctttccgc
     1501 cggcatggat cgtttctttg atggcttgtt cgacaggttt gtttttcagg cggacagttt
     1561 cttccatccg ttttagtgtt tctgtcaatt ctttacttaa agcaggatag ttttcccaca
     1621 ttggatgtag cttcataaaa aaactccttg tgtgacgatt attttttggt aaacattggg
     1681 ctccattttt gtttggttcc ctgctcataa tctttttgga atcgttgaag tgtctgcaca
     1741 tgtcgtaaaa gataattcgc tgcgatcccg attgcaatcc ctgataaaat ccctaaaact
     1801 gaaaggactg gcaagtacaa catgactgtc catgattgtg caatgaaaga agccatcaaa
     1861 agctgtccga cattatgcat gaaaccgccg gccgcactaa ttccgatgat actgacacgt
     1921 tttggtccta attgcttgac caataacatt ccaaaataac taagcaaagc accactcata
     1981 ctataaagga atgtggaaat cgttccgcct agcaaagtag tcaggaatag tcgtagccaa
     2041 agtagtaaga agctgtcttg ttttttcatg gtaaaaatgg caacgatcgt gattagattg
     2101 gctaagccta gttttgcacc aggcgcaaaa gaaaaaggat aagggatcat attttccaat
     2161 aaaccaatga tcactccttg tgcaacaagt agcgaaatat aaatcatttt ttgtaattta
     2221 ctcatggtgt gtgaaggtct aataaatcag actgtcttcg tcacctccat ctgttgaacg
     2281 gacttcgatc actaatttat gtggcaaaca gacgatggtt tcgccatttt tcgttgccca
     2341 gcctcgacgt acgcagatct ggtcatcgca atctgcttct tttatccgta ctcgatcgcc
     2401 atctatctcg atcaagttat aatctccgtg ttcatctttg taagtatatg tgttgctctc
     2461 ttctccagcc atcaaaggga atgttttgat ttctgtgcca tccacacgca gtaccgcttc
     2521 tttttctgct gttgcggtgt tttgctgaag accaaaaatc atgactggta aaaaagaaag
     2581 aacagtcaaa agcaaaataa taaaaacatc ccaaggtttg agcagacttt tttcagcaaa
     2641 ttctttaagg ctcatttttg ttctcctttt tccagattaa ctcacccaat tttagcataa
     2701 aaacaagagg ttgtgacacc tgtgtcttgc tttgagtaat aagaacgaag aatagaaaac
     2761 agctttccat gttttctaat tctttgggct tattaccgag aagcagcagg tggaacaccg
     2821 tttataacaa gaggttgtga cagaagtggg caacttcaag aaataagaag gaatttacga
     2881 aaattacttt tcaagttttt gtgaaatttc ggcttatttt tcgaagaagc tacttctgga
     2941 acaccgttta taacaagagg ttgtaacaga ggttgtgaca cctgtgtctt gctcatggag
     3001 gcttatctcg ggcatcttat tcctttaatt ttacataaaa aggaggctgt gacggtttgt
     3061 ctcagcccct ttctattgaa atcttgcatt caaataacgt tctttatcta tttatttctt
     3121 gccgtactgg gaacttggtc taccgtacca ccaattacct agtgtacgtt gtagccatgg
     3181 aattacccag cgatccaacc caatcgcacg tccggaaccg ttcatcaatg cgaaagcaac
     3241 aaaaatgaac caaatgttta cccagtaaaa catgcctgat aagcagaacg tgatcaccaa
     3301 tacaatcgtt gtcgcactgc atagccatgt gaataatcca gcaatcaatg ctaatgccaa
     3361 ggcaatttca aagaatacca tgaatttttg gaagaacatt gctacatcat tgtttggcat
     3421 gatcacttgc atgatctttg tgaaccagtc tggtgacttc tcaatcacag ccattggttc
     3481 ttcaccgtat gcataactca aaccaaaatg tgcagcttga gtcgctgctt ctccggcact
     3541 tgcccctgct ccgctggcag ctgtggttgc atcaccagca gcagaagcac cactggcaac
     3601 atctgttaca ttgtattccc atgtccaagg gaacacactg tttccagtga accatgatcc
     3661 ttcaccaaac caagtacttg gtttgaacac ttcaccattc ccaatgattt ttttggaagc
     3721 ttcaacgaac caaactaaac catagaaaat acgaagtggc acactccata agacattgcc
     3781 gtaacgagaa gaatgtcctc gagtcacgtt gcgatcatct ttgatatgga aaaactcatg
     3841 cattaaatat tggaacatat aataaccaga acgaatatca aagaagtatt tcaaattcac
     3901 gatatgtttc attacgatag ctaaaaatcc gcttaaatgg atcttatcaa ataggttagc
     3961 taccccccat ttggcaccaa tagaaaccat aaatccttga tagtttcctt taaatttatg
     4021 cttttctccg cctttgatcg aagccacgat attcgctgcg gctgtgtgtc ctgtttgttc
     4081 agcagcttga acgatctgcg gtgtcggtgt tcctgggaat tcttcataaa agactaaatc
     4141 accaatgata tagatgtttt tatcttcgta gccttttgcc tgcatatatt cattggcgat
     4201 caaccgctgt ccgcgtgctg attctaatcc aaagtcagca gcgtcagaag ttcctttgac
     4261 accagctgtc caaatcagtg tgtgagtcgg aatgttgcgt ccgtctttca atttgatatg
     4321 atcagcagcc acttctacga ttggtgcatt caataataat tccacgttgt gcttacgcaa
     4381 atagcgttca gcttttgcag catcatttcg atccaacata ttcaagatcg tcggcattgc
     4441 ctctacgacc atcagtgtga tttcgtttgg atctaattta taatctttgg ctaggcgatt
     4501 tttccagtcg atcagttccc caatcatttc aataccggta aatccagaac cacagacaac
     4561 gaaagtcagc atggctttac gcagttcatc atctggttcc aatgcagctt ttgctactgt
     4621 cttctcaata tgttcccgaa tccttacaga atcttcaaat gaccaaaggg tgaatccgtg
     4681 tgctttgaca ccaggtgtac caaagtcatt cggctctccg cccattccaa ggatcagctg
     4741 atcaaaagga taggaaccta atttggtctt gacgattttt cgttctttat cgataccgat
     4801 tacagtgtct gtgacaagtt gtacattctt ttgacgagca aacaaatgct gcagatcgta
     4861 ttggattgct tctggttcta cacgtccgcc agctacttca tgcaactcgg tcatcatagt
     4921 atggtacgaa tgacgatcga tcagagtaat tgctacatct tcttttttca gtttctttgc
     4981 caagtatttt gtagctgaaa caccggcata tcctgctcct acaacgacaa tattttgctt
     5041 tgccattgat catccgctcc ttatagacta tctatataat gaatatatga taattctttt
     5101 agtttgatac ttattacaca atctccatat attatataga tgttctgttc ttttgtctaa
     5161 ctccttttgg atttttttca aattttaaaa taaagcgttt tttcacgaaa tttgctgaaa
     5221 gaaaacgttt gaaatattac atgggttatt tatcaaaaat agttgactta taggctaaaa
     5281 agattagaat gtataatgaa tcacaaagaa aaattgtgga ctagaaatgg aatggtgggg
     5341 tattaaaatg aagaaaaaac gttttgtaac tggatttgcc gtattagcat tttcagctct
     5401 agtgttaggc gcttgcggcg cagatgacaa cggaagctca aactcttctt ctgaatcatc
     5461 tacagcacaa tcttcgactg caaaaagcac aacagaatca tctgcaaaag ttgtagctgg
     5521 cggagatttg caagacggca catataaatt agaagaaaaa aattattcaa atggttaccg
     5581 tgcagtcttt gaaatggttg taaaagacgg caaaatcact gaatcaaaat atgataacgt
     5641 caatgaaaac ggcgaatcaa aaacaaaaga tgcagaatac aacaaaaaca tggaagcaaa
     5701 atctggcaca aacccagaaa aatacattcc tgagttgaat gaccaattct taaaagcaca
     5761 aagcgcaagc ggtgtggaag tcgtaactgg agctactcac tcatctgaaa gcttccaaaa
     5821 ctacgcacaa caattgatcc aagctgctca agctggtaac acagatacaa tcgaaatcga
     5881 caatggtgct gatttgaaag acggcactta caagcttgaa gaaaagaact actctaacgg
     5941 ctaccgtgtg caattcgaaa tgacagttgc tggcggcaaa gtaactgaat caaactttga
     6001 ttatatcgac aaagacggta aatcaaaaca agatgataca gaatataatg aaaatatgaa
     6061 agcaaaaagc ggtacagaac caaaaactta catccctact ctgaacgacg aattcgtcaa
     6121 agcaatgggc gaagaagatg gctcacctgc taatgtagaa gttgttacag gtgctacaca
     6181 cagctcacat tcattcatca tgtacgcaca acaattagtg aatgcagctg aaaaaggcga
     6241 cactcaaaca atcgaagtag ataatatcgt aacagaaaaa taatcacata atcatactaa
     6301 taaaagttgg agggtgggac gatagccaga ttaggcagtc gtctcacctt tcaaaatgaa
     6361 gagaggaaaa agatgcggaa aaaactacta ttttccttaa tcacactggg catctctttt
     6421 atggtgctaa ctggctgcag caactcagca aataaaacaa ccactgaaag ttcagcagct
     6481 accaagatat tgaaagatcc atattctgat gaacagttct tgttagggac ttacgttcgt
     6541 atccgtgtgt atgatgaagg caaagaatca gcattgaaac ctgccttcga tcgagtaaaa
     6601 gaacttggtg ataaaatcac gatcaatcaa aaaggttctg agatcgatga agtgaatgag
     6661 caagctggga tcaaaccagt aaaagtttct gatgacgtct acacgttagt caagcgggcc
     6721 tacgaatata gccaagattc tcaaggcgga ttcgatatgg cgattggtgc aatcacacaa
     6781 ttatggcgaa tcggttttga tgacgccaga aaaccttccc aagaagaaat cgatcaggca
     6841 ttgaaattag tggattatca taagatcgaa ctaaatgaca aagaaaaaac tgtttatcta
     6901 aaagaaaaag gaatgatcat cgatttaggt gcaatcgcca aaggttacat tacggacgaa
     6961 gtagtgaaag tcttgaaaaa acaaggagtg accactgcca tcgttgactt gggcggtaat
     7021 gtctatgtct taggccacag cccaagaggc gaaaaccaag actggacagt cggcatccaa
     7081 gatccgaaca tggctcgcgg atctgtttta ggttctatta aagaacggaa caaaacatta
     7141 gttacctctg gaatttacga gcgttattta gaagtagatg gcaaaaaata ccatcatttg
     7201 tttgatccaa aaacgggtta tccgttcgac aatgatatcg caagtgtcac gatcataaca
     7261 gataaatcaa ttgatggtga cgggttgtct acagcagtct tttcaatggg tgtgaaaaaa
     7321 ggactggaat acgtcgaaag cgaattgaat aacgggacgg aagcgatctt cgtgacaaaa
     7381 gacgataaag tatatgtgac cgatccaatc aaagacacct tcaaattatc ggaggactcc
     7441 cattacacga tgggtgaccg ttctgaacta aaataaggag tacgaaccat gacactaaaa
     7501 atctttttag aagtagttga aatacgaaca aaggtggcta gtgtatttcc ttttgcggta
     7561 ggggtattat tctctatcgc tttttttcat gagatacatt ggctaaacac ttttttattt
     7621 tttattggaa tgctagtttt tgatttagcg actaccgcta tcaataatta catggattat
     7681 gaaaaggctc attctgaagt atataagtat gaagaaaatg tcattggccg cagaaatcta
     7741 tctcctgtat tgattcgaaa catgatttta gctatgattg catttgtttt tgttatcggc
     7801 gttattctaa cgatcaatac gggttggctt ttacttttga tgggatttat ctgttgtttt
     7861 attggagtat tctatacatt cggaccgatt cctttatctc gaatgccttt aggggaaatt
     7921 ttcagtgggg tgactatggg ccttggaatt tttgccatgg tcgtttatgt caatacattc
     7981 ggttcagatg tctatgatct gacagtcaac ttttcatctg gacaatttga tttggtagga
     8041 aatctttggg ctatagcagc aatcgtatta gcttccttac ccttggtgtt tacgattgcc
     8101 aatatcatgt tggctaataa tttgcgggat cttgaccgtg atattgaaaa tcatcgctat
     8161 acactagttt tttatatcgg acgtcctgcg ggaacagtct tattccagct attgatgtat
     8221 gcttgctatt tcgtgatttt aatggggttg ttgagcggta tctatgaatg gccgatcttg
     8281 gtcaccttct tgaccttgcc aattgtgaag aagcatttgg atcaattcaa gcaaacgtta
     8341 ccccagccta tcagtttcag ctattccatc aaaaatatgg tcttattcaa tgccagttat
     8401 gtattggggc tattactaac aatcattatg caagccattt aacagcatga agaggttgtg
     8461 aaaaaactgc cctgcatcaa gtaataagaa cagccaaata aaaatagctc cttatatttt
     8521 tcgtttggtt gggcttatta ccgcagatgc aagcttttga acaccgttta tcaggaggtt
     8581 gtgaaaaagt cgcttagttt cgagtattaa gaaaaatttt gtgaaaatgg ctttccacat
     8641 ttttgcataa atttggctta ataccgagaa actggctttt gaacaccgtt tatcagaggt
     8701 tgtgaaaaag tcgcttagtt tcgagtatta agaaaaattt tgtgaaaatg gctttccaca
     8761 tttttgcata aatttggctt aataccgaga aactggcttt tgaacaccgt ttatcagagg
     8821 ttgtaaaatc agtgttttgt cctgagtatt agagaaacaa atggaaaaat agttcctcat
     8881 attttgccgt tttttgagct aataccgaag gacagctgat tgaacactat ttgttcggaa
     8941 aaagtgacta actatgacac aatttttttc acagtccctt ttttcacttg atttgattcg
     9001 taccagcgaa cttgacgaga actttcttgg tttggtaact atatggtatt cttttaacat
     9061 cctcgtttgc ttcttctaat ttatttatac aaagtcacac ttttttaaac atctgttctt
     9121 cgatacattt ctatttcttt taaacatcga taccaatatt ttgaacttaa gagtgcatac
     9181 caaatggatt catttactct tcgtcagtta cgaagataat caaaatctcc aacttcccta
     9241 cttatttcgt tttgagaatt atcgaagcaa tcttacataa ataactaaaa aacaaaaaac
     9301 cagaaaatca gtatactgat tttctggttt tacatggttt gttcaataaa aagctgttgg
     9361 aactgttaat attaaattat cgcatcgtta cgaattcttc cgctcctgtt ggatggatgg
     9421 ctactgtatt gtcaaagtct tctttagttg cacccatctt gatagccacg gcaaaacctt
     9481 gcagcatctc atcgacacca acaccaatag catgtaagcc gacgattctt tcttcttttc
     9541 cgacacagat caatttcatt tcgcattttt ggcgataatc atttaatgca aagtacattg
     9601 gggtaaagcg tgaacgataa actttcaatt cattttcgcc atatttttcc aatgcttctt
     9661 cttctgtcaa accaattgtt gcaattggtg gatgcgtaaa gacgactgtc ggaacaagtt
     9721 tatagtcaag ataagaatct ttctttccat taaataaacg ttctgataaa cgtctaccag
     9781 ctgcgattgc aacaggagtc agatctaatt taccgatcac atcaccaaca gcaaaaatat
     9841 gttcatccgt tgtattttgg tatttatcta ctttgataaa cccttttttg tccaattcca
     9901 catttgtatt ttccagacct aatttttcgg tattcggtac acgtccaccg gcaaaaagta
     9961 cacaatcacc agttaaggtt tcaccatttt caaatagcac cgtatattcg tcattgtttt
    10021 tagtaatttc tttagcaata tgatgtgcgt aagtttttat tccagcttct tggtacattt
    10081 ggatcaaatt gtccgaaagc attttatcaa acgttctaag tggtcgttct tttcgatatg
    10141 cccacatgac ttcactacct aaaccacgaa atacacctga aagttcagcc gcaatgtatc
    10201 cagcacctaa aacgattgct ctcttaggta actctgttaa ttcaaaaaat ccatttgaat
    10261 caattgcgta ttctccacca ggaatggtca ttttacttgc acggcctcca gtagcgatca
    10321 agattttagg agcacgatag gtttcaccgt ttacttcgat cgtttgacta tcgataaaag
    10381 tagcgtaacc ttttatagcc tcgacatgat tgctatctaa tcctctttga taagcaccgt
    10441 gtagaaaatc aatatatttt tctcgtcttt ctactagacc ggcgaaatca acatttttta
    10501 aatctgcttg gataccgtaa cttgaggcat ctcgttcaat tgtttccaaa atcgtacttg
    10561 cttgccacat aactttttta ggtacacaac cgacgttgac acatgttccg cccaattcat
    10621 tcgcttcaat cagcaaaact tttgcgccat gcatccctgc tctgtttgct gaagcaatac
    10681 cgccagagcc gccaccaatt acgatgtaat catatatttg cattttgttc ctccttattg
    10741 aagagatcaa tcaaaacctt tatttaacga tcctttttct acagaaaaca agtgtaacac
    10801 ttttcttgaa ttttgtatgc gaagatgctt aaaacaggga tatatcagct ttttccttat
    10861 ttacgttttc ggatcatatc tccaggtttc accggctgtg cgactggcat agttaaaatc
    10921 atcattggat ttggtgctcg gtcaatggat tcgccttctt cattatgcat aacttcaacg
    10981 gtttgactga aatgactgaa tcctggacca taaaattcga tttcatctcc tacagaaaac
    11041 aagtttctct gacgtatcgt agcaatctgt gttgcctcat cataagataa tacttcaccg
    11101 acaaatttat atactgggat tttacgacgt tcaccgaata attgttcgtt ttcagttggt
    11161 gtattgtagt aaaaacctgt agctaattct cgttgtgcta ctttccataa ctcgtcgatc
    11221 cattcttgct tgcagacata gttttcagga tcttccatat aactgtctac agccgcttta
    11281 tagacatttg acaccgtaga tacataatgg atcgatttca ttcttccttc gatcttgaag
    11341 ctgtctacgc cgttttcaat caattctgga atatgttcga tcattgacat atccactgca
    11401 ctcatcgaga attcttcttc cacttcgcct gtatcagtta aactgtttcg ttcttgacca
    11461 aaaggcatat cgaacaatcc atacttccag cgacaagatt gagaacatcc gccacggttt
    11521 gcatcccgca tcgacatatg gttggacaat gtgcatcgac cagaataaga gatacacatg
    11581 gcaccatgga taaatgcttc gatttcggta tccgtatttt tacgaatctc tgccacttcc
    11641 tccattgaaa cttcacgagc taaaacgaca cgttccaacc cttcttcttt ccagaattcc
    11701 aatgtctcaa aattagttgc tgaagcttga gtggataaat ggatcggcag acctggggct
    11761 tctgtcgcac aaatttcgat caaagctgga tcagaaacaa tcactgcaga aataccgaca
    11821 tcacgcaaac tgcggaaaaa ttcccctgct ccatcttcat ttccttcatg ggtgaccata
    11881 ttagcagcaa cgtatacctt cgcatcatgt tcttttgcaa aagcaactcc ttcagccatt
    11941 tcttcataag taaaattacc tgcacggctt cttaaaccat atgcattccc gccaatatat
    12001 actgcatctg ctccataatg gatcgcggtt tttaactttt ccagtgttcc tgctggcgct
    12061 aggatttctg gtcgtttcaa ttttcttttt actgtcattt ctttcatcat actccttatt
    12121 tgatagcaga aggatcaata taaaagaatc ctgtatctaa ttcacggttt tcaggatgca
    12181 atttactgat ttcgctagtc attttttccg ctttttcttg atcccagcta ccttctaaaa
    12241 tttgtttttt tgcttcggcg aatagtcgag tgatgtttac gaatttttcg cctggagtaa
    12301 ataatccgtc caatttccat gtacagtaat gatgctgata aagttcattc aattcattcg
    12361 agagattcag atcattgctg gcaaaaatat gtgtgccatg actatcttca taaatagaat
    12421 aatgtgtctc ttctttttta ggttccgaga taaaaagacc tctttcacga tctttttgtt
    12481 cgtcttgttt cgtatagtta tagtaattct gtagcagtgg acgtttggat tgatggatgc
    12541 atgtagcacc atacacaagg gtttctacag gaatatcgag tttttcttcc atcgccttca
    12601 tctcttcaaa aggaacttca cgagcaagta ctgctccaac tgcgcctttt ttcgcccaga
    12661 aattgatttg acgtgcgctc gttactaatg tttcagcatc ataaatatac ggtatacgca
    12721 attcaggatt ttttttcatc gtataaataa tacctgtatc accaactgtg atcacatcta
    12781 cgtttatttc ttttaaaaaa gccaaatatt caggtacatt tttcattttt tcaggatgaa
    12841 tgatcccatt tacagcaata ttcgcttttt taccatactt gtgtgctaat tctaccaatt
    12901 gtcgctgttc ttctcgtgta aatgaagcag gcagacgcaa tccaaattgc tcttcaccga
    12961 aatatagtgt atctgcacct gcagcaagca actgttctgc ttgttcaata gtttctactg
    13021 tggttatgag ttcgatcata attttctcct cctacaactt cataatagta gcatagctct
    13081 aaaaactttc caatacttct tctatttaaa gtcggatttt tgaaaattat ttcacaaaaa
    13141 atcaaaataa agttcgatat attctgtcca aatataaaaa gagattgtga caaaaatctt
    13201 gtcacaacct cttaatcaag tcttactatt ataaaaattc agctacacag gccaagtaac
    13261 tatagggaac ctactgtttc ctttttaggt ccgcgaacat tcaatgtgat cttacctttt
    13321 gaagcaccta ctgttacgtg gtcacctaaa cgaatttctc cgccaagcaa agcctcgctc
    13381 aatcgatctt caatttcttt ttgaagtgcg cgacggattg gacgtgcacc atattcagga
    13441 tcaaatccag ctttcccgat cacatcgatt gcagatggtg tgattttcac ttgaatatct
    13501 tgttctttca atcgtttgat aatcgctttg ctcatgattt ggacgattgt atggatttca
    13561 tctttactca atgaatggaa gacgacagtc tcatcgattc gattcaagaa ttcaggtcgg
    13621 aaagctttct ttaactcttc taagatacgt ttttgcatgg ctttgtgatc tttagtaaca
    13681 tcttggacat tgaatccgac atttttttct tctcgaattt gtgtcgctcc gatatttgaa
    13741 gtcataatca tgattgtatt tctaaagtcc acttttctac ctttagaatc tgttaaatga
    13801 ccatcatcca atacttgcag aagtaaattg aaaacgtctg gatgtgcttt ctccacttca
    13861 tctaagagaa tcactgaata tggtttttga cgaatttttt ctgtcaactg tccaccttca
    13921 tcatacccta cgtatcctgg aggagacccg attaatcggc ttgtactgta tttttccata
    13981 aattctgaca tatcaacacg gatcagggca tcttcacttc caaacatgac ttctgaaagt
    14041 gctttggcca attctgtttt tccgacacca gttggtccaa ggaacatgaa tgaaccaatt
    14101 ggacgatcag gatctttcaa tccgcttcgt gcacggcgga tcgcacgtga aactgctttg
    14161 acagcctcat cttgaccaac gacacgttca tgcagaagtc cttccagttc taacaagcgt
    14221 tcgctttctt ttttctccaa ctgctgtaga gggacaccag tccactccga tacaactgta
    14281 gcaacatctt cttctgttac acgatcagaa taaccttgct cctgttttgc ttcaattgca
    14341 gaaacttttt gcagcttttt acgtagtgct ttttcttgtc tgcgtaattg agcagcattt
    14401 tcaaagtctt gtttttggat cgctgcttcc ttttcttgta ctagttcatc gatttctagt
    14461 ttgatcacag ttgattttgt taagtgatcg gtttgatcca aacggacttt cgctgctgat
    14521 tcatcgatca aatcaattgc tttatcgggt agttgacgag aagtgatata acgaacagaa
    14581 agattgactg ctgctcgtac agcttcatct gtgatctcca ctccatggtg ctcttcatat
    14641 cttgtacgta atccttgaag aatcacttct gcttcttcag gagttggctc atctacttga
    14701 atgcgagcaa aacgtcgctc taatgcagaa tctttttcga tatatttttg atattcatct
    14761 agggtcgttg ctccgatcgt ttgtaattct cctcgagcta acgccggttt caagatattc
    14821 gaagcatcaa ttgctccttc tgctccacct gcaccaatta aggtatgcaa ttcatcaatg
    14881 aataagatta cttgaccatc attatagatt tcgtcgatga cctttttcat tcgatcttca
    14941 aattcaccgc gatatttcgt accagcaacc aaagatccca tatcaagcat catcaggcgc
    15001 ttttcttgca tgtcttctgg cacttcacct aaaatgattt tttgagctaa cccttcagca
    15061 atggctgttt tgcctacacc aggttcaccc accagtacag ggttattctt tgtccgtcgg
    15121 ctaagaatct ggataagccg tttcacttct ctcgaacgac caacaactgg gtccagcttg
    15181 ttttcttttg ctaatttcgt caaatcacgt gctaatgaat ctagcgtagg tgttccttgc
    15241 ggtgtttgcc gtttatcttg tacatttaca tttctacgac gattcattcc ttttccagca
    15301 gaatcaccag ctagccccat tttttgtttc agaacttgac gggcttttga aaggctgata
    15361 cctaagttga tcatgattcg agtagccatg atactttcat cttttaataa gctcatcaaa
    15421 atatgttctg ttccaacttt ttgagaacca gttttcttca cttcgctgct agctaaagca
    15481 aaaacttgtt tcattcttgg tgaatatgga agaaagactc ctttagggta agaacggata
    15541 ccaccataac caatcagatg ttcaatttct tcataaattt ccgtttcatt caaatccatt
    15601 tcacgtaata cttttccagc aattccattt tgctcgacca ctaaggctag taaaacatgt
    15661 tctgaactaa ctgattgatg tttcaaccgt tttgcttctt cttgtgcaat ttctaatact
    15721 gcttgggctc tttcagtaaa aagttcttcc atctaatctc acttcccatc ttcataactt
    15781 aaacgttcca gaaatgctcg gagaatccga gcacgtgtat gatcttcata ttcattgaaa
    15841 ttcaatgtgt tttttgcaat tgcactcaac atcaagtttc cttctttttt tgtaattatt
    15901 tggtcttcat aaagtttttg aataatagca aaagcatttt tctcactgat tgtatcatca
    15961 aataactgat ttatctgctc aagtaattgt tttttatctg aaatccttac ttttgcaatt
    16021 cgtatataac caccaccacc acgtttgctt tctactagat aaccacgttg gatggtaaaa
    16081 cgggtattaa tcacatagtt gatttgtgaa ggaacacagt taaagaggtc tgccatttca
    16141 atccttcgaa tctcgatcat ttcactattt tccagaattt tctttatata tgattcaatt
    16201 aaatccgagg tattctgatg tgccatctta ttcattccct ttgactaata ttgaccttaa
    16261 ttataacgaa tttgataata gaaagaaaga agaacgcttt ttgttaaata aatcctttag
    16321 aatcaacaaa aaaaaatacg gaatatacta ttccgtatcg acgcgcccaa gaggagtcga
    16381 acccctaacc ttttgatccg tagtcaaaca ctctatccag ttgagctatg ggcgcatatt
    16441 caatttaaaa aaattataaa tcatttgaaa acaaaaagca agataaaaaa aatcgggaag
    16501 acaggattcg aacctgcgac cccttggtcc caaaccaagt gctctaccaa gctgagctac
    16561 ttcccgttta aaaaataaaa aagac
//
LOCUS       DARPZF010000055        16511 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.058, whole genome shotgun sequence.
ACCESSION   DARPZF010000055 DARPZF010000000
VERSION     DARPZF010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.058"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            185..1183
                     /locus_tag="SLE65_002242"
     CDS             185..1183
                     /locus_tag="SLE65_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEI8449509.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1295..1804
                     /locus_tag="SLE65_002243"
     CDS             1295..1804
                     /locus_tag="SLE65_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HEI8449510.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1834..2493)
                     /locus_tag="SLE65_002244"
     CDS             complement(1834..2493)
                     /locus_tag="SLE65_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEI8449511.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2495..3259)
                     /locus_tag="SLE65_002245"
     CDS             complement(2495..3259)
                     /locus_tag="SLE65_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEI8449512.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3267..3944)
                     /locus_tag="SLE65_002246"
     CDS             complement(3267..3944)
                     /locus_tag="SLE65_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEI8449513.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3981..5366)
                     /locus_tag="SLE65_002247"
     CDS             complement(3981..5366)
                     /locus_tag="SLE65_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEI8449514.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5576..5660)
                     /gene="ffs"
                     /locus_tag="SLE65_002248"
     ncRNA           complement(5576..5660)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="SLE65_002248"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="SLE65_002249"
     CDS             complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="SLE65_002249"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HEI8449515.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6305..7162
                     /locus_tag="SLE65_002250"
     CDS             6305..7162
                     /locus_tag="SLE65_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8449516.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7243..7578)
                     /locus_tag="SLE65_002251"
     CDS             complement(7243..7578)
                     /locus_tag="SLE65_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449517.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7645..9015)
                     /locus_tag="SLE65_002252"
     CDS             complement(7645..9015)
                     /locus_tag="SLE65_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HEI8449518.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9093..9629)
                     /locus_tag="SLE65_002253"
     CDS             complement(9093..9629)
                     /locus_tag="SLE65_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEI8449519.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9938..11419
                     /locus_tag="SLE65_002254"
     CDS             9938..11419
                     /locus_tag="SLE65_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8449520.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(11522..12229)
                     /locus_tag="SLE65_002255"
     CDS             complement(11522..12229)
                     /locus_tag="SLE65_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HEI8449521.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(12308..12646)
                     /locus_tag="SLE65_002256"
     CDS             complement(12308..12646)
                     /locus_tag="SLE65_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEI8449522.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(12757..13719)
                     /locus_tag="SLE65_002257"
     CDS             complement(12757..13719)
                     /locus_tag="SLE65_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEI8449523.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLVSGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(13734..15065)
                     /locus_tag="SLE65_002258"
     CDS             complement(13734..15065)
                     /locus_tag="SLE65_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEI8449524.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(15073..15753)
                     /locus_tag="SLE65_002259"
     CDS             complement(15073..15753)
                     /locus_tag="SLE65_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HEI8449525.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(15972..16451)
                     /locus_tag="SLE65_002260"
     CDS             complement(15972..16451)
                     /locus_tag="SLE65_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEI8449526.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
BASE COUNT         4886 a         3441 c         2736 g         5448 t
ORIGIN      
        1 atttgcatac ttcataataa taataacata atacctaacc tctcgtaaaa atactagatt
       61 tgttttcttt tatttttcat cactagatac attctataac ttaccgtttc gatttcgaat
      121 tcaaacattt ttgagaagca ttctcaatta aattctgcta tagtgtgaaa agggaggaat
      181 ttttatggaa atctatgaca ttacaatcat cggtgcaggt cctgtaggga tgtttgccgc
      241 tttttacgca ggaatgcgcc aagctaaaac aaaaatcatt gacagtctac ctcaacttgg
      301 tggtcaatta gcaactttgt atcccgaaaa atatatttac gatattcctg ggtatccagc
      361 aataaaagca agtgaattaa tcgatcaatt agaaaaacaa ttaactactt ttaaccatac
      421 attccattta aaagaagaag ttctctcgct tactcgtgaa gacgaagtta tcgagattac
      481 tacaaataaa ggcatccatt attccaaagc agtcatttta gctttaggaa atggttcatt
      541 ccagccaaga aaattgaatt tagataatgc tgaatcattt gaaaaccacg gattggatta
      601 tttcgtgaat gatttgatga agtatgctgg aaaaaaagtc gctattgctg gaggtggtga
      661 ttctgctatc gattggacgt tgatgttaga gcctattgca agcgaagttt acttgattca
      721 tcgtcgcccg gaatttcgtg cgcacgaaca tagtgtatca cgcttgaaat cttcatctgt
      781 caacttgctt actccctatc tcatcgatgg attatcaggc aataatgggg aactgacaga
      841 tatccggtta aaaaaagtga aaagtgacga gacgattgat ttgatgattg attctctgat
      901 cgtcaattat ggattctctt ctaatttaga acatctttct tcttggggac ttgatagtac
      961 cagaaatgcc attactgtaa aatcagatat gtctacttct attccaggcg tttatgcagc
     1021 tggtgacatc tgtacctatg aaggaaaagt gaaactgatt gctactgggc tcggtgaagc
     1081 acctactgca gtgaacaacg ctttacacta tattaatcca aaggaacgaa ctcagcctgg
     1141 tcacagcaca agcttatacg ataaaaatct tcgtcctagt tgatttttta tatctctttg
     1201 catttcaagt taaacccgaa agcagtttct tgcatttttt tcatgttccg ttaacatgaa
     1261 atagagaaag aaaaaataaa gggggagcaa taatatggtc gtcaaaactg agactttaga
     1321 agaaaaggca agagaactat tgaaggaacg tggcgtaact gtagaagata tcgcacaact
     1381 tgtcatgttt ttacaaaaag actatatttc tgatttgact ttggcggatt gtactgaaag
     1441 tgtcaacagc gtgctaacaa agcgtgaagt acataacgcc attatcactg gaatccaatt
     1501 agatatatta gcagaaaaga aaaaattgat gagtccgttg caacatatta tcgaagatga
     1561 cgaaggcctt tacggtatcg atgagatcct agccttgtca atcgtgaatg tttacggtac
     1621 gatcggcttt acgaattatg gttatatcga caaggtgaaa cctggtattt taaaagaact
     1681 aaacagccac gatggcgttc atgtccatac cttcttagat gatatcgtcg gagcgatcgc
     1741 cgctgctgct gccagtcgat tagcacacaa agaaccagaa aaaagaagtc gccttactca
     1801 ataattcaac aaaaaaagaa agaaaacgtc tatttagacg agttctttct tttttgtttg
     1861 tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta ataatacaaa
     1921 aaataagata aagctatgca tgaaaaattc ttctggaagt acattgatga ttggatcagt
     1981 aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa ggataaaaaa
     2041 gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca tgccgatttg
     2101 aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga taaacaaaat
     2161 actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa ttttcacttc
     2221 ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga ggatggtttt
     2281 gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg tctcttgatc
     2341 taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata gtggtcgaaa
     2401 gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga acaatccagc
     2461 atattccatc cactgccatc tcgaattttt catattagaa gctccattca tccagtgatt
     2521 gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt gtaaaacctg
     2581 ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct gtttcatagt
     2641 tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg gctttatcca
     2701 taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct gtctctacaa
     2761 aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata ttcttatctg
     2821 ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta actacttttt
     2881 cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct tcttcccatg
     2941 taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca tagacttttt
     3001 tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg tagactgtct
     3061 ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt tctggtgact
     3121 tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat tcttccacaa
     3181 atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct aaatcaatta
     3241 aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt aaatgctgtt
     3301 tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga ggtttttgct
     3361 gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac tggtcctttt
     3421 ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg agttgtcttt
     3481 tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt gcaatattcg
     3541 taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg attatccgct
     3601 tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat ataatcatat
     3661 cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc ttcacgataa
     3721 tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc taacagtgtc
     3781 actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc caaagcagct
     3841 gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt agcaatttct
     3901 gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc accacctatc
     3961 ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta atctcctacc
     4021 acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc aatcgttgga
     4081 aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt attcagatcg
     4141 attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat tccattatag
     4201 accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata gttacgtaaa
     4261 aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc acccaatgtg
     4321 acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg attgacccgc
     4381 ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc cgtctttcct
     4441 cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa gatatctaga
     4501 ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg cccacgttct
     4561 agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc ggtagggatg
     4621 gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg gacttcaccg
     4681 acatactgcc cgtactttcc agcggctgct atttggacat cattgattac gtgaccttct
     4741 ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat ttcttttgca
     4801 atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc cacttgtgaa
     4861 cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc ccagccattc
     4921 ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt cgtctggtgt
     4981 ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt atttttatcg
     5041 aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt caactcttct
     5101 ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc aacttcattc
     5161 atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca acgatccaca
     5221 aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt ttctcgttta
     5281 cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg cagatcattc
     5341 gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct ttatcatacc
     5401 ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc tgccttgaag
     5461 caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag gaacattcat
     5521 ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg tttcattata
     5581 atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac acgcttcaca
     5641 agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt cattcgttga
     5701 ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt cagtcaaaat
     5761 catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt taaaccgctc
     5821 gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat acgcgccgaa
     5881 ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac aaggctctaa
     5941 ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac aggcttcctt
     6001 gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa ggttatatcc
     6061 tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt catgaagcat
     6121 ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt ctactgcatc
     6181 aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt tactttagca
     6241 tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac aagaggtgaa
     6301 caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa aaaactctcc
     6361 agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct ggatcaaaca
     6421 agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg taatcaacga
     6481 tcaaaaaaaa cacccatggt atcactatct ttttaaagat gcttcttgtg ttcaagaaaa
     6541 aagctttcgt ttgatccagc ttcacgtcga atcaaaagga gaattcttaa aaaaagaatg
     6601 gcaagatact attttggaat tatttcgcta ttctgctgat ttcttttttt atacagacac
     6661 agatgcgctc ttagtcgaac aaataaaccg tgattatctt gatgctactg aaatcaacgg
     6721 tatttttcta tctttagatg ctgattttga tacgacaacg tctgtattcg ttggttcttt
     6781 ccattcacct ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa tttttttaac
     6841 agagcaaaac aatctttata ctcacagccg tactttttct atgcaagatg tggctttaca
     6901 ttactataca aaagatactg taaaagatag taagttgatc aaaagttaca tagaactgat
     6961 caaacaaaat gaaatggaag tgatcattca agaattatgg aatgaattag gcaatgtcag
     7021 ctctgctgca aaaacactgt ttcttcatcg taatactcta aaatatcgaa tcgaaaaatt
     7081 tcaagaacag tctggtttca atctaaaaaa agccaacgat ttactgtttt gctatctttt
     7141 attgcttcat gaacataatt aaagatagat taaaggggtt gtgacaataa ttttgtcaca
     7201 accccttatt tcgaatgaat agtgttcaaa agctagtttc tcttacatca ttttttcaac
     7261 aaaatgcatt agccggtctt ttacatcttc ggttgaatct ttgattgaat caccataaac
     7321 agagattttc ttttttcctg atttgatttt tgctaacatt cccatcaaag aatccaagtc
     7381 actatctgaa agaccatcta cgatttctag taatttttca tttccatcaa atttgtcata
     7441 gacgaatttt tttactttcg tccgagtagt catatgatgg atcttttcca ttacttttcc
     7501 cgatacaacg actgctgtcg ctacactggc agcggctgct acgcttaatc cgattgttac
     7561 ttttgttgat gttttcataa gtatcagctc ctttttatct atctccatca tagcatagac
     7621 aaaaaaataa acgaactaat ccactcagtg aaatctcaat cctttaggga aaaagttctt
     7681 tactgttcct tttacttgtt tcccaaatcc gacaggtatc ttatctaata ctagcaaaac
     7741 ccatccttga ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt gccattcctt
     7801 ttgagtgatc ggcaagcaag gtatattctc tatctttttt gtagcaagcg ctaatgcata
     7861 gctaggttca aatcgattct ttttgaaatc tcctaaatgc aaacctgtac gtacgacttt
     7921 taaaccatcg agagaagggg ctaactcagg aacttcccaa agatggtcgt tgaacactaa
     7981 aagtcttcca gtagcttcat aatgaaaatc atttgaaaac tccgtccaga gtttttcctg
     8041 ctcttttgtc atttgcactt tacttttttt tcgtgtcttc ttttctttat gcatctgatt
     8101 ttgtccatga aaagtcagct ttgcaacaaa atgtccttca ccctgatctt tatgaggcca
     8161 tatacgtatt gttttttcca aaccagctac gcttccccat tcagaacgtc ctgaactaac
     8221 ggattgagtc aaaggaatct cctcaatcgt tactggataa ttttctacaa gccagctaat
     8281 gatctcttca ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt gtcctttatt
     8341 ttttagcatt tttattgctg aagacaaaat ctcttgctga cgtttttgac agtatagcgg
     8401 agattcttct gtccactctt ttattgcatt tggatctttt cggaacattc cttctcctga
     8461 acaaggagca tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga caagttctgc
     8521 gggtgcatga tttgtcacta ttgcgttcga aactccccat cgttctatat tttctgataa
     8581 aatcttcgca cgtttcggaa agatctcatt cgtcactaat aaccctttcc ccttcatttg
     8641 agcagctaat tgggttgatt taccaccggg agccgcacac aaatccaaaa ctttttcacc
     8701 gggttttgct gcagcagctg ttccaacgat cattgcactt ggttcttggc tatattcata
     8761 cccagcttga tggaggaaag actttccatt gacagtgcca agaaatccct cattgctgta
     8821 gggagcgggt tgtaattctt cgctatggta agtttggacc atgtccaatc ctgccggttt
     8881 tagtggattc caccgaaatc cttttttcac gcttccttgt tcaagcgcag aaaaaaaatc
     8941 ggatgcttct tcgcctaaaa gaagacgata ttttttgata aattgctgtg gtaacgttgt
     9001 cgcttcctcc ttcattccaa tgtttcgtta gacattttac aatctttttt acgaaaaata
     9061 aaggtggctg atctactttt tcatgttgct gcctaaggtg actgttcctt taagatattt
     9121 tccaagtatt catccgtcac ctcgttttta tcccaaacag cgttcatcat ttcaagaaaa
     9181 tcttgagaag aatcatctga gcgcaaactt cccaatgcat taagccatac caattcaagc
     9241 gacttttctt ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg ccgcttaaat
     9301 agcgaatcca tgtctaaatc agattttgca atgatttcac gaatactttc atggatagaa
     9361 aaaaaatctt tcaataagta gacaatgctt aaaacatcat cggaactgca ttcagctaag
     9421 tagttttcaa aataaacagt gatttcttct aatatcttct cttttaaccc gctgattgat
     9481 ttgaaatgtg tataaatcgg gtatgtagaa caaccgcaga actctgctaa ctctcttgca
     9541 gtaattgact tcattccata ttcttccacg tataccatac ttttgaacag caaatattct
     9601 ttactataat ttgttactct ccccatcatt cttacctccg tctcttttca tctacccata
     9661 aataaataac ataaataatt ctaaaaatat tattgataat tatcaaaaca tatttagtta
     9721 tatccattaa aaatcaattt ttccgcctta aaaacaagaa tatcttgaca aaatacccta
     9781 ggaaataaac aatagaataa acaaggtaac aaaaaaatta aataacgtta tataaaaaag
     9841 aaggcgacac tctgtgagaa taacacagac tgaaatgact ttccactcac agtttttgtc
     9901 taactatata caaaaacaga ataaaaagga ggtatttatg ctaattgaag caagaaaaaa
     9961 agagttactt gttctacaaa tggtcattca aaaaaataat tgttctttac aagaattatc
    10021 caatgactta catattccaa aacggacaat caaagaactg atccgaaaaa taaatgtatc
    10081 actcaagcaa tttttattga ttgatgaatt tatttattct aatcataaag gagagatcca
    10141 aaccaaagaa accgatcaaa ctaaaaagtt agctgttttt tctaagttaa aattatgcta
    10201 cctaaaagaa tccaatcgtt ttaactattt gatgttacta atcaattatc cacaaactgc
    10261 tgtaccaaaa aaatatttac ttgaacaact ttatatatcg ccctcctatc tcgaaaaact
    10321 gacaaaacag ctcaatcatt ccttaaaaaa attccattta cggatcctat ctgtaaaaaa
    10381 ttgctgtact cttgaaggaa atgagttatc tatccgtctc tatctttact tttttctttc
    10441 agatacattt ggaggtaacg attggccatt ttcctcactt gaattaaatg cactaaaaat
    10501 gaacagtaca gatgagcaaa tagaaaaaat ttcaaaacaa gaaaaaaata tctacttgct
    10561 gttaacttta ttcatattac gaaacaaaca acaggcatat tttccaaaaa cttcttctga
    10621 aatcactgaa ttgatggact tattgcagca tacacatgat tattcagaat actttacttc
    10681 tttttcagtg agtcgccctt gtgaagagac agaaacagag agagcctact ttaattattt
    10741 tttctattgt ttttttccaa atcaaatctc ttttcgacaa aaacaggaga ttggtttttt
    10801 attttccaca agcaaaaacc ttatttgtcg acaagtcggt caattgatga cttacttaac
    10861 tcaacagttt cctctcaacc atttagaaaa taaaatacca atttattttt attttcttgt
    10921 gttggcagtt gtttttttcg aactgttggg tgaatccagc agtagttttt ctacactttg
    10981 ctttccagaa gccacgtcca atcattctag ttcttttata caggaaaaga aattaagaga
    11041 aaaaatcgat acaatttttt caaaaaatgg ggaaagaaac caaatcagtc aataccttag
    11101 tcaattgatc caacacttac tacaaacaga aacgaaagag cagttactca tccatttgca
    11161 gataaccaaa cagtttacag gaaattatca tcttcaaagc catttgcagc agttatttcg
    11221 caaagatgct gttaaaatta ccgcatattc agaacatgct gatttgatca ttacagatca
    11281 gcatgagaaa atttcagatg aaacggagac tttctatctg gatacaacgc acaatacagt
    11341 gttatttggc aagttaataa aagcggttca tgaactgtat atgaaaaaag gttatgagaa
    11401 caaaacaaag aggatgtgac aaaattcttg tcacatcctc ttattccaaa taaatggtat
    11461 tcaatcagct aactctcggt attagctcag atcaaagcgc tgatttcaca acttctttat
    11521 tttaatctct tcggttgccg ccgaacaata agatcaagcg caacagctgc aggaatgtcg
    11581 aaagcgctgc tgcaacataa gtcagtgctg ctgcaaataa tacgtgtctt gccatcggta
    11641 cttcttcttc cgtcagtagt ccgccttcac tcaaaatttg gattgctcgc cgagacgcgt
    11701 taaattcgac tggtaatgtc accaattgga aaagtaatgc taaagaaaaa gcgaaaatcc
    11761 cgatattgat taacgtagag ttccagctaa gcaatacacc taccataatc aaggggaacg
    11821 aaatcatcga accaaagtta gctgctggaa caagtgctgc acgaatcttc aatgggacat
    11881 aacccgaagc atcttgtacc gcatgtccgc attcatgagc tgctacacct atcgcagcaa
    11941 ctgaagtaga ctgtgcagtt gcttgagaca aactcaacat cttattacct gaattgtagt
    12001 tatctgtgag atctccggca atttgttgaa caccgacatt atttatctgt tgactttgta
    12061 atatatattg tgctgcttgt gtaccagtca cattgttttt gcttctcact tgatcgtatt
    12121 ttcggaaagt actattgacg tacgctgacg caattccgga aataactaat ccaagaatga
    12181 ccaaaagaaa tgtcggatct aaaaaaccat acattccata accatacatt ttcgtttcac
    12241 tccttttcgt ttactttatt ttatcattag tagtaggaaa agaatgtgaa aagaccttga
    12301 atattcttta attctttttc acaaattccg atttcagttt catcggtcca aatccttcta
    12361 ccttgcaatc gatattatga tcgccttcta ctaaacggat gttcttgact tttgttcctt
    12421 gtttaatggc acctgacgca ccttttactt tcaagtcttt aatcactgtc acgctatcgc
    12481 cctctaacag acggtttcca tttgcatcta ataccactaa tccgtcttct atgacagttt
    12541 cttgttcttc tttgttccat tcgttcccgc attctgggca aatcaacaag cctcgatctt
    12601 catatgtgta ctctgagcca cattctgggc aatttggtaa tgtcatcttc tttctccttt
    12661 aaaatcttta gtgagcacta ttgtaacgga aaaagaagat cttgaaaaga tacatttgtg
    12721 atttttacta caaaaggcac gttttcgaac gaagtatcat tctgtttttc tgctcttata
    12781 cgattggcat atatcttgga tctctttata gatttcctct acttctgcta aatcttttgc
    12841 attcgcacca cttactaatg gatggcctcc tccatgatgg cgtttagcca attcattgat
    12901 gatcggcccc ttagaacgta aacgtacgcg gtaataccct gaaggctgct gaacaaaaat
    12961 cccccaagcc agcacttcgt caatcactcc aggaagtgaa acgatcgaag ctgtctctga
    13021 atcatcgatt ccatatttat caagaatttc ttgcggaagg attattcttc ctgcaccatt
    13081 ttcatccacc tggatatttt gataaagata accggaaagt ttagcgactt tcatcggcat
    13141 ttgttcaatc tctctgttca aagcacttgc atcaaatgga taatttctca atatcgaagc
    13201 aatctctaat gtacgggacg tcgtggaggg atacaaaaag cgccctgtat ctccgacgat
    13261 tcctgcataa agtaaccgtg cagccttaac gttcatcttt aaagattcag gaaacatcaa
    13321 agcaaattct gcaatcatct cactacagct acttgctttt gtatttaccc acacaagatc
    13381 tccataaggg tcatcattgg gatgatggtc gattttgatc agtttttctg ccaactgata
    13441 tctttgatca ctgattctgg gtgaattagc tgtatcagtc acgatgacta gcgctccttg
    13501 gtagaagaca tcttcaactt cttgcatttc tgctaaaaag cgaagccctt caatcgtttc
    13561 acctacttga cgtatttctt tttctgggaa actttcccgt aatagttcgg ctaatcctac
    13621 ttgtgatcct aatgcatcag gatcagggcg caaatgcctg tggataatga ttttatcgta
    13681 tttttttatt gtatctacta tttcttgctg tactgtcatt tcactcctgc tttctaagaa
    13741 cgttccatta cttgacaaac aacgattgct ttggaaacga tggtgttttc aataaacact
    13801 tcgatatcca gtttagcgga acgtctgccg atttccaata cacgtggacg aatgtctaat
    13861 tcgctttcca attggatcag ccgcaaataa tgtaggttca cttgttcaat caagatattt
    13921 cgtttttggt tcatcaccat tgttttttgt gcgacatcag aaatgatttc gctaagtacg
    13981 ccaaaagaaa tggttccaac gccattgacc atttgtggtg ctactacgaa tttgaactta
    14041 gggttttcca aacgatttcc ttcacggtca gtatcaatcg tatggatatt tccagatatc
    14101 tgatccgaaa tcgtatctgc aatctgcggt tgtcgctgga caagctgcat cgctttcatt
    14161 acatcttgcc gggtaatcaa gccttccaat gtcaagtcat cggaaacgac cggcatgact
    14221 tctagcccat cccagatcat ttgatggcta acagaggcaa tactcattgt tttctttaca
    14281 ctgattggtt ctttcgtcat cacccgatcg atgatctggt ttggcgattt ccctaaaaca
    14341 tcttttgccg taacaatccc catcaaacga tgatggcggt tgacgactgg aaaacgcgaa
    14401 tgctgcgttt cttctgacaa acgctgataa tcagaaatcg tatctgtctg ctgcaaataa
    14461 tgagtctttt cagctggcat atagatatca ctgacaagca tgatatcttt tttgatcaat
    14521 tggtcgctta acgctcggtt gatcatggtt gcgactgtaa atgtatcata agaggtgcgt
    14581 aagatcggca tttcaagatc atcagctagc tttgcaatct cagcagtcgt attgaatcct
    14641 cctgtgatca atactgcggc gccatcttcc aatgctaatt tttggacttc cgcccggttg
    14701 ccgacgatca ttagtgatcc tggcgtaata tagcgttcca tggcatgttt agtcatcgcg
    14761 ccgatgacga atttattcaa gaccttgtct aatcctgccg ccccgcctaa aacgtcccct
    14821 tcaatgatcc tgacgacctc gccaaatgtc aaacgttcaa tatgtttttt taatttgcgt
    14881 tcgatacgga tggtccctac tcgttgaatt gttgaaacta gtccgacatt ttctgcatct
    14941 ttgattgcac ggtacgctgt tccttcactg acattcaatt cttttgcgat gcttcttaca
    15001 gaaattcgat tgccaacagg taaactttca atatattcta aaatcaaatc atgttttgtc
    15061 gccattttct gcctacactt ccagcgtttc cgagacgctc attatttttc cttcactatc
    15121 ttccagtaac tctacaaaag attcgggatc ttgttcaatg acagggaaag tattgtaatg
    15181 gattggaact actttcttgg cacgaattgt ttgcgcagcc tttgctgcat cttctggccc
    15241 catcgtatag ttatcgccaa tcggcaagaa agcgacatca atatcgaatt cttctgcaag
    15301 caatcctaga tcactgaaat aagcagtatc ccctgcatga taaatcgttt ttccttctgc
    15361 ttgaataata attccgctag gctcgcccat atactgaacg ataccgtcta cttcatagct
    15421 tgaactatgc tgtgcatgta cgaattttac cacgccgaat ggaaacgcat gttttccacc
    15481 gatattcata ccgaatgaat ctactcctct gctgttcgca taatcagcaa tctcaacaat
    15541 actgataatt gtggcttgat tttcttttgc aataggaatc atatctccta tgtggtcact
    15601 atgaccatga gtaatcagca accaatctgt ctttacttct tctgcagtta agtctgtcaa
    15661 tggatttcct gtaataaacg ggtcaatcat cacgcgttgg ccattttcca tttcaattgt
    15721 taaacaggaa tgtccatgat acgtaatttt catattttac acctcgcgtt ttctctgtat
    15781 cttttttatt aaaaacgatt tcatcacttg cacatcaatg aaaaaatata gctgctaaat
    15841 atattttcat tggattgata gtacagtatg tacaaagcaa ttgtaacaga taatacagga
    15901 tgcaccaagt accaagcaga tataatctca agtttgaggt ctctgctctg cttagcttct
    15961 cttctcgtcc cttaactaat taaatcagcg taaataggat ggacgatctt ttctaaatcg
    16021 gctactttta tccgaaggct tctcccgatt tcaccgcttg acacaattac ttcttctttt
    16081 tcttttaaag aactgtctgc taaaaaacaa taatcaggat gtgcgagttt tattccaata
    16141 ggggtgtttg ctccgtgggg atatcctgta tgcattaata caaaatccat tccaggaaaa
    16201 ccaactttac gatctttcgt cacttgtctc gtttttttgt aatctaagtg atcgttcaaa
    16261 ggaatcaatg cgatgatcac cccagttttg tttcctttca ctacgagagt tttacatatc
    16321 aaagctggat caatccctct tttttgtagt tcttctgtga aagattcttc taccacatga
    16381 ctaaaatcaa gtggttgata gctgatcttt tgttcttcta aataacgttc gacttttgtt
    16441 tgactcatca ttgattcact ccctttattc tatcgtttat tataaagcga gggatgctgt
    16501 attcaaaaat t
//
LOCUS       DARPZF010000056        16464 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.059, whole genome shotgun sequence.
ACCESSION   DARPZF010000056 DARPZF010000000
VERSION     DARPZF010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.059"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(78..353)
                     /locus_tag="SLE65_002261"
     CDS             complement(78..353)
                     /locus_tag="SLE65_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEI8449527.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(596..1906)
                     /gene="der"
                     /locus_tag="SLE65_002262"
     CDS             complement(596..1906)
                     /gene="der"
                     /locus_tag="SLE65_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEI8449528.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(2088..3317)
                     /gene="rpsA"
                     /locus_tag="SLE65_002263"
     CDS             complement(2088..3317)
                     /gene="rpsA"
                     /locus_tag="SLE65_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEI8449529.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(3452..4132)
                     /locus_tag="SLE65_002264"
     CDS             complement(3452..4132)
                     /locus_tag="SLE65_002264"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEI8449530.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(4181..4816)
                     /locus_tag="SLE65_002265"
     CDS             complement(4181..4816)
                     /locus_tag="SLE65_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEI8449531.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(4882..6285)
                     /locus_tag="SLE65_002266"
     CDS             complement(4882..6285)
                     /locus_tag="SLE65_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HEI8449532.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(6272..7303)
                     /locus_tag="SLE65_002267"
     CDS             complement(6272..7303)
                     /locus_tag="SLE65_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8449533.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            7334..7555
                     /locus_tag="SLE65_002268"
     CDS             7334..7555
                     /locus_tag="SLE65_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEI8449534.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(7720..8457)
                     /locus_tag="SLE65_002269"
     CDS             complement(7720..8457)
                     /locus_tag="SLE65_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HEI8449535.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(8610..9950)
                     /locus_tag="SLE65_002270"
     CDS             complement(8610..9950)
                     /locus_tag="SLE65_002270"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HEI8449536.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(10187..11710)
                     /locus_tag="SLE65_002271"
     CDS             complement(10187..11710)
                     /locus_tag="SLE65_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEI8449537.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(12088..12699)
                     /locus_tag="SLE65_002272"
     CDS             complement(12088..12699)
                     /locus_tag="SLE65_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEI8449538.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(12822..12947)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(13029..13745)
                     /locus_tag="SLE65_002273"
     CDS             complement(13029..13745)
                     /locus_tag="SLE65_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEI8449539.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(13751..14320)
                     /gene="scpB"
                     /locus_tag="SLE65_002274"
     CDS             complement(13751..14320)
                     /gene="scpB"
                     /locus_tag="SLE65_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HEI8449540.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(14304..15101)
                     /locus_tag="SLE65_002275"
     CDS             complement(14304..15101)
                     /locus_tag="SLE65_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEI8449541.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFGTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(15071..15442)
                     /locus_tag="SLE65_002276"
     CDS             complement(15071..15442)
                     /locus_tag="SLE65_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEI8449542.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(15461..16348)
                     /gene="xerD"
                     /locus_tag="SLE65_002277"
     CDS             complement(15461..16348)
                     /gene="xerD"
                     /locus_tag="SLE65_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEI8449543.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT         4623 a         3567 c         2789 g         5485 t
ORIGIN      
        1 tatttattcc ttttctgcta ggaaataaaa agaaaagcac ttgtagccct agagccacaa
       61 gcgctttttc aactgtctta tttaacagcg tcttttaatg ctttacctgg tttgaatgca
      121 ggtactttgc tagctggaat ttcgatttct tcaccagttt gtgggttacg acctttgcga
      181 gctgcgcgtt cgcgaacttc aaagttacca aaaccgatta attgaacttt ttcgccgtta
      241 gctaaagcat cttgaatagt tgaaaataca gcatctactg ctgcagttgc atctttttta
      301 gttaaatcag tagctgaagc aactttttcg attaattctg ctttgtttgc catggataga
      361 ttcacctcct ccacaagaga tatgatagaa atatcattta gttaaaactt tctgagtggt
      421 ccagaagttt aaaaagaaat attgattaac ttcaatattc tgttatcacg atatcatatg
      481 aaccgcttaa tagcaaggtt tttaccaatt ttcacatgct ttttttagtc atagaaacgt
      541 aacaaacgaa actgtctttt tcttttgaaa aaaaaacgtc gatatggtaa aatgcctatt
      601 ttctcctacg agggataatt cggatggacg tcccttcaaa agtaaatgct tttctgattt
      661 gattttctaa gaaacgttca taagaaaaat gcatcaattc ctcttcattg acaaaaacga
      721 caaatgtagg tggtttgaca gcgacttgtg tagcataaaa aatcttcagg cgttttcctt
      781 tatctgttgg tgttggattg attgctacag catccataat gatatcattc aacacagccg
      841 aagagatacg aagattctgg ttcatactta cttgttcgat catttcaggc agacgttcca
      901 accgttgttt agtcactgca gaaacaaaaa cgattggagc gtaatcaaga taccggaatt
      961 catcacgaat ctcttgttcg aaatcacgca ttgtattggt ttctttcttt acaagatccc
     1021 atttattcac gacgataata attccacgac cagcttcatg ggcgtaaccc gctactcgct
     1081 tgtcttgttc ccgaatccct tcttcagcat tcagtaccat caaaacgata tcagaacggt
     1141 caatggcacg cattgcacgc atcacgctgt atttttcagt attttcgtat acttttccgc
     1201 gtttacgcat accagctgta tctatcatta agaatttctg accactttca gaaacgaagt
     1261 gggtgtcgat tgcgtctcgg gtcgttcctt caatatccga aacaattaca cgttcttctc
     1321 ctaaaatcgc attgatcaaa gaggatttac caacatttgg gcgaccaatc aaactaaact
     1381 taatcgtgtc gtcgtcctct tcttcagtct cttcagagaa atacttcact gcttcatcta
     1441 aaatatcacc aatccctagt ccatggcttc ctgaaacagg ataaggatcg cctagcccta
     1501 aggaataaaa ttcatagata tcgtttctca tttctggatt atctacttta ttgactgcta
     1561 aaatcactgg tttattactt ctgtataaaa ttttcgcaac catctcatct gcgtctgtca
     1621 cgccttcgcg tccgctgact acacaaatga ttacatctgc ttcttcaatc gcgatttctg
     1681 cttgatgctt gatctgatcc ataaaaggtt catcgccaag atcaattccg cctgtgtcga
     1741 tcacgctgaa ttctcgacct aaccattcac cttttgcata aatacgatca cgagttactc
     1801 caggagtatc ttcgacaatc gagatacgct caccagcgat gcggttaaaa atcgtagact
     1861 taccgacgtt cgggcggcca acgattgcaa ttgttggatt tgccatatta tttcctcctc
     1921 acaagtttcc aatctcactt agtttaacga atgcattgcc aactttcaag catagattgt
     1981 caattaaacg aagtattttt attccttatt gaaatactaa tcgcttttca aaagaaaaac
     2041 tgagacaaaa gcagctgctt tcatctcagt cacagataca aaatcaatta tttttcagaa
     2101 tcatcggttg ctttttcttc tacttcttct ttcaacgcat cacctaaaat gtctcccata
     2161 gtaaatccag tattttcttc tggtaattca taagactcaa cattttttgg ttcttcttct
     2221 gaagctggtt tttcttctaa agctttgata ctcaatgcaa tacgatgttc ttctggatgg
     2281 atctctaata ctttcacttt cacttcgtca ccttcatgaa gcacttcatg tggtgtcgca
     2341 atatgtttat gtgaaatttg agagatatgg actagccctt ctactccagg gaacacttca
     2401 acaaaggcac cgaagcttgt caaacgttta actgttccgt ctaatactgt gccaactgga
     2461 gcttttgtat cgatttctga ccaaggtcca ggctgtgtgt ctttgattga caaggaaaca
     2521 cgttcttgtt caggattgat agacaacact ttgacattta catcatcatt gacagccaat
     2581 acatcacttg gttttgctac atgactatgt gaaatctctg agacatggac tagaccgtca
     2641 attccgccta ggtcgacaaa tgcgccaaaa tcagtaagac gtgcaacacg tccactgaga
     2701 acatctccct catggatagt tgaaagaatt tcttttttct tttcttctct ttcgttttcc
     2761 actaccgctt tatgcgataa gatcaaacga ttttctgatg gttcgatttc gatgatttta
     2821 aagctcaatg ttttgccttt atagtctgaa aagtctgcaa caaaatgatc ttccaccatt
     2881 gatgcaggga caaaaccacg tacaccgacg tcaacgacta aaccgccttt gacaacattt
     2941 gtaacaggtg cttcgatgac cttgccctct tggaaatctc tttcgatatc ttcccaaact
     3001 tttttagcat ctaaacggcg ttttgaaagt aggtagctgc cgttttcttt atctttgccg
     3061 atcgtactga taacgactaa atctaataca tcaccgactt ttactacttc gctgatatct
     3121 tctaccggca aagttgataa ttcttttgcc ggaacgactc cttcaactcc agccccttcg
     3181 attccgacaa tcacttgttt gtcttcaatg actaaaactt cgcccttaac aacatcgcca
     3241 acttttactt cttgtacgct tttcattgcg tcttccattg actggttgtt ctcttgattt
     3301 tgatcaaatt ctgtcataac acttgtcctc ctaaccaaca ttctgccgta agtacggtac
     3361 tgtttttagt ttaattgatt attcaaaaaa aataaagcga tttcgttcgt tttccttgaa
     3421 aaaacaattg tttttcattt tttttcttaa tttaaaaaag aagataacct tttttcaaaa
     3481 caacagcttt tattgctgca acgacttctg gaatcgattt gccagtcgta tcgatacgaa
     3541 cagcatcctc tgcttgcttc agcggagaga cgtcccttgt tgaatcataa tggtctcttt
     3601 cctgtatctc tttcgtcagt gtttcaagat cagtcggaat tcctttttct tggttctctt
     3661 tgaaacgtct ttctgcacgc tcacttacgc ttgctactaa aaagattttc acttctgcat
     3721 tcggtaatac agctgtcccg atgtctcttc cgtccatgac aacgccaccg cgttccccta
     3781 tttttcgttg gacagcaact aattcttctc tgacttttcc atgtgcagag acttcagaaa
     3841 cagcttttgt gacatctggt tgacggattt ctaaagtcac atcttttgat gctatgaata
     3901 catgctgtcc atcttcttgt tgcgaaaaag agataggata ctttttgatc agcgaaacta
     3961 gcccttcttc atctgaaaaa gatacattgt tcgtaatagc taaataagtt actgcgcgat
     4021 acatggcacc ggtatctgta taaatataat tcaattcttt tgctaatatc ttggcaacgg
     4081 tacttttccc agatgaagca ggcccgtcga ttgcaatact gatttgtgtc atgatataac
     4141 tcctttttct cagaaaaaaa gccgcaaagc gcggctatta ttatttaatt cttaattctt
     4201 gaccagggta aagcataaag ttgtttggat ctaagccatt caattcaaac aattgatcag
     4261 tggtgatccc tgcacgctca gccacttgtt ttggaccttc gcctgcttga acagtcgttg
     4321 ttgaaccggc tgcagctgat gaagaaggtg ttgtttctgc tgcattgctg cttgaatccc
     4381 ctgcttgata agttgcctca cttgaggaag tcggtgttgt ctctgctgca atactgcttt
     4441 ctgacgttac acctgtatct tgagacacag tagattcttc cgcgattgta ctagattcta
     4501 ctgttgaagt ctcagttgac tcctcttttg ttgtacttgt agaactttct actactgatg
     4561 tcgaagtttc agaagaagtt gctgctgttg cattgttgct tgatccattt ctgatccaga
     4621 aataagcacc tgctggaata gcgatacata agaccagtaa aatcaaaaat agcgaaagaa
     4681 ataatgtatt tcctttcttt tgttgtctct gagaacttct tgatgaaact tcatcatctg
     4741 tatcgtagat tggttgttcc catggttctt gtgtttcgtt attttctgta gattgatgtc
     4801 tatcttttct gctcactgtt ttacctccta aactctatcg tgtgtattat accataggaa
     4861 aaagtgtctt gtcctaaaaa atcaatgttc catgtttttt ttaaataaat ttagtaaaat
     4921 cgtttcccaa tgaagttgtt cagtcttaga aaaaagcttc ctctttggca gaagttctgc
     4981 ttttgctcca tcaatatcac aacaattctg cggcttttcg gagagttttt cgccaaaata
     5041 agctaagatg aattttctgc ggcagttttc ttcattaata tagcgaagca tctgctgcag
     5101 gcggaattct ttttcttttt cctgacgttt gagccgttcc acccaatttt ctggtttttc
     5161 agactgctgg atcagctcca tccatttttt ttgcagctca tcaaagggag cttgctttgt
     5221 ggcatattcc aaataaagct caaaactttg tcgctgttct ctagaaagtt gattaaagaa
     5281 ataatggata cgttcatccc cactttgata aaaaagaatt gctgcacttt cttcctgatc
     5341 tctgcctgct cgaccgattt cttgtacata gttttctaga ctgtctggca aatcataatg
     5401 gaccacataa cggatatcag atttatcgat ccccatacca aatgcattcg tagcaatgag
     5461 aaactgcagc tgatttttta caaactgctg ttgaagttgt cttctttgag ctgcatcaag
     5521 accaccgtga tagtatccaa ctgtaaaacg ttccctgaat aaatgataca atcgttcgac
     5581 ttcttttttt gttgcacaat aaatgattgc cgctccttgt gctctttcca tgaagtgttc
     5641 aagttcttgt tctttttgct gcgttttccg aacaaaaagc gagatatttt gccgattgac
     5701 tgattgtctg atctcttttg gtggtcgatc aaatagtaca tgacgtatat ctcttgctac
     5761 taaatctgtt gctgtcgccg ttagtgccag tgtgaccggg tttcctaaaa gctttcggat
     5821 ttttcctaac tgttgatatt ctggacggaa atcaactccc cattgagaca cgcaatgagc
     5881 ctcatctact acatataacg caatattttg ttttttcaga tgctctaaaa gagaaggatt
     5941 agtcaacatt tcgggactca aaaacaaaaa tttatattgc gatagatgac ggaggacgta
     6001 tcttctttca gattgcgaaa gtaaactatt gaaagcagct actcgtttct cccctcgttt
     6061 ttgtaattgc gtcacttgat cttccattag agaaagcagc ggtgacacga tgatgaccag
     6121 accttccatt aaataccccg tcaattgata gcaaaggctt tttcccgttc ctgtaggcaa
     6181 aatagcgaga gtatcttctc catcaagcaa cgcctgaata atttcttctt ggccgggacg
     6241 aaatgaatca aatccaaaat atttttttaa ttcatttatt aacattctgt atcgcttcct
     6301 ttctcaatag atagatttga tacaaacgaa attctccata atctaattgt ccatctacat
     6361 tccattcgct aaagcgccac tctcgcacgg aatccttatt tggttccaaa cgttcgattg
     6421 tttctgcaga gagaatccac tcgtatggaa aatcatcaaa aaacaaggcc cactcaataa
     6481 gatgatctgt tactgttcct ctttttaaat gacggattgc catgatctgg tcaattgtct
     6541 gaccattcat aaacatctgc ttggtgatca tcatgctttg attgaaattt tgctgtaata
     6601 atgaatcgat caaagcgtgc caaagcgaat ctggccgttt ttcgatttgt gctaacaaaa
     6661 ggtggataca tctgctttgt tgcagataaa cctctgactc atcattgttt tttgccagct
     6721 gataaggaag cagccctgtt cgctcatttc cagataattg gttagctaaa aaatctgctg
     6781 cttcttctgg tatctccgaa aacagctgca ccaaactctc atacgcagta tcaatcaaaa
     6841 tttcacgtgg caattggctt tcactaagcc atttttttag ttggaaagta taaaaaggac
     6901 ttgtctctgc tggaagatag tcttgaatac ccgttgccag attagaaatt acttgaacag
     6961 caaatttaat gagccgccaa ctagtttccc ctgttctgcc atagcggtca aaacgcaaac
     7021 cagtatgttc tatttgatgt tcggacaaca tatcagcccc tgcaggcgtt agctttgctt
     7081 cattttcatt tatttcgatc caaccttgct gcgcaatttt ttgcaaaatt tgataaaact
     7141 tatcctgctt caattctgga aaactgttat ggataaacaa aagttcgtgg gtaaatccat
     7201 aaataagtac tgaagtcgtt cgttttccca caaggagttg gtaaagagaa ctaatccgca
     7261 gcttgtgtcc tgatgaaaat agcgataaaa taaaaacaat catattattc tccttaagtt
     7321 aggatggtta gaaatgtcac tactatgtaa acttgtacct gaacgctgta ttgcatgcgg
     7381 tctttgtcaa atcgaagcgc cagatatttt cgattatgat gaagaaggaa tcgttttatt
     7441 tgcccaagaa ccagaggctc atcaacagtt cgtgatgccg gaagaagaaa catatgtaaa
     7501 aaaagcgtat caaaaatgtc cagttcgagc gattttatta gaaaataaaa tataaatata
     7561 aacgaaactt taaaaacgta cactaagttc tctaaacttg aaaataagcc gggatctgtt
     7621 tctcttgttc cgtgaaatcc cgacttattt tgaaagattc atttgctatc tatagttaat
     7681 tgactagttt tttcacggac cctataggac ccatttatat tatttcaact ttttcagcca
     7741 gttttccaat gtattgacga tcacagtttg ctggtctgcg ttagaaattt ctgcctctcc
     7801 atctcctttt tgctcaccat agctgccaaa acctccatga tttccgccat tgattgatac
     7861 atactctgtt ctttccggta aatactgctt agcttcttga taagcttcct gattcaatac
     7921 tttatctttt gtcgccgtga tcgataaaac aggaacagct gattctgtca atgttccttt
     7981 tttgtcggga taacttgcca tgaagaatac cccttttaaa tgtttgtctg aatgattctt
     8041 attgacataa cgacttgcca ttacgccacc taatgaatgg ccaccgatca cataatcgga
     8101 atttggaaaa tcttctttga ccttatccgc tttgtttccg cccatcactg ctagatcaag
     8161 tggcattttg acaatagcga ctgaaaagcc gttttttgct aaatcttgcg cccaaatact
     8221 ataactttct ggctctacga gagcaccagg ataaaaaata agtaatggag actttccatg
     8281 attctttttc tctccttcaa aaaataagta atcttctttg ttttttcctt cttttaccaa
     8341 cacttgcgct tctgacgatg gttcgtacgt attttgctgt atatagtaat aaccggctcc
     8401 accgagtaat cctaaaatga tgactaagcc aattagtatt cgtctaaata ttttcacttt
     8461 ctcccacctt ttctatctga gtgacccctt tttcttaatc aagtatgatt ataccttaaa
     8521 aaaataagag agaaatgcaa actttccagc atcaaataaa aaaagacgga atatccattt
     8581 gaatatccgc cctttttgta tgtttatttt tatttagcac ataaacgata cacagcttct
     8641 gcataaattt ccattgcttt atacatacta cttaattccc atcgttcatt cgcctggtgc
     8701 ataaagtcag gagtatcagg gaacatcgca ccgaatgcca cacactggtt catcgtacga
     8761 gcaaaagtag cgccgcctga tacaaacggt tcagtcatgt ctccagtaat atcgcgatat
     8821 gtccccaata gatttttcac taactcactg tctagtggca cgtataatga atcaaggaag
     8881 tcaaattctt cataagtcaa cccatatttt tctgctgttt tagttaattt agctactaaa
     8941 tcatctttct tgaatgtaac agggattctc atatctacac cgatttttgt ttgttctggt
     9001 gtgatttcca aacttgcaaa gttcatcgtt agctcgccgg attgttcatc ttctgttttg
     9061 cccacgacag cttcaccagt tgcattttct tgaactaatt ttcctaagaa attgattggg
     9121 ccaaaatcaa atacttctga aagagcaatt gccagacgag aaatagcatt cactccttgt
     9181 gctgcatctt tcgcgtggat acttttacca agaacgacga tgccttcacc ttgttcttcg
     9241 aaatcgaatt cgtgtttttt caatgcttct tttacttcag aaagcttttc tccagagtaa
     9301 ggagctgcat caggaacaac attcaacgct cctccagctt ttacagaaaa ctcgttcgtt
     9361 cctggtcctg tcaagtaagc ttgcaataag cctttttctg cataaattaa aggaaattca
     9421 gcatctggcg caaatccttg cgtaattcct tcttcttttt cgttatattt ttctaaacaa
     9481 cgccataaat tttcttcatc tgtaccaaag ataaaacgaa tacgtgtctt gaattccacg
     9541 ccagcatcaa tcaaagcttt gacggcatac attgccgcaa tagaaggacc tttgtcatct
     9601 tgggatccgc gaccaactaa ccagccgtct tttatagttg gatcgaatgg ttttgtttcc
     9661 caattatttt cgtcccctgc tggaacaacg tccatatgac acaagatacc gaataattca
     9721 tctccagagc caatctctga ataaccgtaa tagccttctg gatctttaaa tgttctaaat
     9781 cctagctttt cactgatttc caatacttta tccaaagctt caatcacttt tttaccgaag
     9841 ggatgtcctt gtcctgaatc tgcttcatct agtacggaag gaattcggat caattcgctc
     9901 aatgattcta atgcttgttc atgatgttgt tctgtcacaa attttttcat gatattatcc
     9961 tcctaatatg ttaaaaaggg tcatgtcaaa ttcctccgac acaacctctt cttctcaaat
    10021 aatgacgttt taagcctgct ccatcagcaa gcagaatgtt cttaacaaat gatgaaagaa
    10081 aaaacactca ctgaatggag ctattgactt gtccacgtgc ttatcgatag ccgtttatcg
    10141 gtttcttcat tcttatgata gaccttgtac ttgtatttgt ctaggtttag aacattgctg
    10201 ctacacctag gatcacacag atggctacaa ataatatcgc aattaattta ccggtaaatt
    10261 tccaccacac tgaaacatcg aaacgagcaa ttgctacagc acccattacg atagcagatg
    10321 ttggtgtaat taagtttact aaaccagatg cagattgata agcagtgatt actaaatcct
    10381 taccgacgcc ggcaaattca cccataggtc ccatgattcc cattgttgca gcagctaagc
    10441 cggaagttga aggaatcaag aatgacatag ggatatagaa aataaatgta ataatgatga
    10501 atacacttga agataatgaa cttaatcctt gttcgcccca atgtaagatg gtgtctgtga
    10561 ttaatccatt gttcataacc acttggatac cacgagcaac agctactacg attgctacac
    10621 cgatcaaatc agaagcacca gctaaaaatt cagagacaaa ttcagactct ttcatgccat
    10681 aagtgattgc tactacgatg gacattacta agaataacat agtaatttct gggaagtacc
    10741 agtcacctaa tggaagcatg cttttaccta gaaccgtacc tagtaccgga aggtttgtta
    10801 accagtttgt caatgattca aaaatcgtga aattcgcatt caaggttgtc caaggaatca
    10861 aactgatgat catgatacca aaagtaataa agaacaatac attaacatgt ttttgttttt
    10921 tcgtgattac ttcttgacga ccgattgctt caatatcgaa atgcttcata tcttctttac
    10981 gttggttgta tactaatgat tttgttggat ctttttcgat ctttgatgca taacgataca
    11041 catatacaat agaaatagct aacaaaataa cgaacatcaa gaatcgaaga ccaatacctt
    11101 cacccatcga aatcccaaca gcttgtgaag ctacgcctgt tgcaaaagga tttaccgttg
    11161 aagctagaca gcctacttga gaccctacta atacgattgc tacagctact actgtatcaa
    11221 agcctacagc catcatgact gggatcagta aagcatagaa tggaatcgtt tcttctgcca
    11281 ttccgtaagt agagccgcct aatgcaaata acagcatcaa tactggaata agcatttttt
    11341 cttttccttt gaatttcttc acaactgaag caatcccggc atctagtgcc cctgttttgt
    11401 tgataatacc taaaaatcca ccaacaacca aaatgaagaa agagattggg attgcagcag
    11461 gtgtttcttt agttagctcc cccgctggta cacctagcat cccattgatt ggcgccatga
    11521 aaatatccca cagcccttga ggattttgtt gtactcgttc atatgatcca gcgacgatgt
    11581 tgcctgcatc gtctacacta tagtgcccag ctggtataaa ccaagtaagt acagcgatta
    11641 ctgcaataat aataaataag accgtatacg ctgaaggcat ttgaaatttt ttcttttttg
    11701 tttgttccat cttcttcttc ctttcttttc cgttagagac aacaattttg gctctaatgt
    11761 tattttatca aaaagagtat cagaacaaaa ataataacac gcattttgta aaacttttgt
    11821 tcaaaaagtt cgtttttccc tattccctcc tcttttttca ggtttttaaa gctttcttct
    11881 ttttcattgt agcgtttcct tttttttata aacaaacatt ttcgtctttt aaaaggagaa
    11941 gaatttcaca tttgcaaaga attgattgat ttttatgcat aaatcaaaaa aatactcaaa
    12001 acaaacaaat aaaacgttta cattattgca tgtcttgtat ttttttccaa aaaaaaagac
    12061 caagaaattt cttgatcttt ttgatattta tttgactgct gtatgacgtt gttcgaactg
    12121 atgttgtttt cgacttaacc atggaagaag ttgcgcatgc agcactaaaa agacagcact
    12181 cacgatgaat cctttgatca agttgaaagg aacgatccca atcagtacat agtttgctaa
    12241 agacatgccc agcatctgtg ttgcgttcag ccctaaaaac attaagtaaa gaggcgtaat
    12301 aacgaaataa tttgcgatac tcataaaaat agttagagcg atggttcctg taatgacacc
    12361 taaaaatttg tttcttcctt tatgctgttt ctttacacta aagaaataat aaatcgggaa
    12421 tgtaaagatc gttgttgata agaaactagc agtgtctcct accaaattat ccggagaaaa
    12481 acctgtagtc agcagatgta atactgaacg caagaacgct gttgcaactc cggccgctgg
    12541 accgaataag aacatgctga tcaataccga gatatcacta aaatcgatct tcaaaaaact
    12601 aaaagccggc atgatcggaa aagcaaaata ctgtaaaact aatgcgatcg cagcaaacat
    12661 cgctactgca accattttct gtacacgggt gttcttcatt tgaaatcctc ctgttaggac
    12721 tcctcttcag cgaacttttt gacgtttctc tccaaatgaa aaaactctat tttccaggga
    12781 aaatagagtt agagttattt gatcaagcgt cgtcaaataa gctctatctt ctttatccag
    12841 actatactgt cggtatcgga atttcaccga ttcagctatt tttttgcaaa ataggtcgtg
    12901 gactataacc accggtcggg aatttcaccc tgcccctgaa gacgaacctt atataatttt
    12961 tgtttacata ttcattatac atatctattc aaaaaacgca acatctaaca cttataaaaa
    13021 gtaagtgttc attttgagtg gttcagcaaa ctgctgactt cttttttgtt cagttcacgg
    13081 taatccccag gacgtaggcc ttgtaaagtc agatctccgt atttttcacg ttttagtttt
    13141 tgcacaggaa gaccaactgc ttgaagcata tttttcactt gatgattacg tccttcgtgg
    13201 atcgtcaatt ccacgatact gtggtttgtc ttaggatcca ctgataaaat ttggaattta
    13261 gctggagatg tttttcgtcc ttcgatcttt attccttttg tcaaaggtgc aagcatcgat
    13321 tttgtagcga tcccttttac ctttgcaacg taaactttat ccacttcatg ttttggatgt
    13381 gtcaggcgct gagcaaaatc tccatcattt gtcagtagca agatccccga agtatcgtaa
    13441 tccagtcgac ctacaggata gatacgttct tttaccatcg gcaaaagatc cgtaacaact
    13501 tttcttcctt tgtcatctgc aacagcagaa ataactcctt taggtttgta caataaatag
    13561 taaccgtatt cttcttgata aattgggact tcatccactt ccacagtgtc atgtttccca
    13621 acttttatcc ctaattccct tacaacttgt ccgtttactt ttacacgtcc tgcaaggatg
    13681 aattcttctg cttttcgacg agaagtgatg ccagcgtggg caattacttt ctgcaatctc
    13741 tccattacaa ttattctcct ttattcattc catcaaagaa tagatctggt gacacgtctt
    13801 cttcaagtga aatttccatt tcttgtgtat caggcagttc ttctaatgat ttcaaaccaa
    13861 aataatctaa gaagtagcca gttgttccat ataatatcgg ccgacctggt ccttctactc
    13921 tacctttttc ttcaatcagt ttatgggcag ctagacgctg taccgctcct gaaacctgaa
    13981 ctcctcgaat ctgctcgatt tcagctcttg tgattggctg tttataagcg atgattgcta
    14041 aggtttcgac ggcggcttga gataatgtgt ttgatgtccc ttgcgcatat cgcttaagta
    14101 agggagccag ctctttttta gtcgttaata cataatggct ttccgtttca aaaatatgca
    14161 aagctgagtg cgagttttga gtgtaagatt cttttaattc tttcactaaa cttgtgactt
    14221 ctgcttcgct gagatttaac agtccgctta attcttcatt actgatccct tcctcgccaa
    14281 caataaaaag aagggcttca agttcactta atttcgtcat gttcggtatc tcctactgct
    14341 ggataaagca taattgattc atagttttct ttttgttgcg caatgatctg cccttttttc
    14401 atcaattcta gcaaagccat aaaagtagtg acaacttcac ttttagaagg tgactcaaaa
    14461 aaagaatcga aagtacagcc atgcgcattt ctttttatac gctcttcgat aaataccatt
    14521 cgttcttcga tcgttgtgtc atcgggcgtg atcgtttttt ccactttttg agaaaatttc
    14581 ttacgttcta agattttctg catggcacgg atcaaatcga tttttttgac ttgtcctcgc
    14641 ttcaacggct tttcagcatc cgctaaccca tcgatgttca taggttcttt tgtgtaataa
    14701 agacttcgtt cctctgcttt ttctgtcagt ctttcagctg catatttata tttacggtat
    14761 tctaaaagct gagtgaccaa ttcttctcga ggatcttctt cccataattc ttcatcgtct
    14821 gtgccgaatt cttggacagg aagcaatgtc ttgcttttga ttgccatcaa tgtagcagcc
    14881 atcactaagt attctcctgc aacagctagc tcgagtgttt tcattgtatg gatataattc
    14941 atatattgct ccgtgatcgt agcgatcggt atatcatata tatcgatttc catttgctga
    15001 atcagatgaa gcagcagatc gagaggaccc tcgaatacat ctaatttaat attgatctcc
    15061 gtcaactcat tcactctttc ttctttttct ttgctagcca ttttccaatg taaggctctg
    15121 tgatttcagt tgcacggatg gagacatccg ggtacttttc ctgtaattca tctaacattt
    15181 gaaagcccat attctcaccg cgataagacg gattcaaaga aatgtcatgg atgatcagct
    15241 gatcgttcgt tgcccagtaa ataccaataa tcccttgaat gttggttgaa ccttctggcg
    15301 taaagaaaaa aagttcataa tcgtcttcag attcgtacgt atcaatctcc ttcaacaaag
    15361 aagttttacc tgtcagtttc ttatggaaac tcaatagtcc catagcaatt ttacggtttt
    15421 ctttccggta atgtgttaac atcttctcac cttcctatga ctaagccctt ggaaaatgct
    15481 gcttataaac atccgtcatt cttttcttcg tgatatgtgt ataaatctga gtcgtagaga
    15541 tatccgcgtg acctaacaat tcctgtactg tccgcaaatc agctccattt tctagcagat
    15601 gtgtggcaaa gctatgccgc agcgtatgtg gtgttacttc tttgtaaatc ccagcctctc
    15661 gtactaactg cttcagattt ttccagattc cttgccgaga aagacctttc ccatgattat
    15721 tgacaaatac atgcatttca gatgcgtcct ttacaagtaa tggacgtgct tcgtctaagt
    15781 agcgttccag ccattggatc gcataatcac ctaaaggaat gatccgctct ttatctcctt
    15841 ttccaactgt ctgtaccagt ccaagagaaa gatgaagatc tcccaatttc aatccaatca
    15901 attcactgac gcgcatccca gtagcataca tgacttccaa gattgcacga tctcttatcc
    15961 ctaacgtttt tgtcgtatca ggtgcttcaa tcagcttttc tacttctgtc agagtcaatg
    16021 tacttggtaa tttctgtgct ttcttcggcg tatcgatatg ttgcatcgga tcatgatcag
    16081 tgatacgctc ttgccgtaaa aactgatgga atcttctgag acttgagatc atccgagtaa
    16141 cagttgctgt cgcttttttt tcttcatgca acttctccag aaaacggatg actaaaaagc
    16201 gatcgacatc ctgccatgaa gcaattttct gctcctgtag aaaatgcaag tactgttcca
    16261 aatcacgttc atagctttgt cgtgtattgg cggacaatcc ccgttcaata ttcaagtagt
    16321 ggagataatc gttgatttgc tctttcataa taatccccct catgcctctc tatcatatca
    16381 gataccgctt cattctgata gtctttttcc ataatctgag caaagaaaaa gccgtctaga
    16441 cactcagacg gactggtttc tttt
//
LOCUS       DARPZF010000057        16431 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.060, whole genome shotgun sequence.
ACCESSION   DARPZF010000057 DARPZF010000000
VERSION     DARPZF010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16431
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.060"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(16..1194)
                     /locus_tag="SLE65_002278"
                     /pseudo
     CDS             complement(16..1194)
                     /locus_tag="SLE65_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
     gene            1224..1634
                     /locus_tag="SLE65_002279"
     CDS             1224..1634
                     /locus_tag="SLE65_002279"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449544.1"
                     /translation="MVTLFYRRDFLFSIYTKYFTLSSNIKTSTKLICKLFKLDKISNI
                     DDVKSKILTRKVSEPVKLTAQDKKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSG
                     EKVTFKINFITAISKLEYGKQKKRDNNDQYLPKK"
     gene            1715..2335
                     /locus_tag="SLE65_002280"
     CDS             1715..2335
                     /locus_tag="SLE65_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449545.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            3036..3320
                     /locus_tag="SLE65_002281"
     CDS             3036..3320
                     /locus_tag="SLE65_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449546.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            3323..4240
                     /locus_tag="SLE65_002282"
     CDS             3323..4240
                     /locus_tag="SLE65_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8449547.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            4233..5015
                     /locus_tag="SLE65_002283"
     CDS             4233..5015
                     /locus_tag="SLE65_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8449548.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            5016..5696
                     /locus_tag="SLE65_002284"
     CDS             5016..5696
                     /locus_tag="SLE65_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8449549.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            5689..6585
                     /locus_tag="SLE65_002285"
     CDS             5689..6585
                     /locus_tag="SLE65_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEI8449550.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            6780..8429
                     /locus_tag="SLE65_002286"
     CDS             6780..8429
                     /locus_tag="SLE65_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEI8449551.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            9023..9958
                     /locus_tag="SLE65_002287"
     CDS             9023..9958
                     /locus_tag="SLE65_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8449552.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            9951..10721
                     /locus_tag="SLE65_002288"
     CDS             9951..10721
                     /locus_tag="SLE65_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8449553.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            11137..12120
                     /locus_tag="SLE65_002289"
     CDS             11137..12120
                     /locus_tag="SLE65_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HEI8449554.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            12567..13601
                     /locus_tag="SLE65_002290"
     CDS             12567..13601
                     /locus_tag="SLE65_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HEI8449555.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTRAGS
                     NQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKILV
                     INGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELGI
                     DQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMFA
                     KTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHMLG
                     KVVVSGPFNG"
     gene            complement(13690..14013)
                     /locus_tag="SLE65_002291"
     CDS             complement(13690..14013)
                     /locus_tag="SLE65_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEI8449556.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(14000..14707)
                     /locus_tag="SLE65_002292"
     CDS             complement(14000..14707)
                     /locus_tag="SLE65_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEI8449557.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            14793..15134
                     /locus_tag="SLE65_002293"
     CDS             14793..15134
                     /locus_tag="SLE65_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HEI8449558.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(15305..16153)
                     /locus_tag="SLE65_002294"
     CDS             complement(15305..16153)
                     /locus_tag="SLE65_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449559.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
BASE COUNT         5203 a         2829 c         3453 g         4946 t
ORIGIN      
        1 ctgcaaaata atgggttact cagtaaacat tgaagctaat gtatccgtca cttgttggaa
       61 gcctttatgg cttctattta agaatttttg attgtatgta tcaaagatgg atactaggaa
      121 acgctctagt gattcttcat tttgaaactg ctcttttctg cggctgtatt tcttgatttg
      181 tttcttgaaa gattcgatta aattagttga gtaaatgctt cggcggatac caggcggaaa
      241 ctcataaaaa gtcaataaat cttgattttt tatcagtgac tgcgtcactt taggataagt
      301 tttttgctac ttctcaatca tactccctaa aaaggtattt gcctcttcct ttgagctagc
      361 ttgataaaca gccttaaaat catcacagat ttcttttcga tctttgacac gtactttatg
      421 agcaatatta cgggaaacgt gaacacagca atgttggtat ttagctttag gataaatctg
      481 gtgaatcgta tctttcatgc cttttaagcc atcggtaata aacagtaaga catcatgaac
      541 ccctctggag taaatgtcct gtaacaactc attccaaacg taggtcgatt cagtcggagc
      601 aatcgcataa cttagtactt ctttagtgcc gtcttctcgt ataccaatgg caatatagat
      661 tgcttctttg gagacggttt gccgttttaa aggaatataa gtagcatcca tgaaaatagc
      721 gacatactta tcatttagag ttctaacttt aaatgcattt acttcttcag tcagcacttt
      781 agtcatgttg gacatggttt ggggcgtgta gtgatgccca tacattttct caatcaagtc
      841 tgcgatttcc gacatggtaa taccttttcg gaagaggtga atgacggtct cctctaaggt
      901 atcattcgtc cgtctataag caggaacagt ctgttgcttg aactcgccgt tgcggtcgcg
      961 cggaatctgg agatgaagtt ccccgtactc ggtcttgacc gtacggtcat aggagccgtt
     1021 acgagaattc cccgtgttaa aaccaatgcg atcgtacttt tcgtaatcga ggaaagccgt
     1081 taactccgtt ttgagaagcg tattgacagc tttttccaaa tggacacgga ataattcatt
     1141 caaatcgcct ttgttcgcta gagtctttag aatttctgta gtaaaatcgt tcatatggaa
     1201 gtcctctttt ctgtgaatgt gttgtggtaa ctctattcta cagaagggac ttcctttttt
     1261 ctatttacac aaaatatttt acactctcgt caaatataaa aactagtacg aaattaattt
     1321 gtaaattatt taagcttgat aaaataagca atatcgatga tgtaaagtcc aagatattaa
     1381 caagaaaagt aagcgaacca gtaaagctaa cggcacaaga taaaaaaaat ggaattgttc
     1441 tttatggtga tgatgcaaag tataactata attgggatac ctcctcagaa gctgaggtat
     1501 taagtattcc tactaccgat acttcagggg aaaaagtcac ctttaaaata aattttataa
     1561 cggcaatttc taagttggag tatgggaagc aaaaaaagag agataacaat gatcaatatc
     1621 tacctaaaaa ataacgaatt aatgatgcat atgttaaagt tgtttttttg aattaaacaa
     1681 ctcaatttat tcagttatat gttcatcgca gcaagtgaac attaatcgag ttataaaatt
     1741 aataggagct aaaaatataa ataaagttcg atcagaattt atttttccag aagatttttt
     1801 taactggttt ttttatcaat tcagtgaatg caagcgactc ttaggtgaga attattactt
     1861 aaaaggaatc ggcggattta tggggaatgt ggctgatgaa caaaatatta taaaaggaat
     1921 atctgaacaa acatcagagc ttacagtaac taaagcattt ataagtaatg gtgaaagttt
     1981 gaaaaatgta actgcgcgaa ttagaaaaga aaatgaagta gacattgttt ttggaattga
     2041 ccatgaatgt aattcagtga tatatgtaac acaatcagca aatttaattc tttttgagaa
     2101 tggttgcaag gacgatttta tggtggtcta tttgtacgat atactaattc caaaacttcg
     2161 ttccttatat atgtcttctg aaagtatttt tgtgagtgaa caaaagggat ctttctcgaa
     2221 aaaaataggt attgaagtaa ttgaatcgat tatgtgtcat aatcatatta cgctagaaga
     2281 attagaaatt ttgatagggc aaaaaaataa taacacgaaa atacaagttt cttagaaatc
     2341 attttttatt gagatatcta gataaatgat ttattcttca atcaaccaac tcgccaagct
     2401 gaggtaatgt tttgaggtaa tgataacata caacttttta taccctagta aaactctata
     2461 aacaaagact tattaatttc gcatgaaata cattcctgta aaatgcaata aaatagagtt
     2521 ttgtttaacc aggtcttaag aaagcccgta aagcttcaca gttctcaaaa cgttaattgc
     2581 gattatcgtt cgagttcacg agttacgaga atcgtactgg gcgaagcaat gctgagcgca
     2641 gttaccttaa tcctaacttt tctggcactt tccacaattt ggaaagtgcc ttttttgtgt
     2701 ttttagctat gttaataggt aggattcttg gtctataata tcattcgatc tataaacaaa
     2761 cgggaaaaag ataaagtatc atcaaacaat attatttatc cgcttctgag gttgtgacag
     2821 aagtggtcag cttcaagaaa taagaaggaa tttacaaaaa ttgcttctca tgtttgataa
     2881 atattgtgac ttgtgaccga ggagttggca ggagaacacc gtttattcgg aagaagggat
     2941 tgtgaaaagt cttttgtcat aacctcttat ttggtagcta attgtaaatc ccaaacggca
     3001 tgtattattt ttcataagtc cgtttttaag gattaatgtt ttcttttgct ttttatatgg
     3061 tctggcttca gcgagaagtt ccaacgcata tacaaggacg tctgatgtca acgataacaa
     3121 cgattaccat ggtggccagt ccacttggat tagcactgtt tggtgcgctc tttgattggc
     3181 agacaactca accacgtctg cgagacagtc tgatttttct tgaaattcaa ttggaaaatt
     3241 tacactttct ttatacattt ctggctgctt tctttatacc cgtcaactat acttcactta
     3301 tcaataagaa agaaggataa gtatggattt tggaaatgaa acggtcttga aagcaactgg
     3361 tataaccaaa aaatacggtg ctgccaaagc attagataaa gtatcgatcg aaatcaaacg
     3421 tggaatgatc tatggtttga ttggggagaa tggagcgggt aagtctacct ttatgagaac
     3481 tattatgggt ttgatctcga ttgatgaagg ttcgatcgaa ttatttggaa cgacggattt
     3541 gcaggcagca agacgacgta tgggtcaatc gattgaaacc cctgctcttt atccagaatt
     3601 aactgcaaga gataacctac gtatccaagc agcgaacggc ggtgtgtcgg atagagaaat
     3661 cgaagacctg ctgaaaatga tgcgattgga aaatacaggg aaaaagaaag caaagaattt
     3721 ctctttaggt atgcgccagc gtttagctat tgcaaatgca ctgatcacga atccagaatt
     3781 tttgattttg gatgaaccga cgaatgggat ggatccagca gggatggcag aaatgcgaga
     3841 aatcatccaa cgtttggtaa aagaacgggg catcaccgtc ttgctttcta gccacttgct
     3901 agatgaattg tcacagatcg ccactcacta cggtattttg catgaaggac acttgatcaa
     3961 agaattatcg aaagaagaat tggcacaaga atctcgtcaa tttataaaaa ttgacacttc
     4021 ggcgacggaa caagcagtaa cggttctcga ctctcttggt tatagggatt attttgtcca
     4081 atctagccgt gttatccagc tttttgaagg aattgaccaa gtagcagcca tcaatcaagc
     4141 attggtagag gcaaaagttc ctgtggatgg tatccaccta gttgggcaaa aactggaaga
     4201 ttatttctta caattaactg gaggcaatcc acatgtttaa tctattaact gctgaaaaaa
     4261 taaaagtatg gaagagccgt aaaatgtggg tctcactagg actgatggtc gtacttccgc
     4321 ttttttattc ttggaacgaa tggtatatgc atacaaaata cggcaatgaa ttaaaccaag
     4381 caacggatac agtcatcaac ggtgcaacag ggattttaat ggtggaaaaa atggctgcat
     4441 ggattcttct ggctttcgca gcatttgcgt gcttttatat tggggaagaa tttcaaaacg
     4501 gtacgattcg caatacgtta tctttaggac ggaatcgaat gacttattat gtgtcgaaac
     4561 ttctcgttac gcttttgatc acaacacttg gcgtggtttt gattacgggg ctagccatga
     4621 ttgcttacac acttgctttc ggatttggtg aagttgaggg aatcaaaaac tatggaaatt
     4681 atgttctaaa agtatttcct gtattgcttc tgctgatatt agcgacatta tctgttccag
     4741 tggctttgac attcatcact agaagtacca gtgtcagttt gcttctttct tttctttata
     4801 tcatgggaac ggccttcgtt cccggtgttt tcgcaaaaat caaaggcttg gaatttctaa
     4861 cggagtggtt tacggaaacg tggctcatgt atacggactt tgcgcaacaa gcaacttatt
     4921 cgcaagcacc gaaaatgatt ctggtcagtc tagtaacaat cgtggtatca tcagctctag
     4981 gaatgtttat tttccaaaaa tctgacatta agtaggtgtt cctgctggaa actattttga
     5041 ttatcgaaga cgatgaagct gttcattctt tactggagga ggttcttgaa cagagataca
     5101 aacttcttga tgcttattca ggtacggaag gaaaattatt gttaagcaca tatcctgtcg
     5161 atttgatcct tctagatctc atgcttccag ggctttcagg tgaagcattg ttagcagaaa
     5221 tccgacagac atcgaatgtt ccgatcatcg ttctttcagc aaaaagcgat caaagagata
     5281 aagtttcctt gttggcagca ggagcggatg actatgtgac gaaaccattt gatatcgaag
     5341 aactgttgtt acgaatcggc atccaacttc gtcatcagac ttctgtccaa gtaaaagatc
     5401 tgtcgcaacg catctattac aaggaaatct tactggacaa agagtcgagg gatgtaaatg
     5461 tgaatggtgt ggctgtccat ttgacaggaa gagaattcga tctgctgaag ctttttttag
     5521 aacatccgaa aaaagtattt tcgcgagcaa atctttatga aacagtttgg caagaaccat
     5581 attttgatag tgagaaaaca gtgaatatgc atatttccaa tcttcgaggg aaactagcaa
     5641 aggcacatgc tgtgtatatt catacggtgt ggggagtggg gtttagattt gattaagtgg
     5701 ctgttgcttc tcgttgttat ctttatggga agttttattt tcttcctgca aagggaaatc
     5761 aagagattaa ctaagaaaat cgccactctt tctgaacgac aagaatatgg tggtcgtctt
     5821 tcagtcgaat ttcgagaaaa gaatctaatg gacctagtag atgcactgaa tacatgggtg
     5881 gatgaaaatg aacaaaaagg acaagcattt caagaaatgg aagaaaacat cagactatcg
     5941 atcgtcggcc tttctcatga tctcagaact cctttgactg ctattaacgg ttatgtacaa
     6001 ttactggaac aggtagagga tacggagaaa cgggagaagt atttaacgat catcaaacaa
     6061 tctgttgcaa gattactcag tatgacggat cagttttatg atcttgctcg aatagagacg
     6121 aagcaaaaag aaatggatct ccatacgctt tctttttcta aagaggtgga agaagtattt
     6181 ttctcttttt atgaacaatt ttctgagaaa aatatcgagg tagcgttcgc tgaacactcg
     6241 ataaatacaa ctgtattagc agatccgctc atgttgctgc gagtgctgca aaatatcata
     6301 cagaatttat tgcgttatgc agatggacaa gcaaaggtga cattttcaaa agaggattca
     6361 ttcattcgat taacagtggc caatcctatc aaaccaggag cgcaaacctc tgttgaaaaa
     6421 gtcttccagc gtttttatac cgaaaatacc agccgcacaa atacggaatc tagcggaatc
     6481 gggctttacc tgtcaaaaaa attggtggaa ggaatgggag gagagatgac cgctagatta
     6541 gacgggggca tcttctccat ctccgtcaag ttgcggaggg tttaattggc tctaatttac
     6601 ctgaagtgaa tgacaaaaaa ttgtatctcg ttttaaagac atcttctttt ttggaaggtg
     6661 tttttatttt ggtgtgattg atacgaatta ggtaacgaag acagttattt ttgtaccccc
     6721 ttttcaaata gcgcaacagt gctatactaa aactaacaaa tcaaggaacg gagagggata
     6781 tgggccaaag agaatttatc gttttaatta ttattgcagt tgttatttta ttagttgttt
     6841 tagacatttt ttcacgtttg aaagtaaagg aaacagttcg tagtaattgg ggaaaaattc
     6901 cttatcaacc gagatttgat aaagaagaaa gtttgaagga tgcgtggctc acggagaaaa
     6961 aattccgttc atgggatagt gaaatcgacg atcttacttg gtatgacttg gatatgttcg
     7021 aagtatttga agggatcaac agtacctatt ctagtgtagg ttcagaagcg ttgtatcagc
     7081 gtttacgtag ctttgatttt ggagaagatt atcagttaga aaaactaatt gctttttatc
     7141 aggaaaatcc tcaactgaga gaaagaatcc aatatcaatt cgctcgttta ggaaaaaaag
     7201 atcataattt tgcaaaacaa tatctagcgg atggaaaaag taaaaagatt ggacgcgtag
     7261 gtttatttat ttttcttggc ttgcttccgc tggtgggtgt aggtttgctt cttttagggc
     7321 aagtactagg aatctatcta gcaatcggtg gcttagtatt caatacggtc tattatctag
     7381 tgaagaaaca aacactagaa acagagctga atagcatgag ttatttggtt tcaacgattt
     7441 cagccgccaa tcagttagca aaaatgacga caccacttca aaaagagctg aaacagcaaa
     7501 ctaaaccatt aagagacatc cctaaattag gtttttcatt tcgaatgaag agcgggagtg
     7561 aagcagaatt gatttttgaa tatgtcaaca tcatgttcat gctgccattt atctcctatc
     7621 atttcgttct cactaaatta gaaaagcatt caactgaagc catcaagctg tgggaattgc
     7681 tgggagaatt ggaagttgca gcagccgttt tgaattatcg cacctatatg ccgatcactt
     7741 gccgaccaga gtttactgag ggcggtgtga cagcgaaaga tatctatcat ccattgttaa
     7801 aagaagcggt agttaatcca gtcaactggc agaagaatac attagtcacg ggttccaatg
     7861 catcaggaaa atctacgtat gtcaaaagta tagccatcag ctgtattcta gcacagacga
     7921 tccaaacagc gattgcagaa cagtttaccc tgcaacctgg acatgtgttg acttccatgg
     7981 caatcgaaga tgatttattt gaaggcgaca gttattttgt ttcagaaatc aaatcgatca
     8041 aacgtttgct ggaccaagtg gcttccaaag aacgctgcta ctgcttcgta gatgagattt
     8101 taaaaggaac aaatacgatc gaacggattg cttcttccgc ttcagtcgtt cggtggcttg
     8161 cggagtatcc atctttagca tttgtcgcca cacatgatat cgaattgaca gagattttaa
     8221 agaattattg tgagaatgtc cactttgaag aacaagtaac agaaggaaaa ggaatcagtt
     8281 ttgatttcaa attaaaagaa ggaccttcaa ggacccgaaa tgcgattgcc ttgctgaaag
     8341 ttttgaatta tcctaaatcc atagttgaac aggcccaaaa agaaagtttg ttgttcgatg
     8401 aacagcgtca gtggtatccg tttgattaac tttatcaaac gaagcatgat gcgtgggtcc
     8461 aaaaagacga ttatcaaaag aagtacattg atgccaaaaa agtggcagaa ttcaatggga
     8521 acgagtctgc tgtccagatg atcttggaag atttagcaaa agacgataca aaataaacca
     8581 cgctgtcttc cttctagcag cttttatcga aaaaacttag catcagcgac gagacgcacg
     8641 ttccatggca aagttctccg taaaacaaac agcgaaaaca gaaattgaaa ataactattt
     8701 ccattttatt tatttcggtt aaaataaaag aaaaaagctt tcgataaaag gacggaggaa
     8761 agcttaacat gaataaaaaa gacaagaacc tcagttataa ggatcttcta tatgtcatcg
     8821 tagtagttgc tgtcggtact tttatgattt taaaagttcc agagttgttt agatagttat
     8881 tctatcgaag atgatcatga actagaaaac acatctcctc tttgttagca ggtgtgtttt
     8941 tgtgtggaag ccaagttgtt ttttcatctg ctgtattcca tgatacaatt aagaatcatg
     9001 tctataagga gataggaaat aaatggcaaa tgcgcttgaa ataaataatt tgaaaaagat
     9061 ctatggaagt ggggtcgaag cattgcgggg aatcgatctt tcggtgaaag aaggagattt
     9121 ctatgcgcta ttagggccaa atggagctgg gaagtctaca acgatcggga ttattacttc
     9181 tttagtcaat aaaacatctg gaaaagtgaa tgtcttcggt tatgatctgg acaaggatct
     9241 agttcgagca aagcaacaga ttggattggt tccacaagag ttcaatttta acccttttga
     9301 aacggtccag caaatcgtcg tgaatcaagc aggctactac ggtgtctctc gcaaagaagc
     9361 gatgaaacgc agcgaaaaat atttgaagca gtccaatctt tgggaaaaga gaaatgtccg
     9421 tgcacgtatg ctttccgggg gaatgaagcg aagactgatg attgctaggg cattgatgca
     9481 tgaaccacgt ttgctgatct tggatgaacc aacagcagga gttgacatcg agttgagacg
     9541 cgagatgtgg gagtttctac gagaattgaa cgaaaatggt acaacgatca ttttgacgac
     9601 gcattatcta gaagaagctg aaatgctttg tcgcaacatc ggaatcatcc aatcgggtga
     9661 actgatcgag aatacaagta tgaaagagct tctgtcaaaa ctgcaatttg aaacatttat
     9721 ctttgattta gcgccatatg ataccaaacc tgtgattgaa ggatatgctt gtacatttga
     9781 agatgagcag acaatcgctg tcgaagttga acgaaatcaa ggggtgaacg gaatcttcga
     9841 tcagcttaca agacaaggaa tcaaagttct ttctatgagg aataagtcga atcgtttaga
     9901 agaactgttc ttgaaaatca cagaagaaaa taatcatacg gaggagaaaa atgtttaatc
     9961 tttattttac tgcattaaaa agtttagcta tcaaggaaac gaaccgctat ttgcgtatat
    10021 gggtccaaac actggttccg ccagtgatca cgacatcctt gtattttgtt attttcggaa
    10081 aaatgatcgg tgggcggatc ggtgacatgg gtggtttttc atatatggaa ttcatcgttc
    10141 ctggtttgat tatgatgtct gctatcacta gttcgtatgc caatgtttct tcgtccttct
    10201 tctctcaaaa atttcagaaa aatatcgaag aaatcttggt agcacctgtt cctacgcatg
    10261 tgattatttg gggctttgtg attggtggtg tgggtcgcag tattctcgtc ggctctctcg
    10321 taacgatcat ttccttgttc tttgtaccac ttcatgtgta ttcatggttc atggtcatca
    10381 ttacattatt gatgacggca atcttgtttt cattagcagg actgctcaac gggatttttg
    10441 ctcagtctta tgatgatgta tcgatcgtgc ctacatttgt cttgcagccg ttaacttatc
    10501 taggtggcgt tttctatgcc atctctatgt taccgccctt ttggcaagct gtttcaaaag
    10561 tcaatccgat cgtttatatg atctccggtt tccgttacgg attccttgga acgatcgatg
    10621 tgccagtagc aacatcgatg atcgtacttg tgttattcat cgttgttttg tacgccgtta
    10681 cttggtattt gatcaataaa ggaagaggat tgagaagtta gaaaagaggt tgtgaaatca
    10741 gcgttttgac ctgagtatta gagaaacaaa cgggaaaata gttcctcata ttttgttgtt
    10801 ttttgagcga ataccgaggg tcagctgatt gaacaccgtt tagtggagag gttgtgaaaa
    10861 agctgttctg catcaagtaa taagaacagc caaacaaaaa tagctcctcc tatttttcgt
    10921 ttggttggac ttattaccgc agatgcaagc ttttgaacac catttattcc ggaaaatgga
    10981 ctgtgataag atttttgtca cagtcttttt tttgctcaat cagaaacatc ttttaagctg
    11041 ttcactttgc ttcttttttt gtttcctagt ataatgacaa tgtttttgag aaagattgcg
    11101 acttcactgc ttgatagaat ggagagtaac aaataaatga ctactaattt ttggaaagag
    11161 ctgccaaagc ctttttttgt tttagcacca atggaagatg taacagatgt tgtatttcgc
    11221 catgtcgtaa agcatgcagc agcaccggat gtcttcttta ctgagtttac aaactcagac
    11281 agtttctgtc atccagatgg aaaagacagt gtacgaggaa gattaacatt tacagaagat
    11341 gaacagccga tggttgccca tatttgggga gacaagccag aattttttag agaaatgagc
    11401 attgctatgg cagaaatggg cttccaagga atcgatatca acatgggctg cccagtccct
    11461 aatgtagcag aacgtggaaa aggcagtggc ttgatccttc gtccagaagt agcggcacaa
    11521 ttgattgaag cagctaaagc tggcggtttg cctgtcagcg tcaagacgcg tatcggctat
    11581 acggaaatgt ctgagatgga agaatggatc agtcacctac ttcatcaaga tatagccaat
    11641 ctttctgtcc atttgcgtac gcgtaaagag atgagtaaag tagatgcaca ttgggaagtc
    11701 attcctaaaa tcattgcttt acgtgaccaa atcgctccac aaacactaat cacgatcaat
    11761 ggagatatcc ccgatcgcca gacaggagaa gaattggccg agaaatatgg cgttgatggc
    11821 atcatgattg gccgagggat tttcaagaat ccttatgcat ttgaaaaaga cccgagggaa
    11881 catacagaaa aagaactgat cggactactt cgtctgcaac tagatctgca agatcattat
    11941 tcagaaatca tcccgcgttc catcacagga ctacatcgtt tctttaaaat ctatatcaaa
    12001 ggatttccag gagcaaatga cttgcgagtt cagttgatga atacgaaatc tactgatgaa
    12061 gtacgagaga tcttagagac ctttgaaaaa gaacatccaa cgcttttcag tgaacaatga
    12121 tttcttgctt gaacaccgtg aattagaggt cgtgaaaaag ctgtcctgta tcaagtaata
    12181 agaacagcca aacaaaaata gctcttcata ttttgtcgtt ttttgagcta ataccgaggg
    12241 tcagttgatt gaacaccgtt tatatcagag gttgtgagcc tgccgtttaa ctctgagtca
    12301 caaggagcaa tttcaaaaaa cagcttctca tgtttgatga atattttgac ttgtgaccga
    12361 agagttggta ggagaacacc gtttataaga ggttgtgaca aaagtcttgt cgcaacctct
    12421 tttttaacca aaaaagtgca aatagtttac tttaagtaag agaataatta tgatgaataa
    12481 aaaaggtgga acaaatagca tactatatat attgaaatga acactgtatg gatgctccaa
    12541 cttgatgaag ctaaggagga attcgtatgt cagaaaagga attaatgaag gtagtcggtt
    12601 tttatgaagg gttgccgatc gatgatccaa aaagctttat tgatgaaaaa gaacagatac
    12661 ctgtacccag ttcacgggat cttctggtaa aagtcaacgc agtatctgtt aatcctgtcg
    12721 atacgaaact tcgccaagat aacgggataa gaaatgcttt acgtatctta ggttttgatg
    12781 gagtcgggaa agttgttgct gtaggtgacg aagtgcaaaa attttctgtc ggcgatcgcg
    12841 ttttttacgc aggtacaaca agagcaggaa gcaatcaaga ataccaacta gttgacgaac
    12901 gtattgtcgc tcttgcacca aaaaatcttt cagatgaaga agctgcagcc ttgccgttga
    12961 cctcattgac cgcttatgaa ttgttatttg aaaaatttgg tctaactcca gaagaaaatg
    13021 ccaatcgcgg gaaaaaaatc ttagtgatca acggatccgg gggcgtcggt tcgattttga
    13081 atcaactagc gcattgggct ggcctagaag tctacgcgac tgcaagtccg aagaattttg
    13141 aatggctgaa aaaaacaggt gtagactatc caatcgatta tcatcacgac ttaagtaaaa
    13201 gttttcgtga attaggaatc gatcaagtag agtatgtcgc tgtattattc gatattaccc
    13261 gctactttga tcaaatcaag caccttgtcc gaccatttgg acatgtggga acgatcgtag
    13321 ggatcaaaga gccgttagat ataggtgttt ggaaaaacca atctatcagc ttcgactggg
    13381 agtatatgtt cgctaaaaca gactataact atgaaatcga aacgcaagga gaagctttag
    13441 cgcacattgc tgctttagca aatgaaggga ttatccgcag tacattgagc aaggtctatt
    13501 cagatgggat gaatgcgaag aacttgaaac aagcaaccaa agacgtagaa acaggacata
    13561 tgttaggaaa agtcgttgtt agtggtccgt tcaacggata agcaagaata cgccgatttt
    13621 tttcttattt gactttgata aaaacaagag cgcatgacag taatttgcca taagctcttg
    13681 tttttttatt tataataagc gaatcaacga aagggaaaga attcctgcca agacgatcac
    13741 caataagctt tttgaaagaa tagcagctaa aagtgtagga actgaagcca aagcattttc
    13801 gagattgatc tgcggcagat gtccgatatt ttgggtaaat agactgctga accataaagc
    13861 agacataatg acgatcggga caaaacttaa atactcaagc aacggttgcg gtaaatcgaa
    13921 ttttttcagt aagacaaatg gtaggaccct agaaagccaa gttgctaaag tacaacctaa
    13981 aatagtcagc aatgtaaact caaaagaagg catgtttgat ccacaccccc aatccgcacc
    14041 caatcagtgt tacaactaca atcactaagt tgcttgggat aaaaatcagt ccgacatata
    14101 ccagaatcaa agtgagacca atcaggatca actgtaatcg tttagaggtg tttctatcag
    14161 aaatgacttg aagataaagt aacccgataa acatagcgac gatggcgaaa tccaaaccaa
    14221 actttttcgg atcagtaata aaattcccta aaagtgcgcc aacaagagaa gaacccaccc
    14281 acgtcaaata agaaatccaa ttagctgtat tcatccaacg aaagtttaac ttttgtccag
    14341 tatagttcaa tttattcatt cccagtgcga aactttcatc tgtcagcaat gtgccaatca
    14401 gcagattttg aagcagccga tttttcttga aataaggagc aatcgtcata ctcatcagaa
    14461 tcattcggga attgactaga aaggtcgaga aaacgatgga aagcaatggg ctgtgactag
    14521 caagcatgct gactgtgata aattgggcag aaccagcata gaccagcagg gacatcaacg
    14581 tgacgactag tggatgaaat ccggcagctt tcccaacgat accaaatgca agtccaatac
    14641 cgatataacc gaaaacggta ggtaacgtgt ctttgatcgc agtttttata tctaactttt
    14701 catccaataa caaaactcct ttagcacgac ataaattttc ataattgtcg ttaaacttgt
    14761 gaatattcta aatttttaat gagcatttgt caatggtggg attgaaacgt aaagaactag
    14821 cgggtcgcag atttacacgt attgtttcgg tgggaggagg cgcgaaaaat cttgcatggc
    14881 tacaaatcca agctgatatt ttcgatgcaa cggtctattg tttaagtgtg gaggaaggac
    14941 ctgcattagg cgcaacaatg attgctgcac tagggttagg gtggttcgac acacctgaaa
    15001 gttgttgtca gaattttatc caatatacag atgcagtgga acctctctta caaaatgtag
    15061 aaaagtatca taaaatctat caacaatgcc ggaaaatcta tccagcaacg aaggaaattt
    15121 gtcatgactt ataaaacaaa acgcgtacct aatagtcaaa tgactaatat tgggtacgcg
    15181 ttaagtcttc tttacttcat cctttgcatg attcgtgttt ttaaagcaag gtctgctgta
    15241 tttcttgtgg atttaggatg gttgttatcg tttacttgct atttttcatt gaaatcgtct
    15301 ttctttaccg tttctttagt tttttatcta tttttttctt ttggttagaa aattcttttt
    15361 cccgaaagtc ttctttcagg atttttatag agtagcgttt tgaataagag gcgtcagtat
    15421 gatcgacttg gcagacgaac caagagaaca tttgcctttt ttctgcatga ggtgcttctg
    15481 ctaataattc tttccataaa taataacagt cctctatcag aagaagggtt cgttcatcct
    15541 caggctccca atagaatgtt tcgagagtag caatcacttc attgatcaat tcgaatgcgg
    15601 gaagataggc attttgctga ataagcgatt caactgcttc ttggatgaac tttcgcatct
    15661 ccatgatgaa cttcgctgtt ttcctgtttt tgtttttctt gataatatga tcgtatttat
    15721 ggatgatagt tgttaattta tctgaataat ttattgcatg aaatggcatc ttaactttga
    15781 agcgttcgat aaagtgcgga tgttctataa gaatctctgt taaaagctcc cgtacaagag
    15841 aggaactagc ggaggaaaca agggacgaga gttcggaaag tgagtagttg gattttttta
    15901 ttggacgttc ttcgtaagcg aataagacag cagccatgtg tttgcatttt tttccttcta
    15961 tggcatatag acaatcacaa gtcatgttgg tcttttcatc ccaagtgatc actaccttat
    16021 aatcttccgt gccagaaact gttgcggaca agtacttgct tgtatagttc aaatgacgga
    16081 caaaaccgtg cagatgatag ctgtaaccgc gttccaaaac gttttcagga aaatactcaa
    16141 gccaattatt catctagttc tcctttcatg aaacacttat ttatatttag tataaagaaa
    16201 cgtttaagaa aaaagtagct gattttacat atttgataat cacttttgct cgaattgtca
    16261 aaaattcatt ctccttttct tttcttagag aatgtgagaa aaagtaaaag aatagcgtgt
    16321 tttaaagatg gaactttttt tgttttttat ttatctgaca aaaatgaagt gattttgtta
    16381 gaaataaata attgttccaa ttgataaaag aggtatgatg tatcgcaaag a
//
LOCUS       DARPZF010000058        15177 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.061, whole genome shotgun sequence.
ACCESSION   DARPZF010000058 DARPZF010000000
VERSION     DARPZF010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15177
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.061"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            142..523
                     /locus_tag="SLE65_002295"
                     /pseudo
     CDS             142..523
                     /locus_tag="SLE65_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303242.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            654..1604
                     /locus_tag="SLE65_002296"
     CDS             654..1604
                     /locus_tag="SLE65_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002821555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEI8449560.1"
                     /translation="MLKTYSLTKDTLLVSSESNIKNSSVVYVYGDEREYIESSEHKYD
                     FKIGNILTFDDRVAYDTMIDKNDEKSLLVSFLFPEVHEGGHLDTLTTSVVFLVFKNKL
                     IIFTKQKLKFIPELLSNMVLRDVNHFVEEVLLKIMQKDFYMMLNDLRGVKEKIDDLDS
                     EISTSGSLKPTFGDLLTLQKYMIALSTTYKANHKALDFIKKNFTTIDDIDFSTKKIID
                     DLYDTSDTMDRIILSYSQYLDKLENMINNMISYQLNMIMKTLTEISIVLTIPAIIFGF
                     WGINVHVPFEKSSYGVLAVLIISAILSLICWLLMRRKTYL"
     gene            2122..2577
                     /locus_tag="SLE65_002297"
     CDS             2122..2577
                     /locus_tag="SLE65_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEI8449561.1"
                     /translation="MVQQIVLPIKDSSVLKMVQDTLLDSFRAGRRNYTVFQVGKATLL
                     RVSDVMTLKKSDVYNPDGSVKNATFIHDKKTGKANTLYLKPVQQDLLQYHDWLAQENI
                     NSEWLFPSTAHYDLHITEKQFHKVMAHVGDLLGINLEDKEKKLRVRKPF"
     gene            2918..3520
                     /locus_tag="SLE65_002298"
     CDS             2918..3520
                     /locus_tag="SLE65_002298"
                     /inference="COORDINATES: protein motif:HMM:NF013878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449562.1"
                     /translation="MLDPLFTDETFITFGFGHLVELAEPGHYDEKWQNWKLESLPIFP
                     DRYDFEVAKDKGKQFKIVAELLKKANTIIVATDSDREGENIAWSIIHNANAFSKDKTF
                     KRLWINSLEKDVIRSGFQNLQPGMNYYPFYQEAQTRQIADWLIGMNASPLYTLNLQQK
                     GVQGTFSLGRVQTPTLYLIFQRQEAIENFKKEPFFEVEAK"
     gene            3614..3946
                     /locus_tag="SLE65_002299"
     CDS             3614..3946
                     /locus_tag="SLE65_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase I"
                     /protein_id="HEI8449563.1"
                     /translation="MGNQEGIIADVQTKEKKTNSPSSFSLSSLQSKVNQLYKATASQT
                     LKAMQGLYEAKLLSYPRTDTPFITENEFAYLKANFGKYSGFLGLDLEMLLSLIMIRSN
                     NSTQILTN"
     gene            complement(4097..5076)
                     /locus_tag="SLE65_002300"
                     /pseudo
     CDS             complement(4097..5076)
                     /locus_tag="SLE65_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332307.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(5081..5848)
                     /locus_tag="SLE65_002301"
     CDS             complement(5081..5848)
                     /locus_tag="SLE65_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEI8449564.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            6338..6763
                     /gene="lacA"
                     /locus_tag="SLE65_002302"
     CDS             6338..6763
                     /gene="lacA"
                     /locus_tag="SLE65_002302"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEI8449565.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            6780..7295
                     /gene="lacB"
                     /locus_tag="SLE65_002303"
     CDS             6780..7295
                     /gene="lacB"
                     /locus_tag="SLE65_002303"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEI8449566.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            7306..8238
                     /gene="lacC"
                     /locus_tag="SLE65_002304"
     CDS             7306..8238
                     /gene="lacC"
                     /locus_tag="SLE65_002304"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEI8449567.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTISHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            8241..9221
                     /gene="lacD"
                     /locus_tag="SLE65_002305"
     CDS             8241..9221
                     /gene="lacD"
                     /locus_tag="SLE65_002305"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEI8449568.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            9249..9566
                     /locus_tag="SLE65_002306"
     CDS             9249..9566
                     /locus_tag="SLE65_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011669100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEI8449569.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            9566..11272
                     /locus_tag="SLE65_002307"
     CDS             9566..11272
                     /locus_tag="SLE65_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEI8449570.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTLLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            11414..12820
                     /gene="lacG"
                     /locus_tag="SLE65_002308"
     CDS             11414..12820
                     /gene="lacG"
                     /locus_tag="SLE65_002308"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEI8449571.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            12843..13115
                     /locus_tag="SLE65_002309"
     CDS             12843..13115
                     /locus_tag="SLE65_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEI8449572.1"
                     /translation="MLSDTLEKVQHLFRPGFEKVYIVSFEDCPMIPELEATPLLKCGK
                     WYVSTGKEWICHSDLELSAFEWEFLQSLDVEIRETIHFEVNYLPFQ"
     gene            13136..14035
                     /locus_tag="SLE65_002310"
     CDS             13136..14035
                     /locus_tag="SLE65_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HEI8449573.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDKDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSPLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
     gene            complement(14507..>15177)
                     /locus_tag="SLE65_002311"
     CDS             complement(14507..>15177)
                     /locus_tag="SLE65_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
                     /protein_id="HEI8449574.1"
                     /translation="SRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKTTNVLNRKFL
                     RDNPLEAIVTDLTYVRVGKKLNYVCFILDLFNREILGYSCGEHKDAVLVKKAFSCIKQ
                     PLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAVAESTYKSLKVEFV
                     YQYTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQRILDNELGCANA
                     SEAV"
BASE COUNT         4925 a         2532 c         2917 g         4803 t
ORIGIN      
        1 gcgtttgatt ttcaaacttc gcaacagaac cgatgacact atcgttcttc atcaacgtaa
       61 gttagatttg ttgaaagagc agaaaaaagg atttctacaa aaaatgtttg tttgatattt
      121 taaatagaaa agagagataa agtgaagttt ttaaattttt tgaactataa atatttaaac
      181 tgggtattat atggtattac attatttttt attatttatt acttttttac cgatgatgat
      241 atttttttaa ttttagcaat actttttctt gtttcatcta attttagtga taacttaatt
      301 gaagttctta cagaaccaga aattcggtct atgacggatg aagaacaaca gattattaaa
      361 gctatgattt cggaaaataa gaaagacgta gtagttatca aaaagattag agagtataca
      421 aatttaggtg ttttacaagc caaaaaagta tatgaaaaaa aaaaaaaggg tctataatta
      481 caaattagat aatacattag aagctggaga caagattgtc tagataatgt gtgagataaa
      541 atttttggca ggttatcata cataagacaa aatgttttta aaactgataa cgtatttatt
      601 ccacaacaat tacgcattta tttctgagaa aaatataaag caggaggatt acaatgctga
      661 aaacttattc cttaacaaaa gatacattat tagtttcgtc agaatcaaat atcaaaaatt
      721 cttctgttgt ttatgtttat ggtgacgaac gagaatatat cgaatcttct gaacataaat
      781 atgactttaa aataggcaat atactaacgt ttgatgatcg agttgcatat gacacgatga
      841 tagataagaa cgatgaaaaa agtttgctcg taagtttttt gtttcccgag gtacatgaag
      901 gtgggcatct agataccctg acgacatctg ttgttttctt ggtatttaaa aataagttga
      961 taatttttac aaaacaaaaa ttaaaattca ttcccgaact cttatccaat atggttttac
     1021 gtgatgtcaa tcatttcgtg gaggaagtac ttttaaagat catgcaaaaa gatttctata
     1081 tgatgcttaa cgaccttcgt ggagtcaagg aaaaaattga tgatttagac tcagaaatat
     1141 caacgtccgg ttcactcaaa ccaacgtttg gtgatttatt gactcttcaa aaatacatga
     1201 tagctttgtc aacaacttat aaagctaacc ataaagcgct tgatttcatt aaaaaaaatt
     1261 tcacaactat tgacgatatt gattttagta ctaaaaaaat aattgatgat ttatacgata
     1321 caagtgatac aatggataga atcattttaa gttacagcca atatttggac aaattggaaa
     1381 atatgataaa caatatgatt tcgtatcagc taaacatgat tatgaaaacc ctaaccgaga
     1441 tatcaattgt tttgactatt ccagcaatta tttttggctt ttggggaatc aatgtccatg
     1501 tcccgtttga aaagtcttct tatggtgttt tagccgtatt gattatctct gctatactaa
     1561 gtctaatttg ctggcttttg atgcgacgca aaacatattt gtaaagtatt tgtgataccc
     1621 taatatgatt taaagcagaa tttctttgtt gactttttaa aaggctgatt cctttcaata
     1681 atttaatagc ttcagcggct gctcagaagt caataaattg gactattttt attcagttac
     1741 ttaggcaaca tttgagatac gattgcgatt ataaaaattg atataccaac caatggctgc
     1801 ttggaagact gacatattag cctcgatatc atcgaataac taaatacaga aaaatacaat
     1861 aaatattatc aaactaggga ctatactaga aaacatcagt acattcctta actcagggtc
     1921 tataattaga aaatcgcccc tttgaaaact gattaaaaca gcccccatta tctagtgact
     1981 agataatggg ggctgttttt ttgttaagtg atataataaa ccataaaaga agtttagaaa
     2041 tacggtcctg gtcatcaata aataaacaat ttaattaatt atttatttaa ttatttaatt
     2101 tcagaaaggt atacatgaat catggtgcaa caaattgtcc tacccatcaa agactccagc
     2161 gtcttaaaga tggtacaaga tacacttctc gatagtttcc gtgctggtcg ccgaaattac
     2221 accgtttttc aagttggtaa ggccacgcta ctacgtgtga gtgatgtcat gacattaaaa
     2281 aaatcagatg tctataatcc agacggctct gtcaaaaatg caacctttat tcatgataaa
     2341 aagaccggta aagcaaacac gttatattta aagcctgttc agcaagactt gttgcaatat
     2401 catgattggc tggcccaaga aaatatcaat tctgagtggt tatttccctc gacagcccat
     2461 tatgatcttc atatcactga gaagcagttt cataaggtga tggcgcatgt tggtgatctc
     2521 ttaggaatca acttggaaga caaagagaaa aaattgcgag tcagaaaacc gttttgagat
     2581 atgaacagca tttgccttca cgccttagcg attttaaata atagccttga aagtgattat
     2641 ggaaaagccc tctacgctca atgcaaaatt gacgtagaaa ctatttttga tcgattgaaa
     2701 ggtgtatttg gtatgtgaag aacccatgtc agaggcaaga acgttgcacc tactgacatt
     2761 ggaatgatgc ttatgagcat gaatctaacc aaattatccc ttgaggctag aagaaaagcg
     2821 gaagcttttc aacacaaagc agccaaaaat aaaaaacgcg acgaagcaat cacatttatg
     2881 attattcatc gcgtttttta tatttagagc tagttatttg ctagacccac tatttacaga
     2941 tgaaacgttt atcacctttg gttttgggca tttagtggaa ttagcagaac caggtcatta
     3001 tgacgaaaag tggcaaaatt ggaaacttga atctttgccg atttttcctg atcgatacga
     3061 ttttgaagtt gcaaaagata agggaaagca gtttaaaatt gttgcagaac ttctcaaaaa
     3121 ggcaaataca attattgttg caacagatag cgacagagaa ggtgaaaata tcgcctggtc
     3181 gattatccat aatgcaaatg ccttttcaaa agataaaaca tttaaaagac tatggatcaa
     3241 tagcttagaa aaagatgtga tccgaagcgg ttttcaaaat ttgcaaccag gaatgaatta
     3301 ctatcccttt tatcaagaag cgcaaacacg ccaaattgcc gattggttga tcggcatgaa
     3361 cgcaagccct ttgtatacgt taaatttaca acagaagggc gtacaaggta cattttcact
     3421 aggacgtgtt caaacgccca ccttatacct tatttttcag cgccaggaag ccatagagaa
     3481 ttttaaaaaa gaaccttttt tcgaggtgga agctaagtaa aacaagggtc atttaagggc
     3541 gttctaagcc ccacacagcg ttttaaaacc caagaggagc tttttagctt ttgtttcttc
     3601 taaacaagct aaaataggca atcaagaggg gataattgct gatgttcaaa ccaaagagaa
     3661 gaaaacgaat agtccgagtt cgttttcttt aagtagtttg caatcaaaag tcaatcagct
     3721 ttataaagcg acagcgagcc aaactttaaa agctatgcaa ggactgtatg aagcaaaatt
     3781 attgagttat ccaagaacag atacaccatt tattacagag aacgaatttg cttatttaaa
     3841 agcgaatttt ggcaaatata gcggtttttt aggacttgat cttgaaatgt tgttatcatt
     3901 gataatgata cgttcaaaca acagcaccca aattttgacg aattagtgaa actctatgaa
     3961 aaagacgtag taaaacatgc aacatcctat tctaatcagc tggtaaagct taattaggtt
     4021 atataagctt gaaaataaag ggtttgtcca atatggacaa gcctttttct tatgttttgc
     4081 cacagatttg ccacacttat tgtgtaagag tatcaaggat aggtataatt tgatactttg
     4141 tttttttagt gatgtgcaaa taaatttctg ttacacgact acctctagaa tgccctacac
     4201 ggtcttgaat tgcttctagg ggtattcctt actctgctaa gaaactaata tgcgtatgac
     4261 ggaatatatg ggtcgtaata tgtttattaa aactaagttt attatcaata tcaattcctg
     4321 ctcgttttgg attacctttt cgatttaatt ttccattttc aggtgagttg aggaaattgt
     4381 taaggacact ataatgaaga ggtgttccat tatagtcggg tttatgacga cttttggaag
     4441 taaaaatcca tccattatct ttataatcag gattgaatct catatgttgg tgatttaact
     4501 caatttcctc tttaagaatt tctatagccc ttttagataa ttggacattt cggtaacttt
     4561 gtaagttttt tacattacct tcatagctat tttctgcagc tcctccgtga gtggactgac
     4621 taatgatgat attttgcttt tcaaaatatt gataggcacc aatattttgg agtttcgact
     4681 ctgtaagtca acagggccat tagttagaat acctattggg atgcggtttt tatgtagagc
     4741 cagcagtagt tgatgtatct caggaatcat cgtaatctga tcgagttcat attcatagtc
     4801 agcttggaag tctagagctt ctgtcctaga aatactatcg atgccaaatt cttccatagt
     4861 cttctgacag cgaaaaattc taagctgctc aatactgatg agttttttcg tgtatttagg
     4921 aaaagcaaca tcagaccaat atctgaaacg tttgtaaatg ttatctattt gttggatatc
     4981 aatcgttgga aaacatttct caacgctacg tttaaagggg agttgatggt cataaagagt
     5041 gtcatcaagg tcaaaaacaa tatttttata agtcataatt ctagtccgct tttaaaatag
     5101 tagtgtactg gctaaattcc tctaagtgtt gagggctaat ctggttatct gtaatgatgg
     5161 tatcgagttg atctagatta tagaagttaa agaaatcgta tcgatcgaat ttagtactgt
     5221 ctactaataa gaatttttct acagcattgt ttagggcaag ttgttgaatc acaccttcct
     5281 tgtcactata tgtagcaata gaattatggg taacagcatt tgcactaaca aaagctttgg
     5341 caaatctaat tgcttttaaa tttgtcgaag ccattgaacc tacaaaagct ccagttattt
     5401 ctctatattc accgccaaga agcaataaat caatggtttc gctatcattt agaatcaaga
     5461 acacagggag actatttgta atgacacgaa ttttataacc tttacgacct ttcaattcta
     5521 atgccagttg ttcaagtgta gttccaggtc caataaaaat agtatcgcca tctttgatta
     5581 aagagcaggc ttttttagca atgtcaattt tttcttttgt atttagactt ttcttctcga
     5641 tatgtgtctt ttcaagtggc tttttagagg aaagcaattg tgcaccacca tgagtacgtg
     5701 ttaaaagtcc atcagcttct agagcatcaa ggtctctacg ggctgtcata tcggaaatat
     5761 ctagttcatc tattatttct tttatggtta tggtcccatc aatctttaac atatctaaaa
     5821 ttttttctaa tcgtcgtttt ttgttcatat gaagaccctt ctttcataaa gtaatttttt
     5881 tccaaagata attctctttt aattgtatca taaaagacaa tattttcaag gtaaaacaaa
     5941 caatttcaaa caaaaacaaa tgttagatga tgaaataaga acagaggatt gacgtatatt
     6001 agcttaggtc agattttgta taagacgaaa ataaagtagg acctcttaat cagtaagtta
     6061 tagaaagtaa aagacttttg taatacttga atagatattt cacgtccatt ttgtgatgga
     6121 ttaaatgaac aaaaatgaac aataatttaa cggtgttatc tattttttaa aaaaacaaat
     6181 aaaaaaaaca aaaaataaac aaaaaaagtg ttgctttttg tttgaatgct tgatattata
     6241 taaacaaaga aatgatgaaa acgttttttc gaacattttg caaaatgttt tctacttcta
     6301 cgtagcattt ctttctaaaa tttaggaggt ggtcaaaatg gctattgttg ttggtgcaga
     6361 tctcaaaggt acgagattaa aagatgttgt gaaaaatttt cttgtagaag aaggttttga
     6421 ggtaattgat gtgactaagg acggacaaga ttttgttgat gttaccttgg cagttgcctc
     6481 tgaagtaaat aaagatgagc aaaacttagg tattgtaatt gatgcttatg gagctggtcc
     6541 attcatggta gcaactaaaa ttaaaggtat ggttgcagca gaagtttcag atgaacgctc
     6601 agcttatatg acacgtggac ataacaattc acgaatgatt acggttggcg ctgaaatcgt
     6661 cggtgatgag cttgctaaaa acatcgctaa aggtttcgtc aatggtaaat atgatggcgg
     6721 acgtcatcaa atccgagtag atatgcttaa caaaatgtgt taagaaaagg agttaaggaa
     6781 tgagaatcgc aattggatgt gaccacattg tcacagatga aaaaatggca gtatcagaat
     6841 tcttgaaatc aaaaggacat gaggtccttg atttcgggac atatgaccac gcacgtactc
     6901 actaccctat ctatggtaaa aaagtcggtg aagcagtagt aagtggtcaa gcagacttgg
     6961 gagtatgtat ctgtggtaca ggtgtcggca ttaacaatgc agtcaataaa gttccaggtg
     7021 ttcgctcagc gttggttcgt gatatgacat cagctatata tgcaaaagaa gagttaaatg
     7081 cgaatgttat cggtttcggt ggaaagatta ctggtggtct tcttatgaat gacatcattg
     7141 aagctttcat tgaagctgag tacaaaccaa cagaagaaaa taaaaaattg attgcaaaaa
     7201 tcgaacacgt tgaaacacat aatgcacatc aagcagatga agatttcttt acagaattcc
     7261 ttgaaagatg ggaccgtggt gactaccacg attaaggtat aacaaatgat tctgacagtc
     7321 acactaaatc cttcagtaga catctcttat cctctagaaa cattgaaaat tgatacagtg
     7381 aatagggtga aagatgttag taagacagct ggtggaaaag gcttaaatgt tactagagtc
     7441 ttgtatgaat ctggtgataa agttactgct acaggtttct taggtggtaa aattggtgaa
     7501 tttattgaaa gcgaattaga acaatctcct gttagtccag ctttttataa aatctcagga
     7561 aacactagaa actgtattgc tatcttacac gagggtaacc aaacagaaat tttggaacaa
     7621 ggaccaacaa tttctcatga agaagcagaa ggctttcttg accactatag caatcttatt
     7681 aaacaatcag aagttgtgac aatttcagga agtttacctt caggacttcc caacgattat
     7741 tatgaaaaac ttatccaact tgcttcggat gaaggagtag cagtcgtttt ggattgttca
     7801 ggtgcacctc ttgaaacagt tctaaaatcg tcggctaaac ctactgccat caaacctaat
     7861 aatgaggaac tttcacagtt gcttggaaaa gaagtaacaa aagatattga agaactcaaa
     7921 gacgttctta aagagtcact ttttagtggt atcgaatgga tagtggtctc attaggtcga
     7981 aacggtgcct ttgcaaaaca tggtgatgtt ttctataagg tagatattcc tgatatccca
     8041 gttgttaatc cagtcggatc aggggactca acggtagctg gtattgcatc agctttaaat
     8101 agtaaaaaaa gtgacgctga cttattaaaa catgcgatga cattgggtat gttaaatgct
     8161 caagaaacaa tgacagggca tgtgaatatg actaattacg aaacactaaa ctcacaaatt
     8221 ggagtaaaag aggtataaaa atggtactta cagaacagaa acgcaaatct ttggaaaaaa
     8281 tttcagataa aaacggtgtt atctcagctt tggcatttga ccaacgtggt gctttgaaac
     8341 gtttgatggc acagtatcaa gatacagaac caactgtagc tcaaatggaa gaactaaagg
     8401 ttttggttgc tgatgaactt acaaaatacg cttcttcaat gttgcttgac cctgaatatg
     8461 gacttccagc aacaaaagca ttggataaag aagcaggtct tcttcttgcc tatgaaaaaa
     8521 caggttatga tacatcaagt acaaaacgtt tgcctgactg cttggatgtt tggtctgcaa
     8581 aacgtatcaa agagcaaggc gctgatgccg ttaagttctt gctttactat gatgtagaca
     8641 gctcagatga acttaaccaa caaaaacaag cttatattga acgtgttggt tctgaatgtg
     8701 tcgctgaaga tattcctttc ttcttggaaa tccttgctta tgatgaagaa atctcagatg
     8761 caggttctgt tgaatatgca aaagtgaaac ctcgcaaagt cattgaagcg atgaaagttt
     8821 tctctgatcc acgctttaac attgatgttc ttaaagtaga agtaccagtt aacgttaaat
     8881 atgtcgaagg ttttgctgat ggtgaagtag tttacagtaa agctgaagct gctgacttct
     8941 ttaaagcaca agaagaagcg actaaccttc catacatcta cctaagtgca ggtgtatctg
     9001 ctaaattgtt ccaagaaaca ttgcaatttg ctcacgactc aggtgccaag tttaatggtg
     9061 tgctttgtgg acgtgctact tgggcaggat ctgtagaacc ttacatcaaa gaaggtgaaa
     9121 aagcagcacg tgaatggttg cgtactactg gattcgaaaa tattgatgaa cttaacaaag
     9181 ttcttgttaa aacagctagt ccatggactg ataaagtata gtaaaaacat aaaacggagg
     9241 atattgttat gaacagagaa gagatgactc tcttagggtt tgaaattgtt gcttatgctg
     9301 gagatgctcg ctctaaactt ttagaagcgc ttaaagcggc tgaaaatggt gatttcgcta
     9361 aggcagatag tcttgtagta gaagcaggaa gctgtattgc agaggctcac aattctcaga
     9421 cagctatgtt ggctcgagaa gcttctgggg aggaacttcc atacagcgtt accatgatgc
     9481 atggtcagga ccacttaatg actactgtct tattaaaaga tgtgattcat cacctcatcg
     9541 aactttataa aagaggagca aaataatgca taaactcatt gaacttattg agaaagggaa
     9601 accgttcttt gagaaaatct ctcgaaacat ctatcttcgt gctattcgtg atggatttat
     9661 cgctggtatg ccagtcatcc ttttctcatc tatctttatc cttattgcct atgtcccaaa
     9721 tgcttgggga ttccactggt caaaagacat tgagaccttc ttgatgactc cttatagcta
     9781 ttcgatgggt atcctagcat tctttgttgg tggtactacc gctaaagctt tgacggactc
     9841 aatgaaccgt gacctacctg cgaccaatca gattaacttc ttatctacga tgctagcgtc
     9901 tatggtaggg ttccttttga tggcagctga gcctgcaaaa gaaggaggct tcttgacagc
     9961 cttcacggga acaaaaggtc ttttgacagc atttattgca gcctttgtga cagttaatgt
    10021 ttacaaggtc tgtgtgaaaa ataatgttac tattcgtatg cctgaagagg ttccaccaaa
    10081 tatctctcaa gtatttaaag acttgattcc attcactgta gcggttgttc tcctttatgg
    10141 atttgaactc attgttaagg gaactcttgg tgtaaccgtt gcagaatcaa tcggtaccct
    10201 tcttgctcct ctcttctcag ctgcagatgg ttaccttgga attacactta tctttggtgc
    10261 ttatgccttc ttctggtttg ttggtatcca cggtccttca attgtcgaac cagcaatcgc
    10321 tgctatcact tatgccaata tcgatgccaa cttgcatctt atccaagctg gacaacatgc
    10381 agacaaagtt atcacttctg gtactcaaat gtttattgtt accatgggtg gaacaggagc
    10441 tacattgatt gttccattct tgttcatgtg gatttgtaaa tcagaacgta accgtgccat
    10501 cggacgtgcc tcagttgttc caacattctt tggggttaat gagccaatct tatttggtgc
    10561 accaatcgta ttgaatccga ttttctttgt accgttcatt ttcgctccga ttgtcaacgt
    10621 ttggatcttt aaattctttg ttgacacatt gaacatgaac tcattctctg ccaaccttcc
    10681 atgggttact cctggtccgt tgggaattgt actcggtact aacttccaag ttctatcatt
    10741 tatcttagcc ggactcttgg tagttgttga tactatcatt tattacccat ttgttaaggt
    10801 atacgatgaa caaattcttg aagaagaacg ttctggtaaa acaaacgatg ctcttaaaga
    10861 aaaagtagct gcaaacttca atactgctaa agcagatgcc gttcttggaa aagcaggcgt
    10921 tgctaaagaa gatgtagcag caaacaataa tatcacaaaa gaaactaatg tccttgttct
    10981 ttgtgcaggt ggaggtacaa gtggcttgct tgccaatgcc ttgaacaaag cagcagcaga
    11041 atacaatgtt ccagtcaaag cggcagcggg tagttacggt gctcaccgtg aaatgttgcc
    11101 agagtttgac ttggttatct tggctccaca ggtcgcttca aacttcgatg atatgaaggc
    11161 tgaaacggat aaattgggca ttaaacttgc aaaaactgaa ggagctcaat atatcaaatt
    11221 gacacgtgat ggacaaggtg ctcttgcatt tgttcaacaa cagtttgatt aataaatttg
    11281 taaaagttat ttgagacgag attattcttt caattcctta taatattgtt aaccatatca
    11341 ttgcatttca tttccttggt ttccggaact cagaatatcg tctcaaatgc tttttttgaa
    11401 aggatttata gttatgacta aaacacttcc taaagatttt atttttggtg gtgctacagc
    11461 tgcttatcaa gcagaaggtg cgactcacac ggatggtaaa ggcccagttg catgggataa
    11521 gtatcttgaa gacaattatt ggtacacagc agagcctgca agtgattttt accataaata
    11581 tcctgttgat ttagaattag ctgaaaaata tggcgttaat ggtattcgta tttcaattgc
    11641 ctggtctcgt attttcccaa ctggctatgg cgaagtaaat gaaaaaggtg ttgaattcta
    11701 ccataatctt tttgccgagt gccacaaacg tcatgttgag ccattcgtga ctttgcacca
    11761 ctttgacaca ccagaagttc ttcactcaga tggagatttc ttaaaccgcg aaaatataga
    11821 acactttgta gattatgccg ctttctgttt tgaagagttc ccagaagtaa actactggac
    11881 aactttcaat gaaattggcc caattggaga tggtcaatac ttggttggta aattccctcc
    11941 aggcattcaa tatgatcttg ccaaagtctt ccaatcacac cacaatatga tggtttctca
    12001 tgcacgtgct gtgaaattgt ataaagataa aggttataaa ggcgaaattg gtgtagtaca
    12061 tgcgttgcca accaaatacc cttatgatcc agaaaatcca gcagatgttc gtgccgctga
    12121 gttagaagat atcatccata acaaatttat cttggatgca acctaccttg gacactattc
    12181 agataaaacg atggaagggg tcaaccacat cctagctgaa aatggtggag aacttgatct
    12241 tcgtgatgaa gacttccaag cacttgaagc agctaaagat ttgaacgatt tccttggtat
    12301 caactactac atgagtgatt ggatgcaagc ctttgatggt gagactgaaa tcattcacaa
    12361 tggtaagggt gaaaaaggaa gttctaagta ccagattaaa ggtgttggtc gccgaatcgc
    12421 accagattat gtgcctagaa cggattggga ctggattatt tatcctgaag gcttgtatga
    12481 ccaaatcatg cgagtgaaaa atgattatcc aaactacaag aagatttaca tcactgaaaa
    12541 cggtcttgga tacaaagatg agtttgtaga taataccgtt tatgatgatg gtcgtattga
    12601 ttacgtgaag aaacacttgg aagttttatc agacgcaatt gcggatggtg caaatgttaa
    12661 aggttacttc atctggtcac ttatggatgt cttctcatgg tcaaacggat acgaaaaacg
    12721 ttatggacta ttctatgtag actttgacac gcaagaacgc tatcctaaga aatcagctca
    12781 ttggtataag aaagtagcag aaactcaagt gatagagtaa tattacttga aaatgtaaaa
    12841 aattgttatc cgatacttta gaaaaagtac aacacttatt tagaccaggc tttgaaaagg
    12901 tatatattgt tagtttcgaa gattgtccta tgattcctga gcttgaagct accccgttgc
    12961 taaaatgtgg taaatggtat gtttcaactg gaaaagagtg gatttgccat tctgatttag
    13021 agttatcagc atttgaatgg gaatttttac aatcactcga tgtagaaata cgtgagacta
    13081 ttcacttcga ggtaaattat ttgcctttcc aataataaaa agaaaggaat tagttgtgac
    13141 tatcgaatta aaaaacgagt atcttactgt tcagtttaaa acacttggtg gtcaactgac
    13201 ttcgattaaa gacaaggatg ggatagagta tctctggcaa gctgatccaa attattggaa
    13261 tggacaggcg cctattctat ttcctatctg tggtagttta cgaaatgatt gggctattta
    13321 tagacctcaa gaaagaccct tttttacagg tcttattcgt agacatggtt ttgttcgaaa
    13381 agaagaattt attctggaag aagtcaatga taatagcgtg acctttagta ttaaaccaaa
    13441 tgctgagatg cttgataatt acctatatca gtttgaactg agagttgttt ataccttgaa
    13501 tggtaaatca attagaaccg aatttcaggt aacgaacttg gaaatggaaa aaacaatgcc
    13561 ttactttatt ggagcccatc cagcattcaa tagtccttta gtagaaggtg aaaactatga
    13621 ggattattat attgaattta gtgaggttga gtcttgctcg ataccaaaga gttttcctga
    13681 gacaggatta ttagatttgc aagatcggac accttttttg gaaaatcaaa aaattctcga
    13741 tttggactac tcactttttt cccatgatgc cattacactt gaccagctca agtctcgtag
    13801 cgtaacgctt cggtcaagga agtctggtaa aggtcttcga gtagattttg atgattttcc
    13861 gaacttgatt ctgtggtcta caactaataa aagtccattc attgctttgg aaccttggag
    13921 tggtctctcc acttcacttg aagaaggtaa tttcttagaa gataaaagac aggtaacgaa
    13981 aatttcacct caagaaactt ctagaaaaat ctatgatatt actatcctta attaaaattt
    14041 gttattattt gagtcttcaa taagatttga atactcttac cttgtgatga tagattggtc
    14101 ttctccgtgc cagtcttaca tcgcaaggtt tttaagtttt ttgtgggtct atgtcaactg
    14161 tagtgggtga cgaaaagcta atatctaaag acagtctggt agtaaaaaat aagattattt
    14221 actacttctt gatttaaaat aatagtggag ccattaattt gtggcaaatt taatttaata
    14281 ttttgcctca aattagccac actttttata gaactaagag gaaaaatgaa attttcttcc
    14341 tattaatata gttgtttgaa atcttaaata tagcgttttg gaatggcaac agtttttttg
    14401 acaaatttta taaggtgcag aacttctttc cgtatgctat tccgattgtc cttgacaatg
    14461 agcctcctcg gatgtgacga tcttcggcag gagctaacag ttaaagttag actgcctcgc
    14521 tagcgttagc acatccgagc tcattatcaa ggattcgctg cgccaatctc tggttacggt
    14581 aaccaaccgg tgtctcgtag ccaagtgtac cgtgcaaccg aaggtggttc caccaattga
    14641 catagtcaaa taactccaaa tccaattgtt gtaaggtttc aaatgtgtat tgatagacaa
    14701 attctacttt cagcgactta taagttgatt cagctacggc attatcaaaa ggacagcctt
    14761 tatgactcaa tgatcgattg atgtcaaaag ttgttaataa ttcatcaata gcttggttat
    14821 caaactcttt tccacgatca gtatgaaaaa tctcaacctc tgtcagaggt tgtttgatac
    14881 agctaaatgc tttttttact agaacggcat ctttatgttc tccacaagaa tagccgagaa
    14941 tttctcgatt gaacagatcc aaaatgaaac agacataatt caattttttc ccgactcgta
    15001 cataagtcaa gtctgttacg atcgcttcta atgggttgtc tcttaagaat ttacgattca
    15061 atacgtttgt cgttttggct tcattgcaag tagaatgatg tactttaaaa taagcaacag
    15121 tatagctcga ttttaatcct ctatttttca tgattctact aatttttcgt cggctga
//
LOCUS       DARPZF010000059        14901 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.062, whole genome shotgun sequence.
ACCESSION   DARPZF010000059 DARPZF010000000
VERSION     DARPZF010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14901
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.062"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     misc_feature    111..236
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            280..804
                     /gene="infC"
                     /locus_tag="SLE65_002312"
     CDS             280..804
                     /gene="infC"
                     /locus_tag="SLE65_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEI8449575.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            876..1076
                     /gene="rpmI"
                     /locus_tag="SLE65_002313"
     CDS             876..1076
                     /gene="rpmI"
                     /locus_tag="SLE65_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEI8449576.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            1129..1488
                     /gene="rplT"
                     /locus_tag="SLE65_002314"
     CDS             1129..1488
                     /gene="rplT"
                     /locus_tag="SLE65_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEI8449577.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            1740..3047
                     /locus_tag="SLE65_002315"
     CDS             1740..3047
                     /locus_tag="SLE65_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HEI8449578.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAIFA"
     gene            3124..5253
                     /locus_tag="SLE65_002316"
     CDS             3124..5253
                     /locus_tag="SLE65_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HEI8449579.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKQQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            5228..5917
                     /locus_tag="SLE65_002317"
     CDS             5228..5917
                     /locus_tag="SLE65_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449580.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(6325..7011)
                     /locus_tag="SLE65_002318"
     CDS             complement(6325..7011)
                     /locus_tag="SLE65_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8449581.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(7147..7341)
                     /locus_tag="SLE65_002319"
     CDS             complement(7147..7341)
                     /locus_tag="SLE65_002319"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449582.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(7391..7831)
                     /locus_tag="SLE65_002320"
     CDS             complement(7391..7831)
                     /locus_tag="SLE65_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HEI8449583.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(7835..8680)
                     /locus_tag="SLE65_002321"
     CDS             complement(7835..8680)
                     /locus_tag="SLE65_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEI8449584.1"
                     /translation="MLINEQLVKRIITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            8829..10247
                     /gene="pepV"
                     /locus_tag="SLE65_002322"
     CDS             8829..10247
                     /gene="pepV"
                     /locus_tag="SLE65_002322"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEI8449585.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(10304..11251)
                     /locus_tag="SLE65_002323"
     CDS             complement(10304..11251)
                     /locus_tag="SLE65_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEI8449586.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(11474..11824)
                     /locus_tag="SLE65_002324"
     CDS             complement(11474..11824)
                     /locus_tag="SLE65_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEI8449587.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            12024..13103
                     /gene="pepA"
                     /locus_tag="SLE65_002325"
     CDS             12024..13103
                     /gene="pepA"
                     /locus_tag="SLE65_002325"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEI8449588.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            13247..13567
                     /locus_tag="SLE65_002326"
     CDS             13247..13567
                     /locus_tag="SLE65_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEI8449589.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            13589..14053
                     /locus_tag="SLE65_002327"
     CDS             13589..14053
                     /locus_tag="SLE65_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEI8449590.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            14258..14863
                     /locus_tag="SLE65_002328"
     CDS             14258..14863
                     /locus_tag="SLE65_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HEI8449591.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
BASE COUNT         4740 a         2749 c         3115 g         4297 t
ORIGIN      
        1 ggaatcactg ctagaaagtc tgctaatcta atcattttca gaaaaggaag acaaactgta
       61 tgaaaaacat tgacaaaaag attagttttt gctatactat gatggttgag aaataaaagc
      121 agaagcaccc gcttctcgcc ttagttgata atgtcactgg gctagatagt tttcactggt
      181 tctattaggt gaagtacgcg cgggttctgt aagagaactc gtttttttat tgccgtttat
      241 tcggtaagct tttctttctc tcataatatt tggaggtgaa tgaccatagc aaaggatatg
      301 atggttaacg acggcattcg tgcacgagag ttacgattga tcggttcaga tggtgagcaa
      361 ttaggagtta agacaaaagc agaagcattg aatattgcag aacaagcaaa cttggatctt
      421 gtgttagttg cccctggtgc gaaaccacca gttgcgcgaa tcatggacta cggtaaatac
      481 cgtttcgaac aacaaaagaa agaccgcgaa gcgcgtaaaa aacaaaaagt gatcaatgta
      541 aaagaagttc gcttaagtcc tacgatcgac ttgaatgact tcaatacaaa acttcgtaat
      601 gcacgtaagt tcttggaaaa gggcgataaa gtgaaagctt ctatccgttt caaaggccgt
      661 gccattaccc ataaagaaat tggtcaaaaa gtcttgaatc gcttagctga agaaactgcg
      721 gatattgcaa cagtggaaca aaaagcgaaa atggacggac gcagcatgtt cttgacgctg
      781 gcaccgaaaa acgacagtaa gtaatttgaa tgactaactg gctgttggac agccgatagt
      841 cggataacga aagattttga ggaggaaata tagtcatgcc aaaacaaaaa acacaccgcg
      901 gatcagcaaa acgtttcaaa cgtactggta aaggcggatt gaaacgcttc cgcgcgttta
      961 caagtcaccg tttccacggc aaaacaaaaa aacaacgccg tcaattgcgt aaagcaagca
     1021 tggtttctag tggcgacttc aaacgtattc gccaacaact agcaaaaatg aaataagaag
     1081 tacaaataac agaatctgaa gatttatttt tattaggagg aattatacat ggcacgtgtt
     1141 aaaggtggaa cagtaactcg taaacgtcgt aaaagagtgc taaaattagc aaaaggttac
     1201 tacggttcaa aacacacttt atttaaaaca gcaaaagaac aagtaatgaa ttcatacaac
     1261 tacgcatatc gcgatcgtcg tcaaaagaaa cgcgacttcc gtaaattgtg gattgctcgt
     1321 atcaacgcag cagctcgtat gaatggcttg agctactcaa aattaatgca cggtttgaaa
     1381 gttgctgaaa tcgacatcaa ccgtaaaatg ttagctgact tggctgttaa cgatgcagca
     1441 gcatttactg cattggctga ccaagcaaaa gaagctttgg ctaaataagc taaacaatta
     1501 taaagaggaa agaagataac gaaaagttat gttctttcct ctttttttat ttacaatcct
     1561 ccatcaaatg aaacaggaca ataacgtata agtctaaaat agcataatta aggtttttta
     1621 attgaaaact gaacatttat ggtcaccctt taatgaaagc gctaactaca taagttagaa
     1681 tgagtttgac tgatatatta gtttgcttat cagaaaaaca aaatggacgg aggaataaca
     1741 tgagtgatat tattattggt attttgttag ttatctcatt ctttttcatg gtctggtact
     1801 gtgtaaaagg ctacaacttg atggtcggct ttgccatcat ggctactgta tggatgggat
     1861 tagcgctagt cggaaacacg ttttcaccaa acccggcgat ggaagggcaa ggagtaattg
     1921 atgtgttgac gcatatctat acgacggggc cagctgagta cgccaaatcg atcttggtaa
     1981 atgtcttctt tggtgccttt ttcgggcgtg ttctagtaga tagcggaatc gcagctaccc
     2041 tgattcgaaa ggtagttgaa cttggagggg acaagccaag aatcacgatg agcttactat
     2101 gtattgtaac cgctgttata ttcatgtcga tgacaggaat cggaccagtg atttctattg
     2161 cagttattgt gttgccaatc ttgatgtcat taggtatttc agtaccggtt gcactgttct
     2221 catttatggg ctcgattatg gctggaatct ttgctaatat cgtcaatttc aaacaatatc
     2281 aaacgattta tgctggtttc aatccagcgg ctgaaagcta tacttataat gactatttcc
     2341 aaattggtat gattgggatg attgtaagct tagttgtggt actaacggtc gctaatatat
     2401 caatgaacaa aaagaaacgc tatgcaatgg cagcaaacgt accagctgaa ggtggcgacg
     2461 caccaatgat ctcatggtta gccgtattat taccagtttt aggggtcgtt cttttagatc
     2521 ttccaatcat cttaggtttt attctagcag gtatctgggc attgctgttt actggaaaat
     2581 tgcgcggagg ttataaagaa atctgtcgtc agtttgcgaa attatttaca gatggcgcag
     2641 tagatgttgc accaatggtt ggtttcttga tgaccttagc gatgttcaat aattcagctg
     2701 cgtatgcttc tccttatttt tcagctattt ttggagattg gataccgcaa tcaccattag
     2761 tcttggcaat cgtatttgct atattgacac cactaggatt tttccgcggt ccaatgaatc
     2821 tagtcggttc aggctcagct attttagctg tcgtattagc tgttaatcca acgatgtcgc
     2881 cagccttttt gttcccgtta tttgcaatca caacgattgc tcctcagcat ttagatatta
     2941 cacaatcttg ggttgcttgg ggattaggtt atacaaaagt aacttctcga gaatatatga
     3001 agaaatccat cccaactggt tggatcatcg gagcgatctt tgcctgatca cgttcttatt
     3061 gtacgggaac gcctagtaaa caaaacgtcg ataaaaacga ttagatgaat ggaggaaaag
     3121 aaaatgaaac gttttgtgcg aatgggaatt gatgttggcg gtacacatac gaaagcagtc
     3181 gcaatcgata atgcgacgca cgaaatcatc ggaaaatctt cagtgaaaac aacccacgat
     3241 gatgtccgtg gagtagccgc aggtgtcgtt cagtcttttc aaaattgttt gcgggaaaat
     3301 aatatcagtc cagaagatgt tgtgtttgtt gcacattcta ccacacaagc gactaatgca
     3361 ctgattgaag gagacgtagc aaaagtcggc gtaatcggga tggcaaaagg tggattagaa
     3421 ggttttttag caaaacaaca aactagattg aacgatatcg atttagggaa taagaaaaaa
     3481 atagagattg tcaatgcatt cttacctgtc aaacacttaa atgtagaccg tgtttcagaa
     3541 acgatttctt ctttagaaag agaaagagcg gaggtcttgg tttcttctat ggcatttgga
     3601 gtagataatg gggaaccaga acgagttgtt tatgaagcag catcggtaaa atcgatccct
     3661 acaacgatgg cttctgacat cacaaaatta tatggattga caagaagaac tcggacagca
     3721 gcaatcaatg catctatttt accaaaaatg ctagatacgg caacctctac agaagattcc
     3781 gtacgagaag caggggtcaa tgtttctttg atgattatgc gcggagacgg cggagtaatg
     3841 gaaatcaatg aaatgaaaaa acgacctgtt ttaaccatgc tttccggtcc agcagcatca
     3901 gtcatgggct ctttgatgta cttgagagcg tctaatggtg tttattttga agtaggcgga
     3961 acaacaacca atatcggggt cattaaaaat ggacgtccag caatcgatta ttcaattgta
     4021 ggtggccacc caacatatat ctcttcatta gatgttcggg ttctaggtgt ggcaggcggt
     4081 tcgatggtac gggctaatca gtcaggaatc atcgatgtcg gtccacgttc tgcacatatt
     4141 gccggtctag attatgcagt atttacggag acagaaaaaa tcaaaggtcc taaggttgaa
     4201 tttttctctc ctaaagaagg agaccctgct gattacgtca aggtagtgat ggaagacgga
     4261 gaagaagtga ctattacaaa tacatgtgca gccaatgtcc ttggattagt gcaagaagaa
     4321 catttttctt atggaaatgt cccatctgca cgaaaagcca tccaagcatt agctgattat
     4381 tgtcatacga cggttgaaga catcgcagaa cagatcatgg aaaaatccta tgctaagatt
     4441 gaaccggtga ttttagaatt ggcagacaag tatcacttgg agaaagatca gatttctctt
     4501 gtaggtgtag ggggcggcgc tgcctcattg attacttact ttagtaataa aatgggtgtg
     4561 aaatattcga ttcctgaaaa cgccgaagtg atttcttcta ttggtgtagc acttgcaatg
     4621 gtccgagatg ttgtagaacg tatcatccct tcgccaagta aagaagatat acgatcgttg
     4681 aaaaatgaag cgatgaataa agcgattgaa tcaggcgcta caccagaatc gatcgaagtc
     4741 cacgtagaaa tcgatccaca gacttcaaaa gtaacggcta tcgctactgg ttctacggaa
     4801 gtgaaagcaa ccgatctaac caaggagatc acaacagaag aagcactaga gcttgctgca
     4861 gaggatatgc gattaaataa aaatgaagtt tgcttattgg aaaatacacc tttcttttat
     4921 gtatgcggcg aacagaatcg ttcaaaaaat gctggaagtc ttcggatcat cgatcaaaaa
     4981 ggatttatca aggtccaacg tggacatgct tcatgtatga aaacaactgc agccaattat
     5041 atgacagctg tcgaacaact ttgggaagat atggcagttt atcaaactga attgattgcc
     5101 cgaccagaat tttatctctg cttaggagca agagtctctg attttacagc gacggatctg
     5161 gaacaactac agcttttgat ggatctggaa gtatctacta tggaaccgga ggaagaagtg
     5221 atcgtcgttg ccggaaatat caaacaaaca taagttagaa gagttactaa acgaattaca
     5281 acagatcccc gaagaaattt ggggattcta ccagtttcgg cgagatttat tttggaaaaa
     5341 gattcctttg tccaagcaga aaattcttat acaacaatca atcgattgtg gtatcgaaac
     5401 ggcatgtagc atcaaaaaaa agtacccttt tgccgatgta ggagaaattt gtgaacaaat
     5461 ggctgttcca atcgtttcct gtgaatcaga gcaaataaac gaacgaatca cttttgcaac
     5521 ttatgcagaa gatgaaggga ttcgattgat gacggagccg ttagaaaaat taaaatgttc
     5581 aggactagct tcgatctcta aagaaacagc gcaagctttg attattggac atgaactatt
     5641 tcaccacatc gaagcttctg ttaagggaat ttatacgcaa agcgaaaaaa ttgtgctgtg
     5701 gcggttgcct ttttatacac atcaatcaaa cattcgtgca ttgagcgaga tagcagcgat
     5761 gagtttttca aaagagatga atcaaagcga tttttcgcct tatgtattag aggcagtctt
     5821 actttggcca tataatgaaa ttcgtagcca agggatctta gaagaaataa aaaaaataga
     5881 aaaaagatgt acggagtatg atttagatta caaataaaga gactgtgaca aaagtcgtgt
     5941 cacagtcctt tttttccgaa taaacgatgt tctcctgtca actcctcggt cacaagtcaa
     6001 aatattcaac aaacatgaga agctgttttt tgaaattgtt ccttgtgact cggagatgaa
     6061 cggcaggctc acgacctctt ggaaaacggt gttcaaaagc ttgcatctgc ggtaataagt
     6121 ccagccaagt taaaaacata agaagctatt tttacttggc tgttcttatt acttgatgca
     6181 gggcagcttt ttcacaacct ctcaataaac ggtgtgcaat cagctgaccc tcggtattag
     6241 ctcaaaaaaa acggcaaaat atgaggaact attttgccgt ttctttctct aatactcagg
     6301 tcaaaacgct gattccaaaa cctcttattt gatgggtctg tcctgaatat cttcaaaata
     6361 atcggggtaa ttatgaatca cgtattcttg ctcctcgata atcatatgta aatgcatcgt
     6421 gcaaagaaat ccgacttcat caaagttatg atcaatcatt gattgaagca ttgtctgatg
     6481 ttcatctaat actcgacccc agtctaattc tgaaatcgtc aaacgtaacc atctgaaacg
     6541 gttcaagtgc gtactataac tttctagcca atcccaaatt tctcgttttc cagcaatttc
     6601 ataacaagtt cggtgaaaat cagtatccaa atcaaaaaaa gcttttttat tttgagcgat
     6661 tactgcctga tcggtttgtt ctagtatttt ttctagttta gcttgatctt gcttggtcat
     6721 tttcgcactg cattcttgca ggatcggttt ttccaacttt tcccgcgtat aacgggctaa
     6781 tgaagcagat cggatatcga tttttgaaac ataagtgccg gactgtggaa tggtttttac
     6841 aagctcttga ttgcgcagtt ggatcagtgc ttctcgaatc ggtgtacgcc cgatagctag
     6901 ttgttcttct aacactttat cggagatttt acttccaggt gctaactcgg aataaatgat
     6961 ttgtttacgt atagattcat aagcttgctg ttgcaaatta ttgataacca tttaaccttc
     7021 ctttctatgc agatataatc tattataaca taaatcgctt acaaatcgtg tgggcataaa
     7081 aacacagtct gcaaaaaaag ccctgatagg catgcctatt agagcctcga aaagaaaaat
     7141 attgaatcaa tctggtcgta cctcttgtat cggtttgaca cgaccgccga ttcttttagc
     7201 aaaagcttcg gattcttttt tgtctttgaa aatgagcaga ttgtctaagt ttttttcccg
     7261 agtgcgacag ccagttttat cgatgtaacc gtgcattact ttaacgacat acatggggat
     7321 cacctgcttt tttcttttca ttatacgaac tactcgacac aatacaagaa aaatgcttag
     7381 acggtcttta ttaagaattt acatcatcca aagaagcgta cgcttggaat aactgatcta
     7441 actccggatt gactttgctc agcttcacta atcgttgcga atcagaaagt aaaaaacagt
     7501 gtttactact gccagtagtt tttaattttt tgtcttcagt tcccacaatt tcgtagctaa
     7561 aatccaaccg tgtccccgta tacttttgga tagttggatg gatgctcact ttttctccgt
     7621 aatggatcat ttctttatag ctgcaattta cttccagaac ggggatgatg atcccagatt
     7681 cttcgatttt tttataggga aaccctagat gtaccaataa ggctacccga gcctcttcaa
     7741 accagcggat ataattgctg tgatgaataa tccccatttg atctgtttca taataaaaag
     7801 gttctcgcac ataacctgta aatttctcca tgactcatgc ctcgttttcc attgattttt
     7861 tacaaaaata attcatccat ttcggaagtg cttcgctgat ttgtgtcggc aaaacaatat
     7921 attgttcttt tgccagctgg tctccaatga aactatgaag ataaatagct gctgcaatcg
     7981 tttggtcatt ttgaggaaac tgggctaaaa atcctgtgat catcccagct aaagtgtcac
     8041 ccatgccgcc cgttgccata gcagcagaac ctaaaggatt ggtgtagaag tgctggtgac
     8101 cataaatttt tgtctcatga cttttcaaaa cgagcacagc accgatttcc tgttgcttct
     8161 ttttgttttc tttatcccgt tgttcttgta tcggtagaga actcaaccgt tgccactcca
     8221 tttgatgagg tgtaagtaca gtttgttcgg gatagggtag caaaagatga ttagcagcaa
     8281 gtaaacttaa agcagagcca tcaatcacca gccattgttc ttttgattgg ttttctagta
     8341 cttgtttgaa acgttccaaa ctcttagaag aagtacccaa tccgggacca atcaagagta
     8401 catctgcttg ctttattacg gaaagaaact ggtcagtatc cgtccaaact acaatcattg
     8461 cttctggcag atgactgtga agagcactcc gatttttttc atcagttact acagtcgtga
     8521 gacccgctcc gctgtgtacg gcagctaaag cactcataat gattgctccg ccatattgtt
     8581 cattgccgcc aatcaaaacg atacgtccaa atgttccttt atgtgaaatt tttggacgag
     8641 gtgtgatgat tcttttcact agttgttcgt ttatcagcat ctaaaaacct ccttttactc
     8701 attatagcgt atattttttt tagagaaaaa cagataagaa aaggaattgt cagatttttt
     8761 gaactatttt tttctgtaat ttgtggtatc atgaacacga agacttaaat aagtggagga
     8821 ttaactttat gacaattgat tggcaaaaag aagtagaagc acgtaaagaa gacttgcttg
     8881 aagacttgaa aaatctttta cgtgtcaaca gcgagcgcga tgactcaaaa gtaacaccag
     8941 atgcaccatt tggacctgga cctcgcgacg cattgaaaca tatgttagct tatggcgaac
     9001 gtgatggatt taaagtaaaa aatgtcgata actatgcagg gcatattgat cttggcgaag
     9061 gagacgaaac gctagggata tttggacaca tggatgtcgt tcctgcagga gatggctggg
     9121 acacagatcc ttatgaacca gtaatcaagg atggaaagat ctttgcacgc ggatcaagcg
     9181 atgacaaagg tccaagtatg gcagcttact atgcgatgaa gatcattaaa gaacttgact
     9241 tgaaactatc aaaaaaagtt cgcttcgtag tcggcagcga tgaagaaagc ggctggggcg
     9301 atatggctta ttatttcgaa catgaagaag aaccagattt tggtttctca ccagatgctg
     9361 aattcccaat catcaatggt gaaaaaggaa atgtttcttt agctttacgc ttcaaaggcg
     9421 acaatgcagg agattatgtc ttgaaatctt ttgtttccgg acttcgcgaa aatatggtgc
     9481 caggaacagc aactgcagca cttcaagtac caagtgcaga tgcagctatc gcgatggaag
     9541 aagcatttta ccaattcatc gaagcaaatc cagtaagcgg aacgattgaa gcggacaata
     9601 cgtatgtaaa aatcgaatta gttggtaaag gcgcacatgg tgcaagccca caatctggta
     9661 tcaatgcagg ttctttcttg gcattgttct tagataacta tgaattccta ggatctgcta
     9721 aacaatttat ccatgtagca gctgcttatg tccatgaaga tttttatgga gaaaaactag
     9781 gagtcgctta tgaagatgaa aaaatgggca aattgacaat gaatgctgga ctatttgctt
     9841 ttgaagaaaa tggtacagag gaagcgaact tcatcaatat gaatttccgt tttccaaaag
     9901 gtgtaacagt agacggattg caaagtgaca tcgaacaaac agtggggcaa gaaggcgcaa
     9961 cagttactcg aggtgctcgc gtaatggaac cacattacgt accaatggat gatccattgg
    10021 tggctacatt attgcaagtc tatgaagacc acactggaga aaaaggctac gaacaaatca
    10081 tcggtggcgg aacttacgga cgtttgttga aacgtggcgt tgcttatgga gcgatgttcc
    10141 caggatatac tgatacaatg catcaagcaa acgaatttat gagtcttgat gacttgttca
    10201 gagcaacagc aatctatgca gatgccatct atcgtttggc gaaataatta attaaaaaga
    10261 ggatcaagaa ttgcaaatta tttttgcagt cttgatcctt tttttacttt ctactgtggt
    10321 attcatgata aacatgatat agattcaatt catattcttt cttagcgttc gtgacgactg
    10381 tatccaaaat caaccctgtt actaatgaaa gaagtgctaa agtcatcaat ccagtactta
    10441 aaatcgcaga agggatgcgt gtaataaagc ttgtcagcat atattcgcga atcacaggaa
    10501 tccccgtgac caatccaaat aaaaagaaga agatggtcca aatcccaaag aaaagcaaag
    10561 gcttataatc tttaaacatt ttaataatca tcatgatcac tttgaatccg tcagagaatg
    10621 tattcaattt tgattcgctg ccttcaggac gatcacgata atcgattggg atttcaacga
    10681 acttgaattt tttatctaaa gcatggatcg tcaattccgt ttcgatttga aaaccagaac
    10741 tcataatagg aaaacttttg acaaagatac gattgaatcc tcgatagccg gtcatgacat
    10801 caagaatttt tgttttatac attctagtaa ttgtatttct aacaaggtta tttccaaaat
    10861 cgtggaaagg tctcttattc tcatcaaagt aggttccatt tgataggcga tcaccaatga
    10921 ccatatctgc ttcaccagaa cgtaatttct cgagcaaacc atgtacagct tctgcaggat
    10981 aagtatcatc gccatctacc attaaataat agtcggcatc gatatcaaag aacatttggc
    11041 ggatcacatt tccttttcct tgacgaggtt ctttttttac gattgctcca ccttgaacgg
    11101 ccaattcgta tgttcgatcg gtcgaattat tatcatagac ataaatatct gcttctggta
    11161 attctcgttt aaagtctgca atgactgttg aaattgttgc ttcctcattg taacaaggaa
    11221 tcagaacagc aattttttct tgttgttcca tttttcactc tccttaacta tagaaaacaa
    11281 aagctaaatt aaaaatacct cataatcaaa ggaaatgcta gtttttcccg ctaaatatca
    11341 tttatttaaa aagaaaatac tggaatatat gtttggaaag ctctatctaa aaaaccaccc
    11401 actacaaaag aaggacatga tacctctctt ttgaatagtg ggtgcgtatt cgttctctca
    11461 cttttttgac gtattaatct gttgcacctt tttttcttga aatttctaat acggttcctg
    11521 tatgagcatc tgctaaaaat tcataataaa cagtttcgcc atcttctatt cgagaaagac
    11581 ctccccgata agcactcgac cgaacggcga atttcctaat aggttccttt tcaaaagaga
    11641 tccaagaacc ttcgattgca ccttctttta gaaaagatga cttgatattt tcaagtactt
    11701 ggtctgctga caatactttt ttgcgatgat accaaatcgt tgaagctacc ccgctcaata
    11761 atcctagacc gattccaact gctaacccgc ctttaaaata gcttagttcg ctttcttcat
    11821 acatgtggac atacctcctt cttctcactt gttactcctt gtgcttattt taccacactc
    11881 tcatattttc tttgaaataa ataaccgcta ccagaaaaaa taagctataa taaatacgat
    11941 cggtctgcag aaaaaatcat attttatccg cagatcaata taagtctgag aggagtttag
    12001 tctgaaattt agacgaatag catatggaag aaaaaacatt tcaacgaatc aaagagttaa
    12061 cagaattaca aggaacaagc ggttttgaac aagatgttcg cgcttatatg gaaagtcata
    12121 tggaaccgct ggtagatgag ttacagttag atggtttggg cggcattttt ggtctgcgcc
    12181 atcatgaaga agcggatgca ccccgtgtaa tggtcgcagc acatatggat gaagtcggat
    12241 tcatgctgac acaaatccaa gaaaacgggc tttttaaagt cgtacctcta ggcggctgga
    12301 atccttacgt tgtttctgct cagcgtttta cacttaaaac ctctactggt aagaattatc
    12361 catgtatttc ttcttccgtt cccccacatt tattgcgagg aacaagcgga caaaaatcag
    12421 tagaagtaac cgatattttg ttcgatgctg ggtttgaatc aagagaagag gcaatgagtt
    12481 acggtgtcct tccaggagac acaatcgttc cttacgctga aacgatcaaa acagccaacg
    12541 gaaagaatat tatcagtaaa tcatgggaca accgctatgg ctgtacaatg gtattagaag
    12601 ctttagaagc gttgcaaaat gaaacattag gtcatacatt gattgcaggc gcgaatgtcc
    12661 aggaagaagt aggcttgcgt ggttctaaag cttctgtcaa taaattcaag ccagatctgt
    12721 tctttgcagt agactgctct gcagcagatg atacagtgac gaaaaatggc acattcggac
    12781 atttaggaga aggtacattg atgcgtatcc aagatccagg tttgatcatg cttcctcgtt
    12841 tgcgcgagta cttgctggat atcgctgaaa caaacaatat cccttatcaa tactttgttt
    12901 caaaaggcgg tacagatgca ggtgctgctc atacacaaaa cgaaggaatc ccaagtacag
    12961 tgattggcgt agtgggacgt tatatccata cgcatcaaac gatgttcagt attcgcgatt
    13021 ttgaagctgc acgagaaatg ttgattcaaa cactgaaagg tttggataaa tcaacagtga
    13081 atacgatcgt atacggaaaa taatgcgata gtgaaactat aaaatctggc aaaagattgc
    13141 tttttgccag atttttttta taaaaagagg atcaatgttt gttagttcga aagaaaggtg
    13201 tataatttaa ttgaaaaata cataaacaga aagtagagga caaagaatga ttatcccaaa
    13261 tagtttagaa gaattagcag gctacgtaga aactggaaag agtgtatttt tctttactgc
    13321 cggctggtgc ggagactgcc gttttatcaa accgcaaatg cctgaaattg aaaatgactt
    13381 ttctgattgg caatttattg aagtagaccg tgacaagtac atagatgtag ccgctgaatg
    13441 gaacattttt ggtatcccaa gttttgtcgt gatccaagac ggaaaagaat taggtcgtct
    13501 agtgaataaa gatcgtaaaa caaaacagga aatcgaatcg ttcctagaaa gtgtaacaaa
    13561 aggctgacat ctgttaggag gggtcaagat gaatcaagaa tataagaata ttttagtagg
    13621 tatcgacggt agtgaacaag cacttgctgc tttcaaaaaa gcggtagaag tggctcgccg
    13681 taataatggg aaagtatatg tagcaaacgt aatcgatcag caattttata actttatggg
    13741 ctatgcacct attgatcaaa atctagtcga tcagcaaact gaaacagcca aggaaatgat
    13801 cgaagaatgt aaagaatatg ggaaatctgt tgattacaca aatatagaag gaattattgc
    13861 atatggttct gttcgtgaat ccatggcagt caaattgcca aaaaaatatg agatcgatct
    13921 aatcatggtt gggcagtcag gtctaaatgc agtcgaacgc tttatgacag gaagtgtagc
    13981 cagctacgtg atacgtcatt caccttgtga tgtcttgatc gtttctgacg aagaagaaca
    14041 gccaagtaat taagcaagtg gaacttgtac gaccttttta atcaattaac taaaacagta
    14101 aagggactgt gacaaaagtc ttgtcacagt cccttgttac gaataaatgg tgttccagaa
    14161 gaggcttctt cggaaataaa gcatgaaaaa aatttcatgc agtgaatgca attttttgtt
    14221 aagataaatc tcagcaaagg ataatggagg aaagaacatg atttttgctt ataacaaagc
    14281 acacgtcgga gacaccttga tggttattat agccgacgat aaaggaacag aaaacactgt
    14341 tgaacgcaaa tggaatgttg ctcggatcaa agatgaacaa ggtcaagttg ttgcttggaa
    14401 ctttttccat atctccgatc atctaacaat cgaagggaac ggccaagtaa gcttaacaga
    14461 tgaggaatta gcgaaattga atcgattgat caaagaagca ggattcgaag aacagcttga
    14521 agctgatcat gaaccgaaga tcgttgtcgg gtacgtaaaa acatgcgtcc cacatcctga
    14581 ttctgaccat ttatcgatta ctgagacaga agtagacaat ggtacagtat tgcaaatcgt
    14641 ttgcggtgca cccaatatcg aagctggaca aaaagttgtc gttgcaaaac caggagctat
    14701 gatgccagat ggaatgatga tctggccagg aactttgcga ggggtagata gctatggaat
    14761 gatctgttcc gctcgtgaat tgcatttgcc aaatgctcca gcaaaaaaag gaatcttagt
    14821 attgcctgag gatgccgtag tcggagaagc atttccaaaa taaagaggtt gtgacaagtc
    14881 tttgtcacaa cctctttttt a
//
LOCUS       DARPZF010000060        14625 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.063, whole genome shotgun sequence.
ACCESSION   DARPZF010000060 DARPZF010000000
VERSION     DARPZF010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.063"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            4..816
                     /locus_tag="SLE65_002329"
     CDS             4..816
                     /locus_tag="SLE65_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEI8449592.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            813..1613
                     /locus_tag="SLE65_002330"
     CDS             813..1613
                     /locus_tag="SLE65_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEI8449593.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1774..3042
                     /gene="rseP"
                     /locus_tag="SLE65_002331"
     CDS             1774..3042
                     /gene="rseP"
                     /locus_tag="SLE65_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEI8449594.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3110..4819
                     /locus_tag="SLE65_002332"
     CDS             3110..4819
                     /locus_tag="SLE65_002332"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEI8449595.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5031..9389
                     /locus_tag="SLE65_002333"
     CDS             5031..9389
                     /locus_tag="SLE65_002333"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEI8449596.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9534..10007
                     /gene="rimP"
                     /locus_tag="SLE65_002334"
     CDS             9534..10007
                     /gene="rimP"
                     /locus_tag="SLE65_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEI8449597.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10030..11205
                     /gene="nusA"
                     /locus_tag="SLE65_002335"
     CDS             10030..11205
                     /gene="nusA"
                     /locus_tag="SLE65_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEI8449598.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11227..11520
                     /locus_tag="SLE65_002336"
     CDS             11227..11520
                     /locus_tag="SLE65_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEI8449599.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11517..11828
                     /locus_tag="SLE65_002337"
     CDS             11517..11828
                     /locus_tag="SLE65_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEI8449600.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11841..14147
                     /gene="infB"
                     /locus_tag="SLE65_002338"
     CDS             11841..14147
                     /gene="infB"
                     /locus_tag="SLE65_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEI8449601.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14174..14521
                     /gene="rbfA"
                     /locus_tag="SLE65_002339"
     CDS             14174..14521
                     /gene="rbfA"
                     /locus_tag="SLE65_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEI8449602.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
BASE COUNT         4983 a         2598 c         3255 g         3789 t
ORIGIN      
        1 agaatgttac gtttttttcc gcaaaaaaac aaatatattc aagaaaaaag cgaatttcaa
       61 tttaataccg atggaccaat tcctcagcac attgccatca tcatggacgg caatggtcgt
      121 tgggcgcaaa accgtcgttt gccacgagtt gctggccata aagaaggcat ggaaacagta
      181 aagaaagtca caaaaaaagc atcaaggctt ggagtgaaag tgttgacgct ttatgccttt
      241 tcgactgaaa actggaagcg accaaaagat gaagtaagtt ttctcatgca actacctgtc
      301 gacttctttg atacgttcgt accagaattg attaaagaaa atgtcaaagt tcatgtcatg
      361 ggttatgaaa acgtattgcc agaacatacg caagatgctg taagacgtgc aattgagcaa
      421 acaaaaaaca atactggaat ggtattgaat tttgctttga attatggaag tagagcagag
      481 atcgtgactg ctgtccaaga aattgccgaa gaagtagcaa aaggagaaat acacgcagaa
      541 gaaatcgatg atgaattgat tgctaagcat ttaatgacag gtttcttgcc taaagagtta
      601 caagatcctg agctgatgat ccgtacaagt ggagaagagc gaattagtaa ttttctgtta
      661 tggcagatcg catatagtga gctgtatttt acaaaagcgc tttggcctga ttttgatggt
      721 gcgcatcttg aagaagcaat cgcctcttat caaaatcgag accgtcgatt cggcggtgta
      781 aaaaaaacag aagatgagaa aggggatcag tcatgaaaca acgtgtgatc acagcagctg
      841 tggcgctagt cttgtttatt ccgattatat ggatcggagg catagcggtt gagcttacag
      901 cagcaatctt agcggtagta ggagtttacg agctgttccg gatgaaagga ttgacactct
      961 taagttttga aggagtttta tccgccgttg gtgcagtgtt acttgttttg ccaaaagaaa
     1021 gatggttttt ctttcttcca gagaatgtaa gtacatttat gttattttat cttatagtta
     1081 tgattctttt aggaacatca gttatttcta aaaatacgta tacgattgat gaagcaggtt
     1141 ttcctgtgct tgtcagcttg tatgtgggaa taggtttcca gaattttgtc aatgcacgaa
     1201 cagaaagctt ggctgttttg atatttggtc tatttattgt ttgggcaact gatatcggag
     1261 catatatggt tggtcgacgt tatggtcagc ataagttaag tcctgatatt tcgcccaaca
     1321 aaacgattga aggtgcgctc ggtggtatcg gtagtgctgt tgtagtcgca tttctttatt
     1381 tattgctata cccagcaaaa gaactattca atcatggtat gtttgtcatg cttctgatga
     1441 cgattatttt ttcagcagtc ggacaatttg gtgatttggt cgaatctgca atcaaacgtc
     1501 attatgatgt gaaagactcg ggaaatatct taccaggcca tggtggaatc ttagaccgtt
     1561 tcgacagttt gctgtttgta tttcctatca tgcatttatt tggcattatt tagtaagtat
     1621 acctgcgttt ctttgtgaat ttcataaaag acgcaggttt ttatttttca ttatattgat
     1681 actattggtg tctttggtat actatggtaa aattatagtg ttttatcgtt gttttataaa
     1741 aaacacaaaa aacaagtaaa ggagaaaaaa gctatgaaaa cgattctgac atttatcatc
     1801 gtttttggta tattagtgat tgttcatgag tttggtcatt tcttctttgc gaaacgatca
     1861 ggaatcctcg tccgcgaatt tgctatcggt atgggtccga aaatttatgg gcatcaagca
     1921 aaagacggga caacatatac gcttcgccta ttacctattg gcggttatgt tcgaatggca
     1981 ggcaatgggg atgatgaaac agaaatggca ccaggaatgc ctctttctct tttactaaat
     2041 tctgacggca tcgtagagaa gataaattta agtaagaaaa tccaattgac aaatgctatc
     2101 ccgatggaat tgagccgtta tgatttagaa gatgagctga ctatcactgg ttatgtgaat
     2161 ggagacgaaa cagaagtagt aacctaccct gttgatcacg atgcgacgat tattgaaaac
     2221 gacggaacag aaatcagaat tgcgccaaaa gacgtacagt tccaatcggc taaattgtgg
     2281 cagcgtatgc tgaccaactt tgctggaccc atgaataact ttattttggc aatcgtgtta
     2341 ttcatcattc tggcatttat gcaaggtggt gttcaagtga cgaacactaa tcgcgtagga
     2401 gagatcatgc ctaatggagc tgcggcagaa gcaggcttaa aagaaaatga tgaggtagtc
     2461 agtgtggacg gaaaagaaat ccattcatgg aatgatctga caacagtcat tacgaaaaat
     2521 ccaggtaaaa cattagactt taagatcgaa cgagaaggtc aggtgcaatc tgtcgacgtg
     2581 acaccgaaat ctgtagagtc aaatggcgaa aaagttggcc aacttggtat aaaagcccca
     2641 atgaatacag gttttatgga taagatcatt ggagggacgc gtcaagcttt cagcggttca
     2701 ttggaaattt tcaaagcctt aggatcacta tttacaggtt tcagtttaga taaattaggc
     2761 ggacctgtca tgatgtacca attgtcttca gaagcagcaa atcaaggtgt aacaactgtt
     2821 attagtttga tggcgcttct ttcaatgaat ctcggaatcg tcaatctgct tccgattcct
     2881 gccttagatg gcgggaaatt agtcttgaat atttttgaag ggattcgcgg gaaaccatta
     2941 agtcaagaaa aagaaggaat attgacatta gctggctttg gatttttaat gttgttgatg
     3001 gtgctagtta catggaacga tattcaacga ttctttttct agaaaaagtt gacaaatagg
     3061 gtataataac aaacgataac tattttgagg aaataaagga gtatatagaa tgagacaatc
     3121 aaaaatgttg attccaacat tacgcgaagt tccaaatgat gcagaagtat taagccatca
     3181 aatcttgcta agagctggat atatccgcca agtatcagcg ggtatttatt catatctgcc
     3241 attagcaaat cgtgtattgg aaaaactgaa acgcattatg cgggaagaat ttgaaaaaat
     3301 cggagcggta gaaatgctga tgcctgccat cttgccagca gaactttggg aagaatccgg
     3361 gcgttacgaa acatatggac caaacttgta tcgtttcaaa gaccgcaatg atcgaaaaat
     3421 gatccttgga ccaactcacg aagaaacttt tactgatttg atgcgtaatg aaatcaattc
     3481 atataagaaa ttacctttaa atctttatca aatccaacct aaatatcgtg acgaaaaacg
     3541 acctcgcttc ggtttgcttc gcggaagaga gtttatcatg aaagatgcat attctttcca
     3601 tgcaacggaa gaaagtttgg acgagacata taaagattac gaaaaagcct ataccgaagt
     3661 attcaagcgt tgtggcttag aatttcgctc gatcatcgga gacggcggcg caatgggcgg
     3721 gaaagactca aaggaattca tggcgatctc agaaatcggg gaggatacga tctgttattc
     3781 gactgaaagt gattatgctg caaacttgga gatggctaca agctactatg tatcaaaaaa
     3841 atcgcatgaa acacagcttg aattggagaa agtagctaca cctaacgtaa aatcaattga
     3901 cgaagtagca gatttctttt ctgttgaacc tcaaaaaatc atcaagtctg tattgttcat
     3961 tgcggatgaa caacctgtcc ttgttttggt acgtggagac catgaagtca atgacgtaaa
     4021 actgaaaaac tttttatctg ctgacttttt agaagaagca acagaagaag aagcacaaaa
     4081 atatctaggt gctgagtttg gttctgtcgg accagtcggt gtttcagatg acgtaaaagt
     4141 atatgcagac cgttatgtcc aagatttagc gaatgccatt actggagcga acgaaacagg
     4201 attccactat aaaaatgtga atccagaacg cgatttcact gtgctttctt atgaagatct
     4261 tcgttttgta caagaaggag atccttcacc agacaacaac ggtgttcttg cctttactcg
     4321 aggaatcgaa atcggacata tattcaaaat cggcactcgt tacagtgaat ctatgggagc
     4381 aactgtacta gacgaaaatg gacgagaaaa atttgtgatt atgggctgtt atggtatcgg
     4441 tgtaagtcgt ttattatcag caatcgtaga acaacattca gatgaacaag gaatcaattg
     4501 gccaaaagga attgcgccat ttgatctgca tatcgtccaa atgaatctaa aagacgaata
     4561 ccaaacaagc ctgacgaatg aactagaaga agcgatgaca aaagctggct atgaagtact
     4621 ggttgatgac agaaatgaac gcgcaggagt gaaattcgcg gattctgatt tgattggctg
     4681 tccaatcaga atcactgtcg gtaaaaaagc agtggatgga atcgtagaag tgaaaatcaa
     4741 gaaaactggc gaaatggttg aagtacgtaa agaagaattg gcgaatactt taccaatcct
     4801 cttgaaccaa ggcgaataat aagcgttaaa acacagaaaa taaaaatagc tgaatcagct
     4861 gtttttgaca atctgatgat tcgcttttaa aattggaact gcgatttgaa tcgcagttcc
     4921 aattttttaa tgtaaaactc agaaaaaacg agtatactaa aaggtactga aaaagaagag
     4981 gataagatgc gatcaattgc attgtttctc atcagaaagg gcgtatatct ttgtcagaaa
     5041 aacgagattt atttgaaaaa ctgttggaac aaatccaact agaggaagca gaaaaaaatc
     5101 atccactgct tactgctggt gaaatggata gtgtagtggt ccatcgtaaa tcgcgtttat
     5161 gggaatttac gctacatttt tccaaaattt tgcctattat gctatatcgg tcattgactc
     5221 agcatctgac tatcgctttt aaagatattg cacaagtcaa actgaatatc ttagcagatg
     5281 accagacatt cgatgaacag ctcttgcaag attactgggc ccaagctttg gaaaatcagc
     5341 aatgcgatac accactagca cagcaagtat tgaaaacgca ggtacctgtg ataaaagatc
     5401 gtaaagtcat cttgccaatc gacagtacag gagctatttc ttatttgaag caacaatact
     5461 tgccattagt agaagagttg ttcgtcagtt acggattccc aaaatttcgt atcgaaccag
     5521 aagtggatga gcagcaagcg gaacgagtat tgaaactttt tgaagaacgc aaacaagaac
     5581 aggcagaagc ctttatgaag caagcagctg aaagtctagt tgtccacgaa caaaagaaaa
     5641 aggaaagaaa agagcaatcg ccagctcttg aaggacccat ccacatccag ctaggacgaa
     5701 atattccagc cgatgaacca acgacaccaa tgatcagtat cgttgaagaa gaacgaagag
     5761 tcacacttga ggggtacgta ttcgacaaag aagtcagaga actacgttca aaacgcaaga
     5821 tcttgacttt gaaaatcaca gattatactt catcatttat cgtcaaaaaa ttctcgaacg
     5881 gcgaaaaaga tgaacaagta tttgatgcga tcagtgtcgg tagctggtta aaggtacgag
     5941 gaagtattca agaagatacg tttgtccgtg atttggtcat gaatgcgcaa gatatcatag
     6001 aagtcaaaca tacacctcgc aaagattatg ctcctgaagg ggaaaaacga gtagagcttc
     6061 atgttcatag caatatgagt acgatggatg caacaaacag catctctgat cttgtggcac
     6121 aagcagggaa atggggacac cgagctatcg ccattacaga ccacggtggt gcgcaagcct
     6181 ttccggaagc acatagtgct ggaaaaaaag caggtgtgaa aatcttatac ggcgtggaag
     6241 cgaatgtcgt agatgatggt gtcccaattg cttataatga tgcacatgaa gcattgagtg
     6301 aagccacata tgtcgtattt gacgtggaaa cgacaggatt gtctgcagta tatgacacga
     6361 tcatcgagct agccgcagtc aaaatgtata aaggaaatgt gatcgaaagc tttgatgaat
     6421 ttatcgatcc aggacatcct ttgtcacgaa caacggtaga tctgactggt atcacggatg
     6481 gaatggttcg aggatcaaag tcggaagaag aagtattgcg gatgttcctt gaattttcaa
     6541 aagatacaat tttggtagcc cacaacgcgg cttttgatat ggggttcttg aatactagct
     6601 acgcaaggta tggtattcct gaagcggcca atccagtcat tgatacgttg gaattagcta
     6661 gatatctgta tcctcaattc aaacgtttcg gattaggtgt gttatctaaa aaatttggtg
     6721 tcagcttgga acagcatcac cgagcaatct atgatgctga agcaactggt cacttagcat
     6781 ggatctttgt gaaagaggca atggacaatc ataacatgct ttatcatgat cagctaaatg
     6841 agcatatcgg agaaggagat tcttacaaaa gggctcgacc tttccatgta acgattttag
     6901 caaaaaatca ggcaggactg aaagatttgt tcaaactgat ttcaatgtcg aatgtcgaat
     6961 acttcgaacg cgtcccacga ataccacgct cccaattgaa aaagatgcgt gaaaatctat
     7021 tgatcggctc agcttgtgat aagggagaaa tattcgaagc catgatgcaa aaaggggtag
     7081 aagaggcaag aaaccgagca aaattctacg attatattga agttatgcca aaagcggtct
     7141 atgcgccttt gatcgagcaa gaattggtaa aaaatgaaca tgatttggaa gaaattatcc
     7201 aaaatttggt agaaatcgga aaaagtttgg ataaaatcgt tgttgcaaca ggtaatgtac
     7261 attatctgaa cgaagaagat gccatttacc gaaaaatttt gatcaattct atgggcggag
     7321 cgaatccgtt gaatcgtcat agtttgccgg atgtccattt ccgaacaacc gatgagatgc
     7381 taactgcatt tcacttttta ggggaagaaa cagcgaaaga gatcgtagta gaaaatacga
     7441 ataaaatcgc agatatctgc gaagaagtga ttccagtcaa agatgaactt tatacaccga
     7501 agattccagg ttcagaagat gaaatatcag aattgagtta cacaaaagca aaacaaatgt
     7561 acggagatcc gttacctgag atcattcaaa aacgattaaa aaaagagttg aattctatta
     7621 atggtaatgg cttctcggtt atttatctga tcgcccaaaa actagtgcat aaaagtaatg
     7681 aagatggcta tctagtaggt tcacgtggct ctgttggctc tagctttgtt gcgacgatga
     7741 caggaatcac tgaagttaat ccgttagccc ctcattatta ttgtccagag tgccaatatt
     7801 ccgagttttt tgaagatggt acgtatggtt ctggatttga catgccagaa aaacaatgtc
     7861 caaaatgtgg tgcacgctta aacaaagacg gtcatgatat tccatttgag acatttttag
     7921 gattccatgg agacaaagtg cccgatattg atttgaactt ctcaggtgat tatcaagcag
     7981 aagcccataa ctatacgaaa gtattgtttg gcgaagacta tgtttaccgt gccggaacga
     8041 ttggtacagt cgccgacaaa acagcatatg gctatgtaaa aggatacgaa agggacaata
     8101 atctgcagtt tcgaagtgca gaagtcgaca gattagcaaa aggcgctact ggagtcaaac
     8161 ggacaaccgg ccagcatcca ggggggatca tcgttattcc cgattatatg gatgtctatg
     8221 attttacgcc gatccaatat ccagcagacg atcaaaattc ggaatggaaa acgactcatt
     8281 ttgattttca ctcgattcac gataatgtat tgaaattaga tattctaggg catgatgacc
     8341 caactgttat tcggatgctt caagatttat cagggatcga tccacaaacg atccctacgg
     8401 atgacccgga agtgatgcgg atatttgccg gtcctgaagt acttggagta agtcaggaac
     8461 aaatttattc caaaacaggg acattaggta ttccagaatt cggcactcgt tttgttcgag
     8521 ggatgctaga agaaacgcat cctacaactt ttgcagaact actgcaaatt tccggactat
     8581 ctcatggtac agacgtatgg ttaggaaatg cggaagaatt gattcgacga ggagatgcga
     8641 cactggcgga agtaatcggc tgtcgtgatg atattatggt ttatttgatc catgctggat
     8701 tagatagcgg gatggcattt aaaatcatgg aaactgttcg taaaggacaa tggaacaaga
     8761 tccctgatga attgcgagaa acctatctat cggcgatgaa agaaaataat gtgcccgact
     8821 ggtatatcga ttcttgttca aaaatcaaat atatgtttcc gaaagcccat gctgcagctt
     8881 acgtattgat ggctcttcgt gtcgcttatt tcaaggttta tttccctatt ttgtattact
     8941 gtgcatactt ttctgtacgt gcagacgact ttgatctagt ctccatgtgc aaaggaaaag
     9001 atgctgtgaa acaagcaatg aaagaaatca cggacaaagg attagatgct tccgtaaaag
     9061 aaaagaatca actgacagtg ctggagttag ccaatgaaat gctggaacga ggattcaaat
     9121 ttggaatgat tgatttgtat aaatcggatg ccgttaactt tgttattgaa ggtgatacgt
     9181 tgatcgcacc atttagagct gtcccaagtt tgggaaccaa cgtggcaaaa caaatcgttg
     9241 aagcaagaaa agacggtcca tttttatcca aagaagatct tgccacccgc ggtaaagttt
     9301 caaaaacatt gatcgaatat atgaacgaca atggcgtatt gaaagatcta ccagatgaaa
     9361 atcaattatc gttattcgat atgctataag catctgtttt cctgtctgct tgtaatttta
     9421 agcagagtat ggtatagttc ttataggtaa tgatactaac tgtgagtgag cggatttttc
     9481 gctcactctt tttaatggaa ttacgcactt aattttttaa ggaggcgaaa cttttgagta
     9541 gcgtcgttga aacagtcaca gaaatggtga caccgatttt agatgaacaa aattttgaac
     9601 ttgtcgaagt cgaatttgta aaagaaggaa aaagctggtt cttacgagta tttattgaca
     9661 aagaaggcgg tatcgatatc gaagaatgcg cctttgtcag tgagaaactg agtgaaaaac
     9721 ttgatgcagc agatccagat ccgattcctc aagcttattt cctggaggta tcctccccgg
     9781 gagcagagcg gccattgaaa aaagaaagcg actatgaaaa ggcacttggt gattatgtcc
     9841 atgtctcctt ataccaacca gtagatggcg aaaaacaata tgaaggattt cttcaatcat
     9901 ttgatgctga acagcttaca ttgaaaatac gcataaaaac acgagaaaaa gaattgactt
     9961 ttgaccgaaa aaatattgca aaagctcgct tagctatcca attttaatca cggagaggaa
    10021 tcagaaaaaa tgagtaaaga aatgttaaat gcgttagacg ctttagaagc tgaaaaaggg
    10081 atctcaaaag aaatcgtgat cgatgcttta gaagcagcat tggtttctgc atacaaacgt
    10141 cactatggcc aagcacaaaa cgtcgaagtg gaatttgatc agaaaaaagg aaagatccat
    10201 gtctatgcgg taaaagaagt aacggaagaa gtgatggatt cacagttgga agtctcattg
    10261 aaagatgcac ttttaatcaa tccagcatat gagatcggtg atacgatccg ttttgaagta
    10321 acaccaaaag attttgggcg gatcgctgcg caaacggcta aacaagttat tttacagcgt
    10381 gtacgtgaag cagaaagaac gattatttat aacgaattca gtgcttatga aaaagacatc
    10441 atgcaaggaa tcgtcgaacg ccaggataaa cgttatattt atgtcaatct tggtaaaatt
    10501 gaggcagttc tttctaaaca agatcaaatg ccaaatgaat tttatcaacc acatgatcga
    10561 atcaaagttt atgtttcccg agtagaaaat acgtctaaag gtccgcaagt atttgttagc
    10621 cgcagccatc cagacctatt gcgccgctta tttgagcaag aagtaccaga agtctatgat
    10681 ggaatcgttg aaattgtcag catcgcccgt gaagctggcg atcgttcaaa agtggcagtt
    10741 cgctcaaatg atccaaatat cgatgcagtc ggtacatgtg tcgggccaaa gggacaacga
    10801 gttcaagcaa tcgtcaatga attaaaaggc gaaaacatgg atatcgtcga atggaatgaa
    10861 gatccagctg tattcattgc aaatgcattg aatcctgcac aagtcatgga tgtgatcttc
    10921 gatgagacaa atccaaaggc ctgcacagtt gtcgttccag actaccaatt atcgctagca
    10981 atcggtaaac gcggacaaaa cgcacgttta gctgctaaat tgactaacca taaaatcgat
    11041 atcaaatcag aatctgacat gacggaattt tatgaaaatc aagaacaaca aaaagaaaca
    11101 gaagaactgc atgatgaagc aatcgttcag tcagatttaa cagacgatga atatgaaaca
    11161 attgcattca acaatgaaac ggtcgaagaa aaaccagaag cttaacttta gtaaggaggc
    11221 aaagagatga aacaaaggaa aattccttta cgcaaatccg tggtttcagg tgaaatgaaa
    11281 cctaaaaaag agatggtccg aatcacccgt tcaaaagaag gggaagtatc gatcgatcca
    11341 actggaaaaa tgcctggacg aggagcgtat gtctcacttg agccggaaga agtacaacaa
    11401 gcttgggata aaaaaattct cgatcgagta ctcgaaacaa cattaacaga tgagttttat
    11461 caagaacttc ttgactatgt cactcaccaa aaagcacgta aagagttatt tggaaaatga
    11521 atacagttaa tcggcaaaaa gccatgaatc tcatcggtct agcgatgcgc gcgggaaaac
    11581 taatcacggg tgaagaactg accattgctg aaatccgcaa acaaaaagca aaattggtgt
    11641 ttgtggcaac cgatgcaagc gagaatacaa gaaaaaagat aaaagataag agttcatatt
    11701 atgaagttcc ttgctttgag ctattttctg aagcagaaat cacgcagatg atcggaaaac
    11761 ctcgcaaggt attcggaata atggatgccg gatttgcgaa gaagaccaag gagctaattg
    11821 aaggttagga aggtgattgc atgggcaaca aaagaatcta tgaattagca aaagaactca
    11881 aaaaatctag taaagacgtc gtggaaaaag cacaacaact tggcatcgat gtgaaaaacc
    11941 atatgggtgc gattactagc aatgatgaga agaaattgca acaagcgttc aaaaacccaa
    12001 gcacgaaaca acaagctgca caacaagcaa gcagaaaacc agccaatcaa cagccgaacg
    12061 atcaacgtaa aaaagaaaca acgaacaatc aacaaaaaaa taaaaataac cgcagttatc
    12121 aagatcgcgg tcaagggagc ggtcaagtga atcaaggaaa aaaaccaaca acaaaccaaa
    12181 ataatacggg aaataccagc agccaaaatc gtcaaggaac gagccaaggc ggcaatcaaa
    12241 accgtactaa caataacaac aaaccaaaca ataacaatcg cggcaaattt aataataata
    12301 accgtaatcg ttataataaa aaaggtaaaa aaggcaaaca gcaacaatca actaaaccag
    12361 ctgtaccacc acgcaaattc cgtgaattgc cagatgtatt agagtatact gaaggtatga
    12421 acgtagcaga tattgcgaaa aaaattcatc gtgagccagc agaaatcatt aaaaaattat
    12481 ttatgcttgg tgtcatggtc aatcaaaacc aagcactgga taaagatacg attgaactgt
    12541 tagcgacgga ctatggcatg gaaccacaag aaaaagtcca agttgacatt gctgatatcg
    12601 ataaattctt cgaggcagaa gaagtcgatc cagataaatt agtctcacgt ccgccagtcg
    12661 taacgattat gggacacgta gaccatggga aaacaacttt attggataca ttacgccatt
    12721 cacgtgtaac aagcggcgaa gccggcggaa tcacacagca tatcggtgcc taccagatcg
    12781 atattgatgg taaaccaatc actttcttgg atacaccagg acatgcggcc tttacaagta
    12841 tgcgtgcacg tggagcaagt atcacagata tcacgatctt agttgttgct gcagatgatg
    12901 gcgtcatgcc acaaacagtt gaagcaatca accatgccaa agctgcaggc gttccaatca
    12961 tcgtcgctgt aaataaaatt gataaaccag gtgcaaaccc tcaacatgtt atgcaagaat
    13021 taagtgagta tgagttaatt cctgaagcat ggggtggaga aacgatcttt gttgagatct
    13081 cagcgaaatt cggccaaaac atcgaagaat tgctggaaat gatcctgtta gtcgcagaag
    13141 tagaagattt aaaagcagat ccaacacaac gcgcaatcgg aacagtgatc gaagcacgtc
    13201 ttgataaagg taaaggtcct gtgtcaacct tacttgtcca agaaggaaca cttcatgttg
    13261 gtgacccaat cgttgtcggt aatacttacg gacgtgtccg tgtaatgaca aacgatcttg
    13321 gccgtcgcga taaagaagca ggacctgcaa cgccagtaga aatcactggc ttgaatgatg
    13381 tacctcaagc aggtgaccgt ttcgtagtct tcgaagacga aaagacagca cgtgcagcgg
    13441 gtgaagaacg cgcgaaacgt gcattattag aaaaccgtgc tgccacaagc cgtgtgactt
    13501 tggataactt atttgaaagc ctgaaagaag gcgaattgaa agaagttaac gtaatcatca
    13561 aagcagatgt acaaggttca gcagaagcac tggctgcatc attgaagaag attgatgtgg
    13621 aaggtgtccg tgtaaaaatc gtccattcag ctgtcggagc aatcaatgaa agtgatgtaa
    13681 ccttagcagc agccagcaac gctattatca tcggtttcaa cgttcgtcct acaccgcagg
    13741 caaaagtgca agctgatact gaagaagtcg atattcgtct tcaccgtatc atctataaag
    13801 ccatcgaaga aatcgaaact gcgatgaaag ggatgctaga ccctgaattt gaagaaaaaa
    13861 tcaccggtca aatgatcgtt cgtgaaacct tcaaagtttc taaagttggt acgattgcag
    13921 gtgcctatgt aacagaagga tatattcgta gagatagcgg tgtccgtgta atccgtgacg
    13981 gaatcgtaat ctatgaaggc caacttgcaa gtctgaaacg attcaaagat gacgtgaaag
    14041 aagtcaaaat gggttatgaa tgtggtgcaa tgattgaaaa attcaatgac atcaaagtag
    14101 atgacgtaat tgaaggattt atcatggaag aagtcaaaaa tgactaaaaa ctgataaaag
    14161 gaggccaatc attatggcta actaccgtga ccgccgagtc ggtcaagaaa tcttaaaaga
    14221 agtcaatgat attttgcgca aaaaggtccg tgaccctcgt gtggagaacg taacgatcac
    14281 agatgtgaaa gttacggggg acttacagca agcaacgatc tattacagca ttttatctga
    14341 cttagcatca gataagaaaa cagcacaaga tggattgaat aaagcatcag gattgattcg
    14401 tcgagagtta gggcacaatc taagtattta taagacacct gaattgttct ttgaacttga
    14461 tgaatcagtt gtctatggca accatatcga tgaattgctt cgcgacttga acaaagacta
    14521 atcaaaaact cccgcaaatc ctgtgaaatc aggctctttg tcaataagga ctgatgagtt
    14581 gtgcaaaatc aaatctgagt cagaatgaac cacattctgg ctcag
//
LOCUS       DARPZF010000061        14554 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.064, whole genome shotgun sequence.
ACCESSION   DARPZF010000061 DARPZF010000000
VERSION     DARPZF010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14554
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.064"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            136..456
                     /locus_tag="SLE65_002340"
     CDS             136..456
                     /locus_tag="SLE65_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449603.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            908..1108
                     /locus_tag="SLE65_002341"
     CDS             908..1108
                     /locus_tag="SLE65_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEI8449604.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            1255..4044
                     /locus_tag="SLE65_002342"
     CDS             1255..4044
                     /locus_tag="SLE65_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEI8449605.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            4091..4618
                     /locus_tag="SLE65_002343"
     CDS             4091..4618
                     /locus_tag="SLE65_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEI8449606.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            4639..5829
                     /locus_tag="SLE65_002344"
     CDS             4639..5829
                     /locus_tag="SLE65_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEI8449607.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQNIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            5869..7167
                     /gene="asnS"
                     /locus_tag="SLE65_002345"
     CDS             5869..7167
                     /gene="asnS"
                     /locus_tag="SLE65_002345"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEI8449608.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            8220..8894
                     /locus_tag="SLE65_002346"
     CDS             8220..8894
                     /locus_tag="SLE65_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEI8449609.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            8891..9232
                     /locus_tag="SLE65_002347"
     CDS             8891..9232
                     /locus_tag="SLE65_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449610.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            9262..9621
                     /locus_tag="SLE65_002348"
     CDS             9262..9621
                     /locus_tag="SLE65_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HEI8449611.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            10145..12226
                     /gene="cadA"
                     /locus_tag="SLE65_002349"
     CDS             10145..12226
                     /gene="cadA"
                     /locus_tag="SLE65_002349"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEI8449612.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            12537..14003
                     /locus_tag="SLE65_002350"
     CDS             12537..14003
                     /locus_tag="SLE65_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8449613.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
BASE COUNT         4808 a         2526 c         3117 g         4103 t
ORIGIN      
        1 agaggttgtg acgtggtcac gacctctttt tgacgattat gatacaaaaa acatcattta
       61 tgaacaaaat gtgaataacg ggcgttcttg agatatgatt ttaattggga aaaacttatc
      121 gataaggagg tctttatgaa aaaaagactg ttatggtgtt tgctgtttct atccctaagt
      181 ttaacaagtc agccagtttt tgctgaagaa acacagcggt ctcctattac aggcacacgt
      241 ctgtacaaaa atgtttatgt acagacaaca gatcttgatt ctgcgattcc tgaaacagaa
      301 gaacggtctt tgcagccaag atttggttac ttttggtact gtccgacctg tgattatgaa
      361 agttgctggc atttcttaca ttctacagct gcagcttttg cttttactca tactcagaaa
      421 tatgatggac atcatcctgt tatttatgag gtatagatat gagcaaaaaa gaaaaactaa
      481 tctcgttgat cgtattggtt tgccttgttc ttctggtaac tgtcataggc tatcagaaat
      541 accatgagaa catcagacct actaaagaat cttccccagc ctcgaccgtt gaaacagaac
      601 cgataagtag tcagaaagaa taattttttt agtttaaaga agaacatcag agcaaaaaaa
      661 caccaactga acaatatgtc gtttatttta aaaaaagttc ggtttttcac tttatgtaat
      721 cgctgagaaa acttttttta ataaaaaaag tcgaaaaact ctagcttttt tgtaaacggt
      781 atgatatact ataggagtag tttttgttcg gtaatctgtg gtagcttgtt tcaaataaac
      841 atcttccaga tatacaccat tcaagtaatt gcaaaatatg tgttgataca caaggaggat
      901 ttttattatg gaaacaggta cagtaaaatg gtttaactca gaaaaaggat ttggattcat
      961 cactgcagaa aacggaaacg atgtattcgt tcatttctca gctatccaag gcgacggatt
     1021 caaaacttta gaagaaggcc aagcagtaac tttcgatgtt gaagaaggcc aacgcggacc
     1081 tcaagcaaca aacgttacta aagcttaatt aacctatact aaaaaataaa cgcccagaca
     1141 tttgcgtgtc tgggcgtttt tgtctatttt ctttaaaaag cgatgagagt atttttctgc
     1201 actttgtagt ataatttcaa aagaacatta gaggcaggag aagaggaaga tattttgaaa
     1261 ccaagaactt atgcagtcgt tgatatcgaa acgactggga cgaatccaaa agaagatcgg
     1321 atcatccaat ttggctgcgt catgattgaa tcaggtcgga tcacttcacg tttttcgatc
     1381 gatattcatc cagggcggaa gatttcaaaa caaatccagc atttaacagg gatcacgaat
     1441 caacgcgtcc aaaaagcgcc ttatttcgaa gatgtcgccc aaacgattta caatcttttg
     1501 gcagacacca tatttgtcgc gcataatatt tattttgatt ataatttttt gaaccatgaa
     1561 ctcatgcgat gcggacttcc tagtttgaag ataccaggca tcgatacagt agaacttgca
     1621 caaattttct tgccgacgga accaagcttt cgcttagctg atttgtcaga aagccttgga
     1681 tttattcatg agaatcctca tcaggcagat agtgatgccg aagtgacggg tcaacttctt
     1741 ttgctgatcg aagaacggat gagaaaattg ccaatcatca cgttagagca gattgcgcga
     1801 ttaagtagac acacaggtat ggatacgagt cgtttcattt atcatgtgat tgaagaaatg
     1861 aaagaaaaac cagagccact tgatccctca ttagaaatcg tcgatgggct agctttgcag
     1921 aaaaaagaag tggaactatt cacatccgtc cattatggcg agcggacata tccaagaaaa
     1981 aaacaagcaa aagaaaaaat gtttggtaaa acactgatgt atcgaaaaga acagaacaga
     2041 ctgatgaatg cggtctacga ccatttcaca aaagatgaat caaaagattt gatgatcgaa
     2101 gcagctacag gaatgggtaa aacaatcggt tatctgctgc cattgagtta tttggctaca
     2161 cctgaaaaac ccgctgtcat cagtaccgtt tcgctagttt tgcagcagca gatcatagaa
     2221 aaagacattc cattgctgaa tcaattgcta gatcagccca tacaacctgt aattatcaaa
     2281 agctatcgcc actatattga tttacagcgt tttaaaggca cacttgtgga accgccagaa
     2341 caaaaacaat atgctttgta tcaaatggcg gtcttagttt ggctgacgca aacgaagacc
     2401 ggtgatttgg atgaattaca tttaacaaat ttgaaccatt cattctttgc agatatcgcg
     2461 cacagaggta ttggattttt agcaagaaat cagtcatttt acgaacaaga ctttgttcgt
     2521 ttcttgcaaa agaaaatcag gcaaagtaat tttttgattg tcaatcatgc gtttttaata
     2581 caagaaacac agcgaaaaga accattgctt ccagctagtc catttttgtt gatcgatgaa
     2641 gtacatcatt tgccggaaat cgctgaaaaa gtaaatgaca aacgattaag tattaactat
     2701 ttccataaac aaatccagca attagaagaa ccaaatcagc tgtttgaccg aatacaaagc
     2761 tatttaccga aagaacatga agccttacgc tggttatcga tttatcgaga agaactttct
     2821 gcgctatgcg aagcacagat ttgtatggca gaaggattaa tgagtttagt gagcggcaag
     2881 caacctaacg gacagtatcc agaagaagtc atgatgacaa aagagatgtt ggatcagctg
     2941 ccactggaat ctgggacagc cattgatcac ctgcagcttt tttatcagga gatccagcag
     3001 ctacagtcac aaatgcgtct gacttttgag attatccaag aaagctggac aaaccagatg
     3061 cggatcgatt tagcaagttt atatagctta tttgatcaat tagacaagca gtacttgctg
     3121 atggatcaat ggctggaaga ctggcgagat catttgatcc attggttcgt tcctgggaac
     3181 acagcgcagc agatgatttt tcatctccat gattttcaag cggctatgtt gccgtcgact
     3241 gtttggtatc ctcgatatga tcgtattctt tatattggag gaacgctgaa gatcggccct
     3301 aatcgacact atctctctaa gcggcttggc attgaagcag cacctcttaa agtgattgcc
     3361 tctccttatg attatgagaa acaggcaagg atctatgtgc caaaagaggc acctgccgtc
     3421 catcaagtca gcaatcaagc atatatcgat tatttagaga cagcacttac aggtctgatc
     3481 gaacaagaag atcggccaat acttgtgtta ttcacttctc atgatgtttt gcagaaggtc
     3541 tatcagaaaa tgcatctgtc tatgctagaa aaaggacgag aaatactagc tcaagggttt
     3601 ggcggaagcc gggagaagct tttgaaacgc ttcattttgt cagaaaaaag cgtattgttt
     3661 ggcgctgaca gcttttggga aggtgtagat ttgcctgggg atgctttgca gatcgttgta
     3721 gtcacacgtt tacccttcga taatccgctt cgcccgatgg tcaaagctag gaacgcttat
     3781 ttagaatcag aggggatcaa tcctttttac caggaatccg tacctaaagc agctttgaag
     3841 ttacgccaag cattaggtcg cttgataagg acggagacag atcgtggcgt attgcttatt
     3901 ttggatcgaa gactagtcac tgcaaaatat ggtgcacgga tcatccatgc attaccgaaa
     3961 aaagtaccga tcaaagagct agctatggag gaaatctatc aggacatcca tgaattctta
     4021 aagaaaaatg aagaaggaag ttagaggagc tgtctttttt cataattaaa atctgctata
     4081 atgaaaagga atgaagataa aggagcgacg acccttgaag aaaaaacaga caaaggaaaa
     4141 aacgattaat cgcgtgttac ttggcttgat cgtattttta ttagcggtca tcgtgatcag
     4201 ctcgattttt tacttgcgtt ccagtcgtcc ggcggtgcag gcgaagaaag aagcagtaga
     4261 aatcgcaaag aaatatgcaa atcttgagga agccgatcat ttttattggt ttactcgaaa
     4321 gaagacatac ttttcactga caggtacaaa tgataaagga aaagaaatcg ccgttatcat
     4381 tcctaaatct ggtgaaaaag taaaagtatt ggatcaaaca aagggactga ctgaaaacga
     4441 agcaaaacag acaattgctg cggcccatcc tgaaatccaa atcgaaaaag ctgctttagg
     4501 gatgtatgat gatcagcctg tgtgggaagt agtaggaaaa gaaacaaatg ggaaactgaa
     4561 ttattacctg attggctttg aatctggaga tgaagtcaag acaatcaagg gaatttaaaa
     4621 ggtaaaggaa tgaatgggat ggagttatca aaaagaacaa aacgattaga accgtctgtc
     4681 actttggcag ctgcggcaaa ggccaaggca ttaaaagcaa aaggcagaga tgtgctgagt
     4741 ttgactgtgg gagaaccgga ttttgcgaca ccagaaaaca tccaagaagc agcaatcgaa
     4801 gcaatccgca acgggaaagc tagctattat acaccaacag caggaatccc agagcttcga
     4861 caggcaatcg ttgattatct gaagaaaaac tatggacttg tctatgaacc ttcacaaaca
     4921 gtcgtaacag acggagcgaa atttgctttg tatacccttt tccaaacgat ccttgacccg
     4981 caagatgaag tcatcattcc tgtgccttac tgggtcagtt acggtgagca agtaaaactg
     5041 gcagaaggac ttcctgtctt tgtgaaaggg gaagaatcca atagctggaa agttactgtt
     5101 gaacagctag aacaagcacg ttcagaaaaa acaaaagccg taatcatcaa ttctccatcg
     5161 aatccgactg gaatgattta tagcaagaat gaactgcagg caatcggtga atgggcagta
     5221 aaaaatgata ttttgatagt tgctgatgat atttatggtc gtttagttta taatggcaat
     5281 gagtttactc caattgcaac gatttcagaa gcaatcaaaa atcagaacat catcatcaac
     5341 ggcgtgtcta aaacatatgc gatgacaggc tggcgcattg gttatgcggt gggaaatcct
     5401 gtgatcatca atggaatgat cgctgttgct tcccagtcaa ccagtaatcc gacagcagtc
     5461 agtcaatatg cagctgttga agcattgaaa ggcgagcaag atacagtgga agaaatgcgg
     5521 aacgcctttg aagaacgcct gaatacgtta tattcgcttg tggcagaact gccgggtgtt
     5581 tctcttgaaa agccacaagg agctttttat ctttttccta atgtaaaaga aacgctacgc
     5641 atgtgtaaat atgaaaatgt cacacaatgg gtagaagatc ttttagaaga aacaggggta
     5701 gcgcttgtga ctggcgaagg ctttggggca ccagaaaatg tccgcatgag ttatgctact
     5761 gatcgcgcta cgttagaaga agcggtacgc agaatcaagc aatttattga gagtaaaagt
     5821 caaaattaat cctaaagaaa ttcaaggaat ataaaaggag agtcatacgt ggaacaaatt
     5881 caaatcatcg attcgaaaaa ccatgtggga gaaacagtaa caatcggcgc ttgggtcgca
     5941 aataagcgat caagcggaaa aatcgcattt ttacaattaa gagacggaac agcctttttc
     6001 caaggtgtag ttgtaaaaag cgaagtgtcg gaagaagttt tccaaacagc taaaaatcta
     6061 caccaagaaa catccgtgtt agtaactgga gaaatccgtg aagacagtcg ttcaaaattt
     6121 ggttatgaaa tcggaattac aaatgtggaa gtggtaagcg agagccacga ttatccgatc
     6181 acaccaaaag aacacggaac agacttcttg atggatcatc gtcatttatg gctgcgttct
     6241 tcaagacaac atgcgattat gcagatcaga aatgaaatca ttcgtgcaac gtatgaattc
     6301 tttaatcaac atcattttgt caaaattgat ccgccgatct tgactggttc tgcaccagaa
     6361 ggcactacgg atctattcga aacaaattac tttgatcaaa aagcttattt atctcaaagt
     6421 ggccaattat acatggaagc tgctgctatg gctttcggaa aagtcttttc attcggtccg
     6481 actttccgtg ctgaaaaatc aaaaacacga cgtcatttga tcgaattctg gatgatcgaa
     6541 ccagaaatgg ctttcactca tcaagaagaa agtttagaag tacaggaaca atatgtagca
     6601 ttcttagtac aaaatgtttt agatcattgc gaatatgcat tagatgtact aggacgagac
     6661 aaagaagtct taaaaactta tacaaaattg ccattccctc gtattactta tgatgatgcg
     6721 atcgaattac tgaagaaaaa tggatttgat gacatcgaat ggggcgaaga ctttggttca
     6781 cctcatgaaa cgttcattgc gaattcattc gaacagcctg tctttatcct aaactatcca
     6841 aaagccatca agccattcta catgaaacca catccaacaa gagaagacgt ggtgatctgt
     6901 gcagatatga tcgcaccaga aggttacggt gaaattattg gcggaagcga acgggcaaca
     6961 gactatgatt tcttgctaga acaaatccgt aatcacggtt tggatgaaaa agaatattca
     7021 tggtatcttg atctacgtaa atacggttct gttccgcact ctggttttgg tctaggtctt
     7081 gaacgaacag tcacttggat tgctggtatc gaccatgtac gtgaagctat tccattccca
     7141 cgtttgttga accgaattta tccataagag gtgatgaaaa agctgttctg catcaagtaa
     7201 ttagaacagc caagcaaaaa cagctgttca tgtttttgaa ttggcgggac ttattaccgc
     7261 agatgtaagc ttttgaatac cgtttagtgg agaggttgtg aaaaagctgt ttagtttcga
     7321 gtattaagaa aaattttgtg gaaatggctt tccacatttt tgcataaatt tggcttaata
     7381 ccgagaaact ggcttttgaa caccgtttaa ggaagaggtt gtgcgcctgc cgttcagctc
     7441 cgagtcacaa ggagtaattt caaaaaacag tttttcatgt ttgatgacta ttgtgacttg
     7501 tgaccgagga gttggccgga gagcaccgtt tattctaaaa aagaactgcg aactctcgca
     7561 gttctttttt taaaatacgg gataaaggaa gtttccagca gacaagagaa gaaagcaaaa
     7621 gaaattgcta tttgattcac aaggttctat aacgaaatcg caatcaatca aacatttaca
     7681 aagaaggtaa ttcaaatgga aatctgattt gatgatgctt ctgctgttga aataaagcag
     7741 catctagcac ctgaaaacaa actaatagta acattcgaag atggagtagg tccgtatttt
     7801 cagcatgcaa taatccatat gtaagttcaa ttcacccttg aaatcatcgg accagataaa
     7861 gttatgacca atctatccca agcaatctag aagagatatt agtaaaggga catttactag
     7921 aagtcttaga tgagcctata aatatatgtt ctgatggcgt catcagtggt ctgattgacg
     7981 gaagcttagg tgtgatcgat ctctctggac caaacaacga aggaatcaag gggaatccgg
     8041 cacgttaaga aaaaaatagc ataaaaaact agacacttga tgagcgttca ttcaattgtt
     8101 tgaagggact aggctggtgt cattttttat acatatattt tctctttcgt cttgataggg
     8161 cttatgggat aatataagga agaaaatcat cgttttattc aaaaaggagt ttttgacaaa
     8221 tgaaaaaacg tatattattt atcggtgata gcattacaga cgcaggaaga gaccgagcag
     8281 aagcaactga tctaggtaaa ggttatccac ttttgattgc cggaaaacta atctcccaat
     8341 atccaacgat ggaatttgaa tgcatgaacc gtgggatagg aggagacaaa attgcagatc
     8401 tgcaagtacg ctggcaagaa gattgtttag ctttacaacc tgactatgta tcgattttga
     8461 tcggaatcaa tgatacctgg cataatacta gcgatcaggc tatattcgga actgagaaat
     8521 ctgctcagca atttgaatcc gtttatcgaa aattactaaa tgaacttcaa acagtgggaa
     8581 tctgcaacat catcttgatg gagccgtttg tacttcctat aaccgacgac cgtcatggct
     8641 ggcgtaaaga cttagaccct aaaatccaaa ttgttcgtaa acttgctaag gaatatggcg
     8701 cattgctggt tcctttagat ggtatattca atgctttagg gattgtttat ggtttttcga
     8761 aatatacaag agaagatggg gtccacccaa cgattggcgg acatgagatc attgcacaaa
     8821 gctggataga tgcaattgcc gcagtcgatt tttttagtgg agataaaaat gagcgaaaga
     8881 aaagtgagaa atgatggaaa tacggtgggc agtaaaagaa gatctacctc aaatcaatca
     8941 gctgattact gatcatccag aatcattcgt aaaagcaaaa acggcagctg acctaaatga
     9001 taagaataaa ctattgctcg ttgctgtaac aaaagaaaaa cggattatcg gatttgcgca
     9061 agcggacgtg caacagtcag aagaacgatt ggatcagcga ccatcaggaa aactaatcca
     9121 acacacatta gtaacaaaag aaaatacgga agaaatccaa aaaaaatttg cagaatattt
     9181 gatactggaa gctaaaaaaa gaagaataaa atcatttttt gcccagtttt aatcaaaaac
     9241 agtaatagaa ggagaaatac aatgagttgt ttaggaaatg tcatctggtt tatattcggc
     9301 ggactaatcg gtggtcttag ctggttagca gcggggatac tttggtgtat cacgatcata
     9361 ggtatcccaa tcggtatgca atgttttaag atcgcctccc tttcttttgc gccttttggc
     9421 aaagaagtaa tttatcacca gtctggcatg tcattgattg ttaatatcat ctggctgatc
     9481 gtttcaggcc taccaattgc tctcgcacat gtcgtcagcg gcatccttct atgtatcacg
     9541 atcataggga taccttttgc caagcaatct ttcaaacttg ctcgattggc gttgatgcca
     9601 ttcggtgcag aaattgtata aaagagaata ataaaggtta gataaagcat agagtcaggt
     9661 gggatacatg tatttcacct gactctatgc gttctcctgt ataagttctt ccatgtgact
     9721 tttacgtctt ttatttatat ggggttactg tttatggaaa gttgaaataa ttttcattaa
     9781 agaactcttt ctatattttt gaaagcgtag tggagcttcg aatatctggg aaggacattt
     9841 tgcagggatt gaaaaaagat attgtcctat cgaaaaatta atgaatttag acaaattgcc
     9901 agcaacaggc ttcaaactta gttgctatcc tgtcaagatc aagaaggcaa gtgcgggttg
     9961 gataagagca gtggcaatga tcgaaaagaa aaagaaagaa taagccaaaa catctgtatg
    10021 gaagaaattt tccgatgcag atgtttttca ttttttcttt cggatacctt gacatatgaa
    10081 taaccgttca tttataatta gttatgaaga gatattcata tgttgaggcg aggaggtcat
    10141 taaaatgaaa agttacagat tagaaggttt agattgtgcg aactgtgcaa tgaaaatcga
    10201 aaaaggagtt cagaagatca atggagtcaa ggaagcaacg gtaaacttca cttctggaaa
    10261 actaacgatt gacgcagagg aagatcattt ggctacgatt gaacaagaaa taaaaaaagt
    10321 agtgaaggaa ttagaaccag atgtcaaagt aacagaaata gataaggaaa aagtatctga
    10381 acatggaaat gaaaaagaga gaaatacgct gttccggatt ttattttccc ttgcaggtat
    10441 cgctttattg ctattatttg attttaatga accaattcgc ttgatagggt atttattgat
    10501 ttatctgctg ataggatatg atgtagtgaa gaaggcagtg atgaatatcg tcaaaggaaa
    10561 aatctttgat gagaattttc ttatgtctgt tgctacgatt ggcgctatgt tgatcggtga
    10621 atatccagaa gccgtagcag tgatgctatt ttatcaaatc ggcgagtatt tccaaggatt
    10681 ggcagtcagt cattcaagaa aatcgattcg cgaattgatg gcgatccgtc cagaaacagc
    10741 tcacgtgcag acgacggaag gattgatgac cgtgaaccct gaagacgtgc agatcggtca
    10801 gtttgtactt gtgaagcctg gtgaacgtgt accgttagat ggaacgatca tcgaaggaga
    10861 atcattagtc gatacgtcag cacttacagg agaatcagtc cctaaatctg tatatgttgg
    10921 tgaaacagta ttaagtggat ttatcaataa aaataaacca tttttagttc aagtagaaaa
    10981 atcttatgaa aattctacta tcagcaaatt attagaatta gtagaaaatg ccagcagtaa
    11041 aaaagcacca gctgaaaatt tcattactaa attcgcgcgc tattacacac cagtcgttgt
    11101 aggattggcc gttttattag ctgttttacc tccacttgtt gtttctggag cggcgttttc
    11161 tgaatggatc tatcgagcat tgacattttt agtgatctca tgtccatgtg cattagtgat
    11221 ctccgtaccc cttagtttct ttggcggtat cggaggagca agtaaaatcg gtgtattagt
    11281 aaaaggttca aattacttgg agttgcttgc acaaactgag acagtggtat tcgataaaac
    11341 cggcacatta acgaaaggtg acttttcgat ccagacgatc gatacaaaaa tcgatccaaa
    11401 gatattcatg caatatgttg cgagtgcaga acagttttct acacatccga ttgctcaatc
    11461 tgttttagaa ggctacgcag gtccgctttt accaacagct aatatccaag aatttgcagg
    11521 tgaagggatc ttagctgaag ttgatggcaa acaagtatta gcaggtaatc acaaattgat
    11581 ggaaagattt gaaatctctt ttccttcaag tcaagaaatc ggtacattgc tttatctagc
    11641 gatcgatcaa agttacagtg gttatcttgt tattgcagat accttgaaag aagatgccgt
    11701 agacgcattg gttcaattaa aaaaggctgg tgtgaagaac acagtcatgt tgacgggcga
    11761 ttcgaaaaaa attgctgatc atatcgggaa gcaagtaggc gtggacaaga tatatagcga
    11821 attgcttcca gaagataaag tgcagcggtt agaggaaatc ttacaaagaa acaataaaaa
    11881 gaccgcattt gtcggagatg gaatcaacga tgcaccggtg ctagcaagag cagatgtagg
    11941 aatcgcaatg ggtggattgg gaagcgatgc tgcaattgaa gcagcagatg tagtcatcat
    12001 gaatgatcaa ccatcgaaga ttgcagaagc aatccattta gcaaagaaaa cattgaaaat
    12061 cgtcaaacag aacattgtct ttgctattgg gataaaaatt ttggtacttg ccttaggtgc
    12121 ttttggtttt gcatcaatgg gagatgcagt atttgcagat gttggggtga cagtattagc
    12181 tgttttgaat gccatgcgaa gcttgcatgt aaaaaataaa cgttgatcaa tgaagaggac
    12241 gaatgaacgt cctctttttt ttatatcctt ttcttaatga aaaatgtaaa gaaaatagat
    12301 aggattataa aataactaat gtttttaatt ttgcagaaaa ttcaaaatag cttgaaattc
    12361 aataaggtaa atgaaataaa agaaaataac ttattttttt gatggaaaaa atatgaaaaa
    12421 acgatgtgta ttaaataaaa gaatacacac ataaaataac actgtcttgt aagtttgtta
    12481 aaaattgaat atgattacat ctggataaca aatttttatc ataaaggaga gaacgaatga
    12541 acaacaaaca attacgctgg tttactgttg cgttaattgc atttaacatg gtttggggca
    12601 tggggaatgt agttaataac tatgctcagc aaggagtatc agttgtcacc tcttggctat
    12661 tgattttggc catttatttt attccatacg cattgatcgt tggacaatta gggtcagcct
    12721 tcaaggatag taaaggaggc gtcagttcat gggtcgaaaa tacgacatct aataaacgac
    12781 tggcatacta tgccgcttgg acttactggg tcgtccatat tccttatttg gcacaaaagc
    12841 ctcaagcaat cctgattgct ggcggttggg cagtccaagg aaatggaaat atcgtaaata
    12901 cgatgtcagt acaaatggta gcagttattt cacttattat atttcttgcc tttttatatt
    12961 tatcaacaaa aggactttct actttgaaag tgattggcgg actggccgga acagcgatgt
    13021 tcgtcatgtc gatcttattt attcttttag ctgtaacggc accgttcatc aatccaacga
    13081 tggaatttgc cacaccacat atgaatcaag tgaaaacata tattccaaca tttgatttca
    13141 gttatttcac aaccgtttcg atgctagtat ttgcagttgg aggagcggaa aaaatatccc
    13201 cttatgtcaa ctctacaaga aatcctgcaa aggaatttcc taaagggatg atcttcttag
    13261 cagcaatggt agggatttgt gctgtattag gctcagtcgc aatgggtatg ctgtttgcta
    13321 gcgataatat tcctaaagac ttgatggcaa atggggcata cagtgctttt caaattttag
    13381 gtaattacta tggtatcggt aactcattga tgatcattta cgcattgaca aacatgattg
    13441 gacaaatctc cgcattagcc ttttcaattg atgcaccact aaaaatcttg ttagcagatg
    13501 cggatccaga atttgtacca aactggctac gtaaacgtaa tcgtaaaggt acattggtga
    13561 atggttatct tctgacaggt atactagtag gaatcattat tttgttgccg atctttggta
    13621 tcaaagatat gaatgaatta gtaaaatggt tgacgaactt gaactcagtt gtcatgccaa
    13681 tgcgttacct atgggtgttc ttggcatata tgatgttgaa taaagcttat aagaaattca
    13741 attctgaata taaatttgtt aaaaatccaa aaatcggttt tatctttggt gcttggtgct
    13801 ttgccttcac tgcgtttgca tgtatcctag gaatggtgcc aaaagtagat tatactgctg
    13861 atcctaaagc atggtggttc caattattca cgaatatcat cacaccaatt gtcttgatct
    13921 tattaggtat gatcttgcca gcaattgctc gtcgagacaa aaacaaagaa atcactgaac
    13981 cagaaacagt ggttcagcct taaaatagaa atacttgtta caagaggttg tgacagaagt
    14041 ggtcagcttc aagaaataag aaggaattta cgaaaattgc ttctcaaatt tttgtgaagt
    14101 ttcggcttgt ttttcgcaga agctacttct ggaacaccgt gaatcagagg ttgtgaaaaa
    14161 gctgtcctgc atcaagtaat aagaacagcc aaacaaaaat agcccctcat atttttcgtt
    14221 ttgctgggct tattaccgca gatgcaagct tttgaacacc gtttaagaaa gaggtagtga
    14281 gcctgccgtt taactccgag tcacaaggag caatttcaaa aaacaacttc tcatgtttgt
    14341 tgactattgt gccttgtgac cgaggtgttg gcaggagaac accgtttaag gaagaggttg
    14401 taaaatcagc gatttgacct gagtattaga ggaacaaacg aaaaaatagc tcctcatatt
    14461 ttgccgtttt ttgagttaat gctgaaggtc agctgattga acaccattta ttcgaaacaa
    14521 gggactttga cacgactttt gtcacagtcc cttg
//
LOCUS       DARPZF010000062        13778 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.065, whole genome shotgun sequence.
ACCESSION   DARPZF010000062 DARPZF010000000
VERSION     DARPZF010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13778
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.065"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(45..1364)
                     /locus_tag="SLE65_002351"
     CDS             complement(45..1364)
                     /locus_tag="SLE65_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEI8449614.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="SLE65_002352"
     CDS             complement(1361..2014)
                     /locus_tag="SLE65_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8449615.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2302..2822
                     /locus_tag="SLE65_002353"
                     /pseudo
     CDS             2302..2822
                     /locus_tag="SLE65_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2724..3440)
                     /locus_tag="SLE65_002354"
     CDS             complement(2724..3440)
                     /locus_tag="SLE65_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HEI8449616.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(3564..3749)
                     /locus_tag="SLE65_002355"
     CDS             complement(3564..3749)
                     /locus_tag="SLE65_002355"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449617.1"
                     /translation="MTKALIFDFDGTMIDSEWMFYESIHHYLLKPIYWSSSAIKFLLQ
                     TINKVLGRQQNCPFMKG"
     gene            3976..5249
                     /locus_tag="SLE65_002356"
                     /pseudo
     CDS             3976..5249
                     /locus_tag="SLE65_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5356..6387)
                     /locus_tag="SLE65_002357"
     CDS             complement(5356..6387)
                     /locus_tag="SLE65_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8449618.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(6394..7224)
                     /locus_tag="SLE65_002358"
     CDS             complement(6394..7224)
                     /locus_tag="SLE65_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8449619.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(7221..8036)
                     /locus_tag="SLE65_002359"
     CDS             complement(7221..8036)
                     /locus_tag="SLE65_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEI8449620.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(8033..8857)
                     /locus_tag="SLE65_002360"
     CDS             complement(8033..8857)
                     /locus_tag="SLE65_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HEI8449621.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(8847..9947)
                     /locus_tag="SLE65_002361"
     CDS             complement(8847..9947)
                     /locus_tag="SLE65_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEI8449622.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCVSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            10125..10910
                     /locus_tag="SLE65_002362"
     CDS             10125..10910
                     /locus_tag="SLE65_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HEI8449623.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            10943..11326
                     /locus_tag="SLE65_002363"
     CDS             10943..11326
                     /locus_tag="SLE65_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HEI8449624.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            11402..11533
                     /locus_tag="SLE65_002364"
     CDS             11402..11533
                     /locus_tag="SLE65_002364"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEI8449625.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            11502..11738
                     /locus_tag="SLE65_002365"
     CDS             11502..11738
                     /locus_tag="SLE65_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEI8449626.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(11816..12787)
                     /locus_tag="SLE65_002366"
     CDS             complement(11816..12787)
                     /locus_tag="SLE65_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HEI8449627.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
     gene            13439..>13778
                     /locus_tag="SLE65_002367"
     CDS             13439..>13778
                     /locus_tag="SLE65_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8449628.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVSQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYSFEEKIP
                     HFSTFGKNYVR"
BASE COUNT         4179 a         2995 c         2387 g         4217 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgacg ccttctgttg
     2101 ccaatacttt ttcttttttt taataaatgc aaacagacac cttgaaatcc tttagaaaaa
     2161 aggcttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac caaaacatca
     2281 ccctaccaaa ggagtcgctc tatggataat catactagaa aattactcgg attaacagat
     2341 aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg cgttcaagcg
     2401 cagtttatta aagggagatt ggatgactca ccttcccatt gtgaacactg tggatcgatt
     2461 cgtattatcc gcaacggttc ctatacgaca cgtactcaga tgttgaaagt caaagaaaag
     2521 ttgactattt tagaattaaa acgtacccgt tttctatgct atgattgtgg gcagaccttt
     2581 tctgcgaaaa cggacttagt tgatgaacat catcaactaa caaaggaact gaagcaggcg
     2641 attctcatag aactgtacga aaatcaatca cgtaatctga aaatcagaag aagtaccgtc
     2701 ggctcaagcg atattggaaa ctcttactca aagattccac gacattggag ccgctcaaac
     2761 ggcattatca tcgactgttt aaacgaccaa ttagtcaaac agaaatcgtc gatgaaccgt
     2821 tgtgcacaat ggtgtcctga acgtacagcg acaccttcca tatccagagc agtcgccaca
     2881 tcacggggat ggatgccatc caaattaaaa gcaaccacgc cagtatgatg ttcaggatct
     2941 tgcggtccgt aaatggtgat accgccgatc gcttgtaatt taggtaaaac gtaggcaacc
     3001 agttcttgct cataacgatg aatattctcc ataccaatct cattcaagta atcgattgct
     3061 cctgcaatgt tcggagtacc agcttcaaat ttccatggca gctctttcca tgaactatcg
     3121 taaagattga caaaatctat catttcaccg ccgaattcga ctggctccat ttgttctaac
     3181 aattgacgtt tgccatataa tacaccgatt cctgtcggcc cgcacatttt atgcccgcta
     3241 aaggcgaaaa aatctgcatc caacgcttgt acatcaactg tcatatgcgg tgctgcttgg
     3301 gcaccgactg gactatcctc aactacaaca gcctgttcaa ccctcagccg tttcaagcac
     3361 aacaaataac cttctggatc tggtttgccg acctgaagat catcgatcgt cacaaaggaa
     3421 tcaatttttt ccttaatcat cggatgtgct tcaaaaaaat agtctagctc ccgcagttca
     3481 gaattgagac tactccgatt ttccagtgct gctgatccgc tgctcaaaat gttcagcatc
     3541 cactggtctc ccaaccgctt gacttatccc ttcataaaag gacagttctg ctgccgtccc
     3601 aacaccttgt tgatagtctg caaaaggaat tttatagccg aactgctcca gtaaataggc
     3661 ttcagtaaat agtgatgaat actctcgtaa aacatccatt cactgtcaat catcgtccca
     3721 tcaaaatcaa aaataagtgc tttggtcatc ttctttcccc cttacccaaa acaagcaaaa
     3781 gctgtgtcct gctctctcta cagtatcagc ataaaaactg ccgtctgaaa agtcaaaggt
     3841 gaaagaaatg tggcgctata atttctagga ctgatagtaa atcattctat cagtcctttt
     3901 gagcataaaa aaacaaaaca tacagaagct ccgttagaat tgaatcacca caacacaatc
     3961 aaaggagcgt tctgtatgcc tgatcttcat cttatcaaac tattactagg aatcaaagat
     4021 ggaaacattc aaatcactca tgtcgagaag aaaaaaatac attcaatcaa cagtatcgtt
     4081 gtttctgcca cgctcattaa aacgattcag ccctgtcctc agtgtaaaca ggtgaatcaa
     4141 catgggctga tcgttaagaa cggaaagaaa aaatcgctgg tccttctcaa taagtgtgcg
     4201 aatcaacgga cttatcttgc tttggcaaag caacggtacc tctgtcgtgg ctgtcacacc
     4261 tattttacgg cgaataccta cattgttgaa aaaaactgtt ttatcgccaa acaagtacat
     4321 tataaaatat tggaggaatt gactgaaaaa caagcaatga cgacgatttc taaacattgc
     4381 ggcgtttctt ggtcaaccgt ttcgcgaaca ctcgcttctc tgctccccat gacaaacgtg
     4441 aaaataaatt ggttgcctcg ctgttcattg gtagatgaat ttcgttcatt gaaaaatcaa
     4501 gtcggtccct attctttttc ttgtatggat ggcgatactg ggaaattact ggatattctt
     4561 ccttcacgta agaagaaaga tctcatttct tattttatgc aatttgaacg acgtgcacgt
     4621 ttaaacgtaa aaatactcgt aacagatatg aacgcctctt atgctttgct gataaaagag
     4681 tgctttcctc atgccaaact cgttgtggat cgctttcaca tcgtcaagca cctcattcgc
     4741 agttttaagg atatttgact atgagtcatg aaaagcttcg accgaaacga tccaatacaa
     4801 gccaaacact atcgacaagt gaaggcttta tctcgacttc tgatcaaacg acaggacacg
     4861 cttgtttatg ataaatggac aaaatggcgt aattttggtt gggcctattt aaccgaaagt
     4921 gaagtcgtag aacgtctact ttctacttct gatgaactac gaatagctta tgcttactat
     4981 caagaaattc ttcaagcttt ttatgacaaa gaagcggaca tcttctttca gcttgtaaaa
     5041 acaatgccca agtcggttcc aagagaactg catcatataa aaaaagcgtt tataaactat
     5101 gaatccggca ttcgtttagc cttagagttg ccttactcaa atgtcaaaat agaaaatctg
     5161 catacccaca tcaaagcatt gaaacgaata gcttacgggt taggatgaga accagaattt
     5221 tcttaatcaa tcatctgatc acttattaaa cataaaaaaa catctaaagc agaaaatcaa
     5281 ttctacctta gatgttctta tatcactcta tcagtcctat ttgacaaaga gccagaaatg
     5341 tttgccgact atacactagc tttgttgtgc aaaatgctga gtatcaattt ccacagggat
     5401 tgctagaata tctttcagct gaatgtataa ggcatcgcta attttctctt cccgatcgtt
     5461 caaccgatcc actaaaattt ctttgccctc cagcgtttga aaaacatacc gttgaatgtt
     5521 gcctaaaata aatgattcct tccatagaac cggaatctta accccctgag gaaccggttc
     5581 aaattgaatc agctccggtc ttaaataata aatgcagcga ttgcccttag cggaaaactc
     5641 gtgggtatac tgattcagct cataccattc gaaacgatta tagttgccga taaattccgc
     5701 aacaaatcgg ctctgaggat tctgatacaa ttccttcgag gtggaaacct gagccacccg
     5761 cccagcttcc atcacaaaaa tccgatcact gattcgcatc gcctcttctt ggtcatgagt
     5821 cacaaaaatc atcgtcatcc ctagcgattg ctggatagcg cgcaaatccc gctgcagctg
     5881 ttttctaatt cgggcatcca aagcacttaa tggctcatcc agcagcagga ctttcggttc
     5941 agtgaccaat gagcgagcca gtgccacccg ttgtcgttga ccgccagaaa gaaactggac
     6001 atttttatct gcctgctccg tcatatccac caatgatagc atctcaaaaa ccttttcctg
     6061 aatcacctca ggactcagct tctttacctt caaaccaaag gctacatttt caaaaacagt
     6121 catagttgga aacaatgcat actgttgaaa aacaaagccg atattgcgat ccttcgtagg
     6181 cttatcggca atattctcat tgtccagcac aatctcaccg ctctttggtt gttccaatcc
     6241 cgtgatacag cgcagcaacg tagactttcc gcacccgctg ggacctagta aagtaaccag
     6301 ctcacccttt tcaatctgaa tttcatcaat agctaaaatc tgtttttcat caaaaaacag
     6361 attgagatca tgtatttcta aaaacatttt ccgtcacaac tcctttaagg gcttcttttt
     6421 cgactgcttc tcttccctcg tctgcttaag ggacagctgt tgcttttgtc gataagtcag
     6481 cataaaggta gttaaagcaa ttcccaccat aaacagcaaa tacaaaacca tcacagcgct
     6541 agccaaatgg ccgttttcgt tcatccgccg cagcatatag atgcgtaccg tctgaaatcg
     6601 accgccaatc aacaggttcg tcagcatgta ctccccaaaa accgaagaaa aaatcatcag
     6661 agaaactagg gtcacaccga tacggatgtt tggaaacagc acctggataa taatcgtaga
     6721 catcggggcg cccaaggttt ctgctgcatc cactaattcc ttcagattaa ttaagcgcat
     6781 ctggttgtta agactaagat agacaatcgg caacgccgta ataaacaatg cacctaccaa
     6841 cactacaaac attgggatac cagtttcagc atacgttcga agcaaagccg ttaccaaaat
     6901 cactcctggt aaagcatacg gcagcaggag cagcttttcc agccaacgat tcaaacgagg
     6961 gaaatacaaa tgaatccaaa taatggtggg aatcatcaac aacagaatcg tcaccaagac
     7021 cacacctgct aataaaagtg agcgacccac cgcagcaata aattccctgt ccgtcagcag
     7081 ctgttggaac cattgcaagg taaaatcact aggtaaaagc gattttgacc atttagtgga
     7141 gctggcatac aaaatcgttc caataatcgg cagcaagtaa tacaggacaa agcagaacaa
     7201 aatcggtttt attaactttt tcacgtctgc accaccttgc ctttcttttg aataatcaac
     7261 attgccgtta ccagcaggac acctaaagcg actgccaacg cactgcctaa attaggcttg
     7321 gcgaacacat ctcccgacac taaagccgca attcgaatcg ttaaaagatt tacattactg
     7381 ctggtcaggg catacgctgt ttcataggtc cccatgccat tagcaaataa gatgacaaag
     7441 gtgctggcaa tcgatggtcg caaaaaaggc aaagccacct tgaaccaagc atacgctgat
     7501 gaagcgccca gcaattgtgc ggactccagc cattcctttt tcacttcctt catgctggga
     7561 tacaaaaaca agacccctaa cggaatttgg aaataggtat acgtgatggt caatccccac
     7621 caagaataca aattgaagtc cgctagaaat ggcaaaatca ttttcagcac acctacattc
     7681 cccaacaaaa taataaaaga gaatgccagc ggaatcccag caaaattagc tgccaaattg
     7741 gaaacaaagg tgattttctc ctgcaattta gtcgatagat tcattaagca taaacataaa
     7801 ataaacgtcc cgattaaccc aatcacactg gagctgacag caatcagtac gctgttaaca
     7861 aaggcctgtg tgtaatattt gttgctgaaa atatcactgt aattggccaa tgtccactgg
     7921 ttagttaaat cactgtgcaa gctgcacaga accataaaaa gcagcggcag cagtaaaaat
     7981 gcacagaaga taaaggaggc aggaaccaga accaagcgtt ttttcatctc tttcatcccc
     8041 tcatcaattc ttgaatgtcc tgcattttct ctgacggtgc aattcctaat aaccagcaaa
     8101 acaatggagc cgccagcagc tgtggtacag tttgttcctt cagcttttgg cgtttatttg
     8161 aaatcaaata aaaaggaact tcacgatgtg cagccaagct gccgccatgc agtccgtgcg
     8221 catccatccc gtgatccgca gtcaccacga cttgataacc tttttgcagc cattcaggaa
     8281 ggtaaatagc caataatctg tccgcctgat taaccgctgc tgcatattca tgagaatcgg
     8341 cggtaaattt gtgaccgaca tcatcaatat tcatcgaatg tacgaccaaa aagtctggct
     8401 gatactgatt cactaaataa tgggcatccg caaataaatg cgaatcaggg taagtgtcct
     8461 cactataaaa gatgccatgc tgaatcagtc gctcctcctg atgctggatg cgatcaacca
     8521 aacgattata gggggcttga ttgtacaact cgctgtacca gtggtaagcg gcggctcctg
     8581 tttttccgcc agcttcctta actaattcaa acagcgacca ctctttggat cgctgagcat
     8641 ggtaattact atagatgcca ttttcatagg ctggaacgcc ggtcatcagt acttcgtata
     8701 acggacgtga attgctgggc agctcacttt ttaccttcaa taagcttgct tgctggtgct
     8761 caactaaatg attcatgaac ccaagctggg cgacggctgt gtcgtagcga cagccgtcta
     8821 gtataactac aatcagtttg tcaagtctac tttgcatagg tcagtacctc cgcctgccaa
     8881 agctctggaa gctctacaga ggtcttgttc caagcttcat tgtcttcaac tggcaccgcc
     8941 gcttcataag catcctccgg cagtaatttt tcagctactt ctttaggcag ctctaccttg
     9001 cgaataggtc gcgcatagcc ctttgccaaa ttgatttgcc cttcatcaga taaaatatat
     9061 tcccgtgcta gctttgccgc attgggatga ggggcatttt tattgattaa ggttgtatac
     9121 ccgctaatga tggagccgtc tgttggcaca gttacctcaa aacgctcgga gtcaatttgg
     9181 tcacgataat ttagtccatt gaagtcccaa acaactgcca catcgatttc acctttttca
     9241 agatttgcta cgctggcatc aacggtggac aaacggcctt tttctgccat ttttttgtag
     9301 taattcagac ctggctgaat atccttttcg tcacctccgt tggcaatcgc cgcagccaat
     9361 acagcaaatt gtgcttggtt ggcaatcgtc acatccccca cgctaacttg atagtcaccc
     9421 tcttgcagct ccttccagct agtcggtgct tgcttcacat tctctttatc ggtgataaag
     9481 gaaatggttc ccgtatagct taacaaccaa tccccatcat catcctttgc ccaatccgga
     9541 atttcctccc aatagttggt cttataaggt aaggttaact ctttgctttc agccaacgga
     9601 ccgaagctga taccgacatc accaatatcg gcggttccat tttttccttc tgattcaaac
     9661 ttagccaatt cttctgcact ggacatatcc gtatccacgt gacttaagcc gtattctttt
     9721 tcaaggtcgt tccaagtgcc tacccaattt gcccaagtat ccggcattcc caagctggca
     9781 atctctcctt cttccttggc tttttctata atcgtatcta aagagtcgtc tgccgcagcc
     9841 gattgcttcg ttgcttcacc tgagacgcag cctgtcagca ggatacttac tgttgctgca
     9901 caaaataaac cgatagtcat gttacgaatt ttttcattca ttttcattca ttcttctccc
     9961 ctttcgataa ttccattcta acaaagcttt gtaatgagag aatcagtttc ttgaaaaggt
    10021 ttcatgaaca atgtaaaggt tgtatatggt ttgtaaattt cgacgaattc ccgttaacct
    10081 tctaaagctt ttgcggtatg atagtagaaa aaaggaggct ccctatgcag tattatgatc
    10141 agcatctcca cacgtatttt tcctttgatt cagaggaaaa atttgaaaac tatttagcct
    10201 atcagccgga gtttttcgtt tctacggatc actttgattt aaacaatcca tctaccggaa
    10261 aagatgacat tccggattat ccagcctata taaacaaact ggactcttta aaagaaacct
    10321 attccaccaa atttctgcga ggtatcgaga ttggcgttgt tccaggacaa gaagagcgga
    10381 tcgtggatta cctcgctcag catccttatg atttaaagct ggtaagtatt catcaaaatg
    10441 gccgctttga ttatatggac gatgtggttt taaccaaaga tcccattcaa actaccaagg
    10501 aatattttga tcagatgttg caggtcttga cggattttcc agaaggagat attttgactc
    10561 actttgatta tggattacgc cgcttcacct tcacagcgga agaattcgcg gagcattttg
    10621 aggctcagct gctaacgatt ttcaaaaagg ttgttgaacg agaattggcg atggagttaa
    10681 atgccaagag cttcttgaaa tacggcaacg aagaccttta ccgttatgcc gttcctttgt
    10741 atcaaagtgt cggcggaaag ctctttacct taggctcgga tgctcatgtt gccgaagatt
    10801 atcagctggg ctttaaaaaa atgagtcagc tgttggcaga ctgtcaggta gaaaagttgc
    10861 tagtcattca aggaaaagaa cgccgcctga cgccgctgcc gattttgtga ttcctatata
    10921 atagaagaaa gtggtgaaaa aaatgagcaa cctgtgggac tacaatcaag aggcacccat
    10981 ccattattta attgcgcgac attgggatgc gttgaaaatt gaggcggttt gccgatcctt
    11041 gttagcagcc gttccaaaac aacaactgga aaattttttg gtggctgaca gcttgcagcg
    11101 ggaaaaagtt caggcttatt ttgcagcctt taaagatcag cctttggaat atttgcatgc
    11161 gcagtttcat cttttttatc aagtagccgc cccagatgac tacaacgatt tacgaggaca
    11221 gctgcaattg acctttcaag cggatgaaac cgcctatacc gttttattgg gaatggctcg
    11281 ccttggtgat caggcgaagg tcgagtggcg gattttcgat atttgatggc aggatcaagg
    11341 cgtttcagtt gcaaaccttc ctctctttca attagaaaaa ccgcagcagg aagaagtttg
    11401 tgtgctggtc accgatgctg gtgaaattcg tctccgctta tttcctgacc aagctcccct
    11461 ggctgtagcc aactggcgct ccctagctga gcaaggcgtt tatgacaaca cacctttcgg
    11521 ctcgtgtcat taaggaattt gttattcaag gtggcgcttt ggatggttct ggtgatgaag
    11581 ctgtttccag ctatgagggc tttttcgctg atgaagtgca tcgcggactt tatcatttta
    11641 atggcgcctt ggccttaggg gaccacggcc cccacaccaa cggcaaccag ttttttattg
    11701 tgcaaaacac aaaggcgcag gctgacctgc taatgtaaag caagcatact tggagcttgg
    11761 aggactaccg gagctggatg gtcgttatac tgtttttgga caggtatacc aagggttaga
    11821 aatcgtagca gcgatcgcag ctcagccgac aaacagtgaa gatgtaccga ttgagccagt
    11881 gttcattcga caaattaact tcgaaaaaac atcgtaaaaa gacactcact gacttcagca
    11941 aaagctctat tcttgagctg gctgcagcta gtgagtgtct ttcatttatc cataagataa
    12001 agcttggatt caataaataa ataaatgttt tggttaaagc tgtgaccagc aaatgaggaa
    12061 ccgtgcgagc cagttgatct gccaatgcaa acatttcttt aggtgaaggc gctggcgtgt
    12121 ctgccaacgg atactccagt cccaatgctt ggtaaccgtg cataccatag cagtggtacg
    12181 gtagtaattc taacggtacg aaccgatcaa gatctgccac aaaacaagca atcgtcagca
    12241 gctcggtcag gttcatattg atacctggaa ccacaggaac tcgaattcgc acttcgcagt
    12301 taggatactc aattaaaaag cgacgaatat tcttcaaaat ttgttggtta tctaagccgg
    12361 tccattgttt gtggagcttg ctggtaaaca tttttacatc cacaaacaat gtatccacat
    12421 agggagctac cttttggatt tcattataag caccacaaaa gctggtttcc agtacggtat
    12481 tgattccaat gtatttcgat ttttgcaaaa tttctttagc aaaatccgcc tgaaccagtg
    12541 cctcgcctcc gctaatggtc actccgccat ccgagtgaaa gtaaaaaaca gcatccttct
    12601 caatctcatc cattacctct tcagcggtca tggtctggcc aaatcctttt tcaatctgct
    12661 tgctttgtga ttcgggaatc gaacaccagg cacagcgtaa tgggcagccc tttaaataaa
    12721 caacggtccg taaaccagca ccatcatgta gagaaccctg ttctattctt aatactgttc
    12781 cttccatata gatttttgaa ttacacacta gtttaaacta aaacacacaa ggaaaaactt
    12841 accatttaat cataaaatta gctcatataa atatactagg atgtaaaata gactggtcaa
    12901 aatctggtca aaaaagagga ctaatacagg tagtcctctt ttttgttatt ttaatattct
    12961 aaatcatttt ttattggttt attcccttat tcgatgtaga ctcaaatcac tatatcacta
    13021 gatatcaaac ggcgtcatac ggaatcaaaa acatcaaatt tgacctgtta aatggtcatt
    13081 gaataacatt caaaatcaat aaaacggagt cagacacgga gtcaaaaacg ctgagagtaa
    13141 aaaatatata cagccttgta ggtaaagtac cacagggctg tatatttttt atttcagatt
    13201 accttaaatg attccattta ctttttatct cattttttcc tactagttag tatcaaatac
    13261 tctcctattt tctcaataaa ctatttttgg atacatggta tctgaaacag ctaaaacctt
    13321 gtcattacag caaaaaatca cgttatccag actgtagaca aagtccattt tatggatgat
    13381 gtctacagtc ttttctttta taatagattt atgaaaacga atgcaaggag tgatagctat
    13441 gatgtctaaa aacaatacga atggtagaaa tcaatttgcg atgcttacga ttgatgatct
    13501 agtttctcaa gatcatctcg ttcgaaagat tgatgccgcg cttgattttg aatttattta
    13561 tccaatcgtc gaagccactt actccgattt aggtcgccca agtatcgatc cagtgattct
    13621 gatcaaattg gtgtttattc agtatttatt cggtatccgt tccatgcgac aaaccattaa
    13681 ggaagtcgat accaatgtcg cttaccgctg gtttttaggc tactccttcg aggagaaaat
    13741 cccccatttc tcaacttttg gaaagaatta tgttcgcc
//
LOCUS       DARPZF010000063        13488 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.066, whole genome shotgun sequence.
ACCESSION   DARPZF010000063 DARPZF010000000
VERSION     DARPZF010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13488
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.066"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(164..388)
                     /locus_tag="SLE65_002368"
     CDS             complement(164..388)
                     /locus_tag="SLE65_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HEI8449629.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(586..2166)
                     /locus_tag="SLE65_002369"
     CDS             complement(586..2166)
                     /locus_tag="SLE65_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEI8449630.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2567..3943)
                     /locus_tag="SLE65_002370"
     CDS             complement(2567..3943)
                     /locus_tag="SLE65_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEI8449631.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(4071..5189)
                     /locus_tag="SLE65_002371"
     CDS             complement(4071..5189)
                     /locus_tag="SLE65_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEI8449632.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            5331..5765
                     /locus_tag="SLE65_002372"
     CDS             5331..5765
                     /locus_tag="SLE65_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8449633.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5843..6376)
                     /locus_tag="SLE65_002373"
     CDS             complement(5843..6376)
                     /locus_tag="SLE65_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEI8449634.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="SLE65_002374"
     CDS             complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="SLE65_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEI8449635.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7641..8438)
                     /gene="recX"
                     /locus_tag="SLE65_002375"
     CDS             complement(7641..8438)
                     /gene="recX"
                     /locus_tag="SLE65_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEI8449636.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8545..9927
                     /gene="rlmD"
                     /locus_tag="SLE65_002376"
     CDS             8545..9927
                     /gene="rlmD"
                     /locus_tag="SLE65_002376"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEI8449637.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(10101..10679)
                     /locus_tag="SLE65_002377"
     CDS             complement(10101..10679)
                     /locus_tag="SLE65_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HEI8449638.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            11001..11471
                     /locus_tag="SLE65_002378"
     CDS             11001..11471
                     /locus_tag="SLE65_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HEI8449639.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(11579..12805)
                     /locus_tag="SLE65_002379"
     CDS             complement(11579..12805)
                     /locus_tag="SLE65_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEI8449640.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT         3960 a         2719 c         2248 g         4561 t
ORIGIN      
        1 taaagaacac ttttgtctca cgctctaaac acgtataaac ggcgaaagca gaagcaactc
       61 cttcggaaat aagctgaaat tcacgaaaat tgcttttcaa atttttgtga attccagctt
      121 atttcttgga gttaaacgct tctgtctcag cctctttttc tttctagctt tttgattttt
      181 ctcttttctt ttgtactttt ctcttttcat tttcagttct acgcgtgtct ttatttttaa
      241 ctttttcctc tttatggatg attgatcgta ctttttgtgc aatttgctcg tttttgtccc
      301 agtcttttac atctaataat cgacataatc gtaacatctc ttcttttttc tgtttttttc
      361 tttcacgtct ttgccattct gtttccatgt gtcacactct cctttcttta atcatatgta
      421 cgcaaaataa tttttatatt tttttgatta gacatttcta tgattttaat atagtaaaaa
      481 gagccgtcac ggaaaatccg tcacggctct aaacaaaata tgagaggctg tttttgtttg
      541 gctattctta ttacttgatg cagggcagct tgtgtcaaga cttctttaca tcaaactttt
      601 taattttaca ttgggatatt tatccgcaaa ccagcgttct gcaaattggt tctcgaataa
      661 gaacaacggt tggtcgaaac ggtcacgagc caagatattg cgacttgaac tcatcttctc
      721 atccaaatct tctggatcga tccagcgagc gattttgtgt cccattggag acatgattac
      781 ttcggcgtta tactcattta acatacgata ttggaatact tcgaattgta gctgaccaac
      841 agctccaatg atatattctt ccgttagata tgttttataa agctgaatcg ctccttcttg
      901 aactaattga tagattcctt tgtggaagga tttttgtttc atgacatttt ttgcagtcac
      961 tttcataaac agctctggag taaatgaagg gagttcttca taagcaactt ttagttttcc
     1021 ttcgaacaat gtatccccaa tctgataatt gcctgtatca tatacaccga tgatatcgcc
     1081 tgctactgct ttttcgacgt tttctctcga atctgccata aattgtgtga cattgcttaa
     1141 tttcagtttt ttatttgtac gttccaacca gacatccatt cctcgttcga atgttccaga
     1201 acagattcgg acaaaagcga ttcggtcacg atgggctgga ttcatatttg cttggatctt
     1261 gaatacgaaa cctgaaaatt cttcctcata aggacttacc atctgatcat cttgtgtttt
     1321 gtgtccataa ggagctggtg ccaattcaac gaaagtctct aaaaaagtct gtacaccgaa
     1381 gttagtcaat gcagaaccaa aaaatactgg tgtctgatcg ccacgagcaa ttttttcttg
     1441 attaaatgca tctccagcct ctttgattag ttctacttct tctaagactt gttcatataa
     1501 ggaattttca gttagaggat gattttcggg aagcagtcca tcttcatcca attctactaa
     1561 tcgttcatcc tgataatttt ccggacgata aaactctaca cgattatggt agatatcata
     1621 aagaccttct agccctttac ccataccgat tggccaattc atcggataag attcgatatc
     1681 taatagctct tctaattctt ctaacaattc caatggttca cgaccatcac gatctagttt
     1741 gttgataaaa gtaaatatcg ggatgccacg tttttttaca acttggaata atttctttgt
     1801 ctgtgcttcg atcccttttg cactatcgat taccatgacc gcactatcca cggccatcaa
     1861 agtacgataa gtatcttcag aaaaatcttc atgtcctggt gtatccaaga tatttactcg
     1921 tttcccttga taatcaaact gcataacaga actagtaaca gaaatcccac gttgtttctc
     1981 gatttccatc cagtctgatt tggcaaaatt acctgttttt ttgcctttta cggtcccggc
     2041 ttgacggata gccccaccaa acaatagtaa ttgttctgta atcgttgttt tcccagcatc
     2101 cggatgggaa atgatcgcaa aagttctgcg attgtccact tgttgcttta attttggatt
     2161 attcataacc taactccatt tcttccattc aattatttat attttctcta ggcacagatt
     2221 gtccgatctc ttaaagaaag acaatttcat atagggctgt gacaaaagcc gtgtagcagt
     2281 ctctttttcc gagtaaacgg cgttctagag acagcctatc agcaataagc ccacccaagc
     2341 caaaaatacg aaaagctgtt tttgcttggc tgctcttatt acttaatgca ggatagcttt
     2401 ttcacaacct ttgtcaacta ctacaactga atcagtatag catggattca gcgaatgaaa
     2461 aagccaccaa accataagag tcaaatattt ttttgtcagc tgactaaaag aaaagacgtg
     2521 ttgcttgttt attcaagcaa cacgtctttc ataaccaagt ttccaattat cttcttggct
     2581 cgtcatcttc gaattctttt ctgaagtatc ttcgttcttc ttcaggttcc gcttctgttt
     2641 cttccggatc atgaaaaatg acacggattt taaggattcg agaaccttcc atttcttcag
     2701 aaaccagcgt aatattatcg acatcaaacg ataacttttc gccttcatcc ggaatcatgc
     2761 ctaatgctgt aatcaaataa ccagccatcg tatctacatc actcatatgc agatcactgt
     2821 caaaagcttc attgaactca tcaatcagca tacgtccttg gatgatatat tcgtgttcat
     2881 cgattttttc ataaagattc tcaacttcat ctgattcatc atcgatttct ccgacgattt
     2941 cttctaaaag gtcttctagt gttgctaacc caacgacgcc gccatattca tctaataaaa
     3001 tagccatctg attctgcgtc tttttcattt catataacag atcatcaata aagaccgttt
     3061 caggaacgaa taaaggctcc tgcatgattt tcttgatatc taaattatca aagccgaatt
     3121 tatgggcagc ttttagtaaa ttctttgtat gaaggattcc gactacttta tctttgtctt
     3181 cgttataaac agggattctt gaatagtttt cggataaaac ttcattcaca ttttcttcca
     3241 cagtgtcgtt gatatcaatc ataaatgcat ccgttcgtgg gaccatgact tctcgggcaa
     3301 ctttcgtatc aagagaaaaa accccttgga gcatttctaa ttcttcatta ttcaatacgc
     3361 cttcgttttc aagcatataa cgcatttcat ctctggtcat ttttgaatct tcatcatcaa
     3421 aagtcatcgg cgtgatacgc gccaataaac ttgtggaagc agaaagcagc cagacgaagg
     3481 gcttagctac tacaccaatc aagcgtatca gccctgaagt gaactttgcg acttcttctg
     3541 atttatttaa agcaatacgt ttagggtaca attctccaaa aacaatcgat acataggtca
     3601 aaatagccag cacaatgata tttgcaatat tttttgccgc tgtgccgcca cctaataccg
     3661 gagctaaccg ttccgataaa gtattagcta gtgaagcacc agacaaaatg ttgaccaaag
     3721 tgattcctac ttggattgtc gataggaaat tatttggatt ctgcaatatt tttaaaagct
     3781 tttgagattt cacatctcct tcatcagctt tttgctcgat tcgattctta ttgatcgaaa
     3841 caacagcaat ttcggaagct gctaaaaaag cattgatcaa tgtcaaaacg atcaataata
     3901 aaatctgcgc taacagcgac tgactctcag ggtcagcatt cataatcgca ttctctcctt
     3961 ataaaattaa tttttagttt acgatagaaa aaaacgtggc actatagcca cgttaaaatg
     4021 gtatcacaaa gcaattttct ttgcaataaa aacaagtgta ctaaaactac ctacgaggtc
     4081 gtagcaattt tcttcttgtt ttcattttgc ttgtcttctt tgacgatttt gattatatag
     4141 gaaatgatcg tcttgcagat tgcgtaaaaa ggaacaccta agaagatacc aagcaatccg
     4201 gcaatatttc cagctactag aagaacgata atgatcgtta atggatggat tttcagtgat
     4261 ttcccaatta cattaggata aatgatattc ccatccaact gttggacgat tagcacaacc
     4321 acacaacaaa gtaatgcttt taccggatca ttgaagactg ttactagaaa tgcaggtgct
     4381 agtcctagat aaggtcctaa atatggaatt aggtttgtca atcccgcaat gaccccaaat
     4441 aagaaagcat aatccacacc aattaccata tatcctaaaa atgtgaaggt accaacgaat
     4501 aaacattcga ttgcttgtcc gctaatgtaa ttagccaatg ttttattcag ttgccccaat
     4561 aactccacaa tttggtttct tcttttttct gggaaaaact gttggatgtt tggcactagt
     4621 ttttctccgt ctttcaacat atagaacaag atgaatggtg ctgtaatgat tactacggtt
     4681 gccgaagcga tcgttccaac gatcgaacct aaactattgg atactccact aaggaattgc
     4741 tgaatgattg tcccgtaaga aatgtctaat tgctcaaaat atttattgat atctacttcc
     4801 ttgaacaaag gcaattcggc tacctctttt aaccagcttt ctacctgttt gatgaaatca
     4861 ggcatattag atgccaatga ggaaatttgc tgtactagac ttgggatgac actaagtaaa
     4921 atccaaataa ttgctgcaac taaaaggagc agcacaattg cgacagccca tattcttttg
     4981 atttttgctt tcatcaacag cttgacaata ggattcaata aatagtaaag aaagcctgca
     5041 atcagtacag gtgcaaataa cgtggaaaaa aatgtcccga tcggttcgaa aataaagttt
     5101 atttctgatg aaatcatgat caatgcagct atgatcaata attcaagcga ccaaaacatt
     5161 agtttagact gtctaagttt ttcaaacaat agatttcctc ctttctttct tactagtata
     5221 tattatattc gttaaaaatt cttttattct ttttttattt ttgaaaactt gccatacttt
     5281 ttatttgttt tattttccag tatactatac gaaaggaagg tggctagacc atgaaagttg
     5341 tacaaacaaa agatacaatg agcaatattt acttagatgc tgtacggatc aggcatcaag
     5401 tttttgtagt cgaacagggt gtgcctttgt ctcgagaaat agacaaagat gaagcccatt
     5461 gtatccactt cgtcctgtac tcagataaaa aagaaccgca aggaactgta cgtcttttgc
     5521 ctttagaaaa cggaaaaatg aaattacagc ggatggcgat tctttctgaa tacagacacc
     5581 aagggttagg aaaaatattg attgaagaag cagaaaactt tgctaagaat caaggctata
     5641 atacgatttt attaggggca cagtccacag ctgaaacttt ttacgaaaaa ctaggatata
     5701 cagcttacgg cgatcctttt gaagatgctg gcatgcctca tatttatatg aaaaagactt
     5761 tataaaaatt tatttcgaaa aaagcaaaaa acagcaagct tttgagaaaa atctctcact
     5821 ggcttactgt tcttttttgt gtttacttac gcgacaattg cttgtaacgg ttataccaaa
     5881 tatcaatata gccttccgag aacgggccat ctccattatt gatccagtca accagaatct
     5941 tcacattttc ttttaggatg aagtcaatat cgttcgggta attcatcatt ttgctgtgca
     6001 tctcatattc atcgacatcc aatagtcgtt tctcgccgtc aggaaatacc ttgatatcca
     6061 agtcatagtc gatatatttc aaggcctcat cgtccagcaa aaaaggtgaa gctagattac
     6121 aataatagga aacccccttt tctctgatca ttgctattac attgaaccag tattttttat
     6181 gaaaataaac aatcgctggt tcgcgcgtta cccatcggcg tccatcagat tcagtgacta
     6241 atgtgtgatc attcacgccg atcatagagt gttcgcttgt ttttaatacc atggtatctc
     6301 gccacgttcg atgcaatttg ccgtcgtgct tgtaactttg gatcgtcaca aactctcctt
     6361 cttttggaac tcccatagca acccttcctt aagcagcatt ttgtgctttg tgtttgggtg
     6421 ttcattacac cgacatcata attattatat caataaaaat gagctttgcc tagaaaggat
     6481 tcctattgtt tcgatttttc tctaactgat ctaccagttt catttggacc ttaggaaaaa
     6541 cgaccgaatc aaatgcatca ggcttcaacc acttcgaagt tttgttctcg gtaaattctt
     6601 gttctgctcc ctcggttgcc cgtccgtaaa aaaggagaac atgccatttc agatgactaa
     6661 aaatatgagt aacttctcct aaatgtcgtg tctgccaaac aaagagttcc tgcttttcaa
     6721 atgggagatt ttgctcttct tctgctacta ggtcatcaaa cagatcgatt tctggctttg
     6781 tttcccattc ttttttcaat cgctcatact cctcttgtgt cacttccatc attggaaatg
     6841 tccacatatt cgccagcaat ttttggctat ctctttcttc aaaataatac gctccagaat
     6901 gattttgaag agctgcactg atataataaa cgtcttttgg ctttgctttt tttgttttta
     6961 caggaaaact cgtttggatt cctcgtttgt tagctaaaca aaaggcttgg atcggacaag
     7021 tctcacactt tggagaagtt ggtgtacaga tagctgaacc tagatccatc attgcttggt
     7081 tgaattcacc tggatgcttt tcatcaatga ttttccgcat cgcttcatca aagattttcc
     7141 tgctagaagc ttttgcgatg tctgcttcaa tgcaaaacaa tctgctgact actcgcatca
     7201 cgttgccgtc aactgcaggt tctggaagtc caaatgcgat acttgcaatc gcgcctgtcg
     7261 tatatggtcc tattcccttc aatgagctaa tttcttcagg cgtttgcggc atttccccat
     7321 caaattctga catgatctgt ttagcagcag cttggatgtt ccgggctctt gagtaataac
     7381 caaggccctc ccatgctttt aaaagctttt cttctggagc atttgctagc tcttcaattg
     7441 taggaaacca ttccatgaaa cgataaaaat aatcgatcac tgtgtctact ctggtttgct
     7501 gaagcatgat ctcagagatc cagatacgat aaggatcacg attatagcgc caaggcaggt
     7561 ttcttttttc ttgttcatac cattgaatga actgatcttg aaattctttt gtttctttat
     7621 ctgtccattt ttcccattct ttattcactt tcctcttcct tttccgtaat gaatcgctgg
     7681 atcatatcca aatcaaatcc tttttgatat aagctttgct ttacttttag atttcttttt
     7741 ttaggttcaa accttaaatt tcttcgccat agtttatctc cttgtttgac taaataatca
     7801 tattctattt cttgatctgc ttcttgcgga agatcagcta tcgcttgttg gatcacttct
     7861 tgagaaaagc ctttcgtcat caatgtttgt tggatttttc tcaataattc tttttggctt
     7921 tttccgtgat tttttccaaa cgctttttcg gctgtctgat gtgcattttg aacttggtct
     7981 tcaaatgtat attggctgag cgcttgttca atgatttcag gtttcaaacc tttttgctgc
     8041 atctgctgcg ctaatttctt tggtcctttg tcacttaagc gcatattcgt gcgcacataa
     8101 ctttccccat agaccaaatc atcgacaagg tccaattctt ttaagcgggc tacgatttta
     8161 tttcgatctt cttgaaggat ttccttttct tttaagtatg ttcggatttc tttttccgat
     8221 cgcaactgat aacttaagta attcattgct aggtgaaaac cgaaatcagc tccgctactc
     8281 ttcttgatct cttggatagt ttcttcgtct aattcccgtc cttttaataa tcgatagcgt
     8341 actaatacat cttcagatac ttgtaaagct tctccttcag ataaatctac gcgatagaaa
     8401 gggcctttgc ctttactgat tctcgtaacg gttaacataa acatcctcct cgaacatata
     8461 ttctctatca taccacagaa aatccccgta atcaggtatt atatgttaga ataaaccaca
     8521 gaaaaaagaa aaagggagat acttatggca gaaacaattg tcaaaactgg acaaacggtt
     8581 cctttgaaaa tcaagcgttt aggcataaat ggtgaaggaa tcggttattt caaacggttg
     8641 atcatatttg ttccatatgc actaccaaaa gaagaagtac tagtgaaaat cacgaaagca
     8701 actcctcgct atgcagaagg agaattaata aaagtcaaaa aaacaagcaa agatcgcgta
     8761 gtggcaccat gtcctgttta ctatgaatgc ggtggctgtc aattacaaca cttagcttat
     8821 caagctcaat tggattttaa aaaggatctg cttttgcaag cattggaaaa attcaaacca
     8881 gcaggctttc gatcttatca acttttgccg acgatcggga tggatgagcc ttggcattat
     8941 agaaacaaag cacaatttca gttacgaaaa aataagcaga ctcaaaaaat tgaagctggt
     9001 ttatacgaag caaactctca tcagttagtc cctataacag actgcttggt tcaagaacct
     9061 cgaacacaaa aagtaatgaa tactgttgtt caactattga ataaatttga tgcacccatc
     9121 tatgatgaac ggacaaacag tggaatcttc cgcacaatca tggttagaat cggtgttaaa
     9181 actggggagt tacaagttgt ttttattact cgcagtaaaa aattcccgca aaaaaacgca
     9241 atgatccgtg agatcaatga acgactgccc gaagttgttt caatcatgca aaatgtccag
     9301 gcacaaaaaa cgtctctcgt gatgggggat gaaacgatcc acttatgggg aaaagaagcc
     9361 attgaagaac aaatcaatga agtgactttc gatctttctc ctcgtgcctt ctttcaactc
     9421 aatcctcagc agaccgaatt gctttatggc gaaggaatca aagcattaga tgtccagcct
     9481 aatgaaacga tcgtggatgc ttattgcgga gttgggacga tcggcttaag tgtagcaaaa
     9541 caagccaaag aagtacgggg aatggatacc gttcctcaag caatcgctga tgcaaaaaaa
     9601 aatgcggaaa gattaggata tcacaacact cgatatgaag tcgggacagc agagcaagtt
     9661 ctgcctaaat ggttgaatga aggttttcag cctgatggta tcatcgtaga tccaccacgt
     9721 acgggtttgg ataacgcatt gatccaatca ttattgaaat accctccaaa aaaacttgtt
     9781 tatatctcct gtaatgtttc tacacttgcc agagatctgg ttaatttaag taaaaagttc
     9841 aagattgaat atttacagtc cgtcgacatg tttcctcaga ctgcacgttg tgaagttgtc
     9901 gtgaagatga cgagactcgc tgactaaatg aaagaggttg tgaaaaagtc tgccctgtat
     9961 caagtaataa gaacagccaa acaaaaatag ctcttcatgt tttatgaata ctgtacttgt
    10021 gaccgaagag ttaacaggag gacactattt attaaaaaaa agggttgtga catagttttt
    10081 gtcacagccc tttttgatta ttattggata ttcacgtcta tcacttgata aaatgcattt
    10141 gtcgtatcgc tgatattcca tactgctaaa atcacattat atccttttcg atcctgcgga
    10201 agtgtgatcg tttggttgac tgtttttggt ggaacagttg ctttgtcgtc tatttttgtg
    10261 atcaattcaa aatcactaaa tttcaaaggt tgattaggat tccaagttgg tttggtaatg
    10321 tagtaatccc aagtacttgt ccgatgttgt gctgttaaat tccaagtaat atttaatgtt
    10381 cctggattaa ccatgttttt atgccatctg ttagatgtct gttcatctaa aggctcaaag
    10441 ccgctgactc ctgcactagc aatttttcca tcaatgaatg tatttttggt agcttcgata
    10501 ctttgcggtt cccattgtgc tcttccgaca ttttgattta agtttcctgc tgctgatgtt
    10561 cctaggtatg cacggcttcc tggagaagta atataaccat gcgcaaaacc tggaatgcta
    10621 aaaccgaaca accctaaact aactaaccca ataaacaata acgtactaat ctttttcatg
    10681 tagaaacctc cttcatttga taaccacatt gtaaacgctt tattgtatta acacaaacat
    10741 tatgctttta taattttatg ttgaagtaaa aaaggtgaaa aaagtaagat gcagattata
    10801 acagaagtag acgagaaaag tacaaataga aaacatgaga atcaaatcat atgatctttt
    10861 tcaaaaacat cattcatata aacaaatgtt caacttttta ataacaacaa ttatcaattt
    10921 ttttcttact tcacaaacta aatacaggtc ttgctgtgag ccttcatggt aaactaatat
    10981 tatagaaagg agttagtaaa atgaagatga taaaagatat tcgtttttgg gtttgtgtta
    11041 taggaattgt catattaggc tttttatcag ggttgcttag cggaaatccc ggaaaatatt
    11101 actattcttt gcaacttcca ccatttgcac cacctagctg gatatttggg ccgatgtgga
    11161 ccttactgta tatattgatg ggtatttctc tttatttgtt acttaatcac aacaacaaaa
    11221 aacagcgaaa caatcttgtc ggtctttttg tgattcagtt catttttaat tttatatggt
    11281 ctgctctatt ttttaattta agaaatattt tcattgcagc aatcgatatt acacttttag
    11341 ttattttctt gtcagtgctt atgtatcagt tgtggctgca tcatcgcctg gcaatgtggc
    11401 tcatgattcc ttattattta tgggtactat tcgcaactct attgaattat tcaatttatt
    11461 ttttaaacta agcgctaaaa agagacgtcc tgtaatttaa cacatagaaa aagtgccacc
    11521 taagttagat tttttgtcta atttaggtgg cactctttat taaccaaact atttttttct
    11581 agtacccact tgttgttcca tactcattat tctggtcata accataacca ttttgttcct
    11641 gtccagcgta aggatcataa ctttgagtat cttgacttgg tgtatagtac tgacttgtat
    11701 cttctgtttg ctgataatag gtattcggat cttggtactg atcatatgtg ttttctgaat
    11761 aggaagaata atcggtgtac ccttcactat tcgatccatc accgtttgtc gaatcgccat
    11821 cttccgaatc atcaaagaac atcattgaag cattctcatt tttcaaatta ggtaatgtat
    11881 cgcttgtttt tatatttaat tgtttcttca gttcattttg gatcgaaaga agatcatttt
    11941 ttcctaaaat ttgatagtag atatcattga tcatttgtcc ttcgccttgc aactggtctt
    12001 gtttgattgt ttcaaacgcc ggggtgtagt tcgtcgctac atcaagcatg tcatcccaat
    12061 ctaagtccgt cgtcacattg ttctcaactg cttttaaaat ttttctataa ttgcttacgc
    12121 catctaaact taaaacttta ttgacgattt tcgtcactac ttcccgctga cgacgttgtc
    12181 gaccgatatc gccttctgga tcttcgtgtc gcattcgaga ataggctaaa cctttttctc
    12241 cattcaatgt ttgttcacct actggtacat ggacaccatc caaagtaaag tcaattttat
    12301 tattcacttt gatgccaccg accgcattga tcaaatcttc catgccatcc aaattgatcg
    12361 ttacataatg atcaatagga atatcgagca gttgctcaat tgaatccatg gccatttcga
    12421 caccaccaaa tgcgtaggca tgatttaatt tatctaccgt tccataacct acgatattcg
    12481 tataaatatc tcggtccaaa ctgatgatcg ttgatttttt ttgtttcgga ttaactgtta
    12541 ctaccatcat cgtatcagaa cgtccttgtt ccgttcttcc taatccaccg gtatctaaac
    12601 ctaatagcaa aaccgaaaaa ggttctttgt catcaatgct tactctctca gaacgtttgg
    12661 aggatattcg attagagttt ttagaaattt tgtttactgt ttggctcgct tctcccataa
    12721 atctgattcc gtatgctgat aatccggcaa tcagcaaaac gaatacccct aacaaggtta
    12781 atagaacttt ttgccatcgc ttcataatac acctctgttt cacattttct aaaatattgt
    12841 ctcatataac tgttcaatca gcaaattcac tttttaatca taagaaaact ttaaaaaaca
    12901 tttttgtgta acgattatta ttttttaaaa tttctcaaaa ttcttaacta tcataccata
    12961 ccgtgaaaaa gatcgaaaga ccgaatacac gcagttcgca atcgttttat ctttttttat
    13021 gtattttttc cagaaaaagc gaacaacaag gtattttcca aataatcgtg cagtaaaatg
    13081 atcgcacata cctttcccat ctttttaaca gtctttgcct accgttcaga ttatcattcg
    13141 atttcacgac aatttcttcc tatgactggt ccttttgtta aacccatctt ctattcgttt
    13201 tatttccagc tcactgcatg gctcttaaaa tgactcgaac tagtgattgc attaccatca
    13261 tcttttaatg gatagatatg ctcctcttca aagtaaaacg attttctttt aaagtaatag
    13321 aattgacatg gtaatgagta tgtatactag tggtttcaca aatggtcttt tattcaacat
    13381 ccaaaaactg aaatttcttt aaaatccatt actaacgaag aaaatgttcc ttgcttgata
    13441 attagttagg acatgtcaag tgaacaaatg catttactta gccaaaaa
//
LOCUS       DARPZF010000064        13429 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.067, whole genome shotgun sequence.
ACCESSION   DARPZF010000064 DARPZF010000000
VERSION     DARPZF010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13429
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.067"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..914)
                     /locus_tag="SLE65_002380"
     CDS             complement(<1..914)
                     /locus_tag="SLE65_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HEI8449641.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1342..1905
                     /gene="efp"
                     /locus_tag="SLE65_002381"
     CDS             1342..1905
                     /gene="efp"
                     /locus_tag="SLE65_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEI8449642.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            2006..2176
                     /locus_tag="SLE65_002382"
     CDS             2006..2176
                     /locus_tag="SLE65_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449643.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            2391..3650
                     /gene="lysA"
                     /locus_tag="SLE65_002383"
     CDS             2391..3650
                     /gene="lysA"
                     /locus_tag="SLE65_002383"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEI8449644.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            3637..4437
                     /gene="dapF"
                     /locus_tag="SLE65_002384"
     CDS             3637..4437
                     /gene="dapF"
                     /locus_tag="SLE65_002384"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HEI8449645.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            4440..5321
                     /locus_tag="SLE65_002385"
     CDS             4440..5321
                     /locus_tag="SLE65_002385"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEI8449646.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            5318..6034
                     /locus_tag="SLE65_002386"
     CDS             5318..6034
                     /locus_tag="SLE65_002386"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEI8449647.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            6040..6735
                     /gene="dapD"
                     /locus_tag="SLE65_002387"
     CDS             6040..6735
                     /gene="dapD"
                     /locus_tag="SLE65_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEI8449648.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            6751..7752
                     /locus_tag="SLE65_002388"
     CDS             6751..7752
                     /locus_tag="SLE65_002388"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEI8449649.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEKPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            7749..9110
                     /locus_tag="SLE65_002389"
     CDS             7749..9110
                     /locus_tag="SLE65_002389"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEI8449650.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            9070..10221
                     /locus_tag="SLE65_002390"
     CDS             9070..10221
                     /locus_tag="SLE65_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HEI8449651.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            10196..11365
                     /locus_tag="SLE65_002391"
     CDS             10196..11365
                     /locus_tag="SLE65_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEI8449652.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            11540..12919
                     /locus_tag="SLE65_002392"
     CDS             11540..12919
                     /locus_tag="SLE65_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEI8449653.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            13200..13429
                     /locus_tag="SLE65_002393"
                     /pseudo
     CDS             13200..13429
                     /locus_tag="SLE65_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4485 a         2339 c         2923 g         3682 t
ORIGIN      
        1 aagtaaatgt tttttgataa atagcggtct gctgcgtctg gaaaaatcgt aacgacacga
       61 tgaccaggtg gtaaacgacg aatttctctt aatgctgctg caaaagccgc accactcgaa
      121 cttccaacta atagtccttg ttctcgtgct aactgcctag tatagttaaa cccttctaca
      181 tcagagattg tctcgatctg attgattgaa aggggagaaa gaaacggcgg aatgaattct
      241 acaccgatac cctcaatttc gtgaggggct ggatcaccac catttaacac agagccctct
      301 ggttctacac cgattattcg aatgtcggga tatttttctt tcaaaaaggt agaagttcca
      361 gcaaaggttc caccactccc aattcctgct acaaaactat ggatattttc tttgatttca
      421 tgaaagattt ctggccctaa cgtatgatag taagcagcag gattatcttt attttcaaat
      481 tgaagaggca gatagctgtt tgatatctcc tctgcaagtt ttttactttt gctgatggca
      541 ccgatgattc cttgctcact aggagaatgg atgatctttg ctcccaatgc tttcatcaat
      601 tgttgttttt ctaagctaaa cttctctgga acaacaaaaa ccgttcttaa tttgtatgtg
      661 agtgcggcca gagcgatccc aattcctgta tttccggcag ttggttcgat gatcgtcgtt
      721 ttttcattga tttttccttg ggcaaatcct tctttgatca aataactgcc caatctatct
      781 ttgatacttc ctccaggatt taaatattct agttttgcat aaatagcaga acctttaggc
      841 atagaatagt gctgattgtc aaagcgataa agcggtgtgg aaccaatagc ttctgtaatt
      901 gtcgagataa tcatgtgggc ctcctaaaaa aagataataa aaaaaggagc tgactattaa
      961 atcagctcct tgaaagacat agagaaaaat tgagtagata aaaagataag ttacctggta
     1021 ctcattctat gaagggcaat taatagacat gacaaatagt atgctgcttt tatgcaccat
     1081 acaacagcaa cgattcaatt gtttttggtt gctgactgtc atgtgtatcc ctccaagtaa
     1141 aatttttatt aacgatagca tgaaaaaaaa taaaagtcaa aggcttgaaa gaaaaaaata
     1201 tttcgatagc atcgtttacc cgtgtttatt tttctgacaa ataggcatga gaccttaaaa
     1261 gatagagaat actctagttt tctggccggt tgtctgatac aataaagttg attatgataa
     1321 agaaaagaag gagcaaaaat aatgatctca gcaagtgatt taagagccgg tatgactttc
     1381 gtacaagacg gcaaactgat taaagttctg gatgcaagcc accataaacc tggtaaagga
     1441 aatacagtta tgcgtatgaa actgaaagat gtccgttcag gtgcaacata cgacacaacg
     1501 ttcagaccag aagaaaaatt tgaaaaagca catatcgaca caaaacctgt acaatatttg
     1561 tacacgatgg atgatacagc tttcttcatg gatttggaaa catatgagca atatgaaatt
     1621 cctgtagaaa cagtagaaga agaaatgaaa tatatcctag aaaacatgga agtaaaaatc
     1681 caatttttcg gtagcgaagt catcggcgtt caattaccaa caactgtcgt attacgtgtt
     1741 gtggaaacac aaccttccat caaaggtgca acagtcactg gttcaggtaa gccagcgaca
     1801 atggaaactg gcttagtagt caatgttcct gacttcatcg aaacagatga attgttggaa
     1861 atcaatacag cagaaggttc ttatgtaaaa cgtgcgtcaa aataattcgc taacggattg
     1921 ataagaattt gaaaacagag cttgacctct tgaaaggcag atcatcggat ctgcctttca
     1981 agaggttttt tgtggaatca gcaaattgaa aaataaaaaa gtatttgatt ttatttatat
     2041 tttgaaagat gaatggcaaa agctagagaa agaaaaaact gcacttattt atgaagaaat
     2101 tgaaatgatt cataaaattg aaaatatccg aactattccg aactatattg aagcgaaaat
     2161 attttttcat cactaaatag tgttgaattt atgtttttat gtataaatag cttctaatag
     2221 ttcgggtatt ttgtttttat aaccattttt attcttattt ttaaaaaaat atttcgaaat
     2281 atactagaca attcagaaaa ttttgtttaa tattattcca ataaaattca aatctttatc
     2341 aaatgaaatt ccaataaaaa cggaaaaaaa gtgaaaagag gaatgaaaaa atgacagaat
     2401 tgataattgg cggagtcaca gcaagcacat tggcagaaaa gtataagaca cctctgtatg
     2461 tgtatgatga agaaaagatg agacaaacga tgctgtcatt caagcgaggc tttgtatcga
     2521 aacgttttga tacaaaagtg ctttacgcct ctaaagcatt ccaaacgatt gagatgctgc
     2581 atttagttcg tgaatatgga ttcgggctag atgttgtcag tggtggggaa atctataccg
     2641 ctttgcaagc tgattttcct agagatacta tctacttcca tggtaacaac aagacgccag
     2701 aggaactgat ctatgcactt gaaaatgatt tgttgcatat tgttgccgat aatttgatgg
     2761 aagttgaatt attagcagaa ttaagccaac gctatttaaa aaaaatctgt atcatgcttc
     2821 ggttgaatgt cggagtagaa gcacatactc atgaatatat cgtcactgcg catattgatt
     2881 caaaattcgg catgagctat gaaagtaaag agtgccaaca agcccttcag ttgataaaag
     2941 aaagcagcta tctagagtta gaaggatttc atgctcatat cgggtcacaa atttttgatg
     3001 ttactgcttg gttagctgaa atcgacaaat tgacgaatta cttaaccgat tttgaccaac
     3061 ctctttcctt gaatcttggc ggagggtttg ggattcgtta tacacaaaat gatcagccga
     3121 tcccagtcga agaggcacta aaaaaactga ttgaatatac ggaagaagct ttggaaaaac
     3181 gaaaactgac cattcgtcaa ttactgatcg aaccgggtag aagtattgtt ggagaagctg
     3241 gtacaacact atacacgatt ggtttcatca aaaagacacc acataaaaaa tattactttg
     3301 tagatggcgg gatgacagat aatatccgtc cagctctgta tcaggcagaa tacgattgtg
     3361 atttagcagc aaaactgtcg gaagaaaaaa cagagaaagt gacgattgca ggaaaaatgt
     3421 gtgaatcagg cgatgtggta attaaagaag cttatttgcc gaaagcagaa tcgggtgatc
     3481 ttttagctgt ttattccacg ggagcttatg gatactcgat gagcagcaac tacaatcgag
     3541 cgacacgacc agcagttgtt tttgtcaata atggccaatc aagactgatt gttcgcagac
     3601 aagcattttc tgatctacta aggggggaag tttcctatga tccttcataa atataatggc
     3661 tgcggaaatg attttatctt attagattac gcagaagaca cagattatag tcaattagcc
     3721 gcttctttat gcacaaaaga aaaatatgat atagacggat tgatcgccgt aaaaatcgat
     3781 ccgttggaaa tgatctatta caacaaagat ggcagccgcg cgccgatgtg cggaaatggc
     3841 attcgctgtt ttgctcgata cgtaaatgat cagaacatga tgaatgaaca ggaattcaac
     3901 gtagagacat tagcaggcac aagaaaaatt acggtgttgg atccctcacc tttttattgc
     3961 agcgtagata tgggagtgcc agatgattct ccggaaaaaa tcaaagctaa tcaaacttat
     4021 ccaataaaaa accaggaaat agagatcaat ggtgaaaaag taacgatcac tagtttattt
     4081 ttaggaacga ttcataccgt tgtttttgtt gaaaatgcgc gtgaggaagt ctggagaaaa
     4141 agaggtgaac tgatctgtca tcatcctttg ttcaaagaaa aaaccaatgt caactttgta
     4201 gaagtagtca atgaacaaga attgatcgtc cgtacctatg aaagaggagt aggttggaca
     4261 cttgcttgcg gtacaggttg ctgtgcctct tatgtggttg ctaaggaaac tgggaaaatt
     4321 tcagcagatc aggtagttgt tcacttggaa caaggagact tgatgatctc tggtgaggat
     4381 gcgatacaaa tggctggccc agcagttcat gaatggacaa gaatattgga ggaatgaaga
     4441 tgataaaagg ttcgatcgtg gcgctgatca cgccgatgaa tgaagaggga tcagtagatt
     4501 atgctggttt ggaaaaattg atccaattcc atttagatga acaaacagat ggattattag
     4561 ttttaggtac aacaggagaa tcttctacgc tcacacaatc tgaggaggag cagatccttc
     4621 aactgacagt aaagaaagtg gctggccgtg tgccggtgat tgcaggagct ggaacgaata
     4681 atacgaaaga aacgattgaa aaagcgaagc attttgcttc tttgggggca gacgcacttt
     4741 tggtcatcac cccttactac aacaaaacaa gtgatgcagg actagctgct cattttacag
     4801 caattgcaga agcctcaccg attccgctta ttttgtataa tgttccttct agaacaggca
     4861 tgtcgattcc aatccatgta ttagtaaatt tagcagaaca tcctaatatc attggtttga
     4921 aagaagcctc aggagatatg gcttatgtga tggatgccgc tcggttgatt ggagaagaat
     4981 tcttccttta cagtggaaat gatgatttga tcctaccagt aatgagtgta ggaggaagcg
     5041 gtgtaataag tgtatgggcg aatatccaac ctaaaatagt ccatgaatta gtaaaagata
     5101 cgcaggacgg aagatggcag caagcaaaag aaaagcaatt aaatgcactt gaactgatcc
     5161 atgccttgtt cagtgagacc aatcctattc ctgtcaaagc agccatgtca ttattagact
     5221 taccttccgg acctctacgc ctgcctttag tttctctttc aaaagagaaa aagaaacaat
     5281 tagctcagct tttgttaaaa gaaaggacgg ttgaaaaatg aaaatcggac tgattggcag
     5341 tggacagatg ggaaatagag tcgaagaagt tgcacaagaa agaggagata cggtccttct
     5401 tttacggacg gcacctaaag aagcaactac gcttgctttt acggaactgc cagaactgct
     5461 tattgatttt tctcatccag ataatttaga gaaaatcctt tcgtatagct tatcatatca
     5521 acttccgtta gtcattggca cgacaggtta tacacaatca cagttccaag aaataaaaga
     5581 acatgccaaa catgtacctg tgatgtatag tgctaatttt tcgttcggca tcatggtgat
     5641 gaatcaacta atcaagcaag cagctgcaat gttgcaaggc tggcagatcg aactgattga
     5701 aaaacatcat agtcgtaaaa aagatgcacc atctggtact gcaaatatgc tgcttcaaac
     5761 aatccaagaa gtgcaaaagc tgcagcccgt atacaactgg caagggaaaa aaagagaaga
     5821 aaaccaaatt ggtgtacaca gtattcgtgc aggttcttta cctggtgaac atgatgtatt
     5881 gtttgctgct actgatgaaa tatttacgat caaacatgaa tctttttcta atcgaatctt
     5941 tgctgcaggc gcagtagaag cagcggactg gttgaaagat cagtcaccag gttattacaa
     6001 attagaagat ttattaatgg acaaaggggt gtaaaaaacg tggaagctca agaaatcatc
     6061 cgctacattc aaacggcatc taaaaagacg cctgtgaaag tctatctgaa tgtaaccgag
     6121 ccaatcgaat ttaaagaaag taaagttttt ggtgaaggaa gcagcttcgt tgtttttggt
     6181 gactatgaga cgattgctcc ggttttagaa gctgaatcag aaaaaatcat tgaaatcgaa
     6241 atcgaaactg ctgcaagata cagcgcagtt cctttgctag atattaaaaa aattaatgct
     6301 cgtatcgaac caggtgctat tatcagagat caagtgtcaa tcggcaacaa tgccgtgatc
     6361 atgatgggag cgattatcaa tattggtgca gtaatcggtg aaaacacgat gattgatatg
     6421 ggtgctgtct taggtggacg agcgacagtg ggcaaaaact gccatattgg tgcaggagct
     6481 gtcttagcag gtgtgatcga accagcatcg gccaaaccgg ttatcgtaga agacggcgta
     6541 ctggtaggtg cgaatgcagt gattgttgaa ggtgtccata tcggaaaaga tgcagtcgtg
     6601 gcagcaggag cagtggtttt agaagatgtg gcagcagaaa ctgttgtcgg tggaatacct
     6661 gcacgtgtat taaaaataag tgatgatcag acaaaagaaa atacagcatt gattgctgcg
     6721 ttacgcgaat tatagaggag atggagaaaa atgcgcgaaa tagatacctg tattgtgggg
     6781 gcaaccggat tagtcggcca aacgatgctc aaagtgttag aagaatatga ttttccagta
     6841 ggacgattga aattattagc ttcaaaacgt tcagccggta aagtttgtgt attcaagaaa
     6901 aagaaacaca ctgtacagga attgacagaa acttcatttg aaggatatga tttagcgcta
     6961 ttttctgcag gtgcttctgt atccaaagag tttgcgccaa tcgcacgaag tcagggacta
     7021 tttgtcatag ataattcctc agcatggcgg gaagattcgg atattccatt aatcgttcca
     7081 gaggtcaatc tggaagacta tacattgaat cggctgattg caaatccaaa ttgttcaacc
     7141 attcaagcgg tacttccgct taaagcttta caagaagcct ttggtatcca gcgagtcaat
     7201 tattcgacct atcaagcagt ttctggttcc gggcaaaaag gcattgaaga tcttcatcgt
     7261 acgcaaaatg acgagaaacc agttttgtat ccttataata ttagccaaac ggtgattccg
     7321 gaaatcgatc agcctttgga aaatgggtat acaaaagaag aacagaaaat gataaatgag
     7381 acccgtaaga ttctgcatca gcctgctttg ccagtatcag caacctgcgt acgtgtgcca
     7441 atcgaaaatg gacatggagt ctctgtggca gttcaactgc aaaaagagtt tacgacggaa
     7501 gaaattagag agtgtctcag ccagtttcca gggattcaat tagaagatga tctagcagca
     7561 cataaatatc cgacgagcat tcttgctaga ggaacagata tggtttatgt tgggaggatc
     7621 agaaaagaca cttctttaga gaacggattg ttgttctata cgactgccga taacatacgc
     7681 aaaggagccg ctgcgaatgc cgtacagatt gctgcagctt taatgcagaa aatagcggag
     7741 gtggcaagat gagtaatacg ctgaaagtag cgaaattcgg cggaacatcg atgtctcatg
     7801 aagagcaatt caaaaaagtc cgtacaattg ttctttcaga tcccaatcgc caagtgatcg
     7861 ttgtttctgc tttaggcaaa cgtacgtcag atgatgacaa agtaacagac ttactttatt
     7921 tgatttatgc ttaccttcag catcatgttg attggacacc cctttggaaa aggatttgtg
     7981 atcgtttcat tcaagtaaga gatgttcttg ccctgcagtt acctattgaa gatgaactag
     8041 cacgcataca gaaacaactg gaagacgaaa agataactga agattattta gtaagtagag
     8101 gtgaatatct gactgctcaa ctgatggctg agtatcttgg ttaccagttt attgacgcaa
     8161 aagacctgat tttctttgac tatgatggga aaatcgatca ggaaaaaaca gcacaggaaa
     8221 tcacaaaagc atttaaaaga tatccgaaaa tggttgttcc agggttttac ggggcgaacc
     8281 ctgcaggaaa agaaaaatta ttgggccgtg ggggaagcga cattaccggc gcgatactgg
     8341 cgaagatgtt gcaagcggaa agttatgaga attggacgga tgtttcagga atcatgatgg
     8401 ctgatccgcg aatcatcgat catcctaaaa tcatcgagga aatctctttt agagaactga
     8461 gagagatggc ttatatgggg gctaacgttc ttcatgaagc agctgttttc ccagttcaag
     8521 aggctgatat ccccatccaa ataaaaaata ccaatgatcc tttcgctcaa gggacaaaaa
     8581 tatcgaatca cgaaatagaa aaggaaaatg gactgacagg aatagctgga cgcaaggatt
     8641 ttctttccat cactttattc aaacgtcata tgtccgatga aatcgggttt atctggaaag
     8701 caatgagcat ttttgctaaa catgagatat caatcgaaca tattccttca gggatcgaca
     8761 atatcggagt gatcgtctca gcagaagcga ttgccgataa gttatttctc atcacgaaag
     8821 aattaaaaga aacacttggc gtggaagaaa tcgtcgtgat cgaagactta gctttgatct
     8881 ctgtcgttgg gggtccgcat aaagaattga ttggattatc tgggaaagtg ttatcgatat
     8941 tgaacaaatt agaaattcgc acatcgatct tatcacaagg agcacaggag ttgaatctga
     9001 tcatcggtgt accgaataat caatatgaaa cagtagtgaa gggtatctat gaagggatgg
     9061 tgaatacgga tgctgaaaga atatcgaatg gcactccatc aaattcctga aatcgggttt
     9121 catgaattca agacaaaaaa atatttatat gaacaagtaa aaaacagcga ggccgttatc
     9181 catgaaatcg gcgaaacagg actactcctt tattttgata atcagcaaga agaaacgatt
     9241 gcttttcgaa cagatatcga tgcactgcca gtcaaagaag aaacgaatct ctcttttgct
     9301 tctaagcatg aaggttatat gcatgcatgt ggtcatgacg gacatatggc gatgctttta
     9361 gggttgactg actttataac taaacacatt gaggatctta tttataatgt agtactgatc
     9421 tatcagccat cagaagaaat ttccggtggc gcacaaagcg ttattcagtc aggattgttg
     9481 gataaatatg aagtacaagc aatatttggc tttcatctat ggcctggact agctaaggga
     9541 gaagttttct ctcgaccagg acctttgatg gcacaaagca gtgaaacaga cattatcatt
     9601 aaaggccagt ctgcacatat tgcttctagt gaaaaaggaa tcgatagtct ggaggcagct
     9661 gtacgatttt tgaagaatgt ttatgatttt gaccggcaat taccggcaga gtggaatcat
     9721 ctaatgaaat ttggccaaat ccaaggtgga acgatccgaa atgttttagc tggagaagtt
     9781 attgtatccg gaagtatccg ttcttacagt tcagatatgc aaaattattt gaagagggga
     9841 ttagaccatt tagcagaaca gtttcactct acagctacta tttcttttcg ctataatgac
     9901 ggctatccag ctgtaatcaa ccatagaggc ttatatgcag cactgttaga ttcaaacaaa
     9961 ctacatgaat tagatgctcc agttcttcaa gccgaagatt ttggcatata tacgcaacaa
    10021 tatccatgtg tatttttctt tttaggtgtc ggtgataccc ctgctttaca tgatccgacg
    10081 ttcgattttg atatggatgt tttagaaaat ggtgtagaat ggtacaaaac gattcttttt
    10141 acagaaaatc ttcttgtaaa aatcgatagc agttcaaaag aggagcgagt aaataatgat
    10201 gaatttatcc aatcgattta gtcctaggct ttctagaata gaagtatcaa aaatacgaca
    10261 attcgatcag caaatatcgt cgataccaga tgtgatcaaa ctcaccctgg gagaaccgga
    10321 ttttccaact cctgaacatg tcaagcaagc aggaatagca gcgattgaag aagacttttc
    10381 tcactatacc ggaatgagag gattagagga actgcgggaa gcggcttgta tatttcagca
    10441 acagcgttat ggattaactt atgatccgca aacggaagtt ttgacgacag ttggtgcaac
    10501 ggaagcgatt gcctctgcgt tgttatctgt tttggaagaa ggagacaagg ttcttattcc
    10561 agcgcctgct tattcaggat atcagccatt agtggaacta gctggtgctg aattgatccc
    10621 gatagatact tctgacacag ggtttgtctg tcagccggaa caatttgaac gagcatttga
    10681 acaatatgga tcagctgtca aagcagtcat tttaaactat cctaacaatc ctactgggac
    10741 gacattgtct gcaaaacaat tgaaagcaat cgctgaggtt ttaaaaaaat atccggtatt
    10801 tgttataagt gatgaagtat atgctgaatt gacttatagt ggaacgcata tgtccatagc
    10861 tacttatctt ccagaacaaa caatcgtgat aagcgggtta tccaagtcac atgcgatgac
    10921 tggttggcga gtgggcttta tttttgctca aaaagccctt attgacgaac taattaaagt
    10981 ccatcaatat ctggtgactg ccgctacaac gatgtcgcaa aaagctgcgg ctgaagcgct
    11041 aataaatggg gtgaaagata gcgagaatat gaaagagcaa tatcaaacac gaagagacta
    11101 tctggtccag caattggcgc ctttaggatt tgaagtgacc cagccaaacg gtgcatttta
    11161 cttgttttgc aaactcccag ctgccattca aactgactct tggcagtttt gtgtagaatt
    11221 agcggaacag gcaaaagttg cgtgtatccc aggaattgca tttggcccag aaggagaagg
    11281 ttatatccgg atttcttatg ctagcagcat ggaaaaatta catgaggcct gcaaacggat
    11341 caaagacttt ttaacagaac agtgattcat agattttatc aaaaaaacaa tcgttaattt
    11401 tgcggtatat tctgcaagga gacgattgtt ttttaaattt agttcaaatg aacgcgtttc
    11461 ttttgattca taactaatgt aatgttaagt ttaaattgtt tagaatgatt ttaaaagaat
    11521 attcaaggag gtttcatcaa tggaaaaaat caaagttgtc attgtaggtg catctcatgg
    11581 agggcatcaa tcgatcttgg aactattgac acgatacggt gaaaatgtag atatcacgct
    11641 atttgaagca ggagactata tttccttcat gtcatgtggt atggagctgt atttagaaga
    11701 caaggtaaca gatgtaaatg atgtacgtaa tttcagacca gaaaactttc cgcaatccaa
    11761 tgttcatatt ttaaataatc acgaagtaaa aacgatcgat gccgataaaa aaacagtaac
    11821 ggttactagc gcatcagata acgaaacaaa agaatatcct tatgacaaat tgattttgag
    11881 ttctggtgtc aaaccaaaca atctgccagt accaggagca gatctagaaa atgtctactt
    11941 gatgcgtgga tacaattggg caaccaaaat caaagaaaaa ttaaatgatc cggctattaa
    12001 aaaaatcgct gtcgtaggtg cgggttacat tgggatcgaa gcagcagaag caagccgaaa
    12061 agctgggaaa gaagtcgtat tgcttgatgt gatcgataga cctttaggca cttatttaga
    12121 tgctgagatg acagatattt tagaacaaca cctaaatgaa aacggtattg aagttttgac
    12181 aaatgcaaaa atcgaagctt ttactggtaa cggaaaagtt gaggcaatca aaacaagtga
    12241 aaaagaaatc ccagcagatc tagtcattca agctgccggt gtgaaggcaa atacagaatg
    12301 gttaaaaggg atcgtcgact tagatgaacg tggctggatc caaacaaatg aatacttgca
    12361 aacgaatctt ccagatgtgt atgcagtagg agatgctaca cttgcttatt ctatcccagc
    12421 acgcaaaaaa atgccgatcg ctttagcgac tgttgcacgt agagaagcac gttatgtagt
    12481 aaaacatctt tttgaagaag taccaaacaa accgttcggc ggagtcgtag gttcctctgc
    12541 attaagtgtc tttgactatc attttgcagc aagcggattg aatagcttta cagcagcaaa
    12601 agcaggagta gatgtacgag tgtcttatta tgaagatacg ttacgaccaa aatatgtacc
    12661 agaagaacaa ggaaatccaa aagtgtccat ccaattattc tcggatccaa tgacccatca
    12721 attgctagga ggagcagtat tatctaccta tgatgttaca ggtcaaggaa atgtattggc
    12781 actagcgatc caaaacaaac tgactttaga agaactagca gaagctgact tcttcttcca
    12841 gccaggcttt gaccgacaat ggagcatgtt gaatctagcc gctcaacaag cgttaggaga
    12901 agaaccattt gtagaataag aaaacgaaat atttgaaaag aggttgtgaa aaagctgcct
    12961 tgcatcaagt aataagaaca gccaagtaaa aacagcttct tatgttttta acttggctgg
    13021 acttattacc gcagatgcaa gcttttgaac accgtttatt ttcaaaaaag ggactgtgac
    13081 acgatttgtg taccgacccc caaaagttag accaaaaaat ctaacttttg gaggtcggta
    13141 ttttttatgg ttaaatatac ttttgaactt aaattaaaga tcgttcatga ttatttggat
    13201 ggcaaaggcg attggaccgt aaaaatccag atcaagagat tgaagcggaa atgcttaaaa
    13261 ttcgggagaa gcacaaggat tatggctgtt tacggatgac caatgaacta agaaaccgcg
    13321 gtttctctat caataaaaag aaagttcagc gcttgatcaa gaagctagga ataaaagtaa
    13381 cggcatacac gcgtaaatca cgtcgctaca attcttatcg aggaaaagt
//
LOCUS       DARPZF010000065        13049 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.068, whole genome shotgun sequence.
ACCESSION   DARPZF010000065 DARPZF010000000
VERSION     DARPZF010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13049
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.068"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(77..149)
                     /locus_tag="SLE65_002394"
     tRNA            complement(77..149)
                     /locus_tag="SLE65_002394"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="SLE65_002395"
     CDS             530..1099
                     /locus_tag="SLE65_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEI8449654.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="SLE65_002396"
     CDS             1086..1946
                     /locus_tag="SLE65_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEI8449655.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="SLE65_002397"
     CDS             2136..2840
                     /locus_tag="SLE65_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8449656.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="SLE65_002398"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="SLE65_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HEI8449657.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="SLE65_002399"
     CDS             4677..5993
                     /locus_tag="SLE65_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449658.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="SLE65_002400"
     CDS             5994..6863
                     /locus_tag="SLE65_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HEI8449659.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="SLE65_002401"
     CDS             6918..7727
                     /locus_tag="SLE65_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEI8449660.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="SLE65_002402"
     CDS             complement(7830..8459)
                     /locus_tag="SLE65_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HEI8449661.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="SLE65_002403"
     CDS             8629..9921
                     /locus_tag="SLE65_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8449662.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="SLE65_002404"
     CDS             complement(9997..10659)
                     /locus_tag="SLE65_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEI8449663.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /gene="groES"
                     /locus_tag="SLE65_002405"
     CDS             10884..11168
                     /gene="groES"
                     /locus_tag="SLE65_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEI8449664.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="SLE65_002406"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="SLE65_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEI8449665.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4338 a         2254 c         2824 g         3633 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    13021 tgtttagagc gtgagacaaa agtgttctt
//
LOCUS       DARPZF010000066        12597 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.069, whole genome shotgun sequence.
ACCESSION   DARPZF010000066 DARPZF010000000
VERSION     DARPZF010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.069"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(10..159)
                     /locus_tag="SLE65_002407"
     CDS             complement(10..159)
                     /locus_tag="SLE65_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449666.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            555..755
                     /locus_tag="SLE65_002408"
     CDS             555..755
                     /locus_tag="SLE65_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEI8449667.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            1323..1886
                     /locus_tag="SLE65_002409"
     CDS             1323..1886
                     /locus_tag="SLE65_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449668.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1947..2291)
                     /locus_tag="SLE65_002410"
     CDS             complement(1947..2291)
                     /locus_tag="SLE65_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449669.1"
                     /translation="MISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFHYSPYRLF
                     QYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHDEVYLAEC
                     LANLEQKGIYLT"
     gene            complement(2388..2633)
                     /locus_tag="SLE65_002411"
     CDS             complement(2388..2633)
                     /locus_tag="SLE65_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8449670.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(2703..2957)
                     /locus_tag="SLE65_002412"
     CDS             complement(2703..2957)
                     /locus_tag="SLE65_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449671.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(3121..3444)
                     /locus_tag="SLE65_002413"
     CDS             complement(3121..3444)
                     /locus_tag="SLE65_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449672.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            3631..3704
                     /locus_tag="SLE65_002414"
     tRNA            3631..3704
                     /locus_tag="SLE65_002414"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3665..3667,aa:Ile,seq:cat)
     gene            complement(4089..4586)
                     /locus_tag="SLE65_002415"
     CDS             complement(4089..4586)
                     /locus_tag="SLE65_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEI8449673.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(4626..5435)
                     /locus_tag="SLE65_002416"
     CDS             complement(4626..5435)
                     /locus_tag="SLE65_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEI8449674.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIDMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            5769..6626
                     /locus_tag="SLE65_002417"
     CDS             5769..6626
                     /locus_tag="SLE65_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEI8449675.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            6619..7521
                     /locus_tag="SLE65_002418"
     CDS             6619..7521
                     /locus_tag="SLE65_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEI8449676.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            7554..7904
                     /locus_tag="SLE65_002419"
     CDS             7554..7904
                     /locus_tag="SLE65_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HEI8449677.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7953..8876
                     /locus_tag="SLE65_002420"
     CDS             7953..8876
                     /locus_tag="SLE65_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEI8449678.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            8954..9847
                     /locus_tag="SLE65_002421"
     CDS             8954..9847
                     /locus_tag="SLE65_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8449679.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9885..10448
                     /gene="amaP"
                     /locus_tag="SLE65_002422"
     CDS             9885..10448
                     /gene="amaP"
                     /locus_tag="SLE65_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEI8449680.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            10462..10650
                     /locus_tag="SLE65_002423"
     CDS             10462..10650
                     /locus_tag="SLE65_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEI8449681.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            10663..11565
                     /locus_tag="SLE65_002424"
     CDS             10663..11565
                     /locus_tag="SLE65_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEI8449682.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            11597..11839
                     /locus_tag="SLE65_002425"
     CDS             11597..11839
                     /locus_tag="SLE65_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEI8449683.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(12095..12466)
                     /locus_tag="SLE65_002426"
     CDS             complement(12095..12466)
                     /locus_tag="SLE65_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449684.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4461 a         2113 c         2366 g         3657 t
ORIGIN      
        1 ttccactcct tatgcagatt tttttaattc ttgcactgct tgttcgatcg taacacctgt
       61 cgctacatga ttggtatttt ctttgtcaaa aacgacaaat agattcaaat ctgtatccaa
      121 ggttactcga tattgtatat ctttgttata gaatgtcata gccattctcc tttctttaaa
      181 tacttgctga aaggcaacga acgcgttgat aacgaaattc catttataag tataccacca
      241 attgaaaggt tttcatagtt aagaaatttt aaagtcaaaa gttgcagata aaagcaaata
      301 aacaagaaaa caaaaagtga atcaatcgcg gttattcaac tttttcttcg attcgaagac
      361 aatagaagac aatgaatttt atatttcatt gcattatcct tgtgttatta gaaaaagcat
      421 gatatattaa atgagtaatc tattttgaaa cgtaatttga gcgatatatc tacatagata
      481 aaactccttt tgcctatcaa atatttattg caacgaaaaa acgtacattg atacgtatca
      541 ggaggaattt atttatgaat aacggtacag taaaatggtt caacgcagac aaaggttttg
      601 gctttatcac tggtgaagat ggaaatgatg tatttgcaca tttttcagct atccaaggtg
      661 acggcttcaa aactttagaa gaaggccaag cagtgtctta cgatgttgaa gatggtcaac
      721 gtggccctca agcaacaaac attgttaaag cttaataaaa attgactttt aaccgtcttt
      781 tcgaaagaaa agacggtttt tttgtacgaa aaaattcatt ggtcgttgaa tgggctgaat
      841 agtagtgtat aaaacaattt tgtggagcgt gaagctttta tggtagagga aaatacgaat
      901 aaagtgatgt tgataaaaag attcctatct tgaatatgaa tcgagatgtc ttgaaaatga
      961 atgagtttga ccaatcatta tcctatcgaa atttacagtt tcgttcgatt ggtctgtcaa
     1021 ttaatgaaaa agtaaaaaag aatatgttct aggaagaggg cggcacatct aaatttttaa
     1081 gtaacggaca gttcaaatat caagcattga aagaggctat cctactgttt gaaggaatac
     1141 gaatatataa aaacgacaaa gaggaaaaag tagttcatta aatcccttca agtgatgaaa
     1201 gaatgagatc taataaaacc tgatctttca tctgtttttt taataacgta ataatttttt
     1261 tattttttgt gctttcgccg ttattgtaga gtgatttagc attcttattt ttaaaaataa
     1321 ctgtgttata tattaaaaaa ggcataatag ttataagctt ttttaaagaa tatttagaaa
     1381 ttattaattt tcgtctgaaa acaaaaaaag aaagcgttat tattttagtc tattttcagg
     1441 gggggaacct tatgataaaa aaactatttt tactatcaat attaacgcta gcaatggcag
     1501 gttgttctga ctctggctta gcaactgaac tgatcacaaa atcaactgaa gccacgacag
     1561 aggagttaaa atgtggaaac gatcacagtg actacagagg cttaaatcga cgatgcatgg
     1621 gaatattagg cagaagcaat tgtaagcatc gatgtagtaa tcgaagaagg tgtagaagaa
     1681 gcaacagaaa aatcaaaaga aagatcaaaa gaagcaatct gtgctgtgca tcgtatacag
     1741 acgtcgaaga tgcggtactt ttaaaccacg tcaggagatg ttcatttatg tctagggaag
     1801 ttggcgatga accaaaacta gagtacgctt ttagttttgc acgtgaggat gaagataacc
     1861 ctaaaactta cgacatttta gcttgatcta agatggttaa agctttttaa tgaagtaaga
     1921 ggagatagaa ggcttttcta gttatattag gtaagataaa ttcctttttg ctccaaattt
     1981 gctaaacatt ctgctagata aacttcatcg tgttccggat aaatcggcac gttgcgctct
     2041 acagtaggta aatcaaaaaa tgcttcgcat gatttgccac gatacatagg atttttccac
     2101 tctggtgctg ggctgtaacc acgtttttcc atttcatcca tgacaagctg atgatattgg
     2161 aataatctat aaggagaata gtgaaaaaca taatccacag tagcatgttt ctttccccag
     2221 ccatttcctc ttaatgcaca gcattcccga tgttgtccta aaagctgttg acgaggaagc
     2281 tttgaaatca atttttcatg ccataatcac atagaaatgt ctcctttata tatagattgt
     2341 taaccttaga cgttaaatga aaaaaccagc accaaggctg gaaaaaatca cttcagtttg
     2401 cttgctgttt ctgagcgacc aattaggtaa tcaacggaaa tatcgtaaaa gtcagcgata
     2461 tagattaatt caatgatgct tggaatttct tctccttctt cgtacttacg atatttgaat
     2521 aaaggaatac ttaacgcgct agaaacagct acttgagata aagatcggcc agttcttaag
     2581 aaattcagac gacaacgtaa agtatccagt aaaatagctt cttcgatact catttaatca
     2641 cctttcatta tagtagaata gttataatga ctatagaaag ctacacatgc aatcaatagt
     2701 actcaatgtt ttttatttaa acgtatcaaa taaagaatga cgatcaataa agacaaaacc
     2761 agtcctgata attcttctat aaaaacacta tcgggttcaa agtagttgta attaaaaact
     2821 ttccacataa agtagatagc cggaagagtc aaaatagcta aataaaaccg ttctttgttc
     2881 caattcataa gataaacaat acttgcgacc agtgcgaccg caggcaccca aaacaaaact
     2941 ctcaccaacg taatcatgta acggactcct caacgattca tataataaaa gataacatgt
     3001 tattgcatac atcacaaatg aaatgctagg aaaataaaag aagaatagat caatgaaaaa
     3061 tgaaaaagca gaacagtttt ctgctgataa gcaggaactg ttccgctgaa tgtgtcttat
     3121 ctatcgagaa aaaatcaatg gattgatatc taagtaattc aatacatata aaaagaggac
     3181 gatcgcattc actaaaaagg aaagaatgat gatcccatag cgaatggaaa catatttaac
     3241 aaatactttt gtttgaatac gggcatatct ttttccttta tagctgagca tcatgacaag
     3301 aagcaaaagg gtaatcacac cttgaaaaat cattccaata aacagaattc ctgaggtttg
     3361 ataatttaat tggagaaaat aagctgctgc cgcaactaaa tcgaataaaa tcgcaataaa
     3421 tggcaaaata atcactccta acattgagaa taaataaaag aataacattt tttctaaaat
     3481 aagcaaataa aaattaaagt aacaaaatag ttatgacaca agtaaaagaa ataagaataa
     3541 caatattatt ttacttatat tttgaaactt gtgagagttt gtcattcgtg ctatagttga
     3601 aaagtaacaa aaataaattt tatttatgat gtacctttag ctcagttggt tagagcagac
     3661 ggctcataac cgtccggtcg taggttcgag tcctacaagg tacataagag gttgtgaaaa
     3721 agctgccctg catcaagtaa taagaacagc caagtaaaaa cagcttctta tgtttttact
     3781 tggctgttct tattactgca gatgcaagct tttgaatacc gtttaaggaa gaggttgtga
     3841 aatcagcgtt ttgacctgag tattagctta acaaacggaa aaatagttcc tcatattttg
     3901 ccgtttgtta agctaatacc gagggtcagc tgattgaaca ccatttaaga aagaggtcgt
     3961 gagcctgccg tttcactctg tgtcataaaa aagccaatct actttgatag aaaaagcacg
     4021 taggactaaa acagttctgc gtgctttttt tattgtgtgt taaatatcgt aaatgaagat
     4081 agatattttt atgattcgac gatagagacg ttgaaatctt tcaacagctc taaagcggat
     4141 tctccgtgtt ttctactgga gactaacatt ggatcaacaa aaaagtctgc ttcaggaaaa
     4201 gcactctgca ggcctatcag attagagagt acacacaagt ttgtttcaat cccgactact
     4261 tcgatctctt tttgttcttc tttgctttca aataaagttt cctggatttc agctaaagtt
     4321 tcaggtggaa tcgtaaagta atacttttta atcactcgtt cattttcttg tggagaaaga
     4381 agagggatca attgcaaatc ttctcgttct tcttctttgt ccttcagttc aactggtata
     4441 tcccgtgtga agagaatata ttcattattt tggcgtgctt tagctaatct ttgagcaata
     4501 cgttctgcca attgatctga ctctggaata taaaattcgc tgtttggatc aagaatatga
     4561 ttttgcatat caataataac taacattttc tttcctccta cattcatatc gtcattttat
     4621 tctttttaat agaagttttt taaaatataa gcaacaccag cttcttcatt cgtcagtgtt
     4681 acttggtttg caatttcttt tacttgtcgc tgtgcattcc ccatcgcaat actcaacccg
     4741 ctgtaattca acatatcaat gtcgttttct tgatcgccaa aagccatgat gtcactcgat
     4801 tcgattccaa ggtaatccgc cagaaaaaca agtgaatgag ctttagtgat acctgtaggc
     4861 gtgatttcta agaaatgcgg atcagagaat actgattgga taccatctgc ttgcagatct
     4921 ctttgtagct tctgtagttt ttcttcactc ttatctgtta atgctaattt aagatagcta
     4981 agagaaggat cttccaacat atttaaaatt tgatcaaaag aatggttctg taaattgaaa
     5041 tgttcataat aagggtcatc tttgactaga tttgattcat cgaatgtcag ctgatcatct
     5101 tgggtttctc ggctagcaat gatggatatt ttcgcttctt gagcatagaa gaaggctttt
     5161 ctcagtgtat cgctatctat ttttgaacgt ctgagaactt tcgccatttt tccatccttc
     5221 atttcagcaa tcagtgaacc attggaagaa atcaaatagc caccgattcc taattcggaa
     5281 aaaatatctt tagcagaaat gctgttcctt ccggtagcga cggttacgat tccgccattt
     5341 tcatcaaatt tccgaagtgc ttggatattt tcttctggta tctttccatt tcgatcaagc
     5401 aaggtaccgt ctaaatcaat cgctgctagt ttcattttat cttcctactt tctttttaca
     5461 tatctatttt cctgttacct taagattaaa tgagaattta aaaaaatgaa actaacttgc
     5521 tttgtcatta tgaatttttt caaaaaacat tcttaagaaa aaggtggcta tatatagtag
     5581 tttttggtca atacctttga ataaaaagcc atgaaaaacg aatagttagc gcttaccgat
     5641 gcgttttgtg ataaaaaaat tttaaaatat tcaatgaaaa caaagcatat attttgcttt
     5701 aaaaccaaat gaggaatatt ctagatgtag aacaggttag aaaaagatta gaaaaaggag
     5761 tgattttgat ggagaagaga tacggcgtag ttcctgtggt aactgcttca gacgaaaatt
     5821 atgctcctta cttgagcgtg atgatcgcaa ctgcattaga aaattgcaat aaaacaagac
     5881 gcataaaatt ttatgtgatt gacgatggtc tatcagaata tagtaaagaa ggattggaag
     5941 aaacggtaaa taaatattca agtaatgcaa gtatccaatt cctgacagtg gaaaaagata
     6001 tctacgaaga cttcctagtc agtgaccata tcacaactac cgcttactta agaatttctt
     6061 taccaaactt attagctaaa gaggattata agaaagtcct ttacttagat tcagatgtgt
     6121 tagtactaga cgatatcgta aaactatatg atgagccgtt aaatggaaaa acaatcggcg
     6181 ctattatcga tccaggccaa gtgaaagctt tggaaagatt aggaatcgat tccgatgact
     6241 tgtacttcaa ttcaggagtg atggtgattg acattgatca atggaataaa aaagaaatta
     6301 cagaaaaaac tatccattac ctcagtgaaa atggcgatcg aatcatctat cacgaccaag
     6361 atgctttgaa tgctgtactt tatgaagatt gggaacaact tcatccaaaa tggaacatgc
     6421 agacttcgct gatttttgaa cgtcatccag caccaaatga aaaatatgaa cgtcagtata
     6481 aagaaggaaa tgaaaaacct tcgatcgttc actttacagg acatgataaa ccttggaata
     6541 cgttgaaaga tcatccgtat accaatttat acttaaaaaa attagcacac agtactctaa
     6601 cgaaagtagg cgagatcaat gaataaaaaa gaaatagcag tagtcgcaag ttgtaacaca
     6661 aaattcgtac cacatttagc tgcattattt gtctcagtat tagataattg caacccgtct
     6721 aaatttgttc ggttctatgt gattgacgat gatatcgatt ttgaaagtaa acagctttta
     6781 cgcttctcag tgaaaaacgc acgaatgaac tcagatgtgg aattcttgaa aatcaataaa
     6841 gaattcttta caaatgtggt aatcagcgat cgtattccag aaacagctta ttatcgtatt
     6901 gcgattccgg aattgttccg cggcacagaa gttgaacgta tcttatatat ggattgcgac
     6961 atgatcgctt tacaagatat ctctaaatta tggcgtcttg acttcggtga ttcaatcgta
     7021 gcagctgttg aagacgctgg gttccatcaa cgactggaaa aaatgaaaat ttcagctaaa
     7081 tcaatgcgtt atttcaactc aggtttgatg ctgatcaatg tgaaaaaatg gttagatgaa
     7141 aatattacgc aaaaagtatt agatttcatc gaacataatc cagaaaaatt acgattccat
     7201 gaccaagatg cattaaatgc tatcttacat gaccgttggt taccacttca tccgcgttgg
     7261 aatgcacaag gctatatcat ggcaaaagca aaaaaacatc caacagcagc aggtgaacgt
     7321 gaatacgaag aaactcgcaa caatccttac attatccatt tttcaggaca tgtgaaaccg
     7381 tggagcaagg attttgaagg gccaacgaag aaatattacg aaaaatatgc agggatgacg
     7441 gctttccgtt gtgtagctaa attccctaaa tatccaaaat atgcaaaagt tcaaccaaaa
     7501 acagatgtag ttgttaaata atagaagaca acaactgaag agggggagta ggaatggaaa
     7561 ttacaatgtc taaaaatgca gtagagacgt taattgaaaa ggttggggaa aatacaaaaa
     7621 tcgcactcgc gcttatcaat gattccgatc catttctaag ggacaaaggt gcttttgcaa
     7681 aaggcagctt ttttcaaatc attccttttg tttcggaatt tggagaatat gcgactaaaa
     7741 tcgagcatcc attattggac atctatacat ctaaattaga gcaaaattat ttcggtaaac
     7801 gattgaacat ggacttcaac aaacagcttg acagcttttc attagaaaat gaaatcgcag
     7861 tactcgatta taatatcaaa ttaaagaact gcttcttcag ctaatagttt cgagaaagtc
     7921 caaaaaggag gtatacattg agatactact ttgtggatga agaaaagaat gtaatagaaa
     7981 cagatgaaaa aaaatataat tggctcgtac ttgatagtgc aaagcccgaa gagattgagc
     8041 aagcaatcga agaattcgag cttcctgatg atattttcgt aggaaccgaa tatccggaag
     8101 aagtttctcg gatggagcgc ctttatgaga cgaaactaga gcatccattt tctttggtag
     8161 tgattaatct agatcagtca gataatcgta tcgaaaaaaa attaacgcca atatcttttg
     8221 tactttccga taatctcttg attacttgta tcgatagaaa aaccgaattt gtggatcggc
     8281 tgctgacaaa gcatggaaat catttaaact cgtttgaaaa gatcatcacg tatacattat
     8341 tagatattta cacccattac gtgaaagaac taagagagat gaaaaagcga attgacgctt
     8401 tggataaagc agctcgtaaa acaacggaaa atgaagaact gtataaacag gcagatcttg
     8461 aaagagacat cgtatatatc gatcatacct taagagatca acgggaaaca atggatcaat
     8521 tatggaattc tgaaactttc atcaaacgtt tagacgatga acagctactc tatgatgtcc
     8581 atttgagaca gcgacaaaca gaaaaaatga tcgagatcta tcgagattta ttagagagta
     8641 ttggtgatct attcaacggg atgatggaca ataatctaaa tcatatcatg aaatatctag
     8701 attcagctgc attaatcatt tccgttccgg cgttgttcgc agggatttgg ggaatgaata
     8761 caggaggatt accgggtaaa agttctgctc taggctttat actcgtagtc tttggctctt
     8821 tgatagcagc agtagtttta ggttaccatt tataccggaa agattataca aattaaagaa
     8881 tctatttaaa acaggtatca aacaaagaaa tttgttttgg caatacaatt taaaaactag
     8941 gaggaataca gcaatgacag aaccaaaatt aatcgacccg cgaaacttgt accatacgga
     9001 gaaatttcct aaacaagatc aggatacacc agctttacag cagaatatga ttcctgttcc
     9061 tgattgtgga gaagaatcct atgaaggcaa taatcaacta gaaaaccgcc gtgtactaat
     9121 cactggtgga gattcaggga tcggtcgtgc agcagcgatt gcatttgcta gagaaggggc
     9181 agatatcgct cttcaattct tcccaggaga agaaaaagat gcagaggaag tagcaaaata
     9241 cgtgaaagtt gcaggacgta agattgtctt actacctttt gatcttcgtg acgaacaagc
     9301 acctaaagaa atcatagata aagccgtgag tgaacttggc gggctagata cgatggtact
     9361 aaacgcagga cagcaaattt cttgtcagtc tattgctgag ttaccacttg agcaagtcaa
     9421 agacacattt atgataaaca tcatcgctat gtttgcttta gtgaaagaag ctgttccgca
     9481 tatcccagca ggaggagcaa tcgtaacaac aacttctgtt caagcattca atccaagcga
     9541 acatttatta gattacgcag caacaaaagc ttcaatcgct aactttacga tcggtttagc
     9601 aaaacagctt gcacctaaag gaatccgtgt aaatggtgta gcacctggtc caatctggac
     9661 accattacaa ctagacgaag gacaaccttc tgattcgatc cctgaatttg gtcagcaaag
     9721 tttactagaa cgtgcaggtc agccaggaga attagcacca gtttatgttt tcttagcatc
     9781 gaataaagca agttatgtta cagcccaaat ttacggagta actggtggag aagcgatcaa
     9841 cttataagaa gttgatcgtt tcacccctat gaggaggtgc gaaaatgaat aaaggtgtaa
     9901 aaacgatcgg agtgatcgga acattacttt tgctatctgt gcttttgttt gcgatactat
     9961 taagtgcaac ctatccattg ccttttcagc tagagaagtt tcgattcttt tccatcacta
    10021 attcatacgt gcaacaatat gtattttggc ttgccgttgc atttgctatt ttgacaatta
    10081 tcacgttact tgttttcctg ttttatccaa aaacaatcgg aaactttcta ctgaaacatg
    10141 gtgatgggga gttgacgttg gataaaaaag caattgaagg aatggttcgt tctcacttgc
    10201 atgaagatga attcatccat tcaccaaaag taaatgtcaa agcaacgaaa aacaagatcg
    10261 ccgtcaatgt aaaaggggag ttgaaacgaa cttcagcact cattggtaaa acaggaacat
    10321 tgatgaaaga aatcgaaaat gaagtacaac acatattggg aacaaaagag ccagtgaaag
    10381 tatcggtgaa atacacaggc tttgaagaac cagctaaacg aagcaatgac cgcaaacgag
    10441 tagaataggg ggggaccaaa aatgaaagaa ctattttcga catacaagct ccctatcatc
    10501 tttggggtac ttggattgat attagccgtt ttatggatca ccgtgggctt tttcaagacc
    10561 ttattgatct tgatcatggc agcgatcggc gtcgctatcg gtttttatct gaaacaaacg
    10621 aaaatcttag atcactattt taaatcttag gaggaaacat ccatgaataa caataacaaa
    10681 aataataaca ataaaatgaa caaccaaaaa ccagtgtctg cacatccaga cccaacgaca
    10741 ccaaaccaat caaatggtgt gaacgatgaa aagaacaaaa cagcaccagt atctgcacat
    10801 ccagatccag tagtccctaa cgttcaacaa ggagtagaag agaagaaaca tgatgcagaa
    10861 aagcatgcac ctcatcatcc aggaactcca gaatctaaag ttccagaaca acatgatgca
    10921 atcgatcctt ctaaacctgt ggaagagcaa aaacatcctt ctgaccatgc gaaagcacaa
    10981 gaaaaactta gttctgacca cacaaacgga caaggaaaac ttggttctga tcatacaaat
    11041 aaccaaggaa agcatgattc tgaacaggaa gattcaatgc gcggtgagct gaattatgaa
    11101 gataaagttg tgcaaaaaat catcggaatc gcaattgaac aagtagacgg tttattatct
    11161 gcaaacggtg gtttcttctc taatgtggca ggaaaacttg tgaatacaga taatgtaacg
    11221 gctgggatcg aaacagaagt cggtaaaaaa caagtagcag ttgatatgga tgtcattgtg
    11281 gaatatggca aagatatcga aaaaatcttt gaagaaatgc aagaagtaat cggcaaagaa
    11341 gtaaaaaata tgacacattt agaagtgatc gaagtcaacg ctaacgtagt ggacatcaaa
    11401 acaaaagaag aatttgaaaa agatcaagaa acggtgcaag acaaagtaac tgacgcagcg
    11461 aaaaaaaccg gtgaatttgc ttcgaatcaa acagataaag taaaatcagc agctggaagc
    11521 ggcgcacaaa aagtaaaaga aaatacagaa ccacgggttc agtaataagg aagtaaaaca
    11581 ttaggaggaa cgaaacatgg gatttatttg gtcacttatc gtcggaggaa ttatcggagc
    11641 aattgcagga gcaatcacga ataaaggttc ttcgatgggg attattgcaa atgtcgtagc
    11701 aggtttagtt ggatcagcac ttggtcaagc attattaggt tcttggggac caagtattgc
    11761 aggaatggca atcgtgccat cattgattgg tgccatcatt ttagtactaa tcgtatcatt
    11821 ctttgctcga aaactgtaaa aagactttta aaaagaggtc gtgaaaaagc tgttcttcat
    11881 caagtaataa gaacagccaa acaaaaatag cttctcatat ttttcatttg gttgggcata
    11941 ttatcgaaga tgcaagcttt tgaacactgt ttatacggaa taagaggctg tgacaagact
    12001 tttgtcacag cctcttattt atgcgggcaa attcccaatt agatttttaa aagtttttcc
    12061 ttaaatgtgt ctttattgat acagagaagc ttctttaata aaacaatgcc tccctaaatt
    12121 ttcttgagat aggaaaggtg aacatacaaa ataatacgac cactttgaaa acccagatga
    12181 tccacaaatg gatcgtatga tactgatgaa gtaaaaagca atggatcaga aactcaaaga
    12241 gattgaaaaa gacaaggaag aaataatatc tcttttttac tcttgtctgt tttagccaat
    12301 aatagctcgt aaagtaatct agacaaacaa atagaagtaa acaaagtttc gtaagagcag
    12361 caatcgtatc atgttgctct gctagacgat tgacgagcag gaaaaatgtt ggtaatggaa
    12421 tatagatcac gagtaatgaa agaaaaaagt aaacaataaa tggcatacta ttcctcctaa
    12481 ttgtgtgagt tcgccctcat tttaaaataa cgatatttgt ttgtgaagct ttttcgtgtc
    12541 gtaacaaatg ttatctaatg tatttttaaa taaataatca ttattatcaa aataatg
//
LOCUS       DARPZF010000067        12526 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.070, whole genome shotgun sequence.
ACCESSION   DARPZF010000067 DARPZF010000000
VERSION     DARPZF010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.070"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..191)
                     /locus_tag="SLE65_002427"
     CDS             complement(<1..191)
                     /locus_tag="SLE65_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449685.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(201..1016)
                     /locus_tag="SLE65_002428"
     CDS             complement(201..1016)
                     /locus_tag="SLE65_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEI8449686.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1278..1721)
                     /locus_tag="SLE65_002429"
     CDS             complement(1278..1721)
                     /locus_tag="SLE65_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HEI8449687.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1855..2193)
                     /locus_tag="SLE65_002430"
     CDS             complement(1855..2193)
                     /locus_tag="SLE65_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEI8449688.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2181..2558)
                     /locus_tag="SLE65_002431"
     CDS             complement(2181..2558)
                     /locus_tag="SLE65_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEI8449689.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2782..3975
                     /locus_tag="SLE65_002432"
     CDS             2782..3975
                     /locus_tag="SLE65_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8449690.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4141..4563)
                     /locus_tag="SLE65_002433"
     CDS             complement(4141..4563)
                     /locus_tag="SLE65_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8449691.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            4958..5152
                     /locus_tag="SLE65_002434"
     CDS             4958..5152
                     /locus_tag="SLE65_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449692.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            5149..5643
                     /locus_tag="SLE65_002435"
     CDS             5149..5643
                     /locus_tag="SLE65_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449693.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(5805..6977)
                     /locus_tag="SLE65_002436"
     CDS             complement(5805..6977)
                     /locus_tag="SLE65_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEI8449694.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(7183..7998)
                     /locus_tag="SLE65_002437"
     CDS             complement(7183..7998)
                     /locus_tag="SLE65_002437"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEI8449695.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNMI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(8148..8594)
                     /locus_tag="SLE65_002438"
     CDS             complement(8148..8594)
                     /locus_tag="SLE65_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HEI8449696.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(8591..9595)
                     /locus_tag="SLE65_002439"
     CDS             complement(8591..9595)
                     /locus_tag="SLE65_002439"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEI8449697.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(9635..9964)
                     /locus_tag="SLE65_002440"
     CDS             complement(9635..9964)
                     /locus_tag="SLE65_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HEI8449698.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(10090..12417)
                     /locus_tag="SLE65_002441"
     CDS             complement(10090..12417)
                     /locus_tag="SLE65_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEI8449699.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         3542 a         2440 c         2281 g         4263 t
ORIGIN      
        1 atgcaacctg gaccaataaa aagtaaagaa aaaataaagg aaaagacatt ccttccatct
       61 atcgacaaaa ggaacgcagc tgctatatac aagatattga cacaccaaaa acaaaggcta
      121 cttgccaatg attgatacaa ccaataaaag aattccatat aaacattttt gtcaaaacgc
      181 tgctctttca taatcacctc ctattccttc attcctgatg aagcgatccc ttctacaaaa
      241 tatttttgca tcgctaaaaa tataaaagca acaggaagaa cagaaacaac tgaggcagcc
      301 atgattaatg cgtactctgc atcaaatagc ccaataaaca ttttcaaccc taactggatt
      361 gttttatttt ccgtagaaga caaataaatg aatggcccca tataatcgtt ccatgtatta
      421 acgaatgtga tgatcgtcaa actggcaatc gccggttttg taagaggtaa aatgatcttg
      481 cgatagattc cccactctga taagccatcg atccgcgcac tctcacataa agaatctggg
      541 atactactgt agtattgctt caacaagaac acaccaaaag cattgaacgc ttgtaatagc
      601 accaacgacc acaacgtata tgttaaaccc acttttctca tcataatgaa ctgcgggatc
      661 atataagact gccaagggac agcaatcgtg ccgatatatg ctaaaaataa aatatcgcgc
      721 cctttaaaat ttagtttaga aaacccgtaa gcagcaaaac tagaagtaaa caactgaatc
      781 aacgtgatca caacgcttaa aaaagctgta ttcttaaaaa atgtcactaa aggaatacga
      841 gaccaaataa ccagataatt ctctaaatgc caagttttag ggatccattg aatcggaatc
      901 gtgaacactt cattatttgc tttgaatgaa gcagaaacca tccataaaaa aggaatgatc
      961 gtcaataaag ctaatacaat cagcagaatc atacccaacc attgaataaa gggcatgttt
     1021 tttgaacgaa tttttgcttt ttttctttca tttcgaacac ctccaaagtt ataatcttca
     1081 tttctttgta atgattacaa tccagaacaa cggttattat agctgattca tttccgttct
     1141 tcttatgttt gtaagcgctt atttaacaag ttatgtaaat ctctttattt tttttgattt
     1201 aaaaatgaaa aaatacaaaa gcaagactgt catacgtctc gcttttgtat tgaaatttct
     1261 tcgattagag atacttatta ctgttcaaaa gcttctttga aacggtgaat caattcattg
     1321 actacaggtg ataaaatccg attctttttc cagactagca tgcagttcgt ttcaatcatt
     1381 gggtcaagcg gaacgaatgt cactcgcttt gaaagatgac ttacagcacc ttctatgact
     1441 aaagcagcac ctacctgatt ctcaattagc gcaaatacat tgaaaatcaa attgtacgtt
     1501 cctgtgatca gcaactgctc cttttttatg cctaaccagt cagcaaacat tcgctgtatt
     1561 tctggacgct ttgagatcaa aagaggtaca ttcgcaaagt cttcttttgt tatcacgtct
     1621 ttttttgcta aaacagaatt ttctaaaatg agcaatcccc atttttcctt tcttggtaac
     1681 aaaatcgttt cgtatttctc tgtatctact ggatctagca aaatcgctaa atctaacagg
     1741 cttttttcta gtcactccgt gatatcatca cttgttccgc tgtggatatg aaattgaacg
     1801 ctgggataat cacggatcaa cttttctagt aatagtgcca atgtattcga attatcagct
     1861 tccacacagc cgatcgtaaa tcggccgctg aataattgtt tttttctgtt ctcgaattct
     1921 tgagtggttt gattcgttaa atctaaaatt tcttctgctc ggctttttta gaaaataacc
     1981 tgcttctgtc aagatcattt tgcggttttc gcgtacaaac agttctgttc ctagttcctc
     2041 ttctaactcc ttcagttgtc ggcttaaggt tggttgtgta agatgtagaa cttctgcggc
     2101 ttgagagatt gttccttctt ctgcaattgt ccaaaaatat tttagtaagc gtaactccat
     2161 agcgatgctc cttgattttt ttacttgata cattccattt tatttctaga taacacacga
     2221 tcatatttct tgatttttcc ttgtaaacgt tccaaacact cttgcatttc agcaatttct
     2281 ttcgtcaaaa gttcactttc ttcaatcaaa agcttacgcc gctcaaatac agttgcttct
     2341 ccttcgctag ataggcgaat atattcaatc aaagactcga tcgataatcc ggcatttcgc
     2401 atacagatcg taaagtcgac ccattttagg tcttcttctg tataatcacg gattccgcct
     2461 tttgtccgat taactggtgg aatcaacccg attcgttcat aatagcgcaa tgtatcggcc
     2521 gaaatgccct tttcttcact gacttgtttg atattcatct gatcactctt tctcttaatt
     2581 tcttgccact ttacttatgt attttattta ttctacaact ttaagtgtac tccaagtcaa
     2641 tactcatttc tattaaaact aagctggatt atctatatcg gttgtttgtg tattatttca
     2701 aataaaaaag tcttgttttt ttattctttt ttggatatac ttttaacaat ttagggaaat
     2761 tttaggaaaa ggggtataaa aatgacaacg tatcagcgaa aggtattatt atcgacatcg
     2821 gcgggaattg ctttagagaa tatggatatt atgtttttag ctttttcatt atcttcaatg
     2881 attacttctt ttcatattag tggtacgcaa gcgggtttca tttcaacgat cactaatttg
     2941 gggatgctca ttggaggtat tttttttggc atcatagctg ataaatatgg acgtgtgaaa
     3001 gtattttctc aaacggtcct tctgttttcg attgcttctt tattgatgta ttttgcttca
     3061 aacatctact tggtttatct ctttcgcttt atcgcaggtg taggagcggg aggagaatac
     3121 ggggcgtgta tgtccttgat ttccgaaagt ttttcaaaaa aacaaattgg acgagcttct
     3181 tcggttgctg gtattggtgc gcaggtcggt gcggctttgg ctgcgatttt agctgctgtg
     3241 atcattccaa cgtttggttg gaagatgttg tatgtcgtag gtgtactgcc ggtgttgatg
     3301 gtcttgttca ttcgtcgcgg cttgactgaa ccaaaggaat tcaaatctgt acaatctgcc
     3361 gaaaagaaaa ccaaacttag cagactgttt gaatcaaaac atcttgcttg gcaaacatgt
     3421 ggccttagta tcatggtaac tgtccaaatt gccggctatt ttgggttaat gaattggctg
     3481 ccttcaatta tgcaaaatcg attagggctt tcggtttctg ggtcttcatt gtggatggtc
     3541 agtactattt taggcatgtc tttggggatg atgacttttg gcataatcat ggataaattg
     3601 gggcctaaac tagccttttc tttgttttta atttgttcat ccttatctgt ctatctactt
     3661 gtgttagccc atagccagtg gagtttggta gcagccgctg tgatagtcgg ctactttatc
     3721 aatggcatgt atggtggata tggcgcagtg attagtagtt tgtatccaac agaaatccgc
     3781 gcgacggcga ataatttcat tatgaacctt ggacgagctg ttggtggttt ttcttctatc
     3841 gtcatcggtt tcttgatgga tcattatagt ttaactgccg taatcttgtt tttgagcggt
     3901 atttacctag tcagtctgct ggtcttgaca actcttactg gtgttacagc attaagggaa
     3961 agcttgcagc attgatagtt gagtctgtaa atgacaagaa agaggtgtgg caaaagcttg
     4021 catctgcggt aataagacca gccaaatcaa aaacatgaga cactgtttcc gtttggctgg
     4081 tcgtattact tgatgcaggg cagctttttc aactgctaat ttccttctat ctggcggcga
     4141 ctattctttg acgtccgtca tttcaaagta ctttactaat aacttagcat aacgaaaaac
     4201 tgtggataca ctcgtatatt gagcgtctgc ataatcttcc aaatttttct caggatgttg
     4261 atacatgaat tcaatcaaat gataattata tgattttctg tagaaatgaa gataaataat
     4321 gtagattggg aagttctcct gcttttccat agaaaagcgc cgattattct cattcttcaa
     4381 aatgacctta tcaggatatt tttggaacaa ttcttctaaa tctgttagat aattcaagat
     4441 agacttactt gataccttca attcgttttg tagttcttct attgaacacc aacgttctgt
     4501 ttcaagcagt aaatgaatca ttttaatttt cttttgagaa acttttgtta aaaaagtctg
     4561 catattttct cctcctgtat ctactttact atactacata caagaaaaaa aacggataca
     4621 aatatcatat tgtcacaccg tcaatagtgc ataaacctgt tattatttct ctttttttcc
     4681 taagtattct attgatatga atcatttaat cgtttattat ataaatgtca ataatctaat
     4741 aataaaataa cgtacatatt ttattattgc atacttaata acagaactat agcaaaaaat
     4801 cccgtgtatc aacacgggat tagattaagt ttcctcaatc actattcata acacaattat
     4861 tataacaagt aagtaaacaa ttgaaaagga catttattga aaacggttgt tttttactta
     4921 aggaggaaat ttagcgaaaa aattagttgc attgtttttg gtcgcaggaa gtttgttgag
     4981 tgggtgtggt gctactacgt ctactactca aagcacaagt tcagatcagg cttccagcag
     5041 cagtaccacg atctccgaaa gtacggcaga ttcatcgaaa gaacaagaac aaattgaaaa
     5101 gaaaaaagaa gagaaacaaa aagcggaaaa agctgcacta gaaaaaaagt gacagaagcg
     5161 gaatctgctt tgtcacaagc tgaagcaaat cctacaaaag aaaactatgc aactgcttca
     5221 gcagctatcc aagcgctacc tgaaaacaaa caagagttga caagccgtct tgctgcaatt
     5281 gattccacaa tcaaagcaaa agaagcagaa gaagaacgga aaaagcaaga agaaattgca
     5341 cgacaacaag cagaacaagc gcaacaagaa gcaatcgcac agcaacaagc agaacaggcg
     5401 aggcaagaag caatcgcaca gcaacaagca gaacaggcgc gacagcaatc agcagctgaa
     5461 caggcctctc agcaggcaca agccgcagct cctgagcaaa ataatgaaca aactgtctat
     5521 gtcacaccga ccggttcaaa ataccataca cataaatgtg gaaatggtac gtatacccct
     5581 gccactttaa gcgaagctca agctcgtggt ttaacccctt gctccaaatg ttatggaaac
     5641 taattcaaaa gttatactat aataataaaa ttcttctgaa acataaaaaa atagaagatg
     5701 gcgttccaga tagtaaacca aaaataacag tttacacgtc catttcgtca gcttctctct
     5761 tttttcattt agtctgttcc ctctgctttt ttggacatct tcattcattc tttctcaatc
     5821 aaatagtaca cctctttttc ttttcgcagt ttatatcttc cttttttcaa tttcattgaa
     5881 aactgtttcg aatgtttatg ttttacatgg attttaagca ggagctcctc atgttgcaag
     5941 cgatagttcc tgccttttaa atcagaaaat ctcactagtc cgtattcatc agaagctttc
     6001 acaaatggaa ctttttctct agtaatatag tgtttgccgt tgagcgtttt tacagaaaag
     6061 accattcctt cgattggtcg tccgtttgtg ttctttacat aaaaagataa aggatagttt
     6121 cgcttagcga tggccaaaga atctaaataa gcgatgagta gccaaactaa gccgattgat
     6181 ccaagtagta taccgataaa ccaaataaaa aatttccatt ttttccattg atcaattcct
     6241 tggatcgctt tttttgcctc ttttgcttga taaggaatac gatgccccgt cacaagcagt
     6301 cgatgtgtat tgaccatata aggagtacag gtaagcaaag tcacgagatc tctgcctttt
     6361 tggataccca aagaatctac ttcatcaggt aagaccactt ggattttttc tacttgatac
     6421 gccaatgtct ttccattgat ctggatgaaa aactggtctc cttttttcaa cttaggcaaa
     6481 tctgtaaata attttgcttc tgggagtcca cgatgcccag aaagaacggc atgggtgttt
     6541 ttcccgccag tcggataaga actttcttcc aataatgacg ttcctttttg caaaaatatt
     6601 tccgttgtct gatcgaatat aggtaagctg acattgattt ttgggatttc gatgactcca
     6661 agcatatgtt ccataaaaaa ggcattacta ggtaaatctt ttaatgcttt tgcatcaact
     6721 gcttggttga aactgcctat ccctggtgat acgttttgct ctgccaactg ttggtttttc
     6781 tttgtcattt tttcctgctg tttttttatt tcctctgaat tcttattcga tgcttgcttt
     6841 tgataatgga tgatcatttg ctgggcaaga aaatcattca gtgaatcttc tacaaaagga
     6901 taagaaaaga tcccgatccc aacgactaaa atgattgcca tgaagatgtc cagtattctt
     6961 attctgcttt tattcatcat gtccacctat tttctaatat gtatatgaag aggttgtgaa
     7021 atcagcgcct tgacctgagt attagcgaag caaacggcaa aatagttcct cctattttgc
     7081 cgtttgttga gcgaatacca agagaccgac cacttgtcac aacctttctc cccatttgaa
     7141 tcactatcgt ttatttatcg tatgattttt gtttccaata gtttaagctt ctgtttcttg
     7201 atggcgtttt ttgaaataga tcactgctcc tccaactaaa gcagtaccta ccaagatgaa
     7261 tacgatgatc cccataccac cagttgaagg caagattcct ttaggttggt tatcgatcgt
     7321 tgtttcatca gaagttgttg gatcatcatc tactgtaaat tcagtgtacg cagcttcatt
     7381 cttaggtaat gcgtagcctt ctggtgcttt tgtttcttga aggcagtatg ccccttgttt
     7441 cagcccttcg attgaaaatt tcccttctga atcagaaatc aatttcactt cttcccagtc
     7501 agaacctgtg acttcatctg accaagcata tgggtattct cctgaggcaa ggtttgctat
     7561 ttttttcatt aatttaacag ttggatcttt tgctcttaga atagaaaatt ctgcatcggc
     7621 taatttttct tgcgtgttca catcttgttt gatgaagtgg aaatcaccgt agttttggac
     7681 attttctaca gtaatcatgt tatccgtagt tgtattttcc cgattgacta caccgtttgg
     7741 attcccaaga ttggcttcat ctgcgccatg gatgataccg gttgtttgtt gcaattttcc
     7801 gttttttact ataaaagtag tttctttttg tggattggtt aattgataac catctggtgc
     7861 ttttgtttca actaaagtat aattgccgtc tattaatcca ttgacactga tggatccttc
     7921 agtatcagtt gtgaatgtca acgctgactc agcaggatca tagagagcga caccagtgtt
     7981 ttcatcaaaa ccggtcacga attgattctc tgaatttttg atctggaatt gcgcccctgc
     8041 taacttatct acccctgaaa agttcccagc tttctggatt ttgatattgc tttctttgat
     8101 gacattttta gcatataggt gaatcgtgtc taaaggtttg tcagggtcta gggtaagctt
     8161 aacacgatat ttggcgacgt ttcgacaccg ggctttggtg tttctacaaa gacgtataca
     8221 gcatctttcc catcagattt acctggaaga gtcaggttag ctaatccttc accagaagtc
     8281 gttacacttg cgaagggtgt agcgtctgct ggaactgctg tgtctttact tggatagtac
     8341 gtagcagtga tgtcatatac gttgaattca acgccgttca acggttcgct attcggaaat
     8401 gtcaattccg ttccgttgtt tatttgattt tctggtgctg aagtgaattt caatttatgc
     8461 aaattaaccg taacattttc tggtgtaggt gatacggctg cagaaacctc tgcagttcct
     8521 aggccgagaa cgaaaggaag cagcatgata gcagttccta aaaacgtcca tatttttgtt
     8581 ttgatgtttt tcattttatt tccctcctat tgtttccttt ttgttgtttt ttataaaacc
     8641 aagctgtccc tgttgaaagg actagcaata accctaaaat tgagaaacct ccaagcatct
     8701 cttcgcttgt ttttggaaag cttcctccat ttttttcatt tgatggacca tttgtctgca
     8761 tctgaactgg cgtttttcca ttattcgtcg gatttgcttt tggttcgttg atgatttcca
     8821 atggtatagg atgaagcgga tcataactgc ctttttcaac ttcaaagaga atggttgatt
     8881 gactcaatat atatccttta ggcggtttaa tctccactag ttcgtaactt ccaaaagaca
     8941 atccatggac agaaaatgtt ccatctttac tggaagtaaa aatcgttgct cttgaatcat
     9001 ctttggctac ccaatgattt atcccgtttt cttgcgctaa gtattggtca ttttttttga
     9061 ctagaaattg agcatctgct agtttttgtt tcgtttgccg atccactttg acaaattgtt
     9121 tgcctcctgt ttggatggca agatgtgttt ctactgtttg attgtcagtc gtcaaacgta
     9181 catcgttatc aaatgtcgtt ttttcactgt tttctttcaa tgtcatttgg taacggatcg
     9241 ttaatttttt tccagcaaac gaactaagat cttttccaga atctgataag acaaaaccat
     9301 gttttatttt ttgtgtgtga aatgtatgaa tcttgtctcc accaatcaaa aaatcgatcg
     9361 tttctggttc tagccataac tgaggatcag ctgtatcttt gatcgtatag gttcctatct
     9421 cgttgatgtt ctcaggaatt gttacggtga tgagataagg gactttatcc ccatctgcaa
     9481 aatctgtctg cttattctct actgtttttg ttaatgtgag tgcagcaggt attttttgtt
     9541 cgctctttgg atacaagtgg atggtcgtca atttatgatt agatgaatct gtcacaggaa
     9601 gcacaacgac aaatggtgct gatttttctt ttacttaatc tgaagtcttt atttccgtaa
     9661 atcggtaaac agcgtcacga ccttgctcat ctttgtccga tgcactaaaa gaagcaatgc
     9721 cctcttcctc gtctactgtt tttgtcacat tttctgccag tattttttca ctatcacttt
     9781 tttgtgctag ttttctttgt gcgtcttcca cactacttcc ttctgaccgc agcttgtaaa
     9841 attcatccga gacatcatat atagcgaaag taacgccgtt caaccctttt actccttgaa
     9901 agttatccgg gatatttatt ccgtcgtttt gactgatact tggcatctta tcgctttcga
     9961 acattcgatt atgcaaagta aatgtaatag gtgattctct agctgacaca gtcggagaac
    10021 ctataaaaaa gaccagtagg ataaaaaaga gaacagcaaa tatatccaca cgtacatttt
    10081 ttgttttttt catcgctgtt cacctgcttt tttcttacga tggataaaat aaaagaagcc
    10141 agaaaaaata aagatcagtc ctaaaaagac aaagggcagt agacctatcc cacctgtcga
    10201 aggaagcaag agagtcggat tgatcgtcaa cttagcggta tctgttgcga taatcgtata
    10261 attattgttt acacttcctt cgcctaaact aatcgttact atttgtgatc caatatctgt
    10321 ccggctgtta actgttaggg tataatccaa tgattcgcct aagacaacac cggtaacgtg
    10381 gagatttcca accgaaatcg agtgactttg ggcatcataa ttaaaggcag cgtcatcgac
    10441 agtaatcact gcgttagctt tatagatggt ataagttcct gatgtgttgg ctatatcagt
    10501 aaatgacaac ttgggatttg ctgctttgac tttgtctatt ccgctattcg ttagtttaat
    10561 tgtatagctg ccagcattaa ccatattttt tgctgattgt gcatctgctg tgtaatccat
    10621 actgctaagt gccacttgta ctggagtaag cgaactagtg acaccctctg ctagcttgac
    10681 atggattgac gggacacctg cttttccatc atatgtctta ctgccactga gctctaccgc
    10741 accgctgatt tgcttaatcg tatagacatc agatgtctgc acgatagtaa ataaatagtt
    10801 tgttctggca gctagtttag ctagtccgct ttttgtcaat tgccaagacg tataggttcc
    10861 aatttcagta ggcgcagtta cttcaactcc cttttcattc atcgctttga aatcagttgg
    10921 attccatgtg atttgatcaa tactgagatc attgtttaaa agggatgttg attctgtttt
    10981 atcattaaag gcatatttaa cgatcggtac aacagaaaga ccatcatagt acttactgcc
    11041 atttgcattg attgatactg ttgcatttgt cttataatat aggatgactt cagaaatctg
    11101 ttttccattt gcgtccttta cgattacatt tccatttgta tctaaactag ctaaaacact
    11161 cattgctgat tggttctttg tttctatcgc tgaaacagct gtaaaggtat atccgttgat
    11221 agtaggcgta ttagtcgtca ggtcttgtgc agcacttccg taagtaagat tcattatttt
    11281 agaaggagca atcatctgtc caaaatagtc ttgatactta atagtgattg gtgtttgttt
    11341 gcctgtatag gtcaccgtat cgacgttact ttctagggct gtgaaagaac cgtttgtttg
    11401 tgcaaaagaa tagcccgtta ctgctgttgg agtgataacc actttgtcac ccacatggat
    11461 tccagataat gtagtcccgt acgttccgat ttttgctgct ccaccattga ctgtataaga
    11521 aaaagttcct gtccgattcg cattgacctg aaccgttgct gcttgatagg ttggaaaatt
    11581 tgaaacattt cccttaccat caacgatctg cccatttttg atcgagtacc ccgtgaatgg
    11641 aatatcattt gctaactgta taccgattga aaaagtactc atacctcctc cggcaggaag
    11701 ccctccccat gttgagggtg taaaagaata acttttatcc gcattgggtg taactgaatc
    11761 gatcgtattt ccagcggtag ccacccccat atagatactt tttgggaatg tgatagtagt
    11821 accatttact gtggagccaa taaacagatt atggatatct ggacggttat caataaaagc
    11881 gattgctttg gttacgcctt gtaacgcagt tttatccgca ctcatcgatc cgttaaccgc
    11941 aacaatgact ccatctttgg catatatcac tgtatatcca tctggtatgg tatgtccgtt
    12001 gaaattcgca gtggccgcaa cagtactaaa tgtctggctt ctacctgttt ctgaataagc
    12061 tttctcccct gctgcttttg ctgctgtgat ttctttttct gtcggatcaa tcagttgagt
    12121 cgaggatgtg gttgaggttg tctcgttgtt gctagactga ttggtgcttt ctatggactg
    12181 tatttcagaa tagggtggac tatttgtctc ctctgtcgtt tggttagcaa aatttgacgt
    12241 ttctgtataa acgtttacat aaatacttga taagctccct aagaaagtaa aaatcaagat
    12301 gatcgaaatc ataatgggat gtaagtattt tcttttagat acagctttga gtctagaaac
    12361 aaaatgtttt tgacatatac gttggatttt attttgagtt ttcttaatca ttttcatccc
    12421 tcctctcaat aaaaaatcat caaataatcc tttacacgtt attctaaatt taatttttat
    12481 tattttattg atgtatagaa agtttggggc tttttttctc ttttta
//
LOCUS       DARPZF010000068        12064 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.071, whole genome shotgun sequence.
ACCESSION   DARPZF010000068 DARPZF010000000
VERSION     DARPZF010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.071"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..174)
                     /locus_tag="SLE65_002442"
     CDS             complement(<1..174)
                     /locus_tag="SLE65_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HEI8449700.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIACVIW"
     gene            complement(285..455)
                     /locus_tag="SLE65_002443"
                     /pseudo
     CDS             complement(285..455)
                     /locus_tag="SLE65_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(629..2704)
                     /locus_tag="SLE65_002444"
     CDS             complement(629..2704)
                     /locus_tag="SLE65_002444"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEI8449701.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDIKTDRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKDHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEV
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2706..3623)
                     /gene="glyQ"
                     /locus_tag="SLE65_002445"
     CDS             complement(2706..3623)
                     /gene="glyQ"
                     /locus_tag="SLE65_002445"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEI8449702.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRF
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARSVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(4007..4819)
                     /gene="recO"
                     /locus_tag="SLE65_002446"
     CDS             complement(4007..4819)
                     /gene="recO"
                     /locus_tag="SLE65_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEI8449703.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFLSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHAYPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKMPEKNMPEKEIPEKEE"
     gene            complement(4962..5861)
                     /gene="era"
                     /locus_tag="SLE65_002447"
     CDS             complement(4962..5861)
                     /gene="era"
                     /locus_tag="SLE65_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEI8449704.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYTALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5876..6271)
                     /locus_tag="SLE65_002448"
     CDS             complement(5876..6271)
                     /locus_tag="SLE65_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HEI8449705.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQIDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(6255..6731)
                     /gene="ybeY"
                     /locus_tag="SLE65_002449"
     CDS             complement(6255..6731)
                     /gene="ybeY"
                     /locus_tag="SLE65_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEI8449706.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6748..8940)
                     /locus_tag="SLE65_002450"
     CDS             complement(6748..8940)
                     /locus_tag="SLE65_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HEI8449707.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNTGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(8964..9935)
                     /locus_tag="SLE65_002451"
     CDS             complement(8964..9935)
                     /locus_tag="SLE65_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEI8449708.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10640..12019
                     /gene="brnQ"
                     /locus_tag="SLE65_002452"
     CDS             10640..12019
                     /gene="brnQ"
                     /locus_tag="SLE65_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEI8449709.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
BASE COUNT         3266 a         2503 c         2202 g         4093 t
ORIGIN      
        1 ccatataaca caagcaataa tcactgtatc gcgttgcttc agttgatcag tatttcttcg
       61 gtttttaatc ttatctggta cacaattgtg gtatatgtta gaaacagttc tcataatttc
      121 cttgaatgtt ataaaagtat ctgtataatg ttcagtatat tttgatgaac gcatatgtag
      181 tcctcatttc ttgggagttt tgagactact atatgcgttt ttttgttgat ttaccaacat
      241 gtttagacat tttcctctaa gaaaaaatta actagcacca cgggttgttg ataatattct
      301 aaggctgatt ttccttgctt gaagaacaga tatactttat ggatcgtttg tcttgaacga
      361 ttcaagcaat gggcagtttt agcaacagat tgattcattt tgaaataaga ctctattatt
      421 acaagttcat ccgttgtaag atgggtatag gtcatttgta ctcactcctt ataattcttt
      481 ggtcggaact attttgagtg tagcacaaat gactttttta gttgtctagc ttaattttac
      541 aatcggcgag ttatttatat ttataacaaa taaaccagag aaatagccta ttttgtgcct
      601 gttctctggt ttatttacat attagaaatt attttgtgat gatttgatct aaacttgcta
      661 gtgacaaagc catggcagca atttgactta attgcgttaa tcggttctta cgtactgctg
      721 gttcttctgc catgaccatc gtctgatcaa aataattttc gatcagtggg cgaaggctta
      781 caagctgatc ataattttcg ttgatcgttt ggtcagcaaa gcttgttttc attacctcta
      841 ctgctttgtg cagttctttc tccgcttcgt tttcgaacag ttcagggtct acttctgatt
      901 gtttttcaag ctccgctttt ttcgctaagt tcacgacacg tgtcaaagct tccatcgatg
      961 gtttgaagtc ttcatctgca agatgctgct tgaacaattg tgctgctgca aatacttttg
     1021 tcagatcttt ttgttctgcg ttcaaaacag cttcgatgac atcatgacgg atattcttcg
     1081 ttgtcaataa ttggcgcaga cggcctttga taaagtcgat cacctgttgt tgtcccgctg
     1141 acaagccaat gccaaaacga tccgtatctt tactgataac ttcactaatc gtttcttgca
     1201 gaacagacaa aggaaaggcc cattttttcg attcgatgat tcgaacgaca ccatatgctt
     1261 gacggcgcaa agcatatgga tcgtttgagc cacttgggat catcccaact gcaaagaaag
     1321 aaaagatact atctaattta tcagcaatcg ctaaaacaga acctactgta gtctcaggta
     1381 aatctccttc actggatata ggcatgtaat gttcacggat cgctgttgct acggctggtt
     1441 tctcgccttt aagcagagca tatttttctc ccatgatccc ttgtagttca gggaattctc
     1501 ctaccatgtt ggttactaga tcaaatttat agatttcagc agcgcgttgc agatccatca
     1561 attcttcctc agacagtcct acttgttcgc ctatgatgcg agcgatgact tgtacccgtt
     1621 gcattttctc atagatgcta ccgatttttt catggaaagt aacagttttt aatttttcaa
     1681 cgtattggtc gattgaagct ttcttgtctt cattataaaa gaattccgca tcttctaaac
     1741 gagcagtcaa tactttttga ttgcctcgta ccacattttc caattttacc cgatcgccat
     1801 tacgagcaga aataaaatga ggaagcaaca taccttgatc gttccgtact tcgaaataac
     1861 gttgatgttc tttcatagaa gtgactagta cttcttcagg aacagataga tatttttctt
     1921 cgaagtcgcc agaaaagaca gttggatatt cgactagatt gttgacttct tctagtaaat
     1981 cttcatctag atcaatgatc cagtgatctt tttctgctaa ttcgtttgct tgtgtgatga
     2041 tcatttcttt tcttttttgc ggtgaagcaa taacaaattg ttcatttaat ttttcttcgt
     2101 attcttttgc atgcgcaaat gtcacatctt cgcctaagaa acgatgacct cttgaagctc
     2161 tgtctgtttt gatatccaag atctcaaacg ggattacttc gtcatctaac aatgccacga
     2221 tccagtgaat aggacggata tattcaaaat cgtattctgc ccaatgcatc gttactggga
     2281 aagtgaggct tttaatgaca tctgctaaac ctgtcaatac ttcttttgct tctttgccgt
     2341 gagtgtattt cgttacatag acatattcca cgccttttaa ttctctaaaa gtgatagcat
     2401 ctgtcgtcag accttgtccg cggacaaatc cttccgctgc tttcgtccag tttccatctg
     2461 cgtccaaagc aatttttttg gctggtcctt tgacttcttc ttcactgtct gcttgacgtt
     2521 ctggaatgtt tgttactttg attgctaaac ggcgcggtgt agaaaatgtt tcaatcgtat
     2581 cataagtcaa ttggttttca tctaaaaatt ttgctgtttt ttcttctaat tgtttcatgc
     2641 ttggtgtgac aacatgagca ggcatttctt ccagcccaat ttcaagtaat aagtcttttg
     2701 ccatcttatt cagcctcctt cacgttttct ggatttgctg tgtttttatt caataaaggg
     2761 aatcctaatt tttcgcgttc tgccacaaag attttggcta cagaacgagc catgttgcgg
     2821 atacgggaaa gataacctgc acgctccgtt acggatactg caccgcgggc atctaataaa
     2881 ttgaatgtat ggctgcattt caaaatataa tcatacgctg gatgaacaag attttcatcg
     2941 atacagcgtt tagcttcttt ttcaaaacga tcaaagttgc ttagtagcaa gtcttggtcg
     3001 cttacttcaa aagaatattt ggaatgttca tattctggtt gtttgaagat ctcgccatat
     3061 ttcacgccat cagcccattc taagtcatag acactttcaa cttcttgaat atatgaagca
     3121 agacgttcta gtccataagt aatctcagaa gtaactggtt tacaaggtag tcctccgact
     3181 tgctggaagt acgtgaattg tgtaatctcc ataccatcaa gccatacttc ccaacccaca
     3241 ccggcacaac ccatcgatgg gttctcccag ttgtcttcaa caaaacgaat atcgtgttct
     3301 aatggatcaa ttcctaaaaa acgcaagctt tctaaataaa gctcttggat attttcaggt
     3361 gaaggtttca ttacgacttg aaattgatga tgctgataca aacggtttgg gttttctcca
     3421 taacgcccgt cagctggtcg gcgggatggc tctacataag cagcattcca tggttccggt
     3481 ccgattgccc gtaagaatgt atatgggctc atcgtacctg ctcctttttc tgtatcataa
     3541 gcttgcatca gcatgcagcc gtttgatgac caaaattttt gtaatgttaa aatcatatct
     3601 tggacggtca attttttact catctgtttt gcccctttca atttttaagc gttgctgtca
     3661 ataagaatac aggaaagaaa acgacaaaaa gtccctatgt ctgattacag acatagggac
     3721 gaataatttc gcggttccac cctacttccg aataaagatt cggcagcttc atttatcgta
     3781 ctcgcaagtg cctcttcaaa aatcgtttgg gtccggcttc cactctcccg aactcgctaa
     3841 accacgtgtt ttttactgat cttggtcaat gtacgtattc attttgcagt tttcttgttt
     3901 atataataga tcctctcagt gaacgatcta tttaatctac ggttaataat agacggaagt
     3961 ccctgtattt gtcaaatagt tttgattttt ttgttgtatc tttcatttat tcttcttttt
     4021 caggtatctc tttttcaggc atatttttct ctggcatctt taatacgtgt gcccaagact
     4081 tcatttgatc aatgaacttt ttgcttttta gatgaatacc gacatattca tcatacaact
     4141 ggtcaatgag gtcacggatt gcctgcttcg tttcttcttt caagtggatt ccactgatct
     4201 tatcataaga aatagccgaa aacattcgaa cgaaataaac agcgcgagga tatgcatgat
     4261 aacggtgttc gtccattggc cagtgtttct cgcatatcac gccgccatat ttggaagaat
     4321 agtcaaattt tccttttgtt tccccgcata cgacacagtg cgtccaaatt ggcgcgattc
     4381 cgaagcgttg cagtatttga acttcaaaga tattcgtgat gatttctgca tcatctcctt
     4441 ggtccatccg ctgcagagct tgttgcgtaa attggaataa gtgcgggtca tattgatgat
     4501 cttcgattgc tgcatctact agatttagca aatacgtacc ataaccgctc aaaaagatat
     4561 cttcttggat gttccgaaac gcatggacgt ctttgacact gcttaaaaac gacaaacctt
     4621 cacttagaaa attaccgata tagactgctt cggtaaaggg gagcaaagcc ggagctaatg
     4681 gctgattttg ccgatggatt cctttgatat aaaacatcat tttgccagaa gattccgtaa
     4741 agattttgac taatttatct ttttctttgt aattacggct agataaaatc aagcctttcg
     4801 attctgcaag ctggctcata ttctccctcc taaaaaataa atctggaaaa gcagattctg
     4861 ccgatccaga ttatttatgt tacgatcttt cgctgttttt ctcaacgtac ggatttttat
     4921 ccagtttatt tctataccta acctataaga agtccagaat atcagtactc gtcttttcgg
     4981 tagccgaagt cttgcagata gacttttttg tctcgccagt ctttttggac tttgacccaa
     5041 agttctagaa atactttgtc tcctaaaaga ttttcgatat cctttcttgc tttcgttcct
     5101 acttgcttca gcatttttcc acctttgccg ataatgattc ctttttggct atctctttca
     5161 acgatgatcg tggcctggat atggatttta tcattctcgt ttcgcttcat cgaatcaaca
     5221 acgactgcga cagaatgagg cacttcgtct cgtgttaaaa acaagacttt ctcacggatc
     5281 aattcagaaa cgatgaagta ttcaggatga tcagtcactt gatcatctgg aaaatattgt
     5341 gggccctctg gcatttcact gactaataca tccattaagc gttcgacatt gtttccttct
     5401 gtagcagaga tcggaatcac ttgtgcaaaa ggcatctgcg tcgaataatc ttcgatgatt
     5461 cccagcaact cgtctggatg gatcttatcg attttattga taatcagata aactggagaa
     5521 tgcacgtttt ttagacgttc aataataaaa tcgtctcccc ggccgcgttt ttgatcagca
     5581 ctgatcataa ataagactgc atccacttct ttcaacgcag tgtaagctgc ttctaccata
     5641 aaatctccta gacgatgctt tggtttatgg attcctggtg tatcgataaa aatcagctga
     5701 gcttctggtg tagtatatac tccttggatt ttatttctag ttgtctgtgc cttgtcactc
     5761 ataatggcaa ttttttgacc cacgattcgg ttcaataatg tggattttcc tacattcggg
     5821 cggccgacga ttgcgacaaa ccctgattta tgttctggca tatacgttct cctttttaat
     5881 taaacaacaa atgatatatt ttagggacaa ataaaatcaa cccaatgatg acagcaaaac
     5941 aagcggtcac taaaactgct ccagctgcca tatctttgat ttttttccca atcggatgaa
     6001 aatgaaaatc cgtaaacatg tccactacat tttcaaaaac agtattgatg atctctacta
     6061 tccaaacgag aaaaacagct aaaagcagcc ataaccactc tatccgatca atctggaaaa
     6121 tcacgcccat aaataaagca aggataccga acgcaacatg tttcctcata ttgcgttctt
     6181 cctcaaaaac ggttttgact ccttggacag caaattccac ggacatcagg aaatgtttgt
     6241 ttttctctac gtttttatct tttgagtcca taggcatcca agatctcttt ctgtaaacca
     6301 aacatttctt tctcatcttc tggtgtcata tggtcatacc cgttgatatg caagaatcca
     6361 tgtaccgcta aaaagccaag ttcccgatca tatgaatggc cgtaagcttc tgcttgttca
     6421 gcagcacgtt caatagagat catgatgtct cctagtacac gaggcaatgg attctctcca
     6481 tcttcaaaaa tcactgggat ttcgtcttcg ccttcttctt ccagagcaaa actgatgacg
     6541 tctgtcggtg catcttttcc acggtaatca cgattgatta cttggattgc cgcattgtcc
     6601 atgaaagtaa cagacatttc tgtttcctct ggcagcttta aataagatgc tgcaaattgc
     6661 agcaagtcat cgatttcttt cattttctct tctgagactt ggtttgtttc atccataaag
     6721 gtaatatcca ttatacatcg cttctttcta ttcttcttgt tcttccttta tcttctcaac
     6781 ttctgttttc attttaggat atttgatccg agaatggaag gtgctactta aaccgctgat
     6841 caatgatttt tccacttttc ggatttcttt caaggtcaat ccactatcgt ctaattgacc
     6901 atcggaaata cgctcttcga taagattatg gacaaaactt tcgatttttt cgctcgttgg
     6961 atgatccatt gcccgtactg cagcctcaca actgtcagca atattgacga tccctgcttc
     7021 acgactttgc ggttttggtc caggataacg gaattgctct tctgttactt ccggattgcg
     7081 ttctttcgct ttgatgtaga aataacgcat tagcgtggtt ccatgatgct gtttgcaaat
     7141 atcgatcacc atttgcggca tattataatc ttccaatatt ttggctccat ctgtcacatg
     7201 tccaaagata atatgtttac tgtcttctgg caataagaaa ttgtgcgggt tttccgctcc
     7261 tgaaggcaag ttctcaacga aaaagctagc gtgtttgatc ttgccgatat catgataata
     7321 gcaagctact cgagttagta aagaacgtcc gccgatttct gctacagcgt tagcacttag
     7381 attagctacc atcatactat gatgatacgt acctggcgct tcttccagca actgtttcaa
     7441 taaaggatga tttggattgc tgagttcatt taatacaatt acactgtcat cattgaccat
     7501 caattcaata tatgggtgta gaccgatcgt cagcaagaat gagaagagtg caccagtgaa
     7561 cccgcagaca agcattaacc aagtcgttgc atcaccaaag ctcattcctt gatagacgat
     7621 caaaatgaca tccatcatca caggaaaaat aatgacccac atggcagcag ataatccttg
     7681 ttctgagatc cgtttacgtc tgacaatcgt tgccatgagc ccagagaaaa cataagacat
     7741 caagataatc gttagaaagt tcgtgccaat cgaatcataa aaaatgaaaa gtgcggatac
     7801 tgcttggaaa ataccagcca tgatccctgc tcttcgattc aagaaaaagc ttaaaacaag
     7861 tggtgcaaaa gcagcgggat aaaacagcgg gatataagta gcttgttccg tttggaataa
     7921 ttggaaaaat ttcatcagca ctatgctgac tgacatagct gtcacataga aaagaacgta
     7981 ttttgttctt tctcctgtat tttggaattg aagtgaatta taaatcagta cgccgatttg
     8041 aagcaaaaca gctaaaacca tggcaattag cggaaaaatc gaagttgttt gattagtcag
     8101 tcctagtaat tccaattttt tcatagctga agcatcaatt tgattacctt cacgaacaat
     8161 gatttctcct tggaagatca tcactggttg tacagcttct cgtgcggatt gtttcaattc
     8221 ttctgtcttt ttctcattca atacgtcatt cactacgata ccttgatcca ctaagtagcg
     8281 aatcatttgt tgttgtgctg gtgtgacatt caaatattgg atttgctctt ctgcttcttg
     8341 tttaaaagct tccaattcac tttcacgaac ttgtttgctc atctgttcgt caatgagctt
     8401 cagactctca tccctcacag tatgaatctc agtttcagtc atttcaaata tcgtcgaata
     8461 aaaattgttc ggtagttttt gataaaacac aacattttct gcattcacat tttcaaaatt
     8521 tttcttcagc gcggcgatcc gctcttctgt agtaggcttt gggatatttt catcttcctt
     8581 tgccttatca atcttttcgt cataagattt gttgatggca tcattcgtct tatcgatcaa
     8641 ttcaaatagt tgcttgatcc gattgttctg gtcatctgca agatcttttt ggtaagtgta
     8701 ttctggagtg actgcttctg ctgccagttt tcttttttgt tcggtttctt ccgtgttctc
     8761 gatcgttttg ttcgcacgga tactttcttc tgctacttgg ccttctctga aatcattggc
     8821 cttttgtttg acactactaa atgtaacgcc gcagataatg ataaaaaaca agaacagcag
     8881 gaaaggcaat gctgcctttc caagtttttc ttgtagtttc tgcagtgttt tattcaacat
     8941 gtgcttatcc tcctaagcaa agcttattct tgatggagat ctgccttttc ataagctttg
     9001 atgatttcgg caactacagg gtgccgaaca acgtcacttg cttcaaaatt aacaaaatcg
     9061 attttcttga tttgctttaa tgttcgttct gcatgaacaa gaccacttgt tgtccctcga
     9121 ggcagatcaa tctgactcgt atctccattg acaatcattt ttgattgata accaagacgt
     9181 gtcaggaaca ttttcatctg agcaactgtc gtgttctgtg cttcatccaa aataacgaat
     9241 gcatcatcca atgtccgccc ccgcatgtaa gctaaaggag caatttcgat cacgcctcgt
     9301 tccatcaatc ggttcgtatg atctaatcca aaaatttggt ataaagcatc ataaacagga
     9361 cgcagataag gatctacttt ttcttttaga tccccgggaa gaaagcctag attttcccct
     9421 gcttccacag caggccgcgt caaaatgatt ttttgcactt cacctttttt caaggcagcg
     9481 attgctaata ctactgcaag aaaagttttt cctgtcccgg ctggtcctac gccaaatacg
     9541 atatcatgtt tggctaccga ttcgacatat ttcttttggc cgctgttttt tacccgtata
     9601 ggttttccat tacggtcttt gacgatctct tcctcataca tctcaacaaa ataatctaat
     9661 gtgccttttt gccccatttt cagtgccgtc acgacatctg gtgtacttac atggattcct
     9721 cgtttgatca attcctgcaa tgtccgaatg actgaggcag ccaaggaaat ctgggattgt
     9781 tcgccaatga tctgaatgat ttctccacgt gtatggatgg ttgtttctgt tgtttcttca
     9841 atcagtttta tgtgcttgtc gtgtgcacct aaaagcatgc tgacatcatc agcagccgtc
     9901 aatctaatct ctaaagaact agactcttcc gtcaaaaata gacatcccct ttttttcgat
     9961 tcattctttc ctattttacc atactcagaa gaaactatat agcaaataag aaaaggttct
    10021 aaaagagttg cttaaccata agtaccaaga aacgttaaaa aatagctgct tccattctct
    10081 aaaggtctcg tttgaataaa aaaagctgat catgtaagct atgcataaga tagaggacaa
    10141 gtattccgtc taacttagca agtattctct gggtattttt cttgtttcaa aaaaagaaaa
    10201 caaaatattt gaaatattct tgcatttcaa aaaaaacagg tgtattataa cgtcaacaaa
    10261 taaatataca gcaaagcgtc gaggaaaaca gtaggctatt cagtgattta ttcccagtga
    10321 gtcatgtaag tgagaaatga caataaatcg aatagacgaa catcatttcc gagtcaatgt
    10381 cgaaaacgta gatcattgtg gctgcctcca ttatcaggcc agcggataac tttatcgaaa
    10441 agcgtccgtg aatgaagaag cttttttaag cgaaaaaagg tggtaccgtt ctagaatcta
    10501 gagccctttt cccaagtgga aaagggcttt ttttatattt taaggtggtg gttttcatgg
    10561 aatctgatat tagtggtatt tctagtttct gcaacgttta ttttgttact caaaatgata
    10621 attattggag gaaaaattta tggaagaaac aaaaacttat tcatggaagc aattattgat
    10681 ggtcagttca cttatcttcg ggatgttctt cgggtcaggt aatctgatct ttcctgtcca
    10741 cttaggtcaa atggctggat caaactggat cagcgctggt gtaggatttg ccatctcagg
    10801 cgctcttttc ccattattag ctatcttagc tgtagtagtg acaaaaagtg atggtctgta
    10861 tgacttagct aaacctgtcg gaaaatggta tgctgccttg ttcttgatcc ttgttcattt
    10921 aacgatcgga ccattctttg gtacaccgcg gacagcagca actgcttttg aaatggctgc
    10981 taaacccttt ttgcctgaaa aatatgattc attaggtatg tttttattct ctgctctttt
    11041 ctttttactt gcttatttcc ttactgtaca tccaacacgt ttggtcaaat atgtcggaaa
    11101 gtatttaaac tccttgtttc ttgcattatt agctatcatt tttgtcgttt ctttattcca
    11161 acccatgggg aatctaaacc aatctgctgc agattcttat cagacgaacg ctttgacaaa
    11221 tggcgtttta gaaggataca acacggttga tgcagtagct ttacttgctt taagtgtcac
    11281 ttttgtccat gcagttcgtg atcttggttt taaagataaa aaagtcacag aattaacagc
    11341 aaaagctggt agcctgagcg ttgcgttaga agtcatgatt tattttggtc tggtccttct
    11401 cggtgcgatg agtttgaata agatgtcttt atcagaaaat ggcggaactg cactttctca
    11461 gatcactaat ttttatttag gtaacttcgg tgctagcttc ttaggggtaa tggtcacatt
    11521 aggtgtcttc actaccgcta tgggactcgt tgtttctttt gcacaagatt tccataaact
    11581 gttccctaaa gtcagttata tgacatggct gcggttaacg acttttgtct cttttgtcgt
    11641 tgcgaatgcc ggattggata atatcatcca atggtcttta ccagtattga tgcttttgta
    11701 tccattgtca cttgcgttaa tcttgctttc cttaacagca aaattcttcc aaaagagtcc
    11761 atttgtctat caagtaacga tgttcttttc tgccgttcca gccgtattgg atatgttggc
    11821 aaattcgcct gcattagtga gtcagcaaac tgtcgtagca agcttactag gattttatca
    11881 tcattatgtt ccttttgctg cattaggact tggctgggtc gtcccaacgt tgcttggtta
    11941 cgctggcagc ttgctctttt attatgtata tcgcgtatca ggatataaac aagaagcaag
    12001 tgagttacca gaagaataac caaatcaaac acaatttaac ataagagata ttaaacagga
    12061 aaaa
//
LOCUS       DARPZF010000069        11910 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.072, whole genome shotgun sequence.
ACCESSION   DARPZF010000069 DARPZF010000000
VERSION     DARPZF010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11910
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.072"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            103..1521
                     /locus_tag="SLE65_002453"
     CDS             103..1521
                     /locus_tag="SLE65_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HEI8449710.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            1592..3061
                     /locus_tag="SLE65_002454"
     CDS             1592..3061
                     /locus_tag="SLE65_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEI8449711.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            3071..3538
                     /locus_tag="SLE65_002455"
     CDS             3071..3538
                     /locus_tag="SLE65_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEI8449712.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            3574..4446
                     /locus_tag="SLE65_002456"
     CDS             3574..4446
                     /locus_tag="SLE65_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEI8449713.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            4527..7062
                     /locus_tag="SLE65_002457"
                     /pseudo
     CDS             4527..7062
                     /locus_tag="SLE65_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
     gene            7218..7991
                     /locus_tag="SLE65_002458"
     CDS             7218..7991
                     /locus_tag="SLE65_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8449714.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            7984..8775
                     /locus_tag="SLE65_002459"
     CDS             7984..8775
                     /locus_tag="SLE65_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEI8449715.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            8785..9276
                     /locus_tag="SLE65_002460"
     CDS             8785..9276
                     /locus_tag="SLE65_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8449716.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            9294..9704
                     /locus_tag="SLE65_002461"
     CDS             9294..9704
                     /locus_tag="SLE65_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEI8449717.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            9708..11108
                     /locus_tag="SLE65_002462"
     CDS             9708..11108
                     /locus_tag="SLE65_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HEI8449718.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            11131..11505
                     /locus_tag="SLE65_002463"
     CDS             11131..11505
                     /locus_tag="SLE65_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEI8449719.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         4098 a         1604 c         2391 g         3817 t
ORIGIN      
        1 ccttcgtcga tttaaaaata tttttatgaa acgggttgac atatgaaacg ggttgacata
       61 tattagttgt gaagataaaa accttttcac tggaggaaga aaatggagaa attattaatt
      121 aaaagcaata atcatcaact ttactaccaa cctaaggatg tttgggtcgg agatgttatg
      181 ccttacggga aagaaggaaa attctttatt tatcatcaac gtgatactag aaatccagtt
      241 ccttttggag aaccgtttgg ctgggcttta gcaactacga aagattttgt tcattttgaa
      301 gactttgggg aatctctttt aagaggggat gacaatgaga gagaccagtt tatctacgct
      361 ggttctgtat ttgaggcaaa tggaaaggtt cacgcatttt atacagggta taatcgtgaa
      421 ttcttagcgc agggaaagac atctcaagtg ttgcttcatg ctgagagtga tgattttgtt
      481 cattgggaaa aatcagaaac agcattggag ttagaaccac aagaagggta tgatattcga
      541 aactggagag atccatttgt cgtttgggat gatgaaaaag aagaatattt gctaatttta
      601 ggggcgcgaa agggtcagga taaacatcta caaaccggac gtttagtgga atttacatca
      661 aaagatttaa ctaattggga attcaaaggt gatttttggg ctccgggatt gtataccatg
      721 tttgaaatgc cagaactttt caagattggt gactggtggt atcttgtcta ttcagaatac
      781 tcagatggaa ataaaatact ctatcgaatg agtcaaagtt tggaaggtcc ttggattaag
      841 cctaaagatg aagcttttga tggacgggct tattatgcag gtagaacagc ttatgatgga
      901 aaacgtcgag tcctatttgg atgggtacca acaaaagatc aagaaaatga taaaaacaat
      961 tatttatggg gaggtacttt ggttcctcat gaagtctatc aaaaagagga tttttcactt
     1021 ggggtaaaac ccatagacga agtgtggaat gcattcataa atttacatga tattgccgat
     1081 gtagagatag aaacagcaga cacaagagaa gaagtaacgc ttgtcaaaaa tagtggaact
     1141 ttgtttaatt tagaaacaac aatttcattt gatgagaatc ttagtgactt ttcactgaga
     1201 ttatataaaa accttgagac agatgaatct tacgaatatc gcttcaattt agatgagggg
     1261 cgtcttacat ttgataaaaa cccttgttac ccttggtttc aatatatgga taaaggactt
     1321 attagaccta tatctttaaa gcctaaccaa tcttataaac taaaagtgat tgttgatgac
     1381 aatataatga cactttatat tgatggaatc gctcttaacg ctcgtgtaca tggttgtttt
     1441 ggtcaagcaa ttactattac agcaacaaat ggatcaatga ctgcaataaa taccaagttt
     1501 tcaaatgaaa taaagaaata ataaacgtca atcatgtggc aggtctgaaa atcaaacatg
     1561 acctgtcaca tttaaaaggg aggataaatg aatggactac aaaaaaattg ccgaagatgt
     1621 attggaaaac gttggaggaa aagagaatat ctcaagcgct acacactgca ttactcgttt
     1681 acgtttaatt cttaaagaca aaagcaaagc gaatatggaa atgcttgagg aaatagaagg
     1741 tgcaaaaggt gttcttttca atagtggaca gttacaagta attttcggaa caggtataat
     1801 tgaaaaggtt tacaaagagt tcgttgaatt gacaggagct aaggaagtat ccgtttctga
     1861 aatgaaagac gaaggagtca ataattcagg aaatagactt caacgagctt ttaaagtttt
     1921 ctcggatatc tttattccga tcattccagc ttttattggg gcagcaatgg ttttaggaat
     1981 tcgttcgttg attaccactc ctggaatgtt tggaatggat ggctcattcg ctgatcacaa
     2041 tgtattccta aatgatttat ccaaatttct gggtattatt gcaaccacat ttgattattt
     2101 accagtttta gttatgtatt ctgcaacaaa acgttttggc ggaaacccta ttttaggatt
     2161 acttgtagga tttgttatga ttcatccagg actagccaat cggaatgatt tcgtcatggg
     2221 aactataaag cctgattatt ggcatttatt tggattaagc attccagcag ttgcgtttca
     2281 agggggtgtt tttccagcaa ttttgacttc ttggttttta gcaaaagttg agaaaattac
     2341 aaataaatat tctcctcaag tacttgctta cattttagtc ccaactgtga caattgttct
     2401 tgccaacttt gcactatttt tagtgtttgg tccattgggg aattttatcg gtaatgtttt
     2461 aggtggaatc attgatttcc tatatatgaa gatgggtgcc tttggtgctt ttgtttttgc
     2521 aggcgcgtta caaccattag ttgtaacagg aacacaacat gctattcaag gtattgaggc
     2581 aaacttagtc gcaacaactg gattcaatta tatccaacct atttggtcag tttcaattat
     2641 tgcccaaggt ggcggttgta ttggtatgta tttactcttt aagaaaaaat ctaaagatag
     2701 agatattgcg atttcaagct ttattccaac actggtaggt attactgaac cggctatctt
     2761 tgctgttaat ttgaaatatt caatcgttcc ttttgtttgc tcgtttattg gtgctggttt
     2821 tggtggagca tttatgaaaa tttttgatgt aaaagccatt ggacaaggat tgactgtatt
     2881 gccaggtctg actattgcta atccagttct tccttatata tttggtaatc tcatagcatt
     2941 cattttacca atcattttta ttctcgctta tgataaatat aaagtgttta tccctgaagc
     3001 taaacaccgt aaatttgcag aaaaaactga ctcaaaaaaa ttgccagttc aagtaaagtg
     3061 agatgagagc atgttaaatt tttttagaaa aaatgaaata agcgttgtag cacctgcaac
     3121 cggtgttttt gaaaaactgg agaaattaag tgatccagtc ttttcaaaag gaatgatggg
     3181 acaaggattt gcaattgatg caaaaaacga aacgattgta tctccaatcg atggttttgt
     3241 ttcaagtatt tttcctacaa aacatgcctt aggaataaaa acaaaatcag gaattgagat
     3301 acttgttcat gtaggaatag atacagttga gctaaatggt gagggatttg atattaaagt
     3361 tcaagaagga caaaaagtta aggctgggga tattcttatg accattaatt ttgtagtttt
     3421 tgaaaagaat cacaagacta aagatgtcat tgttgttttt ccagactacc aagacgaaat
     3481 tttcattccg aaacttgaag aagtaaaaca aggacaagaa ttgtttgttc ttggctaatg
     3541 ataagtaatt aataatagaa tcgaggaaaa tgtatggttt ttggggctat tgaagctggt
     3601 ggaacaaaat ttgtttgtgc cattggagat aaagatttga acatatttga aaaagtcagc
     3661 tttcccacga ctacacccaa agaaacaatg aatttagttt tagatttttt taatcatcat
     3721 aaagatgatt tagaaggtat cggagtggga tcgttcggtc ctattgatat tcattgtgaa
     3781 tctaaaacgt atggcttcat tacatcaacg ccaaaacttg cttggcagga ttttgatttt
     3841 attggaagtt taaaaaagca acttaatatt ccaactgctt ggacgactga tgtaaatgcc
     3901 tcttgctatg gtgaatatgt ttctggaaat ggcagaggcc tttcaagtgt tgtttactat
     3961 accgtaggaa cgggcatagg aggtggcgct atccaaaacg gaaacttcat tgaaggtttt
     4021 agtcatccag aaatgggaca tatgcttgta aaacgacaca ataaagacaa cttttctggg
     4081 acatgtccat tccacggaga ctgtttagag ggcttagctg ctggtccggc aatcgaaaga
     4141 agatcaggga aaaagggaca agaagtgact gaaaatgacg ttacttggga aatagaagct
     4201 tattacattg ctcagtgtgc atataataca acattgatgt tatcacctga tgtcattata
     4261 tttggtggcg gagtaatgaa acaaaaacac ttaaaaaaga aagtacaaga taagtttatt
     4321 gagttgatca acggatatgt cgctattccc gatgttgaca attatattat gacaccaaaa
     4381 ttgttagata attctggtat tgtaggttgt ttagctttag caagagacgt taaagaaaaa
     4441 tcttaatttg gaaaaaagat cgtctcgact atttgtttgg ttgatgcgat ctttttttca
     4501 attagtaatt gaagggacgc ctaaaagtga aaaaaaaaat gaaagatgaa gtattagagt
     4561 atatcaaaaa taatttaaag tattacgatt tttctgctca agatattgca atgaaatttt
     4621 gtattaaaag aaatgtcgct tcccactatt tgaatcagtt attttcagat ggaaaattac
     4681 taaagaatga ttctgttaga ccagtaatgt tcaagtataa tcaacaaaag ccaaaagact
     4741 gcttttctaa gtttattgga gcagacatat ctttgaaatc cactatagat aaatgcaaag
     4801 ctactgtaat gtatccccct aatggcctcc cattaataat aaaaggaaac agtggcgttg
     4861 gaaaaagttt tttagcaagt ttgatctatc agtatgctct tgatagaaaa gtaattcata
     4921 atgacgcaaa atttgttgtt gtgaattgtg cagattatgc aaataatcca gagctattgt
     4981 cagcagtttt atttggatat aaaaaaggag cctttactgg ggctgaaaaa gatactgcag
     5041 ggatgctatc ttctgctaat ggaggatacc tttttttaga tgaggttcac aatctaagtg
     5101 cagaaaacca agagaaattg tttcttctta tggattctca aaagtatcgt aaacttggtg
     5161 aaagtgtgca atgggagtat gcaaatgttc gccttatctt agccacaaca gaagataaaa
     5221 atacctcttt gttagcaact tttagaagac gcatcccagc tgaaatcact ctgccagatt
     5281 acaataatag aagtacatct gaaaaaattc aattattatt tgaatttctt aaagatgaag
     5341 caattacgat tgattcaaaa atattttgtt cgattgaact ttttactgat cttttatcga
     5401 aaacatttga aggaaatgtt ggagaattga ggaatgaaat caagcttctt tgtgcagaag
     5461 gttatttagg aaataagaga aagtcttcaa tttatttagg ggacaaacta gacagcggtt
     5521 tttggataga tccagaaatt agtatagatt taaaaaaaat gtttcttaaa tcactttctg
     5581 aaattgattt gattgaactt tttcaaaatc acatttcaat tgaagaaagc atgagtcaat
     5641 taagagatag aatacttaaa gagtgtgcag gttcttctga gtataattat ttagaaagtg
     5701 acgaatttat agcattaaga aactatgttg ttaataaaat atcaccaatt attgattcga
     5761 caggtctatg tttattagat gaattcttgg cggatatcag tctatttata atgtttattg
     5821 atgtaattga agaaacatca agaaattttt tgctgtctaa gttcagaaaa tttcgtatga
     5881 aaaatgataa acaaaaatta ttggcaaatg agatttggag tagtttagaa gtcgaagaaa
     5941 gtaaacaaga acttttgttg aaatggatac tttttcttgt aaagaagttc tatgtgaaaa
     6001 taccagaaac ccattgtctg atagttatgc acggtaaaat aacagcttct gcggatcgca
     6061 agggaaacaa ataagttgct gaatacatat gtttatgagg ctttcgatat gccaattgaa
     6121 ggtgagacta gtgacttaat taacctaatc aacaattttt gtaaaagtat agatacgacg
     6181 aatggactca ttctgctagt tgatatggga tcattggaac aaatgtatga aaaaattgaa
     6241 tccaatgtaa taggtgattt ggtaatttta aacaatgttt ctacagcttt agcgattgaa
     6301 tgtgggattc aagtttgcca aaaaaagcca attagtcatt tttaccagat ggattttgat
     6361 tcgtttcaag ttaaagttca gtattataaa ggattatcac aaaagaaaaa tgtaatagta
     6421 tcttgtctct ctggtgaggg gatttctgaa aaagttaagg atattttaaa acggtatctc
     6481 gataatcaag tggagatttt gatttttgat tttaacgcat taaagaaaat agcaaaggaa
     6541 aaagatacta tgatttttaa gaatacaatt tgtgttcttt caaccactga attttacatt
     6601 caaggaatcg attgtttaaa tttagaaaat ctaattaatg ggaatcaaac cttagaaaaa
     6661 ttaaataagt atatggactc ggatagctgt gagttctgct taaatgaatt agttaaactc
     6721 tttactattg aaggcgctag tactaagctt cgctttttag attccaaaaa agtattcaat
     6781 gagatagaaa aagtactata tttgtatgaa aaatattacg atgtcaaaat cccaagtttt
     6841 ctgagaatta atctatttct acatctttct ggaatgattg aacgaattat gattggtgat
     6901 ggaataacaa atgaacattt gaaagaggga gcgcaactat ttgatacttt tttaaatgta
     6961 tcaaaagatt ttttttcaga aatcaaagat atttactgta ttgaaatacc caaaggagag
     7021 tatgagttaa tctatacaat ttttgagcag actattttct aaatagcata ctagcgtcta
     7081 aaaaaatgaa agggtgtcca aagtatattt agacgctcat ttaattaata tttactgtat
     7141 tttcccgctt tattggataa tgttagttgg cacagtaatt gcttatataa aagtataaga
     7201 agaaaggaga gaacaaaatg gcgttttggc aaacattttt agttgtgttg tatggatttt
     7261 tcattaactg ggataaggaa gggcccaaaa tcggaacctc ccaacctgtc gttgcaggtt
     7321 tcttgaccgg acttattatg ggagatattc aaactggact ttatatcggt gggactttgc
     7381 aattaatgac actaggtatt actagttttg gtggtgcatc agtaccggat tatcaaacag
     7441 cagcattgat cggtacttat ttagcaatct caactaacca ggatgcttct ataggaataa
     7501 ctttagcaat accggtagca atgttaattg tacaactaga tgttctaaag tggtcaacaa
     7561 acattttttt tcaacaaaag gcagaaaaat tcgcacaaaa agaagattat caaaaattag
     7621 agtggatgca atatttggca tcaattaata caagctttgt atctggaatt cctgttttgt
     7681 taactgtgat attaggccca acgttagtgg gaagtgcaat caattatatt cctgaatggg
     7741 ttaccggtgg tttaaaggta gcagggggac tattacctgc tgttgggata ggaatgctac
     7801 ttaaatattt acctacaaaa gattactttg cctatttgtt agttggtttc gttttggcag
     7861 tttatttcca aataccaatt ttagggattt cgttacttgg cgctgcaatc gcactaatcg
     7921 tatataaaaa tagatcaaat aatactcaag tagcaccagc tgcaacagga ggttttgacg
     7981 aagatgaata agaaactgac aaaaatcgac aaacaagtaa ttttccggtg gattctcaat
     8041 ggtgcaactt cattaaatta tgaaaaaatg gaagggttgg gttatgcgta ttctatgctt
     8101 ccttttatca aggacacata taaagatgat cctgaaggaa tgaaacaatc cgttttagct
     8161 cacttacaat tttttaacac tacgccgtat acagcgcctt acattattgg tatgaatgtt
     8221 ggaattgaaa aagaagaaaa aaataagtct ttggaagcag taagtgctct gaaaacaggt
     8281 ctaatgggtc ctttagcggg aattggagat agtgtatttg tagttattcc atggactatt
     8341 tttggagcaa ttgcagctaa tatggcattg gaaggtagtt ttgttggaat tattttgtgg
     8401 atactggcat caattttatt aaggattact gcttatcctt tataccttgc tgggaaagaa
     8461 tcgggtgcga gcctactaac tcaaattgaa acaaaattaa agtctattac tgatgcagta
     8521 tcaattttag ggttaatggt ggtcggtgca ctcattgcca cagttgtaaa agtgaatgtt
     8581 ggctttgaat ttaaacaagg cgacttaaca atgaccggaa atgaaatctt tgatcaagtt
     8641 atgcctggtt tattacctgc atgtgtagta gcaattgtgt attatttgtt aggacgaaag
     8701 gttaaaccag tttatgtaat tctattaatc ttagtagttt ctattgcgtt aagagcgtta
     8761 aatattttga agtaggtgtt gaatatggat gaaaaaatga aaggtattat acatgttcgt
     8821 attgatgatc gaatgattca tggacaagta gcaacacaat ggacaaatca attgagtgct
     8881 aacagaatta tggttattaa taatgaagta gccaatgatg acgtaaaaaa agctgtagtt
     8941 cgcctcgctg caccacctaa tgttagaact tcaataatta caagggaagt agcagttaaa
     9001 aatattcttt ctggtaaata tgaaggacaa aaagttctta ttgttgcagt ttctccaatc
     9061 gatgttaaat ttttgattga taacggttta ccaataacaa gtgtaaacgt aggaaattta
     9121 tcaagaagga atggaacaga acgcatccgt ccgacgataa atattactga agaagagaga
     9181 gaggctttta aagaactaat tagtgatgga gttgaagtga cagtgataca aactcctaga
     9241 gattcaaaag aatttttaaa ggattttatt tattaagaac agaggatgag tggatggagt
     9301 ttataattac atctcatgga aatattgcca ttggatttgt agatacatta aaaatgtttt
     9361 ttggcgataa tttaaattgt catgtggtaa cacttggaga tgcaggcatt gaagaattcc
     9421 gtgaaaacat tgaaaaaata gtttctcaag taaaaaatca agaagttatg gtatttgctg
     9481 acttgattgg tggaacacct ttcaacgaat ttgctaaaag aagtgaagta tttcaaaatg
     9541 ggtttcaact tcttggtggc atgaatttag gaattttgat tgaggctgtc aatttgagat
     9601 tacaaggaaa aaaaagcgat gatatcatcg aaaatctaag aaatatgaat acaattgcgt
     9661 gtcttgcaga tatgcaaaga catactaacg aagaggatga gtgataaatg caaaaaattt
     9721 tttacaagcc taaagatttt tggtttgggg attgcatgcc tttttataaa gatggaactt
     9781 tttatctatt tcatcaacga gatacgagaa atcctaaacc tttaactgat ccttttgggt
     9841 ggtcactagt tacaaccact gattttgtga aatttgaaga atacggggaa gtaattcatc
     9901 gtggtggcaa cgatgacatt gatcaataca tttacgctgg aagtattgtc caaggaatca
     9961 atgagtattt agctttgtat actggacata atcgcaaagc taagttggat ggaaaaactt
    10021 cagaagtgtt aatgattgca agttctaaag atttaattca ttggaaaaag gatggcgaag
    10081 cagcaaaact tgttcctcaa gaaggatatg ataagaatga ttggcgcgat ccttttgcaa
    10141 tttttgatca agatcatgga aaatacgttt tgatactagg agctagaaaa ccagcaagta
    10201 agaaaaagcc gacggggaga ttggtctatt ttgaatccga agatttaaaa gattggaatt
    10261 tcaaaggaga ctactgggct aataatgaat ttaacatgat tgaaatgcct gatatatttg
    10321 aaattgatgg aacgtggtat ttactttttt cagagtattg tgaagataaa aagactaaat
    10381 atcgagtcgg agcaggatta ttttcagatt ggaaatcacc agtagacgaa gctttcgacg
    10441 gaaaagccta ttatgcagca agaacagtcg gaactaatga aactggccgt tttctaactg
    10501 gctgggtggc aacaaaagaa ggggagaacg atcaaaataa ctgggattgg ggcggtgcac
    10561 ttgttccaca tcaaattatt caaaagacag acaaaactct tggtgttaaa ctgcctgaaa
    10621 aaataattga gaattttaaa gaaatcactc cattttcaag ttttaagtta gagaaagaat
    10681 ttggaaaaaa agaaagagta attgttccta aaatcgaaga ttattttcta tttgaaacaa
    10741 ctttgactat tacatcgtta acaaaggagt ttgctttaaa attatttgta gatagtgata
    10801 ctcaagaagg atacgaattt cgtatttcat tgattaataa tcagcttact ttcggaaaaa
    10861 ctccgaacta tccttggcct caaatgtttg ataaggggct gcaacgacca ctatttttgg
    10921 aaataggcaa agaatatgaa ctaaagttaa ttgttgatga tacgatagct gttttatata
    10981 ttgataatgt tgctttaagt actagaatgt atgataaagt cggaacagca ttaagtatga
    11041 ctgttacgga gggagcaatc aaggtagata aactagacta ttcaataaat tatgaatgtg
    11101 gattttaaaa caattgaagg gatgatgtaa gtgaaattaa atggtttaca acatattgga
    11161 attccaacaa aagattttgg agcttcaaaa atcttttatg aatccttagg gtttagtctg
    11221 attaatgaag aaatgaatgt gggaagtaaa gtcggctttt tcgagttgaa tggaacgata
    11281 atagaaatat gggaagataa aactactgag tgtagaggag ccattgatca tctagcatta
    11341 gatacggatg acatagatga ggtattcaat tcaattcaag atttaggata tgaattatta
    11401 gataaaaata ttatggaatt accgttctgg gaaaatggaa tccgttactt taatttctac
    11461 ggaccaaatc atgagattat agagataagc caaatgaaga aataaataga taacgaagtg
    11521 ctctaagttg gtatgaacga aaagtacttc attttttggt atcagcattt caatagttta
    11581 atgagaattt actatttcaa attaattcaa agtgacagta ttttttactt atttggtttc
    11641 aaattttgta atccttccta tttattggaa tacactccac attttgtata caagtcatat
    11701 catgttttag caaagctctt accaagcaaa gttataatga tgttttccaa agtttgatct
    11761 ttcgatggag gctaacacat attttttgca ggacagccaa aattagatgt atagaataga
    11821 gtctgtgagg cgtatagaca gtttattgtc tgtatgcctt tttttatttt gaaaaatttt
    11881 tagtattttt cgaaaaatgc tcactcctag
//
LOCUS       DARPZF010000070        11321 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.073, whole genome shotgun sequence.
ACCESSION   DARPZF010000070 DARPZF010000000
VERSION     DARPZF010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.073"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(99..1619)
                     /locus_tag="SLE65_002464"
     CDS             complement(99..1619)
                     /locus_tag="SLE65_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HEI8449720.1"
                     /translation="MTKMESELLVQIKQLTQLLEIQQQENTLLREQIAEMNRRLFGRK
                     KETPPVDGQIDLLDDSTFNEPEHTGQESQEPITVSSFKRRKRKGLKALSLEGLPEVPI
                     HYELKGADCLCEDCGHTLHDIGATRLREEPLYVPAHIEKQVIYQHAYHCRECEALGET
                     KIKKAPVPKPLINNSLGSSSIVTQSIWEKFVKKVPAYRQEKEWHALGFPLDRKKITNW
                     HIKVSEMVLEPIYNCLHQELSNQEVLHADETSYRVLNTHKEKTFYWLYASGKSEEKQV
                     VLYEHANSRSVDEPKSFLESFSGFLHTDGYAAYGKLPVNNVYCWAHVRRKFFEALGKQ
                     PSPKSHAKIGLDFCDKMFRIERTFNKLSAEERFVARKETLQPVMTEFFHWCESFAYLP
                     KSQLGKAVQYAVNHKDGLQIVLLDGRLELSNNRAERAIKELVIGRKNWLFSKSLKGAR
                     SNGIILSIIQTAVANGLNIRKYLNHLFTEIPNLSSMTPEALRAYLPWNQQIQEICK"
     gene            complement(1862..2047)
                     /locus_tag="SLE65_002465"
     CDS             complement(1862..2047)
                     /locus_tag="SLE65_002465"
                     /inference="COORDINATES: protein motif:HMM:NF017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HEI8449721.1"
                     /translation="MPMLIDATALKHIFIVCGKTDLRKGIDGLAAFVIEEYDLDVYDQ
                     ALFLFCGTKKDRFKALY"
     gene            complement(2031..2213)
                     /locus_tag="SLE65_002466"
     CDS             complement(2031..2213)
                     /locus_tag="SLE65_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449722.1"
                     /translation="MNKKDIVPVQFSSAAQKSQIDTKPKLACRIKSEDKEIFIYNGMD
                     KYLLYTLLKELNANAH"
     gene            2454..2672
                     /locus_tag="SLE65_002467"
                     /pseudo
     CDS             2454..2672
                     /locus_tag="SLE65_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            3167..3766
                     /locus_tag="SLE65_002468"
     CDS             3167..3766
                     /locus_tag="SLE65_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEI8449723.1"
                     /translation="MKTVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLADVLEISRGRVVVKDRLAMKEQKTAKHNSVYISNKLRKTILEYVQQEFPDQ
                     LLQQDFDGYLFPSRKGTNEPLNRQSLWRIIHDAGTAIGLKDIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            3830..4429
                     /locus_tag="SLE65_002469"
     CDS             3830..4429
                     /locus_tag="SLE65_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage abortive infection AbiH family
                     protein"
                     /protein_id="HEI8449724.1"
                     /translation="MSTLYIIGNGFDLSHGLKTRYTDFSKWVEKSHSEIFDKIDTMIN
                     ENNEVRSTADDKIGWFNFESSLHELIQSPVFEDYVEESKDYLIGYGHEDWSDSAHHDF
                     QNMVYDYVVSLEELQQLFKEWIRKEIQPTIEHKIPKYQFSSDVLFFTFNYTDVLEILY
                     KQPKENIYHIHGSYDDIIIGHSENFDNFIGDPVLLQSFK"
     gene            complement(4459..5110)
                     /locus_tag="SLE65_002470"
                     /pseudo
     CDS             complement(4459..5110)
                     /locus_tag="SLE65_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            complement(5445..6317)
                     /locus_tag="SLE65_002471"
     CDS             complement(5445..6317)
                     /locus_tag="SLE65_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEI8449725.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
     gene            complement(6581..8527)
                     /locus_tag="SLE65_002472"
     CDS             complement(6581..8527)
                     /locus_tag="SLE65_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEI8449726.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKINGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            8712..10151
                     /locus_tag="SLE65_002473"
     CDS             8712..10151
                     /locus_tag="SLE65_002473"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HEI8449727.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            10153..11115
                     /locus_tag="SLE65_002474"
     CDS             10153..11115
                     /locus_tag="SLE65_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8449728.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
BASE COUNT         3677 a         2041 c         1972 g         3631 t
ORIGIN      
        1 ataattcagt agttttgagc gtaagcgtgt catagaatgg tacctaaaca caaatagccc
       61 gatttgatac actcaaatca ggttatttgt ggcttatatt atttacagat ttcttgtatc
      121 tgctgattcc atggcaaata agcgcgtagc gcttcaggtg tcatcgaaga cagattggga
      181 atctctgtaa aaagatgatt taaatatttg cggatgttta acccattcgc aacagctgtc
      241 tggataatac tcaatataat tccatttgat ctagcgcctt ttaagctttt agaaaatagc
      301 cagttttttc gaccgatcac taactctttg atggcacgct ctgctcggtt atttgaaagt
      361 tccaagcgtc catcaagcaa cacaatctga agtccgtctt tatgattgac tgcgtattga
      421 accgcctttc caagctgcga ttttggcaaa taagcaaaac tctcacacca atgaaaaaat
      481 tcagtcatca caggctgcaa cgtttccttc ctcgctacaa acctttcttc tgcgctaagc
      541 ttattaaagg tccgttcgat tcgaaacatc ttgtcacaga agtctaatcc tattttggca
      601 tgactttttg gggacggttg tttacccaat gcttcaaaaa actttctgcg aacatgcgcc
      661 caacaataaa cattgtttac cggcagcttt ccataggccg cgtaaccatc agtatgcaag
      721 aaaccgctaa atgattctaa aaaacttttt ggctcatcaa cggaacgcga atttgcgtgc
      781 tcgtagagca caacttgttt ttcttcgctt ttacctgaag catataacca gtaaaaggtc
      841 ttttctttat gagtattcaa tacccgatag cttgtctcat ccgcgtgtaa gacctcctga
      901 ttgcttaatt cttgatgaag gcaattgtag attggctcta aaaccatttc acttaccttg
      961 atatgccaat tagtgatttt tttacgatca agagggaaac caagtgcatg ccattctttt
     1021 tcttgtcgat atgccggcac ctttttaaca aatttttccc aaatactctg tgtcacaatt
     1081 gaagaggaac ctagactatt attgatcaac ggtttaggaa caggcgcttt tttgattttt
     1141 gtttctccta atgcttcaca ttctctgcaa tgataggcat gttggtagat gacttgtttt
     1201 tctatatggg caggaacata caatggctct tctctaagcc ttgtcgcacc gatatcatgt
     1261 aaagtatgac cacagtcttc acacaaacaa tcggcacctt ttaattcata atgaatagga
     1321 acttcaggca gaccttctaa tgaaagtgct ttgagtccct tgcgttttct gcgtttaaaa
     1381 gaagataccg taatgggttc ctggctttct tgtccagtgt gctctggttc attaaaagtt
     1441 gagtcgtcta ataaatcgat ttgcccatct acgggtggtg tttctttttt tcgtccaaac
     1501 aagcgtcgat tcatttcagc aatttgttct ctaagaagag tattttcctg ttgctggatt
     1561 tcaagcaact gtgttaattg cttgatttgt acaagaagtt cagattccat ttttgtcatt
     1621 tttacaccac cattctagcg attttcttac atctattata ccattttatg acaacgaaaa
     1681 acagacaaaa tccttgattt aacaaggttt tcgtctaata tatcgcacct tttttcgttt
     1741 cttttagcgt acatttttct tcgattgaaa ggccagtcag taagacttct tttctggaac
     1801 gcggccattg aaggtaccca ctttcaaatc ttttgtacat taatacaaat ccattttgat
     1861 cctagtaaag agccttgaag cgatctttct tcgtaccgca aaataagaaa agcgcttgat
     1921 cgtaaacatc aaggtcatat tcttctataa cgaaagctgc tagtccatca attccttttc
     1981 gaagatctgt ttttccacaa acgataaaaa tatgtttcaa tgcagttgca tcaatgagca
     2041 ttggcattca actcttttaa caaggtatac aaaagatatt tatccattcc attataaata
     2101 aatatttcct tatcttccga tttgattctg caagctagtt ttggcttggt gtcaatttgc
     2161 gatttttgag ccgcacttga aaattgaact ggtacaatat cttttttatt cattcgtttt
     2221 tctccttcta tatttgatag tttaattata gaagaaagat aatcggcgta cgagatacta
     2281 tcctatgaca cgcttacatt taatttaata ttttgcctca aattagccac actttttata
     2341 gaactaagag gaaaaatgaa gttttcttcc tattaatata gttgtttgaa atcttaaata
     2401 tagcgtttta cgatgtaatg ggaagtatgg tgaataaatc aactatgttc gtacgaagca
     2461 tttactcaac taatttaatc gaatctttca ataaacaaat caagaaatac agccaccgca
     2521 aggaacagtt ccaaaatgaa gagtcgatgg aacgtttctt agtctcgtct tttgatactt
     2581 acaaccaaaa attcctaggt cgcagtcata aaggtttcca acaggccgaa ggcgagctcg
     2641 aacaaatgct gagtcaaccg atggagaatt agaaacaatc tacagtaggg aagaaccatt
     2701 gacacaaaat tattgacgct cccaactaaa agtgtcaaaa taatgatgaa atcatttagt
     2761 tcttataaat tagaaaagag aaaataaata ttccatatct actttattgg atccgtaaca
     2821 tgactaaatt ctgaatactt tttaaagctt atcatttggt aaaactgaat ataagttaat
     2881 tatatagact gaaaattttg aattttcaga atagaataac ttaaaagtac tgacaaaatt
     2941 ttttaaaggg gcaatattaa tgttctgaga taatcaaatc ctaccgaaaa tatcaaaaat
     3001 ccaatgtgac acaatcagat tgtgtctcat tcgagggaat cacacaatcc cacgtggctc
     3061 taggcagaat tgaatttttg cttggggctt tttccttata ttgattttga atgagactta
     3121 ttatatgtta taatgcaatt aagtatcatt ggagagggcg aagaaaatga agacggtaga
     3181 acctattcga gacaaaaaaa agatcgatgc gatgaaggca atcttggctt cgggaaaata
     3241 tggccaacga aatttggttc ttttttcgat tgggatcaac accgcctatc gcatttctga
     3301 tttgcgtcaa ttgaagctgg ccgacgtgct ggaaatttca cgcggtcgcg tggtggtcaa
     3361 agatcgatta gcgatgaagg aacaaaaaac agctaaacat aattcggtct atatttccaa
     3421 caaattgcga aaaacgattt tggagtacgt tcaacaggaa tttcctgatc aactccttca
     3481 gcaagatttt gacggttatt tgttccctag tcgaaaaggg acgaatgaac cgctcaaccg
     3541 ccaaagtctg tggcgaatca ttcatgatgc tggcacggca atcggattga aagacattgg
     3601 cccacattcc atgcgaaaaa cgttcggtta ctttctctat aaacagggga ccaaaacaga
     3661 aatcattcag tccttgttga accattcttc tcagcgcgaa acattgcggt atattggtat
     3721 tacacaagaa gacaaagata cagctgtaaa aagcttagat ttataatata aaagttaagt
     3781 ttaaacatgg atagttttaa attagtagat tgagtgttgg gaggaaagaa tgagtacatt
     3841 atatattata ggaaacggtt ttgatttaag tcatggttta aaaactagat acactgattt
     3901 ttcaaaatgg gttgaaaaaa gtcatagtga aatattcgat aaaatagaca caatgataaa
     3961 tgaaaataat gaggtgagaa gtacagctga tgataagata ggttggttta attttgaaag
     4021 tagtttgcat gagttaattc aaagtccagt ctttgaagat tatgtagaag agtctaagga
     4081 ttatctcata ggttatggac atgaagattg gtcagattct gcccatcatg attttcaaaa
     4141 tatggtttat gattatgttg tttctctaga agaattacaa caacttttca aggaatggat
     4201 acgcaaagaa atacagccga caatagaaca taaaattcca aaataccaat tttcgtccga
     4261 tgtactattc tttacattca attatacaga tgttttggaa attctataca agcaaccgaa
     4321 agaaaacata tatcatattc atggcagtta tgacgatata ataatcggcc actccgagaa
     4381 ttttgacaac tttataggag atccggttct gttgcaaagt tttaaataaa gaataaaatc
     4441 ccttacggta tctatgattt aagctgggat tcccaataat accttgattt cagtacagac
     4501 cgaaaacccg aagagagtgc cttcttttcg ggttttctta tataatcctc gaatggcttc
     4561 catgccttta atcgtggtag aggcagtgcg taaacttcga tagaatttat tgcgtctctt
     4621 tactggacga tggtcttgtt caatcaaatt attcaggtat ttaatggtac gatgttctgt
     4681 cccttgataa aagccgccgt attcttttag tttcttaaag gcacttgtaa tagagggggc
     4741 tttatctgtg actacaacct tcggttcatc aaactgcttc actaaccgct taagaaaagc
     4801 atacgctgct tgtgtctccc gttttttacg taaccaaata tccaaggtta aaccatctgc
     4861 atcgatggct cgatacaaat aatgccattt tccatgaata aaaggatttt ttatttttct
     4921 ttttccaaat ttgatagagt agtttgccat attcttgcac ccaacgataa atcgtcgtat
     4981 gagaaacgtt aatgccacga tcatataaga tttcttgaac ttcacgatag ctaaggttat
     5041 aacgaagata gtagcccacg gctacaataa tcacatcctg ctgaaattgc tttcctttaa
     5101 aatgattcat cgtcattcct cctgctatct ttttctatta ttctacctta tttgatagta
     5161 gatttaaaac tttgcaacag aaccggaaga agcaaagata tatttgttaa aaaggtccaa
     5221 aaaaatatcc gcaccccctt ttttttgtaa aaaactattg cacaatacaa gtggcctacg
     5281 gctatcgaaa tttccataac tttcgagcaa gaatttatct cattcaaggc ttgatcttcc
     5341 aagtaaaaca aaaaccagtt aagcactctg cctaactggt tatgactaaa ttttcagttg
     5401 tatctttctc taccaacact aaatgtcgaa gagccttttt tcgtttatga atgtaagacc
     5461 gcttctcgag ccaatgccaa acaaccgagc gttccagcgt tgtcttctaa tgctggggtc
     5521 acgatatatt tgcttaactc aggtgtttcg acatacccat tgaccaattt tgcaaatgcg
     5581 tcgtggacgt tttgcagcat atggcgttgt ttcatcacac caccgccaaa aatgatcaca
     5641 tctggagaaa acatcaaggt tgtattgtag gcacattgag caatatagga ggcttcgatt
     5701 tcccaataag gatcatcttc tgcaacctct tgtccttttt tccctaagcg gttttcgatg
     5761 gcgggtccag cggccatccc ttctaaacag ttgccatgaa atggacagct gccagcaaag
     5821 tcatcttttg gatgagggac gacgagcata tgccccattt ctggatgact aaacccttcg
     5881 ataaagcgcc cttcttgtaa ggcaccgccg ccaacacccg taccgatcgt atagtaaacg
     5941 acactgctca atcctttgcc actgccgaag acatactcac cataggcagc cgcattgaca
     6001 tctgttgtcc aagaaatcgg gatcggaaat tcttttttca tggtaccgat gaaatcaaaa
     6061 ttttgccatg ccaatttcgg ggtcgaggta atgtacccat aagtggcgga atcgcgatgg
     6121 atatcgatag gcccaaatga gccaatccca atccctgcta aatctgcttg gtattgtttg
     6181 aagaagtcaa tgactaaagg cattgtttcc tcaggtgtcg ttgtcggaaa gctcactctt
     6241 tccttgatcg tcatttcttc atcgccaatg gcacacacaa attttgtgcc gcctgcttca
     6301 attgcaccgt atagcataga catttctccc tttattttag aatgaaatca ctaaataaat
     6361 gactatatat catatttaaa ttattttttt atttagtaac atgacaagta aataactact
     6421 attttttctt tttgaatttt tatcattttt taaaattcta ataatttttc atacaattga
     6481 tatatgaaaa gattaaataa aatgttattc tcaaatattt gattaatcta tattatttga
     6541 ttttggaaag aaaattccat ctttactcag ggaaatatat ttatttgatt tcaagtaaat
     6601 cagtaccctc agtgactgta ttttcagcta ctatatttac ttctgaataa tccgaagtat
     6661 tggtcacaat aatcattgtt gtatcatcaa gaccttcttt ctcaatcatt gaacggtcaa
     6721 atgctccaag aatatcgcct tttctaactt tttgattagt agtaactttt tgtgtaaatc
     6781 cttttcctcc cattgataca gtatcaatac caatatgaat tagaacttca gcaccattat
     6841 ttgatttaat accataagca tgtccagttt caaacgtgag ttgaatagta ccatctactg
     6901 gagaatggac cgtgtttcca tttggtttaa tggcaatccc ttttcccata gcttctgatg
     6961 aaaagactgg atcatttact gaagaaagac taatcacttt accagaaatg ggactaacaa
     7021 ttgtttctga tgaaactttt gtttgtgttg attcaacatc agtagatatt ggatctgttg
     7081 ttgctacttt tgaagaatta actggtgttt gttcagcaat ttcttctgct ttaaagatac
     7141 cagcagcttt tgttttaccg tagaagtaag taattgcaaa agcaactaca aagctaatca
     7201 attcacacaa tacgtaaaat ggaatagatg ttgcattaat tgaaagaaat cccaagaaac
     7261 ctgctgaacc aagtgaaaca gcaactactt taagtaatcc tgctactgct gtagcaattc
     7321 ctgaaccaat taaagcacaa aagaatggaa agcggtattt taagttaact ccgaacaagg
     7381 caggctctgt aattccaaga agtgctgaga cacccgcaga ggaagcaaga ctttttgtct
     7441 tagaattttt agttaagaac caaatggcaa atgttgcagc accttgagca acgtttgcca
     7501 tagatgcaac tacaaagata aagtctccat gtccgatacc atttgtccac gctgaaagta
     7561 attgagtttc aatagctgga aatgattgat gtaaaccagt catgactata agtgaatatg
     7621 ttcctccaaa aatacccatt ccaataaatc cagtagtgtt atatagccaa acaataatgt
     7681 ctgtaattcc attagacaac aataacatta cagggccaat aactgtgaaa gtcaaaaatc
     7741 cagtaatcat tactgataat aatggcgtga atgtaaagtc aatagatgat ggcaattttt
     7801 tatgaaagaa tttttctaat atagataata tccaaacagc tgctaaaact ggaataactt
     7861 gataagcata gtttgtttgt gaaacatgat aaccaaaaat attccaatat tcagttgagc
     7921 caccaagatc tggtgttgtc atgatcatac caattgcagc accaagaaat tggtttgctc
     7981 caaaacgttt agcagctgaa atacctacta aaattggtaa gaacatgaat ggtgcagcgg
     8041 acatcagttg gatcattgag gaaatacctt caatcgcagg atacatttct tcaattgatt
     8101 ttggtccaaa aagtccagca gctgttaaaa agttttgtaa tgccattaat aaaccacctg
     8161 caacaagggc aggtataatt ggaacaaaaa tatctgataa taatttaatt aatgccataa
     8221 tggggttgaa ttttttatct ttactagcaa tttgttttaa atcatctgtt gaaatttccg
     8281 aaagtccagt ttttttgata agttcgtcat aaacgaaatt aacatcacct gcaccgataa
     8341 tcacttgata ttgtccatta attttaaatg tgcttttcac atctggattt tcgtctaaag
     8401 ctttttgatt cactttcgtg tcatctttta gtacgagacg aagacgtgta gcgcagtgtg
     8461 cagctgcaat aaggttatct tttccgaccg cttgtattac gtcggaagct actttactgt
     8521 aattcattcg aatcactcct tttttatttt tacgtgaaaa cggttcactg aaatgcaaat
     8581 ttattttagc atatcttaaa aatatgtcaa acgtttgtca tatagtttat ttttttaaat
     8641 gaaatgattg atttttcaac ggaaaacgtt taccatacta gttgtaaaaa gataaattga
     8701 aggagtaaaa tatgaactta cctcgagaaa tacgatatcg tgcttattct gattggacta
     8761 aagatgagat ggataaaatt aaggataatg taaaacgatc accttggcgt gctagctatc
     8821 atatcgaacc taaaacagga ttgttaaacg atcctaatgg tttttctttt tttaacggaa
     8881 aatatacgct tttttatcaa aattggccat ttggagctgc tcatgggttg aaagaatggg
     8941 tacacaatga atcagatgat ttagttcatt ttcatgtaac aggagcagaa cttcttccag
     9001 acacaaaacg agatagccac ggcgcttatt ccggttctgc atatgaaata gaggggaatc
     9061 tattcttact ctatacagga aacgttcgaa atgaaaattg ggaacgtgat acacttcaaa
     9121 tcggagcatg gatggataaa gactacaaca ttacgaaagg tgagaatgtt cttattcata
     9181 aacctgctga tgtaactgat cattttcgtg atccacaaat gtttaattat gaaggacaat
     9241 tgtatgcgat tgttggagca caaaatttag aaaaatcagg ctttatcaaa ctttacaaag
     9301 cggatgacaa taacgtggaa acatgggagg aagttggcaa ccttgatttt ggcggcactg
     9361 gttcagaata catgattgag tgtccaaatc tagtatttgt agacaaaaaa cctgttctca
     9421 tttattgtcc tcaagggttg gataaatctg agctaaatta tgggaatatc tatccgaata
     9481 cttttaagat ctgtcaatcg cttgacatag aaaaagtaaa acttgtgggc gcttcagaaa
     9541 ttcaaaatct tgattatgga tttgaagcgt atgcgactca aggattcaat actcctgatg
     9601 gtcgtgctct gattgtcagt tggattggac tacctgatat cgattatcca actgataagt
     9661 atgattatca gggagcaatg agtcttgtaa aagaactttc aataaaagat ggtaaacttt
     9721 accaatatcc agtagaagct attacatcat tacgtgctag ttctgaacaa tttacagcaa
     9781 aagcagaaac aaataatact tatgagcttg aactaacttt tcctccaaat cagaaatcgg
     9841 agttacttct tttctctgat agtaaaggaa atggacttag cttgattgta gataccaaag
     9901 aaggaaaaat tattttagat cgcagcaaag caggcattca atatgccact gactttggta
     9961 cgattcgtga atgctcaatt gatactaaag aaacaactgc taacattttt gtagataact
    10021 caatcattga gatttttatt aataaaggag aaaaagtgtt tactagtcgt gtattccctg
    10081 aaaatcacca aaatggtatt caaatcaaat caggcgaacc tactggaaaa tactttgaat
    10141 taaaatatta aaatggtagc aaaattaact gatgtcgctg aattagctgg agttagccca
    10201 acaaccgttt cacgcgtcat taataataag ggatatttat cagaaaaaac aaaacaaaaa
    10261 gttcatgaag ctatgaaaac tcttggttat aaaccaaata atttagcacg tggacttcaa
    10321 ggaaagtcac ctcagcttat tggtcttatt tttcctaata ttagtaatat cttttactct
    10381 gaactcattg agtatctcga aatagagtta tttaaacatg gatataaaac gattatttgc
    10441 aatagtcaaa atgatcctgc taaagagaga gaatacattg aaatgcttga agccaaccaa
    10501 gttgatggca taatctcatc aagccataat cttggaattg ctgattatga gcgtgtgaga
    10561 gcacctattg ttgcttttga tagaaattta gctcctaatg tttccattgt ttcttcagat
    10621 aactttgaag ggggaaaact tgcagctaag actttacaaa aaaatggttg tcaaaatacc
    10681 attatgatta caggaaatga taacacggat tctcccacag aattacgtgc actaggtttt
    10741 tcttttcaaa atccaaatgg aaaaattttc aaaattccta ataatctgtc tactatccgt
    10801 cgtgaaatgg aaataaagtc aactattata aatcacaaac cagatggtat ttttgtttct
    10861 gatgatttaa cagccattct cactatgaaa attgctcatc aacttaaact taatatccca
    10921 gaagatttaa aaattattgg atacgatggt acctctttta ttgagaaatt tttcccacaa
    10981 ttgacaacaa taagacaacc aattgatgaa attgcaagtc ttattgttga tattcttctg
    11041 aaaaaaatta aaggcgaaaa gacaaataag gattatattt taccaatctc aatactttct
    11101 ggaggaagta tttaacgtta aattaatttt ttaatgtcta taaaattcgt tagaaaatac
    11161 aatttgtaga tatccaattg atttgtaaac aaaaaggagt tgtcaacttg tagtgacccc
    11221 caaaagttag acttttttgg agtggagaaa tccactcctt ttttcatgct ctaaaatgat
    11281 atttttacac aactgttacg gttgttttac gaaattggac g
//
LOCUS       DARPZF010000071        11275 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.074, whole genome shotgun sequence.
ACCESSION   DARPZF010000071 DARPZF010000000
VERSION     DARPZF010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.074"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(51..560)
                     /locus_tag="SLE65_002475"
     CDS             complement(51..560)
                     /locus_tag="SLE65_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449729.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(550..1275)
                     /locus_tag="SLE65_002476"
     CDS             complement(550..1275)
                     /locus_tag="SLE65_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449730.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(1498..3618)
                     /locus_tag="SLE65_002477"
     CDS             complement(1498..3618)
                     /locus_tag="SLE65_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEI8449731.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            3848..5026
                     /locus_tag="SLE65_002478"
     CDS             3848..5026
                     /locus_tag="SLE65_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEI8449732.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            5042..5800
                     /gene="aroD"
                     /locus_tag="SLE65_002479"
     CDS             5042..5800
                     /gene="aroD"
                     /locus_tag="SLE65_002479"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEI8449733.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            5823..6308
                     /gene="ybaK"
                     /locus_tag="SLE65_002480"
     CDS             5823..6308
                     /gene="ybaK"
                     /locus_tag="SLE65_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HEI8449734.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(6379..7632)
                     /locus_tag="SLE65_002481"
     CDS             complement(6379..7632)
                     /locus_tag="SLE65_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEI8449735.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            7749..9098
                     /gene="gdhA"
                     /locus_tag="SLE65_002482"
     CDS             7749..9098
                     /gene="gdhA"
                     /locus_tag="SLE65_002482"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEI8449736.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            9210..10556
                     /locus_tag="SLE65_002483"
     CDS             9210..10556
                     /locus_tag="SLE65_002483"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEI8449737.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(10864..11250)
                     /locus_tag="SLE65_002484"
     CDS             complement(10864..11250)
                     /locus_tag="SLE65_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEI8449738.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3666 a         2021 c         2292 g         3296 t
ORIGIN      
        1 atcatgaatc gatcttctat accgcttgtt tttactataa aatgattgat ttagcccgcg
       61 ggctctaaac gatcaatata aggactttga gcaatagtag catcatgagt aaagagtaag
      121 ataccttgat tttcttcatg agctaaataa gaaagcaagt ggagtagctc ttggatctcc
      181 aatacactaa gttcatcaaa tgtatcttca ataacaatat tgtttcgctt ggaaagcaag
      241 gcatgaagta attgcagctt tactttttca aaagacgtca actcagctgc cgcacaatta
      301 agcaaggaag gagagatatc aagtttttct tgataggcca aacgatcttg tttgatttct
      361 ttttccggta catccaacag gacatggtct ttaagattca gataaggaaa catcggccaa
      421 tttttttgga tgatcgcaaa attatccagt tttgcaacaa gaacctcttt tttcaagtgc
      481 tccaatattt tatgctgttt ttcgagagga cacaaaataa cggtcaagtg ttcagcatga
      541 atcaaatatt caggtttcat tacgtccagg cctcctactt tgcaaatgat ggataaaaaa
      601 agtgaaaggg aatagactaa gaatgagaca gcatccactg agcccaataa gagtttgggc
      661 aaatccctta agtatatctg tgaaaaaaag atcattttgg aaatcgatgg taaaaaaagt
      721 ctgttgatcc atcggaattg taagtccgct taccgaagtc aagatatcac ggatatctgg
      781 cagttcagta gtctttaaga caagaaaatt gatcctttga agaagcgctt cataaactga
      841 ctggaagctt acgatccaca ataaaaccaa gatacaacaa agaaagagag gaaagaacag
      901 ctgccagaaa ataaaaagga ataatttggt tttagaaaga ccagtcaggt gccaattgat
      961 caattcctgc ttgttttgcc tgactgaata gtaaaagaaa aagataaaaa ggaaggcaaa
     1021 tagaaaaaat aaactgaata tgccttttat ataaaatcgg ctagctaatt ctaaagccgg
     1081 aagaagctct gtagatgcag aagcgccaat aaatgaaagc cgatcttgga cttgattggc
     1141 taaagccgat tgcaaatggt aaagagtcag gcatgctatc aataaaaaag cagaaaagct
     1201 tgaaaataaa caatagagta ttgtctgctt tttgtaataa attaatcgag cagtagcata
     1261 gcggattatt ttcatacttt tcacctctat aaaaagtata gaaaatgaat atgaataaag
     1321 tatgaaattc ctttagtgaa atcacgaatt aaaaccagaa aatattttgt aaaaagcaag
     1381 aggttgtgaa gaagctgccc tattctatta ccgtagatgc aagcttttga acactgttta
     1441 ttcgaaaaga ggagcagcga caataatttt gtcgctgctc cttttaaatt tattttatca
     1501 ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac gtttgcgttt tataaagatc
     1561 aacagttgat tgtccgttgt gttcactaaa gacactagtt gacttgtcac caagagattt
     1621 ttcagcttct tttaatttct ctaagccatt cttgtagtca taatcactgg tatcaattgg
     1681 gtctaatcca ctattcgtat agaaccgaag aagatcacca ttattgattt ggtcagaaac
     1741 agctaactgt ttatcaactt tttctttcag tgaatcaatt tcattctgta cttcctcagt
     1801 aggttcagta atagcttcac cagtttcgtt actatagatc gtaccaccgt agtaagtata
     1861 ttttggtgta acaaaatcac catcacggaa agaaacaagc tgttcatgat ctttcgagaa
     1921 tagatcttgt cctaactgaa tataattttt tgtatctaca cctagtaagt gaagtaatgt
     1981 aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt ccgccctgtg tttgtccagg
     2041 gatatggatc atataaggga cacgctgcat ttgtgcattg tcgtagtttg tccaagtaga
     2101 acttgttttt ccaactaatt cagctagatt tttatttctt gaattcgaga caccgtaatg
     2161 gtcaccgtaa aggacgatga ctgaattatc atacaagccg ctttctttca aataattgaa
     2221 gaattcttgt acggcggtat ctaaataatt ggctgtcgca aagtaaccgt tgatcgtttc
     2281 atcatttgta ttggctaacg ggaatcctgc ttcgtcattg gtgaattttg aataaggata
     2341 atggttagat acagcaatga attttgaata aaatggttgt tgcagacgtt ccaagtattg
     2401 tacggattgt tggaaaaatg gtttatcatg caacccgtat tggaacgaat tgtcatcatt
     2461 aacatcataa taagaagaat caaagaaata atcatatcct aaattcttgt atgtctcgtt
     2521 tcgattccag aatgtaccag cgttcccatg gaataccgca ctaatgtaac cttgtgtttg
     2581 acttaaaata tcaggtgcag cttggaaagt attttttccg cctaattgtg tgaacaagga
     2641 gccttgattc aagccaaaca atgaattttc catcagcgtt tccgcatcgc ttgtttttcc
     2701 tgcttttact tgatggaaaa agttgtcaaa actgaacgtg ctgttgctgt ggtaaagact
     2761 attgatgaaa ggtgtaactt catgctggag accattctca tctgtcaatt tataatcgat
     2821 caggaattgc tggaagcttt ctaaatggat ataaatcaca ttttttcctc tagcgagccc
     2881 gaacaaatcg tcatttggtg ctgcataatg ttcttttaca taattttcta cttctttcat
     2941 atcattggga cttgcttctg cccgcacttg gtttgtctgg taagtttgaa caccgtcata
     3001 aaccatgaaa gcattcaagc caagatattt gaccaaataa tcacgagaga atgttcgagt
     3061 cagcaattct ggacgatcag cttccgccat aaaaagattt cctgagaaaa tcataactgc
     3121 taatgtagag atcgcaaaag ccattcttgc tcggatcggg cgagggtcca acttgatttt
     3181 ttttgcaatc agcagaacag tcaagataat aaaatcgatc caatagatca catcatatgg
     3241 gcgaaacagt cgaatggcac tttctcccag accactcgct actttcccag cacctaaaat
     3301 cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa gtgacattcg aaaaaacaag
     3361 caatgtcaaa agaaaataaa tgaccatcat cgtgatataa gcaactctag ggcgtctgat
     3421 ataaagagca attccaagta ataacaatgt agttgcaata gggttgataa acaagataaa
     3481 gtattgaatg ccactttcga ttccgagatg gaaatcaact aaataggcaa aaatcgtttt
     3541 caaccaaagt aaaacgacta gtaaagaaaa aaatccgagc ctcttattca aaaaggcagg
     3601 tgtttttata catttcaaga taatcttcct ttctgcactt cttaatcaca gaagtgtcct
     3661 gaaaccatgt tacacagctc acttattctc atttatttta ctagtatgac aatatagtgt
     3721 caattgaaac cagaagttta tgctgtttca ttaaggtttt ctttaagctt catgaaaaaa
     3781 tgagcagtaa gacaagtcct atgttttttg ttatacttgg gaagagaaag ctaaagcagg
     3841 tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat cgattgaaaa aaggatatcc
     3901 actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa accacgcaat gggtggaatt
     3961 agttgattcg caaaaccaat ttatcgcaaa aggatatcta ggaaagcaga ataagggaat
     4021 cggttgggta ttgagccagc agaacatccc atttgatcaa tctttttttg aagaattttt
     4081 tgtgaagtca aaagaaaaaa gaactttctt tttttcagat gattctacta ccgcttttcg
     4141 tatattcaat ggagaaggag acgggatcgg cggtctgatt gttgattatt atgcaggtta
     4201 tgctgttttt tcttggtata acgaaacgtt atatgcacat cgtgaattat tgattcaagc
     4261 ttttcgtgaa atctacccgg aaatcatagg aggctatgag aaaattcgat ttgaatcagt
     4321 aaatctgcct gagagccagt tcatttacgg aaaagaggca ccggaaccct tgatcgtaaa
     4381 agaaaacgga gtaaaatttg ccgtttattt aaatgaagga ttaatgactg ggatcttttt
     4441 agaccaaaaa gaagtacggg gatcattagc agaaggtttc gcttctggga aaacagtttt
     4501 gaacatgttt agttataccg gcgccttttc tgttgctgcc gcaatgggag gggcaatcga
     4561 aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa acacaggaac agtttgaagt
     4621 gaatggtttg gatgtcgatc agcaaaaaat cattgttatg gacgtattcg agtatttcaa
     4681 atacgccaaa agaaaacaat ttttatatga catgattgta ttggatccac caagttttgc
     4741 cagaaataag aaaaaagtct ttcgcgtagc aaaagattat ggggaactgg tcaaggatag
     4801 tctggatatt ttagcagaag acgggatact tattgcgtct acaaatgctg cgaatgtctc
     4861 gatagaacaa ttccaaacaa tgattgaaga ggaattccat gccaaaaatg tttcttttga
     4921 acaacttgct ttatatcgtc tgccaaaaga tttccagacg acggatacct ttttagaagg
     4981 caattatctg aaagtgtttg tttatcaaat taaaaataac cattagaagg agcgatgcag
     5041 aatggttcgg gtaaagggat tgaatatagg aagcggtaga ccaaagattt gtgcgcctct
     5101 tatcggggcc gtccgagagg aagtattacg tgaagcagtt cttgcacgtg aagcaggggc
     5161 cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt ttttcttttg atgaagtagc
     5221 agaaacattg gttcttatcc atgagatgct tgatggactg ccgttattat ttacgtttcg
     5281 taccttagct gaaggcggag aacaagacat atcgatccgt cagtatcgcg acctttatga
     5341 acatgtgata cacacaggat tagtagatat ggtcgatatc gagttgttca aagtagaaag
     5401 tctaggaaaa agactgatag aggaaatcaa gtctttaaac attcctttaa ttatcagtag
     5461 tcatgatttt aaagaaacac cagcagaccc tgtcttgctt taccgattga atgttatgga
     5521 acattttgga gccgatatcg gaaaactggc agtaactccc aataatgaac gagatgtttt
     5581 gcggttgatg gagttgacta gacgggcaaa tgcttttgtc tccatgccta ttattacgat
     5641 gtccatggga aatcttggta aaatttctcg tctggttggc ggaacgacgg gttccgttat
     5701 gacatttggt tccttaagca gcgattctac ttctgctcca ggacaattac cggtcaaagc
     5761 attgaagcaa attattcaat tattaaatga accgttgtag aacaagtttg aggtgatatt
     5821 ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg tatggtcgaa caaaaaaaga
     5881 ttccctatac agagcacgaa tatgagtggg acgaaagcca cctaagtgcg tcatcggtcg
     5941 ctgaacagct tccagaaagc caatctcgta tatttaaaac actggttgct gtgggcaatg
     6001 tgacggggcc tcttgttgct gtgataccgg gagaagccga attgaatcta aaaaaattag
     6061 caaaagtttc agggaataaa aaagtagaaa tgctccattt aaaagatttg gaagcaacga
     6121 ccggatacat acgtggtggc tgctcgccta taggtatgaa aaaactattt cctacttatt
     6181 tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc ggctggcaga agagggctac
     6241 agatggagtt agcacctcaa gatatctgtg cattaacgag cggacaattt gcagatataa
     6301 aacaataaat catacgtata aaagaaagaa ggaggccggg atgttgtttg tccagtctcc
     6361 ttctttcttt tttatacatt atgctctttg cccggcattc attcctgcta catgccctgt
     6421 agcgaaagcc gctgtgatat taaagccgcc agtataacca ttgacatcca gtaattctcc
     6481 cgcaaaatac agaccatcaa tgattttact ctccaatgtt ttaggataaa tttcctttag
     6541 agaaacccct ccgccagtta caaatgattt ctcaatagga aaagttttgt tgattgatag
     6601 cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt ttttgagagg cttgttgtcc
     6661 tgtcagatga tccatttcaa gccgctcaag aaagaaaact aacaatcgct caggcaatat
     6721 accatgccaa gcattgacca agttcttttt ggttgcttta cttttttctg tcaatatatg
     6781 aataagctct tgtttggttt gtgtagggaa acaatccaga gaaagtgtca ctggttctcc
     6841 cgttttctct aattctttat tgacaaaact tgaacaacgc agtgcagccg gaccagaaat
     6901 accgaaatgg gtgaaaagta aatccatcgt atgttcagtc aatacacgac cttttttatt
     6961 taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga agtgttttct cctgaatata
     7021 cggttcatcc gatatcaagg gggactctgt cgcataaaga ggcgtcaccg tgtgacccac
     7081 tcgcttcacg atcttgtacc catctccagt agaaccagta gatggataag tccgtccacc
     7141 agttgttaag ataatggcag gagcatggaa ctcttcgaat tccgtgcgta taccgtaaat
     7201 tttatgttct ttgtggatca atttctctac tcgagtagag aatagaagcg tcacatctag
     7261 ttctttcaga cgattgagca atgcttcgat aatcgttttt gatttatttg ttacaggaaa
     7321 catccgtcca tgatcctctt cttttaaatg tacgccttgt gattcaaaga agttcatgat
     7381 atcgaaatta ttccattgcg caaacgtact atataaaaac tttccatttc caggaatatg
     7441 tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg caccgaccac cacctgtcat
     7501 cagtagtttt tttcctgctt ttttgttttt ttcgatcaag agtacgcgtg cgccttgttc
     7561 agctgcactg atcgctgcca tcatcccgct tgttccagcg ccgactacga tcacatcata
     7621 cagtttttcc attccctcac ctcaaggaaa gtgtagcata tctgaagaaa gaaaacagaa
     7681 aaaaatgttt tgagccaaaa gagaaaatga gctaaaatga gggaagataa gcaaaggagc
     7741 gtggaacgat gacaaacgca acagaatatg ttcaagcaat tcaagaaaag ctacatcaaa
     7801 aggatcaagg gcaagaagaa tttttacaag caatcgatga attcatgccc acggttatgt
     7861 cttttttgga cactcatccc gaatatatcg aaaagaatat cttagaactt ttaacggaac
     7921 cagaaagagt tattcaattt cgagtgcctt ggcaagatga tgaaggaaac tggcgagtaa
     7981 atagagggta ccgtatccaa tacaactcag ctatcggccc ttataaaggt ggattgcgct
     8041 tccatcctag tgtcaatcta agtatcttga aatttttggc ttttgaacag attttcaaga
     8101 atagtttaac cggtctgcca atcggtggag gaaaaggcgg aagtgacttc gatcctaaag
     8161 gaaaatctga taatgagatc atgcgttttt gtcaaagttt catgctggaa ttgtcaaaac
     8221 atatcggccc atcgattgat gttcctgcgg gagatatcgg tgtaggagct agagaaatcg
     8281 gctatttgtt cggcgaatat aaacgattga aaaaatatga tactggtgtg ttgacaggta
     8341 aacctttgga tttttgggga agtaagatac gtacggaagc tactggttat ggattagtgt
     8401 attatgtcaa acatctattg aacgaagaaa aagattcatt taatcaaaaa acagtttttg
     8461 tttccggaag cgggaatgta gccatttatg caatcgaaaa agtgcaagag ctaggcggga
     8521 aagttgttac atgttcagat tctagcgggt acatctatga tccagaagga atagatgtga
     8581 aactattgaa agaagtcaaa gaaatcaata gacaacgttt gacggaatac gcaaaccaac
     8641 gtccttctgc tatttatcat gctggagaat ctgtttggac attgaaagaa aaagcggata
     8701 tcgctttgcc atgtgctact caaaatgaaa tagacgaaag cttggccgaa atcttagtag
     8761 aaaatgggat caaaatcgta gcagaaggcg ctaatatgcc atgtacagta aaagctgttt
     8821 ctgttcttca tgaagcaggc gtgtggtatt gtccaggaaa agctgctaat gctggaggag
     8881 tagcagtatc tgctttagaa atgagtcaga acgtccagcg attgacttgg gaaagagagc
     8941 aagtggatga gcagctggat caaatcatgg aaacgattta ccatacgtgt cgccaaacag
     9001 cagccgagta cggcgacgaa aaaaatctgc ttcttggagc aaatgttgct ggatttgaaa
     9061 aagttgccaa agcaatggca gcagaaggtt tagtttgaaa aatgaaactt tcttggaaat
     9121 attgtcagca ttttgtttat ttgcttgaaa aataataaaa aaaaacgtaa agtattacct
     9181 gtagagtaaa cctataagga ggagaacaaa tggcacacat tcattttgac tattcaaaag
     9241 tagcaccgtt tgtcaacgaa caagagttag ggtacatgca aagccaagta acagcagccc
     9301 acaacgaatt acgggaaggt actggcgcag gaagcgactt ccgcggctgg atcgatttac
     9361 caacgaacta tgacaaagaa gaatttgcac gtatcaaaga agcagctaaa aaaatccaat
     9421 ctgattctga agtattagtt gttatcggta tcggtggttc ttatttaggc gctcgtgcag
     9481 cgatcgactt cttgaatcac acattcttca atttattaga tagcaacaca agaaaagcac
     9541 cacaaatctt ctttgccgga aattcaatca gctcaacata tattgctgac ttgatcgaag
     9601 taatcggtga tcgcgacttt tcagtaaacg ttatttcaaa atctggaaca actactgaac
     9661 cagcgattgc gttccgtgta ttcaaagagc ttcttgttaa gaaatatgga caagaagaag
     9721 caaacaaacg tatctacgct acaacagata aagcaaaagg tgcagttaaa gtagaagcag
     9781 atgcagaagg ttgggaaact ttcgtgattc ctgatgacat cggcggacgt ttctctgtat
     9841 taactgctgt tggtttgtta ccaatcgctg ttagtggtgc agatatcgat gcattgatgc
     9901 aaggtgccgc tgatgcaagc aaagcatact caagcgacaa actagaagaa aacgaagctt
     9961 accaatacgc agcaatgcgc aacattcttt accgtaaagg caaagtaact gagttgttga
    10021 tcaactatga accaggaatg caatacttct cagaatggtg gaaacaattg tatggtgaat
    10081 ctgaaggaaa agaccaaaaa ggcatctatc cttcaagcgc aaacttctca actgatttgc
    10141 actctttagg acaattcatc caagaaggac gtcgcaatat ttttgaaaca gttgtgaagg
    10201 ttgaaaaacc tcgtaaatca atcacaattc ctgaacaagc agaagattta gacggtctag
    10261 gctacttgca aggaaaagaa gtggacttcg taaatacaaa agcatttgaa ggaacattgc
    10321 ttgctcatac agacggtgac gtgcctaact tgctagtcaa aattccagaa atggatgctt
    10381 atacattggg ttatacaatg tacttctttg aaattgctgt aggtatttca ggttacttga
    10441 atggaatcaa cccattcgac caaccaggtg tagaagctta caagaaaaac atgttcgcac
    10501 ttctaggcaa accaggcttt gaagatcttg ctaaagaatt gaacgaacgc ctgtaagata
    10561 agggtttttc gctagattta aataatcagt gatagaaaca tgttcgcttt aaaatgaaaa
    10621 ctggtaccca tttaggtact caaacatact gcatcgttta ttcagaataa ggggctgtga
    10681 caagacgttt gtcacagtcc cttgtttgta tagaaatcga ttgattgcct tgctctttag
    10741 tttgttttag gactttaaga acagtgaggc tgacttcgaa ggttaattct gtttttttgt
    10801 tttctagaat cagtaagcaa aaaagcactc acttcgagtg cttttttgcg atatattctt
    10861 agcttaagat aggcctaatt tttcttttac agatgagggt accttatcgc tggtaattac
    10921 ttttttctct atgatccgct tttcgcttgc tttcaactgc aagatcgttc cttcggggta
    10981 agcagaacca ttggcagagt caccagaagt aatgacatcg aaatctaact gtcttttttc
    11041 accgttttca gcataagcat ctacgttgta tttaaaacct cttccaatta cttccccatt
    11101 atctgctttg atatcagttt ctgcaggcat tggagctttg actaccgcat aataatcttt
    11161 acctacataa gtagactgat agtagtccca acctttccat cctataaaag caatcaatat
    11221 gataacgatc aaccctaaaa tttttttcat gaaagatctc cttttttatt tttat
//
LOCUS       DARPZF010000072        11255 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.075, whole genome shotgun sequence.
ACCESSION   DARPZF010000072 DARPZF010000000
VERSION     DARPZF010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.075"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="SLE65_002485"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="SLE65_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEI8449739.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="SLE65_002486"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="SLE65_002486"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEI8449740.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="SLE65_002487"
     CDS             complement(2169..2906)
                     /locus_tag="SLE65_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEI8449741.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="SLE65_002488"
     CDS             complement(2997..3524)
                     /locus_tag="SLE65_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449742.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="SLE65_002489"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="SLE65_002489"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HEI8449743.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="SLE65_002490"
     CDS             complement(4401..4886)
                     /locus_tag="SLE65_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HEI8449744.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="SLE65_002491"
     CDS             complement(5039..5236)
                     /locus_tag="SLE65_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449745.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="SLE65_002492"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="SLE65_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HEI8449746.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="SLE65_002493"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="SLE65_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HEI8449747.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="SLE65_002494"
     CDS             9211..9423
                     /locus_tag="SLE65_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEI8449748.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="SLE65_002495"
     CDS             9425..11104
                     /locus_tag="SLE65_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEI8449749.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3266 a         2429 c         1971 g         3589 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaata
//
LOCUS       DARPZF010000073         9316 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.076, whole genome shotgun sequence.
ACCESSION   DARPZF010000073 DARPZF010000000
VERSION     DARPZF010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9316
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.076"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..2122
                     /locus_tag="SLE65_002496"
     CDS             <1..2122
                     /locus_tag="SLE65_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449750.1"
                     /translation="KKINAVLSLFVCITILFFSTNVINGIKTSEALYKNTAEIHMQYK
                     DDMDFNSYINALYEISTQENINISQYSFTAVNQLTILATNPNANKHWKFSKKNILARN
                     DSKVHYTNNKNSKYQLKLPNNFLNINIYPFSHVENIGLSEILYVQGNSNKLIPVLKKY
                     GTPTISNINQSDTFQINTNIVLVICYLSIFIVITTIIFAFSKMKEITLKKMLGYNSFD
                     TIKDSIKELNLLFCSLIITFILSIFLSIYYSNENFFLSFLLCSIFHFIISFLFIIVTL
                     SIYHLSSIKNYLKNSRPLKLNLCILNICLFLSMILLLIASTKVINTHNEAENNSLKYW
                     ERTTNLYKTNITNQLNRNNTVEENNYLKKASKFVYKIQKNYKTFIIAPYNYATIQENN
                     KEFFIGQKVYPNFEDYVSQPAGAGICVDLNYLKYYNPISFEESTDLNLINSDPLTTYI
                     LVPKKYKEYAKMIEKNYLEDIQFRLEDSPPQAPYKNPNLKNLKIKLIFVNNNQKYFSF
                     NTLYGKAKDNYTITDPIVRVINPEITESLFWGNILTSDGGLFFDQKHTSNQNFFNQIN
                     PYIKEFNLENIINFSYSVFQETGELLSQKKVNKLNAYLQYLLILGLFIIINFQMIFVS
                     FTINSKKIALKKIFGYSPISQVLDLCLLPFTIELFATMCFQLIFSKNTYLYFIIFMIF
                     LINLITSIIIYKKNSFKYFKENIL"
     gene            2119..2739
                     /locus_tag="SLE65_002497"
     CDS             2119..2739
                     /locus_tag="SLE65_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8449751.1"
                     /translation="MILSVENFTLSINKKKIKQNWNFSISEKDFIIVTGKSGSGKTTL
                     LNNLSLIDKQYTGNLFYFEKKVSKHDIQRLRRNHISYLFQNYALLENQTVQYNFELAK
                     KFNSNISNDHIYNLLTDFSLPKDILKEKIFLLSGGEQQRIALIRNMLKPFDILFADEP
                     TGNLDKENSTFIMNFLKNLTEKEKKAVVLVTHDLNVLNYGTNIIEL"
     gene            2853..2990
                     /locus_tag="SLE65_002498"
     CDS             2853..2990
                     /locus_tag="SLE65_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449752.1"
                     /translation="MILLKKEYEKFYDRLIYSLQLPKKLNRQLQKTYETKSTEEWESY
                     C"
     gene            3432..3812
                     /locus_tag="SLE65_002499"
     CDS             3432..3812
                     /locus_tag="SLE65_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEI8449753.1"
                     /translation="MSEQNQNLASNSSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVASG
                     DAQRLSENLKIMQKELQKIWQQLR"
     gene            3794..4708
                     /locus_tag="SLE65_002500"
     CDS             3794..4708
                     /locus_tag="SLE65_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEI8449754.1"
                     /translation="MATIKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKK
                     KVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTP
                     EQPEIRPARRNHEQHVERGTDHQQELSL"
     gene            4948..5637
                     /locus_tag="SLE65_002501"
                     /pseudo
     CDS             4948..5637
                     /locus_tag="SLE65_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5757..5843)
                     /locus_tag="SLE65_002502"
     CDS             complement(5757..5843)
                     /locus_tag="SLE65_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEI8449755.1"
                     /translation="MFELFICPLLVGVCVSLFSYWLNNRNKK"
     gene            6488..7225
                     /locus_tag="SLE65_002503"
     CDS             6488..7225
                     /locus_tag="SLE65_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015060391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEI8449756.1"
                     /translation="MSNDIVRYNNGLNSVPLRKFTPIDMDLFWGICSKMKRKGTKEEI
                     FTFKQIKELIDYNINARGDRFANDLIKMSKKIITLSFIYEDEKTYEQLNLFQKFKIDK
                     VNETLLIKVSEEFEYILNSIGTNFTRFELENMTNLKSSYVKELYRQLMAHKDRRSKKG
                     HWFVKIEDFRALLAIPESYRMRDIDKQIFAQAKKEFLNVNSTHPAIFKTFEIKKIKAY
                     KGNKIGSLQIYFEENIPSITLDNWLEK"
     gene            7253..7792
                     /locus_tag="SLE65_002504"
     CDS             7253..7792
                     /locus_tag="SLE65_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEI8449757.1"
                     /translation="MQPKETFTIKELSELFEISRQAISKHVDKLDPSLLAKNERGYKV
                     VLRSGVLQLASNLGNQRLLYRLHEYEQENDKNVYISSKNVIVNELLDKLREENEFLRE
                     QLSLKEQNNSNMQKLLDQQQQLTLQANQQIEKLQEQLQLAYTEETPEDESTTILSEET
                     ESIEKHTKKKKQKWWQLWK"
     gene            7808..7978
                     /locus_tag="SLE65_002505"
     CDS             7808..7978
                     /locus_tag="SLE65_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449758.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
     gene            complement(8290..8751)
                     /locus_tag="SLE65_002506"
     CDS             complement(8290..8751)
                     /locus_tag="SLE65_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8449759.1"
                     /translation="MEDLGSKLRELRVKKGYTQEYVARKFNVTRQTISKWENNKTTPD
                     IETLKKICEFYSTNINSILNEDNSKNKKNNLLVLTAIIFNIFVTILGLFELIQMNFFS
                     FTHGIFTWFALSGLIVIDILNYFYIYYSYLKNEKFFYTMFFPLVILIILLS"
     gene            8884..9258
                     /locus_tag="SLE65_002507"
     CDS             8884..9258
                     /locus_tag="SLE65_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEI8449760.1"
                     /translation="MKKFLCLSALMGVLLTSGGIASATEALNLDVPEDHTAIYGGGME
                     ATEEGFSSSKLRYAAGGGDFNCGVNGFKVYANYYHARAKHSATAKNGRGGQVRSVQKA
                     GVRAYATCNATLTGNTGWWNVY"
BASE COUNT         3597 a         1413 c         1455 g         2851 t
ORIGIN      
        1 aaaaaaaata aacgctgttt tatcactttt tgtctgcatt acaatactat ttttttctac
       61 taatgttata aatggtataa agacttctga agcgctatat aaaaataccg ctgaaattca
      121 tatgcaatat aaagatgata tggactttaa cagttatata aacgctttgt atgaaatatc
      181 tacacaagaa aatattaata tttctcaata tagttttact gctgttaacc aactaactat
      241 tcttgctaca aaccctaacg ctaacaaaca ctggaaattt tctaaaaaaa atatattagc
      301 aagaaacgat tctaaagtcc attatactaa taacaaaaat tctaagtacc aattaaaact
      361 tccaaataat tttttaaata taaatattta tcctttttct catgtggaaa atattggatt
      421 aagtgaaata ttatatgtac aaggaaactc aaacaaatta attcctgtac tgaaaaaata
      481 tggaacacct actatttcca atatcaatca atcagatact tttcaaatta atactaatat
      541 tgttcttgtt atctgctatc ttagtatatt tattgtaatt actacaatta tatttgcttt
      601 ttcaaaaatg aaagaaatca ctctaaaaaa aatgttaggc tataactctt ttgatactat
      661 aaaagattct attaaagagt taaacctctt attttgttct ttgattataa ctttcatttt
      721 atctattttt ttgagcatat attacagtaa cgaaaatttt ttcctatcat ttcttctatg
      781 tagtattttt cattttataa ttagtttttt atttatcata gttactctaa gtatctatca
      841 tttatctagt ataaaaaatt atctaaaaaa ttcacgacca cttaagttaa atctttgtat
      901 attaaatatc tgtctattct taagcatgat ccttctgtta atagcttcta caaaagtaat
      961 aaatacccat aatgaagccg aaaataattc tcttaaatat tgggaaagaa ctactaattt
     1021 atacaaaaca aatattacta atcaattaaa tagaaacaac accgtagaag aaaataacta
     1081 cttgaaaaaa gctagtaaat ttgtttataa aatacagaag aattataaaa cttttattat
     1141 cgcgccatac aattacgcaa ctatccaaga gaataataaa gaatttttta ttggacaaaa
     1201 agtttatcca aattttgaag actatgttag tcaacctgct ggtgcaggaa tatgtgttga
     1261 tttaaactat ctaaaatatt acaatcctat ttcttttgaa gaatctactg acttaaattt
     1321 aataaactct gatccactaa ctacttacat tctagtacct aaaaaatata aagaatatgc
     1381 aaaaatgatt gaaaaaaatt atttagaaga catacagttt agacttgagg actctcctcc
     1441 tcaagctcct tataaaaatc ctaatttgaa aaatttaaaa ataaaactaa tatttgttaa
     1501 taataaccaa aagtatttta gttttaatac cttatatgga aaggcaaaag ataactatac
     1561 aataactgat cccatagtta gagttattaa tccagaaata acagaatcat tattttgggg
     1621 aaatatattg actagtgatg gtggattatt ttttgatcag aaacatactt caaaccaaaa
     1681 cttttttaat caaattaatc cgtatataaa agaatttaac ctagaaaata tcataaattt
     1741 ttcttattct gtttttcaag aaactggtga attattatct caaaaaaaag taaataaatt
     1801 aaatgcatat ctacaatatc ttttaatatt aggattattt ataataatta attttcaaat
     1861 gatttttgtt agttttacta taaattcaaa aaaaatagct ttaaaaaaaa tatttggata
     1921 ttcaccaata agtcaagttt tagatttatg tttactccct tttacaatag agttatttgc
     1981 tactatgtgt tttcaattga tattttcaaa aaacacttac ttgtatttta taatttttat
     2041 gatcttttta ataaatctaa ttacttctat tattatttat aaaaaaaata gttttaaata
     2101 ttttaaggag aatattttat gatattatca gttgagaatt tcaccctgtc aattaataaa
     2161 aaaaagatca aacaaaattg gaacttttca atatcagaaa aagattttat tatagtaaca
     2221 ggaaaaagtg gtagtggaaa aactactctg ttaaataatt taagcctaat agataaacaa
     2281 tataccggta acttattcta ttttgaaaag aaagtttcta aacatgatat acaacgtcta
     2341 cgaagaaatc atattagcta tttatttcaa aactatgctc ttcttgaaaa tcaaacagta
     2401 caatacaatt tcgaattagc aaaaaagttt aacagtaata tttccaatga tcatatttat
     2461 aatttattaa cagatttttc tttgccaaaa gatatcttaa aagaaaaaat ctttctctta
     2521 agcggtggag aacaacaaag aatagcatta attagaaata tgttaaaacc atttgatata
     2581 ttatttgcag atgaacctac aggaaattta gataaagaaa actcaacttt tataatgaac
     2641 tttctgaaaa atttaacaga aaaagaaaaa aaagccgttg tactagtaac acatgactta
     2701 aatgttctaa actatggaac taatattata gaattataat ttttacccgt gatgctagct
     2761 gatttaaaac tagcaccacg ggtatttatt ttatattcca tctctcctat cccaaaattt
     2821 aaataatcac ttaataaaaa ggaggcaccc aagtgatttt attgaaaaaa gagtatgaaa
     2881 aattttatga tagacttatt tattctttgc aattgccaaa aaaattaaac cgtcaattac
     2941 aaaagactta tgaaactaaa tcaactgaag aatgggagag ttattgctag atttttggta
     3001 gaagtaacaa aaagtggaca tattatcata atgactcgcc gaaagtctga taaaaaattg
     3061 gctaaaaata ttgctgaatg tttaataaaa ctatcagttt tagctaaata gttagtagtt
     3121 tacacaaaaa agcatttatg ttttttgttg caaagcaaca atttcatctt cggtgaaata
     3181 agcgaaactt tacaaaaagt ggctagcatt tgctagcttt ttttgtattg tggagcgtgg
     3241 cttttgaggg ggattcaagg gggagcttgc gcccctttga caagcggtta tttgcactaa
     3301 atacgtaggt atttggctag caaatataga gcttgccaaa cccttttagt gagctttact
     3361 cattgtacct ttttaggtac aatggtattg cgaacgatac gtccgtagga cgtactgaaa
     3421 gggtgggact tatgagcgaa caaaatcaaa atttggctag caattcttct aaaaaatata
     3481 cctatcgatc cgagccaaaa caaatcagtt ttcgagtgag cgaatccgaa tttgcaaagc
     3541 tgaagcaatc ggctgaagct ttgcaaatga gtgtgccggc tttcgtgaaa gccaaggcac
     3601 aaaacgcgcg tctggtgaca ccgaaagtgg cgccagacat tgcccaggca atcgcgcgcg
     3661 atttagccaa agctggaggg aatatcaatc aaattgctaa gtggtgcaat acacaccaac
     3721 atgacgttgc ttctggtgac gctcaacgtt tatccgaaaa cctaaaaatc atgcaaaagg
     3781 agctacaaaa gatatggcaa caattaaggt aagccgaacc acttcttgta gtcgtgcaat
     3841 taattacgca gaaccacgag caaccattaa aacaggaata aactgtgacg tcgattatgc
     3901 caaaagtgaa atgaaacaaa ttcgcatgct gtatggaaaa gacgaccgtg tacaggcaca
     3961 cttattgatt caatcttttc gaccaggaga aattaccgct gaaaaagcta atcaactagg
     4021 ggcagagtat gcaaaaaaaa tagcccccga tcaccaaata gctatttaca cacatacaga
     4081 caaagaccat attcataatc acattgtcat taactccgtt aatctggaga ctggaaaaaa
     4141 atttcaagct catggtcaag catttctaaa caaatgttat gacctaaatg acgagatttg
     4201 tcttgcacat aacttaccaa tcactgagcg aggaaagaaa ccagaaaaac gaaccatgtc
     4261 tgaaataaaa ttaaaagaaa aaaatgaacc tgtttggaaa gacgaaattc ggattgcgat
     4321 cgatcaaaca atgaaaaaca aaaaaaccag aacctatgac caattttgta attccctcaa
     4381 aacattgggg attcattgct tcaatcgcgg gaaaaatttc acttacgaat tgatccacaa
     4441 aaagaaaaaa gtacgatcca acagactagg aaaggactac gaaaaggaga cgattttaca
     4501 tgagctggac agacgagaac gaacctataa ccaacagcga accaacgagc tacgaagagc
     4561 tcgagctagc attcgcgaaa ctgcagaaga agtacgaaga gaacaacgaa ctcttacgcc
     4621 tgaacaaccg gaaattagac cggctcgaag aaaccatgaa caacacgttg aaagaggaac
     4681 agaccaccaa caagaattat cgctctaaaa cgttaaaaga catagaaaac gaaataaaga
     4741 aacaacgtgc ttttctcgtt ccttatacgc aagaaaggat acaaactacg attgatttac
     4801 aagttaaaaa actccatcaa gagctattag accagcgaaa taaggaacag aaaaaggtgc
     4861 ttattcaacg atcattggat tttcttgccc ccttatgttg cttagtcctg acactgttcg
     4921 cattttggtt agtatgggga ggctaaaatg gcattttatt taccctatct actcattttt
     4981 gttagtattt caggaagtat ttggctcatc tataaaattt tttaaacaag atattcatta
     5041 aaaggctcta aaattcgatt taagcgattt ttctttcttg gctgtatatt ttccttgata
     5101 atcgtttcaa gcggcttatt cggcgtttta gagggaaata agcgcgtttc tagaagaatt
     5161 ttattaggaa atgtcactca aaagtatgaa tcagcgcgtg ataaaaagaa aaaagagcaa
     5221 gcattagcac aaaaaatgga agagtttacc acttgttatg aggaaatgaa cgatattttt
     5281 gtgaatcaag aaaaacgttt gacggataaa aacatggaaa aactcactcg tctttatcaa
     5341 aacttgccag aaaaacagca aaaagaggtt caagacaact atgagcgaac caaaaaagac
     5401 gtgcaatatg taaaagatac aaagatagaa gaagcctgta gtgatctatt tggagacaca
     5461 aacccttggt ttgccagtga agaagaaaaa aaagaaaaac aacaatctgt cacatatgaa
     5521 cgctatgaaa tcttacttca acaagcaact aacatgcaaa atccgacaaa aaaagaaacc
     5581 gccttaaact atctaaaaag tgtcaaggaa tggttagatc agcaacaaca aaattgaatt
     5641 tgatttaaaa tcatgttaaa ctgaatgtgc aaatgatcaa acattagata cacgaaagcc
     5701 ccagagaggt cggattctct ggggcttttt tcaggttgat gtcgccttta ttgattttac
     5761 ttcttgtttc ggttattcaa ccaataactg aataaagaga cacaaactcc tacaagaagg
     5821 gggcaaatga acagttcaaa cattagatac acctccttcc agtcgcaaga ctgtcggata
     5881 ggcgacaagt tattatatct taaaaaatta aatttgtgtg gtgtttttaa gtatcacttg
     5941 ttttagggtt gttagggctt gccctgaccg cctgtaaggc gcttctcgac tagattaagg
     6001 gaaattaatc aagaattgtc ttagaacggc ttagacaagc tttcagagtc tcacacctcc
     6061 tctttgaaca acggttttag caaaggagcc ggaggcgact gcgcagtata atatgagagc
     6121 atagcgatca caccttttta gcgaccgtag ggagcaagtt ttccagttta gaaaaattcg
     6181 cgaacctttt tggaggaaaa agtaggagtt ttttaggcgg gaaattcaat gtgctcttaa
     6241 gatatactgt tagatatact gttagatata ctgttaataa taactgttag ggattagcaa
     6301 ccttatggga gagtaagtat tgacataggt agtgggggat aaattgtcac actatggggg
     6361 ataaattgtc acactatggg ggataaattg tcacactatg ggggataaat tgtcacacta
     6421 tgggggataa attgtgtttt acatcctctt atgtctatga taacataatt tattgaggtg
     6481 atttttattg agtaacgata tagttcgata taataatgga ttaaattctg tccctttaag
     6541 aaaatttacc cctatagata tggatttatt ttggggaata tgttctaaaa tgaaaagaaa
     6601 aggtacaaaa gaagaaattt ttacatttaa acaaataaaa gaattaattg attacaatat
     6661 aaatgcacgt ggcgaccgtt ttgctaatga tttaataaaa atgtcaaaaa aaatcattac
     6721 tttgtctttt atttatgaag acgaaaaaac atatgaacaa ttaaatctgt ttcaaaaatt
     6781 taaaatcgat aaagtgaatg aaacattatt aataaaggtt tctgaagaat ttgaatatat
     6841 acttaattca atcggaacta attttactcg tttcgaatta gaaaatatga caaacttaaa
     6901 gagtagctac gttaaagagt tatatcgcca acttatggct cataaagaca gaagatctaa
     6961 aaaaggtcac tggtttgtaa aaatagaaga ttttagagct ctattagcaa taccagaaag
     7021 ttatcgcatg agagatattg ataaacaaat ttttgcccaa gcgaaaaaag aatttttaaa
     7081 cgttaattca actcaccctg ctatttttaa aacttttgaa atcaaaaaaa ttaaagccta
     7141 caaaggaaat aagataggat ctctgcaaat ttattttgaa gaaaatatac cttcaattac
     7201 cttagataat tggttagaga aataatacct aacaatttag gaggcaatta tcatgcaacc
     7261 caaagaaacc tttacaataa aggaattatc tgaattattt gaaataagta ggcaagcaat
     7321 ctctaaacat gttgataaat tagacccgtc cttattagct aaaaatgagc gtggttataa
     7381 ggttgtatta cgttctggag tattgcaact tgctagcaac ttaggtaacc aaaggttact
     7441 atataggttg catgagtatg aacaagaaaa cgataaaaac gtttatatat caagcaaaaa
     7501 cgtgattgta aacgagttgc tagataagtt gcgtgaagaa aatgaatttt tacgagaaca
     7561 actttccctc aaagagcaaa ataattctaa tatgcaaaaa ttactcgacc agcaacaaca
     7621 gctcacccta caggcaaatc aacagatcga aaaactgcaa gaacagttac aattagctta
     7681 tacggaagaa actccagaag atgaatcaac tactattctt tctgaagaaa cagaatcgat
     7741 agaaaaacac acaaaaaaga agaagcaaaa atggtggcaa ctttggaaat aactggaggg
     7801 aacattcatg acaagaaaaa atcttctatt cggttctatt ttactaggaa ttctaggctt
     7861 cagtccgatg ttattgtcag taatcaataa agggaataaa catggtgaat tgaaattgaa
     7921 tccaaattat tacaacagtc ctaacgaaga attgtttgta aaagagacgg ataaataata
     7981 aaaaagactg ctcttccgag cagccagtta aaaaataatg agtgtttatt cttgaaaaag
     8041 cacgcgctta tgaagcgcta ccaaaaattt accatatttt acaaaaaata acaagtctta
     8101 aaaaaatgac agataaaaat gcacaaagaa ttagatatag ataaccgcga aaaatcaagc
     8161 tttagaaagt tgcttttagc tagaccaatt aaaaatcaca aagtgagcgt ctctatccat
     8221 tggtagaggg gctacttggc atagtgtaca ttatgtcaac tatgcaatta aataactaac
     8281 tacttcatat tagcttaata aaataatcaa aataactagg gggaaaaaca ttgtataaaa
     8341 aaatttttca ttttttaaat aagaatagta aatataaaaa taatttaaga tatctattac
     8401 tattaatcca gatagagcaa accaagtaaa tattccatgt gtaaagctaa aaaaattcat
     8461 ttgaatcaat tcaaataaac ctaatatagt aacaaatata ttaaaaataa tagctgtcaa
     8521 taccagtaaa ttattttttt tattttttga attatcttca tttaaaatag aatttatgtt
     8581 agtactataa aattcacaaa ttttttttag tgtctctata tctggtgttg ttttgttatt
     8641 ttcccacttt gaaatagttt gacgtgtaac gttaaatttt cttgccacat attcttgagt
     8701 ataccctttt ttcactctta attctcttag cttagatcct aaatcctcca ttttttctcc
     8761 tatgtaaacg attatttaca taaaatttta tcataaaaat actaacgcgc caaaaaagtt
     8821 ctttatttta taaaacacac taaaataaaa taattctagt aaaaaagata ggagaaataa
     8881 gttatgaaaa aatttttatg tctttctgct ttaatgggtg tcttattaac tagtggagga
     8941 atagctagtg ccacagaagc tttaaatcta gatgtacccg aagaccatac cgccatttac
     9001 ggaggaggaa tggaagctac agaagaagga ttttcttcta gtaaattgag atatgctgct
     9061 ggcggcgggg atttcaactg tggggttaat ggatttaaag tttatgcaaa ttactaccat
     9121 gctagagcta aacatagtgc aacagctaaa aatggacgag gcggtcaagt acgatcagtt
     9181 cagaaagctg gagtaagagc ttatgcaaca tgcaatgcca cacttactgg aaatactggt
     9241 tggtggaatg tttattaaaa aagagagttt aaactctctt ttttatttac atttgaaagg
     9301 aaattcaaaa tatgtt
//
LOCUS       DARPZF010000074         9210 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.077, whole genome shotgun sequence.
ACCESSION   DARPZF010000074 DARPZF010000000
VERSION     DARPZF010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9210
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.077"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            471..2108
                     /locus_tag="SLE65_002508"
     CDS             471..2108
                     /locus_tag="SLE65_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449761.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(2253..2993)
                     /gene="truA"
                     /locus_tag="SLE65_002509"
     CDS             complement(2253..2993)
                     /gene="truA"
                     /locus_tag="SLE65_002509"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEI8449762.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(3184..3819)
                     /locus_tag="SLE65_002510"
     CDS             complement(3184..3819)
                     /locus_tag="SLE65_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HEI8449763.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3966..5207)
                     /gene="sstT"
                     /locus_tag="SLE65_002511"
     CDS             complement(3966..5207)
                     /gene="sstT"
                     /locus_tag="SLE65_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEI8449764.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            5405..6401
                     /locus_tag="SLE65_002512"
                     /pseudo
     CDS             5405..6401
                     /locus_tag="SLE65_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
     gene            6417..8435
                     /locus_tag="SLE65_002513"
     CDS             6417..8435
                     /locus_tag="SLE65_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HEI8449765.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(8495..9187)
                     /locus_tag="SLE65_002514"
     CDS             complement(8495..9187)
                     /locus_tag="SLE65_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HEI8449766.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT         2979 a         1706 c         1445 g         3080 t
ORIGIN      
        1 aactaatcag aatcgtacaa atatttaata accaaatata tagaacataa cttaatatta
       61 agttatttga aattccataa aaaacgactg caggaattat tgtaagaaaa ggataaaaat
      121 agttcagtcc atctccataa ttgttaaatg ttgtatagtt gattggccct tcaaaaatag
      181 aagataaccc tttgattcgt gaaagatgaa aagataaatc acctgttgta taaatttctt
      241 gagcatttct cataaaattt actgaatata aagtactaag taagataaga actactaaaa
      301 gaaatgcttt tttacttatt ttcatagatt tgttgttctc cttttttaat tctattttca
      361 gtatactaga attgtctttt tttaataagt tttgcgttaa atttttcata gcactagtat
      421 gatatactag aaaagaatca atttttatta cttttaaata ggagaaaaaa atgaaaaaaa
      481 acaaaaacca aataatagat atcattttta tgttatttct aagttttgct tacgtcatcc
      541 ctctattcat gtctatggga atctatcata gtgtcaatca ggatacttac tttcatttat
      601 ctcgaatcat aggactagat aatgtatgga gttctccagt aaacttcaat aacttcgatc
      661 atcatggaac aatgatgaat attttttatc catggcttac tctttatcca gcttttttat
      721 tttataaaat gatgggaaat cttgttttaa gttataatat ctactatttt tttatcactt
      781 ttttaacaat ggtcgtttct tatttttcta tgaaacaaat aaaaaacaat cgttatattt
      841 cgctgttatt ttcgattatt tatacatttt ccgcctatcg tgccattgac atattccatc
      901 gtgcttcatt gggagaagct gtcgctttaa catttttgcc tttgatacta atggggtgtt
      961 acgaaattta tattagagat taccaaaaat ggtactggtt gtctattggc atgacgctag
     1021 tagtgtatac tcatttactt tctgtcgcta tggtttctgt atttattgga ggaacgttgt
     1081 ttctttcttt ttatttttgg gaccaaaaaa tcgctagact cttaagtctt ttaaaagcta
     1141 ccgtcctcac ctttttttta agtgcgggat tcttaattcc ttttattcaa caatctagag
     1201 cacaagaatt gaaagtccca ctgggaaaag aattaagtgg tatggctcct agtgatatgc
     1261 tgacacacat tttaaataat aactataaca actatactat tggattattc ttatttctcg
     1321 gattgattgg tgcttttatt tttataaaaa aattaactgc tgatgattta tttattttct
     1381 ttcttggtgt atttgttctt ttttgttcaa ccaatttatt tccttggcaa ctttttaacc
     1441 atacaccagt taagagtcta caatttgtct ggcggttaaa tggtttttct tctttattta
     1501 tagcctatac gatgagtata gtgatctatt atattttttc tactaaaaat aattcatgga
     1561 aaataatggt ctttacgttt cttgcactaa tattgcatct ctcaggagta agcaattcta
     1621 tccatgctaa caaagattca ttaacactta tagcacctga agacgctgtt gctatagctg
     1681 aaaattacaa tcatactgat tatgcaaaca aagagtcaat ctatcatcct gatatgatta
     1741 ataatgatca atatttacta ggtaaccagg aaataaatcc aacaactcat tttatgagta
     1801 acaaacttac aattgaatta gataattcga ataataaaaa tactgtcttg acgacaccta
     1861 tttatcgtta taaagggcaa gtggcttcta ttaatggcaa actagtacaa acaaaattat
     1921 ctaagtttgg cacaactgaa ttaactattc ctccaggtat aaataaagtc gttattactt
     1981 atcagtacac aaaactagca attgcttcaa gatatttatc tatcgttact ttgattttat
     2041 ttttacttta tcgatttact ttttctaaac aaaaacaacc gagaagagaa gtacaacatt
     2101 ctcactagat ttttatttaa gaaagacttt ttagctgtac acataaacag gctaaaaagt
     2161 ctttttttat atttctttaa tttgcttcat acattattta acatcgatat ttatactgtg
     2221 aaacatgcgt ttcatccatt atcaaagtat ttttatcgat aataaacttc atccaaaaac
     2281 agaccttgtg cagggacggt ttctcctgca tgttgccgca ctttgctttc aaatatttca
     2341 tcgattgttt ctatcggcat ggcacctgtg ccgatttcta gtaatgtccc catgataatc
     2401 cgcaccattt tatataagaa tccgtctccg acaaaagtaa aatgaagcat ttctcccttt
     2461 cgttcgatag ataattcatc aatcgtacgc actgtggatt tttttgattt tttcaatgca
     2521 gaaaaaccaa tgaaatcatg tgtacccact aatttttcgc aagctgcatt cagcttgtcc
     2581 atatccaact cttgagggaa ataaaagctg tggtttcgct caaatgctga aggaatcacg
     2641 ttgttccaaa cataatagct gtattttttg cccaccgcat tatatcttga atggaagcgc
     2701 tcaggcattt cttcgattct tttgatgaca atatcccgcg gaaggtaacg attcataaag
     2761 tcgatcattt ctgccagtcc aatttctgtg tttgttttaa aatttgctac ttgtcctcgc
     2821 gcatgggtgc cagcatctgt tcttcctgat ccaataattt ctatctcttc atttgtcatc
     2881 tgatgcaata ctttttcgat ttttccttga atggttttat cgtcatctcc aagtctttgc
     2941 catcctgaat atctttttcc gtcatattcg attgtcaact tgatgtttct catattttag
     3001 tggctcctct gtcttccatt tggtcttctc tctacctttt taagattgta gcacaaaata
     3061 tagctccttt cttctctaaa acagaagcta tacaagaaaa ctgtggaaat atatatttca
     3121 gaaaaacaaa aaacagccac cggatgaagt atccgctgac tgttcaattt gacggctcaa
     3181 gttttactgt ttgagatgca agatactcaa ccaggcaatg ggcacataat taaagaaaaa
     3241 actgattctt tggcaaaaac ctattttatt cagtaatggc caagaattta tagaaggaat
     3301 tcttgccagt ccataaatcg ccgcaaaaag caaactgatc acagacagtc caaggtataa
     3361 gtggcttacg tccatttgcc cattttttcg atagatcaag aaaagaagaa ctggaaacaa
     3421 taaaaaacca ctgtaaccta aacctgatcc gatattatgg acccatgtcg agacattcca
     3481 cgaagattca tgggtattga tactgaacaa acctgtaaag atacaatcac ctataccata
     3541 gaacgcgatg gctgctgtaa ctagggtagc taacacacga gatgtactta caaatgcagc
     3601 atacaatgca ggcaatgaca ggatgaaaaa gatccctgaa accacagacc aaataagaaa
     3661 cgcttttctt acaggactgg aaacctctcc aaatacactg atcacgctct tcatttgatc
     3721 taattcagga taatacaatc ctaatacgta cggagtcaaa aaatcactca gcacgcctaa
     3781 taataaaaag aaaaaaccaa atttacgtaa aaaatccatg atacgcctcc aataacaatt
     3841 acctatgctt ttaattgtta ttataaacga ctttatcttg atttaacaga aacctctatt
     3901 tacacgaaca tctatataac tcattaaaaa ctcgaatcat tttaaaaata ctaaatatct
     3961 aacgttcaac gttcacttaa tccatctaaa caatctttca atttgatttt ttccccactt
     4021 cttttacgcg cgcctagctc tcctattgca gtaaacaaca gatcacttga cgaatttaag
     4081 gcagtttcca ttgaatcctg gataacaccg ataataaatc caataccgac gatttgcatc
     4141 gcgacatcat tagagatacc aaacaaacta catgctaatg gaatcaataa cagtgaaccg
     4201 cccgcaacac ctgaagctcc acaagcagct aaagcagaca aaatacataa aaggactttc
     4261 aaaacaaaag gtgcttcaat ccctaaagaa tgtacagcag tcaacgtcat caaggaaatg
     4321 gtaatcgcgg caccgcccat attgatcgta gcacctaacg ggatcgatat ggaataagac
     4381 tcttttgtca atttcaatct ttcagccaac atcatgttta tcgggatatt tgcggcagaa
     4441 cttcgggtaa agaaagcggg aagtgcgctt tctttcaaac aaaagaaaat caatggatag
     4501 ggattttctt taataaacaa aaacgtgagg aatgggtaca caactaatgc gacaaacagc
     4561 atcgtaccga tcaaaacaag taaaagctgc agatactctg ccaatccagc gattccagtc
     4621 gtagcaattg attgataaac caatcctaaa atccctatcg gagcaaatgc aataatcact
     4681 tgtacgactt gtgacaacgc tatagatatc tgatccacca actcttttgt cgattctgaa
     4741 cgtgctcgaa aagctagtcc caacaataca gcccagaata agacgccaag gtaattcgca
     4801 tcaataagag attgaacagg attttgtgtg acattcgtca acatagtaga taaaacactt
     4861 tccaaacttt gcggtgcttt ttcagatact gtttcttgta aagtaatagg aacagtaaaa
     4921 attgaactta caataactgc tacaagtgca gaaagcaatg ttcccactaa atataagatc
     4981 aaaataggct tcacgaatgt cttattccca attttatgct tggcaattga cgccatcgtc
     5041 aagaaaaaaa ccagaatagg tgcgattgcc ttcaagcaac tgacaaacaa cgttcccaat
     5101 attgaaataa atgtccatgt ggggaaaaag ataccaaaca atattccgac taaaatacca
     5161 acaacaatac gttgaactaa cgacatatcc aaaaacttct ctaacaaatg accacccttt
     5221 cacaatttta acaatcattg tatcatttta tgcaaagaaa ctaaaggtat aattttctaa
     5281 aaattctaac aatacaaaca accatttctt gctaattttg tactttttct gtctacacgt
     5341 tgttttttga gatattctaa gttaggatgt tattaatggg caacttatca ggaaacgttt
     5401 tcttatgttt ttgtccaatt tttttgtgag gtgtttattc ttgaaaaaaa taaagaagga
     5461 gagttatggc ttcctgacaa tctttgtcgc ttgtataatg atggttttac agcgtatatt
     5521 gatttcagca gtcactattc ctacatatgc aacaaaccct ggtcgattct acatctatac
     5581 atttttacaa acttccgttg ttattggtgc aaatttgatc ccactttaca tgggttacca
     5641 atatcaaaaa atcgcccgtt taaaagtttt acattattta agtcgttttg cctttatatt
     5701 cctaatagcc acactagttt gcaatatctt ttttttacgt acaagctggc agcttgaata
     5761 ttcgtgatta ttggcttatc ctaacaccta tcagtcagaa ttactttact tatgctgttt
     5821 cttgtacttt gcttttttgt agtattcctt atacagttgg atttttaaat aaattatcga
     5881 aaacaacaat taaatatcta ctattatttt taacaattgg attagttggc tgctctactc
     5941 tatttaataa agacccgttt gcattacaga atggacagag tattttatgg attttttatt
     6001 tatttttaat gggttatggt ttgaaagaat ggaactggaa agaaaaggtc cgctataagc
     6061 ttcctcaagt atttatcagc ttgattgttt tattcggttt gattattttg atgacacaaa
     6121 tttcactcat catcagagga aatacagata cagcgctgag gttttctaaa ccatattctc
     6181 tcttcgcaat gtattatact ttctcttcgt ttttattttt agaaatgcta tctgataaat
     6241 taggtataaa aggaagagga aattttcttg ctgtattttt gattgtcact caagttatat
     6301 gtaatttccc tttagtttct tatcgcgtat ctacatttat gaaacgtgaa tttccaaact
     6361 cagggaaggc atggctgata aatatcgggc agttttttat ttgctattta ttagcagtgt
     6421 ccctcctagt tatcttttta ttttatatac aaaaaatccg tttcattcat cgtttcatcg
     6481 aatacttcgc ttttgattcg attgaacaat taactcagcg ttggaaaaaa agaattcatt
     6541 ggctttttgt tcataaaagt tattttttag ttgcagcatt tttttactgc tttaccttcg
     6601 tgcagatttt cgttttagaa ccaaaagaag gttggaaaga aactatccag gttgccttaa
     6661 aaatatttac tcagcgacaa gcacccatga tcctgacaat catcattatt atgggatttt
     6721 tcttcttact attgttgatt tccaatcgtt tttggtacgc cttgactgct accttgatca
     6781 ttaacttact gctcactatt tcgacagtaa tcaaaatgga aatgcgggaa gagcctgtct
     6841 ttccttcaga tttaaaaatg ctgaccggat tgtcagaact attatcgatg gttagcccag
     6901 tcttattaat cgtgggcgga ttgatccttc tcctattatt gattactagt attattgtac
     6961 aacgtagact acaaaaacag tattccttga agattcattg gaaacgtcga tttatcagta
     7021 tcgctgtatt attaggatgt ttttcgggtg tctttttcat taatcacaaa aattcgcctt
     7081 ctttcttgct gtttaattta tttaaagtaa acaagacttt ctttaaccag caaggcgccg
     7141 taaaagataa cggaccagtc attcaattcc taaacaatat cgacattaaa atcatggaag
     7201 aacctgctgg ctattcgaaa gaaaaaatta atggaataat gaaaaagtac aacacaaagg
     7261 cagatgaaat caaccaaaca agaagtgact ggttaaacaa tcagacgatc gttctcaatt
     7321 taagtgaaag cttcagtgat cctgcacgtg tccctaatct gacagtacct acagacccta
     7381 ttccttacat caaaagcatt ataacagaag gaacaggagg attgatgtta tccgtcggtt
     7441 atggtggcgg aacagctaac atggaatggg aaggactgac aggcttgagt atcagtaacc
     7501 tgtctgcttc gttagttaca ccttataccc agctagtgga gcgtcagaaa ataagtccaa
     7561 atattaccga tctattcgat gaaaaaatag ccatccatcc ttttacagct gctctttatc
     7621 gcagaaaaca agtgtttgat aaatttggtt ttgacaggtt ctattattta gacagtccgg
     7681 ataaattaac ttatacggat aaaatagaac aaagcccacg catatcggat gattcagcat
     7741 acaaagaaac cttgaaagct ttacaaagca atacagaaac gtcacaattc atccaattat
     7801 ccactatgca aaaccatatg ccttatgatg attactatag tgaattgaac tacactgctg
     7861 aaggaactgc tgtcattcct aatagaagaa aagaattaca aacttatatg caaggccttc
     7921 actataccga tacagcagta aaaaaattca tccaagaaat cgacaaaatc gataaaccga
     7981 ttacctttgt tttttatggt gaccatttac ccgcaatcta tagtgggaat gattcgaaaa
     8041 aatatggatt agaacagcac cagacagatt atttcattta taacaacaag tatagtcgtg
     8101 aacaagcagc tacgttaaat aaagaagttg ttgctcctaa taactttggt gctatggctc
     8161 ttgagcatgc gaatatcaaa gtaactcctt actatgcgtt gttgacagaa gtatctaatc
     8221 atctacctgc attaacaatt gatcctacag aaagcttgtc taatcgtttt aatggaaaac
     8281 aggtctttgt tacagaggat agtcaaatta tccaagaaaa aaatttaact gagaaacaaa
     8341 aagaaattct agaagattat cgtctgatac aatatgatct tgttgcaggt aaccagtaca
     8401 gtgcaacatg ggcgacacaa aaaataaaag actaacaaat aaactgagca aggggttgtg
     8461 ataaaagaca tgtcacaacc ccttgtttat ctcattaatt tgcttgtcca taaacgattt
     8521 gattaaagcc atttttcaat tcattattcg ctgtctcgtt gaagtaaaga taattatcgg
     8581 gattcccctg attttgttgt gtcaccaata cttttggctg attttgctga aacccgaata
     8641 gatagacgtg ctttttcaga tatggttctg tctctgcatc ggaatagacg gctgtgattt
     8701 gatagtctgc ttgacctgtc ccactttctg accattctgc agaaacaggc actccaccaa
     8761 tagccatctt ccactccccg ttcaaaatag cttgagggac tttaagacca tataagtcca
     8821 cactcatttg attcgtataa cttttgtatt gttgtcccat tgtttggccc catttggtca
     8881 taaatgcctc taattgtgcg gatttgtctg cattccacag tgtttgttca acttgttcgc
     8941 tgctttctga agaggaagat gaagcctcta cagaagaact tgaagtagat gtttgagttg
     9001 tttcagtcgt tttggaagac tctgacgaag tagaggtatc tgctgtttct gtacttgctg
     9061 cagttgactt gctctctgtg ctagttgttg tagtagttgc aactgttgct ttcgctgttt
     9121 cttttgttga ttcttttttc gattcattcc cgttggtaca accagctaac aaaaaagcta
     9181 gaccaattgt tactaaaatc ctttttttca
//
LOCUS       DARPZF010000075         8969 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.078, whole genome shotgun sequence.
ACCESSION   DARPZF010000075 DARPZF010000000
VERSION     DARPZF010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.078"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(57..350)
                     /locus_tag="SLE65_002515"
     CDS             complement(57..350)
                     /locus_tag="SLE65_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HEI8449767.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(378..1043)
                     /locus_tag="SLE65_002516"
     CDS             complement(378..1043)
                     /locus_tag="SLE65_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEI8449768.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1183..1815)
                     /locus_tag="SLE65_002517"
     CDS             complement(1183..1815)
                     /locus_tag="SLE65_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8449769.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1822..2889)
                     /locus_tag="SLE65_002518"
     CDS             complement(1822..2889)
                     /locus_tag="SLE65_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEI8449770.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(2886..3617)
                     /locus_tag="SLE65_002519"
     CDS             complement(2886..3617)
                     /locus_tag="SLE65_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEI8449771.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(3786..4265)
                     /gene="greA"
                     /locus_tag="SLE65_002520"
     CDS             complement(3786..4265)
                     /gene="greA"
                     /locus_tag="SLE65_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEI8449772.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4401..5576)
                     /gene="mltG"
                     /locus_tag="SLE65_002521"
     CDS             complement(4401..5576)
                     /gene="mltG"
                     /locus_tag="SLE65_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEI8449773.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            5780..6949
                     /locus_tag="SLE65_002522"
     CDS             5780..6949
                     /locus_tag="SLE65_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEI8449774.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(7216..8850)
                     /locus_tag="SLE65_002523"
     CDS             complement(7216..8850)
                     /locus_tag="SLE65_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449775.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTLKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT         2856 a         1701 c         1333 g         3079 t
ORIGIN      
        1 aatattttca aaagaaaaaa gagaaggtga caaaaattgt gtcaccctct ctttttttat
       61 tgttttttaa agtgataggt tggctcctcc aggttgggat cataatcaac aagtaaatca
      121 tatcctttaa agaaccattc atctgcttcc tcgataaaaa aaagtgtccc atcaatttcc
      181 actttcttta caggatgttc tggctgttca actgacattc caatcgaaaa accatcatga
      241 acctctgttt tgccgtagac ttttccaaaa aaacgtattc cgtaagtttc tggcagatca
      301 atttctgagt caaaccactt ttgtgctttt ggcgttaccg ttaatttcat cccaacaacc
      361 tactttctct tttctttcta ttgattcatc ttatcgtcta gaatatccac atcgcctgtc
      421 tctccaataa ccagtagatt atcattttca cgaacatatt catctgctgc aggagaagcg
      481 ataaccgttt gatctactct tcgtatggcg actactgtta agtcaaaacg ttgcctgaaa
      541 tttaattcag ctaatgtttt gttgaaaaat ttaggattgg agactcggat ttctgctaaa
      601 gaatatttat ctgacaactc taggtaatct aaaatattct ttgacactaa attatgcgca
      661 atccttattc ccatgtctcg ctcgggatgg acgacgcgat cagctccgat cttttcaagt
      721 actctggcat gatactcatt ttgggctttt gctaaaatat ttggtacgcc catttccttt
      781 accatcagag taactaagat actggcttga atatcttctc caatagcgac aattacatga
      841 tcgaaatttc ttatgcctaa tgatcgaagt gtcatttcat cctgtgcatt tgccacaaca
      901 gcatgagtgg ctatattcat atattcattg acccgatctt cattactatc aatagccagt
      961 acttcttgac cagcttcgat cagtgttcgg cagatacttc cgccaaatcg tccaagacct
     1021 acaattgcaa aattttgttt caccgttttc ctcctttagt atcttctttt ctcagtataa
     1081 caaagccttt acaaaaacaa aagcaagcat cattattgta aaaaagccaa gaaaaataat
     1141 agttattttc tcagcttttg attatcctct ttatcatcgt ttttatttca ccaaaccatg
     1201 tttgaatgca tagatagcgg cttgtgtacg gtcttccact tctagcttag ccaatatatt
     1261 ggaaacatgt gtttttactg ttttcagtgt aataaacaat tcgtccgcta tttcctgatt
     1321 actttttcct tcagaaatca gcattaaaat ttcattttcc cgattcgtta gttcttcatg
     1381 taatacaggc tcatttcgcc gactcatttt ttccatcatt tttgttgtca cttctggttc
     1441 taatactcgc tcgccacgtt gcgttgccct tatagcatca gcaatttcat gtgcggtaga
     1501 ggtcttcaac aaataccctg ctgcacctgc ttcaatggca ggataaactt tttcgtcatc
     1561 aataaaactg gttacgataa tgattttagc ttctggccaa tcttttaaga ttgcttttgt
     1621 tgattcgata ccatccattt cttccatgac taagtccatt aaaatgacgt ccggtcgaag
     1681 tgtcatcgcc ttctcatagc cttgtcgtcc attttcagct tctccaatta cttcaatgtc
     1741 ttcttgaata gataaataag aagagacgcc taagcgcacc atttcatggt catctactaa
     1801 taaaactttt atcatcctta tctatgcctc cttcatcaaa gggaccttga tttctacact
     1861 tgtaccttga cctttaaaac taatgatttt tactgttcca ccaataccag ctactcgttc
     1921 tttgatattg ttcaatccat aacttcccgt tttcgtttca ttcatattaa accctgttcc
     1981 gtcgtcaata atacgtaaca aaagattatt gtctattttg tgcaaatata cctctaattc
     2041 attggcttta gcatgtctta atgtatttga taacaattct tgaacgattc ggaacaagtg
     2101 atcctcaatg gaactagata gttttacatc ttctacatcc catttcagcg aaatctggat
     2161 tttattttgc aattccttca ataactgctc gataccttgc tttaaacttt tctcttctaa
     2221 attgactgga cgtagatgaa gaagcagcgc acgcatctca gactgggaag cgttgatgat
     2281 ctctgctacc attttcaact gcttgcgaaa catttctggt gtctcgcttt tttctgcttg
     2341 ctccgtcaat gccgacatca tcatcattgc tgcaaacaat tgttgcgaaa ctgaatcatg
     2401 cagctcacgg gctaatcgat gtctttctaa ttctaaaatt tcttctttgg tttgtccatc
     2461 tacatattgg ggacggctcg ttacaatttg taattcacta gatacttcaa tcattttttc
     2521 ttttatctta gtgatttcct tatcaatatc tttgatgtat aaatcgtccg atgcacttgg
     2581 gatcggaaga agcaacaatt tggattcata attgccagaa gaaagtgcac gcagcttttc
     2641 ttcgattttc ccgtattttg tcttttgaat aagtgataat aatagaaaga caattaatcc
     2701 tacacctaag gaaatggcta acaaatggaa gataagcgga acatataata aacgtgcacg
     2761 cagtaattct ccccaccaat gactttgatt gctggcataa aaataagtga aaagtgaaaa
     2821 tagaataata aggaaagccg caatccccga ataaacagct agcatcgctc tggatatttt
     2881 tcccatcata ttcgtatcac ctcgacatct ccaatcaagg tattagtaat aatcttcaat
     2941 ctacgagggt tttcatcata atcactgctg tagattttga tttgttcatt tttcaaagaa
     3001 aattgctctt cttcaaacaa gacatttcct actaatgtcg catgctctaa tcggatggct
     3061 acgcccaaag gtactaagat ccgtgttctg cctatccctt ttcttacaat cacaatatta
     3121 tcatcttttg gcaaaagcgt attgcccaaa tctatgatag tatcaccaga aatgacggcg
     3181 atgttgatat cgtcccattc atagacgtcg tttccaatac gttggttacc gaataattgc
     3241 tgtcttttcc gctcattatt atgtgttttt aattgctctg tttggatcat catgatctgt
     3301 ttctttcgcc aaaaagcatt tttggttaaa tctatccctg aaatctctac acctttcaga
     3361 ccaataaata aaacggcaaa tacagccatc atccataaag caggactgtt gactaagcta
     3421 aaaaaaatga ccaaacttcc taatatcaat tgaaaatttt gaaatttagt acgaggatgt
     3481 ttgcgcatag ctagatatat attgaaaata ccgaatatca ctaaaagcaa aagtccagta
     3541 ttgtttacga tttgccaaac agcaaataac agcagtagtg cttcaactac cacaaaaaaa
     3601 cgccaagaac tattcatcgc tctttctccc tcctgacaca ttctcatttc atcataccta
     3661 tttttttaac tgttggctat aggactttag atgtaagatc gtttgttgaa atctaaaata
     3721 cacaaagaga aaaagatcta gagtgtatca tcagtaagat gaactctcta gatctttcag
     3781 tcagactacg cttgttctac tttgacgatt ttaactaaca tatcgccacc tggagtagca
     3841 atagttactt catcattttt acgtttgcca atcaatgctt gcgcaatagg agaatcattg
     3901 gaaattttgc cagaaaacgg atctgcttca gcgcttccga caatcgtgta ctcttcttct
     3961 tctccatctg gtagttcgat gaatgtaact gttttaccaa ttgatacctc atctgcatct
     4021 acaccgtcgt tatcgatgat ttgagcaaaa cgaatcatat tttcaattgt tgtgattctt
     4081 ccttcaacaa atgcttgttc atctttcgct gattcatatt cagagttttc ggaaagatct
     4141 ccgaaaccgc gggcaatttt gattcgttca atgatttctc cgcgtttgac tgtttttagt
     4201 tcttctaatt ctttttctaa tttttcttta ccttctagag tcattggata aactttctct
     4261 accatgtgta acgtctcctt ttttcgataa aataccgcaa aaggtaatct tttgaggaat
     4321 atagtccaaa aaagattacc acgcttttct tcaaatgtaa atgtttttct aaaaatgatc
     4381 aatgtctaga gcctgttttt ctaagaatta tttacatatt tttccactaa ttccatatgt
     4441 tcttcataag ttttagcgaa ataaacattt ccagtgctcg tatctgctac gaaataataa
     4501 tagtcatttt ctgctggttc taatactgcc ttgattgcct cttcgcttgg attgtcaaaa
     4561 ggtccaggtc catagccggt attggtatac aaattatatg gtgaatctac agctgtatct
     4621 tcatacgtca ctaattcttt gtgttcacct aatgcgtata aaacagagat atctgactga
     4681 agtggcatat ttgctttgat tcggttaaag aagacttgtg caatgttttt acgatcattt
     4741 tcttttacgc cttctttttc aactagagaa gctagagtta aaacttcttg tacagtcaaa
     4801 tttttctgct tgatagctga ataatagttt tgcatgaccg tattcgtctt gttcaccatt
     4861 tcaatcacta gatccttaag cgaagtactc gtgtaataat catatgtggc tgggaataag
     4921 taaccttcca aacggtattt tgtgttctca gctttagatg cactttccaa cagttctggg
     4981 aatttttggt gcaactcgtt aaagaaagtc tcatcattca ctaaatctaa aaattctttc
     5041 ttgtctttac cagttacctt cgctacccgt tcagcaatct gatcgatatc gtacccttct
     5101 ggaatggcaa ttttcccatc tgcaactttt gttggctcag aagtaccgcc ttcttgcaac
     5161 tgtttgccaa tctcgtcaag agtcatatta ggcgctaact gataatagcc agcttgaaag
     5221 ccagttaaat ttttaaattt tgtataataa ttgaaaacaa tcccgctttt aataatattg
     5281 tccttctcca aaatctcacc aatctgcttg ttagaagagc cactcgggat ctcgacttgg
     5341 actaattggt catctgattt atctaaaggc ttcaacccgc tatctacata acgatacacg
     5401 gtaaatccaa gaaatccgcc aataatcaat aatgtaagag caatcactaa aatgatcttc
     5461 ctcacaatct tatcttcttt tttacgcaga tttctccgct tgtcgattat atctgctgta
     5521 gctgccttac tggcttcttt tttatcttta cttgggtgtt gtttgtttcc tgacaaaaca
     5581 actcctcctt actatcaagt tcgtaacttt attcattata catgatattt gaattggcgt
     5641 gaatgatttt atttaaatat tctatcaaaa atgtaagtag taaatccatt actataagat
     5701 taaaataaat gttatcaaga tacaagctat tttagcttta ttctttctgt aaaaaagaaa
     5761 ggagactaaa taaactatta tgaaaaaagg aaaacatgct aaaaaaagaa aatattcatt
     5821 tttaatgatc gttgtcgtgt tgtttagcct tagtgcgttc tctacaggaa ctattcttgg
     5881 atggcaattt tacaataatg aacactctca gatagttgcc catgctcaat cagctcaaaa
     5941 aaagttgata ctgactacca atgaacaaca gctcgttgaa aaaatcgatc aactattaag
     6001 aaaaaatgat tatattggct caatttacgt aaagaaaaat aatcgcatca tcatggaaaa
     6061 aggctatggc tatgcgaata aactcacgca acaaccaaat gatccttctc tttattatca
     6121 gattggttcg gttcaaaaag cattgactac tcttttgatt ttaaaacaag tcgagcgtgg
     6181 gcacctttct ttagatacta agctggctca attctatcca caaattgctg gcagccagca
     6241 aattactatc cgtgacttgc tgtatatgcg ctcaggcttg caccgaactg cttctccaac
     6301 cataccgatg actgatgaag aagtcgttca atttgcgatt cagcacttaa aatttacaga
     6361 ttatcagacc tctcattatg attcattgaa ctttaccata ttgactggaa ttttgatcaa
     6421 attaacaaat caaccgtatg aaaaattatt gaccgatgat atcatcgaac ctttaggatt
     6481 acagcataca aaattttatg accaagtcaa aaattcatcc aatcatgcac tatcctatca
     6541 aatgtctaaa gaggatgatt actttaaacc actgacagaa tctgaaacag agatccataa
     6601 cgaattaggg actggtaata tcagtatgtc cgtctatgat ttaaatacgc tgtttacaca
     6661 agttttatct ggaaaactag tttccaaaga cttactcttc tcattatggc gtgaaaatgc
     6721 gaatggacat ccatatagtg gtggggtata tagcggagat aattatatcc tgtcgcaagg
     6781 aaatatcgac tcttttgata catctgctat atttagcaaa gattcacagg atgctatcat
     6841 catggaaagc aatataaaag ctgacaaaac tatcaaactg cctactgctg atctaagaaa
     6901 ccaaatctat gacctgatgg aaggaactac taagttggca aatagctgat atgatgaaaa
     6961 gatagcaaat actacttctt tgaatagcat ttgcttaaaa aaagtactcg actaaacgta
     7021 ggaaagagtg tgggacaaat ctaaaaatca atttttgcta cagactttaa ttccaaataa
     7081 acagaacaga aagaggtgtt cttctttctg ttctgtccaa attattctaa gatttctctt
     7141 taccaacatt atttgacaaa gggcctatta aatctaaaat agtatcttta gattgctaaa
     7201 atatgtgcta gcaaatcatt catggcttgt tcttattttt aattttatgc aataaaaaag
     7261 aagaacaatt agcgtgatta tagaaataaa taatgagatt ttagaaaaaa atgtgtatga
     7321 atacctgatt gttactttat ttattccact ttcacttttt actgtaacaa aaggacctcc
     7381 ttgttttagt actgtagcat tttttgaatt aacagtaacc gttaatcctt tataccggaa
     7441 tacaggtaaa actattgttt tgccttttga agatttaagc gtaaatgtaa tttcatcttt
     7501 atttggagaa aagctactat aaataacttg accatcttct gtaacttgat ggtttttcaa
     7561 aagcaattga tcttttttat agcctatagg tacataatca aaattctcaa attcttcaag
     7621 tttattttcc atttgttcat tagaataagt tccttgaaaa ttcatttctt tcaccatgtt
     7681 aactactgat gaataattta aaattgaaat agctaatatt aataatagta taaaatttct
     7741 tctccttgta taagaaaatt tttccaactg tggagaaata aatagagata ctgaaaaaga
     7801 tatgaacaat gttgaaaata tcataaaacg ccaaggagct tgaataatat ttaaaggagt
     7861 attttgtaag gcaaaccatg gaaatatttt tgtacaaagt agaatagata ttatacccat
     7921 tatataagtg attttagata agattcctaa ttttttaaag ttaaatgtta gtataattaa
     7981 acaaataagc aaagttaagc caataccaaa tgatagtaat tctgaatcta tacttccaat
     8041 caaaaactct ttacccagat aaattgctct tttttgtaat atatccacat aaggtctatt
     8101 cagatcttga tacaatgtct gctcaatcat aggacctata aacgctagtg aaagaagtaa
     8161 agtaactata gcagctttta ttaatttaat aattaagaag atttctattt tctttttccg
     8221 ataaaattga ataattaaag caattataat cattaccata gtcatagcta cagaaagaac
     8281 atgagtgtaa attaataaag tcatgctaat cgccaacata acccaagatt ctttttttga
     8341 gtcgtaaagc tttataaacc cgagtaaaat aagaggaagt attgacattg cgagtaattc
     8401 ccccattgcc cctcgaagaa atatttctac actcctaaaa gaagatgttg tatatataat
     8461 agcgaaaaag gagctagtaa catgtttttt ggtaatttca tacattacat aatgacatat
     8521 aaatagagta atgagcgtaa caatataaag aaaaaggtta tagcctattg ctaaattagt
     8581 aaacttgatc aataaaaata aaggatatag agttaaccat gggtaaaaat tatttacttg
     8641 catgccatat gatctaaacg tttcaaaatt aataggggag ctaaaaatag attctaaact
     8701 taacgcacga ttaatgtgaa atgccgtatc ataaaagcca aatatttcca tgtttttaaa
     8761 tgctggaaat aaatataata aactaacaaa tgcataaact ataaatattt ttacagaaaa
     8821 aatttttttc aaattcatat accacctcat gtttttttat attacatata gtatcattta
     8881 tttttttaaa acactagatt agtcactata taaaatgtga ttaattttat tattaataaa
     8941 atatttttta tattacaaaa gtagtgttt
//
LOCUS       DARPZF010000076         8676 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.079, whole genome shotgun sequence.
ACCESSION   DARPZF010000076 DARPZF010000000
VERSION     DARPZF010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8676
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.079"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            2..74
                     /locus_tag="SLE65_002524"
     tRNA            2..74
                     /locus_tag="SLE65_002524"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="SLE65_002525"
     tRNA            78..150
                     /locus_tag="SLE65_002525"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="SLE65_002526"
     tRNA            155..225
                     /locus_tag="SLE65_002526"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="SLE65_002527"
     tRNA            238..311
                     /locus_tag="SLE65_002527"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="SLE65_002528"
     tRNA            323..394
                     /locus_tag="SLE65_002528"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     regulatory      583..662
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            660..1853
                     /locus_tag="SLE65_002529"
     CDS             660..1853
                     /locus_tag="SLE65_002529"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEI8449776.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="SLE65_002530"
     CDS             1983..3455
                     /locus_tag="SLE65_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8449777.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="SLE65_002531"
     CDS             3538..4326
                     /locus_tag="SLE65_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEI8449778.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="SLE65_002532"
     CDS             complement(4393..5061)
                     /locus_tag="SLE65_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEI8449779.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..6888
                     /locus_tag="SLE65_002533"
     CDS             5176..6888
                     /locus_tag="SLE65_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8449780.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6891..8663
                     /locus_tag="SLE65_002534"
     CDS             6891..8663
                     /locus_tag="SLE65_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8449781.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         2611 a         1483 c         1932 g         2650 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattttttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtagctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agcacaattg
     6301 atccctcgtc tatttgatcc gacagaaggc aaagttgaag taggtggtgt agatcttcgt
     6361 caagtaaatg aaaagagttt aagacaaacg gtttcctttg ttttgcaaaa agcaatttta
     6421 ttctcaggaa cgattgctca aaacttgcgc caagggaaaa agaatgcaac agaaaaagag
     6481 atggaacatg cttcttctat tgctcaagca aaagaattca tcgaaaagtt atctgatcgt
     6541 tacgaagcac caatagaaga acgtagcagt aacttttctg gtggtcaaaa gcaacgttta
     6601 tccattactc gtggcgttat cggtaatcca aagatcttga tcctagatga cagtacgagt
     6661 gcactggatg ctcgctctga aaagctggtc cgagaagcac tcgatcgaga tttgaaggga
     6721 acaacgacga ttgtcatcgc acaaaaaatt gcttctgttg tcaaagcaga ccgcatctta
     6781 gtattggatg aaggcagatt agtcggcgaa ggaacccatg aggaattggt agctggaaac
     6841 cgtgtctatc aggaaatctt tgaaactcaa aaaggaacgg aggagtaagt atgactgatc
     6901 taataaaagc aagtaaattt ttctatcact atttgaagcg gtacaaactc tcctttttct
     6961 ttatctttat cacagtgatc attgctacct atctacaagt aaaggcacct caatacatcg
     7021 gggaagcttt tcaagaatta gctaattacg taggaggctt gatgcaaggc gtagacgata
     7081 aaagcaaatt tgtttctgta atatggaaac tcttgctgtt ttatgtacta gctagtgcag
     7141 ccaactttat ctatagtatt ttgttcacac aagtagtagg gaagtcaacg aaccgaatgc
     7201 gtatcggtct attcaacaaa ttggaaaaat tgacgatccg tttctttgat tctcatcaag
     7261 acggtgaaat tttaagtcgt tttaccagtg acttagataa tattcaaaat agtttgaacc
     7321 aagctttgct tcaagtcatc acgaatgctg ttttacttgt cgggatcttg atcatgatgt
     7381 tccgccaaaa tgtagagtta gcttgggcta caattgcttc cactccagta gccgttttga
     7441 tagctgtctt gattatccgc aaagcacgga aatatgtgga tcttcagcaa gatgaagtgg
     7501 ggaaactaaa tggttatatg gatgaaaaaa tcagcggaca acgtgtcatc atcacaaatg
     7561 gcttacaaga agaaacgatt gaaggattct tagagcataa tcaaagtgtt cgcgaagcaa
     7621 ccttcaaagg acaagcttat tctggtctac tatttccgat gatgcaagga atgtcactgg
     7681 tcaatacagc gatagttatc tttttcggcg gctggttagc attaaatggt gatttggaac
     7741 gttcggtggc attaggctta gttgtgacat tcgtccagta ttcacaacaa tattaccaac
     7801 cactgatgca gatttcatct ggatacagca tgatccaatt agcgattaca ggggcaagac
     7861 gattgaatga aatatttgat gaaaaagatg aagtcaaacc agaaaacggt aaagcatttg
     7921 atggtgttga aaaaggtctt gcgttgcagc acgtagattt tggttattct ccagaaaaac
     7981 tagtcttgaa agatgtctcg atcaatgtgg acaaaggaga aatggttgct cttgttggtc
     8041 caacaggatc ggggaaaacg acgatcatga atctgctaaa ccgtttttac gatgtcaatg
     8101 atggttcagt agtcatcgat ggaatagata tccgagatta tgatcttgat gcattacgta
     8161 gacatgtagg aatcgttttg caagaatctg tattgttctc cggaacgatc aaagacaata
     8221 tcacattcgg caaaccggac gcttcagatg aagaagtcat caatgcagca aaacaagcga
     8281 atattcatga cttcatcatg acgttagaaa aaggttatga tacagagata tccgaagaaa
     8341 ataacttatt cagtacaggt caaaagcagt tgatcagtat tgctcgaacg atcatcacaa
     8401 atccatcttt attgattttg gatgaagcaa caagtaatgt agacacggta acagaagcaa
     8461 ggatccaaaa agcaatggat gaagcaatca aaggaagaac cagctttgtg attgctcacc
     8521 ggctgaaaac aatcttgaat gcagatagaa tcgttgtctt gcgtgatggg gaagtcattg
     8581 aagaaggcag tcatcatgag ttattagcag aaaatggatt ttatgcggaa ctttatcata
     8641 atcaatttgt atttgaaagt taaattaaaa gaacct
//
LOCUS       DARPZF010000077         8661 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.080, whole genome shotgun sequence.
ACCESSION   DARPZF010000077 DARPZF010000000
VERSION     DARPZF010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.080"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(178..735)
                     /gene="frr"
                     /locus_tag="SLE65_002535"
     CDS             complement(178..735)
                     /gene="frr"
                     /locus_tag="SLE65_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEI8449782.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(738..1460)
                     /locus_tag="SLE65_002536"
     CDS             complement(738..1460)
                     /locus_tag="SLE65_002536"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEI8449783.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1596..2477)
                     /locus_tag="SLE65_002537"
     CDS             complement(1596..2477)
                     /locus_tag="SLE65_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEI8449784.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="SLE65_002538"
     CDS             complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="SLE65_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEI8449785.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3717..4196
                     /locus_tag="SLE65_002539"
     CDS             3717..4196
                     /locus_tag="SLE65_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HEI8449786.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4413..5504
                     /gene="phnW"
                     /locus_tag="SLE65_002540"
     CDS             4413..5504
                     /gene="phnW"
                     /locus_tag="SLE65_002540"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HEI8449787.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5497..5625
                     /locus_tag="SLE65_002541"
     CDS             5497..5625
                     /locus_tag="SLE65_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HEI8449788.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGTQLTDKEIR"
     gene            5629..6174
                     /locus_tag="SLE65_002542"
     CDS             5629..6174
                     /locus_tag="SLE65_002542"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HEI8449789.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6628..8319)
                     /locus_tag="SLE65_002543"
     CDS             complement(6628..8319)
                     /locus_tag="SLE65_002543"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEI8449790.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
BASE COUNT         2410 a         1771 c         1568 g         2912 t
ORIGIN      
        1 ttaaaagatt cccactatct taagtattat agcaatatct aactgttttt cctatgaaat
       61 cattgttttt ttatttaaaa actgaataat tttttctttt tttaattttt aaataaaaga
      121 aatataaata aaaacagagg aagcggaatg atccgcccct ctgtttttat gattttatta
      181 aacttccaat aattcttttt ctttatcagc agcgatctta tctacttctt tgatgctgtt
      241 atctgtcaat gtttgtacgt ctttttctaa tccgcgcaaa tcatcttcgg taatatcacc
      301 atttttttgt tgttttttat attcatcgat cgcatcacga cggatgttac gaatcgcgat
      361 ttttgcattt tctgcttctt ttttcacatc tttagctaat tcttttctgc gttcttctgt
      421 cagttgcggg ataactaagc gaatgacatt tccatcattg gttggactga ttccgatatc
      481 acttgccata atagcttttt caacatcttg aagaatgctc ttgtcaaaag gtgtgatcat
      541 taaaacacgt gcttctggaa tttggattga tgccatttgg ttcaatggtg ttggcgcacc
      601 gtagtagttc acagtaatac ggtccaaaag gctagcgttc gcacggcctg cgcggatttg
      661 cccaagttca cgttgaagat tttgtgctgc ttttttcatt ttttcttttg cttctgtcat
      721 aattgcatct gccattttta tttccccctt acagttgttc cgatattttc gcctaagatt
      781 gcacggcgaa tatttccgtg ttcatttaaa ttgaagacaa gcagtggaat atcattatcc
      841 atgcttagtg aacttgcagt tgaatccatg acttgtaatc ctttggcaat aacttccaga
      901 tgagtcagtt cttcaaattt tactgcattt gcatctactt tcggatcagc agaataaaca
      961 ccgtctacat tgtttttagc catcaggata acatctgcgc cgatttctgc cgcgcgtaat
     1021 gctgctgttg tgtctgtcga gaagtacggg ttgccggtac cgcctgcaaa gataacgatc
     1081 cgtccttttt ctaaatgacg ttctgcttta cggcgaatat atggctctgc gatttgacgc
     1141 atttcaatcg aagtttgcac gcgtgtcggt acacccacgt tttccaacgt atcctgtaaa
     1201 gctaaggcat tcataactgt agctaacata cccatgtaat cagcttgagc acgttccatg
     1261 cccatttgtg ctccgatttg tccgcgccag atatttccgc cgcccacaac gattgccatt
     1321 tcaacgccca gctcgtgaac ttctttgatt tcttggatga tttctttgat tactggtggt
     1381 ttgattccaa atcctgcgtc cccagctaaa gcttctccac tcaattttaa gactacacgc
     1441 tgatatttcg gtgtgaccat gttcattcct ccaatatttt ctattgccat tttaccatac
     1501 ttagatgatt tcgacactct aagactggtt tttcttgttt tgcttaaaaa aagggagcgc
     1561 acaaaccgtg cgttcccgtc tgttattcaa cagaattatt ttttcacttg gctcataact
     1621 tcttctacaa agttatcttc gcgtttttcg ataccttcgc caacttcgaa acgtacgaat
     1681 gttttaacag ttgcgccttt tgatgcaacg tatttttcaa cagtcatatc aggatcttta
     1741 acgaatggtt ggtccaccaa agcgatttct gctttgaatt tcttcaagcg tccttctacc
     1801 attttttcaa cgatattcgc tggtttgcct tcgttcaatg cttgttctgt aagaacagtt
     1861 ttttcatgtt ctaattcagc ttctggaatt tgtgattcgt ttacataacg aggattgata
     1921 gctgctacgt gcatagctac gtctcttgca actgtttcgt cagttgttcc atctagaaca
     1981 gtcaatacgg caatacgtcc gcccatatgc aagtatccac caaatgcagc attgtcgtct
     2041 ttttctacaa cttcaaagcg acggaagctg attttttctc cgataacttg agttgcttcg
     2101 atcaagtcag attcaattgt acctttatct gttttgattt tcattgcagc ttccatgtct
     2161 gctggtttgt tttcagcaac aagttctgca atttctttta ctaaatcttg gaacatttcg
     2221 tttttagaaa caaagtctgt ttctgagttt acttcaacga ttgctgcagt gttacctttc
     2281 acagcaactg aagccaatcc ttcagctgca atgcggtcat ttttcttcgc agcctttgcc
     2341 attccttttt cacgtaaaag atcaactgct ttttccatgt cgccttctac ttcaactaat
     2401 gcttttttcg catccatcat tcctacgcca gtcatttcgc gtagttcttt taccatttta
     2461 gctgtaacgt ctgccatgtt taactcctcc tgtgtgtttt tctttttaaa aaaagctgct
     2521 tcaaaggaga gtgaggcttg tcgcccagcc tttgaaacag ctccatcatt caaaattatt
     2581 ctgctgaaga attgtcgcct tcaacaacat ctacgatttc ttcgattgat gttgctgtgt
     2641 tttcttctgt gaaatcttct tcaactactt gatcttcacc ttggtttcct tcgatgaaag
     2701 catcagccat ttttgaagta atcaatttaa cggcacgaat tgcatcgtcg tttgaaggga
     2761 ttactacgtc gatttcatct ggatcgcagt ttgtatcaac catagctacg attgggatat
     2821 ttaatttgtg tgcttcttga acagcaatac gttctttacg tgggtcaacg atgtacatta
     2881 catctgggat tcttggcata tcagcgatac cgcctaagaa tttttcaaga cgttcacgtt
     2941 ctttgttcaa accagcaact tcttttttag gtagaacttc aaaagttcca tcttcttcca
     3001 ttgcattgat ttgtttcaaa cggctgatac gtttttggat agtatcccag tttgtcaatg
     3061 ttccgcctaa ccaacgatgg ttaacgaagt attgtcctgc acgagttgct tcttctttga
     3121 ttgcttcttg tgcttgtttt tttgtaccta cgaataatgc tacgccgcct tcttcagcaa
     3181 cgctcttcat gtaatcataa gctgcatcta ctaatttaac tgttttttgc aagtcaatga
     3241 tgtagattcc gtttctttct gtgaagatat atttcttcat ttttggattc cagcgacgag
     3301 tttggtgacc aaagtgtacg ccggcttcta gtaattgttt catagaaatt actgccatgt
     3361 ttgtttcctc cgatttggtt ttatttttcc tcttcttatc ttctaccttg ccggcaaact
     3421 ttttcaagca cctaccgaca atccaataag aatgtggatt tgctgatgca taaagcaccc
     3481 tcagctatta tacagacaaa agatccgtat cgcaagagca aatatacttt tctgctcaac
     3541 attcaatagt ttacctgaaa gataaaaaga attcaagaaa aacagtagat ttctctttgt
     3601 ttctttatta tcctttttcc ataaaataat tttaggtata aaagacgaat attattgggc
     3661 aatccttctt ttttttgtta tgatacatgt gaaatctttc gtaaaggaga aagaaaatgc
     3721 gcaaagctca aagacatttg ctgattaaac aagtcattga agaattcccg atccgtacgc
     3781 aagaagaact attaaacaaa cttgggcatt atggcgttac cgccacgcag gcaacgattt
     3841 ctcgagatat ccgtgatcta aaaatcgtga aggcacctga tgaaaatggc gtttcccgct
     3901 tcgtattgtt tcgcgaaaaa ggaactcctg agactaggac tgaggaagag gatcggctgg
     3961 ttcaaatgat tgaagacatt gtattgaaag tcgaacgagt ccactttttg acgatcgtca
     4021 ataccttgcc agacaatgct catttatttg catctgtttt agatgagatc aaacctccct
     4081 ctattgtcag tacaattgct ggattcgata cgatcatggt catctcggaa aatgaggagg
     4141 acgcaaaacg agtagaagaa tttcttcacc atccaactga agtatcactt ttttaatcag
     4201 agcacgtatt cctaatatgg aatgcgtgtt tttttatttt caatattttc cttattgaat
     4261 aaacctttac actctttaca aaaatacatc attttttatt caaatttttc aacaccttga
     4321 ttgaatcaca ataatcatca tttatattgg atgttaacaa gagcagcttc ttgctctttg
     4381 tgtatttcaa aaaagaaatg aaaggaaatc atatgtataa attattaact tctggaccat
     4441 tgacgacttc tgaaacagtg aaaaatgcta tgctgatcga tcattgtact tgggatcaag
     4501 aatacaaaga aattacacaa tggataagaa aaaaattatt ggatcttgct caagtatcgg
     4561 aaggaatata cacaacggtc ttaatgcaag gtagcagctc cttcggggta gaatcggtat
     4621 taagttctgt gatcaggcca gaagatactg tactgatttg ttcaaacggc gcatatagac
     4681 aacgaatgat caacatgtgc gaatgtctga aactgaacta taccgtttat gaggtatcgg
     4741 aacatcaaat cctccaagct catgtgatta cacagctgat tgaagagaat ccgtctatct
     4801 ccgcactagc aatggtccat agcgagacta cttccggtat tttgaataat ttggaagaga
     4861 ttgctgctgt cacacaagaa agagatcttt tgtttatagt ggacgcgatg tcaagctttg
     4921 gtgggatacc gatttgtgta gccgaactag ggattgattt tttgatttcc agctcaaaca
     4981 aatgtattca aggtgttcca ggcttttctt ttgtacttgc taataaagcg gaactggaaa
     5041 aacgaaaaaa tgttagccga agtttgtcac ttgatctata tgaccagtac cgcgtgatgg
     5101 aaaacgagaa tggcaaatgg cgtttcactt cccctaccca tacggttttg gcttttcaac
     5161 aagcgctgaa ggaactagag gcagaaggag gaatcgaaac tcgatattca cgttatctcg
     5221 ccaataatca tgtgctacga caaaaaatga cagagatggg gttccagcct ttcattcaag
     5281 aatatcaggg gccattcatc acctcttttc tttaccctaa ggactggcga tttgatttta
     5341 atcattttta tcagtattta aagcaaaatg gatttgtgat ctatcccggg aaaatcagcg
     5401 atcatgaatg ttttcgtatc ggaaatattg gcgagatcta tccggaagat attttggaac
     5461 tgacagcaat tatcaaagac tataaggaga acgttaatga ttaaaactgt aatttttgat
     5521 tgggcaggaa caactgtgga ctttggctgt atggctcctg tccacgcttt tagaaatgct
     5581 tttctagaaa aaggaaccca actgactgac aaagaaatcc gctaaccgat gggaaaatta
     5641 aaatgggatc atatccaaca gcttctttcc ctcccttctg tcaaaaaaca atggatagct
     5701 atttatggac aactacctca ggaaaaagag gtggaggaat tgtatcaaca atttgaacat
     5761 tatctgttta aagatttggt caagcattct accttgaaac ccgacacatt ggaaacgatc
     5821 gaacggttga gaaacgctgg gatcaatatt ggttccacga atggatttaa tgctcctatg
     5881 atgacaatcg tagcagaaac cgcaaaaaaa gaaaggtatt caccagactt catggcaact
     5941 tttgaagacg tcgaagggta tggtcgaccg tttccttata tgatccataa aaacatgcag
     6001 tacttcaaaa acaagtcggt tgatgaagta atcaaagtcg gagatacggt ctcagatatc
     6061 caggaaggga aaaatgccgg agtgttgaca gtaggtgtaa ttgaaggtag ttcgctaatg
     6121 gggatttctt atgatgagta ccaaaaatta gagatgggga aaaagatcgt ttaaaacagt
     6181 ctgttgctct tagattccaa caagccggcg ctgatatttg tgtaaacaat ttaaaagagt
     6241 taacagaata cattttgtac gctgacaaga atccagaatg acttttatac aaaataagag
     6301 gttgtgaaaa agctgtcctg tatcaagtaa taaaaacagc caagcaaaaa tagctcctca
     6361 tatttttcgt ttggttaggc ttattaccgc agatgcaagc ttttgaacac cgtttattcg
     6421 aaaaaaaaaa gggagctgtg acacgacttt tgtcacagtc cccttatttg caaacaaaca
     6481 gtgtttaaga gacaacctct ccactaaacg gtgttcattc agctgactct cggtatttgc
     6541 tcaaaaaacg ataaaatttg aaaagctatt ttctcttttg tttctctaat actcggatca
     6601 gaacgctgat ttcacattct ctttttctta catcttatct ggtgcatgaa gtcctagcaa
     6661 acgaaggtct tctttcaata atacagtcac tgcataaact agagctaagc gtgcttcttt
     6721 ttgttcatca tcagctaaaa tcttcgtatg agcatagtat ttgttgaatg cttgtgctaa
     6781 tttgattgca tgtttcgcaa tcactgacgg ttcgtatttt tccccagcag acaagaccgt
     6841 ttcagggtat ttttgaacta atttaaccac ttcccagctg gtatcgtcat tcaatgcata
     6901 gtctgctgtt tctgaaggga caaatcctgc tttttccaac aggctgactg cacgagcatg
     6961 tgtatattgc acataaggtc cagtttctcc ttcaaatcga acaacttctt ccaggttaaa
     7021 gtcaaatgta ttcagtcgat cgtttttcaa atcgtggaaa atgactgccc caaccccaac
     7081 ttgtttagct acagcatctt tgttttccaa atcagggttt ttctcgctga tttgttcttt
     7141 agcagattgg attgcttcat ttaatacttc ttctaataag acgatctttc ctttacgagt
     7201 tgataatttt ttaccacctt gcgtgatcaa accaaatgga atatggtgca tgtcgtcaga
     7261 ccagtcaaag cccatttcct tcaagacagc tttcaactgt ttaaaatgat agctttgttc
     7321 attccctact acatatagag attgtttgaa gtcgtaagta cgtttacggt acaatgcagc
     7381 agctaagtca cgtgtaatgt atagtgtcgc accgtctgac ttcttaatca acgctggatt
     7441 caggtcataa gcagataggt caacgatctc tgcaccttta tcctcgttca gcaaatgttt
     7501 ttcttctaaa agtttgacga tttcatccat cttgtcattg tagaaagctt caccgttcaa
     7561 cgaatcgaaa cgtacttcca gcagatcata gattttattg aattctttca tcgattcatc
     7621 acggaaccat tgccataatt gaatagcctc tttatcgcct tcttccagac gtttgaacca
     7681 agcacgagct tcttcattta attctggttc tgtttcagct acttcatgga attggacgta
     7741 taaacgaagc aattcattga ttggttctgc tttaacagct tcttctgtac cccatttttt
     7801 gtaagcgacg atcagttttc caaactgtgt tccccagtca cctaaatggt tgatgcggat
     7861 tggctgataa ccgatttttt ccataatgaa accgatcgaa ttaccgataa ctgtcgaacg
     7921 caaatgtccc attgagattg gtttggcaat attaggagaa gacatgtcga ttggtactgt
     7981 tccttgattc ccgatgttgc tatccccata atgttctttt tctttcacta ctgtttgcaa
     8041 aacttttttg ctgataagtt ctttattcat gaaaaagttc aagtaaggtc cgacaacttc
     8101 gattttttca aagttggcag aatcgatttt ttctgctaaa tctgcagcga tttgctgtgg
     8161 cgcttttcgg taaacttttg ctaatgaaaa ggctggaaat gcaacatctc cgtgttcagc
     8221 tgattttgga ttttctagta attgctcgac ttgttccagt gttaaatcat ctttgacagc
     8281 gtcatagaca gcttttgcga caagatcttt attattcatc tttattcctc ctaaagtgtt
     8341 cccttgattg ttaaacaaaa aaaatctcta gcgacggcat acttagtatg ccatcactag
     8401 agacgagatt tcccgcggta ccactccaat tgtcctaaaa aaggaccagc tccatctgat
     8461 atcggtagac gaccgtctgt ttaaaacaga attctccaag tgcgcttcgt tgtatcttct
     8521 tcattcggct tccaccactt ccgaattcgc tagccaagaa tgatacaagt actctcttgt
     8581 tcaacaaatc ttagtcttat taaactttct tgaattatat cagaaaaaaa aacgaaaggc
     8641 tagtcgtttc ataaaaaaaa a
//
LOCUS       DARPZF010000078         8611 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.081, whole genome shotgun sequence.
ACCESSION   DARPZF010000078 DARPZF010000000
VERSION     DARPZF010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8611
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.081"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(611..928)
                     /locus_tag="SLE65_002544"
     CDS             complement(611..928)
                     /locus_tag="SLE65_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEI8449791.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            complement(929..1183)
                     /locus_tag="SLE65_002545"
     CDS             complement(929..1183)
                     /locus_tag="SLE65_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEI8449792.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEDNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            1542..1946
                     /gene="tnpA"
                     /locus_tag="SLE65_002546"
     CDS             1542..1946
                     /gene="tnpA"
                     /locus_tag="SLE65_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HEI8449793.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
     gene            1963..3111
                     /locus_tag="SLE65_002547"
     CDS             1963..3111
                     /locus_tag="SLE65_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8449794.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTIALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            complement(3334..3552)
                     /locus_tag="SLE65_002548"
                     /pseudo
     CDS             complement(3334..3552)
                     /locus_tag="SLE65_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(3818..4012)
                     /locus_tag="SLE65_002549"
     CDS             complement(3818..4012)
                     /locus_tag="SLE65_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449795.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(4112..4198)
                     /locus_tag="SLE65_002550"
                     /pseudo
     CDS             complement(4112..4198)
                     /locus_tag="SLE65_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            5364..6404
                     /locus_tag="SLE65_002551"
     CDS             5364..6404
                     /locus_tag="SLE65_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEI8449796.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESGISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYE
                     SSPSTITKDWLE"
     gene            7228..7560
                     /locus_tag="SLE65_002552"
     CDS             7228..7560
                     /locus_tag="SLE65_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEI8449797.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            8179..8520
                     /locus_tag="SLE65_002553"
     CDS             8179..8520
                     /locus_tag="SLE65_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HEI8449798.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         3051 a         1301 c         1437 g         2822 t
ORIGIN      
        1 tatatttttt accagcaaac catacatatc ttttttcatt aagtatgttc actatctctc
       61 ctccattaat tatatttagc atcaaatagt tattgtacct atattttatc ccattccttt
      121 taaaacaaga atacgtacaa agtaaaatgt tgtaaatagt ctagcaggga agtatatttt
      181 catgtaccaa cataatattt aagaagtttc ccatagatat attggacttc ctcttttaaa
      241 acacaaaaat aaatactacc ttatttaggt agtatttatt aaaagttacg tcaattttga
      301 ttaaaaatat actacttgaa cctctcatga gtaaagtcac gaaatttttg ggaatagagc
      361 gtacttgata tcttattttt tcactaatag cagtgtctct tattcaccaa gcgatccccg
      421 tagttcctaa ggttcttaat ttttctctag actaatgatt gtatctttag accttcggcc
      481 ataacatgga gcaaaataaa aaggtactaa gtcttatata tcaatcttcg agtaaccgac
      541 ggttaacaac catatcgagc ggcattaatc acccacctgt agaggatgag cgactttttc
      601 ctaattattg ttaaaagcct agtttcattt gtttagattg gaaaatacgt cctacaagta
      661 tctctttttt ttcatggtcg atccgataaa ataaggcata gcttttgccg atcacgatcc
      721 gatatgttgg gatatccatt ccatagattt cggaaacttc ctcatgcata gttggaaaat
      781 ttttggttag ttctaaagcc ttctggatcg cacctacaaa tctttttatg ctggctggag
      841 aaagagcaag ctcattttcc cattcttcta ttatcgtttc aaggctggtc tgaaaacttt
      901 tagaataaac tagcgtgtac tctttcatct attcactcca gccgtatttt ccgaaagctt
      961 ttaccatttc aatttctgaa actgttaaac ctttctcaaa gtcttggaaa ctttcttcaa
     1021 tcaatttgcg atcgtgttct tttgctattt gagtagtatc taatatgaat aagttgtctt
     1081 cttgtttggc ttggataatg tctccgcttt ttaatccaag agagcttgga aggatcactc
     1141 ccacgctatt gccgatcttt ctaaccttta gttcttttcc catgttatca cactcctttt
     1201 agtttttgat gaataaatta taacatgtta taacaacaat tgccaacggt gtttcttaag
     1261 ggattccact ccatattatt attggacaaa ataagccact tagaacgctg aaaacatata
     1321 caaacgatat caaaatacga gtgaactact caccatacac ttccgttaac atccatttaa
     1381 cagaattagg cagaagtcgc ccatcctcta taggtgggtg atgaatgccg ttcggtatga
     1441 gggttaccgt tggtaactcg aagaccgaca actaaggcgt attgcctttt tattttgtcc
     1501 catgttacaa tcagtctata caagaaatga gttgatataa catggaatta gatacaaata
     1561 atcattcagt atttcttctt tattaccacc ttgttttagt aacgaaatat cgtagacaag
     1621 tgattgatga tgaaatatct gattatgcca aaactacttt tgaaagaatt tcagaatcgt
     1681 atcacattac tttagtggag tggaatcatg ataaagacca cgttcatatt atgttcaaag
     1741 ctcaacctaa aacagaattg acaaaattca tcaatgccta taaaagtgcc agctcaagat
     1801 tgataaaacg tgactttcca agagtcaaac aatttctttg gaaagaaatg ttctggtcta
     1861 aaagcttttg tcttctgaca actggtggcg caccaattga tgtgattaag aagtatatcc
     1921 aaaatcaagg aaacaatcat aaatagaaag taggtgaact ttatggaaca actaaaagca
     1981 tacaaattca gaatctatcc aacagaggaa caagaaatct tctttgccaa atcttttggt
     2041 tgtgtccgta aggtctacaa tctaatgctt gatgaccgaa aaaaggcgta tgaagaagtt
     2101 aaaaatgatt cttctaaaaa aatgactttt ccgacaccag ctaaatacaa gaaagaattt
     2161 ccgtttttga aagaaattga tagccttgct ttagccaatg cccaacttaa tttagataaa
     2221 gcatacaaga atttttttcg ggataaatcc gttggatttc cacgtttcaa aagtaagaaa
     2281 aatcctgttc agagttatac aacgaataat caaaatggta caattgcttt gattgatagt
     2341 aaattcatca aagttcctaa attgaagtca ttagtaagaa ttaagcttca tagacaacca
     2401 aaagggatta tcaaatctgc tacaatatca cgtcattcta gcggtaaata ctatatttct
     2461 ttgttgtgta aagaagaaat tatcgaatta cctaaaacta attccacaat tggtattgac
     2521 ttaggtatta tggactttgc gattctttct gatggacaaa aaattgataa taataaattc
     2581 acgtccaaaa tggaaaagaa actaaagcgt gaacaacgca aattgtctag gcgtgcttta
     2641 ttggctaaaa ataaaggtac caatctattt gaagctaaaa attatcaaaa acaaaaacgc
     2701 aaagtagcta gattgcatga aaaagtaatg aatcaacgta ctgattttct gaataagttg
     2761 agtacagaaa tgatcaaaaa tcacgatatt atctgtattg aagacttaaa cacaaaaggt
     2821 atgttgcgaa atcataaatt agctaaaagt atttctgatg tttcttggtc aaagtttgtg
     2881 actaaattac aatacaaggc tgactggtat ggacgaaaaa tcatcaaagt agataaatgg
     2941 tttccgtcta gtcagatttg ttcagagtgc ggacataaag atggcaagaa atctcttgaa
     3001 attcgagaat ggacttgtcc tgtttgtcat actcatcatg atcgtgatat caatgctagt
     3061 atcaatattc tgaccgaagg tctaagacta cattctatgg gattggctta gatccaatca
     3121 tcaagaaccg taggaactac ggggatagct tggtaaataa gagacaccgc tgttagtaaa
     3181 gaaatacgct atcaagtatg ctctattccc aagaagctcc cacttcaagc gttaagaacc
     3241 gtcaggttta gctaagtggt gagtagttca cgtaggtatt tttattatat atagatttaa
     3301 catatgtcgg tcggttgatt gatatagcta aagttataac tcaaccgaag ccgattcatc
     3361 tacacgaata aagttgcgag tgttctcggc taattcataa aaattgttat gtgttccata
     3421 tagcaatact ggaataactt tattttcttg aatctcataa gcaactctat acacggtgac
     3481 cgcatactta aatccattag accaattacc tgataaacct ccagtttttt gctcttactt
     3541 aaatggatca atggcaattt catcacaaac ctatagagga tgagtgactt ctgcctaatt
     3601 acgttaaaaa atattgaaag taactctatg tagcaaaaaa tatctagaat ttcatttcct
     3661 caaaactgat cgatattgta tctaaaaata tatactacct aaaataggta gtatatatta
     3721 aaatatgtgc ttttgttaga aaaatcaata cataaattat catatctgta tatgtcattt
     3781 aggtatttca gttatgttat aatagttttg ctgtctgcta ccccggccta atctggcaag
     3841 gggaggagga gatataatga aatacctttt tgattttgtt tttgcaatca agccacttgc
     3901 agatgtagtg tgcagttacc tctgcaaatg gcttgattgc aaaattgcca aaaaagacag
     3961 taagcctacc cgttaattct ataatataga aacgtaaaaa aaaccccatc agcctgcacg
     4021 ctgatggggt ttggtgatat aatgaaatac ctctttgtta ctcataattg taccataatt
     4081 agtcacgaat gcaaccaata gaaaaaacta cttagaacgg tagatcatcg ctaataacaa
     4141 tgcattgtcc accaaatgga ttttgtgaag cattaaatac attgttatta attgtcgctg
     4201 cttttaacta ggcctctccc cttctattat aaaagaagat atatatcatt tcttaattac
     4261 ctactacctt aaaccaaaat ttaagtacta cctaatttaa gtattactta aacaatctaa
     4321 aaaatagtta tcccaattgt tatgctttta taatacgatt atttgtaaca aaatgaatat
     4381 tatataatta aacactacca tatttaggta gtgtttaatt attagcaaaa caaaaaatat
     4441 ttattctatt ctcttaactt caactaagtt atgctgcaca cctttatata aatcatatgc
     4501 aactcattag ctagacaaac tacaagcatg tagttttatc tgttaattat gtactaccta
     4561 aataaagtag tttataatta gcaagtatat atatttaaaa atttaagatt aattttttta
     4621 tgacttgtac aaatttatct gatattctct tattaagaac tacctaattt gggtagttct
     4681 tattttttac attttaagta gtatttaatt gcaatttggt agtatttttt tattatctta
     4741 ttcttagaac ggtagtactt aatataaata taggtagtat ctaatttaag tattaatggt
     4801 agtatctaaa ttaacaggta gtatgtaact actttaaagt aatttttttc agattaacac
     4861 agtagtatct tattaaataa gttaatttta atggtagtac ataattatta tatatatctg
     4921 acattggtag tacttattgt attttttagt agtatataat ctattgtttt ctagcctaaa
     4981 gccttgtctt ataagaataa tataatatat actactgaaa taaggtagta tatattacta
     5041 gtaatggtag tatgttttat atgcataagg tagttcttaa tttatttttt gttttgacac
     5101 tggtagtact taattatctt taattttaaa actaaatttt attcatacgt ttttctggta
     5161 gtatttaatt ataaataata tttatttaaa gtagttctta atgactttaa aggtagtaca
     5221 taattcattt tatttctgat tttaggtagt atttaattaa aaaacagttt taatgcgttt
     5281 gcatttttta tttatctttg ctattttcga aaagagtagg taattttaca taaataaaac
     5341 aacgtgaaag tagaggatct acaatgactg attttaaatt ttttaaggcg gatagagttt
     5401 acaacgaatt attttatcaa tttccaaaag tctttattgt ttctgacgaa tacaaaaaaa
     5461 tgaaagattc aactaagatt gcctatatgc ttttaaaagc aagattagag atcgcaatca
     5521 gcaaacggca aatcgatgaa gaaggtaatg tttattttac ttatacgaca aatgaactat
     5581 gtagagtatt aaactgccaa aaacaaaaag cgatagcaat caaaaaagag ttggaatcct
     5641 ttggtttatt attacaaaag cagatgggat ttaacaaaca gttagggaaa aataatccta
     5701 atagactata tctagcagaa ttaaaagtct cagaaaatga tatctactta ctcgaaaaat
     5761 ttgatagaga gaatagggaa aacgttgata aatcagaggg tatgaaaatc atacccaccc
     5821 tcgacgaaaa atcagacgct gaatcccttg gggctcaaga gggtatgaaa atcataccgt
     5881 gccaaaacgt tgataaatca gagggtatga aaatcatacc agaacttaat aataatatat
     5941 tagacactaa tagacacaat atagacactg aaaaagaccg cctacaagat caattgttgt
     6001 tagacaattt tgagacaatt atgacaaacg acagcattgc tacgtttgtc cctgaacgag
     6061 tattaaattt gataaaaaca ttttcttcaa gttacagtga agctcaaaaa accgtccaga
     6121 ctattcataa tgcaaagaaa aaagctgaaa tagaaagtgg tatttcgata gtttttgaag
     6181 aactcgatag ttattatgtc aatgcagaac aagaattata cacgacactg ttaaaagcct
     6241 atcaaaaatt aaaaaccgaa aaagtcgaaa atatccagaa cctgattttt gtctatgtaa
     6301 aaaattggtt tatcgaaaaa ccaatagctg ctaaagtatc aagtgaaaaa cgtttgaatt
     6361 atgaaagctc cccaagcact attacgaaag actggttaga gtgaaacttt actgacaaag
     6421 tgattgttgc ttcatggagt aacattaaaa ttaaaaattt tttattattc taattatatt
     6481 acgaatatta caaaataata gctattttaa tagaatttat aagttaaaat attatgataa
     6541 aaatcacaaa cgtagccttt tacgtcataa gtgttaaaag aaataattaa tttcaaatat
     6601 agaaaaggga acgtatgttt gcatactcct tttttttgag ttataataat acgcgaagag
     6661 agataatttc attatttaaa caagctaaaa atcttgatat tacttctttt caggcaatac
     6721 gaatattatt cgcttacatt ttttgtataa atttaattgt ctgctatgct tgtgatgaat
     6781 tgattttcgt tctgcacttt tggatgataa atttggacaa ttgaaaatac aaaaaaaaga
     6841 aaggcggtat gaactcggaa ggctggtaac cttcgtcagc gttcatacac ggcattaaga
     6901 tttggccctt aatgcgttaa cctttcagtg ttacggtatt acccgcaatg gatttagtat
     6961 aacagatatt caaaagtgat accacttttt ttggctgtgt taaggttaaa aatacgtgat
     7021 attacgatga atctatgcct aagcacaatg ttataaaaat gtccgtgtgg ctctttgccg
     7081 tatgacgaac gctgaaatta gagggaacgc atgtttggat gcgttccctc ttttttgttt
     7141 gtcatgaacg aaaatcaatt ctctattttt gaaaaataac aagaaaaact tgttaaaaat
     7201 atttaaagaa attgggtggt ttattttatg tcatatacag gaattttgag tctcaaagat
     7261 atttgtcact acggtaaacg gtgtaccgct acagagaaaa tcacgaagaa actatcaact
     7321 ggccaaagta aaaccgttgt gcagtgtaag aaatatataa tccagaaaga caaagtctca
     7381 gaggaaatga tttattacat tgggaaacaa aagcaaataa ttttaaaaga tcctatcccc
     7441 ttaaaagagc tatatccaac aatcaaacat gtttatgacc aaaacggtgt actgattggt
     7501 cgaagaaaaa atggagtctt gcgttgtacc gcaaaaggga tggggcgttt gatcggctga
     7561 attgatcatt ctcataactt gtattttatc gtttttcgct tgcttgaaaa tattgtcgag
     7621 acttctaaag gaacttagag tcactagaaa aataaggagt agacttgatc tatcaacaat
     7681 tcccttcggg gagtgacggg gtaggtttta acgattggta acgtaaaaaa ttggtcaatc
     7741 gagtaaatgc gcttgtttgg atagtggtga aatgaatttg tgtaaataat aagcgcagag
     7801 taaacaagag ggaatttaga agttagacaa gttagaatag cgtctagatt aatcatgagc
     7861 agctactaag ggatctagac tttgacgcaa actcatggaa taaggagtag gtcttctcgt
     7921 aatggggagg acgcacaaga aattgtgtcg tgtgctgcag tacatgtaga tacttgcgag
     7981 gacgttgatt attggatcaa tcgagcattt accgctgtct actagggttt ctcgtttcgg
     8041 acgccataaa cgagtcgaaa ttttttatgt atttttaagt aaacgaaaaa cgataaaata
     8101 tgaacaagtc ctgaataaag tgaaaaaatt gatataaaac atagagaaaa tgaaatttac
     8161 gtaatggagg aatgacaaat gaaaaattat gatccgaata tacgattggg cacacatact
     8221 attaaggttt ctttccaacg ttgggattac aaaggatttg tgacgtttag aagaggcgga
     8281 aattgtaaag gattagatgt tttagcatta gacgaggatg atttatacga tcaaacattg
     8341 actgataatc caattggatt cggcttgcta cctgaagatg atgaaggtaa tgaatggttt
     8401 aaaatgacgc ttatgaatga taatggagac gaattatctg ttgaagatac ttggtcatat
     8461 ttgagtgatt atattgtcag ctttgaaatc attgaatttg tagcggataa agaagaataa
     8521 aaactggagg aataaatttt acagataaag gcttagaagg agtcacgatg attaataaaa
     8581 aggtagtatt accttaggca ttgagtaagg a
//
LOCUS       DARPZF010000079         8609 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.082, whole genome shotgun sequence.
ACCESSION   DARPZF010000079 DARPZF010000000
VERSION     DARPZF010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.082"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..252)
                     /locus_tag="SLE65_002554"
     CDS             complement(<1..252)
                     /locus_tag="SLE65_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HEI8449799.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIACVIWGIINGYTSQRATYRAVCSVLFPNGDF"
     gene            complement(732..1523)
                     /gene="msrA"
                     /locus_tag="SLE65_002555"
     CDS             complement(732..1523)
                     /gene="msrA"
                     /locus_tag="SLE65_002555"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEI8449800.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
     gene            complement(1714..2349)
                     /locus_tag="SLE65_002556"
     CDS             complement(1714..2349)
                     /locus_tag="SLE65_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HEI8449801.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYRLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            complement(2615..3667)
                     /locus_tag="SLE65_002557"
     CDS             complement(2615..3667)
                     /locus_tag="SLE65_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8449802.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(3680..4618)
                     /locus_tag="SLE65_002558"
     CDS             complement(3680..4618)
                     /locus_tag="SLE65_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEI8449803.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            complement(5069..5719)
                     /locus_tag="SLE65_002559"
     CDS             complement(5069..5719)
                     /locus_tag="SLE65_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449804.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            complement(5819..6328)
                     /locus_tag="SLE65_002560"
     CDS             complement(5819..6328)
                     /locus_tag="SLE65_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HEI8449805.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            complement(6413..6892)
                     /gene="rlmH"
                     /locus_tag="SLE65_002561"
     CDS             complement(6413..6892)
                     /gene="rlmH"
                     /locus_tag="SLE65_002561"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEI8449806.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            7320..8609
                     /locus_tag="SLE65_002562"
     CDS             7320..8609
                     /locus_tag="SLE65_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEI8449807.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENIKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
BASE COUNT         2721 a         1736 c         1381 g         2771 t
ORIGIN      
        1 aaagtcacca ttaggaaata agacggaaca aaccgctcta tacgtggctc tttggctagt
       61 atagccatta attatgcccc atataacaca agcaataatc actgtatcgc gttgcttcag
      121 ttgatcagta tttcttcggt ttttaatctt atctggtaca caattgtggt atatgttaga
      181 aacagttctc ataatttcct tgaatgttat aaaagtatct gtataatgtt cagtatattt
      241 tgatgaacgc atatgtagtc ctcatttctt gggagttttg agactactat atgcgttttt
      301 ttgttgattt accaacatgt ttagacattt tcctctagga aaaaattaac tagcaccacg
      361 ggttttatag ttattgtttg cgcttttata cggaatttag ttcatcatta atgtggaatt
      421 cgattaggtg tctattaatt atcaagatga ttctctacaa aattccatag aaaaatcaag
      481 attctacaat tcgaattctc tttcacatgg aaataaaggc tagtaaaaaa acaggagttg
      541 tgacaaaaga cttgtcatac ctcctgtttc cttgcgactt gaagctgaat gctttgcgcc
      601 acaacctttt cctcggtgtt ctcaaagcaa ctcctcgaaa taattcataa ctgtccaaaa
      661 atatgaaaag ctatttttgt cagttgctca ttattttgtc ggagctgaac gctttgcgcc
      721 acaaccttcc tctatctatg tcgctgaaaa aataaatgaa gctgatgcga atgcttgatc
      781 tttttatatc ttttaggttg cttctgataa aattgttgat gatgattttc agctggccaa
      841 aaagtctttg cttggcgaat ctctgtaacg ataggacggc taaatcggtt agattgaatc
      901 agttgttctc ttgatttttc agccaattgc ctttgctttt cattaacaac aaatagaatt
      961 gaacgatatt gtttcccccg atcttgaaat tgaccaaagg catctgtagg gtctgaaatt
     1021 tgccaataaa tctccaacag ctcttcatag gttatttgac gtgtatcaaa tatgatctca
     1081 acagcttcaa catgcccagt atatccacca ctgacttgat cgtaatttgg ttttttggtc
     1141 tctccacctg tataaccaga taacactgag attacacctg gttttgtttc aaaaggctca
     1201 accatacacc agaaacagcc accggcaaaa atcgcccgtt cttggtataa gggtgaagtt
     1261 atcttatgtt tggcataatc ataagccttt gcactcgctg actcccctgt gattcttaaa
     1321 taaaaatcca tcgcatctgg tgtcaaatta tctcgtagtg ctagcggacg caagttgacc
     1381 tctagttttt ctatcacctg ctttatcgac atttttgcta ggtcttcttt tgcctcttca
     1441 aattgtgttc tttcccattc tcttgtattt cgatttaaaa taatattata aaggtctatt
     1501 tccatctgct ccacatctaa catgaagtca ccctctttca agttttcttc ttattcattc
     1561 aaaaaatgac tacctgaaat ttagcacaac gcataacaag ttaagactaa cttgcttttc
     1621 gctctcctca tctctattct tagtcgaaca catccacacg aatggttacc catagagaaa
     1681 ttcttttact taatcagctt cacactgctt tttctacttt cgtagttgaa aaaaacttaa
     1741 acaaatcatc ggcaaatagt taaagaaaaa acttaagcgt tgaaagaagc ccaattgctt
     1801 aaagaaggca aactgactaa tcgacggaat ccgtgctaat ctgtaaagac ctgcaattag
     1861 taaactaata actgttaaaa caagataaaa atggctaagc gtaccttgac cactttgacg
     1921 ataaagcaga acaagtaaca atgggaaaag tagaaagcct gcatagccta gcccagaacc
     1981 tatattatgg atccaagtcg atagattcca agagctttca ttcgtattga tactgaataa
     2041 cccagtaaaa atacaatcac ctatcccata taaaccaact gttgcaacag caagtattgc
     2101 aagtgttttt gatgttccaa taaataggtg atacaacgca ggcaacgaaa gaacaaaaaa
     2161 aagtccagat acaactgacc agaccaagaa agcacgtctg actggactat ctacgtcacc
     2221 aaacacacta attacggtag tcatttgatt cagtttggga taaaaaaggc caaggatata
     2281 cggtgtcgat aaatcactaa tcacacctaa taataaaaaa taaaaaccat atttttgcaa
     2341 aaaaatcatt ttcttctcct actttttagt gattattcga tacatccaac aatcaaattt
     2401 tttctcattt taacacatat ttttattcta gttgcctttt gaacaatcaa taacataaag
     2461 gtgagtttct tctacatttt aaaaaatcga atggcactga agagttcagt tgtcagcatc
     2521 aatctcctac tcaaaaaggc aaaaaaacgt aagtcagatg ttgttgacat ctcacttacg
     2581 catccattga ttgaaaattt cttagtaaaa tctactagcc taaaaatttg aagacttctt
     2641 ctcgatcata cagtttaaat actttctcgc ataaaaattg agtaattagt gccgcaaaaa
     2701 cagggatgac taaccaacaa agaacaacaa gaaagccatt tagccctgca tctaaagaag
     2761 ccaacggacc aacaagtccg accacgccga aaccagcaga agcaggcgta cctgaaatag
     2821 aaaatagagc gacaggaata gctgtaatca ctgcactaac taaacaagga ataagaatca
     2881 caggttttct aaatagatta ggcatcatca tcttcatagc gcctaaagca atcgcaattg
     2941 tcacacctga cttattaacc ttccaagagt tcactactaa aacaaaagtg gttgcagcta
     3001 cgcccatcgc agccgcacca gcagaaacac catctagttg gattgccatt ccgattgcta
     3061 ctgttgaaat aggagagata atcaaaaagg caaaggaaca accaatcaag atagacatta
     3121 acagcggttg taaggtagtg aagttattaa tcaatgatcc aattgcagaa gtaattgctg
     3181 ttacaaaagg gaataaataa aaaccaagta aacctgcacc tacacctaca acaatcggtg
     3241 ttaacacaat cgacactgac ccaaaactat ttccaatcag taaaatcagc ccgacagcaa
     3301 tcgatgctgt cagcatcgta ttaataatat cgcctgtacc agcaccaacg taaacacccg
     3361 tttcacccaa atcaggtgtg aatttgacta caccagaacc aacaaaagaa gctccggcta
     3421 caaccatcat tctcatcgga tcaaatccaa attgtaaggc aatcaaacca ccaatgatca
     3481 aaggtgttgc tagttgaaaa ataactgcta actgtgcgat cgttaccgca aagggatacg
     3541 cactaaaata ttttaaaatg gcacctaata ctgcattagg aatcaatcca ataatgattc
     3601 ctgttgctgt accagcgagg actttattca gaaaaatttt cggtgatatt ttttgtgaag
     3661 tttccattca atctctcctt tattttacgt tcaaactatc ttcttttgca tggacaagct
     3721 cagtcaagaa atcacaataa ggcgtcgcaa caccatattt cttccctttt ctagaaattg
     3781 cgccattgat ataatcgatt tctgttaatc gatggttctt aatcaagtct tgatacattg
     3841 aaggataatg taacccaatt gtttccgggt caaaacaaga ttcacaatgt gcaatgactt
     3901 ctgggacatc tagttcaatc ttctctactg ctgctacttt ggcaaactca ttgacaatcg
     3961 tcgccaccat tttatgagca gtcgatgttt ttcctagctc agccatatta acgtctaaga
     4021 ttgtgcatag tccgttcatt gttccgttca cacatgcttt gcgataaata gaatagtgaa
     4081 tattgtcaga aaaatgagca tttaatcctg attcagacaa tttgtctgct aatttttttg
     4141 cagctgcttc ttttccatca cctaaatttt gtaattctac tgaaccactt ccaaataatt
     4201 tgacctgacc aggaccttca agacctgccg tccacatggt atttccaata tagatatttt
     4261 ccattggtac aaatttctca ataatatctt catgcccgat accatttaat agacataaga
     4321 cctctgtatc ttttttgatt aatgattgga tatcctgcag cattttttcc agctgcatcg
     4381 ctttggtaaa tagaataatc agatcaactt gatcttcttt ttctacttcg gattgaagaa
     4441 cgattggtag ttttgcttct acctctttac cattaaaatt tgcttgtaat ccatgctctt
     4501 tgatttgttg gacatgttct gcccagccat cgattaataa tacttcgttc ccactttggt
     4561 gaagcattaa cccaaagcga cttcccattg cgccagcgcc tgcaattgct attttcattg
     4621 attcttcctc ctttttcttt ctattatatt catttgagaa tcatttcaca accttgtttt
     4681 gttattcttc tcttatttat catgtttata tccaccattc aagttatttt atcagcaaat
     4741 caataaaaac tggaatagaa tcccaatttc atcgtaagag aaactagact agcaataaga
     4801 aaatagaaac attcatagaa aaaacctcac tcctctgatt ataaaagagg gggcattaac
     4861 ctcgtgtata ctaaaacctt ccattcattc gatggatgat tttctttttg tgaaaaaata
     4921 ttcattgtag tacgatgttg cgcaacacag acggatggta ttgcttatta tttattaaaa
     4981 tcgaacaata cacttattta aaaacttctt tcccagattt tcttccattt ttacagttat
     5041 aactagtatt atcatgaaaa atagcctttt attgtctatg ggaataataa tttaaaattg
     5101 gtactttttt attaattagt tcatcgccca ataatctctc cagtttctta gcatctcctg
     5161 actcaaccgg aattatccaa gcccagtcca aataattttt taaaatctca tcatattttg
     5221 caaatatttc attgccatat tccgtcctta aaattatatt ttcagtgcca gacaagtgat
     5281 ttgtattgag ttgataaaaa agatctccat ctaaaaaaat atcattagaa gaagatttcc
     5341 ccacagtaat gaccattcca tcagctctat gtgttacata caaataattg tatgacctca
     5401 tttcacctaa tgaatcaatt atttcttgcc ctttagctct aatatattga tctctattac
     5461 ctatctcact cttatttaac aaaagttttt tcatgtcaaa tttaatcggc tgttttattt
     5521 ttgtaaattc gcttctacta ctaatccaat ccgagattaa tttttcaaca tgtcccagag
     5581 taaactctga tttattcgct aaatactttt tttgttgtat taaagacatc tttccccgaa
     5641 gctcaaaatt gagcctacat cgattctcta tctcttcaaa aagcatctta tcttcatcat
     5701 tcttatattc atcattcata aaaccaatcc agctcctcga ttaagataat attttaatct
     5761 catacaaaaa ctagctctca tcaaaacaac cattgttttg atttctcatg aaatttcttt
     5821 atacttttct ccgattataa attcctaacc ccttgagaaa attacgcata tatttatctc
     5881 cgcaaggctt aaaatttcgt tggccttctt ttctcaaaaa tgccccgatt tcgccttttg
     5941 atggatagat ttctgcctca gcaaaaacgt ctaaaatatc atcagtggtc atagacaagg
     6001 cgatttttaa tttttttagc aacacattgt tgatatattt gatttccttg cttttttgcg
     6061 gcgtgtctac tatcggctta tctttttgcg gaccacgcgc caagagaatc aggccattta
     6121 ggaatgcgtc aaaaacttgg ttgttgatgg ttttttcata cacattattt tctgcattat
     6181 ctttgttctt atcctgtact ttggtcagta ccgcctgagc ttcttcttta gtcagtggta
     6241 caccgcctag ctcaaaagct ttaatcaaat ccgtatcttt caaatcaatc gcataacgca
     6301 atcgcaataa cctatcattg ttattcattt gttcctccga agtatttagt ctttactttc
     6361 ttacgtactt tttgtcttgc taagattttt aggatcaatg ataaaaaccg catcacttat
     6421 gataaggcgc ccccgcattg atccggaagg cacggtagat ttgctcgaca aggatcagac
     6481 gcatcaattg atgtggatac gtcatttttc caaaagagat ctgagcattg cttcttttca
     6541 tgacggcttc gctgagtcct aaagagccgc cgataacaaa aacaaggtgg ctttttcctt
     6601 ggatacctaa ttggtcgatt tgtttagcaa aagattcact tgtaggattt ttcccttcaa
     6661 ttgctaaggc atagacgtat tcttgttctt tgattttcgc taagatccgt tctccttctt
     6721 tttcttttac ttgtctcatt tgcgcttcgc ttaaattctc cggggctttt tcgtcaggaa
     6781 cttcgatcaa ttcgattttt gcataggcat tcagccgttt gacatactca ttgatacctt
     6841 ggatcaggta tttttctttt aattttccta ctgagataat tttgatattc atgttttctc
     6901 tcctttggtc ttcatgctca ctttgtttat tataatcaat tttttcgtct atatgtttat
     6961 tttggctatt tttgttaaaa agatttcccc aacagttatg cacaacatcc acaggtttat
     7021 ccacagaaaa cagtgttatt ttaccttatt tcatcacatt cattaggcaa acatacgttt
     7081 tataagaatt tatccacttt atacacaggc tgtggatatg ttttatccct tatttttcca
     7141 atcctatccg cgtagtttta cacagtatct gtggaaaaag aaaatcaaat attttcatct
     7201 gaaaacaatg atttttccta aagtttttca taaaaagttc acagtctcaa agtagactaa
     7261 agtcaacaaa taagactata ctaacagtag ataaatgaat gtaattggag gaggaacaca
     7321 tggatagaaa aaatgtgaca ccaaagatga aaaaaagtaa aaataatagc ctctggcgta
     7381 agttaggtct ggggcttgtt ggagggatcg ttggaggact actgacagct ggcatttttt
     7441 atgcagcgat gggcactggc aacaatagtt ctactgctac aagcggcaat cagaattctg
     7501 ccggtgaaac agttgtggaa aatatcaaag tcaatgtaga ttctgatatc accaaagcgg
     7561 tagataaagt tcaagacgct gtcgtttctg ttatcaactt acaaagtcaa aaccaatcaa
     7621 gcggttttgg cggactattc gggcagcaag aagaaagtag cagctcagat gatagtaatt
     7681 tggaagctta tagtgaagga agcggcgtga tctacaaaaa agacgggaat actgcttatg
     7741 tagtcacgaa taatcacgta gtagatggcc agcaaggtct tgaagtcttg atgaaagacg
     7801 gtacgaaggt aaaagctgaa ttagttggaa cagatgctta ttcagattta gcggtgttga
     7861 agatcaattc agacaaagtc gaaacagttg cctcttttgg tgactcaagt gctctgaagg
     7921 ttggtgagcc tgcgattgcg attggttccc cactaggatc tgaatatgca aattctgtca
     7981 cttcaggaat catttcttcc ttgaaccgac aagtgacaag tacgaatgaa tcgaacgaaa
     8041 cagtcaatat caatgcgatc caaacagatg cagcaatcaa ccctggaaat tctggtggtc
     8101 ctttagttaa tatcgaagga caagttatcg gtatcaactc aagtaagatc gcaagtactt
     8161 ctgaatctac ttctaatgta agcgtagaag gaatgggatt tgctattcca agtaacgatg
     8221 tagtgaatat catcaatcaa ctggaaaaag acggaaaagt gacacgtcca gctctaggta
     8281 tcacaatggt cgacttatct gccgtttcta ctcagcaaca agaacaaatc ttgaagattc
     8341 cttcatctgt aactaacggt gtcatcgtga caaatgtcca aacagctaca ccggctgaaa
     8401 aagctggatt gaaacaatac gacgtcatta ctaagatcga tgacaaagaa gtttcttctg
     8461 gtgtagaact tcaatctgct ttgtataaga aaaaagtggg agattctgtc aaaatcactt
     8521 actatgaagg ctcgaaagaa aaaacaacta ctgttgaatt gacgatcgat caatcggcat
     8581 taaaacaaaa tcaaaatagt gaaaattaa
//
LOCUS       DARPZF010000080         8574 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.083, whole genome shotgun sequence.
ACCESSION   DARPZF010000080 DARPZF010000000
VERSION     DARPZF010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8574
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.083"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(33..236)
                     /locus_tag="SLE65_002563"
     CDS             complement(33..236)
                     /locus_tag="SLE65_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEI8449808.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(347..1531)
                     /gene="iadA"
                     /locus_tag="SLE65_002564"
     CDS             complement(347..1531)
                     /gene="iadA"
                     /locus_tag="SLE65_002564"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HEI8449809.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(1688..3427)
                     /gene="yfcC"
                     /locus_tag="SLE65_002565"
     CDS             complement(1688..3427)
                     /gene="yfcC"
                     /locus_tag="SLE65_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HEI8449810.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(4200..4814)
                     /locus_tag="SLE65_002566"
     CDS             complement(4200..4814)
                     /locus_tag="SLE65_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEI8449811.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(5420..5797)
                     /locus_tag="SLE65_002567"
     CDS             complement(5420..5797)
                     /locus_tag="SLE65_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449812.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(6097..6978)
                     /gene="galU"
                     /locus_tag="SLE65_002568"
     CDS             complement(6097..6978)
                     /gene="galU"
                     /locus_tag="SLE65_002568"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEI8449813.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(7021..8040)
                     /locus_tag="SLE65_002569"
     CDS             complement(7021..8040)
                     /locus_tag="SLE65_002569"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEI8449814.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT         2495 a         1849 c         1362 g         2868 t
ORIGIN      
        1 atttgcttga ttcaattagt aataagtggt ttttattttt tttcgtcttt tcgagaaaac
       61 ttgtctttga cttcgtcgcc taaatttcga gctttttctt tgatgtcagc acctagtgat
      121 tgtgctttcc cttctgtttc tttgctcttg tcgtctgttg ctttgccgta tgcttctttt
      181 ccttcaccga ctactttatc tttcatatct ttagaacgtc cttttaaatc tgccattgtg
      241 cttcctcctc ttagtttgtt tattgatcta ccttcagggt aacatcaaca acagatacag
      301 acaaacagaa cgctcgtttt ctaaaaaaga tagttagagc tgttgattaa aaactttttt
      361 cgaaagtccc ccatactttg acttcttttt cttggaccat tatttctcct ttagcgataa
      421 ctgtatcaat atcaagcgtt tctttatcca agatacacag atctgcatca gcaccaattt
      481 cgatttttcc ttttttatcc aatttcaata tacgtgctgg attactggtt atagctcgta
      541 aggcgatttc caaagggata ctttcttttt gcacagcttc tttgatccct actagcaatg
      601 ccttggcact tcctactcct aaccctagga aatgattgtt ttcatcaaaa taaggcaagc
      661 ttccttgtcc atctgaggtc atcgtgaaat tatctaaaga aacatcttcc tcgatcaatc
      721 gtttcagtgc tttgctgaag cgaacttcac catctgtctt ctcccaaaaa tcaggatctt
      781 cgctagcagt gaagtcaatc gtgccaccac gtttggcaaa tgccacgcaa gcttcaaata
      841 attctggtgt gcgatttgca tgagtaggca aaaattgtgt gatcggaatt tctgtttctt
      901 ctacgattcg tgtcaatagc tctagctttc tttttcctcc gcctaagtgg acattgatga
      961 tcccagcttt tccggataac atgcctccta cacgagcatc tgctactgca cgagcgaact
     1021 cttcaaaact tggctgagaa gaacggtgat cggatactgc gatttctccg attccgataa
     1081 ttttatcaat tgtcaaaaag tctttgatga tagaatctgt tactgttttt accggcaatc
     1141 ggtacgaacc ttcgtataca taagtggaga ttccttctgc ttccagacct ttcgctttgc
     1201 tgatcaacgc agtcatatct ctaccttctc cgtctgttcc caaacaaccg acaactgtcg
     1261 ttacaccagc tgtagtcaat tggctcaatg tgacttctgg cgttcgattt tgataaccgc
     1321 cttctcctcc tccacctaaa atatggaaat gacagtcaat gaaacccggg gttagtactt
     1381 ttccctcacc tgaaagttct tctacttcca ctccttcgta gccgccttct agctgttctt
     1441 ctacagccaa aatcttccca ccggcaatca gtacatccat ttttcctaag taatctggtg
     1501 caaacacttc aatttgtcga atgattttca tacatttttc ctctttcttt aagtataact
     1561 gatgatagga tcttaaaaaa taatccaaac gataggatct ttactccttt gattttaccg
     1621 taaaatgacg gttcttggag tccttatcta ctgtttggat tactttttta tttacaggtc
     1681 tccagtacta ctgcagacct attgcaatgg caatcatgat gaaaatagtt cctaaaacaa
     1741 acaggaatcc ttgcatcttg atttggaatc ttgcccattt tgcccattcg atccgtgcaa
     1801 cacctagcac accaatcaag ctggctgata cgggtgtaaa agcgtccata aaacctgaac
     1861 caagctgata agcaagaact gctacttgtc tggatacacc tactaaatct gccagtggag
     1921 ccatgattgg catagtcaaa gctgcttgtc ctgaatttga tgtaacaacc aagttgaaca
     1981 aactttggaa gatgtacatc gcccaagcac caatgacagc tggaacaccg gtcaacgccg
     2041 tcccgatccc atgcaaaatc gtattcaaag ctgaaggaac agatgcatca gatcctccca
     2101 agacaagaag aatccctttg gccataccta ctacgattgc tgtaccagct aaatcagctg
     2161 caccagattg gaaagaagaa gcgatgtcat tgactttcat tccatctaat ttgaaaagaa
     2221 cagcaatgat tccagcaact aatcccatca caaagaattg agaagcgatt tctggaatgt
     2281 aatagccttt ttgagtcacg ccccaaacga tccagacaag gacaactaac atctctaata
     2341 agatcaattt atgcccaagc atgaattttt tattttcatc agatgtcttt ttgatatgag
     2401 aacggaaata atcatctgat ttgtaagtca acgaactttc tggtttttta cggatttttt
     2461 ctgcatatat catcatataa ccagcggcta atgcagtaac aactacccac ataatcaatc
     2521 ggaatgtcgc accagacaac acggggattc cagcaatccc ttgagccacc gctacgctaa
     2581 acgggctcat ccaagaggtc gcatttccga cttgagatgc gacataagtc acggttactg
     2641 ctacgatcga gtcatatcct aacgcaatga caaatggaac catcaccatt gagaatggaa
     2701 ttacctcttc tgccatcccg aatgtagcgc caccgaatga aaaagcaaag aataatagcg
     2761 gtaaagctaa acgctccagt cccttagttt tactgataaa cgcatagata cctgcgtcga
     2821 tcgctccggt acgcataata ataccaaaag cacctccaac aacaaggatc aatgcagcga
     2881 tccctacagc agatccatac ttatctccag atactagtcc ttcaaaaaca aaatttaaga
     2941 aaccaaagcc gccaaaatca tctgttcccc atattttggc tgttttatgc aattttttag
     3001 aagtatcata gatattttcg ccgtactgat cgtaaagcac atcatctgtc aaggagattt
     3061 catctagttt ttcctgcgta agattttttt ctccgtcagc aatgactttt tccaatcctt
     3121 tttccggaac atccagtttt tcacgttctg ctggatgatc ttgcagttct tctaattgat
     3181 caaacacata cgacttatcc agctcgtaag cataacggaa ggaatcttga cgtaaaacag
     3241 tacgagtact tgtttcgcca tttgcatctt tgtattcaat atcttgcgtg ctgaactttc
     3301 ctgctggaac gacaaaagtc agtatccatg caaagatgac tacaccaaaa ataatgacat
     3361 acgtatgggg tgtcgataat ttagtgaagt cgcgtttcgg ttttcctgaa gaatttgttt
     3421 tcttcaaatt tatttcttcc tttctttttt cagtaatttt gatgaataaa aaatggataa
     3481 tcaaatgaat tatacagtaa aaatgacatt tccacatgaa taatttatta gaaaatcact
     3541 tttttctatt ttgttttttt tctcctatgt atgattattt ttttctcttt ccatttatat
     3601 taagtatttt atttctctgt ttttccttaa aattcttttt ttatttttag attagagaaa
     3661 atctcgtcct gtttttttca ttttacaatc attgaaaaat tgaatttcat tgcaaaaaaa
     3721 ataataaaca cttataaata tccattatct atccttcaat ttttgtgtat tttatttcta
     3781 ttagaaaaag gtatcctgtt ggacaatttt gttatatcag gtaaacttca ttgcaataat
     3841 gataacaaat gtactataat tactttgtaa agagttttgg ggaagactct ttcatcaacg
     3901 tgtattaaga gacaagaaag aatccatatg gattctttct tgtctctttt tccactactt
     3961 tttatttttc tgacactaca tattcttata actcatttct cataactgtg aaacaactta
     4021 taaaaataac aaactttaaa caaaacaagc ttaaaatcaa agatgatcca tcttaaaata
     4081 actaaaacaa aaaaagtagt cgttgttaat cctcattaat aatcgttttc tttttttcaa
     4141 acgctccatt tttatgtgga acattatttt tttaaggaac tttgtcaaca tgtggataac
     4201 tattttccac ttgtgtcctg gactagctgt tttgctgtaa aatacaaaac ttgctgcagc
     4261 aaaaagatcg ttgcaagaga ggctgttccg cagatcgctg gatctagatt tggcaaagtc
     4321 aagactgcat catgtaaatt ggcgtggttg tccaaaacca aatcagcaaa ttcaaataat
     4381 cgcaaaccac tgctatgttg cgatttgata cttcgtgaca aatcaaatcc agtaacaatg
     4441 attaatggat gaccattttc tttgatccac tgagctagtt cgatgattgc cgggtttctt
     4501 ccttcattcg aaagaagaag aaaaatgtct tctgatttga cagaaagctg atcaataatt
     4561 gcctgtcctg caccttctag cgtttcatag acacctccgg ctggattttc aatcaatata
     4621 cttggtacaa gatccggggt ttgatcccaa aattcaaatg ctacaccact tagtgtgcgg
     4681 ctagcatata tctgcaatct accaccttga ttaatttgtt tcgcgatcca agtgccagct
     4741 tgaagcatca gcggctcttc tatccttaat ttctcttcca attggtgata atagtcaaaa
     4801 taacataaac tcatttatct ctcccgccta gctatacttg acatgaatag aaacagctgc
     4861 ctaatctaag gaagtacata aaaaaacagt agttagacag taacacatgt ggtctttgct
     4921 gtttcaaaca caaaaaaggc attgaacgaa tacgcccaat accttgacat agcaaataaa
     4981 acaacgtgca gaccatggaa aatatctaca taggggtaga attttcaccc tagattaggt
     5041 acaataaatt aggtcgatgc actgcattga ctatggcaaa atgatcggtc agggtgtatg
     5101 tgtgtgactg gtcattccct gattcttagc gccaactaag ggtcagggag ccttttttta
     5161 ttcagctgtt tctatctgaa tttattgtaa gtaatctctt atccaagtgc aagcaagaaa
     5221 atacaaaaaa acattggtat gatttatata tatataaata acataaaaaa aggaatggct
     5281 tatcccgata caacaagcat tcctttaaaa aagattcttt tatataagtg aaaaaagctt
     5341 ttttccacca attaaataaa tctctcatct caatagttta tccattattt tatctttttt
     5401 tgcgtatacc tactaaatat taccgtcttc ttctcgttct tctactttgt tcgagagaat
     5461 ctgtactaga aaaagtagtt gtatgtctac cttttctgcc tatccgagac tttcttttca
     5521 tatatgggat ataaatgatt agatacagta cagcaaaaaa taaagcaaat acgcaagctt
     5581 cccaactacc taacgccaat tcaaccatca aggtagcaac cccaacggat gctgcatacc
     5641 agataaaaat cagaaacgtt tctttttttc tgaccatgcg aaacatgata aatagactaa
     5701 taagcaatag tggcaacaca aatatccaat tgcttccttc catcagccac ttgagtatat
     5761 caagcagcga ctgtgcaaca gcgactaatt ttcccatagt gaacacacac ctttttttat
     5821 aattaaaaaa ttcgcctttt tattctacta tgaatcttct ggcttggctt tcatttctct
     5881 tatgtaatca ttttctttta tacaacttaa aaaaaaatta aaccattagc ataatatttt
     5941 ctgaatctat tcacgaaagt ctttttctat ctttcgtttt ccacgactca actgatctag
     6001 agtcaaaaaa ctaaaacgac agttgcgcaa atgacgcaca agctgccgct ttaataacaa
     6061 atagcctttc attctcagca ggccacttat ttccagttaa ctttctgttc ttagcttttt
     6121 actcaactgg ataatatatg cacttaatga agtcccaatt tccgaatgtt gaagtccata
     6181 ttcaatattt gtcttcatat atcctaactt atcgcctacg tcgtatcttt ttcctttaaa
     6241 ctctctcgca tagaccgcct ctgtctggtt aagagtctga agtgcatccg ttagctgtat
     6301 ctcgtttcct gctcctggtt cttgagtttc taatatctca aatattttag gagtcagtag
     6361 ataacgtccg ataatggcta aattacttgg tgcttttccc atttcaggtt tttctacaaa
     6421 cccttttact ctgcaacgac ccttttcgct atctgtttta ggatcaataa ttccgtattt
     6481 agatgtttca ttttctggta cacgcatgac ggcaacagcg gaagcttgtg tttcttcata
     6541 atccatcatc aattgttgag tcaatgggat atcatctttc atcaaatcat cccccagcat
     6601 gacgacaaac ggttcatttc ctataaatgc ttttgcttga agcacggcat cccccagtcc
     6661 tcttggatga gattgacgga tgaagtgaag attgacttga gtcgtttctt caactaaagc
     6721 gagtaattct gttttttcct tttcccgcaa attgttttcc aattcgatat ttgcatcaaa
     6781 gtgatcttca atgggtcttt tttcttttcc cgttacgatc aagatgtctt cgattcccga
     6841 atccaatgct tcttccacaa taaactggat cgttggttta tccacgattg gaagcatttc
     6901 ttttgccatg gcttttgttg ccggcaaaaa acgtgttcct agcccagcgg caggaatgac
     6961 tgcttttttg accttcactt gctgttcctc ctaaacgacg attaactatt gatcatctat
     7021 ttaacgaaga gaaaattcat tctccatttt tccgtcacgt aacatgattt cttttgctgc
     7081 ttttttgata tcttctccat tatacaaaac attatagatt gtttgagtaa ttggcatctc
     7141 aacacctagc tgttgagcta gctctactgc tgcttttgtc gttgccacac cctcaacgac
     7201 cattcccatg ttttctagaa cttcttccag cttatgtccc tgtcctaaca agttaccggc
     7261 acgccaattg cgagaatgaa cacttgtaca agtaacgatc aagtccccca caccactcaa
     7321 accgataaat gtcagaggat tggcacccat cgcgacacca agacggctga tttctgccaa
     7381 tcctcgagtc atgattgctg cttttgcatc atctccgaat cctaatccat ggatagcgcc
     7441 ggcaccaatt gcaatgatat ttttcagtgc tgcaccagtt tctacgccaa tcacatcatt
     7501 atttgtataa atcctgaaat aatcattcat gaacagtttt tgtacatagg ctgctgcttt
     7561 ttgatcaata cttgcagctg taattgttgt gatatcatgt actgccactt cctcagcatg
     7621 gctaggacca gataatacaa caattgcctg tcttttttct tctggaattt cttcagccaa
     7681 aacttctgag attcgtttat gcgtatcttg ttctagtcct ttacttgcat gtataatgat
     7741 tggcttagta ttcattttac caataagttc ctgtgcgact gaacgaatcg cttttgttgg
     7801 aacaacaaat aaaatagcat ctgcgttatc cactgcttct gccaattctt tatatccgat
     7861 aatcgattct gggatcgtca aatcaggtaa aaaatgctga tttgtatgat acttattgat
     7921 ttcatcaatc tgttcaggta catttcccca aatacggaca tcatgcccgt tttctgccaa
     7981 tgtttgtgct aaagcagtgc cccaagatcc aggaccaaga actgcgattt tttgtttcat
     8041 ggatattcct ccaaataaat aattgataat ttccattata gtatacattt cttaaagttg
     8101 ggactaattt ccattgtttt taagtgtttg tttacttctt ttatcgtttt tacttgaaat
     8161 aatcaatgat atgttacaat agtctacatt ttatttttac actcgttatg ctttgcttgt
     8221 tcctaagagg aagcagtttt gacaatgtta ctaccagcat tactattagg aggttaggaa
     8281 acttctccta gtgagtattg atttaaaata cataagagac agattgaaca tttctaaatc
     8341 tgtcaggtcc tgcaacggac agattgtctc tgttgacggt tgacatagga acttttgttt
     8401 tagtcaacat tctggataca aaacgctatg taaactggcg caactcgttg tacttggact
     8461 tttactacgg atccatgcaa caactaaata gtactattgc ataacaaaaa atggttggca
     8521 cccacatgtc ccattaaaca gattataagt tgaactgtag ataatgcaaa aaat
//
LOCUS       DARPZF010000081         8493 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.084, whole genome shotgun sequence.
ACCESSION   DARPZF010000081 DARPZF010000000
VERSION     DARPZF010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.084"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..174)
                     /locus_tag="SLE65_002570"
     CDS             complement(<1..174)
                     /locus_tag="SLE65_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8449815.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFLM"
     gene            complement(594..1715)
                     /locus_tag="SLE65_002571"
     CDS             complement(594..1715)
                     /locus_tag="SLE65_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HEI8449816.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2043..3452
                     /gene="istA"
                     /locus_tag="SLE65_002572"
     CDS             2043..3452
                     /gene="istA"
                     /locus_tag="SLE65_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HEI8449817.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3449..4177
                     /gene="istB"
                     /locus_tag="SLE65_002573"
     CDS             3449..4177
                     /gene="istB"
                     /locus_tag="SLE65_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HEI8449818.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4305..5216)
                     /locus_tag="SLE65_002574"
     CDS             complement(4305..5216)
                     /locus_tag="SLE65_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEI8449819.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5233..6240)
                     /locus_tag="SLE65_002575"
     CDS             complement(5233..6240)
                     /locus_tag="SLE65_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HEI8449820.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6237..8366)
                     /locus_tag="SLE65_002576"
     CDS             complement(6237..8366)
                     /locus_tag="SLE65_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEI8449821.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSPTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8371..>8493)
                     /locus_tag="SLE65_002577"
     CDS             complement(8371..>8493)
                     /locus_tag="SLE65_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEI8449822.1"
                     /translation="NGQCLMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2598 a         1729 c         1487 g         2679 t
ORIGIN      
        1 cattaaaaag ttagtaaata attgccctct aagttccacg gtctgttcat taataacttt
       61 atatcctcgt ttttcaaaaa atggctttgc ggtaatggaa gcgtgggtag tgattttttg
      121 cataccagtt tctaaaacat ggttttccaa ttcatctgca attttagtcg caataccttt
      181 tccttgatgg ctatgttttt gtcacaactt cagtattcct gtaacaatac ggatttcagt
      241 atacaacaac agcttttgaa aagatacttg caaaaggatt aagatatcta tgacctgcta
      301 tgctcactga tgttgaaaag aatgttttat taggattgag gtaagcaaga tagtgaatat
      361 gtccggaaag cctgtaaaat aaggcttttc ggacatatgt gaagttataa aaagatagcg
      421 aaaaatctat ttagtatcac taatgttgcg aacatatcgt cagaatagtc tgacatttat
      481 ttcttgctaa aaatttcaaa aaagtcaagt gctgacgcag cggatgacta ttttccagaa
      541 aattttagta tgtattcaaa aatcaaacgt gacaacagct attaactaca tcctcatcca
      601 ggtctgtaac gtttgaacca ctcttctgcg ggctcaaaca ttaagtaatg gaaggtacgt
      661 ttcaattgaa acagcgtcgc tgtcgtattc aactcaattt ttatcacata agtgagaagc
      721 gttgcgatta aggtgaggat gacttgattt atcgcccctt gttcactatg tgaatatagt
      781 cgtttaatgg tcagattttg ttttaagtgt ttgaacaaca attcaatctg ccaacgggct
      841 tgatacatgt cggccacttc gtttggcgat acatcaaaga gattggtcac cattcgcagg
      901 attttttgtc ccttggtaag aaccgttacc aacctaaaac gctctgtcac atggttgaca
      961 ccgccgacaa gaatcacttg ttggtcactg attatcgtcc catcacgggt tgttgtatct
     1021 gctacttcaa tttgatccaa gatggtaatt tttgtattag attttgtccg tgtaacgaag
     1081 aaatagccgt cacgatttag tttgtctaac aacttgtaat caaagtagcc gcgatccacc
     1141 acatacgttg cttgcgtttt atcaacaaga acttcaaggt gattacggtc atgctcactc
     1201 gcatttgtca tcgtaaaact ttcaggatac tgattggttt tatcaagata acagagattc
     1261 aaatgtagct tgatgccaga ctttgttttc cgaaacttgg cccatggaaa ccatgctttg
     1321 ttcaacggaa tagtcgttga atcaatcaat tgtagactgg ttgtttttga gcttggctgc
     1381 tgagcagaaa ttctggcgac taattgcgta aaaatttcca tcaatacttc ttgcttgatt
     1441 tctggcgctc tacgagataa cgagctgtaa cacagggaat caatgccaag ttccttgcag
     1501 aggcgctgat ctaaaaaggc gcgatcaatc tcgcgatagc ttggcaattc ttcataaacc
     1561 gcatgaagta acactttaag cgtcgtttgg aagtctagtt ttttactgta gaaatcaaag
     1621 tcgctaatta agctttgaga gttttctgat aaaccagaaa aatttattgc agaaaaccat
     1681 ttttgaaatg aggtttttac gttatactta tccatgcgtg agtccttttt attggtcttg
     1741 gataagtcat ccgagaatag tataaaggac ttttttgcgt ttggatagct ttgtattagg
     1801 cttttgatgg gttaaaaagt ctttgcaaca ctagtaattt agtatttatg tataaattga
     1861 aagatatttt accaccactt agtcttctta aaagtgatcc aacattttgt ttgtggcaga
     1921 atttaactac acactaatgc agccgaaagt acacaactat gcagcagttt gactgcgaac
     1981 tggtttcctt ccatcataag tttgaatgac ttagtgatgg aggtacagaa aggttgttaa
     2041 ctttggatga tattaaaaca ataaaacatt tgagaaataa tcgtgatcag tcaattgatc
     2101 agataagaaa agcaatgaat atcaattggc gaacagcgaa aaaatacgcc gatagtgatc
     2161 aactattcat tacagatccc actcgaaaaa acaaatccat gatggatgat ggttggggag
     2221 aaatcatcgg tagttggcta gaagaagacc tacgtttacg cagaaaactt cgtagaacgg
     2281 ccaaagctat ccatgaacaa ttgaaacctt tgggtttccc tggctcctat cgaacagttt
     2341 gtgtatacat ttctcaatgg aaaaagcagc gttacgacga aacgaattac caagctgtcg
     2401 atcgtcttga tcatccgatc ggagaagcac aggtcgattt tggaacaatg gaagttatgc
     2461 atgaagatca catgaaagat atacaacttc ttatcatgtc atttccctat agtaatgcga
     2521 cgtccgcaag tgccatgcca gctcaaaacc aagagtgttt cctggaagca ttaaaacaac
     2581 tatttaatca atgcggcggc gttccaaaaa cgatcagaat agataactta actccagcgg
     2641 tgaaaaaaac aaaatcaaaa tttgaagaag cacaactaac cgatgaattc ttacgtttca
     2701 ccattcatta tggttgtgat gttcaagtct gtaacccacg tagtgggcat gaaaaaggac
     2761 atgtcgaaaa taaagtgggt tatgtccgat acaatttctt ctcgacttcg ccaatcatgg
     2821 actcttttga gtccctaaat aagcaacttg aagaacaatt aaaagcagat cgaaaaagga
     2881 cgcattattc aaaacatcaa ttaatcgaag atttgtggaa gaaagaaaat aaagcgttac
     2941 attctcttcc acaagaggat tacccaattt ttaaagaagt ggaagctaaa ctaaatcgtt
     3001 atcacgaaat gaaattggat caaacggtta ttcatattcc taaagcatat ggctattctc
     3061 aattgactgt tgttttgact tggaataaat tcaaagttct tacgcctcat ggagaaatat
     3121 taatgaacga atatcgcccc tatatgaaca aaaaaagatt gatcccatgg agtgacatca
     3181 tgaaacaatg gagtaataaa ttgaatgtcg ttagttattc gaggtattgg aagtacttgc
     3241 ctgcacgcct tcaaaattat ctagcgattg ataataatca cctgaaatac agacggataa
     3301 aacaattact aagtttatta gcgacctacg atatccaaca aattaatgaa caattttacg
     3361 aattagtcgt tcaagaagac gccccctctg actttgatgt gaattggtca aactatgatg
     3421 cattaacaaa aacaggaggt gtgcaaaaat gattggacag acgttagaag attattgtaa
     3481 aaagcttcga ttaagccata tcatcacgaa cataccaaga gcttctttcg aagctccaga
     3541 acaatttatt accgatttat tccgtttaga actggagacc agacagcaga tcaaattaga
     3601 acggatggaa aaattagcca aatttcctgt accaaaatcg ctaaagaact atgaatggca
     3661 cgaagatatt tttctaccat ctcatctaga taaggagacc cttgtctctc ttgattttct
     3721 aaaaaggcaa gaaaacattg tttgtgttgg ctctcctggt acagggaaaa cacatctagc
     3781 gatcgcatta gggagaaaag cctgtagtga aggtgtttca accaaatttt tccgagttaa
     3841 caatctcgta gagcaattag agaatgcatt aaaaaaacaa cagctagcca gtttcaagaa
     3901 gcgattcgaa acaacagaat taattattct tgatgaaatg gggtacttac cattgacaaa
     3961 agaaggagct gaacttctct tccaactgat ttcagattgg tatgagcaaa agagcattat
     4021 tattacctct aatttagaat tcagtcaatg gaatcgagtg tttatggatt ctcgattaac
     4081 agctgctctc gttgatcggc taatccatca cgctcacatt atcagcttca aaggcgaaag
     4141 tttcagattg aaaaattcat tatctaaatc atattgaagg aaaaaactag ttgcagcaaa
     4201 actctgcact ttcggctgca tttttttgta aaaagctatt gcacaacaca aacatttgaa
     4261 cgacgtaatt ccaaatgttg gattgctttt agataatctt ttatttattc acaattgcta
     4321 atagtccaat tttcattttt gtatagtttt aatctatact gaaaaacact tgttgttttg
     4381 gacaactcat caagatactc aacaccaaca atcacttgaa tcgctttacc cttttgtttg
     4441 taaataggat tcactaattc cacaaatttc aaattagtat taattggttg catcgcgtct
     4501 ttttcaacat aatgctctag ttctttttct gaggctgctg gataaagcct gaaaaacgtc
     4561 tctaaaaact cggtgatttc ttccgttgtc tttgaatcaa tttttgaatc actttttact
     4621 tgtcttactt tatgttttgc cttttctggc ttaccaatca tagtgggtaa actcgttaca
     4681 atatgattgc ctttttcatc ttcaaagatc atcagacgat atgcagaaga aattgattgt
     4741 gtctttttcc cttctgtaat cttttgatct accacaaatg aaacgacaaa ttcttccgag
     4801 tgtttttcaa catctagaat ttttactgat acaacctcgg aactagtggg aatatccgct
     4861 cgaaccatat cttggctcaa agcgagccct tcttctgtaa ggtactgctc aagattagtc
     4921 attctctttt caattacctc cttgttattc ttccatgaaa aatattcttt cacaaaatct
     4981 acagtaaaat tttctactcc agaggtattc actattttct ctttcacgac cactttctca
     5041 tgagttgtat gctgatcaat ggccgtgaag tttttgtaga ttccaaaagc aaggctacaa
     5101 gacaataaaa gccaaagggc aagcaccatt tttcgatgct tgcccacgga tactactcgt
     5161 tctttcttct tttttggaat cttttccttg ttacttcgct caatttttat cttcattttc
     5221 cattcctctt ttctattgtt tataccgacc agcaccaata atgtgctgtt gccaatagct
     5281 atcggtaaga ttggtccaac ccaccggatc tcctgcatga aacattctgt tctctcctgc
     5341 ataaatgccc acatgagtca cataagtacc ggcatcataa gttgaatgaa agaaaatcaa
     5401 atcgcctggt ttggcatctt ttaagtcaat atgagtcata gcatcatatt gatcctgagc
     5461 cacccgaggg agtttcaaac caactttggc ataacaccat tgagttaaac cactacaatc
     5521 aaacccagtt ccgggacttg acccaccaaa tacataagcc gttccttcat acttgaacgc
     5581 ctcgtcaaaa attccttgga ctgttttatc atcaaactgt gttgtagtta ggtactgctt
     5641 cactaataag caataaaaca tattgccata gttataccgc cacccactat tttccttaat
     5701 cgcgatggga ttgggataat cgactttttg accacccgat ttttcttttg aaaaagattc
     5761 ggctaaagca aaactatgct tctttccgtt tttcgcgaca taatccaaat acccgtcacc
     5821 atagttataa gcctgaatga tactatcttg atcgcatcct agttctttgg aacacttaac
     5881 caaagacgaa aaatagagac acacttgttt gatggatgcc tcggtactta atgaattcgg
     5941 tgataaacct gctgattcag aactttgcat gacatcttcc attgtacctc cagattcgac
     6001 ttgaataatc gccaaaagaa tcgaaacata ctctgttata tctgattctt tggcatactt
     6061 ttccaccatt gaacggtgtt tcaaaactac ttctgagaca ctactacctc caggagaagt
     6121 tccagaacta ccacttccct caccgtcctc accaaacaac aaacccacac acatcaagat
     6181 gcccacaaaa gagatggtca ggaaggttaa cgaaataata ctcaattttt ttaagttcat
     6241 cttttctcac ctggctttgg ttttgggcga gtgttctttt ttctttgtac ttgttgattg
     6301 gttcgctttg gaaaagtgaa tctctgtttc acttgttgaa aggaattgtt cttgcttagt
     6361 ggctgagtgc ttccgtttgg aatgacttct tgactagaaa gtttccgttt gatttcagga
     6421 ttcgaatgta cttgtaccct tggttttaaa gacctatttt ctggtagttc atttttctgt
     6481 ggttttatct ccttttttat cggaacattt tcccttcctt tctcatgacg attccatgct
     6541 tcgttcaata ctttgcgttt ttcatccatt tttgcgtctc ttcgttgtcg ttgtttttct
     6601 cgcaactccc ctcgatttgc tttttcttcg aaaggccctc gcttaaagtc ctctggtact
     6661 tttttcgtct tttccatgcc tttatgaagg ctgtatttca agttagttgg tgcatcggtt
     6721 acttgatttt ttgcttgttt cgctttgtcc ttcacgattt cttttgtatc gagtactttt
     6781 ccaacttttc taccaactaa atttattcgt gattctttct tcgtgcccac tggttgttct
     6841 tgttttttca gatcagaatt tagctcgtta atgcttctcg cggaatggtt ctttctattg
     6901 gacactctat tgatttttga actacctttc ccttttgtag gactggtagc tagtttccca
     6961 ccaactgctg caccgccacc aaaagcaaaa gttcgaccca catttcgatt aagctgtcgc
     7021 aattttcgat tcatcaacat ttgcggtttc cgcatgactc gccttcccat tgactgacta
     7081 tcattacttt gaaggttaaa catgctcata atgtcaccta atttgaaata gataccggca
     7141 aaggtcacaa tttgtagaaa agctaccata aagaagggat aggtggccga aatattgaaa
     7201 aacatcgtgg agatactgaa tgcagtcgta atgactaagg taactcccgc tcgcatcata
     7261 atcgtattga acaaacgaat aatcgccctt ttgcccaaac tctcatacgt cggcaacatc
     7321 gacaataaga aactaatggg cagaaacatc gcaaagataa tgaaaaggat ttgtgagaac
     7381 aacataatcc ctgtcagaag aaacacaaaa aaggaaatcc caatattaaa caacactaaa
     7441 aagaccacgg ttcctaaacg gttcatggtc ttggtaatac tgagattcgc attgtcatta
     7501 tcttcaatct ctgctttgac tgcttcttcc cgatccttac ccttattttc atccggactc
     7561 acggataaaa tcttattaac ccgaccctcg ccaatttctt ctatattgga atcatcgaat
     7621 tgtaatagta accagggttg ttgaacttga atcgaaaata aactgtctcg aatcaaatcc
     7681 acactatctt ttccctggct ttctgaatta ggtacaacaa tcttggttcc aaggctaaga
     7741 gccgcttcac taacgtctga gctaaagtca ttgatttttg taatataggt gggcgcatac
     7801 gcaatgaaag aacccgagag tagaaaaatc atcacaaaat taatgacggt tcggactgct
     7861 ttggtagttt ctcgttttaa taatccggta tacgccacat aaactcctag agctaaaatc
     7921 atcaataata ggaacccaaa gtagaatccc gaagtctgta atccattttc agtgataccg
     7981 gctaaagttt ggatattctt tccaatactt ttagccgtat ccgaaatgaa atccaacttg
     8041 taagcttctt gaaccacata gcccgtggcg tttgataaat acagacttac tgtccaaata
     8101 aaattggtaa tggcataaag accatacatc acgcttttcc ctaagccatc cccccaattc
     8161 caaggtaacc aatcccaaga actatccaca aagaaatcca gttgataatt gttcagagaa
     8221 tatttggaat aaaggtttcc ggcttcaact gtatcatcaa ccagacctgt cgcctcagct
     8281 accgtaccga ctaaactcaa tagaactgtc agagtgacga tgctaataaa aacgattccc
     8341 acaatccgaa aaagtttctt tttcatcccc tcactccatt ctctcttgaa ccggcggacg
     8401 agtgtcaaaa gcatggaaga gttcttcaaa gactggatga acttgaacca cacctactcg
     8461 cccatacaag tcttgcatca agcattgacc gtt
//
LOCUS       DARPZF010000082         8248 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.085, whole genome shotgun sequence.
ACCESSION   DARPZF010000082 DARPZF010000000
VERSION     DARPZF010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8248
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.085"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..440
                     /locus_tag="SLE65_002578"
     CDS             <1..440
                     /locus_tag="SLE65_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="topoisomerase C-terminal repeat-containing
                     protein"
                     /protein_id="HEI8449823.1"
                     /translation="TFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKAASEKQEATR
                     HLGVCPKCREQEVLLYQNVAACTSEACDFKLWTTIAKKKLTATQLKEIIQNGRTSQSV
                     RGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            456..605
                     /locus_tag="SLE65_002579"
     CDS             456..605
                     /locus_tag="SLE65_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449824.1"
                     /translation="MRNTTHKQQEIENQKAKIRLEQEKLRANKRRLQQLKNQQRIQKE
                     IELDR"
     gene            681..1274
                     /locus_tag="SLE65_002580"
     CDS             681..1274
                     /locus_tag="SLE65_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEI8449825.1"
                     /translation="MQDKLKELLAIRDGNLSMKEARKFGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEFEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            1287..2186
                     /locus_tag="SLE65_002581"
     CDS             1287..2186
                     /locus_tag="SLE65_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEI8449826.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            2189..2662
                     /gene="ssb"
                     /locus_tag="SLE65_002582"
     CDS             2189..2662
                     /gene="ssb"
                     /locus_tag="SLE65_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEI8449827.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFANQNGNR
                     EADFINCVIWRKPAETMATLAKKGGLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSTTSPSPTTFEQRDTNNGLDASQNPFGGQSIDISDDDLPF"
     gene            3028..3288
                     /locus_tag="SLE65_002583"
     CDS             3028..3288
                     /locus_tag="SLE65_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449828.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDQFTRLMGI"
     gene            3733..3939
                     /locus_tag="SLE65_002584"
     CDS             3733..3939
                     /locus_tag="SLE65_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HEI8449829.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            3939..4190
                     /locus_tag="SLE65_002585"
     CDS             3939..4190
                     /locus_tag="SLE65_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449830.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTTETPLV
                     EDAPTMLFEDLVKIAGYELHYQENLETYENEYWLTELEN"
     gene            4206..4622
                     /locus_tag="SLE65_002586"
     CDS             4206..4622
                     /locus_tag="SLE65_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449831.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFIETKKAKTVSSEWLDYFENINKYGACYIMK"
     gene            4604..4876
                     /locus_tag="SLE65_002587"
     CDS             4604..4876
                     /locus_tag="SLE65_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449832.1"
                     /translation="MLHHEVIRRIQKDFSCMEEMKYFVQNVEEQLYLESETSQTKVTV
                     SHNRLDVYKRRPESLKKGAELLRLETEKYVMNVYLEKSELVENFMD"
     gene            5043..5444
                     /gene="tnpA"
                     /locus_tag="SLE65_002588"
     CDS             5043..5444
                     /gene="tnpA"
                     /locus_tag="SLE65_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_045009167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEI8449833.1"
                     /translation="MSEIHYGRGYVYSIQYHLVWCVKYRHDVLYGQVDIDVKQFLKQI
                     ADDNNIKIIEIESDKDHIHLLIECTPQHYIPSIVKVFKGASARLLFKKHPELKQLLWG
                     GHLWNPSYFVATVSENTEEQIRKYIQNQKKK"
     gene            5456..6601
                     /locus_tag="SLE65_002589"
     CDS             5456..6601
                     /locus_tag="SLE65_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8449834.1"
                     /translation="MLQHRAYKFRIYPNQEQEILMTKTIGCSRFVYNYFLNLWNHEYT
                     TTGKGLSYNSCSAMLPQMKRNAETIWLKEVDSIAIQSSLKNLSDAFSRFFKKQNKRPQ
                     FKSKKHPIQSYTTKNVNNSIEIRNNFVKLPKLGFVKFAKSQEPKGRILNATIRKNSSG
                     KFFVSILCEEEIVEFPKSNSAIGIDLGITDFAILSDGQKIDNNKFTSKMAKKLKREQR
                     KLSKRALLAKKKGVNLFEAKNYQKQKRKVARLHEKVMNQRNDFLNKLSTEIIKNHDII
                     CIEDLNTKGMLRNHKLAKSISDVSWSSFVTKLQYKANWYGRKIIKVDKWFPSSQICSN
                     CGHKDGKKSLEIREWTCPVCHAHHDRDINASINILTEGLRLHVMGLA"
     gene            6839..7102
                     /locus_tag="SLE65_002590"
     CDS             6839..7102
                     /locus_tag="SLE65_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HEI8449835.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            7096..7446
                     /locus_tag="SLE65_002591"
     CDS             7096..7446
                     /locus_tag="SLE65_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HEI8449836.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(7470..8084)
                     /locus_tag="SLE65_002592"
     CDS             complement(7470..8084)
                     /locus_tag="SLE65_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8449837.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
BASE COUNT         3024 a         1331 c         1573 g         2320 t
ORIGIN      
        1 ctactttctt agctaatatc caaaaatttg tctctcactt gttggaagtc gtaccgggac
       61 aaatccagtc aacagatttt ggatcaacgt tacaagaggt gaaagcagcc agtgaaaaac
      121 aggaagcaac gcgtcattta ggtgtttgtc caaaatgtcg ggaacaagaa gtcttgcttt
      181 atcaaaatgt ggcggcatgt acgtctgaag cctgtgattt taaattatgg acaacgattg
      241 ccaaaaagaa actcacagcc acacaactga aagagatcat tcaaaacggc cgaacaagcc
      301 aatcagtcag aggactaaaa ggtcagaaag gttcgtttga agcaacgatc gttttaaaag
      361 aagactttac aacaggcttt gaattttctg aaaagaaaaa aacgaactat aagaaaagaa
      421 cacgccgcac tacaaaataa tgaaggggtt atcctatgcg aaatacaaca cacaaacaac
      481 aagaaatcga aaatcaaaaa gcaaaaattc gtttagaaca agagaaatta cgtgcaaata
      541 aaagaagact gcaacaatta aagaaccagc agcgcattca aaaagaaatc gaattagatc
      601 gatagacgtt aatcttgtta caaataaact actatgatat atttgatgta gtgtatttgt
      661 aacgaaggga ggggaagtaa atgcaagata aactgaaaga attgttggct attcgcgatg
      721 gaaatttatc tatgaaggaa gccaggaaat ttggaatcgc agcaaccact gtacaaagat
      781 tggtgaatca aggaaaattg atcaaagttg atcgtggtta ttatgtagag gatggtcatg
      841 gaatagatga tttattttgg cttcagcaac gattttccag gggaatcttc tctcatgaaa
      901 cgactttaga tatttaccag ctttctacga atatgccgaa attcattcac ttaacttttc
      961 cccatggcta taacgttgat cgttcaatta caaaagagca gcagttacaa tttcatttcg
     1021 tgaagaaaga agtttatgaa ctaggaaaag tagagggaac ttcctttcaa ggaaatccta
     1081 ttactatgta tgataaagag cgtacacttt gtgatatttg gaatccgaga tatgaatttg
     1141 aatatgaaat gaaattagaa gcattaaaag agtacatgga agacccattg agagatccaa
     1201 gtaaattaag agattacatg acaaaactac atgtagaaaa agaaatgaaa taccacatgc
     1261 aaagcttata ttgatggagg aaaaagatga caccgacaca atttgcagca aaaacaagaa
     1321 atttagcaaa gagtacagga ttaaatgcac agttagtgca acggcatttt atgatggatc
     1381 gtctaattga acaaatttct gaatcaaagt acaaaaatga cttcattttg aaaggcggct
     1441 ttttattagg atcaaaatat ggaatcgata gaaggacaac aattgatatc gatacgacat
     1501 ttagaaatag caaattaact gaagaaaaat tgaagagcat ttttaatgat ttaactagaa
     1561 aacccacaaa agaaggcatt gttttctcta ttcaaggaat gaaggaaaca agagaagccg
     1621 atttttatcc tggatttcaa attaaattgg tggctaattt agagaaagta cgtgtaccgt
     1681 ttaaaatgga cgtgacaaca ggagattcta tttatcctga agtagataca cactatcacc
     1741 aattaatgtt tgaagataaa aaagtggaga ttccagctta tccaacagaa caaattattg
     1801 cagaaaagct aagtgctacg ttcagctttg gcacagataa ttcgagagca aaagattact
     1861 acgacttatt taccattccg aaactagaaa atatcgatac gaaagagtta tacaaaagtg
     1921 ttcgaaatac atttacaaaa cgtggggata caaaaccgtt gtccttttat tatgaaagag
     1981 aaatggataa gatcagagga aatgactatt tggaaaagca gtgggaaaaa tatcgctcag
     2041 ttaacacgtt tgcgaattcc atttcattta cagatacagt caacgaaatt gatcacctaa
     2101 tgaaaagtgt gatcaaaatt gaaaatcaag aaagaaaacg gcagtttaaa agatcacaac
     2161 aaatgaatca agaaatggag agataaagat gattaataat gtgacattag taggacgctt
     2221 aaccaaagat cccgatttac gttatactgc aagtggcaca gcagtagcga cttttaccct
     2281 agccgtcaac cgaaatttcg cgaatcaaaa cggcaatcga gaagccgatt ttattaactg
     2341 cgtgatttgg cgcaaaccag cagaaacaat ggcgacatta gctaaaaaag gcggcttgat
     2401 cggtgttgtc ggacggattc aaacacgaac ttatgacaac cagcaaggac aacgtgtgta
     2461 tgtgactgaa gttgtagcag ataactttca actattagaa agtaaagcag cgacagagag
     2521 ccgtgcgcac gctgatcaat caaccaccag tccaagcccc actacctttg aacaacggga
     2581 tacaaacaat ggattggacg cttcacaaaa tccatttggt ggacaatcaa tcgatattag
     2641 cgatgatgat ctaccattct aagtagcatt ttctattggt tgcatttgct acggtttatg
     2701 ttataattta gtcaacaaaa agaattttca atctataacc aaaaaccact agctggcggg
     2761 ctagtggttt tcttttacgt ttctattata agaattaacg ggtaggctta ctgtctttct
     2821 tggcaaattt acaatcaagc catttgcaga tatagtgcgc ggctacttct gccatgattg
     2881 caaaaacaaa atcaaaaaga attttcaaac ctataacctc ctccccttgc cagattaggc
     2941 cggggtagca gacagcaaga ctattatagc ataattgaaa tattcaaatg attggatttt
     3001 tgctataatt ttagcgaggt gattgtgatg aacaaatatg ttggtttgct tgataaaatc
     3061 cgagtaataa aaacgcaacc gttattggtt cgctttactt tacaaacgat tcatgaatcg
     3121 attaattgtg tagttgcaga tattgaaatt atcgataaat tgctaattat ggatgatgga
     3181 aaatacaata ttgccgtcac aggtcacttc aataaacgaa accagctagt tattgctagc
     3241 atgtatgtta gaaatcccga tcagtttacg cgattgatgg gcatataaaa aaagaagagt
     3301 tgcaatccta atgtaggact gcagctcttt ttgttttaca tagaaacaag aaaaatgaaa
     3361 aggccttttt aggaaggcgc gagcgccttc tcaattgaaa aacctctctc actccaaccg
     3421 ccaccgccgt tcgagaagaa aggaagtgaa cgttgcacgt tcactaagat aaagggtctt
     3481 gcaaagcaag acaaaataga aaaaacttcc tctcaccaaa aggttcgttc ctgttcgtta
     3541 tctctttatt gatttgccag accggcaaca agttgccttt tatcaccaaa aagcgacaag
     3601 gacaagggta aatggcacgc tgcgcgccct tgtccttgtc gcttttcgtt gattcattct
     3661 ggccaacaaa tcaataaaga aagaactaac gaaaggaagt aaaacctttc ctaagaggag
     3721 gcagaatcaa tcatgcgaaa gaaatttgat tattggggtg ttcccttcag cgaattattc
     3781 ccaaactatc atgcaccaca tactgtcgaa tgcgattgtg gagaaagagc gaaatgtatc
     3841 aaaagctatc gtttgtatca atgtccaaca tgcgggaaaa aatatacctt gtcttatggc
     3901 gattatattt tgattgatga gaaaggaaag aaacgttgat gaaaacacaa cacaaattat
     3961 tgactgtaaa agaagtcgtt caaattttgg tggacaaaga agtcatttct gaaaaagtag
     4021 cagaagcttt acttattccg cggtactgga cgacagaaac ccctttagta gaggatgcac
     4081 cgactatgct atttgaagac ctagtgaaga ttgcaggata tgaactgcat tatcaagaaa
     4141 acttggaaac ttatgaaaac gaatattggt taaccgaatt agagaactaa aaaggagaaa
     4201 aaaatatggc tcaaaattac tatgacgaat ttgtcaaatt acctttggat aaaatggcac
     4261 aaaaaatgga ggatatgaca ttcctataca atgagacacg tgttccaaaa aaacattata
     4321 aggaaagatt gtcggtagct gtggaagaaa tgattgaatc aggtgtcgaa atgaatctca
     4381 ttgcgacgta ttatcgaaca ctggaagaac tgaaaaagca aaatgcaaaa tggtttttcc
     4441 aagccttact atgcttggaa gtaggcgtca aaccaagcac aatcaaacct tctgaatacc
     4501 aagctttaga actaacgtat gcgaaattta tcgaaacgaa aaaagctaag actgtttcaa
     4561 gtgaatggtt agattatttt gaaaatatca ataagtatgg cgcatgttac atcatgaagt
     4621 aatcagacgg attcaaaaag actttagttg tatggaagaa atgaagtact ttgttcaaaa
     4681 tgttgaagaa cagttatatt tggaaagcga aacgagtcaa acaaaggtca cagtcagcca
     4741 taatcgttta gatgtgtata aacgtcgtcc tgaatcatta aaaaaaggag cggagcttct
     4801 acgactagaa acagaaaaat acgtcatgaa tgtttaccta gaaaaaagtg agttggtcga
     4861 aaattttatg gactagccga gaacacccgt gattttaatc atgggatgaa tcggattcag
     4921 ttgtgaccta gctttagcta ggttaaacaa ctgacaaata taaactaaat aatagtgaaa
     4981 tgtcttgcaa taattgattt tgtagaaata catatattaa aataattgcg aggtgttttt
     5041 gtatgtcaga aattcattat ggacggggtt atgtctattc tattcaatat catcttgttt
     5101 ggtgtgtaaa atatcgacat gatgttttgt atggtcaggt agatattgat gtcaaacagt
     5161 ttttgaaaca aattgctgat gataataata taaaaattat agaaatagaa tcagataaag
     5221 accatattca tttactcatt gaatgcaccc cacaacacta tattcctagt attgttaaag
     5281 tatttaaagg cgcatccgct agactgctgt ttaaaaaaca tcctgaactt aaacaactcc
     5341 tttggggtgg acatctttgg aatccaagct actttgtagc tactgttagc gaaaatacag
     5401 aagaacaaat tagaaaatat atacaaaatc agaaaaagaa atgaggtgaa tccgtatgct
     5461 acaacatagg gcttataaat ttagaatcta tcctaatcaa gaacaagaaa tattaatgac
     5521 taaaactatt ggctgttcaa gatttgtcta taattatttt ttgaatttgt ggaatcatga
     5581 atatacgact actggaaaag gattatctta taattcttgt tctgccatgc ttccacaaat
     5641 gaaaagaaat gcagagacaa tttggttaaa agaagttgac agtattgcga ttcaatcctc
     5701 attgaaaaat ctttctgatg ctttttctcg cttctttaaa aagcaaaata aacgaccaca
     5761 atttaaaagt aaaaaacatc ctatacaaag ttatacaact aaaaatgtga ataatagtat
     5821 cgaaattaga aacaatttcg taaaactacc taagttagga tttgttaaat ttgcgaaaag
     5881 tcaagagccc aaagggcgaa tcttaaatgc tacgattcga aaaaattcga gtggtaaatt
     5941 ttttgtttcc atcctgtgtg aagaagaaat agttgagttt cctaaatcta attccgctat
     6001 tggaatcgac cttggtataa ctgattttgc aatcctttct gatggtcaaa agattgataa
     6061 caataaattc acgtcaaaaa tggcaaaaaa actcaaacgt gaacaacgta agttgtcaaa
     6121 acgtgcatta ctagctaaaa agaaaggcgt caatctcttt gaagctaaaa attatcaaaa
     6181 acaaaaacga aaagtagcac gactacatga aaaagtaatg aatcaacgca atgacttttt
     6241 aaacaagttg agcacagaga ttatcaaaaa ccacgatatt atctgtatag aagacttaaa
     6301 tacaaaaggt atgttgcgta atcataaact agcaaaaagc atttctgatg tgtcttggtc
     6361 tagttttgtg actaagttac aatacaaagc taactggtac ggtcggaaaa tcatcaaagt
     6421 agataaatgg tttccatcta gtcaaatctg ttcaaattgt ggacacaaag acggcaagaa
     6481 atctctagaa attcgagaat ggacttgtcc tgtttgtcat gctcatcatg accgagatat
     6541 caatgctagt atcaatattt tgaccgaagg tctaagatta catgtcatgg gattagctta
     6601 gatccaatca tcaaaaaccg taggaactac ggggatagct tggtaaataa gagaaaccgc
     6661 tgtgagtaaa gaaatacgct tgcaagtatg ctctattccc aagaatctcg tgactttagt
     6721 catgagaggt tcaaggattc atggaatgtt aatctaattt aatagaaaag gataattaag
     6781 tatatacgtt ttttcttatg tatgttatac tatgtatata cagaaagagg tgtctactat
     6841 ggaaatgtta cctataaaaa aatggggaaa tagtaatggc cttagattgc caaagtatat
     6901 tatggaatat cttggaattc atacagaaga caaagtgaag ataatacaag aagaagtaaa
     6961 cggtcagaag cggctaatta tcgaagcggc taatatagaa aatgaattaa caattgaaca
     7021 gttatttgaa aattacactg atgaaagaaa tcatgtgacg attcaaaatt taggtgaagc
     7081 agtaggtaat gaaaaatggt gagaaaacct agacaaggcg atattctatt attgaataca
     7141 gcacctcgat ctggacacga acagacaggt aaaagacctt atattgtttt aagtcatgat
     7201 attattgcgg attatagtaa cgttgttaca gttgctccaa tttctagtac aactagaaac
     7261 tatccgctat atgtaaatat aaactcagaa tatgaaatga agacaacagg aaaagtatta
     7321 ttagatcaac taacgacaat tgattatgaa gccagagagt gtattttttt ggaaaaagcg
     7381 catgatagtt tagttgagga gttattgatg aaagttagaa cagtttttca aaaagtaagc
     7441 aaataaaata gaaacagcag catgatcaac tattcgtgat tgaccatgct gtcttttttt
     7501 attctatata cggtttgtct cgtaacattg tagtcttttg caatcttagc gatcgcaaca
     7561 ccttttttta gatcctcaac gatgttttta taaacaagac gacgttgggg atcttttgca
     7621 ttggcactgt atagcttagg acgtccttta taaacaccgt tcgcttttgc aatcttaatg
     7681 ccttgtgcct gacgtcgttt agattcggta cgttcttgtt cagcgatcat ggccaaaatt
     7741 tgaatgatca aatctttaat gaatttatcc aggagaggat tgccaattgc ttcggccatg
     7801 atcggtagac ttgtgatgat cagctgcaca tttttcttct tcaagtaatt gactgaagcg
     7861 atgatctcgt cgtaatttct tccaagtcga tcaatagctt ccacaataaa aatatcttga
     7921 tctcggacga aatccagtgc ttcttgaaaa acaggtcgat gagtaatcgt tgcgccagat
     7981 tgtttctcaa tgaaaattct ctctgcaccg aattttttca tttcttcaat ctgccgttgt
     8041 tcattttgat cgatggatga gacacgtatg tatgcaactc tcaaaatttt tacctacttt
     8101 ctgcaactat ttaaaaaaca ccctaatcat acacgagaaa accagatttt tcaatgtcgc
     8161 ggtcgtgtct agttagggta taccttatat agacaaaaac taatgatgga ggaaatagta
     8221 tgtgtcactt ttctttttaa atggcaat
//
LOCUS       DARPZF010000083         7815 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.087, whole genome shotgun sequence.
ACCESSION   DARPZF010000083 DARPZF010000000
VERSION     DARPZF010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.087"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..1158
                     /locus_tag="SLE65_002593"
     CDS             <1..1158
                     /locus_tag="SLE65_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HEI8449838.1"
                     /translation="PRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDT
                     PYITEGEYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMT
                     AAAFEQLSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGW
                     KKLFGKESDRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAG
                     KTVDSEEAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVE
                     KEPLLTSAEMTAKWESYLLKIGEQKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGST
                     LQEVKAASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKRSEGFI"
     gene            1274..1423
                     /locus_tag="SLE65_002594"
     CDS             1274..1423
                     /locus_tag="SLE65_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449839.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            1504..2100
                     /locus_tag="SLE65_002595"
     CDS             1504..2100
                     /locus_tag="SLE65_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEI8449840.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPEKTLCDIWNPWYNVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            2113..3012
                     /locus_tag="SLE65_002596"
     CDS             2113..3012
                     /locus_tag="SLE65_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEI8449841.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNDIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            3015..3146
                     /gene="ssb"
                     /locus_tag="SLE65_002597"
     CDS             3015..3146
                     /gene="ssb"
                     /locus_tag="SLE65_002597"
                     /inference="COORDINATES: protein motif:HMM:TIGR00621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEI8449842.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGN"
     gene            3168..3500
                     /gene="ssb"
                     /locus_tag="SLE65_002598"
     CDS             3168..3500
                     /gene="ssb"
                     /locus_tag="SLE65_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEI8449843.1"
                     /translation="MIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEV
                     VADNFQLLESKAATESRAHADQSSTSPSTATFEQRNTATPNNNGLNASQNPFGGQSID
                     ISDDDLPF"
     gene            3545..3778
                     /locus_tag="SLE65_002599"
     CDS             3545..3778
                     /locus_tag="SLE65_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449844.1"
                     /translation="MDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVFVYLVCSYL
                     LKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(3937..4059)
                     /locus_tag="SLE65_002600"
     CDS             complement(3937..4059)
                     /locus_tag="SLE65_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEI8449845.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            4249..4473
                     /locus_tag="SLE65_002601"
     CDS             4249..4473
                     /locus_tag="SLE65_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449846.1"
                     /translation="MIKTQPLLVRFTLRTSHEPINCVVANIEIADKLLILEEGKYTIS
                     VTGHFNKRKQLVIESMQIRNPDHFTRSMSI"
     gene            4916..5122
                     /locus_tag="SLE65_002602"
     CDS             4916..5122
                     /locus_tag="SLE65_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HEI8449847.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            5122..5373
                     /locus_tag="SLE65_002603"
     CDS             5122..5373
                     /locus_tag="SLE65_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449848.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEVLLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENLETYENEYWLTKLEN"
     gene            5389..5544
                     /locus_tag="SLE65_002604"
     CDS             5389..5544
                     /locus_tag="SLE65_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449849.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIE"
     gene            5554..5826
                     /locus_tag="SLE65_002605"
     CDS             5554..5826
                     /locus_tag="SLE65_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449850.1"
                     /translation="MNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQ
                     ALELTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            6271..6450
                     /locus_tag="SLE65_002606"
     CDS             6271..6450
                     /locus_tag="SLE65_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449851.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            6509..6865
                     /locus_tag="SLE65_002607"
     CDS             6509..6865
                     /locus_tag="SLE65_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449852.1"
                     /translation="MLKTKKNSYKLKLSILSIICLLGMIISGHLYRVAYTQFIEYKVH
                     SLGLAGDRYVEYVHYSLKCSSYILLWLIFSLFELLNLIAISSYHLDKLNTKSSRYNEV
                     FKENVKLESDLNKLKK"
BASE COUNT         2816 a         1286 c         1571 g         2142 t
ORIGIN      
        1 ccacgtcttt tttctctatc cagccttcaa tctaaaatga atcagctcat gaaagctagt
       61 gccaaagata ctttggaagc catgcaaggg ttgtatgaag ggaaatatct aagctaccca
      121 cgaacagata ccccttatat tacagaaggg gagtatgcgt atctgttgga tcacttagac
      181 gaatacaaac actttttaaa ggccgaagcc attcctactc ctattcatac accgaatagt
      241 cgatatgtga ataataagaa agtccaggaa cattacgcga tcattcctac aaagacggtc
      301 atgacggcag cggcttttga acaattaagt ccactgcagc aggctattta tgaacaagtg
      361 ttaaaaacaa cggtggccat gtttgcggaa aagtatacct atgaagaaac aacgatcttg
      421 acgcaagttc agcagcttca gctaaagaca gtcggaaaag taccagtaga tctaggttgg
      481 aaaaagctgt ttggcaaaga gagcgacaga aaagaaaagg aagaagaacc gctacttcct
      541 aaagtgacaa aaggagaagc ggtgacggta gatctacaag tccttgaaaa agaaacgaag
      601 ccaccacaac cttataccga aggtacgttg atcacagcga tgaaaacagc tggaaaaacc
      661 gtggatagcg aagaagcaca atccatattg aaagaagtag aaggaatcgg tacagaagca
      721 acacgagcaa atattattga aactttgaaa caaaaggaat atatcaaggt agaaaaaaat
      781 aagcttgtgg tgacaaataa agggatttta ctttgccaag ccgtggaaaa agagccgctg
      841 ctaacaagtg ccgaaatgac cgccaaatgg gaaagttact tattaaagat tggtgagcag
      901 aaaggaacac aaaccacttt tctagccaat atccaaaaat ttgtctctca cttattggaa
      961 gtcgtaccag ggcaaatcca atccactgat tttggatcga cgttacaaga agtgaaagca
     1021 gccagtgaaa agcaagaagc cgcgcgtcat ttaggaattt gtccaaaatg ccaggaacaa
     1081 gaagtcttac tctatcaaaa ggtggcagct tgtacgtctg aagcctgtga ttttaaaagg
     1141 tcagaagggt tcatttgaag caacgattgt tttaaaagaa gacttcacta caggctttga
     1201 attttctgaa aagaaaaaaa cgaacttcaa gaaaagaaca cgccgcactg caaaataatg
     1261 gagggttaat cttatgcgta ataccacaca caaacaacaa gaaatcgaaa atcaaaaagc
     1321 caaaattcgt tcagaacagg aaaaaatgcg tgccagcaaa cgaagactgc agcaattgaa
     1381 gaaccagcag aggattcaaa aagaaatcga attagatcga taaaatcttc ctaactattg
     1441 tatacgtata aacttatgtt atactgtttt tataagttta tacgtataca aaggagggag
     1501 aaaatgacaa aagcaatggt atacaagctg ctagaagaat ttaatggaac tttggctttg
     1561 aaggatgcca aaaaagcggg catttctcct gtaacgatca aacgtatggt agatcgaggg
     1621 gagctggatc gagagtatcc aggttttttc accttacctg gtcaatttcc tgatgaattg
     1681 tttatggcgc aaaaaaaata tgaacgcggc attatttcac atattaccgc gttagatttg
     1741 tatgatttaa cagatatgat ccctagacag atcgatctga ctgtacctta cggttatcac
     1801 gtttctgaaa aaggattgaa ggaattcgca gttgagctac actatacaaa agcggaatgg
     1861 tatgaattag gtaagattga aataaaaagt cgctatggga atcctattat agcttatgat
     1921 ccagaaaaaa ccttgtgtga catttggaat ccctggtata acgttgagga tgaaatcaaa
     1981 gtaaaagcaa tcaaaaacta catggagtcg gacagaaaaa atcttagaaa attgaatgag
     2041 tatcgacgaa ttttgcctac agataaaacg atgcgctctt atattatggc tttaaattaa
     2101 aggagaatac acatgacacc tacgcaatta aaagcaaaag tgaagaatat ttctagagaa
     2161 aaagaagttg atccgcagct tgttttaaga cattttatga tggaaaaatt cttggaaaaa
     2221 atctcagagt ctccttatcg tgaaaatttt gtgttaaaag gcggcttctt aattggctca
     2281 aagtatggca ttgaaaatcg aacaactaaa gacattgata cgactttacg ggaaatgaaa
     2341 gtaaccaaag aaacattgac aacggttcta aacgatattt tttcaacgcc gacgaaagaa
     2401 ggcattcaat ttgagattca aggaatgaaa gaaacgaggg aagctgatta ttatccaggg
     2461 tttagcttac gtgtactggc acatttggaa aacatgcggc cagattttaa ggtagatgtt
     2521 actacaggtg actcgatcta tcctgcgacg atcactcaca gtcataaatt gatgtttgag
     2581 gatcgaacga ttcctttgga atcctatcct acagaacaaa ttattgctga aaaattaagt
     2641 gcaacctttg attttttaac agataattcg agaggaaaag atttttatga tctctatact
     2701 attcctaaaa tggagaagat cgatgagaag accttgaaag atagtgtgag aaatacattt
     2761 acacgtcgag gaaaaactga tccgttaaag atatactatg aaaaggatat ggatgtactg
     2821 aaaaatagtc acgagctaaa agatacctgg aagaaatatc aaaaaagcaa tccttatgct
     2881 gcgtcgatca cgtacgatga gacaatggat tcgattagta atttgatgga aaaagtgatt
     2941 cacgtcgaag aaaaagagcg aaaactagct tatcaaagac accaacagat gaatagagaa
     3001 atggagagat aaagatgatt aataatgtga cattagtagg acgcttaacc aaagatcctg
     3061 atttacgtta taccgcaagt ggtactgcag tagcgacttt taccctagcc gtcaaccgaa
     3121 atttcacgaa tcaaaacggc aattgagaag ccgattttat taactgcgtg atttggcgca
     3181 aaccagcaga aacaatggcg acattagcta aaaaaggtag cttgattggt gtagttgggc
     3241 ggattcaaac gcggacttac gacaaccagc aaggacaacg tgtatatgtg actgaagttg
     3301 tagcagataa ctttcaacta ttagaaagta aagcagcgac agagagccgt gcgcacgctg
     3361 atcaatcgtc caccagtcca agcaccgcca cctttgaaca acggaataca gcgacgccta
     3421 acaacaatgg attgaacgct tcacagaatc catttggtgg acaatcaatc gatattagcg
     3481 atgatgatct accgttttag tttgagaaag aaggagtaag catggcaaaa aaattagtct
     3541 gacgatggat ctattgatac ccgtaattgc atttatagac gggatttctt tgggcgtcac
     3601 tgaaaatcct ttggtaaata gaattgcgaa aggatcacta tttcttgtat tcgtgtatct
     3661 tgtctgttct tatcttttaa aaagagcagg aaaggataat tccttttggc gattgactaa
     3721 agtcacagta gcagcgacag ctgttatact tacggctatt ctaccgcttt atatgtagag
     3781 ttaacgggaa atcgttgaac ttcttgcgaa atattgctat aatgaacatg aaaaagagga
     3841 gttgcgctaa caacccctca ttaacagcac cgattaaaga acggtggcag aatattagtt
     3901 atttggaaat aaccgctgac ctgctaaagt agacggttat ttctttttgt catttttaag
     3961 catatttaca atcaaactaa tcaaagcaat ggtaaacata ccaaaaccaa gaatggtttg
     4021 aattgtctca tatgcggaca aaaggcttac tcctttcata gattttagca cttacattca
     4081 taagcaccac cacctttcca gaagtcgcca ccgtcttcaa actttactgt cttgactatt
     4141 atagcatatc taaaatcgaa taaaaattct caattttagc tgtttttgct ataattttag
     4201 cgaggtgatc gtgatggaac aatatattgg tttactcgat aaattagggt gatcaagaca
     4261 cagccattgc ttgtgcgatt tacattacgc acgagtcatg aaccaatcaa ttgtgtagtg
     4321 gccaatatag aaatagcgga taaattgctg attttggaag aaggcaagta tactatttca
     4381 gtgacaggtc acttcaataa acgaaagcaa ctagtcattg aatcaatgca aattagaaac
     4441 cctgatcatt ttacgcgatc gatgagcata taaaagaaga gctgcagtcc taaatgagga
     4501 ttgtagctct ttttgtttta catagaaaca gtaaaaatga aaaggcctgt ttaggaaggc
     4561 acaagcgcct tctcaattga aagacctttc tctcactcca accgccaccg ccgttcgaga
     4621 agaaaggaag tgaacgctac gcgttcacta agataaaggg tcttgcatag caagacaaaa
     4681 tagaaaaaat ttcctctcac caaaaggttc gctcctgttc gttatctctt tattgatttg
     4741 tcagaccggc aacaagttgc cttttatcac caaaaagcga caaggacaag ggtaaatggc
     4801 acgctgcgcg cccttgtctt gtcgcttttc gttgattcat tctggccaac aaatcaataa
     4861 agaaagaact aacgaaagga agtaaaacct ttcctaagag gaggcagaat caatcatgcg
     4921 aaagaaattt gattattggg gtgttccctt cagcgaatta ttcccaaact atcatgcacc
     4981 acatactgtc gaatgcgatt gtggagaaag agcgaaatgt atcaaaagct attgtttgta
     5041 tcaatgtcca acatgcggga aaaaatatac cttgtcttat ggcgattata ttttaattga
     5101 tgagaaagga aagaaacgct gatgaaaaca caacacaaat tattgactgt aaaagaagtc
     5161 gttcaaattt tggtggacaa agaagtcatt tctgaaaaag tagcagaagt tttacttatt
     5221 ccgcggtact ggacgataga aaccccttta gtagaggatg caccgactat gctatttgaa
     5281 gacctagtga agattgcagg atatgaactg cattatcaag aaaacttgga aacttatgaa
     5341 aacgaatatt ggttaaccaa attagagaac taaaaaggag aaaaaaatat ggctcaaaat
     5401 tactatgacg aatttgtcaa attacctttg gataaaatgg cacaaaaaat ggaggatatg
     5461 acgttcctat acaacgaaac acgtgttcca aaaaaacatt ataaagaaaa attgtcggta
     5521 gctgtggaag aaatgattga ataaggtgtc gaaatgaatc ttattgcgac gtactatcga
     5581 acactggaag aactgaaaaa gcaaaatgca aaatggtttt tccaagcctt actatgcttg
     5641 gaagtaggtg tcaaaccaag cactattaaa ccttctgaat accaagcttt agaactaacg
     5701 tatgcgaaat ttatcgaaac gaaaaaagcc aagactgttt caagtgaatg gttagattat
     5761 tttgaaaata tcaataagta tggcgcatat tacaccatga aaaaggaaga caacgaaaat
     5821 gaataaggtg atttatcaac taacaacgga ttccatatca acgatttgaa agaaaaaaag
     5881 gtcaataatc atttataccg aaaagtgaga atgtgtgaaa caaggacaaa aaaagcctag
     5941 taactaagga aatggttctt atttcgcacc aatcgctcca accgcccccg ccgcttaggt
     6001 ggtgcgaaat aaacgggcaa agcccgataa cttaagagaa agaaggtgat ccatttgaac
     6061 aagattattc ccttattgtt agtactgttt gttggcgaaa tacttatgcg agatagtgca
     6121 gctgtacagt taaacctcgc tgtatttttg gtaatactgg tgttttgttt gatcttttgg
     6181 cggtttgtat tagtcctcgt gagtctacta ttcaagatga ttgcagccat atttttcata
     6241 gggttatttc gatgaaagga gtgagtacca atgccaattg caataggaaa taaacggtta
     6301 cccgtgacat tagatgaaaa gagacaaaaa gaattgcagc aactaaagca gaagtatggc
     6361 aaaagtgaat ctaagattat gtgtattgcg ttagatctat tgatcgcgca agaaaaagca
     6421 ggatttgatg taccagcgct aaaaaagtga cgtcactttt taatttgatc tatataagtg
     6481 atatcacttt taccaaggag ggaattaaat gttaaaaact aaaaagaatt cgtacaaatt
     6541 aaagcttagt atactatcta ttatttgtct tttaggcatg ataattagtg gtcatttgta
     6601 tagagtggca tatacgcagt ttattgagta caaggttcac tctttaggat tagctgggga
     6661 tcgatacgtt gaatatgtcc attattcatt aaaatgttct tcatatattc ttctttggct
     6721 tattttttca ttgtttgaat tgctaaattt aatagcaata tcttcatatc acttagataa
     6781 gctaaatacc aaatctagcc gttataacga agtgtttaag gaaaatgtga agttagaaag
     6841 tgacttaaac aagctaaaaa aataaaaaga agaaaacata agttaactaa aattatttta
     6901 ttaagaatga tggaatataa ggataaggtt accaacataa cgatcattac ttctctgata
     6961 tgctatggac ttctatcaat cagtattttg tctatagatt atggagtaac tatactgcaa
     7021 gccttagttt tggctatgcc tatgtatcta tctttgttta tcatgcatga aatatataag
     7081 ctatttgttt tatcaaaaaa tgtagaaata cgggtaaata ttttggtgaa tagttatcaa
     7141 aaagaactca aagaaagaag acggtggcgg tatttattga aaggatgaaa aagtaggatt
     7201 tgacatactg gtattcagaa agtgccgtca cttttaaaac aatggaaaag gtggagataa
     7261 gatgaagaaa aaacaaacta aactatcatt agcagatatt taacacagtt aaccgcaact
     7321 gaagatggtg ttgttgaatt tgaacaatct gaaattgcgg tagtagatga tcgttacctt
     7381 aaaatgcctt acttctttga ccaagcaaag gtcatttgcc tttgtcacta cgatggggta
     7441 cgtgatttta ggcgttaaaa agtagtgatt atatcaactt tacgagtaaa tataaattta
     7501 gacatgaaac tgaattatcc aatggaaaat catggtttat aatctagaaa aattatagta
     7561 atgattggat tatatatatt ctttcgtatt ttcgtacaac tgtagcttgt caaaattgag
     7621 aaatttaacc gattaggtac tttacatcgt tatttgggta atttctaaaa catgaagctt
     7681 accaacgaat aaactgagac tatcttatta attgatcaat ataagaaaat atctttgagg
     7741 agatgatgta ctatgttttc gtctatccac gattggttag gtggtctttt cggcggtgga
     7801 ggtaaaggtt tttaa
//
LOCUS       DARPZF010000084         7699 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.089, whole genome shotgun sequence.
ACCESSION   DARPZF010000084 DARPZF010000000
VERSION     DARPZF010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7699
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.089"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            544..1107
                     /locus_tag="SLE65_002608"
     CDS             544..1107
                     /locus_tag="SLE65_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8449853.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(1386..1673)
                     /locus_tag="SLE65_002609"
     CDS             complement(1386..1673)
                     /locus_tag="SLE65_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEI8449854.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(1663..1992)
                     /locus_tag="SLE65_002610"
     CDS             complement(1663..1992)
                     /locus_tag="SLE65_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEI8449855.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            2297..2626
                     /locus_tag="SLE65_002611"
     CDS             2297..2626
                     /locus_tag="SLE65_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8449856.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(2913..3398)
                     /gene="vanZ"
                     /locus_tag="SLE65_002612"
     CDS             complement(2913..3398)
                     /gene="vanZ"
                     /locus_tag="SLE65_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HEI8449857.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(3551..4462)
                     /gene="vanY"
                     /locus_tag="SLE65_002613"
     CDS             complement(3551..4462)
                     /gene="vanY"
                     /locus_tag="SLE65_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HEI8449858.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            complement(4890..5498)
                     /locus_tag="SLE65_002614"
     CDS             complement(4890..5498)
                     /locus_tag="SLE65_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HEI8449859.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(5504..6535)
                     /gene="vanA"
                     /locus_tag="SLE65_002615"
     CDS             complement(5504..6535)
                     /gene="vanA"
                     /locus_tag="SLE65_002615"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HEI8449860.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(6528..7496)
                     /locus_tag="SLE65_002616"
     CDS             complement(6528..7496)
                     /locus_tag="SLE65_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HEI8449861.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
BASE COUNT         2352 a         1532 c         1280 g         2535 t
ORIGIN      
        1 ttaaaacttt tttagcagat tttaaagttt cgtcaaaact aatatattct ggtagctgag
       61 cattcaaata gctttcagac ttcagaagaa aattacgagc atttttatag tccatctcta
      121 ataaagttat tcttttttta tccaatacat tcagctcaat tccttataat attctattcc
      181 ttagtatctc aacattattt actttataaa acgaataaat tttgtagttc taattcaaat
      241 attgcatgtt atatctaata tgggagcatt ttataatttt cattgtgata aactcgttat
      301 taactttagg atacactagt taggattaaa ttaggtatct agaaatttac ttaagatttt
      361 tttgtttatt tcgtatacac actcgtatca aaaacaatcg attatgagac aaaatgaaat
      421 gacctctttt attaaataaa agaggtcata ttttgtatca taacttgttg cattaactat
      481 gtatctataa ctccctttta tgatacaatc aagccagaat taaagtacga aaggaagaaa
      541 agcatgagtg gatacattta tggttatgcc cgagtgagta cacgttcaca agaactaaat
      601 cgtcaattag acttactcaa tgaacaaaat tgtaatgaaa tcctaactga gaaaatgacg
      661 ggaaccaaag cggttcgtcc ccaactaaat cgtttaaaag ataaaattcg tccgggagat
      721 acggtaattg tagaaagttt ttctcgattg ggtcgtagta caaaggattt gattgacctt
      781 gttacctatt ttgaagaaca ccatgttaag ctggtgagct tgaaagaaaa cttcgatacc
      841 agcacgcctc acggacgctt aatgatgact gtcttccaag catttagtca gttcgaacgt
      901 gatttaattg ttgaacgtac caaagaaggt ttgaaaagtg cacgtgcgag aggtcgtaaa
      961 ggtggccgtc cacgagtgaa ccagaaagat gttgatcgag cagtaaaatt gtataaaagt
     1021 caggtttata gcgtaaaaga aattacggaa atgactggta ttagcaaggc aacactctac
     1081 cgctacttaa aagacaatag ggaataatct attttaatct ttaggaatct ataatattta
     1141 tgggagaatt agagtgattt ttttattatt actaaaaaac aatataaaat aacgcatttt
     1201 aagccctctt tgtgcataag gatgaagctt ttaatttgaa agaggcttaa aatgcgtttt
     1261 aattttttct atttttcata aatatatagg ttagtggttt aaaattatag ggtattacaa
     1321 ctctcagctg ttaaaaatta tcttttaaag tgtcgtctat cctctcaagt tgaaacattg
     1381 ggttcttacc taatcttttt taattgttca taaaaatttt catgcgttcc acatagtaag
     1441 ataggtatca ctgcattatc tttaatttca tatgcaacgc gatatgtcgt acctgcatac
     1501 ttgaatccaa tagcccaaat tcctgataaa tcacccgttt tttgttctcc cgaatgagga
     1561 cgaactgcta tctcatcata aattatcgtt aaaaattgtt cttttaatgt tttctctttt
     1621 aattttttta gatactttat tacgtgttta gaaggtagaa tctcataagc caatttctgc
     1681 tgccaactcc tcttttgtca tcggtttaga atttgcaaca gtatcttcag caatagattt
     1741 aaatgcagaa gttaacgcat tttttctatt tctaaattct tttaagatct cttgtttgct
     1801 ataaccttct gaaagaatat cagccaaaat atcttcacta aaatcaaaaa attctttttt
     1861 aggctctaca aactcataaa ggataccatt ctctacaagc ttagcttcta cttcaacacc
     1921 attgggcaca tcgaattctt tagggaccgt taacataata gaatttcctt gttttcttgt
     1981 ttttgtaatc atattatttc ctccattatt ttacatttcg taattactta gtaattacat
     2041 tgtacgctat ttttagtaga aatacaaaat aataaaactc ctttagaaca attttcaaag
     2101 gagttttatt tgattaggaa attatgtaga ataataatat gtttttaact tggaatcaaa
     2161 aacgcacttg caagtaagtt tacttcaata catgaaattg cttataatag tgtattggaa
     2221 ttaaggtaga ttgacaaaag agtgatcaaa taggtatact tcattcaaat aatcgtttga
     2281 atgtgaggtg agatgaatga aaaaagtttg ccaagtgact gtcgtacata aagaaaaagt
     2341 aaatggaata aaaaataaat tggatcaaaa agatttttca aacttacttg tgttagggaa
     2401 atgtttcagc gatttttcta gaattaaaat tttctatgct ttagaaacct ataaggaaat
     2461 gtgcgtctgt gatttagcag aaatacttac tgctagtgtc gctacaacgt cacaccattt
     2521 acgtttttta aaaaaacatg gaatggcaaa atcacgtcaa gatggaaaag tagtttatta
     2581 ctctttagcg aatgaagaca tcctttccgc tattcgtgtt ttttaaagtt atcagaaaat
     2641 ctatctatga aatcttagtt tgggggtacc gtcaggaaaa tgcggattta caacgttaag
     2701 gaaatttatt aaagagacca attcctcagc actaaaattg ataattgggc tttctttgtt
     2761 actatagtgt taggtaagct ttttacttta tcaccggttt tcccctcact tcacacctac
     2821 gggcgagttt ccccacatcc cgttttccat ctaatccaat tcattcaata tctttatgtg
     2881 tatgaaagat cagattgctt gatttagaca tcttacacgt aatttattct taaatgggta
     2941 cggtaaacga gcaataatac gagcaaaagt atacctacaa aaataataac tctgtctaat
     3001 tttttttgat tcatatgctt attgcttaaa ccatataatt tcagtccaag aaagcctcca
     3061 acagtatttg taattacatc tgttatgtct gtcgctccaa tagcgaagat aaattgaatt
     3121 atttcaaaag taagacttaa aaccagtaca aaagcaaact taggtaaaaa tccgatttct
     3181 ttaaaattga cattcaaaag caagccaaat ggaataaaga ttataacatt atctatcatc
     3241 tctctgaaat tcccagtagc agtaaatgga gtcaagttaa gacttctttg atgataatta
     3301 aatactgata aaatattgta ttgtaatttg aataacacta accagattag tgtcactaaa
     3361 tataaagcta gcaatcctct agataatatt tttcccaata taatttcctc taattctttt
     3421 gtttaagttg tatcattagt atagcaatgt cctagttaac gtgggtttta aattaaaaag
     3481 ctaacgttac cccaaaagtg ctagtacaat aatgctgttc attaatttcg ttggtttcat
     3541 tccgccatcc ttacctcctt gaattagtat gtgttgatcc gggaaacact gtcacaatta
     3601 caccgtctat attgtttcct gatatctcat aacgaagatt agtcggcaca tgaatggtgg
     3661 tatttttagt aacaggataa taaaagatct catatttttc cccatttaca ctaacagaaa
     3721 tggttttttc ttcttttagg taatccatat attcctcgag aacgaaattc ttttctttca
     3781 taatcgcact atgtggtaaa ccaacatagc gaatatgcca tagttcatat tgaattcctg
     3841 ttaactctgt tttgtcctct ggataacgta aaatgaaccc gtatttccaa gcattttctt
     3901 ctatccactt tccttcaggg gctcgttcca ttttcgtcaa gcttgatcct acatctagtg
     3961 ataaacctga attatgctca ctataacctg ctggtaaggc atactcagcc cccatttctt
     4021 ggtaaagcac actttgctca tcaaagtctc gatagccact attaataata aaatgactaa
     4081 cgccaccctt tacagcatca ttgaccatct ctgaaaattt ttgtgctatt tcttttgaca
     4141 tataaatatt actatcaagc aacccgtatc catttattaa ttcgtcatgt ttagataaat
     4201 tcacgatatc tgacttcaca ctttcttggc gaacaggata tttactattg attaatagca
     4261 gatttccttg ataaacctgt tcttctgtaa ttgttttctc ttgggtattt tcagaagtcc
     4321 cactattttc taaatgttct ttgggatttt gatcataatt ttgaaattcg actttttcct
     4381 gagaaaacag tgcttcatta acgtagtcat aacctaagta tattaagaat aacaataaca
     4441 ataaaaaaaa caacttcttc attttcagtc tcctccttaa ctatatagtt ggaagtatga
     4501 aatatttcta gaatcttccc cttaaacggc acaatctcgt ttgagattgt gccgttttgc
     4561 cccgtaaatt acagtcaatt atttcgccct actggattta ctattatcac caatgtagat
     4621 gaattttcat aagtgatacc catgctgaat ttaacgaggc tgaactgcct gttgacaatg
     4681 ggcggtgtga aataccaccc ctctatgcga tcagtcttat tatcaggcta tcttgccgca
     4741 gcgcacgcag ataatgaccg caatatcgct ctgccttaca tcttcaatac tatctactat
     4801 atataaattc cctaagaacc agttacatac gtcgggtttc ctgccgaaag agttagctta
     4861 tatagtttgt ccgtgcaacg gttaaaagtt tatttaacgg ggaaatcaaa atagctattg
     4921 gggtatggtt cgtctcttaa tacatagtgc caccattcga ggctatatgc ttcaaaccca
     4981 ctgttttcca tgatggagcg caaacgtctg cgattttgcg cttcattgca tgatattcca
     5041 tttgccgcat gatgagagcg ttcatccata aaatcaaatc ggctccccat tggtacaagc
     5101 tcacccgtgt ctaatcgata aagcgtaaga tcaatggcac tgccgcggct atggcttgat
     5161 tttgaagcca cgtatccttt tgaaatcatc tcagttcggt caatattggg ataataactt
     5221 tcctttgtca ggttattttc cggctgtgca gcccattgca taaaacagtt tacagcacga
     5281 ttaggacggt aaccgtccca tagaagcaat ccgtaccctt gggtagcagc cagttctttt
     5341 gccttcaaaa gcgattcagc caactcgtat gtccctacaa tgcgatttac ttcataaccg
     5401 tcaaccggtt ttccggtgaa attatcccaa gtggcatatt tagcgtccca acgaacaccg
     5461 tgtactattt catctaaaaa agtaaatcct atttccatgc ttatcacccc tttaacgcta
     5521 atacgatcaa gcggtcaatc agttcgggaa gtgcaatacc tgcagcggcc atcatacggg
     5581 gataacgact gtatgacgtg aaaccgggca gagtattgac ttcgttcagt acaatgcggc
     5641 cgttatcttg taaaaacata tccacacggg ctagacctct acagccgagc gctttatata
     5701 ttttttttgc cgtttcctgt atccgtcctc gctcctctgc tgaaaggtct gcgggaacgg
     5761 ttataactgc gttttcagag cctttttccg gctcgacttc ctgatgaata cgaaagattc
     5821 cgtactgcag cctgatttgg tccacctcgc caacagctaa cgcggcactg tttcccaata
     5881 ccgcacaacc gacctcacag cccgaaacag cctgctcaat taagattttg ctgtcatatt
     5941 gtcttgccga ttcaattgcg tagtccaatt cgtccgcgct attgactttt ttcacaccga
     6001 aggatgagcc tgaacgcgcc ggcttaacaa aaacaggata ggtaaacgta gctgccaccg
     6061 gcctatcatc tttattaata acccaaaagg cgggagtagc tatcccagca tttttcgcaa
     6121 cgatgtatgt caacgatttg tccatacaaa ttgctgagct ttgaatatcg cagcctacaa
     6181 aagggatacc ggacaattca aacagacctt gtatggatcc atcttcacct gacttgccat
     6241 gcaaagctga aaatgctaca tcaacatggt tgatttcata ttcatggttc tttttaacaa
     6301 gtaatccgtg cattttttta tccggcgaga gtacagctga atagcaattg tcgttttccc
     6361 attccgcgca aggtttttcg cacattttcc atacaccaga tttcgtaatt ccaatgtata
     6421 acggctcgta tttttcttta ttaatgttag cggctatctc tattgcagat tttaccgata
     6481 cgtcatgctc ctctgagcaa cccccaaaca gtattgcaac ttttattcta ttcatgctcc
     6541 tgtctccttt caaaatccaa acagttttta atggtttttt caacggtatc acgcaacgct
     6601 tgctcggtat aataggccgt atgcggtgtg attatcacgt taggcattct ttgaagttta
     6661 agtaaaaatt gattatcaat tggtttttgg gtgcaatcag agtagaaaaa ctcttcctct
     6721 ccttccaata catccaatgc ggcaccgccc agtttcccgt tttctaatgc tttaaccaac
     6781 tcataggtat ctacaagtgg accgcgccca gtattgataa gaaatgctcc ttgcttcatt
     6841 ctctgtattt gttcgtggct gataatatag tgcgtatccg tattgagcgg cacatgaagc
     6901 gtaacgatat cgctattttg cagcaactca tcaaacggta catagtttac ctctatactt
     6961 cggctgcgac tataagccaa cactttacat ccaaatcctc gcagccgctc aataaccgct
     7021 ttgcctatct ggcccgttcc caccacacca actgtcatgt cgctgagtac cttgccacgg
     7081 tcgctgtcca acctgaaatc atgtttttcc acagagcgca caatcgattt tacgttgcgt
     7141 actgccataa gaattagcat catagtataa tcggcaacgc tatccggcga gtacgccaca
     7201 ttgtcgacag tgatgcccat tctcttagca gcagttgtat ctatatgatt gcagccgatg
     7261 cttcgggtag aaatatattt cacaccggct ctcttcagcg caagaagaat agaggcggaa
     7321 atctctgatt tatgtcccac actgatacat tgattgaaag gcgcggattt ggcgttggat
     7381 tccgacacgt tggcgttaat tatcgttgcc ataacgccaa agcgaggcga aagagcatgg
     7441 aatgcatctg cctcatcctg ctcacatcca taaacagtaa tgccgatgtt attcataatt
     7501 aagaccaacc ctttctgtga aaggcaccaa ataaaacggg gatgccaatg gtaatcttgt
     7561 caaatctttc tctgaagaac gaaaacggct cgttcttacg gtattaagtc taccgtgtaa
     7621 gaacgagccg tttcttaata ttaaattgtt aatttcctaa gaaaaagtaa agataacctt
     7681 gagattttcc taaaaaatt
//
LOCUS       DARPZF010000085         7625 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.090, whole genome shotgun sequence.
ACCESSION   DARPZF010000085 DARPZF010000000
VERSION     DARPZF010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.090"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(14..706)
                     /locus_tag="SLE65_002617"
     CDS             complement(14..706)
                     /locus_tag="SLE65_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEI8449862.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1143..1712)
                     /locus_tag="SLE65_002618"
     CDS             complement(1143..1712)
                     /locus_tag="SLE65_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEI8449863.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1786..2109)
                     /locus_tag="SLE65_002619"
     CDS             complement(1786..2109)
                     /locus_tag="SLE65_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449864.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2263..3075)
                     /locus_tag="SLE65_002620"
     CDS             complement(2263..3075)
                     /locus_tag="SLE65_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449865.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3429..4277
                     /locus_tag="SLE65_002621"
     CDS             3429..4277
                     /locus_tag="SLE65_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HEI8449866.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4422..5363
                     /locus_tag="SLE65_002622"
     CDS             4422..5363
                     /locus_tag="SLE65_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HEI8449867.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5353..7524
                     /locus_tag="SLE65_002623"
                     /pseudo
     CDS             5353..7524
                     /locus_tag="SLE65_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2272 a         1512 c         1371 g         2470 t
ORIGIN      
        1 agggggggat tttttatcgt tgtggaatat ttaaatacca acgcttgtca tgaaaatctt
       61 gtgctccacc cttagtattt ccttctggat cgtttgtcgc acgcatcatg acgtatactt
      121 tcttattagg gaaatcacgc atattgaaag atacatgata gccaacattt cctaaagtat
      181 tataagcttg atttacgtct ggtctataaa tcccatcagc tcttactcta gctagttctt
      241 ttccagtatt gtagtccata atgaaaatat actcgtattt ataattagca atgtgccatc
      301 cagctacatg caagtttgcg ttttcgattt ctccgaactg atcaatgtgg gcgtaatttg
      361 ttccatctgt cagcgtagaa tttgcagcac ctgctcgagt tggatcaatt actggtttat
      421 cctccgaagt agttggatta tcatccgtaa aaccatgagc caaatcatag gctagttttt
      481 ctttacttac acctatttca gaaagataac cgtaaggatc tgtatgatcg ccccaaatat
      541 tttgtgttac ccataaatgc gatttgattc ctggttggtt ataaggagtg tctaatgtta
      601 atggaatacc atatttcatt gctgaatctc ttgccaattc aacgtatact ttatagttct
      661 tttcaaaagt ttctttatca tgtgtgtgtt gtaactcgat ttgcacagga cttttggctc
      721 acgaggttgt cctactctac atcttgctga tagatatgct gaaaggaaaa caccaacatt
      781 atgttttgct ttttcagcta gaacgagaca agcaggaata cctttagaag atatcaaagg
      841 ttttttaggt cataaagatg tttccactac acaagtctat gcccatattt ctcccgaagt
      901 gaaaaaaaga tcaatgaatc aactagaaaa ctatatagaa gagcaaataa aaaagcactc
      961 aaattgagtg cttttttaag ctcactatca ctaaaactat cactaatttt atttataagc
     1021 gaacatgttt ctatcactga ttttttaaat ctagcgaaaa acccttatct taaaggcgtt
     1081 cgttcaattc tttggcaagg tcttcaaagc ctggcttgcc tagaagtgcg aacatggttt
     1141 tcttatagct catgtagaaa aattttcttg atgatgattt tatccatcaa ttgagattga
     1201 ctgttttgct ctcctatgat ttcagctatg attgtccgat tttgcggttt tcttcttaac
     1261 tggtagttga ttttcccagt ttccatcaac tcgctaagca tatccacgac tccgccaaat
     1321 ccggtctttt tcgtaataaa acctagtgct accattcgtt catctagatt ttttgctgta
     1381 atcgtcacac cagtaatgag cgagtgctgt aatgtttggg ccagctcttc catcccttca
     1441 gcattggata cgacggaagc tgttttgtta ataggttctt cgtttatttc ttttggttct
     1501 ttcctctcca ctttcactgt ttgacgaagg acatctagtt cttgcaagag cgtttcgtat
     1561 tgttcttggg tcagcatcac gccagctact ttttcacgat taaatatata tacgccagtt
     1621 cccgcgtctc gcgcttgagc aaatacatcc atcggcgatc gtttcacttc tgtgatcgaa
     1681 gatgtgggaa cttctaattt ctttaattcc aatggatttc ctcctttact aatcgctttt
     1741 tattatagca cagactgact tgttttgatc ttttttccaa aggttttatc ggtttttgcc
     1801 taaccagtaa ttgatatcgg taagaagtct ttcgatacca aatgaaggat ggtacagata
     1861 cgttttttga tcttcgttat ggtctagtgg aaaaaaatga tcgatgatca ctagatctgc
     1921 ataccgaggc ggcttatttc gagtacatac atgtatagag atccgttttc gatgtcttag
     1981 cgttttgttc agtaccccag caagtcttct tgcttcttgg tgttcatagc gaaaaaaaaa
     2041 gacgattttc acttcaggag ggtggacatc taaataccct cgttcctgga gtgttttcag
     2101 taaaagcatc ccccactcta ctgcggggtg tgcaagtgct tgttggatcg ctagccgaaa
     2161 ttgatatagt ttatctttgg aattgggaaa tttttctaat gtttcctgat aataacgaac
     2221 ttcttctatc agccggtcat ggataccaat tacgtaacga agtcattctt ggtaaagtac
     2281 ttttgtcagc tttgatttgc tttcgctctc aaattcgcta ttcagccaaa acagcgaatc
     2341 aagcttttca gtcacaatcg tcaatttccg atagtcttgt gtctcttcta tccgtttcca
     2401 ccgcttttca gtaatctggt tacagctcaa gcgcaaaatt gctagataat ttttttcttt
     2461 tattggcaaa atctgctcct ctctaaatag caattcagga aacaattcaa agaatagtgt
     2521 tcgactgtct cctaaaatct cgatttctgc cggatccttt ctttgcttca ataattggat
     2581 gaacatctca gaaaaggact gctctccatc atctgcaaaa aaatgcggaa aatctttcaa
     2641 aaagcaaaac agcagatatc ttacttttct ttctgaacca aagatctgtg cttttttata
     2701 agaaaaagaa aggtggtact cgccaaacca ctttctcaat cgctcttgcg tagaacgatc
     2761 gtacttctgc tcgtaaggtt cattcaatag cagatttttc agtaaacaaa acgggggtga
     2821 ttggatcaga aaaacaaaca agagataagg ttcgctatat ccttgatcat aaactaactg
     2881 aacggttttc ttatgaagaa tcagctgaat gggacagtcg ctttccgcca aacgtttcag
     2941 atgccgatcc actgttttaa catcgatttt cagttcttca gctaaatcag cttttcgcca
     3001 gatcaaatct ttcattagat tgattagtga aaataaattc tgtgcatttt ttgataatag
     3061 tttttgccat ctcatcgatc atttctcacc tgatttctaa acatattgtt tgatcaaaat
     3121 gggttcactc ctaaaaagat aaaaaactcc ctttctattt atttaaatac gcaaatcttc
     3181 ctcattattt tttattttac tcaatttaat cgtattctca tttcaaaacg aatgtacttt
     3241 aaaaaaacat aataagatca ctttgcttgt aggatgtatt cccttccatt acaatgaaat
     3301 aaatagcgat tttatgagaa ggtgatgtga aaatggaaga aaaaatagaa gaatccaaac
     3361 aaaaaatcga tcagttgata taagaattag aaaaagcggt catcggcaaa cgttcaacta
     3421 tccaattgat gatcgtggcc ctattagcag gtggtcatgt cttattcgaa gatattcccg
     3481 gtgtaggtaa aacgttactg gtcaaagcac tagcaaaagc tgtacaggga accttcagca
     3541 gagtccaatg tactcctgat ctgctgccta gtgatattct tggtttttcc gtatacaatt
     3601 cacaatcaaa agagtttgaa tttcgtccgg gaccgatctt taccacgatc ttgttagcag
     3661 atgagatcaa tcgtacgact cctcgtactc agtcagcact tttagaagca atggccgaga
     3721 atcatgcaac gatcgacaac aatacatacc ctctagacaa tcattttttt gtcttagcta
     3781 cgcaaaatcc aatcgagtac gaaggaacat atcctttgcc ggaagcacag ctcgatcgtt
     3841 ttttattccg actacaaatc ggttatcctt cttttgatga cgaacttttg ctacttttgg
     3901 ataaattcga aaaagtgttg gataacttaa atgaagtatt gaacagttat gaaatagaag
     3961 aaataaaaac aaatgtggcg aatgtctttg tcagtcccga agtggcatct tatgccttgc
     4021 agttagtgtc agcaacaaga agtcatgctg ccatccagct tggcatcagt ccacgaggaa
     4081 gcctttcctt tattcaggca gcaaaagctt atgctttaat ccatgggaga aattacgtca
     4141 cgcccaaaga tttgcaggat ttagttcctt acgtgttttc ccatcgcctg attttttacg
     4201 atcgttcatt gaaggaagac gaaaagaaac aaatcattca tactcttgtt gcacaaattc
     4261 ctattcctgt gaggtagatt gaggtagaca atggaaaaaa tcaaagatta tttcattaat
     4321 tttgtgttat ttctggtata tttcatcatt gtgctttttg ctcttgtatt caacaattct
     4381 ttaggctggt tcttgttggc cttttttact ctttatgtat catggagctt gatttcatta
     4441 agcagctttc taaagaaact ttcggttact tgtacattgc agccactcgt ttatcgcaaa
     4501 aaaagtatgc aggttatttt ttccatagca aaaaagagaa ctttttcttt acctctccct
     4561 cgtttacaaa tcggcttccc agcaatcttt gcagaaaaaa acaagagatt ttgattctta
     4621 caaataaacc gcaagaagtc caattgcttt ggcagccaaa agaaagagga tgccatgaaa
     4681 cattaactgt catttttaca gcctatgata gtctaggact tttcagaaaa agtgcaaaaa
     4741 gagagatctc ttttcctgtg actgttctgc ctgctttttg taagattcaa gcagaaaaat
     4801 tacagagagt tctggaaaaa aaacagcagc tgaacgcgta ccaaagaggt cttgattttc
     4861 gggaacatcg cgcttatcgt ccaggtgatt ctttcaaccg aatcgattgg aaattgtctg
     4921 ctcatactca agagtggtta taccgtgaat acgattatca agaagaagaa tgttctcctc
     4981 ttttttgctt ttggggttcg cccagtccaa aatttgaacc tctgctagac ttgtattttt
     5041 ctttatggca tttgagaaaa gaaaagcagc cggaacttct gatattaggc aaccgcgcct
     5101 ttcatggcaa agaccccggt catacctatt ttgcttcttt ggaagctggc gatgagaaaa
     5161 cttttttcgc acacttgaaa aaatatgcaa aaaaacaaat cgtcctcttt gttcctgaga
     5221 attctcctga agtctcagaa gctattgaaa cattgtcaaa agatcgaacg gtttatcttg
     5281 tttatttcgt agaaaaacaa ctcatggtcc aagaaaaaga caagatatgt tcattgccag
     5341 gaggtgaatg gattgacgat taaacgggaa aaatggctgc gtggcgttta ctcctttgtg
     5401 atactaagtg taggtgctcc gatatttgta gtagctaatc aattgcaaaa cagctacctt
     5461 cttatcctaa ctattggtgt cctatgcctt attgtctgct gtattcctaa aaaatgggta
     5521 cgtttgctgc tttctttgcc agtaatgata ggttgtttgt ttttatattt tccttcgaag
     5581 acattttcca tattatggat cttacagttt ttttcgtcag ttacagagga attcttccat
     5641 ctatcccaag gtaaacttta ttatttgcca gaaaagacag ctttttttct cataatgttg
     5701 ctgatctatt tatttattac attgaccgtg gattacgact attggtacgc accctttctt
     5761 tctttgatgg cttacttcat gatgcttacc gtttttcgga aaaaagattt actgtacgaa
     5821 atgattgcgg tagtaactgt tttgttcgtg tatctggcag caaggcaatt tttctccatc
     5881 cggttgttgt cgagaaacac tcgattccag tcattgacta cagttctgct tatttgtttc
     5941 ttaactttta gcgctatctt gcctttatat cttccgaaag tacaccaatc tctcgaggaa
     6001 acgagtgaac cgatccgaga atatcttaat gatgaagggc tttatgacac actccatgag
     6061 tatcaattaa ccggaagtgc aagaacaggc ttcagtgaga atgatgaaca gcttggtgga
     6121 cctttatatg ataatggcga agttgttttt acagcgaacc aaaaaggaaa tggctattgg
     6181 aagatcgaaa ataaaaatca ttacaccggt tctggatgaa tagaagatca ggacgcaccc
     6241 atccaaccaa tccaagaatt ccctgttgac atcacgagct accaaaccgt tatagaagac
     6301 aaagaaaaca ttacattgac cctaaaaaaa caagctttct taccttatcc ttatggaaat
     6361 actaccttga ctgatttttc attagctagt ggacaaacgc tttactattt gcctgaaagc
     6421 cagcgattca ttcctgtccc gaatgaatcg acacgttctg caactttaca aacagaaagg
     6481 ttagttttta cgagagaaga attaaaaagc agtcagttaa aagctgatga tttagaaaat
     6541 cagcagacaa atcttcaatt gccaaaaagt ttgcctaaac gtattgagga cttggcggtc
     6601 gaattgacca aaaatgaagc aactttaatt cgtaaagtcg aagctgtcta acagtattta
     6661 aaaacaagcg gaaatttccg ctattccaaa acggataccg ggcatactcc aaaagaacac
     6721 gattatgtgg attatttcct ctttgattca aaagtcggct attgtgacaa cttttcaact
     6781 tctatggtcg tccttcttcg aacacttggt atcccagctc gctggacaaa aggttttaca
     6841 aatgggctca gaacaggcac agataatcaa gggaatgagg aatacagcat tctcaatagt
     6901 catgctcatt cttggccaga ggtatacttt cctggatttg gctggcttcc atttgaacca
     6961 accccttcat ttgccaatcc aatgggttca caaccagttg ctgaaacaac cgaaaccgtc
     7021 cagcctgcta tcgaacaacc aaatgaaagc gaaaatatgg cagaaactat ttccagtgag
     7081 agatctgagg tcattccatc agaagaaaca acactcacac cagcttataa aatcgtctta
     7141 ttcagccttg gagtgtgttt atccgtcttg ttgttctttc tattgttatt cagaaaatct
     7201 ctgcgctgga caagttatct tatctatctt catttttttg cttctactaa tacgattgca
     7261 tatcaaaaac ttcttaaccc tttggaaaca ttggtaccgc gcaaacccgc agaatctttg
     7321 caggaatata gcctgcgaat agaacaagaa ttcaagctag atctgcgttt cattcgatta
     7381 actactcaat atgaagcaga aatatatgga cgacaagcag atccggtaaa attcgataaa
     7441 aaaacctatt tagaaataac gcatataata agaaaaacgg tatacaaaaa aattctgaca
     7501 aaagggagcc gcttcaaaaa ataagataaa atttctggag aatctacttc tcgaatgccg
     7561 agaaccagct gattgagtat cgattactcg aaaaaaaggt tgtgacacgt tttttgtcac
     7621 aacct
//
LOCUS       DARPZF010000086         7596 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.091, whole genome shotgun sequence.
ACCESSION   DARPZF010000086 DARPZF010000000
VERSION     DARPZF010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7596
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.091"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(939..1352)
                     /locus_tag="SLE65_002624"
     CDS             complement(939..1352)
                     /locus_tag="SLE65_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HEI8449868.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1808..2293)
                     /locus_tag="SLE65_002625"
     CDS             complement(1808..2293)
                     /locus_tag="SLE65_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449869.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2432..2677)
                     /locus_tag="SLE65_002626"
     CDS             complement(2432..2677)
                     /locus_tag="SLE65_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HEI8449870.1"
                     /translation="MFYHLRKENSNENLDAIALTLLIVGGLNWLLVGLFELDLVAMIA
                     GGSTTIFAKIIYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2870..3670
                     /locus_tag="SLE65_002627"
     CDS             2870..3670
                     /locus_tag="SLE65_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8449871.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3689..5557
                     /locus_tag="SLE65_002628"
     CDS             3689..5557
                     /locus_tag="SLE65_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HEI8449872.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNAVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5550..6041
                     /locus_tag="SLE65_002629"
     CDS             5550..6041
                     /locus_tag="SLE65_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HEI8449873.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6029..6583
                     /gene="srlA"
                     /locus_tag="SLE65_002630"
     CDS             6029..6583
                     /gene="srlA"
                     /locus_tag="SLE65_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HEI8449874.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6601..7596
                     /locus_tag="SLE65_002631"
     CDS             6601..7596
                     /locus_tag="SLE65_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HEI8449875.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVPTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1215 c         1441 g         2233 t
ORIGIN      
        1 ttactatgaa taacataata agaaagtaaa gtggattgat ttgagatctt tttatacttc
       61 aaaaaagata acacccaact ttcaaaaata tgttttggaa gttgggacaa acgagttaat
      121 acattttaat acattatttt ttattcaaaa aaaatagcac aatggcaaag atcgtaagag
      181 agatcataag ccccaatgaa tgactaaaaa gaaaagcaga atcacatgcc atatcatccc
      241 atatttcttc aagaaaataa ataagcggga aaaagggaag gaatagtaga acatcgatcc
      301 agcaccattt ttttcttctt ttgaaataac ataaaacaat aaacatgaac gtgcagggaa
      361 gtaaaaacaa agctttactc ataactaaca aaataccagc tccttttatt tttttctccc
      421 ccacattcaa agagtaacaa tggtatgtac ttaataatag aaaaatggat caacttgtat
      481 gaataacagc tgaaaagatc tgcaccaaat aaaaaacttc cagccaaaac tgactggaag
      541 tttatttttt tctgaaatat tctaacacaa atatgaaaaa gatggccgaa gctaataagc
      601 cgatttcgta gcaaaacaat gagataccag agtcgtaata ataaaatcct ctaatcttat
      661 ggataaaata gatcatcgga caagcagata agagtaagta tttgttaggc cttttgaata
      721 agtaaaagaa agcactggtc attatgataa atggtatcca aaacaaaagt ttacttaaga
      781 caatcaaatg atcaactccc atatttttta ccaagagaga tcataacatc tttatcgtaa
      841 aaacaaaata tttttttgct cattttgaaa atttaaacat actcgttctt atccaaatat
      901 ataaaaatcg cccctcattc atcgagaggc gataagttct aatttaactc aatttttttt
      961 gtttcttttg gctgataagc tgttttaggt aataccaatt tcagcacacc gtttttaaag
     1021 gttccagtga ttttttcttc atcaacatta ggaagataga atgaacgttt gtaagagacc
     1081 gaatgtcttt ctttccgtac atagttgcca tcttctttat cttctgtatg ggactcatga
     1141 ttggcggaga tcgtcaaagt attatctgaa tattcaactg tcgtgtcttc tttgtcacag
     1201 ccaggcatat cagcagttag tttgtattct ttttcatttt cgactaaatc tacttttgga
     1261 taacttgaaa cacctaaaaa atcattgaat gctggactaa acacgtcatt gaaatcaggg
     1321 aacatgtcgc gaatgctagg tacatttgcc atttttgatc atcctttcaa taagtatttt
     1381 ttatttatcc ctatttacgt aataactcta ttttgaaaaa aatgcaagta taatggttag
     1441 ctttgtgaat atttcatcta atacgataca aaggctatct ttctaatttg aaaaagggat
     1501 cattaaaata ataagaagaa aatatgtcaa aaggtaaaaa agtaaattct tctatccaaa
     1561 tatagaaaaa ttgaatctag aaaaccgccc gacaataaat ttcattaact cagttgaccg
     1621 aaaatgaagt agataccaaa aatttatcaa gagagcaagt agagaagtga gtatattcat
     1681 aagagaaata gctgtaacga attattaggt taatgcaaat gcttatttat actccgtata
     1741 actttctcag aaaaaatgat accaataatg acttgctagt actgtaaatc cgtataatat
     1801 catctaatca aaatggtgtt ccatttgcat ctgtcatcgt aatcgatcct tcgggtgaca
     1861 ctcgataaaa accaacgctt ccagatcctc cttgggaacg gatttgtttg ctggaagctg
     1921 tgaacaaata atctcgatca attttttgat aaaagctaat aacaatatcg tcactttgta
     1981 attcggaacg gtgggcaata agaaatagaa gtgctttgtc agagttttct aatggaagag
     2041 aaggtacagt gctttcttgc atttcagatg ttgaagaaat gctaaacgac tgaatacttg
     2101 attggctatg ttgcgaatct acattaccag tagaagtatt agtaatggaa gtagtagaag
     2161 tacttttagt tgaaccaacc tcagttgttg aaatggctgc tgaagattct ttaacagaat
     2221 tctttgtttt atatccacag gcagaaaaaa gtattacagt tcccaacaag cctgcgtaaa
     2281 tccctttatg catgatagct cctcctaaaa tagattatct ttattcagta tatcacttaa
     2341 acaaagaaaa gcagatggtt taaaatgaaa aaaccttccc aataaaggga aggttcatga
     2401 agataataac ttttttaata attatagctt tctaatatct ttcatcaact tttctagtaa
     2461 tcattgggaa aaatttcaag cagtagatcg cacaaatacc tacgacgata taaatgatct
     2521 tcgcaaaaat agttgttgaa ccaccagcaa tcatagctac taaatcaagt tcgaacaagc
     2581 ctaccaacag ccagttcaac cctcccacaa tcaataaagt taatgcaata gcatctaagt
     2641 tttcattaga attctccttt cttaaatgat aaaacaatta tatatcaaaa agagaaacat
     2701 tgcttatata acgctcagga attttagcaa tctatgcaaa aagatgaaaa ttttttttgc
     2761 tcttccatta gtacacattt tttagctgaa gctgtaaatt tcatgtctta atttttttta
     2821 gtgagctttt atactggatt tgtaagaaaa aagaaggaga ggatcacata tgtcggattg
     2881 gttggatatt gcaggaaaag tagtaattgt aactggaggt tcctcaggaa ttggaagaag
     2941 tatcgtcgaa aatttgttga agcagaatgc acaagtagcg aattttgatg taactgaatg
     3001 ccgtatacag catgaaaacc tactatcttt aaaagtcgat gtgtcttcta aaacggacat
     3061 agaagaaggg atatataaag taatgaaaca tttcaagacg atcgatggtc tagtcaataa
     3121 tgcaggaata aatattcctt ctcttctaat agatagaaat catccaaaaa gcaagtatga
     3181 attatcagaa caagtttttg ataagatgat cgctgtcaat caaaaaagtg tatatttgat
     3241 gagccaagca gttggaagaa tcttggtgca aaagggatca ggagtgatcg tgaatctttc
     3301 ttctgaatca ggattggaag gatcagaagg acagagctgt tatgctgcta caaaagcagc
     3361 gatgaacagt tttactcgtt cttgggcaaa agagttagga aagaggaatg ttcgtgtggt
     3421 aggtgttgca ccagggatac tggaagaaac cggtttgaga acacaagaat atgaagaagc
     3481 tctttcttat acgagaggta taagcgtcga acagctgaga aacggttaca gtcgaacaag
     3541 tacgatccct ctaggaagga gtggtaagct gcaagaagtg gcggatctag tctgctatta
     3601 tctttcagaa agatcaagtt atatcactgg agtcacgact aatatttcag gaggtaaaac
     3661 aagaggataa aggatagggg ggacgcacgt gacgctagta aacagatggt accaattatt
     3721 gaaattacta gtcactcaca agaaagtttc aatccaggaa gtgcaaaaag aaatcaaaac
     3781 cagtaatcaa accataaaaa aagatattgg ggagttgaat gaagaaattg ccggtattgc
     3841 aaaaatcatc caaaaaaaca aacattttga acttgaaatt tatgattttg atttttttga
     3901 tgagatcatg caaggaaaat tgaaaacagc cagtgatttc aattcggcat ccaaaagaat
     3961 cgcttattta ctaaataggc tgatcgaaac agaggatttc ttacgtatgg atgatttgtc
     4021 tgaagaagtc ggtgtcagca gaggaacagt ggtcaaggat ctaaagacat taaaagagat
     4081 gatcaatgat tttgatgtaa agattacagg cacaccaaat aaaggactaa gaataatagg
     4141 agatgagcta gaattacgac tacttttatt ttattttgtt tctccctact tttcagagac
     4201 gaaaacagaa cagtttctag aagaaaaaca agcaatcaaa cattttcaga agaagacgaa
     4261 tgctagtaaa caagaaatca cccttttaac gaaagttatc ggtatttctt tgaatagaat
     4321 ctctagtaac tatctgttga agaagcccat caatcgttac agtgggtgtt ttgaatatat
     4381 ccaagaattc aatgaactga tcaatcagtt ggaagaaatc tatgaactaa ctttgagcca
     4441 atatgaaaaa gattttatca gttttccttt gaacatcatc aacacaagta taacgatgat
     4501 aaggaaagct aactctgatt tgcgcttata tttcgacccc atgatgatgc gtattcgacg
     4561 attagatctc attgatctgg atgagtcctt cttatatcaa gagatgaaac agcacctctc
     4621 tttattgata aatcgggtaa tttttcgtta tcgattgact gatttatttt atggtgagat
     4681 agaaaaaaag tatccttttt cttaccaaat cgctagcgaa tgcatacaag cattagaagc
     4741 tatcttgcaa cataagatct ctaaagtaga gatcagctac ctaacgttgt atttggagtt
     4801 agcatttcga tatcaaaaag agcatttttc ctctaaaaaa gtagccattg ttcatacgac
     4861 aggaaaagga acagcattaa tgatccaaag acaaatcaaa aggatattgg ggagggatat
     4921 acaaataaca catgtttcag aagaacaata tgaaaaagta gatctaaaca aatatttcgc
     4981 tgtttttaca acgattccgt taaaaaatgt aaatgaagag acaccggtga tccatttgac
     5041 taatcttttt gatgactctt ggttaagggc acaatggcaa aaagcaaaaa aaaagcgatt
     5101 agccgggttt cattctactg tttttttcta tcaaatatgg aaagaaaaaa agacgtatca
     5161 agaatattta aacaaattag tcgctccttt gatcagaggc tattatgtgg atgaagaatt
     5221 tgaaaaaagg atcttgaaaa gagaatatca gcaaagcaca tttgttaaca aagaatttgc
     5281 ttttcctcac acaaccaacc agctatctca acacattgtt ttatcagtag ggctaataac
     5341 tgatcaaggt ttagcagaaa caggaggaaa tgcagttatt tttttatttg ccatacctga
     5401 agaaatgacg gctgaagttg agaatgaatt atttgagcta tacgatatcc tatttgaact
     5461 cataaaaatg ggaatagatg agtttattga attagcaccg acacaagaat catttttaaa
     5521 actaatcaaa agtaaaggag agagacttca tgaatgatat gtatctattc atagttttcg
     5581 cagcttcagc ttatgtgctg caagcagtta tcagttggaa gcaactaaag catttcaatc
     5641 aaacatatag cgaactgcga agaaaaggaa aagtagcgat tggtaaacga cctgggaaaa
     5701 tccgttcagg cacgattgtt atgctagcta tagacgatca tgatcaagtt ttagaagtca
     5761 gaaaaatgca aggggttaca tctttggcaa aatttcattc attacctgtc tatgcgggtg
     5821 aagatatcca ttacatcgat cgttaccatc cctcagttcg agcggaagat cgtttgacac
     5881 aagcagcttt agaaaatgcc agagaagtat acttacgaat agaggcagga aatgaaaaaa
     5941 gtgaacaacc ttcattgcct tttattgcta tgctcaataa ttttcggata tggaaaagta
     6001 cgatcaaaga aaaaaggagt gacaaacgat ggatatcata acaaaatttg ctgagggatt
     6061 tatgaggctg ttccaaacag gtgcagaaac attcataagc tggatgacag gaatcgtacc
     6121 agttgtcttg atgctgatgg ttgcaatgaa tacgctgatt gcttttttag gtgaagaccg
     6181 agtaacgaaa gtagccaaat tatcagcgaa aaatccgctt actcgttacc ttgtgttacc
     6241 gttcttatct gcttttatgt tgggaaatcc tatgtcattt acaatggctc gtttccttcc
     6301 agaatactac aaaccaagct attatgctgc tcaagctcaa ttttgtcata cgagcaatgg
     6361 tgtattcccc catattaatc ctggagaatt gtttgtatgg atggggattg ctcaagggat
     6421 cgaaacctta gggctaaatt cgatggagct ggctatccga tacttgcttg tgggactgct
     6481 gatgaacttt attggtggtt ggataactga ttttactact ggatttgtat gcagacagca
     6541 aggaatcgtt cttagcaaaa aagtagagct ttcagttgat tagagaaagg agagttttaa
     6601 atgtatggtg atattaagat cgtaagagga aacggcgggt atggaggtcc tttgattatt
     6661 aggccgacaa aagataaaca caagttcatc tatgtcacag gtggaggtga gaggccaatg
     6721 atcgtagata aaatagaaga actgacaggt atggagtcta tcaatgggtt caaaacatca
     6781 atacctgata gtgaaatcgc gcttgcaatc gttgactgtg gagggactct tagatgtgga
     6841 atttatccta aaaaagggat accaaccatc aatatcgttc ccacaggaaa aagtggccca
     6901 ttagcacaat atatcactga agatatttat gtttcagcag tagggttaga acaaatacag
     6961 ccactaatgg aaactgatga taacaaagaa acagtaaata ctgcatctcc agataaaaag
     7021 tacaaatatg atacttctaa aaagataacc gagcaaaaag cagagcagca aaactggata
     7081 gcaaaaattg gaatgggcgc gggaaaagta gttgctacat tcaatcaatc agcaagagaa
     7141 gcagtagata cgatgatccg gacagtgatc ccttttatgg ctttcgtttc ccttttgatt
     7201 ggtgtgatac aaggttctgg gatcggtaat gtatttgcta acattatggc acctttagca
     7261 ggaaatgcag ttggattaac aatcattggc tttatttgtt cactgccatt tttatctcct
     7321 ttgcttggtc caggggcagt tattagccaa gtgattggaa cattgatcgg tgtagagatt
     7381 gggaaaggaa atattcctcc ccaattagca ttaccggcac tatttgctat caatactcaa
     7441 aatgcatgtg attttattcc agtcggtcta ggtttggaag aagcaaaagc tgagacagta
     7501 gaagtaggtg taccatcagt tctttattca agatttctta acggcatccc acgagttatc
     7561 attgcttggg tagcaagttt tggattatat agctga
//
LOCUS       DARPZF010000087         6675 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.093, whole genome shotgun sequence.
ACCESSION   DARPZF010000087 DARPZF010000000
VERSION     DARPZF010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.093"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            70..153
                     /locus_tag="SLE65_002632"
     CDS             70..153
                     /locus_tag="SLE65_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEI8449876.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            278..1015
                     /gene="erm(B)"
                     /locus_tag="SLE65_002633"
     CDS             278..1015
                     /gene="erm(B)"
                     /locus_tag="SLE65_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEI8449877.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1185..1445
                     /locus_tag="SLE65_002634"
                     /pseudo
     CDS             1185..1445
                     /locus_tag="SLE65_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1608..2273
                     /locus_tag="SLE65_002635"
                     /pseudo
     CDS             1608..2273
                     /locus_tag="SLE65_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2309..2554
                     /locus_tag="SLE65_002636"
     CDS             2309..2554
                     /locus_tag="SLE65_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEI8449878.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2657..3526
                     /locus_tag="SLE65_002637"
     CDS             2657..3526
                     /locus_tag="SLE65_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HEI8449879.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3507..4241
                     /locus_tag="SLE65_002638"
     CDS             3507..4241
                     /locus_tag="SLE65_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEI8449880.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4274..5189
                     /gene="ant(6)"
                     /locus_tag="SLE65_002639"
                     /pseudo
     CDS             4274..5189
                     /gene="ant(6)"
                     /locus_tag="SLE65_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
     gene            5186..5728
                     /gene="sat4"
                     /locus_tag="SLE65_002640"
     CDS             5186..5728
                     /gene="sat4"
                     /locus_tag="SLE65_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HEI8449881.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5821..6615
                     /locus_tag="SLE65_002641"
                     /note="aph(3')-IIIa"
     CDS             5821..6615
                     /locus_tag="SLE65_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HEI8449882.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT         2340 a         1005 c         1393 g         1937 t
ORIGIN      
        1 tttgtgtata ataggaattg aagttaaatt agatgctaaa aatttgtaat taagaaggag
       61 ggattcgtca tgttggtatt ccaaatgcgt aatgtagata aaacatctac tgttttgaaa
      121 cagactaaaa acagtgatta cgcagataaa taaatacgtt agattaattc ctaccagtga
      181 ctaatcttat gactttttaa acagataact aaaattacaa acaaatcgtt taacttctgt
      241 atttatttac agatgtaata acttcaggag tgattacatg aacaaaaata taaaatattc
      301 tcaaaacttt ttaacgagtg aaaaagtact caaccaaata ataaaacaat tgaatttaaa
      361 agaaaccgat accgtttacg aaattggaac aggtaaaggg catttaacga cgaaactggc
      421 taaaataagt aaacaggtaa cgtctattga attagacagt catctattca acttatcgtc
      481 agaaaaatta aaactgaaca ttcgtgtcac tttaattcac caagatattc tacagtttca
      541 attccctaac aaacagaggt ataaaattgt tgggagtatt ccttaccatt taagcacaca
      601 aattattaaa aaagtggttt ttgaaagcca tgcgtctgac atctatctga ttgttgaaga
      661 aggattctac aagcgtacct tggatattca ccgaacacta gggttgctct tgcacactca
      721 agtctcgatt cagcaattgc ttaagctgcc agcggaatgc tttcatccta aaccaaaagt
      781 aaacagtgtc ttaataaaac ttacccgcca taccacagat gttccagata aatattggaa
      841 gctatatacg tactttgttt caaaatgggt caatcgagaa tatcgtcaac tgtttactaa
      901 aaatcagttt catcaagcaa tgaaacacgc caaagtaaac aatttaagta ccgttactta
      961 tgagcaagta ttgtctattt ttaatagtta tctattattt aacgggagga aataattcta
     1021 tgagtcgctt ttttaaattt ggaaagttac acgttactaa agggaatgga gataaattat
     1081 tagatatact actgacagct tccaagaagc taaagaggtc cctagcgcct acggggaatt
     1141 tgtatcgata aggggtacaa attcccacta agcgctcggg accccttgta ggaaaatgtc
     1201 ctaagtgtgg caacaatatt gtattaaaaa aatcgtttta tggttgttca aattatcctg
     1261 aatgtaagtt tactttagct gaacatttta gaaagaaaaa actaaccaaa acgaatgtaa
     1321 aagaattact ggagggaaaa gaaaccctgg taaaaggaat caaaaacaaa gagaaaaagc
     1381 cctacaatgc cgttgtaaaa attggggaaa agggatatat tgattttatc tctttttcaa
     1441 aataaacatg gggctgaccc aaaagtagct cctatatgaa aaatagaggt ctttccattt
     1501 agatagtagt ggaaagacct ctatttatct tttgaaagtg aatacaaaaa taaagcacac
     1561 tctgctataa tataggtgat taatccattt gagagaggtg ctttatcatg tatcaaaatt
     1621 ataccataaa ccaactttgt ttgcctatag atcttgaaat taaattagaa gaaaatgatt
     1681 ttgctcatgc cattgtgcag tttgttgact ctattcccga tgaagtcttt cttccttatt
     1741 atcaatctat gggtagaccc caatatcatc ctcgtatgct actttccatt attctttgtg
     1801 cctatattca aggggtttat tcgggccgcc aaatacaaaa tatgctgata gatagtattc
     1861 ggatgcgcta cttatctcaa gagcaattcc ctaactttcg tactattaat cgttttcgcg
     1921 ttcatccgat tatgaacgat attctagatc attcatttgt tcaatttcgt gagctactgg
     1981 ttcaaagtgg cttaatcagt ggcagtgctc tatacattga tggtacaaaa attgaagcgg
     2041 atgcgaataa atactctttc gtttggaaaa aaagtatttt aaagtataag gatagccttg
     2101 atcaaaaagc ccttgaaaac taccaacaaa tggtggaaac aaaaatctta cctgagttaa
     2161 tagatgattt aaaggatgaa ctttctatag aagagattga aaggattcgt caatctttgg
     2221 aagaaaagga aaatcaatta attgaagcga ttgaccaaac cgaaacagta gaagggggct
     2281 gacccattat taataaggag tggacaacat gattgatgta aatgagctat tggaagaagc
     2341 tattagagaa actgaaaatc taaatgatgg cgaagttttt cttgttaaag atttattcaa
     2401 gggatatgtg gggaatagga tacccagaaa ggatcgactt ctgcttggaa cgttattttt
     2461 aaaccatgtt agcaaaatga atggtaattt aaaggctatt gaaaagactt catctaatca
     2521 gcagaggtat aaaaagacaa ttgataagtt ttaactatct tttgtgaaat taaaaaaatt
     2581 ataaatatgt tgagtagaag caaaagattt ggcttggaat ttttacagca gtgaatcgat
     2641 aaaaggagca tgcttgatgg tagataatat tattaaatca gtagcagaga aattatcctc
     2701 tctgtcttat atagaaggta ttgttttagg tggttcacgt gcaaggggca cccatacaga
     2761 ggattcggat atagatatcg gcatctatta caattcagaa tcatttgaca taaatactat
     2821 taatcaattc gctacaaagc tggatgatga gcatagaaat aaccttgttg tacctcccgg
     2881 agcatggggt gattggatta atggcggcgg atggttagtc ataaacgggt atcatgtgga
     2941 tttaatttta cgtgatatta aacgtgtgga acaaataatg aaagatacag agcacggaat
     3001 tgttactgcc aattatcaga ctgggcatcc ccatggttat attagtgcaa tgtatcgagg
     3061 agaattagcg attagcaaaa tactatatgc taagaatgaa agcttatgcg aattaaaaaa
     3121 acaggcagaa acttatccca atgctttgca gaaaagttta gttaactttt ttatgtttga
     3181 agcagggttc tctttaatgt ttgtaaaagc aaattcggga acagacgata aatattatat
     3241 tgcgggtcat gtttttcgta tagtttcatg tttaaatcaa gtgttatttg catgtaataa
     3301 tgcttattgt atcaacgaaa agaaagctat aaaactgctt gaaacttttg aacataaacc
     3361 tgaaaaatat accgagaagg taaatcatat ttttgaagta ctcggtatct cactttttga
     3421 atgctacgac atgaccgaga agctttataa tgaagtgaat gaaattgtat cggagataaa
     3481 taacttttta aacgaggaga gttcagatga aagaaaacaa atatgatgat aatatatttt
     3541 ttcaaaaata cagtcaaatg agtcgctcgc agaaaggact ggctggtgcg ggagaatggg
     3601 agactttgaa aaagatgcta cctgatttta agggtaagcg tgtgcttgat ttaggatgcg
     3661 gctatggatg gcactgtata tatgcgatgg aaaacggtgc ttcctctgta gtaggtgttg
     3721 atatttctca taaaatgctc gaagtagcaa aaggaaaaac ccattttcca cagattgaat
     3781 atgaatgctg tgccatagaa gatgtggatt tcccagagga gagctttgat gtaatactaa
     3841 gttcgcttgc gtttcattat gtagcagact atgagaattt aataaaaaag atatatagga
     3901 tgctgaaggc tggtggcaat ttagttttta cagttgaaca tcctgttttt actgctcatg
     3961 gaacacaaga ctggtattat aacgaaaaag gagaaatact gcatttcccg gtggacaatt
     4021 attattatga gggcaaacgg acagctatgt ttttggaaga aaaggttaca aaatatcata
     4081 gaacactgac cacatatcta aatacactgc tttcaaatag ttttataata aatcagattg
     4141 tggagccaca gccgccagag aacatgatgg atattccggg gatggcggat gaaatgcgac
     4201 gcccaatgat gctgattgta tcggcaaaaa agaagatgta ataatataga aaaaataaac
     4261 gaggagtatg taaatgagat cagaaaaaga aatgatggat ttagtacttt ctttagcaga
     4321 acaggatgaa cgtattcgaa ttgtgaccct tgaggggtca cgcgcaaata ttaatatacc
     4381 taaagatgaa tttcaggatt atgatattac atattttgta agtgatatag aacctagaac
     4441 cgtttatatc taatgatgac tggcttaatc aatttgggaa tataataatg atgcaaaagc
     4501 cggaggatat ggaattattc ccacctgaag aaaagggatt ttcctatctt atgctatttg
     4561 atgattacaa taaaattgat cttaccttat tgcccttgga agagttagat aattacctaa
     4621 agggcgataa attaataaag gttctaattg ataaagattg tagaattaaa agggacatag
     4681 ttccgactga tatagattat catgtaagaa agccaagcgc aagggagtat gatgattgct
     4741 gcaatgaatt ttggaatgta acaccttatg ttattaaagg attgtgccgt aaggaaattt
     4801 tatttgctat tgatcatttt aatcagattg ttcgccatga gctgctgaga atgatatcat
     4861 ggaaggtcgg catcgaaaca ggctttaaat taagtgtagg caagaactat aagtttattg
     4921 aaaggtatat atccgaggat ttgtgggaga aacttttgtc cacctaccgg atggattcct
     4981 atgaaaacat atgggaagca ttatttctat gccatcaatt gttcagggcg gtatccggtg
     5041 aggtggcgga aaggcttcat tatgcctatc cggagtatga taggaatata acaaaatata
     5101 ccagggacat gtataaaaaa tacactggta aaaccggctg cctggatagc acatatgccg
     5161 ctgatataga agagaggcgg gaacagtgat tacagaaatg aaagcagggc acctgaaaga
     5221 tatcgataaa cccagcgaac catttgaggt gataggtaag attataccga ggtatgaaaa
     5281 cgagaattgg acctttacag aattactcta tgaagcgcca tatttaaaaa gctaccaaga
     5341 cgaagaggat gaagaggatg aggaggcaga ttgccttgaa tatattgaca atactgataa
     5401 gataatatat ctttactacc aagacgataa atgcgtcgga aaagttaaac tgcgaaaaaa
     5461 ttggaaccgg tacgcttata tagaagatat cgccgtatgt aaggatttca gggggcaagg
     5521 cataggcagc gcgcttatca atatatctat agaatgggca aagcataaaa acttgcatgg
     5581 actaatgctt gaaacccagg acaataacct tatagcttgt aaattctatc ataattgtgg
     5641 tttcaaaatc ggctccgtcg atactatgtt atacgccaac tttgaaaaca actttgaaaa
     5701 agctgttttc tggtatttaa ggttttagaa tgcaaggaac agtgaattgg agttcgtctt
     5761 gttataatta gcttcttggg gtatctttaa atactgtaga aaagaggaag gaaataataa
     5821 atggctaaaa tgagaatatc accggaattg aaaaaactga tcgaaaaata ccgctgcgta
     5881 aaagatacgg aaggaatgtc tcctgctaag gtatataagc tggtgggaga aaatgaaaac
     5941 ctatatttaa aaatgacgga cagccggtat aaagggacca cctatgatgt ggaacgggaa
     6001 aaggacatga tgctatggct ggaaggaaag ctgcctgttc caaaggtcct gcactttgaa
     6061 cggcatgatg gctggagcaa tctgctcatg agtgaggccg atggcgtcct ttgctcggaa
     6121 gagtatgaag atgaacaaag ccctgaaaag attatcgagc tgtatgcgga gtgcatcagg
     6181 ctctttcact ccatcgacat atcggattgt ccctatacga atagcttaga cagccgatta
     6241 gccgaattgg attacttact gaataacgat ctggccgatg tggattgcga aaactgggaa
     6301 gaagacactc catttaaaga tccgcgcgag ctgtatgatt ttttaaagac ggaaaagccc
     6361 gaagaggaac ttgtcttttc ccacggcgac ctgggagaca gcaacatctt tgtgaaagat
     6421 ggcaaagtaa gtggctttat tgatcttggg agaagcggca gggcggacaa gtggtatgac
     6481 attgccttct gcgtccggtc gatcagggag gatatcgggg aagaacagta tgtcgagcta
     6541 ttttttgact tactggggat caagcctgat tgggagaaaa taaaatatta tattttactg
     6601 gatgaattgt tttagtacct agatttagat gtctaaaaag ctttaactac aagcttttta
     6661 gacatctaat ctttt
//
LOCUS       DARPZF010000088         6644 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.094, whole genome shotgun sequence.
ACCESSION   DARPZF010000088 DARPZF010000000
VERSION     DARPZF010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.094"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(1..859)
                     /locus_tag="SLE65_002642"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="SLE65_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="SLE65_002643"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="SLE65_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEI8449883.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="SLE65_002644"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="SLE65_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="SLE65_002645"
     CDS             complement(2143..2373)
                     /locus_tag="SLE65_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HEI8449884.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="SLE65_002646"
     CDS             complement(2603..3421)
                     /locus_tag="SLE65_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEI8449885.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="SLE65_002647"
     CDS             3582..4271
                     /locus_tag="SLE65_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEI8449886.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="SLE65_002648"
     CDS             4285..5787
                     /locus_tag="SLE65_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEI8449887.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="SLE65_002649"
     CDS             5800..6276
                     /locus_tag="SLE65_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEI8449888.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="SLE65_002650"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="SLE65_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1032 c         1204 g         2236 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atgt
//
LOCUS       DARPZF010000089         6462 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.095, whole genome shotgun sequence.
ACCESSION   DARPZF010000089 DARPZF010000000
VERSION     DARPZF010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.095"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(109..564)
                     /locus_tag="SLE65_002651"
     CDS             complement(109..564)
                     /locus_tag="SLE65_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449889.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(718..1926)
                     /locus_tag="SLE65_002652"
     CDS             complement(718..1926)
                     /locus_tag="SLE65_002652"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEI8449890.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIQDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(2038..2370)
                     /locus_tag="SLE65_002653"
     CDS             complement(2038..2370)
                     /locus_tag="SLE65_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HEI8449891.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            2518..3393
                     /locus_tag="SLE65_002654"
     CDS             2518..3393
                     /locus_tag="SLE65_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEI8449892.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(3475..4056)
                     /locus_tag="SLE65_002655"
     CDS             complement(3475..4056)
                     /locus_tag="SLE65_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HEI8449893.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(4062..5321)
                     /locus_tag="SLE65_002656"
     CDS             complement(4062..5321)
                     /locus_tag="SLE65_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEI8449894.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(5323..6369)
                     /locus_tag="SLE65_002657"
     CDS             complement(5323..6369)
                     /locus_tag="SLE65_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449895.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
BASE COUNT         1799 a         1338 c         1103 g         2222 t
ORIGIN      
        1 aaatcttgtc acagtccctt attctgaata aacggtgtgg aagagacagc ctatcagtag
       61 taataagaca catctctttc acagcctcat ttttgcgtaa aaatcgattt attcgaaaaa
      121 ttccccgtat acatcttcta cacgttgatc tggattgatc acgatataca agttacctgt
      181 tttttcgctg atttttgttg attgatattg attgtctaat ccttctgttc ctttatctag
      241 atatgggaag tacacaagat caggtgtgcc atttcggtaa aggatttcca ttcgctcgat
      301 atcttcgtat ttcaatgcgc gattaaacat gcccatttcc agtccgccta ggttgatatc
      361 atgtgtcgca actgcgtccc cttcatggaa gatttcgatt ttaaatccag cacacggatg
      421 gatttcaaca aattcactgc cattgattcg tccaaaactt gttgtgattt gtttgatcca
      481 aagatcgccg atatgacggc ggttgatcgt ccaggtttct ccatttctaa aataaaattt
      541 tagcgctgtc atttctttac tcattaaaaa gactccttta tgatgtaatt tattcttgta
      601 ctacctcagt ttagcacaaa tttatgtaag tggtcacatc ttatgttttt tcttctaatg
      661 acgtatctgc ccactttaag tagccaacaa agctgagcag atacagtcta gtgtttttta
      721 aatcaatttt tctttcgata aaaaatccaa aacctgtttt ttatcatttt ttattctttg
      781 ttctacgacg gctttttcag ctaattgcaa agcttcacta acccacttac caggtttttt
      841 tccagtttct tctagcaaga ttttaccatc tactgctaat tcgcttaatg acttgatagg
      901 taaacgatca taggattctc ctacggcatc catctgaggt gtttcgtcaa aatagatcat
      961 caattcttct acttgcagtg catgtttttt gcctaagaag tacaattcga atggttccaa
     1021 agctccagtt tctcgttgtc gtagtccttg gacaagtgct tgaacgtctt gaatcatttg
     1081 gttagaacac ttccacgatt tcaaaaagga acgaatctca ttttctttta gatccagttg
     1141 gctgatcaat aatgcccatg cttggctctc ttctttcaat gggacggatg gtaattcagc
     1201 aaaacgtaaa agtgcttcgc cttcttcttt caaaccggga cagcaaatgt agcactctgt
     1261 ttcaataaat gcatggattc ccgcggcccg ttcatttccc aagagcatct tgatgaattc
     1321 cacatttata cgttctacag atattttacc taatagctcg tggttttctt tgatggcgta
     1381 gaaggtttct tcctctaatt tgaaccctag ttgactgaca aaacgcaacc cgcgcatcat
     1441 tcgtaaggca tcttcatgga accgctcatg aggattgcct acagctcgca agatctgttc
     1501 ttctagatct tgcagaccat cgaacaaatc gatgatttct ccatcttctt tcaaagcaaa
     1561 cgcattgatc gtaaaatctc ttcttttcaa atcttctgcc aacgaacgaa cgaattcgac
     1621 atgatctggt ctacggtagt cctgataagt tgattccgtc cgaaatgtgg tgatctcata
     1681 ttgttcatca ttttctaata ccaacacagt tccatgttcg atcccaatat ctatcgtttt
     1741 tggaaaaagc tgtttgattt cttctggaaa tgcgcttgtt gcgatatcca catcatggat
     1801 tggctggttc agcaagatat cacgaacact tccacctaca aaataagctt catatcctgc
     1861 attctctaat tttttcagaa ctggaattgc cttttggtat tccagaggta attgttttaa
     1921 tttcattttt ccaacctttc ctgcgtgttt cttgtcctga gataaagact cagttgcatg
     1981 gtgactgttt gacaagtccg tttcagagtc ttcaaggcca ggaccacttc atcttgttta
     2041 ctcgtcctta cgctcaaagc gattatggtc tctttgattg aatttttcca tgtttttttc
     2101 aaaaacttca gttaagtcga tattcaatga attagccatg atcatcgtaa cgaataaaac
     2161 atcaccaagt tcttctgcta ccgagttaac tggttcagaa gcctttttgc ttttttctcc
     2221 ataagtgtgg ttgacttctc ttgccaattc acctacttct tcagttaatc gagccatctg
     2281 agctaatgga gagaaatacc ccaccttgaa ttgctggata tattcatcca cttcctgctg
     2341 catactgtat aaagaacgct ttttatccat ctttttccct ccaaaactat cttaccaaaa
     2401 ctttaacgca aatcctagat aagagcactt gagaaaatcg aatttccatg ctacatttag
     2461 gaaggaattt ctaaatggaa attctgtgaa aatacataat tgaaagctgg aattcatatg
     2521 gtcaaacgaa aaacagtaaa agaagttctt tttatcatta taggaacaag tatttatgca
     2581 tttggtcttg tttacttgaa catcgctaat catttagcag aagggggagt ctcagggatc
     2641 accttgatct taagagcttt atttggtatt gatccagctt atacgacttt attaatcaac
     2701 atcccattga ttttactagg aggaaagatc ctcggtaaac gttccttggc ctatactgtt
     2761 ctaggtacac tttctttgtc attcttttta tggatctggc aaagggttcc actagaaatc
     2821 aatttacagc atgatctact gatcgtttct ctacttgcgg gtttagttgc aggtgtagga
     2881 agcgggatcg tctaccgcat gggtggaaca acaggcggca gtgatattat cgctcggatt
     2941 ttagaacaaa attacggcat cactatgggg cgttccctat tggcatttga tatcatcgtc
     3001 ttacttgctt cattaaccta tatcgacttg aaacgtatga tgtatacgtt gattgtttcg
     3061 tatgttttca gtcgtgtgat tgattcgatc ttagatggcg gatattctgc aaaaggtcta
     3121 cttgtcgtct ccaacaaaag cgaagagatt gcaccactac tgatgaccgg tctgcaaaga
     3181 ggtgtgactt tcctttctgg agaaggcgca ttctctggta attcaaaaaa aatcatctat
     3241 atggtcgtta gctctagtga attaactgaa gctaagagga tcgtccacga gattgacgaa
     3301 aaagctttcc tttcaatcat caatgtgcat gaagtggaag ggcaaggctt tacttatttg
     3361 aagccacaga caagattact gaaaaaacta taagaaaaaa gacaaagata ggctatgagg
     3421 aaagattcca catccagctg acctttgtct tttttagtac tatactattt ttaactaatt
     3481 gttatgttca cttacccggt tacttttctt ttgtgtctgc aaaaggatct ttcggttaac
     3541 ttcatcagat aatttcaaaa aagcatccct atctccatct tctagtgctt gatcgatttg
     3601 agcataaagc atttttagtt ttgcctcttc ttctttttct tgaaaatatc gttcaattaa
     3661 ttcagtatct tcttcactga ctgaagaatc ccaagaagaa aatggattgt cttctaagat
     3721 agatagatat tctcttgtct gccaagcatt ttcgaatata cattccacat ataaaggctt
     3781 tttccaattc aaacggattt catgaaaaat ctggtctgtg tccgtaaatt cttttccctg
     3841 caaaaacaat ttcatgggtt ccccttcaac agatagatca ctgatctgca gtcctcgatc
     3901 cgcaaaattc gccccttcaa caaagtggac attgcttaaa atcgcttcat gattggcaag
     3961 ataattcaag atccaaaaaa cttctcttcg gctaaaagat acatgattga ccatccacgt
     4021 taaaaaattc ttcttttccc gtacatcaat tagcattttt ctcacctctc tgttaggtca
     4081 tctaataatg acagtgcctc catatctcct ggttcaagtg ttaaataata agtcaataat
     4141 tcttgcgctc ttttcagctg cccttcttct cttaagaaaa aggcatactc tttcaagaaa
     4201 tctggttcat gtgatagttc atgataagcc tgttcatagt gtacagctgc aacggtaaag
     4261 tcttctaatt cattataagc atgggctagg ttccattctg cataaggatt agcagtttct
     4321 tccatctgat tgatcacttg tatcacatct tcatatcttt catcatccaa gtaaagatta
     4381 cttaaagtaa gtaatgtttc atcttgtttg tctcctactt ctaaagcttt cagtaaaagt
     4441 tcttctgctc gctgtctatc atgcagacgg aaagcatttt ccgaggccag gtgataaagt
     4501 tcgacttggt aaggattttc tttgattcct tcttctaaca ctgtttgtgc ttcttcaatc
     4561 atttcttctt cttgaagagc ttgtcctaga tatagatata acgattgata atgcggatta
     4621 acttctcgaa gttcttccag atagttgatt gcctgctgat tttctttcaa ttgaagattc
     4681 gtaaaagcta gctggaacag tcgatcatct gtcctttctt ctttcagtgc ttcttctaaa
     4741 ggtacgatag ctgcttcgaa ttctccttgc atacttaagg attgtcctaa acgttcctgc
     4801 atcgagattc ctgaaatttc atttatcccg cttgccaaca atgtttcata aaccactgct
     4861 gcctctttga aacgatcaac tgaaaaatac aattcagcta gcgcaaactg gatcaatggt
     4921 tcatcaggaa gcaacccagc tgcttctttc aattttgctt cactcacttc agggattccg
     4981 ataacttggt acaaatcagc tatcgccaat aagctttgcg gatagtaatc actttgctta
     5041 tccacttttt ccaggtattc aaaagctaag tcgatctcat tatcttcgat tgcaatttct
     5101 gctaacggga tgttcagtcc gtcattttct gggtattggt tgatcagttg ttcaaaaatc
     5161 tgttttgctt cgatcaaaaa gccaatagcc agcaattctt cgcctagttc agctaatata
     5221 tctgctgggt cttcttttaa tgctttttct aaaaagattt gtgcttgtga caagtcttca
     5281 tctgataaag cttgcaacat tttttcgcta tttgtattca tttcaattcc ctcttatctc
     5341 actgacgatt tgttgaaata ccgtcattgt tctcaataat tctttttcgt ttggatgttg
     5401 gtatccgtct attataccta ttttttctaa aacaagtatt tttttgcttt tttctgccaa
     5461 aaaaagaact ttttccaaat actccatctt tgaaatctgt tccagccagt ggattggata
     5521 gccaagcaag tccagccaca caaaaaagtt ttttagttgg aaatcaaaag gatatgcttg
     5581 gagattccac acgaaatgaa acatcattcc taaaaatttt ttcatactag cagaaagtag
     5641 atggccattt tcggtcagat aaaaagcttg ttcaaacagt ttaccataat ttgacaggtt
     5701 ttctgcctct aattgataaa aatagatcat ttcttcgatc atcccggcaa acggccgagt
     5761 cgttaattgc tttttatttg gatagttttt atacagattt tgcaaaaaac gatgatcaca
     5821 aatcattccg caacagataa aagtcaaaaa gtcaatctgc tttccgtcca cctgccgctc
     5881 gctgattgtt tgatcataaa cgatgcgttc tggcagattg atggtttgca gcactacacg
     5941 atttggtagc tgcaaaatcg tccgctgcgg tgttaatgct cggcttagag aacggatcga
     6001 tacagggatc atccatagtg atgaatcaag ggttgtatgt ttttgaaaaa aacctgccag
     6061 atccatgatc ccttcatttc caaatccgat gataaacatg gattgatttt cgggatagcg
     6121 tttgacgaaa tcaagcaggt tctttaattc tgttaaatga ttgcattgag tgttggcaca
     6181 aatataccag tcattgtttg cttgatttgc aaataacggg ttgatcttat ctgcaaacaa
     6241 atcataatag cgctgattcg ttaaaaataa gattggctga tcaatggaaa gttctcttag
     6301 ctgactgact agcgtttctc cgtaaaacac tttcgtcaac gcatcttcta cttgataatc
     6361 aagttccata cgcatccctc ctcttcttat ttttatttta ccattagtaa gcaaattcta
     6421 gaaaagataa gagcaaagct cacctcataa cttggaaata aa
//
LOCUS       DARPZF010000090         6447 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.096, whole genome shotgun sequence.
ACCESSION   DARPZF010000090 DARPZF010000000
VERSION     DARPZF010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6447
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.096"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..115)
                     /locus_tag="SLE65_002658"
     CDS             complement(<1..115)
                     /locus_tag="SLE65_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HEI8449896.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDR"
     gene            246..698
                     /locus_tag="SLE65_002659"
     CDS             246..698
                     /locus_tag="SLE65_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449897.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            712..1401
                     /locus_tag="SLE65_002660"
     CDS             712..1401
                     /locus_tag="SLE65_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449898.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1526..3877
                     /locus_tag="SLE65_002661"
     CDS             1526..3877
                     /locus_tag="SLE65_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HEI8449899.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3957..4352
                     /locus_tag="SLE65_002662"
     CDS             3957..4352
                     /locus_tag="SLE65_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449900.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4677..5294
                     /locus_tag="SLE65_002663"
     CDS             4677..5294
                     /locus_tag="SLE65_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8449901.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5335..5634
                     /locus_tag="SLE65_002664"
     CDS             5335..5634
                     /locus_tag="SLE65_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HEI8449902.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5668..5835
                     /locus_tag="SLE65_002665"
     CDS             5668..5835
                     /locus_tag="SLE65_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEI8449903.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5880..6443)
                     /locus_tag="SLE65_002666"
     CDS             complement(5880..6443)
                     /locus_tag="SLE65_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8449904.1"
                     /translation="MIFKLRNRTEGLNIDKLFQEKASGKDTERPEFQKLLNYIREGDC
                     VIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLDTAMFDMFLSL
                     LSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLVFKTVVDMLKQ
                     GIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2210 a          903 c         1276 g         2058 t
ORIGIN      
        1 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
       61 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtta
      121 ttcctcctgc tatctttttc tattattcta tcttatttga tagtagattt aaaactttgc
      181 aacagaacca attatcttat cgtagatata tattataaat ttaataagaa agcgaggtga
      241 gaatcgtgaa aaaaacgata ctaagtattt tttcagtatt tacaatatta attgggggct
      301 attttctttt gaatttagat tctgttaatt caaacgctca aataaaagat caaagagtag
      361 ctgaacataa taataaaaaa atgagtttga ccaaaaatat ctattctatg tcagatgaag
      421 aattgtataa agaatttggt gatttatccg gggaacagtt agaagaaagt attccaggaa
      481 ttagtgactc agataaaatt gttgtcttgt ctgctggtgg gcaattaatg ggagatggca
      541 aatccgaatt agttagttat aaacaaaatc acagacagtt tattgatgtt aatactgatt
      601 ccaacgctat ttcgattaag gatctaaaag agcttttaaa tagtaaaaga aatgaattaa
      661 agcagataaa agaaactaat tcagtggaat tagagtaaag gaagattcat tatgaaaaag
      721 atttttggtg tttctgttgg gctacttatg atgttaacat ttggaaatgc agtatatgct
      781 gctgagaaag aagttatttc agatccagag cagtacgcct cacgatactt tgctgatttt
      841 gaagaagaag ataaagtact tgcattgcca gaaggtggtt ttttaaaagg ggaagctaaa
      901 attgtatcta tggataatcc agatataatt caaggttcat ataattcaga aactgatcct
      961 gcttcagttt cagtgacaga agcaaaaaaa attgttgctg aaaaattcaa aaatgatatt
     1021 gaaactactc caattatgcc tcgaggagca tttccacccg atgttggtac tagcggacac
     1081 cttcttgtac tagcaggagg aggaagctat aaatcacagc catttagtgg tgcgggatgg
     1141 cgttttggag gtatgggtgt aaaaccagct gatggtacag gcaacttttt acgttggaaa
     1201 tcctacattg acgatggaag agtaggaaat gtaaatcaag ccaacgcaac taaatctggt
     1261 tctattcaag gaatggcatt gtatgctcgt gaaggattca aatactttgc accaaacggg
     1321 cctggttgga caatgaatat aggtatttat tacacttata atcctgttgc aggtacgtat
     1381 tatgttgttc aaaatattta ataaaacagc acaaagagat ttctttgtgc tgttttatta
     1441 tttttagttg ttgacaaaca ctaaaatata aaatataatc aacacataaa cgaacgtatg
     1501 ttcggcaaga aagcagggga tttttatgga tgagatggtt ttaagtactc agaaatggct
     1561 aaacaagaaa tacagtaatg ttacagggtt tgataaggtt ccagaaaatg ggcgaacagg
     1621 gtggcctaca atctatggac ttattgaagg actacaagta gaacttggta ttactaatct
     1681 agtagctaat tttggaccta ccactgaaaa aatgtacgat aatcaggtta ctcctaaatg
     1741 gggcaaaaat ctacctaaaa atattgtatt tcttattcaa ggtgcctttt ggtgtaaggg
     1801 gattaatcca ggtggcttcg atggggtata tactccatat ttagatactg ctgtaaaaga
     1861 gttgcagact gatgcagggt ttaatggaag cgctgtaact ggagttttgg atgcgaaatg
     1921 ggccaaagcg ttatttgata tgagtgcttt tgttcttgtt cccggcggag atagtaaaat
     1981 tagaaaaatg cagcaatggt taaatgtaaa ttatttagaa tacacgggaa taatgccttg
     2041 tgatggtatt tatcaaagaa attcaaatca agcattaatt tttgcattac aagctgaact
     2101 aggatattct cccagtgaag caacagggtc ttatggtaat gggacaacta gtaaaactta
     2161 tcctgtgtct gaaggtaact cgggaaacta tgtaagaata attcaatatg gattatatgt
     2221 taatggttat tttgaagacg gtacattcga tggtattttc actaaatata tgggtttaga
     2281 agtactggca ttccgaaaat ttatggtatt gcctgaatat actgaaatag cagatgttgt
     2341 tgtaataaaa ggactattgt ctagcgctgg agatattaga agatctgcag atggcgcaga
     2401 tacttctacg caattaacta gatctcaaat ccaaacattg gttgataatg atataaaaat
     2461 agttggtaga tatcttactg gtactgttgg aattggaaaa gatgaacgaa ataagtatct
     2521 aactacagag gaattgaata atattttttc taaaaattta tctgtgtttc ctatctatca
     2581 agatggaggt gcagcattag cttattttac ttatgatcgt ggcttatcag atggtaagaa
     2641 ggctatagat gcagcaaaaa atctaaatat accattaaca acagttattt attttgctgt
     2701 tgatctagac atgttagggg aagaaattct tgcatatgct ggagaatatt ttaagggggt
     2761 atctgctgta atgtcatata gcgggtatca aacgggtgtt tacggaacaa gaaatgtttg
     2821 ttctcaaata atcaataacg ggtatgcttc gtttgcattt gtttcagata tgtcgactgg
     2881 ttatagtggg aatttaggtt ttcctatgcc tagacaatgg tcttttgatc aatttgttga
     2941 atttaccata ggaagtggca acggagctgt tggtatcgat ttaatcgcta catcgggtag
     3001 agatagcgga tttaatgagt tatcaaatga tactaataat gataattaca ttgccaaata
     3061 caatcagaag gttataaatc agatggtacg tgcgtatcaa tatctatcac aagctggtct
     3121 tgataatcct tggaaccctc atttgacatt ttatagatat gtaaattatt ctggtttgtc
     3181 atgggacatc atttcttctc ctgtaacaga gcatgataga aaaatttatg atgaatatag
     3241 gaataaatta actaatagcg agggcctgta taattatttt atagatccta atactggttc
     3301 aataataggt ttgcctcact taattgtgac gttacaatca cagatgtttc tagccgacac
     3361 aatcaatgat agtgtttctg actttgcagg ttggttagga gatttaatga cttgctgggg
     3421 tgaagttaag aaattaggaa tacaaatgga gcaaggtgta tttgcattag taggtacggc
     3481 tgcaggtgga acatttagtc tagaagattt ataccaagat gttgacgcgg taaatgttta
     3541 taccttagca aaaagaaatt ctgattcaac agctttatcg gctttaaaaa cgtactattg
     3601 tgataagggt gctattgata gatttaatca atttgttaag aacagatttg gttcttcaga
     3661 taaaatcgct tcagtaacaa atagtttatt agaaaatgac gaaacagttg atatcttagg
     3721 tgtagggata atttcatttt tcattgataa aatagttaat aattcacttg ggacagattt
     3781 tacttatctt gattttattg gagatgaggg gaaagttgca aatggatttt ctgaaaaaat
     3841 tattcaattt caagaaaata gaagtaaact taattaagaa tcgtttacta tttaaacagt
     3901 gtccttttcc tttttaaata tatacgataa aataagtata tgaattgtaa aaggacatga
     3961 tgattatgga agaaatagaa tggaataatc tgactcaaaa taataaaaat aattctggat
     4021 gtggaattat ctttatgttt gttatagttt tgggaatagt agtactttta ataactgtca
     4081 agatagtaga ttactttgcg aatactcctg aagaacaaat acagagaaaa cttcctgagt
     4141 ttgaaagagt accaccttat gatccaagag ataattcatt tcaagtaaaa aaattaaaag
     4201 agtctccaaa tgaaatgtgg tttgaagtta cagttgaatc aagcgacttc aaagaaaaaa
     4261 agaaagaata caattatatt gtaaaggcaa aagtatcaaa aagatttatt tttaacccta
     4321 aattagaaat atatagtgtt gtaatagaat aatagtgtta aaaaaattgt aaaagttaaa
     4381 gaagtcaaat tctgatgtga aaaataaaat ataccatgga agacataaaa gaaaaactgg
     4441 ataactagtt tatttaatgg cagaccgtta aggcctgcca tttttatgta ttttagcgga
     4501 ataaatataa tcatgcggga gtgtaaactt actgtttcaa aaagtatact ttttgacatg
     4561 ccttgatttt ctttgtttat gtatggcata ataaccacat aatacaattt gaaacgtttc
     4621 tgatttaatc tgattgtttt gaaacaattt tagtgaaaaa agggtagata aaaacgatga
     4681 gaaaattttt ttatatccgg gtcagtagtt atgatcaatc gatcgaacga caactgattt
     4741 ccgcgaagga attaggaatc cctgaagaat atatatttgt agaaaaagcc agcggcaaag
     4801 attttaaacg ccctgaatat caattaatga aacggatgtt tcgaaaagga gatttactct
     4861 atctacaatc attagataga ctaggcagaa ataaacaaat gattttagaa gaatggcgag
     4921 aattaactaa ggaaaagcag attgatattt ctgtgttaga catgcctctg ttagatactg
     4981 ctagttacaa gcaactagat gggttagaga cgcttatctc tgacttaatt ctgcaattac
     5041 tcagctatat ggccgaagac gagcggaaac gaattaatag ccggcaaaga gaaggcgtag
     5101 aagctgcgaa acaaaagggt gtaaaattcg gcagaaagaa aattgcttta cctcctgaat
     5161 ttcctgcgat ctattctgac tggaaagcag gaaagataac tgcagtctat gctatggatc
     5221 aattgggcat gaaacgaaat accttttatc gacgggtgaa agaatatgaa cataccttgc
     5281 accacttttc ttgatagata taacagctat tagacgggaa gggagagttt gaaaatggac
     5341 ttaacgaatc aaagggtcgt ttttactgga acgctgcagc aaatgacacg aacccaagcc
     5401 atcggtttgg ttcactcttt aaacggccat tgtcaatcaa gtgttacttc aaaaacaaat
     5461 ttcctggttt gtggtcagta ttctaagtcg ttgtttgatg attctctcta tacaaaaaag
     5521 gaacaaaccg cgcgggactt gattgcgtta ggtcatgaga ttaccatttt atcagaagtc
     5581 gaattttatg cgttaattag tcaacagttg aaagaatggc aacggtattt ataatcgtta
     5641 gtaaaattta caaggaggaa aatttttatg aagcgaaaat cttatgatcg ttggggcatt
     5701 gaaataacta gttttaatcg aaatattgct tttcacgtgg agtgtgactg tggggaatta
     5761 gcaaaaagtg tttatcaaaa aaattacttt tactgtccta aatgccatcg ccgatacggg
     5821 gtacatggaa catagaaacg aaatagtgcg gtagaaaagc gaatgaatgt agtatatttc
     5881 tacaaatcat tcgctttctt tattttataa atagttggtc gagagatccc gttttctttt
     5941 gcaatctctg caactggaat gccttgcttt aacatgtcca ccacggtttt aaaaactaag
     6001 cgtttttgcg gatctgttga gttaatagaa tactcgattg gtcgtccctt atatcggccg
     6061 gctttttgag ccaataatac tccttgccgc tgacgttcac gaattttctc acgctcgttt
     6121 tgtgcaatat aacttagcag tgataaaaac atatcgaaca tagcggtatc caggagttca
     6181 tttccagtat taaaatctaa aaactgtgca tctaatattt ttaacgctac ttttttctgt
     6241 ttcataaaag caactgtatt ttttatatct tcataatctc ttcctaaacg atctagtgat
     6301 gtaacgatga cgcaatcacc ttcacggata taatttagta atttttgaaa ctcaggacgc
     6361 tcagtatctt taccactggc tttttcttgg aataatttat caatgttaag tccttcggtt
     6421 ctgttgcgaa gtttgaaaat caaacgc
//
LOCUS       DARPZF010000091         6350 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.097, whole genome shotgun sequence.
ACCESSION   DARPZF010000091 DARPZF010000000
VERSION     DARPZF010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.097"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..209)
                     /locus_tag="SLE65_002667"
     CDS             complement(<1..209)
                     /locus_tag="SLE65_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449905.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNA"
     gene            complement(202..1527)
                     /locus_tag="SLE65_002668"
     CDS             complement(202..1527)
                     /locus_tag="SLE65_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HEI8449906.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            1977..2591
                     /locus_tag="SLE65_002669"
     CDS             1977..2591
                     /locus_tag="SLE65_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8449907.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(2756..3760)
                     /locus_tag="SLE65_002670"
     CDS             complement(2756..3760)
                     /locus_tag="SLE65_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449908.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINV
                     FFYSKEKLADFSNIAEMIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLE
                     LKTLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITA
                     CEIGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEK
                     RNKLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNK
                     SQITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD
                     "
     gene            complement(4219..4476)
                     /locus_tag="SLE65_002671"
     CDS             complement(4219..4476)
                     /locus_tag="SLE65_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEI8449909.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(4469..4738)
                     /locus_tag="SLE65_002672"
     CDS             complement(4469..4738)
                     /locus_tag="SLE65_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEI8449910.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(4869..5048)
                     /locus_tag="SLE65_002673"
     CDS             complement(4869..5048)
                     /locus_tag="SLE65_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449911.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(5429..5995)
                     /locus_tag="SLE65_002674"
                     /pseudo
     CDS             complement(5429..5995)
                     /locus_tag="SLE65_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6071..>6350
                     /locus_tag="SLE65_002675"
     CDS             6071..>6350
                     /locus_tag="SLE65_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HEI8449912.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAI"
BASE COUNT         1952 a         1200 c          943 g         2255 t
ORIGIN      
        1 tcagcgtttc gttcttcttt ttgaatagat actgatctat tttttatgac tgcagcgttc
       61 aatacttccg caatctcttc agtcgtcatt tgttcttttg ctaaattttg actggttcgt
      121 tgttcattgt cggcatcaat ttcttcagta tgatcagata aataaaaccc tgcccacttt
      181 aaacgtccac gatcattgta atcaatcatt tttaattccc ccatttccgc ccgcatgacc
      241 accaacaagt gtgcttctag taatgcttct agcgccttct aacattgaag aagcatgtac
      301 aatcgacgta aaaccatatt tttgccgaat cttgtcaata attttatcta aattttcttc
      361 gtcaatttgc ttttgtggat cactaaataa atccagctga agcgaatcgg tgtacacaag
      421 cttgctatag gttattccaa catgccttac ttcttgtcct tcataatact tatcaaacaa
      481 gaaaagacaa taattctgca attcctttgt attatctgtg atagggatct tcatctggtg
      541 tgaaaaccct ggtctcgttt ctaagatcga cgtgccaatg tgtaaatgga cacaacctgt
      601 tttacagtta tgctgcctaa tgcgtatcgc tacttgttcc gccatttctt ttaccaccag
      661 ctcgatttca tttcttctag tataatctcg tggtaacact tgtgaatttc catatgattt
      721 ttcctttgtc ggttctggtg ggattgctat atctgttcga tcgatcccat tagcatggaa
      781 gtacagctgt aagccaatca cacctagtct attcttaatc gtataaggat tccagttagc
      841 aagatctcta atgctcataa tccccatctg attgagtctt tttttcattc gagagccaat
      901 tccccaaaag tccgtcattt caggaatatt ccatactttt tcaggaacgt tttcgtacgt
      961 ccattccgca acaaatcctt cattatgctt tgcttcgttg tctaaggcta gtttagccaa
     1021 aaggggatta tctccgacac ctactgtagc aatcaatcct agctcttctt taatattctc
     1081 ctggatcatt tgagccagct tctttctccg ttgacttcgt gttccttcag tcgtaaaaag
     1141 attcagtgat cgggtcactt ttaagattga ttcatcgatc gagtaaatca gtagatcttc
     1201 atcagccaca tatcttctga aaatattatt tacctgcata tttcgcttga tatataggtt
     1261 catacgtggt ggaacaacgt gtagtgtttt aggaaatggt tgtggtaagt cacgtggtct
     1321 actcacattt gtaataccat accgcttttt tgcttcagga gaagaagcta atatcaatcc
     1381 tgaaccagta ttatcagctc gactcataac aacaagttct gttgttaatg gatctaaatt
     1441 tctttctata cattcgacac ttgcgtaaaa gcttttcata tcgattaaaa agtaatcatt
     1501 tactggctct tttgaataat ccatcataaa taacactcca ttctttcaca ttatacaaac
     1561 atatgttcga tattgtaaag aagaaatagc taaatacata aaaaaagaag cataggtatg
     1621 ctatcaccct gcttcttctt ttgatttgta tgatcaattt attctatcac tttactaatt
     1681 aatttgaaaa tctaataaaa actctcactc taaaagagtg agagactgca aattagagta
     1741 cggacttttt tggagttccg ttctttaata ttaacaaatg aataaaatcc ttacaacatt
     1801 tgagaataag ttatcagtag acacttacaa aaaattctca tactatttcc tccatcatta
     1861 gtttttgtct atataaggtt taccctaaat agacactggt ataacattga aaaatatggc
     1921 ttcctcgtgt atgattaggg tgtattttaa atagttgcag aaagtaggta aaagttttga
     1981 gagttgcata catacgtgtc tcatcgatcg atcaaaatga acaacgccag attgaagaaa
     2041 tgaaaaaatt cggtgcagag agaattttca tcgagaaaca atctggcgca acgattactc
     2101 atcgacctgt tttccaagaa gcattagatt acgtccgaga tcaagatatt tttattgtgg
     2161 aagctattga tcgacttgga agaaattatg acgagatcat cgcttcagtc aattacttga
     2221 agaagaaaaa tgtgaagctg atcattacta gtttaccgat catggctgaa gcaattggca
     2281 atcctctcct ggataaattc attaaggatc tgatcatcca aattttggcc atgatcgctg
     2341 aacaagaacg gactgaatcg aaacgtcgcc aggcacaagg aattaagatc gcaaaagcaa
     2401 acggcgtcta caaagggcgg cccaaattat acagtgcaga cgcaaaagat ccccaacgtc
     2461 gccttgttta caaaagcatc gttgaagatc ttaaaaatgg tgttgcgatt gctaagattg
     2521 ctaaagacta caatgttacg agacaaaccg tgtatagaat aaaaaaagac agcatggtca
     2581 atgacaaata gttgatcatg ctgcttttat tatcttctca tctttaattt cctacatata
     2641 attactatct ataaaattaa gtcttactca gaacagataa agcataaaat tccaacaaac
     2701 cattttttac ttaactaaat aaagagtctg ttaatataat cttcacttat ttacgttaat
     2761 cccctactgt atttgttggt tccttatcta tattttctac aaaatcctta ttatcttgtg
     2821 atttagcttc gtataattct ttgtatgtcg acacattggt tatactaatt cctatagcta
     2881 gttcttgaga ctctactttt ctctctagct cctttgacaa agtgatttga gatttatttg
     2941 gttccgttgg agtcaattct atagattctt cataaaaatc tctatacata aagctatcat
     3001 taattttata aaaaaaatta aatgttttta gcactgccat ataacattca aaacattctt
     3061 ctatagttgg tttacttcct tgaggagaat gaaccaattt attacgtttt tctatgaaat
     3121 ttttaatttc ctttcttatt tctttcggaa actcaatatt aaagtaccct ttaaacatgc
     3181 tccctaataa tttgtctaca gggggagatt gtaaattctc aaatattaga gttaaatcag
     3241 gtttctcttg ttgataaaat tcctttaccc ctatttcaca ggctgtaatt atcgaaataa
     3301 acctatctct agtatttgat atatttttac ttcttttaag gagtataaga gaaaagggga
     3361 tactttcgtg tccatgcatg taattaacta attgttgagc ttcagaagtt atatctctaa
     3421 ttatatagtt aacggaatta ggaagtgtct ttaactctaa tgaaatttct atccaattac
     3481 tatcttctaa tctgtatatg ctcgaagtat aatttgattc gtcagcaagc atcgctacat
     3541 cccaaacact gatcataaaa tcttttaaac gttcaatcat ttcagcaata ttgctaaaat
     3601 cagctaattt ttctttagaa taaaaaaaaa catttatatc agaatcaata aattctattt
     3661 tttttattac tatatcgtca tcattatctt gaccatttat gtttattgtt ccctgagtgg
     3721 ggagtacttc tttcaaattc aagttaaatt tatattccat tacttctcct ccaatatata
     3781 aaaattactt aactgtatcc aaatttaata tgtaaataaa tcattaattt ttagctaaat
     3841 tctatgagaa gtttattttt gttgtttttg ctaattaact aaaactagta caaaaaattt
     3901 aaaatagatt attaaaccta ttgcttattc tattcagtca tatatataag cgtcatcctt
     3961 tagtaactaa catcccacac tacaatagta ttataacata tctattcaac ttcaaattgt
     4021 tgaaatttaa gccatttata tttacttttc ctcaacttta gaaatgattt tactaacctt
     4081 atatccgtaa tacgcgtaac aaacacattc attaataaca atcaacacta agctatatta
     4141 gctttttaaa tgactagggt aaataaaata aggatcaaaa acttttaagt ttctgaccct
     4201 ttccttactt ccgattggtt aatagtgatc ttttgcagaa taaataaata tcgtttcatt
     4261 ttcaactcta tatatcagtc tatgttcatc tgtaattctt ctggaccatt ttccagataa
     4321 atcatgcttt aatggctcag gttttcctaa tccagcaaag ggggaacgat cgatatcttt
     4381 tattaacttg ttaatctttt ttatattgct tttgtttcct tgctcatgcc aataaagata
     4441 atcatcccaa gcatcatcag accaagcctt aatcatcaga ttcaacctcg attaagtcat
     4501 gtgttttaaa tgcacctttg gagaattgtt catctcctcg acgaattttt tccatgacgt
     4561 aattattaga aagtgttctc aacgtttctt gcatagaatc ataatctctt tttgataata
     4621 caacaactgt atcttctaca tctttacttg ttacaataag tgtttcagca tcctcattaa
     4681 cttgtttcat ataactacgt aaattttggc ggaaatttga ataagctact gcttccattc
     4741 ctttcacccc ttatttattt ctataaaaca attgtacatt atattgtaca attaagcaaa
     4801 tgattaatat tctaacttct tataattaaa agtgctatca cttttagttt ttaggataaa
     4861 aagtgacgtc actttttgag tgctggtacc tcaaatcctg ctttttcttg ggcaatcaat
     4921 aaatctaacg caatacacat aatcctggat tcacttttgc cgtacttctg ctttagttgc
     4981 tgcaattctt tttgtctctt ttcatccaac gtaacgggta accgtttatt tcctattgca
     5041 attggcatta gtactctctc ctttcatcga aataacccta tgaaaaatat ggctgcaatc
     5101 atcttgaata gtagactcac aagggctaat acaaagcgcc aaaagatcaa acaaaatacc
     5161 agtattgcca aaaatactac gaagtttaaa tgcacagctg cagcatggcg cataagtatt
     5221 tcgccaacaa ataggactaa caatagagga atgattttat tcatatggat ctccttcttt
     5281 ctcttaggtt atcgggtgtt gcccgcttat ttcgcaccac ctaagcggcg ggggcggttg
     5341 gagcgattgg tgcgaaataa gaaccattcc cttagttact aggttttttg tccttatttc
     5401 acacattctc acttttcggt ataaatgatt attgcctttt tttcctttca aatcgttgat
     5461 atggcattcg tttacggtca agttcatttt ggatttcttc tgtatcgtcg taagtatagg
     5521 tgtctaaaaa atcagttaaa gtcgtgtacc agtcgtcgcc tgggttatct acttcttcta
     5581 catattccct caaaaatgct tcgggtacag cgagttcata atccattccc attaacacga
     5641 tagattccgt tccacacgtc aaaaatctag taaatacaag gtaataatcg tctatcgtcg
     5701 catctttgct gtttagctct tccatttctt cttccattaa ttccatgctc tcaaaaattg
     5761 aataatattc tgattctgag taatagtgtt tcctgcaaat cgtgtagctg acaaagtttt
     5821 cgaccagctc actcctttct aggtaaacat tcatgatgta tttttctgtt tctagtcgta
     5881 gaagctccgt tccttttttt accgtttcag gacgacgttt atacacgtct aaacgattat
     5941 ggctgactgt gaccttcgtt tgactcgttt cactttccaa atacaattgt tcttcgggtt
     6001 ctgttgcaaa gttttaaatc tactatcaaa taaggtagaa taatagaaaa agatagcagg
     6061 aggaatgacg atgaatcatt ttaaaggaaa gcaatttcag caggatgtga ttattgtagc
     6121 cgtgggctac tatcttcgtt ataaccttag ctatcgtgaa gttcaagaaa tcttatatga
     6181 tcgtggcatt aacgtttctc atacgacgat ttatcgttgg gtgcaagaat atggcaaact
     6241 actctatcaa atttggaaaa agaaaaataa aaaatccttt tattcatgga aaatggatga
     6301 aacgtacatc aaaattaaag gaaaatggca ttatttgtat cgagccatcg
//
LOCUS       DARPZF010000092         6287 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.098, whole genome shotgun sequence.
ACCESSION   DARPZF010000092 DARPZF010000000
VERSION     DARPZF010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.098"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..177
                     /locus_tag="SLE65_002676"
     CDS             <1..177
                     /locus_tag="SLE65_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449913.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLNLFNRIVGA"
     gene            190..691
                     /locus_tag="SLE65_002677"
                     /pseudo
     CDS             190..691
                     /locus_tag="SLE65_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
     gene            788..2635
                     /locus_tag="SLE65_002678"
     CDS             788..2635
                     /locus_tag="SLE65_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HEI8449914.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2638..3534
                     /locus_tag="SLE65_002679"
     CDS             2638..3534
                     /locus_tag="SLE65_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEI8449915.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3584..3973
                     /locus_tag="SLE65_002680"
     CDS             3584..3973
                     /locus_tag="SLE65_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEI8449916.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3960..>6287
                     /locus_tag="SLE65_002681"
     CDS             3960..>6287
                     /locus_tag="SLE65_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEI8449917.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         2118 a          933 c         1349 g         1887 t
ORIGIN      
        1 caatctttag tcttactagc gattgtggtc attggtttgt ttttaggatt taaacgcgag
       61 ttttccaaac tgattggctt cttggtgatt gctttgattg cggtaggtct ggtctttaat
      121 gcttctggtg tgaaggatgt cttactcaat ttgtttaacc gaattgtcgg tgcctgaggg
      181 ggaatcacaa tggaacagat acgtgtttat attgcgaacc ttggaaaata caatgaaggt
      241 gagttggtgg ggggcatggt ttaccccacc cgtcgatttt gatgaagtga aagaacggat
      301 tggattaaat gacgaatatg aagagtacgc aattcatgat tatgaactgc cttttgagat
      361 tgatgagtat acaccaattg aggaaattaa tcggttgtgt ggtttagcgg aagagcttaa
      421 aggaacgcca attggtgagg tcgcttcaga gattcaacat gccttcttca attctttcga
      481 ggaaatggta gagcatgtgg atgatatcat ctattatccc gattgtaatg acatgagtga
      541 tgtagcgtat tacttgattg tagaagctgg tgatttaggc gaagtaccag aacacttgaa
      601 gacgtatatt gattttgatg cgtgtggtcg agacttggag attggcggga attatttggt
      661 tacgagtcga ggggtttttg aactaatgta aatcatttgt tagaattgac cagaaatttc
      721 tatcgtactt ttacttttct atttgatata ctgaaataga aaatatttgt tgataggggt
      781 gttactaatg gttggcaata agtggtacaa atgtgatctt catattcatt caactgcgag
      841 tcagtgcttt caggataaaa aggttactgc taaggaatgg gtagaagaat gtttaaacaa
      901 aggactcgat tgtgttgcat taactgatca caatacaggg gaaaatattg atgaatataa
      961 gaaagtggct atcgaaaatg gcttagattt ttttcctgga gtggaattaa cgtgtggaga
     1021 aaatggaact catttactag tcctatttga taaaagtgca tgtacaaatg atatctctga
     1081 tttcttaacc aagatgggta taaaaagaga ggattgggcc agcgctgcag cttgctcaat
     1141 gaaatcagtt ttagaagtta ttgattttgc tgagcacgag ggcttgctcg ttattcctgc
     1201 acatatagat gagtttaatg gaatttcttc agcaaaattt ggaaatctag gaaagatatt
     1261 tgaatcagaa aatatatatg cagtacagac ggttcaaaaa gaattttttg aaaatcgctc
     1321 acaaatgatt ccctcatcta agcgtgacac tatctatgat agtgtgaatg ccagatatga
     1381 tggtagagtt ggaaaagata ctttggaatc ttggtataaa tcagttgttg aggcagaaaa
     1441 aaataatatg acatttctta gcttttctga taacccacac tcgaaaggaa attcaaaaca
     1501 tggactttgg ggaataggca caagatattc ctatataaaa atgaaggacg aacctgactt
     1561 gggatcactt cgcgatgctt taatgctagg cgaaactcga gttcattctg atttttctaa
     1621 tttctccatt aatgaaaatg aagttttatt ggaaaaatta agcttttctg ggaccactct
     1681 tagcacaaaa gaagttgtag tcgaattcag cgataattta acttcaatta ttggaggaag
     1741 aggaacaggc aaatcttgta ttacaagatt cttggtctat gtccttggaa aggaagcaga
     1801 acttgatcaa ttttctgaaa tacaaagtga ttatcagaac tttgcacaaa ttgaacataa
     1861 tggctctgga atatttttga aggatacaat tgtgaaactg aatattttct ataaggggac
     1921 aaaatatcaa ataataagaa cacaggatag acattctatt tatgaattta cacaagagaa
     1981 tggtctggtt gaaaaagaaa cagaacggtt gagaatgatt tccgataagg tgagtatata
     2041 ctctcaaaaa caaatttatg aaatttcaaa aaatcaaact agtatactag aattactaga
     2101 tggatataac tctgatttga tttcagagta taaaaatgag attgaaacat gtgtaaacga
     2161 aataagaaaa ttaaattggg atattgtttc tgtgaaaaaa gaaatacaag ataaggcgaa
     2221 ggtagagctt gaaattgaag atttaaaaaa acaagtagaa aagctatctc ataagagtta
     2281 taaagatgtt tatgatgagt attcaaaaga gacagatatt tatagggaac tgaaacgtga
     2341 tgtggaggca cttaaggaaa ttcccaaaaa tctaactgat agtgttgaca aaattgactt
     2401 tggcaatggt ataaaagtta cagacgaaat tgatgaacac cgcggagaat tgattaagaa
     2461 tttagtgacc aatcgggcta agattcaaac aataattaat gaaatgtcag atgaaattga
     2521 tagttataga gcagagctga ataaatcaga ttggaaagtt aactataatg aggtttcaaa
     2581 gaggtatcaa agaggtatca aaaacttagt gaagagttat ctcaagatga attaaaaatg
     2641 ttacaaaacc ttgattcttt atatcaatct ttatcaaaaa ctgaagagcg attggaagaa
     2701 attattcaac aagaaataaa gcttaaagat taccaagttg aggttgactc agcaatgtca
     2761 agaatgaata aatcatatca aaatctctat tctgagagaa gtagttcctc gcgcgaaatt
     2821 ttttctgata ttacaggaat agaggctact attcaaccaa atagggattt caataattat
     2881 gttaaagagc tcagagcttg tattaataag gaggacactt ttgacagtga gtttggatct
     2941 cttattgata agctgacaaa aaattccatt actaatcaag atatatataa tgacatactt
     3001 gatataagag ttagtgggga aagtagtatt ttttcagata aaaaattaat caattctata
     3061 agaaaattga atgatgcaca agttcttgaa ttacaaaccc ttaagccaaa tgatttagta
     3121 gttatccgac ttgaactaaa tggaaaaaaa gttagtttat cgaatgctag tgctggtcaa
     3181 aagacatctg caattctttc tatgattttg gcgtatggaa attcaccact catattggat
     3241 cagcctgaag atgatttgga tagtcaatta attaataact taatcgtaag aagtatcatt
     3301 acaaaaaagg aaaacagaca aattttaatt gtaactcata atgcaaatat cccagttaat
     3361 ggtgattcag aatggttgat tagcatggga gattcaaaag aaatatcggc tgatcagtgc
     3421 gggtcggtag atgaacccaa tatcaagcca agaatatgta ctgtgatgga aggtggcgag
     3481 gatgctttta caaatagagc gaaacgctat ggttttaaac aaattgtaga ataacactag
     3541 agggtgagac atattattat gtccgccctt tttaggagga aaaatgaaaa aaataaaaag
     3601 ctataccagt atctgggcag ttgaaaaagt catttacgca atcaatgatt ttcagttgcc
     3661 ttttcctgtg acttttaacc aaatggcttg gttcgtttta tctttactgt ttgtcatcgt
     3721 atttgcccat gtgcctccac tatctatgat agaggaggtc tttttaaaat acttaggcat
     3781 accggtggct gtcacttggt ttatgtcgca aaagacgttt gatggcaaga aaccactggg
     3841 atttttacga tcctttatca gctatcactt gcgatttaag gtgacttttg caggaaagaa
     3901 agtcaaagaa cagaagaaac gatgggatga acccagtact cttgtaagga gtgtgaacta
     3961 tgtatccgat taagtatatt gaaaataatc tcgtctttaa ccaagaaggc gagtgttttg
     4021 cctactatga attagtgcct tacaattact cctttttgtc acccgaacag aaatttcaag
     4081 tgcatgataa ctttcgccaa ctaattgcgc aaaatcgtga aggcaagatc catgcgttac
     4141 aaattgccac agaaagtagt attcgcgcca cacaagaacg atcaaaaaaa gaaattaccg
     4201 gtagactcaa agaagtagcg aaacaacgaa ttgatataca gacagaggca ttagtatcca
     4261 tgattggcga tagtcagatt gattatcgct tttttattgg ctttaaacta attgcgacag
     4321 atgaagaagt caatctaaag agtctcaaga aatctttctt ttctgggctt caagaatttg
     4381 tctatggagt gaatcatcat ttgatgggcg attttgtttc cttatccaat gaagaaattc
     4441 gctgctattc taagcttgaa aaattaatgg aaagcaaatt ggctcgaaga tttaaagtca
     4501 ggcgagtcac accgagtgac ctgacgtatt tgattgaaca tatttatggc gaaaaaggga
     4561 taccgtttga agaatacgaa tttcagctac caaagaaaaa gctaaaatca gaaacactgg
     4621 tgaaacgtta tgacttatta cgtccaaatc gttgtttaat tgaagaaaaa ccaaggtgct
     4681 tacggatgga acatgagaat catgagtcgt acgtagcgta tttaacaatt aatacaattg
     4741 tgggggagat ggaatttcct tcctcagaac ttttctatta ccagcaacaa caatttacat
     4801 tcccaatcga cacaagtatg aatgtagaga ttgtgacgaa taaaaaggct ttagctaccg
     4861 ttcgtaataa gaaaaaagaa ctgaaagatt tagacaatca tgcttaccaa tctgacaatg
     4921 aaacgaattc caatgtctta gatgctttgg attccgtgga tgaattggaa accaccttgg
     4981 atcagtcaaa agaatctatg tacaaactga gttatgtggt tcgagtgagt gccgaatcag
     5041 tggatgaact aaagcgacgc tgtgatgaag tgctcgattt ttatgatgat accaatgtaa
     5101 aactagtccg gccctttggc gatatgatgg ggctacatga agaattctta ccctcaagta
     5161 aacgatatat gaacgactat attcagtatg ttacgtctga ttttttggcg gggcttggtt
     5221 ttggggctac tcagatgcta ggagaattag aagggattta ctttggctac aatgtggata
     5281 caggtcgtaa tgtttacctg aaaccggcat tggcttcaca aggagtcaag ggttcagtaa
     5341 ccaatgcgct ggccgccgct ttcctgggtt ctcttggtgg aggtaaatcc tttagtaaca
     5401 atctcttagt ctactatgct gttttgttcg gtggtcaagc tgtgattgtc gatccaaaag
     5461 gggagcgagg agggtggaaa gaaaccttgc cagaaattgc ggatgaaatc agtatcctca
     5521 acttgacgag taagtcagaa aatcaaggtc tgcttgatcc ttatgtgatt atgaagaaaa
     5581 agaaagactc ggaaagttta gcaattgata ttctgacttt tttaacagga atttcaagtc
     5641 gagacgggga gaagtttcct gtgttacgta aagccattcg aacggtgact caaagtgatc
     5701 aacgggggtt attacaagtt attaacgaat tgcgaaaaga cgggtcacca atcgcggaaa
     5761 atatcgccga tcatatcgag tcctttaccg attatgattt tgctcatttg cttttctcag
     5821 acggctcgat tacccaatcg attagtttag ataaacagct aaatatcatt caagtggcgg
     5881 atttggtttt accggatgca gaaacgactt ttgaagaata taccaccatg gaattgctta
     5941 gtgtttcgat gctaatcgtc atttccactt ttgccttgga ctttatccat agtaaccgag
     6001 aaatcttcaa aattgtcgat ttggatgagg cttggagttt tcttcaagtg gctcaaggaa
     6061 aaacgttatc gaataagctt gttcgtgctg gtcgggccat gaatgctggg gtctatttcg
     6121 tcactcaaaa tagcgacgat ttattagatg aacgtttaaa aaataatatc gggttgaagt
     6181 ttgcttttcg cagtaccgat attcatgaaa tcaagaaaac cttggaattc tttggtttgg
     6241 atcaggagga tcaaagcaat caaaaacgcc tgcgagattt ggaaaac
//
LOCUS       DARPZF010000093         6262 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.099, whole genome shotgun sequence.
ACCESSION   DARPZF010000093 DARPZF010000000
VERSION     DARPZF010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.099"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(92..664)
                     /locus_tag="SLE65_002682"
     CDS             complement(92..664)
                     /locus_tag="SLE65_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEI8449918.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(671..1333)
                     /gene="rpe"
                     /locus_tag="SLE65_002683"
     CDS             complement(671..1333)
                     /gene="rpe"
                     /locus_tag="SLE65_002683"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEI8449919.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            complement(1349..1864)
                     /locus_tag="SLE65_002684"
     CDS             complement(1349..1864)
                     /locus_tag="SLE65_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HEI8449920.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            complement(1866..2150)
                     /locus_tag="SLE65_002685"
     CDS             complement(1866..2150)
                     /locus_tag="SLE65_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8449921.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            complement(2184..3512)
                     /locus_tag="SLE65_002686"
     CDS             complement(2184..3512)
                     /locus_tag="SLE65_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEI8449922.1"
                     /translation="MDIVLNAFEWFIGLGSNVFLPLIIFVIGILFGLKPGKAFVSGVT
                     VGIGSIGLGLVLSLLSDGLGTAIQQMGEQYGGGLNILDIGVGVGGPLAYSTSLGILMI
                     PISLILNFIFVVLGWTKTLNVDIWNFWFAIFLGMITQSVTGNFWFGLIGAIVAVILQW
                     FLADRTQKTVSEFFGYPGISITHMMGLSGVLFAKPVNWVFDRIPGFNKIDADAETLTK
                     RFGVLGDTVVIGLIIGIVVGIMAGYDVAGIGNLGIMTAAVMKIMPKMVAMFMEGLMPI
                     AEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMSTSLLLVPISLLLALILPGNKVLPF
                     GDLAFFAFAICLMIPYFKGNIVRSLVGCSLYVVTTLYMATWLAPIITDVFTLASFDVG
                     TAGLVTMLLCGLWPVGLFVLLASYFGVIGIGGLGVVLVGASIYMNKVKKA"
     gene            complement(3526..3981)
                     /locus_tag="SLE65_002687"
     CDS             complement(3526..3981)
                     /locus_tag="SLE65_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEI8449923.1"
                     /translation="MYLDKELCLFQLEVKDQKELFQVMSEQLKNAGCVKDSFLEGITN
                     REQEFPTGLEVNQIGFAIPHTDSAHVNSSQICFASLKEPLVFSDMTDKSHEIPVRLVF
                     MLAMSQPHEQIDTLQNLVSLFQNEEKVNELLACTTKEAFIELVHSAGVY"
     gene            complement(3984..5930)
                     /locus_tag="SLE65_002688"
     CDS             complement(3984..5930)
                     /locus_tag="SLE65_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEI8449924.1"
                     /translation="MIERHVNLLKLLSRQEDFKPASFFSDKLAVSTKTIYQDIELLED
                     YVVNYQVTIERLPSLGIKLIGDRKNVEHLISSVENYLEKDIYSPEKRRVEIIKEVLFG
                     DKPVSLTHLSQSFMVSKTSLYNDLRIINKIIGSGEVKLQSSAEGISFTGNEQAIQRAI
                     KQLVFYYANDMESKTFFQVLNMLFDSKVISVIHDLLFNDYSELTEKVSDYYVRSLIST
                     LVIQCNRLLKGHHLTVEEEFLFNSIRYMETYIVANGLIEELKAKLNLPFYDADKEYLC
                     RQLFAHRVTNNLKTSNEEYAMSVHKLIERMSEIEKIDLTQNDRLYQSLLYHVPAMVLR
                     LKKGIKIQNPLLENIKSQYSELFSIVWYAMSILEEEFDVTLTDDEVSLILIHFQIAIE
                     DQSKANNIIIICQYGISSAQLIYNKVRRFLPAKDNVEISTLDKFHLAEIGEVDLIISS
                     LSFDAGGIPLVRVSPLVSKTDYMNIMEAYTKYLIEEPSRFIQNELIPKAVKVPTISKF
                     VQSSLVKTGVQVESKEECLDLMISELEANSLVTEEFRASIFSREKMGNTNLESGVALP
                     HANPSMVIESNIFIVALKNAINWGDRKVKLVIMVSLAEEDVSEIRGVYEELYQFIGQK
                     EMVDRLLQVHDSEKLLRIFQQKGE"
BASE COUNT         2058 a         1205 c          875 g         2124 t
ORIGIN      
        1 tattaagtta tgtctaatca aataaaaaaa ccattctcat atttgctgaa taattagcat
       61 ttagagaatg gttttttatc tttaaaatct actactcaaa atctgcatgt cgagcaaaca
      121 tcgtttctga gctttcacct gttttatcca ttaaagataa cactaaacta tcaaaggtga
      181 gaaatgctaa ttgttcaaaa cttgaaccca taggttgtga aaaagtatct tcttctcgtt
      241 gattttcatc tttggtaata cctggtaata caagaacaga atctgctaat tgaccaatcg
      301 acgagtcttt tttcatggta actaaagcaa tgcttacacc actttgattt gctttggccg
      361 ctaaattttt taaactacct gtttcacctg agccagaaca gataattaat aaatctccag
      421 gttgcgaatg tggtgaacta atttcaccga caaggctgac tgaaaaacct aaatgcatta
      481 agcgattcgt aaatgcttgc atggcaattc cagagcgtcc tgcaccagct agaaagatgt
      541 gtttagcttg aacaattttc tcactaaatt gttctaactc tacagaatta atacgttttg
      601 agttattttg taattctaag ataatcgctt ctaaatagtt tttattttgg tctttattgg
      661 tcatgatctt ttacttcact tcctctaatg attgatttag tttatcaatt tgttcttgcg
      721 gggtattttt cccattgaag atgaaaccgc ctgatacaaa aatatccgcc cctgctttag
      781 aacaaacttt aatcgtttga ttatcaatct tgccatctac ttcaatatca tacgtataat
      841 cattttgttt gcgtattaca tctaactgtt cgattttaac tactgtctct tgaataaaat
      901 gcttattctc tgttcctgga ttgattgtca ttactaatac ttgatcgact aaagataata
      961 ctggttcaat aaaactgact ggtgttgcag gattaaaagt aatccctact tttgctcctg
     1021 cttccttgac taactgaatg accttcattg cgtgtttggt agcttcaatg tggaaggtaa
     1081 caatatctgc tcctgcttct acaaatcttg tgacaatttt ttctggtgta tcaatcatca
     1141 aatgaacatc aaacacaacg tctgttagtg gacgaatatc tttaataaca cttggtccaa
     1201 aagccatatc tggtacaaaa cagccatcca ttacatcaat atgcaaataa tcaacattct
     1261 tttcttttaa gatttcaaat aactctttaa cttctgcgat aggtgcattt aacaatgatg
     1321 gagcaattgt cattctctat tcccccgttt attctcccat aatcatgaga ttgattgttc
     1381 tagttcgctc tcttagttga tcccaatcga caaaatagac acggcccatt tctcctaata
     1441 aaagtttacc ttcttgaaca attaaagtca ttgagttggt tccataaata gatgaacgta
     1501 aatgtgcatc ggtatttagc atgacccatt tttctgcagg gtaattggga tcagataatc
     1561 ttgttccaaa atcaatgtgt tttggccccg gactgttgta ttgattttca ctcgtcattt
     1621 ttggaataat cgtttccatt acattgttga tgtctacatg taaataatca tcaccaaaaa
     1681 agtttgtgtc atgcatcgtt tcttcaaaaa agagtgagca agttgtatgc gggctcgaaa
     1741 ttactaacat tccattctca atacctgctg tatcaactgt atctaaaagt tcttttcgaa
     1801 tatcatgata cgaaggacgc cctgaaactg tttcaatagt caaagtgtca tgatgaaaac
     1861 gcatattaaa cacctaatct ttcttttaca tctgcataaa tggcatctgt accaatacct
     1921 gttaataagc ccaagccatt cgttacttta gctttaatta catcagggac aattgttgta
     1981 cttactacag catcatattc atcaatttta tttagctcat cagcaatttt agattgataa
     2041 attttcactt gatctgttaa tccttcttct tccaaccatt ttgataattt tgctactgca
     2101 attgtagaag tagcatgacc tgctccacaa ataactaata attttttcat attgatctct
     2161 tctttcttat tttaatttta tgattaagct ttcttcactt tgttcatgta gatagaagca
     2221 cctactaaaa caactcctaa tccacctatt ccaattacac caaagtaaga tgctaataaa
     2281 acaaacaacc ctactggcca taatccacat aacaacatag ttactaatcc tgctgtcccc
     2341 acatcgaaac ttgctaatgt aaacacatca gtgataattg gtgccaacca tgttgccata
     2401 tataatgttg taacaacata caacgaacat cctactaatg atctcacaat atttccttta
     2461 aaataaggaa tcattaaaca gatggcgaaa gcaaagaatg ctaaatctcc aaaaggtaat
     2521 actttatttc ctggaagaat tagtgctagc aataatgaga ttggtacaag caatagagaa
     2581 gttgacataa tagttggatg acccacagtt aacgctgcat ccattccaat gtttacttgg
     2641 cgaccattta actttttatt cgtaaattct ttcgccgctt ctgcaattgg cattaaacct
     2701 tccataaaca ttgctaccat tttaggcata atcttcatca ctgccgcagt cataattcct
     2761 aagtttccaa ttcctgctac gtcatagcct gccataatac ccactacaat accgataatt
     2821 aggccaataa caactgtgtc acctaaaaca ccgaaacgtt ttgttaatgt ttctgcatct
     2881 gcatctattt tattaaatcc aggaatacga tcaaaaaccc aatttactgg tttggcaaat
     2941 agtactcctg ataatcccat catatgtgtg atagagattc ctggatagcc gaaaaattcg
     3001 ctaacagttt tttgtgtacg atctgctaag aaccattgta aaattactgc gacaatcgcg
     3061 ccaattaagc caaaccaaaa gtttcccgta acagattgag taatcatacc taggaaaatt
     3121 gcgaaccaaa agttccaaat atcaacattc aatgtttttg tccaacccaa aaccacaaat
     3181 atgaagttaa gaattaatga aattggaatc attaaaattc ccaatgatgt agagtaagcc
     3241 aaaggtccac caacacctac gccaatatct aggatattca ggccaccacc gtattgttcc
     3301 cccatttgtt gaattgctgt tcctaaacca tctgataata aacttaaaac taatcctaaa
     3361 ccaatagaac cgataccaac agtaacgccg gaaacaaatg ctttaccagg ttttaatcca
     3421 aataatatcc cgattacaaa aataatcagt ggtaaaaaga cgtttgaccc taatccaata
     3481 aaccattcaa aggcatttaa tacaatatcc atctctctat tcctcctaat aaactcctgc
     3541 agaatgtact aactcaataa atgcttcttt cgtggtacat gcaagtaatt catttacttt
     3601 ttcttcattt tgaaataggc taactaagtt ttgtagtgta tcaatttgtt catgaggttg
     3661 tgacattgcc aacataaaga ctaaacgtac aggtatttca tgagatttat ctgtcatatc
     3721 tgaaaatacc agtggttcct ttaatgaggc aaaacagatt tgagagctat ttacatgtgc
     3781 ggaatctgta tgtgggatag caaacccaat ttgatttact tctaatccag ttggaaattc
     3841 ttgttcacgg ttggtgatac cttctaagaa actatctttc acgcaaccag cgttttttaa
     3901 ttgttcagac attacttgaa acaattcttt ttgatctttc acttctaatt gaaataaaca
     3961 taattcttta tctagataca tttttattct cctttttgtt gaaaaattct tagtaatttt
     4021 tcgctatcat gaacttgtaa caagcgatcg accatttctt tttgcccaat aaattggtaa
     4081 agttcttcat atactcctct aatctcagat acatcttctt cagctaaact aaccataatg
     4141 actaatttga cttttcgatc gccccaatta atcgcatttt ttaatgctac aataaaaatg
     4201 ttggattcaa tgaccattga tggattcgca tgcggtaaag caacaccact ttctaaatta
     4261 gtattcccca ttttctctct agagaagata gaagcacgaa actcttcagt aactaatgaa
     4321 ttggcttcta gttcggaaat catcaaatcc aaacattctt ctttgctttc cacctgtact
     4381 cctgttttta ctaaagatga ttgaacaaat ttagatatgg tgggaacttt aaccgcttta
     4441 ggaatcagtt cattttgaat aaatcgcgaa ggttcttcta ttaaatattt agtataagct
     4501 tccataatat tcatataatc tgttttactt accaatggag atacccttac taagggtata
     4561 ccacctgcat caaaggaaag agaggaaata atcaaatcaa cttccccaat ttcagctaaa
     4621 tgaaacttat ctaaagttga tatttctaca ttatcttttg ctggtaaaaa ccgtcgaact
     4681 ttattgtaaa ttaattgcgc agaagaaata ccgtattggc aaataatgat gatattattt
     4741 gctttggact gatcttcaat agcaatctga aaatgaatca aaattaagga aacttcatcg
     4801 tccgttaaag tcacatcaaa ttcttcttca aggatggaca tggcgtacca tactatgcta
     4861 aagagttctg aatattgaga tttgatattt tctaataacg gattttgaat tttaatacct
     4921 ttttttaaac gaaggaccat tgctggcaca tgatacaata aggattgata taatcgatca
     4981 ttttgagtca aatcaatttt ttcaatctca ctcattcttt caatcaattt atgaacgctc
     5041 atagcgtact cttcattgct ggtttttaaa ttatttgtca cacgatgtgc aaatagttga
     5101 cgacatagat attctttatc tgcgtcataa aatggaagat tcaattttgc cttcaattct
     5161 tcaattaaac catttgccac aatgtacgtt tccatatagc gaatgctatt gaagaggaat
     5221 tcttcttcaa cagttaaatg atgacctttc agtaaacggt tacattggat aactaaagta
     5281 gaaatcaatg accgaacata gtaatcagaa accttttcag tcagttcact gtaatcattg
     5341 aatagcaaat catgaatgac actaataact tttgaatcaa acaacatatt taaaacttga
     5401 aaaaatgttt ttgattccat gtcattcgca taatagaata caagttgctt gattgctcgt
     5461 tgaattgctt gttcattacc agtaaaacta attccttctg cagatgactg caacttaact
     5521 tctccactgc caataatttt attgataatt ctcaggtcat tgtataacga tgttttacta
     5581 accataaaac tttgagacaa atgagttaaa gaaacaggct tatcaccaaa caaaacttct
     5641 ttaatgatct cgacacgtct tttttctgga gaataaatat ctttttcaag ataattttct
     5701 accgatgaaa tcaaatgttc aacgtttttc ctatcaccta tgagtttgat acccaaagaa
     5761 ggtaatcgct caattgttac ttggtaatta actacataat cttccaacaa ttcaatatct
     5821 tgataaatgg tcttggtcga cactgccaat ttatcactaa aaaaagaagc gggtttaaag
     5881 tcttcttgtc gacttaataa ttttaataaa tttacatgtc tttcaatcaa acttgttcac
     5941 ctcttaacgc tagcatttgt tacctctttt cattatttat tctagcactg gaaccccctt
     6001 ccctcaatta catctatgtc aataatactt gtggaagttt gttgtaaagg aaatccaaat
     6061 aatcttaaaa aatgagaaac aaaaaaggag aaatccttaa aagagctaag atattccaat
     6121 agaaaatact ccttattatg gaagtaatat gaaatattac aattgaaaaa taaaaacaat
     6181 ataatggcgt cactaaaatt cgtatttttt tattataata taacttaatt acaaatgctc
     6241 atctatgaac aattgagtcc ta
//
LOCUS       DARPZF010000094         6207 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.100, whole genome shotgun sequence.
ACCESSION   DARPZF010000094 DARPZF010000000
VERSION     DARPZF010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.100"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            191..709
                     /locus_tag="SLE65_002689"
     CDS             191..709
                     /locus_tag="SLE65_002689"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEI8449925.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            837..1520
                     /locus_tag="SLE65_002690"
     CDS             837..1520
                     /locus_tag="SLE65_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEI8449926.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1829..1902
                     /locus_tag="SLE65_002691"
     tRNA            1829..1902
                     /locus_tag="SLE65_002691"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1863..1865,aa:Arg,seq:tct)
     gene            2061..2420
                     /locus_tag="SLE65_002692"
     CDS             2061..2420
                     /locus_tag="SLE65_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HEI8449927.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2543..4174
                     /locus_tag="SLE65_002693"
     CDS             2543..4174
                     /locus_tag="SLE65_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HEI8449928.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4236..4877)
                     /locus_tag="SLE65_002694"
     CDS             complement(4236..4877)
                     /locus_tag="SLE65_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEI8449929.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    5063..5139
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5159..5467
                     /gene="rplU"
                     /locus_tag="SLE65_002695"
     CDS             5159..5467
                     /gene="rplU"
                     /locus_tag="SLE65_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEI8449930.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5494..5838
                     /locus_tag="SLE65_002696"
     CDS             5494..5838
                     /locus_tag="SLE65_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEI8449931.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5851..6144
                     /gene="rpmA"
                     /locus_tag="SLE65_002697"
     CDS             5851..6144
                     /gene="rpmA"
                     /locus_tag="SLE65_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEI8449932.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
BASE COUNT         1955 a         1023 c         1313 g         1916 t
ORIGIN      
        1 ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat aaaaaatgag
       61 ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca tttttacagc
      121 tataatttga aaaaaattta tcgttattat atgattaaga aggattgaat aaagaaagaa
      181 gttgaaaacg atacctgatt acaaaaaaat aacttttata agttctataa cgttgattat
      241 atttttaatt cttattcttc tcgtcgtctt ggttccccga atttttggtt tgactcctta
      301 tattattgag gacaaagaaa tgagtccata ttatgcacaa ggaaatctga tatatgtacg
      361 accgaaaaat acaaatgaga ttttagtcgg agatattatt acatattatg aaaattcagg
      421 aaaaaaaatc tcgacgcgtc gcgtaatagc cgttgaaaac aaccacgaag atttttatac
      481 aaaagctgat acaaagactt atattgagcc tggagtagta aaaaagagaa atattatcgg
      541 tagtcccatc tttcagattc catatattgg actagtcctt tcaaaaacgg catttgcatg
      601 gattcagggg ttattcttta cgattgcttt ttgcctaaca ggaatcacag catggaatac
      661 ctttgtagag ttgaaaaaga agcggagacg aacacagaaa tttttgtaag aatgttaaaa
      721 acataaatgt attccagaga tccaacgact cttctgaaca tgaaacacga gaaaacactc
      781 atgcagcttg tagatttagt cagttgttcg tataatgtgt gaagaggagg agtagtatgc
      841 gcaatgaaat gatgcatcgt cctgtagtca aagaagaact attggatttt atgcgtaccc
      901 agcaaaaaaa attaccgggt gagctaggca aactggaaga agaagctcat gtagcagaag
      961 taccagttat tccccatgaa acagttgtat ttttgaaatt tttacttgga cagcttcagc
     1021 ctgaacgaat cttggagatc ggagcagcta tcggtttttc atcaagtgtc atggccacga
     1081 caatcggaga aaacgctcat gttacgacaa ttgatcgttt cgatgtcatg atcgagaaag
     1141 ctaaaaaaaa ctatgaacgt ctaggactga cagataaagt gactttgctt gaaggtcaag
     1201 cagcagatat cttgccggag ttgtctggtc cgtatgactt tatttttatg gatagtgcaa
     1261 aatcaaaata tattgaattt ttacctgaat gcttacgttt gttaagaaaa ggtggcgttt
     1321 tgatggtaga tgacatcttc caaggaggaa cgatcttgct cccagatgaa gagattcccc
     1381 gtggcaaacg agctatccat cgtaaattaa atgaatttct tcgtgttgtg atggatcatc
     1441 ccgatttgac atcgacaatc ttgccattag gtgatggtgt gatcttaatg acaaaggaat
     1501 cagaaacaat cgagttgtga tacatgatta tggcagcctg tagataatcg attgaatcga
     1561 gggctcaatt cgaacttgat gtaaaagttt ctatatttgt aagtcaatta aaggatacag
     1621 gaaatctaaa taaacaggag tagcatgaag tcaatgtagc tcctgttttc aattgataac
     1681 cttagaacag ctgaaggaga atgtctcgtt ttaaaagatt gatttagtag ttgggccaaa
     1741 ataattcatt atttgctaat taaataacta tttcgtattg acagaagcaa tttaattatc
     1801 tataattatt gatgttccgc tgattcttgt catagtagct cagctggata gagcatccgc
     1861 cttctaagcg gacggtcggg ggttcgaatc cctcctgtga cgctaaaaaa ccgttagaaa
     1921 ctgaggtttc taacggtttt tctttgtttt ttgtgccaat attgtttgtt ttcaaaggca
     1981 aataaaataa aaaaacatcc ttatcgagta caattataag gagcaaaaaa ataaaactca
     2041 tcagaaaaga ggaagaagat atgacgatac tatctagaat tttagtgact ctagttgcaa
     2101 ttgaattttt ttatatcatg tatatcgaaa cggtgagaac tgattctgac acgacaagta
     2161 gggtttttaa aatgagtaaa gaagagttaa gcagaaaatc tgttcaaaca ttgtttaaga
     2221 accaaggagt gtacaatgga ctattaggag tgggactact ttatggagct tatctttctt
     2281 ccgcatctaa agaaatcaca agtatgctat taatatctat tttttttgtt gcattatatg
     2341 gcagtttgac tagcgatcgt tggattttac tcaaacaagg tgggctagct ctgttggcat
     2401 tgctttctat tttcttataa atatagaaaa aataagaatt tatctaacag gaaactttgt
     2461 gaaaaatatt actttatctc atgaaatatg atattctaat gaatggtatt ttagaaaatt
     2521 tcatgaaaaa ggagttagat aggtgttcaa aaattatgtt tcctcactaa aaaaagaatt
     2581 ttcaggttat gatctttcaa gatttcagaa agatcttttg gctgggatca cagtagctgc
     2641 tgtagcattg cctttagcct tggcttttgg ggtatcaagc ggagctgatg cggccgcagg
     2701 tttgattacg gctatcattg ccggtatcgt tattggcggt ttatcaggcg gtttttatca
     2761 aatatcaggt ccgacaggtg cgatggcagc tatcttgatg tctattgcgg caacaaaggg
     2821 aatgcaaggt gtattgcttg ctactttttt agcgggtcta tttttacttg cagcaggact
     2881 tttccgatta ggaacactga cttcttttat cccagcaccc gtaattacgg ggtttacttc
     2941 aggtattgct atcattattg cattaggtca gatcgataat ttatttggtg ttcactcgga
     3001 aggtacaaac gttattgaaa aactaagtag ttatcaaacg ataggatttc cgataaacac
     3061 agcctctttg atcatgggag ggctagtcat tttagggatg tttatctatc caaaaaaatg
     3121 ggcgaaacga atgcctagtt cgctgctggc tatcattttg gcaacagcag ttatgctatt
     3181 gttccattta ccagtagcaa ctgtgggtaa gattccacaa acattgatca gtagtaatcg
     3241 tttgaatatg ggagatttta gcttttctgc cttgcaacaa gtggcagttc cagctattag
     3301 cattgcttta ttaggaatga ttgaaagctt gctatgtggt gcttcggctg gccgaatggc
     3361 aaataagccc ttagatagca atcaagaatt aatggcgcaa ggaattggaa atctgttgct
     3421 tcctttcttt ggcgggattc ctgctactgc ggccatcgcc cgtacaagcg tggccatcaa
     3481 atctggtgca caaactagat tagctggtat gatacatgca gttgtcttac tgctctccat
     3541 gcttgttttt gcgccagtga tgtcacagat tccaatgcca gcacttgcag gtgttttgat
     3601 tgtgacggct tggcgtatga atgaatggga aacgatcaag gagctattta ctaataaata
     3661 ttggtcagca gttctattgt ttatccttac gatgatttgt acagttatct ttgatttaag
     3721 tattgctatc gtgatcgggg tgatcggcgg ctgtgtattt tttgttgtca aaagcgctgc
     3781 tatcacgatt tcattagaaa cgatcgattg gcaaagaatg gggctgccag aaacggaaaa
     3841 gctgaataac tggacagtag tgtatattag tggtccactg ttttttatgt cttcagaaaa
     3901 actcaaaaat aaattggaag aactaaatca tcacgatggt gtcattttct ccatgcgagg
     3961 cgtaccaagt attgatttga cggcacgtgc agtttttgat gaatttcaag aaaaagcaga
     4021 gcaaagagga caaacgatta tctatacttc cttgcagcca gaagtagaaa aacaactttc
     4081 tcacttgtgg gaacatacat tcacgcatca acatcaaaca gttgctcatg cgttgacagc
     4141 tttacatgcg aaatatactg caattagcca ttaaaacaat gaaaaagaac agacaagact
     4201 gtaaactgaa gattttatgg tcttgtctgt tctttttaat attgctgtaa aagtgaagct
     4261 agtacttgcc agtcttgatg gataacaggt acaagggagc gattgtagaa aatagctgct
     4321 ggatgaaaaa gtggaagaat tcgatagttt ttttctgacc attcgtaggc atccttttgt
     4381 tctgttaatt gtaagacagg ccctgtatag agttgaccat gatttttggt aaccgtatat
     4441 tctttgccaa gtaaacgttg aagaccaatg tttccaagtg tcgcaattaa ttttggctgg
     4501 accttcatca gttcgtaatc caatattggt gcatgcgcaa atacttcgga acgagtaggt
     4561 gtccgatttg gataaacagt ttctgactgt tgtgtccgtt tattgatccg atgagtcacg
     4621 cgatacgggc ggctccttac agcactggtg atatacacct cttctcgtgt taagccagtt
     4681 gaagaaagtg cctgcatcaa ttcttttcca gcttgaccgc taaaaggaac atgcgtatca
     4741 atctctgttt tccctggggc ttctcccacg agcatcagtt taggatgaag aggtccttgc
     4801 ccagcgataa atccttctac aggacggccg ttcattctta aagaagcttc ttgtatcagt
     4861 tcttttgggt attccattta tgctcctcct ttttctttta ttataagaat aaaagaaaca
     4921 caatgcgact attttatttg gtagaactgt gaggatagaa aagcagaagt attgcttgaa
     4981 tttttgtttt actttttgat tttaaattta gttgactaac ggttgctgtt ctggtaagct
     5041 agtactgttg taattgtgga ctccacagct acaaccgctc agaacaagta ataagcacag
     5101 catatgctgt cacttcggat ggcgagtcta agtatatcag aaggaggtgc tttatagcat
     5161 gtacgcaatt attaaaactg gtggtaaaca agtaaaagtt gaagtgggac aagcaatcta
     5221 tgttgaaaaa cttgacgttg aagcaggaga aaaagttgtt tttgacgaag ttatcttagt
     5281 aggcggagaa tctacaaaag taggcgctcc aactgttgca ggtgcaactg ttgaaggtac
     5341 tgttgaaaaa cacggcaaac aaaagaaagt cgttactttc aaatacaaac ctaaaaaaca
     5401 ttcacaccgt aaacaaggtc atcgtcaacc atatacaaaa gtggttatcg acgcgatcaa
     5461 cgcttaatag cgtttgagaa agaaggccta tatatgatca aaggaacatt taagcgaaat
     5521 gacgcaggtc agatcgtttc attcactttg accgggcatg ctgatgctgg tccttatgga
     5581 agtgatatcg tttgtgcggg tgtttctgcg ttagcgatca gcactgtcaa cgggattgcc
     5641 tcattagccg gttttgagcc gattgttgaa atgaatgaag aagaaggcgg ttatctttat
     5701 accgaagtca cttcaggaat gacacaagaa caaaacaata ttgctgagat tctattagaa
     5761 aatcttttat taggattaca atcgatagaa gctgaaaact cagaatatat ccaaattaaa
     5821 acaattaatg ataaatagga ggtgcagacc atgttgttat ctatgaatct acaattattt
     5881 gcccacaaaa aaggtggcgg ttctacatct aacggccgtg actcagaatc aaaacgtcta
     5941 ggtgctaaac gtgctgatgg acaaacagtt acaggtggat caattcttta ccgtcaacgc
     6001 ggtacaaaaa tctatccagg tgtaaacgtg ggtatcggtg gagacgacac tttatttgca
     6061 aaagttgatg gcgtagtacg tttcgaacgt aaaggccgta acaaaaaaca agtgtctgtt
     6121 tatccagtag ctcaagaagc ttaattgaat cttatgatta aagaggttgt gacaagactt
     6181 ttgtcacagc cttttttgtt tataaaa
//
LOCUS       DARPZF010000095         6068 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.101, whole genome shotgun sequence.
ACCESSION   DARPZF010000095 DARPZF010000000
VERSION     DARPZF010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.101"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            832..1566
                     /locus_tag="SLE65_002698"
     CDS             832..1566
                     /locus_tag="SLE65_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8449933.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1582..2751
                     /locus_tag="SLE65_002699"
     CDS             1582..2751
                     /locus_tag="SLE65_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEI8449934.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2767..3762
                     /gene="lacD"
                     /locus_tag="SLE65_002700"
     CDS             2767..3762
                     /gene="lacD"
                     /locus_tag="SLE65_002700"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEI8449935.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3841..4767
                     /locus_tag="SLE65_002701"
     CDS             3841..4767
                     /locus_tag="SLE65_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEI8449936.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4786..6036
                     /locus_tag="SLE65_002702"
     CDS             4786..6036
                     /locus_tag="SLE65_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8449937.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         2026 a          997 c         1247 g         1798 t
ORIGIN      
        1 attggcgcag cgaatccttg ataatgagct cggatgtgct aacgctagcg aggcagtcta
       61 actttaactg ttagctcctg ccgaagatcg tcacatccga ggaggctcat tgtcaaggac
      121 aatcggaata gcatacggaa agaagttctg caccttataa aatttgtcaa aaaaactgtt
      181 gccattccaa agtttgaaaa atgctatttc gaggtagaag gatattatat aagcacggtt
      241 gactaaacga agtgataata aaaaaagtta ttcaagaata agaaaaatta tgatacgaat
      301 tcagataaac tggagaatac agagaccttt aaaagggata agaaacaaca taaattcctc
      361 ttaagagaga acgaaaggac aaagccagca acttgataca cgagctagta ttagaggaat
      421 ttattctcat agactccctt ttgaatacgt ttcaacttta attttcatgt tcataaatga
      481 tttgaaacca aagcaaatgc gttgcacttt tcctccgtct tccgaaaatc gttcaattca
      541 ctggtaagta gtcatttgat agtttgaggc aaattgttga ttgatgaagg gtaggagcta
      601 aaaaaagata ccagttgaag agagaaaaag aaaaaaatag agggtgttct tgaatgaaaa
      661 aagttggaaa attatttttc atttcctttt attcctatta aagtcagtga tgtcaatcat
      721 attaacaaga ctaaaaatga aaataaaaaa aagattgttc ttagtattga ctcataaaaa
      781 ataccactac tatacttaca ttgtggttat agccagttag gagagacatc gatgcaaaat
      841 acctttcaat caaaatcact ttattatcag ctggtagaaa tattgaaaca acgaatcgaa
      901 aacagtatgg tcgctcatga caagctgcca tcagaaagag agttgaccag tttttatggc
      961 gttagtcgca cgacggtgcg actagcattg caagaactgg aaaaaatggg ctacatttat
     1021 cgacaacatg gaaaaggaac ctttgtttcg gaattaagga caaatgcgac tgatctagct
     1081 ggcgcatata gttttaccga acaaatgcgg gcaatgggca aacatcctga aaccaagata
     1141 ttggccttca agaagattga agcaactaaa tatttagcga gtcatctgaa tgttcaacta
     1201 ggtgagcctt tatttcaatt agaccgattg cgcttagctg atgatttgcc aatgatgatc
     1261 gagaaatcct atttgccagt gaagctattt atgtcccttt ctcaagaaat tctatttctg
     1321 aaacctttat ataatttgtt ttcagagaat ttcaatcaaa tcgtacggtt ggctgacgag
     1381 gaattttatg ccagcattgt ccagaaagaa gatagtgagt tgctaaatat tccagaagga
     1441 tcaccagtgc tccatttagt tcgctcaacc tataatctcg agaacgaagt gattgaattt
     1501 acattaagtg tagcgcgggc tgataaattt cattataaga tcaggcatct gcgttccact
     1561 aactgaattg gaggaaagaa aatgtttatg ttctcaaaag aagaactacg aaagctagga
     1621 gcagaaaata ctacccgaga aattcgacag caaccggaac tgtggcatga gacgtttgac
     1681 cgttatcaag aaacagttgc agatttagat cgtttgttta cggatgcgaa acaacatgct
     1741 ggagagcgac caatccgagt catttttaca ggggccggaa cctcgcaata tgtgggagat
     1801 acactaattc cgtttcttac tagtcaagga aatacgaacc agtttatttt tcaaagtatt
     1861 ggttcgaccg atatcgttgc tacgccaaaa gaatacctga ttcctgatga gacaacgatc
     1921 ttggtctcat ttgcccgtag tggaaatagt ccagaaagtc tagccgcagt taagatggcc
     1981 aatcagctgg tcaacaagat ctatcatatc gtgatcacct gtgcaccaga cggattattg
     2041 gctacacaaa tgcctacaaa aaaagaaaat ctagttttac taatgccaaa caaagccaat
     2101 gacgctggtt ttgctatgac aagcagtttc agctgtatga cgctgactgc gctacttatt
     2161 tttgatcaag caagcaatca gcaaaaagaa agatatgttc atcaattaag ccgactagga
     2221 gaagaagtca tccaacgaga atcagagatc caagggtatc tggcatcaga ctttcatcgc
     2281 atcatttact taggttcggg aagcttaggc ggattgacta gagaagcgca attaaaagtt
     2341 ctcgagttaa ctgctggaaa aatcgcaacc gtatttgata catctttagg attcagacat
     2401 ggtcccaaat cttttgtcaa tgagcaaaca ttggttttcc tgtttgtcag caatgactca
     2461 tatacgcaga aatacgatgt agacatgctg gaagaaatca aaaatgacgg tattgcccaa
     2521 cgcgttgttg gaattggtca aaagggttca ttgtttagtg gtgattcctt tgaattagtt
     2581 gcagattcgt tactgccgga tggctatctt gctttagcag atatcatggt agcccaaacg
     2641 atcgcattac tttgttcggt gaaggttggt aatacaccag atacaccatc gccaagtgga
     2701 acagtcaatc gtgtggtcaa aggcgtaacg atttatccat atgaaaaata ggaaagagtg
     2761 tgaagcatgt tagaatggtc ggaaaataaa agacaagcaa tggaacgtct atcgacgcca
     2821 gaaggcatta ttaccgcttt ggcgatcgat cagcgaggcg cgctgaagaa aatgatgtcg
     2881 gctttaggga tggaagcgac aaaggaaaaa attgagcagt ttaaaacact aatttcccaa
     2941 gaattgactc cttatgcctc agcaatttta ttggatcctg aatacggact gcctgctgca
     3001 cagaagcgtg cagcagcgag cggtctgctg ttggcatatg aaaaaactgg ttatgatcaa
     3061 accgtacccg gccgcttgcc ggatctgctg tcggactgtt cagttctgcg attgaaagag
     3121 ttaggtgcgg atgcggtgaa atttttactg tattacgatt atgaagaagc agaggaaatc
     3181 aatcggcaaa agcaagtttt tgttgaacga attggaagcg aatgcatggc tgaaggactg
     3241 ccattttatt tagagttatt gtcatatgat gctaaaaatg tagatacgaa atcgctttcc
     3301 tatgccaaag caaaaccgcg caaagtgatc gaaatgatga aagaattctc gaaaacccag
     3361 tataaagtag atgtcttaaa ggttgaagta ccagtaaaca tgtcatttgt tgaaggaaat
     3421 gcaacagggg agatcgccta tacacgtcaa gaagctgccg cttattttaa agaacaaagc
     3481 gatgcaacag atttgccgta tatcttctta agtgctgggg tatcagcggc attattcatg
     3541 gagacattgc gttttgccaa acatgctggg gcacgattca acggtgtact ctgtggcaga
     3601 gcaacttgga aagatgcagt cgctcctttc gttgaaaaag gagaagcggc aactttagaa
     3661 tggctgacag aacaagggac acaaaacatt cgtcaattga atgaagtgat aagagaaact
     3721 gccatcccat ggtatgagaa agtaagtgaa agcacttgtt aatgtttcta atatattagt
     3781 agtgataaga gatatgtgtg attataattt atcattattg aaactgggag gatattttat
     3841 atgaataaaa gattgttaga ttattcagct tcagattttt tgaaagctaa gccgatggaa
     3901 ttaaagcagg caattttggc ttctgaaggt agaacaatta tggcagaaaa tgtgccaagt
     3961 agctgtcctt acatgggaaa atcagtgaca aatgcagaat tggagagagc tgctggagct
     4021 gatttaattt tgtttaatgc actagatctt tttaatcctc aaatttcagg tgtaccttta
     4081 actctaaaag agaatccaat aatctggatt aaaaaagctt taggaagagc tattggtgta
     4141 aatttagaac ctgtagacaa agaagttttg atgagtgaaa atcgaactga aatttcaagt
     4201 ggtagaatcg tttctcctga gactttaaaa aaggcaaatg aattaggctt taattttatt
     4261 tgtttaactg gaaatccagg aacaggagta tctaatagaa ctattgagaa agcaataaca
     4321 ttatccaaat caatttttaa tggattaatt atcgctggaa aaatgcatgg tgctggtgtt
     4381 gatgaaccaa ttatgaactt agatatagca aaaagattta ttaaaacagg tgtagatatt
     4441 ttattagttc ctgctccata cactgttccg tatttcatgg aaagtgattt gcgaggaatc
     4501 gttgattata taaaagattt taatagaaat aaatctattg aggaaaaagt tctagtacta
     4561 acggctaatg gaacaagcca agactcttct gaccaagaaa ctattaaaaa aattgcatta
     4621 gcatcaaaag catgtggagc tgatattcaa cacatagggg attctttaaa tggtatttgt
     4681 cttccagaaa atatttttgc tttgggtcaa gcaattcggg gatatcgtca tcaaattatt
     4741 atgttaggaa aatctaatta tcgttaatta aggaggaaat gaaagatgat cgacaaagtt
     4801 caaaaaatag ctgcaaaaat tagtaatcaa agacatctac tagctttaag agacagcatg
     4861 gctgcagtta tgccattaat cattattggt tcctttttta tgttattagc aaatttcccg
     4921 atagaaggat ttacaaaatg gttatctgaa attggagtac aatccttttt gaacaaagca
     4981 tcagattcaa catttggtat tattggatta gctgttacct actctttggg acacaatcta
     5041 gcaaagactt atggtgtaga ctcattatca gcaggattat tatctttgag tggatatgtt
     5101 ttacttacac ctttattgga tgcagatggt tctataggat ttccaacaaa atactttggt
     5161 acctcgggtc tttttgttgg tattattgta gcacttgtat ctacagaaat tttccggtgg
     5221 tttgtactta aaaatattac aattaaaatg ccggcaagcg ttccaccaaa tgtaagccga
     5281 gctttcgttg ctattattcc tggctttttt gtcgttctac tatggtttat tgttgttgta
     5341 atttgttata aacttggaat tgaaaatgtt catgctctta ttgcagatac actcgcaaaa
     5401 ccactatctt tactgacgaa aactttacca ggaattatat tggttatact tattcaatgt
     5461 ttcttttgga tgtttggtat tcatggtgca caggtaacgg ggccaataat tgaaccgtta
     5521 ttattgcaaa actctgatgt aaatagaatt gcttatcaag ctggaaaaga acttcctaac
     5581 attataactt atgaattctt atataacttt gttttttctg gtggtgcagg ttgtttattt
     5641 gcacttgcca ttttaacatt tttcttttca aagagtcagg aaaataaaac tttaggtaag
     5701 ttatcaatcg ctccagtaag ttttcaagta gcagagcccc ttctatttgg gtttccaact
     5761 atattaaata taaaaatgtt aattccattt gtaactgcac cagtagtaac aacattaatt
     5821 acttattttt caatgagtat gggattagtt gcaaaacctg taggagcaac aatcccatgg
     5881 acaactccac cgataattgc cggattttta gcttctggtg gacgaataag tggtgcagtg
     5941 attcaagtaa taacaattgc aataaatgtt ttgatatact atccattctt taaattagat
     6001 gataatgcca agctaaaaag cgaaaaaaat gattagaact acctatatgt ttctaactgt
     6061 agttaagt
//
LOCUS       DARPZF010000096         5885 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.102, whole genome shotgun sequence.
ACCESSION   DARPZF010000096 DARPZF010000000
VERSION     DARPZF010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5885
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.102"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            58..597
                     /locus_tag="SLE65_002703"
     CDS             58..597
                     /locus_tag="SLE65_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEI8449938.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            671..1111
                     /locus_tag="SLE65_002704"
     CDS             671..1111
                     /locus_tag="SLE65_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEI8449939.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            1124..1333
                     /gene="copZ"
                     /locus_tag="SLE65_002705"
     CDS             1124..1333
                     /gene="copZ"
                     /locus_tag="SLE65_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HEI8449940.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            1333..3519
                     /locus_tag="SLE65_002706"
     CDS             1333..3519
                     /locus_tag="SLE65_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEI8449941.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            3539..5710
                     /gene="copB"
                     /locus_tag="SLE65_002707"
     CDS             3539..5710
                     /gene="copB"
                     /locus_tag="SLE65_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HEI8449942.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
BASE COUNT         2014 a         1027 c         1320 g         1524 t
ORIGIN      
        1 tgcggcgtta taagtggtat gatcgaacca aattccaaag agaagtgagg gagaagaatg
       61 aagatcatcg tgattggaca aagtgggtcg ggaaaatcga ccctcgcaag gaagatcaaa
      121 gaaatcaccg actttccgct actgccgcta gaccttttat ggcatacaac agactacagt
      181 attcaggcaa aaaagtggtt tttgcaagaa cagcaatcgt ttatggtatc taatccgtca
      241 tggattgttg aaggaaatta tacttctaca ttagaggaaa ggattaaaga agcagataag
      301 atcatttggc ttaaagtgcc gcgttatctc gccatctacc gagtagtttg gcgttctcta
      361 aaaagaaaga taaacaaaaa atctcggcca gatatgcctg aatcattttc agagaaacta
      421 aacagggaat acttagaatt tttatctttt atctggcatt ttgaagaaaa caatgaaccg
      481 aaaatacagc agctgatcca agtagctaat gcaagaaata aactgatcat ccttaaaaca
      541 agacgagaga aacaagaatt tttaactaaa ttgaaaatag agagcaaaaa taattgacag
      601 tttttgttta caagcgtaat ctgtattcat aagctaatga ttacatttgt aaacgaaagg
      661 tgtgaaataa atggaaaaag tcaaaacgcc agtaaagatc agtgattcag agtgggagat
      721 catgcgtgtt atttggacac ttggacagac gacagcccaa gaaatcacgc agatcttagc
      781 tgattcgatg gattggaaac cagcaacgat caaaactttg ctgggacgtt tggtaaaaaa
      841 agaagtgatc tggacagaac aagaaggaaa aaaattcatt tatcatccag ctgtctcgga
      901 gatggaaaca gttcgcagtg cgacggaaaa tcttttttcc catatctgtg caaaaaggat
      961 tggagagacg attgcggatc tagtagaaga agccactttg actcaagaag atatcaatga
     1021 gattttgaaa caactggaac aaaagcaacc agtagatacg atcgaatgta actgtatccc
     1081 aggtcaatgt gaatgtaaac aacatcaata ggaggaagaa aaaatgaaac aacaattttc
     1141 aatcgaaggt atgagctgca atcattgtgc agcaagagta gaagaaacag taagcgcact
     1201 tgacggcgtg caaaaagtga aagtaaattt gaaaaaagca aacggtacgg tcaagtttga
     1261 tgaaacaaaa gttcaatccg aaaagatttg tcaagcaatc aatggattgg gttataaagc
     1321 agaggtgatt tgatggcaac agcagaaacc aaaatggata cgttcgtcat tacaggtatg
     1381 acttgtgcaa attgttctgc taggatcgaa aaagagctga acggacaacc tggtgtggtc
     1441 aatgccacag tcaacttggc cactgaaaaa gcaagtgtca aatatgaagg gacgaccact
     1501 gaaaaattaa tccaaagcgt agaaaacatc ggttatggtg caattttgta cgatgaagcc
     1561 cacaaacaaa aaattgcaga agaaaagcaa gcgtatttga aaaaaatgct attcgatctt
     1621 atattgagta cggttttgac tttgccgttg atgttgtcaa tgattgctat gatgttagga
     1681 agccatgcgg cgattgttca cttttttcat tttccaatcg tccagttagt gctgtctgct
     1741 cctgtccaat tttatgtcgg tgctcgtttt tataaaggtg cgtaccatgc aatcaagacg
     1801 aaagcaccaa atatggatgt attggtagca attggaacat cggctgcctt tgcattgagc
     1861 atttacaacg gatttttccg tggacacccc caagatcttt attttgaaag cagcagtatg
     1921 atcatcacgc tgattttgct cggcaaatat ttggaacata cagcaaaaac gaaaacaggt
     1981 aatgcaatca aacaattgat gtctcttcaa acaaaaaccg cccaagtgat aagaaacggg
     2041 aaagaagaaa cgttagcgat tgaagaagta gtcgttggtg atcaactagt catccgtcct
     2101 ggtgagcaga ttccagcaga tggtcgaatt atttcaggaa gcagtgcgat agatgaaagt
     2161 atgcttactg gtgaaaatct tcctgtagaa aagaatccgg atgacacgct ttttggcggg
     2221 acaatcaata cgaatggtct gctacacatg gaagtcacac aagtcggcaa gcagacagta
     2281 ttagcgcaaa tcattcaaat ggtggaagat gctcaaggga gcaaagcccc aatccaaaaa
     2341 atcgcagatc ggatctcagg gatttttgtt ccgatcgtat tagtcatcgc gtttatcacg
     2401 ctcatagcta caggtttgat cactggtgat tggcaactcg cattgatcca tagtgtctct
     2461 gtattagtca ttgcgtgtcc atgtgcatta ggtttagcga ccccaacagc tattatggta
     2521 ggaacgggtg ttggtgcacg aaatggaatt ttaattaaag gcggagaagc attagaagca
     2581 gctgctcact tagacagcat tgttttggat aaaactggaa cgattacaga aggaaagccc
     2641 aaagttacag atctagtcgg ttcaaaagaa gtcctatcta ttttttatac tttagaacaa
     2701 gcttctgaac atccactagg taaagcaatc gtggaatacg gaaaactgca agaagcagca
     2761 acatacgata tgattgattt tacagcccac ccaggtgctg ggatcagcgg tacgattaat
     2821 ggagtacgct attttgcggg tacacgtaaa cgattaattg aattgaacct atcatttgat
     2881 gaataccaag aacacgcgtt agaattagaa cagcagggaa aaacagtcat gtttttagct
     2941 gatgaaaagc aagtgatcgg gtggattgcc gtggctgatc aaatcaaact agaagccaaa
     3001 caagcaatca agcagctcca gaataaagga ttagatgttt ttatgctgac aggagacaac
     3061 aaactggcag ccgaaacgat tggtaaacaa gttggtattg atccaaagca tatctttgct
     3121 gaagtacttc cagaggataa agcagcctac gtagaaaaac ttcagaaaga tggcaaaaaa
     3181 gtcggtatgg caggcgatgg aatcaatgat gcaccggcct tagcattagc tgatgtcggt
     3241 atggcaatgg gaagtggaac ggacattgcg atggaaacag ccgatgtgac gctgatgaat
     3301 agcagtttgg catccattgc acaaacaatc gagttgtcta ggttgacatt gagaaaaatc
     3361 aaacaaaatc ttttctgggc ttttgtctat aatacgattg gtattccttt tgccgcacta
     3421 ggctttttga atccaatcat tgcaggagga gcgatggcgt ttagttccgt cagtgtattg
     3481 ttgaactccc tgagcttaaa tcgacacatg aaaaagtaag agaagggatg gagtaaaaat
     3541 gaatgggaac gatatggaga aaaaacatga gcataaaaaa gaagtagtaa acaaagaaag
     3601 tacagaatct catgaaaaac agatggagat gaaacatgac catagtcaga tggatcattc
     3661 catgcacatg ggacataacc atggagatat agcaaacagc aaacaaatgg accattcgat
     3721 gcacatggat cacgaacacg gcggcatgga tcattccatg cacatgggga atttcaaaca
     3781 aaaattttgg ctatcgctta tcctagctat cccaatcatt cttttttcac caatgatggg
     3841 aatggaattt ccatttcaag taacgtttcc tggttctgat tggctcgtat tgatcttagc
     3901 aactatacta tttatctatg gcggtcagcc atttttaagt ggagctaaga tggaattgaa
     3961 acaaaaaagt cctgctatga tgacactgat cgcgatgggg attacagttg catatattta
     4021 tagtgtctat tcgtttatcg caaatctgct caatccacat acacacgtca tggatttctt
     4081 ctgggaattg gctactttga tcgttattat gctactaggt cactggattg aaatgaatgc
     4141 tgtgtcgaat gccagcaatg ctttacaaaa actagcagaa ttactgccag aatcagtgaa
     4201 acgcttgacg aaagatggaa aagaagagac agtttcattg aaagaagtaa acgaaggtga
     4261 tcgtttgatc gtccggtctg gtgataaaat gccaacagat ggtgtaatct tgaaaggtga
     4321 aacaattgtt gacgaatcag ctgtgactgg cgaatcaaga ggaatcaaaa aacaagccaa
     4381 tgacaaagtg attggcggtt ctatcaatgg ggatggaacg atcgaaatcg aagtaactgg
     4441 aactggtgaa aatggttatc tagcgaaggt tatggaaatg gtgcgaaaag cacaaggaga
     4501 aaaatccaag ctagagtcat tatctgacaa agtggcaaaa tggctgtttt atgtcgcatt
     4561 aattgtgggt atcctggcat tcatcgcctg gttgttcttg acagatcttc ctaatgcatt
     4621 agaacgtatg gtaacagtct ttatcatcgc ctgtcctcat gctctaggtt tagctatccc
     4681 attagttgtt gctcgctcca catcaatagc agctaaaaac ggattacttt tgaaaaaccg
     4741 caatgcactg gagcaagcca atgatctaga tgtgatcatg ctggacaaaa caggaacact
     4801 aacagaagga aaatttactg taacgggtgt cgaagtactt gatgatgcgt tcaataaaaa
     4861 tgaaatcctt caatatctag gagccttgga agcgaatgcc aatcatccat tggctgttgg
     4921 cattatgaat tatttgaaag aacatgaaat caagccttat caagctgaaa atctaaaaaa
     4981 tctttcagga gtcgggctag aggcaacagt caaaaaacaa caagtgaaaa tagttaatga
     5041 aaaagaagtt gagcgtctcg gattaaacgt agaacaagca ttattgaaac cttaccaaga
     5101 acaaggaaat accatcagct tcctgatttt agaaaatcat ctagctgcaa tcgttgcttt
     5161 aggtgacgta gtaaaaacag aagcaaaaga atttatccga acattgaaag aaagaaaaat
     5221 cactcctgtc atgcttactg gtgacaataa aaacgctgcc caagcagtag cagattattt
     5281 agggatcgaa gaatattatg gcggtttatt accagatgat aaagaagctg ttgtccagaa
     5341 ataccttgac caagggaaaa aagtaatcat ggtgggtgat gggatcaatg atgcgccaag
     5401 tttagcccgt gcttcaatcg ggatggcaat cggtgcaggg acagatatcg caatcgattc
     5461 tgcggatgtc gtattgacaa acagcgatcc aaaagatatt ttgcattttc ttgatctagc
     5521 caagcaaacg cgaaagaaaa tgatccagaa cctctggtgg ggggcaggtt acaatattct
     5581 tgcaattccg ctagcagccg gaattcttgc gccaattggt atcatattaa gtccagcagt
     5641 tggtgctgtc ttgatgtcgt taagtacggt agttgtagct ctaaatgctt tgacattgaa
     5701 aatcaaataa taatgaaaaa aggggctctt tgtcaataag gactgatggg ttgtacaaaa
     5761 tcaaatctgg gtcagaatga acctcattct ggctcagatt ttttgttatc ttactttgat
     5821 taattgattg atcaaaaaga ttctaattct catgttctca aatgatttaa atccgtagga
     5881 tactc
//
LOCUS       DARPZF010000097         5849 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.103, whole genome shotgun sequence.
ACCESSION   DARPZF010000097 DARPZF010000000
VERSION     DARPZF010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5849
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.103"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(460..1089)
                     /gene="udk"
                     /locus_tag="SLE65_002708"
     CDS             complement(460..1089)
                     /gene="udk"
                     /locus_tag="SLE65_002708"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEI8449943.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1173..1868)
                     /locus_tag="SLE65_002709"
     CDS             complement(1173..1868)
                     /locus_tag="SLE65_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEI8449944.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1881..2597)
                     /locus_tag="SLE65_002710"
     CDS             complement(1881..2597)
                     /locus_tag="SLE65_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HEI8449945.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2927..3532
                     /locus_tag="SLE65_002711"
     CDS             2927..3532
                     /locus_tag="SLE65_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HEI8449946.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3857..4180
                     /locus_tag="SLE65_002712"
     CDS             3857..4180
                     /locus_tag="SLE65_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEI8449947.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4362..5732
                     /locus_tag="SLE65_002713"
     CDS             4362..5732
                     /locus_tag="SLE65_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEI8449948.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
BASE COUNT         1666 a         1153 c         1095 g         1935 t
ORIGIN      
        1 agggggtgcg acaaaagagc ttcttcaaaa aaataagtcg aaatctcaca caaattcgag
       61 aaataatttt cgtaagtttc ttcttattta ttgcatctga ccacttctgt tacaacctct
      121 cgttaaacgg tgttcaaaag cttgcatcta cgataataag cccaacccaa cgaaaaacgt
      181 gaggagctgt tttatttgga tgctcttatc gcttgatgca aagacagctt ttttacaacc
      241 tctacttcac ggtgctcaat cagctgacct tcggtattag ctcaaaaaac ggtaaaatat
      301 aaacagctat tttccgtttc ttctttttaa tacttaggtc aagatgctgt tttcacaacc
      361 tcttgttata aataaaaaaa cagttggctg gtgactgttc aaaaagcaga atccttgctt
      421 ttcaaacggt cgcagtccgt tcaactgttt cgctgcgcac tatttatggt ttaagaaact
      481 agctactttt gttgtaatca aatcaatagc aacgtggttt tctccgcctt ctggaacaat
      541 gatatccgca tagcgcttcg ttggttcgat aaattgatga tacatcggtt taacaactgt
      601 caaatattgt tcgatcacgg agtccaatgt gcgtccccgt tcttccatat cccgtttgat
      661 acgacgaatg atacgaatgt catcatctgt atctacgtat actttgatat ccatcaagtc
      721 acgcagacgt tcgtcttcta aaatcaggat tccttctaga atgatcactt cttttggttc
      781 ctgaatgatc gttgcctgac ttcttgtatg cgctacatag tcatacacgg gtttttcaat
      841 ggctttatag ttcagtaagt cgcctacatg ctgaatcagc agatcattat caaaggcaaa
      901 tgggtgatcg taatttgtgt tcaatcgttc ttcaaaactc aaatggctct gatccttgta
      961 ataagaatct tgttcaagca tcatgatgga atggtccggg aagttgttga aaatcgcacg
     1021 gctgacactt gtctttccgc ttccggatcc acccgtcaca ccaatgataa ttggcttgct
     1081 ttttgtcatt gactaaaacc tctttcgtat ccgttttttc attctaatct attatagcga
     1141 aaaaacacga aaatgctata tttttctgaa aattaatcct tttcaatttc caataatgaa
     1201 taaagttcct ctaatgaatc gattcgataa gtaggctgga tttcttcgat ttctggtaat
     1261 ttatttctat tgaaccaaat cgtatcgatc cctgccatat ttcctccttt gatatcagaa
     1321 gtcaaagaat caccaatgat cacagtttgc tttttatcaa aattaggaat gtgggaaaag
     1381 acatgatcaa aaaattcttt catcggcttt tgcgctccga cagcttctga gacaaagata
     1441 tccttgaagt aatcaagcat tcctgcatct gttaatcgcc gatgttgcgt gtgcgacaca
     1501 ccgttcgtca caatataaag atcagcatgc ggatggacct ttttcaggat ttctagactt
     1561 cctggaacaa gatcatgacc ttggttcaag tagtggcggt agcgtttttc catttgatca
     1621 ctatctactg ttttcccaaa ttgctggaaa agtaacccaa aacgactgcc tattatttct
     1681 tctcgtgata gtctgccttt ttcaaactcc tgccataaat gatgattcaa agccttatag
     1741 ctggtttcga tttctggtgt caatgtgatt ccttgttctg caaacaaagc acttaaagca
     1801 ttggcttcag ttaattgaaa atctaacaat gtatcatcta catcgaacaa taaagtttta
     1861 tatttcatct ttttgacctc ctatttaaaa taaatactta actttttcat ctctgctaat
     1921 gtcaacgatc gatactcgcc tactcctagc tgttcatcta attccaatgg tcccatgctt
     1981 agccgtttca atgcggtcac tttctttcct tgggctaaga acatcttttt gacttgatgg
     2041 aattttcctt cttggatcgt caataaaacc gtactttggt gcttgtctgc tttgagtatt
     2101 tttaaatcag ccggcttaca ttgataccca tcagcgaata cgattccatt ttcaaatgct
     2161 gttacgtctg ccggtgtcac cctttcgttc acaactactt gataagtctt tgaaaccttt
     2221 ttttctggaa gtagcatttc atatcccaat tgtccattcg aagtgatcag caatagtcct
     2281 gttgtatctc tatctagtct tcccactgga tataatggtt ggaaacgatc ggcacttgca
     2341 atcagatcga ttactgtcgt cttttctgga tctgatacag ctgtaacagc tttttcaggt
     2401 ttattgagaa gataatagga ctcatttgtt tctaagtgtt cacctgctac ttcgatttga
     2461 tgcagtaaac tatctacatt tcgattttgt cgaaattcga ctgtgccatc tatcatcact
     2521 tgcttcaaag caaacagccg cttcatttcc ttgcgtgtcg tttctaattt ttcttctatt
     2581 aatttatcta aacgcatgct gtttcctttc ttattactac taattaatta taccttgaat
     2641 attcttgctt gcaaatacat catcatagtt attccttgac ttaattaaca gttcacgtta
     2701 cggttaaata gtaaagtgaa ttggatttct catacacagc gtaatgacct ggtggagaaa
     2761 agttgaatcc tgactttcta aggggagatg cgcgcatctc tccttttgcg cttttttaag
     2821 cgccctgcct tcgatgatgt gcacgagatt agcctttaga attcacttaa ataaaatctg
     2881 tccgttacca aagcagacag tcacatttta aggaggaatt ttggttatgt cagtatcatt
     2941 agaagtaagt aaaagagaag tacgtccccg ttcattaaga aacaaacttc gtcacgaagg
     3001 gaaagttcca gctgttgttt atgggtataa agtagaaagt acccctatct cattcgatgg
     3061 tttgacacta agcaaattgt tgcgtgaaca tggagcgaac acagtcatca cgatggacat
     3121 cgatggacaa aaagtcaata cattggttca caagatccaa acgaacactt ttaccaatca
     3181 tttcgaacat gcagaatttc tatctgtaaa catgtcggaa gaaacagaag tcgaaacaga
     3241 agtcgttctt gttggcgaat cagtgggtgc taaatctggt ggagtgttag ctcaaaactt
     3301 gtatacagta gtcgtatctg ctacaccaga caaattgcct gaacgaattg aagttgacgt
     3361 gacaaacttg gaattaggtg attctattac agtagccgat cttccaaaaa acgacgatta
     3421 caaattcgtg accgacagtg aagagcaaat cgctgctgta gtcgctcaaa gtgaagaaga
     3481 aagcacaggt gaaggtggcg aaccagaagt gatcggttca acagaagaat aatactgaaa
     3541 caatcaggtg gtgttagaag cggcgggtca gcagctttta acacgccttt tttatttcta
     3601 atcgtttatt ttcatatggg gcttccactt ttgtaaatgg ctttacaaac gaaaaatcct
     3661 aatttaccaa gcttttcctc gcatactttt atcgtacctt tataaaaatt tatactttga
     3721 aaaaaagtat tcaattattg ttgcattttt cctgattctt tattagaatg aaccctcgtt
     3781 gaagtaagta tttctagttt atcctaggat taattataaa aataaaacat tcgttgattc
     3841 gaaggaggtt aaacagatgt ttgaaagttt tgatagcagc cgcaaccgtt acgcttcagt
     3901 tggtgtcgta tcaagtttgc cagatgaatt gattgacagt atatggttta ttattgacct
     3961 agatcttaag ggagtcattc cattagaaaa tatattaacc tttgatttga tcgaaaatcg
     4021 tggaaaagtg acgatgcatt tttctcaagc aggaagcaat gtggaaatgg atattgattt
     4081 gccgtttgcc tattcgaacc aatttcctgc tcaagtatac gcctatgatg acggtacgag
     4141 agaaacgatc cttttaccaa gtgagattag acaatattaa ggtgatagat aaacgtggat
     4201 gtcccttatt ttacagacca ggccaagttg ttgattcttt gactcaattc ttggcttctt
     4261 tttatggagt ttcataaatt atcattgatt tctaattggt attctcagga taaacgctat
     4321 atactactaa ctaaatttta aagatataag gagtttaaaa gatgcgcgat ttaacaaaag
     4381 gaagccccgc taaactgatt ttgatgttca ctgttccttt actgatcgga aatgtttttc
     4441 agcagttcta caatatgatc gatatgatca tcgtgggtca gacgctaggt aaaaatgcgc
     4501 tggcagcggt tggtgcaact ggaagcctga catttttgat cattggcttt gcccaaggtt
     4561 taacagctgg tttagccatt attaccgcac aacgttacgg tgcaaaagat tatcggggtc
     4621 tgaagaaaag ttttgctgct agtgttgtca ttagtcttgt cgtcactgtg attttaactg
     4681 tcctaagtct cctgtttatt cgtccgatgc ttcaattgat gcaaactcct cctgaaatac
     4741 ttgatcaagc acaaacattt atttcaatta ttttattagg gatctttgca tcagtcagtt
     4801 tcaatttgct ttctaatgtc attcgcgcac ttggtgacag ccgcacacca ctattctttc
     4861 tgatcattgc ggtcatcatc aacgtcgtac ttgatttgat ctttattatc tattttggca
     4921 tgggtgtgga aggtgcagct attgctacag taatcgcaca agtttcttcc agcgtactgt
     4981 gtctagtgta tatcaagaaa aaaatgcctt tgttacagtt acgcaaaaaa gatttcaaat
     5041 ttgaaaaaga agagtttgct gtacacctaa atgctgcttt gccaatggcg tttcaatctt
     5101 cgatcatcgc tgttggtgct atcgtgttac aagcagcact aaatagtcta gggacagatg
     5161 tcgtagctgc tcaagccgct gctggtcgta tcgaccaatt tgcaaatcag ccgatgatgt
     5221 catttggtat tgcaatggca actttcactg cacaaaacta tggtgcgaaa gaatatggcc
     5281 gaatcttgca aggggtacgt caaactttac tgatgagtgt cggatttagt ctcttagcag
     5341 gtgctatcgt cattttcttc ggtcatttct ttgttcaatt gtttgttagc ccatcagaaa
     5401 cacgtgtatt tgaattagca caaacctact tcaatatcaa tgggtctctt tactggatct
     5461 tagcagtcct gttcatttta cgctacacac ttcaagggct tggacaaagc aagatcccta
     5521 cgatcgccgg tatgatggaa ttgcttatgc gttcttttgc agctatcgtt cttacaggaa
     5581 tgtggggata cccaggagca gcagcagctt ctcctttagc ttggatcggt tctgttgccg
     5641 tgttgcttta ctcttatatg cgttcgatga aacaattgaa acacatgggt gaagaggaac
     5701 atttcacatt agaacatgca gaagcaagat agccttgatt aaaagaaatc gttgcggcta
     5761 aaaatgaaaa cttttattga aaatatcttc ttcgtttacc gaaaacaggt tttttagata
     5821 acaaaaaggc tgtgacaaaa aatgtcaca
//
LOCUS       DARPZF010000098         5501 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.104, whole genome shotgun sequence.
ACCESSION   DARPZF010000098 DARPZF010000000
VERSION     DARPZF010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5501
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.104"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            153..1142
                     /locus_tag="SLE65_002714"
     CDS             153..1142
                     /locus_tag="SLE65_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEI8449949.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1124..1585
                     /locus_tag="SLE65_002715"
     CDS             1124..1585
                     /locus_tag="SLE65_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEI8449950.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1635..2099
                     /locus_tag="SLE65_002716"
     CDS             1635..2099
                     /locus_tag="SLE65_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8449951.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2113..2862
                     /locus_tag="SLE65_002717"
     CDS             2113..2862
                     /locus_tag="SLE65_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8449952.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2862..3692
                     /locus_tag="SLE65_002718"
     CDS             2862..3692
                     /locus_tag="SLE65_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEI8449953.1"
                     /translation="MENSTEKKRLITKKDLHKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTPFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3692..4339
                     /locus_tag="SLE65_002719"
     CDS             3692..4339
                     /locus_tag="SLE65_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEI8449954.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4437..5213)
                     /locus_tag="SLE65_002720"
     CDS             complement(4437..5213)
                     /locus_tag="SLE65_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8449955.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLTESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            5295..5438
                     /locus_tag="SLE65_002721"
                     /pseudo
     CDS             5295..5438
                     /locus_tag="SLE65_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608918.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
BASE COUNT         1882 a          747 c          979 g         1893 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctggcatttt attatataaa attgttataa
       61 aaaatttttt ttgaaaaata gtattgcaaa ataaagcaat ttcatagata ataggtatcg
      121 taaagttata taactttata atacctatta gagtgaggga taaagaaatg agacaactac
      181 acaaagaaca gattgaaaca gcaatggcag cgttaaagga aaagacaatt gatcatgtat
      241 attttacagc atgtgggggt tcacaagccg ttttaatggc tggtcaatat ctatttgata
      301 aagaattaac tgtaccttgt catgtttata ctgctaacga atttaactat gctataccaa
      361 aaggattatc tgaaaattct ttagttatca cttgttccca ttctggcaca acaccagaaa
      421 ctgtagaagc aacaaaaaaa gcaagagaat ttggagcaat gactatttgt ttatctaatg
      481 aagaaggatc tcctctatgg gaagcagctg aatatcctgt tcactatgat tggggtaaag
      541 atgttgatgc tagtgattta aataaaggaa ttctttatgg tttattattt aatattttac
      601 ttgttttaga tggctctaaa aaatgggaaa cttgcttgaa tgaatttgat aagttaaatg
      661 atcttgttat tgctgaaaag agcaaatttg aaataactgc taaagaatgg ggtaaaaacc
      721 aaaaacgaga taaaattatt tacacaattg gtagcggtat taattacgga gaaatttact
      781 ccacagcagc ttgctggttc atggaaatgc aatggattaa ttctaatgct attcattctg
      841 gggaattttt ccatggtcct tttgaaatca ctgattatga tgtaccattc atcttagtga
      901 aaagtattgg agatacaaga tttttagatc aacgggtaga agacttcact aaaaaattca
      961 gtaataaatt aatggtttta gaccaagctg attttgactt agaatctata gatagtgtag
     1021 cgaaagaata tattgcagct gtacttagtg gcgttgttat tcgccaaatg gtagaagcga
     1081 ttgcttttga aagaggccat tccttagatg ttagacgcta tatgtggcaa atgaaatatt
     1141 aattaatagg aggttgcaaa agatggcaaa tcaattattt cacattgtga ttacaacaca
     1201 ttctaccctt tgtgagggtt atttaaaggc aacaaaatta attttaatga atgacgccac
     1261 aggtattagt gctgttccat ttaaagaaaa tactagtcca gatgattttg aggagagtat
     1321 gaaagaaata attagtcagc atcatttgca acctctaatt attttaacgg atttaattgg
     1381 aggaacacct aataatgttt ctattaaaca gttgaacaac aatagaattc aaattattgc
     1441 tgggattaat ttacctcttt tactggagtt attaatggcc cagtcagctg gtaaatctat
     1501 agaagaaata gattttaagg aattactgaa taactctcaa aaaagtatgg ttcatattaa
     1561 ttcgctttta aaagatgtca gttaaggtgg caatttctat tctataaatt ttaaaaattg
     1621 aaggaggaaa tagaatgatt aaattagtgc gtgtagacca cagattactt catggacaag
     1681 taatattttc ttggactaaa cagtatgata ttaaccatat tattgtggct gataacaaag
     1741 ttccaggaga tccaatgtct gtgatggctt tgacaattgc taaacctgct gattgcaaat
     1801 tagacattgt taaaattagt gatgttaaag ggattatgga aacatcccca aatgataatt
     1861 acatgatttt aattaaagga cctaaggaag cttttgaatt agttcaaaat ttaccagaaa
     1921 ttaaagaaat taattttggc ggtgtgtcta agaaaagcga gtccaaacaa tatggaaagg
     1981 cagtcttttt aactcctgaa gaattagaag ccacaaaaaa aattcttgat caagaagtga
     2041 aaatatttgt gcaacaagtc ccatcttcaa gtattgaaaa tgtagatttt agtaagtaag
     2101 gggggaaaat aaatgttatt aaaagccatt ttattaggtt tagttggtgt ggtagctgtt
     2161 attgactcca ggttaattgg tcgacaaaat attggtagac cactaatttt gagtacactt
     2221 gccggacttg tgctaggtga cttgcataca gggattgttc ttggggcatc tttagaatta
     2281 atttctatgg gattcgtctc aattggggcg gctggacctc ctaatatgca acttggtagt
     2341 attattgcca ctgcttttgc aattttaact aatagtagta cagaaacagc cttaacaata
     2401 gctatcccag tggctgtagc tggtgaattt atgagtatta tcatgcgtat gataattgct
     2461 caatttggac atgctgcaga taaagccatt gaaaataata aatttagaaa agctcaaatt
     2521 attcatattt attggtcatt tatttttaat gcttttgttt actttattcc aatcttttta
     2581 acagtatatt ttggtgctga cgttgtggca gatttagtag ataaaattcc agaaatgatt
     2641 acagacgcct tgactgtctc tggaaatatg ctttccgcat tagggtttgc aatgctatta
     2701 agcacaatgt tgagtaaaaa attatatcct tactttattt ttggattctt tattgttgcc
     2761 tattcaggtc tttcactaat tggcgtgaca atttttgcag ctctgattgc ctttgtaatg
     2821 gatcaagtta aatatggaaa aagagaagag gcgcatggtt aatggaaaat agtacagaaa
     2881 aaaaacgttt aatcacaaaa aaagatcttc ataagatgtg tcttcgttca tggacaatca
     2941 tgtgttcgtg gaattatgaa agacaaatgc atatgggatt tatgtatggg atggcgccaa
     3001 ttttaaataa agtttataaa aatgatgaag agaaaaaaag agaagcttat actcgtcata
     3061 tggcattttt taactgtacg cctcaaatga ctccatttat tatgggactt tgtgcttcta
     3121 tggaagaaca aaatgctcaa gcagaagaag gaaactttaa tactgaatct atctccatga
     3181 ttaaaaccag tttaatgggt ccttttgctg gaattggtga ttcatttttc caaggtactt
     3241 taagaattat tacatttggg attggattgt cttttgctaa gcaaggtagt attttaggac
     3301 cgattttagc tgttggcctt tttgctatac cttctatttt agctgttttt tacggcggta
     3361 aattaggata tgagtctggc aataaatacc ttactaaatt gtatcaagaa ggtcttatgg
     3421 atcgagtaat gcaatttgct tctatcattg gtttggctgt agtaggtgga atggtggcta
     3481 gcatggtgcc aattgtcacc cctttaaaat tcactacagg gggaacagaa cttgttttac
     3541 aagacttact tgattccatt attcctggat tattaccact tgtatgtact ttgggaatat
     3601 ataaattgat taagaaaaat gttagtacaa atatgctctt attaggttgt attttggcag
     3661 ggtttgtttt aagtataata ggtatcttat aatgattaag gctctaattt ttgatatgga
     3721 cggagtttta attgatagcg agattatgta tcaaaagtgg gtatttaatt ttttaaaaca
     3781 agaaaattta agctatcctt tgtattctta tcaaaaaaag attggaacta cagcaagtat
     3841 ttttgatgat atagaaaagt acaatgaggg atgtaacagt ttagaattga agggaaaatt
     3901 tactaaatat tggaaatcgc aaaagattga ttacttggat atttttccta atatactaat
     3961 tgaacagctt gaatggttaa aaaagaaaaa aataaaaatg gcaattgctt cttccagtcc
     4021 aatggatact ataaatgaag ttgttaccac ttgtaaaata gagtcatatt ttgattgttt
     4081 aattagcgga agagatttgc cagaaagtaa acctaatcct actatattcc ttaaagcttc
     4141 agaacagctc agaattccag ttgaagaatg tctggtgata gaagattctt ataatggtat
     4201 aaaagctggt aaaagagcaa atatgaaggt tcttgcaatt aaagataaac gtttttctca
     4261 agatgtaagt ctagcagatg atgttattta cgatattaaa tatctgcgac aagaagtaca
     4321 ggtgaaattt ggaatataaa taagtttttt gatgtattta gagaatatta gtaaaaataa
     4381 aaatcatgcc caaatctaat caaaattgat tgctttgggt atgatttctt ttaatatcaa
     4441 tctattactt taggatctga atcattttta tgcaccgtat ctaaagtgat attttctgtg
     4501 acttcaataa cataactaat tctatcacaa cgaactgtgg attgagaata atgaaatggt
     4561 tgattatttt tatctttgcc aaccttttct aaaataaata gcggatctcc tactatacat
     4621 tgcaataagt cggaaagctc aggtgttgca gataaaccgt ttatttccat aatagagctc
     4681 gtagctttga catcatagtc atcttctaga agtttatata atgaagtata ttggctacct
     4741 ttttcaaata aagttggaaa tttttcttct gatgcgaaaa aattatcaat tcccatcggg
     4801 gcaccgtctt cccacattaa acgtttaata ttgtaaactc tatcagttac attgatttgt
     4861 aatttattag ctaaaaactc atcagccttt ataattttag aatgtaaaac agtatatcta
     4921 attttatgtc ctcgggtaga aagagaatcg ctaaatccat gaactccagc taattttaaa
     4981 ctttcttttt tttgagttac aaaggtccct ttccccctta atcgttcaac tgttccactt
     5041 tctgttaaaa gtttaaaagc ttttcgaatg gtaatcttac ttactccata aattttacat
     5101 aattcttctt ctgtaggtaa ttgctctcct ggaagatatt ttttttcacg aatatcgtta
     5161 cgtatagaag cttctacttg tagatataat ggtctattat cttgaaaatt catagtacac
     5221 tccctaaaaa gttatacttc attatatcac aatttattaa aataaaagat taagatataa
     5281 atataaatga actagtcttt gactaaccaa tgcccgcttt tgaaagaaaa caaattcatt
     5341 ctgttttaag taaaaatcct tatgttacca ctcattctga aggggatgag ccttatcgct
     5401 acttggttgt ggaaccaagc gataagacaa ttttataaat tcaatattaa ttaaaataaa
     5461 aacaaacaaa gtagattatt ttactttgtt tgttttttta t
//
LOCUS       DARPZF010000099         5343 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.105, whole genome shotgun sequence.
ACCESSION   DARPZF010000099 DARPZF010000000
VERSION     DARPZF010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5343
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.105"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(133..453)
                     /locus_tag="SLE65_002722"
     CDS             complement(133..453)
                     /locus_tag="SLE65_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEI8449956.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(601..2835)
                     /locus_tag="SLE65_002723"
     CDS             complement(601..2835)
                     /locus_tag="SLE65_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEI8449957.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQKAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            3314..3580
                     /locus_tag="SLE65_002724"
     CDS             3314..3580
                     /locus_tag="SLE65_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEI8449958.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            3580..5307
                     /gene="ptsP"
                     /locus_tag="SLE65_002725"
     CDS             3580..5307
                     /gene="ptsP"
                     /locus_tag="SLE65_002725"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEI8449959.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
BASE COUNT         1612 a         1001 c         1069 g         1661 t
ORIGIN      
        1 tgaatcaaaa aacatctaaa gtagaaaagg aattctacct tagatgttct tatctcactc
       61 tatcagtcct atttgacaaa gagcctcttt acttttgtcc cacgctcttt aattattatg
      121 ttcaaaattt gtttacacgg ctaatgtagc gcctaattca tgttttggaa tcgagatttc
      181 aacaaggcct gccaattcga ttactttgat ttcatcctcg tggtaaacgg cgtctttgat
      241 tttatctaag aaataatttt tagcatcttc gatttctttc ggctggattt tacgtttgtc
      301 attgatcagc agaatttcat tatgttcagg ggcttcagtg tagacaatag tggtatttcc
      361 ggctgtgtag accttgacta gatgggcatc agtgttttca agctggttta atacaagacg
      421 ggaatggctg tttgttacat ttaccaattt catggcgctc acctctttta tgtattttta
      481 attgcttgtt tctcttatta taatttcttt tttataaaat gaacagtatt ttgacttttc
      541 tgaaaaaaga atgagacggc atttctcaaa gaaataccgt ctcacgctat aaaactggat
      601 ttattcagcc gtttcttcgg ctgattcttt agccaaacgt tctggtttag aagtaacgat
      661 gatttttcca tctttatcca gttttgcttt caactcatgg atagaagggt gatcaagata
      721 aaattcagcg ataccatctt cgatttgttc ttggatcgtg cgtcgaagag gacgagcacc
      781 catagatgga tcatagccta agtcaactaa tttttctttg acattcgtag gaacttcgat
      841 gtgaagttgc tgtgctgcca gcatttggtt gacatcgtct agcattagtg tgacgattgt
      901 catcaagttt tcttttgata atgcactgaa ttcgatgatc ccgtcaaaac ggttcagaaa
      961 ttctggtgta aagtagttgt ttaattggtt caatacagaa cgagtaacac cttcgcgtgc
     1021 cgcaccaaaa ccaacgtttg cttctacttt accagttccg gcattacttg tcataatgat
     1081 gatcgtatct ttaaagctga ccgttcttcc ttgtgcatct gtcaatcgac catcatctaa
     1141 gatttgcaag aacatatgca aaacatctgg atgagctttt tctacttcat ctaacaagac
     1201 aagactgtaa ggatttctcc gtactttttc tgttaattga ccagcttctt cgtatccgac
     1261 ataacctgga ggagaaccaa tcaatttaga gacactatgt ttttccatat attcagacat
     1321 atcgaaacga atcattgaat cttgtgaacc gaatagttcg taggcaagtt gtttcgcaag
     1381 ctctgtttta cctacaccag ttggtccaac aaataagaag gagccgattg gacgattctg
     1441 tttgtttaat ccaacacggt ttcggcgaat cgctttcgct actcgatcta cagcgttatc
     1501 ttgtccgatg acatgagctt tcaagtcatc tgctaagttt ttcagttgtg tctgttcttt
     1561 ttcttttaat tcacccactg gaatacctgt ccgttgttca acgatttttt ccatatcttt
     1621 ttcggtaatc acaggtgttt cctcttcagt gagctgacgt tctttcattt tttgaagttt
     1681 attgatctga tcgcgataat aagctgcttt ttcgaaatct tcttctcgag aagctaaaac
     1741 tttttgttct tctgcttttt gcagtttttt ctcgattgtt ttaggatcaa cgatttggat
     1801 cgtcaagttt ttcttagaac ctgtttcatc tagcaaatcg atggctttat ccggcaagaa
     1861 gcgatcttgg acgtaacgat tggataaagt tgcggctgct tcgatggcct catcagtata
     1921 ttttacatga tgatagtctt cataacgttt ttgcaaacct ttcaaaatac tgatcgtttc
     1981 ttcgacagtt ggttcatcta cccgtacagg ttgcatacga cgttctaaag cagcgtcttt
     2041 ttcgatgatg cggtactcat ttaaggtagt agcaccaacc atttgcaatt ctcctcgagc
     2101 taaagctggt tttaaaatat taccagcatc catatttcca tcaccagcag aaccagcacc
     2161 gactatttcg tgaacttcat ctatgaatag gatcacattt tctgcttgac ggatctcttc
     2221 aatcaatttt tgcatacgtt cttcaaattg tcctcgtata ccagtacctt ggactaaaga
     2281 tacgacatct aaacgaatga cttctttgtc cattaatttt tgcggtacat caccatctac
     2341 gattttttgt gctaaacctt caacaactgc tgttttacca acacctggtt ctccaatcaa
     2401 gacaggattg ttcttggttc ggcgatttaa aatttcaatg actcgtttga tttcgtcatc
     2461 gcgtccgatc acaggatcga tatcaccttg tcgtgcttgt tctgtgatat tgattccgta
     2521 ttctcccaat aaaccttctg tattgccttg aggtggctga ccaccattga agttgttgtt
     2581 tccgccaaat tgtgttggtg gtgtttgctc ataatttcct tgctgttgca tttggcgaga
     2641 catggaacgg aaaagatcgt ccaaactgcc aaatccaaat ggatcatttt gggccatatt
     2701 agtcagacct ccattttgtt gatttttgat tttttgataa cagctctgac agtaatcgag
     2761 ttgtgtccgc tgaccattga cagtggcata caagtgaatc gttgcctcat tcttgccgca
     2821 gttttgacaa agcatgaatc attcacgtcc tttcacaaaa atgggtacat ccatatttta
     2881 catctcgttt ttcatgaggt aaaagaataa cccctagttt tttaagagat ttatgaggta
     2941 gaaaaggtga aatctctatt gaccattcct gacctttgac tcttattata ctaaaaataa
     3001 aaagggaagc aagtaattcg tttcatatga aaacaaagag ggtcaaagga aagaatgata
     3061 aacgtcagga gaagagaaag cgacaagaaa aaggaaataa acacgtttgt tataaaatgt
     3121 gaagaaaagg atgaaaaaga atccggaata atttgaatac ttttatctga aattgaatga
     3181 aaactgttgt atctaacgaa aaaaaatgtt aatctttaca gatgaaaggg tggcatttgt
     3241 taggattctc tgaattacta aaaaagaaaa ccctcacata aaaacaacac tcacttaaag
     3301 gagaccgatt aatatggaaa agaaagaatt tcacgtagta gcagaaactg ggatccacgc
     3361 tcgtccagct acactattag tacaaacagc aagcaaattt aactctgatg taaacttaga
     3421 gtataaaggt aaatcagtaa acttgaaatc aatcatgggc gttatgtctt taggtgtagg
     3481 tcaaggttct gatgttacta ttactgcaga aggtgctgac gaagctgatg caatggcagc
     3541 aatcgttgaa acaatgaaga aagaaggctt atctgaataa tggttgaaat gctaaaaggg
     3601 attgccgcta gtgacggtgt agccgttgca aaagcttacc tgctagttca accggattta
     3661 acattcagta aggcaacagt agaagatact gcggctgaag aagctcgttt ggatgctgca
     3721 ttagctaaat ctactgaaga attgcagcaa attcgtgaaa aagcagcgca aagcttaggt
     3781 gaagcagaag cgcaagtatt tgatgcccat ttgatggttc tttcagatcc agaaatggta
     3841 ggtcaaatca agcaaaatat taaagacaac agcgtaaatg ctgaatcagc gctaaaagaa
     3901 gtaacggata tgtatatcgg tatgttcgaa gcaatggaag ataatgctta tatgcaagag
     3961 cgtgctgcag atattcgtga cgttgctaaa cgtattttag cgcacttatt aggcgttact
     4021 ttaccaaatc catcaatgat caacgaagaa gtggtcgttg ttgcacatga cttgactcca
     4081 agtgatacag cacaattaga tcgcaatttt gtaaaagcgt ttgtaacaga cattggtgga
     4141 cgtacttcac attctgctat catggcacgt tctttagaaa ttccagcaat cgttgggaca
     4201 aaagaaatta ctgctaaagt caaagaaggc gatattttgg ctgtcaacgg gatcgaaggc
     4261 gatgtaatca tcgatcctac agatgaacaa aaagctgaat ttgaaaaagc aggtgcagat
     4321 tacgcagcac aaaaagcaga atgggaaaaa ttaaaaaatg cagaaactgt cacagctgac
     4381 ggcaagcatt ttgaattagc tgcaaacatc ggaacaccaa aagatctagt tggtgtccat
     4441 aataatggtg gagaagcagt tggtctgtac cgtactgaat tcctgtatat ggattctcca
     4501 gacttcccaa cagaagatga ccaatatgaa gcttacaaag ctgtattaga aggtatggaa
     4561 ggaaaacctg tagttgttcg tacaatggac atcggtggag ataaagaact accatatctg
     4621 caattacctc atgaaatgaa tccattctta ggatatcgtg cattgcgtat cagtttatct
     4681 gaacaaggcg acgaaatgtt ccgtacacaa atgcgtgcat tgcttcgtgc atctgttcat
     4741 ggtaatttac gtatcatgtt ccctatggta gctacactca aagaattccg cgcagcaaaa
     4801 gcgatctttg aagaagaaaa acaaaaattg ataagtgaag gcaaggaagt atctgatacg
     4861 atccaagtcg gcatcatgat cgagattcca gcagcagcag tcttagcaga caagtttgca
     4921 aaagaagtag atttcttctc tgtaggtacg aacgatttga ttcaatacac aatggcagca
     4981 gaccgtatga acgaacgcgt ttcttacttg taccaaccat ataacccatc aattttacgt
     5041 ttgatcaaaa atgtaattga tgcagcacac gctgaaggaa aatgggcagg tatgtgtgga
     5101 gaaatggctg gagatcaaac agctgttcca ttgctagtag gtatgggtct agatgagttc
     5161 tcaatgagtg cgacatctat tcttaaaacg cgtagtttaa tgaaacgctt ggacacagcg
     5221 aaaatggctg aacttgctga tcgtgcattg aaagaatgcg atacgatgga agaagtcgtt
     5281 gaacttgttc atgaatatgt aaaataaaca acgtatcaaa agctggtgtg gcttgtaaaa
     5341 gag
//
LOCUS       DARPZF010000100         5318 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.106, whole genome shotgun sequence.
ACCESSION   DARPZF010000100 DARPZF010000000
VERSION     DARPZF010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.106"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(178..681)
                     /locus_tag="SLE65_002726"
     CDS             complement(178..681)
                     /locus_tag="SLE65_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEI8449960.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(804..1568)
                     /locus_tag="SLE65_002727"
     CDS             complement(804..1568)
                     /locus_tag="SLE65_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEI8449961.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            1676..1951
                     /locus_tag="SLE65_002728"
     CDS             1676..1951
                     /locus_tag="SLE65_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEI8449962.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            complement(2152..2499)
                     /locus_tag="SLE65_002729"
     CDS             complement(2152..2499)
                     /locus_tag="SLE65_002729"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449963.1"
                     /translation="MIPSVSFLFKKLKTFFILPEIEESNELTASDRSAFLLPVFNTWG
                     KAPQKQPYRRCSKVSFLVLRQIYAKMWKAIFTKFSLILKTKRLFHNQSLMLDADQLFH
                     NLIDGVLSAASRY"
     gene            2667..3596
                     /gene="yidC"
                     /locus_tag="SLE65_002730"
     CDS             2667..3596
                     /gene="yidC"
                     /locus_tag="SLE65_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEI8449964.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQPKNSTNNKGRNAGKQQKRK"
     gene            3699..5047
                     /locus_tag="SLE65_002731"
                     /pseudo
     CDS             3699..5047
                     /locus_tag="SLE65_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012008915.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            5145..>5318
                     /locus_tag="SLE65_002732"
     CDS             5145..>5318
                     /locus_tag="SLE65_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HEI8449965.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDK
                     LKQRDTVIIACVIW"
BASE COUNT         1705 a         1009 c          989 g         1615 t
ORIGIN      
        1 caaaagtcgt gtcaaagtcc cttgtttcga atgaatggtg ttcaaaagct tgcatctgca
       61 gtaataagcc gaaacttcac aaaaatttga gaagtaattt tcgtaaattc cttcttattt
      121 cttgaagctg accacttctg tcacaacctc aatatggtct attattggtt ttacctgtta
      181 aatcgaggat tctttcccaa agtaacgttg ccatctctta cgcatacttg cagacatggg
      241 ctgagccgct tctttgactg cgcagtattt gtccacgaat gtcacaatat atccttcttt
      301 atacttaggc ggtgcgatcg ttgcacccca catgtgcttc aaaatgatat ctcgctcaag
      361 atccgacaaa tcggtgattt tttctgcatt ctttacagca attcttggat ggatatacgc
      421 atgtgtcccc tcgtcaaatt tcgtcgtacg ccaatcatag tagaacagat catgcaaaag
      481 tccagcacgc gctgttgctt tagcattgcc accccatttt tttgcgagca gataactata
      541 gtaagaaaca ctgatggaat gctccaaacg agtggaatga acatgctgtg tgtaattcgc
      601 taattttttc actgcttctg tttctaaaag atcttgtaca taagacatat attcttcgtc
      661 ttcacgccat ttttctgtca taattatcga tctgccacct ttttgaattt cattttcttc
      721 tgaaattgat ctaagtatac caccagtgtt cggattattc tagtcgctct agataaaata
      781 gctaaagctt aatagttcct taatcataaa gaaaaatgat aaagaacgat ccctgctgcg
      841 actccgacat tcaatgattc cgcatttcct ttcattggga tatatacgtt ctgatcagtc
      901 aaagacaaga tttcctgact gactccctga ccttcgtttc ccatgattat agcgaaatcc
      961 tctgtttttt ctactttgtc taatgcatgt gcttcttcat ttaattctgt accgtacacc
     1021 gtaaaccctt tgcctttcat tacagggatt acatctgcca aatctttttg taacacaggc
     1081 aaatgataat tgcttccctg catgcttcgc agcacctttg tactataaat atctgccgtt
     1141 cctttaccta ataaaacacc agccatacca aacgcatctg ccgtacggat catcgttccc
     1201 acatttccag gatcctgtac attatctagt aaaagccagc ctcctgaaaa atctggcgta
     1261 tcttcagatg ttaacgtcat cactgctaag atcccttgcg gtgtaggtag atctgacata
     1321 gcggtcatga cctcatctga aactagaaaa gtagaaatct ctttgtttac agccagccag
     1381 tctccccatt ctttcatacc tctctgtgtc acaaaaagtt cttttatttc tgcatcagac
     1441 gacgcagctt cttcgatcag atggaaccct tccaaaagat attctgcctt ttcttctctg
     1501 tatttctttt tatgtagttt ttttaattct ttgattcttg gattttttgc tgattggatc
     1561 tctttcacat tccttcacct cacctgatta tatcatggaa taggtgcttg agcttgtttc
     1621 atcctaaaaa aatcggtatc attgatttat aaaacaggaa agaaaggtga cgaacatgcg
     1681 caaagttaaa atgaatgtcc aaggacgtgt ccagggcgtg ggatttcgct atatgaccaa
     1741 gatggttgct gatcagttag gcgtgaccgg aacggtaaaa aacgaagacg acggctcagt
     1801 cacaatcgaa gcaatcggaa atgacgacat catccaaaaa tttatcgaag aagtcaagaa
     1861 gtctccgagc ccaagtggac gagtgcagta tgtggatgtc caagaagatc cgatgattga
     1921 ggaacgaaag aaatttgatg tggtgggata aggttgtgaa aaggtcgctt agttttgagt
     1981 attaaggaaa attttgtgaa aatggctttc cacatttttg cataaatttg acttaatacc
     2041 gagaaactga cttttgaaca ccgtcgataa ggttgttttt gaagcgcttt gcctcgagta
     2101 ttaaggagaa acattttcaa aatagcttct catattttga aatgtaatga cttaataccg
     2161 agaggcagct gataaaacac cgtcaataag gttgtgaaaa agctggtctg catcaagcat
     2221 taaggactgg ttgtgaaaaa gtcgcttagt tttgagtatt aaggaaaatt ttgtgaaaat
     2281 ggctttccac atttttgcat aaatttgtct taataccaag aaactgactt ttgaacaccg
     2341 tcgataaggt tgtttttgag gcgctttgcc ccaagtatta aagacaggta gtaaaaaagc
     2401 tgatctatca cttgcagtga gttcatttga ctcctctatt tcgggcagaa taaaaaaagt
     2461 ttttagtttt ttaaataaga aagaaacact tggaatcact cttttctttc caagtatttc
     2521 tttcttgatt ttttgtcttt tttcaaaatt tttcgctacg aaaaagaaag aatatttata
     2581 tgaaatttct atgaagttga ttgaattcca tgcgcttttt tagtatagtt aagtttgtgt
     2641 aaaaattata gaagaggaag tattctatga ataaatggaa aaactggtta ttgggatccg
     2701 gacttgtcag tatcctgctc tttttatctg gctgtgtgcg gatggattca aacggaaacc
     2761 ctgacacttc aggaatcgtt tatcgagtac tcgtccatcc tatgggccaa gcgattacat
     2821 atctagttga gaatttcaat tggtcttacg gctgggcagt tattgcaatg actgtgatcg
     2881 tccgtatcat catcttgcca ctaggtatca gtcaatcaaa aaaaacaatg atccaatctg
     2941 aaaaaatgca agcgttaaaa ccacaagttg aagcagcaca acaaaaacta aaagctgcaa
     3001 caacacgtga agaacaaatg gcagcacaag cagaaatgca acaagtatat cgcgaaaacg
     3061 gattgagtat gaccggcgga atcggctgtc tgcctctatt gatccaaatg ccgatcttct
     3121 ctgccttgta ttttacggct cgctacacag aaggtatccg tgaatcatct ttttacggca
     3181 tcgatctagg ctcaccaagt atggtgcttg ttgccattgc aggggtcgct tatctgcttc
     3241 aaggatatat ttcaacaatc ggtattcctg aagaacagaa aaagacgatg cgtacgatgc
     3301 tgatcgtctc tcctgctatg atcgttttca tgtcgatcag tgcgccagcc ggtgttacac
     3361 tttactgggt agtgggtggt gtgttcagtt gtctgcaaac attcatcaca aacgttatga
     3421 tgaaaccacg tttgaaagca caagtggcag aagagttgaa acaaaatccg ccaaaacaag
     3481 tcgtcactcc aagaaaagac gtgacagaat cggcaaagcc agctgacaat aaacaaccaa
     3541 aaaacagtac aaacaacaaa ggccgcaacg caggaaagca gcaaaagcgg aaataaaaat
     3601 atatgacaaa aaactgtaga caaataaaaa aatttctttg ttctacagtt tttttgttac
     3661 aatcaaagaa aacgtcgctt ttcgaggagg aatgtataat gatgtccaaa taatcaatgg
     3721 atagtcgaat ggaagaagcc aaaatttcgc tagatgcact tgttcctaaa aatcatttgg
     3781 tccataaaat tgacaaaata ttgttatttg attttattta tccaattgtt gaatcaactt
     3841 actcgaccat tggtcgtcct agcgttgatc ctgtcatctt agtaaaatta gtattcattc
     3901 aatatttatt taggattcgt tcgatgcgtc agtccattaa agaagctgaa acaaacctag
     3961 cttatcgttg gtttcttggg cttagtttaa tcgataaaat tcctcatttt tcaacgtttg
     4021 gtaaaaacta tgtacggcat ttcagagaaa ccgattgttt gaacagatat ttatcattat
     4081 ccttgaacaa gcagttgaag ctagatttat tcatgaagaa attttgtata tggattcaac
     4141 ctatattaaa gcgaatgcga aaaaacatat ttttacaaga gaaatggtac ataaataagc
     4201 cattttatac caaaaacaat tgaaagaaaa aattaatgaa gcaagaattg cagaaggcaa
     4261 acgtcctttt ggttcaatca ttcatcagga ggtggtagaa gggaaaatta gtgtcgcaga
     4321 tccagaaagt ggttattatg taaaaacaga acaagaaaaa cagtttgctt attctgctca
     4381 taccgtttgt gatgaaaatg gttttgtatt agatgtcatg attacgcctg gaaatctaca
     4441 tgacagccga atgctcgtgc cacaaatcga acgtgttaaa tcatgttgtg gtgtagctgc
     4501 tgatgctgcg tacaaaacac cttggaacgc caagtattta atcgatcgaa aactacgacc
     4561 catttttcct tatactcgac ccaaaagaag caaagaacgt tttaaaaaga aagattttta
     4621 ttatgatccc tattataact ggtacctatg cccaaatgat caaacacttc agtttcgcac
     4681 aactactcga gatggttata aaaaatatgt atctaaatct tttatttgtg aaagttgtct
     4741 attattgaaa aattatacag aaagccagaa acaccagaaa gaaatacatc gacatattta
     4801 ggaagactac ttagatgaag cagaacattt acgccatacg gtgtacaatc gcgaaaaata
     4861 taaaaaaaag aaaagaaacg attgaacgcg tttttacaga cgcaaaggaa aagcatggaa
     4921 tgcgctacac caaatatcga ggcttggaaa aaaccaggtg catacgatgc ttgtttttgc
     4981 cgcaatgaat ctgcaaaaat tagccatttg gcagtggggg catatgtctt tatacccgtg
     5041 gtgctagtta attttttcct agaggaaaat gtctaaacat gttggtaaat caacaaaaaa
     5101 acgcatatag tagtctcaaa actcccaaga aatgaggact acatatgcgt tcatcaaaat
     5161 atactgaaca ttatacagat acttttataa cattcaagga aattatgaga actgtttcta
     5221 acatatacca caattgtgta ccagataaga ttaaaaaccg aagaaatact gataaactga
     5281 agcaacgcga tacagtgatt attgcttgtg ttatatgg
//
LOCUS       DARPZF010000101         4791 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.107, whole genome shotgun sequence.
ACCESSION   DARPZF010000101 DARPZF010000000
VERSION     DARPZF010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.107"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(75..1073)
                     /locus_tag="SLE65_002733"
     CDS             complement(75..1073)
                     /locus_tag="SLE65_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HEI8449966.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1148..1444)
                     /locus_tag="SLE65_002734"
     CDS             complement(1148..1444)
                     /locus_tag="SLE65_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HEI8449967.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1437..1730)
                     /locus_tag="SLE65_002735"
     CDS             complement(1437..1730)
                     /locus_tag="SLE65_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449968.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1876..2427)
                     /locus_tag="SLE65_002736"
     CDS             complement(1876..2427)
                     /locus_tag="SLE65_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HEI8449969.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2601..2900)
                     /locus_tag="SLE65_002737"
     CDS             complement(2601..2900)
                     /locus_tag="SLE65_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HEI8449970.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEIGTLPKDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            complement(2927..3235)
                     /locus_tag="SLE65_002738"
     CDS             complement(2927..3235)
                     /locus_tag="SLE65_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEI8449971.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQLPLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEERKEYLISPKLRLKSVSQKIWAIDSGEYQTMLLPEEY
                     "
     gene            3540..4223
                     /locus_tag="SLE65_002739"
     CDS             3540..4223
                     /locus_tag="SLE65_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449972.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIE
                     IGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSE
                     ALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLY
                     DNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKANGVTELAIYQKG
                     KRIMVPLPV"
     gene            complement(4260..4757)
                     /locus_tag="SLE65_002740"
     CDS             complement(4260..4757)
                     /locus_tag="SLE65_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8449973.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT         1424 a          908 c          700 g         1759 t
ORIGIN      
        1 taaaaaaact gattctaaga aaattaaata atttttctca aaatcagttt ttctttgata
       61 aataatattt tcaattattt aatcatttga aaattgttag tcattccaat acgttgagaa
      121 attcttccat ctgtataaac acgaaattgt tttccaccag ccatggtcgt gtttccatca
      181 tcatccgtta caatattaat tgaatagtag cttccatttt catcttgcat tagatctttc
      241 atatattcat ttgtgctaat taaattagta tttgatacat ttttatcagg agaatcatac
      301 aaccataaag ctttattatt tagcacagat tctttagcag cttcccaact tgaaattcct
      361 gaactacttg tagattgtgt cgttgtagtt gttgcttgtt gagtagattc ttctactact
      421 ggtgtttgag gagtttgtcc attcacaata tcactgaaac cttgttttaa ctgttgattt
      481 tgagtttcgt taaagtacag ataattattt tcattacctt gattttgttg cgttaaataa
      541 actttaggtt gtccattttg aaaaccgaaa aagtaaacat gctgccctaa atattctcca
      601 gtttctacat cagaataaac tgctactaaa ttgaaatctg catgaccagt tccatcttct
      661 gaccattgta cggtaactgg tgcttcattg attgccattt tccaatcgcc attaatcacg
      721 gcttgtggta aaggagtgcc atacagactt acattattct gaagattgta gcttttatat
      781 tcttgaccta atgtctttcc ccattgtgtg acaaaagttt ctaatttgga agctttattc
      841 gtatcccaca aagtattctt aacctcttca gaagaagatt cagtgattga acttgcactt
      901 gtttccacag attgcttcat ttctgttgta gtttgttcag ttgattgcgt tttacttttt
      961 ttagtctcaa ttgttgtatc agtttctata gtcgctttag tcctcgtatt ctcagatgta
     1021 caaccagtga ataaaattcc cattcctatt agtaataaca gccatttttt cattatattt
     1081 ccccctttca atttctccct cacgtactta ttctatcaga caattaattg atctaaatgg
     1141 taatctttta atcgattctt tcccaataat gtcgatagcc cgtatggcag cggtctcttc
     1201 cttgaggact ctcagatgga ttaaaactag tagaaatttc ccttccacat cctctacagc
     1261 gataagttct cattattttt gggctattag tattattttt cttagttaga gctatgagtc
     1321 caactatgat taccccaact gtcttaatta cttttccttt atctatattc ggatgcgcaa
     1381 gcatatattt atataaccaa tatccaccgt aaattaaacc acctaataca atcagcttag
     1441 ccatgtactc gtctcctttc tttttgttta attacttttt gaatccatct tgcagagaaa
     1501 ccataaactt ctgtcaattg acggatatct acagtttttt cctgttctat catgttttcg
     1561 attctttttc taactaactc acgatcgtac attttcattg gaaaagaaat ctgttgccct
     1621 cgaaaagcaa gataaaattg atagagcaat tctgaatcca gttccatttc ctcaaaaaag
     1681 tcattcatac ttttataaga gttactcaaa caagtttcat caatctccat ctacacaccc
     1741 cctgttattt tttacataat gaaaatagca tattactggg tacattgata attcatataa
     1801 catgtatcat cacatgtatt tttaaagtca aaaagcatgt aaaactactt ataagtaaca
     1861 tgagaaaata aaatgttatt tttcttgaaa taataattga ctatctgcca attgccattc
     1921 attacgaaca tgaatactta gtgggtggga taacttacct tctgcattta tcaatacttt
     1981 ggtcatcttc ttttgtttcg cactcaattg atcgtaaata gtctttgctt gttcataagc
     2041 cacttgactc gtcgctgtaa tcgaaccaca agcaaaaata atggtattga ttttcttttc
     2101 tgtaaaaaca gtcgttaata tttccaaaga ttgttcatca tttcctcgaa gaaatacccg
     2161 aggacttttc gcttttgtgt acgaaaaaag attcacagca ataaaaccag taaatcctaa
     2221 ttgtcggata ttcttttcga ttaataacat actcaaatca ttcgtaaatg gttctgtatc
     2281 tgttggacga atagtaatga ctactgctaa tttatcttcc gcttcttttc ctttgatcgc
     2341 ccattgtcgt ttgaaaacat agcgatgggt atgatgagga tctcgccaaa cttctgtttg
     2401 tgtggtcact aattcttttt caatcatctc tttttctcct atgctatttt ttgttcaagc
     2461 acttcaatta ccattgccgt tataagtgtc aatactagtt gaaaatattt catattcttt
     2521 ctcctttttt cttcagaatt tgatgaatcg cggtaaggat atcttctaaa catttcgcaa
     2581 tcattctcaa ataatcgatc ttattcatcc gttcctccaa tctgactcca aaccaatcgt
     2641 ccttctacca gtaacccacg aacaaattct cgctggctgg taatatctgt aatgaaataa
     2701 actacatagt cttttccatc ttctggtgcg caataaatat aaagatgtgt catcactaaa
     2761 cgtggtagat gaacatcttt aggaagtgta cctatttcaa tttcctcttt ttccatcgta
     2821 acggattcat agccccactc ttcagaagca gtgaccagct gtgcacactt ttccagtact
     2881 tcgatagccg tttctaacaa gtcctttcgt tcctttcttt tagatactag tattcttctg
     2941 gtaataacat cgtttgatac tcacccgaat caatggccca tattttttga gacactgatt
     3001 tcaaacgaag cttaggtgaa atcagatact cttttctttc ttccggttct tcttgacgat
     3061 gaaccaactt ttgatttcct ttttccgtag aaaattcaaa aatttgaaga tagtctaaag
     3121 gaagttgctt ttgaacgttt tgatcgatta gattccaaca taaagcttgt aattccaccg
     3181 gcaaactgtc cattactccc tttgtgacat aacgttgtcc tttattttga aacatttctt
     3241 ttccctcctt tgctataaaa atagcccaat cttctattaa agaagattgg gcttcatgga
     3301 tataatatat atttgtaaat aaagttaatt cagttataat tatcaaaact acacaattat
     3361 taaagttttt catatctctt tgtttagtaa gtttttctaa atcttaaccc gtggtgctag
     3421 ttaatttttt cctagaggaa aatgtctaaa catgttggta aatcaacaaa aaaacgcata
     3481 tagtagtctc aaaactccca agaaatgagg actatttaac aaactacgat ggttacgtcg
     3541 tgacaactga acattttgac ttagccaatc ctgttactaa agtcgatgat atccccgatt
     3601 atgaaatgta cagtcaaaca atcgatagct taaataagcg ttttggcaat cgtgttttaa
     3661 aaggcatcga aatcggttac atcgcttctg aaaaggatcg gatcatcgac tatttagccg
     3721 ataaagatta cgatttaaaa ttactcagtg tgcatcataa tgggcaattt gattatttag
     3781 atgacgaagt caaagatatg gatcctgcta ttgtgattcc tcagtatttt gcacaacttt
     3841 cagaagcact agttgttata gaagcagatg tctttgctca ttttgactat ggttttcggg
     3901 tatttggtct atccgttgct gaatttaaac aatatgaagc gcagttttta ccgattctag
     3961 atcaagtaat caaaaataaa ttggcattcg aattaaatgc taagagcgct tacttgtatg
     4021 acaatttagc gttatatgaa tatgtcatcg atttatatct ttcacgtggt ggtaccttgt
     4081 ttagtgttgg atcagatggg cattaccttg aacatttccg tttccatttc gatgatcttt
     4141 ttgctctgtt aaaagcaaat ggtgtgacgg aattagcgat ttatcaaaaa ggaaagcgaa
     4201 ttatggttcc attaccagtc taaaaaaacg tcctcagcat caaaagtgag gacgtttttt
     4261 tagatttctt tttctaaaat cggacaaata cgatcttgtt ttcctaaagg aaaatgtttg
     4321 atcccgattt ttttaaatcc atgacgttca taaaaacgaa tacctgcatg atttttttca
     4381 taaacagtca aacgtaaata acgtttttgt ttcgttttag cataacgatt cgcttcatcg
     4441 agtaaccgtt gccctaaccc tttgttttga taatctttga gcagatagag ccgttgaatc
     4501 tctatagcat ctttttcatc attgactttc atataaccaa tgagtatttg atgatcctta
     4561 ataccaataa atttactggt tgactgtgcc aattctactg ccaatatttc agttgtcaat
     4621 tgtgtctgta aatatccttg catatcaagt ggatctgcgc catcgataaa cgattcataa
     4681 aaactgacaa cacttacaac ttgtaaagca tctagatcat cataatctaa atacgctagt
     4741 gtgatttgat tgttcatcta actcctcctt ttgacatagt atactataaa t
//
LOCUS       DARPZF010000102         4662 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.108, whole genome shotgun sequence.
ACCESSION   DARPZF010000102 DARPZF010000000
VERSION     DARPZF010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.108"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(172..474)
                     /locus_tag="SLE65_002741"
     CDS             complement(172..474)
                     /locus_tag="SLE65_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449974.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(694..1060)
                     /gene="ssrA"
                     /locus_tag="SLE65_002742"
     tmRNA           complement(694..1060)
                     /gene="ssrA"
                     /locus_tag="SLE65_002742"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1231..2004)
                     /locus_tag="SLE65_002743"
     CDS             complement(1231..2004)
                     /locus_tag="SLE65_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEI8449975.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTYYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2148..2498
                     /locus_tag="SLE65_002744"
     CDS             2148..2498
                     /locus_tag="SLE65_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HEI8449976.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2479..3195
                     /locus_tag="SLE65_002745"
     CDS             2479..3195
                     /locus_tag="SLE65_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8449977.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3195..4643
                     /locus_tag="SLE65_002746"
     CDS             3195..4643
                     /locus_tag="SLE65_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEI8449978.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
BASE COUNT         1549 a          822 c          900 g         1391 t
ORIGIN      
        1 ttataattgg agtggtagtt aattagtgac ttatttttga ttttatagca ctgatactat
       61 aaaatataga tatcatcata ttacacaatc ttaatactaa cttaaaaaat atccctttta
      121 taagtatggt gataaaatcc gttccgggct acctttttta ggtagcctac tttaatcttt
      181 atacctttct ggatcaacga aagtatactt caaatagtca taacgccgat gatcgctccg
      241 tgcgtctggc acatcagtca cgatatcaaa caaaaaatac acatctttct tcattctggt
      301 ttttgttgcc ggaattttaa agtagttctt attagagtaa tagagattga ttaataagct
      361 atcttcgatt gctaaaaaga aaacttctga atcccacacc ttataaaaat ctttgacaaa
      421 tctattcgaa ggatcaaatt taaaccataa ttgtgttttt ccttccatca acataatgtt
      481 cacctcaaaa agagtatacg aactaatgtt ctttttgtaa agtaggaata tcattgataa
      541 tatggatgga acatatatat taaaaagtgt tctttttgaa tgctattttg aatgccattt
      601 tcattcattt aacgaaaatc tgcgaaaata aaaaatgctc aaacccttat aaaataagga
      661 tttaagcatc tagcgaaatc tgctgaaatc tcacaatgga gacggcggga gtcgaacccg
      721 cgtccaaaca catcgccact taaaaatcta cgttcatagt caactcattt aaggattcac
      781 tttacagctt gccgagtgac aggcattctg tatcgctagt ctgatgttct ctttttcaac
      841 ttacagacgg aaagttgaaa cgtatcccac taaagttagg acccttactc gagcacatgg
      901 gcgatgccga gaggatctac gctaactgtt tttaggcagc taaagcgtaa gagttgtttt
      961 cgtttttagc agttatattt aactgtaacg tttttacgta gacgtaacct acgaaacgca
     1021 attcaagctc gactgtgcct gtcgaatccg taacgtcccc gttagctaac aagggttacg
     1081 tgtatttttc atacaaaatt agtatagcat atattgggat aaattcaata aaaaagcgaa
     1141 tcatatccca ttatttatat aataactgcc cctttcttaa gaaaaaataa gcgattttct
     1201 taagaaaaga ggtagcttca aaaaaagatc ttaaatcaga tcaaaatact tcaatgcgtg
     1261 gacaattccg ccttctgtat ttttctttgt gataaaggta gaaagttctt ttaatccgtc
     1321 ataggcgttg cccatagcga ttttgttgtc gcaagcttcc aacaaggcaa aatcattcgg
     1381 accatcgcca aatccaaaag taggaacttt ttccagctga agttcttttt gcagacgttt
     1441 gacacctgcc ccttttgaga ttcctttctt cactgtatcg atcgagtaag gaccattccg
     1501 ataataagtt agctcaggaa aatgttcgtg atagtattcg tcacctgatt gagataagat
     1561 cagcaacata tttactgtgt tttctttaaa gcctaaagga tcaatttccg gaacatctga
     1621 atgaatgaag tcgtaagcat tgatcattgt ttggctatga ccggtacacc agattttctg
     1681 atcgttatag taagaaagtt catgaccgtt caactgtaca tgatcataca ttttttgaca
     1741 ttcttctgaa gaaaatgttt gagaatagat ttcttcgccg tctactcgaa tgaaagaacc
     1801 attcatggtg accgcagaag taatgcccgc atcttccatg atagagtgga tttctgcttc
     1861 tgtacgtcct gtagcgatga cggggagaac attgttttct tttaatgcgt tcatagcttt
     1921 tgccacttcg ggtgtgattt ttgatttcgc atctagtaat gttccatcaa gatcaaagaa
     1981 agtgattgca cgataatttg acacaaataa aactcctttt ttattggaat aagtttatct
     2041 taacaaagaa tgaacaaaag acaaaccttt cgtgaagaat tcctgaacat attggttcag
     2101 tcaacaattt agagtatact ataagaagag aatttaggag ggaaagaatg atttttttca
     2161 gtattggtat cttattctta ataattggca gtctttttcg gattctgccc tcaaaaggaa
     2221 atctgccttt ttatgggtat cattcgcctc ttgccgcaaa aacagacgct cattggcggc
     2281 tggctcaaaa gacaagcgga aactggtttt ttcttatggg cttactgatg gcattgatcg
     2341 gctattattt aaagacatct gggcatacga attattttct gattgaaatg cttctgctag
     2401 tatttccaat tatgcctatt tttattatga cagaaaagaa attacagaaa tatgacctgg
     2461 aaactggagg gaacgataat gaatatttta atgattgaag ataatcaatc tgtttctgaa
     2521 atgatgcaga tgtttttctt aaatgaaggt tgggaagcaa ctttcaagta tgatggaaaa
     2581 gaagggctcg atgccttttt agaaaaccca caacattggg atatgattac actagacctg
     2641 aatttgccca cactggacgg tatgctagta ggaagagaga tccgcaaagt ttcaagtact
     2701 gtgccgatta tcatgctgac agctagagat tctgaaagcg atcaggtgat cggcttagag
     2761 atgggggcag atgattatgt cacaaaacct ttcagtcctc tgacgcttat tgctcgaatg
     2821 aaagctttgc atcgccgtag tgagttggca gaagcaagag aagaagcagt agtttcagat
     2881 gatcattttg atatcgagac tagtcatttc aagatgaata cgaaaacacg agaagcgtat
     2941 ctggacaacc ggccaattga aggactgacg cctaaagagt tcgatctatt gtttacttta
     3001 gcaaaaaaac cacgtcaagt attctctcgg gagcagttgc ttgaattagt ctgggattat
     3061 cagtactttg gtgatgaacg gacagtggac gcccatatca agaaattacg acaaaaaatc
     3121 gaaaaggtcg gaccacaagt catccaaact gtttggggag tcggctacaa attcgatgat
     3181 tctggtgttg cctaatgcgt tatttgtatc agcaactctt agctttctgc ggaatggtcg
     3241 cgttgatctt attgatcgtt ggagtttctt ttacacaact gacaaaacaa acgattgaag
     3301 aaaacaatta ccagcaactg tttggatatg ctgaatcagt tgaaaagaca acgcaaacct
     3361 atgccgatac gctcccgcag tttagtcaag atcaggcgtt tcaaaatgca ttgctgctga
     3421 cagagcaagt actgacagaa caaaatgtga actttatatt tatcgataaa aacgaacgtg
     3481 tcatttatcc gactaataca gctttactga attttacctt aacagctgat caatggaaaa
     3541 atctgaggaa tggacgtcaa gaaaaattca catcgaataa aaatatttta ggacaagcac
     3601 aggcgacctc ttacgcactt gtgccattta atttgaatca tgaattctat ggagcacttg
     3661 tagttagtca acctgcgcga aatatcgata acagcgttcg tccaattaca ctgaacctgt
     3721 tcaaaggatt tattttttcc agtatcgttg cagttattgc cagctatgct tttgcagcat
     3781 tccaagttaa gcgtatcaat cggttaagga atgcgacgaa agaagtgacg aatggtaatt
     3841 ttgatgtaca gctccccgta catgacaaag atgaatttga tgagttagca gatgatttca
     3901 ataaaatgac gaattcattg aaagaatctc aagcagaaat tgaagaacaa gaaaatcgtc
     3961 gaagacaatt tatggcagat gcttctcacg agatgagaac acctcttacg acaatcaacg
     4021 gacttctgga agggttagaa tacaatgcaa tccctgaaaa tcagcgagaa aacgcgatta
     4081 aattgatgaa aaatgaaaca gagcgtctga tccgtttggt gaatgaaaac ttggattatg
     4141 aaaaaatccg tacgaatcaa atcagtatgg tcattaaaaa attcaatgga acagaaacat
     4201 tgaaaaatat tgttgcacag ttagaagcta aagcagaagc agcaggagat acattgacat
     4261 tgaaagccgt tgatgatatt gatgtttacg ctgattatga ccgatttgtc caaatcatgg
     4321 tcaatattat tcaaaacgcg atacagttta ctgaaaacgg ccaaatcacg attactttag
     4381 aaaaaggcta tcttgaaacg atcatcacga ttgaagatac gggaattgga atgtctgaac
     4441 aacaaatgaa aagtatctgg gatcgttatt ataaagtaga tccttcaaga aaaaatacaa
     4501 aatatggtga atcaggatta ggtttaccaa tcgtgcagca acttgtacgc ttgcataaag
     4561 gaaaattaga agtagaaagc gaactaggaa aaggaacaaa attcgctgtt cgtttgcctg
     4621 acgtagaaat caaaaaagag taaaaaacaa gcggtataaa ag
//
LOCUS       DARPZF010000103         4617 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.109, whole genome shotgun sequence.
ACCESSION   DARPZF010000103 DARPZF010000000
VERSION     DARPZF010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.109"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(15..962)
                     /locus_tag="SLE65_002747"
     CDS             complement(15..962)
                     /locus_tag="SLE65_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HEI8449979.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(1140..1943)
                     /locus_tag="SLE65_002748"
     CDS             complement(1140..1943)
                     /locus_tag="SLE65_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEI8449980.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            2089..3003
                     /locus_tag="SLE65_002749"
     CDS             2089..3003
                     /locus_tag="SLE65_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEI8449981.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            3051..3521
                     /locus_tag="SLE65_002750"
     CDS             3051..3521
                     /locus_tag="SLE65_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEI8449982.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            3606..4214
                     /locus_tag="SLE65_002751"
     CDS             3606..4214
                     /locus_tag="SLE65_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEI8449983.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            4348..4548
                     /locus_tag="SLE65_002752"
     CDS             4348..4548
                     /locus_tag="SLE65_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEI8449984.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
BASE COUNT         1512 a          716 c          912 g         1477 t
ORIGIN      
        1 attgttttca gctattaata tcctgcagac aattttactt gattggtttg aagctcatgg
       61 gtggcaaagt agcttttcag attggttaaa aaaatagcca ttaatttctt ttgaaaatca
      121 ggtgtcaaac ctgcaatgtg ggaagtaatc agtacattgt ccattttcca aagaggatga
      181 tcttgtggaa gaggctcttc ctcaaaaacg tctaatgctg caaaggaaag ttgctggtta
      241 tttaaagcct gcaccagatc ttgtgtctta acagaagcac cacggccaac attgatgaat
      301 acagattttg gatcaaagtg ttcaaacata tgctgatcaa agagcccagt tgtttcctcc
      361 gttagaggta agatattgac tacgaaatct acttcaggaa gaacttcctt tagttgattt
      421 aaagaaaaag tcttttccat tccttctgct ggatgaccgg atgtattgat tccatagcag
      481 ttcatgtcta atgctttgca tttttttgca atcatttttc caatatggcc agttccaatg
      541 attagtattt ttttcccttg gatagattgg taatggaccg atgaacctaa ccatttcatg
      601 tcactctgtg ccttttgtgc ttgaaaaaga ccacgagaat acccaaggat gattcctaag
      661 acatgctccg taatcgattc actgtggatg ccactaccat ttgaaagtaa aatatgtttc
      721 tttgaaaaag tctcaagggg tagctgatca acaccagctg agatagattg gacccatttc
      781 aaggtagaag aggctaatag tttttcttgg tagtctgagt tccagcccaa actgatctct
      841 acattttgta gatcctctgg ttgtaattct gttttaaaga tataaccagg cgctatagta
      901 tggatttctt cgataaattc atcacgaaat ggacgatctg cataaatgat tctttctgac
      961 atagttaatt tcccgccttt ctttactcta agtgtagcgc atacaagaag aactttgaag
     1021 cgccttgctt gttttttgag aaagaaatat ttttcaaata aaaaaggggc tgtgacaaaa
     1081 aaatgtcaca acctctaaaa gggtctattg aagtagaaat aacgagttgt ctttatttct
     1141 taattgatcg atatttttgc ccatcctttg acagcttgag caaaaataaa gattcctgca
     1201 aaagcaatga aggcgctagt gtcaaaagaa ggaagaaaga ccatcaagat tgttgcaatt
     1261 atagtaggca atgaaattga atagatcaat gtttttaaac aatcaagaaa agtagctttt
     1321 gttagtcgaa agcgtgcata gagaaaagca gcaatgttgg taaatagcaa agtgatcagc
     1381 agattcagaa aactaggata aatagaaaat ataaatgtca ggacttttat ccaaagtggt
     1441 atagatgctt cacttaaaaa agaacggagc tgcttacctg ttaagttttt taaagattca
     1501 ttggtgtagg gaagttctaa ttggttattg ttcaacaaag cagaagtcgt gcctgtatta
     1561 ggaagagcta tgataagttt gttttttaac atcccgacac taacaaaatt ccccatcaaa
     1621 tcagtagaga tgtcctgttc tgttcgtttt ccctctggat caaatgtgaa gataatggag
     1681 tttgtttggt aaatgaatcc ttctttttct tcggtttgaa gctgcccgtt ttggattgta
     1741 aaatcaggaa tgcgagtagc aatcttttgc ccatccaatt gaatgttgtt taagacttga
     1801 aaaacttgaa aagagattgg caaagccata attatactca aaactaaaag atagacaatg
     1861 gctttccaaa atgggacatt tctcgcctcc tttaggtctt tgaatcgtat aaaggaactg
     1921 ataattaatt gttttgttgt cataagtact cctcatctag tagtgtcatc acttgcaatt
     1981 ctagcgaagt atcaagtgaa atacaagtgc tttaaggaaa cagctgaatg attggtgaaa
     2041 tatcaaaaaa atgttattct tgtctaaaga ctatccaata taaataaaat ggaggaagga
     2101 atagtgccta cacagccaca gagatcatca aaaaaactat ttggagtagt ggttttgaat
     2161 gcggtgatca ctttatcaga atttattgga gggattatgt cagggagttt gtctcttgtt
     2221 tcagatgctt tccataacct tagtgataca ttggcaatta ttttttctta cggggcacaa
     2281 aaaatggccc gaaaagaagc aaataaaaaa cgtacgtatg gctaccagcg tttagaaata
     2341 ttgagtgctt tcatcaactc attcatattg atcatattat ccttgttttt aaccgttgaa
     2401 gcattcaagc ggttcacttc accagaaaag ataaatagtc atttgatgct aacagtagca
     2461 gttattggat tgctcgcgaa tttgttctca gtattattat tacgacaaga agcagatgaa
     2521 agtttgaata taaaatctag ttatttgcat ttgttaagtg atacactgtc ttcggtaagt
     2581 gtgattatcg gagcaatttt gatccgtttt ttcgatatct actggatcga tccagttatt
     2641 acactgatca tttcgatata tatattgata gaagcgataa tggtgatcaa aaaagctgcc
     2701 gctattttga tacaaagtgc acctgctatc gactatgaaa aaatggaaca agaaattgaa
     2761 gcaatcgatg gggtaaagga tgttcatcat gtccatattt ggcagtatag cgaaaagata
     2821 attattttcg acggacatat tgattttgaa gatcagctac taagcgagat tgaaaagata
     2881 tatcctcgta taatttcttt attaaaatta aaatatggta ttacacatgt gacgatccaa
     2941 gcagagacaa aggcaaagga tcaaaaaaaa ttaatttttt taaataaaga tgaaagttat
     3001 tgaaatatag agtatgataa ataagaattt ttaataaggt aggttggctc atgaagcagt
     3061 atcgacagtt aaaaggatat ttagaagcaa aaggatattg ggagatacta gtctatctct
     3121 tttttggtgg tttggctacg attgtaaatt ttgttagttt tgctctcgca cgccaatatt
     3181 ttgatttaag tatggcctta tccaattcta tttcgtggtt ttgttctgta ttgtttgctt
     3241 ttgtaacgaa caaactttgg gtattccatt caaaatcacc gaattttaca catgcactta
     3301 ttgaatgcgg taagttcttc ttctaccgta tcctttctta cggattggac atgggggcaa
     3361 tggtattgtt gatcaatgtt atgaacagca atgagtatgt ggcgaaaatc atcactcaaa
     3421 ttattgttat ccttgcgaac tatattttca gcaagttgtt tatttttaaa gaaactgagg
     3481 tttttgaaga agaagtaggt caaagtgaaa aagacgacta ggcataacaa ttgaagaatt
     3541 tccttctctt tgttactctt tgtaatgtag acattattaa gaaaacattg aggaggaatt
     3601 tttttatgac ttacacatta ccagatctac cttatgcata tgacgcattg gaaccttata
     3661 ttgacgaaga aacgatgcat ctgcatcatg ataagcatca caatacttat gtgacgaatt
     3721 taaattcagc aattgagaaa tacccagaat taggcgaaaa aacaatagaa gaattattat
     3781 ctgatatgga cgctattcca acagatatca agacagctgt acgtaacaat ggtggcggac
     3841 atgctaacca ttcatttttc tgggaaatca tggcaccaaa tgctggtggc gaacctacag
     3901 gagaaataaa agaagcgatt aatgaagctt ttggtgattt ttcttctttt aaagaagaat
     3961 tcaaaaaagc agccgctgga cgatttggtt ctggatgggc ttggcttgta atggaaaatg
     4021 gaaaattagc tattacctct actgcaaatc aagattctcc attgatggaa ggaaagacac
     4081 caattctagg tttggacgtt tgggaacatg cttattattt gaaatataaa aatgtccgac
     4141 cagattatat tgcagcattc tggaatgtta ttaattggga tgaagtaaac aaacgtttcg
     4201 aagcagcaaa ataaccattt cctccgtcat atcagtctta aaaataattt ggaaaataaa
     4261 agagcgaaag cttgctagcg ttttctaaat tgggtataat gttcttgcaa ggttacttgc
     4321 aagaactttt ttggaggata tacatttatg gaacacggaa cggttaaatg gttcaacaat
     4381 gaaaaaggat ttgggtttat tacagtagac ggcggagatg acgtatttgt tcatttctca
     4441 gcaattcaag gagacggctt caagagccta gaagaaggtc aagaagtaga attcacgatt
     4501 gttgaaggtg cacgcggacc tcaagctgct gaagtgacta aattataata atttgttgaa
     4561 taaagacacg acttcttaga gagtcgtgtc tttttgtcta tttatgaagt ttttaga
//
LOCUS       DARPZF010000104         4539 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.111, whole genome shotgun sequence.
ACCESSION   DARPZF010000104 DARPZF010000000
VERSION     DARPZF010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4539
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.111"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(67..1746)
                     /locus_tag="SLE65_002753"
     CDS             complement(67..1746)
                     /locus_tag="SLE65_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEI8449985.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            2294..3796
                     /locus_tag="SLE65_002754"
     CDS             2294..3796
                     /locus_tag="SLE65_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8449986.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNLKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDITYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            3809..4471
                     /locus_tag="SLE65_002755"
     CDS             3809..4471
                     /locus_tag="SLE65_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8449987.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
BASE COUNT         1395 a          921 c          845 g         1378 t
ORIGIN      
        1 atttgttttt cgcaaaaaaa gagcaagacg agcactctat agagaggttc atcttactct
       61 ttttgtttat tttttatttc gacgttgagt agcttccata atgactggca agatcactgg
      121 gcggcgtttt gtttgttcaa ataagtaacg gcctaattga tctcggatgt cttgctttaa
      181 tttgctccac tcaaaatcat tgctttctaa atgtttctca acgattgttt caatcatatt
      241 gctgctttct ttcatcagat cacggctagc ttttacgtaa acgaatcccc gtgaagtaat
      301 ttgaggtttt gaaatgattt tcttttctcg ccgactgata gtgacaaccg ctacgaaaat
      361 cccgtcttct gacaagattt ttcgatcacg taaaacaatg tttccgatat cacctatgcc
      421 taatccatca atcattacat tttctgcact tgtagttcct gcaacactca tacgcttgtt
      481 cttatattcc agcacgtctc cgcgtccagt aatatagata tttttgtatg gcatccctac
      541 tgcatgagcc aaatctgcat gagcagctaa ttcacgatac tctccttgaa ctggcacaaa
      601 atatgttggt ttcatcaaat tgatcattaa ttgcaagtca ttaggattgg catggccaga
      661 aacgcgcata ttctcagaga tcaacttcac tgttccacca gctcgataaa tgatatcttc
      721 cgttttcgcc acgatggttt ccatcgcgat gcttggcgta gtagtgatat aaaccaaatc
      781 tccttcttca atcttgacat tacggtgtgt accgtttgcc attttttgca gagacttgat
      841 gggttcaccc attcggccag tttctaaaat gatcagttct tctggatcat agtttttcat
      901 gtctttcaac gtaacaagca gatcttcact tggtaattga agtttttcta aacgcatcgc
      961 tgtgcgaata attcgttcga aatcttgacc agtcaagaca acttttcgtt gtgctttttc
     1021 tgctgcatcc aatacttgtt gcactcgttg caaattactt gctacacaag cgacgatgat
     1081 acgcccttcc caatatttga tcgtatcaaa tacttcatct gctatttggg cttcagaagc
     1141 tacaggctga ggattttctg catttgccga ttcacttagt aaggctaaga ctccttcttt
     1201 gccgatttcc gccaatcgtg cataatctgt ttgatacatt gggatagccg tttggtcaaa
     1261 tttaaaatct cccgtataaa cgatactacc ttcttttgtt ttcagattga tccccactga
     1321 atctggtatc gtatgagtgg tacggaaaaa gctcactact gtttcaccaa agtctatttc
     1381 tgtatgctca tctaccacat ggaaatcctt aaatcctttg gctgcttcat tacgactgac
     1441 attcaatttt gctaactcga tcgtcaactc tgtcccgaat actggtacag aaatttttga
     1501 caacaagtaa ggaagtgccc cgatcgcatc tgcatgtcca tgtgttaaaa agacaccagc
     1561 tacacgatca atgttttctt ctaaatacgt aaaatcaggg attacgacgt cgatccccaa
     1621 caactcattt tcaggatatt ttagcccaca atctaaaata aaaatatcct cgcccacttc
     1681 tgcgacatac atgttttttc cattttcacg aacgccgcct aatgggataa ttttaatggt
     1741 actcacaaac ttcacctctt cttatgacat ccaagtttaa agatgtcgat tttcttcttt
     1801 atctaaatat atgagccatt ccaatgaagc atatgcaaaa tcactatttc tcaacttatg
     1861 gagaatcagc aggaaaatta ccagcacatc cgcgttctga cagttggatg ggcattttat
     1921 tttggatata cttcattaac aaaatggatc ttttgcgaaa cgctatagcc agaatactta
     1981 tataagtatt cagctgttcc ccattattat acaacaaata aactaaatcg ctagtatcag
     2041 caattgttag aacaactatg cacgtaaaaa tccctctgta gcatctagga tttcttttgc
     2101 tattcctctt tcatttcttc ttcgtcggtt tgaaacatac ttttttcatt ttaccacatt
     2161 ttttgcaata actatagtga ctttttatat atacagaacc tcatgttgat ggtgtgcaaa
     2221 cagcataaga tttaagctag ctttaagata ggttgtctat tatcaaatgc atctactagg
     2281 agggatgcaa aatatgaatt ttatgaaacg tgcatggaaa agtacaaaag taaaatgggg
     2341 acgttcattg ttattgtttg ccgtgttcac agccattctt atttttgtgc tagctggcct
     2401 cacgattcga agcgctgcag aagaagcagc gaatcaagca caaaaagaag ttggagcaac
     2461 agtgacttta agtgccaatc gagaagcttc atttaaaaaa caggaacaaa cttcttcaag
     2521 cggttctacc actgaagaac gtccagatcc aggcagtttt tctcttacac cagtttcctt
     2581 aacggacgcg gaaaaaatag ctgaattaga taatttaaag agttattcct ttgaaagttc
     2641 cgcctcagct atggcaaaag atggaataac tgccatcact agttctgatt caagtgaaga
     2701 cagttcagaa actactgatg caggcggtga acctgctgga ggaatgggcg ggaatccgca
     2761 aatgactcaa gcagactttc aaatcagtgg tgtgtcagca actgcacaaa atagtaattt
     2821 ttctgatgga acagcaaaaa tcacggatgg tgaaggaata gatgacagcg acaaaggcac
     2881 aaacaatgta gtcattgatt ctactctagc agaaacaaat gacctggcag tcggagatac
     2941 tttcacaatc acgagtactg aagatgaaga tatcacttat gaaatgacga tcaaaggaat
     3001 ttatgaatcc agcgaaacaa gcggcagtat gggtatgaaa ttcaacttca tgaatccgtc
     3061 gaatacactt tacacttctt acacttttgc aaatgaacta aatgggacat ctgacgataa
     3121 cacgatagat tctgctattt acactctatc tgatccagat aaaatggatg agtttctcaa
     3181 agaagctgag aagctgatcg acacagatac atttagctta caatcaaatg attccatgta
     3241 tcagtcaatg ttggaacctt taaacaacgt ggcaagtttt tctaaaaatg ttgttttact
     3301 agtggctgta gccggtatta tcatacttac tctgatcatt atgattacca ttcgggagcg
     3361 tcggcatgag ttaggcgtct tgctatcttt aggagaatcc agaagtaaaa tcattctcca
     3421 attgtttacc gaagtggcta tttgtatgat tcttgcatta ggagttgctt cgcttagcgg
     3481 aaacgtcgtc gcgaatgccg tgggacagca gctacttgac caacagacag aaaccacgac
     3541 acaaaaccag caagctcctg gcggtggaca aatgccaggt aacagacaag aacaaggcgg
     3601 tcaacgcgat ggtcaacaag gaaccacgaa taatccattt gctgtttctg atcaagtcag
     3661 cgaattggaa atcaatgtca aacctgcaca attgggacta ttagccggag tagcatttgg
     3721 aatcagtctg ttttctgtct ttttagcttc tatagggata ttaagattaa acccaagaaa
     3781 aatcctatta aactaaagga ggaatttgat gttacggaca gaacaattgg gattttggta
     3841 tcaagatccg caagatgcgc tttataaaga tgtagaactg aatttcgaag ctggaaaaat
     3901 gtacgctatt ttaggagcaa gtggttctgg aaaaacgact tttctttcgc ttatttctgg
     3961 actagatgca ccaaaagaag gaaaggtata ctatcaagat cgttcactga acaaaatcgg
     4021 gttaagaagt tatcgtaaaa atgatgtctc gattattttc caagcttaca acttgcttcc
     4081 ttatttatcg gctctagaca acgtcatagc agcaatggaa atcactaaga ccaagcaaga
     4141 gaattatcga caagttgctt tagatcgact ggctcgtgta ggaattgatg aaatattagc
     4201 aaaaaaacag gtgaccaaac tttcgggagg tcagcagcag cgagtcgcta tcgttcgtgc
     4261 tatctgctgt gaacatcaac taatcgtagc ggatgagcct actggaaatc tagatgaaac
     4321 aacttcacaa gatatcgtca aacttttcca agaaatcgcc catgaacaaa atcgctgtat
     4381 tatcatcgtg actcatgaga ttgaagtagc aaaaagctgt gatgaagtct ttgaactaaa
     4441 aaataaaaaa tttcaaaaaa tcgaagttta aaaaacagga taatgatcaa ataaaaaatc
     4501 cgaaccatat ctgtctcgca gatatggttc ggatttttt
//
LOCUS       DARPZF010000105         4462 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.112, whole genome shotgun sequence.
ACCESSION   DARPZF010000105 DARPZF010000000
VERSION     DARPZF010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.112"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(306..836)
                     /locus_tag="SLE65_002756"
     CDS             complement(306..836)
                     /locus_tag="SLE65_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEI8449988.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            complement(1018..1674)
                     /locus_tag="SLE65_002757"
     CDS             complement(1018..1674)
                     /locus_tag="SLE65_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEI8449989.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            complement(1801..2274)
                     /gene="dfrF"
                     /locus_tag="SLE65_002758"
     CDS             complement(1801..2274)
                     /gene="dfrF"
                     /locus_tag="SLE65_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HEI8449990.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            complement(2693..2911)
                     /locus_tag="SLE65_002759"
                     /pseudo
     CDS             complement(2693..2911)
                     /locus_tag="SLE65_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2942..4156)
                     /locus_tag="SLE65_002760"
     CDS             complement(2942..4156)
                     /locus_tag="SLE65_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HEI8449991.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         1373 a          944 c          658 g         1487 t
ORIGIN      
        1 gaaatcaact gtctttctca tatttactat tcaattttca tagtgatata ggtacaattt
       61 atatcactac tgtaaaaatg gggttttgcc ttataaatac agcgttttcc gcttgttagt
      121 gtatagtgtt tcttgttttt tgtgcccccc ttgttagata acgggggctt tgaacggctc
      181 gcaagctcgc cgaaccgccg aagcgaaccg cccccttgca agcatggcgg aaaaatctta
      241 aggattttcc cgccaacgtg gtcggatcgc tccgtcggtt taacagcttt tctgtttctc
      301 tctagttatc tacgcatata aatcaaatcg gttattccgt tataagtctg tgttttacaa
      361 agccttaact ttatttccct gtctatgttg cccaaaagac gaaccccatt tcctaacaga
      421 gtaggaataa cagaaatgta atatttatca atcatatttt tgcttaccaa ctgctgaaca
      481 agatttgctc cgccacaaat ccaaatatcc tttcctgctt cttgttttag ccgttccaat
      541 aataaaacag gattttcact tgtaaaatga atttgttggg aagaattgca ctctttatgt
      601 gttaatacat aagttgtaaa tttattatat acccattctt gcggagaaag ttcagtaaca
      661 acctgatgag aagtattcca ccccattaag acagtatcta tatctttggt aaattctgta
      721 taagtgtcga tgttttcatt gtcatttcca tgaccattta gccaagctac tccaccatta
      781 ccgtccgcaa tatatccgtc aaggctcatg gcaataaata aaactacttt tctcattttt
      841 tctcttttat aaatacaaac aggaatttat ttctcttttt tactcataag ggaacaactg
      901 attgctacaa ataaacccat taaaatccat ggaaatgctg ctcttataaa atcactaacc
      961 atactttatt cctccttaaa ttccaatttc cttagttcta caaactgaaa tttttgccta
     1021 tgaatgtatc ttgttcttta tacgcaaaca ggcttctgtg tgcataatcc aatgtcttga
     1081 aaacggcatt tgaattagtc cacaaatatc tttattacac caataatcaa tcagccaaat
     1141 tgctttttca ttgtcgttta ctacattcaa cgattctaag tatccttttc tttctttcgg
     1201 tatttttctt ttcaattcat cataagataa ccgttcaagc attttctcag tgctttccca
     1261 tacttcgaaa atatataaat ataattcttc cagattaagc tgttttgaaa agtctgcaat
     1321 ctgctgtttc atgagttcat ttcctgttgt aatgataggt gaattgatac gctcttgata
     1381 attgcctgca aaaaatactt gttcatcttc atttatcact gtatgcacaa ctatatcttc
     1441 aatgcggaaa atatgccaaa tagaataagc aatcgtctta ctatgataac catcagcgtt
     1501 tatgaagggg attgagttaa aatcttctct gcataattct tctttgaaag atactaaggt
     1561 ttgtattaac tgacttcgta aagtaagtaa agtatcaata cccctcttat aagtatcttt
     1621 cttttttatt tgtgcctgca ttgttttatt aagttcagac cattccttat tcatattcaa
     1681 tcctctctca aattctgatt ttatcgcccc atacaaactg gaatttgtct tacaacaatt
     1741 tatatatgca taaaaagcaa tatatttatg aaaacaccct aaatccaaaa tttactcaat
     1801 tcattttttc cttacataaa atgttctcgt atatttcact tcctcaccaa gtgtttcccc
     1861 tatcaaaact tcaaaatcat tgatatcaaa ttctggaaag aatgtatctc catcttcaat
     1921 atttaaatct acttctgtga tatacatttt atctactatt tgcaaagctt ccttaaatag
     1981 tccatatcca ccagatatgt atacatctcg tcctttagcc aataataatg catcttctaa
     2041 tgatttaact gaaactaaat tatctccttg atactctgtt gtggtggaaa caacaatatt
     2101 cattctatta ggcaacggat gaccgatttc ttcataagac tttcgcccca taataaccac
     2161 attacccgtt gttaactctc taaattgctt ttgttctccc tttattttcc atggtatatt
     2221 accattcttg cctataacat tattctttga cctcgcaaca atcaaaccta tcatctattt
     2281 catcctccat aatatgatgt cgtacctgtg attccatcaa gtgcaccaca tcttaacaaa
     2341 ctcaaaatta tctcgaacta accagctcga caaattcctt ttttgtcttc atctgcatta
     2401 tatcatattg ttataagcat tgccatttct tttctgcttt tgaaaagtta cttatcagcc
     2461 tatgttttgt aaagggtgat attcagcatt tctcacgcaa caagcccttg acaaaccata
     2521 gactaataag ttttaaggta atcaagcaga aatgaaatag tctgctgttt cacggcaaca
     2581 aaaaagagat accaacacac ttatgtagta tctcttagtc tagtagcaat attcttttgt
     2641 ttgcaagcag gtaaacatgg gctgtttctt aatatctttt tgtttgggaa acaccttttt
     2701 cccatccttt caccgttgcc atctctgctg cgcacaatgc cacagggata aaccatagca
     2761 aaccgcctaa taacaagaaa aatactaagc tgaagcctga ggtcgcgaat gtgggatatt
     2821 catataatga aacgaccatt gagatggtca tagccaaaaa gccaaagaac gttaattttt
     2881 ttgcaggaat tttcgttttg ctttgttgca tgaatcttcc tcttttctat ttgaatttgt
     2941 ttcaattgag tttgttgcca aagaagaaaa agtccaatcc ttcttcttgt tcttcttttg
     3001 tagtagtgat cgttgtaaag tgcatcgccg attttaaaat cactgttgtc agcacatagg
     3061 catacacggc agtaatgatg acaccaatca cttgaatccc taagaagtac cagctgcttg
     3121 gattcgttag taaatggctg ttagatgcaa agatccctat cagaatcgta cctgtgaatc
     3181 cgcccatgcc atgaacaccc cacacatcaa gtgcatcatc ccattgtttc tttttacgaa
     3241 aatcaacagc agcatgacag acgatacccg caatgatccc aatcagcatg gcactttttg
     3301 cttctacata accggcacaa ggcgtaatgg ctgccaatcc agcaacggat cctgttagta
     3361 cgtcgacaaa atcaaagcca tttcctttta cttttgcaat gatcagccaa gtaatcatcg
     3421 caaatgcaag agcgatgaat gttgaaccaa atgcattgac tgcttgttca tctgctcgaa
     3481 gtgcaccacc ggaattaaaa ccgaaccagc caaaccaaag cagtcctgta ccgatagcag
     3541 ctgccataag actgctatgc tgacttcttt ctcctaaagg aatctttctt tgaccaagtg
     3601 tgaggataca tgctaaagag ccgaatccag ctgtcgtgtg gatgactgct ccaccagcga
     3661 aatctctaaa tcccatctga tccaaaaatc cgccacccca tatccagtgg caaacaggga
     3721 aataaatcag cagattccaa aaaataacaa gtataatata gccttttaaa ttcaatctcc
     3781 ctgcaaaagc tcctgtcatc aaaggaacgg taatcacgat aaacatcagt tggtaaagaa
     3841 agaacattaa aaatggaatc gttgcaccat gaaacatgtt ggggaagctt gtaacatgtc
     3901 tcatcaaaaa gaaatctgcc gggtttccaa taacaccgcc gatatcccgt ccaaaggcca
     3961 atccgaatcc accaaatacc cacataatcg ttgttatccc aacggagaga aaagattgag
     4021 acatgatcgt tagtatatta ttcttccgtg ctaatccgcc gtaaaaaaaa gctagaccag
     4081 gagtcatcag gcaaaccatt gctgtacata aaatcatgaa tgctgtatct cctgtattga
     4141 taggtaatgt attcattttt ttcgcctcct ttctacgatt acgagtataa aagaaggtgt
     4201 agttgttttt ttcttctgtt tttttgaatt aatacttgca tttataaaag acagacaatt
     4261 aataaaagct tgatgtgttg tgctcttttt cgtttttcac acaaataaag acaaaaaata
     4321 aacggtcttc tttttataga aaaccgttta ttttcgtctt tttttatttt taaagatatt
     4381 ttttcataag gaataaagaa tacttcatat aaaatatata aaaaagaacc gcagcgagtg
     4441 tcgctacggt tctcaaattt gt
//
LOCUS       DARPZF010000106         4430 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.113, whole genome shotgun sequence.
ACCESSION   DARPZF010000106 DARPZF010000000
VERSION     DARPZF010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.113"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(543..2048)
                     /locus_tag="SLE65_002761"
     CDS             complement(543..2048)
                     /locus_tag="SLE65_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEI8449992.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="SLE65_002762"
     CDS             complement(2045..2731)
                     /locus_tag="SLE65_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8449993.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="SLE65_002763"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="SLE65_002763"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEI8449994.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1238 a          919 c          729 g         1544 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat
//
LOCUS       DARPZF010000107         4337 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.114, whole genome shotgun sequence.
ACCESSION   DARPZF010000107 DARPZF010000000
VERSION     DARPZF010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.114"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(692..985)
                     /locus_tag="SLE65_002764"
     CDS             complement(692..985)
                     /locus_tag="SLE65_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HEI8449995.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(1388..2566)
                     /locus_tag="SLE65_002765"
     CDS             complement(1388..2566)
                     /locus_tag="SLE65_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEI8449996.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            complement(2670..2984)
                     /locus_tag="SLE65_002766"
     CDS             complement(2670..2984)
                     /locus_tag="SLE65_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8449997.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            3091..3306
                     /locus_tag="SLE65_002767"
     CDS             3091..3306
                     /locus_tag="SLE65_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8449998.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(3606..3848)
                     /locus_tag="SLE65_002768"
     CDS             complement(3606..3848)
                     /locus_tag="SLE65_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8449999.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(3835..4263)
                     /locus_tag="SLE65_002769"
     CDS             complement(3835..4263)
                     /locus_tag="SLE65_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEI8450000.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFLI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
BASE COUNT         1375 a          826 c          650 g         1486 t
ORIGIN      
        1 atttttaaat aaaaaatact ctttttttac gattattgaa aaaaaaagat aaaacttgat
       61 taattgaagt attgcttaaa tttggaagct atgagggaag aataaaagag ttaggacggg
      121 attatctact atttttcttt gttttaaata tttgttatct ttgaacataa aagagaaatg
      181 tgtcgactgc agtgttgtgt ccctcatcac gaataaacgg tgttcaatta gctgatcttg
      241 tattcactta aaaaatggta aagtacgagt tgctattccc cattttcaat tttctaacgc
      301 tcaggacaaa atactgtttt cacaacctca ttggaataaa agcatatata ttgtttcaag
      361 aacgaaatct tgttatcttt ttaaagggca tctgtccaaa atctaatttt aggaggtacg
      421 ttttggtatt tattcgtaca aataaaagag aattatcttt attcatgtaa cgcatccaat
      481 tgattttttc atgtacgctc ctggaacgat tttactgacg attgcttatt taactgcgaa
      541 tcgctcatta gcttttatca tagctatcca tattttgaat aacgttcttg gctttgtatt
      601 atagatacag atgacaaaaa aagttcaagt atgcggtgta gaaccaatat cgcatacttg
      661 aacttttttc aatgagtata aattaaaact tctaattttc aattcccatc atctgatatg
      721 cccgaccgtc tgaacttctt ttgaaaaagc caaatgtgat tagataacgt ctttgttcga
      781 cataatcgcc actagaaaat acgttcagca gtatcgaatt aacctctgtt tctgtataag
      841 tcactccatg gtcaaagcgt ttcaagactt ctttcaatag gatgtatttc ttttttgttg
      901 aacttggtac ttgttttact tttccatcat tcatgaatgt gtctaaaact ttcatctttt
      961 cttgctccgt ataagtataa accatcttct ttctcctttt gattctaaga atactccatt
     1021 tatgttagaa tattctggat tttttattaa agcggttact cttaagaaag atattatcat
     1081 agtgctcttt tttttactac tacttatagg tagatttatt ctaatccatt attctcccct
     1141 accaataatt aaagaaaaaa ctggatcagg gtgttcaaat tacatgctaa gaaaaaagaa
     1201 cccttgaata ccaagggttc tttctcagtc tgataacaat gattaacgac ggatttcttt
     1261 gatacttgtg aaaagtcgtt aaagtattga tataaaagga tttttattac ctctgactac
     1321 atattgacta atttgttaaa aaatcgtttt tcaagaatcc tgtaatacca gtgctttcac
     1381 cgttttttta actctctaaa gaactaaaag caatcagagg ttttaccttt tcatttgacg
     1441 ttaagtggcg ataaattttc gaagttgttt ggtcagtatg gcctaagcga tctttcaaga
     1501 cttcccagct acagtgttcc gctactaagc ttgccattgt atgacgagct aaatgagtat
     1561 gaaatggctt attaattcct gagcgattca cgcaccgttt gacgtgatca tttacatact
     1621 ctcgacgata aggaacacca cgtttactag aatcaagata cacaaacaaa tatgtttctt
     1681 ctataataaa cctgtaatgt tgcctcatct cacccaaagc cttaatcaac tgttgtagct
     1741 tttccataac tagaggagtt actagaactc gtctagcaga actaactgtc ttagtagttt
     1801 caattcgaaa atccttactc ttacctttaa ctgccgtttg cttatagaac agaatttcat
     1861 ttcttttgaa atctatatct ccaggctgta gagcaagcgc ctcgctgact cggcagccag
     1921 tgtaaaatag aacatggaaa agtacagaca tcggtaattc ctcatgaaca atgccataat
     1981 tcaaaaaagt tctcaattca tcgacagtaa gaaacttgtc ctcaatatta tttatggctt
     2041 cttttaaatc agttaccgtt aactgatatt ttggcattct cacagacttc attggatttt
     2101 cacttatcaa attctttctt tgacaatatt taaaaatcat atttagaact tgaataagtg
     2161 attgtaaact atttttggca tagccaacat ttgttccatt aacgccacat tcctttaagg
     2221 taaaaagcaa ttcttgaagg cactctggtg tcaaatcaga caacttttta tcaccaatcc
     2281 atcgaacaat aatttttaat tgttcctctc gcttatcata ggttatttcc ttttgttcat
     2341 ttaacgaacg gtaatattgg aaccattgct cacctacaac actaaacttg tcattgcttg
     2401 caacaatttt tttcttaagc ctttgttgtt tctccatttc cagataagcg agttgcgcct
     2461 cacgttttga attaaagcca cgtcttgttg ttcgatatgc ttgaaagtac catgtgatcc
     2521 taccagtaga actgatttgc ttcttgaatc gatctgtttt ttccatttat tgattcctcc
     2581 tattttgaag gaacccaaca agcagaaacc ctttggaaat ctttctatct atgtcatcat
     2641 tgtaccgcat cttagaaaga aaatgtaact tataaagatc gaagtagtcg caatttttct
     2701 cgatagtcat tcgaatcact ctttctcatc cattctaaaa catcatcacg aaaatagtgt
     2761 cctcgaatcc cgtaccaaca gggaggaaac tcaccaagtt ttactaaacg gttcagtgta
     2821 ctatcactta tctgaaatag tcgctttaaa tcagtatttg ttaataccag aggtaaatga
     2881 ctgactgcaa gcaatttttc cgtgtaatct tccagttttt tttgtaaaat tgaatagaac
     2941 tctatttcca gagaattaac atttgtttta acttccaact ccatcaccct tctctctcaa
     3001 aatcaaaacg accaccacgg taccccttaa aattgtaaaa aaacactcca gtactccatc
     3061 aaaacggact agaaaagagg aatttttaat atgaaacaag gaattgcaga cataaaaata
     3121 attaaagaaa ttcttgaaaa atctacggct aatgcaatag cattcggaac aggaatcaac
     3181 ttgagtacag taaaaaaact taaaagtgga gagagagctg aagaaaaatt aaatcttgcc
     3241 gatgctatta aaatcacaga atttggcatg aaaaatatgc caaccaaaat cgaaatatgg
     3301 aaatagtagt ttttctgatc tatcagctgt tttgccaaag cacataggaa tctcacctcc
     3361 ccccagtaat ggcgggccga tttggttacg gaagtatcat tatcgtagtc gcgattctca
     3421 tattaaaatt tgtcgcttaa aagctaacct tgtcatggcg taactagaga atcaaaatct
     3481 acatgtactg atagatttgc tattcatttg tcaaagagcg ctaggctatt ttcagcctat
     3541 ggaaatcctt tattttgacc cgataaaaaa cttccataga atgaaaagga aagggaaaaa
     3601 atactttaac gagttgtatc aaattcaagt atcttctcaa tcaattttgt ttccagttgt
     3661 ctacgcatat attcatctac atacataacc attccttttt cttcttcata aactggtttc
     3721 atggctaacc gtgaaatata attttgatat tttgacagaa cgatggacat ggcaattgaa
     3781 tcaccagaag ctgcggcttt gattgtcgtt agtggtatga atggtatata tcgtttattt
     3841 tgcttcatat ttgacaccca aatactttcc tagctcttcc aaagccattt gtcgttggta
     3901 ccaaacactg ccgagacttt tcccaataat atcgccaatt tcacgatcat taagaccgat
     3961 gaggaaggac ataaaaatga tttcttgtct ttgactaggt aatgctgcaa tcgcatttgc
     4021 caactcctca ttggaaataa agattttcat accaaggaca ataaaagtac cactactatt
     4081 caaatttggt tccaaataat agaactctgt acctaaccct ttttgttcca atatttccat
     4141 tgatatttgc cgttggcgaa atctagcgta cttcttttga atatttaacg cctcattgca
     4201 gactactttc ttacaaaaac tgtcaaacgt atgttgaatg tgggtttcct ctgagtcgcc
     4261 cataatattc tccccctcaa aaaattcatt caactcgttt tacttctatc cctttccatt
     4321 attactacaa tctagga
//
LOCUS       DARPZF010000108         4317 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.115, whole genome shotgun sequence.
ACCESSION   DARPZF010000108 DARPZF010000000
VERSION     DARPZF010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.115"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            148..1137
                     /locus_tag="SLE65_002770"
     CDS             148..1137
                     /locus_tag="SLE65_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HEI8450001.1"
                     /translation="MKKKKQDLINGTFREKKKNLKKVVAFSDNRISPKMRELMTGCGS
                     YLEFIATIDKEKKKLVQAHFCKNRFCPLCAWRKARKDSMMLSIMMQAIAEEKQYQFIF
                     MTLTTPNVKAECLNDEIDLFNHALKKMFMRKRVKTSIKGYVRKLEITYNKKRNDYNPH
                     FHLILAVNKSYFTDKDYYIKQSEWLDLWREVTGKTGINPDGTDEITQLDIRKVKGFQQ
                     EKAVQEVAKYSAKDFELTESQEVFDTFYHAMKGRQLITFNGVFKEYKKKYESGDLDRY
                     KKKDENEYFWFLTASWMRKESKYAVDYREMSADERNYFSGMYVDEKSVEGENE"
     gene            1134..1553
                     /locus_tag="SLE65_002771"
     CDS             1134..1553
                     /locus_tag="SLE65_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450002.1"
                     /translation="MTDSTDKMTIKALADELGITKNTVRNYLVKAGYDLARYKKNGII
                     LLDKELIGVARSIYRSKGGQLTGHLPVNSTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            1532..1870
                     /locus_tag="SLE65_002772"
     CDS             1532..1870
                     /locus_tag="SLE65_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450003.1"
                     /translation="MVAILEVRCDMDKIDLREETVNRIEVMYERLADYLNLSDEDNYS
                     EMLERMMDVLNSVINADLAKSSVLTNEFVHKHLAQTTDEAEKEFWLKLMSHIMQLNQI
                     SVINSKEKGM"
     gene            1874..2236
                     /locus_tag="SLE65_002773"
     CDS             1874..2236
                     /locus_tag="SLE65_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450004.1"
                     /translation="MGMTLADIKVQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFESFADFERWLSSISDDQQHEKSVDNEWLADEKSAPSERDYPNEYDGLLGVIPSKK
                     SQMNESKFMSIFNDVNLR"
     gene            2458..3865
                     /locus_tag="SLE65_002774"
                     /pseudo
     CDS             2458..3865
                     /locus_tag="SLE65_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
BASE COUNT         1506 a          605 c          988 g         1218 t
ORIGIN      
        1 aaaaaaaaag attgcttttt cttccctagt attttatagt tttaattgac tagaaaaaaa
       61 ctaaactaga aaggagagca atctattttt tgttatcggc ttttcagcct tttttgtata
      121 caaaatttgt agattcagta tagcaagatg aaaaagaaaa agcaagattt gattaacgga
      181 acatttcgag aaaaaaagaa aaatttgaaa aaagtggtgg catttagtga taatcgaatt
      241 tctcccaaaa tgcgtgaatt gatgacaggc tgtggttcat atttagaatt tattgcaacg
      301 attgataagg agaaaaagaa attggtccaa gctcactttt gtaaaaatcg tttctgtccg
      361 ttatgtgctt ggcgtaaagc tcgtaaggat tcgatgatgt tgtcgattat gatgcaagct
      421 attgcggaag aaaagcagta tcaatttatt tttatgacgt tgacgacacc gaatgtaaaa
      481 gcggaatgtt tgaacgatga aattgatttg tttaatcatg cattgaaaaa gatgtttatg
      541 cgcaaacggg ttaagacttc gattaaaggc tatgtgcgaa aattggaaat cacgtacaac
      601 aaaaaacgga atgactataa cccgcatttt cacttgattt tggcagtaaa taaatcttat
      661 ttcacggata aagattatta tatcaagcaa tcggaatggt tagatttgtg gcgggaagtg
      721 accggaaaaa cgggaattaa tccggatggt accgacgaaa ttacccagtt ggatattcgc
      781 aaggtcaaag ggttccaaca agaaaaagca gtacaggaag ttgcgaaata ttcggcaaaa
      841 gattttgaac tgaccgaaag tcaggaagtg tttgacacat tctatcatgc aatgaaaggt
      901 cgtcagttga ttacgtttaa cggtgtattc aaagaataca agaaaaaata tgagtcgggt
      961 gaccttgatc gttataagaa aaaagatgag aatgaatatt tttggttttt gactgcttcg
     1021 tggatgagga aagaatcgaa atatgcggtt gattatcgtg agatgagtgc tgatgaaaga
     1081 aattattttt caggaatgta tgtcgatgaa aaatctgttg agggggaaaa tgaatgactg
     1141 attcaacgga taaaatgaca attaaggcgc ttgctgatga actaggaata accaaaaata
     1201 cagtgagaaa ttatctagtc aaagccggat atgatcttgc tcggtacaag aaaaatggaa
     1261 ttatcttgct agacaaagag ttgattggtg ttgctcggtc aatttatcgg tcaaaaggtg
     1321 gtcaattgac tggtcattta ccggtcaata gcacgggcag tgattttcct ttggaaaaag
     1381 agaatgagtt tttgcgtgat caattagctg agaaggacaa acatatttct gaattaacag
     1441 aaatgattcg tgatcaacaa aaattgaccc tgcttcagca acaaaaaaac gatcagttgt
     1501 tactagaaaa tcaagaatta aaaaatcgaa aatggtggca attctggaag tgagatgtga
     1561 catggataaa attgatttga gagaagaaac agtcaataga attgaagtga tgtatgaacg
     1621 gttagctgat tatttgaatc tttcggatga agataattat agtgagatgc ttgaacgaat
     1681 gatggatgtt ctcaactcgg ttatcaatgc tgatctagca aaatcttcag ttttgactaa
     1741 tgaatttgtt cataagcatt tagcgcaaac aactgatgaa gctgaaaaag aattttggtt
     1801 gaaattaatg agtcatatta tgcagttaaa ccaaatttcc gttattaatt ccaaagaaaa
     1861 ggggatgtag tttatgggaa tgactttagc agatattaaa gtgcaagaag aaaaattaaa
     1921 aaaagaacag gcgaaacttc gccaacagaa gaaacgattg attgagaaag aaaatgctgc
     1981 aatgggcaag gctcttcgca agcgttttgg gtttgaatct tttgctgatt ttgagcggtg
     2041 gttatcgtca atttctgacg atcagcaaca cgaaaaatca gtggataatg agtggcttgc
     2101 tgatgaaaaa tcagcgccaa gcgaacgaga ttatcccaat gaatatgacg gcttactcgg
     2161 agtgataccg agtaaaaaaa gtcagatgaa tgagagtaaa tttatgtcaa tttttaatga
     2221 cgtgaattta cgataagcta ttattttgcg tgaagcaaaa taaagcgtaa aaggagttga
     2281 gagcgtgaca cgctttcggc tccttttttc gttgtcactt gtgacagcga aatccctcgg
     2341 agagcgtttg gaattgtgac agtcatgtca caattaggaa aacgttactc tttgacaaag
     2401 agtaacagaa aggtttacac tctttttatt agcgacagcg cgaaggaggg gtctaacttg
     2461 gggtttagta tttcgttcaa aaagggaaca aagaatacaa gcatttctca taataatcgt
     2521 gagttaactg atagccaaaa aatcaatgac tggcataagc atattgattt cacaaaatcg
     2581 gatgaaaata tctatttgga acaaacaaat attcgtgaaa aatatgaaga attattcggt
     2641 gaagccgtag aaaaatataa tgcaaagcag aaaagagccg atagaaaaat cgaggactat
     2701 ttagcaaagg ttcgcaagga taaaaaaatt ggaaccacag cgagaattta tcgtgcaaat
     2761 tggtactctt gatgattttc gtactactcg tgatgatggt tcttctactg gcatatcgga
     2821 acaacaagca gaacaaaatc gagtgattgc caacaaaatt ttagttgagt atttcaaaga
     2881 atttaaagaa cggaatccta gtttatccgt ctacaatgct gttattcata atgacgaagt
     2941 aagtccgcac ctgcatttga atattgttcc tgttgctgaa gggtataaac ggggtgttca
     3001 aaagcaacca agttttaaca aagccttgca acagcagggt ttacgagcag ataaagagaa
     3061 tggtcgagtg atttggaata attttaggaa tcaggaagtt gagtcaattg aacgtttgat
     3121 ggcagatttt ggttgggagc gtgagttagt cggtactaac aaaatcaaag atgttcacga
     3181 atataaagaa atcatgagcg agatttcaga attgcgtcaa acggccgtaa aagagcgtga
     3241 gagcgtttct gatgagttgg ggtatatttc taggcaaaga gaagaaaacg agcgagaaaa
     3301 ggctctggtg gcttctgaga gagcaaagat tgaagaagag aagaaaaata tgctgaatgt
     3361 aaaaaaagag atggcggtca ttttccaaaa agatattgtt cctttagaaa gtttcaagag
     3421 gcttcctgat ggttcgtatc atttatctgg gaatgatttt gttgatttgt atcaacgagc
     3481 tacgagagca acaaatgcca agagaaatgc tgataacatg agtgagcaat atttacagat
     3541 gcttgagcaa aatacagaat taaatgagta tgtagctaca ttggaagaag agcgtcattt
     3601 gtctggtaga aaacaattag cagatttaca agtggaaaat aaaaagctga aagaagaaaa
     3661 tcgctcttta cgccagcgtt tagagcgatt aaaaaaagca tttcaaaaat cgatcactcg
     3721 tttgtctatc cgttttggtc ttgcagaaaa ggatatgggg ctttctgagg aattagaagt
     3781 attagagcag gagaaaacct tattttatcg tcaaaacgtc tcacagcata aattagagcg
     3841 ttctgaagat gagatcgagt ggtagttacg atgtgcagtc aacggtaccg gaggcggtct
     3901 gtgccgagga taaggagttg acggctaaac cactagccta ttaagctgac atttgctaaa
     3961 aaatggcaag tccatttttt ggccaaccta gcgttagcga aagtttgggg gcgccctttt
     4021 caaagggagc ggttttattt ttgcatgact aagaatgagt gggaaaaact taaccgcatt
     4081 tctaacaggc ggttaaagta tcaaagtttg acccttccct taaaaatgca gtggtcaatt
     4141 gaccgaattt tatgcagaag tgggtttttg agttttgggg tttgaaacga gaaaaaagag
     4201 gtcgatttcg acctcttttt ttgatgtttc ttcttatctt gatactatag gcaactattt
     4261 ctgcgaagaa atcggggcta tagtatgggt ctatcccttg tggctctaag gaagaac
//
LOCUS       DARPZF010000109         4157 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.116, whole genome shotgun sequence.
ACCESSION   DARPZF010000109 DARPZF010000000
VERSION     DARPZF010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.116"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            179..775
                     /locus_tag="SLE65_002775"
     CDS             179..775
                     /locus_tag="SLE65_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEI8450005.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            899..2698
                     /locus_tag="SLE65_002776"
     CDS             899..2698
                     /locus_tag="SLE65_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEI8450006.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2976..3188)
                     /locus_tag="SLE65_002777"
     CDS             complement(2976..3188)
                     /locus_tag="SLE65_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450007.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            3650..3799
                     /locus_tag="SLE65_002778"
     CDS             3650..3799
                     /locus_tag="SLE65_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450008.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            complement(4052..>4157)
                     /locus_tag="SLE65_002779"
     CDS             complement(4052..>4157)
                     /locus_tag="SLE65_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEI8450009.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         1228 a          707 c          729 g         1493 t
ORIGIN      
        1 tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga gatcaatctt
       61 ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa aatggcgcag
      121 ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt gatgaataat
      181 gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat taggcctatc
      241 aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga atgcgttaag
      301 aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca tccaaatcct
      361 gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg tcctgatatt
      421 tggcccttat gctggattta tctataacta tattggaatc tgcattggtt cgattatcat
      481 ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta gcgataagac
      541 atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc tgtttgctct
      601 agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg gattgacaaa
      661 catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt cgattttctt
      721 atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg gataatattt
      781 attttgtaaa attagtcatt gattgacaat gttaaatctg ggaaagggtc tgcaaaacac
      841 actgcaccct ttcctttttc attagatttg cgctacaatg tgaagagcag gtgataggat
      901 gaattatttg aaacgtagct taggtaatgc ttgggacttt ttaaaaggaa cacaagctta
      961 tttccgtgat gtcttgctga tgcatggctt tattttattt atttgtttac ccttattgag
     1021 cagtacgacc cgttttattt tacaccgagg ggcaattgac tatttgtctt atgacaatat
     1081 tccttcaatt ttttctcaac atcctggggt tctactctcg ttaatcgtag ttttgatgac
     1141 gattttactg ttagtttatt tcgaatttac ttttcttttg atgagtgttt tttttattaa
     1201 aaagaaagaa ccaatctctt tgaagcaact cttacacttg acgatacttc agctgaagaa
     1261 agtgagaccc attacttttt tgtttttcct tgcttatttt ttattgattc taccgatcag
     1321 cggattaagt tttaattctg atctactgtc aaaaataaaa atccccgctt tcattatgga
     1381 ttttattttt gctaatcgtt ggatcatcgt cagttccttt ttactcgttt atattttcct
     1441 tggctatatt gggattcgac tgatttttgc tttaccggaa atgattctac gggatcgtcc
     1501 ttttcgagca gccattcggg aaagctggtc attgaccaaa tcgcgtcttt tggccatcac
     1561 gggccaattt attgtgattg gcggtacgat tttactcctt tcttctttag gatatatcgt
     1621 tgttattttg gcacaaagta tggttgaaca atttttccca gactatgcat tgatcagcgc
     1681 tgtgtttgct atgacgcttt tacaagggat tttattattc aatatcgtga tgtctaccgt
     1741 agggattttt tatatcattg ttgatttcat ggatgacgaa ggcttcttgc ctgagatccc
     1801 taagtggttt atcccacaag cccccaactt gcgtttctct gcgctgaaaa acactggttt
     1861 gactcttttt gcagtttttt tcggtattgg cgtctgtctt tacaatatgg attatctgac
     1921 ttcagctgtt cagacaaaac cagtgactgt ctctcacaga ggtgtgagta cccaaaatgg
     1981 ggcgcaaaat actttagaag cacttgaaaa aacaagcaga gactatcatc ctgattatgt
     2041 agagatggat gttcaggaaa caaaagatgg tcatttcgta gtgatgcatg atgcaaatct
     2101 tcgtcactta acaggggtaa atggaacacc acaggatctt acattgaaag aattgacaaa
     2161 tcttacagtt actgaaaacg gagtgcaagc ccctgtttgt tcttttgatt cttatttgga
     2221 aaaagcacat aagctaaacc aaaaattact tattgagatc aagacctcta aaaaagattc
     2281 ggatgacctt gtcgaacgat ttgtccataa ataccgcaaa gttatcttag agaaccatca
     2341 tattttgcaa agtttgacgt accaaaccgt ttcagattta aaagaagcag aaccaaactt
     2401 ttatgtgggc tacatcttac ctttcaatat tgttgggccc cctgtgacgc ctgctgattt
     2461 tctgacaatg gaatatagta cgatcaaccg taacttcatt aattctgccc accaagacgg
     2521 aaaagaagta tatgtatgga caatcaacga ttcagatgct atgagtcgca tgatgtttta
     2581 tggtgtggat ggtatcataa ccgatgagat gggactacta aatgaaagtg tgaaacaaac
     2641 agatgaagaa atcacttatt cagataaact gctaaatttt gttttgggag tcggctaatc
     2701 aaaaatcgtt aatgaaaaaa gtctttatac aacaaaaaac gcataacctg ccaccgcagg
     2761 tatatgcgtt ttttgtttga cgctcataat gtgtgcttaa ctttctcttg attccttcat
     2821 cgcacgaaca atagctaaaa tagcaggaat tgcagagatc actgcaagaa taattcccat
     2881 tttccctgaa ctttttcttt ttggcatatc ttctcgctcc cttctgtctt tatttatatt
     2941 ataagggagt tcttgcgaat tctcaaaaat actgtttaag aaaccaattc agcaggtgcg
     3001 ctaatatcac agaattttac gagcatgcga tacttgcttt cattgataag ttgatagtct
     3061 cgttggtcat aactttcaac atacacgaca gccgtgttga tatatgtacg ttcaatacag
     3121 ccgattagtt catgagatac tccgatcggt ttgcatatat aagatcttcc tacttctgct
     3181 tttaccattt cattccctct tttctttatt tttattttgt tttttcttta ttttataata
     3241 acaaattacc ttgtatttga aaacgttttt atccattttt ttatttttta ttttgagtat
     3301 ctttctgctt tttagataac tattttttaa cacgatctta gacgttgtga caaaaacgtt
     3361 tgtttatatt cctatgttgt tcgtgcgttt ttttctttat attgctaagt tatttataaa
     3421 gaggtgagca tatgatttat attcaagcaa tagtatttgt aaccttgatg attgggctac
     3481 ttatcggatt aaaagaaaat agctaaacca tttaagaaaa aataaataag gaaaatgata
     3541 aatgcttttt aattgcatca aaaaacgtac gatgctaaac ttggtataag ttcgaaagtt
     3601 taaaggaaac tttcaagaac taaattacat tacaaaggag atgaatttta tgacgtttac
     3661 aaaaacaaat atgcaatacc gcgtagcttt tgatacaact tctaaccgtt ttatggcgat
     3721 tgatgcacaa aacgaaaata acgttgcgtt tggtattaca atcgaacaag cagtccgagc
     3781 attaaacgaa tctagataag gagtgaacca ttccaaatgg cgactgatga gatctcggaa
     3841 aatcaataaa agacgtttgt aacggtaatc cgcgacaaac gtctttttgt attcattaca
     3901 tatatttgga aattgtctct ctttatctct agacctaaac aaaaacacaa gttctaatat
     3961 caaccatctc gttttttatg acaattttgt tagctgtttc gatgataata ttccgttatt
     4021 atctgtataa tatttaatat aatcttaatt gtcaaattaa gttagacaga tcatcaatac
     4081 ttacgtaact caaaaatact tccaaaggtg ttcgataatc cagtgatttt ctaggaatat
     4141 tatttcgttt agatgcg
//
LOCUS       DARPZF010000110         4139 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.117, whole genome shotgun sequence.
ACCESSION   DARPZF010000110 DARPZF010000000
VERSION     DARPZF010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4139
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.117"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(560..1600)
                     /locus_tag="SLE65_002780"
     CDS             complement(560..1600)
                     /locus_tag="SLE65_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEI8450010.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1949..2275)
                     /locus_tag="SLE65_002781"
     CDS             complement(1949..2275)
                     /locus_tag="SLE65_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450011.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2262..3065)
                     /locus_tag="SLE65_002782"
     CDS             complement(2262..3065)
                     /locus_tag="SLE65_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEI8450012.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3418..3708)
                     /locus_tag="SLE65_002783"
     CDS             complement(3418..3708)
                     /locus_tag="SLE65_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HEI8450013.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3844..4023)
                     /locus_tag="SLE65_002784"
     CDS             complement(3844..4023)
                     /locus_tag="SLE65_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450014.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
BASE COUNT         1275 a          699 c          582 g         1583 t
ORIGIN      
        1 ccgttgcggg taataccgta acactgaagg gcacgcatta aggcgtcatc ttaatgcttt
       61 cctgtaggac actgacggag attaccagtc tcccgagcct tacaggggcc tttctttttt
      121 ttgtattttc aattatcaca atttatcgtc caaaagtgca gaacgaaaat caattcatca
      181 caagcatatc agacaattaa atttaaaaca actaaaaata tacaaaaaag tgtaattgaa
      241 tattagcagc actgcctgaa aagaagtaat atcaggcttt tcagcttggg gaaataagtg
      301 aattacctct cttcatgaat tattataact caaaaaagca catatgcaaa cactagttcc
      361 ctattttttt gaatgaaaaa taactaaaat atctaacgat tatgacttta aaacctacgt
      421 ttgtgattgt tttcataaac ttttaatcta aaaactccgg aataatagct atttatttgt
      481 aacatttgta ataaaattaa aatcataaaa aagttctaat ttaaaattga tcatttttat
      541 agtgatcgct ttttatcaac tactctagcc aattttccgt actaactgtt ggtaattcgt
      601 taaatgtttc tctttgttcg tttgcaagct ttgccgcaat agctttttcg acaaaccaat
      661 tttttacata aacgaaaatt agattctgca aattgtttac tttttcagtt ttttgttttt
      721 gataagcttt cagcaaagtc atatataatc ctttgtcagc atcaattcca taagattcca
      781 gttcttcata aacaacaact gtttgctcta attcttcagc ttttttcttt gcattatgaa
      841 tagtttggac ggttttttga gcgtcttcgt aagtactaga aaatgttttt atcaagttta
      901 atacattttc tggtacaaat gtatttatac tgtcctcttt catgatgtcg acgaagttat
      961 ctagtaaaac ttgattttgt aactgatcag tttcagtgtc tattatgtgt ctattagtgt
     1021 ctatagaatt agaatagaat agattgtctg cgattttcgc aattacggtt gagtccttga
     1081 tatgactgga ttttgccgta tttgcgattt tcgcaattac ggtggtatca ttgatttctc
     1141 gcggttttgc cgtatttgcg attttcgcaa ttacggtggt atcagtattg tcttcctctt
     1201 ccatgatttt aaagacgtct tgattcgtta cttctggctt gcctaagtac aataaattag
     1261 gcatggattc aatcttaccg tcacgtttat ttactcttcc tctcttctgt ttcagaagac
     1321 ctgctttttc taattccttt ttgattttag atactttacc ttcgcggcat tgtaacaatt
     1381 tcattaattc ttcaactgtg aatatgaaaa atatattatc atcagaatct acccagttat
     1441 ttttgactga ataatcaaat cgatctttaa gtagcatata agcaattttt gcatcatttg
     1501 atagatccat gtatttttcg ttagtaaaaa ataccttagg catttgataa tatttttcac
     1561 gataaatttc ttttgatttg taataattaa aatcattcat agccaatcct ctttctgtag
     1621 gatagcgttt tgttcaaaac tatgttacaa tgaattaaac aaatatatct atccactata
     1681 tatttttcta ctgctgataa gtcgccaaac tttgttaaag cagtagtctt tttttatctt
     1741 tttttagttt accttaaaaa ataaattaaa gcaaaccgct ctatttcaag gtttaagctc
     1801 atagtaacta tatcacgata ttacaataat attatatcac gatatcgtaa tattacaata
     1861 tgaagataag cgacttatca gctttgatac tactgatttt tataaaaaaa atatcacgat
     1921 attatgatat cgtgatattg aatgtaaatt aaattttatt ttgtttcttt gctagtttat
     1981 atccttcaat caagtattct tcaggtatgg actttaatag cgcatcttct ataacgtctg
     2041 gtttactttt gtctgattca gcaatagtcg tccaatattt gagtgctgac attagaattg
     2101 gatttatacg aatgctatct gctgttctta cactacttcc ttgatctttt atgactttac
     2161 ttatattttt cttggttaat tcgatttctt ctacttcttt tgatttaaaa ttctttttat
     2221 ttttatttcc tagtaatcta cttactgcag cttgactgcg attatcttct gccatcaaaa
     2281 tcaccaactt cttttaaata ttcttctgta aatgctttat agtcatcttc agctgttgag
     2341 ggtttattaa aattgattag atctgatcca gcagcttgcg cttcgtcaac ggttattgtc
     2401 ctacgaatat aagttttgaa aatttttgca ccaatgactc tagaaatttc ggttgctgca
     2461 gacgtcattt ctttagaaat gttataacgc ttattatact tagtaaatag aactcctcgt
     2521 acttcaagct tgtcgttcgt atattctttt accgtttcaa tagtttcact taactttatt
     2581 agtcctttta atgagaaata cgcagcttca actggaatga taatttcatc agaaacagta
     2641 aatgcgttga ctgtaagcat tcctaaactt ggtggacaat caattataat ataatcatag
     2701 ttgtccttga ttggttgaag tactctttta agcctgtgtt cacttcctac ttgagtaaat
     2761 tccctctctg cagaagaaag ggctatgtcg gctggcaaaa catcaattcc tttatagtcc
     2821 agaatagcat ctgtaatgtc agcctcccct tttaatactt cataaattgt aggttggttt
     2881 gttccatcta tatcgaaacc tacattatct gtagcatttc cctgaggatc aatgtccact
     2941 aaaagtacat ttttaccgta aacaaatttc aaacatgctg ctaaattaac gctagtcgta
     3001 gttttagaaa ctccaccttt ttgattggct actgacaata ttcttgccat taaaatatcc
     3061 cccattcatc ttatattata atataattat atcataatat tgtgatattg caatatcgta
     3121 tatgcattat attgtaatat tgtgtgatta ttttgtttta aagatatata tcggttcgga
     3181 tataaagatt attcatatgt tattcgaaat taaaataatc actttttatt actttaaaat
     3241 tttttattaa tgataagaaa tatgttttgc gagcagcaac tagaataatt taaacattac
     3301 taaactgtct atattgttac taataattcc cttcttatag tgcattttct tagaaaaaaa
     3361 caatattacg atatcatgat attaagatat cgtaatatta tacaattgtg attgatatta
     3421 tatatgtttt tttatttttt tatcatgttt aatcttgaag gaatcatatt ctttttctaa
     3481 agacaggagc ttttcataaa catcagacat gtttaaacta gaggccaggc ttaaatcata
     3541 aacgaatgaa gcaggtaatg attttattct acgttgtcgg gttatccagc ttgcaaccgt
     3601 tccttgtggg taggcatata actcacaaaa ttgttctaca gtgattccta aattcttgat
     3661 aatgtaaaca ttgatcgggt gcgagtaaac aaatgtattg atagacatgg tgcgtaagcc
     3721 tactttcttt tattattgcg tttgcaataa tagtttaaca cacgcattat tctagtatct
     3781 actcctattt gtaaaaacaa aaaaggattc atagagataa ctctatagaa tccgtaaaat
     3841 accttatata tataacggga agatataaaa cctaaaatta tgataacctg ctgcagcttc
     3901 tacatagaaa gagaagcgct caacaccaac ctcatttatc aaacgttggc cataacccca
     3961 aatctcttct gatagctgat caaaggttat atactttagc tcatattgct ggataatgtt
     4021 cattctaatc gactccattt attatcctgg taaaattcga tatgacgtat ttcgtcgtag
     4081 tgaattttgt cttttccaac gtagatcccc agctcatcac tacctaagat cttgccaat
//
LOCUS       DARPZF010000111         4112 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.118, whole genome shotgun sequence.
ACCESSION   DARPZF010000111 DARPZF010000000
VERSION     DARPZF010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.118"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(39..281)
                     /locus_tag="SLE65_002785"
     CDS             complement(39..281)
                     /locus_tag="SLE65_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEI8450015.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(313..870)
                     /locus_tag="SLE65_002786"
     CDS             complement(313..870)
                     /locus_tag="SLE65_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEI8450016.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(883..1071)
                     /locus_tag="SLE65_002787"
     CDS             complement(883..1071)
                     /locus_tag="SLE65_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEI8450017.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(1084..1650)
                     /gene="amaP"
                     /locus_tag="SLE65_002788"
     CDS             complement(1084..1650)
                     /gene="amaP"
                     /locus_tag="SLE65_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEI8450018.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            2067..2240
                     /locus_tag="SLE65_002789"
     CDS             2067..2240
                     /locus_tag="SLE65_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450019.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            2880..3353
                     /locus_tag="SLE65_002790"
     CDS             2880..3353
                     /locus_tag="SLE65_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HEI8450020.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            3362..3589
                     /locus_tag="SLE65_002791"
     CDS             3362..3589
                     /locus_tag="SLE65_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8450021.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT         1234 a          740 c          617 g         1521 t
ORIGIN      
        1 ttgttcttca tttcaacata agtttttctt caatttgctt ataatttacg tgcaaagaat
       61 gaaacgacta atactaaaat gattgcaccg atcaatgatg gaatgatagc cattcctgca
      121 attgttggtc cccaagttcc tagtaaagct tgtccaattg ctgaacctac taaaccagca
      181 atgatgtttg cgatgatccc cattgatgat cctttattcg tgattgctcc tgcaattgct
      241 ccaatgatac cgccgacgat taatgcccaa ataaatccca ttttaaattc ctcctaactg
      301 acttcttact tcttattgta cacgtggttc gttattttct ttgacttttt gtgcaccttt
      361 gcctacagca gattttgctt tatctgtttg gcgtgaagca aattgtcctg tggattttgc
      421 tgcttctgtt actttgtctt gtactgtttc ttgatctttt tggtattctt cttgtgtttt
      481 gatgtctgca acattcacat tcacttcgat aacatctaaa tgtgtcatat tgtttacttc
      541 agtactgatc aattctttga tttggttgta aatatcttcg atgtctttac cgtattctac
      601 gatcacatct agatccacag ctacttgttt cttacctact tctgtattga tacctgctgt
      661 tacgttatct gtgttgacta atttttcagc catatttgag aaaaatccgc catctaatgt
      721 caatagacca tctacatctt tcaatgcata accgatgatt ttttggatga ctttgtcttc
      781 ataagtcaat tcaccattca tcatgcggtt ttctcctttt tcatttgcca aaactgatcc
      841 atttgttgta ttcatgtttt tgttttccat ctttgtttcc tcctatgatt taaaaaattg
      901 atcaactatt cctgactgtt tcaaataaaa accgattcct gcgccaattg ctgtcatgat
      961 tatgatcaac aatgtcttga aaaatccaat cgttaaccat aaaacagcta gcagtagtcc
     1021 aagaccccca aagataatag ggagcttgta tgctgaaaat agttctttca ttatttggcc
     1081 ctcctattcc actcgagagt gcttgtagtc tcttgtatct tcttgttctt cataaccgct
     1141 gtatgtgact gccactttga ccgtttcttt tgttccgagt actttagtta cttcttcttc
     1201 gatatcttgc atcaatacac ctgttttccc tactaatgaa gaagttcgtt tcaagtctcc
     1261 gttgacatgg atatggattc gatttttcgt tgaacgtatc cgtactttag gtgaatgaat
     1321 gaactcttct tcgtgtaaat gggaacgtac caacccttcg atcgcttttt tgtcgattgt
     1381 tagtttgcca tcttcccgtt tcataacgaa agttcctctt gactttggat agaaaagaac
     1441 gactagcaag atgataatag caagaacggc aaatactaca gctgcccaga aaatatattg
     1501 ttgcatgtag taattcgtta aagtaaagaa gcgaaatcgt tccaattgtt caggcataat
     1561 atacggcgca ttgatcaacg caatcgctag aaatactgaa agtagcagta aactcatgat
     1621 aacaccgatt atttttaacc ccttattcat tttccacctc ctataaactt atttttaccc
     1681 tgtaaataac tctaccgaca atcacagtat agatagcgaa cagttagcat agcatcagta
     1741 aataaagcgc taccaaacat tgctggatca taacggcgtt ttattgccag tctgatactg
     1801 aaataacaat tgcttactta ttctctattt acttttgatt gctggctata cttaaaggat
     1861 attattcaag attaaaaatt gcaaagatta tgctcagtta ttattacaag attctattta
     1921 tttattaaat tttttcggag aattaaaaaa tacaataaat aactttagtt actttaatgc
     1981 gttcttactt tatttttata ttatcatttt tcttattcac ttctttggtt tatactattc
     2041 ttataaataa aaacgaggta tgtcctatga tgaaaagatt gtactattca ttgatcataa
     2101 cgattggcta tttgattgta tcaaatctag gaaatatggt atttggtatc agtaaagaat
     2161 tcagttggac tactacatta tgggaatctc tattcttttt catcttcgta tttttgttac
     2221 aaaattatcg aaaaaaataa acatgtgcca tctatctgtt ggcacatgtt ttaggattta
     2281 tggtactttt tattcggcaa tccattttat ttttctactt cttcttaata cctctaacac
     2341 ttttgattta taaactaatc caatgcatct acttgcgctt attaagctat ttcagctaga
     2401 tagtaccacc ccatgcgtca atgcttgatt ttccttttgt ataacattgt ataagcaata
     2461 aaggacaaat aagtggtgat tacaccaaac cattgaataa gaaaaattct gatacgtaaa
     2521 taaacatgaa cttgaaaaaa ttaatgaatc ggttagctac tacgtagttg tcttttttct
     2581 catacagttc tgttaactta cacttctctt cgctagataa taaaaaatcc tccaactgta
     2641 ttgtccaata taatcccagg catctaaact agcattatag aagagacaca catagaatct
     2701 aaaataactg gttttaaatg tttcttacaa tcaaaaaaag ctgttaaatg cactccacac
     2761 cttcatactc tatcattttt tataaacgat atatttttat tgtttttcga taaaaaatag
     2821 ttgttttaca ataattattc tgctatattt tagctatcaa agataaaaga gggataaaaa
     2881 tgaaatttaa aacattgcta ttaaaatttg tcgttttagg tataagtgcc gtatttattt
     2941 tgttcggcgt acttttttat actcagatcg ctacaagcga aaaaggattc aattttgatt
     3001 ggcagaccac attatttgtt tctgtcattt actttgccct tctcctaggg atcgttattg
     3061 cttatttctt attgaaacta ttgaaaaaaa tcgaagataa ccaagctttt tccactcaaa
     3121 gcttaaacat actaaaaaaa atcgaacgaa ccattttgtt tattggtttc gccttttttg
     3181 gcttacttcc taaatttatg aaagtagcgg atttagacga tgctccaggt ttgatgttgg
     3241 taggaatcgc tgtcgtattc attccttttg cagtatacac attaacaagc gtgctggaaa
     3301 aactgcttga acatgcgatt ttacttaaga cagatcatga tttgacagtg tgaggtgcga
     3361 catggcaatt atcgttaatt tagatgtagt attagctcaa aaaaaaatga gtgtgactga
     3421 attgagtgag aaagtgggca ttacgatggc aaacatctct attctaaaaa atggaaaagc
     3481 aaaagccatc cgtttttcca ctctcgaaaa aatctgccaa gttttggagt gtcaaccagg
     3541 tgatttgttg acctataaaa atgactcgaa tactatacca gaagaataaa ataaagtaga
     3601 acaaacagta aataaaaaat aatctgaatg atagatgtgt gagactttta gaagttattt
     3661 acgtctatta ttcagatttt ttatttcgat tgaataccgt tttatctata aataagatat
     3721 gtactgactc atacaaaggg ggccttttct tctccatgta ctatcacttt tcctgataca
     3781 actggtttcc tgttacgttg tagttggatc tgcttttagt ataatacttt attcattcca
     3841 ccagactgat agcagtttga gcagtctaaa taatcatgta gtattacagg ccattctgtt
     3901 tcataccttg aagtgcttaa aacttcagct aatggcccat tgtgttaact cttactccat
     3961 tcttttttag taagctccca tatatactgt aaagccttct atatattatg tcatgttgct
     4021 ttttaacatt tactatgtag ttttgataaa atgatttgaa taacagtgat ggacaattct
     4081 tttttatttt taacattatt ttgataataa tg
//
LOCUS       DARPZF010000112         4074 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.119, whole genome shotgun sequence.
ACCESSION   DARPZF010000112 DARPZF010000000
VERSION     DARPZF010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4074
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.119"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(77..1051)
                     /locus_tag="SLE65_002792"
     CDS             complement(77..1051)
                     /locus_tag="SLE65_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEI8450022.1"
                     /translation="MSKKGTIINEWEKLTAPSNRRLSVPFMDTPLKIQWSIDRITIVG
                     NLKENIYYHTTHDVLILDFEQLMRLNEGNGYLRSVSNNGWQLLDQHEENIAYIEILKW
                     QEGKGRIDFNPNKISQFLASSMKNFIHDLFIEPHFSRADIACDIIDVPDEFITQYRVV
                     DPVSFKPIYGRNGKLETAYWGSRSSERQIRMYNKKLEQEKKRKIVPKEIVSWWRLELQ
                     LRRGKATDWHAMVYESLDSFASPHYLPADTSVADKMMITALTTEHDYWGQINRKTKYK
                     YRNLLKQESQNDELTNHLRETFAESADDLKKELDTWLLGLDVTEEEEK"
     gene            complement(1500..2915)
                     /locus_tag="SLE65_002793"
     CDS             complement(1500..2915)
                     /locus_tag="SLE65_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HEI8450023.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKTNDWHKHIDFTKSDEN
                     IYLEQTNLADKYEELFGEVVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     ILDDFQTNRADGSSTGISKQQAEQNRVIANKILVQYYKEFQERNPNLAVYNAVIHNDE
                     ISPHLHLNIVPVAEGYKRGVQKQPSFNKALVQQGIHADKDNGRVLFNNFRNQEVDSIE
                     RLMNDYGWKRDIVGTNKIKDIHEYKEIMSEISELRQTAVKERESISAEMRYISKQREK
                     NEREKALVASEKAKIEEEKKSIIDLEKELAVVFQKDPVPLNSFEKLSDGSYRLSSADF
                     VDLYQKASNATNSKKYADMANESLGNTLDKNIALFDKNMALEQENSFLKNQQKVDVSA
                     VVAENKKLKEENRSLRRRLTQLKNAFQKSITRLSIRFGLVEKDMGISEELKILDQEKT
                     LASQQNAPERNIGRSENEMEW"
     gene            complement(3137..3499)
                     /locus_tag="SLE65_002794"
     CDS             complement(3137..3499)
                     /locus_tag="SLE65_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450024.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAEMGKALRKH
                     FGFESFDDFERWLSSISDDQQHEKSVDNEWLADEKSAPSERDYPNESDGLLGVIPSKK
                     SQMSESKFTSMFNDVSLR"
     gene            complement(3503..3850)
                     /locus_tag="SLE65_002795"
     CDS             complement(3503..3850)
                     /locus_tag="SLE65_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450025.1"
                     /translation="MVAVLEMRCNMDKIDLREETVDRIELMYERLADYLNLPDEDNYS
                     EMLERMMDVLNSTINVGLANSSLITDKFVYGKIAETEDESEKEFWLNILTYVMQLNQI
                     GVIYRNKSKGKEL"
     gene            complement(3921..4061)
                     /locus_tag="SLE65_002796"
     CDS             complement(3921..4061)
                     /locus_tag="SLE65_002796"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450026.1"
                     /translation="MSGKLLDVTQYELILKNNKIDSPIIIPKHAVKYIYAVAESSGEA
                     ND"
BASE COUNT         1153 a          896 c          576 g         1449 t
ORIGIN      
        1 aaaaaaacaa ccacaacgta atcacctgtt aaatttacca accaattttt cttaccaaaa
       61 tacttttgtt tttctgtcat ttttcttcct cctctgttac gtctagccct agaagccatg
      121 tgtctaattc tttttttaaa tcgtctgccg attctgcaaa ggtttctcgt aaatgattcg
      181 tcaattcatc attttgactt tcttgcttca gcaaatttcg atatttatat tttgtctttc
      241 gattaatttg cccccaataa tcatgttctg ttgttaaagc agtaatcatc attttgtcag
      301 ctacacttgt atcagcaggc aagtaatgag gactagcaaa actatctaag ctttcataaa
      361 ccatagcatg ccaatcagtc gctttccctc gtcttaattg taattctaac cgccaccaac
      421 tcacgatttc ttttggcaca atttttcttt tcttctcttg ttccagtttt ttattataca
      481 tccgaatttg acgttcagaa gagcgagatc cccaatatgc cgtctctaat tttccattcc
      541 gtccataaat aggcttaaaa gaaactggat caactacccg atattgtgta ataaactcat
      601 caggtacatc gataatgtcg caagcaatat ctgcacgtga aaagtgaggt tcgataaaca
      661 aatcatgaat aaaatttttc atggaactag ctaagaattg actaatctta ttcggattga
      721 agtctatacg ccctttcccc tcttgccatt ttaaaatttc aatataagca atattctctt
      781 catgttggtc taacaactgc caaccattat tactaacaga tcttaaataa ccgttacctt
      841 catttaggcg cataagctgt tcaaaatcta aaatcaacac atcatgtgta gtgtgataat
      901 agatattctc tttaagattt ccaacaatgg taattcggtc gattgaccac tgaattttta
      961 ggggggtgtc cataaaaggg acacttaacc gcctgttaga gggggctgtt aatttttccc
     1021 actcatttat gatcgtgcct tttttactca aatttagttc ctcctcaaag aaaaaagaga
     1081 ttggtggaaa gaattttcca gagttcacgt aactctaaaa aattcataac cagcaatctc
     1141 tagtcttgaa gaaacctgaa attattcgta taatgaattt gagttacgga gctagtgtga
     1201 ttagtttccg taaaggtcga gaacgtgtcc agcgttgctc gactttattt ttttgctctt
     1261 ttttcagttt atttatttga taactcaata atagcacttc tctttagcta tgcaaatatc
     1321 caaaaacata aaaccgcacc ctttgaaaag ggcgccccca aacttcgcta acgctaagtt
     1381 ggccaaaaaa tggacttgcc attttttagc aaatgtcagc ttcagggatt agtggtttag
     1441 ccgtcaactc cttatcctcg gcacagaccg cctccggtac cgttgactgc accgtataac
     1501 taccactcca tctcattctc agaacgccct atattacgtt ctggggcatt ctgctgacta
     1561 gccaacgttt tctcttgatc taatattttt agctcttcag atattcccat atctttttct
     1621 acaagcccaa aacgaattga taaacgagtg attgattttt gaaatgcgtt tttcagttga
     1681 gttaaccgcc gacgcaaaga acgattttct tccttcagct ttttgttttc agcaacaacc
     1741 gctgacacat caaccttttg ttgatttttc aaaaaagaat tttcttgttc taacgccatg
     1801 tttttatcaa ataaagcgat atttttatct aatgtatttc caagcgattc attcgccata
     1861 tcagcatatt ttttgctgtt cgtagcatta gacgcttttt gatacaaatc tacaaaatca
     1921 gcactagata agcgataaga accatctgat aatttttcaa aactattgag tggcacagga
     1981 tctttttgaa atacaacagc cagctctttt tccaaatcga taatcgattt tttctcttct
     2041 tcaattttcg ccttctcaga agccaccaga gccttctcac gctcgttttt ttctctttgc
     2101 ttagaaatat acctcatttc cgcagaaatg ctctcacgct cttttacagc cgtttggcgc
     2161 aattcagaaa tttcactcat gatttctttg tattcgtgaa tatctttaat tttgttggta
     2221 ccgacaatat cccttttcca accgtaatca ttcattaatc gttctataga gtcaacttct
     2281 tgatttctaa aattattgaa aagcactcga ccattatctt tatcagcgtg tatcccttgt
     2341 tgaaccagtg ctttattaaa gctcggctgc ttttgaacac cccgtttata accttcagca
     2401 accggcacaa tattcaagtg caggtgcgga cttatttcgt cattatgaat aacagcatta
     2461 taaacagcca aattagggtt tctctcttga aactccttgt aatactgaac caaaatttta
     2521 ttggcaatca ctcgattttg ttcagcttgt tgtttcgata tgccagtaga agaaccatct
     2581 gctcgatttg tctggaaatc atctaaaatg cctatttgca caataaattc tcgttgaggt
     2641 tccaactttt tatccttgcg cactttcgct aaatagtcct cgatttttct atcggctctt
     2701 ttttgtttcg cattatattt ttctaccact tcgccaaaca attcctcata tttatctgct
     2761 agattcgtct gctctaaata aatattttca tccgatttcg tgaagtcaat atgcttatgc
     2821 caatcattgg ttttctggct atcagttaac tcacgattat tatgagaaat acttgtattc
     2881 ttcgttcctt ttttaaatga aatactaaac cccaagttaa aaccctcctt cgcgctgtcg
     2941 ctaataaaaa gagtgtaaac ctttctgtta ctctttgtca aagagtaaca ttttcctaat
     3001 tgtgacatgg ctgtcacaat tccaaatgct ctccgagggt attcgctgtc acaagtgaca
     3061 acgaaaaaag gagccgaaag cgtgtcacgc tctcaactcc ttttacgctt tattttgctt
     3121 cacgcaaaat aatcgcttat cgtaaactca cgtcattaaa cattgacgta aatttactct
     3181 cactcatctg acttttttta ctcggtatca ctccgagtaa gccgtcagat tcattgggat
     3241 aatctcgttc gcttggcgct gatttttcat cagcaagcca ctcattatcc actgattttt
     3301 cgtgttgctg atcgtcagaa attgacgata accaccgctc aaaatcatca aaagattcaa
     3361 atccaaaatg cttccgaagt gccttaccca tttcagcatt ttccttctca atcaatcgtt
     3421 ttttctgttg acgaagtttt gcctgttctt ttttcaattt ttcttcttgt gctttaatat
     3481 ctgctaaagt cattcccaag atttacagct ccttgccttt tgatttattt cgataaataa
     3541 caccaatttg atttaattgc ataacataag ttaaaatatt cagccaaaat tccttttcag
     3601 attcatcttc tgtttcggct attttaccgt aaacaaattt atcagtaatc aaagaagaat
     3661 ttgctaggcc tacattgatt gtagaattga gaacgtccat cattctctca agcatttcac
     3721 tataattatc ttcatccggc aaattcaaat aatcagctaa tcgttcatac atcaattcaa
     3781 ttctatcaac tgtctcttct cttaaatcaa ttttatccat gttacacctc atttccaaaa
     3841 ctgccaccat ttccgattct ttaattttcg atacacctaa ttcatcagca agatttttta
     3901 tggtcatctt ttctgacaaa tcagtcatta gcttctccac tactttcagc taccgcataa
     3961 atatatttaa cggcgtgctt agggataata atcggagagt caattttatt atttttcaaa
     4021 atcaattcat attgcgttac atcaagtaac ttaccggaca tttttttgct atcc
//
LOCUS       DARPZF010000113         3956 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.120, whole genome shotgun sequence.
ACCESSION   DARPZF010000113 DARPZF010000000
VERSION     DARPZF010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.120"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..156
                     /locus_tag="SLE65_002797"
     CDS             <1..156
                     /locus_tag="SLE65_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HEI8450027.1"
                     /translation="DKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDA
                     ISYGVRK"
     gene            175..1452
                     /locus_tag="SLE65_002798"
     CDS             175..1452
                     /locus_tag="SLE65_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8450028.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1462..2118
                     /locus_tag="SLE65_002799"
     CDS             1462..2118
                     /locus_tag="SLE65_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8450029.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2118..3494
                     /locus_tag="SLE65_002800"
     CDS             2118..3494
                     /locus_tag="SLE65_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8450030.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3624..>3956
                     /locus_tag="SLE65_002801"
     CDS             3624..>3956
                     /locus_tag="SLE65_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEI8450031.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1594 a          423 c          693 g         1246 t
ORIGIN      
        1 gataaggata agtgtattaa ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat
       61 tcagttgaga attgcaatca tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt
      121 ccagtggatg caattagtta tggagtaaga aaatagagag gagtagttag gaaagtgata
      181 aaaaatgcta tagcatatat tacaagaaag aaaaatagaa ctttaataat ttttatcata
      241 ttaactatag ttctttcttg cttgtattct tgtttaacaa taatgaaatc aagcaatgaa
      301 atagaaaagg ctttatatga aagttctaat tcttcaatat caataacaaa aaaagatggt
      361 aaatatttta atgttaatca atttaaagat attgaaaaat taaaagaaat tgaagaaaaa
      421 ataattcaat atgatggatt agcaaaatta aaagatgcta aagtagttag cggagaacaa
      481 agaataaata gagaagattt atctgacgaa tttaagaatg ttgtttcact cgaagctaca
      541 aataatacta aaagaaatat tttatttagt agtggagtat ttacaattaa agaaggtaaa
      601 aatatagaag aaaatgataa gaattcaatt attgttcatg aagaatttgc taaacaaaac
      661 aatctaaaat taggtgatga agttgatctt gaattactag atattgaaaa aagtggaaaa
      721 ataaaaagtc ataaatttaa aattataggg atcttttctg gtaaaaaaca ggaaacatat
      781 acaggattat cttctgattt tagtgaaaat atggtgtttg tagattattc aacaagccaa
      841 gagatattaa ataattcaga aaataatgaa attgcaaata aaattttaat gtattctggt
      901 agtgcagaat ctacagactt agccttaaac aaattgaaag agcttaaaat tgatgagtca
      961 aagtattttg ttgaaaaaga ttctaatgcg tttgaagagt ctttagagtc agtgagtgga
     1021 ataaaatata taataaaagt aatgacttat tctattatgt taggtgggat ggttgttctt
     1081 tcattaatct tgattctatg gttaagggaa agaatttatg aaataggtat attcttatct
     1141 attggaacat ctaagataca aattataatg caatttatat tcgagttaat attcatatcg
     1201 ataccaagta taatatcttc cttattttta ggaaatgtat tactaaaagt aattgtagat
     1261 ggattcatta actcagagga ttcaatgatt tccggtggaa gtttaataaa taatagtagt
     1321 tttatgtcaa atataacaac acttggacaa agttatttaa tattaataag tattattgtt
     1381 ttatcagttg tatttgcttc ttcattaatg ttaatcaaga agcctaaaga aatcttatca
     1441 aaaataagtt aggagaaaat aatggatata ttagaaataa agaatgtagc atatagttat
     1501 gcaaattcta aagaaaaagt tttgtcagga gtaaatcaaa aatttgaact tgggaagttt
     1561 tatgcgatag taggaaagtc aggaacagga aaatctacac ttctttcctt acttgctgga
     1621 cttgataaac ctcaaacagg aaaaatattg tttaagaatg aagatataca aaataaagga
     1681 tatagtaatc atagaaaaaa taatatatct ttagtatttc aaaactataa tttaatagat
     1741 tatttatcac caattgaaaa tattagatta gtaaataaat cagcagatga aagtatcttg
     1801 tttgaactag gtttagataa aaaacaaata aaaagaaatg ttatgaaatt atctggtgga
     1861 cagcaacaaa gagtagctat tgctagagca ttggtatcag atgctccaat aatactagct
     1921 gatgagccta ctggtaatct agacagtgtt actgctggag aaataattaa tatattaaag
     1981 acattagcta aagatagaaa taaatgtgta atagttgtaa cacatagtaa ggaagtagca
     2041 gattctgcgg atatcatttt agaactaagt ggtaaaaagt tgaaaaaagt aaataaaatg
     2101 aatttggagg ttgaataatg ataaaaaatg catttgctta tgtaactaga aaaagtttaa
     2161 aatcattaat tatcatatta gttattttat ctatgtcaac tttaagtctc attagtttat
     2221 ctattaaaga tgctacggac agagcttcaa aagaaacatt tgctaatata acaaatagtt
     2281 tttctatgga gataaataga caagtaaatc caggaacacc tagaggtggg ggaaatgtaa
     2341 aaggtgaaga tattaaaaag atatctcaaa cagatagtat agactcctat gtaaaaagaa
     2401 taaacagtgt tgcagattta gttgattatg atattattga aactcaagag actcttgcga
     2461 atcaatcacc tgaaagagca aagaatttta aaagaacagt tatgttaact ggggttaacg
     2521 actcaacaaa agaaacaaaa tttgtatcag aagcatataa attagtagaa ggaaagcatt
     2581 tagaaaatga agataaaaat aaaatcttaa tgcataaaga tttagctgaa aaaaataacc
     2641 ttaaagttgg agataagata aaaataaaat ctaatttatt tgatgctgat aatgagaaag
     2701 gtgcagatga aacagtagaa gtagaaatta aaggtctatt cgatgggcat aatagcggtg
     2761 tagtaagtgc agcacaagaa ctatacgaaa atacattaat cactgatatt catacagctg
     2821 ctaaagttta tggtaatacc gaagatacag ctgtatacca agatgcaaca ttctttgtaa
     2881 aaggtgataa gaatcttgat agtgtaataa aagatcttgg gaaattagat ataaattgga
     2941 gagaatataa tttgattaaa agttcatcaa attaccctgc attacaacaa tctatatcag
     3001 gtatttactc aatttcaaat aaattatttt ttggctcatt aatatttgca ggagttgtag
     3061 tttcattatt attattctta tggatgaatg ctagaaagaa agaaatagca gtattactat
     3121 cattaggtat atcaaaatta gaaatttttg gtcaattcct aattgagatg gtatttatat
     3181 caatccccgc attcgttggt tcctatttct tagctcaata tacagctgac aagcttggga
     3241 ataatatatt gaataaggtt actggtgata tagctaaaca aatagctaaa caatctgcat
     3301 ctagccaatt aggtggtggg gcagaagctg aaggatttaa caagacatta tcaagtttag
     3361 atatcaatgt attacctaaa ttcatgattt atgtagttat atttatgagt ttagtacttc
     3421 ttgtatcatt gattatttct tcattcaata tattaagaag gaatccaaaa gaattattaa
     3481 ttgacaataa ttaaaatttt cggtgctttt tagcaccaaa aatgagagtg taatataaac
     3541 cgtgtaagta accatcaatc ctaggcgggt ggttgcttca cggtttttat ttttctaaaa
     3601 taagatcaag aggtgattac acgatggcta gaaagaaaag aaatcctgat gctgagaagt
     3661 tagctgaatc cattttgaat acttatcaac ccgaatctgt agaggatatg caagatgttt
     3721 taaaagatgt gtttggtccc ttatttgaaa aaatgcttca aggagaattg aataaccatt
     3781 tagggtatga cgcccattct aaagagccaa agaaacatga caatcgacga aacggttatg
     3841 gcaataagac gcttaaaacg agctttggta aagtaaacat tgatgttccc agagaccggg
     3901 aggcttcttt tgaacctgag ttgattccta atagaaaacg agatgtctcc gacatc
//
LOCUS       DARPZF010000114         3930 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.121, whole genome shotgun sequence.
ACCESSION   DARPZF010000114 DARPZF010000000
VERSION     DARPZF010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.121"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            171..515
                     /locus_tag="SLE65_002802"
     CDS             171..515
                     /locus_tag="SLE65_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEI8450032.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            516..935
                     /locus_tag="SLE65_002803"
                     /pseudo
     CDS             516..935
                     /locus_tag="SLE65_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            complement(1027..1377)
                     /locus_tag="SLE65_002804"
     CDS             complement(1027..1377)
                     /locus_tag="SLE65_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450033.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1343..2674)
                     /locus_tag="SLE65_002805"
     CDS             complement(1343..2674)
                     /locus_tag="SLE65_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HEI8450034.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2930..3496
                     /locus_tag="SLE65_002806"
     CDS             2930..3496
                     /locus_tag="SLE65_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEI8450035.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3641..3728
                     /locus_tag="SLE65_002807"
     tRNA            3641..3728
                     /locus_tag="SLE65_002807"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3673..3675,aa:Ser,seq:cga)
BASE COUNT         1436 a          677 c          762 g         1055 t
ORIGIN      
        1 taaaaaaagc gttagcaact atgcttaaaa agcatatcga ctgaataaac taagcattgg
       61 acaggctgaa agactacatt taaaatgaaa tgcgaagaaa caatagaaaa taaagttgcc
      121 ttagaaccat agttgaatca cctaacagtc gtgaagggag aataagagaa atggcagaaa
      181 aacaaaccgc aggacgagat caattaggag attttgcacc aaaatttgca gaattgaatg
      241 atgatgtttt atttggacaa gtatggtcca gagaagaatt atctgctcat cagcgtagta
      301 tcatcaccat atctgcatta atttcaggag gaaattttga acaattgcca gctcatctga
      361 agattggcaa gcaaaatggc attactagtg aagaaatagc agaaatcatt acccatttag
      421 ctttttatgt aggatggcca aaagcttggt cagcttttag tttagcaaaa gaaatctatt
      481 tagaagaaaa tagcgaagat aagaaagagg cgtaaatgac gacaaaacac gaagaaatac
      541 acaatggcgt gatttttcca gcaggtgaaa aaaacgaagc ttacgctcaa gtatttaccg
      601 ggtaaagcta tctgaatatg ttagtgaatg atcccgaagt ttctgttggt gtaggtaatg
      661 taacttttga accaggttgt cgcaatcact ggcatgtcca taaagacggc tatcaaatct
      721 tacttgtgac cggaggagaa ggctggtatc aggaagaagg aaagccagca agacgattaa
      781 tggctggaga tgtcgtcgta acgcacaaag ggattaaaca ttggcatggt gcgacaaaag
      841 acagttggtt tgaacatttg gcgatcactg ctggtaattc agagttttta gaacctgtaa
      901 cagatgaagt gtatgaagga ttggaaaatc aataatgtca agcttgaaca gctcctgaaa
      961 gtagatttta atcgaacttt caggagctgc ttttttgatt cagtctttta taaatagaaa
     1021 atagggttaa taataggaat gagaagcacg tcgaaagatc ttaatattga taatcggctg
     1081 ggcatacatg atttccacgt catcaatcaa actacctaac agatgataat cttcccgatc
     1141 atgtcgggga ttacctaata gttcttgata atagatttcc atactagggt cccgaggatt
     1201 gttcagcaaa tcagcaagta catctaaatc ttctggctga gtttctgccg taccctgtat
     1261 ctctatgaaa agcccttcct cagcaaattc tactccaata cgtatttcag ttatttcatg
     1321 ggaatataaa taagtaagaa gctcatcgat gattcttttt gataattctt tttccaagtg
     1381 tctttttttc ctttctgaca gcggtaaagt tatctagtat cggtacaagg atacctgcaa
     1441 cgaaaccagt tgaaaaacca ctgttatata gatttagtcc tccgtgcaaa gtgctgacgt
     1501 tatggacaag agcaatatgt agtacaccag ctattacacc gtaaaaactg ccgtaaaaac
     1561 cgcttatggg cgcgagacct gtcccaaaca cagctgcaac aagcatgcca gtactggtga
     1621 tctcatgaaa agttccaaac aaagaagcaa taaatattcc gactagtatc ggaaaactgt
     1681 tttttaaatg acaaccaaaa gcactgaaac ccaccgcaga taaaatagca ccgatgacag
     1741 gtccatttaa ctgaccgcca accagcaaaa cataagaaga cagcatcaga ccaactaagc
     1801 ctatgttgat caaagtagca ccaataccag aattagcaat gaaatcagtt gtcaattttc
     1861 cagatgaatc gaaaatttct cgaatcccca aaagccgaaa ggaattataa tagaaaccaa
     1921 ttccgactgt cagcgaaaaa aagccaaaaa taatccaaat gagaggaaag tgatattcat
     1981 tgaaaaccaa tgtattttcg acgattgaat agctgaataa cctcaaaaca gcagtaaaag
     2041 tcatcgcaat caacccagag gtgaatccaa tattataaag tgtgaatcca cgatggaaaa
     2101 ctaaagtttg agcagctaag ggcggaagaa gtagaccaat tgctatgcca gctaaattcc
     2161 ccaataaaat acctatcagt aaaggaaaac gcataccaaa agtgatataa ctaacgaccg
     2221 gtgataatgc gctaccaaac agtccgatca tgatgtactg agaaaaaggt ttattgacaa
     2281 atacagcgta tagatacaca cctaaaatga ttgagataga attataaagg tttttgccaa
     2341 aaaaagagaa accggtaact gttagaatcg aagcaaataa gggaccgttt aaaatcacct
     2401 tgtgccgata agctaaaagc acagaaagta aggtcaaaat ccctacattt atgaatgcgc
     2461 ttccgaaacc gcctaaagca aaataatctg tcaaaagatt gcttggcgag gtaagaatag
     2521 ttagcaatcc actccaatta tcagtaggag tattagaaag caagccaata aaaagaaaaa
     2581 aaacacctgt aaaaccaaga taaaaatact ttcttttctg tgaaacgatt cgtttttgag
     2641 gatgaatata aataacgtca gtttcgtttt ccattacaca ccttcttttt cattttcttt
     2701 aactataact tgaaatgaaa gatttggaca actatcattt aggtcaaaac taaaaatgta
     2761 agggaaccca ttgaatttaa ccaaattttt ttaattttgc aaaaaaaagt taaagaagac
     2821 tgaaaaaaaa tttaaaatat aacgttttga gtaaaatgtt tgcaaaaaat gctaaaaata
     2881 gggtacaata aaacaacata tactgcagta aagaagtggg ggagttttaa tgagaagaaa
     2941 agtctatacc aaggatcaaa ttctaaaagc tgcttatgat gttgttgcaa aggaagggtt
     3001 taaaggattt actgcgagaa atattgctaa aaagatgggg atttcgacac agccgattta
     3061 tctggaattc aaaaacatgg aagatttaaa aaatacgttg ctggattcta tctttgaaca
     3121 actaaaagaa gatgttttcc ctattgaacg tactggtgat aaaatcattg atctcggttt
     3181 gaactatatc tactttgcaa aaaagcatca tagtctttac atggcattgt acattgatga
     3241 acatggggac ggaaagaaaa tgcatgattt ttcatacaat tatttccgtg aaatagttaa
     3301 agaagatgaa agatacaatc aattatcgga tgaatatgtc gatgctctgc atactggtac
     3361 atgggtagca gtgactggct tagcgtcatt gatgtcatca aacatcatgc atccaacaga
     3421 agaacaaatc attgcactga tcaaacggac aattgactcg attttagcat tagataatcc
     3481 tgaaataatc agatagtgtt ctatcagtat gaatttgatc ggtaagtccg ttggctgcaa
     3541 actgtcaatg gacttttttg ctaaaaaaag cgatttctgt tatttatcta ttagaaatag
     3601 gcttgacatt tcgtgaaaaa agtttaaaaa tagtacttac ggaaggttgg cagagtggta
     3661 atgcaccgga ctcgaaatcc ggcgaaccgg ctaataccgg cgcgcaggtt caaatcctgt
     3721 accttcctta tatcaacgat tagaggttgt gaagaagctg tcctgcatca agtaataaga
     3781 acggccaaac aaaaatagct tttcctattt tttcgtttga ttgggcttat taccgcagat
     3841 gcaagctttt gaacaccgtt tgttcggaat aaggggctgt gacaagactt ttgtcacagc
     3901 cccttattgt tgtactttta acctacaata
//
LOCUS       DARPZF010000115         3927 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.122, whole genome shotgun sequence.
ACCESSION   DARPZF010000115 DARPZF010000000
VERSION     DARPZF010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.122"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(89..1174)
                     /gene="xerS"
                     /locus_tag="SLE65_002808"
     CDS             complement(89..1174)
                     /gene="xerS"
                     /locus_tag="SLE65_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEI8450036.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3250..3768)
                     /locus_tag="SLE65_002809"
     CDS             complement(3250..3768)
                     /locus_tag="SLE65_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEI8450037.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1271 a          642 c          591 g         1423 t
ORIGIN      
        1 taaaaatgat aatgaagctt gcctttaaag ttgggctttt atctaatttt agagacaggc
       61 ttcattatta tactattttt tactacattt acaaagcgtt caaagcatca attgtagctg
      121 cattgtctat atgagtatat aaagttgttg tatttgtact tgtatgtccc aattgttggg
      181 cagttaatac caatgaattt gtctgttgat agagtctagt agccaaagta tgacgtaatt
      241 tatgtggact gacttggact ctgaatcctt ttgaatattt tgctaccatc cgttcgattg
      301 caataccgga tatacgcttg gcttctcctt gataaattgc tagaaataaa gctttttcgt
      361 tttctgttac tttgtatcgt tctttccgaa tagctagata attagctaaa tattccattg
      421 caaatgctgc tatatttact gcgtctctct tatttccttt tctagttact accacattat
      481 tcttttctaa agataggtcc tctaaattaa tatttacaac ctcggagagt cttaatccag
      541 atcctaaaat caatgcattg atcgccaggt ctctttctac atctcgttga taatagatca
      601 aagctcgttt gctcaaagtt tttttatatt cattggcaat ataatctaga taattttgtg
      661 tatcttcgtc tagaaataat tttttctcga ttgcgtttgc acgggcagct aacgtagttt
      721 tatctgtgat agttgctact tgatccatag gattattttc taagtatggt tttcctaaag
      781 gattattgga acttttcgaa agatatttaa atagaacctt taatgctgtg atatttctat
      841 tgatagtaga agtagataga cctaagttat tattatcttt gagcttagtt tttgttgtct
      901 ctttttttac attttccttt gtgcgacgtt tcaaatgaga tttgtacaag tttagatcat
      961 aggcagttaa ctgtcttatc gaggtgattg aagtatcggg aacgatagac tcactcagaa
     1021 gccattcata aaagagctta taatttttta gatattctaa agtagttcga ggtgattgat
     1081 ctttatcctc acgatcttga acaaaatctt ttatataatc gggcatatga agtatgattg
     1141 tatctatttt ttgatatatt tctgtatttt tcatgttatt catcctttcg ataagtaggg
     1201 gagaggagta tctctataat tggactatac caattataga gtgttttgtc aattggtata
     1261 ctctgaaatt tattaattta tttcaaaaaa gcagataaat aggtatagat ttaataattt
     1321 aaaataaatg gtatacatga ataggaaagg aaacagaagg aggcaatctt aattttttaa
     1381 attgtctaaa ttatatagaa agaacaatct ttctatataa ttagacataa gagagactac
     1441 ggttgatttg atattaacaa gcgtatatga atgtatatac aaataaaaaa ggggagggag
     1501 aagttaaaga aaattcagag aagtggggca ctcagtagta ttaacaattt aaaaggaatt
     1561 tcttaaagaa aatgggttgc atcctggaga tacaattttt ttagataaag aaaaaattca
     1621 agcaacaatt caaaaaaatc ttaactgctg agattgatgt agcaatatct caatcatcaa
     1681 caaagtacga tcctgccttt caaaagctta ttgataaatg tttattcatt ataaaaataa
     1741 aagaaaaatt tatgtcagct tttttcatca aagtggtaat gataattcgt ctattaattg
     1801 tattttttag gaaatatggt ataattgttt taacgaaaag gtaattcatg atacaccaaa
     1861 aaccactagc tggcgggcta gtggttttct tttacgttct attcagatta acgggtaggc
     1921 ttactgtctt ttttggcaat aattttgcaa tcaagccatt tacagatgta atgcgcggat
     1981 acttctgcta agattgcaaa aaacatatcg aaaaggtaat tcataataca acctcctccc
     2041 cttgccataa taggccgggg tagcagacag cataaatatt ataccataac tgaaaatttc
     2101 attttagtac atttcaatat attgatgaac cagcacaata aaacatgcca tgactaacag
     2161 aaaaaaactt attaaaccag atataacttg taaacatcca actatataga aaacgtaaat
     2221 tttctatata gttggattaa gataacgact atttatttta tcatattttt actataccct
     2281 atacttttac ttggtatatt tatgaataat cgcaaattta cccctatact actagtttgt
     2341 aagttagatt aataaaaata ctaaagttat ttgttctttt attaaataca cctacaactt
     2401 ataaattgat ggtatttaga taacacgaaa gaataaaaat aacagctgat agtaaagttt
     2461 gttgacgatt gctactcaat cgaaagtgag ttagtgcgta tgaacttgct tctgaaaact
     2521 tatgaaatga aagacctttt acatcttgca gaaatcggta ctgggattaa actaagcaat
     2581 aaaaactaat gttcccctca ttctttgaac ttctactatt tgatttattt attctgataa
     2641 atgacgattt caccttcagg atcttcaaat cccgtataga atttatttaa gatctcttca
     2701 gtatcagtaa taggataggc gataggccac ataccctttg atggttagaa taaactgctc
     2761 aaaatctgta tcgtatgttg gctttagcat attaacaaag gctatctcca aattataaac
     2821 cataagcgtt gaatcgttct taacaatttc aattcttcct aacccaaagt cagaagatat
     2881 aattaccgga cttgccttac ccttcatgtg ggttgttgag attccatatt taaagggaat
     2941 tgtcggtact atcggcggtc tgaaaaacat cccaaaaata aaaaaatctt tcccctgcta
     3001 gtctcctaag tccctttgta gcggatatgg caccataatc tcattttatc gaagtgagtc
     3061 atggtttatc tgttggccaa ccaaaattga tacaatctaa cgatgcaccc tctacggcat
     3121 tctaggggag tgcacttgca ttcacccaat aaaaaccggc agttagcaaa gaacttatgt
     3181 agtcgtatgt tcttactgtt aacatacaag aggtctcctt tccacaattg cttagcagta
     3241 aacgggaatt tacaaagcta atctcttcca ttttcttatc tttgttctaa aagtcccaaa
     3301 tggagcaact gtatttacat gaataaattt atatacttcc catacagccg ttttggttgc
     3361 ctcgtctgcc cattttcttt tgtgtgcagt gaatagatct tcatcactca ttgaatcaat
     3421 catcatgtta atatcatcaa tattacgatt gagaatttcc tctaattctt tcaatggtag
     3481 atgtgcatag gtatttgtaa accacttata taactctcct aactgattcc atttaaattg
     3541 atcagaaggc gttttaacag ataatccatt tctttcatca ttttcccatt ttagaattaa
     3601 attcgtccaa ccaacttgat atgctaaatt ttcagcaggt gttctatcca cttcctcaac
     3661 tcttttatcc ttcaattctt caggaatagt ttcaaattct aaaatatatt tagtataagt
     3721 cctatttatt tcttttttta attcttcttt atttttatat gttctcatta tattacctcc
     3781 ataaattcct aattgtctcc tttaattcat ctataatttc atccacgata ttttaatccg
     3841 ttctacaatg catatctgat atgcattgac tgtctaactc atatgtgaat gatttataaa
     3901 atatcccaac gtctcatcta aagaaat
//
LOCUS       DARPZF010000116         3914 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.123, whole genome shotgun sequence.
ACCESSION   DARPZF010000116 DARPZF010000000
VERSION     DARPZF010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.123"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..114)
                     /locus_tag="SLE65_002810"
     CDS             complement(<1..114)
                     /locus_tag="SLE65_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HEI8450038.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDR"
     gene            184..564
                     /locus_tag="SLE65_002811"
                     /pseudo
     CDS             184..564
                     /locus_tag="SLE65_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            659..1210
                     /locus_tag="SLE65_002812"
     CDS             659..1210
                     /locus_tag="SLE65_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HEI8450039.1"
                     /translation="MKRLEASTSNFNNKLDVFEEKTKHARLNFETTAKHYIKRLDEDN
                     LKLDFQQAIQDELSDTKDEIREVTKQAREETKEYKEILESKIKDHNKVVDKSNTALKV
                     MTKGVTNIFFVLIIFVLVMLVTGPIGHFFGIEHLYSFINGFIDDHESAWRYLMLILYA
                     VPYVFFAIILWLIALFFRVFNDL"
     gene            1886..2140
                     /locus_tag="SLE65_002813"
                     /pseudo
     CDS             1886..2140
                     /locus_tag="SLE65_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            2210..2722
                     /locus_tag="SLE65_002814"
     CDS             2210..2722
                     /locus_tag="SLE65_002814"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8450040.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLC
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            2719..3756
                     /locus_tag="SLE65_002815"
     CDS             2719..3756
                     /locus_tag="SLE65_002815"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEI8450041.1"
                     /translation="MISSSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
BASE COUNT         1420 a          676 c          764 g         1054 t
ORIGIN      
        1 acgatcatat aacaattcct gaacttcacg atagcttaga ttgtaacgca ggtagtaacc
       61 aacagcgaca ataatgacgt cttttttgaa ttgtttgcct ttaaaatgat tcattactct
      121 gtcctctctg tcttttttct caattttaca ctaaaataga ttttttggaa aactttgcaa
      181 cagaaccttt ggttacgtaa aaaacgggac acacaagcag cctatgcttt tcttaagcgg
      241 ttagtgaagc agtttgatga accgaaggtt gtagtcacag ataaagcccc ctctattaca
      301 agtgccttta agaaactaaa agaatacggc ttttatcaag ggacagaaca tcgtaccatt
      361 aaatacctga ataatttgat tgaacaagac catcgtccag taaagagacg caataaattc
      421 tatcgaagtt tacgcactgc ctctaccacg attaaaggca tggaagccat tcgaggatta
      481 tataagaaaa cccggaaaga aggcactctc ttcgggtttt cggtctgtac tgaaatcaag
      541 gtattattgg gaatcccagc ttaaatcata gataccgtaa gggattttat tctttattta
      601 aaactttgca acagaaccga agagcgagca agacaggaac gagagaacaa acatactcat
      661 gaaaagacta gaggcttcga cctcgaactt taataataag ttagatgttt ttgaagaaaa
      721 gactaagcat gcaagattaa actttgaaac aactgcaaag cactatatta aacgacttga
      781 tgaagataat ttgaaattag attttcaaca agctattcaa gatgaattaa gcgatactaa
      841 agacgaaata cgtgaagtga cgaaacaagc gagagaagaa acaaaagagt ataaagaaat
      901 cttagaaagt aaaataaaag accataacaa agtggttgat aaatcgaata cagcgctaaa
      961 agtgatgaca aaaggcgtta caaatatatt ttttgtgcta attatttttg tacttgtaat
     1021 gcttgtgaca ggtccgatag gtcatttctt tggtattgaa catttatata gctttattaa
     1081 tggttttatt gatgaccacg aaagtgcatg gcgatatttg atgttgatac tttatgcagt
     1141 accctatgta ttcttcgcta tcattctgtg gctcatagca ttgtttttta gagtatttaa
     1201 tgacctttag gtagatttat atataaaaag ggctaaatac gcaaaatacc cccttaaaat
     1261 gcaaaataaa tgcaaataag ggggtaactc cttatgaaaa aacaactaat agtattataa
     1321 cacgttttta tgccgagaaa acttattggt tggaatgggc tatgtgttag ctaacttgtt
     1381 agcgagttgg ttggacttga attgggatta atcccaagaa agtaccaact caacaacaca
     1441 taaagccctg taggttccga ccaataagga aattggaata aagcaacgaa aggagttgag
     1501 taaaatgagt gagaaaacga agaaaatcat tcgagtatca ttagcttttt cacaagtagt
     1561 agtgcaatca ttgatagttt attatactta ccagcaatat aaattatcta aagagaatta
     1621 agttttgatt atgtaataag ttttggtact aaaaaagact tgatctaatt agaccaagtc
     1681 ttttgttagt gttatattaa taacaaaata aaaataagaa gtcgctcact ccccgaccaa
     1741 agtttgtgag caaaataaac agtcgatgtt tgtttcttaa ttgtatatct tgatattaaa
     1801 cgatttaaga ttattcttca agatatatat tcgcaaatgt aattggaaaa gcgacttctt
     1861 aaacaaaatt aaggagtcgc tttttatggc aaaaataacg aaaaatgagc aagaaaattt
     1921 ggtggaaaat tacacaaaaa aaccggcgta ctctaatagc cggttagacg cacatttcgt
     1981 gtgcacttct aatccgaaat tgagctttga cgctatgacg atagtcggaa accttaataa
     2041 aaacagcgct aaaaagctat ccgattttat gagtttagat ccacaaatta gactttggga
     2101 tatacttcaa acaaaattta aagctaaagc actacaagac cccctatgtt aggctagttg
     2161 tcgtatagga taataagtta taataaagac tatacggagg atgattacca tgacaaataa
     2221 aaacaatgaa cgttactcta ccgaactgaa agcgacagcc atcaagaaaa tgatgccacc
     2281 cgaaaatagg gggattcgcc aattaagtca aactttgggc attccagaag cgactctttg
     2341 ttcttggcgt aaaaaagcta gaattcaagg gaatactaca cccggaacga aaaaaaatgt
     2401 cgaaaaatgg tcaagtgaag ataaattttt aattgtgatg gaatcattct caatgaacca
     2461 agtagaactt gcggaatatt gccgaaagaa gggcttattt aaagaacaaa ttgaggcttg
     2521 gaagaaaacg tgcttatctg cgaatgaaca ggaagaaaat cgaacgagag aacttgcaac
     2581 tgaactaaaa gaagagaaaa aacaagcgcg tcaattagag aaagaattac gtcataagga
     2641 aaaagcatta gcggaagccg ctgctctctt attactaaga aaaaaagcac acgcgatttg
     2701 gggggaccaa gaggaagaat gatttcatct tcagatcgca aacaagctgt tgaacttatt
     2761 caagaagcca atcgcaatgg ggcccgtctc acctatgcct gtaatgagct gaatattagc
     2821 gttcgaacct acgaacgatg gacgcgtgaa ggtacgatag cgcatgatca acgccctttg
     2881 gcgaaacgtc ctgtacccaa aaataaactg acggatcaag aacgcgaaaa aataatagaa
     2941 accgtttcaa aaaaagaatt tatgaatttg ccacctagcc aaattgtacc aaaacttgcg
     3001 gattgctcga tttatattgc atcagagtct agcttctatc gtgtattgcg agaaaaaaat
     3061 atgcaacatc accgtggccg aagtcaagtt tcacaaaaac gcataccgcc aagtcacctt
     3121 gcgacgaagc caaatgaagt ttggacttgg gatattactt ggctaaaagg tccaataaaa
     3181 ggactctttt accggttata tctcatcatt gatttattta gccgtaaaat ggtaggctgg
     3241 gagatttggg aatcagaaga agctcgtcat gccgaaaaac ttattaaaca gacggtgctt
     3301 aaggaacgta tccaaggaca gccgttggtt ttacactccg ataatggcag ccctatgaaa
     3361 gccgcgactt ttcaagtctt actcgaaaaa ttaggaattc aaagttctta ttcaagacca
     3421 cgagtgagta atgacaatcc ttattcggaa gcggctttcc gaacgttaaa atatcgacca
     3481 gaatatccca ataacggctt taaaacaata gatgatgctc gaaaatggac gaaagagttt
     3541 gtcgattggt ataacgattc tcatttgcat agtgggattc aatttgtgtc tcctgcagcg
     3601 tgtcatgaag gacgacatct cgctatttta gagaaacgaa agcaggttta cgaggacgct
     3661 aaaaagcgcc atcctgaacg ctggtcaaaa ggtgttcgaa attggactcc acatcaatcg
     3721 gtggcgttga atcctttaaa agaaacagaa agttaacagg agcataatct ttcaagatta
     3781 tcaaataacc ctcgtcaccc aataggggaa aaagttattc ttcccctatt ggataacgag
     3841 gccaaccgac catagggagg ttctgctttt tgataggtgg aaaataaaaa tacgacaact
     3901 atattgacaa acac
//
LOCUS       DARPZF010000117         3735 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.124, whole genome shotgun sequence.
ACCESSION   DARPZF010000117 DARPZF010000000
VERSION     DARPZF010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.124"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            11..478
                     /locus_tag="SLE65_002816"
     CDS             11..478
                     /locus_tag="SLE65_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450042.1"
                     /translation="MIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIVSVI
                     MIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAFYYT
                     LKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
     gene            683..2347
                     /gene="alsS"
                     /locus_tag="SLE65_002817"
     CDS             683..2347
                     /gene="alsS"
                     /locus_tag="SLE65_002817"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HEI8450043.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            2360..3070
                     /gene="budA"
                     /locus_tag="SLE65_002818"
     CDS             2360..3070
                     /gene="budA"
                     /locus_tag="SLE65_002818"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEI8450044.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            3200..3697
                     /locus_tag="SLE65_002819"
     CDS             3200..3697
                     /locus_tag="SLE65_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEI8450045.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
BASE COUNT         1230 a          596 c          807 g         1102 t
ORIGIN      
        1 ttgcatcgtg atgataggta tgacagaaga attagcaaaa gaaaaaagtt tttcaccagt
       61 acgtttgttc ataaagacgt ttcgccaatt ttggctaaag ggattttttt attggctatt
      121 tgcttggata gttagtgtga taatgatttt tgattgtttc ttttttatac gtttttctta
      181 tggaaaatgg ttgattccgt tgtttgtttt acttgcttgt ttatcagttt cctttagcat
      241 caactactgg tattttcagg tgagaaatcc agcgtcgaaa ccaaatcaag ttctacggat
      301 agcgttctac tatacgttga aaaaatggta tgtgagttta ctagattttt tactattgac
      361 aagtttgttt ctcttctttt tcgtaaagcc ccaatggtgt attctactag gtccttctat
      421 cgtatttggt ttgatttact tcaacaatcg taaattgatg agaactatgg atctgtagac
      481 tttataaatt gaaactttca attaagaatg acagttttta tgtaaaaact gtcattcttt
      541 ttcatttttt gaaacatatg gctaaacaaa tgaaataaaa cgtgctatac ttttgaatga
      601 aacaggttta gaaactgtat caattatttg tgattatttc taactaataa ttaaaaataa
      661 agcataaaaa ggacgatgtt caatggacga aaaaatgaaa caaggttcga aatctgtagt
      721 agaaagtttg attaatcatc atgttgatta tgtattcggt ataccaggtg caaaaatcga
      781 tggtgtattt aatgaattag aggatcaagg tcctgaatta atcgtgactc gtcacgaaca
      841 aaatgctgca tttatggcac aagcaatcgg acgtattaca ggagagccag gagtagttat
      901 cgcaacaagt ggtcctggtg ctagtaactt agctacaggt ttggtaacag cgacagcaga
      961 aggtgaccca gttttagcaa ttgccggaca agtaaaacga agcgatctat tgaagttgac
     1021 ccatcaaagc atggataatg cagcactgtt ccagccaatc acaaaataca gtgcagaaat
     1081 ccaagatcca gaaacaattt cagaagtgat tgccaatgct tatcgtatgg ctaagagttc
     1141 aaaaaaaggc gcgagcttta tcagtatccc gcaagatgta gtggatgcac ctgtccaagg
     1201 gaatgtcatc aagccattga gcgatcctaa attaggttct gcttctgcag atgatatccg
     1261 ttacctagct gaacgcatta gagaagcaaa actaccggta ctattagtag gtatgcgagg
     1321 atcaagtgaa aaagaaacgt tagccatcag gcaattagtt ggaaagacag cattgcctgt
     1381 tgtagagaca ttccaagcag ctggagtgat ctcacgtgaa ttagaagcgc atttctttgg
     1441 tcgtgtgggt ttatttagaa accaaccagg agatatgctt ttgaaacgaa gtgatctagt
     1501 tattgctatt ggctatgatc caatcgaata tgaagcaaga aactggaatg cggaaaaaga
     1561 tgcgcggatc attgtgatcg atgaagcgcc agctgaaatc gatcctttta tgcagcctga
     1621 aagagaattg atcggtgata tctcagccac tcttgattta ttgacaggtt cattagagcc
     1681 tcaacaagtg tcagaagatg caaaagaata tttagcatct cttcaagcag aattaacgga
     1741 gcgggacatt gttcaatcaa aaggagaagc aggtatcttg catcctttag aagttattaa
     1801 cacgcttcag tcaaaagtaa cagatgatat gactgttacc gtagatgtag gtagtcatta
     1861 tatttggatg gcacgccact ttagaagtta tgaacctcgt catttgttat tcagtaatgg
     1921 tatgcaaacg cttggtgttg cattgccatg ggcgatttct gctgcattgg tgcgtccaaa
     1981 tacacaaatc gtatcagttt ccggcgatgg gggattttta ttctctgccc aggatttaga
     2041 aacggcggta cgtaaaaaat tgaatatcgt tcatttgatt tggaatgatg gacactacaa
     2101 tatggtagag ttccaagaaa aaatgaaata tcagcgggcg tcaggtgtag actttggtcc
     2161 agttgatttt gtgaaatatg cagaagcttt tggcgctaaa ggaatccgag ctacaagtgt
     2221 agaggaatta gaaaaagctt tagaagaagg atttgcgaca gaaggacccg taattattga
     2281 tattccgatt gattaccgtg ataatgagaa attgggagaa acaatcttac cagatcaatt
     2341 ctattaagga agtgtcgaca tgactgaaaa aatcttatac cagcacggga cattaggagc
     2401 tttgatggct ggcttgatgg atggaacaga aacgattgct catatattag aaaaaggaac
     2461 tctgggattg ggaacattgc atgggcttga tggtgaagtc atctttttag atggcgtagc
     2521 ttatcaagga agatcagatg gctcagttgc ccaattagat ggaagtgaac ttacccccta
     2581 tgcagcaatt acagatttta cgccagatac tagtttttct gtctcaaaaa ctgcagatgg
     2641 agaacaattg aaaaaagaca tattagtaag agaagccggg gaaaacctat ttttggcagt
     2701 gaagataact ggattattca aaaatatgca catccgtatc atgccgaagc aagaaaaacc
     2761 ttacagaaga ctagcaaaaa tttcagagtc tcaaccagaa ttccaacaaa gcaatgtcca
     2821 aggaacatta gtcgggttct ttacgcctga attattccaa ggagttgctg cagcgggatt
     2881 tcacttgcat tttatcgatg atacacatac atttggcgga catgtaatgg attttgaagt
     2941 ggctgaagga aaagttgaga ttagccgcat ctcgtccctt gtacagcatt ttccagttga
     3001 tgatccgact tttgttcacg aaacgattga ttatgctgat ttagcagcag aaatccaaca
     3061 agcagaatag aaaaagacag cgagatgcgt tcaaggtgat taacctgacg tatctcgttt
     3121 ttttgaggag gaaacctagc gtttacaaaa aaactgagct ataatcttct ccatagatca
     3181 aaaaggagcg gtttttatca tgtggacaga aaaacagaaa aaagatgcat acgaaatttt
     3241 attattacag caacaaggat tattagaagc agaagataac tggttagcaa atttagcaaa
     3301 ttcatctgca ttgttgaatg agactttgcc tgagactgtc tttgcaggat attatttatt
     3361 cgatggtaat gaattgattt taggaccgtt ccaagggcga gtttcttgca cacgtatcaa
     3421 gatgggaaaa ggagtttgtg gagaatcagc tgaaaaacaa gaaacattga tcgttgatga
     3481 tgtcaaaacc catgcaaatt acatttcctg cgattcagcc gcacaatcag aaatcgtagt
     3541 gccaatggta aaagaaggta atttaatcgg tgttttagat atcgattgcg gagtaacgaa
     3601 agggtatgat gaaatcgatc aagcatttct agaaaaatat gtagatcttt tattagcaaa
     3661 ttttaatata aatgcttttt catttattaa taactaaaat cgtctattga aacaaaaaag
     3721 aagagaaatc aagaa
//
LOCUS       DARPZF010000118         3655 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.125, whole genome shotgun sequence.
ACCESSION   DARPZF010000118 DARPZF010000000
VERSION     DARPZF010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3655
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.125"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            116..976
                     /locus_tag="SLE65_002820"
     CDS             116..976
                     /locus_tag="SLE65_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HEI8450046.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQEIKNYQIKNKLICHCSGAISS
                     DIFSNIQDYGAYGYSVHPMFSISDKYNSYKKLKKSFITIEGDEKYAKFLCDFFKKLGN
                     STVIVSKENKSLYHAASVVSSNLVLGLINTSVTYLIQCGFTEKMAIEALYPLIEFNIR
                     NIKEKGIIESLTGPVERCDISTIKGHCEVLSDEDRALYMLLSKNVLEIAMLKNINRDY
                     SELEKYLGES"
     gene            988..1815
                     /gene="panB"
                     /locus_tag="SLE65_002821"
     CDS             988..1815
                     /gene="panB"
                     /locus_tag="SLE65_002821"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HEI8450047.1"
                     /translation="MKNTAVTFKESKLRNEKLTMLTAYDYSTAKIIDEAGINGILVGD
                     SLGMVCLGHEDTLSVTMEDMIHHTRAVTRGAKNTLVVADMPFMSYQTSVYDSVVNAGR
                     LIKEGRAQVVKLEGGIEVCDKIEAIVKASIPVMAHIGLTPQSVNAFGGFKVQGKDKEA
                     AKELIRAAKAVEKAGAFAVVLECVPTKLAELISKEISIPTIGIGAGAGCDGQILVYQD
                     MLGMYSDFTPKFVKKYANLSEEMNKAFTKYIEEVKDGVFPGPEHGFKISDDVLEKLY"
     gene            1830..2678
                     /locus_tag="SLE65_002822"
     CDS             1830..2678
                     /locus_tag="SLE65_002822"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HEI8450048.1"
                     /translation="MVIFKTVNDVRSQVKEWKKQGLKVGLVPTMGYLHEGHESLIRKA
                     SKENDKVVVSIFVNPTQFGKNEDLGSYPRDLERDIEVCTRGRATAIFNPEVEEMYCDN
                     ASTFVNITGLTEGLCGASRPIHFRGVCTVVSKLFNIIPADRAYFGEKDAQQLAVIKRM
                     VRDLNIDIDVVGCPIIREEDGLAKSSRNTYLSLEERSSATILNKSLTLAKEALNNGER
                     DSLKIIEIISKNINTYNLAKIDYVEVVDSLSLQRVNYIEKSVLVAIAVFIGKTRLIDN
                     FTFELQ"
     gene            2688..3083
                     /locus_tag="SLE65_002823"
     CDS             2688..3083
                     /locus_tag="SLE65_002823"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HEI8450049.1"
                     /translation="MKVTMLKGKIHRATVEQAELDYVGSITVDMNLLEAAGIYEYEKV
                     QIVDVNNGNRFETYTIAGERGTGMICLNGAAARCVSTGDKIILMAYCELNENEVKDHR
                     PKVVFVDDNNKVERVTSYEKHGRLSDIIL"
     gene            3285..3655
                     /locus_tag="SLE65_002824"
                     /pseudo
     CDS             3285..3655
                     /locus_tag="SLE65_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1425 a          412 c          722 g         1096 t
ORIGIN      
        1 gatattatga taaattaact atggatgata tttgaaaaaa acatactgta tatttgattt
       61 aatttttatt tttaagctca tatcgtaaga atgggacttg tagtctcact tctttatgga
      121 ggtgataatt atgaacgttg gttttattgg agccggcaag gtaggttgtt cattcgggaa
      181 gtatttccag gaacataaaa tacaagtaac aggattttat agtaaaagcg aagactcgtc
      241 attagcagct tcgaatttta catctagtaa acaatattta aacttaagag aattagtaga
      301 tgaaaatgat actattttca ttacgactcc tgatggtcaa attcaggagg tatggcaaga
      361 aattaaaaat tatcaaatca aaaacaaatt aatctgccat tgcagtggtg caatatcttc
      421 agatatcttt tcaaatatac aggactatgg tgcttatggc tattctgtcc atcctatgtt
      481 ttcaatatca gataaatata attcatacaa aaaattaaaa aaatctttta taacaattga
      541 aggcgatgaa aaatatgcaa agtttttatg tgatttcttc aaaaagttag gtaatagtac
      601 tgtaattgta tctaaggaga ataaatctct ttatcatgcc gcatcagtag tatctagtaa
      661 ccttgtgcta ggacttatta atacaagcgt tacatatcta attcaatgtg gatttactga
      721 aaaaatggca attgaagctt tatatccatt aattgaattt aatattagaa atataaaaga
      781 aaaaggaatt atagaaagtt tgacagggcc agttgaacgt tgtgatattt caacaattaa
      841 aggtcactgt gaagttttat cagatgaaga cagagcttta tatatgctat tatcaaaaaa
      901 tgtattagag atagctatgt taaaaaatat taatagagat tatagtgaat tagaaaagta
      961 tttaggagag agttaggaga gaaatagatg aaaaatacag cagttacatt taaagaatct
     1021 aaattaagaa atgaaaaatt aacaatgctt acagcttatg actattcaac agcaaaaata
     1081 attgatgaag ctgggataaa tggaatatta gtaggagatt ctcttggtat ggtatgtcta
     1141 ggacatgaag atacactttc agtaacaatg gaagacatga ttcatcatac tagagcagtt
     1201 acaagaggag ctaagaacac tttagttgtt gcagatatgc catttatgtc ttatcaaact
     1261 tcagtatatg attcagtagt taatgcagga agattaataa aagaaggacg agctcaggtt
     1321 gttaaattag aaggagggat agaagtatgc gataaaatag aggctatagt aaaggcttct
     1381 atacctgtta tggcgcatat aggtttaaca cctcaatctg ttaatgcatt tggaggattt
     1441 aaggtacaag gaaaggacaa ggaagctgct aaagaattaa taagagctgc taaagctgta
     1501 gaaaaagcag gagcattcgc tgtagtgtta gaatgtgttc caactaagct tgcagagtta
     1561 atttctaaag agatatcaat acctacaatt ggtattggag caggtgcagg gtgtgatgga
     1621 caaattcttg tatatcaaga tatgttgggg atgtatagtg attttacccc taaatttgtg
     1681 aagaaatatg ctaatttatc agaagagatg aataaagcat ttacaaaata tatagaggaa
     1741 gtaaaagatg gagtttttcc aggtccagaa catgggttta aaataagtga tgatgtttta
     1801 gaaaaattat attaaaaggg tcaagaaata tggttatatt taaaacagtg aatgatgtta
     1861 gaagtcaagt aaaagagtgg aaaaaacaag gcttaaaggt aggattagtt cctactatgg
     1921 gatatttaca tgaaggtcat gaaagtttaa ttagaaaagc atcaaaagaa aatgataaag
     1981 ttgttgtaag tatctttgta aatccaactc agtttgggaa aaatgaagat ttaggtagtt
     2041 atccaagaga cttagaaaga gatatagaag tatgcacaag aggtagagca acagcaatat
     2101 ttaatcctga agttgaagag atgtattgtg acaatgcaag tacttttgtt aatataactg
     2161 gattaacaga aggtttatgt ggagctagta ggccaataca ttttagaggg gtttgcactg
     2221 ttgtaagtaa attatttaac ataataccag cagatagagc ttattttgga gaaaaggatg
     2281 cacaacagtt agctgtaatt aaaagaatgg ttagggacct taatattgat atagacgttg
     2341 tagggtgtcc aattataagg gaagaggatg gactagctaa aagttctaga aacacatact
     2401 taagtttaga ggaaagatct tcagctacta ttttaaataa atctttaact ttagctaagg
     2461 aagctttaaa taatggagag agagacagct taaaaataat tgagataata agtaaaaata
     2521 taaatactta taatttggca aagattgatt atgtagaagt tgttgattct ttatcattac
     2581 aaagagtaaa ttatattgaa aaatcagttt tagttgcaat agcagtattt ataggaaaaa
     2641 caagattaat agataatttt acatttgaat tacaataggg ggctataatg aaagttacaa
     2701 tgttaaaagg aaaaatacat agagctacag ttgaacaagc tgagttagat tatgtaggaa
     2761 gtattactgt tgatatgaat ttattagaag cagcaggaat atatgaatat gaaaaagtac
     2821 aaatagttga tgttaataat ggaaatagat ttgaaactta tacaatagct ggagagagag
     2881 gaacagggat gatttgcttg aatggagctg cagctagatg tgtatcaact ggagataaaa
     2941 taattttaat ggcatattgt gaattaaatg aaaatgaggt taaggatcat agacctaagg
     3001 ttgtttttgt cgatgataat aataaagttg aaagagtaac atcatatgaa aaacatggaa
     3061 ggttatcaga tataattctt taggttttgt aatgttattt atatatagct agactattat
     3121 tgaaatattt attgattact aattggatag atgtcaataa agtagacaca aaaagagaag
     3181 atacagactg tagacaaagt ccattttatg tgaatcggct acactagact agacagaaaa
     3241 aataaggtgt gtagaataat aaaaaacaca ctggaggatt tttcatgtca agacgtcaac
     3301 gaagaaccta ttcaaaagaa ttcaaacaac aaatcgtcaa tctctatctc gctggtaagc
     3361 ctcgcgcaga aattattcga gagtatgagc ttacgccttc ttctttcgat aaatggatga
     3421 agcaagcaca atcaacgggc tcattcaaaa aaagagacaa cttaacacca gaacaagcag
     3481 aattgatcgc actaagaaag aaaaataagc aactcgaaat ggagaatgat attttaaagc
     3541 aagcggcgct gatattcgga cgaaaagaca agtaattgat gccaacaagc ataaatattc
     3601 catatcagcg atgtgcaaaa ttctaaatat ttctcgtcag acctactatt atcaa
//
LOCUS       DARPZF010000119         3535 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.126, whole genome shotgun sequence.
ACCESSION   DARPZF010000119 DARPZF010000000
VERSION     DARPZF010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3535
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.126"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(185..742)
                     /locus_tag="SLE65_002825"
     CDS             complement(185..742)
                     /locus_tag="SLE65_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450050.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(921..1532)
                     /locus_tag="SLE65_002826"
     CDS             complement(921..1532)
                     /locus_tag="SLE65_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450051.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSARYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(1645..1902)
                     /locus_tag="SLE65_002827"
     CDS             complement(1645..1902)
                     /locus_tag="SLE65_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450052.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(2499..2777)
                     /locus_tag="SLE65_002828"
     CDS             complement(2499..2777)
                     /locus_tag="SLE65_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450053.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(2811..3062)
                     /locus_tag="SLE65_002829"
     CDS             complement(2811..3062)
                     /locus_tag="SLE65_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450054.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         1078 a          725 c          470 g         1262 t
ORIGIN      
        1 tatttgccac tttgattcgt ataaagctaa caactattaa ctcctctcag ctaatagttg
       61 ctctcttttt tattcagatt catttttgct gatcacagcc tagtatttca atggttttga
      121 acactaaacc aaattgttcc attacaacat tcactggctg atgaaatgga ttagtagatt
      181 tcgattattc aaagcgattt tctattggtg gatcgtgttc ccaactaata agacggattc
      241 caaacctatc gtacagatct tctaaaccac ttataaattt tgcacctatt tcaggtgttt
      301 tattgcgtgg atattctatt gttacgccat taaatggata ccaattagga ttaggctctc
      361 tttttttctg tacatctccc atagaatagt tagcactttc tgggacataa tatattcttc
      421 gaccatcctc taattcatct aataagatat ttcgtgatcg tctatcactt gctaaatgta
      481 gacgccacgt gcgataccat gccatgctac ctgcatctgc agaaaatcca tcaaataatg
      541 caacaattgt atcttctatc acaatccttt ccccatctac ttcatattct aatctaaaat
      601 caaactcccc tcgggtaatt tctggtcttg gtggcttagg acccaatatt attctactta
      661 aaaccgcatt cgttcccaga tgaaacacag ctataacaac aataatgatt aatattttgt
      721 ttctatttga taaatttctc attattcgca catcacctct acattctcac atattagttc
      781 gtaatactcc tttaatatca aaatatctac tggtcgtaat aatattcgct atgaattcct
      841 actactcgta taagaaaggc caaatcatca gcttttactt gctgatgatt tggcttgttt
      901 ctatttatcg taattgtttt ctaatcacca aaattgttaa caatcggttc agatatttcc
      961 cagttgatta aggtaattcc gtattgtgtc aaaacttctt gcgcttctcc gaaattaagt
     1021 acagttctta tgtatccact ttctcctaat ataaagtcta cctctctttt aaaaccttcc
     1081 tcgagatttc taagggctat atgtggtttt aatgacattg attgtacatt ttcccccata
     1141 taatatcgcg cacttcctcg actaaaatag attcctagat cgtccccaaa aggtagatct
     1201 tctctaccac tagctaatct acttctccat cttcgttctc ttttcataga acctgcgctg
     1261 aactcacacc cgttaaactc agctatgaca gtatcttcaa ttatgttaat ctgtccatct
     1321 agttcgtatt caatcctaaa tggaaattct ccataggtga tttccggttc gggtatttta
     1381 ggtgagatta atgcaaagaa aggaaatatt aagcttggca acatcaaaaa aactcctcct
     1441 atgatcacaa ttcccgatgt aatccaaaat ataatttgta caattctcat tgatccattg
     1501 tattccattt tattccccct attactattc atatccgcct atctatatcg atcttccaat
     1561 gcagagataa ttgcttccat accttgattt tttactgagt tacctatgcg agatatcatt
     1621 ctccactaag gtgcatcata ttgtctatct aacatgatta attctccaat aggtgtatac
     1681 tcctccaaaa acaacattta atgcatctcc ctcgacaaca taagctacca tgtttgctgt
     1741 atatgtgttt gagtctaatt cataagcaga taaatttact gtcgctggat taaatataat
     1801 cgcattcgta tttatagcta ctgaatttgc tgcttcagca ccaccttttg aatgtccgat
     1861 cattgtgatt tcaatagtag gatttacgtg gacagccctc accgtttacc ctgaccatta
     1921 tagaaatcgc ttactttttt gaactacgca acaaaggata caatgctcct aacttcactg
     1981 tctccatttt tgtccactaa ggaatataaa aaataggcat taattcattt aattcggtca
     2041 caacacgtta ccttttaaat cattatactg tatctcatac attattatca ataaactatt
     2101 ataaaaatgc aaaaaatgct ttatcaatct attttgtaat tggtcataat atcattgaaa
     2161 tcataccctg tatcgatttt tcctatgaat ctcgtctatt tgtgattgac gaaaaagagg
     2221 caagacagac actggaatgg taattttacc cactattttg ctccaactat ttgtaatcgt
     2281 acccactttt gaaataccga gatgatcatt ttaattgata tgctgattcc caagcaaaac
     2341 cccaagaaat taaatgctct atcgcatcta gcttcttggg ttttgcttat ataaattcca
     2401 acatttaaat tttttatgct gttcggtctc agaaatgccg tttttgctta tatcacaata
     2461 tcaagatgtc aaattattcg tgttgccgat gactttgatt aatttttttc aaattgttta
     2521 ttaagactaa tgctgtcttt ttgcagatac caatgttcga actttttaac attatcatat
     2581 gatcctgcaa gttttaactt cttaccatta gatgttatca aagttataat taaccttgcc
     2641 tttttcccat taggatcttt tattttatga attttctgca ggtaatctct cctaatggca
     2701 gctattttta cctcatcagt gctgataaac cattgatcat ccacatacat actgcctgtt
     2761 atgttgtgtt tttccatttc ttccgagaac gaaaagttta aggctcgttc ttacttccaa
     2821 agttgaatga gtccatggat tggacttagt gtgagaattg agaacaacaa taagaatcca
     2881 tatcctcccg caaacatccc taaggctata ctgtctctcc atccataagt aggattagaa
     2941 gagaaaagag tcaccgtttg taataatatg aaaaggaata atccagcaca aacaccaaag
     3001 ataacaactc caaacattga atttttatac aatgaccatt tatttatagg cttttctttc
     3061 attttacttc cccctactgt tctgttcaca cggaatgaat tcaaagttca taagccctcc
     3121 tctttgaaca tatgaatacg acttgctaac tatactttaa aaaagcttgt tttaagcggt
     3181 tataggcgag ttgtaatctc tattcatctc attagcaaat aacttgccga aaagtctact
     3241 gaaattaaag cagatagtgg aagaattatt tagccaggat agacactatt tgtgaaacac
     3301 atgtctttac ttttgaaatt ctatgatgaa aagccttgga atacagtagc tcttaattgg
     3361 taatactttt tccattataa ataacctctt ttcattttat atttatcccc tctaaaaata
     3421 atatctaatc taatatttta aacttatatt tccctcgctg tgctaataga gcattactaa
     3481 ataaatagaa actagaaaaa agcattacgc ctgccagaat aaaccaatta tttgt
//
LOCUS       DARPZF010000120         3371 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.127, whole genome shotgun sequence.
ACCESSION   DARPZF010000120 DARPZF010000000
VERSION     DARPZF010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3371
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.127"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..135
                     /locus_tag="SLE65_002830"
     CDS             <1..135
                     /locus_tag="SLE65_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEI8450055.1"
                     /translation="FNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA
                     "
     gene            113..1588
                     /locus_tag="SLE65_002831"
     CDS             113..1588
                     /locus_tag="SLE65_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HEI8450056.1"
                     /translation="MESFVSLNLTNNTSKKNQPKDIKDIVDTRMYKERDDLNYTLIIN
                     KDGNYSWRPLVLLHPILYVDLVNCLTKEDHWEELKKRFSEFKKDKNINCYSIPVEASK
                     GSKRTDLGETILNWWEYFEQKSLAQNIKYQYCMFTDIADCYPSIYTHSITWAMYGKEK
                     VKNDENKCSGSLGDKIDKKISGMQHNQTNGIPQGSVLMDFVAEIVLGYVDLRLSKELK
                     KLENLKDYKVLRYRDDYRIFSNNRNDLEQIMKVLSEVLYDLNFKLNSSKTKLSDDIII
                     DSIKKDKLYWEEIKASIRMNATNLDGDREIRYSINLQKHLLEIKKLADKHPNSGQLKK
                     ALSEFNKERIIKITSKPNDLLPLIGILVDIMINNPGSLPQCVLIIGQLLNFENESKAR
                     EIVEMIINKYALKPNTEFMMIWFQRLTTIFGEMFDSVLSSEFVSKIKDPVSNQMFSVD
                     WLNEDAKKSFYEGTIKDEEKYIKMSKKIYITEFDDFNDYPF"
     gene            1926..>3371
                     /locus_tag="SLE65_002832"
     CDS             1926..>3371
                     /locus_tag="SLE65_002832"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEI8450057.1"
                     /translation="MTEQIEKNSKSLYQALWNSADILRSKMDANEYKSYLLGLVFYKY
                     LSDNMLRYVSVLLEEETDDLNKAQDLYVEAFKDADIKDDLLYELKDEFSYTIAPALTF
                     TAQVAAIHDGSFQLEDLVQGFRDIEQSSENFENLFEDIDLYSKKLGSTPQKQNKTIAD
                     VMKELEGLNMAGHAGDVLGDAYEYLIGQFASESGKKAGEFYTPQPVAKLMTQIVLQGK
                     EDKKGFSVYDATMGSGSLLLNAKKYSHQPGTISYFGQELNTSTYNLARMNMILHGVPI
                     ANQHLHNADTLDQDWPTEEPTNFDGVLMNPPYSAKWSADKGFLDDPRFSAYGVLAPKS
                     KADFAFLLHGYYHLKDTGVMAIVLPHGVLFRGGAEGKIRKALLENGAIDTVIGLPANI
                     FFNTSIPTTVIILKKDRAKKDVLFIDASQDFEKIKTQNTLRDYHIDAILEAYKTRTIK
                     DKYAYVAEFDEIVENDYNLNIPRYVDTFEEEE"
BASE COUNT         1240 a          536 c          602 g          993 t
ORIGIN      
        1 ttcaaccaag tcaatcaagg attcatctca tccgttgcgt ccaaaagaaa ccatatccct
       61 agaaaatcac taaattacca aacaccatta gaagtttttt tgagttacgt aaatggaaag
      121 ttttgtctcg cttaatttga caaataatac ttcaaaaaaa aaccaaccga aagatataaa
      181 agatattgta gatacacgaa tgtataaaga acgtgatgac ttaaactata cgcttattat
      241 caataaagat ggaaactatt catggcgtcc tctcgttcta ctacatccta ttctatatgt
      301 agatttggtt aattgtctca ctaaagaaga ccattgggag gagttaaaaa agaggtttag
      361 tgaatttaaa aaagataaaa atattaactg ttattctata cctgttgaag cttccaaagg
      421 ttcaaaaagg acagatcttg gtgaaacaat actaaactgg tgggaatatt ttgaacaaaa
      481 aagcttagct cagaatatta aataccaata ttgcatgttt actgacatcg ctgattgtta
      541 tccatcaatt tatactcact ctataacatg ggccatgtat ggtaaagaaa aagttaaaaa
      601 tgatgaaaat aagtgttcgg gctcacttgg cgataaaata gataaaaaaa tatctggaat
      661 gcaacacaat caaacaaatg gtatccctca gggttccgtt cttatggatt ttgtagcaga
      721 gatcgttcta gggtatgttg atttgagatt atcgaaagaa ttaaaaaaat tagaaaattt
      781 aaaagattac aaagtactca gatatagaga tgattataga atattttcaa ataatcgtaa
      841 tgatttggaa caaattatga aagtgttatc agaagtctta tatgatttaa attttaagtt
      901 aaattctagt aaaacaaaat tatcagatga tattatcata gattctatca aaaaagataa
      961 gctctattgg gaagaaatta aggcaagtat aagaatgaat gccacaaact tagatggtga
     1021 tagagaaatt cgttatagta taaatttaca aaaacattta ttggaaataa aaaagttagc
     1081 agataagcat cctaattcag gccaattgaa aaaagcactt tctgagttta ataaagaacg
     1141 cattattaaa atcacttcaa agccgaacga tcttttacca cttattggta tcctggtaga
     1201 tatcatgata aataacccgg gttctttgcc gcagtgtgtc ttaattatag ggcagttatt
     1261 aaatttcgaa aatgagagta aggctagaga aatagttgaa atgattataa acaaatatgc
     1321 tttaaagcca aatactgaat ttatgatgat atggtttcaa agattgacca ccatttttgg
     1381 agaaatgttt gatagtgttt tatcatccga atttgtatct aaaatcaaag atcctgtctc
     1441 taatcagatg ttttctgtag actggctaaa tgaagatgct aagaaatctt tttatgaagg
     1501 gaccattaaa gacgaagaga aatatattaa aatgagtaag aaaatatata ttactgaatt
     1561 tgatgatttt aatgattatc ctttttaagt gaaaatttag aatgaatata aaaaacatta
     1621 caatctaatt tttttaaaaa aatgttatat cggaagtaat ctcttgattt ctatactata
     1681 agataagaaa accactattt aacaaggtta ttcgaacctt attttaagtt acttattatt
     1741 taatgtatcg aaaaaggtga aataggtttg ttataataag aattaagtaa gacatgaatt
     1801 gtctaagcaa atgtagctta tccatttcat taaaatacat atggtgaaaa aacaagttca
     1861 aatagtaact aattttttaa aaaactgatt tataaaaaat acaacacgaa tgaggaaaat
     1921 aaccaatgac agaacaaatc gaaaaaaatt caaaaagctt atatcaggca ctgtggaatt
     1981 ccgcagatat cctgcgttca aaaatggacg ctaatgaata caagagctat ttactaggct
     2041 tggtctttta taaatactta tccgacaaca tgctgcggta tgtctccgtt ctattggagg
     2101 aagaaacgga cgacctaaat aaagcacaag acctttacgt tgaagcattt aaagatgcag
     2161 atataaagga tgatctcttg tatgaactaa aagatgagtt ttcatatacc atcgcacccg
     2221 cattgacctt taccgcgcaa gtggcagcca ttcatgatgg atcttttcaa ttagaagacc
     2281 tggtacaagg tttccgtgac attgaacaat ccagcgaaaa ctttgagaac ttatttgaag
     2341 acattgatct gtattctaaa aaactggggt caaccccaca aaaacaaaat aaaaccatcg
     2401 cagatgttat gaaagaatta gaagggttaa acatggcggg gcatgctggc gatgtcttag
     2461 gcgatgccta tgagtactta attggccaat tcgcatctga atccggtaaa aaagccggtg
     2521 aattctatac cccacaaccg gtcgcaaaat tgatgacaca aattgtttta caaggaaaag
     2581 aagataaaaa aggcttttct gtttacgacg cgaccatggg ttcgggctcg ttacttttga
     2641 acgctaaaaa atattcccat caaccgggaa ccatttctta tttcggacaa gagttgaata
     2701 cgtctaccta taatttggcg cgtatgaaca tgattttgca tggggttccc attgccaacc
     2761 aacacttgca taatgcggat accttggatc aagactggcc aacagaagag ccaacgaact
     2821 tcgatggggt gctcatgaac ccaccgtatt ctgcaaaatg gtcggctgat aaaggcttct
     2881 tagatgaccc acgcttctct gcctatggcg tattagcccc taaatcaaaa gcggactttg
     2941 ctttcttatt acatggctac tatcatttga aagatacggg cgtcatggcc attgttttgc
     3001 cacatggggt gctctttaga gggggcgcag aagggaagat acgcaaagcc ttgttagaaa
     3061 atggtgccat tgacaccgtc attggcttac ctgctaacat cttctttaat acgtccattc
     3121 caacgaccgt aattatcttg aagaaagacc gtgcgaaaaa agatgtgctc tttattgatg
     3181 cgtcacaaga ttttgaaaaa ataaaaacgc aaaatacgct acgagattac catattgacg
     3241 ctattttaga ggcctataaa acccgtacaa ttaaagacaa gtatgcttat gtcgcagaat
     3301 ttgatgaaat tgtggagaat gattacaact taaacattcc ccgttacgtg gatacctttg
     3361 aagaagaaga a
//
LOCUS       DARPZF010000121         3316 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.128, whole genome shotgun sequence.
ACCESSION   DARPZF010000121 DARPZF010000000
VERSION     DARPZF010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3316
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.128"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            278..787
                     /locus_tag="SLE65_002833"
     CDS             278..787
                     /locus_tag="SLE65_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEI8450058.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="SLE65_002834"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="SLE65_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEI8450059.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="SLE65_002835"
     CDS             2322..3302
                     /locus_tag="SLE65_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8450060.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
BASE COUNT         1185 a          531 c          656 g          944 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaa
//
LOCUS       DARPZF010000122         3272 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.129, whole genome shotgun sequence.
ACCESSION   DARPZF010000122 DARPZF010000000
VERSION     DARPZF010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3272
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.129"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(368..1486)
                     /locus_tag="SLE65_002836"
     CDS             complement(368..1486)
                     /locus_tag="SLE65_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450061.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1957..3264
                     /locus_tag="SLE65_002837"
     CDS             1957..3264
                     /locus_tag="SLE65_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEI8450062.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
BASE COUNT         1025 a          679 c          589 g          979 t
ORIGIN      
        1 tttttaaacg gtgttccaga agtagcttct tcggaaataa gccgaaattt cacaaaaatt
       61 tgagaaataa tttttgtcaa tctcttctta tttcttgaag ctgaccactt ctgtcacaac
      121 ctcttcctta aacggtgttc aaaagcttgc atctgcggta ataagcccac caaacaaaaa
      181 atatgaagag ctatttttgc ttgctgttct tattacttga tgcagaacag ctttttcaca
      241 acctctcata cacggtgttt aatcagctga ccttcggtat tagctcaaaa aacggaaaaa
      301 tatgtgaaac tatttttccg tttgtttctc taatactcag gtcaaaacac tgatttcaca
      361 acctctttta ataacgaaga atcgctgtca gactcttttc atctggcgca tctttttgat
      421 ccaaaataaa cactttcccg ccattaatga tcacatcatc tgctaatgca ttcaacactt
      481 gacgccgatc atattctgtt tcaggatctt caccgaaacc atcagctaag tttgacgtag
      541 cgataaataa atgtgacact tttccttctt tcgcagctgg aacgatatca actaactgat
      601 cgatgaattt cttatctaag agtttattgt attcttttga ttcttgagct gcgagttcac
      661 ttgacagctt cttcgcccct tcttcgatat ctctaaagga tagctgcgca ggagaagcag
      721 aaatcgcaac gtctgcacaa taatagggat ttttagcaat ttttttgaac atcgtctgat
      781 tttctggtaa tgcaaataaa taaatcggcc attgttcagg attttcgaaa gaatccttca
      841 agtacgtatc aacagcttgg taatagttga cccaatcgat ctctacttct tcatcttttg
      901 gatttacgcc atggaaagtt actccatctc gggctccgcc tcctccatta gaagagaagt
      961 tcaaaccgcc acctgtcagt tcagatccca atgcagtaac gacatcaacc ggtgcccctt
     1021 ctggtagaga tacttctttt acttgtttgt tgctgacctc atacaatttc atggagtcgc
     1081 ggttcaatcc caataaataa taagaatagt tgaactgccc atttttgata atagccagta
     1141 aataaggaag atcacttaca tagtattgat cgtctaccgg gatactcaaa cgatggatat
     1201 aggtctggtc agcagttata atgaccgcta cactcgtagt tgcactacgc caaaacgaag
     1261 gatctcctaa caaattttca attttttctt ggaacgggga ccagtcatgt tcggaatatt
     1321 ttttctcaaa acgtttcttt gcttctttcg caaaattttt gaatttgatc tgatcttttt
     1381 ccacatcttg atgggcgaca tgcgtattca gcatgatcgt gacgaatggt cctttagcgc
     1441 cttctgaagt caattgtgtc aataattctt tatccttttt tgccataaac gtacccctcc
     1501 taaaaaaatc attcctttgt ttctatctaa agtctaccac aacactattt ttccatacaa
     1561 taaaacgtat ctaaaaaaat aaaacggttt ctacggtttt aaatttagct atttttttaa
     1621 gttatcttca taatttcctc aattatttag ccccagtctt caactattct tcatgaaatg
     1681 ctgataaact aagaaaaaga ataaaagagg tggatcttat gcatttgatt atgattttca
     1741 gtttattaag tattatcagt ttatttgctt tcagcgcttc ccgcttatta gatgcggaaa
     1801 cacagcctat tcctgtaaaa gtacgtaaaa acgaccgcta aacttccata acgcgcgttc
     1861 ttatcctaaa gttttttcag aaacattgaa actctctccc ctctctgata aaattttaat
     1921 ttgtagcgaa acaaattaat tacaaggaga tcggatatgt ccataaaaaa aacacgtcta
     1981 gtcctattat tggctagtct cattctttgc cttgcttctt ttctaccagc tgttgctgtg
     2041 caagctgaag atacgttcaa agtaaatgca aaagcagctt ttgctgtaga tgcgcaaagc
     2101 ggtaagattc tttatgatca agatggagaa aaaaccatgg ggatcgcttc aatcacaaaa
     2161 atcatcggtc tttacatcgt ccttgatcaa gtaaaagaag gaaaactgtc atggggtgat
     2221 aaagtttcga tttcagatta tgcagaaaat ttgagtatca ccccagattt atcgaatgtt
     2281 cctttgcata aagaaaacac ctacactgtc aaagaattat tcgactctgc aatcatccag
     2341 tcagccaatg cttcaatggt ggccttggca gaaaaaatct ctggcagcga agctaaattc
     2401 actgaacgaa tgaaagaaca attgaaagat tggggaatca aagatgcaac aatcgttaat
     2461 gcatcaggat tgaacaactc ttatcttggc gaaaaccgac cagaaggcac tggagaaaac
     2521 gacgaaaatc aaatgtctgc tcaagatgtg gccatcgttg cccgccattt gatcttggat
     2581 ttcccagaaa tactggatgt atcaagtact acgacccaaa tgtttggcga aaatacgcaa
     2641 tcaccagtgg aaatggtcaa ctggaactgg atgctcccag gattcgttaa ttacaaggaa
     2701 ggcgtggacg gattaaaaac tggtacgact gagcttgcag gtgcttgttt cgttggtacg
     2761 atcactaaaa acgatcaacg gatcatcact gtcgtattga atgcggacgg ccatgcggaa
     2821 aacccgagtg cccgcttcaa tgaaacagac cgtttgatgg actactgcta tgacaattgg
     2881 tcagaaaaag agctcggaaa agctaacgca agtattccta gtctaaaaac cattgatgta
     2941 aaagacggaa aagaatcaac agttcctgtt gtgcttaaaa gccctgtaaa agtatgggta
     3001 cgaaacgata tggatactgg caaattaacg atcacgccaa cacttgacaa gaagcaagtc
     3061 actgacaatg agatccaagc acctatggat aaaggtacaa aaatcggtac cgctacgatc
     3121 accttggcag acgataaatt aggctattta gaagacaaca atgcaccatc aacagagatc
     3181 attacggata aaacagtgga aaaagcgaat atattcgtga ttggctggcg acgcgtcgca
     3241 gaatttttcg gcaacttgtt ttaattgaac aa
//
LOCUS       DARPZF010000123         3252 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.130, whole genome shotgun sequence.
ACCESSION   DARPZF010000123 DARPZF010000000
VERSION     DARPZF010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3252
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.130"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            3..587
                     /locus_tag="SLE65_002838"
     CDS             3..587
                     /locus_tag="SLE65_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEI8450063.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(664..1857)
                     /locus_tag="SLE65_002839"
     CDS             complement(664..1857)
                     /locus_tag="SLE65_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEI8450064.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            1921..2301
                     /locus_tag="SLE65_002840"
     CDS             1921..2301
                     /locus_tag="SLE65_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEI8450065.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            2375..2737
                     /locus_tag="SLE65_002841"
     CDS             2375..2737
                     /locus_tag="SLE65_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450066.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1102 a          528 c          615 g         1007 t
ORIGIN      
        1 atatggcatt cccacaacta gatttaaaaa gtgaaaaagg accaaaagct gttatcaaaa
       61 caaaccgtgg tgacattact gttcaattat tccctgaact agcaccgaag acggttcaaa
      121 atttcattga actttccaaa aaaggttatt atgatggcgt gatttttcac cgcgttattc
      181 ctgatttcat gatccaaggc ggcgatccaa ctggaacagg aatgggtggc gaaagtattt
      241 atggcgaaag ttttgaagat gaattcagtc gtgaactgtt caaccttcgc ggagctttat
      301 ctatggcaaa ttcaggtcca aacacaaacg gaagccaatt ctttattgta aataacacaa
      361 atgtgccagc taatatgctt ggacaactag aaggtgctgg attcccatca gaaatcattg
      421 aagcgtataa aggtggcgga actccttggc tagatttccg acatacagtc tttggacatg
      481 tactagaagg gatggacaca gtagatgaaa tcgcaaatgt acaacgtggt ccacaagacc
      541 gacctgtaca tgatgtagtg attgaaacaa ttgaaatttc agaatagttt ggtatggtac
      601 ggagtaatta tgaaaaagga cgaaacctag taaggtctcg tccttttatt ttgaataaat
      661 gatttaatcg attgtctcta aagcatactt gattcgatta agtccttcca gtaaagtttc
      721 ttctggacaa gcaatattca agcgcatatg cccatgaccg gaaggaccaa acgtgatgcc
      781 aggatttaat acgacttttc ctttccgaac aagagtgttc tccaattctt ggtcgtctga
      841 aatataggcg gtaaaatcta accacattaa gtaagttcct tcagggttca ttattctcac
      901 tttcggaaga tactgttcaa aaaactgatt aactgtttga acattttttt ctagataagg
      961 aatcagttgg cttaaccatt ctccacccgt ctcataagcc gcttgggttc caatcagtcc
     1021 aaaagtgttg atttcgtgct gttggttcat cactaaatgt ttttcaaaat cagctttcat
     1081 ctctggattt ttgataaata ccattgaatt tttgattgca gctagattga aagtcttggt
     1141 tgcggaagta aaagcaacta gtagatcatc taaattagga tcaatcgtta gcatggaagt
     1201 aaatgtatga tcgaataaag ttaaatcttg atggatctcg tcactaaaca gaatcacttg
     1261 atgttttaaa cacaattcgc ttaactgttt caattcttct ttgctccaaa cacgccctcc
     1321 aggattgtga ggattgcata aaatcattgc ttttacattg ttttcttcga tttttttctc
     1381 catgtcagac aagtccatga tgaaatgatt atttttttct agcaaagagc ttcgaacgat
     1441 gtgacgttga tttgtttcta taatagagga aaatggagga taaactgggt catgaatcaa
     1501 aatagaatcg cctggttttg taaaagtttg tactgctgca gctaaactgg ttaacacacc
     1561 acttgtaaaa acgatatttt ctttcgtcaa ctccacagca tggtgttggc gttcccaatg
     1621 aatgatagcc tgatatagtt tatcagacag agtggcataa ccaaagattc catgtttgat
     1681 gtattcacta aacgctttag ctaccccacc gggagacaag aagtccatat ctgctaccca
     1741 caaaggaagt aagtcatcca tttgatatgt ctcagcaatt gcgtcccatt ttacactttc
     1801 tgtatctttt cttgaaatct gtttatcaaa ttcgatcatc ttaagacctc cagtcatttt
     1861 cgtcgcttct ttttttgagc tatttacagt ataatgataa atgcgaagag agggaagtag
     1921 atgacttata aaattggaca aataattgaa ggaaaagtga cagggataca gccttatggc
     1981 gcattcgttt ctcttgataa cgagacgcaa ggacttattc atgtttcaga agtacaatcc
     2041 ggttatacga aaaatatcca ttcattgtta aaagtcggac agccagtaac agttcagatc
     2101 atcgacattg atgaatattc caaaaaaatc agtttatctt taagaacgtt agaaaaaaca
     2161 aatccagctg ttccatatcg cagaaaaagg tatttcacga ataaaaatcg taagatcgga
     2221 tttaccacta ttgcggagca gttacctatt tggatagaag aagcattatc tgaactagaa
     2281 cggaaagaaa ataagaaata aaaagtgtat tttttctgaa aatgtgctag aatttttatg
     2341 taagccatag aacaagttga tcgaggtgga aattttggca agcaaaagag ttgctggtac
     2401 aattatgttg catttggagg atggtactaa aaaatttttg gtccattcaa ttgatgacaa
     2461 gttggaattt gcgttagcgg aactttctga aggaaagact ggtttagcga atatacttaa
     2521 tttcttaaaa gaaatagttc atatcgatgt tagcaagatt agtttgatgg aattgacaaa
     2581 tacacatatt aaagaggaaa atgttccgtt gtttgtcttt gaaactgaac aaaagaatca
     2641 aagagaagaa ttaggcgaag gatatatttg ggaagaacca ggtcaaatgc gctctgttct
     2701 tggaacttac gaagtagagg gagtgccttt cttctaaaat acagattaag cgaacaaaga
     2761 agtttgaatt tttttcaaac ttcttttttt attgtttggt ccaaaaaata caatgaaatg
     2821 ttctgctaaa gatagttttt tagtgcattt tattttcaaa atatgttgaa aacggttgta
     2881 taacgaataa taataattga tcgaaaaatc atttcacaaa gtaatgctta atttatagtt
     2941 gaccaaggaa gaaatacatg ataaatttaa cagcgttgat tctgaagtgg atgttatatc
     3001 acatttctaa aaaatttaaa aaatagttat tgacatgtta ctaacgacat gataagataa
     3061 ctgagtcgtt aaaaaagaac cacttgcgaa gcttgattct atcgaaaaaa acttcaaaaa
     3121 agttcttgac aaataacaaa cgataagtta tgataaatga gttgctgaaa gatttcgaaa
     3181 aacgaaatcg aaaaaaactt ttaaaaaaga gttgacaatc gtttgtctct ctgatatgat
     3241 ataaaagttg ct
//
LOCUS       DARPZF010000124         3196 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.131, whole genome shotgun sequence.
ACCESSION   DARPZF010000124 DARPZF010000000
VERSION     DARPZF010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3196
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.131"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            585..1757
                     /locus_tag="SLE65_002842"
     CDS             585..1757
                     /locus_tag="SLE65_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HEI8450067.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
     gene            complement(1887..>3196)
                     /locus_tag="SLE65_002843"
     CDS             complement(1887..>3196)
                     /locus_tag="SLE65_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HEI8450068.1"
                     /translation="SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHY
                     PKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIR
                     AYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDS
                     IEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEY
                     SYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISEC
                     TIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCN
                     HLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEK
                     AKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT         1103 a          571 c          413 g         1109 t
ORIGIN      
        1 tagtagattt aaaactttgc aacagaacca agacactcct cttaatatac agtcctattg
       61 tataaagtgt tactatatac atagtaactg tatacataaa aaaagtcaag tattagaaaa
      121 aagttcaaaa gatcaagtgt gcgcttcgct cccactcccc tcgacgtttt agtagccttt
      181 ccctcacttc gttcagtcca agccaactaa aaagttttcg ggatacattc tccttctctt
      241 cctaataatc aattaaaatt ttaatcttta tatttctgct aatcactcag gaaacagtac
      301 agaaaaacaa acacgtatca tagatataaa tgtaatggca tagtgcgggt tttattttca
      361 gcctgtatca tagctaaaca aatcgagttg tgtgtccgtt tttgggcgtt ctgctagctt
      421 gtttaaagtc tcttgaatga atgtatgttc taagtcaaaa aactctgaca gcgcctttat
      481 atagataaag tccgtataat tgtgtaaaag taaaaaggcc atataacagt ccttttacgg
      541 tacaatgttt ttaacgacaa aaacataccc aggaggactt ttacatgacc caagtacatt
      601 ttacactgaa aagcgaagag attcaaagca ttattgaata ttctgtaaag gatgacgttt
      661 ctaaaaatat tttaacaacg gtatttaatc aactaatgga aaatcaacga acagaatata
      721 ttcaagcaaa agaatatgaa cgaacagaaa accgacaaag tcaacgaaat ggctattatg
      781 agcgcagctt tacgacacgt gtaggcacgc tagaattaaa agtacccaga acacgtgatg
      841 gccatttttc acccacagtg tttgaacgtt atcaacgaaa cgaaaaagcc ctcatggctt
      901 caatgttgga aatgtatgta tcaggcgttt caactcgtaa agtatcaaaa attgtggaag
      961 aactttgtgg taaatccgtc tctaagtcct tcgtttctag cttaacagaa cagctagaac
     1021 ctatggttaa cgagtggcag aatcgtttat tatcagaaaa aaattatcct tacttaatga
     1081 ccgatgtact ctatataaaa gtacgagaag aaaatcgagt actctcaaaa agctgtcata
     1141 tagcgattgg aataaccaaa gatggcgacc gtgaaattat cggcttcatg attcaaagtg
     1201 gcgaaagcga agagacctgg acaacatttt ttgaatacct aaaagaacgc ggtttacaag
     1261 gtacggaact cgttatttct gatgcgcaca aaggattagt ctctgccatt agaaaatcct
     1321 tcaccaacgt aagttggcaa agatgccaag ttcacttcct aagaaatatc tttaccacca
     1381 ttcctaaaaa aaattcaaaa tctttcagag aagctgttaa aggaattttt aagttcacag
     1441 atattaactt agcgcgtgag gctaaaaatc gattgattca tgattatatc gatcaaccaa
     1501 aatattcaaa agcttgcgca tcattggatg atggattcga agacgccttt caatataccg
     1561 tacaaggaaa ttcccacaat cgactaaaga gtaccaatct aattgaacga ctgaatcaag
     1621 aagtacgcag aagagaaaag attattcgca tcttccccaa tcaaacatca gccaatcgct
     1681 taattggagc cgttcttatg gacctacatg atgaatggat ttattcttca agaaaataca
     1741 tcaattttga taagtagaaa tggtaaaaac attgtatagc attttacaca ggagtctgga
     1801 cttgactcac ttcctttatt atttttcatt tttttaaact atttaatact aatgtctttt
     1861 ataatagctt ttcatatatt atataatcaa tctttataag tccttttata aatttctttt
     1921 ctaccatttt cgataaattc ctgtttaata tttttaattc cataaacaat agtttcaata
     1981 ggataatatt cttcaactat atcttgatat tcttttgctt tctcaatatc tatatttcca
     2041 tacattctta atatatcttc tccaaaattt gttcctattt cttcttcact atcttcaagt
     2101 aagtatataa aatcacaata ttcatctata attccagaat ctccaaaatc aattattcca
     2161 gttaatctat tattgccatc taacaataga tgattacaac taaaatcatt atggcataaa
     2221 cactttttac cctcaaaaac tgttgttgca tttagtcttt ccataaaact ttctatataa
     2281 tctttttcta tatcagttaa atcattataa atagtttcac gcaacaatat atactcttct
     2341 aatacatttt gtttattatc aatagtacat tcactaatat ctgtataatc taaaccgtgc
     2401 atttgtctta aaaaactggc aatatctcgt tttaacaaat tttgttcttc ttctgacata
     2461 gtagaataaa tttctggtgt taaaaaagtt cctttaattt ctttataacc tagtatagat
     2521 aattcatcac taatatacga atattcaata ttaggaattt ttacattagt ttctaaattt
     2581 gtatttaaaa aattatatat tgctttttct tttgcataac cttttttctt attagtacta
     2641 aattttgttt taaaaatgta ttcattatta actaaatatg ccacactatc ataaccacta
     2701 ccgattattt caatactatc tactttgaaa ttatcaaagt aatgctcaat taaatatttc
     2761 attgccttaa catttgtggc attatcatca tatctatatt ccattaaata acaatcttct
     2821 tttttgccct cgtgtaattc atgttctggc aaatcttcaa taattctaaa accagatttt
     2881 tggtatgccc ttattgctct tggattattt ttatgagggt ctaaaataac tgcattagca
     2941 tttctttctt ttttcaaaaa ttcaaaaatc aatttaatat atcttgtacc aattccttta
     3001 ctccaataat ttggctctcc tataaattga tccataccat agactatctc atcagttttt
     3061 ggataatgat aatcagtata taactcatca tacattttat atatttgtcc atatccaata
     3121 ggaacattgt tatattcaat aattactcta aaaacttcat cttcccaagg ctctgtataa
     3181 tgttttttta atgatt
//
LOCUS       DARPZF010000125         3092 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.132, whole genome shotgun sequence.
ACCESSION   DARPZF010000125 DARPZF010000000
VERSION     DARPZF010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3092
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.132"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..387
                     /locus_tag="SLE65_002844"
     CDS             <1..387
                     /locus_tag="SLE65_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450069.1"
                     /translation="TIGISVTGTTIPTFADSTNEPTTVVDNNQELTPLDRNGIAIGNP
                     TNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSRNWKEKRNGYWYY
                     GKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            397..600
                     /locus_tag="SLE65_002845"
     CDS             397..600
                     /locus_tag="SLE65_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450070.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            811..1395
                     /locus_tag="SLE65_002846"
     CDS             811..1395
                     /locus_tag="SLE65_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8450071.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
     gene            1564..2889
                     /locus_tag="SLE65_002847"
     CDS             1564..2889
                     /locus_tag="SLE65_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HEI8450072.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRS
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGILSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQINEEN
                     LDKIIDKIRQKYGFTSIVHASSMLESARSITRSTLVGGHAGGNGGIKND"
     gene            2882..>3092
                     /locus_tag="SLE65_002848"
     CDS             2882..>3092
                     /locus_tag="SLE65_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450073.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAE"
BASE COUNT         1102 a          472 c          620 g          898 t
ORIGIN      
        1 actattggaa ttagtgtaac tggaactaca attcctacat ttgctgatag tacaaatgaa
       61 ccaactactg tagtagataa taaccaagaa ttaactcctt tagataggaa cggaatagcc
      121 attggtaacc caactaacga cttaactgtt actgaaaatt atttaatagt ttctccatta
      181 cttgctcgag cagcttctaa aacgatacga gtgacaggaa cgatgatttt tgataaagtt
      241 ggttggcctt ctagacctcc tcaatcacgg aattggaaag aaaaaagaaa tggttattgg
      301 tactatggaa aattgtattt acaaagttat aaatcagctg gaaacaattg gattgcgact
      361 tattcaggaa ccttaactag aaagtaggga ttttttatgc cagaatttgt gaacacacca
      421 aatttttatc aagatagcga tattctaagt aaaattaatt taccgaaaga agaatcagct
      481 ttacaagttc agcgaacttt acaggagaca caaaaaattc aaaaatcaat ttctaatcta
      541 gaagattctg aagaaaaaag aaaaaaaaga gaccaaaaaa catatcaaaa agaaaaataa
      601 tgattttaaa aaaagagtgt ctagtcgaca ttcttttttt ctaattgaaa gtgttcataa
      661 aatcacccat ttctggacac tttctttttt tgctttattt ttcaaaaaaa caattcattt
      721 catgttcata aacccataac aatatctatg ttcagttaaa ctatatggat aaagttatgt
      781 tacaataaaa ttaatgaagg agtgattttt ttgaaaatag gatacgcccg ggtatctact
      841 ggtttacaaa atttggattt acaagaagac agcctaaata aatttggttg tgaaaaaatt
      901 tttactgatc atatgagtgg ggcaaaaagt aatcgaccag gattagaaat ggccattgat
      961 tttgttcgct ctggcgatac acttgtcgtt tggcgcttag atcgtttagg tagaaatatg
     1021 gaagatttga tttcaatcgt caatcgactg aatgagcgtg gtgtgagttt tcatagtatt
     1081 caagaaaata ttacgatgga caaatcaagt tctacaggac agctcatgtt tcatttgttt
     1141 gcggcatttg cagaatttga gcgtaatttg atcctggaac gatccgcagc aggacgagca
     1201 gctgctcgtg caagaggacg gtttggtggt cgtcctgaaa aattgtctga acaagatttg
     1261 gaattactga agactttagt ggatagcggt acacctatta agactattgc ggaacggtgg
     1321 aacgtctcaa gaaccaccat ttatcgttat ttggcaaaaa tggaggagaa aaatggaaag
     1381 acaaattctc attagttttt gtcatttaat gctgaaaatt tttgccattt atctagaaaa
     1441 gtgacaatag tatgagaatt ttttgtaagt gtctactgat aacttattct caaatattta
     1501 gctatttctt ctttacaaca tcgaacatat gtttgtataa tgtggaagaa tggagtgtta
     1561 tttatgatgg attattcaaa agagccagta aatgattact ttttaatcga tatgaaaagc
     1621 ttttacgcaa gtgtcgaatg tatagaaaga aatttagatc cattaacaac agaacttgtt
     1681 gttatgagtc gatctgataa tactggttca ggattgatat tagcttcttc tcctgaagca
     1741 aaaaagcggt atggtattac aaatgtgagt agaccacgtg acttaccaca accatttcct
     1801 aaaacactac acgttgttcc accacgtatg aacctatata tcaagcgaaa tatgcaggta
     1861 aataatattt tcagaagata tgtggctgat gaagatctac tgatttactc gatcgatgaa
     1921 tcgattttaa aagtgacaaa atcactgaat ctttttacga ctgaagaaac acgaagtcag
     1981 cgaaggaaga agctcgctca aatgatccaa gaacgtatta aagaagagtt aggtttgatt
     2041 gctacggtag gcgtcggcga taatcccctt ttggctaaat tagccttaga caatgaagca
     2101 aagcataatg aaggatttat tgcggaatgg acgtacgaaa acgttcctga gaaagtatgg
     2161 aatattcccg aaatgacgga cttttgggga attggttcgc gaatgaaaaa aaggctcaac
     2221 caaatgggaa ttttgagcat tagagacctt gctaactgga atccttatac gattaagaat
     2281 agattaggtg tgattggatt acagctgtac ttccatgcta atgggatcga tcgaacagat
     2341 atagcaatcc caccagaacc gacaaaggaa aaatcatatg gaaattcaca agtgttacca
     2401 cgagattata ctagaagaaa tgaaatcgag ctggtggtaa aagaaatggc ggaacaagta
     2461 gcgatacgca ttaggcagca taactgtaaa acaggttgtg tccatttaca cattggcacg
     2521 tcgatcttag aaacgagacc agggttttca caccagatga agatccctat cacagataat
     2581 acaaaggaat tgcagaatta ttgtcttttc ttgtttgata agtattatga aggacaagaa
     2641 gtaaggcacg ttggaataac ctatagcaag cttgtgtaca ccgattcgct tcagctggat
     2701 ttatttagtg atccacaaaa gcaaattaac gaagaaaatt tagataaaat tattgacaag
     2761 attcggcaaa aatatggttt tacgtcgatt gtacatgctt cttcaatgtt agaaagcgct
     2821 agaagcatta ctagaagcac acttgttggt ggtcatgcgg gcggaaatgg gggaattaaa
     2881 aatgattgat tacaatgatc gtggacgttt aaagtgggca gggttttatt tatctgatca
     2941 tactgaagaa attgatgccg acaatgaaca acgaaccagt caaaatttag caaaagaaca
     3001 aatgacgact gaagagattg cggaagtatt gaacgctgca gtcataaaaa atagatcagt
     3061 atctattcaa aaagaagaac gaaacgctga ag
//
LOCUS       DARPZF010000126         2932 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.133, whole genome shotgun sequence.
ACCESSION   DARPZF010000126 DARPZF010000000
VERSION     DARPZF010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2932
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.133"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            4..963
                     /locus_tag="SLE65_002849"
     CDS             4..963
                     /locus_tag="SLE65_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HEI8450074.1"
                     /translation="MNGFAYTINNEFNLGANEGSSQVANNQYILLHETANETATGRNE
                     AQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIELQHTHDKAT
                     FEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEM
                     GVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNYAHIDQFGEIEN
                     ANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRSDVNQAYNTSGNVGYHVSF
                     NMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
     gene            1152..1225
                     /locus_tag="SLE65_002850"
     tRNA            1152..1225
                     /locus_tag="SLE65_002850"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1186..1188,aa:Ile,seq:cat)
     gene            complement(1740..2039)
                     /locus_tag="SLE65_002851"
     CDS             complement(1740..2039)
                     /locus_tag="SLE65_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450075.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2045..2275)
                     /locus_tag="SLE65_002852"
     CDS             complement(2045..2275)
                     /locus_tag="SLE65_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450076.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(2525..2725)
                     /locus_tag="SLE65_002853"
     CDS             complement(2525..2725)
                     /locus_tag="SLE65_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEI8450077.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT         1000 a          499 c          503 g          930 t
ORIGIN      
        1 ccaattaacg gatttgccta tactatcaac aatgaattta atttgggcgc aaatgaaggt
       61 agctcacaag tagcaaataa tcagtatatt ttactgcatg aaacggctaa tgaaacagca
      121 acaggacgca atgaagcgca gtatatgcaa cgttcatgga ctagcgctta tactgcttat
      181 attgtgggag acggcggaat tgtttatcaa gtcggtcaac ctggttatgt acagtacggt
      241 gctggttcgt atgctaatgc caacagtcct gtgcagattg agttacaaca cacacatgat
      301 aaagcaacgt ttgagaaaaa ctacaaggca tacgttgaat tggctagaga ttcagcaatg
      361 aaatatggta ttccattaac gttggacact ccttataacc aaccgggaat caaatcgcat
      421 ttatgggtaa cacaaaacat ctggggcgat catacagatc cttacggtta tctttctgaa
      481 atgggcgtaa gtaaagaaaa attagcatat gatttagctc atggatttac cgatgaaaat
      541 ccaacaactt ctgaaaacaa gcctgtcatt gatccaacac gagctggtgc agctaatcct
      601 acactgacag atggaacgaa ttacgcccac attgatcagt ttggagaaat cgaaaatgca
      661 aatttgcatg tagctggatg gcacattgct aactataaat acgagtatat cttcattatg
      721 gattacaata ctgggaaaga attagctcga gtaagagctg atggaattta tagatcagat
      781 gtaaatcaag cttataatac ttctggaaat gttggctatc atgtatcttt taacatgcgt
      841 aacttcccta ataagaaagt ctatgtcatg atgcgggcaa cgaatgatcc agagggaaac
      901 actaaaggcg gtgcgcaaga tttccatgac aaacgttggt atttaaatat tcctaaacga
      961 taaaaatagc tcctcgttga ggagcattac ataactatat tgacaactat aaaaatcatt
     1021 cgataaaata gtgatgttat cgcatatctt cactatcacc cataatagtc acactccaag
     1081 ctatgcgata acaggtttgt tgccacacat tctactggtt gattgtttat ggctttatgt
     1141 ggcaacaacc agtaccctta gctcagttgg tcagagcaga cggctcataa ccgtccggtc
     1201 gtaggttcga gtcctacagg gtacattaac gtagccattt gaatcgttct gtgttagaat
     1261 tttttgaaga gtattataca agctaaagct tttcttcatt gccactcaaa tgagtggctt
     1321 ttttatgtat ccttttatgg attaatgaaa ggatgtttca catagttata tttctgtata
     1381 tttgaaaagt tttactttga tttttaaata gaaagacatt tgggttatat tgtgagataa
     1441 taataaagaa gagtttaaag cgttccccaa aaaccactgc cccataagtg tgttacgctt
     1501 taaactcttt tatatttgaa gccattaaaa agcataccat atttttgaaa aaaagtgaga
     1561 aaaaaggctt ataattggag tggtagttaa ttagtgactt atttttgatt ttatagcact
     1621 gatactataa aatatagata tcatcatatt acacaatctt aatactaact taaaaaatat
     1681 ctcctttcat aagtatggtg ataaaatccg ttccgggcta cctttttagg tagcctactt
     1741 taatctttgt atctttctgg atcaacgaaa gtatacttta tatagtcata acgccgatga
     1801 tcgcttcgag cgtctagcac atcagtcacg atatcaaaca aaaaatatac gtctttcttc
     1861 attctagttt tcgcagcagg gattttaaag tagttcttat tagaatagta gagattaatt
     1921 aataagctat cttcgattgc taaaaagaaa acttctgaat cccacacctt ataaaaatct
     1981 ttgacaaatc tattcgaagg atcaaattta aaccataatt gcgtctcatt aaaaagcata
     2041 accattactc cgatctattt ttaaacttag tctctacctc taatatatat cgagttttta
     2101 ttttgccttc agagaatact gtttcttttt ttgcagttac aggttgttta ttttcggaaa
     2161 aagctaatat agctaaaatt gaaacatcca tctggaattt gtctttttcg ttgctttgct
     2221 cataaaaatc tgcatattca tcactaatat tttttctaat aaattcttcc atcataaaga
     2281 tcacctcgaa aagagtatac gaacaaacgt tctttttgta aaggtggaat ttattatact
     2341 aaataaatag gtgaacaagt acttgtgcca aattatgtgc caaaaaaaat cgaatttaat
     2401 aaaacacaaa caaaaagaaa tcctattatg ataacatttc ttataataac aaacacaaca
     2461 gaagacgtgt aatagttagt caggaacgta caaataaccc ctgtatcctt tgcggtacag
     2521 ggggttattt tgtataagta gacattgtag tttctaaact gctatgtcct aaacgtttcg
     2581 atacgctaag tatatttact ccttgataaa gtaaaataga tgcatgcgta tgtcttagtc
     2641 catcaataaa cagtcgaaga gaaaataggg aaaaattgat tactaaagaa aaacttacta
     2701 ggtcgacggt gtagttgatt ttcatacttc aatagattcg aattaaacga tttcgattgg
     2761 cttataccag tcctatccaa cgaaagatat atcgttctta actctagcgg tataacttga
     2821 agctttacgt aaagccaatg ggaatgaact ggagatgact ttttattatt tttagtaata
     2881 gctgatgggt taatacttac aactttcctt ttcaaagtac catataaaaa aa
//
LOCUS       DARPZF010000127         2861 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.134, whole genome shotgun sequence.
ACCESSION   DARPZF010000127 DARPZF010000000
VERSION     DARPZF010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2861
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.134"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            4..2376
                     /locus_tag="SLE65_002854"
     CDS             4..2376
                     /locus_tag="SLE65_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450078.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKDYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQTVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..>2861
                     /locus_tag="SLE65_002855"
     CDS             2437..>2861
                     /locus_tag="SLE65_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450079.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYA"
BASE COUNT         1144 a          455 c          620 g          642 t
ORIGIN      
        1 gacatggcag aagaaaaaga accactagac aatagtcgct tgggaaaatc caaaagaaaa
       61 ttagtacgat tgcaaaatga attaaacgaa caaattgaga agatgtttga acaccagaga
      121 aagaccaacg gtcagccaat gaacgataag agaaatgggc attcttggtt taggcaacaa
      181 gaacgtttag aaaacaaagt gcatagtctg agagaagaga tcaagcaaca agaaaaacag
      241 gtagaaaaac ttgaaagaca agaagagcta aaggaaatgg gctataacaa gtacggcggc
      301 ctggatatga caatcgaaaa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcga ctttttcagc cgctacgatc cgaaaatacc aacggaaatt ggaaacatta
      421 gaacagctga aagaaagatc agaaaaagga aaagaaaatc ttcttcctga agtacaagca
      481 attattgaca gcggacgagt gacgcaatgg aaaaaaaatc caaccattta ttttttgaaa
      541 gactatcgaa aagttgcttt agaactgaat gaaaacgggg gatttgagga atcaaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctgcg
      661 ccaactgatt ctttgaagga gaaagaaaac gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt agaattgatc
      781 gatcaactca aaacgttgga taaccaatac gccgcagaag caggttatta taaattctat
      841 tttgaagaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaacccat ctatttagag ttagcaaaat tgtgcgaaca agtacctgaa
      961 aaggaacaaa aacaaacggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taagcaagaa
     1081 gtcaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgaa
     1141 gacgtgaaag aacttttgaa ttttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc tgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaaggat tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctacacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
     1501 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
     1561 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacggggg gcgtatgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac ttcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagcg
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tgtagaaacg gcagagaata agaatattgt gcccgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtgat tttaaaagga
     2221 aaaagttatg gaaaagagat tcaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 ccattccgat tttcacttga aacagtgtca gaagtggcca aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgc gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt ttgaaaatga ccgaaaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagacta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac tctaagcaac aatttaaagc agccacagat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtagaaa atcttcattt tgagacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg c
//
LOCUS       DARPZF010000128         2856 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.135, whole genome shotgun sequence.
ACCESSION   DARPZF010000128 DARPZF010000000
VERSION     DARPZF010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.135"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            156..506
                     /locus_tag="SLE65_002856"
     CDS             156..506
                     /locus_tag="SLE65_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8450080.1"
                     /translation="MSRLIIQTAFYKAIIPENLDEVKLYLWEDNGEIVGFSGVSAEEL
                     VMLFLDPDFIGKRYGSQILIELIETEDIKRIDVNSQNKYAKHFYLSHGFEIESEEDLD
                     GFGKPYPITHLVKK"
     gene            920..1738
                     /locus_tag="SLE65_002857"
     CDS             920..1738
                     /locus_tag="SLE65_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEI8450081.1"
                     /translation="MNKNPHNLKLVAVDMDGTFARTDYTYDIPRFKAVLSRMKAVDCQ
                     FVVASGNQYYQLRSLFPNYYDELSFVAENGAFVKDKTEVLFSADMPRKAIEVVLDLCK
                     DYPEVKNVMCGLNSAYCERGKVSQAFFDLTNIYYHRLEWVADFAEVQDKILKFAPTMP
                     VEKTEFYVELFREKLAGLLVPTSSGHGSVDLILSECHKTFGLKMLVERLGINPDQCVA
                     FGDGGNDIEMLEYCGLSYEMDNATEAVKQVAKHQCPSNDEDGVLVTLDRLFPNT"
     gene            complement(1811..2170)
                     /locus_tag="SLE65_002858"
     CDS             complement(1811..2170)
                     /locus_tag="SLE65_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HEI8450082.1"
                     /translation="MSDNLFLEVQPEVFKQVPRLKDGFLLTLNDGSNQFSSAEGCCMI
                     GDHFLLVSTQHYIPAYDLTIPCEEATVKTSEYDTTFINGHLVLEVTPSNQTIRLKNES
                     GILDSNVQVYFDSSDAS"
BASE COUNT          972 a          402 c          508 g          974 t
ORIGIN      
        1 ttcgcaacga tggcaaccgg agtttcttga tgaaaatatg cttctatcat tacaagctcg
       61 tttggtgtaa gatgggtata agtcatttat gttcactctc cttgtatgct ttagcgggta
      121 ttacaatttg agtgtaacat aaatggcttt tttatttgtc tcgcttaatt atacaaacgg
      181 cgttttataa agcaatcatt cctgagaact tagatgaggt taaactttat ttatgggaag
      241 ataacggaga aattgtcggt tttagtggtg taagtgcaga agaattagtt atgctatttc
      301 ttgatccaga ttttattggt aagcgatatg gtagtcaaat attaattgag ctgattgaaa
      361 ctgaagatat aaaaagaatt gatgttaata gtcaaaataa atatgcaaaa catttttatt
      421 taagccatgg atttgaaatt gaatctgaag aagacttaga tggttttggt aaaccatacc
      481 ctataacgca tttagtaaaa aaataattca tgaatggttt attacctgat tgaacatgaa
      541 taaaagtaat atttttattt tgatggccta tttctaggtt atgaattatc cagatcaaat
      601 ttgtgtatta cattcagtaa taaggtgctt atcttaggat caacttatga tactagctga
      661 ccaaggatgt accagttata gaaaatcagt taaagtaaaa atgataaaaa tcttatgtca
      721 acactgattt aggctgacct gtgggttagg agaaagacag gtcggtagct tttaatacaa
      781 aaaatggctt gtatgtatct agatagttaa ctgaaattag aaatgttctt atttttaacg
      841 gagtaagaaa aataggctgc tttaggtctg aatacttttt caatataatg aagatatcaa
      901 aggcgacagg agtgttttta tgaataagaa tcctcataat ctaaagttgg tagcagtaga
      961 tatggatgga acatttgctc gtactgatta cacatacgat atcccaaggt tcaaggctgt
     1021 tttatcgcga atgaaagctg ttgattgtca atttgttgtt gcaagtggaa atcaatacta
     1081 ccaattgaga tcgttatttc caaattatta tgatgaatta agttttgttg ctgaaaatgg
     1141 tgcttttgtt aaagataaaa cagaggtact attttcagcc gatatgccta gaaaagcgat
     1201 cgaggtggtc cttgatttat gtaaagacta tcctgaagta aaaaatgtga tgtgtggtct
     1261 gaatagtgcc tactgtgaaa gaggaaaggt gagtcaagca ttttttgatc taaccaatat
     1321 ctattaccat agattagaat gggtagctga ttttgcagaa gttcaagata aaattttaaa
     1381 atttgctccg actatgcctg ttgaaaaaac cgaattttac gttgaattgt tccgtgaaaa
     1441 attagccggg ctattagtac ctaccagtag tggtcatggt tctgtagact tgattctttc
     1501 tgagtgccat aaaactttcg gcttgaaaat gttagttgag cgcttgggga ttaatcctga
     1561 ccagtgcgtt gcttttggag atgggggcaa tgacattgag atgttggagt attgtggtct
     1621 gagttatgaa atggataatg caacggaagc tgttaagcaa gttgctaagc atcaatgtcc
     1681 ttcaaatgac gaagacggtg ttttagtgac gctcgatcga ttgttcccta acacgtaaac
     1741 actaggtaat tcatcaaaaa acctcgatat aagaaatatt cgaggtttta aaactatatt
     1801 tagaacagat ttacgaagcg tctgatgagt caaaatagac ttggacattg ctatctaaaa
     1861 taccactttc attctttaaa cgaattgttt gatttgatgg agttacctct aatactaaat
     1921 gcccattaat aaaggtagta tcgtattcag atgttttaac tgttgcttct tcgcaaggta
     1981 ttgttaaatc atatgctgga atataatgtt gtgtggaaac taataaaaaa tgatcaccaa
     2041 tcatacagca tccctctgct gaagaaaatt gattagagcc atcatttaaa gttaacaaga
     2101 atccatcctt taaacgaggt acttgcttaa atacttctgg ttgtacttct aaaaataaat
     2161 tatcgctcat tttcacgacc accatcgact tccacagttg aaattgacat tttatttaac
     2221 acacctattc ccccttaact ataactcaat tctatataaa aaatattcta ttctcaaata
     2281 attgaacttt tcaaatcgcc aatttacttc ggctttatca gagctcattc atatcaagag
     2341 cgattaacgc tgtaaaaatt aaaccgaaga tctgataaat tttctctatt ttctacaata
     2401 tttaaaacgc ttccttagtc tattatatat ctatttctct taggagtatg tttagatgtt
     2461 tgaataatag ttgcccaact ttaaaggtta ttcttataat attttacttc attttccaat
     2521 agaaaattca aaggattact ggtttttcta aaatagttta gtttaaatac ataagtatcc
     2581 tccgacactg tattagttca taatcatcta aatacaaaat tttcaaataa aaatatttca
     2641 agctctatcg ttgacgaatg taaacgatac ttataaagta atagaaattg attacatttg
     2701 taaacttaaa atggttaatt tatctcacat aaaactaaga ataaaataat gattaaaagt
     2761 ggttagtttt tatacgattt agcctatcgg taaaaatgaa ttagagagtg taaaatattt
     2821 tgtgtaaatg aaaaaatcca tacaaaaaag gaagtc
//
LOCUS       DARPZF010000129         2641 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.136, whole genome shotgun sequence.
ACCESSION   DARPZF010000129 DARPZF010000000
VERSION     DARPZF010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2641
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.136"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            112..1311
                     /locus_tag="SLE65_002859"
     CDS             112..1311
                     /locus_tag="SLE65_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEI8450083.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(1338..2606)
                     /locus_tag="SLE65_002860"
     CDS             complement(1338..2606)
                     /locus_tag="SLE65_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HEI8450084.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
BASE COUNT          792 a          573 c          469 g          807 t
ORIGIN      
        1 ataagaaaaa catctttcca tcggaaagat gtttttttgc tttttctagt ttaaataaca
       61 gcttttttca tctattttcg ttatactgta taagaaaaag gagttgaatt tatgaatcta
      121 accagagatc tgatcttttt agttctctat cttattgggg tattctctat cgtttattgg
      181 cgaaaacaga agaaggatcc ttccttgttc ttttacggca gtacgtggac atttacggta
      241 atcttaactt attttgtcgt gttggaaatt ttttattcga ccttttattt tttgattcca
      301 ttgttgttct ttagtatctt tgctttttct tatttcacag aaaaacgaag gctactgaat
      361 ggtcttttat tcaatgtttt actcatcagt ttcggcatct acttgtttgt cttgctgtat
      421 gaaacgcaaa atatttttct tggcggactg atcgccttga tcacgattcc attgctactt
      481 gtccttttat ttggtattta tggattgatt gtttttcttt tttggaacgg ggtcacagtt
      541 ttacgtagag aatcgcattc attagctaat cttttaacgt tgatactagc catttttctt
      601 acactgtttc ttgtttttga ctttttcttg ttaaaatatt tgccgcaatg gataaatgct
      661 ttgtttttct gcgttcccct gatcttgatc tatctattta tcgtattcta caactttttg
      721 actgtctcat tcttgtatca gttcaaccgg cctcgataca atcaagactt catcgttgtg
      781 ttaggcgctg gattgatcaa tggagaaaca gtttctcctc ttctagccaa gcgaatcaat
      841 aaggcaattg ctttttatcg ggctcaaagc cgtgctacat taaatccgcc catcttattg
      901 atgtctggcg ggcaaggagc agacgaaaaa gtaccagagg ccattgcgat gaaacaatat
      961 gccatggaac aaggaatccc tgaaagagac attcttgtcg aaaccaattc gacaaccact
     1021 ttggaaaaca tgctctattc aaaggaaatc atggatcagc aaatgaaagg gccataccgc
     1081 gcgatcttta gttccaacaa ttaccacatt tttagagccg gtctttatgc gcggcaagcc
     1141 aaattgaaag caaatggtat tggtgcaaaa acagctttct actacttgcc taatgcgttt
     1201 ttaagagaat acctcgccat cttgatgatg aacaaaaaaa gacatatgat catttgcgga
     1261 ttgcttttcg caggctccgc attcttatcg ctgattactt tacttttcta aaaaaacaag
     1321 gtgtgacaaa acatatgtca caccttgttt ttttctttca ttctcttaac tattggcaaa
     1381 aagagtatcc cttttttgac cgctacttgc tgagcagaat aaataccgct gttgcctgaa
     1441 cacataaagc tgatcaagca gatcataaag aagtatactg ccgcttgtga accgaacaat
     1501 tcgatcccca tcacaaagca ggcaatcggt gtatttgtcg caccagaaaa tactccgata
     1561 aagcccaatc ctgcaagaaa aggaacagaa acatggagca aaggcgctag tgctgcacca
     1621 agcgttgcac caatttcaaa caatggtgtc acttctcccc cttgatatcc cgcgcctaaa
     1681 gacaaaactg tgaagaataa cttcccaata aaatcataga catgtgcctg tccattaaat
     1741 gattcttgaa gtaacggaag actcaatccg agataacgtt gtgtttgcaa aatcaatgct
     1801 gctgccacaa ctacagctcc acctatcgta tttcgacaaa caggatgagg aatccattgt
     1861 gcatatcgcg cttttaaaaa gacgatcgaa cggctgaata cccaaccaat caaaccaaaa
     1921 gcaatcccag caacaaaaac tttgaagaac agcaacatac tccattcagg aatcacaccc
     1981 atttggtaat gtagatgaga aacaccatag ctttctgtca tgaaatttgc aaacagtgca
     2041 gcaaagaagc tagggaagat cgcttctgtt cggactttcc cgattgccaa cacttctaat
     2101 ccaaataatg ttccagctaa aggtgtgcca aatacagaac taaaacccgc actgattcca
     2161 ctgataatca agatttcccg ttctgattta tccaatcgga acaaacgtgc cgtattatct
     2221 gctaacgctc cccccatttg gactgctgtt ccttcacggc caacagatcc cccaaataaa
     2281 tgggtagtta tggttccaaa cagtgtaagt ggaataagcc gcaacgggat tttttcttct
     2341 ccaccatttc cttgatcgat cactaagttg tttccacgac tagaaagtcc gccgtgatac
     2401 gcatagagat aagcaaaaag cgcaccacta actggtagta gacaaaggag ccaaggatgt
     2461 gatagtcgga tatctgtcac aactgtcagg ctatttaaga aaaaagcaga caagctcccc
     2521 atgaatatac cgagaatcgc tgtgatcacc agccacttca gcatatacac taaaatgcgt
     2581 actggactcg gtaattgttt ttccataaaa aattcctcct caataaaaaa acgcctacta
     2641 a
//
LOCUS       DARPZF010000130         2634 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.137, whole genome shotgun sequence.
ACCESSION   DARPZF010000130 DARPZF010000000
VERSION     DARPZF010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2634
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.137"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            5..1150
                     /locus_tag="SLE65_002861"
     CDS             5..1150
                     /locus_tag="SLE65_002861"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEI8450085.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            1321..1779
                     /locus_tag="SLE65_002862"
     CDS             1321..1779
                     /locus_tag="SLE65_002862"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEI8450086.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1938..2408
                     /locus_tag="SLE65_002863"
     CDS             1938..2408
                     /locus_tag="SLE65_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEI8450087.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(2461..2576)
                     /gene="rrf"
                     /locus_tag="SLE65_002864"
     rRNA            complement(2461..2576)
                     /gene="rrf"
                     /locus_tag="SLE65_002864"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          863 a          504 c          496 g          771 t
ORIGIN      
        1 aaacatgcac attcaaacaa aattgatcca cggaggcatc agtgaagatc ccacaacagg
       61 agctgtcagt gtacctattt atcaaacatc cacttatcgg caagatggcg tcggccagcc
      121 taaacaatat gaatattcaa gatctggtaa tcctactcgt tttgcattgg aagaactgat
      181 tgctgatttg gaaggcggtg ttcgaggatt cgctttttct tctggtcttt ctgggattca
      241 tgccgttttt tctctttttc aagctggcga tcatatctta ttaggagatg atgtctatgg
      301 aggaacattc cgtctatttg acaaagttct tactaaaaat ggtctcgagt acacgatcat
      361 agatacgagt aatcttgata aaatagaaca atccatcaaa cccaatacaa aagcacttta
      421 tcttgaaaca cctagcaatc cgcttctaaa gattactgat ttagaaaaaa gtgccactct
      481 ggctcatcaa catggattga tagttattgc tgacaataca tttgctactc cttattttca
      541 aagaccttta gatctcggtt ctgatatcgt tgtccatagc ggtaccaaat atctaggcgg
      601 acacagcgat gtagtagctg gtttagtgac ttctaaccat aaagatctag ccgatcagat
      661 cggattttac caaaatgcta tcggagccgt acttggtccc caagatagct ggttacttca
      721 gcgcggaatc aagacactaa gtgttcgtat ggaggaacat caaaaaaatg cttttgtggt
      781 agctgatttt ctattttctc atccagcagt agaaaaggtc tactatccag gattacccga
      841 tcatgaactc catggagttg ctaagcagca gatgagcggc tttagcggaa tgatttcttt
      901 tactttaaaa aatgaagaat ctgctattcc atttgttgaa tcactccaac tatttacttt
      961 agcagaaagt ttaggtggcg tagaaagttt agtggaaatt ccttctgtca tgactcatgc
     1021 gtctattcca aaagaaaaac gagaagaggc tggcataaag gacggcttga tccgtctttc
     1081 tgtaggaatt gagtatggtc aggatctcat aaacgattta gctcaggcat ttgacagaat
     1141 caagaactag aagtcccaat aaacgactta gcagaaaaat ctaaaaaata tttcagattg
     1201 ctacaccttg gaaacgataa gtgttagaat caagtagaaa gacgtttttg taaatttcac
     1261 taaataattc tttagtgaaa agcatcaaaa cgaatgaaca aacagatagg agtcttacaa
     1321 atgagaatga atgtcgaaag ttttaatctt gaccatacaa aagtcaaagc accttatgta
     1381 cgtgtagctg atcgaaaaac gggtgcgcat ggcgatgtca tcattaaata cgacgtccgc
     1441 tttaaacaac caaataaaga acacatggac atgccaagtc tacattcact tgagcacttg
     1501 actgccgaac taatccgcaa tcacgcagat tacatcgtag actggtctcc aatgggatgc
     1561 caaacaggct tttacttgac tgtattgaat catgaaagct acgaagacat tttagatgtt
     1621 cttgaagcaa caatgaaaga tgttcttgaa gctactgaag tacctgcaag caatgaaaca
     1681 caatgtggct gggctgccag ccatacacta gaaggtgcac aagctttggc tcgtgaattt
     1741 ttagcaaaac gcgatgaatg gtctgaagta gaagcatagt ttctaaaaga acgtaaagat
     1801 gagaagcaat atagctatct tatcttcgta ttttattaaa tatttattgt ctgaaaagag
     1861 ttctaaacgg gaaaacaaat agctagtttt cagtttagcg ctctttttat tatataaaat
     1921 agaaaggaga aaactttatg tctatttata attttgaaac tactttagaa gacggcactg
     1981 tctattcatt gaaaaaatat gcaggcaaac cgataatcat tgttaacact gcaacaaaat
     2041 gcggtctagc acctcaattt aaacaattag aagaacttta ccaagcttat cagacacaag
     2101 gtctggttat cttaggcttt ccttccaatc aatttaaaca agagctagat tcagcgactg
     2161 aagcagcaga agcttgtaaa accacttatg gcgttacctt ccctatgcat caattgattg
     2221 acgtaaatgg agaaaataca gatcctcttt ttacttatct taaaaatgaa gctcctggta
     2281 ctgtcactaa agcaataaaa tggaatttta ctaaattttt gattgataga aatggcaaag
     2341 taatcgaacg atttgcacca caaacttctc cattgaaaat gaccgctgca attgaatccg
     2401 ttctttaact taataaaaat aaaaaaagat gaactatttc tagttcatct ttttgccttt
     2461 gcgtggcgac gtcctactct cacaaggggc aacccctcac tacaatcggc gctaagaagc
     2521 ttaacttctg tgttcggcat ggttacaggt gtatccttct cgctatcgcc accacactgt
     2581 ggtgttatct tttattgagt aaattttgtt cactcaaaac tggatttgaa gtca
//
LOCUS       DARPZF010000131         2628 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.138, whole genome shotgun sequence.
ACCESSION   DARPZF010000131 DARPZF010000000
VERSION     DARPZF010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2628
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.138"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            1173..1727
                     /locus_tag="SLE65_002865"
     CDS             1173..1727
                     /locus_tag="SLE65_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEI8450088.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
     gene            1981..2292
                     /locus_tag="SLE65_002866"
                     /pseudo
     CDS             1981..2292
                     /locus_tag="SLE65_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2403..>2628
                     /locus_tag="SLE65_002867"
     CDS             2403..>2628
                     /locus_tag="SLE65_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HEI8450089.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIACVIWGIINGYTSQRATYRAVC"
BASE COUNT         1015 a          309 c          414 g          890 t
ORIGIN      
        1 ggaaaacgta gacgtaattt tctacgtttt ccttttcata tatattaaat attacggaaa
       61 tttatataaa ctaatttagt gttttgtttg taattcctaa ttttgctcca cttttagata
      121 atttttaggt ctatttaact catcagacat tctatgctca ttttctccaa atttgtttca
      181 actctttcgt acttaatttt gcgtatttga aaattcttct tttagagtac ttttattacg
      241 atactagtat gatatatatc tatagcaaac agttaaaatc ttcctaaaat aagcgaatag
      301 cattcctaaa acctataaaa tttttagatg aagcgacaag tggacaatta ataaactact
      361 tgaacatgaa attatggatc acctttcaaa tttagaaaat ggaattctta tacttattgc
      421 gcaacattta ttgattgcaa aattatgtga caaaaagaac tagtagaaga aggaataatg
      481 gcttgataat aaagtactac ctattaaagg tagtacttta tttaatttag tataaattaa
      541 catactacta tattttaagt ttcatattat ataaattaat aatatactac cattttttgg
      601 tagtataatt taaaggtaat aagttattct tttattacta tgtttgggtt ttatagcaag
      661 gaaagtttaa taagagtttg gacctagcaa acaatattaa tgaggtcatt aaatcttatt
      721 atctttagtg atataacgaa atatctacac agacaaaatt atgatcttgc gtaaagttat
      781 aaaatattaa taaaaatatt ttattaatga aaagcttggt agcacggtta ttcatatgct
      841 aatttatttc actttatagt aaggggagtt cttagtatat tgtccaaatt taaatttcat
      901 ataatttaat tatgtaaatt agctattcta agaacttcta cggataactg cccgtctaaa
      961 atttaattaa gagcttagaa tcttcatata agtaaggtta atttttttgt acaaaatagt
     1021 cggaatattc tgagttactg aaatgatata aaatcataaa ctaaacccct tgattttctt
     1081 cacttttaac agagtatata tataagttca tgattatggt aaaatatata tataatcatg
     1141 aactcagaat atttttaaga agggaaacaa tagtgagcta taatgtacaa ccgttaagga
     1201 caaatgaaga gatacaagat tttcagtttt ggctaagaag aacaagtaat ccagaaagag
     1261 atagtttttt atttttgttt ggaatcaata atgggttacg tatgtcagat attataggat
     1321 taaaagttgg agacatacga ggtaaaagta agcctattat tgttgaacat aaaacaggta
     1381 agcgaaaacc gatttttata gataatttga gagaagagat tttattatat actgaaggta
     1441 aagaagaaaa tgattggtta tttccaagtc ggcaacaagg tcgacatata acaagggatc
     1501 gtgtctatca gatatatgca gatatagcag aaaaattagg aagagatgat ataggaacac
     1561 atacattaag aaaaactttt gggtatcact actacaagaa aactagagac attgctacct
     1621 taatgtttat ttttaatcat agctcgcaag caattacaaa aaggtacatt ggtataactg
     1681 aagatgaaat aggggcatcg ttacgtggtt ttaaattggg aggctaattg agatattagg
     1741 atatattttt tgtgtataat gaaaacttag aaggtgagat taatgaagat aactgaattt
     1801 tcggaagtat ttaaaacgtt tagtaacatt tacaatagaa taccagagat agaacaaaat
     1861 gttgtagttg ataatgatta ttatatagag aatgatttta ataaaccaag aaaatatgac
     1921 aacctataca attttataca caatagaaca acaataaata acaacagtaa cactcgagtt
     1981 ttgattaatt cagcatattt tcatattaaa tatttaaaga aatatgagta tgaagaagtt
     2041 gtattagatt atgggctaaa tagacagtca tttttaattt atgcaataaa taacggaaat
     2101 ttgccaagca ataaaaagaa cataattatt gaaacatatg cctatctgga ggggggatct
     2161 aaaaaactaa ttaagtcatg taatatagag tatcaattat cagtaggaga aattaaatgt
     2221 gttttcgaag aagatttaga acttgactta aaaaaaattt ttgccagcat tcatgattat
     2281 ataggtttga tacccgtggt gctagttaat tttttcctag aggaaaatgt ctaaacatgt
     2341 tggtaaatca acaaaaaaac gcatatagta gtctcaaaac tcccaagaaa tgaggactac
     2401 atatgcgttc atcaaaatat actgaacatt atacagatac ttttataaca ttcaaggaaa
     2461 ttatgagaac tgtttctaac atataccaca attgtgtacc agataagatt aaaaaccgaa
     2521 gaaatactga tcaactgaag caacgcgata cagtgattat tgcttgtgtt atatggggca
     2581 taattaatgg ctatactagc caaagagcca cgtatagagc ggtttgtt
//
LOCUS       DARPZF010000132         2618 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.139, whole genome shotgun sequence.
ACCESSION   DARPZF010000132 DARPZF010000000
VERSION     DARPZF010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2618
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.139"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(493..1785)
                     /locus_tag="SLE65_002868"
     CDS             complement(493..1785)
                     /locus_tag="SLE65_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEI8450090.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(2059..2319)
                     /locus_tag="SLE65_002869"
     CDS             complement(2059..2319)
                     /locus_tag="SLE65_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450091.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          886 a          483 c          398 g          851 t
ORIGIN      
        1 ttatattata aattcacatg attatcgaat tttattaagt tagtttttct tgtaaatctc
       61 tgttcccaat gaaactcgag acacttattt taaagaggaa acaatgtggt atttaaatag
      121 ccctcttgta tgggctactc tgtgatactt attagccatt aaactatttt acccacatag
      181 catatatttt gaaatcgttc attccgtaaa ttcaactaaa tatgcctaaa aaaataaaaa
      241 atctaagata gaataagatt tattcagtct tagatggatt tatagcaact ttttcgtaac
      301 aactttaaaa aatacgaaaa gaaagagctg ttttactctg actacgttgc taaattgtcg
      361 tttaatcatt catttaaacc aaatcttttt ttatagaatt cgttttaatc ctcctgaatc
      421 caaaaactat gaaaaccgta attaaatagt taagagtttt taaccaccat aattctctcg
      481 gctattttga aatcagataa attttgatcg gacacatagt tgaataaacc taccgttgtt
      541 acggaaggta aatcgcatac ttttcattct agaggagaag gtctcgttga tcattaactg
      601 attaagcacc atagcccagt tttgaattcg accacctgac cacttcgcgt gtaattcttt
      661 cgtgcgtaaa taaagtagtt ttaggagtgc attctcatta gagaacgctc ctttttttgt
      721 gacttttctg aagctggagt ggacactttc aaccgcattg gtagtgtaca taatttttcg
      781 aatggcacta ccataatcaa atagttgttc aacatgtgca aagttccgtt tccagacatc
      841 tacagcacca gaataatgag accaccgatt ttgaaaactg tcaaaagcag catgtgcagc
      901 gtttagagaa gaagcaccgt agaacttttt catatctcgg cagacttcct tatagtcctt
      961 acttggaata tagcgcaatg catttcgaac aagatgaaca atacagcgct gaacaattac
     1021 cgatggaaag atcgcttttg cgccttcttc gaggccagaa acaccgtcca tcgaaatgaa
     1081 aaagacatct tcgacaccac gtgctttcag ttcatcaaat acttgcatcc agcgattttt
     1141 agattctgtt tgatttaacc ataatcctaa aatctcctta tttcctttga gatcatagcc
     1201 aagaatggtg tatacagcat attctttggc ttcataattt tctcgtaaag taacatacat
     1261 acaatcaacg aatagaaagg cataacactt tgctaggggg cgggcttgcc attcttccaa
     1321 ttcaggaagg acagcgtcag tgatatctga aatcatttca tgggaaatat caaagccata
     1381 aatagcttcg acggttgcgg caatatctcg ttgactcatt cctcgtgcat acatggaaag
     1441 aaccttccct tcgatgtcgg agacatctcg ttttctctta ggaattaact ctggttcaaa
     1501 ggaagcttcc cggtctctag gaacatcaat agctacttca ccaaaactgg ttttaagcgt
     1561 tttagttcca tagccatttc gacggttatc gtgttcctta ggctctttag aatgggcatc
     1621 ataacctaaa tgattattca attctccttg aagcattttt tcaaaaaggg gcccaaacac
     1681 atctttcaaa gcatcttgca tgtcatcgac agattcaggt tgataggcat tcagaatgga
     1741 ttcagctaac ttttcggcat caggatttct tttctttcta gccatcgtgt aatcacctct
     1801 tgatcttatt gtagaaaaag aaaaaccgcg aagcaaccac ctgcctagga ttaatggtta
     1861 cttacacggt ttatattaca ctctcatcat taaaaaagta tctttcgata ttactaaaca
     1921 atgaaattat ctatttgaaa tttaaatctg ataatatatt gagtgttcca atgagggctt
     1981 tgatcctatt atccatatct ttttcagttt taatattgat acacattata agaaaaagaa
     2041 acttttggtt aatttatttc atcccagtgc aaaatataaa aaagtaaaat agaccatagg
     2101 caatagatta acaattaata taatacaagc aaatattcta ttcattgtat ttctgctttc
     2161 aaaaagttct aatattgaaa gtataattcc acaaatgcct ataataagta tgggaataag
     2221 attagaaaat aacaccccga gccaatctgt gaaaattact atatttacta atatccctat
     2281 taacatacct atcatattta ttaaatcaat ttttttcatt agatatttct cctttattaa
     2341 atctgaagta cttatattaa aataattcta aactatttac ctcaaaaagt gcaataaatt
     2401 atttctgaac aataaaatga tagtcaaaac aaaaaaatat tgttaatcgt tcagagccat
     2461 ccgagagtgt aaaatatttt gtgtaaatga aaaaatccat acaaaaaagg aaggcgcttc
     2521 tgtagaataa agttaacgac aaccaattca cagaaaagag gacttcccta tgaatgattt
     2581 tactacagaa attgtgcaaa ctctagtcac taaaggcg
//
LOCUS       DARPZF010000133         2482 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.140, whole genome shotgun sequence.
ACCESSION   DARPZF010000133 DARPZF010000000
VERSION     DARPZF010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2482
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.140"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(1013..1303)
                     /locus_tag="SLE65_002870"
     CDS             complement(1013..1303)
                     /locus_tag="SLE65_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450092.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1511..2202)
                     /locus_tag="SLE65_002871"
                     /pseudo
     CDS             complement(1511..2202)
                     /locus_tag="SLE65_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
BASE COUNT          733 a          458 c          348 g          943 t
ORIGIN      
        1 tacttgcaaa gtaatactac aattcctaac ataatcgtag aatttaataa tttccatagc
       61 ataaagtgtt tagaaaagaa cattaagaat agttctataa taattcttga actccatgtc
      121 ttataatgtt ctatcgaagc acccaaatag ccaagttcat ctaatctact tgcataaact
      181 acgtcatccg ctctcatagt cggcatatac atattaaaga gtaaaaagat accccaaatc
      241 cctattagta acaagatcag ttctttgtta ttcgttattt ttctattatg tttgttcatt
      301 tttatactcc ttcttatatt tcctaataga gtataacata gctttaagca ttacttaaag
      361 ataacttaaa agttatcttt taaatactta attgttaaat accttatttg atgcaaaaga
      421 aatctacgat agtcaacaaa aaaattttca ttatatccag aaaaattttt cttagttaag
      481 gacctatgga ttgcagtaat gcagaattcg tcgaataaac tgccaaagac atacaatcat
      541 attgctttta aaattgacga acaagatata gattcgtttg tctcaaaaat ccaaatgtta
      601 ggtttaactg tcgaaccagg acgttctcgt gtgaaaggcg aggcttcttc aatttacttt
      661 tacgactatg ataatcacct cttcgagtta cataccggta ctctccagga acgtttaaaa
      721 tcctacaatt ccactacctg agactagtaa tgactagtct ctttttatgg cctctgatcc
      781 ccccattgag cgaatactaa tagggcttcg aattgatctg ttcaatcttt aagcaatatc
      841 cctcaaatga gtttggaaag tttagtgatt catcacaaat acttaaatac atgtagttat
      901 atatagattg aggttcttgt gagcgtatgc tcgtgtgggt tcaaatccca tcgtctgcat
      961 ccatctttcc aaaacaagcg gctaggacat ttttgtctca gccgcttgtt ttctagttta
     1021 ttctttcatc ttgtcggacc ttttttcttg ggtatagact tttctcatat tctaccacaa
     1081 ttttgggttt ccctaacaca tgataggatc tcacaacaaa ttgctttcta ttattataat
     1141 aacctgtaac gactaacttc atcccttcgt ctacttcagc taggaagttc aaactatggg
     1201 aagcaatcaa acaattgacc ccatttaaac tgaaacggat caacggtctg gcactaactt
     1261 gcaaagtacg gatcttatct actgttccat attttttctc cataaccttc acctcaatac
     1321 cattatacga acatacattc cctttgtaaa gaagaaactc tgttttatct ttttgacttt
     1381 ttgtctatta cctttcttaa aatcatattg gcacttcctg cgaagatgaa ggacatgtac
     1441 taaaaaaaag aggcagcagt atagattact gttgcttctt tactaattta ggtttacttg
     1501 ttaagaaaga ttatttacgc aaatgttctt caacaatttg ctgagattta tcagctgtat
     1561 cttccacttc atcttttgct ttttctaact tttgaatata ttgtttcaag cttgagtttt
     1621 cagcagttgc ttcgtctaat ttcttttgtg tatctgttaa ctgatttcta catttgtttt
     1681 ttcttgtgtc agtgttgcga tttgttgatt caaaccattt acagtatttt gtaattctga
     1741 aagttttgct tgtgcttctt gtagtcttgc tgtccaatct gcattcagat gattgatttc
     1801 atcatttttt tggttgatct catctagttt gacattgatt tcattttgtt tgctttgtag
     1861 ttgtgcatcc ttgctgacta attgactttc taagttttgt ttttctgctg ccgattgatt
     1921 tttttggttt tctaattcat ttacttttgt ttggtattct tggacatctg cctttgaatc
     1981 ttgcaatgtc tgttcttttt gtgctagtcg agcggtaaga tctgtaatcg cttgctcttt
     2041 atctgtcaat gtatgatcaa gctgtgtcag attctcattg attgtatcaa tatctgtctc
     2101 tccaccccac aaaataattt catttgcgta ccgcgtgcct gtgtagccaa ttagacatag
     2161 aaatgcaacg acaatcccac cagtaataaa tttctttttc atttgcatag ctccttaatc
     2221 caatactttt acatgctaaa agtaagtgat ctcaaacaca atgtcaagcg tttttaaatt
     2281 acatatgtaa ttttaatata aatactatca aatactcatt taatcctcct tttttatcta
     2341 tttaaaaaat cttttttata gagaaaaatg caggttaata ctttcttaaa taaatattta
     2401 tggtgaacaa aaacaaaaaa gcaagtttta ttaaacgtaa cccttttcat ttcatagatt
     2461 actgtattta ttacaaaaaa cg
//
LOCUS       DARPZF010000134         2399 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.141, whole genome shotgun sequence.
ACCESSION   DARPZF010000134 DARPZF010000000
VERSION     DARPZF010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.141"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            206..2068
                     /locus_tag="SLE65_002872"
     CDS             206..2068
                     /locus_tag="SLE65_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEI8450093.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2068..>2399
                     /locus_tag="SLE65_002873"
     CDS             2068..>2399
                     /locus_tag="SLE65_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEI8450094.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          715 t
ORIGIN      
        1 aaaatttgaa aaagcgtttg attatttata ttacgactta gtgcaataaa aaacgctttt
       61 taacagtaca tgtagtcgtc tttataatag ataaactctg taatattagt taaaaagcta
      121 taagttgcac ttagttaagt gcaaacattt catattgtcg ttagtttaga aaacgcttat
      181 attagcaatg taaggagaga tgataatgca gcagctaaca aaaagagaaa ggcagctttt
      241 gatttacttg gtggaaatgt ctgaaccggt aacaatcaaa aagttggctg aaaaagaaaa
      301 tgttagtgtt cggacgataa aatacgatct agatgatata agagagtggc tgaatgagcg
      361 gaagcaagtc ctatatagca aacgtagtca gggaatttgg atgaatatta gtagctctga
      421 tcgaatcaaa ttaaaaagcg aattgatgga tgttaatcgt tttgaaatat ttgcagatca
      481 aagtctccga atcaaacgtt tactaattat gcttttagta acaaaagaag ctattactgg
      541 aatgaaaatg gccaacgcat tagatgtcag caaagatacg atcatgaatg atttagatgt
      601 gctggaaaat aattttctta aggaaggatt gaccttgaat cgtcaggcgc gaaagggttt
      661 ttggatcata ggagaagaac gtctagttcg attaacgatt gaagagattc ttcaaaaaga
      721 gttcacggat tatgacattt ataaattaat gtcattgtta ttgaatggcg gtgagactga
      781 atactttgaa atgtattctg ctactgctac acctatccaa gaggtattta atcaagtaat
      841 cattcgaatg cgacacttac tggaatttga aaatctagag aaactgaatt acgcggaatt
      901 actaaatatt ctgattcgag tgacaattgc taccgttcgc ttacgcaaag aggctacgat
      961 tggtcgttat caattggttg ctgaacaaga attagacaaa aacgatcttt cttatcgcgt
     1021 catgcagcag gtctttgatt attatcagtt gccactgttc gaggatgaat atcattatat
     1081 ctatagtgat acattcgaca cgattcacca gcaagacgtc atgaaactag ttgagaatgt
     1141 gatttataaa gtaagtaaag caatcaacca ttctttttat caagatccac aattgttgac
     1201 gaatctgtat gctcatttat ccatgcgatt atcgagaaag aaaaaatttg tcaatgaata
     1261 taatcctttt aaagaagata tcaagcagaa atacccggaa ttatttgatg cgatcaagca
     1321 agcagttcga caagaaataa gtgaacaaaa tattctgatc aatgattctt tcgtggcata
     1381 tattgcctta cactttttgg tttcctacga aagagaagaa gatctacgaa gcgttagagc
     1441 cgtctacatt tgttcaacag ggttgggtgt gactagtctg atcaagcaaa agatcaatga
     1501 agaattaaat aatatcacta tcgtggcatt tgcttcagta ttgaatgcgc aagaaatgat
     1561 tgctaccaaa gatcctgatt tggtgattag tatttttcca attaatggca tcgatcgtcc
     1621 tttcatcaaa gtccatccat tacccactga acaggacttg aaaaaaattc aacaaataat
     1681 aaaaaaaata cttgcttctt ccaatcagca ggaaaggcat aacttgaatc ttagagaaac
     1741 gtccatcaat aaagatactt tagaagactt tagcaaggaa ttgattttga aagcttatac
     1801 gatttatgaa cgtttacttg tcattttgga agcagaattg atccaagaat atcgagaagc
     1861 ttttttgctt catgtattct taatggttca tcgtatcaca tttgatcaac aatatatggc
     1921 agaaggtcgt caagtagacc agattatttt agacaaagga acactggtag gaaaaatcga
     1981 agcagttttt gcagaaaata atttaggaat caatcagtca gaaatcagtg cattattctc
     2041 atatataaaa gaaggagcgt caagttagtg aaaatgtcag acgaggcttt aaaaattatc
     2101 gaggaaagtc aaaatcggga aaagttaaaa caagtgattg atctaattga agagcgatta
     2161 gtagaacatg ctattgtacc aaccgagttg cagtggacca ttctaattaa tcacttgaat
     2221 gagatgctga aacgttctca aagaaaggaa acgattcccg tagtcgatcg ggatttgttc
     2281 aaagaagtat ccaaagaagc cataactatt tctgatgaaa tagttagaag tatcggtaat
     2341 ttaaccgatg atgaaatata tgttttgtcg attcattttg aaacagcaaa aaataatta
//
LOCUS       DARPZF010000135         2312 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.143, whole genome shotgun sequence.
ACCESSION   DARPZF010000135 DARPZF010000000
VERSION     DARPZF010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.143"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..731
                     /locus_tag="SLE65_002874"
     CDS             <1..731
                     /locus_tag="SLE65_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HEI8450095.1"
                     /translation="KLDSFIRNQLHYFVNQIEIFWKKSLSDNMCVSYEETSIFPKNQC
                     YLDKNIYSDLKWAEDIIGHFNSFFYSNQSPTFKHHHIKKNHCLPIWALFEEITFGSLT
                     TFINQLNTEYYNNWVMSCYDNPKYKKAIRSWANVIRAYRNKIAHHSRIYAFKVTDAPT
                     IIKNDSKSYFPENNLKETQKLYLYGGLYVIKHLLIYEDSMTQTLWNKFLIDLEKKIDK
                     IPSLEKSNYGFPENWRNKLKIMIV"
     gene            complement(1233..1649)
                     /locus_tag="SLE65_002875"
     CDS             complement(1233..1649)
                     /locus_tag="SLE65_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450096.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
     gene            complement(1651..1932)
                     /locus_tag="SLE65_002876"
     CDS             complement(1651..1932)
                     /locus_tag="SLE65_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450097.1"
                     /translation="MDILVRNINPKIITRIDKRCQELTTKTGKKWSRNQYLKILIEND
                     FDHELMNYKKDQFDLLFEKFIAIQAENTNILNDYVHTNNQLIETLIGGI"
BASE COUNT          738 a          334 c          394 g          846 t
ORIGIN      
        1 acaaattaga ttcattcatt cgtaatcaat tgcattattt tgtgaatcaa atagaaattt
       61 tttggaaaaa atctctttca gataatatgt gcgtttctta tgaagaaact agcatatttc
      121 cgaagaatca gtgttatttg gataaaaata tttattcaga tttgaaatgg gctgaagata
      181 taattggtca ttttaatagt tttttttatt caaatcaaag tcccactttt aaacatcatc
      241 atataaaaaa aaatcattgt ttaccaatat gggctttatt tgaagaaata acatttggta
      301 gtttaacaac atttattaat caacttaata cagagtatta taataattgg gtcatgagct
      361 gttatgataa tcctaaatac aaaaaagcta tacgaagttg ggcaaacgta attagagctt
      421 atagaaataa gatagctcat cattcaagaa tatatgcatt taaagttact gacgctccaa
      481 caatcataaa aaatgattcc aaaagttatt ttcctgaaaa taacttaaaa gaaacccaaa
      541 agttatattt gtatggagga ttatacgtta taaaacatct gttaatatat gaagatagca
      601 tgacacaaac tttatggaat aaatttctaa tagatttaga aaaaaagatc gataaaatcc
      661 cttccttaga aaaatccaat tatggttttc cggaaaattg gagaaacaag ttaaaaataa
      721 tgattgttta attgttattt aaattgttag tagacataat gtacatacta ccaagtagcc
      781 cctggatcaa ccgatccagg ggaagacttt gtgattttca attggtctat ctaaaacatc
      841 tttttaaaag cttgattctt cgctgttggc ttttttcgat tctttgtgaa tattcagtga
      901 ttattttttt actacttgtt attttccgag ggatttgtta aaagtttaat agcgtttctc
      961 agtaagggac gtcgtttttt cattttccta tgtatggact gctcgaacga gcagcctttt
     1021 tttattccag ggaacgtcct attctttgag tttccatgct attgaataac cgggacttag
     1081 ggattagggc agcgccccaa aatgaaaaaa gaaaaatccg cttctgcgaa ttcttctttt
     1141 ttttcgcaag ttggtaccaa cttgcaaatc ttgctggaag accgatccct aaaaagaaat
     1201 cgaggaattt ttttgttttt cggtttcttt ttttatcttt ttagaaagtt tgttgggtca
     1261 aaatttccag aagtaaaggt ttgattggtt tctttttgac gatttttggg ttgatttcgt
     1321 cgggaaggat tgagttgatt ttcaattttt tctttcactt cttgatatac tttagaattt
     1381 gtaccgataa gaacaccagt atcttttaga tataaatcag caaattctgc catgatttct
     1441 gtcatgatag aaatttcttt tcccatggca ttgagttttg cttggttact ggttgtggtt
     1501 gtattggtat caggttcata actcatacat aaaaagcgaa tggcttctga ataattgtta
     1561 acgtctggat ttttttcgat gatggaatct aaaacgtcaa cgtgactggg ataaagggtt
     1621 acgtgttttt gaacagaagt ttttctcatg ttatattcct ccgataagtg tttcaatgag
     1681 ttggttgttt gtgtgaacat agtcatttag tatgttcgta ttttctgctt gaatggcaat
     1741 aaatttttcg aataataaat cgaattgatc ttttttgtaa ttcataagtt cgtggtcaaa
     1801 atcgttttcg attaaaattt ttaggtattg atttcgactc cattttttgc ccgttttggt
     1861 tgttagttcc tgacaacgtt tatctattct tgtaataatt ttgggattga tatttcgaac
     1921 taaaatgtcc atggaaattt tcctttcgta tcagtgtata atttatgtat atcatacaaa
     1981 tatagtattt gtatagctat ttttcgccaa aacactatac atagcctagc cacaatggca
     2041 aaaaagtgat agcaaatttt tttctgagaa acgtgatagg cacagcttat ctagcacctt
     2101 tcgtaagaaa gtgataccac gtttccttat gctctttcaa aattcagaaa aatcagctgt
     2161 aaaacgagtg cagtccgagt aagattcaac gaaaaaacgg ggattggggc gccaccaaaa
     2221 tatcgcaaca tgggcccatg ttgctctgct cgcaaaagaa aaaagaagaa taaaaccagc
     2281 aatttttatt aatttaaatt gctggtttta tt
//
LOCUS       DARPZF010000136         2236 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.145, whole genome shotgun sequence.
ACCESSION   DARPZF010000136 DARPZF010000000
VERSION     DARPZF010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.145"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            301..1671
                     /locus_tag="SLE65_002877"
     CDS             301..1671
                     /locus_tag="SLE65_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4357 domain-containing protein"
                     /protein_id="HEI8450098.1"
                     /translation="MMDKSNEEQTTLYTKYWRRLEEVFDNSKGMEDFFRYYLAAITGE
                     YSAKHILYQAFKDYWHKERDVSSDAELLQKLVRYAGYFARLYYNKPEGKYSEVLSDFQ
                     SMESMMPAPFVLGLSEWYYHDQFITEDQYIDAIKVVNDYQLRRYFNGDDTSRVSKAFP
                     SYLKSVRKYAKANGYENIVDIVIYVLVTRNQSNNMALPSDKALKSNLLNANAYAMRLA
                     RWLLEKIENRENSATLDMSNLSIEHIMPQTSTSYWEEKAGTSGEEYTGLVNTIGNLTL
                     VTNPDNSAAGNKDFETKKKIFEDTLHIRMNKDLYELTEWTSSDISARSEALINELITM
                     YPYLRSSGDYEHDGNREIFLEAQGIKATGYLNEDETVIIHSGSEIYSKIKDIASDSLD
                     ETRQELLDNGIIEETIGGLQFVQDYTASSVSNAAALLLGGSRNGWDYWKYDNGISIND
                     SLRNKK"
     gene            1692..1976
                     /locus_tag="SLE65_002878"
     CDS             1692..1976
                     /locus_tag="SLE65_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450099.1"
                     /translation="MDKNKLRYAILKLRDEKKNPFIELKGQVPEEDILEQTKFLSRNG
                     LLESMVWADNTVHIWGSVSLEGEKYLVENSGLAKAYALAKEVKNWIPFWG"
BASE COUNT          768 a          324 c          467 g          677 t
ORIGIN      
        1 atatgttaga aacagttctc ataatttcct tgaatgttat aaaagtatct gtataatgtt
       61 cagtatattt tgatgaacgc atatgtagtc ctcatttctt gggagttttg agactactat
      121 atgcgttttt tgttgattta ccaacatgtt tagacatttt cctctaggaa aaaattaact
      181 agcaccacgc gtattgttta tattaaatta gatgaccgtg ataatgcaca gcaaattttt
      241 gaaagtatca attctaccgg tgaaagattg actgcctcgg atttgattcg aaacttcatc
      301 atgatggata aatctaatga agagcagact acgctttata ctaaatattg gcgtaggttg
      361 gaagaagtct ttgataattc taaaggaatg gaagactttt tcagatacta ccttgctgca
      421 ataactgggg agtattcagc aaagcatatt ctttatcaag cattcaaaga ctattggcat
      481 aaagagcgcg atgtatcaag tgatgccgaa ttgctccaaa aattagtgcg atatgctggt
      541 tattttgcga gactttacta taacaaacct gaaggaaaat actcagaagt attgagcgat
      601 ttccaaagta tggaaagtat gatgcctgca ccttttgttt tgggattatc tgaatggtac
      661 tatcatgacc aatttatcac tgaagaccaa tatattgatg cgattaaggt agtgaatgat
      721 tatcagctta ggagatattt taatggggat gatacaagca gagtgtcaaa agcatttcct
      781 tcatatttga aaagtgttag gaagtacgct aaagctaatg gatatgaaaa tatcgttgat
      841 attgtaattt atgttcttgt tactagaaat caatcaaata atatggcact tccatctgac
      901 aaggcattga aatctaatct attgaatgcc aatgcttatg cgatgagatt ggcccgttgg
      961 ttacttgaaa aaatagagaa tcgagaaaat tcagcaacac ttgatatgag taacttgtcc
     1021 attgaacaca tcatgccaca gactagtact tcatattggg aagagaaggc tggtacatcg
     1081 ggggaagaat acacaggatt agtaaatacc attggtaatt taacactcgt tacaaatcct
     1141 gataattcgg ccgcgggaaa taaagacttt gagaccaaaa agaaaatctt tgaagatacc
     1201 cttcatattc gtatgaataa agatttgtac gaattgactg agtggacatc atcggatatt
     1261 tctgccagaa gtgaagctct aatcaatgaa ctgattacta tgtatcccta tttgagatcg
     1321 tcgggcgact atgaacacga tgggaatagg gaaattttct tagaggcgca aggaataaaa
     1381 gcaactgggt atttgaacga agacgagacc gtgattatac attcaggttc agaaatttat
     1441 tctaagatta aagatattgc atctgattcg ctagatgaaa ctcgccaaga gctgttggat
     1501 aatggaatca ttgaagaaac aattggggga ctacaatttg ttcaagatta cactgcctca
     1561 tctgtttcga atgcagcagc tctgctatta gggggtagcc ggaatggttg ggactactgg
     1621 aaatatgata acggaataag tattaatgat tcgctaagaa ataagaaata gagcatagag
     1681 gtggtgttag gttggataag aacaaactaa gatatgcaat tcttaaattg cgtgatgaaa
     1741 aaaagaatcc ttttattgag cttaaagggc aagttccaga agaagatatt ttagaacaaa
     1801 ctaaatttct ttcgcgcaat ggcttactag aatccatggt ttgggcggat aacactgttc
     1861 atatctgggg gagtgtttct ctggaagggg aaaaatattt agttgaaaac tcaggtcttg
     1921 ctaaggcgta tgcattggca aaagaagtta aaaattggat tccattttgg ggctaagata
     1981 agtttttaaa cggagaaggt agcaaatcat aattggtttg ttgccttttt tgattgccca
     2041 aaaagaaaaa tgacaaagta tagagataaa tgacatagta cacgggaaaa atgacattgt
     2101 atcaccgaca acgtctaaat agatgttgat atatatacgt tccgtacaaa taattataaa
     2161 aatttaaatg atttgagtag aagtatcagt gaatatctca aggggaatag ctatctcaag
     2221 attcgatttt cacata
//
LOCUS       DARPZF010000137         2164 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.146, whole genome shotgun sequence.
ACCESSION   DARPZF010000137 DARPZF010000000
VERSION     DARPZF010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2164
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.146"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..111
                     /locus_tag="SLE65_002879"
     CDS             <1..111
                     /locus_tag="SLE65_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8450100.1"
                     /translation="YAVKLYKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            325..1020
                     /gene="vanR"
                     /locus_tag="SLE65_002880"
     CDS             325..1020
                     /gene="vanR"
                     /locus_tag="SLE65_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HEI8450101.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            998..2152
                     /locus_tag="SLE65_002881"
     CDS             998..2152
                     /locus_tag="SLE65_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HEI8450102.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          730 a          400 c          461 g          573 t
ORIGIN      
        1 tatgcggtaa agctatataa agaaggaaat atgactgtaa atcaaatttg tgaaattact
       61 aatgtatcta gggcttcatt atacaggaaa ttatcagaag tgaataatta gccattctgt
      121 attccgctaa tgggcaatat ttttaaagaa gaaaaggaaa ctataaaata ttaacagcct
      181 cctagcgatg ccgaaaagcc ctttgataaa aaaagaatca tcatcttaag aaattcttag
      241 tcatttatta tgtaaatgct tataaattcg gccctataat ctgataaatt attaagggca
      301 aacttatgtg aaagggtgat aactatgagc gataaaatac ttattgtgga tgatgaacat
      361 gaaattgccg atttggttga attatactta aaaaacgaga attatacggt tttcaaatac
      421 tataccgcca aagaagcatt ggaatgtata gacaagtctg agattgacct tgccatattg
      481 gacatcatgc ttcccggcac aagcggcctt actatctgtc aaaaaataag ggacaagcac
      541 acctatccga ttatcatgct gaccgggaaa gatacagagg tagataaaat tacagggtta
      601 acaatcggcg cggatgatta tataacgaag ccctttcgcc cactggagtt aattgctcgg
      661 gtaaaggccc agttgcgccg atacaaaaaa ttcagtggag taaaggagca gaacgaaaat
      721 gttatcgtcc actccggcct tgtcattaat gttaacaccc atgagtgtta tctgaacgag
      781 aagcagttat cccttactcc caccgagttt tcaatactgc gaatcctctg tgaaaacaag
      841 gggaatgtgg ttagctccga gctgctattt catgagatat ggggcgacga atatttcagc
      901 aagagcaaca acaccatcac cgtgcatatc cggcatttgc gcgaaaaaat gaacgacacc
      961 attgataatc cgaaatatat aaaaacggta tggggggttg gttataaaat tgaaaaataa
     1021 aaaaaacgac tattccaaac tagaacgaaa actttacatg tatatcgttg caattgttgt
     1081 ggtagcaatt gtattcgtgt tgtatattcg ttcaatgatc cgagggaaac ttggggattg
     1141 gatcttaagt attttggaaa acaaatatga cttaaatcac ctggacgcga tgaaattata
     1201 tcaatattcc atacggaaca atatagatat ctttatttat gtggcgattg tcattagtat
     1261 tcttattcta tgtcgcgtca tgctttcaaa attcgcaaaa tactttgacg agataaatac
     1321 cggcattgat gtacttattc agaacgaaga taaacaaatt gagctttctg cggaaatgga
     1381 tgttatggaa caaaagctca acacattaaa acggactctg gaaaagcgag agcaggatgc
     1441 aaagctggcc gaacaaagaa aaaatgacgt tgttatgtac ttggcgcacg atattaaaac
     1501 gccccttaca tccattatcg gttatttgag cctgcttgac gaggctccag acatgccggt
     1561 agatcaaaag gcaaagtatg tgcatatcac gttggacaaa gcgtatcgac tcgaacagct
     1621 aatcgacgag ttttttgaga ttacacggta taacctacaa acgataacgc taacaaaaac
     1681 gcacatagac ctatactata tgctggtgca gatgaccgat gaattttatc ctcagctttc
     1741 cgcacatgga aaacaggcgg ttattcacgc ccccgaggat ctgaccgtgt ccggcgaccc
     1801 tgataaactc gcgagagtct ttaacaacat tttgaaaaac gccgctgcat acagtgagga
     1861 taacagcatc attgacatta ccgcgggcct ctccggggat gtggtgtcaa tcgaattcaa
     1921 gaacactgga agcatcccaa aagataagct agctgccata tttgaaaagt tctataggct
     1981 ggacaatgct cgttcttccg atacgggtgg cgcgggactt ggattggcga ttgcaaaaga
     2041 aattattgtt cagcatggag ggcagattta cgcggaaagc aatgataact atacgacgtt
     2101 tagggtagag cttccagcga tgccagactt ggttgataaa aggaggtcct aagagatgta
     2161 tata
//
LOCUS       DARPZF010000138         2005 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.147, whole genome shotgun sequence.
ACCESSION   DARPZF010000138 DARPZF010000000
VERSION     DARPZF010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.147"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            129..1298
                     /locus_tag="SLE65_002882"
     CDS             129..1298
                     /locus_tag="SLE65_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEI8450103.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
     gene            complement(1638..>2005)
                     /locus_tag="SLE65_002883"
     CDS             complement(1638..>2005)
                     /locus_tag="SLE65_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HEI8450104.1"
                     /translation="KKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYG
                     FYQGTEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEG
                     TLFGFSVCTEIKVLLGIPA"
BASE COUNT          679 a          335 c          342 g          649 t
ORIGIN      
        1 aatatcccat attttaaaat aaaagatagc gtaaaatatt ttgtgtaaat agaaatttag
       61 ggtagaaaaa aaagtccatt ctgtaaaatt aaagttacca cacagaaatt ttataggagg
      121 actttctcat gactaaattt actatagaaa ttatgcaaac actactcaat aaaggggatt
      181 tagatgaatt atttcaggat catttagagc gagcgattaa ttcacttcta caagcagagc
      241 taactgcttt tttagattac gaaaaatatg atcgaaatgg attcaattca ggaaattccc
      301 gtaacgggaa ttattcacgt acatttaaaa cagaatatgg cgagttgaat ttaactattc
      361 ctagagatcg gaatggcgaa ttttctcaac aaacactacc agcatataag cgaaccaatg
      421 attcattaga aacgaccatt atccaattat ttcaaaaagg cattactatg gctgaaatct
      481 ccaaattaat tgaaaaaatg tatggtcacc actatacgcc acaaacaatc tccaacatga
      541 gtaaattggt ggctgaagat gttttagctt ttaaagaaag aacgttagaa gccaattatt
      601 ccgttatatt tatggatgcg acgcatatcc ctgtgaagcg acagactgtt tcgaaggaag
      661 cagtgtatat tacgattggt attcgtttgg atggaaccaa agaagttctt gggtttacta
      721 ttgccccaac tgagtctgct tatatttgga aagaagttct tcaagatctt agaaaacgtg
      781 ggttagaaga agttttatta gtagtgacag acggattaag ctgtattgaa gaaagtatcc
      841 atagtgtgta tccgaatgcc caatttcaac aatgttgtgt gcatgtatct agaaatatcg
      901 ctcataaagt tcgtgttcga ggtcgaaaag aaatttgtga ggatttcaaa ttggtttacc
      961 aagcgaattc aaaagaagag gcattggatc acatcgactt tatgactagg aaatggaaaa
     1021 agcagtatcc aagagtcgtc aatttactct tgaatcctgc cctattaacc ttttataatt
     1081 tccctcacgc catcagacga acaatttatt cgacgaacct gattgaaggc tttaataagc
     1141 agctaaaacg atatactcga agaaaagaac aattccctaa tgaagaatct ctagagagat
     1201 tcttcatttc tcaatttaat caatataacc aaaaattttt aggtagaatt cacaagggat
     1261 ttaaagaaat tcaggataca ttagagtcga tgatttaact gtaattaaca gaatggattt
     1321 tccatttaca tataattctt gacgctacca taatctaaat aaccatcata ttcatctact
     1381 acttatataa ttgagtttta ttaaactttt taagtttcta ttctatcaaa tatttaaaca
     1441 atctctgcat ccgaaaagac tacctcgtat agttttacta acaatatttt tattagcgtg
     1501 ttcaaatcct gatttcttgt atcaattatt ttctgttcac tttcaataag aaaaaagtct
     1561 ttacttccat ggataataat aagggttctg ttgcaaagtt ttaaataaag aataaaatcc
     1621 cttacggtat ctatgattta agctgggatt cccaataata ccttgatttc agtacagacc
     1681 gaaaacccga agagagtgcc ttcttttcgg gttttcttat ataatcctcg gatggcttcc
     1741 atgcctttaa tcgttgtaga ggcagtgcgt aaacttcgat agaatttatt gcgtctcttt
     1801 actggacgat ggtcttgttc aatcaaatta ttcaggtatt taatggtacg atgttctgtc
     1861 ccttgataaa agccgtattc ttttagtttc ttaaaggcac ttgtaataga gggggcttta
     1921 tctgtgacta caaccttcgg ttcatcaaac tgcttcacta accgcttaag aaaagcatag
     1981 gctgcttgtg tgtcccgttt tttac
//
LOCUS       DARPZF010000139         1980 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.148, whole genome shotgun sequence.
ACCESSION   DARPZF010000139 DARPZF010000000
VERSION     DARPZF010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.148"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(325..529)
                     /locus_tag="SLE65_002884"
                     /pseudo
     CDS             complement(325..529)
                     /locus_tag="SLE65_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(729..1745)
                     /locus_tag="SLE65_002885"
     CDS             complement(729..1745)
                     /locus_tag="SLE65_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEI8450105.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPISFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERK
                     KVIVPKEIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDKIVIDGL
                     IAEPSNWSIIARHTKYKYRNLLKQESQNDELTNHLRETFKESADELKKELDTWLLGLD
                     VTEK"
BASE COUNT          558 a          459 c          309 g          654 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggttttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cacgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaaaa attttcctaa ttgtgacatg gctgtcacaa
      541 ttccaaatgc tctccgaggg tattcgctgt cacaagtgac aacgaaaaaa ggagccgaaa
      601 gcgtgtcacg ctctcaactc cttttacgct ttattttgct tcatgcaaaa tattcgctta
      661 tcgtgaattt acgtcactaa acattgacgc aaatccactc tcactcatct gacttttctt
      721 attcggtatc acttctctgt cacatccaac cccaaaagcc acgtatccaa ttcttttttt
      781 aattcgtctg cagattcctt aaacgtctct cgtaaatgat tcgttaactc atcattttga
      841 ctttcttgct tcagcaaatt ccgatattta tattttgtat gtctagcaat tatcgaccaa
      901 ttagaaggct cagctatcaa accatcaata actattttat caataggttt tatatcaatc
      961 ggcaaaaaat gcgggcttgc aaaactatct aagctttcct gaaccatcgc atgccaatcc
     1021 gttgctttgc cacgtcttag ctgcatttct aaccgccacc acgtatcgat ttcttttggc
     1081 acgattactt tttttcgttc ctgctctagc tttttgttgt acagtcgcac ttggcgctca
     1141 ctggcacgac tgccccagta cgctgtttct agcttgccag aacggccgta gattggctta
     1201 aaagaaatcg ggtctacaat acgatactga gtaataaagt catccggcac atctacaata
     1261 tcgcaggcaa tatccgcccg ggaaaaatgc ggatctaaaa ataggtcatg aatgaatcct
     1321 ttcatggaac tagctaaaaa ctggcctatc ttattcggat taaaatcaat acgacctttt
     1381 ccttcatgaa atttaagtat ttcgatatac gcaatatctt ctccatattg atcgaataat
     1441 tgccagccgt ttatcccaac tgatttcaaa tatccctgat tttcgttcaa acgcattaat
     1501 tgctcgaaat cgacaaaaac aactccattt ttcgtccaat aagctatggt atcattcagt
     1561 tttccgacaa ttgtaattcg atcaatcgac caatttaatt ttaggggggt ggtcgtacct
     1621 tgcacactta accgcctgtt agaaatacgg ttaagttttt cgagctgatt tatcgttgtt
     1681 cttttttctg cccctcgacc ttcaattttt gattgaattt cactcaactg attttcattt
     1741 gccattttcg tcctccaaac gaaaaaagag acttttggaa agaatttcca gagttcacgt
     1801 aaccctaaaa attcatatcc aaaaatctct agcttgaaga aacctaaaaa tattcgtata
     1861 atgaacctga gttacggagc taggtgaagt agtttccgta aatagtcgag agtgttagcg
     1921 cactgctcgg cttttatttt gctctttttt ctcgttttct ttgattatag cactcctcct
//
LOCUS       DARPZF010000140         1863 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.149, whole genome shotgun sequence.
ACCESSION   DARPZF010000140 DARPZF010000000
VERSION     DARPZF010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.149"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..830)
                     /locus_tag="SLE65_002886"
     CDS             complement(<1..830)
                     /locus_tag="SLE65_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEI8450106.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELDSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     T"
     gene            complement(841..>1863)
                     /locus_tag="SLE65_002887"
     CDS             complement(841..>1863)
                     /locus_tag="SLE65_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HEI8450107.1"
                     /translation="ELKPKHERQNFLVGDDRLDHAVAFLWKDPQTGETVGASYQGTIV
                     DFNRFGKRGTYKHIDKNPTPNHGFNLKIGDPKHLKFFESSIDLLSYAALNREKLQDAW
                     LVSMDGLKHHVISHYVEESISELRRKQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDP
                     FTNKKIRCERGIPNDWQVPKEYKATYEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVS
                     AHDVQSTFGKMLAKGEPVETIDLKEACTTVAKELKVCERADGTYNFDRFYSRKANIKD
                     VNAGILLSYKAEQYYKGYKKHEHEFVPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQG
                     RQQERE"
BASE COUNT          459 a          402 c          327 g          675 t
ORIGIN      
        1 gtttcgactt gaaggatcgt acctggctgt tttcctaatt gaacaccttt ttcttttaaa
       61 taggcttcaa atgcttcttg tgtcgcttgg gtttcatttg gatcaagctt cgcatcaaat
      121 gcgccatttt gagcgattac ttgggctttt ccttcaaaat atggttcttt ttggaagttt
      181 ctaatctttt cctgcaattg ataaatcata tagagtgttg gggtttggac tctacctaaa
      241 gaaaaacttc ctggtatgcc tttttgctgc aagagtaaac tatacagtgg gctaccgttc
      301 atcccaatta accaatcggc gatctgacgt gcttgtactt cttcaaattt tggataggtc
      361 tcttctgcgt ctcgtaactg ttggaatccc tgataaatgg cttctttttc taaggagttg
      421 atccaaagtc ttttaaaggt ttttccttga ttggcgcctg cttgttgaat gattgaccag
      481 gcaatcagct ccccttcacg atcgctatca gtcgcgatca caatcgtatc agctgactgc
      541 agctgtcgtt tgacgacact aaactgcttt ttcttatctt taggaacatg atagtggtat
      601 tgattgggga aaataggcaa atgttctaat gcccattgtt tccatttttc atcgtacata
      661 tcgggcgaat ctaactcgac taaatgacca aaaccatacg tgatcacagt ttctcctgta
      721 aacaatcgat cttggatctc aaaataccca tcttttcggg tagctttaga aaagctatcg
      781 gcataagcct tcgcttgtga cggtttttct gctaaaatga cggttttcat agtgacgact
      841 tcactccctt tcttgttgtc tgccttgttg aaacaacatc gcacgttttt gctttctgat
      901 ttcttgttgc tggatctcat gcttcaattg atcattccaa tcctttttca cttcaggtac
      961 aaattcatgt tcatgctttt tatagccttt gtagtattgt tctgctttat aggaaagaag
     1021 gattcctgca ttaacgtctt ttatgttggc ttttctacta taaaaacgat caaagttgta
     1081 tgttccatct gcgcgttcac atactttcag ttccttcgcg accgtggtac atgcttcttt
     1141 caaatcaatt gtttctactg gttcgccctt cgccaacatc tttccaaacg tagattgaac
     1201 atcatgagca gacaccaatt gatttgtcag ctgtaaatta gtttcagttt tgtgtatggc
     1261 cataattgct tcaggttcaa cactcatttc ttttgcgact gcttcataag tagctttgta
     1321 ttctttaggt acttgccaat catttggaat tcctcgctca caacggattt tcttattggt
     1381 aaaaggatca acgattccct tcatctgttc tttttcataa aaaatatgtc ctgcacgatc
     1441 attgtccaca catatttcaa tcgattgagg aaatgtttgt tttcgtctta attcagaaat
     1501 cgactcttca acgtaatgac tgattacatg atgttttaac ccgtccatcg aaactaacca
     1561 ggcatcttgt agtttctccc gattcaatgc agcgtaactt aacagatcaa tactactttc
     1621 aaagaatttt aaatgcttcg gatcgcctat ttttaaatta aatccgtgat ttggcgtagg
     1681 attcttgtca atgtgtttat acgttccccg tttaccgaaa cgattaaaat cgacgatcgt
     1741 tccttgataa cttgccccta ctgtctctcc tgtctgtgga tctttccata aaaaagcaac
     1801 cgcatgatct aaacggtcgt ctccaactaa aaaattttgc cgttcatgtt tcggctttag
     1861 ttc
//
LOCUS       DARPZF010000141         1854 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.150, whole genome shotgun sequence.
ACCESSION   DARPZF010000141 DARPZF010000000
VERSION     DARPZF010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.150"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..830)
                     /locus_tag="SLE65_002888"
     CDS             complement(<1..830)
                     /locus_tag="SLE65_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEI8450108.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     T"
     gene            complement(841..>1854)
                     /locus_tag="SLE65_002889"
     CDS             complement(841..>1854)
                     /locus_tag="SLE65_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HEI8450109.1"
                     /translation="ELKPKHERQNFLVRDDRLDHAVAFLWKDPQTNETVGASYQGTFI
                     DYERFGERGTYKHIDKNSTANHGFNLKIGDPKQLKFFESSIDLLSYAALNRDQLNDTW
                     LVSMEGLKHHVISHYFGEAVSELRKKQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDP
                     FTNQKVRCERGIANDWQVPKEYKVIYEEVAKEEKITPEAIMAIHKTENNLQLTNQLVS
                     AHKVNASFGQQLSVNDSIEAINLKDICREVAKELKACERVDGTYDFDRFYQEKGDINA
                     QILFSYKAEQYYKGYKNHEHEFVPEVKKDWNDQLKHEIYQQEIRKQKRAMLFQQGRQQ
                     ERE"
BASE COUNT          471 a          399 c          322 g          662 t
ORIGIN      
        1 gtttcaactt ggtggatcgt acctggctgt tttcccaatt gaaccccctt ttcttttaaa
       61 taatcttcaa atgcttcttg cgtcgcttgg gtttcattcg gatcaagctt cgcatcaaat
      121 gcgccatttt gagcgattac ttgggctttt ccttcaaaat atggttcttt ttggaagttt
      181 ctaatctttt cctgtaattg ataaatcatg taaagcgttg gggtttggac tctgcctaag
      241 gaaaaacttc ctggtatgcc tttttgctgc aagagtaaac tatacagcgg gctaccgttc
      301 atgccgatca accaatcggc gatctggcgt gcttgtgctt cttcaaattt tgggtaggtc
      361 tcttctgcat ctcgtaactg ctggaatccc tgataaatgg cttctttttc taaggagttg
      421 atccaaagtc ttttaaatat ctttccatga tcggcgcctg cttgttgaat gatcgtccaa
      481 gctatcagtt ccccttcacg atcgctatct gtcgcaataa taatggtgtc ggccgattga
      541 agttgctgtt tcaccacctt gaattgcttt ttcttatctt taggaacatg atagtgataa
      601 tgtgtaggga aaataggcaa atgctctaat gaccattgtt tccaattttc atcgtacata
      661 tcgggcgaat ctaactcgac taaatgacca aaaccatacg tgatcacagt ttctcctgaa
      721 aacaatcgat cttggatctc aaaataccca tcttttcggg tagctttaga aaagctatcg
      781 gcataagcct tcgcttgtga cggtttttct gctaaaataa cggttttcat catgacgatt
      841 tcactccctt tcttgctgtc taccttgttg aaacaacatg gcacgttttt gctttctgat
      901 ctcttgttgg tagatttcat gcttcaattg atcattccaa tcctttttta cttcaggtac
      961 aaattcatgt tcatgatttt tatagccttt gtagtattgt tctgctttat aagagaaaag
     1021 aatctgagca ttaatatccc ctttttcttg ataaaaacga tcaaaatcgt acgtaccatc
     1081 cacgcgttca caagctttta attcttttgc gacttctcta caaatatctt tcaaattaat
     1141 agcttctatt gaatcgttaa cagaaagctg ctgaccaaaa gacgcattta ctttgtgagc
     1201 ggaaaccaat tggttcgtta attgcagatt gttttctgtc ttgtgtatgg ccataatagc
     1261 ttctggtgtg atcttttctt cttttgcgac ttcttcataa atgactttgt attcttttgg
     1321 cacttgccaa tcattagcga ttcctcgttc acaacgtact ttctgattcg taaatggatc
     1381 aactgcgccc attaattgtt ctttttcgta gaaaatatgt cctgcacggt cattatccac
     1441 acaaatctcg atggattgag gaaaggcttg tttctttctc aattcagata ctgcctcacc
     1501 aaaataatga ctgatcacat ggtgttttaa cccttccatc gaaactaacc acgtatcgtt
     1561 taactgatca cgatttagtg cagcatagct aagtaaatca atactactct caaaaaattt
     1621 taactgctta gggtcaccga tctttaggtt aaagccatga ttcgctgtcg aatttttatc
     1681 tatatgctta tatgtgcctc tctcaccaaa acgttcataa tcaatgaacg ttccttgata
     1741 actcgcccct actgtctcat ttgtctgtgg atctttccat aaaaaggcga ccgcatgatc
     1801 taaacgatcg tctcgaacta agaaattttg ccgttcatgt tttggcttta gttc
//
LOCUS       DARPZF010000142         1808 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.151, whole genome shotgun sequence.
ACCESSION   DARPZF010000142 DARPZF010000000
VERSION     DARPZF010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.151"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            24..>1808
                     /locus_tag="SLE65_002890"
     CDS             24..>1808
                     /locus_tag="SLE65_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450110.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEK"
BASE COUNT          594 a          327 c          303 g          584 t
ORIGIN      
        1 aagttttaga aaggaatacc tttatgtctt tttttaataa catatataat aaaaaagaat
       61 ctttttattt acgtataaag tggagcataa tcattatatt atcattgtta tttttaacag
      121 gaattgctta tttcttttat tttatttttt ctcctgcgga cagcaatcaa atgaaagaaa
      181 taaaagattc gtgggttttc tatacaaaag atgatcctga ttttaagttt gacagcaagt
      241 acactcgtac gattcctacc gtggataaag acgaaacatt cattatggaa acgacacttg
      301 aaaaaccgtt ggacgaagca aatttactaa tcaaaggaaa ccatcaatgg attactgtat
      361 atctaggcga aaagatttta taccaacgga aagattatca ggaagaaagc aatcccggac
      421 tctcattggc tgtgatagat ttaccagcaa attatatcgg aaaaaaattg acccttacag
      481 tctcatctcc ttatcagaac tatgctggac tgccaccgaa agtttatcta ggaacaactg
      541 gaccattgat tagttttatt tattcacaat cagtgccgca agtattgacg atgataatcg
      601 ctgtttttat cgctataggg acctttttct atacgatcta cttgatgtat aaacaaaaac
      661 gtcttgaata ctcacttatt ctcttaagtt gctttgcttt ggcattagga tttgaagctg
      721 tatcagaaga tattttaagt ggtattcttt ttgaaccatt cgttcattct tttttatctc
      781 atttatttat tatcttaacg tcagctttca tcatctgcta ctattggagc cgaatgtttt
      841 actataaaaa atggtacgga attttttgta cgttccaact tttgattttt atcggcgttc
      901 tgctttatgc aacttttact cctgcagaac ttcctgaatt aatgccgatt gctaatattg
      961 ctagtgttat aagcacttta gtcacttcac ttgcatgcat tggcgaagca tataagaata
     1021 accgttttta tgtagcttgt acaccttgga tcgtcttggt agccattatc cattgcttga
     1081 tttacatcca aacggcatta ggtatctatc aaacaacgat caattggtct acgattttat
     1141 atattatcat tctaatcgtt attatcagct acaatctaat cgatcacatc ttaaataccg
     1201 acaaagatcg gagacaagta gatttcttaa aaatcaaaaa tgatttgttg gagcaacatt
     1261 atgagcagct tcgacagcat atccaagaag taaatacact tcgcctggaa tttgtccaag
     1321 agatggagaa tctgcaagat ttaatgcata cggaccaaac aaaagctaaa aactatgtgg
     1381 aaaagatatt agaagaagca aaaaatttcg aaatgctgtg ttctttttgc aaccaccagg
     1441 tgacaaatct tatcttagcg cgttaccaga agttagctgc caaacggaat attcagataa
     1501 ccttccaagc agatcttccc gaagaacttc ctatcaacga tgacgatctg gctcaacttt
     1561 tgatccacgc tttagagcat tcctttagag aaactcatgc catcgaaaat ccactgtatc
     1621 gaaaaattta tttgtcgata cacgaacaag aggaacattt cgtcatttgt tgcgaacata
     1681 gtgcacatta cgatacaaac ctatttagtc gaggcatcac agaagaatta gatgatcagg
     1741 aacgttttga cttaatgatg atgaaagacg tagcggatcg ttacacagga acactaacgc
     1801 aggaaaaa
//
LOCUS       DARPZF010000143         1748 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.152, whole genome shotgun sequence.
ACCESSION   DARPZF010000143 DARPZF010000000
VERSION     DARPZF010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1748
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.152"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(150..557)
                     /locus_tag="SLE65_002891"
     CDS             complement(150..557)
                     /locus_tag="SLE65_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450111.1"
                     /translation="MPKDFDIPKMMENGEFEPLLPNNKRQDVKISGEYNFSNSALSNT
                     RNITLKKRGRPVSIPDKRNKVSVPKKISPALNSKLSILQDYMTELQSEKGRISFEKIV
                     NTLADSYIQHRLGVAKEEHIREEIQEEFEKLPK"
     gene            complement(576..1394)
                     /locus_tag="SLE65_002892"
     CDS             complement(576..1394)
                     /locus_tag="SLE65_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEI8450112.1"
                     /translation="MDTFQGTTFTVGNFKGGVGKTKIVSMLAYDNAMIRNRKTLIIDL
                     DPQANLTQVIARTFGITDIKTTITNGVANGELASSIIKVNENLDLLACDTSFRSFSAF
                     ANKHENELDQVTVLKKLLLPIKNNYQEIFIDVPPTISEFSDNAMAASDYSIISFQTAE
                     ESLEGVNKYVNYQKFMVDRYDLDLQIIDIVPCMVEPNDDFDEEILEEAIEKYGTVVSK
                     NLIHYQKRLRRYSKIGIHLRKYKNGNFDQWDYKAHQVFINILAELDARQEFLNK"
BASE COUNT          532 a          274 c          230 g          712 t
ORIGIN      
        1 ttaaataata attttataat gttgatttaa tcgcaaattt acacgttgtt tattaagtta
       61 taccttaaat atttaatgta taacttatac tttaatattc atttatctag tataacttat
      121 actttaattg aataccgcat gaaaaaaaat tattttggta atttttcaaa ctcttcttgt
      181 atttcttctc ttatgtgttc ttcttttgct actcctagtc tatgctggat atatgagtct
      241 gctaatgtat taacaatttt ttcgaaagaa attctccctt tttcactttg taactccgtc
      301 atatagtctt gtaaaattga gagtttgcta tttaatgccg gagagatctt tttaggaact
      361 gataccttgt ttcttttatc aggaattgaa actggtcggc ctcttttttt caatgtaata
      421 tttcttgtgt tactcaatgc actattgcta aagttatatt caccgcttat tttcacatct
      481 tggcgtttgt tattgggtaa taatggctca aattcaccat tctccatcat tttaggaata
      541 tcaaaatctt taggcattac ttatgcaact ccttattatt tatttaaaaa ctcttgtcta
      601 gcatctagtt ctgccaaaat atttataaat acttggtgtg ctttataatc ccattgatca
      661 aaatttccat ttttgtattt tcttaaatgt ataccaattt tagaatacct tctcaatctt
      721 ttttgataat gaatgagatt tttggatacc acggttccgt atttttcaat tgcttcttct
      781 aggatttctt catcaaaatc atcatttggt tctaccatac aaggtacaat atctataatt
      841 tgcaaatcaa gatcgtatct atcgaccatg aatttttgat aatttacata tttgttgact
      901 ccctctaagg attcttcagc tgtttgaaat gaaattatcg aatagtctga agctgccata
      961 gcattatcgg aaaattcgct aatggttggt ggtacatcaa taaatatttc ttgataattg
     1021 ttctttattg gaagaagtaa ttttttcaag acagtaactt ggtctaattc attttcatgt
     1081 ttattagcaa aagcggagaa tgatcgaaaa ctagtgtcac atgccagaag gtcaagattt
     1141 tcatttacct taataatact acttgctaat tctccatttg cgacaccatt tgttatagtg
     1201 gttttgatat cggttatacc gaaagttctt gctatgactt gtgttaagtt cgcttgaggg
     1261 tctaaatcaa taataagcgt ttttctattt cttatcattg cattgtcata agcaagcatg
     1321 ctgactatct tagttttacc tactcctcct ttaaaattgc caactgtaaa tgtagtccct
     1381 tgaaaagtat ccatgtaaat cctcccaatc tttaattgat aattaaagta taacttatat
     1441 atcggaaatg gtcaacatta aaagtataac ttaaataata atatctaaaa acgtttggat
     1501 atagcggttt ttaataataa aagtataagt tataccatat atatttatgg tataacttat
     1561 acttttatta ttaaaggtat aacttatacc ttaaatattg cttttcgaaa atagctattc
     1621 tagtctatct gtttctttac ttttcgctgc tgatttgaat tgaattgatc atattcattt
     1681 tctagtatta ataacttttc gtatacatcg gtcatattca tactagaagc aagacttaga
     1741 tcatatac
//
LOCUS       DARPZF010000144         1718 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.153, whole genome shotgun sequence.
ACCESSION   DARPZF010000144 DARPZF010000000
VERSION     DARPZF010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.153"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(606..962)
                     /locus_tag="SLE65_002893"
     CDS             complement(606..962)
                     /locus_tag="SLE65_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEI8450113.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWFEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(976..1386)
                     /gene="spx"
                     /locus_tag="SLE65_002894"
     CDS             complement(976..1386)
                     /gene="spx"
                     /locus_tag="SLE65_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEI8450114.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
BASE COUNT          530 a          315 c          241 g          632 t
ORIGIN      
        1 tgtttgttgt cttgaattga atcaagacgc cctacacatt tggtttgtct tactttgttc
       61 agttttcaaa ggtctacttc atcaggagtg ttccccgatt cgtttttggc tgccgtagca
      121 acttttatat catatcagag agacaagtaa ttgtcaactc ttttttaaaa gtttttttga
      181 tttcgttttt cgaaatctta cagcaactca tttatcataa cttatcattt gttatttgtc
      241 aaggactttt ttgaagtttt tttcgataga atcaagcttc acaagtggtt cttttttaac
      301 aactcagtta tcttatcatg tcatttctaa catgtcaaca actattttat atgtttttta
      361 aaatactatt ttattgcttt gctacttaaa acaacagaaa tgaatatatc atgtaaattt
      421 acacatgtca atatattttt aactctatat ccccacctag atttgaattt tgaccacata
      481 aattgagcat gtctctatag tagaaaaata aagtcaaaaa aagaacacat aacacgcttg
      541 atgctaagtg ttcgactgtt acaactgtat gaaatgctca gtgacttgat taaaacagtt
      601 aaagtctatt tatttaagat aagctgttcc atcaactgct cattgtatcc aataaataga
      661 acttcatcga taataatcaa aggacgtctg aggagattgg tatgttgtgt gcataaaaaa
      721 atcagttgtt tttttcctac acaggaaagg tcaatcgcaa tgttgtgaaa agcctcaaac
      781 caagtcgcaa atagctgttc tgcttgcact tcttcaaaac tgcataattc ttctgcttct
      841 tctgtactta gatcgcgttc ttctaagtca acaaattgat aaggcaattg atggtgttct
      901 aaccattgtt tcgccttcag acttgttaca cagtgcgctg atccatagac tttcacttcc
      961 acgaaggctc cctccctatg aatttaagat gttattgttt tgtaaataga tcagatttct
     1021 ggcaacacat cgaatttcac gagggacaaa tgaccggatc tcatcttcat taaatccgat
     1081 tagtattctt ttttcatcaa tcaaaatagg tcgtctcaat aatgaaggat attctttgaa
     1141 taagacgatc atttgcttta aagttaattc gttaaaatct atgcccagct tttcgtaaat
     1201 tttcgaccga gtggaaataa tatcttgaac tcctccttca gtcgctgcca agatcttttt
     1261 gatctcactt tctgttaacg gttcggcaaa aatattcttc tcttcaaatt caagttgatt
     1321 cgcttgcaac catgctcttg cttttctaca ggaagtacag ctaggcgaag tatatacttt
     1381 tatcattttc tcactccttt ttaattataa tccaattcta cagtaatttc ttttaaaata
     1441 ccaattatta gctaataaaa tataaaaaaa atcaaaataa ctgattattt acgtttgaat
     1501 aatgagaatt tttctatata ttctctattt tgataatagt attctcattt tcaaaataaa
     1561 taagggaggt gtgacaaaat tcttgtcaca cctccctttt ccgaataaac tgtgttccag
     1621 aaatagcttc ttcgaaaata agctgaaatt tcacaaaaat ttgagaagca attttcgtac
     1681 attccttctt ctttcttgaa actgaccact tctgtcac
//
LOCUS       DARPZF010000145         1717 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.154, whole genome shotgun sequence.
ACCESSION   DARPZF010000145 DARPZF010000000
VERSION     DARPZF010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1717
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.154"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..374
                     /locus_tag="SLE65_002895"
     CDS             <1..374
                     /locus_tag="SLE65_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8450115.1"
                     /translation="CDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSLIENQDL
                     LTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQKF
                     LNRSHKGFQQVTDTLVSMFTE"
     gene            711..950
                     /locus_tag="SLE65_002896"
     CDS             711..950
                     /locus_tag="SLE65_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450116.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(1312..1572)
                     /locus_tag="SLE65_002897"
     CDS             complement(1312..1572)
                     /locus_tag="SLE65_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450117.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
BASE COUNT          586 a          315 c          240 g          576 t
ORIGIN      
        1 tctgtgatga ctttaaggct gtttatcaag ctaactcaaa agaagaagcg aataccttct
       61 tatccggcat gattgagaaa tggaagaaaa actatcctaa agtgacgcag tcactcatag
      121 aaaaccaaga cttattaact ttttatgatt ttccacctag cattcgtaga accatttact
      181 caaccaatct aatcgagtct ttcaataagc aaattaaaag atacagccgt agaaaagagc
      241 agtttcaaaa tgaagaatca ctagaacgct ttctagtcag catttttgat acatacaatc
      301 aaaaatttct aaacagaagc cataaaggtt ttcaacaggt aaccgataca ttagtttcaa
      361 tgtttactga gtaactaatt attttgcagg aggacaattt atttacacaa aattattgac
      421 gctcccagct atcctcctag caactattta aatacccaaa aaaattacct ctagataata
      481 tcatacctac gttttcactt ataaattttt tcataaaaaa agcgtttaga ggcataatcg
      541 ttaatacaga tggtaaccaa tgtatctggt ttgaactggg atatcaccct ctccatatat
      601 gtattactaa gactaataga tactataaaa gacttgatag ttttgcattg attttgccta
      661 atactgagca taggtgtatg ctaaacgata ctataaggag tgtgtacata atgaaaagaa
      721 ttctgtttat cagtttatca aatttattgt tacttactgc ttgtgggact tctgcatcaa
      781 agaacatacc ttcagatacg caaatttcga atagtatcga ttcaacaatt tctacaaatg
      841 agaaaaattc tccggtagaa acttccgata taaaagtttc tacctctgca aaaaacaggg
      901 taaagaaact gtcagcacgt ctcctttatt tcaaacaaac tctgaattag cttcttcatc
      961 ttcttcagca aataatgatg atagtttcgc gtttactcct aactaaatgc aacctttaca
     1021 aatgctttac gataacaagc ctgagctaaa tgatcctgat atcagttttg cattttttga
     1081 aatgattgga tcggatgatc tttttaaaac tactagtttg tctatccgaa aataggacag
     1141 ttctggcagt ataggttttt atcgagtttc tccaccaggc ctcgttacag agacagattc
     1201 tctaggcgaa ccttttgaat aaatcaaaaa tcatgaacaa tcactgccaa ctaaataaag
     1261 tgccttcaaa agcttggtct tctcgctttt gaaggcactt tatttaaatc tttatgaaac
     1321 taaagtatgt tcatatttgt tgctatagtt atatagatat tctgttgttt ccaactcata
     1381 aacgtgagta tattttgcca ctacttttcc gcatttttct aatatttcat tgcgatcgac
     1441 gtcatgatat tcgtctacgc agatcacaac acaattttct aatttactga ttacttctcc
     1501 aaccactttt tgtttcaagc caataggttg gcaaatatat ttttttccta aaatgatagt
     1561 ttcgttattc atatttcatc catccttaat gtttttccat tatttaaaat gataatacca
     1621 ttaaaatatg attatgaaaa tcaataacac ttgtgatttt ataaaaaaat aaaaaaaccg
     1681 aaaaacagaa atgcccactg tctttccggc tcttttt
//
LOCUS       DARPZF010000146         1693 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.155, whole genome shotgun sequence.
ACCESSION   DARPZF010000146 DARPZF010000000
VERSION     DARPZF010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1693
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.155"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(53..787)
                     /locus_tag="SLE65_002898"
     CDS             complement(53..787)
                     /locus_tag="SLE65_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEI8450118.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="SLE65_002899"
     CDS             1114..1524
                     /locus_tag="SLE65_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HEI8450119.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..>1693
                     /locus_tag="SLE65_002900"
     CDS             1517..>1693
                     /locus_tag="SLE65_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HEI8450120.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYN"
BASE COUNT          543 a          295 c          325 g          530 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aat
//
LOCUS       DARPZF010000147         1655 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.156, whole genome shotgun sequence.
ACCESSION   DARPZF010000147 DARPZF010000000
VERSION     DARPZF010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1655
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.156"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            200..742
                     /locus_tag="SLE65_002901"
     CDS             200..742
                     /locus_tag="SLE65_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450121.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..1347
                     /locus_tag="SLE65_002902"
     CDS             898..1347
                     /locus_tag="SLE65_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEI8450122.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPDGMATLFLTKIIRCCECCGVMAPIALDNEHPRI"
     gene            complement(1377..>1655)
                     /locus_tag="SLE65_002903"
     CDS             complement(1377..>1655)
                     /locus_tag="SLE65_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8450123.1"
                     /translation="GITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQFETLAQLRLE
                     LFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          624 a          236 c          319 g          476 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tcttgatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccagatgg aatggcaaca
     1261 ctttttttga caaaaattat aaggtgttgt gaatgctgcg gtgttatggc tccgattgcc
     1321 cttgacaatg agcatcctcg gatctgattt tctccggcag aagcacaatc attcaattac
     1381 gctgcctctc cagaggtatc agatccgcgc tcattatcaa ggattcgctt cgccaatctc
     1441 tgttgtcgaa tttggatcgg tgtttcatac gccaacgtgc catgtaagcg tagatagttc
     1501 caccaatgca cataatcaaa caattctaga cgtagctgtg ccagtgtctc aaattggtat
     1561 tgatgcacga attctacttt gacagattta taggttgatt ccacaacggc attatcatac
     1621 ggacaaccct tcctactcaa tgaacgagta attcc
//
LOCUS       DARPZF010000148         1648 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.158, whole genome shotgun sequence.
ACCESSION   DARPZF010000148 DARPZF010000000
VERSION     DARPZF010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1648
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.158"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            97..390
                     /locus_tag="SLE65_002904"
     CDS             97..390
                     /locus_tag="SLE65_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450124.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            387..611
                     /locus_tag="SLE65_002905"
     CDS             387..611
                     /locus_tag="SLE65_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEI8450125.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            608..1633
                     /locus_tag="SLE65_002906"
     CDS             608..1633
                     /locus_tag="SLE65_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEI8450126.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPQR"
BASE COUNT          575 a          264 c          339 g          470 t
ORIGIN      
        1 tatgcattac agacgaagaa gcagataaaa tcattagcaa agaagagagc gcatcttaat
       61 tgatgtgctt tttattttga ttcaaggagt tgtcacatga ttaatttagg ggaatgggga
      121 gcgatagcag gatcaataac cgctatcgtt tctttgattt tattagtaat aaaaccaatt
      181 actgcatctt tctcgaagat tactgagact ctttcaaaag taagtcacaa tttagatttg
      241 ctgactaaag atttagaatc gagcaaatca gatcgattga tgattcatga agaactaaag
      301 aaacacgatg aaagattaga tacacatgca gaaaaattgg tagaacacac gcaacaaatt
      361 aaaactttat ttagggagag aagaaaatga ataataaaac gttcgaagta ctaaaatggt
      421 tcgcactggt aattattccc gcactagcta ctttcgtggg gttagttggt aaagcgctca
      481 attggcagta cacagatatc tgtgttgtca tcattactgg ttttggcgcg tttttaggga
      541 gtgtgttggg tgtatcaaat cgaacctaca aaatgttctc ggctgaaagc gaagaaggag
      601 gaaacaaatg aaaaagaaaa ttactattac tgcgatgagc ctgttaacgg ctcttttttt
      661 attacccatt aatacgtttg cttatactat taatgacgag tataatttag cgccgaatca
      721 aggagactcc agattagcaa ttcctaacaa aattattttg cacgaaactg gaatagatgc
      781 accagcaaga aacgtagccg ccaacatgaa aaataattat aacggaagca attcttatac
      841 tacagatgtt attggtgacg gtgggattgt ttaccgtgtg ggtgagcaag gatatgtttc
      901 gtggggagct ggtaacgcta atccttatgc gcctgtacag attgaattac agcgcacata
      961 tgataaagca ttgtttgaaa aaaactatcg agcttatatt gaatatacaa gagatagtgc
     1021 aaaaaaatat ggaattccat tgactcttga tcaaggaact tctttattta caaaaggaat
     1081 catttctcat ttgtgggtga caaattatgt ttgggggaac cacacagatc catatggtta
     1141 cttatcgcaa atgggagtta gcaaagaaaa gcttgcttat gatttagctc atggatttac
     1201 cgatgaaaat ccaactactt cagatgataa accagtcatt gatccaacta gagcaggtgc
     1261 agcaaatcct acgctgacag atggaacaaa tcacgcccac attgatcagt ttggagaaat
     1321 cgaaaacgca aacttgcatg tggctggatg gcacattgct aattataaat acgagtatat
     1381 tttcattatg gattacaata ctggaaaaga attagctcga gtaagagctg atggaattta
     1441 tagaccagat gtaaatcaag cttataatac ttctggaaac gttggttatc atgtatcttt
     1501 caatatgcgt aattttccta ataagaaagt ctatgtaatg atgcgtgcaa cgaatgatcc
     1561 agaagggaac actaaaggcg gagcacaaga ttttcatgat aaacgctggt atttaaatat
     1621 tccgcaacga taaaaaaagc ccctcgat
//
LOCUS       DARPZF010000149         1622 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.159, whole genome shotgun sequence.
ACCESSION   DARPZF010000149 DARPZF010000000
VERSION     DARPZF010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1622
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.159"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            216..722
                     /locus_tag="SLE65_002907"
     CDS             216..722
                     /locus_tag="SLE65_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450127.1"
                     /translation="MDIKWLVQQNDSNLELAIKYLEETIFEDEHLTDNFLQVLKYLEI
                     YSVKKNKLIGENDSPIKTPIELSLRNRMGILQRSEIVKELFYHKFSYEIRLDDTYEHY
                     RIVFFVYNSIEDATATTALTFGFTKNGTINSDKTRQAATESDDICKKVCNGEENYWIG
                     EEKLNEIY"
     gene            709..1161
                     /locus_tag="SLE65_002908"
     CDS             709..1161
                     /locus_tag="SLE65_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450128.1"
                     /translation="MKSINDLLKKHPDLYKKLNSEQRNLSKQLLKIRLKKQKNVTEFS
                     KMLGISEKKYLEFEFGDMHIPVAEYNKLLKQVENLSYKDSMNFTIKVAGGPIKYDRIE
                     NKPYIRNKSYSVFKSRKRKEVSSNMVYASVNYQDTSRYIVEKEVYVHG"
     gene            1154..1552
                     /locus_tag="SLE65_002909"
     CDS             1154..1552
                     /locus_tag="SLE65_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450129.1"
                     /translation="MDKGNSVTFALENISLNKIHFELTDNFSYGDLEFNIELGYKEDE
                     AEYLEKKLVSLRAHIVGGMEGAPVDILLFSVIRVSTNEQPYKKLVEESMGELAKPILN
                     KASNLISNLYSEVGVMPTVIDLYQLYSQQK"
BASE COUNT          644 a          190 c          270 g          518 t
ORIGIN      
        1 cgtaaactag tttggtaata caattgtaat ttattttcag tatttaaaca tttctacctt
       61 attacattat gttaactaaa ttgcttataa aataagctaa tttttattga caagcaggat
      121 gtactatagt taaacttaaa ataagataca aatatatata atatgcttat acatatagta
      181 atatttacta atattgaaac aggtggttta gtgagatgga cattaagtgg ttggttcaac
      241 aaaatgatag caatttagaa ttggcgatta aatatctcga agaaactatc tttgaagatg
      301 aacatcttac agataatttt ttacaagtat taaaatatct tgaaatttac tctgttaaaa
      361 aaaataaatt aattggtgaa aatgattctc caataaaaac acctattgag ctaagcttaa
      421 gaaatcggat gggaatactc caaagatcgg aaatagtaaa agaacttttt tatcataaat
      481 ttagttatga aataagacta gatgatactt atgagcatta tagaattgtt tttttcgtat
      541 acaattctat agaagatgct actgcgacta ctgcattaac attcggtttt acgaaaaatg
      601 gaacaatcaa ttcggataaa acccgtcaag ctgctacaga aagtgatgat atatgtaaga
      661 aagtatgcaa tggggaagag aattactgga taggggagga aaagttgaat gaaatctatt
      721 aatgatttat taaaaaaaca tcctgattta tataaaaaat taaattctga acaaagaaac
      781 ctgtccaaac aattacttaa aataagatta aaaaaacaaa aaaacgtgac agaattctca
      841 aaaatgttag gaataagtga aaaaaaatat cttgaatttg agttcggaga tatgcatatt
      901 cctgttgcag agtacaataa acttttgaaa caagttgaaa atttgtccta taaagattca
      961 atgaatttca ctattaaggt tgctggcggc cctattaaat atgaccgtat tgaaaataaa
     1021 ccttatattc ggaataaaag ttactcagta tttaaaagta gaaagagaaa agaagtatcg
     1081 tcaaatatgg tctatgctag tgttaattac caagatacga gccgctatat tgtagaaaaa
     1141 gaggtatatg tacatggata aaggaaatag tgttactttt gcacttgaaa atattagttt
     1201 gaataaaatt cattttgaat taactgataa ttttagttat ggagatttag agtttaatat
     1261 tgaacttgga tataaagaag acgaagcaga gtatctagaa aaaaaacttg tttctttacg
     1321 agctcacatt gtagggggga tggaaggagc accggtagat attttactct tttcagttat
     1381 tcgtgtttct acaaatgaac agccatataa aaaattagta gaagaatcta tgggagagct
     1441 agctaaacct atcctgaata aagcttctaa tttgatttct aatttatata gcgaagtagg
     1501 agttatgcct acagttattg atttatatca gctatatagt caacaaaaat aaaatacaag
     1561 taatagagtt atctatttaa atttgcaaga caaagacctc aaccagtcat ccttggttga
     1621 gg
//
LOCUS       DARPZF010000150         1456 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.160, whole genome shotgun sequence.
ACCESSION   DARPZF010000150 DARPZF010000000
VERSION     DARPZF010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.160"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            108..1040
                     /locus_tag="SLE65_002910"
     CDS             108..1040
                     /locus_tag="SLE65_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEI8450130.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1112..>1456
                     /locus_tag="SLE65_002911"
     CDS             1112..>1456
                     /locus_tag="SLE65_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450131.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQD"
BASE COUNT          640 a          169 c          227 g          420 t
ORIGIN      
        1 atgaaataaa tcaaaagtat gatgaaacat taaaaaatgt ctattcttca cttatcgttt
       61 caaatataga agaaacttca tcttctgaaa taaaaaataa gctttctttg ttaaaattaa
      121 aagaaaagga atatattatt gacgatgctg tttctgtccc tcttatttta aataaacgag
      181 agaaaaataa tttaaagaaa aaaatgctca ttccatttga ttcagaagtg aaaggattac
      241 tcaataaact aactatttct aatatagact cgactaggga aaaaatcata aaaatatttg
      301 ataaaattaa taatttattc aagaatgaca atgctgaatt aaggaagggt cttttagagt
      361 ttaaacttca agaactagaa cttcattact cttatttagt gaaaattacc gaagaaaaag
      421 aacaacaaaa agcaataaaa gaacagatga tagaagagga aaaagttcgt agagaaattg
      481 atcgtgaaaa gaaacgtatt gataaagaac aacgtcaatt caattctgaa atttccaaat
      541 taatcgcata tatgcaaaaa gctaatgcag atgtggaaaa agaattatat gcaaataaaa
      601 ttcaagaact ggaagaaaaa ttaaaagaat tagaagttat acgtgaaaat gtattacaaa
      661 gagaattaaa tactagagcc ggttatgtgt atgtaattag taatattggg tcttttggtg
      721 aagacatata taaaattggt atgactagaa gattagaacc tatggataga ataaaagaat
      781 tgagtagtgc atcggttcca tttgaatttg acgttcatgc gatgattttt tcagaggacg
      841 ctccgtcttt ggaaactaaa ttgcataatc attttagaaa acaagaagtt aataaaatta
      901 atcaaagaaa agaatttttc aaagtttcac tagacgaaat agagaaagtt gttttagaaa
      961 attataatgg aacagtaaca tttacaaaat tagctaaagc tgaacaatat agacgatctt
     1021 tagaattgtc aaaagattaa atatataaaa agccttcggg ctttttcttt taacaattaa
     1081 taggaacgta tattcgaaag gaatagaaat aatgtggtta gaaaaaataa atgacaaaaa
     1141 atttaagtac accgaacgtt atacggatcc cttaactgaa aaaaagagaa aagtgtccgt
     1201 tactttatct agcaattcac gccaagcttg gaatcaagct aacttacttt tgaatgaaaa
     1261 aatcgcagaa aaaataaaac gaaatgaaga attaccacta acttttggag aattaaaaac
     1321 taaatgggat gaaaaataca agccaactgt aaaagaaagt tcctatcgaa caactcaggt
     1381 ttatctatca ttaatttcaa aatatataaa agatgatgta cttgtaaaaa acgttaatag
     1441 taatcttata caagat
//
LOCUS       DARPZF010000151         1415 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.161, whole genome shotgun sequence.
ACCESSION   DARPZF010000151 DARPZF010000000
VERSION     DARPZF010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.161"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            90..1382
                     /locus_tag="SLE65_002912"
     CDS             90..1382
                     /locus_tag="SLE65_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEI8450132.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
BASE COUNT          460 a          288 c          256 g          411 t
ORIGIN      
        1 atctttttta ttttccaaaa catatagaaa agacaccttg aaatccttta gaattaattt
       61 ggcgaaccaa cccaaaagga ggaatcaaga tgtcttacac tcaccttatc aaagaaacat
      121 tagatattct agacttatca gttactttta acgaaaattg tctcacaaaa gaaaaataca
      181 aagggcaaat ctgtcatatt tatcgtggaa acttgattta tacagcccaa gaatgcatcc
      241 actgtaaaca ccagattgct tcagatattg tgcgttgggg tacaacaacc gtccggttgt
      301 taatgaacga tgtttctgaa taccgtacct acctcgaatt gaaaaagcaa cgcttcaaat
      361 gcaaagcttg tcagcggacc tttgtcgcag atacttctgt tgcgaaaaaa cattgtttca
      421 tcagtgagaa agtccgctgg tctgtcgtga ctcgtctgaa aaaaaatacc tcaatgacag
      481 agatcgccgc tcagaaaaat ctatcggtct cttctgttta ccgtattatg aagcgatttt
      541 atcgtccgtt gaatcctttt cggacaccgt tacctaaggt actttgtttt gatgaattca
      601 aatcagttcg gggtgtttca ggtgctatga gtttcatcat gatggatgga caaacacagc
      661 gcttattgga cattgtcgag aaccgacaac tgcctttttt aaaacgttat tttagtcatt
      721 tttcacgaga aattcgtgaa gcggtcgaat ggatcgtgat tgatatgtac gctccttatg
      781 tatcgctcgt taaaaagctg tttccaaaag cacagctgat tattgaccgg tttcacatcg
      841 tccaacatat tggtcgtacc tttcgcaatc atcgaatcaa agaaacgaac caactattaa
      901 aaagcaaaga acaaaaacac tatcaattag gtaagcaatt aaaaagatac tggaaacttc
      961 ttcaaaaaga tgaacgcaag cttgattata ctcgacgcct ttggcgacct ggcttcaaag
     1021 ctcatttaac agagaccgat attgtggatc gcttactgaa agggagccct gctttgcgtg
     1081 taggctatca gttatatcaa gactttcttt acgctgtaaa ggaacgagac tacgtatcgt
     1141 ttgaagaact acttaccaat aatatcatgc ttcccgaagg ctatcagacg accttgagaa
     1201 cgttccagaa atttctgcca caaatcaaaa atgctttaca acaaagttat tcaaatggcc
     1261 cacttgaatg tctgaacaac catatcaaag tgttaaaacg aaatgcatat ggctttcgta
     1321 gcttttataa tttcaaattg cgcatcatga ttcgtcatgg caacgcattg attttcaact
     1381 aaaaaagatc aagaggaact gatccacttg atctc
//
LOCUS       DARPZF010000152         1394 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.162, whole genome shotgun sequence.
ACCESSION   DARPZF010000152 DARPZF010000000
VERSION     DARPZF010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1394
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.162"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..397
                     /locus_tag="SLE65_002913"
     CDS             <1..397
                     /locus_tag="SLE65_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450133.1"
                     /translation="HWNAIEGKPTTVKGDKGDPGQAATITIGTVSSGSTASVTNVGTS
                     SAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDKTKLDGIAAGAQKNPGNAT
                     TTTAGLMSATDKVKLDGLANITFEKVGTV"
     gene            397..891
                     /locus_tag="SLE65_002914"
     CDS             397..891
                     /locus_tag="SLE65_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450134.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     ESVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            905..1336
                     /locus_tag="SLE65_002915"
     CDS             905..1336
                     /locus_tag="SLE65_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450135.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
BASE COUNT          513 a          214 c          307 g          360 t
ORIGIN      
        1 tcattggaat gctatagaag gcaaaccaac aacggtgaag ggagataaag gcgatcctgg
       61 ccaagcagca acaattacca taggaaccgt ttctagtggt tcaaccgctt ctgttacgaa
      121 tgtaggaaca tcatctgcag ctagatttaa ttttgtttta ccaaagggag ataaaggtga
      181 tcctggaata aatgccacaa ctacagctgt agctacaact acagcaaatg ggttgatgtc
      241 gtccacagat aaaactaagt tggatggaat tgcagctgga gcacagaaaa atccaggtaa
      301 tgctacaact acgacagcag gtttaatgtc agcaaccgat aaagtgaaac ttgatggatt
      361 agcgaatatt acatttgaga aagtggggac ggtttaatgg ctgatattgt tcaattaaaa
      421 gaagacggag ttgctaaata cttaaaaacg catgtagaag ctattgatgg taaagaagca
      481 ttggtgcaga cagatggaga ccaagccatt gcaggacata agaatttttc aggttctgta
      541 acaatcaata ataaacgtgt tttgacgact gatgataaca gatatgaagt ggtaaatctg
      601 gttgtcacta acggtaatac agggacagca aagctttatc gtgaaggaaa aacagtttct
      661 atatattttg tggctttaaa cggaaaaagt agtggcggga atgagtcggt tattttaact
      721 gttccagaag gctatcggac accaattagt tttgaacaac tggttgggtc aatagaccgt
      781 tctactttga acagtgctca actatctatt ggcgcagacg gagccattaa atggagaaga
      841 aattcaagtt atggatcagc ttattcattt gttatcactt attcaattta agggaggaaa
      901 tctaatgaaa gtagtttaca aatcaatcaa gccttacgga ttcgagcaaa tcattttgaa
      961 caatcaagaa aatatccctg aaaactgtac agagattaaa ccaccagttc ctaactggag
     1021 accaagattt gattttgata aaaaacagtg ggttgagtta gctactgaag aagagaaaaa
     1081 agggaatgct gttgatagcg tagatgaatt ggctaatatt aaggcattat acgaaacgct
     1141 gaaggcagaa aatgatgaat tgaaacagct aaattctaaa gcaatgctaa acaatgtagc
     1201 aatcaagcaa gaaaatgtct tattgaaaga aaagtcagaa agtttagcgc agttgaattc
     1261 aaaaacgatg cttgcttctg tacaaaatac caaggaaatc gaagaaatca aaaaacaatt
     1321 acaaggtggg aagtaacatg tattcatatg aagatatcaa actaatgtat gactggggct
     1381 gtttcactaa cgaa
//
LOCUS       DARPZF010000153         1372 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.163, whole genome shotgun sequence.
ACCESSION   DARPZF010000153 DARPZF010000000
VERSION     DARPZF010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.163"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            11..1350
                     /locus_tag="SLE65_002916"
     CDS             join(11..452,452..1350)
                     /locus_tag="SLE65_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HEI8450136.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          568 a          179 c          240 g          385 t
ORIGIN      
        1 ggtgcttttt ttgcggaaat atacatttgt ttttaagaaa aaagtagttt cagactattt
       61 aaataacgaa ggcggctaca aatatcttgc acataaatat caaataaatc gtacactggt
      121 tagacattgg gtaaggattt ataactatca tggttgggaa ggcttggttg gaggtggcaa
      181 aagctacact acaaaattta aacttgatgt tatagaatat atggaaacaa atggtctttc
      241 tatccaagaa actgctaaaa aatttaatat cggttcaaat agaactctaa gtaaatggat
      301 agagcaatat gaagaaggcg gtgcttcttc acttgagagc caaaaaaggg gcagaaaaat
      361 tagtatgaat tccaagctaa acattcctaa aaaacttaaa gatgagtctc ttgaagaaga
      421 agttattcgt ttaagagcag agaacgcata tttaaaaaag ttagaaacct tgattcaaga
      481 acaagatttg agcaagaaga aatcaaggtt aaaacaatcc ttcagctcaa aaaagaattt
      541 aaattgaatc tattactttc aattgcacaa ttagcgaagt caacttatta ttactgggta
      601 aaaaaattag ataagccaga taaatatagc aagataaagc aagaaattac agcgattgta
      661 aaagaatcaa gaaactctta tggttatcgt agagtcactt tagcgttaaa gatgaaagga
      721 tatacaatca atcataaaac agttagaaaa ttaatgtccc aaatgggact tacctgtcaa
      781 atccgaataa agcgatataa atcttataaa ggaacagtag gaaaaattgc caagaatgtg
      841 ttaaaacgaa atttttcagt agatacaccc aataaaaaat gggtgacaga cgtcactgaa
      901 ttcaagataa aaggaagaaa aatctatcta tctcctatac ttgatttatt taacggagaa
      961 ataattagtt atagtatatc aactagtcca acatataaac tgattgaaga aatgcttcaa
     1021 caagcaatta aaaaaaaggg aactgagggt tcactgattc tacattcaga tcaaggatgg
     1081 cagtatcaga tgccacaata tcaaaaaaaa ttaaaagaga ataacattat tcaaagcatg
     1141 tctagaaaag gaaattgctt agataattct gtaatagaaa atttttttgg tgtgcttaaa
     1201 tcagagtttt tttatcgaga aaaattccga tcaattgaga tatttcaaag taaattaaat
     1261 gagtatatta ggtggtataa taacaaaagg ataaaactaa agttaaatgg actatctcca
     1321 gtagaatatc ggaaacagtc cattaaatag ttcaactttt ggggttcagt tc
//
LOCUS       DARPZF010000154         1369 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.164, whole genome shotgun sequence.
ACCESSION   DARPZF010000154 DARPZF010000000
VERSION     DARPZF010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1369
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.164"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            39..1340
                     /locus_tag="SLE65_002917"
     CDS             39..1340
                     /locus_tag="SLE65_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEI8450137.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          447 a          274 c          253 g          395 t
ORIGIN      
        1 aattgaatca ccacaacaca atcaaaggag cgttctgtat gcctgatctt catcatatca
       61 aactactact tggaatcaaa gataaaaaca ttttcatcac aaatgtggaa tcgaagagca
      121 ttaagaatat caagagtctt gttgtttctg cgacgttaag taaagaaatt cgtcgctgtc
      181 ctttgtgtaa acagatgaat catgaaggca tgatcgttaa gaacggaaag aaaaaatcgc
      241 tcattcaact taataaatgt gcgaaccaac tgacttatct tgctttagcg aaacaacgct
      301 accactgtcg tggctgccac acctatttta cggcgaatac ctacattgtc gatagaaact
      361 gctttatcgc taaacaagtg cgctataaaa ttttagaaga gctaactgaa aaacaagcaa
      421 tgacgacaat tgctaagcat tgcggcgttt cttggtcgac cgtttctcgg acactcgctt
      481 ctctgatccc catgacaaaa gtaaaaagaa attggttacc gcgttgttta ttaatggatg
      541 aatttcgttc actgaaaaat caagtcggtc cctactcctt ttcttgtatg gatggcgata
      601 ctggaaaatt actggatatt cttccttcac ggaagaaaaa ggctctcgtt tcttatttta
      661 tgcaatttga acgacgcgca cgattgaagg taaaggtcat cgtgacggac atgaatgttt
      721 cttatgcctc tctgataaag gaatgttttc caaaggcaaa actcgttgtg gatcgttttc
      781 acattgtcaa acatctcatt cgtaaatttg aggatattcg cgtacgaatc atgaaaagct
      841 ttgatcgaaa cgatccaaca caagccaaat attatcgaca attaaaggcg ttgtctcggc
      901 ttctgatcaa acgacaggac aagcttgttt atgacaaatg gaccaaatgg cgcaattttg
      961 gttgggcgta tctcaccgaa agtgaagtgg tggatcgtct gctttcgatc tctgacgaat
     1021 tacgaatcgc ctatttttac tatcaagaaa ttcttcaagc gtttcacgac aaagaggcgg
     1081 acactttctt taaacttgta agaacgatgc ccaattccgt tccaaaagaa ctgcattcta
     1141 taaaaaaagc ttttataaac tatgaatccg gcattcgttt agccctcgaa ttgccttatt
     1201 caaatgccaa aatagaaaat ctgcataccc acatcaaagc attgaaacga gtcgcttatg
     1261 gctttcgaag ctttcggaaa atgaagacca gaattttctt actaaataat ctgattacct
     1321 atgaatcaaa aaacatctaa agtagaaaag gaattctacc ttagatgtt
//
LOCUS       DARPZF010000155         1354 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.165, whole genome shotgun sequence.
ACCESSION   DARPZF010000155 DARPZF010000000
VERSION     DARPZF010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1354
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.165"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            82..>1354
                     /locus_tag="SLE65_002918"
     CDS             82..>1354
                     /locus_tag="SLE65_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HEI8450138.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLI"
BASE COUNT          460 a          261 c          257 g          376 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atca
//
LOCUS       DARPZF010000156         1348 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.166, whole genome shotgun sequence.
ACCESSION   DARPZF010000156 DARPZF010000000
VERSION     DARPZF010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1348
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.166"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            15..1310
                     /locus_tag="SLE65_002919"
     CDS             15..1310
                     /locus_tag="SLE65_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEI8450139.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          418 a          268 c          260 g          402 t
ORIGIN      
        1 taggaggatt caagatgtct catactcagc ttatcaaaga taccctaaat attctagacc
       61 taaatatcta tttcgaggaa aattgtttaa ctaaagaaaa atacaaaggg caaatttgct
      121 tgatttacaa aggaactctt ctgtacaagc cagaagagtg ttcccattgt ctttgtgtcg
      181 tcccctctag gatcattcgt tgggggacga caaccgttcg gttgttactg aatgatgtgt
      241 ctgagtatcg cacttatctg gagctgaaga aacaacgatt taaatgtaag tcttgccaaa
      301 gaacattcgt agcggatacc tctgttgctg aaaaacactg tttcattagt caaaaagttc
      361 gttggtctgt cattgctcgc ttaaaagaga atacttccat gacggaaatc gctcgtcaga
      421 aaaatatttc cacttcttcg gtctatcgtg tcatgaagcg attctaccgc ccattgaatc
      481 ctttcaaaca gactttgcca aaggtcttat gctttgatga attcaaatcg gttcgaagtg
      541 ttgccagtgc aatgagtttt atcatgatgg acggacaaag ccatgcatta ttggatattg
      601 tcgaaaatcg acgcttgcct tatttagaac gctatttttc tcggttttca ttagcgactc
      661 gtgaagccgt tcaattgatt gttattgata tgtatgcgcc ttatgtttcg ttggtgaaaa
      721 agcttttccc gaatgctcag ttgatcatcg atcgtttcca catcgtccaa catattggca
      781 gaactttctt gaatcatcga gtgaaagaaa ccacggtacg acttaaagga aattcccact
      841 ctcaacgagg gttagggaaa aaattgaagc gctattggaa actcctacaa aaagaagaag
      901 caaagttaaa ctatgaaaaa cgggtttggc gtgccagttt taaagattat ttgactgaaa
      961 gtgagattgc cgatcgactg ttagctgctt gtcccaactt acgccaaggc tatcagttat
     1021 accaagacat tctttatgcg gtaaagaaaa gagatcagtc actatttgag gattgtttaa
     1081 ctagagacat tagcggtctg ccagaaacct atacaaccac tttacgaacg tttaaaaagt
     1141 ttctgccaca gatccaaaat gcgcttcact acagctattc aaacggacca ttggaatgct
     1201 taaacaacca catcaaagta ttaaaacgca atgcgtacgg ctttcgcaac ttttacaatt
     1261 tcaaactacg aattatgatt cgtcatggca aaacattttt aaccaaataa acagaacaga
     1321 aagaggtttt cttctttctg ttctgtcc
//
LOCUS       DARPZF010000157         1347 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.167, whole genome shotgun sequence.
ACCESSION   DARPZF010000157 DARPZF010000000
VERSION     DARPZF010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.167"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            14..880
                     /locus_tag="SLE65_002920"
     CDS             14..880
                     /locus_tag="SLE65_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEI8450140.1"
                     /translation="MRDVGDKKVQFTFEQLKDLSNYKATANVRFIDDLETTYDKLMDL
                     RFGRRSADGLQRERFVLFNQFKIDGKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQF
                     NELESSYSKTMFRLLKQYRTKGIAYFSKEDFHELLDIPKSYRESDINKKIIKPIRQEL
                     TAIFKGLTIQKRYGKGRGKPVIGYQFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQ
                     VQSEKAPTSLQEKIKEQKRKLELLQQLEKLEREQNTQNKENNAQKSEINSDIPSELKK
                     DLLDNLQNLFKD"
     gene            897..>1347
                     /locus_tag="SLE65_002921"
     CDS             897..>1347
                     /locus_tag="SLE65_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEI8450141.1"
                     /translation="MTEKTIKELAEELGVSKTAINKKVSDENRKLWFSKIGNKFVINE
                     TGQKAIKSMFFNENENSNQQLVGEKTKTENHKNANQVPELEVLSLLEQQLNQKDMQLQ
                     EKDEQIKQMQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENKST"
BASE COUNT          596 a          228 c          202 g          321 t
ORIGIN      
        1 tatagtatct agaatgcgtg acgtaggcga taaaaaagta caatttacat tcgaacaatt
       61 aaaagattta agcaattata aagcaactgc aaatgttcga ttcatagatg atttagaaac
      121 aacgtatgac aaattaatgg atttacgttt tggtagaaga agtgctgacg gtttgcaacg
      181 tgaacgattt gttttattta atcaatttaa aatcgatgga aaagctgata ttccttttgc
      241 tgaaatacaa gtccatgaga aagccttacc cttacttaat aatcttgaag aatgggttcg
      301 atattctctc caacaattca atgaattaga aagcagttat tccaaaacca tgtttagatt
      361 attaaaacaa tacagaacca aaggaattgc ctatttttca aaagaagact ttcatgaatt
      421 acttgatatc cctaaaagtt atagagaaag tgatataaat aaaaaaatta taaagcctat
      481 tcgccaagaa ctaaccgcaa tcttcaaagg tctgacaatc caaaagagat acggaaaagg
      541 acggggaaag cctgtcattg gctatcaatt tacatttaaa cctgagataa aaaaatcaga
      601 cgactttaac aaacatgccc caacaaaaga agaacaaaac aaagcattag aactagctaa
      661 ccaacaagtt caatctgaaa aagcacctac ttcattacaa gaaaaaatca aagaacaaaa
      721 gcgaaaattg gaacttttac aacagttaga aaagttagaa agagaacaaa atacccaaaa
      781 taaagaaaat aatgcacaaa aatcagagat aaattccgat attccttcag aactaaaaaa
      841 agacttatta gacaatcttc aaaacttatt caaagattga ggggttttta gattttatga
      901 cagaaaaaac aatcaaagaa cttgctgaag aattaggagt tagtaaaaca gcaattaaca
      961 aaaaagtttc tgacgaaaat cgaaaacttt ggttttcgaa aatcggaaac aagtttgtga
     1021 ttaatgaaac cggacaaaag gctataaaat caatgttttt taacgaaaac gaaaactcaa
     1081 atcaacaact agttggcgaa aaaactaaaa ccgaaaacca caaaaacgcc aaccaagttc
     1141 ccgaattaga agtcctttct ctcctagaac aacagttaaa tcaaaaagat atgcaactac
     1201 aagaaaaaga cgagcaaata aaacaaatgc aaaaattact cgaccaacaa caacaactca
     1261 ccctgcaagc caaccaacaa atcgagaaac tgcaggaaca actacagttg acttatacgg
     1321 aagaatcttc ggaaaataaa tcaacga
//
LOCUS       DARPZF010000158         1309 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.168, whole genome shotgun sequence.
ACCESSION   DARPZF010000158 DARPZF010000000
VERSION     DARPZF010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.168"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            242..315
                     /locus_tag="SLE65_002922"
     tRNA            242..315
                     /locus_tag="SLE65_002922"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:276..278,aa:Ile,seq:cat)
     gene            695..856
                     /locus_tag="SLE65_002923"
                     /pseudo
     CDS             695..856
                     /locus_tag="SLE65_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
     gene            1006..1206
                     /locus_tag="SLE65_002924"
     CDS             1006..1206
                     /locus_tag="SLE65_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEI8450142.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT          419 a          208 c          267 g          415 t
ORIGIN      
        1 cttttttgct ctgtaattaa ctcgtataga tcctgcaaga tagtttgttt ctgaataaat
       61 gattgatatg aagtatttag atgactgtat tgacaactat aaaaatcatt cgataaaata
      121 gtgatgttat cgcatatctt cactatcacc cataatagtc acactccaag ctatgcgata
      181 acaggattgt tgccacacct tctactggtt gattgtttat ggctttatgt ggcaacaacc
      241 tgtactctta gctcagttgg tcagagcaga cggctcataa ccgtccggtc gtaggttcga
      301 gtcctacagg gtacataatt taatctattt gataaaaaat aaaattcaat aatggtataa
      361 taaaatgtcg gctcgtcgct tccacagaga ttttcgtggg aggaggtgta tgatttgttt
      421 gaattcactt tggagcacgt gctcttgcca ttgttaattg gtttaacttt ggcattattt
      481 agtcattggc tagataaaca ttagagccga caatggcgct tactgtttcg cagcggtaag
      541 cgtctttttt tgaaaaagaa aaaaacacaa cgtattcgca ggtacgttgt gtttatggtg
      601 tatatttgtt taaattcact ttcaattatt attatacttg ttaaataaat tgtgtcaata
      661 taaaagatat ttttatacgt gtactaacct atattatcct tctggtaatg ttattccatc
      721 gcagcaggat atgaatttta ccaaaaggat acaaaagtgt ggagaaatga tggggatcac
      781 tgtactggac cacttgatca tcggacgcaa acgatatttt agtttgagag aagaaggaat
      841 gatggaagag aagtaagttg ctttcttgca aaaaaaatga agcaagtgta caattatatt
      901 gtaattttgt ttgggaatag aagttgaaac atctgttgca cctctatcgt acacgagcaa
      961 tgttacaatt taaattagtg cttttggcac gaggaggata ttattatgga aaacggaaca
     1021 gtaaaatggt tcaacgctga aaaaggattt ggatttatct cacgtgaaga tggaagcgac
     1081 gtattcgttc acttctcagc tatccaaggt gacggattca aaacattaga agaaggtcaa
     1141 gcagtgactt tcgacgttga agaatcagac cgcggcccac aagctgcaaa cgttgtaaaa
     1201 gcttaatttt atctgtaaat caaattgatg gtagacatca atttttacga gagaacaaag
     1261 cgagtaacaa aaatacctgc cacaagagac aatttctctt gtggcaggt
//
LOCUS       DARPZF010000159         1302 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.169, whole genome shotgun sequence.
ACCESSION   DARPZF010000159 DARPZF010000000
VERSION     DARPZF010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1302
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.169"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..848
                     /locus_tag="SLE65_002925"
     CDS             <1..848
                     /locus_tag="SLE65_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEI8450143.1"
                     /translation="EIADLIEKMYGHHYTPQTMSNITKSFTEEVTAFKGRELHDRYAA
                     IYMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQER
                     GLKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVFRNISHKVRVNNRKEVCDDFKM
                     VYQASSKEVALEARGAFAKKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLI
                     ESFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLS
                     QPMEN"
BASE COUNT          424 a          238 c          254 g          386 t
ORIGIN      
        1 ctgaaattgc tgatttgatc gaaaaaatgt acggtcatca ctatactcca caaaccatgt
       61 ccaatataac aaaatcattt acagaagagg taacggcgtt taaagggcga gagcttcatg
      121 accgttatgc tgctatttat atggacgcaa cgtatattcc gttaaagcgg aaaaccgtcg
      181 ccaaggaagc tattcatatc gcagttggca ttcgcccgga cggatcaaag gaagtattga
      241 gctatgcgat tgcaccgact gaatccatca cgatttggga ggaaatttta ttagaccttc
      301 aagagcgcgg tttgaaaaat gtcctcctgt tcatcacgga tggcttaaag gggatggtag
      361 gagcgattag tcggttctat cccaaagctc gttttcaaca ttgttgtgta cacgtttttc
      421 gtaatatcag tcacaaagtg cgtgtcaata atcgtaagga agtctgtgat gattttaaaa
      481 tggtgtatca agcctcatct aaagaggtgg cgttagaagc acgtggtgct tttgcgaaaa
      541 aatggaaaac cagctatcca aaagtggttg aatcgattct ttcgaacgat cacttgctca
      601 ctttctatga tttccccttg gccatacgca agagtattta ttctacgaac ttgattgaat
      661 cctttaataa gcaaatcaag aaatacagcc accgcaagga acagttccaa aacgaagagt
      721 cgatggaacg tttcttagtc tcgtcttttg atacttacaa ccaaaaattc ctaggtcgca
      781 gtcataaagg tttccaacag gccgaaggcg agctcgaaca aatgctgagt caaccgatgg
      841 agaattagaa acaatctaca gtagggaaga accatttaca caaaattatt gacgctccca
      901 agctaaaact cctattaatc gatctactaa aaataaataa aaaaattctt ttcaatttta
      961 tttatggtat gacataaata aagtaaagtt attcttctag gttaatctta ttaatactct
     1021 ttctcactag tgttgcatgc aacactagtg agaaagagta ttaaatatac tgcaaggcaa
     1081 gacatttggt aattgaagaa taacaagcaa aaaaatagca gtcaggtctc ttgacaaagt
     1141 atagttgcta ttcttttttt aggccctact ttaatgaaat ttttgtttgg agggaacgac
     1201 ttcattcctt tgattatttc agttgaattt aatagagaag cctggcgtct attaagaaat
     1261 acttttcttg atgagcgtca atttttttaa cggaaatcta tc
//
LOCUS       DARPZF010000160         1298 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.170, whole genome shotgun sequence.
ACCESSION   DARPZF010000160 DARPZF010000000
VERSION     DARPZF010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1298
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.170"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
BASE COUNT          355 a          234 c          247 g          462 t
ORIGIN      
        1 taggtggaat tctatgatta actgttttaa ctttatattt tctatttgat gtcttcataa
       61 gaatcttctt tcttaaaaaa atataaaaaa aaagccctac cataatgcgc atgatattaa
      121 atcagaggcg tggcaagtac tgatagatat attaaaacac atttgaatta aactgtaaag
      181 cttttttatt taaaaattta gttgtcaaaa tcgtgatttt ttttaagtgt gcaaccaaaa
      241 gaaatgccta tatatcaagc attactacca taatttttca cattattccc cccctgttag
      301 aatgcggggg gctaaatgcg atcggtctat cgagcttgct cgatagacct ttttttgctt
      361 ggaaatggcg caaaaccggt gcctttcacg aatttgtaag cttgtttgta cacgtctcgc
      421 tctaggagac cttgttcgct ccgcaccgca agcagctttt agcaacagca cttttttgct
      481 aacgtacgaa aatggctcct ccggaattct gctgaatcgg ttgcttattg ttttgtttca
      541 tacgctctta tttgcgtttt cagacgtttt actacccaag gtatataaaa tatacaagaa
      601 catagataag acagattaaa tcgaatttta ggatggtttt atgctcttta agggttgtta
      661 gggcttgccc tgaccgcctg taaggtgctt taagaacaag ataagggtta tccatactaa
      721 actgtcttaa aacggcttaa acgagcgcgc agagcctcta aaaaaatctc tttaaacaac
      781 gtttttagca aaggagcctt taggcgactg cgcaggtaca atgtgagggt gtttttccct
      841 cacacctttt tagcgaccag agggagcaag tttcccagtt tagtaaaatt cgcgaacctg
      901 tttggctaaa aaagcagaaa atttttaggc gggaaatttt gcccctctcc tcttttataa
      961 tctcttttta aacctctttt taaacctctt taccgtcggc tgtatgctta ctctcccaag
     1021 gtgtgcagaa tcttttgggg gtctttttgt ctgtttttag gggtcttttt gtctgttttt
     1081 aggggtcttt ttgtctgttt ttgggggtct ttttgtctgt ttttaggggt ctttaattag
     1141 gggcttgacc cctattagaa agctctttat aattttgtta agtagttaat cttgaaggag
     1201 gattttatgg caaatgaaat tgtgaaatac caccatgaat taaatacgat tcctttacgc
     1261 aaatttacgt cagtagaaat gaatttattc ttctctat
//
LOCUS       DARPZF010000161         1294 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.171, whole genome shotgun sequence.
ACCESSION   DARPZF010000161 DARPZF010000000
VERSION     DARPZF010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.171"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..1244
                     /locus_tag="SLE65_002926"
     CDS             <1..1244
                     /locus_tag="SLE65_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HEI8450144.1"
                     /translation="ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCL
                     THYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQE
                     NYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESA
                     KTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESV
                     RLVYCFAHVRRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQ
                     QELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERN
                     IKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLS
                     AETLDQLLPWNKDVQQHFSRN"
BASE COUNT          423 a          233 c          277 g          361 t
ORIGIN      
        1 ctataacaga gaaagaacat ctccttcctt tggaagaaca attttgtgaa cattgcggtt
       61 cacagatgaa agatatcgga cggacaaaag tacgagaaga aattcgtttc catcaggcta
      121 tgttggattg tctcacccat tatcaacata cctattgttg taaaagctgc gaaaaagaag
      181 gactttcttc ttttaaaaaa gcgatcgttc ctaaaccttt gatttctaat agcttaggtt
      241 ccaatagttt agtggcggaa acgatccgga tgaaatttgg tcagaaagtt cctgcctatc
      301 ggcaagagaa ctattggaaa caaacacatg ggttggatat ttcgagagat aatatcacca
      361 attggcatat taaagcagtg caaaacgcgt tagacccttt aggagaacga ttaagagtct
      421 atcttaatca agaagagatt ctacacgggg atgaaacaag ttatcgtgtg attgaaagtg
      481 ccaaaacaga tacctattac tggcagtttt gtacaggaaa agacagtcag catcccatcg
      541 tttattatca ccacgacgaa agtcgtgctg gagatgttcc gaaaactttt ctcaaggagt
      601 ttacagggta tttacactgt gacggctata gcgggtataa tgccgtggaa agtgtacgac
      661 ttgtctattg tttcgcgcat gttcggcgga aatttttcga agcaattcca aaaggaaaga
      721 aaaacacgga tattcccgca gctcaagcag tcaaacaatt ggataaatgg tttgtcctag
      781 aaaagaaatg gaaagacttt tctcctgaga agcgattaag ctgtcggcaa caagaactgc
      841 gtccattatt tattgctttt tatgagtgga tggcaacgat agatcctgtt gcaaaatcca
      901 agttggatgc agccgttcaa tatgcgtgta aactacgaag tggttttgaa cctatttttg
      961 aagatggtcg tttagaactc acaaataatc gtgcggagcg aaatatcaaa gagctggtga
     1021 taggacggaa aaattggttg cattccacaa gtcttgaagg agcacgaact tcaggaatca
     1081 ttctgagtgt atataaaaca gcagaactta acggattgaa tcctgtaaag tatctagagt
     1141 ttctatttga taagatacca aatcttcccg tactttcagc agaaacttta gatcaactgt
     1201 tgccttggaa caaggatgta caacaacatt tttctcgtaa ctaaaaacgc caaacattcc
     1261 cgattctatt ctataggtcg ggttatttga cgta
//
LOCUS       DARPZF010000162         1290 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.172, whole genome shotgun sequence.
ACCESSION   DARPZF010000162 DARPZF010000000
VERSION     DARPZF010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.172"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..>1290
                     /locus_tag="SLE65_002927"
     rRNA            <1..>1290
                     /locus_tag="SLE65_002927"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          344 a          286 c          392 g          268 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagctg tccttagtac gagaggaccg ggatggactt accgctggtg taccagttgt
     1141 tctgccaagg gcattgctgg gtagctatgt agggaaggga taaacgctga aagcatctaa
     1201 gtgtgaagcc cacctcaaga tgagatttcc catttcttta agaaagtaag atccctgaga
     1261 gatgatcagg tagataggtc aggagtggaa
//
LOCUS       DARPZF010000163         1258 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.173, whole genome shotgun sequence.
ACCESSION   DARPZF010000163 DARPZF010000000
VERSION     DARPZF010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.173"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..1171)
                     /locus_tag="SLE65_002928"
     CDS             complement(<1..1171)
                     /locus_tag="SLE65_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HEI8450145.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEF"
BASE COUNT          367 a          273 c          211 g          407 t
ORIGIN      
        1 taaattctaa atattttcgt ggagaagcca gccactcagt gtctttttcc atcaaaagtg
       61 ttccaattat ccgagtgatg gaattgatat ttggaaaaat ccgaatcact cgttctctcc
      121 ggcgaatctc ttcgttcaac cgttccaaca cattggttgt acgaatcctt cggcggatat
      181 tttcaggaaa agacaaaatt tgaatagcat cttcaaagcc gttttctaaa atgtcgcaag
      241 cagcacttaa ttttgaatca caaccatatt tttccaagaa gtgctctttt ctttcacgtg
      301 tcaattcaag ttcagaggct ttaaagatac tcttcaactc gtcttttaca tcagaagaaa
      361 ctttctttgg cagcttatca aaaatatttc tcaaaaagtg ggcttggcat ctttgccagc
      421 tcgcacctaa aaagttcttg cgaacagcct taactaaccc tttgtgtgca tcagaaatga
      481 ccagttttac accgaacaaa cctcgttgaa cgaacgattg aaaaacggta tcccaattat
      541 cttccgattc gccgtcttga acatcaaaac caagaatcgt acgtcgtcca tcagaatcaa
      601 tgccgatacc aatatataca ccttttgaga caatacgatg attttccctt actttcatat
      661 acagggcatc acacatgaaa aatggatatt ccgagccttc taggctccgg tttctccact
      721 caaaaacaaa tggatccaac tgtttcatca gatttgaaac gaatgattta gaaacagtcg
      781 caccatccgt tagcagttca actgttttag ttactttgcg agtggagaca ccagaaatga
      841 ccatttcaat catggcagcg atcaaagctt tttcgcttcg ctgatatctt tcaaagatag
      901 taggactaaa cttaccgtct ctggttcgtg gaacatgaag ttctaacgta ccaattcgag
      961 ttgtaaacga acgatcgtag taaccatttc tttgtgattg ccgttcttct gaacgttcat
     1021 aggcatttgc ctgaatatat tgatttcgtt gttcttccat cagctgatta aacatgatag
     1081 tcataagtgt ttttgcggta tcattcgcac cgctttcgtt tataattgct tgaatttctt
     1141 cgctttcaaa agtaaaatgt acttgagtca ttgatatcag tcctattcga gtatgttttc
     1201 tgcaaaaaac attgtactcc taactgagat caatggcttt tttgatgctt cactttta
//
LOCUS       DARPZF010000164         1091 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.174, whole genome shotgun sequence.
ACCESSION   DARPZF010000164 DARPZF010000000
VERSION     DARPZF010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.174"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="SLE65_002929"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="SLE65_002929"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HEI8450146.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          384 a          135 c          187 g          385 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaaact aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgatga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta a
//
LOCUS       DARPZF010000165         1062 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.175, whole genome shotgun sequence.
ACCESSION   DARPZF010000165 DARPZF010000000
VERSION     DARPZF010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.175"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(37..993)
                     /locus_tag="SLE65_002930"
     CDS             complement(37..993)
                     /locus_tag="SLE65_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450147.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgtc aa
//
LOCUS       DARPZF010000166         1005 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.176, whole genome shotgun sequence.
ACCESSION   DARPZF010000166 DARPZF010000000
VERSION     DARPZF010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.176"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(128..775)
                     /locus_tag="SLE65_002931"
     CDS             complement(128..775)
                     /locus_tag="SLE65_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HEI8450148.1"
                     /translation="MEQTIKPYQYFFIIREVEQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILDHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
BASE COUNT          280 a          192 c          167 g          366 t
ORIGIN      
        1 agaaaggggc tgtccccaga ctttagtagg cgtcattagc tatctttcgt tagcatttaa
       61 aggcgaacac catcacctat tcacttccat taaaagatag catatttttc tgtaaaaaac
      121 aataaaatta tcgttctttc tttacacgtt cagcaaattc atagaaagga gccaatttcg
      181 ttaactgttg attacattgg tcactatcat gacaaatata attccccttt ttcgtatacg
      241 tgccatcaga acctgctttc gttgtagaaa gaaaaagcga aacattcgat gttttctgac
      301 agattgcaca gattccctta tttatcgttg gtgataaagt accgctaatc ccttttaatt
      361 tttcatcttc gtaatagacc atgaattttt tctgcgtacc tggatcattc cagccgatgt
      421 acgtatgttc ttgcaagtcg atttcattcc aagctggttg tttgagtttt ttcacttttc
      481 ggaataattt ctcgatttgt ggtttgctag gctgcataaa cggctgaacg atttgcttca
      541 gctcctccaa tgctctttct gcttgcgctt ttgtcagttt tacgtctaaa actgtcgtta
      601 aaaatgtatc gatttctggc agttcgtgat ctaatatgtc tcgaatcttt tcagctgcta
      661 gtgcctgaac tgtttgtacc gtttttggat cattgacaga tgagtacgca tttaataact
      721 gttctacttc tcttattata aaaaaatatt ggtatggttt tattgtttgt tccatgattt
      781 taaagtcctt tcttctaacc aaagtgcata ctttgtagaa aaaagtgatc ttctgcaaag
      841 tatgtgttac ctgaagatcc tggactcttt taaataagat acgttttgca tcttatcatc
      901 acccccttta atgcttatta ttctatgtac atgattcatt cgataaataa aagtaaaccg
      961 tatcttgaac agatagtcaa ctgcaaacag aaaaaaggac tgtga
//
LOCUS       DARPZF010000167         1002 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.177, whole genome shotgun sequence.
ACCESSION   DARPZF010000167 DARPZF010000000
VERSION     DARPZF010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.177"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            52..307
                     /locus_tag="SLE65_002932"
                     /pseudo
     CDS             52..307
                     /locus_tag="SLE65_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752209.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            371..1002
                     /locus_tag="SLE65_002933"
                     /pseudo
     CDS             371..1002
                     /locus_tag="SLE65_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          344 a          181 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaaaa
      301 tataggctct ataatttatg ggactgatga atcaaaattg attcttcagt cccattgtta
      361 ttttaggtat atgattcgta cattgaaaga gttgaaaaac tatcttccga agccgtcaaa
      421 aaggaccctg ccaaaagtat tgatggtgga tgaatttcgt tcgcacgctt caattgtgga
      481 taaaatgagc tttatttgtg cggatggcga gactggaaaa ctcattgata ttttgcctac
      541 acgaaaattg tctcgattaa cacactattt tagtcgctgt gcaaatcctg aagcggtgga
      601 atatttagtg acagatatga acgccgccta cttccaactg acaaaacgtg tcttaccaaa
      661 tgcgaaagtc gtcattgatt gttttcatat catcaaacat ttgaatcagg cgttcaatga
      721 ttttcgtgta caagaaatga aaagattaca ccagttaggg caacgacggg aagccgagaa
      781 agtgaaaaag aactggcgct ttcttctaaa aaaccgtcaa aaaatcaatc actatgatta
      841 caaaacatgg cgcagttttc gtgcacctaa atacccgcta ctcactgaag caatgatgat
      901 tgatcgattg ctggcatttt caacgccttt aaaggacgcc tatacttttt tccatgagct
      961 gaccgaagcc tttagagaca aggaatcaga cttatttttt ac
//
LOCUS       DARPZF010000168          992 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.178, whole genome shotgun sequence.
ACCESSION   DARPZF010000168 DARPZF010000000
VERSION     DARPZF010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.178"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(21..94)
                     /locus_tag="SLE65_002934"
     tRNA            complement(21..94)
                     /locus_tag="SLE65_002934"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58..60),aa:Ile,seq:cat)
     gene            complement(108..181)
                     /locus_tag="SLE65_002935"
     tRNA            complement(108..181)
                     /locus_tag="SLE65_002935"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(145..147),aa:Met,seq:cat)
     gene            complement(209..281)
                     /locus_tag="SLE65_002936"
     tRNA            complement(209..281)
                     /locus_tag="SLE65_002936"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:Ala,seq:tgc)
     gene            complement(301..374)
                     /locus_tag="SLE65_002937"
     tRNA            complement(301..374)
                     /locus_tag="SLE65_002937"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(338..340),aa:Pro,seq:tgg)
     gene            complement(384..457)
                     /locus_tag="SLE65_002938"
     tRNA            complement(384..457)
                     /locus_tag="SLE65_002938"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(421..423),aa:Arg,seq:acg)
     gene            complement(468..553)
                     /locus_tag="SLE65_002939"
     tRNA            complement(468..553)
                     /locus_tag="SLE65_002939"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(517..519),aa:Leu,seq:taa)
     gene            complement(570..641)
                     /locus_tag="SLE65_002940"
     tRNA            complement(570..641)
                     /locus_tag="SLE65_002940"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(607..609),aa:Gly,seq:gcc)
     gene            complement(653..725)
                     /locus_tag="SLE65_002941"
     tRNA            complement(653..725)
                     /locus_tag="SLE65_002941"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(690..692),aa:Thr,seq:tgt)
     gene            complement(743..824)
                     /locus_tag="SLE65_002942"
     tRNA            complement(743..824)
                     /locus_tag="SLE65_002942"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(788..790),aa:Leu,seq:tag)
     gene            complement(832..904)
                     /locus_tag="SLE65_002943"
     tRNA            complement(832..904)
                     /locus_tag="SLE65_002943"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(869..871),aa:Lys,seq:ttt)
     gene            complement(908..980)
                     /locus_tag="SLE65_002944"
     tRNA            complement(908..980)
                     /locus_tag="SLE65_002944"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(945..947),aa:Val,seq:tac)
BASE COUNT          261 a          283 c          235 g          213 t
ORIGIN      
        1 tgaaacttac aacgccacaa tggaccttgt aggactcgaa cctacgaccg gacggttatg
       61 agccgtctgc tctaaccaac tgagctaaag gtccaggctc ttaaaaatcg cggcggaggg
      121 gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc
      181 gaaaaagata ttcattattt aaatgaaatg gagcctagcg ggatcgaacc gctgacctcc
      241 tgcgtgcaaa gcaggcgctc tcccagctga gctaaggccc cgtgtttaaa tttataatta
      301 tcgggaagac aggattcgaa cctgcgaccc cttggtccca aaccaagtgc tctaccaagc
      361 tgagctactt cccgtttaat taacgcgccc aagaggagtc gaacccctaa ccttttgatc
      421 cgtagtcaaa cactctatcc agttgagcta tgggcgcata tttgaaatgc cgaggaccgg
      481 aatcgaaccg gtacggtgat cactcaccgc aggattttaa gtcctgtgcg tctgccagtt
      541 ccgccacccc ggcgcgattg ctttggcaaa gcggaaaacg gggttcgaac ccgcgacccc
      601 caccttggca aggtggtgct ctaccactga gctatttccg cgtgtttaaa gatgccggct
      661 aaaggacttg aaccctcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      721 ccggcatgta aaacttaaat tatgcgggtg aagggacttg aacccccacg ccgtaaggcg
      781 ctagatccta aatctagtgc gtctgccaat tccgccacac ccgcaaaaat atgagccgta
      841 cagggctcga acctgtgacc ctctgattaa aagtcagatg ctctaccaac tgagctaacg
      901 gctcatatgg aggttaacgg gatcgaaccg ctgaccctct gcttgtaagg cagatgctct
      961 cccagctgag ctaaacctcc atggataact ta
//
LOCUS       DARPZF010000169          950 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.179, whole genome shotgun sequence.
ACCESSION   DARPZF010000169 DARPZF010000000
VERSION     DARPZF010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..950
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.179"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..>950
                     /locus_tag="SLE65_002945"
     CDS             <1..>950
                     /locus_tag="SLE65_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEI8450149.1"
                     /translation="YYKFPSFLIQNSKYSKMKDSSKIAYMLFKNEFRRALHEKWIDDD
                     GLLYLEFTQADLMDKLNCYQGKVKTILNELETYNLISVVKGEFNPKTKKNEKNKYYLL
                     QPEISADDLFIQNSFDDDLSETIDKSTSSRNAEIARREETAKTLDNTGNAEIARREKT
                     AETLDNTGNAEIAQDYYINKSLDTKRHLKDTETDQLQNQVLLDNFVEIMKEDSINTFV
                     PEKVLSLIKTFSNTYEEAQQTVTTIHKAKHKAEELEKTVVVYEELESYGIDADKGLYM
                     TLLKAYQKQKTEKVNNLQNLIFVYVKNWFIEKAIAAKLAN"
BASE COUNT          393 a          151 c          156 g          250 t
ORIGIN      
        1 atattataaa tttcctagtt ttttaattca gaattctaaa tactctaaaa tgaaagacag
       61 ctcaaaaata gcctatatgc tttttaaaaa tgaatttcgt agagccttac atgaaaaatg
      121 gatcgacgat gatggtctat tatatttgga atttacacaa gcagacctaa tggacaaatt
      181 aaattgctac caaggcaaag taaaaaccat tttaaacgag ttagaaacat ataatttgat
      241 ttcagtcgta aaaggagaat ttaacccaaa aacgaaaaaa aatgaaaaaa ataaatacta
      301 tttacttcaa cctgaaataa gtgccgatga tctttttatt caaaattctt tcgatgacga
      361 tttaagcgaa actattgata aatcaacctc ttctcggaat gcggaaatcg cacgtcgaga
      421 ggaaactgct aaaacccttg ataacactgg aaatgcggaa atcgcacgtc gagaaaaaac
      481 agctgaaacc cttgataaca ctggaaatgc ggaaatcgca caagattatt atattaataa
      541 atctttagac actaaaagac acttaaaaga cactgaaaca gaccaattac aaaatcaagt
      601 tttgctagat aacttcgttg aaatcatgaa agaagacagc ataaacacat ttgtaccaga
      661 aaaggtatta agcttgataa aaacattttc taacacttac gaagaagccc aacaaaccgt
      721 caccacaata cacaaagcaa aacataaagc cgaggaactt gagaagacgg tagttgtgta
      781 tgaagaactt gaatcttacg gaattgatgc ggataaagga ttatatatga cgttgctgaa
      841 agcttatcaa aaacaaaaga ctgagaaagt aaataatttg cagaatttga tttttgtgta
      901 tgtaaaaaac tggtttattg aaaaagctat tgcggcaaag cttgcaaacg
//
LOCUS       DARPZF010000170          943 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.180, whole genome shotgun sequence.
ACCESSION   DARPZF010000170 DARPZF010000000
VERSION     DARPZF010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.180"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..>943
                     /locus_tag="SLE65_002946"
     rRNA            <1..>943
                     /locus_tag="SLE65_002946"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          293 a          187 c          274 g          189 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact agg
//
LOCUS       DARPZF010000171          884 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.181, whole genome shotgun sequence.
ACCESSION   DARPZF010000171 DARPZF010000000
VERSION     DARPZF010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..884
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.181"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
BASE COUNT          311 a          144 c          139 g          290 t
ORIGIN      
        1 aaatgttgat cgtcagcaag gagctaaaaa atacgaatat atttcttttg tagtaaaatc
       61 ggactggttt gcatatcatt ttcttcgtaa atatcaaaat catgttaact actatcaatt
      121 actaataaaa actaccactt taagcgttaa gaactgttaa gtttagttaa gtgaggatag
      181 ttcacaaaat ccattgttaa acttcacgaa agtggtaaaa ctcaaaatgc tttatatagg
      241 attacagcat cgctctttct tcgattgcgc gttgggtaaa aaatattatg aagtaaaaat
      301 tgacgatgac acgttcctta cggctcatca gatgaaacag ctacaaaaac gaaatgatca
      361 actcgaagaa aatttaattc taaaaaagcg attgccatat tcacgcctcg ctcgacgaac
      421 tattaaaggt caagatttac ctgaagatca tcctttttag gaaattgaag ctttttatgt
      481 tgcacaatgc atttataata ctacaatgat gttttcacca gatattcttc tagggtgcgg
      541 tgtaatgaaa cagatacact tgcaaaagaa aattcaccgc gaatttacta aaattatgaa
      601 taattatgtt aatcttccga aatttttttc caaaattaag ggatcaagct ggtgttatag
      661 attgtttaag gttggcaaaa aaataacttc tttttaaaca attatagaaa accgatactc
      721 tgttaagttg gttgacacgg tgtcgatttt tatgactttc ttattctgaa acttcactaa
      781 cggacagtac ctaaaaagtc tatagtatgg acgtttacga gtactatttt atcaaaaatg
      841 ctgctcattt caacttatat gttttagtga actaccccca ctta
//
LOCUS       DARPZF010000172          852 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.182, whole genome shotgun sequence.
ACCESSION   DARPZF010000172 DARPZF010000000
VERSION     DARPZF010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..852
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.182"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(1..152)
                     /locus_tag="SLE65_002947"
                     /pseudo
     CDS             complement(1..152)
                     /locus_tag="SLE65_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(429..626)
                     /locus_tag="SLE65_002948"
     CDS             complement(429..626)
                     /locus_tag="SLE65_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEI8450150.1"
                     /translation="MNNGTVKWFNSDKGFGFITGEDGNDVFAHFSAIQGEGFKSLDEG
                     QAVTYDIEEGQRGPQAVNIVK"
BASE COUNT          284 a          159 c          116 g          293 t
ORIGIN      
        1 gtgatgacgg cacttttatg gtggatgccg acaatcgtat caccctctaa atgtccaaat
       61 tcttcttcga aaacgacata atctttttta cgctcagaaa tatttctttt gaatgcctgt
      121 tttccacgtt tttccttata accatttcat tgtgatccac ctcttttgtt tattagttta
      181 aaccatcaaa ccatttttaa taaaatatgt aaattccttt gctcaaaaaa gtagcttctt
      241 tacgattcga caatttcaaa taaagcaggt aaaaactggc tgtcagaaaa tagccaaact
      301 gaagcaaaaa ataatgttaa aattaattaa tgaacgaaaa aaatccctca cctaatatta
      361 cggtgaggaa ttttttctac cgacataaac aaaaaaacca cctcatatga ggcggttaac
      421 gttcaacatt attttacgat atttactgct tgaggaccac gttgtccttc ttcaatatca
      481 taagtaactg cttggccttc atctaaagac ttaaagcctt ctccttggat tgctgagaaa
      541 tgagcgaata cgtcatttcc atcttcacca gtgatgaaac caaaaccttt atctgagtta
      601 aaccatttta ctgtaccgtt attcatatat atttcctcct gatacgtata taatacgtgt
      661 tttattgcaa ttaatattac ttggtaaaag gagtttttat agtgtgaata tatcgctcag
      721 attacgtttc aaattagatt acttatttac tataacacgg atgtaatgct aacacaagga
      781 taatcactcg atatacggtt taaatattat tatttgtcaa attaagcgag acaaaacttt
      841 ccatttacgt aa
//
LOCUS       DARPZF010000173          791 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.183, whole genome shotgun sequence.
ACCESSION   DARPZF010000173 DARPZF010000000
VERSION     DARPZF010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.183"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..782
                     /locus_tag="SLE65_002949"
     CDS             <1..782
                     /locus_tag="SLE65_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEI8450151.1"
                     /translation="DMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNG
                     VSLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGE
                     LISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKL
                     IKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNIDKKVSSHMLRHSHISLLTELGI
                     PLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT          340 a          107 c          102 g          242 t
ORIGIN      
        1 aagatatgct agattactac tattttgaaa aaaatttatc atataattat gtaatacatt
       61 taaaaacttt tacaggaatg atttttaaat tcgccaaccg tcgatatgga ttaaaatata
      121 atcccgtaaa tggggtttct ttagcaagaa aacctaagac aaacgaagaa ataaaaaaag
      181 aaaaagatgg ttatttatca aaagaagaag ttcaaatgat tgctagtaaa caaaaaagtt
      241 cacatcaaca gtcacgttat tctttaatta ctaaattttt gtttttaact ggactacgtt
      301 atggtgaatt gatatctttg actgaatctg attatgatgg taataaaatt acggtttctg
      361 gtacttatga ttacgagtta aaaattaaaa caacaactaa aaatacaggt tcttatagaa
      421 ccattgaatt atcaagtaat gctaaagaaa tcatagatca attaattgaa gaaaacaaat
      481 taattaagaa taataaagat aaatacattt tcatctctaa aaatggtaac ccgatatcta
      541 ttcaagcata taatcaatct ttaagagcag tatccaaaga attaaacata gataaaaaag
      601 tttcttctca catgttaagg cattcccaca tttctctact tacagaatta ggaatcccat
      661 taaaagccat tatggatcgt gtaggacatg aagattcaaa aacaacatta aagatttata
      721 ctcatacaac taaaaatatg caaaatcaac tagtagaaaa actaggaaaa atagaaattt
      781 aaattgcccc t
//
LOCUS       DARPZF010000174          775 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.184, whole genome shotgun sequence.
ACCESSION   DARPZF010000174 DARPZF010000000
VERSION     DARPZF010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..775
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.184"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(249..728)
                     /locus_tag="SLE65_002950"
     CDS             complement(249..728)
                     /locus_tag="SLE65_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450152.1"
                     /translation="MCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNSL
                     DFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKGKKIKKCDKCFESAVVKFPQFKLNP
                     AASIQFQGHVFDVLAKDNIKKYKKGNIFHIDIQISSNLEDIKKAFKIKTIGTAPNFK"
BASE COUNT          262 a          106 c           87 g          320 t
ORIGIN      
        1 tgacgctccc ttaacaataa atgaagactt ttttattgtt aattgtttat ttttctatta
       61 ttagatatga aaatcgcatt tagataaaat agaaaaatat gaatatattt taaatattaa
      121 gatgagagtc attaacttat gatagtagtc aatttgcttt tcactaatta caaaatatgt
      181 gatataggaa gtttagttat tgttctcata atgccatcct gtttttagat tatctagtaa
      241 tttttttgtt atttaaaatt aggagcagtg ccaattgttt taattttaaa ggcttttttt
      301 atatcttcta aattagaaga tatttgtata tcaatatgga atatattacc ttttttgtat
      361 ttttttatgt tatctttagc taaaacatca aatacatgtc cttgaaattg tatcgaggca
      421 gctggattta gtttaaattg aggaaacttt accacagctg attcaaaaca cttgtcacat
      481 ttttttattt ttttaccttt gtaaaaatat tcgattgaat attctatttg gcacgactca
      541 cttggcagta tatgtatgtc aatatttttc atctgtttca taggtatttc aaaatctaaa
      601 ctattaaaaa catataattc cctgtaatta tttacatcta actctactaa atttatcttt
      661 ggaacaatag atcctccacc cattccacca taataaaaaa aatcttgttc tctatcaaaa
      721 tagcacatat taagctcagt ttgtttatca tcctcaataa ttttataaat caaac
//
LOCUS       DARPZF010000175          765 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.185, whole genome shotgun sequence.
ACCESSION   DARPZF010000175 DARPZF010000000
VERSION     DARPZF010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.185"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            660..>765
                     /locus_tag="SLE65_002951"
     rRNA            660..>765
                     /locus_tag="SLE65_002951"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          315 a          124 c          134 g          192 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactctc gatgaagtag acctttgaaa actgaacaaa
      541 gtaagacaaa ccaaatgtgt agggcgtctt gattcaattc aagacaacaa acatttttaa
      601 caagcaagca atatgctagc aaacaaattg agcttaacaa tcgcaagatt gttcgaactt
      661 tttatgagag tttgatcctg gctcaggacg aacgctggcg gcgtgcctaa tacatgcaag
      721 tcgaacgctt ctttttccac cggagcttgc tccaccggaa aaaga
//
LOCUS       DARPZF010000176          735 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.186, whole genome shotgun sequence.
ACCESSION   DARPZF010000176 DARPZF010000000
VERSION     DARPZF010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.186"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            220..>735
                     /locus_tag="SLE65_002952"
     CDS             220..>735
                     /locus_tag="SLE65_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HEI8450153.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIE"
BASE COUNT          255 a          114 c          163 g          203 t
ORIGIN      
        1 ttttctgaag tacatccgca actgtccata ctctgatgtt ttatatcttt tctaaaagtt
       61 cgctagatag agttctatat tagagatgta aagagttttg gtgaagaggt ttgtgagtat
      121 ggcttttata accagggtgc aatgagaagc actaacagca gctagcttaa gaacgcatag
      181 gatatacttt ttatggaagt cacagaggag gaataaaatt tgaacaggat taacagagta
      241 acctctattc ttattcagct gcaatcaaaa aaaataattc ctgccaaaga aattgcacag
      301 cgatttaata taagcttaag gacagtttac agagatatcc ggacacttga agaagccgga
      361 ataccaattg gatctgaggc cggaaaagga tattttcttg tagagggctt cctacttccg
      421 ccggtaatgt ttacagcggc ggaagtgggt gcattgatta cagcagggaa atttttaaat
      481 tgccatggag atgaatcatt tataaaggat tttgattcag ctatgtataa aatcaaatct
      541 attttgaagc atggtgaaaa aaactatgca caggagttgg agaacagtat taacgtgtac
      601 agcacatctg gacagaaaaa tacattggcg gataacgtta ttgcagcaat tcagactgca
      661 atctgcaata aaagggtaat atcaattcaa tatcctgcat caggagggca agaaccggaa
      721 agcagaatga tagag
//
LOCUS       DARPZF010000177          720 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.187, whole genome shotgun sequence.
ACCESSION   DARPZF010000177 DARPZF010000000
VERSION     DARPZF010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.187"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            82..>720
                     /locus_tag="SLE65_002953"
     CDS             82..>720
                     /locus_tag="SLE65_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HEI8450154.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGC"
BASE COUNT          237 a          127 c          141 g          215 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcgaa cccattggac ggctcaaagt tattttgttc aacccagaca ttcaatcgcg
      421 aatcatgtca gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaaatt gtcaggtatc tttgaccacc gttattcgta cgttgaaaga gtttaaaagc
      541 tacttaccaa agcaatctaa gaggattctc cccagagtat tgatggttga tgaatttcgt
      601 tcgcacgctt ccatagaaga taaaatgagc tttatttgcg cagatggcga aacaggacaa
      661 ttaattgatg tcttgcctac gcgtaaattg cctcgattaa caagctattt cttaggctgc
//
LOCUS       DARPZF010000178          697 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.188, whole genome shotgun sequence.
ACCESSION   DARPZF010000178 DARPZF010000000
VERSION     DARPZF010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..697
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.188"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..580
                     /locus_tag="SLE65_002954"
     CDS             <1..580
                     /locus_tag="SLE65_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEI8450155.1"
                     /translation="EKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIK
                     ELDKAIEQVIVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWK
                     VNQSGNYQSQNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKR
                     ALVLTARKFTRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          258 a          133 c          120 g          186 t
ORIGIN      
        1 agaaaaaatc gctaaagcaa ttcaacgtgc aattaccatg agttaccgcc taggtgctct
       61 tgcacaagaa tcaattaatg ttgttttaag tgttctcgta cgagaaatac gagcacttga
      121 aaaaaatatc aaagaattag ataaagccat cgaacaagta attgttgtca ttccagaata
      181 tcaatgctta accagtattc caggcgttgg taaagtctat gctgccggtt taatcgctga
      241 aattggtcaa atcgaaagat ttgaagatca gacaaaattg gcaaaatacg ctggattaag
      301 ttggaaagtg aaccaatctg gaaactatca gtcgcaaaat acacctctga caaaacaagg
      361 aaatcgatat tttagatact acttagttga agctgccaac tctgtaaaaa attatcttcc
      421 tgaatacaaa gctttttatc aaagtaaata taaggaggtt ccaaagcatc aacacaaacg
      481 tgcactcgtc ctaaccgcaa gaaaatttac gcgtctggtg gatacgctac tacgtaaaca
      541 ccaactctat acgccaccaa ggagtgtgat agagaaataa caatccgtta ttgacgcaaa
      601 tccttgaatc aacccgaaaa aaatttgatt ttgatcgggt ctagtttcgt gcgcttcaaa
      661 acatattact caataaagaa aatcttaaat ttcatct
//
LOCUS       DARPZF010000179          694 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.189, whole genome shotgun sequence.
ACCESSION   DARPZF010000179 DARPZF010000000
VERSION     DARPZF010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.189"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
BASE COUNT          247 a          116 c           84 g          247 t
ORIGIN      
        1 ccaaattact tcatcaaaac attgatataa tttttattat atcagtattt attcttgata
       61 cataaatgag aaaataaata ctttaaatct attgactaca agtagtcatt aagtcttcat
      121 aagatgtaca atatgacatt aaaaaaataa aagcttacga ccatccgtta aatctgacac
      181 taaataatgg actgctttct tttgtattag caggttacgt tgactatgaa tattcaccag
      241 attatttgga gaaacctctt caacacgaga acaatgatat taattttaga tttgtctacg
      301 agtcaaaaag taaaacatgg ttagttgatc aattaagcac gataaacaca agcttccatg
      361 aattacctaa acctgaaaat gaagttgaga tggtcattaa aatcttctaa aaaagaagcg
      421 ttgaagggga aatattcctt tcaacgctct tttttatatg cttagaaaca taaataaatt
      481 gtatactttc tttttagccc ctattacttt tcacgaaaaa tatctttttt tcgacgctag
      541 cgtttctcta cttctaatac tgtacacagt ttttgtatta ttgaaaaatt actcattatt
      601 tagcattaat ccacatcgtt ttatcaatcg accttcatac taaactactt taaagtcatc
      661 ttccttctcg tttttcatta atggaatggc aaca
//
LOCUS       DARPZF010000180          677 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.190, whole genome shotgun sequence.
ACCESSION   DARPZF010000180 DARPZF010000000
VERSION     DARPZF010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.190"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..>677)
                     /locus_tag="SLE65_002955"
     rRNA            complement(<1..>677)
                     /locus_tag="SLE65_002955"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          138 a          219 c          146 g          174 t
ORIGIN      
        1 tgcttaatgc gttagctgca gcactgaagg gcggaaaccc tccaacactt agcactcatc
       61 gtttacggcg tggactacca gggtatctaa tcctgtttgc tccccacgct ttcgagcctc
      121 agcgtcagtt acagaccaga gagccgcctt cgccactggt gttcctccat atatctacgc
      181 atttcaccgc tacacatgga attccactct cctcttctgc actcaagtct cccagtttcc
      241 aatgaccctc cccggttgag ccgggggctt tcacatcaga cttaagaaac cgcctgcgct
      301 cgctttacgc ccaataaatc cggacaacgc ttgccaccta cgtattaccg cggctgctgg
      361 cacgtagtta gccgtggctt tctggttaga taccgtcaag ggatgaacag ttactctcat
      421 ccttgttctt ctctaacaac agagttttac gatccgaaaa ccttcttcac tcacgcggcg
      481 ttgctcggtc agactttcgt ccattgccga agattcccta ctgctgcctc ccgtaggagt
      541 ttgggccgtg tctcagtccc aatgtggccg atcaccctct caggtcggct atgcatcgtg
      601 gccttggtga gccgttacct caccaactag ctaatgcacc gcgggtccat ccatcagcga
      661 cacccgaaag cgccttt
//
LOCUS       DARPZF010000181          650 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.191, whole genome shotgun sequence.
ACCESSION   DARPZF010000181 DARPZF010000000
VERSION     DARPZF010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.191"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..>650
                     /locus_tag="SLE65_002956"
     CDS             <1..>650
                     /locus_tag="SLE65_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEI8450156.1"
                     /translation="KSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSA
                     RTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSIT
                     FDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSV"
BASE COUNT          213 a          112 c          134 g          191 t
ORIGIN      
        1 caaatcaaac tgtggtagac gtccgcttgt tttacccgag gaacaatcag aatatattca
       61 aagaaaggtt gttcaaggat ggacacccga tgtgattgtt ggtcgtgcag cgtttcctat
      121 tagttgttct gctcgtacca tttatcgtat gttcaaaaag gggctatttg attcttctga
      181 cttaccgatg aaaggcaagc gtaaaccgaa tggacatcaa gaaagacgtg gaaaacaaac
      241 tttccgccgc tctattcatg aacgtgaaaa ggattatagc caattctcaa atgagtttgg
      301 tcaccttgaa ggtgacacta tcgtaggtct gaaacataaa agtgctgtaa ttaccttagt
      361 tgaacgatta tcaaaagtta tcatcacatt gaaaccgtgt ggtagacaag cgattgatat
      421 tgaaaaaaaa ttaaatcaat ggtttgaatc tgtaccgaaa aacctattca aatccatcac
      481 ttttgattgt ggaaaggaat tttcaaattg gaaacagatc agtaatgtca atgatattgc
      541 catttatttc gctgatccag gaacgccgtc tcaaagaggc ctaaacgaga attctaacgg
      601 attgttacgt agagatggtt tattgaaatc tatggatttc aattcagtag
//
LOCUS       DARPZF010000182          632 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.192, whole genome shotgun sequence.
ACCESSION   DARPZF010000182 DARPZF010000000
VERSION     DARPZF010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..632
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.192"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..>632
                     /locus_tag="SLE65_002957"
     CDS             <1..>632
                     /locus_tag="SLE65_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HEI8450157.1"
                     /translation="LSSNLAYTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQ
                     AKLLNQIAKVGYNSTKKSYFYGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEA
                     NLPNILGDKGYISHKIHEKLALKGITISVPPRKNMDKSEKLDHSLLGKQRKTVETVFS
                     SLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT          224 a          112 c          109 g          187 t
ORIGIN      
        1 gcttaagttc aaacttagct tacactatca agattattcg atactttttc atcaagaagc
       61 tcaccaaagg tgaactagtc ggaattatag atagttttcc tagtccatta tgtaaaccag
      121 ttagaaatag acaagcaaaa ctattgaatc aaatagccaa agttggctat aactcaacaa
      181 aaaaatctta tttttatggt cttaaaattc atatgatcgt tactaagact ggctttccga
      241 ttacttactc aatcacgaat ccaggtgtcc atgacgtgaa agtgttagag actttatcgg
      301 aagaagcgaa tcttcccaat atcctagggg acaaaggata tattagccat aaaatccatg
      361 aaaagcttgc ccttaagggc attactatat ccgttccgcc acgtaaaaac atggataaat
      421 cagaaaaact agaccacagc ttacttggaa aacaaagaaa aacagttgag actgtttttt
      481 cttccttaga aaaattaggt tgtcaaaatt tcaactcacg ttctgttaaa gggctagaga
      541 gtagatttga aagcatatta ctggcttaca gtgttctatt aagtcgagca caacgacgtt
      601 ttgaaggaac tttgagatat tctttaggat at
//
LOCUS       DARPZF010000183          611 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.193, whole genome shotgun sequence.
ACCESSION   DARPZF010000183 DARPZF010000000
VERSION     DARPZF010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.193"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..>611
                     /locus_tag="SLE65_002958"
     CDS             <1..>611
                     /locus_tag="SLE65_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEI8450158.1"
                     /translation="DAKWPEEATQPITADDTEFVSSATKLDDIIENPGENIPAGYHKV
                     TFTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEATQPITADDTE
                     FVSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDTKYTWKEKVDV
                     SAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          248 a          100 c          138 g          125 t
ORIGIN      
        1 gatgcgaaat ggccagaaga agcaactcaa ccaattacag cagatgatac agaatttgta
       61 tcaagtgcaa caaaactgga tgatatcatt gaaaatccag gagaaaacat tcctgcaggc
      121 taccacaaag taaccttcac cgcaggagaa ggaacaagta ttgaaagtgg aacaacagtc
      181 tttgcagtga aagacggcgt aagcttacca gaagataaac ttccagtgtt gaaagcaaaa
      241 gatggttata cagatgcgaa atggccagag gaagcaactc aaccaattac agcagatgat
      301 acagaatttg tatcaagtgc aacaaaactg gatgataaat ctgacgctga caaatataat
      361 cctgaaggtc aaaaagtgac tacagaattg aataaggaac cagacgcatt tgagggaatt
      421 aagaacaaag aagatttacc aaaagatact aagtatactt ggaaagaaaa agtagatgtt
      481 agcgcagctg gaaataaaaa agggactgtt gtagtgacat atccagatgg atcatctgat
      541 gaagttgaag tagatgttac agtgacagac aatcgttctg acgccgataa atatgagcca
      601 acagtagaag g
//
LOCUS       DARPZF010000184          605 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.194, whole genome shotgun sequence.
ACCESSION   DARPZF010000184 DARPZF010000000
VERSION     DARPZF010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.194"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..220)
                     /locus_tag="SLE65_002959"
     CDS             complement(<1..220)
                     /locus_tag="SLE65_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEI8450159.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGN"
     gene            complement(217..510)
                     /locus_tag="SLE65_002960"
     CDS             complement(217..510)
                     /locus_tag="SLE65_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450160.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
BASE COUNT          173 a          132 c           88 g          212 t
ORIGIN      
        1 tgtttcctcc ttcttcgctt tcagccgaga acattttgta ggttcgattt gatacaccca
       61 acacactccc taaaaacgcg ccaaaaccag taatgatgac aacacagata tctgtgtact
      121 gccaattgag cgctttacca actaacccca cgaaagtagc tagtgcggga ataattacca
      181 gtgcgaacca ttttagtact tcgaacgttt tattattcat tttcttctct ccctaaacaa
      241 agttttgatt tgttgcgtgt gttccaccaa tttttctgta tgtgtatcta atctttcatc
      301 gtgtttcttt agttcttcat gaatcatcaa tcgatctgat ttgctcgatt ctaaatcttt
      361 agtcagcaaa tctaaattgt ggcttacttt tgaaagagtc tcagtaattt tcgagaaaga
      421 tgcagcaatc ggtctaatta ctaataaaat caaagaaacg atagcggtta ttgatcctgc
      481 tatcattccc cattccccta aattaatcat gtgacaactc ctttacctta aataaaaacg
      541 catcaattaa gatgcgctct tatctttatt aatgatttta tctgcttctt cgtctgtaat
      601 gcata
//
LOCUS       DARPZF010000185          599 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.196, whole genome shotgun sequence.
ACCESSION   DARPZF010000185 DARPZF010000000
VERSION     DARPZF010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.196"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(310..>599)
                     /locus_tag="SLE65_002961"
     CDS             complement(310..>599)
                     /locus_tag="SLE65_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450161.1"
                     /translation="ETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINLYYSNK
                     NYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
BASE COUNT          207 a           98 c           90 g          204 t
ORIGIN      
        1 attgtgagat gataataaag aagagtttaa agcgcacccc aagccacttc cccataagtg
       61 tgttacgctt taaactcttt tatatttgaa gctattaaaa ggcataccat atttttgaaa
      121 aaaagtgaga aaaaaggctt acaattggag tggtagttaa ttagtgactt atttttgatt
      181 ttatagcact gatactataa aatatagata tcatcatatt acacaatctt aatactaact
      241 taaaaaatat ctcctttcac aagtatggtg ataaaattcg ttccgggcta cctttttagg
      301 tagcctactt taatctttgt atctttctgg atcaacgaaa gtatacttta tatagtcata
      361 acgccgatga tcgctacgtg cgtccggcac gtcagtcacg atatcaaaca aaaagtatac
      421 atccttcttc attctagttt tcgcagcagg aattttgaaa tagttcttat tagaatagta
      481 gagattgatt aataagctat cttcgattgc taaaaagaaa acttctgaat tccatacttt
      541 ataaaaatct ttgataaatc tattcgaagg gtcaaattta aaccataatt gtgtctcat
//
LOCUS       DARPZF010000186          591 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.197, whole genome shotgun sequence.
ACCESSION   DARPZF010000186 DARPZF010000000
VERSION     DARPZF010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.197"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(316..579)
                     /locus_tag="SLE65_002962"
     CDS             complement(316..579)
                     /locus_tag="SLE65_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEI8450162.1"
                     /translation="MKKNLLLVLPILGFAGFFVGVPMLSANIGISSYAAKKVIDIINT
                     GSTVATIISIVAAVVGGGLITAGIVATAKSLIKKYGAKYAAAW"
BASE COUNT          224 a          103 c           78 g          186 t
ORIGIN      
        1 cttccttttt tgtatggatt ttttcattta cacaaaatat tttatactct cctgaatttt
       61 ttcatgttga aaacatcact aatcaaaggc aaattataat ttagaaatag aatgaaaaca
      121 ctaaatgaaa atagaacatt agaaaaaata gaatcaaaaa aacccaagac tagtgccgaa
      181 ataagggaaa caatcgaagc tacaaaaaat aatgatttcg ttgaacagga ccaatttatt
      241 tgtttccgat atttctcaaa aagaactttc tttgggaaag ttaaaggcga ctgtaaagtc
      301 gcctttagtc cttttttacc aagctgctgc atatttagct ccatattttt taattaatga
      361 tttggctgta gcaacaatac cagctgtaat taatccgcct ccaacaactg cagcaacaat
      421 agaaatgatt gtagcaaccg tgctaccagt attaattatg tcaataactt ttttagctgc
      481 ataagaagaa attccaatgt tagcacttag cattggtaca ccaacaaaga atcccgcaaa
      541 acctaaaatt ggtaaaacta ataataaatt ctttttcata ataattcctc t
//
LOCUS       DARPZF010000187          577 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.198, whole genome shotgun sequence.
ACCESSION   DARPZF010000187 DARPZF010000000
VERSION     DARPZF010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.198"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(138..491)
                     /gene="tnpB"
                     /locus_tag="SLE65_002963"
     CDS             complement(138..491)
                     /gene="tnpB"
                     /locus_tag="SLE65_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEI8450163.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
BASE COUNT          183 a          123 c           93 g          178 t
ORIGIN      
        1 ttgaagcaac tgaagcaacg tatctgtagt ttccaaaatt tttcaccacc ttgaatcgaa
       61 ctgattttgt tacagaatac cacaagaaac gcacaagaaa taggggttca acacattttt
      121 tgtgttaacc ccccagctta aaaaactcct ttttttcctg gcaaaatagc tcgaggttga
      181 tcgatactta atccttctaa caaccatcga acctgttggt tcgttaaggt tcgaacttcg
      241 tctttcgtcc gaggccattt taacttgccg ttttctatcc gcttataaca gagaagaaaa
      301 ccatcaccgt cccaatagag aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa
      361 acggcatctt cgtaaagctc gagttgatac tcttgttgaa taagactggc aagaccatca
      421 attccttttc gcaaatctgt ttttccgcac acaatataaa tatgtttggt ttgaagtaaa
      481 tcataaagca ttggacaaca gttctttcaa aatagcttga agaatataat tgttaatacc
      541 gttatagatc aaaacttcag aaccattctc tcttttg
//
LOCUS       DARPZF010000188          575 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.199, whole genome shotgun sequence.
ACCESSION   DARPZF010000188 DARPZF010000000
VERSION     DARPZF010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.199"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            312..>575
                     /locus_tag="SLE65_002964"
     CDS             312..>575
                     /locus_tag="SLE65_002964"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HEI8450164.1"
                     /translation="MSAVVTDLTYVRVGTNWAYICLMIDLFNREIIGHSCGNKKDAQL
                     VKRAIQSIPYSLQEIELFHTDRGKEFDNQTIQNLMNGLVIKFLS"
BASE COUNT          195 a          105 c           82 g          193 t
ORIGIN      
        1 ttttacactc tctattattc ttttcataaa tattgtaaat agaagtatta aaaatatata
       61 caaaaagtat tatttcgaga aagataaata ttttcaaaaa ccttttcata atcctcaccc
      121 tttcttacac tgataaatca tgcgtctaat attcaaatta tactcgatat gctttagcta
      181 atcagccaac tctgtttgtc tactatcatt atatcaatag acaatatctg ctcccgtctt
      241 tatgatcgtg ccaaagcaat caaaagaaaa ttgcgaatca cttagatcga aagtttactc
      301 aaacaaaagc attgtcagcg gttgtcacgg atttaactta tgttcgggtc gggacaaatt
      361 gggcttatat ttgtttgatg attgatttat tcaatcgtga aattattggc cattcttgcg
      421 gaaataaaaa agatgcgcag cttgtaaaaa gggccattca aagcattcct tactcacttc
      481 aagaaatcga actcttccat acggatcgtg gaaaagaatt tgataaccaa accattcaga
      541 atctcatgaa tggtttggtt atcaaattcc tttcc
//
LOCUS       DARPZF010000189          543 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.200, whole genome shotgun sequence.
ACCESSION   DARPZF010000189 DARPZF010000000
VERSION     DARPZF010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..543
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.200"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            180..416
                     /locus_tag="SLE65_002965"
                     /pseudo
     CDS             180..416
                     /locus_tag="SLE65_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          183 a           93 c           88 g          179 t
ORIGIN      
        1 ttcgcaacga tagcaaccgg agtttcttga tgaaaatatg cttctatcat tacaagctcg
       61 tttggtgtaa gatgggtata agtcatttat gttcactctc cttgtatgct ttagcgggta
      121 ttacaattgg agtgtaacat aaatggcttt tttatttgtc tcgcttaatt atacaaacgg
      181 cgttattaaa aaatcttcct gaaacacttg atgcacaact tcgcacgaaa cttcaaaacc
      241 ttttaacgta tgaagaaggt atttacaatg ctatgattta cccgtattct aatggcaaaa
      301 tagaggccaa gattccccat atcaagacac tgaaacgatt atcttatgga tttaaatcat
      361 ttgagaacat gaaaatcagg atttttttga tcaatcaatt gattcaagtg aaataacaaa
      421 aaaatctgag acagaaggtc agtccttcta tcggctctat actttttgat gttggtgaac
      481 ttcaccaaca tcttttttgt ataaaaaaat atagaaaaga caccctgaaa tcctttagaa
      541 tta
//
LOCUS       DARPZF010000190          534 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.201, whole genome shotgun sequence.
ACCESSION   DARPZF010000190 DARPZF010000000
VERSION     DARPZF010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.201"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            17..>534
                     /locus_tag="SLE65_002966"
     CDS             17..>534
                     /locus_tag="SLE65_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HEI8450165.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDATYIPLKRQT"
BASE COUNT          196 a          100 c           86 g          152 t
ORIGIN      
        1 aaaagaggac ttccctatga atgattttac tacagaaatt gtgcaaactc tagtcactaa
       61 aggcgattta aatgaattat tccgttcgca cttagaaaaa gcgataaaca cactcctacg
      121 gactgaatta acggcttttt tagattacga aaaatatgat cgcactggtt ttaattcagg
      181 taattcgaga aacggttctt actttcgatc aatcaaaacc gaatatggtg aattaacatt
      241 ggaaatacct agagatcgta atggtgagtt taaacaacaa actttaccag cctacaaaag
      301 aacaaacgat acattggaaa ccactattat ccatttattc gaaaaaggtg ttacgatgtc
      361 tgaaattgct gatttgatcg aaaaaatgta cggtcatcac tatactccac aaaccatgtc
      421 caacatgact aaagttctga ctgaagaagt aaatgccttt aaatccagag ccttaaatga
      481 taagtatgtc gctattttta tggacgctac ttacattcca ctaaaacgtc aaac
//
LOCUS       DARPZF010000191          528 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.203, whole genome shotgun sequence.
ACCESSION   DARPZF010000191 DARPZF010000000
VERSION     DARPZF010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.203"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..>528
                     /locus_tag="SLE65_002967"
     CDS             <1..>528
                     /locus_tag="SLE65_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HEI8450166.1"
                     /translation="IIKHMNQAFNELRIREMNELRKVGQKSQAEKLKKNWRFLLKNRA
                     NINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAYPYFHELVEAFRDKDPDL
                     FFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNGKIEAKNTHIKTMKRVSY
                     GFKSFENMRIRIFLI"
BASE COUNT          188 a          103 c           98 g          139 t
ORIGIN      
        1 atattatcaa acacatgaat caagccttta atgagttgcg tatccgtgaa atgaatgaac
       61 ttcgtaaagt aggacagaaa agtcaggcag aaaaactgaa aaagaactgg cgctttttgc
      121 taaaaaatcg tgcaaacatc aaccattatg aatacaaaac atggaaaagt tttcgagcac
      181 caaaataccc atttcttacg gaagcgatga tgattgatcg attgcttggc ttttctacgt
      241 ccctgaagga ggcgtatccc tattttcatg aattagttga agcctttcga gacaaagacc
      301 ctgacttatt tttctcctta ttggcagaac ttcccgaaac gttagatgac ggctttcggg
      361 aaaagctcca aaaccttctg acctatgaag aaggcatcac caacgcgatg atctatcctt
      421 acaccaatgg aaaaatagaa gcgaagaata cccatataaa gacaatgaaa cgagtatcct
      481 acggatttaa atcatttgag aacatgagaa ttagaatctt tttgatca
//
LOCUS       DARPZF010000192          511 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.204, whole genome shotgun sequence.
ACCESSION   DARPZF010000192 DARPZF010000000
VERSION     DARPZF010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.204"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..132)
                     /locus_tag="SLE65_002968"
     CDS             complement(<1..132)
                     /locus_tag="SLE65_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEI8450167.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          184 a           93 c           92 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag a
//
LOCUS       DARPZF010000193          488 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.205, whole genome shotgun sequence.
ACCESSION   DARPZF010000193 DARPZF010000000
VERSION     DARPZF010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.205"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..414)
                     /locus_tag="SLE65_002969"
     CDS             complement(<1..414)
                     /locus_tag="SLE65_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450168.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPFF"
BASE COUNT          185 a           78 c           62 g          163 t
ORIGIN      
        1 aaaaaacggc tttccaaatg atgaaatacc taaatctaac ttattaagaa agttgaaatt
       61 tttatattca ggaaaccatt tattaatttc atgtgcagca cgtaatgcat tccctggagt
      121 tgtcaaagag aaaattaatt ctgctaagct tattattgaa aatactgata acttataatt
      181 atatcgtcca ttgacaatca aatataaact aactatactt gttagaacaa aaaaacaggc
      241 gttgacttgt tcttgattag ttaaaaatat caataaagga atacttaccc aatatatttt
      301 tctatttatt tcttctcctc ttaagagttg aaaaaacgga taaaaagtta gtaaactaaa
      361 tgctactggc cactgatagt tcaaggtggt tgctctccaa ccggtttccc ccattactgt
      421 caatggtatt aaacagtata tagagcaaac caataataaa tttttaacat ttattttctc
      481 aaaaacat
//
LOCUS       DARPZF010000194          487 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.206, whole genome shotgun sequence.
ACCESSION   DARPZF010000194 DARPZF010000000
VERSION     DARPZF010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.206"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..>487)
                     /locus_tag="SLE65_002970"
     CDS             complement(<1..>487)
                     /locus_tag="SLE65_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HEI8450169.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IK"
BASE COUNT          142 a           92 c           86 g          167 t
ORIGIN      
        1 gttttatccg ttcattattg tagtaataga tatagctatc gatggctgat tttaattcct
       61 cgaaacagtt ataaactttc ccgtgaaaaa tctcttgttt taataagcca aaaaaattct
      121 ccataagtga attatctaag cagttccctt tccgagacat gctttgaaag attttgtact
      181 ccttcaattt gtttctataa gctttcattt gatacgccca accttgatct gagtgaaacg
      241 tacgacgata gggacaatcg ttagtggtct ggatagcttc ctccaaacct tccattaccg
      301 ctaatgcatt gggcttttca gagatacgat aggataaaat ctcactattg aacatatcca
      361 taaaaggatc tagatacaat ttcttttgac ggataatgcc tttggcatcc acttcatggt
      421 atttaaattc agttgtatcc gtcgtgattt tctgatggca gatactggtg tagaaacgac
      481 gatggat
//
LOCUS       DARPZF010000195          467 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.207, whole genome shotgun sequence.
ACCESSION   DARPZF010000195 DARPZF010000000
VERSION     DARPZF010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.207"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            1..467
                     /locus_tag="SLE65_002971"
                     /pseudo
     CDS             1..467
                     /locus_tag="SLE65_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          191 a           84 c           87 g          105 t
ORIGIN      
        1 tctaagagaa cacgaagaac tttttcacaa gaattcaagc aacaaatcgt caatctttac
       61 ttagctggaa agccacgtgt agaaatcatt cgagaatatg aactaacggc ttcagcattt
      121 gacaaatggg taaagcaatc taaaacgagt ggttcattca aagaaaaaga taatcttacg
      181 cctgaacaaa aagaattgtt agaactacgt aaaagaaacc agcaattaga aatggaaaat
      241 gatattttaa agcaagcagc gctgatattc ggacgaagag acaagtaatc gatgcgaata
      301 agcatcttta ccctatatca gcgatgtgca gaatattagg tctatcacgt cagtcctatt
      361 attatcaatc aaaaccaaag aaagacgaat cagaacttga agaagtagtc gctgaagaat
      421 ttatccgcag ccgaaaggcc tacggctcaa gaaaaataaa aaaagcc
//
LOCUS       DARPZF010000196          460 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.208, whole genome shotgun sequence.
ACCESSION   DARPZF010000196 DARPZF010000000
VERSION     DARPZF010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.208"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(20..91)
                     /locus_tag="SLE65_002972"
     tRNA            complement(20..91)
                     /locus_tag="SLE65_002972"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="SLE65_002973"
     tRNA            complement(113..200)
                     /locus_tag="SLE65_002973"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="SLE65_002974"
     tRNA            complement(225..298)
                     /locus_tag="SLE65_002974"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="SLE65_002975"
     tRNA            complement(312..382)
                     /locus_tag="SLE65_002975"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="SLE65_002976"
     tRNA            complement(384..459)
                     /locus_tag="SLE65_002976"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
BASE COUNT          132 a          128 c          108 g           92 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca
//
LOCUS       DARPZF010000197          454 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.209, whole genome shotgun sequence.
ACCESSION   DARPZF010000197 DARPZF010000000
VERSION     DARPZF010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.209"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(10..216)
                     /locus_tag="SLE65_002977"
     CDS             complement(10..216)
                     /locus_tag="SLE65_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEI8450170.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
     gene            complement(349..>454)
                     /locus_tag="SLE65_002978"
     CDS             complement(349..>454)
                     /locus_tag="SLE65_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEI8450171.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT          131 a          100 c           60 g          163 t
ORIGIN      
        1 tctatcctcc tatttatctg atgaaatttt cttatacgtt cgatttgata cacctaaaat
       61 actccctaga aatgctccaa aacctgtaat aatcatcacc gttatatctg tgtaccgcca
      121 gttaacacct tttccgacaa gaccgacaaa agtcgctaaa gcggggataa ctactatagc
      181 gatccatttc aaaatatcaa aggttctatt gttcatacta tccacctccc ttcattggtt
      241 gggctacttt ctttttcaat cgcttgtttt cttctatcaa tatttctctt tctgaaagca
      301 aggcatcaat ttgcccgtcc agttgttcaa ttttatcttt cttaattgtc aaattaagtt
      361 agacagatca tcaatactta cgtaactcaa aaatacttcc aaaggtgttc gataatccag
      421 tgattttcta ggaatattat ttcgtttaga tgcg
//
LOCUS       DARPZF010000198          453 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.denovo.210, whole genome shotgun sequence.
ACCESSION   DARPZF010000198 DARPZF010000000
VERSION     DARPZF010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..453
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.denovo.210"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..>453)
                     /locus_tag="SLE65_002979"
     CDS             complement(<1..>453)
                     /locus_tag="SLE65_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8450172.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAF"
BASE COUNT          136 a           81 c           93 g          143 t
ORIGIN      
        1 agaaagcttc taaaggaagc tcagcaagtt catccaatgt gaaatcttcc gtcatgagtg
       61 aaatgagggt tgcactaaaa agactcgtcg attcgtctcg catttctcga gcaagcgtat
      121 tacatttgta cgttagattt tcaagaaaat gttgctttgt acgaatcaat tgcttaataa
      181 gttgatagcg agtacgtgtt aaacgctgta aggccatgta tttctcttct ttgatagggg
      241 aagttgtgaa tcgttgaata cgcaagaaat cagcgattct taatgcatcg tttcgatcag
      301 ttttattctc atcaaacatg cgactaaatt gtttcacccg aaaaggattt tcaatcgtta
      361 caagtgtgtt gagcttcttt agtttctcat cttcatgaaa aaacatggaa ggatggaagc
      421 tgtacatgga cgttgactcc atgccaatca caa
//
LOCUS       DARPZF010000199        39546 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.guided.021, whole genome shotgun sequence.
ACCESSION   DARPZF010000199 DARPZF010000000
VERSION     DARPZF010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39546
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.guided.021"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            196..2385
                     /locus_tag="SLE65_002980"
     CDS             196..2385
                     /locus_tag="SLE65_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEI8450173.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            2382..4175
                     /locus_tag="SLE65_002981"
     CDS             2382..4175
                     /locus_tag="SLE65_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HEI8450174.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            4375..4689
                     /locus_tag="SLE65_002982"
     CDS             4375..4689
                     /locus_tag="SLE65_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEI8450175.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            4710..5087
                     /locus_tag="SLE65_002983"
     CDS             4710..5087
                     /locus_tag="SLE65_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEI8450176.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            5097..5870
                     /locus_tag="SLE65_002984"
     CDS             5097..5870
                     /locus_tag="SLE65_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450177.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            5892..7295
                     /locus_tag="SLE65_002985"
     CDS             5892..7295
                     /locus_tag="SLE65_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEI8450178.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            7477..8661
                     /locus_tag="SLE65_002986"
     CDS             7477..8661
                     /locus_tag="SLE65_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEI8450179.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            8658..8948
                     /locus_tag="SLE65_002987"
     CDS             8658..8948
                     /locus_tag="SLE65_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450180.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            8945..9166
                     /locus_tag="SLE65_002988"
     CDS             8945..9166
                     /locus_tag="SLE65_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450181.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            9208..9987
                     /locus_tag="SLE65_002989"
     CDS             9208..9987
                     /locus_tag="SLE65_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HEI8450182.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            10054..10548
                     /locus_tag="SLE65_002990"
     CDS             10054..10548
                     /locus_tag="SLE65_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEI8450183.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            10604..11242
                     /locus_tag="SLE65_002991"
     CDS             10604..11242
                     /locus_tag="SLE65_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450184.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            11314..11709
                     /locus_tag="SLE65_002992"
     CDS             11314..11709
                     /locus_tag="SLE65_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEI8450185.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            11693..14146
                     /locus_tag="SLE65_002993"
     CDS             11693..14146
                     /locus_tag="SLE65_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEI8450186.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            14143..16170
                     /locus_tag="SLE65_002994"
     CDS             14143..16170
                     /locus_tag="SLE65_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450187.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            16167..17189
                     /locus_tag="SLE65_002995"
     CDS             16167..17189
                     /locus_tag="SLE65_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEI8450188.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDGETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            17206..18135
                     /locus_tag="SLE65_002996"
     CDS             17206..18135
                     /locus_tag="SLE65_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEI8450189.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            18380..18496
                     /locus_tag="SLE65_002997"
     CDS             18380..18496
                     /locus_tag="SLE65_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEI8450190.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            18512..20431
                     /gene="tet(M)"
                     /locus_tag="SLE65_002998"
     CDS             18512..20431
                     /gene="tet(M)"
                     /locus_tag="SLE65_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEI8450191.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIV
                     NTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRL
                     NSRIDKVRYMFNKIT"
     gene            20529..20717
                     /locus_tag="SLE65_002999"
     CDS             20529..20717
                     /locus_tag="SLE65_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEI8450192.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(20775..21128)
                     /locus_tag="SLE65_003000"
     CDS             complement(20775..21128)
                     /locus_tag="SLE65_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8450193.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            21659..22081
                     /locus_tag="SLE65_003001"
     CDS             21659..22081
                     /locus_tag="SLE65_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEI8450194.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            22078..22308
                     /locus_tag="SLE65_003002"
     CDS             22078..22308
                     /locus_tag="SLE65_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8450195.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            22806..23006
                     /locus_tag="SLE65_003003"
     CDS             22806..23006
                     /locus_tag="SLE65_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEI8450196.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            23033..24226
                     /locus_tag="SLE65_003004"
     CDS             23033..24226
                     /locus_tag="SLE65_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEI8450197.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(24294..25859)
                     /gene="guaA"
                     /locus_tag="SLE65_003005"
     CDS             complement(24294..25859)
                     /gene="guaA"
                     /locus_tag="SLE65_003005"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEI8450198.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(25918..26841)
                     /locus_tag="SLE65_003006"
     CDS             complement(25918..26841)
                     /locus_tag="SLE65_003006"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEI8450199.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            27037..27642
                     /locus_tag="SLE65_003007"
     CDS             27037..27642
                     /locus_tag="SLE65_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEI8450200.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            27950..28966
                     /locus_tag="SLE65_003008"
     CDS             27950..28966
                     /locus_tag="SLE65_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEI8450201.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            29107..30408
                     /locus_tag="SLE65_003009"
     CDS             29107..30408
                     /locus_tag="SLE65_003009"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEI8450202.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            30454..31116
                     /gene="deoC"
                     /locus_tag="SLE65_003010"
     CDS             30454..31116
                     /gene="deoC"
                     /locus_tag="SLE65_003010"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEI8450203.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            31137..31535
                     /locus_tag="SLE65_003011"
     CDS             31137..31535
                     /locus_tag="SLE65_003011"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEI8450204.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            31601..32683
                     /locus_tag="SLE65_003012"
     CDS             31601..32683
                     /locus_tag="SLE65_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HEI8450205.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            32895..34457
                     /locus_tag="SLE65_003013"
     CDS             32895..34457
                     /locus_tag="SLE65_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8450206.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            34450..35583
                     /locus_tag="SLE65_003014"
     CDS             34450..35583
                     /locus_tag="SLE65_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8450207.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            35583..36539
                     /locus_tag="SLE65_003015"
     CDS             35583..36539
                     /locus_tag="SLE65_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8450208.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            36638..37804
                     /gene="deoB"
                     /locus_tag="SLE65_003016"
     CDS             36638..37804
                     /gene="deoB"
                     /locus_tag="SLE65_003016"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEI8450209.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            37828..38646
                     /locus_tag="SLE65_003017"
     CDS             37828..38646
                     /locus_tag="SLE65_003017"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEI8450210.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            38663..39370
                     /gene="deoD"
                     /locus_tag="SLE65_003018"
     CDS             38663..39370
                     /gene="deoD"
                     /locus_tag="SLE65_003018"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEI8450211.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
BASE COUNT        13200 a         6722 c         8056 g        11568 t
ORIGIN      
        1 aaggtttcca acaggccgaa ggcgagctcg aacaaatgct aagccaactg attgagaatt
       61 agaaacaatc tgcagtaggg aagaatcatt tacacaaaat tattgacgct cccttataat
      121 gagaactttt actaacataa tttatgataa acttactata taatcatatt aattaaatag
      181 ttaggagatc tgcttatgtt tatatctact cttcaaattc gaaattttag aaattatgaa
      241 tccgaaatct ttcgattcga taatgagaca aatactatta taggtgagaa tgattcaggg
      301 aaaaccaatg ctcttactgc attgagaatc ttattagatg atagttatta ctatagtagt
      361 aaaacactaa aagaatcaga tttttttcat ggaattcaaa atgggtggca agggcattgg
      421 attattatct ctgcgacatt tgaaggaatc agcgaagaag aatttgacaa tgagatttgt
      481 gcttccattt ctttaaattc tgaaagtcaa acaatcttag aagaattgat ttcaaatgca
      541 gataaaggtg taggtagtat ttctctattt attagaccta acaaagctat tagaaagcaa
      601 ttatttgata tttccactga attagactct catcaattta acgaatttag aaattctatt
      661 cgtctatccg actatgaatt ttactacaca tctaaatcaa atctaaattt ctgtatcaat
      721 gaaaattatg ataaattggt aggaagactc aatgacaata tagctagtaa tcctgaagaa
      781 gacgatgaag ctctgttggg ctcaagaatt gacatgtcag atattttcaa gcatatttcg
      841 gttgtttatg ttgacgctct tcgagatgtt cttagagaaa tgaaaaacaa tcgaaaccca
      901 gtcaaaagaa tcatggaaac aattgaatca aaaatatcat cagataatgt tgagtcatta
      961 aaaacaatta tacagcaatt aaatgagact attaccagtg ttcctgaaat taggaaaatt
     1021 ggcgaaaata ttaatcggca actaaatagc ataattggtt cagtgtattc tcctaatctt
     1081 cttctttcct caactatgtc agatgatatg ggttctttag caaaatttct ttcaatgaag
     1141 ccagaacaaa atatcgactt agacttacta gggttaggac atctaaatat gatttattta
     1201 gctttgaaaa tagtcgaatt tgaagcgtgt cgttcaagag aactacttaa tattatgttg
     1261 attgaagaac cagaagctca tattcatcat catattcaaa aaactctgtt cgaaggatta
     1321 aatcttcaaa aaaactatac tcagattctc atgaccacac attctgtaca tttagctgaa
     1381 gtgtctgaaa tatctcggat gaatgtatta aaatcgttta atggcaaatc tatcgttatg
     1441 aatccagcaa ataatctgaa ctcatttgct aaagaaaagt taaaaaagaa caatctaaat
     1501 ctaataaacg cagtagagag atatttagat gttaaaagaa atggattgct tttttctaaa
     1561 ggtgttatct tagttgaagg agatgctgaa gaaatactta ttcctcaaat agtaaaaaaa
     1621 ttatttggta taaacttaga cgaacttgga ataggtttga ttaatgttgg tagtacttcg
     1681 tttgaatata tcgctagctt gtttgacgat gatagaatac agagaaagtg tgctattgta
     1741 actgatttag atgaacaggc aatcccatca gaacatcgat tgtataaaag cactgcacaa
     1801 gagaaaggtc aagcaagaaa agaaaaatta tcctcccttt ttaatgaaaa caattgggtt
     1861 aattgttttt atgctaatac aacatttgaa attgagtttt tagatgtgaa taaagaaaat
     1921 attctaactt atgtcagtcc aattatagat gacgcattca aagataaaaa aacaataact
     1981 gcttataaag aagaaataca aagtgaacaa tatttagaaa gaaatttagc gatgttaaaa
     2041 ctagccaatc atgttggtaa ggggtggttt gcaattgagt taggtgaaaa aattgacttt
     2101 ttaatcaaaa ttcctaagta tattcttaat gctattgctt ttgcatgtca ggaaatagta
     2161 gatctctcaa tttataaaaa aattctactc catacaatcg acttgtacga ggaaactaca
     2221 gaattgtcag ctttatcagc tagtttaaaa acaagtgata cagctgattt gaatatagca
     2281 ataatttctt tattagagta ctttggtaaa gatgaggatg ttgtgtatct aatcaatcag
     2341 atagaaaatt acacaaaaat actttatgct gaggtttcaa aatgacaaat atcttcgaaa
     2401 aaatcgtaaa tgatttaaat ttagaacaaa aagatgttgt ggaaagtgaa gataaccttt
     2461 atgtaaatgc atgtcctggg agtgggaaaa caagggtact tacaaggaaa attgcttacc
     2521 aagcaattaa acacgatgga tcactaaaaa gaataattgc tatcacatac actaatagag
     2581 ctgctgaaga aattaaggaa cgcctaagtt tacttagtat agatgatgat attaatattt
     2641 gggtggggac aatacatcag ttttgtcttg aatttattat ttatcctttt aaaatgaatc
     2701 tctcaagagt atcaaaagga tttacaatta ttgatgatta tactcaaaga gcttacgtca
     2761 gccaaattaa taatatgctg aatttaaatc tcaaaacgta tgaactgaac aaaattgatt
     2821 tgtcactttc tcatgatttt aaaattaatg aagttcagta tactcaagtt tctgaaatgt
     2881 atcacactat gttggaaaaa aataaagaaa ttgattttga tatgatttta ctagtagcgt
     2941 ataaaatttt aactgtaaac agtaacgttg cacgtaatat tgctagtaat ataagggcga
     3001 tttatgtgga tgaatttcaa gatactagag aattacaata caatgtaata gctaaattac
     3061 ttcaaaacaa ccctcaaatt cagtcaatgt ttgttggaga tattgaccaa gcaatttatg
     3121 gatcattaga tggtatagct aaatcagttg aagaactaga aatgctaact agtcacactt
     3181 ttcaatcaaa gacgctacat ggctgttaca ggtctaatca gagattagta gacttctact
     3241 ctaattttca gagttgtcct tacgagattg aaagcagagg gaataataaa aacgaccgtg
     3301 gttttataag ttatgattgc aaagttacta aggaggattt acccaacata ataaaaaata
     3361 taataaagga aaagattgaa agcggcattc atgaaaaaga tatttgtgta cttgctcctc
     3421 aacactatcc tctgttttca ctgggtgagt atttaaagaa agaattaccg tattgcaatt
     3481 ttgatgctat aaatatatca ccaattaagg taaataatca tagtttattt ttcaagttag
     3541 caattttgta ctttactgaa tcaggtgaaa aggttcgaag aagaaagcta attgcaaacg
     3601 atattttaat tatattaaaa aatgaatttg gaatagaagt taaagattat tttattgact
     3661 tagatttatt acagctaata aacagtgtga aaagaatgta tagtggagac gacaacggtg
     3721 ttgatttata caaatttgtt accaaacata tatttgttaa tcttaatatt gacgagaaaa
     3781 attacccgtc tatttttaag cactatctat tttttattaa cgaagtagaa gatcggataa
     3841 aaaataattc attatctagt agtgtatcta gttttaagaa gatgtttaaa tctcgagatg
     3901 gtatcacact tactacagca cataaagtta aaggaaatga gtatgatact gttatcgcta
     3961 ttaatcttct aaacgggaaa attcctcatt ggaatgaaat ttttaatgtt tctgataaag
     4021 gaattagttc agcgagaaaa ctactatacg taatttgttc aagagcaaaa aataatttat
     4081 ttcttttctc agaggtgggt tattttacga gtaaaggaga cttgctttat cccactcaat
     4141 tattagataa aatagaattt gattataata tttaaaatac ctaggtagtc gttgttttaa
     4201 atatagtagg aatcggacgc tcagtacgga gcgtctattt ttttacccaa ttttgaaagg
     4261 aagtgaactt atgaaaataa aaaatcaaga atcaaaaggt cgctctcccc cctttaaaac
     4321 catcacacaa ataagattca ttcaaacata aaaacagaaa ggataggtaa aaatatggaa
     4381 cttaaatatg tcattcccaa tatggaaaaa acatttggac aattagaata tgctggtgaa
     4441 gggaacattg aacaacgtcg aataaatggc agaccaacca ttctctctcg tagttacaat
     4501 ttatactcaa cgattcaacg agcagatgat attgttgtca ttcttccctc cgaagctggc
     4561 gagaaacatt ttgaatccga cgaaaaagtc aaactcatca acccacatat taccgcagaa
     4621 ggttataaaa ttggcaatcg aggatttacc aattacatta tgcacgcaga cgatatggtg
     4681 aaagcataag aaaggaaagg tgaaaaaata tgagattagc agaaggtatt gtgattgaaa
     4741 aagaccagac atttggcaca ttgaaatttt ccgccttgcg tcgtgaggtt cgtatccaga
     4801 atgaagatgg tacggtttcc gaagaaatta aagaacgtac ctatgactta aaatcaaaag
     4861 gacaaggacg catgatacaa gtcagtatcc ccgcttctgt tcctttgaaa gaatttgact
     4921 acaacgcaga agtggaatta atcaatcctg tggcagatac cgtagcgacg gctacttttc
     4981 gaggggcaga cgttgattgg tacgtgaaag cagacgatct tgtattaaaa ggacagacaa
     5041 aacctcatca gaaatataaa aaagaagcgt ccgaaagtga aaaataggtg ttgcttatga
     5101 caaacacacc attgattttg aaagaaattc cgaaggatga agccatttct tttattcggc
     5161 aataccatta ttcaaagata ctccctagat tgtgtaaata ctttctaggg attttttcag
     5221 aagaaaaatt attaggcgtt gtggaattag gctggggtac gcaaccccta caaaccatac
     5281 gcaaactctt tcccgacagt tcccttcaaa ccacagatta tttagaaatt ggaaagatgt
     5341 gttttcttcc agaaatgaat caaaccaatt attttggcag tcaagctctt tcagctctaa
     5401 ttaagtggtt gaaagaacat acggactgtc attttttata tacactggca gatggaattg
     5461 agggaaaatg tggctatgtc tatcaagcgt ccaacttctt ttactgcggg tatttcaaga
     5521 caagtgtcta tcgtgataag cagtcatggg aaaagataca ccctcgaagt gctcgccttt
     5581 tattagagga aaatgctcgc tttgaacagg tagagaaaaa gcattggctt tcccaggcat
     5641 tttgcgaata caaagggatt gagaaaatca atggacgcat gtttcgctat ctctatccgt
     5701 tgacaaaaga agcgaaaaaa ctgttaggac acactctcta tcgacgtcat tattatccga
     5761 aagaaaaaaa tttacgcttt gaaaagcgaa tcgcttatca gaaatatgaa gccatttctc
     5821 aaccaacttt tgataaacag gctcgtatct acaatacaca attattttga taggtggaaa
     5881 ggaggatttt tatgccattg cttcatgaca gaggagagcg aatcaaagcc aacgataagc
     5941 acttggtcta tcattttgta ctaatttcat tgctggtagt ttttctagtc gtcctactcc
     6001 cttttcattg gagagcgtta caatcggtga actggcaagc agttcagtta gatacatttt
     6061 tctatcaact tcatacgcca tacttttgga gcagtattct cactgctctt tttgtatgcg
     6121 gacttatcag ctggctttat tatcactatc gtatagattc tataaaacag ttagagcacc
     6181 gtcaaaagtt agctcgtatg attttagaaa atcattggta tgaagccgaa gaaactcaat
     6241 cagagggatt ctttaaagat ttacccagca agaaaaccaa acaacgaatc cgccattttc
     6301 ctaaaatata ttatcgaatg aaagatggac taatccatat tcatgtagaa atcaccttag
     6361 ggaaatatca agatcagctt ttgcacctag aaaacaaact agaaacagga ttgtattgtg
     6421 aattagtgga aaaaacgttg aaagattctt atgtagagta tgtcctactt tatgatacta
     6481 ttggcaatcg aattggcatt gaagacgtgg tagctcaaga tggacgtgtc aaattgatgg
     6541 aatcggtcta ttgggagttc gattctctcc ctcacatgtt aattgctggg ggcactggta
     6601 gtggaaaatc ctattttatt ctcacattga ttgaatctct cctgcataca aatgcaaagc
     6661 tttatattct tgaccctaaa aatgctgatt tggcagactt aggggcggtc atgaataatg
     6721 tctattaccg taaagaagat atgttggcat gtatcaatca attttacgaa gatatgattg
     6781 atcgcagtga aaccatgaaa caacacccta actataaaac aggagaaaat tatgcttatc
     6841 ttggtttgtc tgccaatttt cttatttttg atgaatatgt ggcaatgatg gatatgctag
     6901 gtcgtgaaag taccaccgtt attcataaac tcaaacaaat tgtaatgtta ggacgacaag
     6961 caggcttctt tttaattctt gcctgtcaac gtccagacgc aaaatatttt agtgatggga
     7021 ttcgggacaa ctttaacttc cgtgtggctt tgggtcgtat gtctgaaatg ggctttggta
     7081 tgatgttcgg aagcgataca caaaaacaat ttttcttaaa acccatcaag ggaagaggtt
     7141 acgtggatac aggaaaaagt gtgattagtg agttttatac accccttgta ccaaaaaggt
     7201 acgatttctt aggagaaata ggaaaagtca ttcaaaaaaa gcaatctgag cctgtaccgc
     7261 acgaagtgaa aggtacaggt tcagacttgc tttgattggt gtggcgttag ccacgccaat
     7321 cctttagccc cctctatcta acaggggggc acaaatacaa ctgaaaacag gcaattctca
     7381 tcaaccaatg ttgatggtac aaaggattgc ggaaaatatg aaaggtgtaa actcaagggt
     7441 catagtttac atctttttta gattggaggt ttgcgaatgg aaaacgaaaa aatttggatt
     7501 aaggaattga aagaaaagcg actggcttat ggcgtttctc aaaataaact ggcggttgct
     7561 tctcatatta ccagacctta cctatcggat attgaaacag gcaaggcagt ccctactcaa
     7621 caggtgaaag aagatttact gaacgctttg gaacgcttca atcccgataa cccattggag
     7681 atgttattcg actatgtacg gattcgattc cctaccaatg atgtggctca aattatcggt
     7741 gaggttttac gtttgaatat ggattatatg ctacacgaag actttggcta ttattcttat
     7801 cccgaacact atcgtttcgg tgatattgtt gtcctagtct ctcatgatgt aagtaaaggt
     7861 gttttattag aactgaaagg aaaaggctgt cggcaatttg aaaactttct attggctcaa
     7921 catcggagct ggtatgattt ctttcaagat tgcatggaac ataaaggtat tttcaaacgc
     7981 ttggatttag ctatcaacga taaaacaggg attttgaata ttccagattt ggcaaagaaa
     8041 tgtaaacagg aagaatgcat ttccgtcttt cgaagcttta aaaattatcg cagtggtgaa
     8101 ttggttcacc gtgatgaaaa accatacatg ggaaacacac tttatattgg ctcattaaaa
     8161 agtgaagtct atttctgtat atatgagaaa gattatgagc aatacgtgaa aaatgatgtt
     8221 cccttagaag acgcagaagt aaagaatcgg tttgaaattc ggttaaaaaa tgaccgagcc
     8281 acccaagcca tgaaagattt attggcacat caacaggcgg aaaaaacagc ctttgaaatt
     8341 atcaatcgct atatccgctt tgcagataaa gacgacacta aacgtcggag tgattggaaa
     8401 actaatgaac gttgggaatg gtttatcggt aaaaatcgtg gagcattacg cctaaccaca
     8461 cagccagagc cttattcttt tgaacgaaca ttgaactggt tacatcatca agtcgcccct
     8521 acattaaaaa tcgcaagcat tttagatgtt ctcaacggta caaccattat ctccaccatg
     8581 attcaggaag ccaaactgac agaaaaacat gagaaattaa ttgaacaaca acatctagcc
     8641 atggaggatt tgattacatg agccttttaa caaaagaatt aaagaagtta gggtttcagt
     8701 gtggcattga gtttcaagcg tatatacaaa atacagggaa atatacgtct ctcattattg
     8761 agggaaaacg gcaagctggt gataccatct atacctatga tttttacaag gtgagatttt
     8821 ataataatta taccaatcga gtaaccgtct atggagagca tttaacccct tttcaattat
     8881 taaggcgtgt aaaaagctat atctattatc gagaaaaata tcttaaggaa aggaggacaa
     8941 tcacatgaat tttgggcaga atttgtacaa ctggttcttg gataatgcac agtcattggt
     9001 attgttagcg attgttgtca ttggactgtt tttaggtttt aaacgagaat tttcaaaact
     9061 cattggcttc ttgattattg ctctaatcgc cgtcggactt gtgttcaatg cagctggcgt
     9121 gaaagatgtg ttattaaact tatttaaccg aatcattggt gcttaacaga tatttttcat
     9181 gataaaatag gaagtatata ttttgttatg aaaggattta tgaatatgtt tacaaatgat
     9241 caatttaaat ctcttttaat taaaacatta gaaagaaaga gctcttcaaa ttattatgaa
     9301 ggaggtaacg agattgtttc taaaatgaaa atatcagagg taactttaga tgagactgac
     9361 gattttactt attataaagg atataaaaag ggctggaata cgctttgcac atatcttaaa
     9421 ataagagttc cttttgatga tttagacttt tttgaaagtc ataaagattt gattacccag
     9481 acagcaagct ccatatatga taaacaaggt gataatgtat tagtggatac tattttagta
     9541 ccacttccag agaattacga agtaattaac tttagtcagt tgaaaattag tgatgtggtt
     9601 tcacaagcta ttgaagacgc tgagtctttt atgagtaatg gtgaatatca acgtgccttt
     9661 gacagagttc acactgcttt tcatggatat ttaattgaaa tactaaaaaa atatgaaatt
     9721 acagttccta gagacgaaaa tctatctaaa ttatatagta ggatacaaca attaattgaa
     9781 aaagaaattc aacctactga acttgctgat atagtgaaga caacgataag gtcatcaaat
     9841 ggaatgatta gctctcttaa tgaagcaaga aataggcatt cacttgcaca ccctaataca
     9901 aatattattg gaaagagaga agcaaaacta ataataggta tttcaagtac agttacagat
     9961 tatattagcg gataccttga taagtagcgt cattaactga ttgctacttt ttttatgact
    10021 atttttataa aaaggatgtg ataagaattg gaaatgaaag tctatgtggc aaatttagga
    10081 cggtataatg aaggtgaatt agtcggagca tggtttactc caccaattga tgaggaagaa
    10141 atggcagaaa gaatcggttt aaatgaggac tacgaagaat atgcaataca tgattttgag
    10201 cttccttttg atgtggacga atacacgccg attagtgaaa tcaaccgtct atgtgaagcc
    10261 attcaagaaa tcgaaggtac acctatttat aatgaactca aagaaattca aggcatgtgg
    10321 tttagtagct tggaagaatt actggaaaac aaagaggata ttcattgtta tagtgattgt
    10381 gattcgatgg aagatgtcgc ccgttattac gtggaagaaa caggacagct tggtgaagtc
    10441 ccttccaatt tacaaaatta tattgactac caatctttgg gacgtgatat ggaaatagag
    10501 ggtaattacc tagttacctc tcatggggta tttgaatatt gtcagtaagt ttaacaatcc
    10561 gtgttataat taaattaata aatagcacgg agaggtataa attatggtaa atgtatttga
    10621 aaatcttaaa ctattaaaac tagacatgaa agataaaggc tgggtgatag attcctttta
    10681 ctttcgttac aaacagcaaa attatattgt acttgttaag ctatttgaaa aagaggaaaa
    10741 agttccagaa tatgctctgt taaaactaga atttttaaag gaaaacgatt tttcagatat
    10801 gctagctgtc tatgctaatt cggtaaaatt atatacagac acgaaaacaa taagagaata
    10861 ttttggtatc gaatacagta gtaacttggg agatgtttta tttcaattta gccaaactct
    10921 tgctcgattt attccgacag aagttagtga gaagaaaaat gaagaccaaa aagaagccat
    10981 gtgtttctca ttaagtcaaa gtgattcaga agatcccaga aaaaaatatt gtttttcagt
    11041 tagaagaaat cctttaaagg gaaatggtga gctgggaaaa cgaagtcctt ttaatgacaa
    11101 taaaacgaga ttgtatagac ccagcttata tgaacgatta gggtcagata ccaatttaag
    11161 tttcagatat tcaatgaatc cagatgatga agaaactgat gaaggtatta ttgcaaaatg
    11221 gacaaaaaat aaaattgaat agttaaagca ttgaaagagc aatcacctat tttgattgtt
    11281 ctttttctat ttttacggaa aggacgtgaa gacatgaaaa aaataagaag ttacaccagt
    11341 atttggtcag tagaaaaagt gatttatgcg attaatgatt tacaactccc tttcccaatt
    11401 acctttacgc aaatgacatg gtttatcgtt tctttgtttg tcgtcatact ctttggcagt
    11461 ttaccaccac tttctctgat tgacggagca ctactcaaat acttagggat tcccattgtt
    11521 ctcactgggt tcatgtgcca aaagaccttt gacggaaaga aaccctatgg atttctaaag
    11581 tctatcatta cctatgctct acgccctaaa gtaacctacg ctggcaaaca aatacgatta
    11641 aaaaaagaaa caatgaatga atcgattacg attgtaagga gtgaacaact agatggcata
    11701 tccgattaaa tatatggaag ataatctcgt atttaatcat gatggcgaag tattcgctta
    11761 ttatgaatta attccctata attacagttt tttaagttcc gatgaaaaaa ttcaagttca
    11821 tgataatttc tgtcaattga ttgcccaaaa tcgtgatggc aagattcatg ctctgcaact
    11881 agcaaccgaa tcaagtattc gagccacaca ggaacaatcg aaaaaagaaa tcactggacg
    11941 attaaaagag atagcttacg aaaaaataga tgaacagacc gaagcgttaa tttctatgat
    12001 tggtgacaat caagtagact atcgcttttt tattggtttt aaactctacc tcaatgaaca
    12061 ggaagtatcc gtaaaaaatg ttgggaaaga aattcaaaaa gcatttgcgg aattctttca
    12121 tggtgtgaat cacaaattaa tgggcgattt tgtttctatg cctatggcgg aaatcgaacg
    12181 cttttctaag atggaacagt tgttagaaag taaattatcc agacgctttc agattcgtaa
    12241 attggagaaa gatgattttg gttatattat tgaacatctt tacgggcaaa caggtgtccc
    12301 ttttgatgac tacgactacc atttaccgaa acgatacgaa gataaaaaag tgttggtaaa
    12361 gaaatacgat attctcaaac ccactcgctg tttaatcgaa gaaaatcaac gctatttacg
    12421 gattgaacag gaagatacca ctacttatgt ggcgtatttt acaattaata gtattgttgg
    12481 tgaattggat ttccctaata gtgaaatttt ttattaccag caacagcagt ttactttccc
    12541 cgttgatacc agtatgaatg ttgaaattgt cgccaataaa aaagccttat ctaccgttcg
    12601 caataaaaag aaagaactga aagatttaga tagccacgca tgggaaagcg acaacgaaac
    12661 cagtactaat gtggtggacg ctttagaatc tgtcgatgaa ttagaaagta atttagacca
    12721 aaccaaagaa tctatgtaca aactaagcta tgtggtacgg gtatcagcaa agaatttgga
    12781 cgagctgaaa caacgttgtg atgaagtaaa agatttttat gatgatctgt ctatcaaatt
    12841 agtacgacct tttggcgata tgctaggctt gcataatgaa tttattccct caagcaagcg
    12901 atatatcaat gactatattc aatatgtcac gtcggatttt ttggctggtc ttggtttcgg
    12961 tgctacacaa atgattggtg aaaattctgg tatttacgtc ggttacaatc tcgatacagg
    13021 cagaaatatt tatctccaac ctagccttgc aagtcaagga attaaaggct ctgtaacaaa
    13081 tgcattagcg tccgctttta ttggttcatt aggtggcgga aaatcattct ctaacaatat
    13141 gctggtctat tattcagtac tctttggcgg acaggcaacc attgttgacc caaaagctga
    13201 acgtggtgaa tggaaagaaa ccttacctga tattgcccat gaaatcaata ttgttaatct
    13261 cacgagtgag aacgacaata aagggttact tgacccttat gtgattttaa aactcccgaa
    13321 agattcagaa agccttgcca ttgatattct cacgttctta acaggtattt ccagccgaga
    13381 tagcgagaag tttcctgtcc tgcgtaaagc tattcggagt gtaactcaaa gcaaacaacg
    13441 agggttgtta ttggtgattg atgaattgcg aaaagaagat acgcccatca gcaatagtat
    13501 tgctgaccat atcgaaagct ttgtcgatta tgattttgcc catctgttat tcagtgatgg
    13561 cagtgtcacc caatccatta gcttggaaaa acaactcaat attattcaag tggcagattt
    13621 ggtcttaccc gattccaata gctcttttga agaatacact accatggaat tattaagtgt
    13681 ggcaatgctg attgtcatta gtacctttgc tttagacttt atccactctg accgttccat
    13741 ttttaaaatt gttgaccttg atgaggcttg gagtttttta caagtggcac aaggaaaagc
    13801 tctatctatg cgattggttc gagcaggacg tgccatgaat gcaggggtct atttcgttac
    13861 tcaaaacgcg gacgatttac tagatgaaaa gatgaagaat aatattggct tgaaatttgc
    13921 ctttcgttcc actgacctag tggaaatcaa aaagacctta gaattttttg gtgtggacaa
    13981 ggaagatgaa aacaatcaga aacgcttacg tgaattagaa aatggacaat gtttagtttc
    14041 agacatctat ggtcgtgtag gggttatgca gtttcacccg atttttgaag agttgcttca
    14101 tgcctttgat accagaccgc ctgtgcgaaa tgaggtggaa gaatgacaca aaaacaaaag
    14161 aaatttcttc actatagttg gataacgctc ctttgtgtgg gcgttatttt acttttatta
    14221 ggcacgctgg gcaatgcagt acaagcgaca ggcttagttg atgaaaccat tgatacaagc
    14281 aatgaatact ccaagtatgg tttgaatcaa tatcagcttg attattatgt ggacaatagc
    14341 tggggctggc ttccatggaa ttggagtgat ggcataggac aatcggtgat gtatggattg
    14401 tatgccatta ctaattttat ttggacaatt tctctttatc tatcgaacgc cacaggttat
    14461 ttggtgaaag aagcctatgc cttagatttc attagtcaaa catcccaagc aattggcgaa
    14521 aacatgcaga cgattgcagg cattacaccg aatggctttt ccagttcagg gttttatgtc
    14581 ggtttcctcc ttctttttat tctcattgtt ggaatctatg ttgcctatac aggattggtt
    14641 aagcgagaaa cgacgaaagt gatacgagct gttttaaact ttgtcgtggt gtttattcta
    14701 tcggcttcct ttattgcgta tgcacccgat tatattgcga aaatcaatga tttttccaaa
    14761 gatgtcagta ccgccagtct gaatattggg acaaaaattg ttcttcctaa cacggatagt
    14821 caagggaaag acagtgtgga catgatacgt gacagcttat tctctgttca agtaaagcaa
    14881 ccatggctat tgcttcaata tggctccact gatgtagaag cgttagggga agaacgtgtg
    14941 gaaagtttat tgtctaccag tccagataca aacaatggtg aagatagaga aaatgtagtg
    15001 attgaagaaa ttgaagatca tgacaatacc tatttaaccc taccgaagac gatttccaga
    15061 ttaggaacag tcttcttttt gtttgtattc aatattggta tctcgatttt tgttttcctt
    15121 ctaacaggaa tcatgatttt ttcgcaagtg ctatttatta ttttcgctat gtttttgcca
    15181 atcagtttcc tattaagtat gttgccgagt tttgatggca tgggcaggca tgccattacc
    15241 aagttattta atgtgattat gacaagggct ggtattacct tgattattac cgttgccttt
    15301 agtatttcca ctatgcttta ttcgctgtca gcaagttctc cctttttcat gattatgttt
    15361 ttacaaattg tgacctttgc agggatttat tttaaactgg gcgatttaat gagcctattc
    15421 actttacaaa gcaacgactc tcaaaacatg ggcagacaag tgtttcgcag acctcgtcaa
    15481 atgatgaatc gacaaaccag aagatttcaa cgcagtatga gtaagatttt tcgtggaaaa
    15541 gcagggtcaa cgaagcaaaa gacaatgaca acaaagcaga atcaaaccaa taaagctaac
    15601 catactcgtc aaaatgaacg gactacacca aagaaagaaa cagcactttc caatgtgaaa
    15661 aagcaacaag gcggtatcgg gcaacgatta ggtgaaaaga cagcccatgt attggacacg
    15721 aaaaatcgtc tagtcaataa aagaaagcag gcaaaacaac agatacaggc gacaccaacc
    15781 catgtcaaat atgcccttca tcaaggaaaa gagaatgtca ctcataatgt aacagacttt
    15841 aaacaatcta tggcagatac caaagctcaa cgcaaacaac agcgtatgaa ccagcaggag
    15901 caaaaacgaa agaacattgc tcaaaagcgt ttggagctgg ataaagcaaa agaaaaaaga
    15961 cgaaaagaaa acccatcatc tcctgttcag aataaccagc agcatgttcg caagcgtcag
    16021 caaaccgtca cgcctgtttt gtcacaaaac actaaacgtg aaaatcatca gcgaccattg
    16081 aaaaaagagc aaaaacaaaa gacaccaccg aagcaattca atcagaggaa gctaaataaa
    16141 agaacggata agcgaggaca acaaacatga agctaaaaat aacagtgatt tgtagtgtgg
    16201 tcttctctct cttctttttt ctcttattat tcctagtcat tttctttgca gatgatacgg
    16261 acagtggcga aaacaacaag gattcttcta ttccacaagg cggtgtgacc gtttcaccag
    16321 aagtgttggc acaccgtccg ttgattgaaa aatatggtaa ggaatatggg attgaagact
    16381 atgtttctta tatcttagcc attatgcaag tggaatcggg cggtacagca gaagatgtta
    16441 tgcaaagttc cgaatctttg ggtttaccgc ccaacagttt gagtaccgaa gagtccatca
    16501 aacaaggggt taaatatttc agtgaattat taaccagtgc agaacaacaa ggagtggata
    16561 tagattctgt tatccaatct tataattatg gcggtggctt tttaaattat gtgaggagtc
    16621 atgggaaaaa atatacctat gaattagccg aacagttttc taaagagaag tcgggtggtc
    16681 aaaaagcaga ctatcccaat cctatagcca tacctgtgaa tggtggttgg cgatataact
    16741 atggaaatca gttttatgtt cagttggttt cacaatacct aaccgacact tccccaacag
    16801 aatttgatgg tgaaaccgtg caagtcatta tggacgaagc cttgaaatac gaagggtttc
    16861 cctatgtctt tggaggggcg tcgcctacca cctcttttga ttgtagtggc ttaatacaat
    16921 gggtgtatga caaagctggc atttctctcc ctcgtgtcgc ccaagatcag tatgacgcta
    16981 cgcaagaaat ctctatggaa gaagcccaag caggcgacct tatcttcttt cattcaacct
    17041 ataatgcagg cacatatgtg actcatgtgg cgatatattt agagggaaat cgcttttatc
    17101 atgcaggcga cccaatcggt tatggcgact taagcagtcg ttattggcaa gaccatctga
    17161 ttggggctag acgtgttatt cataactaag aaaggaatga atcaaatgat tataaaaatc
    17221 gagcgaaaag aaaagaagga gaaaccaaag aaatctaaaa aaccgagcaa gcaaagaaaa
    17281 gttccgatga ttaaagttgg cacgcataag aaattaacct ttgttttatg ggttttattg
    17341 attggtagtg tcggatttgg aatctataaa aattttactg ccattgacac tcatactgtc
    17401 cgtgaaacag aaatcattaa acagcagatt gtcgatacca accaagtaga aagttttgtg
    17461 aaatcctttg cgaaagacta cttttcgtgg caacaatccc aagaagccat tgataaacga
    17521 aatgaaaaat tgacccatta tttgacggaa gaattgcagg tattaaatga agaaatgatt
    17581 cgtaaggata ttcctactag ttctagtgtg aacgatatac aggtgtggca ggtttctcaa
    17641 gtgaatgaga acacctttga ggtactgttt tctgttgaac aagttattac cgaagacaaa
    17701 gacaaggaaa ctatatcgtc tagctttcat gtggttgtcc atatagatga atcagataat
    17761 atggttatta tcaaaaatcc gacaatgagt aagaaacctc aaaaatcgga ctaccaaccc
    17821 aaacagctag aaagtgacca tacagtagat acagaaacga tggacgaaat cactagcttt
    17881 ttagaaacgt tcttccagct ctatcctacc gccacagaaa aagaattgac ttactatgta
    17941 agtaatcatg tgttacctat gattaacaag gaatatgttt tcgaggaatt ggtgaatcct
    18001 atctttacca gaaaagataa ccaagtaatc gtgaatgtcg ctgtgaaata tttagatcaa
    18061 gaaacaaagg caacccaaat ctcgcaattt gagttgatat tagaaaaaca agataattgg
    18121 aagattgtaa aataacaaat attggtacat gattacagat actttgtaat catgtactct
    18181 ttttgataaa aaattggaga ttcctttaca aatatgctct tacgtgctat tatttaagtg
    18241 actatttaaa aggagttaat aaatatgcgg caaggtattc ttaaataaac tgtcaatttg
    18301 atagcgggaa caaataatta gatgtccttt tttaggaggg cttagttttt tgtacccagt
    18361 ttaagaatac ctttatcatg tgattctaaa gtatccagag aatatctgta tgctttgtat
    18421 acctatggtt atgcataaaa atcccagtga taaaagtatt tatcactggg atttttatgc
    18481 ccttttgggt ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc
    18541 tcatgttgat gcaggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat
    18601 tacagaatta ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg
    18661 tcagagagga attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt
    18721 gaacatcata gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc
    18781 agttttagat ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg
    18841 tatattattt catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat
    18901 tgaccaaaat ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc
    18961 cgaaattgta atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac
    19021 cgaatctgaa caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat
    19081 gtccggtaaa tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa
    19141 ttgttctctg ttccctcttt atcatggaag tgcaaaaagt aatataggga ttgataacct
    19201 tatagaagtt attactaata aattttattc atcaacacat cgaggtccgt ctgaactttg
    19261 cggaaatgtt ttcaaaattg aatatacaaa aaaaagacaa cgtcttgcat atatacgcct
    19321 ttatagtgga gtactacatt tacgagattc ggttagagta tcagaaaaag aaaaaataaa
    19381 agttacagaa atgtatactt caataaatgg tgaattatgt aagattgata gagcttattc
    19441 tggagaaatt gttattttgc aaaatgagtt tttgaagtta aatagtgttc ttggagatac
    19501 aaaactattg ccacagagaa aaaagattga aaatccgcac cctctactac aaacaactgt
    19561 tgaaccgagt aaacctgaac agagagaaat gttgcttgat gcccttttgg aaatctcaga
    19621 tagtgatccg cttctacgat attacgtgga ttctacgaca catgaaatta tactttcttt
    19681 cttagggaaa gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga
    19741 gatagaacta aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata
    19801 taccattcac atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc
    19861 accgcttccg ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa
    19921 tcaatcattt caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata
    19981 tggttggaat gtgacggatt gtaaaatctg ttttaagtac ggtttatact atagccctgt
    20041 tagtactcca gcagattttc ggatgcttac tcctattgta ctggagcaag cctttagaaa
    20101 agctggaaca gaattgttag agccatatct tagttttaaa gtttatgcac cacaggaata
    20161 tctttcacgg gcatataacg atgctcccaa atattgtgca aatatcgtaa atactcaact
    20221 gaaaaataat gaggtcatta ttattggaga aattcctgct cgatgtattc aagattatcg
    20281 caatgattta acttttttta caaatgggct tagtgtttgt ttagcagagc taaaaggata
    20341 tcaggttacc actggcgaac ctgtttgcca gacccgtcgt ctaaatagtc ggatagataa
    20401 agtaagatat atgttcaata aaataactta gtgcgtttta tgttgttata taaatatggt
    20461 ttcttattaa ataagatgaa atattcttta atatagattt gaattaaagt ggaaaggagg
    20521 agattgttat tataaactac aagtggatat tgtgtcctat ttgtggaaat aaaacaagac
    20581 tacgaatacg agtggatact atacttaaaa atttcccttt atactgcccc aaatgtaaga
    20641 acgaaacttt aattaatgtt caaaaaatga atataataac aatcaaagag ccagacgcca
    20701 agacgcagag ccgataattt gagaaatgaa actctcatct tatcggctct ttttgtttat
    20761 ctgaatttta ctgactagcc ttcaatattt cttgcttcat tgataccttt tgctagtgct
    20821 tccattaagg atagttcttt gtctgtaaag ctatccatgt atttttctac ctgtaacctt
    20881 cgagtgcttt taatcaaatt atctgtaggt aagaaaaatt catcaataga tacatggagt
    20941 aatgatacaa gatcatacag cacttgtgta cttgggtgtt gtcctttgtt ttctatattt
    21001 gttaaataac gtgggtcaat ttcaatcatt gttcccactt gttcacgagt gagaccccgt
    21061 ttcattcgag cctctttaat cgctaaacca acggctctaa aatcgtattt atcttctttt
    21121 ttacgcatac taaatcacct ctatacattt tactgttcct atataaccat aaacaggtat
    21181 agaaaaacat gttatatagt ttatgagttc ctatagaaca ctgtggaatt tattaatgcg
    21241 atgaatccaa tttcaaatag aaaggtcgct gattttattt acctatacaa ctttataaaa
    21301 tttagtcata ctcctagaaa gtagataaaa ttggtgactt aatggaggga aaagtcgcca
    21361 tgagaaagat aatctgtcat ctagttctct taattaagtt cttatcaaaa aaacttatcc
    21421 acctgtactg gatagatatg accatcaatg tggttttgca gattacatag atagaaaaat
    21481 caaagcatat gaacagagaa aacaatctgt ttatgtgctt ttttggtcac ttaataaata
    21541 tcttttagga tttctcttca tttatgcaac aaatccccct ttcgtgtcgg ggtttagtat
    21601 gaagggagat aaagaagcac atgccactcc ctttcacgac agaaaggggg tgaaaagcat
    21661 gaaaccatct tcttttcaag aaaccataga aaatcagttt gactatatct gcaaacaagt
    21721 tattgaagat gaacgaaaag attacttcaa acatctagac agactatcag caaaagaagt
    21781 ctcgttttct gatatagata actaccttgt caactctttt tctactgttg atacgtacgt
    21841 cactgatttc caactattta aattatttgg attaagaatc aatgttgaaa gtgatttatt
    21901 aagtgaagcc ctgcgtcatc tttcagagaa aaaacggaac attattttac ttcattactt
    21961 tatggatatg agtgatgtgg agattgcgga gttactaaat ttgaatcgtt cgactgttta
    22021 tcgtcatcga ataagtggac tagccatgat taaagaattc atgaaggagt gtaaagaatg
    22081 aaaacagctt atccaagggt tcccttcccc ctcattgtaa aggcgacaga tggcgacgtg
    22141 gaagcaatta atcagattgt taaacattat cgagggtata cctcaaaacg ttcattacgt
    22201 cgcatgacag acgaatatgg aaattctcat atggttattg atgaaaccct acgtggcaga
    22261 atggaaacga aactcatctc taagatttta tcgttcgaaa ttaaatagtc ccattttttc
    22321 gtggaagcgt gtcgaatcgt atccacgctt cccgatttgg gaggtttgtt attccatcaa
    22381 agcatattgt gtgttcagta ggttttgata ggctaacaag ccaaacgttc tttgacaacc
    22441 aaataaaggc aatcgaatac gtttcggtaa gaaaagagct gatgaactaa cacgccatga
    22501 cctacaaaat tagtgagcga ttcatgttag taattcgaaa gtaatcttta gcaggattgc
    22561 tgccatgact ttcttatcgt gataatgata ctcccgtata gccatagtcc gagcgttaga
    22621 agcgtcacag gcaatgggta cggctacatg agaaccatgc agaagtgaaa ttcctgtgag
    22681 ctttgctaga gctgttcgat tgctaagata ttcttctctt gtcagtgtat tattataaaa
    22741 ctatttgata taattatagg tgaatattgg agttttccta gcctataatt gggaaaggag
    22801 taataatgat aacggtcaca aaaaaggatt tagttgagct aggatatgga acttcttttt
    22861 cagcagacat cataaaaaaa gcaaaagaat tgatgattac aaaagggcat atctactatc
    22921 aatctcgaaa gctagataga gtccctcgtg aagctgttga agaaattcta ggaattcggt
    22981 tttcaaatga aaacaggtct gagtagtttt tgcacagtaa ggagtaaaaa ctatggttaa
    23041 agacccaata aaaaaagcaa agaatggaac ctattatttt cgtgcaaatc taggttatga
    23101 ttctaaaggg aaaaaaattc aaaaatatcg tagtggattc actactaaaa aagaagcaag
    23161 agaagaatat tcgaaactgc tattgatgaa accagaagaa ttaagtgaga ataaggataa
    23221 aatgacgttt aaacattata tctttgaaat tttccttcca tggtataaga cacaggtaaa
    23281 gctcagaaca tatgaaaatc gcttaccaac tattaagaag catttctctt attttgataa
    23341 aatggctgtt tccgatattg agcctattga tgtgcaaaat tggcaactaa aattatcaaa
    23401 gaagtgtaag tcttcttatg taagagctgt tcaaggacta ttttcagttg ctatggatcg
    23461 agcaattgtc cttgggataa ccaccacaaa tccatctaag attattggca atgtgaaaaa
    23521 gcaaaagtct aaaattgaat tttggacaaa agaagaattt gaaaaagtaa tctctctaat
    23581 ttacaaagaa gattactatc aacacttttt atttatctct ctgtggtttt tatttatgac
    23641 tggaatgcga attggtgaag ctactgccat tcaatgggaa gatattgatt ttgactcagg
    23701 agtactaacc atcaacaaaa cactctatta caagaatcaa tcgaattata gatttgttga
    23761 accaaaaaca aaggcgagcg ttcgtcatat tgtattagat aaatgcacat taacttattt
    23821 atccgaatgg aaggaagtac aacaaaatct aattcagaca gactttgtaa tgagctataa
    23881 cggtattcct acccaaaaac atacactatc atatgctatt gaacgctatg ctaagctggc
    23941 tggtatccat cgaatcagaa tccatgggtt acggcattct catgcttcct tgttaatcag
    24001 tatgggagaa aatccactta tcattaaaga tcgtctagga cacgaagata ttgagacgac
    24061 tttaggaacg tatggacatc tttatcctaa cagtaatttc gaggtagcta acaaattaaa
    24121 tggagccatt tcctttaaag aagcaaaaca aaattatgat acttcaccaa agaatcaatt
    24181 tactgtagac tacttgcgaa acaaagaaat gaaaaaagtg caataaaagt gcagtaaaaa
    24241 gataagaaga gccagaaacc cttggtataa gaggatttct agctctccta caactattcc
    24301 cactccactg ttgctggtgg tttagaagtg atgtcataca cgatacggtt gacgtgggct
    24361 acttcgttta cgatacgtac agagattttt tgcaagactt cccatgggat acgggcaaag
    24421 tcagcggtca ttccgtcgat tgaagttaca gcacggatac cgactgtgta gtcgtaagta
    24481 cgtccgtcac ccataacacc gacagagcgg atccctggaa gaacagtgaa atattgccag
    24541 atatcacggt caagtccagc agctgcgatt tcttcacgca agatagcatc agattcgcgt
    24601 acgatttcta gcttgtcttc agtgatttcg ccaagaacac gaataccaag accaggacca
    24661 gggaatggct gacgccaaac gattgaatca ggcatgccta actgagtccc taattcacgg
    24721 acttcgtctt tgaataatgt gtttaatggt tcgatcaatt caaattgcat atcttctggc
    24781 agtccaccta cattatggtg agatttgatc gtctgtgctg tttctgtacc agattcgata
    24841 acgtcagtat acaacgttcc ttgtgctagg aaagagacgc cttcttcacc agcaagtttt
    24901 gttgcttcgt catcaaaaac atatacgaat tcattcccaa tgattttacg tttttgttct
    24961 gggtcagata cacctttcaa cttgtctaag aagcgatctc ttgcatcgac tttgatgatg
    25021 ttcaagccga attttccgcc tagactttcc attacttgtt ccgcttcgcc tttgcgtagc
    25081 agaccgtggt caacaaagat agatgtcaat tggtcaccga tcgctttttg taaaagaacc
    25141 ccaacgacac tagaatcaac gccacctgaa agaccaagca agactttttt gtcaccaact
    25201 tgttcacgga ttttttctac ttgcatatcg ataaagttat ccattgtcca gttaccttca
    25261 cagtgacaaa catcaaaggc aaagtggcgc agcaattcga ttccgtattc ggaatgacgt
    25321 acttctgcat ggaattggat accataaaaa ttacgtgttg tgtcttggat agaagcaatc
    25381 ggacaatctt tgcttgttcc gactgtttca aagccttcag gaactttagt taccaagtca
    25441 ccatggctca tccatactgt ttgttgtttt ggtgtttctt taaacaagac agcttgatcg
    25501 cttgttactt ctaacaaggc tttcccatat tcgcggtttt tagcaggctc tacggaaccg
    25561 ccaagtttgt acgtgatcaa ttgcatacca tagcaaatcc ctaatacagg aatacctaaa
    25621 ttgaagatct caggatcgat cccaaatgca ttctcatcat atacactgtt tggtccgcca
    25681 gaaagaatga ttccctttgg attcatcgct tttacttctt ctgcagtaat gcggtggctc
    25741 aataattcgg aaaagactcc aagatcacga atacgtcttg tgatcaattg gttatactga
    25801 ctaccgtagt ctaatacgat aatcttttca acgttcgtca tatcggcaac gtttgtcaaa
    25861 tttattaccc ctatcccttt aaattttatc tcaaaatagt caaactattt taaaatgcta
    25921 atattttcgc atgaaaatcg aatcgatgat atgattttca gttttatgga gaattatatc
    25981 ggctcttcct cgtgtaggca agatatattc ctgtaaattt ttcaaattca catttttcca
    26041 tacatctttt gccattttaa aggcttcttc acgatctccg atagcaaaac gataataata
    26101 attctctgga ttttggaaag ccgtatccag taacgcacca aaacgatcca aataccattt
    26161 ttcgatcagc acgggatcgg catcgacata gacagaaaaa tcaaaaaagt cgctgacgta
    26221 gatttgctga ttcgcaggta attgaagcgt attgatcccc tcaacgatca agatatcagg
    26281 ctgctggatc aattcgtact tgtctggaat gatatcatac acatcatgtg agtaaacagg
    26341 tacttttatc tcttcctgac cagattttac acggttcaag aaatcgatca gcatctccat
    26401 atcataactt tcaggaaatc ctttacggtc catgattcca cgctctttta atatacgatt
    26461 tggataaaga aatccgtcag tcgtgatcag ctgaacgttt cttcgtttga aggtacgaga
    26521 caaaatcgtc tgcagcagtc tggctgttgt actttttcca acggctacac ttccggcgat
    26581 cccgataata aaaggcggta cttctacgta tttatgaaga aataaacctt tactcaagaa
    26641 caaagattca aattctttca tataaagata aatcagatga gcaagaggta catagatatc
    26701 tcgaacatcc tgcatggaaa tgcggtcatt caaacttttg atattatcta gttcatcttg
    26761 tgtcaaaggt gcttgcccat tacgataaaa ttctcgccat tcttctcttg ccacacggta
    26821 gtagttcatt ggatcattca tattagcctc ctgcgttctc ccatcaatgg aactatttta
    26881 acacaaaata aacgcaaacc ccaccactta agagagattg ccgatctttt tgtataatct
    26941 ttataataga aagaaacgga gtcttattct tgacttgcgc acggatacat aaaaggatag
    27001 actgttgtca tgaaagaaat gagaaggatg gaagacatga caaatcatta ctattctgaa
    27061 cgcccagata cggcgcacga ttttgaacaa tgggcttttg agttaaaagg cagaaccttt
    27121 caatttgtaa cagattctgg tgtattttca cgtgaaacag tggattatgg ttcacgtgtc
    27181 ctgattgatg ctttcgattg ggaagagtta cctgatgaag gaaagatctt agatgtggga
    27241 tgcgggtatg gaccgattgg gttagctttg gcatttgcga cacagcggtt tgttgaaatg
    27301 gtcgacatta atgaacgagc ggtaagtcta gcgcaaggaa acgcaaagcg taaccaaatc
    27361 gaacatgttg atatccatca atcgaatatc tatgaagcag ttcatgaaga aacctatgca
    27421 gctatcgtaa gcaatccgcc gatccgtgct ggaaaaaaag ttgtacatga aattttgaca
    27481 ggcgcatatc ctcggttgaa gaagggcggt acactgacaa ttgtgatcca gaagaaacaa
    27541 ggagcgccga gtgcgcaaaa gaaaatggaa gaaacatttg gtaatgcaga aatcgtcaca
    27601 aaagataaag gatattatat catcaaaagt gtgaaagaat aactagctga aaaatagtgg
    27661 agcgacgaaa gagtggaact gggcgtgcat gtacgggtac gtatcagttc tttttttgtt
    27721 gagaagtttt taaaaacaaa gaactatttt ttcttcaaaa agaaatagta ggaacagagt
    27781 cgttgttttt tacgataaaa taaataagat acagaacttg tatagaaggc tgccaagtcg
    27841 gtagataaag gaggttttta tcaaaaaaca tactttcctt ttttctctat tcttttcttg
    27901 ggggttttgg tacactgata gggaatttag atagaaggga gccaatagga tgaagctgac
    27961 catcagagat atcgcagaaa tggcaggcgt atcagtaaca actgtctcac agattttgaa
    28021 taacaaagga agcagattta gtgataagac aagaaaaaaa gtgttgtcga tcgtgaatga
    28081 acatcattat aagcccgatt atttcgcttc aaatgtgatc aatcgacatt caaagaccat
    28141 cggaatgatc gtccctgatg tcactgattt cttcttctcc aaactgatcg aaggtgtaga
    28201 gagctatttg aatcctttgg gctatgtgat catgttatgc aattctcgtc atagccaaga
    28261 aaatgagatc aagtatttac aagagctttc ccaccgctca gtggacggaa tcttgctggc
    28321 cacaccaaat attttacctg agaaatatgc attagacagc ggtttttatc aaaaaatgcc
    28381 aatcatttta atcgatcgcg gattgaatcg tcgggataac ggacggctta tcgtaaagga
    28441 atatgagggc gcctatcaag ctgtttcgct gtttattgaa aatggccata cgaagatcgg
    28501 catgctgaag gaaaccactg gatactatca attagaagaa cgtttcaacg gatatcgtca
    28561 tgcgctgaaa gatcatggcc tgccttttaa tgggaaattt gttgaacatg gagagttgac
    28621 tgtccaaggt ggatatactg catcaaaaaa attactcaaa cataaagata tcacggctat
    28681 tttttgcggg aatgatgcca tggcgatcgg atgctatcag gcgatcgatg aattgggcaa
    28741 aaaaatccca gaagatatct cagtcatagg attcgatgga ttaaagctgt cagaatacat
    28801 gattccgcaa ttgacgacag tgcagcagcc aagttttgat attggatttt atgctgcacg
    28861 tttcctgatc gatacgatcg aatttcctca aagaaaagtt ccgaacaaag tgttcgaaac
    28921 aaaattaatt attcgtgaga gcgtaaaagt attgacaaag ggctaactcg gcggtatatt
    28981 gcttatgtaa gcatttacaa aggctagtta gtgctttttt tatttttagt aaaccagttt
    29041 actaaagtgg tttacctttc ctaaaaataa tgtataatac cgaatgaaga caaggaggat
    29101 caggcaatgc gaatggtgga tctgattgaa aaaaagaggg atggaaacga gctgtcgaaa
    29161 gaggaaatcg agtacatcgt cacgaactat acgaatggaa agattccaga ttatcaagtc
    29221 agtgcattat tgatggcaat tttttatcaa gacatgacaa atgaagaaat cacgaactta
    29281 acattggcga ttgctaattc tggtgatgtc atcgatttga gttctcttga aggaataaag
    29341 gtagataagc attcgacagg tggcgttggt gacacgacca cattgatttt agccccccta
    29401 gtagctagtg tcggagtgac agtggctaaa atgtctggac gcggtctagg ttacacaggt
    29461 ggtacactag acaagctaga agcaattccc ggatttcaga tcgagctttc ggatgaagaa
    29521 tttgtacgca ttgttaatga aagtaaagta gcggtaattg gtcaatcagg aaacttggca
    29581 ccggcggaca aaaaattgta tgccttgcgt gacgtcacag cgaccgttga ttctcttccg
    29641 ctgattgcca gttcgattat gagtaaaaaa atcgcggcag gagcagatgc aatcgttttg
    29701 gatgtgacca ctggagacgg tgctttcatg aagaacatcg aagatgcaag acgtctggca
    29761 aagaccatga cgagcattgg gaaactggct aaccgagaaa cagtggcggt tatctcagat
    29821 atgtcagaac ctcttggcga agctatcgga aatagtctag aagttgtcga ggcaatcgaa
    29881 acattacaag gaaatggtcc agaagatcta gtagaaatgt gctacgcctt aggaagccaa
    29941 atggttgttc ttgctggcaa agctaagaca accgatgaag caagaacgtt gcttcaagaa
    30001 gctctggaat caggtaaagc gttagcaaaa ttcaaagaaa tgatccaaaa tcaaggggga
    30061 gacccagcga tcgtggaaca tccagaacga attttgactg cacgctacac aatggagctt
    30121 cctgctaaac aaagcggagt tgtgtcaaaa atcgtggcaa atgaattagg aattgctgca
    30181 atgatgctag gtgctgggcg taaaaccaaa gaagaagata ttgatcacgc tgttggattg
    30241 aaactgcata aaaaaattgg tgacactgtg acaaaaggtg agtcactatt gacgatctat
    30301 agtaacgacg aagaaatcac ttctgtcatt gaattattat ataaaaatat tgaaattggt
    30361 gaatcggcaa tgaagccaac gttgattcat gacatcatca cagaataaag gaaaaaagcg
    30421 gactttaccg ttttaaagaa aaggggaaaa gaaatggaac taaaccgaat gatcgaccat
    30481 actattttga aagcagacgc atctaaagaa gctgtgatgc aaattatcga agaagcaaaa
    30541 aaataccatt tttattctgt ctgcatcaat ccagcatggg ttgcgctagc gaaagaacaa
    30601 ttacaaggtg agccagtagc cgtatgtaca gtaatcgggt ttcctctagg agcaaacaca
    30661 cccgagacaa aagcatttga aacaacagat gccatcaata acggtgcaga tgaagtcgat
    30721 atggtcatca atatcggtgc tttgaaatca aaggatgatc aacaagtcca aaaagatatc
    30781 gaagcagttg ttgaagcagc aaaagatcgt gcgcttgtca aagttattat tgaaacatcg
    30841 ttattagata gagaagaaat catccgagct tgcgaaatag caaaagctgc aggcgctgat
    30901 tttgtcaaaa catcaactgg tttctcaaca ggcggagcaa aggtagagga tgtccgtttg
    30961 atgcgtgaaa ctgtaggacc agaaatgggt gtcaaagctt ccggcggtat ccataacgaa
    31021 gaagaagcaa tggcaatgat cgaagctggt gctacaagaa tcggaacaag cgcaggagta
    31081 gcaatcgtat ctggttcaac tggtgaaggc tattaatttt ttcaaaggag aagctcatgg
    31141 cagaactcaa acaagaatgg atcaacacag ctattgaagc gttagataaa gcctatgttc
    31201 cttattccca ttttccggta ggcgcttgtc tcgtaacgga atcaggcaag atttatcaag
    31261 gcatcaacat tgagaatgca tcatttggat taacgaattg tgccgagcgc acagcttttt
    31321 tcaaagcagt atctgaagga gaaaaaacat ttacgcatct agtcgtagcg gggcacaccc
    31381 ccgatcctat ctctccttgt ggtgcatgtc gacaagtaat ggcagaattc tgttcccctg
    31441 atatgccggt tacgctagta ggagacaatg gtgtgacgaa ggcaacgacc gttcgtgcac
    31501 tgctgcctta tgcatttact gaaaaagatc tataactcat gttcattcag tcagctgact
    31561 gttgaaaaat aaaacaatta ttttaggagg ctttacagaa atgaaaaaag caaaattatt
    31621 tggtttaggt gctgtcgcac tagcagcagg gttattttta ggtgcatgcg gcaacaacgg
    31681 ctctactgat tcatccggtg gcaaaagctc atcagacaca acaactgcag cattgatcac
    31741 agacacaggt ggtgtagacg accgttcatt caaccagtca gcttgggaag gactagaaaa
    31801 atgggggaaa gatcaaggac tttcacgagg aaatgatggc ttccaatatt tccaatcttc
    31861 aaatgaatca gattacatcc caaatattga ccaagcattg aatgctggat tcaaaacgat
    31921 ttttggtatt ggttataaac taaaaccagc gatccaagaa caagcaacaa acaatacagg
    31981 tacgaacttt gttattatcg atgatgtcat cgatggatta gataacgttg tatctgcaac
    32041 tttcaaagac aacgaagctt cttatcttgc aggtgttgca gcagcttata cgactgaaac
    32101 aaacgtagtc ggctttatcg gcggtgtaaa aggtgaagta atcgatcgtt ttgatgctgg
    32161 attcaaagcc ggtgttgatg caggtgcgaa agaattagga aaagaaatca aagtattgaa
    32221 tcaatatgct ggtgacttct ctgctccaga taaaggacgt tcaattgctc aaggtatgta
    32281 tgcacaaaac gcagatatca tcttccatgc ttcaggcggt acaggtaacg gtgtattcca
    32341 agaagcaaaa tcattgaacg aatcaggcga caaaaaagtt tgggttatcg gtgttgaccg
    32401 cgaccaatca gacgaaggcg aatacacatt aaacggcgaa aagaaaaact tcacattgac
    32461 atctacactg aaagcagttg gaacagtagt agaagatttg gcacaaaaat cagcggacgg
    32521 taaattccct ggcggcgaac acactgttta tggattgaaa gaagacggtg ttggtctaac
    32581 agaaggacaa ctttctgacg aagcgaaaaa agcagttgat gaagcaaaag aaaaaatcat
    32641 ttcaggtgac gtaaaagttc cagaaactcc tgaagaaaac taaaaccatt tctatagcct
    32701 tgttagacac atgtttgaca aggctatggt ttgattagaa caagaattgt tcatttatcc
    32761 aagctgcctt gtgacagttt ggataaggga acaactccct gaagtaatgt ttgtttcaaa
    32821 agaagaacgc tcactaagcg tgaatcttag tcaatcgttg ccctagatag aaatcgttag
    32881 gatgtgaaaa aaaggtggtt caagaaaata ttgtcataga aatgcagaat attaccaaag
    32941 aatttggaac attcaaggca aatgacaaca tcaatttaca agtaaaggca ggagaaattc
    33001 atgcgttgct tggagaaaac ggtgctggca aatctacatt gatgaacgtg ctttccggat
    33061 tattagagcc gacatcaggg aaaattttga tgcgtgggaa agaagtaaag atcacaagtc
    33121 cgaccaaagc caaccaatta gggattggga tggtccatca gcactttatg cttgttgatg
    33181 cctttactgt aacagaaaac atcgtgttgg gaagcgagcc tagtcgcgca gggatgcttg
    33241 accataaaaa agcacgaaaa gagatccaaa aagtttctga acagtatgga ttgtcagtca
    33301 acccagatgc ttacgttcgt gatatttcag ttggaatgga acaacgggta gaaattttaa
    33361 aaacacttta ccgaggagca gatgtactga tttttgatga gccgacagct gtattgaccc
    33421 ctcaagaaat tgatgaatta atcgtgatca tgaaggaatt agtcaaagaa ggcaagtcga
    33481 tcattttgat tacgcataag ttagatgaaa tcaaagcagt agctgaccgc tgtacagtta
    33541 tccgccgtgg aaaaggaatc ggtacagtca acgttaaaga cgtaacctca caacaattag
    33601 ccgatatgat ggttggaaga acggtttcat tcaaaacgat gaaaaaagaa gcgaagcctc
    33661 aagaagtcgt tttgtctatt gaaaatctag tggtgaaaga aaatcgtgga ttagaagccg
    33721 tgaaaaactt gaacttagag gttcgtgctg gcgaagtact tggtatcgct ggaatcgatg
    33781 gaaacgggca gtcggagttg atccaagctt tgactggttt gcgaaaggca gaaagcggac
    33841 atatcaagct aaaaggggaa gacatcacta ataaaaaacc ccgaaaaatc actgaacatg
    33901 gtgtaggaca cgtgccagaa gaccgtcata aatacgggtt agtcctagat atgacattat
    33961 ctgaaaatat cgcactacaa acctatcatc aaaaacctta cagtaaaaac ggcatgctga
    34021 attattcagt aatgaatgaa catgccagag aattgatcga agaatatgat gttcgaacaa
    34081 cgaatgaact tgttcccgca aaagctttat caggcggaaa tcagcaaaaa gcaattatcg
    34141 ctcgtgaagt cgaccgagat cctgatctgt tgattgttgc aaatccaact cgtggactgg
    34201 atgtaggtgc gatcgaattt attcataaac gtctgatcga acaaagggac aaatacaaag
    34261 cagtgttact gatcagtttc gaattagaag aaattttaaa tgtttcggat cgtattgctg
    34321 ttatccatga aggagaaatt gtcggtatcg ttgatccgaa agaaacatct gaaaatgaat
    34381 taggtctatt gatggcgggc tataccttag aagaagcacg aaaagagtta gaaaaggggg
    34441 ctggcgcaca tgaatgatcg cagcgaaaaa ttccgtaatt tattagtgcc tgtactttca
    34501 gttgttttag gattgatctt aggcgcgata ttgatggctg cttttggttt tcagcccatc
    34561 caaggttatt cttctatgct agatgcagcc cttggttcgc aaagagggat aggtgaaacg
    34621 ttaaggcaag caacgccgtt gatttttaca gcattaggtt tttctgtagc taactcagct
    34681 gggtttttca atattgggct ttctggacaa gcactttgcg ggtggatcgt cagtgtctgg
    34741 gtggcacttg cgtttccaga tctgccaaaa gttgttttgc ttccgttatg cgtgatctta
    34801 ggtgccttag ctggtgcgat ggcagcggct gttccaggtt tacttcgagc attttttgga
    34861 acaagtgaag tgatcgtaac aatcatgatg aactatatct tattatacgt aagcacattt
    34921 gctttacatg aagtgatgcc tgaaagctat cgctcaagtt tggactcttc caatatgatc
    34981 agtcaaaatg cctcactgcg gttaccatgg ttaacacaag cttttggcgg ctctcgcgta
    35041 aactcaggat tatttttagc aatcatcgcg cttattttcg tttggctgct gatgaagaaa
    35101 acgactttag gatttgaaat ccgttctgtt ggattgaatc cttttgcttc tgagtatgca
    35161 ggaatgagta gtaaacgtac gatcgttttg tcgatggtca tttctggcgc tttggcaggg
    35221 cttggcggtg tggttgaagg attaggaacg tatcaaaact tctttgttca aacgacttcg
    35281 ctatctattg gatttgacgg aatggctgtt tccttgcttg gttctggatc agcaatcggt
    35341 attcttttat cagcgatctt gttcagtatt ttgaagatcg gtggacttgg catgcagaca
    35401 ggagcaggtg ttccgtttga gatcgtcaat gtatcgattg ctttgattat cttctttgtc
    35461 gggatcaact tcctgattcg tttcgtcatg gctaaagtct tccaagggaa aaaacaagaa
    35521 gagatcgttg cgacaataga atcgaaacca acgaatcaaa accatgaagg gggcgaacta
    35581 taatgtcgac tatcgaatta attgccttga tccttacttc tacactggtt tattcaacac
    35641 cgctaattct aacgtcacta ggcggaactt tttctgaacg aagcgggatc gtaaacgtag
    35701 ggctagaggg aatcatggtc atgggtgctt ttagttccat cgttttcaac ttgacgatga
    35761 gtccatcact tggttctatg acaccatgga tcgctatttt agtgggtggc gtcgtaggta
    35821 tcctattttc tctgattcac gcagtagcaa cagtcagttt gcgtgctgac catattatca
    35881 gcgggacagt aattaatctg atggcacctg ctttaggtgt tttcttgatc aaagcatggt
    35941 atggtaaagg tcaaactgat aacatcacgc agaatctggg gtatttttct ttcccaggat
    36001 tagcagatat tccggtcatt ggaccaattt tctttaaaaa tacattctta cctgcttatt
    36061 gtgctatttt gattgctgtc ctagcttggg tgatcatctt caagacgaaa ttcggcttgc
    36121 gcctccgttc agttggtgaa aatcctcaag ctgccgacac attaggtatc aatgtatatg
    36181 ctatgcgtta ttcaggcgta ctgatttctg gcttgttagg cggtatgggc ggtgctgttt
    36241 ttgctcagtc gatttccggt aacttttcag ctggtacgat cgttggacaa gggttcatct
    36301 ccatggctgc tatgatcttt ggtaagtgga atcctttagg ggcaatgggt gcctcattgt
    36361 tctttggttt tgctcaaagc ttgagtatca ttggcgcaca attaccagtt atttcttcga
    36421 ttccgccagt attgctgcaa attgctccat atttgctgac aatcattgtg ctggttgttt
    36481 tcttagggaa agcttctggt ccaaaagcaa acgggaagaa ctatatcaaa tcaaaataat
    36541 cttttagcga ataaaaaggg tgggttacgg gaagtgtttt tcgtctcgcc ctttttgttt
    36601 taaaggcaat aaaaataaaa agaaagaagg aataatcatg tttaaacgcg tacatctgat
    36661 cgtcatggat tcagtaggaa ttggagaagc accagatgcc gataagttcg gtgatgttgg
    36721 ttctgataca ttaggacaca ttgcgaaaga agcaggattg aacgttccac atttagagca
    36781 gcttggttta ggaacgatcc gtcctcttga aggtgtggaa tcagtgaaag atcatcaagg
    36841 ctatgcgacg aaattagaag aagtttctgt agggaaagat acgatgacag gccactggga
    36901 aatcatggga ttgaatatca aaactccatt tcgtgtgttt cctaatggat tccctgatga
    36961 tctgatcaaa caaatcgaag aattttctgg ccgtaaagtc gtatgtaaca aaccttatag
    37021 cggaacagct gttattgacg attacggtga acaccaaatg aaaacaggcg atttaattgt
    37081 atatacttct gccgatcctg tccttcagat cgcggcacat gaagaaatca ttcctttaga
    37141 agaattatat cggatttgcc aattcgttcg tgatataaca aaagatgatc cgtatatgat
    37201 tggccgaatc attgcacgtc cgtacgtggg tgaaccagga gacttcacac gaacaagcaa
    37261 tcgccatgat tatgcgttga atccattcgg acacacagtc cttgattctt tgaaagaagc
    37321 aggaaaggac gtgattgctg ttggaaagat caacgatatt ttcaacggac aaggaatcac
    37381 tgaatctgtc cgcacgaaaa gcaatatgga tggcgttgac cagctgctga aagttatgaa
    37441 aaacgatttt tcaggaatca gctttaccaa tttagtagat tttgatgcat tatacggtca
    37501 tcgtcgggat gtagtcggct atgcgcatgc gattgaagaa tttgacttac gaattccaga
    37561 attgcttgaa gcgatggaag aagacgactt gctaatgatt acagccgatc acggaaacga
    37621 tccgacgttt actggtaccg atcatacgcg agaatatgta ccgttattgg tttacagtaa
    37681 aaaaatgaaa gaacaagggg cattgcctca aggatattat tcagatattt cagcaacgat
    37741 tgctgagaac tttagtgttt cttcgactga aaatggcgaa agcttcttga aattattaaa
    37801 ataatctttt taaataggag aaagcaaatg accaagttaa gcgagatgtt acaagaaacg
    37861 acccagttta tccttgataa aggagtaaaa gaaattgatt ttggtttgat tctaggttca
    37921 ggattaggtg aattagcaga tgaaatcgaa gatgctgtaa tgatttctta tgatgagatc
    37981 ccgttctttc ctgtttcgac agtagttggg catgcaggaa agctagttta tgggtctctg
    38041 gcaggcaaga aagtgttagc catgcaaggg agattccact actatgaagg tcattccatg
    38101 caaacagtga cctatccagt acgtgtgatg gccggactag gggcccattc agtcattgtg
    38161 actaatgcat gtggtggtgt caacgaatca tttgtaccag gagatttgat gctgattacc
    38221 gatcatatca attttactgg tgaaaatcct ttgatcggtc cgaatgaaga tgcaatgggc
    38281 cctagatttc cagatatgag tcaagcttat acgcctgact atcaagcaac agcaaaagca
    38341 gcagcagaaa aactaggttt ggatcttaaa gaaggcgtat atatgggcta ttctggacca
    38401 acttatgaaa cgcctgcgga gatccgaatg tctcggacaa taggagccga tgcagtaggg
    38461 atgtcgactg ttccagaagt catcgtagca gctcacagcg gattaaaagt gttaggaatc
    38521 tcttgtatta ccaacttagc agcaggtatg caagcgaatc tgagccatga agaagttgta
    38581 gaaacaactc agagagtcaa acaatctttt aaagcattgg ttaaagaaac attgacatta
    38641 ttgtaatagg aggaacaata aaatgagtgt gcatattgaa gcgaaagaag gcgagatcgc
    38701 cgataagatt ttacttccgg gagatccttt gcgagctaaa tatattgcgg agactttttt
    38761 ggaagatcca gtttgttaca atcaggtacg cggtatgtta ggctttaccg gcaaatataa
    38821 aggagaacgt atttctgttc aaggaacagg aatgggaatg ccatcagcca ccatctatgc
    38881 ccatgaattg atccagtcgt atggtgtaaa gaaattgatt cgagtaggta catgcggtgc
    38941 attgtcaaaa gacgtccatg ttcgtgattt agtactagca caaggtgcag cgaccagttc
    39001 ttcgatgatc gaaaaaaatt tccaagcctt tcattttcct ccaatcagtg atttcaatct
    39061 attactgaaa gcatatgaga tagctaaaga aaagggctat acggttcatg taggaaatgt
    39121 tctttcggaa gattctttct acaaagatga tttgacagag acgttccaat tagctgaact
    39181 tggcgtttta ggagtggaaa tggaagcagc ggctctttat tacttaggcg cgaaatacca
    39241 tgtgcagaca ttaagtttga tgaccgttag cgaccatttg atcaccggtg aagaaacaac
    39301 agctgcagaa cgtcaatcta cgttcaatga aatgatcgaa gtaggattgg aaacagcgat
    39361 agcagaataa gaaggaaatg aaaaagctgc cctgcattaa gtaataagaa catccaagca
    39421 aaaatagctc ctcatgtttt tgacttggct ggacttatta ttgcaaatgt aagcttttga
    39481 acaccgttta ccaagaggtt gtgaatctgc cgtttaactc tgagtcacaa ggaacaattt
    39541 caaaaa
//
LOCUS       DARPZF010000200        20985 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.guided.045, whole genome shotgun sequence.
ACCESSION   DARPZF010000200 DARPZF010000000
VERSION     DARPZF010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.guided.045"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(134..577)
                     /locus_tag="SLE65_003019"
     CDS             complement(134..577)
                     /locus_tag="SLE65_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HEI8450212.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="SLE65_003020"
     CDS             complement(795..2135)
                     /locus_tag="SLE65_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8450213.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="SLE65_003021"
     CDS             2404..3300
                     /locus_tag="SLE65_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HEI8450214.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="SLE65_003022"
     CDS             complement(3450..4391)
                     /locus_tag="SLE65_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEI8450215.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="SLE65_003023"
     CDS             4517..5638
                     /locus_tag="SLE65_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEI8450216.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="SLE65_003024"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="SLE65_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HEI8450217.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7426..7992
                     /locus_tag="SLE65_003025"
     CDS             7426..7992
                     /locus_tag="SLE65_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEI8450218.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="SLE65_003026"
     CDS             8203..9264
                     /locus_tag="SLE65_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEI8450219.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9267..10163
                     /gene="murQ"
                     /locus_tag="SLE65_003027"
     CDS             9267..10163
                     /gene="murQ"
                     /locus_tag="SLE65_003027"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HEI8450220.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10177..12159
                     /locus_tag="SLE65_003028"
     CDS             10177..12159
                     /locus_tag="SLE65_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEI8450221.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="SLE65_003029"
     CDS             complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="SLE65_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEI8450222.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            12881..14305
                     /locus_tag="SLE65_003030"
     CDS             12881..14305
                     /locus_tag="SLE65_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8450223.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14486..15259)
                     /locus_tag="SLE65_003031"
     CDS             complement(14486..15259)
                     /locus_tag="SLE65_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEI8450224.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(15256..16161)
                     /locus_tag="SLE65_003032"
     CDS             complement(15256..16161)
                     /locus_tag="SLE65_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8450225.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(16315..16635)
                     /locus_tag="SLE65_003033"
     CDS             complement(16315..16635)
                     /locus_tag="SLE65_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HEI8450226.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            17109..17795
                     /locus_tag="SLE65_003034"
     CDS             17109..17795
                     /locus_tag="SLE65_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEI8450227.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            17797..18741
                     /locus_tag="SLE65_003035"
     CDS             17797..18741
                     /locus_tag="SLE65_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEI8450228.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            18940..19584
                     /gene="pcp"
                     /locus_tag="SLE65_003036"
     CDS             18940..19584
                     /gene="pcp"
                     /locus_tag="SLE65_003036"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEI8450229.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            19663..20940
                     /locus_tag="SLE65_003037"
     CDS             19663..20940
                     /locus_tag="SLE65_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450230.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCHYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         6778 a         3784 c         4362 g         6061 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     9361 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     9421 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     9481 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     9541 gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag
     9601 ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt
     9661 tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg
     9721 gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac
     9781 aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt
     9841 tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt
     9901 ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac
     9961 caacaaatga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg
    10021 attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg
    10081 tcatgatttt gacaaatagt gataaagagg aagctcaagc aaaattagct gaagcaaacg
    10141 gatttgtaaa agggacctta tgagggggaa aagaccatgg caaaaaacga actgactttg
    10201 gaagaactgg caaaacaaat ttataaaggg gcaggcggca tgggcaatgt agaaagcatt
    10261 gtccactgca tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt aaatgtctct
    10321 gaattaaaag cgattccagg agtgcttggt gtagtagaag atgaacagct tcaagtcatc
    10381 atcggacctg ggaaagtgaa caaagtagca cagcaaatgg ttgatttggc aggcgtgaaa
    10441 ttaggagaaa aactttcttc tgtaagtaca gctacagcaa attcatcagc atctggaaaa
    10501 gaccgtgtaa acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa acaaaaacca
    10561 tctaaaatca aatcggtatt aaaagacatt tctaatatct ttgtgccaat gattcctgca
    10621 tttgtcggta ctgggatcgt ggcagggatt gccgcagttt tagcaaactt agtcacagcc
    10681 ggaacacttg atgcagcaac atggcaacaa tatatcgatg tgatgaacat cttgaaaaac
    10741 gggatgttta gctacctagt tatctataca ggtatcaatg ctgcacaagt ttttggtgca
    10801 acaccaactc ttggtggagt tatcggggcc gttgtgatgc tgacagggat gaatccggaa
    10861 gcaccactga aaaacttatt tactggtgaa gctcttgcag ctggacaagg tgggatccta
    10921 ggtgtcatct tcgctgtttg gctattgtca atcgttgaga aaaaactgca taaagtagta
    10981 cctgatgcgg tagatatcat cgttacacca actctttcgt tgattgccat cggtctgatt
    11041 gaaattttct tcatcatgcc tttagcaggt ttcatttctg atggcatggt cggtgggatc
    11101 aactgggtac ttggcgttgg tggagcattt gccggcttcg ttctaggcac attattcttg
    11161 ccgatggtta tgttcggact gcatcaaatt ttgactccaa tccatgtgca aatgattgat
    11221 gaaactggtc gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg acaagtgggt
    11281 gcagcattgg cattatggat tcgctgcaaa aaagataaag aattaacaga aatgatcaaa
    11341 ggagctttac cagtcgggat cctaggaatc ggcgaaccat tgatttacgg agtaacatta
    11401 cctctaggac gcccatttat tactgcttgt atcggtggag gtatcggcgg ggcagtgatc
    11461 ggaatgatcg gaaatgtcgg ggctatcgct attggacctt caggagccgc tttgatccca
    11521 ttgatctctg acggtaaatg gttaggctac atccttggat tattggcagc ttatgctggt
    11581 ggcttcgttg ctacattctt cttcggtatt cctaaagacc gtttagaaaa agaagaatta
    11641 gcgactgaaa cagccacagt aaatgaagtg cctgaaaaag tagtacctca aacttcagct
    11701 gaaagtgtga ctatcctctc atcagttgct gacggaacag ttgtttcttt agataaagca
    11761 agtgatccag tttttgcaca aaagatgatg ggtgaaggct actttgtaga accagaaaac
    11821 ggacatatct attctccagt tactggggta gtcagctctg tcttcccaac gaaacacgct
    11881 attgggatca caacgccaaa tggtttagaa atcttgcttc atatgggaat caacacagtt
    11941 gacttaggcg gtacgccatt tgatgtgaaa gtaacagaag ggcagcaagt gacacctgat
    12001 acgcttgtag cagaagctga cttagaagcg atcaaagcag caggcaaaga aacatccatg
    12061 atcgtcttgg taaccaatat ggatcgtgta aaaaactttg tcttggaaaa aacaggtaaa
    12121 gcaaaagcaa aagcacctgt gatggatgtc aaagcttaat atgatagaaa caatagaaac
    12181 gaaagaagaa actgaaatct atttttcagc ttcttctttt ttattattta ttgttttctg
    12241 ctaaaatctg ataaattcgt gtcacatcag atggtgttcc ccgtaattca taatctgcca
    12301 agaaaggaaa gccaaatgtt tgtgcatatt gtttggctgt tagacaatac tgattattga
    12361 agtttttatt tccgctaccg actacaccaa gacaaagttt atgattgtct tcatgttcca
    12421 gatattcacg catcgtttcg gtcaagattt ctgtatcacc gttatctaaa ccatttccgc
    12481 cgtctaaata agtaggaacg aaagtaaaaa atggttctgt ttctttcgta aaatcactat
    12541 tttcatggat ttcttttaaa gtaacttcag gattgacagg atcttctgca tgcatttttt
    12601 cagcatattc tgctagatgt ttggcaaagg cacgcgtatt tcctgaaatc gatatatata
    12661 aaatgttcat ggatcatcct ccaattcttt ccttttagta tagcatcttt tttaagtttt
    12721 ttggtggtgt aatttggaaa gggactaggc gctttgcttg tataatgaga aaaaagccgg
    12781 tagaattata tttctattaa agtttttatt aattaagtaa aaataaaaaa ggtttgttat
    12841 actttttgat aaaagcggtt ttattttgga ggatgcttac atggatacag agcaacagaa
    12901 aaaaggaatt ggtttaattc cacttgctgc cttagtaatt ggttcagcga ttggaggtgg
    12961 cgtatttggt attatgacgg acatctccgg atcggctggc ggcccagcta ttttcagttg
    13021 ggtactcgta ggaacagcaa tgttgatgct ctccttgtcg atcaataata tcaataaaaa
    13081 acgtccagat ttaaaaggcg ggatctttag ttacgcagaa gaaggttttg gccgtttcgc
    13141 tggttttatc agcggttggg gttactggct cacatgctgg ttaggcaacg tagcttttgc
    13201 aacattgttg atgagcgcat taggatattt cttcccagta tttgaaggtg ggcaaaatct
    13261 ggcatcgatc gtgatgagta cagtcttttt atggggatat gcatggctag tgaatcgggg
    13321 agtcgaaaat gctagtttcg tcaatgctat cgtcacattc tgtaaattag tgccattatt
    13381 tttatttatt gtagtagcta tcagcacgtt ttcgatccaa caattcattg ataacttttc
    13441 tagcgacatt atattgaatg cgaatggaca gccgatcccg ttttccagtc aagtattgag
    13501 ttgcatcatg gtgatgcttt gggtatttgt tggtattgaa ggagcctctg tcgtaggttc
    13561 acgagcaaaa aaacaatcag atgttgggaa agcaacgatt ctagggatat tcggcttgat
    13621 tattatttac gtcttggttt ccatgcttcc atatgggaca atgacgatga atcagctgca
    13681 aacgatcaag gcgcagcctg ctatgggcta tgtgtttgaa atgatggttg gtaaatgggg
    13741 agcagtcgtg atcaacggcg gtttgatcat ttctttagtt ggtgtttggc tctcatggac
    13801 gatcttaccg attgaaacaa tgggaaacat ggctgaagac ggacttttgc ctaaagcatg
    13861 gggaaaactc aacaaaaatg gggcaccaac ttatgctatc gtattgacga cgttatgtac
    13921 gaatgtcttt ttactttcat tattattcac tgacagtgct tataactttg cttacacact
    13981 tggtacagca gctattttct tcacgtggct tttcttagga ttgtaccaaa tgaaactttc
    14041 ttatcagcgg aaagaatggg tccaattttt agtagggctt ttagcaagtg cctttcaagt
    14101 atgggctatg ctagtcgtag cctttaatga agtaatgctt gttcttgttc ttttcttgcc
    14161 aggcatttat ttttacctca aagcacgtaa ggagcaaaac gagcctgtac aacatatcca
    14221 cttagataag attttactta taggtgtgac gatggtcgga gtgattgcaa tggttttatt
    14281 tgccactggg atgcttcacg tatagaagta taaaagaagt ataaagagag gttgtgagcc
    14341 tgtcgtttat tcaaaaacat actaggaaag gagctgtgac acaaatgttg tcacagctcc
    14401 tttttcagaa taaacggtgt ttaagagaca gccaatcggc aataaggctg aacgtctctt
    14461 tcacagcctc ttttttgatg agtcatcata cattttttcg cttaaatacg agatatccta
    14521 atgctaagaa caaaacgatg taagctaaat taccgaatag catttgatta gtagaaagat
    14581 gagtcaattg cttcatgatc tcttcgtttc caatttggtt ttgcagattc aacatactga
    14641 tcggattcca tttgatccac tcccattttt ggatgagtgc aataaggata ccagatatga
    14701 ttgacgaagc aaaataaaag acgattcctg ctgagatgga tgcgccggaa ctattgataa
    14761 agcaagcaat catcaacact aaacttaaaa tcagccataa accgatataa ctacccaaag
    14821 tataagtgaa caagctttgg atcagtgttt gaccagtaga aaccttctcc gtgaaggaaa
    14881 tcgaagggaa aagaatcagt ttcatcaaca cagtgacaat aatagctaaa aggtataaat
    14941 aaacagaata aataactaat gtgatccatt tgcttactaa tatttctcct cgagaatact
    15001 ttcgataaag gagatttttc aatgtaccat attgtgcttc catcgaaatg atcgtgcttg
    15061 cagctgcaat catgataaag acaatccaag atgtggcact aaaaagctga gcagtcattt
    15121 caactggatc aatgatcgtc gtgtattttt tggctagaag tgctgttcct atgagcaaaa
    15181 caactaatag aacagataaa acagcagttg actttttctt gatcaattta aataattctt
    15241 gttttacaag caatgtcatt tttcttcttc cccctttact gaatccagaa tttccaatag
    15301 agaagattcc aaatcattcg tcagatgctg gacgtctgtc acatggatat tttgtgcaga
    15361 caatagctgg atcacggttc ctaataattc ttcgttttct tttaaaagct tgattttatc
    15421 aggatcttcc aaagtatatc cagcttctgt caagatcgtt cgagcagcta gatcatttgt
    15481 tgtagagata acgatgaaat cttgcgctgt ttggttcaat tcagccattg tacattgttt
    15541 gatgatcttt ccttgattga tcaggatcag ctcatcgacc attttttcaa gctcgctgag
    15601 taagtgactg gagatcaaga aagaggtgcc ctgagtagcc aagtcggtaa tgatttttcg
    15661 cacatctctt gttgcttgtg gatccaaacc gttcatcggc tcatctaaaa taacgataga
    15721 cggatggttc agtaaggcaa gagcaattcc caatttttgt ttcattccca acgagtagga
    15781 tttcgctttt ttgtgaatgt acttttccat cttgagctga ttcacgatag tgtcgatagc
    15841 agatacatcg ttggtttcag agaataactt cagatgatca tagcctgtta agaatggata
    15901 gatacccggg tattcgatca atgctcctac ttgttccaac cctttatgac tagagggaga
    15961 aatctcattt tcaccaatac agattgttcc atctgagtaa tggatcagtc ctaaaatagc
    16021 tttcatgatc gttgtttttc cagcgccatt aggacctact aatccaacga ttttgccagg
    16081 ggataagcta aaactgacat cgctgagggc ttgtttgtga ccaaagttct tggataattc
    16141 ttggaccgaa agacttttca aaaatattca ctccttttct atagatagta caagcataca
    16201 cctgatgagt ggagaagtcg ctaggtcatt ggacttattt cttatttttt cataaaaaaa
    16261 ttgaatatta aataaaaagg cttatttttt ctgatcagta cttattccaa gtgtctagtg
    16321 gccgctagta atcttgatgc caatgatact gatgagtagc atccccacaa agaaccaagt
    16381 ggaaagattc agcttatcat gaaacaagac cacaccaatt atgaccgaac caactgcgcc
    16441 aatccctgtc cagataggat aagagagact catcggcaaa cttttgattg cctttgacaa
    16501 aaagtaaaaa ctagcaatca tgccaatcac tgtgtaaaaa gaataattga ttttagaaaa
    16561 accatcactc catttcatca tcgttgacca gaatacttcc aaaattcctg ctatgattaa
    16621 ttccatccat gccatactta cattcctcct taactataaa aaaatacaca aaaagaggaa
    16681 aatcatccct tcaaagacct aatggaatga tcatcctctt tatcctaccc ggtggcagat
    16741 tgtatatctt tttctgtagt atagcacacc tatccagata tcggcaatct catacttttt
    16801 agtaaagtgt accaagcact gacggatata tcgttagcgg aaaagaagat gaatgctttg
    16861 caatttcata gaaagaagtt gttatttatt aatcatttaa aaaaaacagt aactagacct
    16921 tatttctata tattatcggg caataaatta aaaaaagctt taccttacaa taagtaagat
    16981 aatttttgtg ataaaaaaat aacgaaaaat atttaaaaat agtgtctatt tcgtgagaaa
    17041 acaactatat tttttatgtg ttttgcttta taattaaaaa aatattgtca ttttatggag
    17101 gaaaatatat ggaaaattat cttagccttt taggcgtctt gattgttatt ctcgggtttg
    17161 catttaaatt agactcgata ttgatcgtaa tggttgcttt agttgttaca gctttgactg
    17221 gcggtcttgg cattcaagga atgttagaac ttttaggtac aagttttgta aacaatcgcg
    17281 ggatggcgat ttttatcatc attatgttgg caacaggaac gcttgaaaga aatggtctga
    17341 aagaatcagc ggcttccttg atcaagcgat tcaagaaagt atctgctggt atgattgtag
    17401 atatttatgg gatctttcga atgatctttg cggcttttaa cgtgagtttt ggtggagttg
    17461 ctggatttgt tcgtccaatc attttaccga tggcattggg gaccatcgaa tcaaaagggt
    17521 tagaagtcca tcctaagcat gaagaagaac taaaaggtat ggcttcagct atggaaaatg
    17581 tctgctggtt ctttggccaa gtactattca tcggaggagc aggggcgttg ctagtccaat
    17641 caacactgaa agatctagga tatgacgtaa cattgggaca gcttgcttta gtggaagttc
    17701 cagtggctat cacggcttta gttgtggcaa gtgtctactt ctatcttaaa gaaaagaaat
    17761 tagcgaagaa atattatcca ggaaaggggc aataagatgg acttttttac aaatcctgat
    17821 attttattag gcgataaatt actggagatc ctttatatcg tgatgggact cgtattgatt
    17881 tacactggag taagaaattt aacagataaa accaatcctc atcgttatgg gtcagccttt
    17941 ttctggacgg tcttaggggt agttattgca ggaggaagat ggcttccggc aatcgtgaac
    18001 ggtggcttga tctttgcgat gaccatacca gcaattgcta agaaagtcag caaaggagaa
    18061 agccggcttc catcaaaaga atatatggaa aaaatgtcag acaaactagg aatgaaaatt
    18121 tttattccag ctttgagtat cggtgtcttt gcgatcttgt ttgctctatt taccaattta
    18181 ggtgctttag tcggcgtggg cgtcggtgtt tttgcagcca tgctaatctt gatgttcttt
    18241 tctcgagata atcgaccaag tacattttta gatgatgcag cagatatgct gggcacagta
    18301 gggccgttaa gcatgttgcc aatgctttta gcttctctag gtgcggtatt tacaagcgct
    18361 ggagttggga cagtgatttc caatgcagta ggtacgatcg ttccagaagg aaatgtgaac
    18421 atcggcatca tcatttacgc tcttggcatg gtgatattta cggtaatcat ggggaatgca
    18481 tttgcggcca tcaccgtgat gacggttggg atcggtgcac cattcgtatt tagtcatgga
    18541 gcgaatccag cgttaatagg aatggttgca ttgacttgcg gtttttgtgg gaccctgctg
    18601 acaccgatgg ctgctaactt caatatcgtg cctgtagcga tgctggagat gaaagacaaa
    18661 tacggagtga tcaaaaacca gttgtttatt gcgttattta tgctagtttt ccaaattgct
    18721 tatatgattc tatttaaata atagaagaga ggggttgtga cagaataatt gtcgcaacct
    18781 cttctaacat tgtagtggaa cactattttt ttataagaat atattaagtt tgatctgtta
    18841 tgttatttaa actattgttt cctttattta cgctgttcaa ggaaaatggt atgataaaag
    18901 ataaccatat gttaaatcaa tcggacggag gaacaacaga tgaaagtact agtaacaggt
    18961 tttgatccat ttggtgggga caaagtgaat ccagcctatg aagcagtaaa aaaaatgcca
    19021 gatgaaatca gcggtgctga aatcatcaaa gtggaagtac cgaccgtatt cgaaaaaagc
    19081 agtcaagtag tcaaagaagc catccaacag caccaaccag atgtcgtgat ctgtgtcgga
    19141 caagcaggtg ggcggtcagc agtctcgttc gaacgtgtcg caatcaatct agcagaagca
    19201 agaatccctg ataatgaagg aaatcagcca ttcgatacgg ctttagaaga aaacggtcca
    19261 gccgcttact ttacctcatt gccaatcaaa gcaatgacaa aaaatgtaca agatcatggt
    19321 ctaccagcgt acatctctta tacagcagga acatttgtct gcaatgatat catgtatcgt
    19381 ttgcttcatt tgatcgaaac acaattcccg gcaattcgag gtgggttcat ccacgtgcca
    19441 ttctcacccg atcaagtgat cgatcgtcca gtgggtacgc cttctatgtc tttagaagac
    19501 attgcttctt ctttgactta tgcagttgaa gcagcagtag aaaataaaga agatatttcc
    19561 ggaaatgccg gaacaactca ctaatttagc aagaaacact ggctggttgc taacgttatg
    19621 ttagtagcca gctttttgta attagaaagg aaagaaacag ccgtggaaga atggcaatcc
    19681 gtctttgaag aatggtttcc aaaagaaatc agcaaaagct atcccatcaa aatttctaaa
    19741 caatacacaa gcagtcaacg ttgggagatc tatgcaaaat taacgaaaaa acagcgggaa
    19801 ctagtcgata agcaccgccg atatctaatc agctctcgtt ttatggaaga acattattta
    19861 gctgcaacag attgggtgtt ttctgacttc aagatcaatc cgttttttcg aacaaaacga
    19921 agccagcaaa aattgtattg tgagtgtggt agagaattaa aagtgcaata catcgttaaa
    19981 tcgccaaaaa ccggaaagat cctaaaacta ggcatcaacc actttgccga tcacctgcat
    20041 gtctctccga cagtggcagc ttcgatccat cagggaatga caaaagttga tctggcctta
    20101 gacgaattat tatggcttaa gcagaagaat atcgattttc ctgaaggact atggcaaaaa
    20161 tactgttttg tcttgtacca aaatcgtcgg atgaaacagc catatttacc ggatataaaa
    20221 ttagctcagc ggctcgcaga atttcgccaa gtagaaatgc cgatttacat agcggattat
    20281 caagcattgg aaaatgaaat caagaaaata agtgaacaca tcaatgggca gtcaaaaaag
    20341 cgacagataa aaaaagaact atttgacgac tttgcagaag aattagtaaa ggatgtagaa
    20401 gaattcttga tcaactatcg cgcattttta cgtaaagatt ggcaatccat cgtatatgaa
    20461 gaagtgccag tacatcctaa tgcttatttt gaaacattta tttccgtgtt gagaaagaca
    20521 aaacgtcaac gaacaccaga agtcactgct cagatggaat attttgcgaa aaaccaacga
    20581 ttcatccaac caaaaatcta tctatttatt tggaagcaat attgtcacta tggttttaca
    20641 gaagggttct tcgacagcat tcctcggata gtcagaaatg gttttttaaa agtattgcgt
    20701 aaagaacgag aagctataca atctgctgat aagaaagacc gtacagtctc aaaagaaaaa
    20761 tggcaactag tagtgaaaga tatccaatct ggaaatgtgc aagagacaat cgacaaatgg
    20821 aaaggaaaac attatcgttt tactgaagct cagaaacaag cgttggaata ttatcagaag
    20881 ttagaagaat cactgcgttt caatgatgag gcaagaaagt atctgaagga attactataa
    20941 aaaatagagg ctgggacaga agcgtttaac tccaagaaat aagaa
//
LOCUS       DARPZF010000201        16775 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.guided.055, whole genome shotgun sequence.
ACCESSION   DARPZF010000201 DARPZF010000000
VERSION     DARPZF010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16775
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.guided.055"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            366..1229
                     /locus_tag="SLE65_003038"
     CDS             366..1229
                     /locus_tag="SLE65_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEI8450231.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            1329..1811
                     /locus_tag="SLE65_003039"
     CDS             1329..1811
                     /locus_tag="SLE65_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HEI8450232.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(2074..2541)
                     /locus_tag="SLE65_003040"
     CDS             complement(2074..2541)
                     /locus_tag="SLE65_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEI8450233.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            2664..3515
                     /locus_tag="SLE65_003041"
     CDS             2664..3515
                     /locus_tag="SLE65_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8450234.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(3766..5724)
                     /locus_tag="SLE65_003042"
     CDS             complement(3766..5724)
                     /locus_tag="SLE65_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEI8450235.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(5721..6593)
                     /locus_tag="SLE65_003043"
     CDS             complement(5721..6593)
                     /locus_tag="SLE65_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEI8450236.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(6935..7807)
                     /locus_tag="SLE65_003044"
     CDS             complement(6935..7807)
                     /locus_tag="SLE65_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEI8450237.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            7935..8504
                     /locus_tag="SLE65_003045"
     CDS             7935..8504
                     /locus_tag="SLE65_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HEI8450238.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            8571..9308
                     /locus_tag="SLE65_003046"
     CDS             8571..9308
                     /locus_tag="SLE65_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8450239.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            9539..10807
                     /locus_tag="SLE65_003047"
     CDS             9539..10807
                     /locus_tag="SLE65_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEI8450240.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            11294..11758
                     /locus_tag="SLE65_003048"
     CDS             11294..11758
                     /locus_tag="SLE65_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEI8450241.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            11742..12371
                     /locus_tag="SLE65_003049"
     CDS             11742..12371
                     /locus_tag="SLE65_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEI8450242.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            12725..14203
                     /gene="msr(C)"
                     /locus_tag="SLE65_003050"
     CDS             12725..14203
                     /gene="msr(C)"
                     /locus_tag="SLE65_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HEI8450243.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            14250..14696
                     /locus_tag="SLE65_003051"
     CDS             14250..14696
                     /locus_tag="SLE65_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HEI8450244.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(14895..15410)
                     /locus_tag="SLE65_003052"
     CDS             complement(14895..15410)
                     /locus_tag="SLE65_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEI8450245.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            15527..16729
                     /locus_tag="SLE65_003053"
     CDS             15527..16729
                     /locus_tag="SLE65_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8450246.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         5300 a         2989 c         3482 g         5004 t
ORIGIN      
        1 gatgaggttg aacttttaca caagattgtg gacttgactg caaagaaaaa tccaagcagc
       61 gttctgatca gcagtttgaa caacaatttg ctttgtacag taggtagtaa gcggattaac
      121 taagggaata aaagatattt ttaccgcttt gtttacttag aatctgtctt ccccaaaatt
      181 tatttttcta aaggtaaaac atagataggc agataatacc aattatccgt tacgaaacgc
      241 tgcttgagaa ttttctttag atccatacaa cattttctac atctgactaa attggttcct
      301 gattcatcaa gtaattgact ttctttgata atatgataaa aaggcaatca aggaggaaga
      361 taaatatgct taaagatctg aaccaattga tcgattacat cgaagaacat ttgacagaag
      421 gactttccta taaaataata gccgaaaata caggaatctc tgaatatcaa ttaaaacgca
      481 tctttacgtt tattgcaggg atgtcgctaa tggactatat caaaaaccgt agattggctt
      541 tggctaatcg cgatcttcta gatggatcaa gagtgacaga aacggcgttt agatatggat
      601 atgaaacagt cgaaggtttt tcaagagctt ttcgtgattg gtcaggatat ctgccttcag
      661 aaatcagcag atacggcata caaaaatctt ttccacgctt gacatttttt attgatgtca
      721 gaggaggaaa atcgatggaa tttcgtatcg aaaagaaaga acagttttat gtggcaggtg
      781 tggcgaaaaa agttcctgtc aaatttgaag gagtcaatca agaaatacaa aagttagcgc
      841 agacgatcac ggagactcaa agggaagaga tgcataagtt aggagattta tatccaaatc
      901 aagtaatcaa cgtttcttat ggatttgatg gagaccgctt ggaagaaaag ggcagtttga
      961 tgcacatgat tggctttgct acgacaaaag aaaatccgta cgctgattta gaaatgcttg
     1021 ctatagaaga acacacttgg gccatttttc ctaataaagg gccatttccc caaactttac
     1081 aagatacttg ggggaaaatc tatgcagaat ggcttccttc ttcagattat gggttagtcg
     1141 aagctcccga gatctctttt acaaaatggg gagaggattt cagtaatgtt tacagtgaga
     1201 tttggattgc agtgaaagca aaaaaatagt taaaaaataa aaatatccct agaaaaaaga
     1261 gcgtaatcgt gtcatttccc tttaatttta tgtaagatga acttaatata atagaaaggg
     1321 tgggagaaat ggcaaagtat aggatcgaag aaaaaccaga ttttacggtg acgggtattg
     1381 gtgtggaatt gaagagtagc aatacggatt ttgtcggttt ggctgcagag aaacaagcat
     1441 ttgagcaaaa agttatcggt aatggaacaa tagatgcatt gaaacaagct gctgaaaatc
     1501 attatttctt tacagtcaac gaaccctata acgggaaaat gatgtactat gtcggtgttc
     1561 aaacgagtca ggatgttcca aacactacgc gaatcatccc attcccaaaa ggaacgtatc
     1621 ttgttgtaag cgctttagca gaatcgcctg aagaattaag aaatgatttg acgaatacgg
     1681 cctttgggca tgttttaaga gaagtagaag attacgccta tgttgggggt ccaaatgctg
     1741 tagtcgaaat gggagttacc aacgggaaat atatgggaga aatctggata ccggtagtca
     1801 ataaaccatg ataatataga ggtcgtgaaa gtagcgcttt gacctgagca ttagagagga
     1861 aaaatgggaa atagctttcc atattttgca tttttcagaa ctaatgccga gggtcagcta
     1921 cttgaacacc gtttatcaag acgtcatgac ttcagcgctt tgacctgagc attagagagg
     1981 aaaaaggggc atgacaaggc ttttgtcccc cggagaataa aagaatttat gtagacgatt
     2041 ccgatcagaa aaatgcaggc acagtagaga gaattataaa aatctctcta cgaggcctgt
     2101 gttttctggt cttttttctt tttccaaaac ggctatttta tgtatcagac tatcaagtgt
     2161 gatcttagcc atttcttctt ctgccttttt ctgcagccga gcgtagcttt cttctaaagc
     2221 ttcttggata ttcgcaccaa cgacgcaatt tggatttgtt tttggatcga cttggataag
     2281 ctgtgtatta ccttcgatgc tgcgatagac atctagtaaa gaaatctgat ctggactttt
     2341 ggcaagggaa ggctgcggtt ttccggtttt tgtaaagatc aaaccggatt ttttgagctg
     2401 actcatgatt ttacgtacat ttgctgcatt tgtttcgata ctactggcaa tcatctcact
     2461 agaaagtgat cgggtatctt gaaacatttc aatataggca agtacatgga ttgcatcact
     2521 aaattgcaga gaatacttca tcagttgtca tcctttcatt ttttttgctt gacttatctt
     2581 accacactct ttatgataaa ggtgtaattt ataaatgtac agctgtaaat cttaacaaat
     2641 aaaaagaata gggagtggca aatatgcatt atttagtaac aggagcaact ggaggttttg
     2701 gtggttatgc gctggaattc ttaaaaaaga tggttccaca aaatgaaatc tatgtactag
     2761 tacgtagtga agaaaaagga gaagcactga aagaagctgg atttaatata cgtattggtg
     2821 attatgatga tttagactca atgaaagaag cgttgaaagg aatagatcga ttgctttttg
     2881 tctctggcgt tccaggaaat cgtcaagccg aacataagaa tgtagtgaag gcagcacaag
     2941 cagctggggt atcttatatc gcttatacaa gttttgcaga tgccgatcac tcgatcagtg
     3001 tattagcgcc agatcaccaa ttcactgaaa aaatgattaa ggattcaggt atttcccata
     3061 catttttacg gaataattgg tatgtagaga atgaattacc tatcattggg caggctttaa
     3121 aaactggtca attcgtttat gctgcaggaa atggaaaaac aggttgggca ttgaaacgtg
     3181 aatatgcaga agctgcagca aaagtactag tagaaagtga ctctccagaa atcttagaat
     3241 tatccggcaa tctaactgac tatgaagaat tagccaaggc attagagcgt gcgacaggta
     3301 aagagttaga aattattgaa gcaagtgatg cagcgtttgt cgaaaatcta aaagaagccg
     3361 gattccctca agaagcagct gacatgtttt tagcgatcca acatgatatt aaaaaggatc
     3421 agttagctat ttcctctgat gatttagaaa aagtattggg aaaaccatta acttctcttg
     3481 aagcagcatt aaaagaaata ttggatcagg aataatgtat aaagaggttg tgaaaaagcc
     3541 gattagtttt gagtatgaag aaaaattttg tgaaaaagct gttctgcatc aagtaataag
     3601 aagagtcaaa taaaaaatag ctcttcatat gtttcgttta gctggactta ttaccgcgga
     3661 gttggcagga gaacgccgtt tttattcgga aaaaggagct gagacaagat ttttgtctca
     3721 gctcctgttt gtttatcgat aaaaaagtct ggggaagacg atggctcagg ctttgttgga
     3781 aacagagccg attttatcat ttgcttttac atcacgtgcg ggttcgattt ctaagctttg
     3841 gactttgtcg ccatttgtga atacaacgac catatccgtg tttttgcctg cagattgaat
     3901 agcggcaaga tcaactaaag caatcaattg acctcttgcg actttttgac cttcttctac
     3961 atataaagtg aatggttcgc cttttaagtc aacagtgttg atgcccatat gaagcaagac
     4021 ttcgatacca gcatctgttt ggattccgac agcatgtttc gttgggaaaa tgtttgtgat
     4081 cgtaccagcg attggagaga agatttctcc attttctggt aatacagcat agccgtcacc
     4141 catcattttt tccgcgaata catcatctga aacttcagtg attggaatca gtttcccatt
     4201 tgcgatagcg taaatatctt gttcgatcgt ttcaccggca aatgtttctg ttttaaccac
     4261 ggtgtttgtt tgtgcaggtc gtgctgcagc accaccatgt agttttgcca tctcatctgc
     4321 aacgaattgt acttctgtac ctacgatgac ttgcgcattt tttccgtcga tgatcttcat
     4381 accaggtacg ccagtggctt tgattttatt ttgatcgatc aggcctgtat ctttgacttg
     4441 caaacgaagg cgtgtagtac agttatcgat cgaagttaca ttgtcggctc cgcctaatgc
     4501 agcgtagatt ttgcttgctt gtgccgcata tttattgtct gaattagtcg ttgcagtatc
     4561 gtcatctgaa agatctgctt cctcgcggcc aggagtcatc agatggaatt ttttgatagc
     4621 aaagttaaag ccaaagtagt aaatcactgc tgttactaat ccttggacga tcaacatcaa
     4681 tggctgattc gcaatcggat ttttcaaaga taggaagtaa tcgacaaatc cggcactaaa
     4741 ggcaaatcct gctgtccaat ggaagaatgc actcactgct aaagaaatcc cagtgaaaat
     4801 tgcatgcaag acatataatg gccaagcaac gaacataaat gaaaattcaa gtggttctgt
     4861 cacaccagta aagaatgaag caaaagctgc tgctagcatc aaggaagctg tttttgcttt
     4921 gttttctgga cgtgcatttc tgtaaatagc atatgctcct gctggaagcc cgaacatcat
     4981 gattgggaaa aatccagctt gatacattcc tgttacgcct tttgttcctt cagaagccaa
     5041 aaatttacca atatcattga ttcctgctac gtcaaaccag aacacggagt tcattgcttg
     5101 atgcaatcct gtagggatca gtaaacggtt gaagaagcca taaagacctg caccacccca
     5161 gcctaaactc aaaatgaatt tagcaaaaga aactaaagca gagtaaaccg gaggccatac
     5221 gagcagtagc actgcactga tcagcaacat gacaaaggca gccaagattg gcactagacg
     5281 cttgccgcta aagaaagata aagccatcgg taattttgct tcgtggaaac gattataaag
     5341 agctgccgca atcaatccgg caataatacc aataaatacg ttactgatct gagcaaaaga
     5401 tggatcaact gattctggtt tgatattcaa taaagtagct actgaatcag tttttaaaac
     5461 atttactgga acttcaaatg cgaccaaacc tgccaaggca gcagcacctg atttgtccac
     5521 tgacatccct agtgctaacc caacggcaaa cagcaaaggt aattgaccta aaactgcgtt
     5581 accgccagct tgtaaaaaat gagcgacaat gtcgttacta taagatgccc accagtttcc
     5641 gatccctact agtaaagcag cagcaggtaa gaccgcaact ggaagttgaa gggaacgtcc
     5701 cattcgttgt agatatgctt tcaatttttt tcctcctcat gattgttaac atttgtttgt
     5761 acgattgcgc ttcttaaacg ctcgatatgg atggccaagt aacccagttc ttctttcgtg
     5821 atcgcgagct ggtattcttt ggtcagcaac acacggattt ttttagaaat cttatagctt
     5881 tctgggtatt ttcgtttgac catttctacg atttccgtgt ctaaaacagc atattgttgc
     5941 gcatgggttc gttgtagaag tagtcgtaaa tgattcacca gtcttgaata attcagtgaa
     6001 aatggttctg aatggatatc tgtttccaat tctgattcca ctaaatggat gatgtcagat
     6061 acaatcgtca cttcacggat actgcgatgg ttattgttcc gaccgcttcg tccgctgtga
     6121 atatggattg cgatatatcc tgcttcgtca taagtatatg gaatcccaag ctcttttgtc
     6181 agatactcta ctgcccattg agcaatactg aattcatcac tgtaaagcac ttcgatttct
     6241 cttaaaagtt tgttgcggat gacgataccg ttattaatgt tctccgcaga aaaagcaatg
     6301 tggtcggtca aagcgatcaa tacatgttca ttcaactttt ccatcaaaac agtttccgca
     6361 tgatcaatga tcgtttctgc tgcaaataaa aagcgttcat caatctgatt aagtaaattt
     6421 tgcaacttga tttgaccttc tggttccatg acaaatatcc gttcgacatc acgatcaaaa
     6481 atcaaatcat ttctttttct gtcaaatcca atcccttttc caatagctac tttttcctgt
     6541 ccaccgtcat ctaccaatac tgcattttga ttaaagatct ttttgatttt catgcgcgca
     6601 ccctttttga agatttggtt ttcacgtttg ctagaccagt tgattgcggc caaacaaaaa
     6661 tagacacgaa aaacctccta gggaaaccat gttcctcaga gatttttcat gcctagtatg
     6721 atctagtcac atgaaacgaa ttattgttaa cgtaatcaat tttatataga cagttatgtt
     6781 ttgtcaattc tttttttata attatagtaa tttactggaa ttatcagaaa taaaaggaag
     6841 aaataaatta agaaacttat gttatttaat cgttggatct tttgcttatc ttattcgttg
     6901 ttaaaaagct gaaagcgaag gaaaaaaact ctacttaact gtatttctcc gttaggacat
     6961 ctaaaaattt acgagcagca ggagaaagag gctggtcttt tttccaaatg agattcagtg
     7021 aagcttgtaa tggcggatcg agtgggatga atattttttc cgtcccataa gtattgatga
     7081 tcccatctag agctaatgca ccaaaagtcc cgttatcgac catcaaagaa gcattgtaca
     7141 ataagttata tgttccgacg atcgataact gatctatgct gaaacctagc cattcagcta
     7201 gttgactgtc cactgacgtt tgccgggaaa tgatcaaagg aacagttttc agttcctgcg
     7261 gatggatgac ggtttgcttt gctaaaggat gatttcgatg tatcaaaagt ccccaacgat
     7321 cttgggctgg cagtcgaaat gactggtatt tttgtttgtt tgtcggttcg attacgagtc
     7381 caaaatcaag taatccgcta tccagtttgt ctatgatatc atctgcattc ccgctatata
     7441 aatgaaactg gatatcagga tgcgccttga tcaacgaatg aaggctatca gaaatgaaag
     7501 agattgcttt agtttcgcct ccgccaatgt agatttctcc agagatgatt gcgtcatttg
     7561 ttaaattgtt cgccgttttt tctaccaacg acaagatttc ttttcctttt gaataaagat
     7621 atcgaccaga atccgtcaac tgtatctctc gggagccccg agtgaaaagt gtcacaccaa
     7681 gttcttcttc taaatctttc agttgttttg agagagtagg ttgcgtgata tgcagagatt
     7741 ttgctgctcg gctgatattt ttttctctag ctactgctaa aaaatacgtc agtatacgaa
     7801 tatccatttt ttccctcctg tttttaaaaa agcataccac taagtatagt taaaaggaat
     7861 agttaagtat gttttataag tattagacat gataagccgt ccgttataaa gtaaggataa
     7921 aaggagggag caaaatgaca agcctcatcg aaaaacaaat cgtcaataaa gagattcgag
     7981 taacggatcc gctctttgaa gtgatccatc agatccaagc tgaaaacgaa gagcctttag
     8041 cagcgctgaa tactgggtac catgaaccag cagatatccg caaacggcta gaaaatatca
     8101 ttagtgacaa agtagatgat acggtgactg ttctgctgcc tttttataca gatttcggca
     8161 aacatattag tatagggaaa aatgtcttta tcaatcgtca agtgatgttc gttgacttag
     8221 gtggcatctg tttagaagat tcagtattga ttggtcctcg tgtcaacctc atcacggtga
     8281 accatctaac cgatccaaaa gaacgaagag gcttgtcagt aaagccaatc cacatcaaga
     8341 aaaatgcttg gatcggagca ggagcaacta ttctgccagg cgtaacgatt ggcgagaatg
     8401 ccattgttgc agcgaatgca actgttacga aagatgtccc agacaatacc atcgttgcag
     8461 gaatccctgc caaaatcgtc aaacctgtcg aacggattat ttgaacagta agatgaaata
     8521 agagatagtg agtataagca agagattttt caaaacagga ggagaataga atgaatgatt
     8581 tatcagaaaa agtgattgtc atcatgggcg cttcaagcgg aatcggtgaa gcaacaacga
     8641 agctattagc agaaaaaggg gctaaactag ttatagctgc acgccgagaa gatcgcctaa
     8701 aagcaataaa agaatcttta ccagaagctg agctatatat tcaaacagca gatgtaagag
     8761 attttgcaca agtccaagca gttatcgatt tagcgatgga aaagttcggt cgaatcgatg
     8821 tattgtacaa taatgcagga atcatgccaa ccgctccatt agttgaaggt caccgtgatg
     8881 aatggcaaaa tatgcttgat atcaacatca tgggtgtgtt aaatggaatt tccgccgtac
     8941 ttccaatcat ggaaaaacaa aaatctgggc atatcatttc aactgattct gtggcgggac
     9001 atgttgttta tcctgattcc gccgtttatt gcggaacaaa atttgctgtc cgtgcaatca
     9061 tggaaggatt acgtcaagag caacggcaaa ataacatcaa atctacgatc atctctccag
     9121 gagctgttca aactgaatta tatcaaacca tcagcgacaa aaaggctgct cttgaacttc
     9181 atgaagcgca aaaagaatgg ggattgacct ccgaagatat agcttctgct gtagcatttg
     9241 cgatagaaac gccagaccgg atgtctgtca gtaacatgat tatccgtccg acgacacagg
     9301 aagtataatc cataacggat aatatccaaa gagaattact tgttaaatag ttattcaaac
     9361 gaccatcaat ttaaggcgtg aatggagaag aatattcttc atttacgtct ttttatgtag
     9421 aaaaagcaaa ttcatcaaaa agaaacaaat gttatttaaa tatggacatt gacttgcttt
     9481 tactttttta gttacactgt tatttaggaa aagtttcata attcaaagga gaaaaaagat
     9541 gaaagcaaag aatttattat ttagcgttat tcttttagga aatctagcag ttgccaacac
     9601 aacagtgcta gctgaagaat cgacagaaac tgtcgcaact cagacatcga gttcttcaga
     9661 aacaggaatt gaaaacgata cagagagtac tttgcagtca gctactgtct cagaaaatac
     9721 aatttcaacc gaagaaccaa caactgaaac aacagaacaa acacaaaccg aagacagtac
     9781 atcagcagaa gctcagaaca atccagagaa tgcagaagaa atcacgaacc aattgacaga
     9841 tgggcaaaca ttgacacata cccatcaagc agatttgtct gaattcgaaa actatactgg
     9901 ctatgctttt tatgctcgct catctgctaa ttctcaacaa gcgttcattg atagtattgc
     9961 ctcaactgca caaagtttgg caagtgccaa tgacttatat gcatcagtca tgattgctca
    10021 agccatcgtt gaaagtggct gggggaacag tactttggct tctgccccta attacaatct
    10081 atttgggatt aaaggaagct ataatggcca atctgttacg atgcctactt cggaatatgt
    10141 gaatgggcaa tggattacgg tgaatgccgc ttttagaaaa tatccttcgt acaaagaatc
    10201 attgcaagat aacgtaacgg tattgaagac gacttctttt cagccaggcg tttactacta
    10261 ttccggtgca tggaaaagca atacgaactc ttacaaagat gctacggctt ggctaacagg
    10321 tcgttatgcc actgcgccta attatggttc tacattgaac aatgtaatcg aaacctataa
    10381 tctgacacag tatgatacag caccaacttc aacttctccg atgtatcgtc tgtataaccg
    10441 tcatacagga gaacatttat atacattgaa tgccggagaa aaaaattatc tgccaactgt
    10501 aggctgggaa tatgaaggga ttgcttggca agcaccaaac agcggacaac ctgtctaccg
    10561 tttatacaat ccttacagtg gagaccatca ttacacaatg gcacaatctg agatcaactc
    10621 tttaacaaaa atcggttggc gttatgaagg tctaagtttt tattctggtg gttccaagcc
    10681 aatttatcga ctatttaatc caaatgaaaa aactggtacc catcactata ccttgagtgc
    10741 taaggaaaga gattggctaa caccgatggg ctggagatat gaaggaatag gattttatgg
    10801 ttattaaaaa gaggtagtga aaaagctgcc ctgcatcaag tagtaagaac agccaaacaa
    10861 aaacagattt tcatgttttt tgtttggttg aacttattac cgcagatgca agtttttgaa
    10921 caccgtttac tcaaaaaagg ttgtgacaac atcttgtcat aactttttta ttactgttta
    10981 agcatactga tccaatttct aatattcgac gggattcttg caaaaggcga tttcggaaat
    11041 ttttggcggt gtaaaatttt ctactgcaga agagctatct tctatagttt gataagaatc
    11101 aataatcttg gttttagcgt tgtgctttct ttatcatttt ttccgttcat tctacaaaaa
    11161 atttcttttc tctatacttt tctattgaga gcgttttttt tattacacag ctgattcttt
    11221 gacttttttc tttttttatt ctattattga caagtcaatc gttgacgagt caattattag
    11281 aaaggaggaa attatgtctt tagaagagat tagtcacctt ttatatcaaa tcaaattagc
    11341 cgatcaaaaa atcgtccaga tctttgaaga aaatatcggt ataagtctta ctagatacga
    11401 gatcatgatg agactgaaag aagaaaatcc attgctacaa agcagtttgc aagaaaagtt
    11461 gcagattgat caaggagcag ttactcgtca tctgaaggta ttggaagcaa atggctatgt
    11521 ttcgcgtcag agaaatcctc agaacaaccg ggaagtgtat gtagcgctaa cagaaaaagc
    11581 ccagaagaaa atcgagcatt gtgaaatgga ccataaagat acaggttccg tgctatcccc
    11641 ggctttcagc gatgtagaaa tgaaacaatt tctaacactt ttagataaat tgaataccca
    11701 actttgcaat ataacaacag aaacgaaaga ggttaataat aatggaacaa aaaaatgatt
    11761 tttcaacaat tatgactggt agaagatccg ttcgcgtata tgatgaaaca tacaaaatcc
    11821 cacacgaaga aatgctggaa atgatcaaag aagcgacgac tgcaccttct tctgtcaata
    11881 tgcaaccatg gcgctttgtg gtcgctgaaa gcgaggaagc aaaagaaatc ttgcgtcctt
    11941 tgatccgttt caatacgaga caaaatgata cttcttctgc aatggtcatg atttttggcg
    12001 atatgcaatg ttacgaatat ggcgaagaaa tctataacca agcttacgaa tcagggaaga
    12061 tgccaaaaga agtcagagat caacaattag ctgcgatcat tccttattac aagagttttt
    12121 caagagaaga aatgaacgat gtagtcaaag tcgattctag cttagcggct atgcaattca
    12181 tgttagttgc gcgtgatcat ggctatgaaa caaatccaat tggtggattc gaagcagatc
    12241 agttggcaga ggcatttggt ttggataaag accgttatgt tccagttatt attttatcaa
    12301 taggaaaagc ggtagaagaa ggttacgagt ctgttcgttt agcaccagaa aagatcacta
    12361 cgttcgaata aaaggttttc agttactatt cagtagctat tgcttttttt gaatcgtgtg
    12421 tggtaaccta ataaaaaagg aggtcggaaa aatgactgca tcgatgaaat tacgtttcga
    12481 acttttgaat aacaactaaa taaattcaaa agacatgtat aaacaacaat ttcatggatg
    12541 gagtatgtcc attttttcga acgacagtag aataggtgaa agctatgaca gatttggtga
    12601 tttagtcata gttatttcgt tcagagtagg aaaagatgtg atgcagtttt tttgcaaaca
    12661 gatttttctg ctctttttta gtatcgataa ttgttgtttt acatgaaata ggagtgtaaa
    12721 acatatggaa aatttagcag taaatataac aaatctacaa gtcagctttg gcaaccagct
    12781 agaactatct attgattctc ttcgtgtcta tcagcaagat cgtataggga tcataggaga
    12841 aaatggtgtc ggtaaatcga ctttgctcaa actaatagcc ggtgaacttt ttcccgatca
    12901 tgggaaaatc caaacagaga tcaccttcaa ctacctgcct caattaacct atctcgctga
    12961 agcaaaggac ctaaatttgg aattagccag tcatttccag ttaagactgg aagaaacttc
    13021 agagcggaaa tggagcggag gggaagaacg aaagatcgag ttgatacgtc ttctttcttc
    13081 ttatgaacaa gggatgcttc tagacgagcc aacaacccat ctagatagaa aaagtattga
    13141 tcgactgatt gaagagcttc gttattatta tggtacgctg gtttttgtta gtcatgatcg
    13201 ctattttcta gatgagctag catcgaaaat ctgggaagta aaagacggag aaatccgaga
    13261 gttttcgggg aattatagtg cctatctcac tcaaaaggaa ttggagaaaa agactcagct
    13321 acgagaagca gagtcgatca tgaaagagaa aaaacgattg gaaaaatcga tccaagaaaa
    13381 gaaaaaacaa gcggaaaagt tggaaaaagt gtccagtaaa aagaaaaagc aacaaatcag
    13441 accggatcgg ttgtcttcct ctaaacaaaa agacagtgta caaaaagcca tccaaaagaa
    13501 tgcgaaaaca ttagagagaa gactccaaaa aataggagaa acaaccaagc cgcagcagat
    13561 gaaacaaatc cgttttccag taccaaaatc tcttgaactc cacagccgct atcccatcat
    13621 gggacaaaat gtccaattgg aaagaagtgg gagaacatta ctggtaaatg gtgattttca
    13681 gttttcttta ggtaaaaaaa tcgcgattgt cggtgaaaat ggttcaggta agacaacctt
    13741 attagaacat atccgcaaac aaggagaagg aatccttctc tctccgaaag taagctttca
    13801 agtatatcag caaaagggtt atcaaatgac atctgaagaa tccatcattc gttttgtcat
    13861 gagacaaaca gagttttcag aatcgcttgt ccgtagtttg ctgaatcact tagggtttgc
    13921 tcaggaaact ttgacgaaac cgttatgtac attaagtggg ggagaagcga cccgtctgac
    13981 gattgctttg ctttttacta agccaagtaa tgtgttgctg ttagatgaac cgactaattt
    14041 tattgatatg gcaacgatcg aagctttaga gaagctaatg caaatatatc cgggaacgat
    14101 tttgtttact tctcatgatt cttactttgt cgagcgtacg gctgatgaag tttatgaaat
    14161 aaaagggcag aaaataaaaa aagtacttac gagaaatttt taaatgtgct acgatgattt
    14221 tcgtgacaaa tttaaaggag tggtacagat tgcctacaaa taaaaaagaa ggaataattt
    14281 ttacaacaat gatgtgtttt ttgatggtct tggggatgag cgcgtataat ttatggctgc
    14341 atcaagatct tcatttatca agtttgttga ttggtctagt gcctggattc gtggtggctt
    14401 tcattttgga tgtcttcatc atcggtgtgc tggcgaaaaa aattgccttt aaactaccag
    14461 taaatccaga aagcaaggtc caaatgatct taactatttc atgcttgatg gttttaggaa
    14521 tggtgacatg tatgtcttta ttcggtgtga tcatggaaca aggaatacct gatcaattat
    14581 tctctgctta tatgaatgct tggaaaatga atgtgattgc cgctttaccg ttgcagttga
    14641 tcatcgttgg cccgctttca agaagtgtgc taaaagcaat tcaaagtaat gaatgatgga
    14701 acactgttat ttgaaaaaag gccttggcat gctttttgtc atagtctctt gaatgcagtt
    14761 ctagaaaaat agtgatccga acgataggtt ttggcctgtc gttcggatcg ctttttcttt
    14821 tccaactgta ttgctctttt attgaagata atttgctctt caatagatat ttctagaaag
    14881 gttctgttta tcccttactc aaaaaactgc tgcatttgtt ctcttacttg ctgacaccat
    14941 tggagttcct gctgacaaag cataattctg cgctggatca caacataacg tccaaattct
    15001 tgtttcttgt ctagcgagag gtcattcaat tttttttgat ttttttgcat gattttgttc
    15061 agctgttgtt ctctagtgaa tagcagtcca gtagctgttg ttttatcgag cgtcgaaaaa
    15121 gcatagattt ttgctagaaa ttcatctttt tgcgtaggag cgggagtttc ctctttgatc
    15181 cattcctcta caagagcacg tccttcatca gtcaagtggt agatcttttt ttgagagtgc
    15241 tcgtctttgt ccaaaacggt cacataaccc tgctggtcta acttggcaag cgttgtatag
    15301 atctgactgt gatgggcttc ccaaaaaatt gtgatcagct gcttcaattc atacccagaa
    15361 cgtggtttgg ataaaagcac gcataataat atataggcta aagtattcat aaaaatccta
    15421 cctctcgtct tattttcttt attatatcac agtaaagttt ccacgtttta catgtgcata
    15481 tttacatgta aaataaatca tgtatgatgc taatagagag aaagggatgg aaatattgga
    15541 gaatcaaata gatatacaag aacaaacaaa tgaagaaaca aaggggaaaa gttcagcgct
    15601 agttgtagca gctacctgta tgatcgcttt tatgggagtg ggtctagtag acccaatctt
    15661 aaaaacgatt gctgcacagt taaacgctac gccagctgaa acgaccctgt tatttactag
    15721 ttacatgtta gtcactggtg tggtgatgct atttacaggt ttcttatcta gtcggatcgg
    15781 tttgaaaaaa acattgatga caggattgtt tatcatcgtt gtattcgctg gtcttggcgg
    15841 attatctggg aatatcggaa tgctgattgg gttacgtgcc ggctggggtg tcgggaatgc
    15901 tttatttgtc tctactgctt tagcaacgat cgtcagtatt ttagttggta acacagaaaa
    15961 agcaatcatg atgtatgaag cagcacttgg ctgcggaatg gctgttggcc ctctagtcgg
    16021 tggggtcttg ggcagtggtt catggcgtta tccatttttt ggggtagcat ttttgatgtt
    16081 ttgcggtttt atagccctag cggtactttt acctgaaact gagaaaccaa agagaaaagt
    16141 aggcctttgg gaaggtgtca aagcgttaag caatcataaa cttcgttcag ttggactaat
    16201 cgcattgtta tataatttcg gattctttac tttacttgcg tatgcgccat ttttattgat
    16261 tggctattct gaattagaag tcggttttgt attttttggc tggggtgtgc ttctggctat
    16321 tgcttcgatt ttcgttgcac cggctcttga gcggaagttt acgacttatc ggacaatttt
    16381 agcagcattt gtcttattca ttatttgttt gctgttatta ggagctggaa cttctatgcc
    16441 agtccttgta ccgatcagca ttgtgttagc aggatttttc caaggaatta tcaatacact
    16501 gttgacgacg attgctatgg aaataccagg tctgcaacga aacgttgctt cgtccagcta
    16561 tagttttgtc cgctttttcg gtggagcttt agcaccattt attgcaggtg tgattggtga
    16621 acatattggt gaaagctatg cgttttattt tgcaggtgcc attgttctta tcagtgtatg
    16681 ttgtatcatt tatcaccgta attattttgc tacaaatgaa gaagaataag aaatcagagg
    16741 ttgtgaaaaa gctgtcctgc atcaagtcat aagaa
//
LOCUS       DARPZF010000202         7959 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.guided.086, whole genome shotgun sequence.
ACCESSION   DARPZF010000202 DARPZF010000000
VERSION     DARPZF010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.guided.086"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            128..1564
                     /locus_tag="SLE65_003054"
     CDS             128..1564
                     /locus_tag="SLE65_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEI8450247.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="SLE65_003055"
     CDS             1753..4200
                     /locus_tag="SLE65_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEI8450248.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="SLE65_003056"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="SLE65_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEI8450249.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="SLE65_003057"
     CDS             complement(5690..6793)
                     /locus_tag="SLE65_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEI8450250.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="SLE65_003058"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="SLE65_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HEI8450251.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2664 a         1359 c         1729 g         2207 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacatat ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattactt
//
LOCUS       DARPZF010000203         7777 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.guided.088, whole genome shotgun sequence.
ACCESSION   DARPZF010000203 DARPZF010000000
VERSION     DARPZF010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7777
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.guided.088"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            242..1210
                     /locus_tag="SLE65_003059"
     CDS             242..1210
                     /locus_tag="SLE65_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HEI8450252.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1203..2234
                     /gene="vanA"
                     /locus_tag="SLE65_003060"
     CDS             1203..2234
                     /gene="vanA"
                     /locus_tag="SLE65_003060"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HEI8450253.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2240..2848
                     /locus_tag="SLE65_003061"
     CDS             2240..2848
                     /locus_tag="SLE65_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HEI8450254.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            3276..4187
                     /gene="vanY"
                     /locus_tag="SLE65_003062"
     CDS             3276..4187
                     /gene="vanY"
                     /locus_tag="SLE65_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HEI8450255.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            4340..4825
                     /gene="vanZ"
                     /locus_tag="SLE65_003063"
     CDS             4340..4825
                     /gene="vanZ"
                     /locus_tag="SLE65_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HEI8450256.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(5112..5441)
                     /locus_tag="SLE65_003064"
     CDS             complement(5112..5441)
                     /locus_tag="SLE65_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8450257.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            5746..6075
                     /locus_tag="SLE65_003065"
     CDS             5746..6075
                     /locus_tag="SLE65_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEI8450258.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            6065..6352
                     /locus_tag="SLE65_003066"
     CDS             6065..6352
                     /locus_tag="SLE65_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEI8450259.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(6631..7194)
                     /locus_tag="SLE65_003067"
     CDS             complement(6631..7194)
                     /locus_tag="SLE65_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8450260.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
BASE COUNT         2565 a         1297 c         1545 g         2370 t
ORIGIN      
        1 ctggtgtcat ccaccaacat caaaaagtat agagccataa ttttttagga aaatctcaag
       61 gttatcttta ctttttctta ggaaattaac aatttaatat taagaaacgg ctcgttctta
      121 cacggtagac ttaataccgt aagaacgagc cgttttcgtt cttcagagaa agatttgaca
      181 agattaccat tggcatcccc gttttatttg gtgcctttca cagaaagggt tggtcttaat
      241 tatgaataac atcggcatta ctgtttatgg atgtgagcag gatgaggcag atgcattcca
      301 tgctctttcg cctcgctttg gcgttatggc aacgataatt aacgccaacg tgtcggaatc
      361 caacgccaaa tccgcgcctt tcaatcaatg tatcagtgtg ggacataaat cagagatttc
      421 cgcctctatt cttcttgcgc tgaagagagc cggtgtgaaa tatatttcta cccgaagcat
      481 cggctgcaat catatagata caactgctgc taagagaatg ggcatcactg tcgacaatgt
      541 ggcgtactcg ccggatagcg ttgccgatta tactatgatg ctaattctta tggcagtacg
      601 caacgtaaaa tcgattgtgc gctctgtgga aaaacatgat ttcaggttgg acagcgaccg
      661 tggcaaggta ctcagcgaca tgacagttgg tgtggtggga acgggccaga taggcaaagc
      721 ggttattgag cggctgcgag gatttggatg taaagtgttg gcttatagtc gcagccgaag
      781 tatagaggta aactatgtac cgtttgatga gttgctgcaa aatagcgata tcgttacgct
      841 tcatgtgccg ctcaatacgg atacgcacta tattatcagc cacgaacaaa tacagagaat
      901 gaagcaagga gcatttctta tcaatactgg gcgcggtcca cttgtagata cctatgagtt
      961 ggttaaagca ttagaaaacg ggaaactggg cggtgccgca ttggatgtat tggaaggaga
     1021 ggaagagttt ttctactctg attgcaccca aaaaccaatt gataatcaat ttttacttaa
     1081 acttcaaaga atgcctaacg tgataatcac accgcatacg gcctattata ccgagcaagc
     1141 gttgcgtgat accgttgaaa aaaccattaa aaactgtttg gattttgaaa ggagacagga
     1201 gcatgaatag aataaaagtt gcaatactgt ttgggggttg ctcagaggag catgacgtat
     1261 cggtaaaatc tgcaatagag atagccgcta acattaataa agaaaaatac gagccgttat
     1321 acattggaat tacgaaatct ggtgtatgga aaatgtgcga aaaaccttgc gcggaatggg
     1381 aaaacgacaa ttgctattca gctgtactct cgccggataa aaaaatgcac ggattacttg
     1441 ttaaaaagaa ccatgaatat gaaatcaacc atgttgatgt agcattttca gctttgcatg
     1501 gcaagtcagg tgaagatgga tccatacaag gtctgtttga attgtccggt atcccttttg
     1561 taggctgcga tattcaaagc tcagcaattt gtatggacaa atcgttgaca tacatcgttg
     1621 cgaaaaatgc tgggatagct actcccgcct tttgggttat taataaagat gataggccgg
     1681 tggcagctac gtttacctat cctgtttttg ttaagccggc gcgttcaggc tcatccttcg
     1741 gtgtgaaaaa agtcaatagc gcggacgaat tggactacgc aattgaatcg gcaagacaat
     1801 atgacagcaa aatcttaatt gagcaggctg tttcgggctg tgaggtcggt tgtgcggtat
     1861 tgggaaacag tgccgcgtta gctgttggcg aggtggacca aatcaggctg cagtacggaa
     1921 tctttcgtat tcatcaggaa gtcgagccgg aaaaaggctc tgaaaacgca gttataaccg
     1981 ttcccgcaga cctttcagca gaggagcgag gacggataca ggaaacggca aaaaaaatat
     2041 ataaagcgct cggctgtaga ggtctagccc gtgtggatat gtttttacaa gataacggcc
     2101 gcattgtact gaacgaagtc aatactctgc ccggtttcac gtcatacagt cgttatcccc
     2161 gtatgatggc cgctgcaggt attgcacttc ccgaactgat tgaccgcttg atcgtattag
     2221 cgttaaaggg gtgataagca tggaaatagg atttactttt ttagatgaaa tagtacacgg
     2281 tgttcgttgg gacgctaaat atgccacttg ggataatttc accggaaaac cggttgacgg
     2341 ttatgaagta aatcgcattg tagggacata cgagttggct gaatcgcttt tgaaggcaaa
     2401 agaactggct gctacccaag ggtacggatt gcttctatgg gacggttacc gtcctaatcg
     2461 tgctgtaaac tgttttatgc aatgggctgc acagccggaa aataacctga caaaggaaag
     2521 ttattatccc aatattgacc gaactgagat gatttcaaaa ggatacgtgg cttcaaaatc
     2581 aagccatagc cgcggcagtg ccattgatct tacgctttat cgattagaca cgggtgagct
     2641 tgtaccaatg gggagccgat ttgattttat ggatgaacgc tctcatcatg cggcaaatgg
     2701 aatatcatgc aatgaagcgc aaaatcgcag acgtttgcgc tccatcatgg aaaacagtgg
     2761 gtttgaagca tatagcctcg aatggtggca ctatgtatta agagacgaac cataccccaa
     2821 tagctatttt gatttccccg ttaaataaac ttttaaccgt tgcacggaca aactatataa
     2881 gctaactctt tcggcaggaa acccgacgta tgtaactggt tcttagggaa tttatatata
     2941 gtagatagta ttgaagatgt aaggcagagc gatattgcgg tcattatctg cgtgcgctgc
     3001 ggcaagatag cctgataata agactgatcg catagagggg tggtatttca caccgcccat
     3061 tgtcaacagg cagttcagcc tcgttaaatt cagcatgggt atcacttatg aaaattcatc
     3121 tacattggtg ataatagtaa atccagtagg gcgaaataat tgactgtaat ttacggggca
     3181 aaacggcaca atctcaaacg agattgtgcc gtttaagggg aagattctag aaatatttca
     3241 tacttccaac tatatagtta aggaggagac tgaaaatgaa gaagttgttt tttttattgt
     3301 tattgttatt cttaatatac ttaggttatg actacgttaa tgaagcactg ttttctcagg
     3361 aaaaagtcga atttcaaaat tatgatcaaa atcccaaaga acatttagaa aatagtggga
     3421 cttctgaaaa tacccaagag aaaacaatta cagaagaaca ggtttatcaa ggaaatctgc
     3481 tattaatcaa tagtaaatat cctgttcgcc aagaaagtgt gaagtcagat atcgtgaatt
     3541 tatctaaaca tgacgaatta ataaatggat acgggttgct tgatagtaat atttatatgt
     3601 caaaagaaat agcacaaaaa ttttcagaga tggtcaatga tgctgtaaag ggtggcgtta
     3661 gtcattttat tattaatagt ggctatcgag actttgatga gcaaagtgtg ctttaccaag
     3721 aaatgggggc tgagtatgcc ttaccagcag gttatagtga gcataattca ggtttatcac
     3781 tagatgtagg atcaagcttg acgaaaatgg aacgagcccc tgaaggaaag tggatagaag
     3841 aaaatgcttg gaaatacggg ttcattttac gttatccaga ggacaaaaca gagttaacag
     3901 gaattcaata tgaactatgg catattcgct atgttggttt accacatagt gcgattatga
     3961 aagaaaagaa tttcgttctc gaggaatata tggattacct aaaagaagaa aaaaccattt
     4021 ctgttagtgt aaatggggaa aaatatgaga tcttttatta tcctgttact aaaaatacca
     4081 ccattcatgt gccgactaat cttcgttatg agatatcagg aaacaatata gacggtgtaa
     4141 ttgtgacagt gtttcccgga tcaacacata ctaattcaag gaggtaagga tggcggaatg
     4201 aaaccaacga aattaatgaa cagcattatt gtactagcac ttttggggta acgttagctt
     4261 tttaatttaa aacccacgtt aactaggaca ttgctatact aatgatacaa cttaaacaaa
     4321 agaattagag gaaattatat tgggaaaaat attatctaga ggattgctag ctttatattt
     4381 agtgacacta atctggttag tgttattcaa attacaatac aatattttat cagtatttaa
     4441 ttatcatcaa agaagtctta acttgactcc atttactgct actgggaatt tcagagagat
     4501 gatagataat gttataatct ttattccatt tggcttgctt ttgaatgtca attttaaaga
     4561 aatcggattt ttacctaagt ttgcttttgt actggtttta agtcttactt ttgaaataat
     4621 tcaatttatc ttcgctattg gagcgacaga cataacagat gtaattacaa atactgttgg
     4681 aggctttctt ggactgaaat tatatggttt aagcaataag catatgaatc aaaaaaaatt
     4741 agacagagtt attatttttg taggtatact tttgctcgta ttattgctcg tttaccgtac
     4801 ccatttaaga ataaattacg tgtaagatgt ctaaatcaag caatctgatc tttcatacac
     4861 ataaagatat tgaatgaatt ggattagatg gaaaacggga tgtggggaaa ctcgcccgta
     4921 ggtgtgaagt gaggggaaaa ccggtgataa agtaaaaagc ttacctaaca ctatagtaac
     4981 aaagaaagcc caattatcaa ttttagtgct gaggaattgg tctctttaat aaatttcctt
     5041 aacgttgtaa atccgcattt tcctgacggt acccccaaac taagatttca tagatagatt
     5101 ttctgataac tttaaaaaac acgaatagcg gaaaggatgt cttcattcgc taaagagtaa
     5161 taaactactt ttccatcttg acgtgatttt gccattccat gtttttttaa aaaacgtaaa
     5221 tggtgtgacg ttgtagcgac actagcagta agtatttctg ctaaatcaca gacgcacatt
     5281 tccttatagg tttctaaagc atagaaaatt ttaattctag aaaaatcgct gaaacatttc
     5341 cctaacacaa gtaagtttga aaaatctttt tgatccaatt tattttttat tccatttact
     5401 ttttctttat gtacgacagt cacttggcaa acttttttca ttcatctcac ctcacattca
     5461 aacgattatt tgaatgaagt atacctattt gatcactctt ttgtcaatct accttaattc
     5521 caatacacta ttataagcaa tttcatgtat tgaagtaaac ttacttgcaa gtgcgttttt
     5581 gattccaagt taaaaacata ttattattct acataatttc ctaatcaaat aaaactcctt
     5641 tgaaaattgt tctaaaggag ttttattatt ttgtatttct actaaaaata gcgtacaatg
     5701 taattactaa gtaattacga aatgtaaaat aatggaggaa ataatatgat tacaaaaaca
     5761 agaaaacaag gaaattctat tatgttaacg gtccctaaag aattcgatgt gcccaatggt
     5821 gttgaagtag aagctaagct tgtagagaat ggtatccttt atgagtttgt agagcctaaa
     5881 aaagaatttt ttgattttag tgaagatatt ttggctgata ttctttcaga aggttatagc
     5941 aaacaagaga tcttaaaaga atttagaaat agaaaaaatg cgttaacttc tgcatttaaa
     6001 tctattgctg aagatactgt tgcaaattct aaaccgatga caaaagagga gttggcagca
     6061 gaaattggct tatgagattc taccttctaa acacgtaata aagtatctaa aaaaattaaa
     6121 agagaaaaca ttaaaagaac aatttttaac gataatttat gatgagatag cagttcgtcc
     6181 tcattcggga gaacaaaaaa cgggtgattt atcaggaatt tgggctattg gattcaagta
     6241 tgcaggtacg acatatcgcg ttgcatatga aattaaagat aatgcagtga tacctatctt
     6301 actatgtgga acgcatgaaa atttttatga acaattaaaa aagattaggt aagaacccaa
     6361 tgtttcaact tgagaggata gacgacactt taaaagataa tttttaacag ctgagagttg
     6421 taatacccta taattttaaa ccactaacct atatatttat gaaaaataga aaaaattaaa
     6481 acgcatttta agcctctttc aaattaaaag cttcatcctt atgcacaaag agggcttaaa
     6541 atgcgttatt ttatattgtt ttttagtaat aataaaaaaa tcactctaat tctcccataa
     6601 atattataga ttcctaaaga ttaaaataga ttattcccta ttgtctttta agtagcggta
     6661 gagtgttgcc ttgctaatac cagtcatttc cgtaatttct tttacgctat aaacctgact
     6721 tttatacaat tttactgctc gatcaacatc tttctggttc actcgtggac ggccaccttt
     6781 acgacctctc gcacgtgcac ttttcaaacc ttctttggta cgttcaacaa ttaaatcacg
     6841 ttcgaactga ctaaatgctt ggaagacagt catcattaag cgtccgtgag gcgtgctggt
     6901 atcgaagttt tctttcaagc tcaccagctt aacatggtgt tcttcaaaat aggtaacaag
     6961 gtcaatcaaa tcctttgtac tacgacccaa tcgagaaaaa ctttctacaa ttaccgtatc
     7021 tcccggacga attttatctt ttaaacgatt tagttgggga cgaaccgctt tggttcccgt
     7081 cattttctca gttaggattt cattacaatt ttgttcattg agtaagtcta attgacgatt
     7141 tagttcttgt gaacgtgtac tcactcgggc ataaccataa atgtatccac tcatgctttt
     7201 cttcctttcg tactttaatt ctggcttgat tgtatcataa aagggagtta tagatacata
     7261 gttaatgcaa caagttatga tacaaaatat gacctctttt atttaataaa agaggtcatt
     7321 tcattttgtc tcataatcga ttgtttttga tacgagtgtg tatacgaaat aaacaaaaaa
     7381 atcttaagta aatttctaga tacctaattt aatcctaact agtgtatcct aaagttaata
     7441 acgagtttat cacaatgaaa attataaaat gctcccatat tagatataac atgcaatatt
     7501 tgaattagaa ctacaaaatt tattcgtttt ataaagtaaa taatgttgag atactaagga
     7561 atagaatatt ataaggaatt gagctgaatg tattggataa aaaaagaata actttattag
     7621 agatggacta taaaaatgct cgtaattttc ttctgaagtc tgaaagctat ttgaatgctc
     7681 agctaccaga atatattagt tttgacgaaa ctttaaaatc tgctaaaaaa gttttaactt
     7741 cgccgtttgt ataattaagc gagacaaata aaaaagc
//
LOCUS       DARPZF010000204         6752 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.guided.092, whole genome shotgun sequence.
ACCESSION   DARPZF010000204 DARPZF010000000
VERSION     DARPZF010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6752
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.guided.092"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            111..194
                     /locus_tag="SLE65_003068"
     CDS             111..194
                     /locus_tag="SLE65_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEI8450261.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            319..1056
                     /gene="erm(B)"
                     /locus_tag="SLE65_003069"
     CDS             319..1056
                     /gene="erm(B)"
                     /locus_tag="SLE65_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEI8450262.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1226..1486
                     /locus_tag="SLE65_003070"
                     /pseudo
     CDS             1226..1486
                     /locus_tag="SLE65_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1649..2314
                     /locus_tag="SLE65_003071"
                     /pseudo
     CDS             1649..2314
                     /locus_tag="SLE65_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2350..2595
                     /locus_tag="SLE65_003072"
     CDS             2350..2595
                     /locus_tag="SLE65_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEI8450263.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2698..3567
                     /locus_tag="SLE65_003073"
     CDS             2698..3567
                     /locus_tag="SLE65_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HEI8450264.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3548..4282
                     /locus_tag="SLE65_003074"
     CDS             3548..4282
                     /locus_tag="SLE65_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEI8450265.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4315..5230
                     /gene="ant(6)"
                     /locus_tag="SLE65_003075"
                     /pseudo
     CDS             4315..5230
                     /gene="ant(6)"
                     /locus_tag="SLE65_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
     gene            5227..5769
                     /gene="sat4"
                     /locus_tag="SLE65_003076"
     CDS             5227..5769
                     /gene="sat4"
                     /locus_tag="SLE65_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HEI8450266.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5862..6656
                     /locus_tag="SLE65_003077"
                     /note="aph(3')-IIIa"
     CDS             5862..6656
                     /locus_tag="SLE65_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HEI8450267.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT         2366 a         1016 c         1407 g         1963 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaacca ttttgtgtat aataggaatt
       61 gaagttaaat tagatgctaa aaatttgtaa ttaagaagga gggattcgtc atgttggtat
      121 tccaaatgcg taatgtagat aaaacatcta ctgttttgaa acagactaaa aacagtgatt
      181 acgcagataa ataaatacgt tagattaatt cctaccagtg actaatctta tgacttttta
      241 aacagataac taaaattaca aacaaatcgt ttaacttctg tatttattta cagatgtaat
      301 aacttcagga gtgattacat gaacaaaaat ataaaatatt ctcaaaactt tttaacgagt
      361 gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa aagaaaccga taccgtttac
      421 gaaattggaa caggtaaagg gcatttaacg acgaaactgg ctaaaataag taaacaggta
      481 acgtctattg aattagacag tcatctattc aacttatcgt cagaaaaatt aaaactgaac
      541 attcgtgtca ctttaattca ccaagatatt ctacagtttc aattccctaa caaacagagg
      601 tataaaattg ttgggagtat tccttaccat ttaagcacac aaattattaa aaaagtggtt
      661 tttgaaagcc atgcgtctga catctatctg attgttgaag aaggattcta caagcgtacc
      721 ttggatattc accgaacact agggttgctc ttgcacactc aagtctcgat tcagcaattg
      781 cttaagctgc cagcggaatg ctttcatcct aaaccaaaag taaacagtgt cttaataaaa
      841 cttacccgcc ataccacaga tgttccagat aaatattgga agctatatac gtactttgtt
      901 tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta aaaatcagtt tcatcaagca
      961 atgaaacacg ccaaagtaaa caatttaagt accgttactt atgagcaagt attgtctatt
     1021 tttaatagtt atctattatt taacgggagg aaataattct atgagtcgct tttttaaatt
     1081 tggaaagtta cacgttacta aagggaatgg agataaatta ttagatatac tactgacagc
     1141 ttccaagaag ctaaagaggt ccctagcgcc tacggggaat ttgtatcgat aaggggtaca
     1201 aattcccact aagcgctcgg gaccccttgt aggaaaatgt cctaagtgtg gcaacaatat
     1261 tgtattaaaa aaatcgtttt atggttgttc aaattatcct gaatgtaagt ttactttagc
     1321 tgaacatttt agaaagaaaa aactaaccaa aacgaatgta aaagaattac tggagggaaa
     1381 agaaaccctg gtaaaaggaa tcaaaaacaa agagaaaaag ccctacaatg ccgttgtaaa
     1441 aattggggaa aagggatata ttgattttat ctctttttca aaataaacat ggggctgacc
     1501 caaaagtagc tcctatatga aaaatagagg tctttccatt tagatagtag tggaaagacc
     1561 tctatttatc ttttgaaagt gaatacaaaa ataaagcaca ctctgctata atataggtga
     1621 ttaatccatt tgagagaggt gctttatcat gtatcaaaat tataccataa accaactttg
     1681 tttgcctata gatcttgaaa ttaaattaga agaaaatgat tttgctcatg ccattgtgca
     1741 gtttgttgac tctattcccg atgaagtctt tcttccttat tatcaatcta tgggtagacc
     1801 ccaatatcat cctcgtatgc tactttccat tattctttgt gcctatattc aaggggttta
     1861 ttcgggccgc caaatacaaa atatgctgat agatagtatt cggatgcgct acttatctca
     1921 agagcaattc cctaactttc gtactattaa tcgttttcgc gttcatccga ttatgaacga
     1981 tattctagat cattcatttg ttcaatttcg tgagctactg gttcaaagtg gcttaatcag
     2041 tggcagtgct ctatacattg atggtacaaa aattgaagcg gatgcgaata aatactcttt
     2101 cgtttggaaa aaaagtattt taaagtataa ggatagcctt gatcaaaaag cccttgaaaa
     2161 ctaccaacaa atggtggaaa caaaaatctt acctgagtta atagatgatt taaaggatga
     2221 actttctata gaagagattg aaaggattcg tcaatctttg gaagaaaagg aaaatcaatt
     2281 aattgaagcg attgaccaaa ccgaaacagt agaagggggc tgacccatta ttaataagga
     2341 gtggacaaca tgattgatgt aaatgagcta ttggaagaag ctattagaga aactgaaaat
     2401 ctaaatgatg gcgaagtttt tcttgttaaa gatttattca agggatatgt ggggaatagg
     2461 atacccagaa aggatcgact tctgcttgga acgttatttt taaaccatgt tagcaaaatg
     2521 aatggtaatt taaaggctat tgaaaagact tcatctaatc agcagaggta taaaaagaca
     2581 attgataagt tttaactatc ttttgtgaaa ttaaaaaaat tataaatatg ttgagtagaa
     2641 gcaaaagatt tggcttggaa tttttacagc agtgaatcga taaaaggagc atgcttgatg
     2701 gtagataata ttattaaatc agtagcagag aaattatcct ctctgtctta tatagaaggt
     2761 attgttttag gtggttcacg tgcaaggggc acccatacag aggattcgga tatagatatc
     2821 ggcatctatt acaattcaga atcatttgac ataaatacta ttaatcaatt cgctacaaag
     2881 ctggatgatg agcatagaaa taaccttgtt gtacctcccg gagcatgggg tgattggatt
     2941 aatggcggcg gatggttagt cataaacggg tatcatgtgg atttaatttt acgtgatatt
     3001 aaacgtgtgg aacaaataat gaaagataca gagcacggaa ttgttactgc caattatcag
     3061 actgggcatc cccatggtta tattagtgca atgtatcgag gagaattagc gattagcaaa
     3121 atactatatg ctaagaatga aagcttatgc gaattaaaaa aacaggcaga aacttatccc
     3181 aatgctttgc agaaaagttt agttaacttt tttatgtttg aagcagggtt ctctttaatg
     3241 tttgtaaaag caaattcggg aacagacgat aaatattata ttgcgggtca tgtttttcgt
     3301 atagtttcat gtttaaatca agtgttattt gcatgtaata atgcttattg tatcaacgaa
     3361 aagaaagcta taaaactgct tgaaactttt gaacataaac ctgaaaaata taccgagaag
     3421 gtaaatcata tttttgaagt actcggtatc tcactttttg aatgctacga catgaccgag
     3481 aagctttata atgaagtgaa tgaaattgta tcggagataa ataacttttt aaacgaggag
     3541 agttcagatg aaagaaaaca aatatgatga taatatattt tttcaaaaat acagtcaaat
     3601 gagtcgctcg cagaaaggac tggctggtgc gggagaatgg gagactttga aaaagatgct
     3661 acctgatttt aagggtaagc gtgtgcttga tttaggatgc ggctatggat ggcactgtat
     3721 atatgcgatg gaaaacggtg cttcctctgt agtaggtgtt gatatttctc ataaaatgct
     3781 cgaagtagca aaaggaaaaa cccattttcc acagattgaa tatgaatgct gtgccataga
     3841 agatgtggat ttcccagagg agagctttga tgtaatacta agttcgcttg cgtttcatta
     3901 tgtagcagac tatgagaatt taataaaaaa gatatatagg atgctgaagg ctggtggcaa
     3961 tttagttttt acagttgaac atcctgtttt tactgctcat ggaacacaag actggtatta
     4021 taacgaaaaa ggagaaatac tgcatttccc ggtggacaat tattattatg agggcaaacg
     4081 gacagctatg tttttggaag aaaaggttac aaaatatcat agaacactga ccacatatct
     4141 aaatacactg ctttcaaata gttttataat aaatcagatt gtggagccac agccgccaga
     4201 gaacatgatg gatattccgg ggatggcgga tgaaatgcga cgcccaatga tgctgattgt
     4261 atcggcaaaa aagaagatgt aataatatag aaaaaataaa cgaggagtat gtaaatgaga
     4321 tcagaaaaag aaatgatgga tttagtactt tctttagcag aacaggatga acgtattcga
     4381 attgtgaccc ttgaggggtc acgcgcaaat attaatatac ctaaagatga atttcaggat
     4441 tatgatatta catattttgt aagtgatata gaacctagaa ccgtttatat ctaatgatga
     4501 ctggcttaat caatttggga atataataat gatgcaaaag ccggaggata tggaattatt
     4561 cccacctgaa gaaaagggat tttcctatct tatgctattt gatgattaca ataaaattga
     4621 tcttacctta ttgcccttgg aagagttaga taattaccta aagggcgata aattaataaa
     4681 ggttctaatt gataaagatt gtagaattaa aagggacata gttccgactg atatagatta
     4741 tcatgtaaga aagccaagcg caagggagta tgatgattgc tgcaatgaat tttggaatgt
     4801 aacaccttat gttattaaag gattgtgccg taaggaaatt ttatttgcta ttgatcattt
     4861 taatcagatt gttcgccatg agctgctgag aatgatatca tggaaggtcg gcatcgaaac
     4921 aggctttaaa ttaagtgtag gcaagaacta taagtttatt gaaaggtata tatccgagga
     4981 tttgtgggag aaacttttgt ccacctaccg gatggattcc tatgaaaaca tatgggaagc
     5041 attatttcta tgccatcaat tgttcagggc ggtatccggt gaggtggcgg aaaggcttca
     5101 ttatgcctat ccggagtatg ataggaatat aacaaaatat accagggaca tgtataaaaa
     5161 atacactggt aaaaccggct gcctggatag cacatatgcc gctgatatag aagagaggcg
     5221 ggaacagtga ttacagaaat gaaagcaggg cacctgaaag atatcgataa acccagcgaa
     5281 ccatttgagg tgataggtaa gattataccg aggtatgaaa acgagaattg gacctttaca
     5341 gaattactct atgaagcgcc atatttaaaa agctaccaag acgaagagga tgaagaggat
     5401 gaggaggcag attgccttga atatattgac aatactgata agataatata tctttactac
     5461 caagacgata aatgcgtcgg aaaagttaaa ctgcgaaaaa attggaaccg gtacgcttat
     5521 atagaagata tcgccgtatg taaggatttc agggggcaag gcataggcag cgcgcttatc
     5581 aatatatcta tagaatgggc aaagcataaa aacttgcatg gactaatgct tgaaacccag
     5641 gacaataacc ttatagcttg taaattctat cataattgtg gtttcaaaat cggctccgtc
     5701 gatactatgt tatacgccaa ctttgaaaac aactttgaaa aagctgtttt ctggtattta
     5761 aggttttaga atgcaaggaa cagtgaattg gagttcgtct tgttataatt agcttcttgg
     5821 ggtatcttta aatactgtag aaaagaggaa ggaaataata aatggctaaa atgagaatat
     5881 caccggaatt gaaaaaactg atcgaaaaat accgctgcgt aaaagatacg gaaggaatgt
     5941 ctcctgctaa ggtatataag ctggtgggag aaaatgaaaa cctatattta aaaatgacgg
     6001 acagccggta taaagggacc acctatgatg tggaacggga aaaggacatg atgctatggc
     6061 tggaaggaaa gctgcctgtt ccaaaggtcc tgcactttga acggcatgat ggctggagca
     6121 atctgctcat gagtgaggcc gatggcgtcc tttgctcgga agagtatgaa gatgaacaaa
     6181 gccctgaaaa gattatcgag ctgtatgcgg agtgcatcag gctctttcac tccatcgaca
     6241 tatcggattg tccctatacg aatagcttag acagccgatt agccgaattg gattacttac
     6301 tgaataacga tctggccgat gtggattgcg aaaactggga agaagacact ccatttaaag
     6361 atccgcgcga gctgtatgat tttttaaaga cggaaaagcc cgaagaggaa cttgtctttt
     6421 cccacggcga cctgggagac agcaacatct ttgtgaaaga tggcaaagta agtggcttta
     6481 ttgatcttgg gagaagcggc agggcggaca agtggtatga cattgccttc tgcgtccggt
     6541 cgatcaggga ggatatcggg gaagaacagt atgtcgagct attttttgac ttactgggga
     6601 tcaagcctga ttgggagaaa ataaaatatt atattttact ggatgaattg ttttagtacc
     6661 tagatttaga tgtctaaaaa gctttaacta caagcttttt agacatctaa tcttttctgg
     6721 ctctttgtca aatgatgttg gtaaagagaa at
//
LOCUS       DARPZF010000205         4544 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.guided.110, whole genome shotgun sequence.
ACCESSION   DARPZF010000205 DARPZF010000000
VERSION     DARPZF010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4544
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.guided.110"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            348..1562
                     /locus_tag="SLE65_003078"
     CDS             348..1562
                     /locus_tag="SLE65_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HEI8450268.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            1593..1811
                     /locus_tag="SLE65_003079"
                     /pseudo
     CDS             1593..1811
                     /locus_tag="SLE65_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2230..2703
                     /gene="dfrF"
                     /locus_tag="SLE65_003080"
     CDS             2230..2703
                     /gene="dfrF"
                     /locus_tag="SLE65_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HEI8450269.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            2830..3486
                     /locus_tag="SLE65_003081"
     CDS             2830..3486
                     /locus_tag="SLE65_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEI8450270.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            3668..4198
                     /locus_tag="SLE65_003082"
     CDS             3668..4198
                     /locus_tag="SLE65_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEI8450271.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
BASE COUNT         1520 a          667 c          960 g         1397 t
ORIGIN      
        1 atagaatgat tttctatcag tcctagaaat tatagagccg aacaaatttg agaaccgtag
       61 cgacactcgc tgcggttctt ttttatatat tttatatgaa gtattcttta ttccttatga
      121 aaaaatatct ttaaaaataa aaaaagacga aaataaacgg ttttctataa aaagaagacc
      181 gtttattttt tgtctttatt tgtgtgaaaa acgaaaaaga gcacaacaca tcaagctttt
      241 attaattgtc tgtcttttat aaatgcaagt attaattcaa aaaaacagaa gaaaaaaaca
      301 actacacctt cttttatact cgtaatcgta gaaaggaggc gaaaaaaatg aatacattac
      361 ctatcaatac aggagataca gcattcatga ttttatgtac agcaatggtt tgcctgatga
      421 ctcctggtct agcttttttt tacggcggat tagcacggaa gaataatata ctaacgatca
      481 tgtctcaatc ttttctctcc gttgggataa caacgattat gtgggtattt ggtggattcg
      541 gattggcctt tggacgggat atcggcggtg ttattggaaa cccggcagat ttctttttga
      601 tgagacatgt tacaagcttc cccaacatgt ttcatggtgc aacgattcca tttttaatgt
      661 tctttcttta ccaactgatg tttatcgtga ttaccgttcc tttgatgaca ggagcttttg
      721 cagggagatt gaatttaaaa ggctatatta tacttgttat tttttggaat ctgctgattt
      781 atttccctgt ttgccactgg atatggggtg gcggattttt ggatcagatg ggatttagag
      841 atttcgctgg tggagcagtc atccacacga cagctggatt cggctcttta gcatgtatcc
      901 tcacacttgg tcaaagaaag attcctttag gagaaagaag tcagcatagc agtcttatgg
      961 cagctgctat cggtacagga ctgctttggt ttggctggtt cggttttaat tccggtggtg
     1021 cacttcgagc agatgaacaa gcagtcaatg catttggttc aacattcatc gctcttgcat
     1081 ttgcgatgat tacttggctg atcattgcaa aagtaaaagg aaatggcttt gattttgtcg
     1141 acgtactaac aggatccgtt gctggattgg cagccattac gccttgtgcc ggttatgtag
     1201 aagcaaaaag tgccatgctg attgggatca ttgcgggtat cgtctgtcat gctgctgttg
     1261 attttcgtaa aaagaaacaa tgggatgatg cacttgatgt gtggggtgtt catggcatgg
     1321 gcggattcac aggtacgatt ctgataggga tctttgcatc taacagccat ttactaacga
     1381 atccaagcag ctggtacttc ttagggattc aagtgattgg tgtcatcatt actgccgtgt
     1441 atgcctatgt gctgacaaca gtgattttaa aatcggcgat gcactttaca acgatcacta
     1501 ctacaaaaga agaacaagaa gaaggattgg actttttctt ctttggcaac aaactcaatt
     1561 gaaacaaatt caaatagaaa agaggaagat tcatgcaaca aagcaaaacg aaaattcctg
     1621 caaaaaaatt aacgttcttt ggctttttgg ctatgaccat ctcaatggtc gtttcattat
     1681 atgaatatcc cacattcgcg acctcaggct tcagcttagt atttttcttg ttattaggcg
     1741 gtttgctatg gtttatccct gtggcattgt gcgcagcaga gatggcaacg gtgaaaggat
     1801 gggaaaaagg tgtttcccaa acaaaaagat attaagaaac agcccatgtt tacctgcttg
     1861 caaacaaaag aatattgcta ctagactaag agatactaca taagtgtgtt ggtatctctt
     1921 ttttgttgcc gtgaaacagc agactatttc atttctgctt gattacctta aaacttatta
     1981 gtctatggtt tgtcaagggc ttgttgcgtg agaaatgctg aatatcaccc tttacaaaac
     2041 ataggctgat aagtaacttt tcaaaagcag aaaagaaatg gcaatgctta taacaatatg
     2101 atataatgca gatgaagaca aaaaaggaat ttgtcgagct ggttagttcg agataatttt
     2161 gagtttgtta agatgtggtg cacttgatgg aatcacaggt acgacatcat attatggagg
     2221 atgaaataga tgataggttt gattgttgcg aggtcaaaga ataatgttat aggcaagaat
     2281 ggtaatatac catggaaaat aaagggagaa caaaagcaat ttagagagtt aacaacgggt
     2341 aatgtggtta ttatggggcg aaagtcttat gaagaaatcg gtcatccgtt gcctaataga
     2401 atgaatattg ttgtttccac cacaacagag tatcaaggag ataatttagt ttcagttaaa
     2461 tcattagaag atgcattatt attggctaaa ggacgagatg tatacatatc tggtggatat
     2521 ggactattta aggaagcttt gcaaatagta gataaaatgt atatcacaga agtagattta
     2581 aatattgaag atggagatac attctttcca gaatttgata tcaatgattt tgaagttttg
     2641 ataggggaaa cacttggtga ggaagtgaaa tatacgagaa cattttatgt aaggaaaaaa
     2701 tgaattgagt aaattttgga tttagggtgt tttcataaat atattgcttt ttatgcatat
     2761 ataaattgtt gtaagacaaa ttccagtttg tatggggcga taaaatcaga atttgagaga
     2821 ggattgaata tgaataagga atggtctgaa cttaataaaa caatgcaggc acaaataaaa
     2881 aagaaagata cttataagag gggtattgat actttactta ctttacgaag tcagttaata
     2941 caaaccttag tatctttcaa agaagaatta tgcagagaag attttaactc aatccccttc
     3001 ataaacgctg atggttatca tagtaagacg attgcttatt ctatttggca tattttccgc
     3061 attgaagata tagttgtgca tacagtgata aatgaagatg aacaagtatt ttttgcaggc
     3121 aattatcaag agcgtatcaa ttcacctatc attacaacag gaaatgaact catgaaacag
     3181 cagattgcag acttttcaaa acagcttaat ctggaagaat tatatttata tattttcgaa
     3241 gtatgggaaa gcactgagaa aatgcttgaa cggttatctt atgatgaatt gaaaagaaaa
     3301 ataccgaaag aaagaaaagg atacttagaa tcgttgaatg tagtaaacga caatgaaaaa
     3361 gcaatttggc tgattgatta ttggtgtaat aaagatattt gtggactaat tcaaatgccg
     3421 ttttcaagac attggattat gcacacagaa gcctgtttgc gtataaagaa caagatacat
     3481 tcataggcaa aaatttcagt ttgtagaact aaggaaattg gaatttaagg aggaataaag
     3541 tatggttagt gattttataa gagcagcatt tccatggatt ttaatgggtt tatttgtagc
     3601 aatcagttgt tcccttatga gtaaaaaaga gaaataaatt cctgtttgta tttataaaag
     3661 agaaaaaatg agaaaagtag ttttatttat tgccatgagc cttgacggat atattgcgga
     3721 cggtaatggt ggagtagctt ggctaaatgg tcatggaaat gacaatgaaa acatcgacac
     3781 ttatacagaa tttaccaaag atatagatac tgtcttaatg gggtggaata cttctcatca
     3841 ggttgttact gaactttctc cgcaagaatg ggtatataat aaatttacaa cttatgtatt
     3901 aacacataaa gagtgcaatt cttcccaaca aattcatttt acaagtgaaa atcctgtttt
     3961 attattggaa cggctaaaac aagaagcagg aaaggatatt tggatttgtg gcggagcaaa
     4021 tcttgttcag cagttggtaa gcaaaaatat gattgataaa tattacattt ctgttattcc
     4081 tactctgtta ggaaatgggg ttcgtctttt gggcaacata gacagggaaa taaagttaag
     4141 gctttgtaaa acacagactt ataacggaat aaccgatttg atttatatgc gtagataact
     4201 agagagaaac agaaaagctg ttaaaccgac ggagcgatcc gaccacgttg gcgggaaaat
     4261 ccttaagatt tttccgccat gcttgcaagg gggcggttcg cttcggcggt tcggcgagct
     4321 tgcgagccgt tcaaagcccc cgttatctaa caaggggggc acaaaaaaca agaaacacta
     4381 tacactaaca agcggaaaac gctgtattta taaggcaaaa ccccattttt acagtagtga
     4441 tataaattgt acctatatca ctatgaaaat tgaatagtaa atatgagaaa gacagttgat
     4501 ttcaaaaaat aggctctttg tcaaatgatg ttggtaaaga gaaa
//
LOCUS       DARPZF010000206         2316 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.guided.142, whole genome shotgun sequence.
ACCESSION   DARPZF010000206 DARPZF010000000
VERSION     DARPZF010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2316
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.guided.142"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(38..340)
                     /locus_tag="SLE65_003083"
                     /pseudo
     CDS             complement(38..340)
                     /locus_tag="SLE65_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1054..1344)
                     /locus_tag="SLE65_003084"
     CDS             complement(1054..1344)
                     /locus_tag="SLE65_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8450272.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1552..2243)
                     /locus_tag="SLE65_003085"
                     /pseudo
     CDS             complement(1552..2243)
                     /locus_tag="SLE65_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
BASE COUNT          661 a          439 c          335 g          881 t
ORIGIN      
        1 tggatttttt catttacaca aaatatttta tactctcaac atacttgcaa agtaatacta
       61 caattcctaa cataatcgta gaatttaata atttccatag cataaagtgt ttagaaaaga
      121 acattaagaa tagttctata ataattcttg aactccatgt cttataatgt tctatcgaag
      181 cacccaaata gccaagttca tctaatctac ttgcataaac tacgtcatcc gctctcatag
      241 tcggcatata catattaaag agtaaaaaga taccccaaat ccctattagt aacaagatca
      301 gttctttgtt attcgttatt tttctattat gtttgttcat ttttatactc cttcttatat
      361 ttcctaatag agtataacat agctttaagc attacttaaa gataacttaa aagttatctt
      421 ttaaatactt aattgttaaa taccttattt gatgcaaaag aaatctacga tagtcaacaa
      481 aaaaattttc attatatcca gaaaaatttt tcttagttaa ggacctatgg attgcagtaa
      541 tgcagaattc gtcgaataaa ctgccaaaga catacaatca tattgctttt aaaattgacg
      601 aacaagatat agattcgttt gtctcaaaaa tccaaatgtt aggtttaact gtcgaaccag
      661 gacgttctcg tgtgaaaggc gaggcttctt caatttactt ttacgactat gataatcacc
      721 tcttcgagtt acataccggt actctccagg aacgtttaaa atcctacaat tccactacct
      781 gagactagta atgactagtc tctttttatg gcctctgatc cccccattga gcgaatacta
      841 atagggcttc gaattgatct gttcaatctt taagcaatat ccctcaaatg agtttggaaa
      901 gtttagtgat tcatcacaaa tacttaaata catgtagtta tatatagatt gaggttcttg
      961 tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca tccatctttc caaaacaagc
     1021 ggctaggaca tttttgtctc agccgcttgt tttctagttt attctttcat cttgtcggac
     1081 cttttttctt gggtatagac ttttctcata ttctaccaca attttgggtt tccctaacac
     1141 atgataggat ctcacaacaa attgctttct attattataa taacctgtaa cgactaactt
     1201 catcccttcg tctacttcag ctaggaagtt caaactatgg gaagcaatca aacaattgac
     1261 cccatttaaa ctgaaacgga tcaacggtct ggcactaact tgcaaagtac ggatcttatc
     1321 tactgttcca tattttttct ccataacctt cacctcaata ccattatacg aacatacatt
     1381 ccctttgtaa agaagaaact ctgttttatc tttttgactt tttgtctatt acctttctta
     1441 aaatcatatt ggcacttcct gcgaagatga aggacatgta ctaaaaaaaa gaggcagcag
     1501 tatagattac tgttgcttct ttactaattt aggtttactt gttaagaaag attatttacg
     1561 caaatgttct tcaacaattt gctgagattt atcagctgta tcttccactt catcttttgc
     1621 tttttctaac ttttgaatat attgtttcaa gcttgagttt tcagcagttg cttcgtctaa
     1681 tttcttttgt gtatctgtta actgatttct acatttgttt tttcttgtgt cagtgttgcg
     1741 atttgttgat tcaaaccatt tacagtattt tgtaattctg aaagttttgc ttgtgcttct
     1801 tgtagtcttg ctgtccaatc tgcattcaga tgattgattt catcattttt ttggttgatc
     1861 tcatctagtt tgacattgat ttcattttgt ttgctttgta gttgtgcatc cttgctgact
     1921 aattgacttt ctaagttttg tttttctgct gccgattgat ttttttggtt ttctaattca
     1981 tttacttttg tttggtattc ttggacatct gcctttgaat cttgcaatgt ctgttctttt
     2041 tgtgctagtc gagcggtaag atctgtaatc gcttgctctt tatctgtcaa tgtatgatca
     2101 agctgtgtca gattctcatt gattgtatca atatctgtct ctccacccca caaaataatt
     2161 tcatttgcgt accgcgtgcc tgtgtagcca attagacata gaaatgcaac gacaatccca
     2221 ccagtaataa atttcttttt catttgcata gctccttaat ccaatacttt tacatgctaa
     2281 aagtaagtga tctcaaacac aatgtcaagc gttttt
//
LOCUS       DARPZF010000207         2242 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.guided.144, whole genome shotgun sequence.
ACCESSION   DARPZF010000207 DARPZF010000000
VERSION     DARPZF010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.guided.144"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..148
                     /locus_tag="SLE65_003086"
     CDS             <1..148
                     /locus_tag="SLE65_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8450273.1"
                     /translation="LIVDLKLCNRTNYAVKLYKEGNMTVNQICEITNVSRASLYRKLS
                     EVNN"
     gene            362..1057
                     /gene="vanR"
                     /locus_tag="SLE65_003087"
     CDS             362..1057
                     /gene="vanR"
                     /locus_tag="SLE65_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HEI8450274.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1035..2189
                     /locus_tag="SLE65_003088"
     CDS             1035..2189
                     /locus_tag="SLE65_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HEI8450275.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          757 a          409 c          475 g          601 t
ORIGIN      
        1 tttgatagta gatttaaaac tttgcaacag aaccaattat gcggtaaagc tatataaaga
       61 aggaaatatg actgtaaatc aaatttgtga aattactaat gtatctaggg cttcattata
      121 caggaaatta tcagaagtga ataattagcc attctgtatt ccgctaatgg gcaatatttt
      181 taaagaagaa aaggaaacta taaaatatta acagcctcct agcgatgccg aaaagccctt
      241 tgataaaaaa agaatcatca tcttaagaaa ttcttagtca tttattatgt aaatgcttat
      301 aaattcggcc ctataatctg ataaattatt aagggcaaac ttatgtgaaa gggtgataac
      361 tatgagcgat aaaatactta ttgtggatga tgaacatgaa attgccgatt tggttgaatt
      421 atacttaaaa aacgagaatt atacggtttt caaatactat accgccaaag aagcattgga
      481 atgtatagac aagtctgaga ttgaccttgc catattggac atcatgcttc ccggcacaag
      541 cggccttact atctgtcaaa aaataaggga caagcacacc tatccgatta tcatgctgac
      601 cgggaaagat acagaggtag ataaaattac agggttaaca atcggcgcgg atgattatat
      661 aacgaagccc tttcgcccac tggagttaat tgctcgggta aaggcccagt tgcgccgata
      721 caaaaaattc agtggagtaa aggagcagaa cgaaaatgtt atcgtccact ccggccttgt
      781 cattaatgtt aacacccatg agtgttatct gaacgagaag cagttatccc ttactcccac
      841 cgagttttca atactgcgaa tcctctgtga aaacaagggg aatgtggtta gctccgagct
      901 gctatttcat gagatatggg gcgacgaata tttcagcaag agcaacaaca ccatcaccgt
      961 gcatatccgg catttgcgcg aaaaaatgaa cgacaccatt gataatccga aatatataaa
     1021 aacggtatgg ggggttggtt ataaaattga aaaataaaaa aaacgactat tccaaactag
     1081 aacgaaaact ttacatgtat atcgttgcaa ttgttgtggt agcaattgta ttcgtgttgt
     1141 atattcgttc aatgatccga gggaaacttg gggattggat cttaagtatt ttggaaaaca
     1201 aatatgactt aaatcacctg gacgcgatga aattatatca atattccata cggaacaata
     1261 tagatatctt tatttatgtg gcgattgtca ttagtattct tattctatgt cgcgtcatgc
     1321 tttcaaaatt cgcaaaatac tttgacgaga taaataccgg cattgatgta cttattcaga
     1381 acgaagataa acaaattgag ctttctgcgg aaatggatgt tatggaacaa aagctcaaca
     1441 cattaaaacg gactctggaa aagcgagagc aggatgcaaa gctggccgaa caaagaaaaa
     1501 atgacgttgt tatgtacttg gcgcacgata ttaaaacgcc ccttacatcc attatcggtt
     1561 atttgagcct gcttgacgag gctccagaca tgccggtaga tcaaaaggca aagtatgtgc
     1621 atatcacgtt ggacaaagcg tatcgactcg aacagctaat cgacgagttt tttgagatta
     1681 cacggtataa cctacaaacg ataacgctaa caaaaacgca catagaccta tactatatgc
     1741 tggtgcagat gaccgatgaa ttttatcctc agctttccgc acatggaaaa caggcggtta
     1801 ttcacgcccc cgaggatctg accgtgtccg gcgaccctga taaactcgcg agagtcttta
     1861 acaacatttt gaaaaacgcc gctgcataca gtgaggataa cagcatcatt gacattaccg
     1921 cgggcctctc cggggatgtg gtgtcaatcg aattcaagaa cactggaagc atcccaaaag
     1981 ataagctagc tgccatattt gaaaagttct ataggctgga caatgctcgt tcttccgata
     2041 cgggtggcgc gggacttgga ttggcgattg caaaagaaat tattgttcag catggagggc
     2101 agatttacgc ggaaagcaat gataactata cgacgtttag ggtagagctt ccagcgatgc
     2161 cagacttggt tgataaaagg aggtcctaag agatgtatat aattttggct ctttgtcaaa
     2221 tgatgttggt aaagagaaat ct
//
LOCUS       DARPZF010000208         1650 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0506
            SAMN38330024-rid20278143.guided.157, whole genome shotgun sequence.
ACCESSION   DARPZF010000208 DARPZF010000000
VERSION     DARPZF010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330024
            Sequence Read Archive: SRR26887607
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992651.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992651.1
            Genome Coverage       :: 280x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:55:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,090
            CDSs (total)                      :: 3,025
            Genes (coding)                    :: 2,945
            CDSs (with protein)               :: 2,945
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 41 of 80
            Pseudo Genes (incomplete)         :: 34 of 80
            Pseudo Genes (internal stop)      :: 20 of 80
            Pseudo Genes (multiple problems)  :: 14 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330024-rid20278143.guided.157"
                     /isolate="C0506"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..1348
                     /locus_tag="SLE65_003089"
     CDS             <1..1348
                     /locus_tag="SLE65_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HEI8450276.1"
                     /translation="DFILYLKLCNRTESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQI
                     YKMYDELYTDYHYPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAV
                     ILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKY
                     LIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNT
                     NLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLR
                     QMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFE
                     GKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGE
                     DILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1478..>1650)
                     /locus_tag="SLE65_003090"
     CDS             complement(1478..>1650)
                     /locus_tag="SLE65_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8450277.1"
                     /translation="KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEW
                     IYSSRKYINFDK"
BASE COUNT          671 a          148 c          278 g          553 t
ORIGIN      
        1 ggattttatt ctttatttaa aactttgcaa cagaaccgaa tcattaaaaa aacattatac
       61 agagccttgg gaagatgaag tttttagagt aattattgaa tataacaatg ttcctattgg
      121 atatggacaa atatataaaa tgtatgatga gttatatact gattatcatt atccaaaaac
      181 tgatgagata gtctatggta tggatcaatt tataggagag ccaaattatt ggagtaaagg
      241 aattggtaca agatatatta aattgatttt tgaatttttg aaaaaagaaa gaaatgctaa
      301 tgcagttatt ttagaccctc ataaaaataa tccaagagca ataagggcat accaaaaatc
      361 tggttttaga attattgaag atttgccaga acatgaatta cacgagggca aaaaagaaga
      421 ttgttattta atggaatata gatatgatga taatgccaca aatgttaagg caatgaaata
      481 tttaattgag cattactttg ataatttcaa agtagatagt attgaaataa tcggtagtgg
      541 ttatgatagt gtggcatatt tagttaataa tgaatacatt tttaaaacaa aatttagtac
      601 taataagaaa aaaggttatg caaaagaaaa agcaatatat aattttttaa atacaaattt
      661 agaaactaat gtaaaaattc ctaatattga atattcgtat attagtgatg aattatctat
      721 actaggttat aaagaaatta aaggaacttt tttaacacca gaaatttatt ctactatgtc
      781 agaagaagaa caaaatttgt taaaacgaga tattgccagt tttttaagac aaatgcacgg
      841 tttagattat acagatatta gtgaatgtac tattgataat aaacaaaatg tattagaaga
      901 gtatatattg ttgcgtgaaa ctatttataa tgatttaact gatatagaaa aagattatat
      961 agaaagtttt atggaaagac taaatgcaac aacagttttt gagggtaaaa agtgtttatg
     1021 ccataatgat tttagttgta atcatctatt gttagatggc aataatagat taactggaat
     1081 aattgatttt ggagattctg gaattataga tgaatattgt gattttatat acttacttga
     1141 agatagtgaa gaagaaatag gaacaaattt tggagaagat atattaagaa tgtatggaaa
     1201 tatagatatt gagaaagcaa aagaatatca agatatagtt gaagaatatt atcctattga
     1261 aactattgtt tatggaatta aaaatattaa acaggaattt atcgaaaatg gtagaaaaga
     1321 aatttataaa aggacttata aagattgatt atataatata tgaaaagcta ttataaaaga
     1381 cattagtatt aaatagttta aaaaaatgaa aaataataaa ggaagtgagt caagtccaga
     1441 ctcctgtgta aaatgctata caatgttttt accatttcta cttatcaaaa ttgatgtatt
     1501 ttcttgaaga ataaatccat tcatcatgta ggtccataag aacggctcca attaagcgat
     1561 tggctgatgt ttgattgggg aagatgcgaa taatcttttc tcttctgcgt acttcttgat
     1621 tcagtcgttc aattagattg gtactcttta
//
